1n9b:A (ARG43) to (ASP213) ULTRAHIGH RESOLUTION STRUCTURE OF A CLASS A BETA-LACTAMASE: ON THE MECHANISM AND SPECIFICITY OF THE EXTENDED-SPECTRUM SHV-2 ENZYME | BETA-LACTAM HYDROLASE, PENICILLINASE, DETERGENT BINDING, DRUG DESIGN, RADIATION DAMAGE
3rxx:A (GLY54) to (ASN214) KPC-2 CARBAPENEMASE IN COMPLEX WITH 3-NPBA | INHIBITOR, BETA-LACTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2ov5:A (GLY42) to (ASN214) CRYSTAL STRUCTURE OF THE KPC-2 CARBAPENEMASE | CARBAPENEMASE, BETA-LACTAMASE, HYDROLASE
2ov5:B (GLY42) to (ASN214) CRYSTAL STRUCTURE OF THE KPC-2 CARBAPENEMASE | CARBAPENEMASE, BETA-LACTAMASE, HYDROLASE
2ov5:C (GLY42) to (ASN214) CRYSTAL STRUCTURE OF THE KPC-2 CARBAPENEMASE | CARBAPENEMASE, BETA-LACTAMASE, HYDROLASE
2b5r:A (ARG43) to (ALA213) 1B LACTAMASE / B LACTAMASE INHIBITOR | PROTEIN-PROTEIN COMPLEX, STRUCTURAL GENOMICS, ISRAEL STRUCTURAL PROTEOMICS CENTER, ISPC, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
2b5r:B (ALA42) to (ALA213) 1B LACTAMASE / B LACTAMASE INHIBITOR | PROTEIN-PROTEIN COMPLEX, STRUCTURAL GENOMICS, ISRAEL STRUCTURAL PROTEOMICS CENTER, ISPC, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
4h8r:B (GLN38) to (ASN209) IMIPENEM COMPLEX OF GES-5 CARBAPENEMASE | BETA-LACTAMASE, CARBAPENEMASE, CARBAPENEM ANTIBIOTICS, HYDROLASE- ANTIBIOTIC COMPLEX
1ny0:A (ARG43) to (ALA213) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN M182T MUTANT OF TEM-1 AND A BORONIC ACID INHIBITOR (NBF) | ANTIBIOTIC RESISTANCE, BETA-LACTAMASE, ACYLATION TRANSITION- STATE ANALOG, CRYSTAL STRUCTURE, HYDROLASE
1nym:A (LEU57) to (ALA213) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN M182T MUTANT OF TEM-1 AND A BORONIC ACID INHIBITOR (CXB) | ANTIBIOTIC RESISTANCE, BETA-LACTAMASE, ACYLATION TRANSITION- STATE ANALOG, CRYSTAL STRUCTURE, HYDROLASE
1nyy:A (LEU57) to (ASP214) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN M182T MUTANT OF TEM-1 AND A BORONIC ACID INHIBITOR (105) | ANTIBIOTIC RESISTANCE, BETA-LACTAMASE, ACYLATION TRANSITION- STATE ANALOG, CRYSTAL STRUCTURE, HYDROLASE
1bsg:A (GLY54) to (ASN214) BETA-LACTAMASE FROM STREPTOMYCES ALBUS G | HYDROLASE, ANTIBIOTIC RESISTANCE, PENICILLIN
1bt5:A (ALA42) to (ASP214) CRYSTAL STRUCTURE OF THE IMIPENEM INHIBITED TEM-1 BETA-LACTAMASE FROM ESCHERICHIA COLI | HYDROLASE, BETA-LACTAM DEGRADATION
1btl:A (ALA42) to (ASP214) CRYSTAL STRUCTURE OF ESCHERICHIA COLI TEM1 BETA-LACTAMASE AT 1.8 ANGSTROMS RESOLUTION | HYDROLASE
1bue:A (SER56) to (ASN214) NMC-A CARBAPENEMASE FROM ENTEROBACTER CLOACAE | HYDROLASE, ANTIBIOTIC RESISTANCE, CLASS A CARBAPENEMASE
1ong:A (ARG43) to (ASP213) SHV-1 BETA-LACTAMASE WITH A PENEM INHIBITOR | BETA-LACTAM HYDROLASE, PENICILLINASE, DETERGENT BINDING, DRUG DESIGN
1ck3:A (LEU57) to (ASP214) N276D MUTANT OF ESCHERICHIA COLI TEM-1 BETA-LACTAMASE | BETA-LACTAMASE, CLAVULANATE-RESISTANT, HYDROLASE
4ibr:A (LEU56) to (ALA212) CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 CARRYING G238S/E104K MUTATIONS | BETA-LACTAMASE, HYDROLASE
3g30:A (GLY42) to (ASN214) CTX-M-9 CLASS A BETA-LACTAMASE COMPLEXED WITH COMPOUND 3 (G30) | CTX-M, BETA-LACTAMASE, MOLECULAR DOCKING, FRAGMENT, INHIBITOR, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
2qpn:A (GLN38) to (GLY192) GES-1 BETA-LACTAMASE | BETA-LACTAMASE, APO-ENZYME, PLASMID, HYDROLASE
2qpn:B (GLN38) to (ASN209) GES-1 BETA-LACTAMASE | BETA-LACTAMASE, APO-ENZYME, PLASMID, HYDROLASE
1dy6:A (THR56) to (ASN214) STRUCTURE OF THE IMIPENEM-HYDROLYZING BETA-LACTAMASE SME-1 | HYDROLASE, LACTAMASE, ANTIBIOTIC, CARBAPENEM, IMIPENEM
1dy6:B (ASN55) to (ASN214) STRUCTURE OF THE IMIPENEM-HYDROLYZING BETA-LACTAMASE SME-1 | HYDROLASE, LACTAMASE, ANTIBIOTIC, CARBAPENEM, IMIPENEM
1q2p:A (ARG43) to (ASP213) SHV-1 CLASS A BETA-LACTAMASE COMPLEXED WITH PENEM WAY185229 | HYDROLASE, INHIBITION, BETA-LACTAM ANTIBIOTICS, DRUG DESIGN
3toi:A (ARG43) to (ASP214) TAILORING ENZYME STABILITY AND EXPLOITING STABILITY-TRAIT LINKAGE BY ITERATIVE TRUNCATION AND OPTIMIZATION | HYDROLASE
3toi:B (ALA42) to (ASP214) TAILORING ENZYME STABILITY AND EXPLOITING STABILITY-TRAIT LINKAGE BY ITERATIVE TRUNCATION AND OPTIMIZATION | HYDROLASE
3tsg:A (GLN38) to (ASN209) CRYSTAL STRUCTURE OF GES-14 | BETA LACTAMASE FOLD, HYDROLASE, BETA LACTAMS
3tsg:B (GLN38) to (ASN209) CRYSTAL STRUCTURE OF GES-14 | BETA LACTAMASE FOLD, HYDROLASE, BETA LACTAMS
1erm:A (ARG43) to (ALA213) X-RAY CRYSTAL STRUCTURE OF TEM-1 BETA LACTAMASE IN COMPLEX WITH A DESIGNED BORONIC ACID INHIBITOR (1R)-1-ACETAMIDO-2-(3-CARBOXYPHENYL) ETHANE BORONIC ACID | BETA-LACTAMASE, STRUCTURE-BASED DESIGN, BORONATE INHIBITOR, HYDROLASE
1ero:A (ARG43) to (ASP214) X-RAY CRYSTAL STRUCTURE OF TEM-1 BETA LACTAMASE IN COMPLEX WITH A DESIGNED BORONIC ACID INHIBITOR (1R)-2- PHENYLACETAMIDO-2-(3-CARBOXYPHENYL)ETHYL BORONIC ACID | BETA-LACTAMASE, STRUCTURE-BASED DESIGN, BORONATE INHIBITOR, HYDROLASE
