################################################################################################
# Program: MUSTANG-Lite v0.1: A  Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Fri Aug 12 21:24:01 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/MUSTANG_HOMSTRAD/results/rhv.html
################################################################################################
#====================================
# Aligned_structures: 6
#   1: 1bbt.pdb
#   2: 1r1a.pdb
#   3: 1tme.pdb
#   4: 2mev.pdb
#   5: 2plv.pdb
#   6: 4rhv.pdb
#
# Length:       1033
# Identity:       69/1033 (  6.7%)  (Calculated as the percentage of conserved columns in the alignment.)
# Similarity:    131/1033 ( 12.7%)  (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps:          452/1033 ( 43.8%)  (Calculated as the percentage of columns with atleast one gap.)

#===========================================ALIGNMENT START=========================================


1bbt.pdb                1  ---------------------------------------TTSAGESADPVTTTVENYG-G   20
1r1a.pdb                1  NYIDEVLNE---------VLVVP--NIKESHHTTSNSAPLLDAAETGHTSNVQPEDAIET   49
1tme.pdb                1  ---------------------------------------GSDNAEKGKVSNDDASVDFVA   21
2mev.pdb                1  ---------------------------------------GVENAEKGVTENTDATADFVA   21
2plv.pdb                1  ---------GSSSTAATSRDALP--NTEASGPTHSKEIPALTAVETGATNPLVPSDTVQT   49
4rhv.pdb                1  -----------------------TVASISSGPKHTQKVPILTANETGATMPVLPSDSIET   37
                                                                       E g             

1bbt.pdb               21  ETQI--QRRQHTDVSFIMDRFVKVTPQNQ-------------------------INILDL   53
1r1a.pdb               50  RYVITSQTRDEMSIESFLGRSGCVHISRIKVD--YT---D----YNG-QDINFTKWKITL   99
1tme.pdb               22  EPVK--LPENQTRVAFFYDRAVPIGMLRP-GQ--N--IESTFVYQEN-DLRL-NCLLLTP   72
2mev.pdb               22  QPVY--LPENQTKVAFFYDRSSPIGAFAV-K-S-G-SLESGFAPFSN-KACP-NSVILTP   73
2plv.pdb               50  RHVVQHRSRSESSIESFFARGACVTIMTVDNPA-ST---TNKDK-------LFAVWKITY   98
4rhv.pdb               38  RTTYMHFNGSETDVECFLGRAACVHVTEIQNKDATG---IDNHR---EA-KLFNDWKINL   90
                                           f  R                                        

1bbt.pdb               54  MQ---------------------------VPS----------H-TLVGGLLRASTYYFSD   75
1r1a.pdb              100  QE---------------------------MA-------------Q-IRRKFELFTYVRFD  118
1tme.pdb               73  LPSFCPDSTSG-PVKTKAPVQWRWVRSGG----TTNFPLMTKQDYAFLCF-SPFTYYKCD  126
2mev.pdb               74  GPQFD------PAYDQLRPQRLTEIWGNGNEETSEVFPLKTKQDYSFCLF-SPFVYYKCD  126
2plv.pdb               99  KD---------------------------TV-------------Q-LRRKLEFFTYSRFD  117
4rhv.pdb               91  SS---------------------------LV-------------Q-LRKKLELFTYVRFD  109
                                                                                ftY   D

1bbt.pdb               76  LEIAVKH----------------EGDLTWVPNGAPEK----------ALD-NTTNPTAYH  108
1r1a.pdb              119  SEITLVPCIAGRGD---DI-GHIVMQYMYVPPGAPIPS-K---R-NDFSWQSGTNMSIFW  169
1tme.pdb              127  LEVTVSALG----T-----DTV-ASVLRWAPTGAPADVTDQLIGYTPSLG-ETRNPHMWL  175
2mev.pdb              127  LEVTLSPHT----S-----GAH-GLLVRWCPTGTPTKPTTQVLHEVSSLS-EGRTPQVYS  175
2plv.pdb              118  MELTFVVTANFTETNNGHA-LNQVYQIMYVPPGAPVPE-K---W-DDYTWQTSSNPSIFY  171
4rhv.pdb              110  SEYTILATASQPDSAN-YS-SNLVVQAMYVPPGAPNPK-E---W-DDYTWQSASNPSVFF  162
                            E t                          P GaP                   np    

