1a1c:A   (TRP151) to   (HIS236)  C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(N-ME(- (CH2)3-CYCLOPENTYL))  |   COMPLEX (TRANSFERASE/PEPTIDE) 
1a1e:A   (TRP151) to   (HIS236)  C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(3- BUTYLPIPERIDINE)  |   COMPLEX (TRANSFERASE/PEPTIDE) 
1a1e:B   (TRP151) to   (HIS236)  C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(3- BUTYLPIPERIDINE)  |   COMPLEX (TRANSFERASE/PEPTIDE) 
4h1o:A     (TRP6) to    (MET82)  CRYSTAL STRUCTURE OF THE TYROSINE PHOSPHATASE SHP-2 WITH D61G MUTATION  |   ALPHA/BETA PROTEINS, SH2 DOMAIN, PHOSPHATASE DOMAIN, TYROSINE PHOSPHATASE SHP-2, HYDROLASE 
4h1o:A   (TRP112) to   (ASN200)  CRYSTAL STRUCTURE OF THE TYROSINE PHOSPHATASE SHP-2 WITH D61G MUTATION  |   ALPHA/BETA PROTEINS, SH2 DOMAIN, PHOSPHATASE DOMAIN, TYROSINE PHOSPHATASE SHP-2, HYDROLASE 
2oq1:A   (TRP165) to   (LYS244)  TANDEM SH2 DOMAINS OF ZAP-70 WITH 19-MER ZETA1 PEPTIDE  |   TANDEM SH2 DOMAINS, ZAP-70, TYROSINE KINASE, TRANSFERASE 
4h34:A     (TRP6) to    (GLU83)  CRYSTAL STRUCTURE OF THE TYROSINE PHOSPHATASE SHP-2 WITH Q506P MUTATION  |   ALPHA/BETA PROTEINS, SH2 DOMAIN, PHOSPHATASE DOMAIN, TYROSINE PHOSPHATASE SHP-2, HYDROLASE 
4h34:A   (TRP112) to   (ASN200)  CRYSTAL STRUCTURE OF THE TYROSINE PHOSPHATASE SHP-2 WITH Q506P MUTATION  |   ALPHA/BETA PROTEINS, SH2 DOMAIN, PHOSPHATASE DOMAIN, TYROSINE PHOSPHATASE SHP-2, HYDROLASE 
2b3o:A   (TRP110) to   (THR197)  CRYSTAL STRUCTURE OF HUMAN TYROSINE PHOSPHATASE SHP-1  |   PROTEIN TYROSINE PHOSPHATASE, SHP-1, SIGNALING, HYDROLASE 
2ozo:A   (TRP163) to   (LYS240)  AUTOINHIBITED INTACT HUMAN ZAP-70  |   INACTIVE ZAP-70, TANDEM SH2, AUTOINHIBITION, ITAM, HYDROGEN BONDING NETWORK, TCR SIGNALING, TRANSFERASE 
1nzv:B   (TRP254) to   (HIS339)  CRYSTAL STRUCTURE OF SRC SH2 DOMAIN BOUND TO DOUBLY PHOSPHORYLATED PEPTIDE PQPYIPYVPA  |   SH2 DOMAIN, PHOSPHOTYROSINE, TRANSFERASE 
1bhf:A   (TRP127) to   (ALA212)  P56LCK SH2 DOMAIN INHIBITOR COMPLEX  |   SH2 DOMAIN, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
1bhh:A   (TRP127) to   (ASN211)  FREE P56LCK SH2 DOMAIN  |   SH2 DOMAIN, PHOSPHORYLATION, TRANSFERASE 
1bhh:B   (TRP127) to   (ALA212)  FREE P56LCK SH2 DOMAIN  |   SH2 DOMAIN, PHOSPHORYLATION, TRANSFERASE 
1bkl:A     (TRP5) to    (HIS90)  SELF-ASSOCIATED APO SRC SH2 DOMAIN  |   V-SRC SH2 DOMAIN, PHOSPHOTYROSINE RECOGNITION DOMAIN, PP60 SRC SH2 DOMAIN 