1erq:A (ARG43) to (ASP214) X-RAY CRYSTAL STRUCTURE OF TEM-1 BETA LACTAMASE IN COMPLEX WITH A DESIGNED BORONIC ACID INHIBITOR (1R)-1-ACETAMIDO-2- (3-CARBOXY-2-HYDROXYPHENYL)ETHYL BORONIC ACID | BETA-LACTAMASE, STRUCTURE-BASED DESIGN, BORONATE INHIBITOR, HYDROLASE
1esu:A (ALA42) to (ASP214) S235A MUTANT OF TEM1 BETA-LACTAMASE | SERINE BETA-LACTAMASE, HYDROLASE, ANTIBIOTIC RESISTANCE
4jpm:A (ARG43) to (ASP213) STRUCTURE OF SHV-1 BETA-LACTAMASE IN COMPLEX WITH THE 7- ALKYLIDENECEPHALOSPORIN DCM-1-10 AT 1.14 ANG RESOLUTION | CLASS A BETA-LACTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2v1z:A (ARG20) to (ASP194) STRUCTURE OF A TEM-1 BETA-LACTAMASE INSERTANT ALLOSTERICALLY REGULATED BY KANAMYCIN AND ANIONS. | HYDROLASE, INSERTION MUTANT, ANTIBIOTIC RESISTANCE, ALLOSTERIC REGULATION
2v20:A (LEU37) to (ASP194) STRUCTURE OF A TEM-1 BETA-LACTAMASE INSERTANT ALLOSTERICALLY REGULATED BY KANAMYCIN AND ANIONS. COMPLEX WITH SULFATE. | HYDROLASE, INSERTION MUTANT, ANTIBIOTIC RESISTANCE, ALLOSTERIC REGULATION
1fqg:A (ALA42) to (ASP214) MOLECULAR STRUCTURE OF THE ACYL-ENZYME INTERMEDIATE IN TEM- 1 BETA-LACTAMASE | BETA-LACTAMASE, ACYL-ENZYME, PENICILLIN, CLASS A, HYDROLASE
3hre:A (GLY42) to (ASN214) X-RAY CRYSTALLOGRAPHIC STRUCTURE OF CTX-M-9 S70G | BETA-LACTAMASE, BLSE, CTX-M-9, ANTIBIOTIC RESISTANCE, HYDROLASE
4zam:A (ARG43) to (ASP213) CRYSTAL STRUCTURE OF SHV-1 BETA-LACTAMASE BOUND TO AVIBACTAM | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4zbe:A (GLY42) to (ASN213) CRYSTAL STRUCTURE OF KPC-2 BETA-LACTAMASE COMPLEXED WITH AVIBACTAM | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3v3r:A (GLN38) to (ASN209) CRYSTAL STRUCTURE OF GES-11 | BETA LACTAMASE FOLD, HYDROLASE, BETA LACTAMS
3v3r:B (GLN38) to (ASN209) CRYSTAL STRUCTURE OF GES-11 | BETA LACTAMASE FOLD, HYDROLASE, BETA LACTAMS
3v3s:A (GLN38) to (ASN209) CRYSTAL STRUCTURE OF GES-18 | BETA LACTAMASE FOLD, HYDROLASE, BETA LACTAMS
3v3s:B (GLN38) to (ASN209) CRYSTAL STRUCTURE OF GES-18 | BETA LACTAMASE FOLD, HYDROLASE, BETA LACTAMS
3v50:A (ARG43) to (ASP213) COMPLEX OF SHV S130G MUTANT BETA-LACTAMASE COMPLEXED TO SA2-13 | CLASS A BETA-LACTAMASE FOLD, HYDROLYZE B-LACTAM ANTIBIOTICS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3v5m:A (ARG43) to (ASP213) CRYSTAL STRUCTURE OF M69V MUTANT OF SHV BETA-LACTAMASE | CLASS A BETA-LACTAMASE FOLD, HYDROLYZE B-LACTAM ANTIBIOTICS, HYDROLASE
4zj1:A (LEU57) to (ASP214) CRYSTAL STRUCTURE OF P-ACRYLAMIDO-PHENYLALANINE MODIFIED TEM1 BETA- LACTAMASE FROM ESCHERICHIA COLI : V216ACRF MUTANT | NONCANONICAL AMINO ACID, BETA-LACTAMASE, PROTEIN EVOLUTION, EVOLUTIONARY ADVANTAGE, HYDROLASE
4zj2:A (LEU57) to (ASP214) CRYSTAL STRUCTURE OF P-ACRYLAMIDO-PHENYLALANINE MODIFIED TEM1 BETA- LACTAMASE FROM ESCHERICHIA COLI :E166N MUTANT | NONCANONICAL AMINO ACID, BETA-LACTAMASE, PROTEIN EVOLUTION, EVOLUTIONARY ADVANTAGE, HYDROLASE
4zj3:A (LEU57) to (ALA213) CRYSTAL STRUCTURE OF CEPHALEXIN BOUND ACYL-ENZYME INTERMEDIATE OF VAL216ACRF MUTANT TEM1 BETA-LACTAMASE FROM ESCHERICHIA COLI: E166N AND V216ACRF MUTANT. | NONCANONICAL AMINO ACID, BETA-LACTAMASE, PROTEIN EVOLUTION, EVOLUTIONARY ADVANTAGE, HYDROLASE
1tdg:A (ARG43) to (ASP213) COMPLEX OF S130G SHV-1 BETA-LACTAMASE WITH TAZOBACTAM | S130G SHV-1 CLASS A BETA-LACTAMASE, PENICILLINASE, BETA- LACTAM HYDROLASE, DETERGENT BINDING, INHIBITOR COMPLEX, TAZOBACTAM, ALDEHYDE, CYMAL-6
1tem:A (ALA42) to (ASP214) 6 ALPHA HYDROXYMETHYL PENICILLOIC ACID ACYLATED ON THE TEM- 1 BETA-LACTAMASE FROM ESCHERICHIA COLI | HYDROLASE, ANTIBIOTIC RESISTANCE, TRANSPOSABLE ELEMENT
2h5s:A (ARG43) to (ASP213) SA2-13 PENAM SULFONE COMPLEXED TO WT SHV-1 BETA-LACTAMASE | BETA-LACTAMASE INHIBITOR, DRUG DESIGN, HYDROLASE
1htz:A (ARG43) to (ASP214) CRYSTAL STRUCTURE OF TEM52 BETA-LACTAMASE | MUTANT FORM OF BETA-LACTAMASE, HYDROLASE
1htz:B (ARG43) to (ALA213) CRYSTAL STRUCTURE OF TEM52 BETA-LACTAMASE | MUTANT FORM OF BETA-LACTAMASE, HYDROLASE
1htz:C (ARG43) to (ALA213) CRYSTAL STRUCTURE OF TEM52 BETA-LACTAMASE | MUTANT FORM OF BETA-LACTAMASE, HYDROLASE
1htz:D (ARG43) to (ALA213) CRYSTAL STRUCTURE OF TEM52 BETA-LACTAMASE | MUTANT FORM OF BETA-LACTAMASE, HYDROLASE
1htz:E (ARG43) to (ALA213) CRYSTAL STRUCTURE OF TEM52 BETA-LACTAMASE | MUTANT FORM OF BETA-LACTAMASE, HYDROLASE
1hzo:A (ASN54) to (ASN214) STRUCTURE OF CLASS A CEPHALOSPORINASE FROM PROTEUS VULGARIS K1 | MIXED ALPHA/BETA, CEPHALOSPORINASE, CLASS A BETA-LACTAMASE, HYDROLASE
1hzo:B (GLY42) to (ASN214) STRUCTURE OF CLASS A CEPHALOSPORINASE FROM PROTEUS VULGARIS K1 | MIXED ALPHA/BETA, CEPHALOSPORINASE, CLASS A BETA-LACTAMASE, HYDROLASE
