1n97:A (SER170) to (ARG356) CRYSTAL STUCTURE OF CYP175A1 FROM THERMUS THERMOPHILLUS STRAIN HB27 | P450, ELECTRON TRANSPORT
4wmz:A (THR223) to (THR490) S. CEREVISIAE CYP51 COMPLEXED WITH FLUCONAZOLE IN THE ACTIVE SITE | FLUCONAZOLE, CYP51, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX
4wnu:A (ILE233) to (HIS463) HUMAN CYTOCHROME P450 2D6 QUINIDINE COMPLEX | CYP2D6, P450 2D6, CYTOCHROME P450, MONOOXYGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
4wnv:B (ILE233) to (HIS463) HUMAN CYTOCHROME P450 2D6 QUININE COMPLEX | CYP2D6, P450 2D6, P450, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4h24:D (HIS171) to (GLU373) CYTOCHROME P450BM3-CIS CYCLOPROPANATION CATALYST | CYTOCHROME P450, ENZYMATIC CYCLOPROPANATION, DIRECTED EVOLUTION, NON- NATURAL FUNCTION, OXIDOREDUCTASE
4wpd:A (ASP140) to (ARG337) X-RAY CRYSTAL STRUCTURE OF CYP119 COMPLEXED WITH 4-(4-FLOUROPHENYL)- 1H-IMIDAZOLE | CYTOCHROME P450, 4-(4-FLOUROPHENYL)-1H-IMIDAZOLE LIGAND BOUND, OXIDOREDUCTASE
4wqj:A (ASP140) to (ARG337) CRYSTAL STRUCTURE OF CYP119 FROM SULFOLOBUS ACIDOCALDARIUS, COLLECTED AT 298K AND COMPLEXED WITH 4-(4-BROMOPHENYL)-1H IMIDAZOLE | OXIDOREDUCTASE
3ejb:B (PRO150) to (ARG364) CRYSTAL STRUCTURE OF P450BIOI IN COMPLEX WITH TETRADECANOIC ACID LIGATED ACYL CARRIER PROTEIN | PROTEIN-PROTEIN COMPLEX, CYTOCHROME P450 FOLD, CARRIER PROTEIN, 4- HELIX BUNDLE, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS, PHOSPHOPANTETHEINE, BIOTIN BIOSYNTHESIS, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE-LIPID TRANSPORT COMPLEX
3ejb:D (GLU129) to (ARG364) CRYSTAL STRUCTURE OF P450BIOI IN COMPLEX WITH TETRADECANOIC ACID LIGATED ACYL CARRIER PROTEIN | PROTEIN-PROTEIN COMPLEX, CYTOCHROME P450 FOLD, CARRIER PROTEIN, 4- HELIX BUNDLE, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS, PHOSPHOPANTETHEINE, BIOTIN BIOSYNTHESIS, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE-LIPID TRANSPORT COMPLEX
3ejb:F (ARG154) to (ARG364) CRYSTAL STRUCTURE OF P450BIOI IN COMPLEX WITH TETRADECANOIC ACID LIGATED ACYL CARRIER PROTEIN | PROTEIN-PROTEIN COMPLEX, CYTOCHROME P450 FOLD, CARRIER PROTEIN, 4- HELIX BUNDLE, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS, PHOSPHOPANTETHEINE, BIOTIN BIOSYNTHESIS, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE-LIPID TRANSPORT COMPLEX
3eje:B (ARG154) to (ARG364) CRYSTAL STRUCTURE OF P450BIOI IN COMPLEX WITH OCTADEC-9Z- ENOIC ACID LIGATED ACYL CARRIER PROTEIN | PROTEIN-PROTEIN COMPLEX, CYTOCHROME P450 FOLD, CARRIER PROTEIN, 4-HELIX BUNDLE, CYTOPLASM, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS, PHOSPHOPANTETHEINE, BIOTIN BIOSYNTHESIS, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE/LIPID TRANSPORT COMPLEX
3eje:D (ARG154) to (GLN363) CRYSTAL STRUCTURE OF P450BIOI IN COMPLEX WITH OCTADEC-9Z- ENOIC ACID LIGATED ACYL CARRIER PROTEIN | PROTEIN-PROTEIN COMPLEX, CYTOCHROME P450 FOLD, CARRIER PROTEIN, 4-HELIX BUNDLE, CYTOPLASM, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS, PHOSPHOPANTETHEINE, BIOTIN BIOSYNTHESIS, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE/LIPID TRANSPORT COMPLEX
3eje:F (ARG154) to (ARG364) CRYSTAL STRUCTURE OF P450BIOI IN COMPLEX WITH OCTADEC-9Z- ENOIC ACID LIGATED ACYL CARRIER PROTEIN | PROTEIN-PROTEIN COMPLEX, CYTOCHROME P450 FOLD, CARRIER PROTEIN, 4-HELIX BUNDLE, CYTOPLASM, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS, PHOSPHOPANTETHEINE, BIOTIN BIOSYNTHESIS, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE/LIPID TRANSPORT COMPLEX
3eje:H (ARG154) to (ARG364) CRYSTAL STRUCTURE OF P450BIOI IN COMPLEX WITH OCTADEC-9Z- ENOIC ACID LIGATED ACYL CARRIER PROTEIN | PROTEIN-PROTEIN COMPLEX, CYTOCHROME P450 FOLD, CARRIER PROTEIN, 4-HELIX BUNDLE, CYTOPLASM, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS, PHOSPHOPANTETHEINE, BIOTIN BIOSYNTHESIS, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE/LIPID TRANSPORT COMPLEX
3ekd:A (HIS171) to (PRO382) CRYSTAL STRUCTURE OF THE A264M HEME DOMAIN OF CYTOCHROME P450 BM3 | HEME LIGATION, CYTOCHROME P450, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL- BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
4h6o:A (ARG195) to (ILE413) STEROL 14-ALPHA DEMETHYLASE (CYP51)FROM TRYPANOSOMA CRUZI IN COMPLEX WITH THE INHIBITOR NEU321 (1-(3-(4-CHLORO-3,5-DIMETHYLPHENOXY) BENZYL)-1H-IMIDAZOLE | STEROL 14-ALPHA DEMETHYLASE (CYP51), CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
1odo:A (PRO160) to (PHE375) 1.85 A STRUCTURE OF CYP154A1 FROM STREPTOMYCES COELICOLOR A3(2) | P450 MONOOXYGENASE, STREPTOMYCES, CYTOCHROME, OXIDOREDUCTASE
2q9g:A (LYS209) to (ARG457) CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 46A1 | CYP46A1, P450 46A1, P450, MONOOXYGENASE, CHOLESTEROL METABOLIC ENZYME, OXIDOREDUCTASE, HEME
4ips:A (PRO153) to (PHE319) SUBSTRATE AND REACTION SPECIFICITY OF MYCOBACTERIUM TUBERCULOSIS CYTOCHROME P450 CYP121 | PROTEIN-LIGAND COMPLEX, P450 FOLD, OXYDASE, CYCLO-DIPEPTIDE, OXIDOREDUCTASE
3t3s:A (SER224) to (ASN459) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH PILOCARPINE | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
