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# Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Sat Jul 23 17:36:55 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/reductases.html
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#====================================
# Aligned_structures: 7
# 1: 1a8p.pdb
# 2: 1fdr.pdb
# 3: 1ndh.pdb
# 4: 1qfja.pdb
# 5: 1qfza.pdb
# 6: 1que.pdb
# 7: 2cnd.pdb
#
# Length: 387
# Identity: 5/387 ( 1.3%) (Calculated as the percentage of conserved columns in the alignment.)
# Similarity: 16/387 ( 4.1%) (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps: 197/387 ( 50.9%) (Calculated as the percentage of columns with atleast one gap.)
#===========================================ALIGNMENT START=========================================
1a8p.pdb 1 --------------------------------SNLNVERVLSVHHWN-----DTLFSFKT 23
1fdr.pdb 1 --------------------------------ADWVTGKVTKVQNWT-----DALFSLTV 23
1ndh.pdb 1 -----------------------PAITL-ENPDIKYPLRLIDKEVVN-----HDTRRFRF 31
1qfja.pdb 1 ---------------------------------TTLSCKVTSVEAIT-----DTVYRVRI 22
1qfza.pdb 1 QVTTEA--PAKVVKHSKKQDE--NIVVNKFKPKEPYVGRCLLNTKITGDDAPGETWHMVF 56
1que.pdb 1 ------TQAKAK---------HADVPVNLYRPNAPFIGKVISNEPLVKEGGIGIVQHIKF 45
2cnd.pdb 1 ---------------------------------GRIHCRLVAKKELS-----RDVRLFRF 22
1a8p.pdb 24 TRN-P---SLRFENGQFVMIGLEV---D-GRPLMRAYSIASPNYE----E-H-LEFFSIK 69
1fdr.pdb 24 HAP-----VLPFTAGQFTKLGLEI-------RVQRAYSYVNSPDN----P-D-LEFYLVT 65
1ndh.pdb 32 ALP-SPEHILGLPVGQHIYLSARI---D-GNLVIRPYTPVSSDDD----KGFVDLVIKVY 82
1qfja.pdb 23 VPD-A---AFSFRAGQYLMVVMD------E-RDKRPFSMASTPDE----KGF-IELHIG- 65
1qfza.pdb 57 STE-G---EVPYREGQSIGIVPDGIDKNGKPHKLRLYSIASSAIGDFGDSKT-VSLCVKR 111
1que.pdb 46 DLTGG---NLKYIEGQSIGIIPPGVDKNGKPEKLRLYSIASTRHGDDVDDKT-ISLCVRQ 101
2cnd.pdb 23 SLP-SPDQVLGLPIGKHIFVCATI---E-GKLCMRAYTPTSMVDE----IGH-FDLLVKV 72
Gq R y s
1a8p.pdb 70 VQ-------------NGPLTSRLQHLK-EG-DELMVSRKPTGTLVTSD----------L- 103
1fdr.pdb 66 VP-------------DGKLSPRLAALK-PG-DEVQVVSEAAGFFVLDE----------V- 99
1ndh.pdb 83 FKDTHP-K---F-PAGGKMSQYLESMK-IG-DTIEFRGPNGLL-VYQGKGKFAIRPDKKS 134
1qfja.pdb 66 ------------------YAKAVMDRIL-KDHQIV-VDIPHGEAWLRD----------D- 94
1qfza.pdb 112 LVYTN--DAG--EVVKGVCSNFLCDLK-PG-SEVKITGPVGKEMLMPK------------ 153
1que.pdb 102 LEYKH--P-ESGETVYGVCSTYLTHIE-PG-SEVKITGPVGKEMLLPD------------ 144