3w4q:A (GLY43) to (ASN214) CRYSTAL STRUCTURE OF PENA BETA-LACTAMASE FROM BURKHOLDERIA MULTIVORANS AT PH4.2 | BETA-LACTAMASE, HYDROLASE
3w4q:B (GLY43) to (ASN214) CRYSTAL STRUCTURE OF PENA BETA-LACTAMASE FROM BURKHOLDERIA MULTIVORANS AT PH4.2 | BETA-LACTAMASE, HYDROLASE
3w4q:C (GLY43) to (ASN214) CRYSTAL STRUCTURE OF PENA BETA-LACTAMASE FROM BURKHOLDERIA MULTIVORANS AT PH4.2 | BETA-LACTAMASE, HYDROLASE
4mez:A (ALA42) to (ALA213) CRYSTAL STRUCTURE OF M68L/M69T DOUBLE MUTANT TEM-1 | HYDROLASE
4mez:B (LEU57) to (ALA213) CRYSTAL STRUCTURE OF M68L/M69T DOUBLE MUTANT TEM-1 | HYDROLASE
2x71:B (ARG55) to (ASN214) STRUCTURAL BASIS FOR THE INTERACTION OF LACTIVICINS WITH SERINE BETA-LACTAMASES | HYDROLASE-ANTIBIOTIC COMPLEX, ANTIBIOTIC
5aq7:A (ARG173) to (ASP344) DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY | CHAPERONE, CRYSTALLIZATION CHAPERONE, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), RIGID DOMAIN FUSION
5aq7:B (ALA172) to (ALA343) DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY | CHAPERONE, CRYSTALLIZATION CHAPERONE, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), RIGID DOMAIN FUSION
5aq8:A (ARG181) to (ASP352) DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY | CHAPERONE, CRYSTALLIZATION CHAPERONE, DESIGNED ANKYRIN REPEAT PROTEIN ( DARPIN), RIGID DOMAIN FUSION
5aqa:A (ARG173) to (ASP344) DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY | CHAPERONE, CRYSTALLIZATION CHAPERONE, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), RIGID DOMAIN FUSION
5aqb:A (ALA182) to (ASP354) DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY | CHAPERONE, CRYSTALLIZATION CHAPERONE, DESIGNED ANKYRIN REPEAT PROTEIN ( DARPIN), RIGID DOMAIN FUSION
1vm1:A (LEU57) to (ASP214) STRUCTURE OF SHV-1 BETA-LACTAMASE INHIBITED BY TAZOBACTAM | BETA-LACTAMASE, BETA-LACTAM HYDROLASE, PENICILLINASE, DETERGENT BINDING, INHIBITOR DESIGN
1jtd:A (ARG43) to (ALA213) CRYSTAL STRUCTURE OF BETA-LACTAMASE INHIBITOR PROTEIN-II IN COMPLEX WITH TEM-1 BETA-LACTAMASE | PROTEIN-PROTEIN COMPLEX, TEM-1 BETA-LACTAMASE, BETA- LACTAMASE INHIBITOR PROTEIN-II, BLIP-II, HYDROLASE/INHIBITOR COMPLEX
1jvj:A (LEU57) to (ALA213) CRYSTAL STRUCTURE OF N132A MUTANT OF TEM-1 BETA-LACTAMASE IN COMPLEX WITH A N-FORMIMIDOYL-THIENAMYCINE | PROTEIN STABILITY, TEM-1, BETA-LACTAMASE, BETA-LACTAM, ANTIBIOTIC RESISTANCE, IMIPENEM, HYDROLASE
1jwp:A (ARG43) to (ASP214) STRUCTURE OF M182T MUTANT OF TEM-1 BETA-LACTAMASE | PROTEIN STABILITY, TEM-1, BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, EVOLUTION, HYDROLASE
1jwv:A (LEU57) to (ASP214) CRYSTAL STRUCTURE OF G238A MUTANT OF TEM-1 BETA-LACTAMASE IN COMPLEX WITH A BORONIC ACID INHIBITOR (SEFB4) | TEM-1, BETA-LACTAMASE, SERINE HYDROLASE, CRYSTAL STRUCTURE
1jwz:A (ARG43) to (ALA213) CRYSTAL STRUCTURE OF TEM-64 BETA-LACTAMASE IN COMPLEX WITH A BORONIC ACID INHIBITOR (105) | TEM-64, BETA-LACTAMASE, SERINE HYDROLASE, CRYSTAL STRUCTURE, EVOLUTION, ANTIBIOTIC RESISTANCE
3jyi:A (ARG43) to (ALA213) STRUCTURAL AND BIOCHEMICAL EVIDENCE THAT A TEM-1 {BETA}- LACTAMASE ASN170GLY ACTIVE SITE MUTANT ACTS VIA SUBSTRATE- ASSISTED CATALYSIS | BETA-LACTAMASE, ENZYME, ANTIBIOTIC RESISTANCE, DISULFIDE BOND, HYDROLASE, PLASMID, TRANSPOSABLE ELEMENT
3jyi:B (LEU57) to (ALA213) STRUCTURAL AND BIOCHEMICAL EVIDENCE THAT A TEM-1 {BETA}- LACTAMASE ASN170GLY ACTIVE SITE MUTANT ACTS VIA SUBSTRATE- ASSISTED CATALYSIS | BETA-LACTAMASE, ENZYME, ANTIBIOTIC RESISTANCE, DISULFIDE BOND, HYDROLASE, PLASMID, TRANSPOSABLE ELEMENT
3jyi:C (LEU57) to (ALA213) STRUCTURAL AND BIOCHEMICAL EVIDENCE THAT A TEM-1 {BETA}- LACTAMASE ASN170GLY ACTIVE SITE MUTANT ACTS VIA SUBSTRATE- ASSISTED CATALYSIS | BETA-LACTAMASE, ENZYME, ANTIBIOTIC RESISTANCE, DISULFIDE BOND, HYDROLASE, PLASMID, TRANSPOSABLE ELEMENT
3jyi:D (LEU57) to (ALA213) STRUCTURAL AND BIOCHEMICAL EVIDENCE THAT A TEM-1 {BETA}- LACTAMASE ASN170GLY ACTIVE SITE MUTANT ACTS VIA SUBSTRATE- ASSISTED CATALYSIS | BETA-LACTAMASE, ENZYME, ANTIBIOTIC RESISTANCE, DISULFIDE BOND, HYDROLASE, PLASMID, TRANSPOSABLE ELEMENT
3jyi:E (LEU57) to (ALA213) STRUCTURAL AND BIOCHEMICAL EVIDENCE THAT A TEM-1 {BETA}- LACTAMASE ASN170GLY ACTIVE SITE MUTANT ACTS VIA SUBSTRATE- ASSISTED CATALYSIS | BETA-LACTAMASE, ENZYME, ANTIBIOTIC RESISTANCE, DISULFIDE BOND, HYDROLASE, PLASMID, TRANSPOSABLE ELEMENT
3jyi:F (LEU57) to (ALA213) STRUCTURAL AND BIOCHEMICAL EVIDENCE THAT A TEM-1 {BETA}- LACTAMASE ASN170GLY ACTIVE SITE MUTANT ACTS VIA SUBSTRATE- ASSISTED CATALYSIS | BETA-LACTAMASE, ENZYME, ANTIBIOTIC RESISTANCE, DISULFIDE BOND, HYDROLASE, PLASMID, TRANSPOSABLE ELEMENT
1lhy:A (ALA42) to (ASP214) CRYSTAL STRUCTURE OF TEM-30 BETA-LACTAMASE AT 2.0 ANGSTROM | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, X-RAY STRUCTURE, TEM- 30, HYDROLASE