1ea1:A (GLY163) to (ASN380) CYTOCHROME P450 14 ALPHA-STEROL DEMETHYLASE (CYP51) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH FLUCONAZOLE | OXIDOREDUCTASE, CYTOCHROME P450, 14 ALPHA-STEROL DEMETHYLASE, AZOLE INHIBITORS
2rfb:A (MET127) to (PHE325) CRYSTAL STRUCTURE OF A CYTOCHROME P450 FROM THE THERMOACIDOPHILIC ARCHAEON PICROPHILUS TORRIDUS | CYTOCHROME P450 THERMOPHILE, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE
1f24:A (LEU164) to (GLU326) CRYSTAL STRUCTURE OF NO COMPLEX OF THR243ALA MUTANTS OF CYTOCHROME P450NOR | NITRIC OXIDE REDUCTASE, CYTOCHROME P450NOR, OXIDOREDUCTASE
2uuq:A (PRO159) to (GLU334) CRYSTAL STRUCTURE OF CYP130 FROM MYCOBACTERIUM TUBERCULOSIS IN THE LIGAND-FREE FORM | P450, IRON, HEME, MONOOXYGENASE, METAL-BINDING, OXIDOREDUCTASE, HYPOTHETICAL PROTEIN
1f4t:B (ASP140) to (HIS293) THERMOPHILIC P450: CYP119 FROM SULFOLOBUS SOLFACTARICUS WITH 4- PHENYLIMIDAZOLE BOUND | P450 FOLD, OXIDOREDUCTASE
1f4u:A (LYS141) to (ARG337) THERMOPHILIC P450: CYP119 FROM SULFOLOBUS SOLFACTARICUS | P450 FOLD, OXIDOREDUCTASE
1f4u:B (LYS141) to (ARG337) THERMOPHILIC P450: CYP119 FROM SULFOLOBUS SOLFACTARICUS | P450 FOLD, OXIDOREDUCTASE
2uvn:A (TRP163) to (GLU334) CRYSTAL STRUCTURE OF ECONAZOLE-BOUND CYP130 FROM MYCOBACTERIUM TUBERCULOSIS | IRON, HEME, MONOOXYGENASE, METAL-BINDING, OXIDOREDUCTASE
2v0m:D (ILE230) to (TRP408) CRYSTAL STRUCTURE OF HUMAN P450 3A4 IN COMPLEX WITH KETOCONAZOLE | METAL-BINDING, TRANSMEMBRANE, OXIDOREDUCTASE, ENDOPLASMIC RETICULUM, DRUG METABOLIZING ENZYME, KETOCONAZOL, POLYMORPHISM, MONOOXYGENASE, P450, NADP, IRON, HEME, CYP3A4, MEMBRANE, MICROSOME
1rom:A (LEU164) to (GLU326) CRYSTAL STRUCTURE OF NITRIC REDUCTASE FROM DENITRIFYING FUNGUS FUSARIUM OXYSPORUM | NITRIC OXIDE REDUCTASE, CYTOCHROME P450NOR, OXIDOREDUCTASE
2ve4:A (PHE171) to (GLN411) SUBSTRATE FREE CYANOBACTERIAL CYP120A1 | OXIDOREDUCTASE, MONOOXYGENASE, METAL-BINDING, HEME, IRON
2ve4:B (PHE171) to (GLN411) SUBSTRATE FREE CYANOBACTERIAL CYP120A1 | OXIDOREDUCTASE, MONOOXYGENASE, METAL-BINDING, HEME, IRON
2ve3:A (PHE171) to (ASN376) RETINOIC ACID BOUND CYANOBACTERIAL CYP120A1 | OXIDOREDUCTASE, MONOOXYGENASE, METAL-BINDING, HEME, IRON
2ve3:B (GLN169) to (ASN376) RETINOIC ACID BOUND CYANOBACTERIAL CYP120A1 | OXIDOREDUCTASE, MONOOXYGENASE, METAL-BINDING, HEME, IRON
4z5p:B (ARG160) to (ARG368) CRYSTAL STRUCTURE OF THE LNMA CYTOCHROME P450 HYDROXYLASE FROM THE LEINAMYCIN BIOSYNTHETIC PATHWAY OF STREPTOMYCES ATROOLIVACEUS S-140 AT 1.9 A RESOLUTION | HYDROXYLASE, LEINAMYCIN, HEME, MONOOXYGENASE, OXIDOREDUCTASE, STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, ENZYME DISCOVERY FOR NATURAL PRODUCT BIOSYNTHESIS, NATPRO
2vku:A (GLY163) to (ASN380) 4,4'-DIHYDROXYBENZOPHENONE MIMICS STEROL SUBSTRATE IN THE BINDING SITE OF STEROL 14ALPHA-DEMETHYLASE (CYP51) IN THE X-RAY STRUCTURE OF THE COMPLEX | STEROID BIOSYNTHESIS, CYP51-4, CYTOPLASM, ALPHA-BETA, HEME CO-FACTOR, LIPID SYNTHESIS, STEROL BIOSYNTHESIS, 4'- DIHYDROXYBENZOPHENONE COMPLEX, NADP, IRON, HEME, MONOOXYGENASE, METAL-BINDING, OXIDOREDUCTASE
1gei:A (LEU164) to (PHE325) STRUCTURAL CHARACTERIZATION OF N-BUTYL-ISOCYANIDE COMPLEXES OF CYTOCHROMES P450NOR AND P450CAM | CYTOCROME P450NOR (FE-II), ISOCYANIDE COMPLEXE FORM, X-RAY CRYSTALLOGRAPHY, OXIDOREDUCTASE
1gem:A (PRO170) to (ARG377) STRUCTURAL CHARACTERIZATION OF N-BUTYL-ISOCYANIDE COMPLEXES OF CYTOCHROMES P450NOR AND P450CAM | CYTOCROME P450CAM (FE-III), ISOCYANIDE COMPLEXE FORM, X-RAY CRYSTALLOGRAPHY, OXIDOREDUCTASE
4zdy:A (THR237) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) Y140F MUTANT COMPLEXED WITH ITRACONAZOLE | ITRACONAZOLE, CYP51, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX, RESISTANCE MUTATION, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4zdz:A (THR237) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) Y140F MUTANT COMPLEXED WITH FLUCONAZOLE | CYP51, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, RESISTANCE MUTATION
4ze0:A (THR223) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) Y140F MUTANT COMPLEXED WITH VORICONAZOLE | CYP51, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX, Y140F, RESISTANCE MUTATION
4ze1:A (ALA226) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 Y140F MUTANT COMPLEXED WITH POSACONAZOLE IN THE ACTIVE SITE | CYP51, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, RESISTANCE MUTATION
4ze3:A (THR237) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) Y140H MUTANT COMPLEXED WITH FLUCONAZOLE | FLUCONAZOLE, CYP51, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, Y140H, RESISTANCE MUTATION, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX
1se6:A (ARG168) to (ARG373) CRYSTAL STRUCTURE OF STREPTOMYCES COELICOLOR A3(2) CYP158A2 FROM ANTIBIOTIC BIOSYNTHETIC PATHWAYS | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP158A2, ANTIBIOTIC BIOSYNTHESIS, OXIDOREDUCTASE
4zgx:D (PRO241) to (HIS470) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
4zgx:E (PRO241) to (HIS470) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
4zgx:I (PRO241) to (HIS470) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
4zgx:K (PRO241) to (HIS470) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
