################################################################################################
# Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Fri Aug 12 22:06:08 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/MUSTANG_HOMSTRAD/results/grs.html
################################################################################################
#====================================
# Aligned_structures: 11
# 1: 1ebda.pdb
# 2: 1gera.pdb
# 3: 1lpfa.pdb
# 4: 1lvl.pdb
# 5: 1ndaa.pdb
# 6: 1npx.pdb
# 7: 1ojt.pdb
# 8: 1trb.pdb
# 9: 2tpra.pdb
# 10: 3grs.pdb
# 11: 3lada.pdb
#
# Length: 598
# Identity: 12/598 ( 2.0%) (Calculated as the percentage of conserved columns in the alignment.)
# Similarity: 28/598 ( 4.7%) (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps: 333/598 ( 55.7%) (Calculated as the percentage of columns with atleast one gap.)
#===========================================ALIGNMENT START=========================================
1ebda.pdb 1 ----AIETETLVVGAGPGGYVAAIRAAQ-L-G-QKVTIVEKG---------------N-L 37
1gera.pdb 1 -----KHYDYIAIGGGSGGIASINRAAM-Y-G-QKCALIEAK---------------E-L 36
1lpfa.pdb 1 ----SQKFDVVVIGAGPGGYVAAIRAAQ-L-G-LKTACIEKYAGKAGAT--------A-L 44
1lvl.pdb 1 --QQTIQTTLLIIGGGPGGYVAAIRAGQ-L-G-IPTVLVEGQ---------------A-L 39
1ndaa.pdb 1 ------IFDLVVIGAGSGGLEAAWNAATLY-K-KRVAVIDVQ------MVHGPPFFSA-L 45
1npx.pdb 1 M-------KVIVLGSSHGGYEAVEELLN-LHPDAEIQWYEKG---------------DFI 37
1ojt.pdb 1 -GSADAEYDVVVLGGGPGGYSAAFAAAD-E-G-LKVAIVERY------K--------T-L 41
1trb.pdb 1 --GTTKHSKLLILGSGPAGYTAAVYAAR-A-N-LQPVLITGM---------------E-K 39
2tpra.pdb 1 ----SRAYDLVVIGAGSGGLEAGWNAASLH-K-KRVAVIDLQ------KHHGPPHYAA-L 47
3grs.pdb 1 ----VASYDYLVIGGGSGGLASARRAAE-L-G-ARAAVVESH---------------K-L 37
3lada.pdb 1 ----SQKFDVIVIGAGPGGYVAAIKSAQ-L-G-LKTALIEKYKGKEGKT--------A-L 44
G g gG
1ebda.pdb 38 G-GVCLNVGCIPS-----KA-LI-S---ASHRYEQA-K-HSE---EMGIKA-E-NVTIDF 79
1gera.pdb 37 G-GTCVNVGCVPK-----KV-MW-H---AAQIREAIHM-YGP---DYGFDT-T-INKFNW 79
1lpfa.pdb 45 G-GTCLNVGCIPS-----KA-LL-D---SSYKYHEA-AEAFK---VHGIEA-A-GVTIDV 87
1lvl.pdb 40 G-GTCLNIGCIPS-----KA-LI-H---VAEQFHQA-S-RFTEPSPLGISV-A-SPRLDI 84
1ndaa.pdb 46 G-GTCVNVGCVPK-----KL-MV-T---GAQYMEHL-R-ESA---GFGWEFDRTTLRAEW 89
1npx.pdb 38 SFLSCGM-----Q-----LY-LE-GKVK-------------------------------- 53
1ojt.pdb 42 G-GVCLNVGCIPS-----KA-LL-H---NAAVIDEV-R-HLA---ANGIKY-P-EPELDI 83
1trb.pdb 40 G-GQLTT-----TTEVENW-PGDPNDL--------------------------------- 59
2tpra.pdb 48 G-GTCVNVGCVPK-----KL-MV-T---GANYMDTI-R-ESA---GFGWELDRESVRPNW 91
