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# Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Sat Jul 23 20:52:46 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/Haloperoxidase.html
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#====================================
# Aligned_structures: 9
# 1: 1a88a.pdb
# 2: 1a8q.pdb
# 3: 1a8s.pdb
# 4: 1b6g.pdb
# 5: 1brt.pdb
# 6: 1c4xa.pdb
# 7: 1cqwa.pdb
# 8: 1cr6a.pdb
# 9: 1ehya.pdb
#
# Length: 424
# Identity: 9/424 ( 2.1%) (Calculated as the percentage of conserved columns in the alignment.)
# Similarity: 14/424 ( 3.3%) (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps: 200/424 ( 47.2%) (Calculated as the percentage of columns with atleast one gap.)
#===========================================ALIGNMENT START=========================================
1a88a.pdb 1 ------------------------------GTVTT----SD----GTNIFYKDWGPR-DG 21
1a8q.pdb 1 ------------------------------PICTT----RD----GVEIFYKDWGQ---G 19
1a8s.pdb 1 ------------------------------TTFTT----RD----GTQIYYKDWGS---G 19
1b6g.pdb 1 MVNAIRTPDQRFSNL--D----QYPF--SPNYLDDLPGYPG-----LRAHYLDEGNSDAE 47
1brt.pdb 1 ------------------------------PFITV----GQENSTSIDLYYEDHGT---G 23
1c4xa.pdb 1 ------------------------TVEIIEKRFPS-----G----TLASHALVAGDP-QS 26
1cqwa.pdb 1 ---------------IGT----GFPF--DPHYVEV----LG-----ERMHYVDVGPR-DG 29
1cr6a.pdb 1 ------------------VPCNPNDV--SHGYVTV----KP----GIRLHFVEMGS---G 29
1ehya.pdb 1 ------------------AIRRPEDF--KHYEVQL----PD-----VKIHYVREGA---G 28
G
1a88a.pdb 22 LPVVFHHGWP-L--SADDWDNQMLFFLSHGYRVIAHDRRGHGRSDQPS-T---G-H---- 69
1a8q.pdb 20 RPVVFIHGWP-L--NGDAWQDQLKAVVDAGYRGIAHDRRGHGHSTPVW-D---G-Y---- 67
1a8s.pdb 20 QPIVFSHGWP-L--NADSWESQMIFLAAQGYRVIAHDRRGHGRSSQPW-S---G-N---- 67
1b6g.pdb 48 DVFLCLHGEP-T--WSYLYRKMIPVFAESGARVIAPDFFGFGKSDKPV-DE-ED-Y---- 97
1brt.pdb 24 QPVVLIHGFP-L--SGHSWERQSAALLDAGYRVITYDRRGFGQSSQPT-T---G-Y---- 71
1c4xa.pdb 27 PAVVLLHGAGPGAHAASNWRPIIPDLAE-NFFVVAPDLIGFGQSEYPE-TY--P-GHIMS 81
1cqwa.pdb 30 TPVLFLHGNP-T--SSYLWRNIIPHVAPSH-RCIAPDLIGMGKSDKP--D---LDY---- 76
1cr6a.pdb 30 PALCLCHGFP-E--SWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPP-EI-EE-Y---- 79
1ehya.pdb 29 PTLLLLHGWP-G--FWWEWSKVIGPLAEHY-DVIVPDLRGFGDSEKPDLNDLSK-Y---- 79
HG p w D G G S p
1a88a.pdb 70 DMDTYAADVAALTEALDLRGAVHIGHSTGGGEVARYVARAEPGRVAKAVLVSAV---PPV 126
1a8q.pdb 68 DFDTFADDLNDLLTDLDLRDVTLVAHSMGGGELARYVGRHGTGRLRSAVLLSAI---PPV 124
1a8s.pdb 68 DMDTYADDLAQLIEHLDLRDAVLFGFSTGGGEVARYIGRHGTARVAKAGLISAV---PPL 124
1b6g.pdb 98 TFEFHRNFLLALIERLDLRNITLVVQDWGGFLGLTLPMADP-SRFKRLIIMNAL--MTDP 154
1brt.pdb 72 DYDTFAADLNTVLETLDLQDAVLVGFSTGTGEVARYVSSYGTARIAKVAFLASL---EPF 128
1c4xa.pdb 82 WVGMRVEQILGLMNHFGIEKSHIVGNSMGGAVTLQLVVEAP-ERFDKVALMGSV---GAP 137
1cqwa.pdb 77 FFDDHVRYLDAFIEALGLEEVVLVIHDWGSALGFHWAKRNP-ERVKGIACMEFI---RPI 132
1cr6a.pdb 80 AMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYP-ERVRAVASLNTPFMPPDP 138
1ehya.pdb 80 SLDKAADDQAALLDALGIEKAYVVGHDFAAIVLHKFIRKYS-DRVIKAAIFDP--IQPD- 135
l R
1a88a.pdb 127 MVKSDT-------NPDGL--P--LEVFDEF------RAALAA-------N-RAQFYIDVP 161