2w0b:A (GLY163) to (ASN380) CYP51 OF M. TUBERCULOSIS BOUND TO AN INHIBITOR 3-{[(4- METHYLPHENYL)SULFONYL]AMINO}PROPYL PYRIDIN-4-YLCARBAMATE | STEROID BIOSYNTHESIS, PROTEIN-INHIBITOR COMPLEX, METAL-BINDING, OXIDOREDUCTASE, LIPID SYNTHESIS, NADP, IRON, HEME, CYTOPLASM, MONOOXYGENASE, X-RAY DIFFRACTION, STEROL BIOSYNTHESIS
1h5z:A (GLY163) to (ASN380) CYTOCHROME P450 14 ALPHA-STEROL DEMETHYLASE (CYP51) FROM MYCOBACTERIUM TUBERCULOSIS IN FERRIC LOW-SPIN STATE | OXIDOREDUCTASE, CYTOCHROME P450, 14 ALPHA-STEROL DEMETHYLASE, FERRIC LOW-SPIN, STEROL BIOSYNTHESIS, MONOOXYGENASE, ELECTRON TRANSPORT
4lht:A (PRO160) to (ARG367) CRYSTAL STRUCTURE OF P450CIN Y81F MUTANT, CRYSTALLIZED IN 3 MM 1,8- CINEOLE | P450 MONOOXYGENASE, CINDOXIN, OXIDOREDUCTASE
2h7r:A (ILE174) to (ARG377) L244A MUTANT OF CYTOCHROME P450CAM COMPLEXED WITH IMIDAZOLE | AZOLE DRUGS, IMIDAZOLE BINDING, CYTOCHROME P450 INHIBITION, PROTEIN MALEABILITY, ACTIVE SITE CONFORMATION, OXIDOREDUCTASE
3iw0:A (GLU173) to (HIS397) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS CYTOCHROME P450 CYP125, C2221 CRYSTAL FORM | CHOLESTEROL, CYTOCHROME P450, MONOOXYGENASE, TUBERCULOSIS, HEME, IRON, METAL-BINDING, OXIDOREDUCTASE
2wgy:A (THR164) to (GLU334) CRYSTAL STRUCTURE OF THE G243A MUTANT OF CYP130 FROM M. TUBERCULOSIS | COMPLETE PROTEOME, HEME, HYPOTHETICAL PROTEIN, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE
2wiv:A (ALA311) to (PHE476) CYTOCHROME-P450 XPLA HEME DOMAIN P21 | CYT-P450, HEME, RDX, BIOREMEDIATION, ELECTRON TRANSPORT
2wm5:A (PRO183) to (PHE353) X-RAY STRUCTURE OF THE SUBSTRATE-FREE MYCOBACTERIUM TUBERCULOSIS CYTOCHROME P450 CYP124 | METAL-BINDING, OXIDOREDUCTASE, OMEGA-HYDROXYLATION, P450, IRON, HEME, FATTY ACID, MONOOXYGENASE
4lxj:A (THR237) to (THR490) SACCHAROMYCES CEREVISIAE LANOSTEROL 14-ALPHA DEMETHYLASE WITH LANOSTEROL BOUND | CYTOCHROME P450, OXIDOREDUCTASE
1ue8:A (ASP136) to (LYS337) CRYSTAL STRUCTURE OF THERMOPHILIC CYTOCHROME P450 FROM SULFOLOBUS TOKODAII | ALPHA-DOMAIN, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
1io7:A (PRO137) to (ARG337) THERMOPHILIC CYTOCHROME P450 (CYP119) FROM SULFOLOBUS SOLFATARICUS: HIGH RESOLUTION STRUCTURAL ORIGIN OF ITS THERMOSTABILITY AND FUNCTIONAL PROPERTIES | THERMOPHILIC, CYTOCHROMO P450, CRYSTAL STRUCTURE, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, OXIDOREDUCTASE
1io8:A (LYS141) to (HIS293) THERMOPHILIC CYTOCHROME P450 (CYP119) FROM SULFOLOBUS SOLFATARICUS: HIGH RESOLUTION STRUCTURAL ORIGIN OF ITS THERMOSTABILITY AND FUNCTIONAL PROPERTIES | THERMOPHILIC, CYTOCHROMO P450, CRYSTAL STRUCTURE, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, OXIDOREDUCTASE, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES
1io8:B (ASP640) to (HIS793) THERMOPHILIC CYTOCHROME P450 (CYP119) FROM SULFOLOBUS SOLFATARICUS: HIGH RESOLUTION STRUCTURAL ORIGIN OF ITS THERMOSTABILITY AND FUNCTIONAL PROPERTIES | THERMOPHILIC, CYTOCHROMO P450, CRYSTAL STRUCTURE, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, OXIDOREDUCTASE, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES
1iwk:A (PRO170) to (ARG377) PUTIDAREDOXIN-BINDING STABLILIZES AN ACTIVE CONFORMER OF CYTOCHROME P450CAM IN ITS REDUCED STATE; CRYSTAL STRUCTURE OF MUTANT(112K) CYTOCHROME P450CAM | PUTIDAREDOXIN BINDING SITE, CYTOCHROME P450CAM, CRYSTAL STRUCTURE, MUTANT 112K, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, OXIDOREDUCTASE
1izo:B (GLU158) to (VAL381) CYTOCHROME P450 BS BETA COMPLEXED WITH FATTY ACID | HEME PROTEIN, PROTEIN-FATTY ACID COMPLEX, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, OXIDOREDUCTASE
1izo:C (LYS160) to (VAL381) CYTOCHROME P450 BS BETA COMPLEXED WITH FATTY ACID | HEME PROTEIN, PROTEIN-FATTY ACID COMPLEX, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, OXIDOREDUCTASE
2x5l:A (GLU173) to (HIS397) X-RAY STRUCTURE OF THE SUBSTRATE-FREE MYCOBACTERIUM TUBERCULOSIS CYTOCHROME P450 CYP125, ALTERNATIVE CRYSTAL FORM | OXIDOREDUCTASE, CHOLESTEROL DEGRADATION, MONOOXYGENASE, METAL-BINDING
5ajr:A (ALA194) to (PRO395) STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA CRUZI IN COMPLEX WITH THE 1-TETRAZOLE DERIVATIVE VT-1161 ((R)-2-( 2,4-DIFLUOROPHENYL)-1,1-DIFLUORO-3-(1H-TETRAZOL-1-YL)-1-(5- (4-(2,2,2-TRIFLUOROETHOXY)PHENYL)PYRIDIN-2-YL)PROPAN-2-OL) | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE
3wrl:E (PRO175) to (ASN332) CRYSTAL STRUCTURE OF P450CAM | OXIDOREDUCTASE, METAL-BINDING
3zg2:A (ALA194) to (ILE413) STEROL 14 ALPHA-DEMETHYLASE (CYP51) FROM TRYPANOSOMA CRUZI IN COMPLEX WITH THE PYRIDINE INHIBITOR (S)-2-(4-CHLOROPHENYL)-2- (PYRIDIN-3-YL)-1-(4-(4-(TRIFLUOROMETHYL)PHENYL)PIPERAZIN-1-YL) ETHANONE (EPL-BS1246,UDO) | OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE, INHIBITOR
4ny4:A (ILE230) to (ILE427) CRYSTAL STRUCTURE OF CYP3A4 IN COMPLEX WITH AN INHIBITOR | CYTOCHROME P-450, CYP3A4, INHIBITOR, STRUCTURE-BASED DRUG DESIGN, DRUG METABOLISM, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3juv:A (GLU221) to (TRP415) CRYSTAL STRUCTURE OF HUMAN LANOSTEROL 14ALPHA-DEMETHYLASE (CYP51) | CYTOCHROME P450, STEROL 14ALPHA-DEMETHYLASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, ALTERNATIVE SPLICING, CHOLESTEROL BIOSYNTHESIS, ENDOPLASMIC RETICULUM, HEME, IRON, LIPID SYNTHESIS, MEMBRANE, METAL-BINDING, MICROSOME, MONOOXYGENASE, NADP, OXIDOREDUCTASE, POLYMORPHISM, STEROID BIOSYNTHESIS, STEROL BIOSYNTHESIS, TRANSMEMBRANE