3grs.pdb 38 G-GTCVNVGCVPK-----KV-MW-N---TAVHSEFM-H-DHA---DYGFPS-C-EGKFNW 79
3lada.pdb 45 G-GTCLNVGCIPS-----KA-LL-D---SSYKFHEA-HESFK---LHGIST-G-EVAIDV 87
g g c
1ebda.pdb 80 AKVQEWKASVVKKLTG-GVEGLLKGNK-VEIV-KGEAYFVD-A--NTVRVVN-------- 125
1gera.pdb 80 ETLIASRTAYIDRIHT-SYENVLGKNN-VDVI-KGFARFVD-A--KTLEV---------- 123
1lpfa.pdb 88 PAMVARKANIVKNLTG-GIATLFKANG-VTSF-EGHGKLLA-N--KQVEVTG-------- 133
1lvl.pdb 85 GQSVAWKDGIVDRLTT-GVAALLKKHG-VKVV-HGWAKVLD-G--KQVEVD--------- 129
1ndaa.pdb 90 KKLIAVKDEAVLNINK-SYEEMFRDTEGLEFF-LGWGSLES-K--NVVNVRE-------- 136
1npx.pdb 54 ---------DVNSVRYM-TGEKMESRG-VNVFSNTEITAIQ-PKEHQVTVKD-------- 93
1ojt.pdb 84 DMLRAYKDGVVSRLTG-GLAGMAKSRK-VDVI-QGDGQFLD-P--HHLEVSLTAGDAYEQ 137
1trb.pdb 60 ---------TGPLLME-RMHEHATKFE-TEII-FDHINKVD-LQNRPFRLNG-------- 98
2tpra.pdb 92 KALIAAKNKAVSGIND-SYEGMFADTEGLTFH-QGFGALQD-N--HTVLVRE-------- 138
3grs.pdb 80 RVIKEKRDAYVSRLNA-IYQNNLTKSH-IEII-RGHAAFTSDP-KPTIEV---------- 125
3lada.pdb 88 PTMIARKDQIVRNLTG-GVASLIKANG-VTLF-EGHGKLLA-G--KKVEVTA-------- 133
v
1ebda.pdb 126 --G----DS-AQTYTFKNAIIATGSRPIELP--N-FK---FSNRILDST---GALNLG-- 167
1gera.pdb 124 ---------NGETITADHILIATGGRPSHPD--I---P--GVEYGIDSD---GFFALP-- 162
1lpfa.pdb 134 --L----DGATQVLEAENVIIASGSAPVEIP--P-AP--LTDDIIVDST---GALEFQ-- 177
1lvl.pdb 130 ----------GQRIQCEHLLLATGSSSVELP--M-LP---LGGPVISST---EALAPK-- 168
1ndaa.pdb 137 --SADPASAVKERLETENILLASGSWPHMPN--I---P--GIEHCISSN---EAFYLP-- 182
1npx.pdb 94 --L---VSGEERVENYDKLIISPGAVPFELD--I-PGK--DLDNIYLMRGRQWAIKLKQK 143
1ojt.pdb 138 AAP----TGEKKIVAFKNCIIAAGSRVTKLP--F-IP---EDPRIIDSS---GALALK-- 182
1trb.pdb 99 ---------DNGEYTCDALIIATGASARYLGLPS-EEAF-KGRGVSA-C---ATSDGFFY 143
2tpra.pdb 139 --SADPNSAVLETLDTEYILLATGSWPQHLG--I---E--GDDLCITSN---EAFYLD-- 184
3grs.pdb 126 ---------SGKKYTAPHILIATGGMPSTPH--ESQIP--GASLGITSD---GFFQLE-- 167
3lada.pdb 134 --A----DGSSQVLDTENVILASGSKPVEIP--P-AP--VDQDVIVDST---GALDFQ-- 177
a G
1ebda.pdb 168 ----EVPKSLVVIGGGYIGIELGTAYANFG---TKVTILEGAGEILS-GFEKQMAAIIKK 219
1gera.pdb 163 ----ALPERVAVVGAGYIAVELAGVINGLG---AKTHLFVRKHAPLR-SFDPMISETLVE 214
1lpfa.pdb 178 ----AVPKKLGVIGAGVIGLELGSVWARLG---AEVTVLEALDKFLP-AADEQIAKEALK 229
1lvl.pdb 169 ----ALPQHLVVVGGGYIGLELGIAYRKLG---AQVSVVEARERILP-TYDSELTAPVAE 220
1ndaa.pdb 183 ----EPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILR-GFDHTLREELTK 237
1npx.pdb 144 TVDPE-VNNVVVIGSGYIGIEAAEAFAKAG---KKVTVIDILDRPLGVYLDKEFTDVLTE 199
1ojt.pdb 183 ----EVPGKLLIIGGGIIGLEMGTVYSTLG---SRLDVVEMMDGLMQ-GADRDLVKVWQK 234