1bbt.pdb              109  --K--APLTRLALPYTAPHRVLATVY-NGECA-----------------TLPT-----SF  141
1r1a.pdb              170  QHG--QPFPRFSIPFLSIASAYYMFY-DGY--DGDN-------T-S---SKYGSVV-T-N  211
1tme.pdb              176  VGAG-NTQISFVVPYNSPLSVLPAAWFNGW--SDFG-------N-TKDFGVAP-----NA  219
2mev.pdb              176  AGPGTSNQISFVVPYNSPLSVLPAVWYNGH--KRFD-------N-TGDLGIAP-----NS  220
2plv.pdb              172  TYG--TAPARISVPYVGISNAYSHFY-DGF--SKVPLKDQSAALGD---SLYGAASL--N  221
4rhv.pdb              163  KV---GDTSRFSVPYVGLASAYNCFY-DGY--SHDD-------A-E---TQYGITV-L-N  203
                                        Py             G                               

1bbt.pdb              142  NYGAIKATRV--------------TELLYRMKRAETYCPRPLLA------------IHPT  175
1r1a.pdb              212  DMGTICSR--IVTEKQKLSV-VITTHIYHKAKHTKAWCPRPPRAVPYTHSHVTN--YMPE  266
1tme.pdb              220  DFGRLWIQ--G----------NTSASVRIRYKKMKVFCPRPTLF----------F-PWPV  256
2mev.pdb              221  DFGTLFFA--GTK-------PDIKFTVYLRYKNMRVFCPRPTVF----------F-PWPT  260
2plv.pdb              222  DFGILAVR--VVNDHNPTKV-TSKIRVYLKPKHIRVWCPRPPRAVAYYGPGV-D-YKDG-  275
4rhv.pdb              204  HMGSMAFR--IVNEHDEHKT-LVKIRVYHRAKHVEAWIPRAPRALPYTSIGRTN-YPKN-  258
                             G                            K     cPRp                   

1bbt.pdb              176  EAR-HKQKIVAP---------LL--------EDRILTTRNGHTTSTTQSSVGVTYGYATA  217
1r1a.pdb              267  TG---DVTTAIVRRNTI-TTA----------D-RIMQITRGDSTISSDDVANAVVGYGVW  311
1tme.pdb              257  -------------------------------D-RVASDKAGNSATNTQSTVGRLCGYGEA  284
2mev.pdb              261  SGDKIDM----------------T---ENLSD-RVSQDTAGNTVTNTQSTVGRLVGYGTV  300
2plv.pdb              276  -T-----LTPLSTKD-L-TTY---EACGY-SD-RVLQLTLGNSTITTQEAANSVVAYGRW  322
4rhv.pdb              259  -T-----EPVIKKRKGDIKSY------GY-SD-RVQQITLGNSTITTQEAANAVVCYAEW  304
                                                          d R      G     tq        Y   

1bbt.pdb              218  EDFVS-G-PNTSGLETRVV-QAERFFKTHLFDWVTSDSFGRCHLLELPTDH------KGV  268
1r1a.pdb              312  PHYLTPQDATAINKPTQPDTSSNRFYTLESKHWNGSS---KGWWWKLPD--ALKD--MGI  364
1tme.pdb              285  HHGEH-P-ASCADTATDKVLAAERYYTIDLASWTTTQEAFSHIRIPLPH--VLAGEDGGV  340
2mev.pdb              301  HDGEH-P-ASCADTASEKILAVERYYTFKVNDWTSTQKPFEYIRIPLPH--VLSGEDGGV  356
2plv.pdb              323  PEYLRDSEANPVDQPTEPDVAACRFYTLDTVSWTKES---RGWWWKLPD--ALRD--MGL  375
4rhv.pdb              305  PEYLPDVDASDVNKTSKPDTSVCRFYTLDSKTWTTGS---KGWCWKLPD--ALKD--MGV  357
                                   a              R yt     W             LP          G 

1bbt.pdb              269  YGSLTDSYAYMRNGWDVEVTAVGNQFNGGCLLVAMVPELCS-------------------  309
1r1a.pdb              365  FGENMYYHFLGRSGYTVHVQCNASKFHQGTLLVAMIPEHQLA-SAK-HGSV-TAGYKL-T  420
1tme.pdb              341  FGATLRRHYLCKTGWRVQVQCNASQFHAGSLLVFMAPEFYTGKGTKTGDME-PT---D-P  395
2mev.pdb              357  FGATLRRHYLVKTGWRVQVQCNASQFHAGSLLVFMAPEYPTL----------------DV  400
2plv.pdb              376  FGQNMYYHYLGRSGYTVHVQCNASKFHQGALGVFAVPEMCLA-GDS-NTTTMHTSYQN-A  432
4rhv.pdb              358  FGQNMFFHSLGRSGYTVHVQCNATKFHSGCLLVVVIPEHQLA-SHE-GGNV-SVKYTF-T  413
                           fG     h l   G  V Vqcna  Fh G LlV   PE                      