2nz5:A (ASP170) to (PRO332) STRUCTURE AND FUNCTION STUDIES OF CYTOCHROME P450 158A1 FROM STREPTOMYCES COELICOLOR A3(2) | STREPTOMYCES; CYTOCHROME P450 OXIDOREDUCTASE; CYP158A1; FLAVIOLIN; C- C COUPLING ACTIVITY, OXIDOREDUCTASE
3k9v:B (LYS266) to (GLY456) CRYSTAL STRUCTURE OF RAT MITOCHONDRIAL P450 24A1 S57D IN COMPLEX WITH CHAPS | MITOCHONDRIAL CYTOCHROME P450, MONOTOPIC MEMBRANE PROTEIN, MONOOXYGENASE, VITAMIN D HORMONE METABOLISM, ADRENODOXIN, OXIDOREDUCTASE
3k9y:A (VAL257) to (LYS482) CRYSTAL STRUCTURE OF RAT MITOCHONDRIAL P450 24A1 S57D IN COMPLEX WITH CYMAL-5 | MITOCHONDRIAL CYTOCHROME P450, MONOTOPIC MEMBRANE PROTEIN, MONOOXYGENASE, VITAMIN D HORMONE METABOLISM, ADRENODOXIN, OXIDOREDUCTASE
3khm:A (ASN193) to (PRO395) CRYSTAL STRUCTURE OF STEROL 14ALPHA-DEMETHYLASE (CYP51) FROM TRYPANOSOMA CRUZI IN COMPLEX WITH INHIBITOR FLUCONAZOLE | STEROL 14-ALPHA DEMETHYLASE, CYP51, CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, ENDOPLASMIC RETICULUM, TRANSMEMBRANE PROTEIN, STEROL BIOSYNTHESIS, LIPIDS, MEMBRANE, IRON, HEME THIOLATE PROTEIN
2zqx:B (PHE135) to (VAL381) CYTOCHROME P450BSBETA COCRYSTALLIZED WITH HEPTANOIC ACID | PEROXIGENESE, OXIDOREDUCTASE, HEME PROTEIN, HEPTANOIC ACID, HEME, IRON, METAL-BINDING, MONOOXYGENASE
3koh:A (LYS195) to (PHE458) CYTOCHROME P450 2E1 WITH OMEGA-IMIDAZOLYL OCTANOIC ACID | CYP2E1, P450 2E1, MONOOXYGENASE, HEME, FATTY ACID, MICROSOME, MEMBRANE, OXIDOREDUCTASE, ENDOPLASMIC RETICULUM, IRON, METAL-BINDING
3koh:B (ASP193) to (GLN456) CYTOCHROME P450 2E1 WITH OMEGA-IMIDAZOLYL OCTANOIC ACID | CYP2E1, P450 2E1, MONOOXYGENASE, HEME, FATTY ACID, MICROSOME, MEMBRANE, OXIDOREDUCTASE, ENDOPLASMIC RETICULUM, IRON, METAL-BINDING
3ksw:A (ALA194) to (TYR443) CRYSTAL STRUCTURE OF STEROL 14ALPHA-DEMETHYLASE (CYP51) FROM TRYPANOSOMA CRUZI IN COMPLEX WITH AN INHIBITOR VNF ((4-(4- CHLOROPHENYL)-N-[2-(1H-IMIDAZOL-1-YL)-1-PHENYLETHYL]BENZAMIDE) | STEROL 14-ALPHA DEMETHYLASE, CYP51, CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, ENDOPLASMIC RETICULUM, TRANSMEMBRANE PROTEIN, STEROL BIOSYNTHESIS, LIPIDS, MEMBRANE, IRON, HEME THIOLATE PROTEIN, LIPID SYNTHESIS, METAL-BINDING, NADP, STEROID BIOSYNTHESIS
5de9:A (ARG168) to (ARG373) THE ROLE OF ILE87 OF CYP158A2 IN OXIDATIVE COUPLING REACTION | CYP158A2, CYTOCHROME P450, OXIDATIVE COUPLING REACTION, OXIDOREDUCTASE
5de9:B (ARG168) to (ARG373) THE ROLE OF ILE87 OF CYP158A2 IN OXIDATIVE COUPLING REACTION | CYP158A2, CYTOCHROME P450, OXIDATIVE COUPLING REACTION, OXIDOREDUCTASE
3l4d:B (ASP192) to (PRO394) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM LEISHMANIA INFANTUM IN COMPLEX WITH FLUCONAZOLE | STEROL 14-ALPHA DEMETHYLASE, CYP51, P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, ENDOPLASMIC RETICULUM, TRANSMEMBRANE PROTEIN, STEROL BIOSYNTHESIS, OBTUSIFOLIOL, LIPIDS, MEMBRANE, IRON
3l4d:D (ILE208) to (PHE415) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM LEISHMANIA INFANTUM IN COMPLEX WITH FLUCONAZOLE | STEROL 14-ALPHA DEMETHYLASE, CYP51, P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, ENDOPLASMIC RETICULUM, TRANSMEMBRANE PROTEIN, STEROL BIOSYNTHESIS, OBTUSIFOLIOL, LIPIDS, MEMBRANE, IRON
3lc4:A (ASP193) to (LEU455) HUMAN CYTOCHROME P450 2E1 IN COMPLEX WITH OMEGA-IMIDAZOLYL-DODECANOIC ACID | CYP2E1, P450 2E1, MONOOXYGENASE, ACETAMINOPHEN, HEME, ENDOPLASMIC RETICULUM, IRON, MEMBRANE, METAL-BINDING, MICROSOME, OXIDOREDUCTASE
3ld6:A (ASN220) to (TRP415) CRYSTAL STRUCTURE OF HUMAN LANOSTEROL 14ALPHA-DEMETHYLASE (CYP51) IN COMPLEX WITH KETOCONAZOLE | CYTOCHROME P450, STEROL 14ALPHA-DEMETHYLASE, KETOCONAZOLE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, ALTERNATIVE SPLICING, CHOLESTEROL BIOSYNTHESIS, ENDOPLASMIC RETICULUM, HEME, IRON, LIPID SYNTHESIS, MEMBRANE, METAL-BINDING, MICROSOME, MONOOXYGENASE, NADP, OXIDOREDUCTASE, POLYMORPHISM, STEROID BIOSYNTHESIS, STEROL BIOSYNTHESIS, TRANSMEMBRANE
3ld6:B (ASN220) to (LEU469) CRYSTAL STRUCTURE OF HUMAN LANOSTEROL 14ALPHA-DEMETHYLASE (CYP51) IN COMPLEX WITH KETOCONAZOLE | CYTOCHROME P450, STEROL 14ALPHA-DEMETHYLASE, KETOCONAZOLE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, ALTERNATIVE SPLICING, CHOLESTEROL BIOSYNTHESIS, ENDOPLASMIC RETICULUM, HEME, IRON, LIPID SYNTHESIS, MEMBRANE, METAL-BINDING, MICROSOME, MONOOXYGENASE, NADP, OXIDOREDUCTASE, POLYMORPHISM, STEROID BIOSYNTHESIS, STEROL BIOSYNTHESIS, TRANSMEMBRANE
3awp:A (PHE169) to (TRP326) CYTOCHROME P450SP ALPHA (CYP152B1) MUTANT F288G | CYTOCHROME P450, PEROXYGENASE, OXIDOREDUCTASE
3awq:A (PHE169) to (ALA339) CYTOCHROME P450SP ALPHA (CYP152B1) MUTANT L78F | CYTOCHROME P450, PEROXYGENASE, OXIDOREDUCTASE
5eab:A (THR223) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 COMPLEXED WITH THE PLANT PATHOGEN INHIBITOR S-TEBUCONAZOLE | CYP51, S-TEBUCONAZOLE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX
5ead:A (TYR227) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 COMPLEXED WITH THE PLANT PATHOGEN INHIBITOR S-DESTHIO-PROTHIOCONAZOLE | CYP51, S-DESTHIO-PROTHIOCONAZOLE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX
5eae:A (TYR227) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 COMPLEXED WITH THE PLANT PATHOGEN INHIBITOR R-DESTHIO-PROTHIOCONAZOLE | CYP51, R-DESTHIO-PROTHIOCONAZOLE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX
5eaf:A (THR223) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 COMPLEXED WITH THE PLANT PATHOGEN INHIBITOR FLUQUINCONAZOLE | CYP51, FLUQUINCONAZOLE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX
5eaf:B (TYR227) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 COMPLEXED WITH THE PLANT PATHOGEN INHIBITOR FLUQUINCONAZOLE | CYP51, FLUQUINCONAZOLE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX
5eag:A (THR237) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 COMPLEXED WITH THE PLANT PATHOGEN INHIBITOR PROCHLORAZ | CYP51, PROCHLORAZ, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX
5eah:A (TYR227) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 COMPLEXED WITH THE PLANT PATHOGEN INHIBITOR DIFENOCONAZOLE | CYP51, DIFENOCONAZOLE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, RACEMIC MIXTURE, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX
3b98:A (LEU204) to (PHE442) CRYSTAL STRUCTURE OF ZEBRAFISH PROSTACYCLIN SYNTHASE (CYTOCHROME P450 8A1) | PROSTACYCLIN SYNTHASE, CYTOCHROME P450 8A1, CYP8A1, ISOMERASE
3b98:B (LEU204) to (LEU390) CRYSTAL STRUCTURE OF ZEBRAFISH PROSTACYCLIN SYNTHASE (CYTOCHROME P450 8A1) | PROSTACYCLIN SYNTHASE, CYTOCHROME P450 8A1, CYP8A1, ISOMERASE
3bdz:A (PRO160) to (ARG367) THE ROLE OF ASN 242 IN P450CIN | PROTEIN IN THE ABSENCE OF SUBSTRATE, UNKNOWN FUNCTION
5eqb:A (TYR227) to (THR490) CRYSTAL STRUCTURE OF LANOSTEROL 14-ALPHA DEMETHYLASE WITH INTACT TRANSMEMBRANE DOMAIN BOUND TO ITRACONAZOLE | STEROL ANTIFUNGAL MEMBRANE CYTOCHROME, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, CENTER FOR STRUCTURES OF MEMBRANE PROTEINS, CSMP, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5ese:A (ALA226) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) G73R MUTANT COMPLEXED WITH FLUCONAZOLE | CYP51, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, MUTATION, G73R
5esf:A (TYR227) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) G73E MUTANT COMPLEXED WITH FLUCONAZOLE | CYP51, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX, MUTATION, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5esi:A (TYR227) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) G73W MUTANT | CYP51, OXIDOREDUCTASE
5esj:A (TYR227) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) G464S MUTANT COMPLEXED WITH FLUCONAZOLE | CYP51, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5esl:A (THR237) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) T322I MUTANT COMPLEXED WITH ITRACONAZOLE | CYP51, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5esm:A (THR237) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) T322I MUTANT COMPLEXED WITH FLUCONAZOLE | CYP51, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5esn:A (THR237) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) T322I MUTANT STRUCTURE | CYP51, OXIDOREDUCTASE
4bjk:C (ILE209) to (PHE415) CYP51 OF TRYPANOSOMA BRUCEI BOUND TO (S)-N-(3-(1H-INDOL-3- YL)-1-OXO-1-(PYRIDIN-4-YLAMINO)PROPAN-2-YL)-3,3'-DIFLUORO-( 1,1'-BIPHENYL)-4-CARBOXAMIDE | OXIDOREDUCTASE, ERGOSTEROL BIOSYNTHESIS
4bjk:D (ILE209) to (PHE415) CYP51 OF TRYPANOSOMA BRUCEI BOUND TO (S)-N-(3-(1H-INDOL-3- YL)-1-OXO-1-(PYRIDIN-4-YLAMINO)PROPAN-2-YL)-3,3'-DIFLUORO-( 1,1'-BIPHENYL)-4-CARBOXAMIDE | OXIDOREDUCTASE, ERGOSTEROL BIOSYNTHESIS
5ex6:B (ARG181) to (LEU322) STRUCTURE OF P450 STAH FROM GLYCOPEPTIDE ANTIBIOTIC A47934 BIOSYNTHESIS | CYTOCHROME P450, MONOOXYGENASE, PHENOLIC COUPLING, GLYCOPEPTIDE ANTIBIOTIC BIOSYNTHESIS, OXIDOREDUCTASE
4bmm:C (MET215) to (PRO395) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- YLAMINO)PROPAN-2-YL)- 2',3,5'-TRIFLUORO-(1,1'-BIPHENYL)-4-CARBOXAMIDE | OXIDOREDUCTASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
3mzs:B (PRO190) to (PHE444) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP11A1 IN COMPLEX WITH 22- HYDROXY-CHOLESTEROL | CYP11A1, CYTOCHROME P450, MONOOXYGENASE, SIDE CHAIN CLEAVAGE ENZYME, CHOLESTEROL, CHOLESTEROL 20-22-DESMOLASE, STEROID METABOLISM, OXIDOREDUCTASE, HEME
3mzs:C (PRO190) to (ASN443) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP11A1 IN COMPLEX WITH 22- HYDROXY-CHOLESTEROL | CYP11A1, CYTOCHROME P450, MONOOXYGENASE, SIDE CHAIN CLEAVAGE ENZYME, CHOLESTEROL, CHOLESTEROL 20-22-DESMOLASE, STEROID METABOLISM, OXIDOREDUCTASE, HEME
4r21:B (GLU201) to (ARG460) ZEBRA FISH CYTOCHROME P450 17A2 WITH PROGESTERONE | CYTOCHROME P450 17A2, PROGESTERONE, P450 17A2, 17 (ALPHA)- HYDROXYLATION, STEROID BIOSYNTHESIS, ENZYME KINETICS, OXIDOREDUCTASE
4by0:A (ALA194) to (PHE415) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- YLAMINO)PROPAN-2-YL)-3,3'-DIFLUORO-(1,1'-BIPHENYL)-4- CARBOXAMIDE | OXIDOREDUCTASE, STEROL 14-DEMETHYLASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
