################################################################################################ # Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm # Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey # Rundate: Sat Jul 23 10:57:36 2005 # Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/lyase_1.html ################################################################################################ #==================================== # Aligned_structures: 5 # 1: 1aosa.pdb # 2: 1dcna.pdb # 3: 1fura.pdb # 4: 1jswa.pdb # 5: 1yfm.pdb # # Length: 531 # Identity: 23/531 ( 4.3%) (Calculated as the percentage of conserved columns in the alignment.) # Similarity: 55/531 ( 10.4%) (Calculated as the percentage of semi-conserved columns in the alignment) # Gaps: 179/531 ( 33.7%) (Calculated as the percentage of columns with atleast one gap.) #===========================================ALIGNMENT START========================================= 1aosa.pdb 1 ---------------------------------IMEKFNAS--IA----YDRHLWEVDVQ 21 1dcna.pdb 1 --------------------------------------------------DQRLSEVDIQ 10 1fura.pdb 1 ----VRSEKDSMGAIDVPADKLWGAQTQRSLEH---FRIST--EKM----PTSLIHALAL 47 1jswa.pdb 1 MSNNIRIEEDLLGTREVPADAYYGVHTLRAIEN---FYISN--NKISDI--PEFVRGMVM 53 1yfm.pdb 1 ---SFRTETDAFGEIHVPADKYWGAQTQRSFQN---FKIGGARERM----PLPLVHAFGV 50 l 1aosa.pdb 22 GSKAYSRGLEKAGLLTKAEMDQILHGLDKV-----------K-LNSN-DE----DIHTAN 64 1dcna.pdb 11 GSMAYAKALEKAGILTKTELAKILSGLEKISEEWS-KG-V-FVVKGS-DE----DIHTAN 62 1fura.pdb 48 TKRAAAKVNEDLGLLSEEKASAIRQAADEVL-A-GQHDDEFP-LAIWQ-TGSGTQSNMNM 103 1jswa.pdb 54 VKKAAAMANKELQTIPKSVANAIIAACDEVL-NNGKCMDQFP-VDVYQ-GGAGTSVNMNT 110 1yfm.pdb 51 LKKSAAIVNESLGGLDPKISKAIQQAADEVA-S-GKLDDHFP-LVVFQ-TGSGTQSNMNA 106 a a e g l I d v 1aosa.pdb 65 ERRLKELIG-------------ATAGKLHTGRS--------RNDQVVTDLRLWMRQTCST 103 1dcna.pdb 63 ERRLKELIG-------------DIAGKLNTGRS--------RNDQVVTDLKLFMKNSLSI 101 1fura.pdb 104 NEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAA-------LLALRKQ 156 1jswa.pdb 111 NEVLANIGLELMGHQKGEYQYLNPNDHVNKCQS--------TNDAYPTGFRIAVYSSLIK 162 1yfm.pdb 107 NEVISNRAIEI----------VHPNNHCNQSQSSNDTFPTVMHIAA-------SLQIQNE 149 l n S 1aosa.pdb 104 LSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVR 163 1dcna.pdb 102 ISTHLLQLIKTLVERAAIEIDVILPGYTNLQKAQPIRWSQFLLSHAVALTRDSERLGEVK 161 1fura.pdb 157 LIPQLKTLTQTLNEKSRAFADIVKIGRTNLQDATPLTLGQEISGWVAMLEHNLKHIEYSL 216 1jswa.pdb 163 LVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNIQRTA 222 1yfm.pdb 150 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 209 l l L d G T LQ A P q l 1aosa.pdb 164 KRINVLPLGSGAIA-GNP--------LGVDRELLRAELNF-GAITLNSMDATSERDFVAE 213 1dcna.pdb 162 KRINVLPLGSGALA-GNP--------LDIDREMLRSELEF-ASISLNSMDAISERDFVVE 211 1fura.pdb 217 PHVAELALGGTAVGTGLNTHPEYARR---VADELAVITCAPFVTAPNKFEALATCDALVQ 273 1jswa.pdb 223 ELLLEVNLGATAIGTGLNTPKEYSPL---AVKKLAEVTGFPCVPAEDLIEATSDCGAYVM 279 1yfm.pdb 210 KTLSFLAQGGTAVGTGLNTKPGFDVK---IAEQISKETGLKFQTAPNRFEALAAHDAIVE 266 l lG A G l n A d v 1aosa.pdb 214 FLFWRSLCMTHLSRMAEDLILYCTK---EFSFVQLSDAYSTGSSLMPQKKNPDSLELIRS 270 1dcna.pdb 212 FLSFATLLMIHLSKMAEDLIIYSTS---EFGFLTLSDAFST---------NPDSLELIRS 259 1fura.pdb 274 AHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPEN-EPGSSIMPGKVNPTQCEALTM 332 1jswa.pdb 280 VHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPEL-QAGSSIMPAKVNPVVPEVVNQ 338 1yfm.pdb 267 CSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPEN-EPGSSIMPGKVNPTQNEALTQ 325 l l k a D l NP E 1aosa.pdb 271 KAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATG-VISTLQIHQ 329 1dcna.pdb 260 KSGRVFGRLASILMVLKGLPSTYNKDLQEDKEAVFDVVDTLTAVLQVATG-VISTLQISK 318 1fura.pdb 333 LCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNR 392 1jswa.pdb 339 VCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCINGITANK 398 1yfm.pdb 326 VCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANE 385 V G m N 1aosa.pdb 330 ENMGQALS--PDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQT 387 1dcna.pdb 319 ENMEKALT--PEMLATDLALYLVRKGVPFRQAHTASGKAVHLAETKGITINNLSLEDLKS 376 1fura.pdb 393 ERINQLLNES-LMLVTALNTHI---------GYDKAAEIAKKAHKEGLTLKAAA--LALG 440 1jswa.pdb 399 EVCEGYVYNS-IGIVTYLNPFI---------GHHNGDIVGKICAETGKSVREVV--LERG 446 1yfm.pdb 386 PRIHELLTKS-LMLVTALNPKI---------GYDAASKVAKNAHKKGITLKESA--LELG 433 e l ml T L a G 1aosa.pdb 388 ---ISPLFSGDVICVWDYRHSVEQYGALGGTARSSVDWQIRQVRALLQAQ- 434 1dcna.pdb 377 ---ISPQFSSDVSQVFNFVNSVEQYTALGGTAKSSVTTQIEQLRELMKKQK 424 1fura.pdb 441 YLS-----EAEFDSWVRPEQM------------------------------ 456 1jswa.pdb 447 LLT-----EAELDDIFSV--------------------------------- 459 1yfm.pdb 434 VLT-----EKEFDEWVVPEHML----------------------------- 450 #=========================================ALIGNMENT END============================================= #LEGEND: # # Colours indicate the chemical nature of the amino acid; # Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W} # Blue = Acidic,{D,E} # Magenta = Basic,{K,R} and # Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}. # # The "markup row" below each stretch of the multiple alignment is used to mark completely conserved # residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment. # ################################################EOF#################################################