################################################################################################ # Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm # Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey # Rundate: Sat Jul 23 02:32:29 2005 # Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/hexokinase.html ################################################################################################ #==================================== # Aligned_structures: 3 # 1: 1bdg.pdb # 2: 1hkca1.pdb # 3: 1hkca2.pdb # # Length: 461 # Identity: 146/461 ( 31.7%) (Calculated as the percentage of conserved columns in the alignment.) # Similarity: 315/461 ( 68.3%) (Calculated as the percentage of semi-conserved columns in the alignment) # Gaps: 30/461 ( 6.5%) (Calculated as the percentage of columns with atleast one gap.) #===========================================ALIGNMENT START========================================= 1bdg.pdb 1 FSDQQLFEKVVEILKPFDLSVVDYEEICDRMGESMRLGLQKSTNEKSSIKMFPSYVTKTP 60 1hkca1.pdb 1 -----QHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTP 55 1hkca2.pdb 1 --D-DQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIP 57 q ki e L f Ls l ei Rmr eM lGL k tn a vKMlPsfVr tP 1bdg.pdb 61 NGTETGNFLALDLGGTNYRVLSVTLEGG--KSPRIQERTYCIPAEKMSGSGTELFKYIAE 118 1hkca1.pdb 56 DGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVS 115 1hkca2.pdb 58 DGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAE 117 dGtE GdFlALDLGGtnfRvL V g v m Y iP eim GsG eLFdhiae 1bdg.pdb 119 TLADFLENNGMKDKKFDLGFTFSFPCVQKGLTHATLVRWTKGFSADGVEGHNVAELLQTE 178 1hkca1.pdb 116 CISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDA 175 1hkca2.pdb 118 CLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKA 177 cl DFle giKdkk plGFTFSFPCqQ ld aiLitWTKgFkA gveGhdVv LL a 1bdg.pdb 179 LDKRELNVKC-VAVVNDTVGTLASCALEDPKCAVGLIVGTGTNVAYIEDSSKVELMDGVK 237 1hkca1.pdb 176 IKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVE-GD 234 1hkca2.pdb 178 IKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVE-GD 236 ikkRe d VAVVNDTVGTmmtCayedp CeVGLIvGTGtNacYmEe velve gd 1bdg.pdb 238 EPEVVINTEWGAFGEKGELDCWRTQFDKSMDIDSLHPGKQLYEKMVSGMYLGELVRHIIV 297 1hkca1.pdb 235 QGQMCINMEWGAFGDNGCLDDIRTHYDRLVNEYSLNAGKQRYEKMISGMYLGEIVRNILI 294 1hkca2.pdb 237 EGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILV 296 eg mcINtEWGAFGd G LddiRT fDr d SLnpGKQlyEKMvSGMYLGElVR Ilv 1bdg.pdb 298 YLVEQKILFRGDLPERLKVRNSLLTRYLTDVERDPAHL-LYNTHYMLTDDLHVPVVEPID 356 1hkca1.pdb 295 DFTKKGFLFRGQISETLKTRGIFETKFLSQIES-DR-LALLQVRAILQQL-G-LNSTCDD 350 1hkca2.pdb 297 KMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKN-K-EGLHNAKEILTRL-G-VEPSDDD 352 k g LFrG i e LktRg f T ls iE l L n iLt l g dD 1bdg.pdb 357 NRIVRYACEMVVKRAAYLAGAGIACILRRINR-------SEVTVGVDGSLYKFHPKFCER 409 1hkca1.pdb 351 SILVKTVCGVVSRRAAQLCGAGMAAVVDKIR-ENRGLDRLNVTVGVDGTLYKLHPHFSRI 409 1hkca2.pdb 353 CVSVQHVCTIVSFRSANLVAATLGAILNRLR-DNKGTPRLRTTVGVDGSLYKTHPQYSRR 411 V vC Vs RaA L gAg aail rir l vTVGVDGsLYK HP fsrr 1bdg.pdb 410 MTDMVDKLKPKNTRFCLRLSEDGSGKGAAAIAASC------ 444 1hkca1.pdb 410 MHQTVKELS-PKCNVSFLLSEDGSGKGAALITAVGVRLRTE 449 1hkca2.pdb 412 FHKTLRRLV-PDSDVRFLLSESGSGKGAAMVTAVAYRLAE- 450 mh tv L p v flLSEdGSGKGAA itAv #=========================================ALIGNMENT END============================================= #LEGEND: # # Colours indicate the chemical nature of the amino acid; # Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W} # Blue = Acidic,{D,E} # Magenta = Basic,{K,R} and # Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}. # # The "markup row" below each stretch of the multiple alignment is used to mark completely conserved # residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment. # ################################################EOF#################################################