4x6s:A   (TRP431) to   (GLN513)  GRB7 SH2 DOMAIN WITH PHOSPHOTYROSINE MIMETIC INHIBITOR PEPTIDE  |   SRC HOMOLOGY DOMAIN, INHIBITOR, PHOSPHOTYROSINE BINDING POCKET, SIGNALING PROTEIN-INHIBITOR COMPLEX 
3s8l:A    (TRP60) to   (ARG136)  PROTEIN-LIGAND INTERACTIONS: THERMODYNAMIC EFFECTS ASSOCIATED WITH INCREASING HYDROPHOBIC SURFACE AREA  |   GRB2 SH2 DOMAIN, PHOSPHOTYROSINE-CONTAINING TRIPEPTIDE, SIGNALING PROTEIN-ANTAGONIST COMPLEX 
3s8o:A    (TRP60) to   (ARG136)  CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A PYXN- DERIVED TRIPEPTIDE  |   GRB2 SH2 DOMAIN, PHOSPHOTYROSINE-CONTAINING TRIPEPTIDE, SIGNALING PROTEIN-ANTAGONIST COMPLEX 
1cwd:L     (TRP5) to    (ALA90)  HUMAN P56LCK TYROSINE KINASE COMPLEXED WITH PHOSPHOPEPTIDE  |   PHOSPHOTRANSFERASE, COMPLEX (PHOSPHOTRANSFERASE-PEPTIDE), PHOSPHOTRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
1d1z:C  (VAL3006) to  (PHE3087)  CRYSTAL STRUCTURE OF THE XLP PROTEIN SAP  |   SH2 DOMAINS, GENE REGULATION 
4xz0:A    (PHE10) to    (ASP90)  ZAP-70-TSH2:COMPOUND-A COMPLEX  |   TYROSINE KINASE, CYSTEINE ADDUCT, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4xz0:A   (TRP163) to   (LYS240)  ZAP-70-TSH2:COMPOUND-A COMPLEX  |   TYROSINE KINASE, CYSTEINE ADDUCT, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4xz1:A    (PHE10) to    (ASP90)  ZAP-70-TSH2:COMPOUND-B ADDUCT  |   TYROSINE KINASE, CYSTEINE ADDUCT, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4xz1:A   (TRP163) to   (LEU241)  ZAP-70-TSH2:COMPOUND-B ADDUCT  |   TYROSINE KINASE, CYSTEINE ADDUCT, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
1qg1:E     (TRP5) to    (THR83)  GROWTH FACTOR RECEPTOR BINDING PROTEIN SH2 DOMAIN COMPLEXED WITH AN SHC-DERIVED PEPTIDE  |   SIGNAL TRANSDUCTION, SH2 DOMAIN, PHOSPHOTYROSYL PEPTIDE, COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE), HORMONE/GROWTH FACTOR COMPLEX 
2rmx:A     (TRP8) to    (THR95)  SOLUTION STRUCTURE OF THE SHP-1 C-TERMINAL SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM NKG2A  |   SH2 DOMAIN, PROTEIN-PEPTIDE COMPLEX, PHOSPHORYLATED PEPTIDE RECOGNITION, PHOSPHOTYROSINE BINDING DOMAIN, SIGNAL TRANSDUCTION, ALTERNATIVE SPLICING, CYTOPLASM, HYDROLASE, NUCLEUS, PHOSPHOPROTEIN, PROTEIN PHOSPHATASE, GLYCOPROTEIN, LECTIN, MEMBRANE, RECEPTOR, SIGNAL-ANCHOR, TRANSMEMBRANE, SIGNALING PROTEIN, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI 
