1nav:A (CYS244) to (GLU391) THYROID RECEPTOR ALPHA IN COMPLEX WITH AN AGONIST SELECTIVE FOR THYROID RECEPTOR BETA1 | NUCLEAR RECEPTOR, THYROID RECEPTOR, LIGAND, COMPLEX, MEMBRANE PROTEIN
1nax:A (PRO297) to (GLU445) THYROID RECEPTOR BETA1 IN COMPLEX WITH A BETA-SELECTIVE LIGAND | NUCLEAR RECEPTOR, THYROID RECEPTOR, COMPLEX, MEMBRANE PROTEIN
4whf:B (SER100) to (ASP249) CRYSTAL STRUCTURE OF TR3 LBD IN COMPLEX WITH 1-(3,4,5- TRIHYDROXYPHENYL)DECAN-1-ONE | LBD, TRANSCRIPTION
2ayr:A (THR371) to (MET528) A SERM DESIGNED FOR THE TREATMENT OF UTERINE LEIOMYOMA WITH UNIQUE TISSUE SPECIFICITY FOR UTERUS AND OVARIES IN RATS | RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, LIGAND- BINDING, SERM
1nrl:B (PRO268) to (PRO419) CRYSTAL STRUCTURE OF THE HUMAN PXR-LBD IN COMPLEX WITH AN SRC-1 COACTIVATOR PEPTIDE AND SR12813 | NUCLEAR RECEPTOR, COACTIVATOR, PXR, XENOBIOTIC, SRC-1, LIGAND BINDING DOMAIN, TRANSCRIPTION
2p7a:A (SER293) to (THR420) CRYSTAL STRUCTURE OF ESTROGEN RELATED RECEPTOR G IN COMPLEX WITH 3-METHYL PHENOL | THREE LAYERED ALPHA HELICAL SANDWICH, HORMONE RECEPTOR
3eyb:A (PRO322) to (HIS464) STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THE LIGAND BINDING DOMAIN OF A NON-DUPLICATED RXR FROM THE INVERTEBRATE CHORDATE AMPHIOXUS | AMPHIOXUS, RETINOID X RECEPTOR, NUCLEAR RECEPTOR, LIGAND BINDING, DNA-BINDING, METAL-BINDING, NUCLEUS, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC-FINGER, STRUCTURAL GENOMICS, STRUCTURAL PROTEOMICS IN EUROPE, SPINE
3eyb:C (PRO322) to (HIS464) STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THE LIGAND BINDING DOMAIN OF A NON-DUPLICATED RXR FROM THE INVERTEBRATE CHORDATE AMPHIOXUS | AMPHIOXUS, RETINOID X RECEPTOR, NUCLEAR RECEPTOR, LIGAND BINDING, DNA-BINDING, METAL-BINDING, NUCLEUS, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC-FINGER, STRUCTURAL GENOMICS, STRUCTURAL PROTEOMICS IN EUROPE, SPINE
3eyb:D (PRO322) to (HIS464) STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THE LIGAND BINDING DOMAIN OF A NON-DUPLICATED RXR FROM THE INVERTEBRATE CHORDATE AMPHIOXUS | AMPHIOXUS, RETINOID X RECEPTOR, NUCLEAR RECEPTOR, LIGAND BINDING, DNA-BINDING, METAL-BINDING, NUCLEUS, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC-FINGER, STRUCTURAL GENOMICS, STRUCTURAL PROTEOMICS IN EUROPE, SPINE
4x1f:A (PRO268) to (ASP416) CRYSTAL STRUCTURE OF THE HPXR-LBD IN COMPLEX WITH THE SYNTHETIC ESTROGEN 17ALPHA-ETHINYLESTRADIOL | NUCLEAR RECEPTOR, HORMONE RECEPTOR, PREGNANE X RECEPTOR, ESTROGEN, GENE REGULATION
3f5c:A (VAL390) to (GLY543) STRUCTURE OF DAX-1:LRH-1 COMPLEX | NUCLEAR RECEPTOR, TRANSCRIPTIONAL COREPRESSOR, REGULATORY COMPLEX, DNA-BINDING, LIPID-BINDING, METAL-BINDING, NUCLEUS, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC, ZINC-FINGER, CYTOPLASM, REPRESSOR
3fal:B (SER280) to (ASP430) HUMANRXR ALPHA & MOUSE LXR ALPHA COMPLEXED WITH RETENOIC ACID AND GSK2186 | NUCLEAR HORMONE RECEPTOR NONSTEROIDAL LXR AGONIST CHOLOESTOROL METABOLISM, DNA-BINDING, HOST-VIRUS INTERACTION, METAL-BINDING, NUCLEUS, POLYMORPHISM, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, UBL CONJUGATION, ZINC, ZINC-FINGER, SIGNALING PROTEIN
2pjl:A (SER349) to (LYS499) CRYSTAL STRUCTURE OF HUMAN ESTROGEN-RELATED RECEPTOR ALPHA IN COMPLEX WITH A SYNTHETIC INVERSE AGONIST REVEALS ITS NOVEL MOLECULAR MECHANISM | NUCLEAR HORMONE RECEPTOR, LIGAND BINDING DOMAIN, LIGAND BINDING POCKET, THREE-LAYERED ALPHA-HELICAL SANDWICH, INVERSE AGONIST, HELIX 12 (H12), COACTIVATOR GROOVE, TRANSCRIPTION
2pjl:B (SER349) to (LEU479) CRYSTAL STRUCTURE OF HUMAN ESTROGEN-RELATED RECEPTOR ALPHA IN COMPLEX WITH A SYNTHETIC INVERSE AGONIST REVEALS ITS NOVEL MOLECULAR MECHANISM | NUCLEAR HORMONE RECEPTOR, LIGAND BINDING DOMAIN, LIGAND BINDING POCKET, THREE-LAYERED ALPHA-HELICAL SANDWICH, INVERSE AGONIST, HELIX 12 (H12), COACTIVATOR GROOVE, TRANSCRIPTION
4xi3:C (THR371) to (MET528) ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH BAZEDOXIFENE | ESTROGEN RECEPTOR, SERM, BAZEDOXIFENE, BREAST CANCER, NUCLEAR HORMONE RECEPTOR, SIGNALING PROTEIN
4xi3:D (THR371) to (SER527) ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH BAZEDOXIFENE | ESTROGEN RECEPTOR, SERM, BAZEDOXIFENE, BREAST CANCER, NUCLEAR HORMONE RECEPTOR, SIGNALING PROTEIN
3fs1:A (PRO203) to (LEU331) CRYSTAL STRUCTURE OF HNF4A LBD IN COMPLEX WITH THE LIGAND AND THE COACTIVATOR PGC-1A FRAGMENT | NUCLEAR RECEPTOR, COACTIVATOR, LXXLL MOTIF, MODY, DIABETES, ALTERNATIVE PROMOTER USAGE, ALTERNATIVE SPLICING, DIABETES MELLITUS, DISEASE MUTATION, DNA-BINDING, METAL-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC, ZINC-FINGER
2q60:A (PRO168) to (GLU309) CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF POLYANDROCARPA MISAKIENSIS RXR IN TETRAMER IN ABSENCE OF LIGAND | NUCLEAR RECEPTOR. RXR LIGAND BINDING DOMAIN, APO-TETRAMER, TRANSCRIPTION
2q60:B (PRO168) to (HIS310) CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF POLYANDROCARPA MISAKIENSIS RXR IN TETRAMER IN ABSENCE OF LIGAND | NUCLEAR RECEPTOR. RXR LIGAND BINDING DOMAIN, APO-TETRAMER, TRANSCRIPTION
2q60:C (PRO168) to (HIS310) CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF POLYANDROCARPA MISAKIENSIS RXR IN TETRAMER IN ABSENCE OF LIGAND | NUCLEAR RECEPTOR. RXR LIGAND BINDING DOMAIN, APO-TETRAMER, TRANSCRIPTION
2q60:D (PRO168) to (LEU308) CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF POLYANDROCARPA MISAKIENSIS RXR IN TETRAMER IN ABSENCE OF LIGAND | NUCLEAR RECEPTOR. RXR LIGAND BINDING DOMAIN, APO-TETRAMER, TRANSCRIPTION
