4ibn:A (THR14) to (GLN169) CRYSTAL STRUCTURE OF LC9-RNASE H1, A TYPE 1 RNASE H WITH THE TYPE 2 ACTIVE-SITE MOTIF | RNASE H, RIBONUCLEASE H, HYDROLASE', HYDROLASE
2qk9:A (ASP138) to (LYS282) HUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 18-MER RNA/DNA HYBRID | RNASE H; RNA/DNA HYBRID, HYDROLASE-DNA-RNA COMPLEX
2qkb:A (VAL141) to (LYS282) HUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 20-MER RNA/DNA HYBRID | RNASE H; RNA/DNA HYBRID, HYDROLASE/DNA/RNA COMPLEX
2qkb:B (VAL140) to (ALA281) HUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 20-MER RNA/DNA HYBRID | RNASE H; RNA/DNA HYBRID, HYDROLASE/DNA/RNA COMPLEX
3h08:A (ILE5) to (ASN145) CRYSTAL STRUCTURE OF THE RIBONUCLEASE H1 FROM CHLOROBIUM TEPIDUM | RNASE H, 3D-STRUCTURE, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, NUCLEASE
3h08:B (GLU2) to (ASN145) CRYSTAL STRUCTURE OF THE RIBONUCLEASE H1 FROM CHLOROBIUM TEPIDUM | RNASE H, 3D-STRUCTURE, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, NUCLEASE
2rn2:A (VAL5) to (ASN143) STRUCTURAL DETAILS OF RIBONUCLEASE H FROM ESCHERICHIA COLI AS REFINED TO AN ATOMIC RESOLUTION | HYDROLASE(ENDORIBONUCLEASE)
2e4l:A (LYS5) to (ALA145) THERMODYNAMIC AND STRUCTURAL ANALYSIS OF THERMOLABILE RNASE HI FROM SHEWANELLA ONEIDENSIS MR-1 | HYDROLASE, ENDORIBONUCLEASE, RNASE HI, SHEWANELLA ONEIDENSIS MR-1
1f21:A (LYS3) to (ASN143) DIVALENT METAL COFACTOR BINDING IN THE KINETIC FOLDING TRAJECTORY OF E. COLI RIBONUCLEASE HI | RNASE H, NUCLEASE, RNASE H*, RIBNUCLEASE H, METAL-BINDING PROTEIN, PROTEIN FOLDING, HYDROLASE
3u3g:D (ASN2) to (ALA125) STRUCTURE OF LC11-RNASE H1 ISOLATED FROM COMPOST BY METAGENOMIC APPROACH: INSIGHT INTO THE STRUCTURAL BASES FOR UNUSUAL ENZYMATIC PROPERTIES OF STO-RNASE H1 | HYDROLASE, CLEAVE THE RNA STRAND OF RNA/DNA HYBRID
1rbr:A (VAL5) to (ASN143) STRUCTURAL STUDY OF MUTANTS OF ESCHERICHIA COLI RIBONUCLEASE HI WITH ENHANCED THERMOSTABILITY | HYDROLASE(ENDORIBONUCLEASE)
1rbt:A (VAL5) to (ASN143) STRUCTURAL STUDY OF MUTANTS OF ESCHERICHIA COLI RIBONUCLEASE HI WITH ENHANCED THERMOSTABILITY | HYDROLASE(ENDORIBONUCLEASE)
1rbu:A (VAL5) to (ASN143) STRUCTURAL STUDY OF MUTANTS OF ESCHERICHIA COLI RIBONUCLEASE HI WITH ENHANCED THERMOSTABILITY | HYDROLASE(ENDORIBONUCLEASE)
1rbv:A (VAL5) to (ASN143) STRUCTURAL STUDY OF MUTANTS OF ESCHERICHIA COLI RIBONUCLEASE HI WITH ENHANCED THERMOSTABILITY | HYDROLASE(ENDORIBONUCLEASE)
1rda:A (VAL5) to (ASN143) CRYSTAL STRUCTURES OF RIBONUCLEASE HI ACTIVE SITE MUTANTS FROM ESCHERICHIA COLI | HYDROLASE(ENDORIBONUCLEASE)
1rdc:A (GLU6) to (ASN143) CRYSTAL STRUCTURES OF RIBONUCLEASE HI ACTIVE SITE MUTANTS FROM ESCHERICHIA COLI | HYDROLASE(ENDORIBONUCLEASE)
1rdd:A (GLN4) to (ASN143) CRYSTAL STRUCTURE OF ESCHERICHIA COLI RNASE HI IN COMPLEX WITH MG2+ AT 2.8 ANGSTROMS RESOLUTION: PROOF FOR A SINGLE MG2+ SITE | HYDROLASE(ENDORIBONUCLEASE)
1ril:A (VAL5) to (SER143) CRYSTAL STRUCTURE OF RIBONUCLEASE H FROM THERMUS THERMOPHILUS HB8 REFINED AT 2.8 ANGSTROMS RESOLUTION | HYDROLASE(ENDORIBONUCLEASE)
1rnh:A (LYS3) to (PRO144) STRUCTURE OF RIBONUCLEASE H PHASED AT 2 ANGSTROMS RESOLUTION BY MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN | HYDROLASE(ENDORIBONUCLEASE)