3n9y:A (PRO189) to (PHE444) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH CHOLESTEROL | CYTOCHROME P450, CHOLESTEROL SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3n9y:B (PRO189) to (PHE444) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH CHOLESTEROL | CYTOCHROME P450, CHOLESTEROL SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3n9z:A (PRO212) to (PHE444) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH 22- HYDROXYCHOLESTEROL | CYTOCHROME P450, 22-HYDROXYCHOLESTEROL, CHOLESTEROL SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3n9z:B (PRO212) to (PHE444) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH 22- HYDROXYCHOLESTEROL | CYTOCHROME P450, 22-HYDROXYCHOLESTEROL, CHOLESTEROL SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3na0:A (PRO251) to (ASN482) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH 20,22- DIHYDROXYCHOLESTEROL | CYTOCHROME P450, 20,22-DIHYDROXYCHOLESTEROL, SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3na0:B (PRO228) to (PHE483) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH 20,22- DIHYDROXYCHOLESTEROL | CYTOCHROME P450, 20,22-DIHYDROXYCHOLESTEROL, SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3na1:B (PRO212) to (PHE444) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH 20- HYDROXYCHOLESTEROL | CYTOCHROME P450, 20-HYDROXYCHOLESTEROL, CHOLESTEROL SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
4c27:A (MET215) to (PRO395) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- 4-YLAMINO)PROPAN-2-YL)-2-FLUORO-4-(4-(4-(TRIFLUOROMETHYL) PHENYL)PIPERAZIN-1-YL)BENZAMIDE | OXIDOREDUCTASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
4c27:B (MET215) to (PRO395) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- 4-YLAMINO)PROPAN-2-YL)-2-FLUORO-4-(4-(4-(TRIFLUOROMETHYL) PHENYL)PIPERAZIN-1-YL)BENZAMIDE | OXIDOREDUCTASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
4coh:A (MET215) to (PRO395) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE SULFONAMIDE DERIVATIVE OF THE 4-AMINOPYRIDYL-BASED INHIBITOR | TRANSFERASE, CYP51, STEROL 14-DEMETHYLASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
3oft:A (PRO161) to (GLY365) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP101C1 | OXIDOREDUCTASE
3oft:B (THR178) to (MET366) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP101C1 | OXIDOREDUCTASE
3oft:C (ARG160) to (GLY365) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP101C1 | OXIDOREDUCTASE
3ofu:B (THR178) to (PHE318) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP101C1 | OXIDOREDUCTASE
3ofu:C (THR178) to (PHE318) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP101C1 | OXIDOREDUCTASE
3ofu:D (ARG160) to (GLY365) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP101C1 | OXIDOREDUCTASE
3ofu:F (THR178) to (PHE318) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP101C1 | OXIDOREDUCTASE
4tt5:A (ASP140) to (ARG337) CRYSTAL STRUCTURE OF CYP119 FROM SULFOLOBUS ACIDOCALDARIUS, COMPLEXED WITH 4-(4-BROMOPHENYL)-1H IMIDAZOLE | OXIDOREDUCTASE
4tuv:A (ASP140) to (ARG337) X-RAY CRYSTAL STRUCTURE OF CYP119 FROM SULFOLOBUS ACIDOCALDARIUS, COMPLEXED WITH 4-(4-CHLOROPHENYL)IMIDAZOLE | OXIDOREDUCTASE
4d78:A (LEU229) to (ASN462) CYTOCHROME P450 3A4 BOUND TO AN INHIBITOR | OXIDOREDUCTASE, MONOOXYGENASE, HUMAN CYP3A4, INHIBITORY COMPLEX
5hdi:B (TRP171) to (ARG406) STRUCTURAL CHARACTERIZATION OF CYP144A1, A MYCOBACTERIUM TUBERCULOSIS CYTOCHROME P450 | MONOOXYGENASE, CYTOCHROME P450, HEME-BINDING, OXIDOREDUCTASE
5hh3:C (GLN160) to (PHE363) OXYA FROM ACTINOPLANES TEICHOMYCETICUS | CYTOCHROME P450 MONOOXYGENASE, PHENOLIC COUPLING ENZYME, BIOSYNTHESIS OF GLYCOPEPTIDE ANTIBIOTICS, PEPTIDE CYCLASE, OXIDOREDUCTASE
3p3z:A (ASP162) to (ARG375) CRYSTAL STRUCTURE OF THE CYTOCHROME P450 MONOOXYGENASE AURH FROM STREPTOMYCES THIOLUTEUS IN COMPLEX WITH ANCYMIDOL | CYTOCHROME P450 MONOOXYGENASE, OXIDATION FROM DEOXYAUREOTHIN TO AUREOTHIN, OXIDOREDUCTASE
4dnj:A (ASN192) to (TRP336) THE CRYSTAL STRUCTURES OF 4-METHOXYBENZOATE BOUND CYP199A2 | OXIDOREDUCTASE
4dnz:A (ASN189) to (TRP333) THE CRYSTAL STRUCTURES OF CYP199A4 | CYTOCHROME P450, SECONDARY METABOLITES, BIOSYNTHESIS, TRANSPORT, CATABOLISM, OXIDOREDUCTASE
4dnz:D (ASN189) to (VAL379) THE CRYSTAL STRUCTURES OF CYP199A4 | CYTOCHROME P450, SECONDARY METABOLITES, BIOSYNTHESIS, TRANSPORT, CATABOLISM, OXIDOREDUCTASE
3p99:C (ASP193) to (SER442) STEROL 14ALPHA-DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH DELTA7-14ALPHA-METHYLENE-CYCLOPROPYL-DIHYDROLANOSTEROL | CYTOCHROME P450 FOLD/STEROL 14-ALPHA DEMETHYLASE, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, HEMOPROTEIN, STEROL BIOSYNTHESIS, CYTOCHROME P450 REDUCTASE (CPR), ENDOPLASMIC RETICULUM, MEMBRANE
5hs1:A (TYR227) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) COMPLEXED WITH VORICONAZOLE | VORICONAZOLE, CYP51, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX, RESISTANCE MUTATION, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4uhl:A (ASN220) to (TRP415) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhl:B (ASN220) to (TRP415) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhl:C (GLU221) to (TRP415) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhl:D (ASN220) to (TRP415) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhl:E (ASN220) to (TRP415) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhl:F (ASN220) to (TRP415) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhl:G (ASN220) to (TRP415) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhl:H (ASN220) to (TRP415) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4dvq:A (PRO241) to (HIS470) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, CORTICOSTEROID, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE
4dvq:B (SER245) to (HIS470) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, CORTICOSTEROID, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE
4dvq:D (PRO241) to (HIS470) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, CORTICOSTEROID, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE
4dvq:E (PRO241) to (HIS470) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, CORTICOSTEROID, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE
4dvq:F (PRO241) to (HIS470) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, CORTICOSTEROID, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE
4dvq:G (PRO241) to (HIS470) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, CORTICOSTEROID, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE
4dvq:H (PRO241) to (ASP430) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, CORTICOSTEROID, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE
4uvr:A (PRO216) to (PHE415) BINDING MODE, SELECTIVITY AND POTENCY OF N-INDOLYL- OXOPYRIDINYL-4-AMINO-PROPANYL-BASED INHIBITORS TARGETING TRYPANOSOMA CRUZI CYP51 | OXIDOREDUCTASE, CYP51, STEROL 14-DEMETHYLASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
5ik1:A (PRO170) to (ARG377) OPEN STATE OF P450CAM AFTER SOAKING IN CAMPHOR | CONFORMATIONAL STATE, STRUCTURAL CHANGE, CRYSTAL CONTACT, OXIDOREDUCTASE
5it1:B (PRO158) to (PRO370) STREPTOMYCES PEUCETIUS CYP105P2 COMPLEX WITH BIPHENYL COMPOUND | CYP105P2-BIPHENYL COMPOUND COMPLEX, OXIDOREDUCTASE
5it1:D (PRO158) to (PRO370) STREPTOMYCES PEUCETIUS CYP105P2 COMPLEX WITH BIPHENYL COMPOUND | CYP105P2-BIPHENYL COMPOUND COMPLEX, OXIDOREDUCTASE
4uyl:B (ASP226) to (LEU483) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51B) FROM A PATHOGENIC FILAMENTOUS FUNGUS ASPERGILLUS FUMIGATUS IN COMPLEX WITH VNI | CYTOCHROME P450, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4uym:B (PHE218) to (PRO414) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51B) FROM A PATHOGENIC FILAMENTOUS FUNGUS ASPERGILLUS FUMIGATUS IN COMPLEX WITH VORICONAZOLE | CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE,
4fdh:H (PRO241) to (PHE471) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH FADROZOLE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, INHIBITOR, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3r9c:A (GLU170) to (VAL341) CRYSTAL STRUCTURE OF MYCOBACTERIUM SMEGMATIS CYP164A2 WITH ECONAZOLE BOUND | CYTOCHROME P450, MONOOXYGENASE, OXIDOREDUCTASE
4g7g:A (ILE209) to (PHE415) STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH THE VNI DERIVATIVE (R)-N-(1-(3,4'-DIFLUOROBIPHENYL-4-YL)-2-(1H- IMIDAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)BENZAMIDE [VNI/VNF (VFV)] | CYTOCHROME P450 FOLD, HEME, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANE BIOGENESIS, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4ggv:A (SER171) to (PHE367) CRYSTAL STRUCTURE OF HMTT INVOLVED IN HIMASTATIN BIOSYNTHESIS | CYSTEINE-LIGAND LOOP, HYDROLASE, OXIDOREDUCTASE
5l1p:A (GLN165) to (PHE321) X-RAY STRUCTURE OF CYTOCHROME P450 PNTM WITH PENTALENOLACTONE | PNTM, CYTOCHROME P450, PENTALENOLACTONE, OXIDOREDUCTASE
5l1r:A (GLN165) to (PHE321) X-RAY STRUCTURE OF THE SUBSTRATE-FREE CYTOCHROME P450 PNTM | PNTM, CYTOCHROME P450, BICINE, OXIDOREDUCTASE
5l1u:A (GLN165) to (PHE321) X-RAY STRUCTURE OF M81A MUTANT OF CYTOCHROME P450 PNTM WITH PENTALENOLACTONE F | PNTM, CYTOCHROME P450, PENTALENOLACTONE F, MUTANT, M81A, OXIDOREDUCTASE
2q6n:B (SER211) to (PHE457) STRUCTURE OF CYTOCHROME P450 2B4 WITH BOUND 1-(4- CHOLOROPHENYL)IMIDAZOLE | P450, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2
1f26:A (LEU164) to (GLU326) CRYSTAL STRUCTURE OF NO COMPLEX OF THR243VAL MUTANTS OF CYTOCHROME P450NOR | NITRIC OXIDE REDUCTASE, CYTOCHROME P450NOR, OXIDOREDUCTASE
3tzo:A (PRO164) to (ARG373) THE ROLE OF I87 OF CYP158A2 IN OXIDATIVE COUPLING REACTION | CYP158A2, PHENOLIC COUPLING REACTION, P450, MONOOXYGENASE, OXIDOREDUCTASE
3tzo:B (ARG168) to (ARG373) THE ROLE OF I87 OF CYP158A2 IN OXIDATIVE COUPLING REACTION | CYP158A2, PHENOLIC COUPLING REACTION, P450, MONOOXYGENASE, OXIDOREDUCTASE
4k9w:B (ILE230) to (ASP428) COMPLEX OF HUMAN CYP3A4 WITH A DESOXYRITONAVIR ANALOG | CYTOCHROME P450 3A4, ALPHA-BETA PROTEIN, CYTOCHROME P450 FOLD, MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4k9w:C (ILE230) to (TRP408) COMPLEX OF HUMAN CYP3A4 WITH A DESOXYRITONAVIR ANALOG | CYTOCHROME P450 3A4, ALPHA-BETA PROTEIN, CYTOCHROME P450 FOLD, MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4k9w:D (ILE230) to (TRP408) COMPLEX OF HUMAN CYP3A4 WITH A DESOXYRITONAVIR ANALOG | CYTOCHROME P450 3A4, ALPHA-BETA PROTEIN, CYTOCHROME P450 FOLD, MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
1smj:B (HIS171) to (GLU373) STRUCTURE OF THE A264E MUTANT OF CYTOCHROME P450 BM3 COMPLEXED WITH PALMITOLEATE | MONOOXYGENASE; FATTY ACID OXYGENASE; CYTOCHROME P450; SUBSTRATE BINDING; PALMITOLEATE, OXIDOREDUCTASE