2q6j:A (THR371) to (ASN532) CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR ALPHA COMPLEXED TO A B-N SUBSTITUTED LIGAND | PROTEIN-LIGAND COMPLEX, TRANSCRIPTION
2qa6:B (THR371) to (ASN532) CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR ALPHA MUTANT 537S COMPLEXED WITH 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL | PROTEIN-LIGAND COMPLEX, TRANSCRIPTION
2qa8:B (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN MUTANT 537S COMPLEXED WITH GENISTEIN | PROTEIN-LIGAND COMPLEX, TRANSCRIPTION
2qe4:B (THR371) to (MET528) ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A BENZOPYRAN AGONIST | NUCLEAR RECEPTOR, LIGAND-BINDING DOMAIN, ALTERNATIVE SPLICING, DNA-BINDING, LIPID-BINDING, METAL-BINDING, NUCLEAR PROTEIN, PHOSPHORYLATION, POLYMORPHISM, STEROID- BINDING, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC, ZINC-FINGER
1pcg:A (THR371) to (ASN532) HELIX-STABILIZED CYCLIC PEPTIDES AS SELECTIVE INHIBITORS OF STEROID RECEPTOR-COACTIVATOR INTERACTIONS | CO-ACTIVATOR BINDING SITE, TRANSCRIPTION-INHIBITOR COMPLEX
1pcg:B (THR371) to (ASN532) HELIX-STABILIZED CYCLIC PEPTIDES AS SELECTIVE INHIBITORS OF STEROID RECEPTOR-COACTIVATOR INTERACTIONS | CO-ACTIVATOR BINDING SITE, TRANSCRIPTION-INHIBITOR COMPLEX
2qh6:A (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN COMPLEXED WITH AN OXABICYCLIC DIARYLETHYLENE COMPOUND | PROTEIN-LIGAND COMPLEX, TRANSCRIPTION
4iv4:A (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH CONSTRAINED WAY-DERIVATIVE, 5B | NUCLEAR HORMONE RECEPTOR, TRANSCRIPTION FACTOR, LIGAND-BINDING, NUCLEUS, TRANSCRIPTION
4iwf:A (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A DYNAMIC OXIME-DERIVATIVE | NUCLEAR HORMONE RECEPTOR, TRANSCRIPTION FACTOR, LIGAND-BINDING, NUCLEUS, TRANSCRIPTION
1pq6:C (GLY296) to (GLN438) HUMAN LXR BETA HORMONE RECEPTOR / GW3965 COMPLEX | LXRB+KB043546/WAY207380/GW3965, TRANSCRIPTION REGULATION
1pq9:A (GLY296) to (ARG411) HUMAN LXR BETA HORMONE RECEPTOR COMPLEXED WITH T0901317 COMPLEX | LXRB+T0901317 SPLIT, TRANSCRIPTION REGULATION
2qw4:A (SER100) to (ASP249) HUMAN NR4A1 LIGAND-BINDING DOMAIN | NUCLEAR RECEPTOR, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, DNA-BINDING, METAL-BINDING, NUCLEUS, PHOSPHORYLATION, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC- FINGER, HORMONE RECEPTOR
2qw4:C (SER100) to (ASP249) HUMAN NR4A1 LIGAND-BINDING DOMAIN | NUCLEAR RECEPTOR, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, DNA-BINDING, METAL-BINDING, NUCLEUS, PHOSPHORYLATION, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC- FINGER, HORMONE RECEPTOR
2r6y:A (THR371) to (MET528) ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A SERM | ESTROGEN RECEPTOR, LIGAND-BINDING DOMAIN, ALTERNATIVE SPLICING, DNA-BINDING, LIPID-BINDING, METAL-BINDING, NUCLEUS, PHOSPHORYLATION, POLYMORPHISM, STEROID-BINDING, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC, ZINC-FINGER
4jgv:B (SER431) to (GLU579) CRYSTAL STRUCTURE OF HUMAN NUR77 LIGAND-BINDING DOMAIN IN COMPLEX WITH THPN | TRANSCRIPTION
1ere:A (THR371) to (ASN532) HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH 17BETA-ESTRADIOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, STEROID, AGONIST
1ere:B (THR371) to (ASN532) HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH 17BETA-ESTRADIOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, STEROID, AGONIST
1ere:E (THR371) to (ASN532) HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH 17BETA-ESTRADIOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, STEROID, AGONIST
1qku:A (THR371) to (ASN532) WILD TYPE ESTROGEN NUCLEAR RECEPTOR LIGAND BINDING DOMAIN COMPLEXED WITH ESTRADIOL | NUCLEAR RECEPTOR, AGONISM, ANTAGONISM, CRYSTAL STRUCTURE, ESTRADIOL RECEPTOR, STEROID, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, STRUCTURAL GENOMICS
1qku:B (THR371) to (ASN532) WILD TYPE ESTROGEN NUCLEAR RECEPTOR LIGAND BINDING DOMAIN COMPLEXED WITH ESTRADIOL | NUCLEAR RECEPTOR, AGONISM, ANTAGONISM, CRYSTAL STRUCTURE, ESTRADIOL RECEPTOR, STEROID, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, STRUCTURAL GENOMICS
1qku:C (THR371) to (ASN532) WILD TYPE ESTROGEN NUCLEAR RECEPTOR LIGAND BINDING DOMAIN COMPLEXED WITH ESTRADIOL | NUCLEAR RECEPTOR, AGONISM, ANTAGONISM, CRYSTAL STRUCTURE, ESTRADIOL RECEPTOR, STEROID, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, STRUCTURAL GENOMICS
3hlv:B (THR371) to (ASN532) CRYSTAL STRUCTURE OF HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1 NR BOX II PEPTIDE AND 16-ALPHA-HYDROXY-ESTRONE ((8S,9R,13S,14R, 16R)-3,16-DIHYDROXY-13-METHYL-7,8,9,11,12,14,15, 16-OCTAHYDRO-6H- CYCLOPENTA[A]PHENANTHREN-17-ONE | ESTROGEN RECEPTOR, LBD, GRIP PEPTIDE, HYDROXY-ESTRONE, ALTERNATIVE SPLICING, DNA-BINDING, GLYCOPROTEIN, LIPID-BINDING, METAL-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, RECEPTOR, STEROID-BINDING, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC, ZINC-FINGER, ACTIVATOR, HORMONE, NUCLEAR RECEPTOR
2v7c:B (ILE423) to (MSE567) CRYSTAL STRUCTURE OF REV-ERB BETA | DNA-BINDING, TRANSCRIPTION, METAL-BINDING, ZINC, NUCLEUS, RECEPTOR, REPRESSOR, ZINC-FINGER, CONSTITUTIVE REPRESSION, TRANSCRIPTION REGULATION, ORPHAN RECEPTOR, A-HELICAL SANDWICH
1rkh:A (THR251) to (GLN403) CRYSTAL STRUCTURE OF THE RAT VITAMIN D RECEPTOR LIGAND BINDING DOMAIN COMPLEXED WITH 2AM20R AND A SYNTHETIC PEPTIDE CONTAINING THE NR2 BOX OF DRIP 205 | NUCLEAR RECEPTOR-LIGAND COMPLEX, NUCLEAR RECEPTOR- COACTIVATOR INTERACTIONS, HORMONE/GROWTH FACTOR RECEPTOR COMPLEX