1trb.pdb 144 R---N--QKVAVIGGGNTAVEEALYLSNIA---SEVHLIHRRDGFR---A-EKILIKRLM 191
2tpra.pdb 185 ----EAPKRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILR-GFDSELRKQLTE 239
3grs.pdb 168 ----ELPGRSVIVGAGYIAVEMAGILSALG---SKTSLMIRHDKVLR-SFDSMISTNCTE 219
3lada.pdb 178 ----NVPGKLGVIGAGVIGLELGSVWARLG---AEVTVLEAMDKFLP-AVDEQVAKEAQK 229
G G i E
1ebda.pdb 220 RLK-KKGVEVVTNALAKGAEERED-GVTVTYEAN------G--ETKTIDADYVLVTVGRR 269
1gera.pdb 215 VMN-AEGPQLHTNAIPKAVVKNTDGSLTLELE-----------DGRSETVDCLIWAIGRE 262
1lpfa.pdb 230 VLT-KQGLNIRLGARVTASEVKKK-QVTVTFTDA------N--GEQAATFDKLIVAVGRR 279
1lvl.pdb 221 SLK-KLGIALHLGHSVEGYEN-----GCLLANDG---K--G--GQLRLEADRVLVAVGRR 267
1ndaa.pdb 238 QLT-ANGIQILTKENPAKVELNADGSKSVTFE-----------SGKKMDFDLVMMAIGRS 285
1npx.pdb 200 EME-ANNITIATGETVERYEGD-GRVQKVVTD-----------K-NAYDADLVVVAVGVR 245
1ojt.pdb 235 QNE-YRFDNIMVNTKTVAVEPKED-GVYVTFEGA------NAP-KEPQRYDAVLVAAGRA 285
1trb.pdb 192 DKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQ-NS-DN--I-ESLDVAGLFVAIGHS 246
2tpra.pdb 240 QLR-ANGINVRTHENPAKVTKNADGTRHVVFE-----------SGAEADYDVVMLAIGRV 287
3grs.pdb 220 ELE-NAGVEVLKFSQVKEVKKTLSGLEVSMVT-AVPGRLPV--MTMIPDVDCLLWAIGRV 275
3lada.pdb 230 ILT-KQGLKILLGARVTGTEVKNK-QVTVKFVDA------E--GEKSQAFDKLIVAVGRR 279
d a G
1ebda.pdb 270 PNTDELGLEQIGIKMTNRGLIEVDQ-----QCRTSVPNIFAIGDIVPG-----------P 313
1gera.pdb 263 PANDNINLEAAGVKTNEKGYIVVDK-----YQNTNIEGIYAVGDNTGA-----------V 306
1lpfa.pdb 280 PVTTDLLAADSGVTLDERGFIYVDD-----HCKTSVPGVFAIGDVVRG-----------A 323
1lvl.pdb 268 PRTKGFNLECLDLKMN-GAAIAIDE-----RCQTSMHNVWAIGDVAGE-----------P 310
1ndaa.pdb 286 PRTKDLQLQNAGVMIK-NGGVQVDE-----YSRTNVSNIYAIGDVTNR-----------V 328
1npx.pdb 246 PNTAWLK-G--TLELHPNGLIKTDE-----YMRTSEPDVFAVGDATLIKYNPADTEV-NI 296
1ojt.pdb 286 PNGKLISAEKAGVAVTDRGFIEVDK-----QMRTNVPHIYAIGDIVGQ-----------P 329
1trb.pdb 247 PNTAIFE-G--QLELE-NGYIKVQSGIHGNATQTSIPGVFAAGDVMD----------HIY 292
2tpra.pdb 288 PRSQTLQLEKAGVEVAKNGAIKVDA-----YSKTNVDNIYAIGDVTDR-----------V 331
3grs.pdb 276 PNTKDLSLNKLGIQTDDKGHIIVDE-----FQNTNVKGIYAVGDVCGK-----------A 319
3lada.pdb 280 PVTTDLLAADSGVTLDERGFIYVDD-----YCATSVPGVYAIGDVVRG-----------A 323
P g i d T A GD
1ebda.pdb 314 ALAHKASYEGKVAAEAIAGHP--SAVDYVAIPAVVFSD-PECASVGYFEQQAKDEGI--D 368
1gera.pdb 307 ELTPVAVAAGRRLSERLFNNKPDEHLDYSNIPTVVFSH-PPIGTVGLTEPQAREQYGDDQ 365
1lpfa.pdb 324 MLAHKASEEGVMVAERIAGHK--AQMNYDLIPSVIYTH-PEIAWVGKTEQTLKAEGV--E 378
1lvl.pdb 311 MLAHRAMAQGEMVAEIIAGKA--RRFEPAAIAAVCFTD-PEVVVVGKTPEQASQQGL--D 365
1ndaa.pdb 329 MLTPVAINEAAALVDTVFGTNP-RKTDHTRVASAVFSI-PPIGTCGLIEEVASKRYE--V 384
