################################################################################################ # Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm # Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey # Rundate: Sat Jul 23 08:30:19 2005 # Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/pdc.html ################################################################################################ #==================================== # Aligned_structures: 4 # 1: 1bfd.pdb # 2: 1poxa.pdb # 3: 1pvda.pdb # 4: 1zpda.pdb # # Length: 647 # Identity: 20/647 ( 3.1%) (Calculated as the percentage of conserved columns in the alignment.) # Similarity: 96/647 ( 14.8%) (Calculated as the percentage of semi-conserved columns in the alignment) # Gaps: 187/647 ( 28.9%) (Calculated as the percentage of columns with atleast one gap.) #===========================================ALIGNMENT START========================================= 1bfd.pdb 1 --ASVHGTTYELLRRQGIDTVFGNPGSNELPFLKD--FP-EDFRYILALQEACVVGIADG 55 1poxa.pdb 1 TNILAGAAVIKVLEAWGVDHLYGIPGGSINSIMDALSAERDRIHYIQVRHEEVGAMAAAA 60 1pvda.pdb 1 SEITLGKYLFERLKQVNVNTVFGLPGDFNLSLLDKIYEV-EGMRWAGNANELNAAYAADG 59 1zpda.pdb 1 -SYTVGTYLAERLVQIGLKHHFAVAGDYNLVLLDNLLLN-KNMEQVYCCNELNCGFSAEG 58 g e L g fg pG l ld E A g 1bfd.pdb 56 YAQASRKPAFINLHSAAGTGNAMGALSNAWNSHSPLIVTAGQQTRAMIGVEALLT----N 111 1poxa.pdb 61 DAKLTGKIGVCFGSAGPGGTHLMNGLYDAREDHVPVLALIGQFGTTGMNMDTFQE----- 115 1pvda.pdb 60 YARIK-GMSCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVPSIS----------HHTL 108 1zpda.pdb 59 YARAK-GAAAAVVTYSVGALSAFDAIGGAYAENLPVILISGAPNNNDHAAGHV--LHHAL 115 yA G a a h pv G 1bfd.pdb 112 ----V-DAANLPRPLVKWSYEPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWDKDA 166 1poxa.pdb 116 ----M-NENPIYADVADYNVTAVNAATLPHVIDEAIRRAYAH-QGVAVVQIPVDLPWQQI 169 1pvda.pdb 109 GNGDFTVFHRMSANISETTAMITDIATAPAEIDRCIRTTYVT-QRPVYLGLPANLVDLNV 167 1zpda.pdb 116 GKTDYHYQLEMAKNITAAAEAIYTPEEAPAKIDHVIKTALRE-KKPVYLEIACNIASMPC 174 a P id I a q pvyl p 1bfd.pdb 167 DPQ-S--HHLFDRH-VS-SS-VRL----NDQDLDILVKALNSASNPAIVLGPDVDAANAN 216 1poxa.pdb 170 SAE-DWYASANNY--QTPLL-PEP----DVQAVTRLTQTLLAAERPLIYYGIGAR--KAG 219 1pvda.pdb 168 PAK-L--LQ---TP-ID-MSLKPNDAESEKEVIDTILALVKDAKNPVILADACCSRHDVK 219 1zpda.pdb 175 AAPGP--AS-----ALF-ND-EASDEASLNAAVDETLKFIANRDKVAVLVGSKLRAAGAE 225 a d a p i g a 1bfd.pdb 217 ADCVMLAERLKAPVWVAPSAPRCPFPTRHPCFRGLMP---AGIAAISQLLEGHDVVLVIG 273 1poxa.pdb 220 KELEQLSKTLKIPLMSTYPA-KGIVADRYPAYLGSAN-RVA-QKPANEALAQADVVLFVG 276 1pvda.pdb 220 AETKKLIDLTQFPAFVTPMG-KGSISEQHPRYGGVYVGTLS-KPEVKEAVESADLILSVG 277 1zpda.pdb 226 