1g1u:A (PRO293) to (GLU434) THE 2.5 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE RXRALPHA LIGAND BINDING DOMAIN IN TETRAMER IN THE ABSENCE OF LIGAND | CRYSTAL STRUCTURE, RXRALPHA LIGAND BINDING DOMAIN, TETRAMER, ABSENCE OF LIGAND, TRANSCRIPTION
1g50:B (THR1371) to (ASN1532) CRYSTAL STRUCTURE OF A WILD TYPE HER ALPHA LBD AT 2.9 ANGSTROM RESOLUTION | ALPHA HELICES, ESTRADIOL, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, STRUCTURAL GENOMICS, DNA BINDING PROTEIN
1g50:C (THR2371) to (ASN2532) CRYSTAL STRUCTURE OF A WILD TYPE HER ALPHA LBD AT 2.9 ANGSTROM RESOLUTION | ALPHA HELICES, ESTRADIOL, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, STRUCTURAL GENOMICS, DNA BINDING PROTEIN
1g5y:A (PRO293) to (GLU434) THE 2.0 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE RXRALPHA LIGAND BINDING DOMAIN TETRAMER IN THE PRESENCE OF A NON-ACTIVATING RETINOIC ACID ISOMER. | RXRALPHA LIGAND BINDING DOMAIN, INACTIVE TETRAMER WITH 2 MONOMERS BOUND WITH AN INACTIVATING ISOMER OF RETINOIC ACID, TRANSCRIPTION
3uud:A (LEU372) to (ASN532) CRYSTAL STRUCTURE OF HERA-LBD (Y537S) IN COMPLEX WITH ESTRADIOL | LIGAND-BINDING DOMAIN OF NUCLEAR HORMONE RECEPTOR, HORMONE RECEPTOR
3uud:B (THR371) to (ASN532) CRYSTAL STRUCTURE OF HERA-LBD (Y537S) IN COMPLEX WITH ESTRADIOL | LIGAND-BINDING DOMAIN OF NUCLEAR HORMONE RECEPTOR, HORMONE RECEPTOR
3uvv:A (GLU243) to (CYS390) CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAINS OF THE THYROID RECEPTOR:RETINOID X RECEPTOR COMPLEXED WITH 3,3',5 TRIIODO-L- THYRONINE AND 9-CIS RETINOIC ACID | TR-RXR HETERODIMER, ALLOSTERY, ALPHA HELICAL SANDWICH, TRANSACTIVATION, HORMONE RECEPTOR-HORMONE RECEPTOR COMPLEX
3hvl:B (PRO268) to (PRO419) TETHERED PXR-LBD/SRC-1P COMPLEXED WITH SR-12813 | PXR, SRC-1, TETHERED, ENGINEERED, DRUG-DRUG INTERACTIONS, DNA- BINDING, METAL-BINDING, NUCLEUS, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC-FINGER, TRANSFERASE
1s9p:B (SER293) to (THR420) CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE ESTROGEN-RELATED RECEPTOR GAMMA IN COMPLEX WITH DIETHYLSTILBESTROL | LIGAND-BINDING DOMAIN, ANTAGONIST COMPLEX, TRANSCRIPTION
1s9p:C (SER293) to (MET419) CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE ESTROGEN-RELATED RECEPTOR GAMMA IN COMPLEX WITH DIETHYLSTILBESTROL | LIGAND-BINDING DOMAIN, ANTAGONIST COMPLEX, TRANSCRIPTION
3hzf:A (GLN247) to (GLU391) STRUCTURE OF TR-ALFA BOUND TO SELECTIVE THYROMIMETIC GC-1 IN C2 SPACE GROUP | NUCLEAR RECEPTOR, LIGAND BINDING DOMAIN, DNA-BINDING, METAL-BINDING, NUCLEUS, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC- FINGER
1gwr:A (THR371) to (ASN532) HUMAN OESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH 17BETA-OESTRADIOL AND TIF2 NRBOX3 PEPTIDE | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, TRANSACTIVATION, AGONIST, AF2 COACTIVATOR , RECEPTOR, ACTIVATOR, TRANSCRIPTI REGULATION, DNA-BINDING, NUCLEAR PROTEIN, ZINC FINGER, STER BINDING, PHOSPHORYLATION, POLYMORPHISM, ALTERNATIVE SPLICING
2gl8:A (THR72) to (LEU212) HUMAN RETINOIC ACID RECEPTOR RXR-GAMMA LIGAND-BINDING DOMAIN | NUCLEAR RECEPTOR, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, HORMONE-GROWTH FACTOR RECEPTOR COMPLEX
2gl8:B (THR72) to (HIS214) HUMAN RETINOIC ACID RECEPTOR RXR-GAMMA LIGAND-BINDING DOMAIN | NUCLEAR RECEPTOR, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, HORMONE-GROWTH FACTOR RECEPTOR COMPLEX
2gl8:D (THR72) to (HIS214) HUMAN RETINOIC ACID RECEPTOR RXR-GAMMA LIGAND-BINDING DOMAIN | NUCLEAR RECEPTOR, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, HORMONE-GROWTH FACTOR RECEPTOR COMPLEX
4znh:A (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH A 2-FLUORO-SUBSTITUTED OBHS DERIVATIVE | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
4znh:B (THR371) to (LYS529) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH A 2-FLUORO-SUBSTITUTED OBHS DERIVATIVE | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
4znw:B (THR371) to (SER527) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH A 4-BROMO-SUBSTITUTED OBHS DERIVATIVE | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
4zo1:X (PRO297) to (GLU445) CRYSTAL STRUCTURE OF THE T3-BOUND TR-BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH RXR-ALPHA | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, PROTEIN BINDING
4zo1:B (PRO293) to (HIS435) CRYSTAL STRUCTURE OF THE T3-BOUND TR-BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH RXR-ALPHA | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, PROTEIN BINDING
2gpv:B (SER293) to (MET419) ESTROGEN RELATED RECEPTOR-GAMMA LIGAND BINDING DOMAIN COMPLEXED WITH 4-HYDROXY-TAMOXIFEN AND A SMRT PEPTIDE | ESTROGEN RELATED RECEPTOR, ERR, ERRG, ESRRG, NUCLEAR RECEPTOR, STEROID RECEPTOR, SMRT, TAMOXIFEN, TRANSCRIPTION
2gpv:C (SER293) to (MET419) ESTROGEN RELATED RECEPTOR-GAMMA LIGAND BINDING DOMAIN COMPLEXED WITH 4-HYDROXY-TAMOXIFEN AND A SMRT PEPTIDE | ESTROGEN RELATED RECEPTOR, ERR, ERRG, ESRRG, NUCLEAR RECEPTOR, STEROID RECEPTOR, SMRT, TAMOXIFEN, TRANSCRIPTION
2gpv:D (SER293) to (MET419) ESTROGEN RELATED RECEPTOR-GAMMA LIGAND BINDING DOMAIN COMPLEXED WITH 4-HYDROXY-TAMOXIFEN AND A SMRT PEPTIDE | ESTROGEN RELATED RECEPTOR, ERR, ERRG, ESRRG, NUCLEAR RECEPTOR, STEROID RECEPTOR, SMRT, TAMOXIFEN, TRANSCRIPTION
2gpv:F (SER293) to (MET419) ESTROGEN RELATED RECEPTOR-GAMMA LIGAND BINDING DOMAIN COMPLEXED WITH 4-HYDROXY-TAMOXIFEN AND A SMRT PEPTIDE | ESTROGEN RELATED RECEPTOR, ERR, ERRG, ESRRG, NUCLEAR RECEPTOR, STEROID RECEPTOR, SMRT, TAMOXIFEN, TRANSCRIPTION
3ilz:A (ASP246) to (HIS387) STRUCTURE OF TR-ALFA BOUND TO SELECTIVE THYROMIMETIC GC-1 IN P212121 SPACE GROUP | NUCLEAR RECEPTOR, SIGNALING PROTEIN