1npx.pdb 297 ALATNARKQGRFAVKNLEEP-V-KPFPGVQGSSGLAVFDYKFASTGINEVMAQKLGK--E 352
1ojt.pdb 330 MLAHKAVHEGHVAAENCAGHK--AYFDARVIPGVAYTS-PEVAWVGETELSAKASAR--K 384
1trb.pdb 293 RQAITSAGTGCMAALDAE------------------------------------------ 310
2tpra.pdb 332 MLTPVAINEGAAFVDTVFANKP-RATDHTKVACAVFSI-PPMGVCGYVEEDAAKKYD--Q 387
3grs.pdb 320 LLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSH-PPIGTVGLTEDEAIHKYGIEN 378
3lada.pdb 324 MLAHKASEEGVVVAERIAGHK--AQMNYDLIPAVIYTH-PEIAGVGKTEQALKAEGV--A 378
l a g
1ebda.pdb 369 VIAAKFPFAANGRALALND--TDGFLKLVVRKEDGVIIGAQIIG-PNASDMIAELGLAIE 425
1gera.pdb 366 VKVYKSSF-TAMYTAVTTH-RQPCRMKLVCVGSEEKIVGIHGIG-FGMDEMLQGFAVALK 422
1lpfa.pdb 379 VNVGTFPFTTSGRAMAAND--TTGLVKVIADAKTDRVLGVHVIG-PSAAELVQQGAIGME 435
1lvl.pdb 366 CIVAQFPFAANGRAMSLES--KSGFVRVVARRDNHLILGWQAVG-VAVSELSTAFAQSLE 422
1ndaa.pdb 385 VAVYLSSF-TPLMHNISGSKYKTFVAKIITNHSDGTVLGVHLLG-DNAPEIIQGVGICLK 442
1npx.pdb 353 TKAVTVVE-DYL-MDFNPD-KQKAWFKLVYDPETTQILGAQLMSKADLTANINAISLAIQ 409
1ojt.pdb 385 ITKANFPWAASGRAIANGC--DKPFTKLIFDAETGRIIGGGIVG-PNGGDMIGEVCLAIE 441
1trb.pdb 311 ---------------------------------------------------------RYL 313
2tpra.pdb 388 VAVYESSF-TPLMHNISGSTYKKFMVRIVTNHADGEVLGVHMLG-DSSPEIIQSVAICLK 445
3grs.pdb 379 VKTYSTSF-TPMYHAVTKR-KTKCVMKMVCANKEEKVVGIHMQG-LGCDEMLQGFAVAVK 435
3lada.pdb 379 INVGVFPFAASGRAMAAND--TAGFVKVIADAKTDRVLGVHVIG-PSAAELVQQGAIAME 435
1ebda.pdb 426 AGMTAEDIALTIHAHP-------TLGEIAMEA------AEVAL--------------- 455
1gera.pdb 423 MGATKKDFDNTVAIHP-------TAAEEFVTM------R------------------- 448
1lpfa.pdb 436 FGTSAEDLGMMVFSHP-------TLSEALHEA------ALAVNGHAIHI----A---- 472
1lvl.pdb 423 MGACLEDVAGTIHAHP-------TLGEAVQEA------ALRALGHALHI--------- 458
1ndaa.pdb 443 LNAKISDFYNTIGVHP-------TSAEELCSM------RTPS-YYYVKGEKME----- 481
1npx.pdb 410 AKMTIEDLAYADFFFQPAFDKPWNIINTAALEAVKQER-------------------- 447
1ojt.pdb 442 MGCDAADIGKTIHPHP-------TLGESIGMA------AEVALGTCTDL----PPQKK 482
1trb.pdb 314 DGL------------------------------------------------------- 316
2tpra.pdb 446 MGAKISDVYNTIGVHP-------TSAEELCSM------RTPA-YFYEKGKR------- 482
3grs.pdb 436 MGATKADFDNTVAIHP-------TSSEELVTL------R------------------- 461
3lada.pdb 436 FGTSAEDLGMMVFAHP-------ALSEALHEA------ALAVSGHAIHV----A---- 472
#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue = Acidic,{D,E}
# Magenta = Basic,{K,R} and
# Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
################################################EOF#################################################