1li0:A (LEU57) to (ALA213) CRYSTAL STRUCTURE OF TEM-32 BETA-LACTAMASE AT 1.6 ANGSTROM | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, X-RAY STRUCTURE, TEM- 32, HYDROLASE
1li9:A (LEU57) to (ALA213) CRYSTAL STRUCTURE OF TEM-34 BETA-LACTAMASE AT 1.5 ANGSTROM | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, X-RAY STRUCTURE, TEM- 34, HYDROLASE
4a5r:B (ARG55) to (ASN214) CRYSTAL STRUCTURE OF CLASS A BETA-LACTAMASE FROM BACILLUS LICHENIFORMIS BS3 WITH TAZOBACTAM | HYDROLASE
2zd8:A (ARG43) to (ASP213) SHV-1 CLASS A BETA-LACTAMASE COMPLEXED WITH MEROPENEM | HYDROLASE, INHIBITOR, BETA-LACTAM ANTIBIOTICS, ANTIBIOTIC RESISTANCE
1xpb:A (ALA42) to (ASP214) STRUCTURE OF BETA-LACTAMASE TEM1 | HYDROLASE, ANTIBIOTIC RESISTANCE, TRANSPOSABLE ELEMENT, SIGNAL
1m40:A (LEU57) to (ALA213) ULTRA HIGH RESOLUTION CRYSTAL STRUCTURE OF TEM-1 | BETA-LACTAMASE, ACYLATION MECHANISM, X-RAY STRUCTURE, ULTRA- HIGH RESOLUTION, HYDROLASE
4op8:A (LEU56) to (ALA212) ROOM TEMPERATURE CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 CARRYING G238S MUTATION | BETA-LACTAMASE, HYDROLASE
4op5:A (LEU56) to (ASP213) CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 CARRYING R164S MUTATION | BETA-LACTAMASE, HYDROLASE
4opq:A (LEU56) to (ASP213) ROOM TEMPERATURE CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 CARRYING R164S/G238S MUTATIONS | BETA-LACTAMASE, HYDROLASE
4opr:A (LEU56) to (ASP213) CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 CARRYING G238S MUTATION | BETA-LACTAMASE, HYDROLASE
4opz:A (ARG42) to (ASP213) CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 CARRYING G238S MUTATION IN COMPLEX WITH BORON-BASED INHIBITOR EC25 | BETA-LACTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4oqg:A (LEU57) to (ASP214) CRYSTAL STRUCTURE OF TEM-1 BETA-LACTAMASE IN COMPLEX WITH BORON-BASED INHIBITOR EC25 | BETA-LACTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4oqg:B (ARG43) to (ALA213) CRYSTAL STRUCTURE OF TEM-1 BETA-LACTAMASE IN COMPLEX WITH BORON-BASED INHIBITOR EC25 | BETA-LACTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4oqg:C (ALA42) to (ASP214) CRYSTAL STRUCTURE OF TEM-1 BETA-LACTAMASE IN COMPLEX WITH BORON-BASED INHIBITOR EC25 | BETA-LACTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4oqg:D (ARG43) to (ASP214) CRYSTAL STRUCTURE OF TEM-1 BETA-LACTAMASE IN COMPLEX WITH BORON-BASED INHIBITOR EC25 | BETA-LACTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4oqg:E (LEU57) to (ASP214) CRYSTAL STRUCTURE OF TEM-1 BETA-LACTAMASE IN COMPLEX WITH BORON-BASED INHIBITOR EC25 | BETA-LACTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4oqg:F (LEU57) to (ASP214) CRYSTAL STRUCTURE OF TEM-1 BETA-LACTAMASE IN COMPLEX WITH BORON-BASED INHIBITOR EC25 | BETA-LACTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4oqi:A (ARG42) to (ASP213) CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 CARRYING R164S/G238S MUTATIONS | BETA-LCTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1xxm:A (ALA42) to (ALA213) THE MODULAR ARCHITECTURE OF PROTEIN-PROTEIN BINDING SITE | PROTEIN-PROTEIN COMPLEX; TEM-1 BETA-LACTAMASE; BETA-2 LACTAMASE INHIBITOR PROTEIN; BLIP, ISRAEL STRUCTURAL PROTEOMICS CENTER, ISPC, STRUCTURAL GENOMICS, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1yt4:A (LEU57) to (ALA213) CRYSTAL STRUCTURE OF TEM-76 BETA-LACTAMASE AT 1.4 ANGSTROM RESOLUTION | TEM-1, BETA-LACTAMASE, INHIBITOR RESISTANCE, IRT, S130G, HYDROLASE
1zg4:A (ALA42) to (ASP214) TEM1 BETA LACTAMASE | HYDROLASE
1zg6:A (ARG43) to (ALA213) TEM1 BETA LACTAMASE MUTANT S70G | HYDROLASE
3ly4:A (VAL57) to (ASN214) CRYSTAL STRUCTURE OF FLUOROPHORE-LABELED CLASS A -LACTAMASE PENP- E166CB IN COMPLEX WITH PENICILLIN G | BETA-LACTAMASE, FLUOROPHORE, BIOSENSOR, HYDROLASE, ANTIBIOTIC RESISTANCE, CELL MEMBRANE, LIPOPROTEIN, MEMBRANE, PALMITATE
5ee8:A (ARG43) to (ASP213) CRYSTAL STRUCTURE OF S02030 BORONIC ACID INHIBITOR COMPLEXED TO SHV-1 BETA-LACTAMASE | TRANSITION STATE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5eec:A (GLY42) to (ASN214) CRYSTAL STRUCTURE OF KPC-2 BETA-LACTAMASE IN COMPLEX WITH THE S02030 BORONIC ACID INHIBITOR | TRANSITION STATE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5eec:B (GLY42) to (ASN214) CRYSTAL STRUCTURE OF KPC-2 BETA-LACTAMASE IN COMPLEX WITH THE S02030 BORONIC ACID INHIBITOR | TRANSITION STATE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4b88:A (GLY42) to (ASN214) ANCESTRAL (GNCA) BETA-LACTAMASE CLASS A | HYDROLASE, ANTIBIOTIC RESISTANCE
3mke:A (GLY42) to (ASP214) SHV-1 BETA-LACTAMASE COMPLEX WITH LP06 | BETA-LACTAMASE, BORONIC ACID TRANSITION STATE INHIBITOR, DRUG DESIGN, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5eph:A (ILE49) to (ASN207) CRYSTAL STRUCTURE OF EXTENDED-SPECTRUM BETA-LACTAMASE BEL-1 IN COMPLEX WITH IMIPENEM | HYDROLASE-ANTIBIOTIC COMPLEX, EXTENDED-SPECTRUM BETA-LACTAMASE, PSEUDOMONAS AERUGINOSA