4z0u:A (LYS3) to (ASN143) RNASE HI/SSB-CT COMPLEX | RIBONUCLEASE, PEPTIDE COMPLEX, HYDROLASE-PEPTIDE COMPLEX
4z0u:B (LYS3) to (ASN143) RNASE HI/SSB-CT COMPLEX | RIBONUCLEASE, PEPTIDE COMPLEX, HYDROLASE-PEPTIDE COMPLEX
1g15:A (LYS3) to (ASN143) CO-CRYSTAL OF E. COLI RNASE HI WITH TWO MN2+ IONS BOUND IN THE THE ACTIVE SITE | RIBONUCLEASE H, RNASE H, NUCLEASE, DIVALENT METAL BINDING, ACTIVATION/ATTENUATION MECHANISM, HYDROLASE
3v1r:A (THR520) to (LEU665) CRYSTAL STRUCTURES OF THE REVERSE TRANSCRIPTASE-ASSOCIATED RIBONUCLEASE H DOMAIN OF XMRV WITH INHIBITOR BETA-THUJAPLICINOL | REVERSE TRANSCRIPTION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1goa:A (GLU6) to (ASN143) COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION | HYDROLASE(ENDORIBONUCLEASE)
1gob:A (VAL5) to (ASN143) COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION | HYDROLASE(ENDORIBONUCLEASE)
1goc:A (VAL5) to (ASN143) COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION | HYDROLASE(ENDORIBONUCLEASE)
4ly7:A (LEU2) to (SER143) ANCESTRAL RNASE H | RIBONUCLEASE, HYDROLASE
1jl1:A (LYS3) to (ASN143) D10A E. COLI RIBONUCLEASE HI | RNASE HI, PROTEIN STABILITY, THERMOSTABILITY, HYDROGEN EXCHANGE, COOPERATIVITY, HYDROLASE
1jl2:A (LYS3) to (ASN144) CRYSTAL STRUCTURE OF TCEO RNASE H-A CHIMERA COMBINING THE FOLDING CORE FROM T. THERMOPHILUS RNASE H AND THE REMAINING REGION OF E. COLI RNASE H | MIXED ALPHA-BETA PROTEIN, HYDROLASE
1jxb:A (LYS3) to (ASN143) I53A, A POINT MUTANT OF THE CYSTEINE-FREE VARIANT OF E. COLI RNASE HI | MIXED ALPHA/BETA, 4-HELIX BUNDLE, HYDROLASE
1wse:A (VAL5) to (ASN143) CO-CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (E48A*) WITH MN2+ | RNASE H, ACTIVE-SITE MUTANT, CO-CRYSTAL STRUCTURE WITH MN2+, X-RAY CRYSTALLOGRAPHY, METAL FLUCTUATION MODEL, HYDROLASE
1wse:B (VAL5) to (ASN143) CO-CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (E48A*) WITH MN2+ | RNASE H, ACTIVE-SITE MUTANT, CO-CRYSTAL STRUCTURE WITH MN2+, X-RAY CRYSTALLOGRAPHY, METAL FLUCTUATION MODEL, HYDROLASE
1wsf:A (VAL5) to (ASN143) CO-CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (D134A*) WITH MN2+ | RNASE H, ACTIVE-SITE MUTANT, CO-CRYSTAL STRUCTURE WITH MN2+, X-RAY CRYSTALLOGRAPHY, METAL FLUCTUATION MODEL, HYDROLASE
1wsf:B (GLU6) to (ASN143) CO-CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (D134A*) WITH MN2+ | RNASE H, ACTIVE-SITE MUTANT, CO-CRYSTAL STRUCTURE WITH MN2+, X-RAY CRYSTALLOGRAPHY, METAL FLUCTUATION MODEL, HYDROLASE
1wsf:C (VAL5) to (ASN143) CO-CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (D134A*) WITH MN2+ | RNASE H, ACTIVE-SITE MUTANT, CO-CRYSTAL STRUCTURE WITH MN2+, X-RAY CRYSTALLOGRAPHY, METAL FLUCTUATION MODEL, HYDROLASE
1wsf:D (VAL5) to (MET142) CO-CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (D134A*) WITH MN2+ | RNASE H, ACTIVE-SITE MUTANT, CO-CRYSTAL STRUCTURE WITH MN2+, X-RAY CRYSTALLOGRAPHY, METAL FLUCTUATION MODEL, HYDROLASE
1wsg:A (MET1) to (ASN143) CO-CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (E48A/D134N*) WITH MN2+ | RNASE H, ACTIVE-SITE MUTANT, CO-CRYSTAL STRUCTURE WITH MN2+, X-RAY CRYSTALLOGRAPHY, METAL FLUCTUATION MODEL, HYDROLASE
