################################################################################################ # Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm # Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey # Rundate: Sat Jul 23 23:42:46 2005 # Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/ltn.html ################################################################################################ #==================================== # Aligned_structures: 12 # 1: 1avba.pdb # 2: 1lec.pdb # 3: 1len.pdb # 4: 1lgc.pdb # 5: 1loe.pdb # 6: 1lte.pdb # 7: 1lu1.pdb # 8: 1sbf.pdb # 9: 1wbla.pdb # 10: 2ltn.pdb # 11: 2pela.pdb # 12: 5cna.pdb # # Length: 290 # Identity: 25/290 ( 8.6%) (Calculated as the percentage of conserved columns in the alignment.) # Similarity: 52/290 ( 17.9%) (Calculated as the percentage of semi-conserved columns in the alignment) # Gaps: 86/290 ( 29.7%) (Calculated as the percentage of columns with atleast one gap.) #===========================================ALIGNMENT START========================================= 1avba.pdb 1 ----SNDASFNVETFN----K--TNLILQGDATVS-SEGHLLLTNVK---GNEEDSMGRA 46 1lec.pdb 1 -----NTVNFTYPDFWSYSLKNGTEITFLGDATRI-PG-ALQLTKTDANGNPVRSSAGQA 53 1len.pdb 1 ----TETTSFSITKFS--PDQ--QNLIFQGDGYTT-KG-KLTLT-K-----AVKSTVGRA 44 1lgc.pdb 1 ----TETTSFSITKFG--PDQ--PNLIFQGDGYTT-KE-RLTLT-K-----AVRNTVGRA 44 1loe.pdb 1 ----TETTSFSITKFG--PDQ--QNLIFQGDGYTT-KE-RLTLT-K-----AVRNTVGRA 44 1lte.pdb 1 ----VETISFSFSEFE--PGN--DNLTLQGASLITQSG-VLQLTKINQNGMPAWDSTGRT 51 1lu1.pdb 1 ----ANIQSFSFKNFN----S--PSFILQGDATVS-SG-KLQLTKVKENGIPTPSSLGRA 48 1sbf.pdb 1 ----AETVSFSWNKFV--PKQ--PNMILQGDAIVTSSG-KLQLNKVDENGTPKPSSLGRA 51 1wbla.pdb 1 -----KTISFNFNQFH--QNE--EQLKLQRDARISSNS-VLELTKVVN-GVPTWNSTGRA 49 2ltn.pdb 1 ----TETTSFLITKFS--PDQ--QNLIFQGDGYTT-KE-KLTLT-K-----AVKNTVGRA 44 2pela.pdb 1 ----AETVSFNFNSFS--EGN--PAINFQGDVTVLSNG-NIQLTNL-----NKVNSVGRV 46 5cna.pdb 1 STHETNALHFMFNQFS--KDQ--KDLILQGDATTGTDG-NLELTRVSSNGSPQGSSVGRA 55 F F qgd l Lt Gr 1avba.pdb 47 FYSAPIQINDRTIDNLASFSTNFTFRINAKNI-ENSAYGLAFALVPVGSRPK--L-KGRY 102 1lec.pdb 54 SYSEPVFLWDSTGK-AASFYTSFTFLLKNYG--APTADGLAFFLAPVDSSVK--D-YGGF 107 1len.pdb 45 LYSTPIHIWDRDTGNVANFVTSFTFVIDAPSS-YNVADGFTFFIAPVDTKPQ--T-GGGY 100 1lgc.pdb 45 LYSSPIHIWDSKTGNVANFVTSFTFVIDAPNS-YNVADGFTFFIAPVDTKPQ--T-GGGY 100 1loe.pdb 45 LYSSPIHIWDSKTGNVANFVTSFTFVIDAPNS-YNVADGFTFFIAPVDTKPQ--T-GGGY 100 1lte.pdb 52 LYAKPVHIWDMTTGTVASFETRFSFSIEQPYTRPLPADGLVFFMGPTKSKPA--Q-GYGY 108 1lu1.pdb 49 FYSSPIQIYDKSTGAVASWATSFTVKISAPSK-ASFADGIAFALVPVGSEPR--R-NGGY 104 1sbf.pdb 52 LYSTPIHIWDKETGSVASFAASFNFTFYAPDT-KRLADGLAFFLAPIDTKPQ--T-HAGY 107 1wbla.pdb 50 LYAKPVQVWDSTTGNVASFETRFSFSIRQPFPRPHPADGLVFFIAPPNTQTG--E-GGGY 106 2ltn.pdb 45 LYSSPIHIWDRETGNVANFVTSFTFVINAPNS-YNVADGFTFFIAPVDTKPQ--T-GGGY 100 2pela.pdb 47 LYAMPVRIWSSATGNVASFLTSFSFEMKDIK-DYDPADGIIFFIAPEDTQIPAGSIGGGT 105 5cna.pdb 56 LFYAPVHIWESSAV-VASFEATFTFLIKSPD--SHPADGIAFFISNIDSSIPSGS-TGRL 111 y P A f F f AdG F p 1avba.pdb 103 LGLFNT-T-N-Y-DR-DAHTVAVVFDTV-----------SNRIEIDVNSIRPIATESCN- 145 1lec.pdb 108 LGLFRH-E-TAADPS-KNQVVAVEFDTWINKDWNDP--PYPHIGIDVNSIVSVATTRWEN 162 1len.pdb 101 LGVFNS-K-E-Y-DK-TSQTVAVEFDTFYNAA-WDPSNKERHIGIDVNSIKSVNTKSWN- 