2ror:A    (LEU27) to   (SER106)  SOLUTION STRUCTURE OF THE VAV1 SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM SLP76  |   SH2 DOMAIN, PROTEIN-PEPTIDE COMPLEX, PHOSPHORYLATED PEPTIDE RECOGNITION, PHOSPHOTYROSINE BINDING DOMAIN, SIGNAL TRANSDUCTION, GUANINE-NUCLEOTIDE RELEASING FACTOR, METAL- BINDING, PHORBOL-ESTER BINDING, PHOSPHOPROTEIN, PROTO- ONCOGENE, SH3 DOMAIN, ZINC, ZINC-FINGER, SIGNALING PROTEIN, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI 
2shp:A   (TRP112) to   (ASN200)  TYROSINE PHOSPHATASE SHP-2  |   TYROSINE PHOSPHATASE, INSULIN SIGNALING, SH2 PROTEIN 
2shp:B   (TRP112) to   (ASN200)  TYROSINE PHOSPHATASE SHP-2  |   TYROSINE PHOSPHATASE, INSULIN SIGNALING, SH2 PROTEIN 
1f2f:A   (TRP148) to   (HIS233)  SRC SH2 THREF1TRP MUTANT  |   SRC, SH2 DOMAIN, SPECIFICITY SWITCH, TRANSFERASE 
1r1q:A    (TRP60) to   (SER138)  STRUCTURAL BASIS FOR DIFFERENTIAL RECOGNITION OF TYROSINE PHOSPHORYLATED SITES IN THE LINKER FOR ACTIVATION OF T CELLS (LAT) BY THE ADAPTOR PROTEIN GADS  |   SH2, GADS, LAT, PHOSPHOPEPTIDE, PEPTIDE BINDING PROTEIN 
1r1q:B    (TRP60) to   (ARG135)  STRUCTURAL BASIS FOR DIFFERENTIAL RECOGNITION OF TYROSINE PHOSPHORYLATED SITES IN THE LINKER FOR ACTIVATION OF T CELLS (LAT) BY THE ADAPTOR PROTEIN GADS  |   SH2, GADS, LAT, PHOSPHOPEPTIDE, PEPTIDE BINDING PROTEIN 
1fbz:B   (TRP205) to   (ALA290)  STRUCTURE-BASED DESIGN OF A NOVEL, OSTEOCLAST-SELECTIVE, NONPEPTIDE SRC SH2 INHIBITOR WITH IN VIVO ANTI-RESORPTIVE ACTIVITY  |   SH2 DOMAIN, NONPEPTIDE INHIBITOR, TRANSFERASE 
2el8:A    (CYS24) to   (SER106)  SOLUTION STRUCTURE OF THE HUMAN STAP2 SH2 DOMAIN  |   SH2 DOMAIN, PHOSPHOTYROSINE BINDING DOMAIN, PROTEIN TYROSINE KINASE, SIGNAL TRANSDUCTION, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, SIGNALING PROTEIN 
2eo6:A    (TRP25) to   (GLN109)  SOLUTION STRUCTURE OF THE SH2 DOMAIN FROM MOUSE B-CELL LINKER PROTEIN BLNK  |   SH2, CYTOPLASMIC ADAPTER PROTEIN, B-CELL ADAPTER CONTAINING SH2 DOMAIN PROTEIN, B-CELL ADAPTER CONTAINING SRC HOMOLOGY 2 DOMAIN PROTEIN, SRC HOMOLOGY 2 DOMAIN-CONTAINING LEUKOCYTE PROTEIN OF 65 KDA, SLP-65, LYMPHOCYTE ANTIGEN 57, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, SIGNALING PROTEIN 