5eph:B (ILE49) to (ASN207) CRYSTAL STRUCTURE OF EXTENDED-SPECTRUM BETA-LACTAMASE BEL-1 IN COMPLEX WITH IMIPENEM | HYDROLASE-ANTIBIOTIC COMPLEX, EXTENDED-SPECTRUM BETA-LACTAMASE, PSEUDOMONAS AERUGINOSA
5eph:C (LYS36) to (ASN207) CRYSTAL STRUCTURE OF EXTENDED-SPECTRUM BETA-LACTAMASE BEL-1 IN COMPLEX WITH IMIPENEM | HYDROLASE-ANTIBIOTIC COMPLEX, EXTENDED-SPECTRUM BETA-LACTAMASE, PSEUDOMONAS AERUGINOSA
5eph:D (ILE49) to (ASN207) CRYSTAL STRUCTURE OF EXTENDED-SPECTRUM BETA-LACTAMASE BEL-1 IN COMPLEX WITH IMIPENEM | HYDROLASE-ANTIBIOTIC COMPLEX, EXTENDED-SPECTRUM BETA-LACTAMASE, PSEUDOMONAS AERUGINOSA
4qu3:A (GLN38) to (GLY192) GES-2 ERTAPENEM ACYL-ENZYME COMPLEX | ANTIBIOTIC RESISTANCE, BETA-LACTAMASE, HYDROLASE, ERTAPENEM, HYDROLASE-ANTIBIOTIC COMPLEX
4qu3:B (GLN38) to (GLY192) GES-2 ERTAPENEM ACYL-ENZYME COMPLEX | ANTIBIOTIC RESISTANCE, BETA-LACTAMASE, HYDROLASE, ERTAPENEM, HYDROLASE-ANTIBIOTIC COMPLEX
5eua:A (LYS36) to (ASN207) CRYSTAL STRUCTURE OF EXTENDED-SPECTRUM BETA-LACTAMASE BEL-1 IN COMPLEX WITH MOXALACTAM | HYDROLASE-ANTIBIOTIC COMPLEX, EXTENDED-SPECTRUM BETA-LACTAMASE, PSEUDOMONAS AERUGINOSA, OXACEPHEM ANTIBIOTIC
5eua:B (ILE49) to (ASN207) CRYSTAL STRUCTURE OF EXTENDED-SPECTRUM BETA-LACTAMASE BEL-1 IN COMPLEX WITH MOXALACTAM | HYDROLASE-ANTIBIOTIC COMPLEX, EXTENDED-SPECTRUM BETA-LACTAMASE, PSEUDOMONAS AERUGINOSA, OXACEPHEM ANTIBIOTIC
4qy5:A (ARG43) to (MET211) CRYSTAL STRUCTURES OF CHIMERIC BETA-LACTAMASE CTEM-19M SHOWING DIFFERENT CONFORMATIONS | HYDROLASE
4qy6:A (ARG43) to (MET211) CRYSTAL STRUCTURES OF CHIMERIC BETA-LACTAMASE CTEM-19M SHOWING DIFFERENT CONFORMATIONS | HYDROLASE
3mxr:A (ARG43) to (ASP213) SHV-1 BETA-LACTAMASE COMPLEX WITH COMPOUND 1 | BETA-LACTAMASE, BORONIC ACID TRANSITION STATE INHIBITOR, DRUG DESIGN, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3mxs:A (ARG43) to (ASP213) SHV-1 BETA-LACTAMASE COMPLEX WITH COMPOUND 2 | BETA-LACTAMASE, BORONIC ACID TRANSITION STATE INHIBITOR, DRUG DESIGN, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5f82:A (GLN38) to (ASN209) APO GES-5 C69G MUTANT | HYDROLASE, CARBAPENEMASE, ANTIBIOTIC RESISTANCE
5f82:B (GLN38) to (ASN209) APO GES-5 C69G MUTANT | HYDROLASE, CARBAPENEMASE, ANTIBIOTIC RESISTANCE
5f83:A (GLN38) to (ASN209) IMIPENEM COMPLEX OF THE GES-5 C69G MUTANT | ANTIBIOTIC RESISTANCE, HYDROLASE, CARBAPENEMASE, IMIPENEM, MUTANT, HYDROLASE-ANTIBIOTIC COMPLEX
5f83:B (GLN38) to (ASN209) IMIPENEM COMPLEX OF THE GES-5 C69G MUTANT | ANTIBIOTIC RESISTANCE, HYDROLASE, CARBAPENEMASE, IMIPENEM, MUTANT, HYDROLASE-ANTIBIOTIC COMPLEX
3byd:A (GLY46) to (ASN217) CRYSTAL STRUCTURE OF BETA-LACTAMASE OXY-1-1 FROM KLEBSIELLA OXYTOCA | MULTI-DOMAIN PROTEINS (ALPHA AND BETA), ANTIBIOTIC RESISTANCE, HYDROLASE
4r3b:A (ARG43) to (ASP213) CRYSTAL STRUCTURE OF SHV-1 B-LACTAMASE IN COMPLEX WITH 6B- (HYDROXYMETHYL)PENICILLANIC ACID SULFONE PSR-283A | CLASS A BETA-LACTAMASE, HYDROLASE, INACTIVATE B-LACTAM ANTIBIOTICS
4r4s:A (ARG43) to (MET211) CRYSTAL STRUCTURE OF CHIMERIC BETA-LACTAMASE CTEM-19M AT 1.1 ANGSTROM RESOLUTION | HYDROLASE
3c4o:A (ARG43) to (ASP214) CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA- LACTAMASE INHIBITOR PROTEIN (BLIP) E73M/S130K/S146M COMPLEX | BETA-LACTAMASE, BETA-LACTAMASE INHIBITORY PROTEIN, PROTEIN- PROTEIN COMPLEX, BLIP, SHV-1, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, SECRETED, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3c4p:A (ARG43) to (ASP214) CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA- LACTAMASE INHIBITOR PROTEIN (BLIP) E73M COMPLEX | BETA-LACTAMASE, BETA-LACTAMASE INHIBITORY PROTEIN, PROTEIN- PROTEIN COMPLEX, BLIP, SHV-1, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, SECRETED, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3c7u:A (ALA42) to (ASP214) STRUCTURAL INSIGHT INTO THE KINETICS AND CP OF INTERACTIONS BETWEEN TEM-1-LACTAMASE AND BLIP | ENZYME-INHIBITOR COMPLEX, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, SECRETED, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3c7u:C (ALA42) to (ASP214) STRUCTURAL INSIGHT INTO THE KINETICS AND CP OF INTERACTIONS BETWEEN TEM-1-LACTAMASE AND BLIP | ENZYME-INHIBITOR COMPLEX, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, SECRETED, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3c7v:A (ARG43) to (ASP214) STRUCTURAL INSIGHT INTO THE KINETICS AND DELTA-CP OF INTERACTIONS BETWEEN TEM-1 BETA-LACTAMASE AND BLIP | ENZYME-INHIBITOR COMPLEX, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, SECRETED, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3c7v:C (LEU57) to (ASP214) STRUCTURAL INSIGHT INTO THE KINETICS AND DELTA-CP OF INTERACTIONS BETWEEN TEM-1 BETA-LACTAMASE AND BLIP | ENZYME-INHIBITOR COMPLEX, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, SECRETED, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3ni9:A (GLN38) to (ASN209) GES-2 CARBAPENEMASE APO FORM | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAPENEMASE, HYDROLASE
