################################################################################################ # Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm # Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey # Rundate: Sat Jul 23 19:02:32 2005 # Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/TyrKc.html ################################################################################################ #==================================== # Aligned_structures: 7 # 1: 1byga.pdb # 2: 1fgka.pdb # 3: 1ir3a.pdb # 4: 1qcfa.pdb # 5: 1vr2a.pdb # 6: 2src.pdb # 7: 3lck.pdb # # Length: 356 # Identity: 47/356 ( 13.2%) (Calculated as the percentage of conserved columns in the alignment.) # Similarity: 74/356 ( 20.8%) (Calculated as the percentage of semi-conserved columns in the alignment) # Gaps: 123/356 ( 34.6%) (Calculated as the percentage of columns with atleast one gap.) #===========================================ALIGNMENT START========================================= 1byga.pdb 1 ---------------------GWALNMKELKLLQTIGKGEFGDVMLGDYR---------G 30 1fgka.pdb 1 ---EL---PE-D--------PRWELPRDRLVLGKPLG-----QVVLAEAI-GL---PNRV 36 1ir3a.pdb 1 SSV-F---VP----------DEWEVSREKITLLRELGQGSFGMVYEGNAR-DIIKGE-AE 44 1qcfa.pdb 1 ------KPQ-KP-----WEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNK--------H 40 1vr2a.pdb 1 -----L--PY-DA-------SKWEFPRDRLKLGKPLGRGAFGQVIEADAF-GIDKTA-TC 43 2src.pdb 1 -------KP-QT---QGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNG--------T 41 3lck.pdb 1 ---------K-PWWE-----DEWEVPRETLKLVERLGAGQFGEVWMGYYNG--------H 37 We r l L lG V 1byga.pdb 31 NKVAVKCIKND-----AQAFLAEASVMTQ-LRHSNLVQLLGVIVE-E-GLYIVTEYMAKG 82 1fgka.pdb 37 TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG-PLYVIVEYASKG 95 1ir3a.pdb 45 TRVAVKTVNESASLRERIEFLNEASVMKG-FTCHHVVRLLGVVSKGQ-PTLVVMELMAHG 102 1qcfa.pdb 41 TKVAVKTMKPGSM--SVEAFLAEANVMKT-LQHDKLVKLHAVVTK-E-PIYIITEFMAKG 95 1vr2a.pdb 44 RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFG 103 2src.pdb 42 TRVAIKTLKPGTM--SPEAFLQEAQVMKK-LRHEKLVQLYAVVSE-E-PIYIVTEYMSKG 96 3lck.pdb 38 TKVAVKSLKQGSM--SPDAFLAEANLMKQ-LQHQRLVRLYAVVTQ-E-PIYIITEYMENG 92 VAvK k E m h v L p E G 1byga.pdb 83 SLVDYLRSRGR------------------SVLGGDCLLKFSLDVCEAMEYLEGNNFVHRD 124 1fgka.pdb 96 NLREYLQARR----------PPE------EQLSSKDLVSCAYQVARGMEYLASKKCIHRD 139 1ir3a.pdb 103 DLKSYLRSLR-PEAENNPGR---------PPPTLQEMIQMAAEIADGMAYLNAKKFVHRD 152 1qcfa.pdb 96 SLLDFLKSDEG------------------SKQPLPKLIDFSAQIAEGMAFIEQRNYIHRD 137 1vr2a.pdb 104 NLSTYLRSKR----------N--EFVPYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRD 151 2src.pdb 97 SLLDFLKGETG------------------KYLRLPQLVDMAAQIASGMAYVERMNYVHRD 138 3lck.pdb 93 SLVDFLKTPSG------------------IKLTINKLLDMAAQIAEGMAFIEERNYIHRD 134 L L l a gM HRD 1byga.pdb 125 LAARNVLVSEDNVAKVSDFGL-----------------------L-----PVKWTAPEAL 156 1fgka.pdb 140 LAARNVLVTEDNVMKIADFG----LAR--DI---HHI-DYYKK-TTNGRLPVKWMAPEAL 188 1ir3a.pdb 153 LAARNCMVAHDFTVKIGDFG---MTRDI-ETD-R--K-GGKGL-L-----PVRWMAPESL 198 1qcfa.pdb 138 LRAANILVSASLVCKIADFG-LARVIE-DNE----YT-AREGAKF-----PIKWTAPEAI 185 1vr2a.pdb 152 LAARNILLSEKNVVKICDF---------------------------DARLPLKWMAPETI 184 2src.pdb 139 LRAANILVGENLVCKVADFG-LARLIE-DNE----YT-ARQGAKF-----PIKWTAPEAA 186 3lck.pdb 135 LRAANILVSDTLSCKIADFG---LARLI-EDNE---TAREGAK-F-----PIKWTAPEAI 181 L A N lv K DF P kW APE 1byga.pdb 157 REKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLK--DVVPRVEKGYKMDAPDGCPPAVY 214 1fgka.pdb 189 FDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVE--ELFKLLKEGHRMDKPSNCTNELY 246 1ir3a.pdb 199 KDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNE--QVLKFVMDGGYLDQPDNCPERVT 256 1qcfa.pdb 186 NFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNP--EVIRALERGYRMPRPENCPEELY 243 1vr2a.pdb 185 FDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEF-CRRLKEGTRMRAPDYTTPEMY 243 2src.pdb 187 LYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNR--EVLDQVERGYRMPCPPECPESLH 244 3lck.pdb 182 NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP--EVIQNLERGYRMVRPDNCPEELY 239 t SDvWSFG lL Ei g PYpg G m P c 1byga.pdb 215 EVMKNCWHLDAAMRPSFLQLREQLEHIK------------T---HEL--------- 246 1fgka.pdb 247 MMMRDCWHAVPSQRPTFKQLVEDLDRIV------------A---LTS--------- 278 1ir3a.pdb 257 DLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENK------------ 300 1qcfa.pdb 244 NIMMRCWKNRPEERPTFEYIQSVLDDFY------------T---AT-ESQEEIP-- 281 1vr2a.pdb 244 QTMLDCWHGEPSQRPTFSELVEHLGNLL------------Q---ANA--------- 275 2src.pdb 245 DLMCQCWRKEPEERPTFEYLQAFLEDYF------------T---ST-EPQQPGENL 284 3lck.pdb 240 QLMRLCWKERPEDRPTFDYLRSVLEDFF------------T---AT---------- 270 M CW p RPtF L #=========================================ALIGNMENT END============================================= #LEGEND: # # Colours indicate the chemical nature of the amino acid; # Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W} # Blue = Acidic,{D,E} # Magenta = Basic,{K,R} and # Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}. # # The "markup row" below each stretch of the multiple alignment is used to mark completely conserved # residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment. # ################################################EOF#################################################