4k2r:A   (TRP163) to   (ALA243)  STRUCTURAL BASIS FOR ACTIVATION OF ZAP-70 BY PHOSPHORYLATION OF THE SH2-KINASE LINKER  |   KINASE DOMAIN, SH2 DOMAIN, TRANSFERASE, ATP BINDING, CYTOPLAM 
2etz:A    (TRP11) to    (ASN97)  THE NMR MINIMIZED AVERAGE STRUCTURE OF THE ITK SH2 DOMAIN BOUND TO A PHOSPHOPEPTIDE  |   CIS/TRANS ISOMERIZATION, INTERLEUKIN-2 TYROSINE KINASE, ITK, T-CELL SPECIFIC KINASE, TSK, SRC HOMOLOGY 2, SH2, PROLINE, PHOSPHOTYROSINE BINDING, TRANSFERASE 
1fmk:A   (TRP148) to   (HIS233)  CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC  |   SRC, TYROSINE KINASE, PHOSPHORYLATION, SH2, SH3, PHOSPHOTYROSINE, PROTO-ONCOGENE, PHOSPHOTRANSFERASE 
1rja:A     (SER1) to    (GLN84)  SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF THE NONRECEPTOR TYROSINE KINASE PTK6/BRK SH2 DOMAIN  |   HUMAN PROTEIN TYROSINE KINASE-6 (PTK6/BRK), SRC HOMOLOGY 2(SH2) DOMAIN, SOLUTION STRUCTURE, BACKBONE DYNAMICS, TRANSFERASE 
1ghu:A    (TRP60) to   (THR138)  NMR SOLUTION STRUCTURE OF GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 (GRB2) SH2 DOMAIN, 24 STRUCTURES  |   SRC HOMOLOGY 2 DOMAIN, GRB2, SH2 
1shb:A     (TRP5) to    (SER88)  CRYSTAL STRUCTURE OF THE PHOSPHOTYROSINE RECOGNITION DOMAIN SH2 OF V-SRC COMPLEXED WITH TYROSINE-PHOSPHORYLATED PEPTIDES  |   PHOSPHOTRANSFERASE 
1gri:A    (TRP60) to   (SER139)  GRB2  |   SH2, SH3, SIGNAL TRANSDUCTION ADAPTOR 
1gri:B    (TRP60) to   (ARG136)  GRB2  |   SH2, SH3, SIGNAL TRANSDUCTION ADAPTOR 
3imj:B    (TRP60) to   (ARG136)  CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A CYCLOPROPYL-CONSTRAINED AC-PTYR-ILE-ASN-NH2 TRIPEPTIDE MIMIC  |   LIGAND PREORGANIZATION, PEPTIDE MIMICS, GOLGI APPARATUS, HOST-VIRUS INTERACTION, PHOSPHOPROTEIN, SH2 DOMAIN, SH3 DOMAIN, SIGNALING PROTEIN-PSEUDOPEPTIDE LIGAND COMPLEX, SIGNALING PROTEIN-PEPTIDE COMPLEX 
3in7:C    (TRP60) to   (ARG136)  CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A CYCLOPROPYL-CONSTRAINED AC-PY-Q-N-NH2 TRIPEPTIDE MIMIC  |   LIGAND PREORGANIZATION, PEPTIDE MIMICS, GOLGI APPARATUS, HOST-VIRUS INTERACTION, PHOSPHOPROTEIN, SH2 DOMAIN, SH3 DOMAIN, SIGNALING PROTEIN-PSEUDOPEPTIDE LIGAND COMPLEX, SIGNALING PROTEIN-PEPTIDE COMPLEX 