1wsg:B (VAL5) to (ASN143) CO-CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (E48A/D134N*) WITH MN2+ | RNASE H, ACTIVE-SITE MUTANT, CO-CRYSTAL STRUCTURE WITH MN2+, X-RAY CRYSTALLOGRAPHY, METAL FLUCTUATION MODEL, HYDROLASE
1wsg:C (VAL5) to (ASN143) CO-CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (E48A/D134N*) WITH MN2+ | RNASE H, ACTIVE-SITE MUTANT, CO-CRYSTAL STRUCTURE WITH MN2+, X-RAY CRYSTALLOGRAPHY, METAL FLUCTUATION MODEL, HYDROLASE
1wsg:D (MET1) to (ASN143) CO-CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (E48A/D134N*) WITH MN2+ | RNASE H, ACTIVE-SITE MUTANT, CO-CRYSTAL STRUCTURE WITH MN2+, X-RAY CRYSTALLOGRAPHY, METAL FLUCTUATION MODEL, HYDROLASE
1wsh:B (VAL5) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (E48A/K87A) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsh:C (LEU2) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (E48A/K87A) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsh:D (VAL5) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (E48A/K87A) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsi:A (VAL5) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (E48A/K87A/D134N) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsi:B (LEU2) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (E48A/K87A/D134N) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsi:C (VAL5) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (E48A/K87A/D134N) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsi:D (VAL5) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (E48A/K87A/D134N) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsj:A (MET1) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (K87A/H124A) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsj:B (MET1) to (MET142) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (K87A/H124A) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsj:C (MET1) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (K87A/H124A) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsj:D (MET1) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (K87A/H124A) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsj:E (VAL5) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (K87A/H124A) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsj:F (LEU2) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (K87A/H124A) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsj:G (MET1) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (K87A/H124A) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1wsj:H (MET1) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI ACTIVE SITE MUTANT (K87A/H124A) | RNASE H, ACTIVE-SITE MUTANT, X-RAY CRYSTALLOGRAPHY, HYDROLASE
1kva:A (VAL5) to (ASN143) E. COLI RIBONUCLEASE HI D134A MUTANT | HYDROLASE, ENDORIBONUCLEASE, MUTANT
1kvb:A (LYS3) to (MET142) E. COLI RIBONUCLEASE HI D134H MUTANT | HYDROLASE, ENDORIBONUCLEASE, MUTANT
1kvc:A (ASP10) to (ASN143) E. COLI RIBONUCLEASE HI D134N MUTANT | HYDROLASE, ENDORIBONUCLEASE, MUTANT