1tfc:B (SER293) to (GLY442) CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE ESTROGEN-RELATED RECEPTOR GAMMA IN COMPLEX WITH A STEROID RECEPTOR COACTIVATOR-1 PEPTIDE | TRANSCRIPTIONALLY ACTIVE CONFORMATION IN ABSENCE OF LIGAND, TRANSCRIPTION
3ips:B (LEU275) to (ASP432) X-RAY STRUCTURE OF BENZISOXAZOLE SYNTHETIC AGONIST BOUND TO THE LXR- ALPHA | NUCLEAR RECEPTOR, LXR HOMODIMER, LXR SIGNALING, ALTERNATIVE SPLICING, NUCLEUS, POLYMORPHISM, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ACTIVATOR, ISOPEPTIDE BOND, PROTO-ONCOGENE, CHOLESTEROL, ABCA1, HETERODIMER, RXR, LIGAND COMPLEX
1hg4:D (LYS275) to (ARG480) ULTRASPIRACLE LIGAND BINDING DOMAIN FROM DROSOPHILA MELANOGASTER | NUCLEAR HORMONE RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING
1hg4:E (LYS275) to (PHE479) ULTRASPIRACLE LIGAND BINDING DOMAIN FROM DROSOPHILA MELANOGASTER | NUCLEAR HORMONE RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING
2h77:A (CYS244) to (ALA379) CRYSTAL STRUCTURE OF HUMAN TR ALPHA BOUND T3 IN MONOCLINIC SPACE GROUP | TR ALPHA, T3, HORMONE/GROWTH FACTOR COMPLEX
2h79:A (ASP246) to (HIS387) CRYSTAL STRUCTURE OF HUMAN TR ALPHA BOUND T3 IN ORTHORHOMBIC SPACE GROUP | TR ALPHA, TR, T3, HORMONE/GROWTH FACTOR COMPLEX
2has:A (THR255) to (SER405) CRYSTAL STRUCTURE OF VDR LBD IN COMPLEX WITH 2ALPHA-(1- PROPOXY) CALCITRIOL | ALPHA HELICAL SANDWICH, GENE REGULATION
4lnx:A (ASP246) to (GLU391) CRYSTAL STRUCTURE OF TR-ALPHA BOUND TO T4 IN A SECOND SITE | MAINLY ALPHA ORTHOGONAL BUNDLE, TRANSCRIPTION FACTOR, TRANSCRIPTION
2i0j:A (THR371) to (MET528) BENZOPYRANS ARE SELECTIVE ESTROGEN RECEPTOR BETA AGONISTS (SERBAS) WITH NOVEL ACTIVITY IN MODELS OF BENIGN PROSTATIC HYPERPLASIA | NUCLEAR RECEPTOR LIGAND BINDING DOMAIN, TRANSCRIPTION
2i0j:B (THR371) to (SER527) BENZOPYRANS ARE SELECTIVE ESTROGEN RECEPTOR BETA AGONISTS (SERBAS) WITH NOVEL ACTIVITY IN MODELS OF BENIGN PROSTATIC HYPERPLASIA | NUCLEAR RECEPTOR LIGAND BINDING DOMAIN, TRANSCRIPTION
2i0j:D (THR371) to (SER527) BENZOPYRANS ARE SELECTIVE ESTROGEN RECEPTOR BETA AGONISTS (SERBAS) WITH NOVEL ACTIVITY IN MODELS OF BENIGN PROSTATIC HYPERPLASIA | NUCLEAR RECEPTOR LIGAND BINDING DOMAIN, TRANSCRIPTION
4m8h:A (LEU294) to (ARG421) CRYSTAL STRUCTURE OF HUMAN RETINOID X RECEPTOR ALPHA-LIGAND BINDING DOMAIN COMPLEX WITH (R)4-METHYL 9CUAB30 AND COACTIVATOR PEPTIDE GRIP- 1 | ANTIPARALLEL SANDWICH, LIGAND BINDING, COACTIVATOR BINDING, DIMERIZATION, ACTIVATION FUNCTION, TRANSCRIPTION, NUCLEAR RECEPTORS, LIGAND BINDING DOMAIN, LIGAND BINDING POCKET, COACTIVATOR BINDING SITE, CANCER, (R)4-METHYL UAB30 [(2E,4E,6Z,8E)-8-[(4'R)METHYL-3',4'- DIHYDRO-1'(2'H)-NAPHTHALEN-1'-YLIDENE]-3,7-DIMETHYL-2,4,6- OCTATRIENOIC ACID]
5aau:A (THR371) to (SER527) OPTIMIZATION OF A NOVEL BINDING MOTIF TO TO (E)-3-(3,5- DIFLUORO-4-((1R,3R)-2-(2-FLUORO-2-METHYLPROPYL)-3-METHYL-2, 3,4,9-TETRAHYDRO-1H-PYRIDO(3,4-B)INDOL-1-YL)PHENYL)ACRYLIC ACID (AZD9496), A POTENT AND ORALLY BIOAVAILABLE SELECTIVE ESTROGEN RECEPTOR DOWNREGULATOR AND ANTAGONIST | SIGNALING PROTEIN, BREAST CANCER, ESTROGEN RECEPTOR DOWNREGULATOR, FULVESTRANT, AZD9496, NUCLEAR HORMONE RECEPTOR
5aau:B (THR371) to (SER527) OPTIMIZATION OF A NOVEL BINDING MOTIF TO TO (E)-3-(3,5- DIFLUORO-4-((1R,3R)-2-(2-FLUORO-2-METHYLPROPYL)-3-METHYL-2, 3,4,9-TETRAHYDRO-1H-PYRIDO(3,4-B)INDOL-1-YL)PHENYL)ACRYLIC ACID (AZD9496), A POTENT AND ORALLY BIOAVAILABLE SELECTIVE ESTROGEN RECEPTOR DOWNREGULATOR AND ANTAGONIST | SIGNALING PROTEIN, BREAST CANCER, ESTROGEN RECEPTOR DOWNREGULATOR, FULVESTRANT, AZD9496, NUCLEAR HORMONE RECEPTOR
4mg7:B (THR371) to (ASN532) CRYSTAL STRUCTURE OF HERA-LBD (Y537S) IN COMPLEX WITH FERUTININE | LIGAND-BINDING DOMAIN OF NUCLEAR HORMONE RECEPTOR, HORMONE RECEPTOR
4mg8:A (LEU372) to (ASN532) CRYSTAL STRUCTURE OF HERA-LBD (Y537S) IN COMPLEX WITH ALPHA-ZEARALANOL | LIGAND-BINDING DOMAIN OF NUCLEAR HORMONE RECEPTOR, HORMONE RECEPTOR
2iok:B (THR1371) to (SER1527) HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 1D | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, ER-ALPHA, ANTAGONIST
2j4a:A (CYS298) to (GLU445) HUMAN THYROID HORMONE RECEPTOR BETA LIGAND BINDING DOMAIN IN COMPLEX WITH KB131084 | NUCLEAR PROTEIN, DISEASE MUTATION, NUCLEAR RECEPTOR, ZINC, RECEPTOR, DEAFNESS, ZINC-FINGER, DNA-BINDING, TRANSCRIPTION REGULATION, TRANSCRIPTION, ALTERNATIVE SPLICING, LIGAND BINDING DOMAIN, POLYMORPHISM, METAL-BINDING
1vjb:B (SER293) to (LEU440) CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE ESTROGEN-RELATED RECEPTOR GAMMA IN COMPLEX WITH 4- HYDROXYTAMOXIFEN | LIGAND-BINDING DOMAIN, ANTAGONIST COMPLEX, TRANSCRIPTION
4n5g:A (PRO293) to (LEU436) CRYSTAL STRUCTURE OF RXRA LBD COMPLEXED WITH A SYNTHETIC MODULATOR K8012 | RETINOID X RECEPTOR-ALPHA NUCLEAR RECEPTOR, NUCLEUS, SIGNALING PROTEIN
4n5g:D (PRO293) to (LEU436) CRYSTAL STRUCTURE OF RXRA LBD COMPLEXED WITH A SYNTHETIC MODULATOR K8012 | RETINOID X RECEPTOR-ALPHA NUCLEAR RECEPTOR, NUCLEUS, SIGNALING PROTEIN
2jf9:B (THR371) to (LYS529) ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A TAMOXIFEN- SPECIFIC PEPTIDE ANTAGONIST | TRANSCRIPTION FACTOR, LIPID-BINDING, TRANSCRIPTION, TRANSCRIPTION REGULATION, LIGAND-BINDING DOMAIN (LBD), RECEPTOR, ZINC-FINGER, DNA-BINDING, STEROID-BINDING, NUCLEAR RECEPTOR, PEPTIDE ANTAGONIST, METAL-BINDING, NUCLEAR PROTEIN, PHOSPHORYLATION
4n8r:A (LEU294) to (LEU436) CRYSTAL STRUCTURE OF RXRA LBD COMPLEXED WITH A SYNTHETIC MODULATOR K- 8008 | RETINOID X RECEPTOR, ALPHA NUCLEAR RECEPTOR, NUCLEUS, SIGNALING PROTEIN