1tze:E    (TRP60) to   (ARG136)  SIGNAL TRANSDUCTION ADAPTOR GROWTH FACTOR, GRB2 SH2 DOMAIN COMPLEXED WITH PHOSPHOTYROSYL HEPTAPEPTIDE LYS-PRO-PHE-PTYR-VAL-ASN-VAL-NH2 (KFPPYVNC-NH2)  |   SIGNAL TRANSDUCTION ADAPTOR GROWTH FACTOR BOUND PROTEIN 2 (GRB2) SRC HOMOLOGY 2 DOMAIN (SH2), PHOSPHOTYROSYL HEPTAPEPTIC LIGAND, COMPLEX (SIGNAL TRANSDUCTION-PEPTIDE), COMPLEX (SIGNAL TRANSDUCTION-PEPTIDE) COMPLEX 
4lue:A   (TRP149) to   (GLY234)  CRYSTAL STRUCTURE OF HCK IN COMPLEX WITH 7-[TRANS-4-(4- METHYLPIPERAZIN-1-YL)CYCLOHEXYL]-5-(4-PHENOXYPHENYL)-7H-PYRROLO[2,3- D]PYRIMIDIN-4-AMINE (RESULTING FROM DISPLACEMENT OF SKF86002)  |   COCRYSTALLIZATION, SKF86002, FLUORESCENCE, INHIBITOR SCREENING, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
2huw:A    (TRP60) to   (ARG136)  X-RAY CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN COMPLEXED TO A CONSTRAINED AND CYCLOPROPANE-DERIVED LIGAND  |   CYLCOPROPANE, CONTRAINED, GRB2, SH2, PREORGANIZATION,, HORMONE/GROWTH FACTOR COMPLEX 
1ijr:A     (TRP5) to    (ALA90)  CRYSTAL STRUCTURE OF LCK SH2 COMPLEXED WITH NONPEPTIDE PHOSPHOTYROSINE MIMETIC  |   TYROSINE-PROTEIN KINASE, TRANSFERASE/SIGNALING PROTEIN COMPLEX 
4m4z:A    (TRP94) to   (ALA180)  SH3 AND SH2 DOMAINS OF HUMAN SRC-LIKE ADAPTOR PROTEIN 2 (SLAP2)  |   SH3 AND SH2 DOMAINS, ADAPTOR, SIGNALING PROTEIN 
3wa4:A    (TRP60) to   (ARG136)  GRB2 SH2 DOMAIN/CD28-DERIVED PEPTIDE COMPLEX  |   GRB2 SH2 DOMAIN, SIGNALING PROTEIN 
1ju5:A    (TRP13) to   (ILE106)  TERNARY COMPLEX OF AN CRK SH2 DOMAIN, CRK-DERIVED PHOPHOPEPTIDE, AND ABL SH3 DOMAIN BY NMR SPECTROSCOPY  |   CRK, SH2, ABL, SH3, ADAPTOR PROTEIN, PHOSPHOPEPTIDE, NMR, PROTEIN BINDING/TRANSFERASE COMPLEX 
5bo4:G    (TRP48) to   (LYS134)  STRUCTURE OF SOCS2:ELONGIN C:ELONGIN B FROM DMSO-TREATED CRYSTALS  |   SIGNALING PROTEIN, UBIQUITIN LIGASE, SUPPRESSOR OF CYTOKINE SIGNALLING 
5bo4:J    (TRP48) to   (LYS134)  STRUCTURE OF SOCS2:ELONGIN C:ELONGIN B FROM DMSO-TREATED CRYSTALS  |   SIGNALING PROTEIN, UBIQUITIN LIGASE, SUPPRESSOR OF CYTOKINE SIGNALLING 
5bo4:P    (TRP48) to   (LYS134)  STRUCTURE OF SOCS2:ELONGIN C:ELONGIN B FROM DMSO-TREATED CRYSTALS  |   SIGNALING PROTEIN, UBIQUITIN LIGASE, SUPPRESSOR OF CYTOKINE SIGNALLING 
2kno:A    (TRP22) to   (HIS114)  NMR SOLUTION STRUCTURE OF SH2 DOMAIN OF THE HUMAN TENSIN LIKE C1 DOMAIN CONTAINING PHOSPHATASE (TENC1)  |   SH2 DOMAIN, TENC1, SOLUTION STRUCTURE, TENSIN2, CELL JUNCTION, CELL MEMBRANE, HYDROLASE, MEMBRANE, METAL-BINDING, PHORBOL-ESTER BINDING, PHOSPHOPROTEIN, PROTEIN PHOSPHATASE, ZINC-FINGER 