3jyt:A (GLU438) to (VAL552) K65R MUTANT HIV-1 REVERSE TRANSCRIPTASE CROSS-LINKED TO DS- DNA AND COMPLEXED WITH DATP AS THE INCOMING NUCLEOTIDE SUBSTRATE | HIV-1 REVERSE TRANSCRIPTASE, TENOFOVIR, RT-DNA COMPLEX, TRANSFERASE/DNA COMPLEX, DRUG RESISTANCE MUTATION, AIDS, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, RNASE H, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDYLTRANSFERASE, RNA- DIRECTED DNA POLYMERASE TRANSFERASE
1law:A (VAL5) to (ASN143) STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY CAVITY- FILLING MUTATIONS WITHIN A HYDROPHOBIC CORE | HYDROLASE
2yv0:X (GLU6) to (ASN143) STRUCTURAL AND THERMODYNAMIC ANALYSES OF E. COLI RIBONUCLEASE HI VARIANT WITH QUINTUPLE THERMOSTABILIZING MUTATIONS | RNASE HI, QUINTUPLE THERMOSTABILIZING MUTATIONS, E. COLI, HYDROLASE
2z1g:A (LYS3) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI SURFACE CHARGED MUTANT(Q4R/T40E/Q72H/Q76K/Q80E/T92K/Q105K) | RNASE HI, THERMOSTABILITY, SURFACE-CHARGE RESIDUE, HYDROLASE
2z1h:A (VAL5) to (MET142) CRYSTAL STRUCTURE OF E.COLI RNASE HI SURFACE CHARGED MUTANT(Q4R/T92K/Q105K/Q113R/Q115K/N143K/T145K) | RNASE HI, THERMOSTABILITY, SURFACE-CHARGE RESIDUE, HYDROLASE
2z1i:A (VAL5) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI SURFACE CHARGED MUTANT(Q4R/T40E/Q72H/Q76K/Q80E/T92K/Q105K/Q113R/Q115K) | RNASE HI, THERMOSTABILITY, SURFACE-CHARGE RESIDUE, HYDROLASE
2z1i:B (LYS3) to (ASN143) CRYSTAL STRUCTURE OF E.COLI RNASE HI SURFACE CHARGED MUTANT(Q4R/T40E/Q72H/Q76K/Q80E/T92K/Q105K/Q113R/Q115K) | RNASE HI, THERMOSTABILITY, SURFACE-CHARGE RESIDUE, HYDROLASE
2z1j:A (LEU2) to (MET142) CRYSTAL STRUCTURE OF E.COLI RNASE HI SURFACE CHARGED MUTANT(Q4R/T40E/Q72H/Q76K/Q80E/T92K/Q105K/Q113R/Q115K/N143K /T145K) | RNASE HI, THERMOSTABILITY, SURFACE-CHARGE RESIDUE, HYDROLASE
2zqb:C (HIS8) to (ALA145) CRYSTAL STRUCTURE OF A PSYCHROTROPHIC RNASEHI VARIANT WITH SEXTUPLE THERMOSTABILIZING MUTATIONS | HYDROLASE, CYTOPLASM, ENDONUCLEASE, MAGNESIUM, METAL- BINDING, NUCLEASE
2zqb:D (GLU3) to (ALA145) CRYSTAL STRUCTURE OF A PSYCHROTROPHIC RNASEHI VARIANT WITH SEXTUPLE THERMOSTABILIZING MUTATIONS | HYDROLASE, CYTOPLASM, ENDONUCLEASE, MAGNESIUM, METAL- BINDING, NUCLEASE
3aa2:A (VAL5) to (ASN143) A52I E. COLI RNASE HI | STABILITY, CAVITY, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, NUCLEASE
3aa3:A (VAL5) to (ASN143) A52L E. COLI RNASE HI | STABILITY, CAVITY, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, NUCLEASE
3aa4:A (LEU2) to (MET142) A52V E.COLI RNASE HI | STABILITY, CAVITY, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, NUCLEASE
3aa5:X (VAL5) to (ASN143) A52F E.COLI RNASE HI | STABILITY, CAVITY, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, NUCLEASE
1rdb:A (VAL5) to (ASN143) CRYSTAL STRUCTURES OF RIBONUCLEASE HI ACTIVE SITE MUTANTS FROM ESCHERICHIA COLI | HYDROLASE(ENDORIBONUCLEASE)
3v1o:A (THR520) to (THR667) CRYSTAL STRUCTURES OF THE REVERSE TRANSCRIPTASE-ASSOCIATED RIBONUCLEASE H DOMAIN OF XENOTROPIC MURINE LEUKEMIA-VIRUS RELATED VIRUS | REVERSE TRANSCRIPTION, HYDROLASE
1lav:A (VAL5) to (ASN143) STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY CAVITY- FILLING MUTATIONS WITHIN A HYDROPHOBIC CORE | HYDROLASE