4n8r:B (LEU294) to (ARG421) CRYSTAL STRUCTURE OF RXRA LBD COMPLEXED WITH A SYNTHETIC MODULATOR K- 8008 | RETINOID X RECEPTOR, ALPHA NUCLEAR RECEPTOR, NUCLEUS, SIGNALING PROTEIN
4n8r:C (PRO293) to (GLU434) CRYSTAL STRUCTURE OF RXRA LBD COMPLEXED WITH A SYNTHETIC MODULATOR K- 8008 | RETINOID X RECEPTOR, ALPHA NUCLEAR RECEPTOR, NUCLEUS, SIGNALING PROTEIN
4n8r:D (PRO293) to (LEU436) CRYSTAL STRUCTURE OF RXRA LBD COMPLEXED WITH A SYNTHETIC MODULATOR K- 8008 | RETINOID X RECEPTOR, ALPHA NUCLEAR RECEPTOR, NUCLEUS, SIGNALING PROTEIN
1x7b:A (SER323) to (HIS475) CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH ERB-041 | ESTROGEN RECEPTOR, ESTROGEN RECEPTOR BETA, ER-BETA, ER, ESTROGEN, NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, AGONIST
1x7e:A (THR371) to (ASN532) CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR ALPHA COMPLEXED WITH WAY-244 | ESTROGEN RECEPTOR, ESTROGEN RECEPTOR BETA, ER-BETA, ER, ESTROGEN RECEPTOR ALPHA, ER-ALPHA, ESTROGEN, NUCLEAR RECEPT TRANSCRIPTION FACTOR, AGONIST
1kv6:B (SER293) to (MET419) X-RAY STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR ERR3 LIGAND- BINDING DOMAIN IN THE CONSTITUTIVELY ACTIVE CONFORMATION | TRANSCRIPTIONALLY ACTIVE CONFORMATION IN ABSENCE OF LIGAND, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, STRUCTURAL GENOMICS, GENE REGULATION
2nv7:A (SER323) to (ASN483) CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-555 | ESTROGEN RECEPTOR, ESTROGEN RECEPTOR BETA, ER-BETA, ER, ESTROGEN, NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, AGONIST, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
3jzb:A (GLU245) to (GLU391) CRYSTAL STRUCTURE OF TR-ALFA BOUND TO THE SELECTIVE THYROMIMETIC TRIAC | TRIAC, TR, THYROID, ENTROPY, DNA-BINDING, METAL-BINDING, NUCLEUS, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC-FINGER
1lbd:A (PRO293) to (HIS435) LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA | TRANSCRIPTION FACTOR, NUCLEAR RECEPTOR, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, STRUCTURAL GENOMICS
4oj9:A (HIS729) to (LYS883) CRYSTAL STRUCTURE OF T877A-AR-LBD BOUND WITH CO-REGULATOR PEPTIDE | ALPHA-HELIX, HORMONE/GROWTH FACTOR RECEPTOR, PHOSPHORYLATION, HORMONE RECEPTOR-PEPTIDE COMPLEX, SIGNAL TRANSDUCTION
1xls:A (PRO293) to (GLY443) CRYSTAL STRUCTURE OF THE MOUSE CAR/RXR LBD HETERODIMER BOUND TO TCPOBOP AND 9CRA AND A TIF2 PEPTIDE CONTAING THE THIRD LXXLL MOTIFS | LBD, NUCLEAR RECEPTOR, CAR, XENOBIOTIC, TRANSCRIPTION
1xls:B (PRO293) to (GLY443) CRYSTAL STRUCTURE OF THE MOUSE CAR/RXR LBD HETERODIMER BOUND TO TCPOBOP AND 9CRA AND A TIF2 PEPTIDE CONTAING THE THIRD LXXLL MOTIFS | LBD, NUCLEAR RECEPTOR, CAR, XENOBIOTIC, TRANSCRIPTION
1xls:C (PRO293) to (GLY443) CRYSTAL STRUCTURE OF THE MOUSE CAR/RXR LBD HETERODIMER BOUND TO TCPOBOP AND 9CRA AND A TIF2 PEPTIDE CONTAING THE THIRD LXXLL MOTIFS | LBD, NUCLEAR RECEPTOR, CAR, XENOBIOTIC, TRANSCRIPTION
1xls:D (PRO293) to (GLY443) CRYSTAL STRUCTURE OF THE MOUSE CAR/RXR LBD HETERODIMER BOUND TO TCPOBOP AND 9CRA AND A TIF2 PEPTIDE CONTAING THE THIRD LXXLL MOTIFS | LBD, NUCLEAR RECEPTOR, CAR, XENOBIOTIC, TRANSCRIPTION
1xnx:B (THR196) to (SER337) CRYSTAL STRUCTURE OF CONSTITUTIVE ANDROSTANE RECEPTOR | NUCLEAR RECEPTOR; CRYSTAL STRUCTURE, LIGAND RECEPTOR/TRANSRIPTION REGULATION COMPLEX
4oni:A (VAL371) to (GLY524) STRUCTURE OF HUMAN ORPHAN RECEPTOR LRH1 BOUND TO TWO BACTERIAL PHOSPHOLIPIDS | ALPHA HELICAL SANDWICH FOLD, NUCLEAR RECEPTOR, CO-FACTOR BINDING, NUCLEAR PROTEIN
1xqc:C (THR371) to (MET528) X-RAY STRUCTURE OF ERALPHA LBD BOUND TO A TETRAHYDROISOQUINOLINE SERM LIGAND AT 2.05A RESOLUTION | ALPHA-HELICAL SANDWICH, NUCLEAR HORMONE RECEPTOR, LIGAND BINDING DOMAIN
1xqc:D (THR371) to (LEU525) X-RAY STRUCTURE OF ERALPHA LBD BOUND TO A TETRAHYDROISOQUINOLINE SERM LIGAND AT 2.05A RESOLUTION | ALPHA-HELICAL SANDWICH, NUCLEAR HORMONE RECEPTOR, LIGAND BINDING DOMAIN
2zk1:B (ASP310) to (GLU460) HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA LIGAND BINDING DOMAIN COMPLEXED WITH 15-DEOXY-DELTA12,14- PROSTAGLANDIN J2 | ANTI PARALLEL HELIX SANDWICH, ACTIVATOR, ALTERNATIVE SPLICING, DIABETES MELLITUS, DISEASE MUTATION, DNA-BINDING, METAL-BINDING, NUCLEUS, OBESITY, PHOSPHOPROTEIN, POLYMORPHISM, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC, ZINC-FINGER
1xv9:B (ILE187) to (ILE333) CRYSTAL STRUCTURE OF CAR/RXR HETERODIMER BOUND WITH SRC1 PEPTIDE, FATTY ACID, AND 5B-PREGNANE-3,20-DIONE. | CAR, RXR, SRC1, PREGNANEDIONE, DNA BINDING PROTEIN
1xv9:C (PRO293) to (LYS440) CRYSTAL STRUCTURE OF CAR/RXR HETERODIMER BOUND WITH SRC1 PEPTIDE, FATTY ACID, AND 5B-PREGNANE-3,20-DIONE. | CAR, RXR, SRC1, PREGNANEDIONE, DNA BINDING PROTEIN
1xv9:D (PRO186) to (ILE333) CRYSTAL STRUCTURE OF CAR/RXR HETERODIMER BOUND WITH SRC1 PEPTIDE, FATTY ACID, AND 5B-PREGNANE-3,20-DIONE. | CAR, RXR, SRC1, PREGNANEDIONE, DNA BINDING PROTEIN
1m7w:C (LEU204) to (GLY353) HNF4A LIGAND BINDING DOMAIN WITH BOUND FATTY ACID | TRANSCRIPTION FACTOR
1xvp:A (PRO293) to (LYS440) CRYSTAL STRUCTURE OF CAR/RXR HETERODIMER BOUND WITH SRC1 PEPTIDE, FATTY ACID AND CITCO | CAR, RXR, CITCO, SRC1, DNA BINDING PROTEIN
1xvp:B (ILE187) to (ILE333) CRYSTAL STRUCTURE OF CAR/RXR HETERODIMER BOUND WITH SRC1 PEPTIDE, FATTY ACID AND CITCO | CAR, RXR, CITCO, SRC1, DNA BINDING PROTEIN
1xvp:C (PRO293) to (LYS440) CRYSTAL STRUCTURE OF CAR/RXR HETERODIMER BOUND WITH SRC1 PEPTIDE, FATTY ACID AND CITCO | CAR, RXR, CITCO, SRC1, DNA BINDING PROTEIN