2lnx:A   (TRP673) to   (HIS750)  SOLUTION STRUCTURE OF VAV2 SH2 DOMAIN  |   SIGNALING PROTEIN 
2lqn:A    (TRP14) to    (LYS89)  SOLUTION STRUCTURE OF CRKL  |   SH2, SH3, V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG (AVIAN)-LIKE, SIGNALING PROTEIN 
1x27:A   (TRP127) to   (ALA212)  CRYSTAL STRUCTURE OF LCK SH2-SH3 WITH SH2 BINDING SITE OF P130CAS  |   LCK-CAS COMPLEX, LCK PHOSPHO-PEPTIDE COMPLEX, HIGH AFFINITY LCK-CAS COMPLEX, SIGNALING PROTEIN 
1x27:B   (TRP127) to   (ALA212)  CRYSTAL STRUCTURE OF LCK SH2-SH3 WITH SH2 BINDING SITE OF P130CAS  |   LCK-CAS COMPLEX, LCK PHOSPHO-PEPTIDE COMPLEX, HIGH AFFINITY LCK-CAS COMPLEX, SIGNALING PROTEIN 
1x27:C   (TRP127) to   (ALA212)  CRYSTAL STRUCTURE OF LCK SH2-SH3 WITH SH2 BINDING SITE OF P130CAS  |   LCK-CAS COMPLEX, LCK PHOSPHO-PEPTIDE COMPLEX, HIGH AFFINITY LCK-CAS COMPLEX, SIGNALING PROTEIN 
1x27:E   (TRP127) to   (ALA212)  CRYSTAL STRUCTURE OF LCK SH2-SH3 WITH SH2 BINDING SITE OF P130CAS  |   LCK-CAS COMPLEX, LCK PHOSPHO-PEPTIDE COMPLEX, HIGH AFFINITY LCK-CAS COMPLEX, SIGNALING PROTEIN 
1x27:F   (TRP127) to   (ALA212)  CRYSTAL STRUCTURE OF LCK SH2-SH3 WITH SH2 BINDING SITE OF P130CAS  |   LCK-CAS COMPLEX, LCK PHOSPHO-PEPTIDE COMPLEX, HIGH AFFINITY LCK-CAS COMPLEX, SIGNALING PROTEIN 
2yu7:A     (TRP8) to    (THR95)  SOLUTION STRUCTURE OF THE SHP-1 C-TERMINAL SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM NKG2A  |   SH2 DOMAIN, PROTEIN-PEPTIDE COMPLEX, PHOSPHORYLATED PEPTIDE RECOGNITION, PHOSPHOTYROSINE BINDING DOMAIN, SIGNAL TRANSDUCTION, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, SIGNALING PROTEIN 
1lcj:A   (TRP127) to   (ALA212)  SH2 (SRC HOMOLOGY-2) DOMAIN OF HUMAN P56-LCK TYROSINE KINASE COMPLEXED WITH THE 11 RESIDUE PHOSPHOTYROSYL PEPTIDE EPQPYEEIPIYL  |   COMPLEX (KINASE/PEPTIDE) 
1lck:A   (TRP127) to   (ALA212)  SH3-SH2 DOMAIN FRAGMENT OF HUMAN P56-LCK TYROSINE KINASE COMPLEXED WITH THE 10 RESIDUE SYNTHETIC PHOSPHOTYROSYL PEPTIDE TEGQPYQPQPA  |   COMPLEX (KINASE/PEPTIDE) 
1lkk:A   (TRP127) to   (ALA212)  HUMAN P56-LCK TYROSINE KINASE SH2 DOMAIN IN COMPLEX WITH THE PHOSPHOTYROSYL PEPTIDE AC-PTYR-GLU-GLU-ILE (PYEEI PEPTIDE)  |   COMPLEX (TYROSINE KINASE/PEPTIDE) 
4ohh:A     (TRP6) to    (HIS84)  LEOPARD SYNDROME-ASSOCIATED SHP2/Q506P MUTANT  |   SH2 DOMAIN, PHOSPHATASE DOMAIN, HYDROLASE 