EAAVKFTDALGGAVATMAAA-KSFFPEENALYIGTSWGEVS-YPGVEKTMKEADAVIALA 283 l l p a k p y G aD vl g 1bfd.pdb 274 APVFRYHQYD-----------PG---QYLKPGTRLISVTCDPLEAAR--AP-MGDA-IVA 315 1poxa.pdb 277 NNYP---------FAEVSKAFKN---T-----RYFLQIDIDPAKLGK--RHKTDIA-VLA 316 1pvda.pdb 278 ALLS------DK--------------T-----KNIVEFHSDH-----MKI--RNATFPGV 305 1zpda.pdb 284 PVFN--------DYS--TTGWTDIPDP-----KKLVLAEPRS-----VVV--NGIRFPSV 321 d 1bfd.pdb 316 DIGAMASALANLVEESSR---------QLPTAAP-EPAK--------------------- 344 1poxa.pdb 317 DAQKTLAAILAQVSERES---------------------TPWWQANLANVKNWRAYLASL 355 1pvda.pdb 306 QMKFVLQKLLTNIA------DAAKGYKP-VAVPARTPAN--------------------- 337 1zpda.pdb 322 HLKDYLTRLAQKVSKKTGSLDFFKSLN--AGE---LKKA--------------------- 355 l l v 1bfd.pdb 345 VDQD-AGRLHPETVFDTLNDMAPENAIYLNESTSTTAQMWQRLNMRNPG-SYYFCA-AGG 401 1poxa.pdb 356 EDKQ-EGPLQAYQVLRAVNKIAEPDAIYSIDVGDINLNANRHLKLTP-SNRHITSNLFAT 413 1pvda.pdb 338 AAVPASTPLKQEWMWNQLGNFLQEGDVVIAETGTSAFGINQT-TFPN-NTYGISQVLWGS 395 1zpda.pdb 356 APADPSAPLVNAEIARQVEALLTPNTTVIAETGDSWFNAQRM-KLPN-GARVEYEMQWGH 413 pL e g n g 1bfd.pdb 402 LGFALPAAIGVQLAEP---E-RQVIAVIGDGSANYSISALWTAAQYNIPTIFVIMNNGTY 457 1poxa.pdb 414 MGVGIPGAIAAKLNYP---E-RQVFNLAGDGGASMTMQDLVTQVQYHLPVINVVFTNCQY 469 1pvda.pdb 396 IGFTTGATLGAAFAAEEIDPKKRVILFIGDGSLQLTVQEISTMIRWGLKPYLFVLNNDGY 455 1zpda.pdb 414 IGWSVPAAFGYAVGAP---E-RRNILMVGDGSFQLTAQEVAQMVRLKLPVIIFLINNYGY 469 G paa g p e r vi GDGs t q t lp i nN Y 1bfd.pdb 458 GALRWFAGVLEAEN--VPGLDVPGIDFRALAKGYG---------VQALKADNLEQLKGSL 506 1poxa.pdb 470 GFIKDEQEDTNQND--FIGVEFNDIDFSKIADGVH---------MQAFRVNKIEQLPDVF 518 1pvda.pdb 456 TIEKLIH----G--PKAQYNEIQGWDHLSLLPTFG-A-----KDYETHRVATTGEWDKLT 503 1zpda.pdb 470 TIEVMIH----D----GPYNNIKNWDYAGLMEVFNGNGGYDSGAAKGLKAKTGGELAEAI 521 D l l 1bfd.pdb 507 QE--ALS--AKGPVLIEVSTV-------------------------- 523 1poxa.pdb 519 EQ--AKAIAQHEPVLIDAVITGDRP-------------------L-- 542 1pvda.pdb 504 QDKSFND--NSKIRMIEIMLPVFDAP--------------------- 527 1zpda.pdb 522 KV--ALAN-TDGPTLIECFIGREDCTEELVKWGKRVAAANSRKPVNK 565 a p lIe #=========================================ALIGNMENT END============================================= #LEGEND: # # Colours indicate the chemical nature of the amino acid; # Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W} # Blue = Acidic,{D,E} # Magenta = Basic,{K,R} and # Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}. # # The "markup row" below each stretch of the multiple alignment is used to mark completely conserved # residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment. # ################################################EOF#################################################