3vm4:A (PHE169) to (ALA339) CYTOCHROME P450SP ALPHA (CYP152B1) IN COMPLEX WITH (R)-IBUPROPHEN | CYTOCHROME P450, OXIDOREDUCTASE
3voo:A (ASN160) to (ALA339) CYTOCHROME P450SP ALPHA (CYP152B1) MUTANT A245E | CYTOCHROME P450, OXIDOREDUCTASE
1io9:A (LYS141) to (HIS293) THERMOPHILIC CYTOCHROME P450 (CYP119) FROM SULFOLOBUS SOLFATARICUS: HIGH RESOLUTION STRUCTURAL ORIGIN OF ITS THERMOSTABILITY AND FUNCTIONAL PROPERTIES | THERMOPHILIC, CYTOCHROMO P450, CRYSTAL STRUCTURE, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, OXIDOREDUCTASE
2x5w:A (PRO186) to (HIS397) X-RAY STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS CYTOCHROME P450 CYP125 IN COMPLEX WITH SUBSTRATE CHOLEST-4-EN-3-ONE | CHOLESTEROL DEGRADATION, METAL-BINDING, OXIDOREDUCTASE
1jfb:A (LEU164) to (GLU326) X-RAY STRUCTURE OF NITRIC OXIDE REDUCTASE (CYTOCHROME P450NOR) IN THE FERRIC RESTING STATE AT ATOMIC RESOLUTION | NITRIC OXIDE REDUCTASE, CYTOCHROME P450NOR, ATOMIC RESOLUTION, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, OXIDOREDUCTASE
1w0f:A (PHE226) to (TRP408) CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 3A4 | OXIDOREDUCTASE, NIFEDIPINE OXIDASE, CYTOCHROME P450, ELECTRON TRANSPORT, MONOOXYGENASE
4nkx:B (PRO193) to (ARG462) HUMAN STEROIDOGENIC CYTOCHROME P450 17A1 MUTANT A105L WITH SUBSTRATE PROGESTERONE | HEME PROTEIN, MONOOXYGENASE, STEROID 17ALPHA-HYDROXYLASE, STEROID C17,20 LYASE, NADPH-CYTOCHROME P450 REDUCTASE, CYTOCHROME B5, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE, LYASE
1x8v:A (GLY163) to (ASN380) ESTRIOL-BOUND AND LIGAND-FREE STRUCTURES OF STEROL 14ALPHA- DEMETHYLASE (CYP51) | ALPHA-BETA, HEME CO-FACTOR, PROTEIN-ESTRIOL COMPLEX, OXIDOREDUCTASE
3jus:A (GLU221) to (TRP415) CRYSTAL STRUCTURE OF HUMAN LANOSTEROL 14ALPHA-DEMETHYLASE (CYP51) IN COMPLEX WITH ECONAZOLE | CYTOCHROME P450, STEROL 14ALPHA-DEMETHYLASE, ECONAZOLE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, CHOLESTEROL BIOSYNTHESIS, ENDOPLASMIC RETICULUM, HEME, IRON, LIPID SYNTHESIS, MEMBRANE, METAL-BINDING, MICROSOME, MONOOXYGENASE, NADP, OXIDOREDUCTASE, STEROID BIOSYNTHESIS, STEROL BIOSYNTHESIS, TRANSMEMBRANE
3jus:B (ASN220) to (TRP415) CRYSTAL STRUCTURE OF HUMAN LANOSTEROL 14ALPHA-DEMETHYLASE (CYP51) IN COMPLEX WITH ECONAZOLE | CYTOCHROME P450, STEROL 14ALPHA-DEMETHYLASE, ECONAZOLE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, CHOLESTEROL BIOSYNTHESIS, ENDOPLASMIC RETICULUM, HEME, IRON, LIPID SYNTHESIS, MEMBRANE, METAL-BINDING, MICROSOME, MONOOXYGENASE, NADP, OXIDOREDUCTASE, STEROID BIOSYNTHESIS, STEROL BIOSYNTHESIS, TRANSMEMBRANE
3awm:A (PHE169) to (ALA339) CYTOCHROME P450SP ALPHA (CYP152B1) WILD-TYPE WITH PALMITIC ACID | CYTOCHROME P450, PEROXYGENASE, OXIDOREDUCTASE
5eac:A (TYR227) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 COMPLEXED WITH THE PLANT PATHOGEN INHIBITOR R-TEBUCONAZOLE | CYP51, R-TEBUCONAZOLE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX
5esh:A (THR237) to (THR490) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) G73W MUTANT IN COMPLEX WITH ITRACONAZOLE | CYP51, MUTATION, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4r20:A (PRO200) to (ARG460) ZEBRA FISH CYTOCHROME P450 17A2 WITH ABIRATERONE | ABIRATERONE, ZEBRAFISH, P450 17A1, 17(ALPHA)-HYDROYLATION, LYSASE REACTION, STEROID BIOSYNTHESIS, ENZYME KINETICS, OXIDOREDUCTASE
4r20:B (GLN203) to (ARG460) ZEBRA FISH CYTOCHROME P450 17A2 WITH ABIRATERONE | ABIRATERONE, ZEBRAFISH, P450 17A1, 17(ALPHA)-HYDROYLATION, LYSASE REACTION, STEROID BIOSYNTHESIS, ENZYME KINETICS, OXIDOREDUCTASE
4cka:A (ASN193) to (PRO395) STEROL 14-ALPHA DEMETHYLASE (CYP51)FROM TRYPANOSOMA CRUZI IN COMPLEX WITH (S)-1-(4-FLUOROPHENYL)-2-(1H-IMIDAZOL-1-YL) ETHYL 4-ISOPROPYLPHENYLCARBAMATE (LFS) | HEME, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE
3p3o:A (ASP162) to (ARG375) CRYSTAL STRUCTURE OF THE CYTOCHROME P450 MONOOXYGENASE AURH (NTERMII) FROM STREPTOMYCES THIOLUTEUS | CYTOCHROME P450, MONOOXYGENASE, OXIDOREDUCTASE
4uhi:A (ASN220) to (TRP415) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN C121 SPACE GROUP | OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhi:B (ASN220) to (TRP415) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN C121 SPACE GROUP | OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhi:D (ASN220) to (TRP415) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN C121 SPACE GROUP | OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
5l1q:A (GLN165) to (PHE321) X-RAY STRUCTURE OF CYTOCHROME P450 PNTM WITH DIHYDROPENTALENOLACTONE F | PNTM, CYTOCHROME P450, DIHYDROPENTALENOLACTONE F, OXIDOREDUCTASE
5l1s:A (GLN165) to (PHE321) X-RAY STRUCTURE OF F232L MUTANT OF CYTOCHROME P450 PNTM WITH PENTALENOLACTONE F | PNTM, CYTOCHROME P450, PENTALENOLACTONE F, MUTANT, F232L, OXIDOREDUCTASE
5l1w:A (GLN165) to (PHE321) X-RAY STRUCTURE OF 2-MERCAPTOETHANOL MODIFIED M81C MUTANT OF CYTOCHROME P450 PNTM WITH PENTALENOLACTONE F | PNTM, CYTOCHROME P450, PENTALENOLACTONE F, MUTANT, M81C, 2- MERCAPTOETHANOL, OXIDOREDUCTASE
5liv:B (PRO218) to (GLY384) CRYSTAL STRUCTURE OF MYXOBACTERIAL CYP260A1 | 1-ALPHA-HYDROXYLASE, STEROID, SORANGIUM CELLULOSUM, REDOX POOL, OXIDOREDUCTASE