1bbt.pdb              310  -----------IQ------------------------KR--------------ELYQLTL  320
1r1a.pdb              421  HPGEAGRDVSQER---DAS-----LRQPSDDSWLNFD--------------GTLLGNLLI  458
1tme.pdb              396  FTMDT--TWRAPQ----------------GAPT----GYRYDSRTGFFAMNHQNQWQWTV  433
2mev.pdb              401  FAMDN--RWSK------------------DNLPNGTRTQT-N-RKGPFAMDHQNFWQWTL  438
2plv.pdb              433  NPGEKGGT-FTGTFTPD-NNQTSPARRFCPVDYLLG--------------NGTLLGNAFV  476
4rhv.pdb              414  HPGERGID-LS-SANE--------VGGPVKDVLYNM--------------NGTLLGNLLI  449
                                                                                       

1bbt.pdb              321  FPHQFINPRTNMTAHITVPFVGVNRYDQYKVHKPWTLVVMVVAPLTVNTEGAPQIKVYAN  380
1r1a.pdb              459  FPHQFINLRSNNSATLIVPYVNAVPMDSMLRHNNWCLVIIPISPLRSETTSSNIVPITVS  518
1tme.pdb              434  YPHQILNLRTNTTVDLEVPYVNIAPTSSWTQHANWTLVVAVFSPLQYASGSSSDVQITAS  493
2mev.pdb              439  YPHQFLNLRTNTTVDLEVPYVNIAPTSSWTQHASWTLVIAVVAPLTYSTGASTSLDITAS  498
2plv.pdb              477  FPHQIINLRTNNCATLVLPYVNSLSIDSMVKHNNWGIAILPLAPLNFASESSPEIPITLT  536
4rhv.pdb              450  FPHQFINLRTNNTATIVIPYINSVPIDSMTRHNNVSLMVIPIAPLTVPTGATPSLPITVT  509
                            PHQ  NlRtN       Pyvn     s   H  w l      PL           it  

1bbt.pdb              381  IAPTNVHVAGEFPSK----E--G-IFPVACSDGYGGLVTTDPKTADPVYGKVFNPPRNQL  433
1r1a.pdb              519  ISPMCAEFSGARAK-NIK-Q----GLPVYITPGSGQFMTTDDMQSPCALPWYHPTKEISI  572
1tme.pdb              494  IQPVNPVFNGLRHE-TVI-A--S-PIAVTVREHKGCFYSTNPDTTVPIYGKTISTPNDYM  548
2mev.pdb              499  IQPVRPVFNGLRHE-VLS--RQS-PIPVTIREHAGTWYSTLPDSTVPIYGKTPVAPANYM  554
2plv.pdb              537  IAPMCCEFNGLRNI-TLPRL---QGLPVMNTPGSNQYLTADNFQSPCALPEFDVTPPIDI  592
4rhv.pdb              510  IAPMCTEFSGIRSK-SIVPQ----GLPTTTLPGSGQFLTTDDRQSPSALPNYEPTPRIHI  564
                           I P    f G r              pv      g    t               p    

1bbt.pdb              434  PGRFTNLLDVAEACPTFLRFE--------------GGVPYVTTKTD-S-DRVLAQFDMSL  477
1r1a.pdb              573  PGEVKNLIEMCQ-VDTLIPVN---NVGNNV-GNVS--MYTVQLGNQTGMAQKVFSIKVDI  625
1tme.pdb              549  CGEFSDLLELCK-LPTFLGNPNSN-N---------KRYPYFSATNS-VPTTSLVDYQVAL  596
2mev.pdb              555  VGEYKDFLEIAQ-IPTFIGNK---VP---------NAVPYIEASNTAVKTQPLAVYQVTL  601
2plv.pdb              593  PGEVKNMMELAE-IDTMIPFD---LSATKK-NTME--MYRVRLSDKPHTDDPILCLSLSP  645
4rhv.pdb              565  PGKVHNLLEIIQ-VDTLIPMN---NTHT--KDEVN--SYLIPLNANRQN-EQVFGTNLFI  615
                            G      e      T                                            

