################################################################################################
# Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Sat Jul 23 17:13:53 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/aldosered.html
################################################################################################
#====================================
# Aligned_structures: 7
# 1: 1a80.pdb
# 2: 1ads.pdb
# 3: 1afsa.pdb
# 4: 1ah4.pdb
# 5: 1frb.pdb
# 6: 1qrqa.pdb
# 7: 2alr.pdb
#
# Length: 403
# Identity: 24/403 ( 6.0%) (Calculated as the percentage of conserved columns in the alignment.)
# Similarity: 62/403 ( 15.4%) (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps: 147/403 ( 36.5%) (Calculated as the percentage of columns with atleast one gap.)
#===========================================ALIGNMENT START=========================================
1a80.pdb 1 ----TV--PSIV-LNDGNSIPQLGYGVFKV-----PPADTQRAVEEALEVGYRHIDTAAI 48
1ads.pdb 1 -------ASRLL-LNNGAKMPILGLGTWK-----SPPGQVTEAVKVAIDVGYRHIDCAHV 47
1afsa.pdb 1 MDSI-S--LRVA-LNDGNFIPVLGFGTTV--PEKVAKDEVIKATKIAIDNGFRHFDSAYL 54
1ah4.pdb 1 --------SHLV-LYTGAKMPILGLGTWK-----SPPGKVTEAVKVAIDLGYRHIDCAHV 46
1frb.pdb 1 -------ATFVE-LSTKAKMPIVGLGTWK-----SPPNQVKEAVKAAIDAGYRHIDCAYA 47
1qrqa.pdb 1 ------LQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEV 54
2alr.pdb 1 ----AA--SCVL-LHTGQKMPLIGLGTWK-----SEPGQVKAAVKYALSVGYRHIDCAAI 48
l g p G Gt a A G rh D A
1a80.pdb 49 Y---GNEEGVGAAIAAS-G----IARDDLFITTKLWND--------RHDGDEPAAAIAES 92
1ads.pdb 48 Y---QNENEVGVAIQEK-LREQVVKREELFIVSKLWCT--------YHEKGLVKGACQKT 95
1afsa.pdb 55 Y---EVEEEVGQAIRSK-IEDGTVKREDIFYTSKLWST--------FHRPELVRTCLEKT 102
1ah4.pdb 47 Y---QNENEVGLGLQEK-LQGQVVKREDLFIVSKLWCT--------DHEKNLVKGACQTT 94
1frb.pdb 48 Y---CNENEVGEAIQEK-IKEKAVQREDLFIVSKLWPT--------CFEKKLLKEAFQKT 95
1qrqa.pdb 55 YAAGKAEVVLGNIIKKK-G----WRRSSLVITTKIFW-GGKAETERGLSRKHIIEGLKAS 108
2alr.pdb 49 Y---GNEPEIGEALKEDVGPGKAVPREELFVTSKLWNT--------KHHPEDVEPALRKT 97
Y E G R lf Klw
1a80.pdb 93 LAKLALDQVDLYLVHWPT-------------------PAAD-NYVHAWEKMIELRAAGLT 132
1ads.pdb 96 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPS-D-TNILDTWAAMEELVDEGLV 153
1afsa.pdb 103 LKSTQLDYVDLYIIHFPMALQPGDIFFPRDEHGKLLFE-T-VDICDTWEAMEKCKDAGLA 160
1ah4.pdb 95 LRDLKLDYLDLYLIHWPTGFKPGKDPFPLDGDGNVVPD-E-SDFVETWEAMEELVDEGLV 152
1frb.pdb 96 LTDLKLDYLDLYLIHWPQGLQPGKELFPKDDQGRILTS-K-TTFLEAWEGMEELVDQGLV 153
1qrqa.pdb 109 LERLQLEYVDVVFANRPD-------------------P-N-TPMEETVRAMTHVINQGMA 147
2alr.pdb 98 LADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYD-S-THYKETWKALEALVAKGLV 155