3ni9:B (GLN38) to (ASN209) GES-2 CARBAPENEMASE APO FORM | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAPENEMASE, HYDROLASE
3nia:A (GLN38) to (GLY192) GES-2 CARBAPENEMASE TAZOBACTAM COMPLEX | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAPENEMASE, LACTAMASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4c6y:A (GLY42) to (ASN214) ANCESTRAL PNCA (LAST COMMON ANCESTORS OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA) BETA-LACTAMASE CLASS A | HYDROLASE, ANTIBIOTIC RESISTANCE
4c6y:B (ARG43) to (ASN214) ANCESTRAL PNCA (LAST COMMON ANCESTORS OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA) BETA-LACTAMASE CLASS A | HYDROLASE, ANTIBIOTIC RESISTANCE
3cmz:A (ARG43) to (ASP214) TEM-1 CLASS-A BETA-LACTAMASE L201P MUTANT APO STRUCTURE | STABILIZATION MUTATION, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, TRANSPOSABLE ELEMENT
4rva:A (LEU57) to (ALA213) A TRIPLE MUTANT IN THE OMEGA-LOOP OF TEM-1 BETA-LACTAMASE CHANGES THE SUBSTRATE PROFILE VIA A LARGE CONFORMATIONAL CHANGE AND AN ALTERED GENERAL BASE FOR DEACYLATION | GLOBULAR, BETA-LACTAMASE, HYDROLASE
4rx2:A (ARG43) to (ALA213) A TRIPLE MUTANT IN THE OMEGA-LOOP OF TEM-1 BETA-LACTAMASE CHANGES THE SUBSTRATE PROFILE VIA A LARGE CONFORMATIONAL CHANGE AND AN ALTERED GENERAL BASE FOR CATALYSIS | GLOBULAR, BETA-LACTAMASE, HYDROLASE
4rx2:B (ARG43) to (ALA213) A TRIPLE MUTANT IN THE OMEGA-LOOP OF TEM-1 BETA-LACTAMASE CHANGES THE SUBSTRATE PROFILE VIA A LARGE CONFORMATIONAL CHANGE AND AN ALTERED GENERAL BASE FOR CATALYSIS | GLOBULAR, BETA-LACTAMASE, HYDROLASE
4rx2:C (ARG43) to (ALA213) A TRIPLE MUTANT IN THE OMEGA-LOOP OF TEM-1 BETA-LACTAMASE CHANGES THE SUBSTRATE PROFILE VIA A LARGE CONFORMATIONAL CHANGE AND AN ALTERED GENERAL BASE FOR CATALYSIS | GLOBULAR, BETA-LACTAMASE, HYDROLASE
4rx2:D (ARG43) to (ALA213) A TRIPLE MUTANT IN THE OMEGA-LOOP OF TEM-1 BETA-LACTAMASE CHANGES THE SUBSTRATE PROFILE VIA A LARGE CONFORMATIONAL CHANGE AND AN ALTERED GENERAL BASE FOR CATALYSIS | GLOBULAR, BETA-LACTAMASE, HYDROLASE
4rx2:F (ARG43) to (ALA213) A TRIPLE MUTANT IN THE OMEGA-LOOP OF TEM-1 BETA-LACTAMASE CHANGES THE SUBSTRATE PROFILE VIA A LARGE CONFORMATIONAL CHANGE AND AN ALTERED GENERAL BASE FOR CATALYSIS | GLOBULAR, BETA-LACTAMASE, HYDROLASE
4rx2:H (ARG43) to (ALA213) A TRIPLE MUTANT IN THE OMEGA-LOOP OF TEM-1 BETA-LACTAMASE CHANGES THE SUBSTRATE PROFILE VIA A LARGE CONFORMATIONAL CHANGE AND AN ALTERED GENERAL BASE FOR CATALYSIS | GLOBULAR, BETA-LACTAMASE, HYDROLASE
4rx3:A (LEU57) to (ALA213) A TRIPLE MUTANT IN THE OMEGA-LOOP OF TEM-1 BETA-LACTAMASE CHANGES THE SUBSTRATE PROFILE VIA A LARGE CONFORMATIONAL CHANGE AND AN ALTERED GENERAL BASE FOR CATALYSIS | GLOBULAR, BETA-LACTAMASE, HYDROLASE
3d4f:A (ARG43) to (ASP213) SHV-1 BETA-LACTAMASE COMPLEX WITH LN1-255 | BETA-LACTAMASE INHIBITOR, DRUG DESIGN, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID
3oph:A (ARG43) to (ASP214) ESBL R164S MUTANT OF SHV-1 BETA-LACTAMASE | CLASS A BETA-LACTAMASE, HYDROLASE
3opl:A (ARG43) to (ASP214) ESBL R164H MUTANT SHV-1 BETA-LACTAMASE | CLASS A BETA-LACTAMASE, HYDROLASE
3opr:A (ARG43) to (ASP213) ESBL R164H MUTANT OF SHV-1 BETA-LACTAMASE COMPLEXED TO SA2-13 | CLASS A BETA-LACTAMASE, HYDROLASE
3dtm:A (ARG43) to (ALA213) INCREASED FOLDING STABILITY OF TEM-1 BETA-LACTAMASE BY IN- VITRO SELECTION | TEM-1 BETA-LACTAMASE, HYDROLASE, ANTIBIOTIC RESISTANCE, PLASMID
3dw0:A (GLY42) to (ASN214) CRYSTAL STRUCTURE OF THE CLASS A CARBAPENEMASE KPC-2 AT 1.6 ANGSTROM RESOLUTION | BETA-LACTAMASE, KPC-2, CARBAPENEMASE, ANTIBIOTIC RESISTANCE, HYDROLASE
3dw0:B (GLY42) to (GLY213) CRYSTAL STRUCTURE OF THE CLASS A CARBAPENEMASE KPC-2 AT 1.6 ANGSTROM RESOLUTION | BETA-LACTAMASE, KPC-2, CARBAPENEMASE, ANTIBIOTIC RESISTANCE, HYDROLASE
3p09:A (GLY34) to (ASP205) CRYSTAL STRUCTURE OF BETA-LACTAMASE FROM FRANCISELLA TULARENSIS | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, ALPHA-BETA SANDWICH, CYTOSOL, HYDROLASE