4ozr:U (ILE227) to (LYS364) CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAINS OF THE BOVICOLA OVIS ECDYSONE RECEPTOR ECR/USP HETERODIMER (METHYLENE LACTAM CRYSTAL) | ECDYSONE RECEPTOR, USP, METHYLENE LACTAM, HETERODIMER, LIGAND BINDING DOMAIN, TRANSCRIPTION
1yin:A (THR371) to (SER527) HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 3F | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, ER-ALPHA, ANTAGONIST, HORMONE/GROWTH FACTOR RECEPTOR COMPLEX
1mzn:E (PRO2293) to (ILE2442) CRYSTAL STRUCTURE AT 1.9 ANGSTROEMS RESOLUTION OF THE HOMODIMER OF HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO THE SYNTHETIC AGONIST COMPOUND BMS 649 AND A COACTIVATOR PEPTIDE | TRANSCRIPTION, NUCLEAR RECEPTOR, RETINOIC ACID RECEPTORS, AGONIST
3a9e:A (PRO298) to (LEU441) CRYSTAL STRUCTURE OF A MIXED AGONIST-BOUND RAR-ALPHA AND ANTAGONIST- BOUND RXR-ALPHA HETERODIMER LIGAND BINDING DOMAINS | TRANSCRIPTION, NUCLEUS, RECEPTOR, TRANSCRIPTION REGULATION, STRUCTURAL GENOMICS, SPINE2-COMPLEXES, STRUCTURAL PROTEOMICS IN EUROPE
5di7:A (LEU379) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH AN METHYL-SUBSTITUTED A-CD RING ESTROGEN DERIVATIVE (1S,3AR,5S, 7AS)-5-(4-HYDROXY-2-METHYLPHENYL)-7A-METHYLOCTAHYDRO-1H-INDEN-1-OL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5di7:B (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH AN METHYL-SUBSTITUTED A-CD RING ESTROGEN DERIVATIVE (1S,3AR,5S, 7AS)-5-(4-HYDROXY-2-METHYLPHENYL)-7A-METHYLOCTAHYDRO-1H-INDEN-1-OL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5did:B (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A DIFLUORO-SUBSTITUTED A-CD RING ESTROGEN DERIVATIVE (1S,3AR,5S, 7AS)-5-(2,3-DIFLUORO-4-HYDROXYPHENYL)-7A-METHYLOCTAHYDRO-1H-INDEN-1- OL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5dig:B (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A TRIFLUOROMETHYL-SUBSTITUTED A-CD RING ESTROGEN DERIVATIVE (1S, 3AR,5S,7AS)-5-[4-HYDROXY-2-(TRIFLUOROMETHYL)PHENYL]-7A- METHYLOCTAHYDRO-1H-INDEN-1-OL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5dk9:A (VAL364) to (LYS529) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A PHENYLAMINO-SUBSTITUTED ETHYL TRIARYL-ETHYLENE DERIVATIVE 4, 4'-{2-[3-(PHENYLAMINO)PHENYL]BUT-1-ENE-1,1-DIYL}DIPHENOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5dke:A (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A 3-NAPHTHYL-SUBSTITUTED, METHYL, CIS-DIARYL-ETHYLENE COMPOUND 4,4'-[2-(NAPHTHALEN-2-YL)PROP-1-ENE-1,1-DIYL]DIPHENOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
4pld:A (LYS370) to (GLY524) HUMAN NUCLEAR RECEPTOR LIVER RECEPTOR HOMOLOGUE-1, LRH-1, IN ITS APO STATE BOUND TO A FRAGMENT OF HUMAN TIF-2 | NUCLEAR RECEPTOR, APO, TRANSCRIPTION
1z5x:E (GLY247) to (ASN401) HEMIPTERAN ECDYSONE RECEPTOR LIGAND-BINDING DOMAIN COMPLEXED WITH PONASTERONE A | ECDYSONE RECEPTOR, PONASTERONE A, NUCLEAR RECEPTOR, ECR, USP, ECDYSONE, HORMONE/GROWTH FACTOR RECEPTOR COMPLEX
1zdt:B (VAL291) to (ASN444) THE CRYSTAL STRUCTURE OF HUMAN STEROIDOGENIC FACTOR-1 | STEROIDOGENIC FACTOR-1, NUCLEAR RECEPTOR, PHOLPHOLIPID, PHOSPHATIDYLETHANOLAMINE, TRANSCRIPTION
5du5:B (LEU372) to (LYS531) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A DICHLORO-SUBSTITUTED, 3,4-DIARYLTHIOPHENE DIOXIDE CORE LIGAND | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5dug:A (LEU372) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A SULFOXIDE-BRIDGED OXABICYCLIC HEPTENE SULFONATE (SOBHS)-2 ANALOG PHENYL (1S,2S,4S,7S)-5,6-BIS(4-HYDROXY-2-METHYLPHENYL)-7- THIABICYCLO[2.2.1]HEPT-5-ENE-2-SULFONATE 7-OXIDE | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5dug:B (LEU372) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A SULFOXIDE-BRIDGED OXABICYCLIC HEPTENE SULFONATE (SOBHS)-2 ANALOG PHENYL (1S,2S,4S,7S)-5,6-BIS(4-HYDROXY-2-METHYLPHENYL)-7- THIABICYCLO[2.2.1]HEPT-5-ENE-2-SULFONATE 7-OXIDE | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
1zh7:A (VAL390) to (VAL541) STRUCTURAL AND BIOCHEMICAL BASIS FOR SELECTIVE REPRESSION OF THE ORPHAN NUCLEAR RECEPTOR LRH-1 BY SHP | PROTEIN-PEPTIDE COMPLEX, TRANSCRIPTION
1zh7:B (VAL390) to (GLY543) STRUCTURAL AND BIOCHEMICAL BASIS FOR SELECTIVE REPRESSION OF THE ORPHAN NUCLEAR RECEPTOR LRH-1 BY SHP | PROTEIN-PEPTIDE COMPLEX, TRANSCRIPTION
5dwi:A (THR371) to (LYS531) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A RESORCINYL 2-CHLORO-SUBSTITUTED DIARYL-IMINE ANALOG 4-[(E)- [(2-CHLOROPHENYL)IMINO](4-HYDROXYPHENYL)METHYL]BENZENE-1,3-DIOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5dwi:B (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A RESORCINYL 2-CHLORO-SUBSTITUTED DIARYL-IMINE ANALOG 4-[(E)- [(2-CHLOROPHENYL)IMINO](4-HYDROXYPHENYL)METHYL]BENZENE-1,3-DIOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5dxr:A (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH THE CYCLOFENIL DERIVATIVE 4,4'-{[(3R)-3- METHYLCYCLOHEXYLIDENE]METHANEDIYL}DIPHENOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5dxr:B (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH THE CYCLOFENIL DERIVATIVE 4,4'-{[(3R)-3- METHYLCYCLOHEXYLIDENE]METHANEDIYL}DIPHENOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5dy8:A (THR371) to (LYS529) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH THE CYCLOFENIL DERIVATIVE 4,4'-{[(3S)-3- ETHYLCYCLOHEXYLIDENE]METHANEDIYL}DIPHENOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5dyd:B (THR371) to (LYS529) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH THE CYCLOFENIL DERIVATIVE 4,4'-{[(3S)-3-(METHYLSULFANYL) CYCLOHEXYLIDENE]METHANEDIYL}DIPHENOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5dz3:A (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH THE CYCLOFENIL DERIVATIVE 4,4'-{[4-(FLUOROMETHYL) CYCLOHEXYLIDENE]METHANEDIYL}DIPHENOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5dzi:B (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH THE CYCLOFENIL DERIVATIVE 4,4'-{[(3S)-3-(2-HYDROXYETHYL) CYCLOHEXYLIDENE]METHANEDIYL}DIPHENOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5e0w:A (THR371) to (CYS530) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH THE CYCLOFENIL DERIVATIVE 4,4'-{[(3S)-3-(4-HYDROXYPHENYL) CYCLOHEXYLIDENE]METHANEDIYL}DIPHENOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5e0w:B (THR371) to (SER527) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH THE CYCLOFENIL DERIVATIVE 4,4'-{[(3S)-3-(4-HYDROXYPHENYL) CYCLOHEXYLIDENE]METHANEDIYL}DIPHENOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
4q50:G (THR371) to (MET528) THE ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN D538G MUTANT IN COMPLEX WITH 4-HYDROXYTAMOXIFEN | ACQUIRED SERM-RESISTANCE, BREAST CANCER, ACTIVATING MUTATION, SERM-ER STRUCTURE, ALPHA HELIX, NUCLEAR HORMONE RECEPTOR, HORMONE BINDING PROTEIN
2acl:G (PRO293) to (LEU433) LIVER X-RECEPTOR ALPHA LIGAND BINDING DOMAIN WITH SB313987 | NUCLEAR HORMONE RECEPTOR LIGAND BINDING DOMAIN TRANSCRIPTION FACTOR THREE LAYERED A-HELIX FOLD
4rak:A (GLY296) to (SER436) CRYSTAL STRUCTURE OF NUCLEAR RECEPTOR SUBFAMILY 1, GROUP H, MEMBER 2 (LXRB) COMPLEXED WITH PARTIAL AGONIST | NHR, NR1H2, LXR-B, LXRB, UNR, NER-I, RIP15, NER, LIGAND BINDING DOMAIN, NUCLEAR HORMONE RECEPTOR, RXR, TRANSCRIPTION-AGONIST COMPLEX
3noa:B (LEU311) to (LYS458) CRYSTAL STRUCTURE OF HUMAN PPAR-GAMMA LIGAND BINDING DOMAIN COMPLEX WITH A POTENCY IMPROVED AGONIST | HYPOGLYCEMIC AGENTS, MODELS, MOLECULAR, PPAR ALPHA, PPAR GAMMA, PROTEIN ISOFORMS, QUINOLINES, STRUCTURE-ACTIVITY RELATIONSHIP, THIAZOLIDINEDIONES, TRANSCRIPTION
3nsq:A (PRO293) to (GLU434) CRYSTAL STRUCTURE OF TETRAMERIC RXRALPHA-LBD COMPLEXED WITH ANTAGONIST DANTHRON | NUCLEAR RECEPTOR RETINOIC X RECEPOR ALPHA LIGAND BINDING DOMAIN ANTAGONIST DANTHRON, TRANSCRIPTION
3ctb:A (PRO268) to (PRO419) TETHERED PXR-LBD/SRC-1P APOPROTEIN | PXR,SRC-1, TETHERED, ENGINEERED, DRUG-DRUG INTERACTIONS, DNA-BINDING, METAL-BINDING, NUCLEUS, RECEPTOR, TRANSCRIPTION REGULATION, ZINC- FINGER, TRANSCRIPTION, TRANSFERASE
3ctb:B (PRO268) to (HIS418) TETHERED PXR-LBD/SRC-1P APOPROTEIN | PXR,SRC-1, TETHERED, ENGINEERED, DRUG-DRUG INTERACTIONS, DNA-BINDING, METAL-BINDING, NUCLEUS, RECEPTOR, TRANSCRIPTION REGULATION, ZINC- FINGER, TRANSCRIPTION, TRANSFERASE
4s0t:B (LEU240) to (HIS418) STRUCTURE OF HUMAN PREGNANE X RECEPTOR LIGAND BINDING DOMAIN BOUND WITH ADNECTIN-1 AND COMPOUND-1 | NUCLEAR RECEPTOR, MULTIPLE BINDING MODES, XENOBIOTIC, PROMISCUOUS, NUCLEAR HORMONE RECEPTOR, TRANSCRIPTION
3d24:A (SER253) to (LEU383) CRYSTAL STRUCTURE OF LIGAND-BINDING DOMAIN OF ESTROGEN- RELATED RECEPTOR ALPHA (ERRALPHA) IN COMPLEX WITH THE PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR COACTIVATOR- 1ALPHA BOX3 PEPTIDE (PGC-1ALPHA) | NUCLEAR RECEPTOR, LIGAND BINDING DOMAIN, COACTIVATOR, DNA- BINDING, METAL-BINDING, NUCLEUS, PHOSPHOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC, ZINC-FINGER, POLYMORPHISM, RNA-BINDING, STRUCTURAL GENOMICS, STRUCTURAL PROTEOMICS IN EUROPE, SPINE
4tuz:A (THR371) to (ASN532) CRYSTAL STRUCTURE OF HERA-LBD (Y537S) IN COMPLEX WITH ALPHA-ZEARALENOL | NUCLEAR HORMONE RECEPTOR LIGAND BINDING DOMAIN ENDOCRINE DISRUPTOR ENVIRONMENTAL COMPOUND, NUCLEAR PROTEIN
4tv1:B (THR371) to (LYS531) CRYSTAL STRUCTURE OF HERA-LBD (Y537S) IN COMPLEX WITH PROPYLPARABEN | NUCLEAR HORMONE RECEPTOR, LIGAND BINDING DOMAIN, ENDOCRINE DISRUPTOR, ENVIRONMENTAL COMPOUND, HORMONE RECEPTOR
5hjp:A (PRO364) to (GLY514) IDENTIFICATION OF LXRBETA SELECTIVE AGONISTS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | AGONIST, ALZHEIMER'S, SIGNALING PROTEIN
5hjp:D (GLY296) to (ARG411) IDENTIFICATION OF LXRBETA SELECTIVE AGONISTS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | AGONIST, ALZHEIMER'S, SIGNALING PROTEIN
4dma:B (THR1371) to (ASN1532) CRYSTAL STRUCTURE OF ERA LBD IN COMPLEX WITH RU100132 | TRANSCRIPTION, NUCLEAR RECEPTOR, ER, ESTROGEN RECEPTOR, ALPHA HELICAL SANDWICH, TRANSCRIPTION FACTOR, ESTRADIOL, TRANSCRIPTION-PROTEIN BINDING-AGONIST COMPLEX
3pcu:A (PRO293) to (GLY443) CRYSTAL STRUCTURE OF HUMAN RETINOIC X RECEPTOR ALPHA LIGAND-BINDING DOMAIN COMPLEXED WITH LX0278 AND SRC1 PEPTIDE | NUCLEAR RECEPTOR RXRALPHA, LIGAND-BINDING DOMAIN, TRANSCRIPTION- TRANSCRIPTION REGULATOR COMPLEX
5i4v:A (GLY296) to (ASP446) DISCOVERY OF NOVEL, ORALLY EFFICACIOUS LIVER X RECEPTOR (LXR) BETA AGONISTS | LXRBETA-LBD, RXRBETA-LBD, HETERODIMER, AGONIST, DNA BINDING PROTEIN
5i4v:E (GLY296) to (ARG411) DISCOVERY OF NOVEL, ORALLY EFFICACIOUS LIVER X RECEPTOR (LXR) BETA AGONISTS | LXRBETA-LBD, RXRBETA-LBD, HETERODIMER, AGONIST, DNA BINDING PROTEIN
3plz:B (VAL371) to (GLY524) HUMAN LRH1 LBD BOUND TO GR470 | ALPHA HELICAL SANDWHICH, NUCLEAR RECEPTOR, FAMILY FIVE, TRANSCRIPTION FACTOR, CO-ACTIVATOR, TRANSCRIPTION-RECEPTOR-AGONIST COMPLEX
4fhi:A (THR283) to (PRO434) DEVELOPMENT OF SYNTHETICALLY ACCESSIBLE NON-SECOSTEROIDAL HYBRID MOLECULES COMBINING VITAMIN D RECEPTOR AGONISM AND HISTONE DEACETYLASE INHIBITION | LIGAND BINDING DOMAIN ALPHA HELICAL SANDWICH, ALPHA HELICAL SANDWICH, TRANSCRIPTION FACTOR, DNA COREGULATORS, PHOSPHORYLATION, NUCLEUS, TRANSCRIPTION-PROTEIN BINDING-INHIBITOR COMPLEX