153 1lgc.pdb 101 LGVFNS-K-D-Y-DK-TSQTVAVEFDTFYNTA-WDPSNGDRHIGIDVNSIKSINTKSWK- 153 1loe.pdb 101 LGVFNS-K-D-Y-DK-TSQTVAVEFDTFYNTA-WDPSNGDRHIGIDVNSIKSINTKSWA- 153 1lte.pdb 109 LGIFNQ-S-K-Q-DN-SYQTLGVEFDTFSNPW-DPP--QVPHIGIDVNSIRSIKTQPFQ- 159 1lu1.pdb 105 LGVFDS-D-V-Y-NN-SAQTVAVEFDTLSNSG-WDPS--MKHIGIDVNSIKSIATVSWD- 155 1sbf.pdb 108 LGLFNENE-S------GDQVVAVEFDTFRNSW-D-P--PNPHIGINVNSIRSIKTTSWD- 155 1wbla.pdb 107 FGIYNP-L-S------PYPFVAVEFDTFRNTW-D-P--QIPHIGIDVNSVISTKTVPFT- 153 2ltn.pdb 101 LGVFNS-A-E-Y-DK-TTQTVAVEFDTFYNAA-WDPSNRDRHIGIDVNSIKSVNTKSWK- 153 2pela.pdb 106 LGVSDT-KG-------AGHFVGVEFDTYSNSEYNDP--PTDHVGIDVNSVDSVKTVPWN- 154 5cna.pdb 112 LGLFPD-A-------NADTIVAVELDTYPNTDIGDP--SYPHIGIDIKSVRSKKTAKWN- 160 lG v VefDT higIdvnS s T 1avba.pdb 146 --F-GHNNGEKAEVRITYDSPKNDLRVSLLYPSSEEKCHVSATVPLEKEVEDWVSVGFSA 202 1lec.pdb 163 DDAY--GS-SIATAHITYDARSKILTVLLSYE-HGRDYILSHVVDLAKVLPQKVRIGFSA 218 1len.pdb 154 --L---QNGERANVVIAFNAATNVLTVTLTYP-NVTSYTLNEVVPLKDVVPEWVRIGFSA 207 1lgc.pdb 154 --L---QNGKEANVVIAFNGATNVLTVSLTYP-NETSYTLNEVVPLKEFVPEWVRIGFSA 207 1loe.pdb 154 --L---QNGKEANVVIAFNAATNVLTVSLTYP---TSYTLNEVVPLKEFVPEWVRIGFSA 205 1lte.pdb 160 --L---DNGQVANVVIKYDASSKLLHAVLVYPSSGAIYTIAEIVDVKQVLPEWVDVGLSG 214 1lu1.pdb 156 --L---ANGENAEILITYNAATSLLVASLVHPSRRTSYILSERVDITNELPEYVSVGFSA 210 1sbf.pdb 156 --L---ANNKVAKVLITYDASTSLLVASLVYPSQRTSNILSDVVDLKTSLPEWVRIGFSA 210 1wbla.pdb 154 --L---DNGGIANVVIKYDASTKILHVVLVFPSLGTIYTIADIVDLKQVLPESVNVGFSA 208 2ltn.pdb 154 --L---QNGEEANVVIAFNAATNVLTVSLTYP-NVTSYTLSDVVSLKDVVPEWVRIGFSA 207 2pela.pdb 155 --S---VSGAVVKVTVIYDSSTKTLSVAVTND-NGDITTIAQVVDLKAKLPERVKFGFSA 208 5cna.pdb 161 --M---QNGKVGTAHIIYNSVDKRLSAVVSYP-NADSATVSYDVDLDNVLPEWVRVGLSA 214 i L V p V G Sa 1avba.pdb 203 TSGSK----KETTETHNVLSWSFSSNFI---------------------- 226 1lec.pdb 219 GVG-Y------D-EVTYILSWHFFSTLDGTNK------------------ 242 1len.pdb 208 TTG-A------EFAAQEVHSWSFNSQLG---------------------- 228 1lgc.pdb 208 TTG-A------EFAAHEVLSWYFNSELSV---TS---------------- 231 1loe.pdb 206 TTG-A------EFAAHEVLSWYFHSELA---------------------- 226 1lte.pdb 215 ATGAQ----RDAAETHDVYSWSFQASLPE--------------------- 239 1lu1.pdb 211 TTGLS----EGYIETHDVLSWSFASKLPD---DSTAEPLDLASYLVRNVL 253 1sbf.pdb 211 ATGLD----IPGESHDVL-SWSFASNLPH--------------------- 234 1wbla.pdb 209 ATGDPSGKQRNATETHDILSWSFSASLPG--------------------- 237 2ltn.pdb 208 TTG-A------EYAAHEVLSWSFHSELS---------------------- 228 2pela.pdb 209 SGS-L-----GGRQIHLIRSWSFTSTLIT---T----------------- 232 5cna.pdb 215 STG-L------YKETNTILSWSFTSKLKS---N----------------- 237 g SW F l #=========================================ALIGNMENT END============================================= #LEGEND: # # Colours indicate the chemical nature of the amino acid; # Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W} # Blue = Acidic,{D,E} # Magenta = Basic,{K,R} and # Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}. # # The "markup row" below each stretch of the multiple alignment is used to mark completely conserved # residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment. # ################################################EOF#################################################