3e2l:A (ALA55) to (ASN214) CRYSTAL STRUCTURE OF THE KPC-2 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) | BETA-LACTAMASE, BETA-LACTAMASE INHIBITOR PROTEIN, PROTEIN- PROTEIN COMPLEX, BLIP, KPC-2, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, SECRETED, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3e2l:B (GLY54) to (ASN214) CRYSTAL STRUCTURE OF THE KPC-2 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) | BETA-LACTAMASE, BETA-LACTAMASE INHIBITOR PROTEIN, PROTEIN- PROTEIN COMPLEX, BLIP, KPC-2, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, SECRETED, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3p98:A (ARG43) to (ASP214) THE CRYSTAL STRUCTURE OF THE EXTENDED SPECTRUM BETA-LACTAMASE TEM-72 REVEALS INHIBITION BY CITRATE | ABA-SANDWICH, BETA-LACTAMASE, HYDROLASE
3p98:B (ARG43) to (ASP214) THE CRYSTAL STRUCTURE OF THE EXTENDED SPECTRUM BETA-LACTAMASE TEM-72 REVEALS INHIBITION BY CITRATE | ABA-SANDWICH, BETA-LACTAMASE, HYDROLASE
5hx9:A (ARG44) to (MET211) CRYSTAL STRUCTURE OF BETA-LACTAMASE FROM BURKHOLDERIA VIETNAMIENSIS | SSGCID, BETA-LACTAMASE, BURKHOLDERIA VIETNAMIENSIS, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, HYDROLASE
4dxc:A (ALA398) to (GLY574) CRYSTAL STRUCTURE OF THE ENGINEERED MBP TEM-1 FUSION PROTEIN RG13, C2 SPACE GROUP | TEM, BETA-LACTAMASE, MBP, ALLOSTERIC REGULATION, ZINC BINDING, MALTOSE BINDING, SUGAR BINDING PROTEIN, HYDROLASE
4euz:A (GLY42) to (ASN214) CRYSTAL STRUCTURE OF SERRATIA FONTICOLA CARBAPENEMASE SFC-1 S70A- MEROPENEM COMPLEX | CARBAPENEMASE, HYDROLASE, ANTIBIOTIC RESISTANCE, BETA-LACTAMASE COMPLEX, HYDROLASE-ANTIBIOTIC COMPLEX
4fcf:A (ARG43) to (ASP213) K234R: APO STRUCTURE OF INHIBITOR RESISTANT BETA-LACTAMASE | CLASS A BETA-LACTAMSE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4fh2:A (LEU57) to (ASP213) STRUCTURE OF S70C BETA-LACTAMASE BOUND TO SULBACTAM | CLASS A BETA-LACTAMASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4gd6:A (ARG43) to (ASP213) SHV-1 BETA-LACTAMASE IN COMPLEX WITH PENAM SULFONE SA1-204 | CLASS A BETA-LACTAMASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4gd8:A (ARG43) to (ASP213) SHV-1 BETA-LACTAMASE IN COMPLEX WITH PENAM SULFONE SA3-53 | CLASS A BETA-LACTAMASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4gnu:A (GLN38) to (GLY192) CRYSTAL STRUCTURE OF GES-5 CARBAPENEMASE | BETA-LACTAMASE, CARBAPENEMASE, HYDROLASE
4gnu:B (GLN38) to (ASN209) CRYSTAL STRUCTURE OF GES-5 CARBAPENEMASE | BETA-LACTAMASE, CARBAPENEMASE, HYDROLASE
3rxw:A (GLY42) to (ASN213) KPC-2 CARBAPENEMASE IN COMPLEX WITH PSR3-226 | INHIBITOR, BETA-LACTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1axb:A (LEU57) to (ASP214) TEM-1 BETA-LACTAMASE FROM ESCHERICHIA COLI INHIBITED WITH AN ACYLATION TRANSITION STATE ANALOG | HYDROLASE, ANTIBIOTIC RESISTANCE, BETA-LACTAMASE
1nxy:A (ALA42) to (ALA213) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN M182T MUTANT OF TEM-1 AND A BORONIC ACID INHIBITOR (SM2) | ANTIBIOTIC RESISTANCE, BETA-LACTAMASE, DEACYLATION TRANSITION-STATE ANALOG, CRYSTAL STRUCTURE, HYDROLASE
4ibx:A (LEU57) to (ALA213) CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 | TEM-1 BETA-LACTAMASE, HYDROLASE
4ibx:B (LEU57) to (ALA213) CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 | TEM-1 BETA-LACTAMASE, HYDROLASE
4ibx:C (GLY42) to (ALA213) CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 | TEM-1 BETA-LACTAMASE, HYDROLASE
4ibx:D (GLY42) to (ALA213) CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 | TEM-1 BETA-LACTAMASE, HYDROLASE
4ibx:E (GLY42) to (GLY218) CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 | TEM-1 BETA-LACTAMASE, HYDROLASE
4id4:A (ALA42) to (GLU212) CRYSTAL STRUCTURE OF CHIMERIC BETA-LACTAMASE CTEM-17M | BETA-LACTAMASE, HYDROLASE
3gmw:A (LEU57) to (ASP214) CRYSTAL STRUCTURE OF BETA-LACTAMSE INHIBITORY PROTEIN-I (BLIP-I) IN COMPLEX WITH TEM-1 BETA-LACTAMASE | PROTEIN-PROTEIN COMPLEX, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, PROTEIN BINDING
3gmw:C (LEU57) to (ASP214) CRYSTAL STRUCTURE OF BETA-LACTAMSE INHIBITORY PROTEIN-I (BLIP-I) IN COMPLEX WITH TEM-1 BETA-LACTAMASE | PROTEIN-PROTEIN COMPLEX, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, PROTEIN BINDING
1pzo:A (ARG43) to (ASP214) TEM-1 BETA-LACTAMASE IN COMPLEX WITH A NOVEL, CORE- DISRUPTING, ALLOSTERIC INHIBITOR | BETA-LACTAMASE, NOVEL ALLOSTERIC INHIBITOR, CORE-DISRUPTION, CRYSTAL STRUCTURE, HYDROLASE
1pzp:A (ARG43) to (ASP214) TEM-1 BETA-LACTAMASE IN COMPLEX WITH A NOVEL, CORE- DISRUPTING, ALLOSTERIC INHIBITOR | BETA-LACTAMASE, NOVEL ALLOSTERIC INHIBITOR, CORE-DISRUPTION, CRYSTAL STRUCTURE, HYDROLASE
1tdl:A (ARG43) to (ASP213) STRUCTURE OF SER130GLY SHV-1 BETA-LACTAMASE | CLASS A BETA-LACTAMASE, PENICILLINASE, BETA-LACTAM HYDROLASE, DETERGENT BINDING, DRUG DESIGN
2wk0:B (ARG55) to (ASN214) CRYSTAL STRUCTURE OF THE CLASS A BETA-LACTAMASE BS3 INHIBITED BY 6-BETA-IODOPENICILLANATE. | HYDROLASE, BETA- LACTAMASE, IODOPENICILLANATE, ANTIBIOTIC RESISTANCE, BACILLUS LICHENIFORMIS
3w4o:A (GLY43) to (ASN214) CRYSTAL STRUCTURE OF PENI BETA-LACTAMASE FROM BURKHOLDERIA PSEUDOMALLEI AT PH9.5 | BETA-LACTAMASE, HYDROLASE