3r29:A (PRO293) to (LEU441) CRYSTAL STRUCTURE OF RXRALPHA LIGAND-BINDING DOMAIN COMPLEXED WITH COREPRESSOR SMRT2 | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND-BINDING DOMAIN, TRANSCRIPTION
3r8d:A (PRO268) to (HIS418) ACTIVATION OF THE HUMAN NUCLEAR XENOBIOTIC RECEPTOR PXR BY THE REVERSE TRANSCRIPTASE-TARGETED ANTI-HIV DRUG PNU-142721 | NUCLEAR RECEPTOR, PXR, XENOBIOTIC, LIGAND BINDING DOMAIN, TRANSCRIPTION REGULATION, XENOBIOTICS, ENDOBIOTICS, TRANSCRIPTION
4g20:A (THR283) to (GLN433) STRUCTURAL BASIS FOR THE ACCOMMODATION OF BIS- AND TRIS-AROMATIC DERIVATIVES IN VITAMIN D NUCLEAR RECEPTOR | VDR, TRANSCRIPTION REGULATION, NUCLEAR RECEPTOR, ALPHA HELICAL SANDWICH, LIGAND, DNA, PHOSPHORYLATION, NUCLEUS, TRANSCRIPTION- TRANSCRIPTION INHIBITOR COMPLEX
5jy3:A (GLY296) to (SER436) CRYSTAL STRUCTURE OF LXRBETA (NUCLEAR RECEPTOR SUBFAMILY 1, GROUP H, MEMBER 2) COMPLEXED WITH BMS-852927 | NHR, NR1H2, LXR-B, LXRB, UNR, NER-I, RIP15, NER, TRANSCRIPTION
5kcc:A (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH OXABICYCLIC HEPTENE SULFONAMIDE (OBHS-N) | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
5kce:A (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH AN N-METHYL, 2-CHLOROBENZYL OBHS-N DERIVATIVE | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, SIGNALING PROTEIN, TRANSCRIPTION
5kd9:B (VAL364) to (SER527) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH AN N-TRIFLUOROETHYL 4-CHLOROBENZYL OBHS-N DERIVATIVE | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
1a52:A (LEU379) to (LYS531) ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN COMPLEXED TO ESTRADIOL | RECEPTOR, ESTROGEN, LIGAND, TRANSCRIPTION REGULATION
2qmv:A (ASP310) to (LYS458) HIGH RESOLUTION STRUCTURE OF PEROXISONE PROLIFERATION-ACTIVATED RECEPTOR GAMMA AND CHARACTERISATION OF ITS INTERACTION WITH THE CO- ACTIVATOR TRANSCRIPTIONAL INTERMEDIARY FACTOR 2 | PEROXISOME PROFILERATION ACTIVATED RECEPTOR GAMMA, PPARG, TRANSCRIPTIONAL INTERMEDIARY FACTOR 2 (TIF2), PROTEIN STRUCTURE, ACTIVATOR, DIABETES MELLITUS, DISEASE MUTATION, DNA-BINDING, METAL- BINDING, NUCLEUS, OBESITY, PHOSPHORYLATION, TRANSCRIPTION REGULATION, ZINC-FINGER, TRANSCRIPTION REGULATOR
1pk5:A (LYS389) to (GLY543) CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR LRH-1 | NUCLEAR RECEPTOR, LIGAND-BINDING DOMAIN, LRH-1, GENE REGULATION
1pk5:B (LYS389) to (GLY543) CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR LRH-1 | NUCLEAR RECEPTOR, LIGAND-BINDING DOMAIN, LRH-1, GENE REGULATION
1q4x:A (CYS298) to (CYS446) CRYSTAL STRUCTURE OF HUMAN THYROID HORMONE RECEPTOR BETA LBD IN COMPLEX WITH SPECIFIC AGONIST GC-24 | CONFORMATIONAL CHANGE IN TWO FRAMEWORK HELICES UPON LIGAND BINDING, TRANSCRIPTION
1fm6:A (PRO293) to (LEU441) THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND ROSIGLITAZONE AND CO-ACTIVATOR PEPTIDES. | THE HETERODIMER OF THE NUCLEAR RECEPTOR LIGAND BINDING DOMAINS OF RXRALPHA AND PPARGAMMA BOUND RESPECTIVELY WITH 9-CIS RETINOIC ACID AND ROSIGLITAZONE AND CO-ACTIVATOR PEPTIDES, TRANSCRIPTION
1fm6:U (PRO293) to (ILE442) THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND ROSIGLITAZONE AND CO-ACTIVATOR PEPTIDES. | THE HETERODIMER OF THE NUCLEAR RECEPTOR LIGAND BINDING DOMAINS OF RXRALPHA AND PPARGAMMA BOUND RESPECTIVELY WITH 9-CIS RETINOIC ACID AND ROSIGLITAZONE AND CO-ACTIVATOR PEPTIDES, TRANSCRIPTION
4kzm:B (SER431) to (GLU579) CRYSTAL STRUCTURE OF TR3 LBD S553A MUTANT | ORPHAN NUCLEAR RECEPTOR, TRANSCRIPTION
4lnw:A (ASP246) to (GLU391) CRYSTAL STRUCTURE OF TR-ALPHA BOUND TO T3 IN A SECOND SITE | MAINLY ALPHA ORTHOGONAL BUNDLE, TRANSCRIPTION FACTOR, TRANSCRIPTION
3k6p:A (SER349) to (TYR496) ESTROGEN RELATED RECEPTOR ALPHA IN COMPLEX WITH AN ETHER BASED LIGAND | ESTROGEN RELATED RECEPTOR ALPHA, DNA-BINDING, ISOPEPTIDE BOND, METAL- BINDING, NUCLEUS, PHOSPHOPROTEIN, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC-FINGER, HORMONE RECEPTOR
1n46:A (CYS298) to (GLU445) CRYSTAL STRUCTURE OF HUMAN TR BETA LIGAND-BINDING DOMAIN COMPLEXED WITH A POTENT SUBTYPE-SELECTIVE THYROMIMETIC | TRANSCRIPTION
5dkb:A (THR371) to (LYS529) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A 3-METHYLPHENYLAMINO-SUBSTITUTED ETHYL TRIARYL-ETHYLENE DERIVATIVE 4,4'-(2-{3-[(3-METHYLPHENYL)AMINO]PHENYL}BUT-1-ENE-1,1- DIYL)DIPHENOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
4pps:A (THR371) to (ASN532) CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH AN A-CD RING ESTROGEN DERIVATIVE | NUCLEAR HORMONE RECEPTOR, TRANSCRIPTION FACTOR, LIGAND-BINDING, NUCLEUS, PROTEIN BINDING
5e14:A (THR371) to (TYR526) CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH THE CYCLOFENIL DERIVATIVE 4,4'-{[(3R)-3- PHENYLCYCLOHEXYLIDENE]METHANEDIYL}DIPHENOL | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND BINDING, PROTEIN- LIGAND COMPLEX, TRANSCRIPTION
4re8:B (SER100) to (ASP249) CRYSTAL STRUCTURE OF TR3 LBD IN COMPLEX WITH MOLECULE 5 | LBD, TRANSCRIPTION
4rze:B (SER100) to (ASP249) CRYSTAL STRUCTURE ANALYSIS OF THE NUR77 LIGAND BINDING DOMAIN, L437W, D594E MUTANT | TRANSCRIPTION
4rzf:B (SER100) to (ASP249) CRYSTAL STRUCTURE ANALYSIS OF THE NUR77 LIGAND BINDING DOMAIN, S441W MUTANT | TRANSCRIPTION
3r2a:A (PRO293) to (GLY443) CRYSTAL STRUCTURE OF RXRALPHA LIGAND-BINDING DOMAIN COMPLEXED WITH COREPRESSOR SMRT2 AND ANTAGONIST RHEIN | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND-BINDING DOMAIN, TRANSCRIPTION
3r2a:C (PRO293) to (GLY443) CRYSTAL STRUCTURE OF RXRALPHA LIGAND-BINDING DOMAIN COMPLEXED WITH COREPRESSOR SMRT2 AND ANTAGONIST RHEIN | NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, LIGAND-BINDING DOMAIN, TRANSCRIPTION