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# Program: MUSTANG-Lite v0.1: A  Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Fri Jul 22 21:04:15 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/Lyase_8_NC.html
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#====================================
# Aligned_structures: 2
#   1: 1cb8a.pdb
#   2: 1egua.pdb
#
# Length:        783
# Identity:      124/783 ( 15.8%)  (Calculated as the percentage of conserved columns in the alignment.)
# Similarity:    124/783 ( 15.8%)  (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps:          171/783 ( 21.8%)  (Calculated as the percentage of columns with atleast one gap.)

#===========================================ALIGNMENT START=========================================


1cb8a.pdb               1  -GTAELIMKRVMLDLKKPL----------------RNMDKVAEKNLNTLQPDG-----SW   38
1egua.pdb               1  KDTYTDRLDDWNGIIA---GNQYYDSKNDQMAKLNQELEGKVADSLSSISSQ-ADRIYLW   56
                             T                                          L             W

1cb8a.pdb              39  KDVP-YKDDAMTNWLPNNHLLQLETIIQAYIEKDSHYYGDDKVFDQISKAFKYWYDS-D-   95
1egua.pdb              57  EKFSNYKTS----ANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYN  112
                                YK               LE          S YY D  V                 

1cb8a.pdb              96  ---PKSRNWWHNEIATPQALGEMLILMRYGKKPLDEALVHKLTERMKR---GEPE-----  144
1egua.pdb             113  SEKSIVGNWWDYEIGTPRAINNTLSLMKEY---FSDEEIKKYTDVIEKFVPDPE-HFRKT  168
                                  NWW  EI TP A    L LM             K T                 

1cb8a.pdb             145  -----KKTGANKTDIALHYFYRALLTSDEALLSFAVKELFYPVQFVHYEEGLQYDYSYLQ  199
1egua.pdb             169  TDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYID  228
                                K  G N  D         LL  D    S            V   EG   D SY  

1cb8a.pdb             200  HGPQLQISSYGAVFITGVLKLANYVRDTPYALSTEKLAIFSKYYRDSYLKAIRGSYMDFN  259
1egua.pdb             229  HTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDM  288
                           H        YG V I G   L      T       K          S             

1cb8a.pdb             260  VEGRGVSRPDIL--NKK---AEKKRLLVAKMIDLK-HTEEWADAIARTDS----------  303
1egua.pdb             289  SRGRSISRAN--SEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKN  346
                             GR  SR                                                    

1cb8a.pdb             304  ----TVAAGY---------------KIEPYHHQFWNGDYVQHLRP--AYSFNVRMVSKRT  342
1egua.pdb             347  LKTYKDI---SLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRT  403
                                                        Y   F   D            F     S RT

1cb8a.pdb             343  RRSESGNKENLLGRYLSDGATNIQLRG-PEY-YNIMPVWEWDKIPGITSRDYLTDRPLTK  400
1egua.pdb             404  LNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDA--KRADS-  460
                              E  NKEN  G Y SDG           Y     P     K PG T  D    R    

1cb8a.pdb             401  LWGEQGSNDF-AGGVSDGVYGASAYALDY---DSLQAKKAWFFFDKEIVCLGAGINSNAP  456
1egua.pdb             461  DTGKVLPSAFVGTSKLDDANATATMDF-TNWNQTLTAHKSWFMLKDKIAFLGSNIQNTST  519
                             G      F      D                 L A K WF     I  LG  I     

1cb8a.pdb             457  ENITTTLNQSWLNG----PVISTAGK-TGRGKITTFKAQGQFWLLH-----D-AIGYYFP  505
1egua.pdb             520  DTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPE--TQSVFLESSDSKKNIGYFFF  577
                               TT  Q  L       V                                  IGY F 

1cb8a.pdb             506  EGANLSLSTQSQKGNWFHINNSHSKDEVSGDVFKLWINHGARPENAQYAYIVLPGINKPE  565
1egua.pdb             578  KKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHK--QNGDSYGYMLIPNV-DRA  634
                                S S   QKG W  IN   S  EV          H        Y Y   P      

1cb8a.pdb             566  EIKKYNGTAP--KVLANTNQLQAVYHQQLDMVQAIFYTAGKLSVAGIEIETDKPCAVLIK  623
1egua.pdb             635  TFNQMIKEL-ESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQF-QVLKRGVYTIR  692
                                           N   LQ VY           Y               K     I 

1cb8a.pdb             624  HIN---GKQVIWAADPLQKEKTAVLSIRDLKTGKTNRVKIDFPQQEFAG-ATVEL-----  674
1egua.pdb             693  ---KEGDEYKIAYYNP-E------------------------------TQESAPDQEVFK  718
                                     I    P                                            

1cb8a.pdb                  ---     
1egua.pdb             719  KQH  721
                              


#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red         = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue        = Acidic,{D,E}
# Magenta     = Basic,{K,R} and
# Green       = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
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