1bbt.pdb              478  AA-KHMSNTFLAGLAQYYTQYSGTINLHFMFTGPTDAKARYMVAYAPPGMEPPKTPEAAA  536
1r1a.pdb              626  TS-TPLATTLIGEIASYYTHWTGSLRFSFMFCGTANTTLKLLLAYTPPGIDEPTTRKDAM  684
1tme.pdb              597  SC-SCMCNSMLAAVARNFNQYRGSLNFLFVFTGAAMVKGKFLIAYTPPGAGKPTTRDQAM  655
2mev.pdb              602  SC-SCLANTFLAALSRNFAQYRGSLVYTFVFTGTAMMKGKFLIAYTPPGAGKPTSRDQAM  660
2plv.pdb              646  ASDPRLSHTMLGEILNYYTHWAGSLKFTFLFCGSMMATGKLLVSYAPPGADPPKKRKEAM  705
4rhv.pdb              616  GD-GVFKTTLLGEIVQYYTHWSGSLRFSLMYTGPALSSAKLILAYTPPGARGPQDRREAM  674
                                   t l           Gsl   f f G      k   aY PPG   P  r  Am

1bbt.pdb              537  HCIHAEWDTGLNSKFTFSIPYLSAADYTYTASDVAETTNVQGWVCLFQITHG---K--A-  590
1r1a.pdb              685  LGTHVVWDVGLQSTISLVVPWVSASHFRLTADNK---YSMAGYITCWYQTN-LVVPPSTP  740
1tme.pdb              656  QATYAIWDLGLNSSFVFTAPFISPTHYRQTSYTSAA--SVDGWVTVWQLTP-LTYPSGTP  712
2mev.pdb              661  QATYAIWDLGLNSSYSFTVPFISPTHFRMVGTDQANITNVDGWVTVWQLTP-LTYPPGCP  719
2plv.pdb              706  LGTHVIWDIGLQSSCTMVVPWISNTTYRQTIDDS---FTEGGYISVFYQTR-IVVPLSTP  761
4rhv.pdb              675  LGTHVVWDIGLQSTIVMTIPWTSGVQFRYTDPDT---YTSAGFLSCWYQTS-LILPPETT  730
                             t   WD GL S      P  S    r t           G       T     p    

1bbt.pdb              591  DGDALVVLASAGKDFELRLPVDARAE----------------------------SGNTGS  622
1r1a.pdb              741  QTADMLCFVSACKDFCLRMARDTDLHIQSG--PIEQ---------Y-----F--------  776
1tme.pdb              713  VNSDILTLVSAGDDFTLRMPISPT--------KWVP----------------Q-SGNEGV  747
2mev.pdb              720  TSAKILTMVSAGKDFSLKMPISPA--------PWSP----------------QSEGNEGV  755
2plv.pdb              762  REMDILGFVSACNDFSVRLLRDTTHIEQKAGAQVSSQKVGAHENSNSTINYT--------  813
4rhv.pdb              731  GQVYLLSFISACPDFKLRLMKDTQTISQTV--ALTE------------------------  764
                                l   SA  DF lr                                          

1bbt.pdb              623  IINNYYMQ-QYQNSMDT--QLG--NDWFSKLASSA-----FSGLFGA-LLA---------  662
1r1a.pdb              777  -NINYFKDAASSGASRL--D----------------------------------------  793
1tme.pdb              748  IINNFYSN-QYQNSIDL--SAS--------------------------------------  766
2mev.pdb              756  IINNFYSN-QYQNSIDL--SAN-------------ATGSDPPKTYGQFSN-LLSGAVNAF  798
2plv.pdb              814  -TINYYRDSASNAASKQDFS--QDPSKFTEP-----------------------IKDVLI  847
4rhv.pdb              765  --INYYKDAASTSSAGQSLS--MDPSKFTEP-----------------------VKDLML  797
                              N y                                                      

1bbt.pdb                   -------------     
1r1a.pdb                   -------------     
1tme.pdb                   -------------     
2mev.pdb              799  SN--MLPLLA---  806
2plv.pdb              848  --KTAP----MLN  854
4rhv.pdb              798  --KGAP----ALN  804
                                        


#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red         = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue        = Acidic,{D,E}
# Magenta     = Basic,{K,R} and
# Green       = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
################################################EOF#################################################