1a8q.pdb 125 MIKSDK-------NPDGV--P--DEVFDAL------KNGVLT-------E-RSQFWKDTA 159
1a8s.pdb 125 MLKTEA-------NPGGL--P--MEVFDGI------RQASLA-------D-RSQLYKDLA 159
1b6g.pdb 155 ----VTQPAFSAFVT-QP--A---DGFTAW------KYDLVTP-SDL--R-LDQFMKRWA 194
1brt.pdb 129 LLKTDD-------NPDGAA-P--QEFFDGI------VAAVKA-------D-RYAFYTGFF 164
1c4xa.pdb 138 MN--------------AR-----PPELARL------LAFY-A-------DPRLTPYRELI 164
1cqwa.pdb 133 ----P-------TWDEWPEFA--RETFQAFRTADVGRELIIDQ-N--A-F-IEGVLPKCV 174
1cr6a.pdb 139 ----DV--SPMKVIR-SIP-V--FNYQLYFQEPGVAEAELEK-------N-MSRTFKSFF 180
1ehya.pdb 136 ---------------------FESWYSQFHQLDMAV-EVVGS-SR---EV-CKKYFKHFF 168
1a88a.pdb 162 S------------------------------GPFYGF-NR---EGATVSQGLIDHWWLQG 187
1a8q.pdb 160 E------------------------------GF-FSA-NR---PGNKVTQGNKDAFWYMA 184
1a8s.pdb 160 S------------------------------GPFFGF-NQ---PGAKSSAGMVDWFWLQG 185
1b6g.pdb 195 P---------------------------------------------TLTEAEASAYAAPF 209
1brt.pdb 165 N------------------------------DF-YNL-DENLG--TRISEEAVRNSWNTA 190
1c4xa.pdb 165 H------------------------------SF-VYDPEN---F--PGMEEIVKSRFEVA 188
1cqwa.pdb 175 V-----------------------------------R---------PLTEVEMDHYREPF 190
1cr6a.pdb 181 RASDETGFIAVHKATEIGGILVNTPEDPNLS--------------KITTEEEIEFYIQQF 226
1ehya.pdb 169 D------------------------------HW-SYRD-------ELLTEEELEVHVDNC 190
1a88a.pdb 188 MM-G-AANAHYECIAAFSE----T-----D--------FTDDL---KR-IDVPVLVAHGT 224
1a8q.pdb 185 MA-Q-TIEGGVRCVDAFGY----T-----D--------FTEDL---KK-FDIPTLVVHGD 221
1a8s.pdb 186 MA-A-GHKNAYDCIKAFSE----T-----D--------FTEDL---KK-IDVPTLVVHGD 222
1b6g.pdb 210 PDTS-YQAGVRKFPKMVAQ----RD-----Q-AIDI--STEAISFWQNDWNGQTFMAIGM 256
1brt.pdb 191 AS-G-GFFAAAAAPTT-WY----T-----D--------FRADI---PR-IDVPALILHGT 226
1c4xa.pdb 189 ND-PEVRRIQEVMFESMKA----G-----M---ESLVIPPATL---GR-LPHDVLVFHGR 231
1cqwa.pdb 191 LKPV-DREPLWRFPNEIP-------IAGEPANIVAL--VEAYMNWLHQ-SPVPKLLFWGT 239
1cr6a.pdb 227 KK---TG--FRGPLNWYRN----------TERNWKW--SCKGLGR--K-ILVPALMVTAE 266
1ehya.pdb 191 MK-PDNIHGGFNYYRANIRPDAAL-----W--------TD-LDHT--M-SDLPVTMIWGL 232
g
1a88a.pdb 225 DDQV---VPYADA-APKSAELLANAT-LKSYEGLPHGMLST--HPEVLNPDLLAFVKS-- 275
1a8q.pdb 222 DDQV---VPIDAT-GRKSAQIIPNAE-LKVYEGSSHGIAMVPGDKEKFNRDLLEFLNK-- 274
1a8s.pdb 223 ADQV---VPIEAS-GIASAALVKGST-LKIYSGAPHGLTDT--HKDQLNADLLAFIKG-- 273
1b6g.pdb 257 KDKL---LGPD-V-MYPMKALINGCPEPLEIADAGHFVQ-E--FGEQVAREALKHFAETE 308
1brt.pdb 227 GDRT---LPIENT-ARVFHKALPSAE-YVEVEGAPHGLLWT--HAEEVNTALLAFLAK-- 277
1c4xa.pdb 232 QDRI---VPLD-T-SLYLTKHLKHAE-LVVLDRCGHWAQLE--RWDAMGPMLMEHFRA-- 281
1cqwa.pdb 240 PGVL---IPPA-E-AARLAESLPNCK-TVDIGPGLHYLQED--NPDLIGSEIARWLPGLA 291
1cr6a.pdb 267 KDIV---LRPE-M-SKNMEKWIPFLK-RGHIEDCGHWTQIE--KPTEVNQILIKWLQTE- 317
1ehya.pdb 233 G---DTCVPYA-PLIEFVPKYYSNYT-METIEDCGHFLMVE--KPEIAIDRIKTAFR--- 282
H
1a88a.pdb ----
1a8q.pdb ----
1a8s.pdb ----
1b6g.pdb ----
1brt.pdb ----
1c4xa.pdb ----
1cqwa.pdb 292 SGLG 295
1cr6a.pdb ----
1ehya.pdb ----
#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue = Acidic,{D,E}
# Magenta = Basic,{K,R} and
# Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
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