4mbf:A (ARG43) to (ASP213) CRYSTAL STRUCTURE OF PENAM SULFONE PSR-4-157 BOUND TO SHV-1 BETA- LACTAMASE | CLASS A BETA-LACTAMASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4mbk:A (ARG43) to (ASP213) CRYSTAL STRUCTURE OF K234R INHIBITOR-RESISTANT VARIANT OF SHV BETA- LACTAMASE IN COMPLEX WITH SA2-13 | CLASS A BETA-LACTAMASE, HYDROLASE
5aq9:A (ARG177) to (ASP348) DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY | CHAPERONE, CRYSTALLIZATION CHAPERONE, DESIGNED ANKYRIN REPEAT PROTEIN ( DARPIN), RIGID DOMAIN FUSION
5aq9:C (ARG177) to (ASP348) DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY | CHAPERONE, CRYSTALLIZATION CHAPERONE, DESIGNED ANKYRIN REPEAT PROTEIN ( DARPIN), RIGID DOMAIN FUSION
3zdj:A (GLY42) to (ASP214) ANCESTRAL (ENCA) BETA-LACTAMASE CLASS A | HYDROLASE, ANTIBIOTIC RESISTANCE
3zdj:B (ARG43) to (ALA213) ANCESTRAL (ENCA) BETA-LACTAMASE CLASS A | HYDROLASE, ANTIBIOTIC RESISTANCE
4opy:A (LEU56) to (ASP213) ROOM TEMPERATURE CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 CARRYING R164S MUTATION | BETA-LACTAMAS, HYDROLASE
4oq0:A (LEU56) to (ASP213) CRYSTAL STRUCTURE OF STABILIZED TEM-1 BETA-LACTAMASE VARIANT V.13 CARRYING R164S/G238S MUTATION IN COMPLEX WITH BORON-BASED INHIBITOR EC25 | BETA-LACTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5eoe:A (LYS36) to (ASN207) CRYSTAL STRUCTURE OF EXTENDED-SPECTRUM BETA-LACTAMASE BEL-1 (ORTHORHOMBIC FORM) | HYDROLASE, EXTENDED-SPECTRUM BETA-LACTAMASE, CITRATE, NATIVE, PSEUDOMONAS AERUGINOSA
5eoe:B (LYS36) to (ASN207) CRYSTAL STRUCTURE OF EXTENDED-SPECTRUM BETA-LACTAMASE BEL-1 (ORTHORHOMBIC FORM) | HYDROLASE, EXTENDED-SPECTRUM BETA-LACTAMASE, CITRATE, NATIVE, PSEUDOMONAS AERUGINOSA
3mkf:A (GLY42) to (ASP214) SHV-1 BETA-LACTAMASE COMPLEX WITH GB0301 | BETA-LACTAMASE, BORONIC ACID TRANSITION STATE INHIBITOR, DRUG DESIGN, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5eoo:A (LYS36) to (ASN207) CRYSTAL STRUCTURE OF EXTENDED-SPECTRUM BETA-LACTAMASE BEL-1 (MONOCLINIC FORM) | HYDROLASE, EXTENDED-SPECTRUM BETA-LACTAMASE, CITRATE, NATIVE, PSEUDOMONAS AERUGINOSA
5eoo:B (LYS36) to (ASN207) CRYSTAL STRUCTURE OF EXTENDED-SPECTRUM BETA-LACTAMASE BEL-1 (MONOCLINIC FORM) | HYDROLASE, EXTENDED-SPECTRUM BETA-LACTAMASE, CITRATE, NATIVE, PSEUDOMONAS AERUGINOSA
5eoo:C (LYS36) to (ASN207) CRYSTAL STRUCTURE OF EXTENDED-SPECTRUM BETA-LACTAMASE BEL-1 (MONOCLINIC FORM) | HYDROLASE, EXTENDED-SPECTRUM BETA-LACTAMASE, CITRATE, NATIVE, PSEUDOMONAS AERUGINOSA
5eoo:D (ILE49) to (ASN207) CRYSTAL STRUCTURE OF EXTENDED-SPECTRUM BETA-LACTAMASE BEL-1 (MONOCLINIC FORM) | HYDROLASE, EXTENDED-SPECTRUM BETA-LACTAMASE, CITRATE, NATIVE, PSEUDOMONAS AERUGINOSA
4r4r:A (ARG43) to (MET211) CRYSTAL STRUCTURE OF CHIMERIC BETA-LACTAMASE CTEM-19M AT 1.2 ANGSTROM RESOLUTION | HYDROLASE
4c75:A (GLY42) to (ASN214) CONSENSUS (ALL-CON) BETA-LACTAMASE CLASS A | HYDROLASE, ANTIBIOTIC RESISTANCE
4c75:B (GLY42) to (ASN214) CONSENSUS (ALL-CON) BETA-LACTAMASE CLASS A | HYDROLASE, ANTIBIOTIC RESISTANCE
4c75:C (GLY42) to (ASN214) CONSENSUS (ALL-CON) BETA-LACTAMASE CLASS A | HYDROLASE, ANTIBIOTIC RESISTANCE
4c75:D (GLY42) to (ASN214) CONSENSUS (ALL-CON) BETA-LACTAMASE CLASS A | HYDROLASE, ANTIBIOTIC RESISTANCE
3opp:A (ARG43) to (ASP213) ESBL R164S MUTANT OF SHV-1 BETA-LACTAMASE COMPLEXED WITH SA2-13 | CLASS A BETA-LACTAMASE, HYDROLASE
4uhu:A (GLY42) to (ASN214) W229D MUTANT OF THE LAST COMMON ANCESTOR OF GRAM-NEGATIVE BACTERIA (GNCA) BETA-LACTAMASE CLASS A | HYDROLASE, PRECAMBRIAN, RESURRECTED BETA-LACTAMASE, GNCA
4dxb:A (ALA398) to (GLY574) 2.29A STRUCTURE OF THE ENGINEERED MBP TEM-1 FUSION PROTEIN RG13 IN COMPLEX WITH ZINC, P1 SPACE GROUP | TEM, BETA-LACTAMASE, MBP, ALLOSTERIC REGULATION, ZINC BINDING, MALTOSE BINDING, SUGAR BINDING PROTEIN, HYDROLASE
4dxb:B (LEU413) to (GLY574) 2.29A STRUCTURE OF THE ENGINEERED MBP TEM-1 FUSION PROTEIN RG13 IN COMPLEX WITH ZINC, P1 SPACE GROUP | TEM, BETA-LACTAMASE, MBP, ALLOSTERIC REGULATION, ZINC BINDING, MALTOSE BINDING, SUGAR BINDING PROTEIN, HYDROLASE
4fd8:A (ARG43) to (ASP214) STRUCTURE OF APO S70C SHV BETA-LACTAMASE | CLASS A BETA-LACTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, HYDROLASE
4fh4:A (ARG43) to (ASP213) HIGH-RESOLUTION STRUCTURE OF APO WT SHV-1 BETA-LACTAMASE | CLASS A BETA-LACTAMASE, HYDROLASE
4gku:A (LEU55) to (ASP212) CRYSTAL STRUCTURE OF BETA LACTAMASE IN PET-15B | BETA LACTAMASE, HYDROLASE
4gog:A (GLN38) to (ASN209) CRYSTAL STRUCTURE OF THE GES-1 IMIPENEM ACYL-ENZYME COMPLEX | BETA-LACTAMASE, CARBAPENEMASE, IMIPENEM, HYDROLASE-ANTIBIOTIC COMPLEX
4gog:B (GLN38) to (ASN209) CRYSTAL STRUCTURE OF THE GES-1 IMIPENEM ACYL-ENZYME COMPLEX | BETA-LACTAMASE, CARBAPENEMASE, IMIPENEM, HYDROLASE-ANTIBIOTIC COMPLEX