2cnd.pdb 73 YFKNEHPK---F-PNGGLMTQYLDSLP-VG-SYIDVKGPLGHV-EYTGRGSFVIN--GKQ 123
l g
1a8p.pdb 104 LP----G-KHLYMLSTGTGLAPFMSLIQDPEVYE--R---F------EKVVLIHGVRQVN 147
1fdr.pdb 100 PH----C-ETLWMLATGTAIGPYLSILRLGKDLD--R---F------KNLVLVHAARYAA 143
1ndh.pdb 135 SPVIKTV-KSVGMIAGGTGITPMLQVIRAI--MK--D----P--DDHTVCHLLFANQTEK 183
1qfja.pdb 95 -E----E-RPMILIAGGTGFSYARSILLTA--LA--R---N----PNRDITIYWGGREEQ 137
1qfza.pdb 154 -----DPNATVIMLGTGTGIAPFRSFLWKM--FF--EK--HEDYQFNGLAWLFLGVPTSS 202
1que.pdb 145 -----DPEANVIMLATGTGIAPMRTYLWRM--FKDAERAANPEYQFKGFSWLVFGVPTTP 197
2cnd.pdb 124 RN----A-RRLAMICGGSGITPMYQIIQAV--LR--D---QP--EDHTEMHLVYANRTED 169
m Gtg p l
1a8p.pdb 148 ELAYQQFITEHLPQSEYFGEAVKEKLIYYPTVTRE-----S---F-HNQGRLTDLMRS-- 196
1fdr.pdb 144 DLSYLPLMQELEKR-------YEGKLRIQTVVSRE-----T-A-AGSLTGRIPALIES-- 187
1ndh.pdb 184 DILLRPELEELRNE-------HSARFKLWYTVDRAP--E-A---WDYSQG--------FV 222
1qfja.pdb 138 HLYDLCELEALSLK-------H-PGLQVVPVVEQPE--A-G---WRGRTGTVLTAVLQ-- 181
1qfza.pdb 203 SLLYKEEFEKMKEK-------APENFRLDFAVSRE-----QVNDKGEK-MYIQTRMAQ-- 247
1que.pdb 198 NILYKEELEEIQQK-------YPDNFRLTYAISRE-----QKNPQGGR-MYIQDRVAE-- 242
2cnd.pdb 170 DILLRDELDRWAAE-------YPDRLKVWYVIDQVKRPEEG---WKYSVG--------FV 211
1a8p.pdb 197 G-KLFEDIGLPPINPQDDRAMICGSPSML---D-ESCEVLDGF-G-------------LK 237
1fdr.pdb 188 G-ELESTIGL-PMNKETSHVMLCGNPQMV---R-DTQQLLKETRQ-------------MT 228
1ndh.pdb 223 NEEMIRDHL--PPPEEEPLVLMCGPPPMIQYA--C-LPNLERV-G-------------HP 263
1qfja.pdb 182 D--------HG-T-LAEHDIYIAGRFEMA---K-IARDLFCSERN-------------AR 214
1qfza.pdb 248 YAEELWELL----KKDNTFVYMCGLKGME---K-GIDDIMVSL-AAKDGIDWIEYKRT-- 296
1que.pdb 243 HADQLWQLI----KNQKTHTYICGLRGME---E-GIDAALSAA-AAKEGVTWSDYQKD-- 291
2cnd.pdb 212 TEAVLREHV--PEGGDDTLALACGPPPMI---QFAISPNLEKM-K-------------YD 252
cG M
1a8p.pdb 238 ---ISPRMGEPGDYLIER----AFVEK 257
1fdr.pdb 229 ---KH-LRRRPGHMTAEH----YW--- 244
1ndh.pdb 264 ---KE------R-CFAF---------- 270
1qfja.pdb 215 ---ED------R-LFGDAFAFI----- 226
1qfza.pdb 297 LKKAE------Q-WNVEV----S---- 308
1que.pdb 292 LKKAG------R-WHVET----Y---- 303
2cnd.pdb 253 M--AN------S-FVVF---------- 260
#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue = Acidic,{D,E}
# Magenta = Basic,{K,R} and
# Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
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