L l L y Dly h P w m Gl
1a80.pdb 133 RSIGVSNHLVPHLERIVAA------TGVVPAVNQIELHPAYQQ--REIT-DWAAAHDVKI 183
1ads.pdb 154 KAIGISNFNHLQVEMILNKPG----LKYKPAVNQIECHPYLTQ--EKLI-QYCQSKGIVV 206
1afsa.pdb 161 KSIGVSNFNCRQLERILNKPG----LKYKPVCNQVECHLYLNQ--SKML-DYCKSKDIIL 213
1ah4.pdb 153 KAIGVSNFNHLQVEKILNKPG----LKYKPAVNQIEVHPYLTQ--EKLI-EYCKSKGIVV 205
1frb.pdb 154 KALGVSNFNHFQIERLLNKPG----LKHKPVTNQVECHPYLTQ--EKLI-QYCHSKGISV 206
1qrqa.pdb 148 MYWGTSRWSSMEIMEAYSV--ARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGA 205
2alr.pdb 156 QALGLSNFNSRQIDDILSV------ASVRPAVLQVECHPYLAQ--NELI-AHCQARGLEV 206
G Sn P Q E H q
1a80.pdb 184 ESWGPLGQGK---------Y-------------------------DLFG----------A 199
1ads.pdb 207 TAYSPLGSPDR-PWAKPEDP-------------------------SLLE----------D 230
1afsa.pdb 214 VSYCTLGSSRDKTWVDQKSP-------------------------VLLD----------D 238
1ah4.pdb 206 TAYSPLGSPDR-PWAKPEDP-------------------------SLLE----------D 229
1frb.pdb 207 TAYSPLGSPDR-PSAKPEDP-------------------------SLLE----------D 230
1qrqa.pdb 206 MTWSPLACG-----------IVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKL 254
2alr.pdb 207 TAYSPLG--------------------------------------VLLE----------E 218
pLg l
1a80.pdb 200 EPVTAAAAAHGKTPAQAVLRWHLQKG-F-VVFPKSVRRERLEENLDVFDF-D-LTDTEIA 255
1ads.pdb 231 PRIKAIAAKHNKTTAQVLIRFPMQRN-L-VVIPKSVTPERIAENFKVFDF-E-LSSQDMT 286
1afsa.pdb 239 PVLCAIAKKYKQTPALVALRYQLQRG-V-VPLIRSFNAKRIKELTQVFEF-Q-LASEDMK 294
1ah4.pdb 230 PRIKAIAAKYNKTTAQVLIRFPMQRN-L-IVIPKSVTPERIAENFQVFDF-E-LSPEDMN 285
1frb.pdb 231 PKIKEIAAKHEKTSAQVLIRFHIQRN-V-VVIPKSVTPSRIQENIQVFDF-Q-LSDEEMA 286
1qrqa.pdb 255 KELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNAEQLMENIGAIQVLPKLSSSIVH 314
2alr.pdb 219 PVVLALAEKYGRSPAQILLRWQVQRK-V-ICIPKSITPSRILQNIKVFDF-T-FSPEEMK 274
a A t aq r q s r en vf f l
1a80.pdb 256 AIDAMDPGDGSGRV---------S----------AHPDEV--D 277
1ads.pdb 287 TLLSYNRNWRVCAL---------LSCTSHKDYPF----HEEF- 315
1afsa.pdb 295 ALDGLNRNFRYNNA---------KYFDDHPNHPF--------- 319
1ah4.pdb 286 TLLSYNRNWRVCAL---------MSCASHKDYPF----HEEY- 314
1frb.pdb 287 TILSFNRNWRACLL---------PETVNMEEYPY----DAE-- 314
1qrqa.pdb 315 EIDSIL----GNKP---------Y------------------- 325
2alr.pdb 275 QLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPF----NDPY- 312
#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue = Acidic,{D,E}
# Magenta = Basic,{K,R} and
# Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
################################################EOF#################################################