4ohh:A   (TRP112) to   (ASN200)  LEOPARD SYNDROME-ASSOCIATED SHP2/Q506P MUTANT  |   SH2 DOMAIN, PHOSPHATASE DOMAIN, HYDROLASE 
1m61:A    (PHE10) to    (ASP90)  CRYSTAL STRUCTURE OF THE APO SH2 DOMAINS OF ZAP-70  |   APO FORM, TRANSFERASE 
1m61:A   (TRP163) to   (LYS240)  CRYSTAL STRUCTURE OF THE APO SH2 DOMAINS OF ZAP-70  |   APO FORM, TRANSFERASE 
5d0j:B   (TRP431) to   (GLN513)  GRB7 SH2 WITH INHIBITOR PEPTIDE  |   INHIBITOR, SH2, SIGNALING PROTEIN 
5d0j:D   (TRP431) to   (GLN513)  GRB7 SH2 WITH INHIBITOR PEPTIDE  |   INHIBITOR, SH2, SIGNALING PROTEIN 
1zfp:E    (TRP60) to   (ARG136)  GROWTH FACTOR RECEPTOR BINDING PROTEIN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PENTAPEPTIDE  |   SIGNAL TRANSDUCTION, SH2 DOMAIN, PHOSPHOTYROSYL PEPTIDE, COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 
5eel:F   (TRP431) to   (GLN513)  GRB7 SH2 WITH BICYCLIC PEPTIDE INHIBITOR  |   SH2, INHIBITOR, BICYCLIC, SIGNALING PROTEIN-PEPTIDE COMPLEX 
3m7f:A   (TRP435) to   (LEU518)  CRYSTAL STRUCTURE OF THE NEDD4 C2/GRB10 SH2 COMPLEX  |   NEDD4, C2 DOMAIN, GRB10, SH2 DOMAIN, PHOSPHOPROTEIN, LIGASE, UBL CONJUGATION PATHWAY, SIGNALING PROTEIN-LIGASE COMPLEX 
5ehp:A   (TRP112) to   (PRO201)  NON-RECEPTOR PROTEIN TYROSINE PHOSPHATASE SHP2 IN COMPLEX WITH ALLOSTERIC INHIBITOR SHP836  |   PHOSPHATASE PTP INHIBITOR PTPN11 ALLOSTERIC, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5ehp:B   (TRP112) to   (PRO201)  NON-RECEPTOR PROTEIN TYROSINE PHOSPHATASE SHP2 IN COMPLEX WITH ALLOSTERIC INHIBITOR SHP836  |   PHOSPHATASE PTP INHIBITOR PTPN11 ALLOSTERIC, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3mxc:A    (TRP60) to   (ARG136)  STRUCTURES OF GRB2-SH2 DOMAIN AND AICD PEPTIDE COMPLEXES REVEAL A CONFORMATIONAL SWITCH AND THEIR FUNCTIONAL IMPLICATIONS.  |   PROTEIN-PEPTIDE COMPLEX, AICD, GRB2-SH2, PROTEIN BINDING, ALZHEIMER'S DISEASE, APP 
3n7y:A    (TRP60) to   (ARG136)  CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A 20-MEMBERED MACROCYCLIC LIGAND HAVING THE SEQUENCE PYVNV  |   LIGAND PREORGANIZATION, MACROCYCLES, MACROCYCLIC LIGANDS, GOLGI APPARATUS, HOST-VIRUS INTERACTION, PHOSPHOPROTEIN, PROTEIN BINDING- PEPTIDE COMPLEX 
3n7y:B    (TRP60) to   (HIS135)  CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A 20-MEMBERED MACROCYCLIC LIGAND HAVING THE SEQUENCE PYVNV  |   LIGAND PREORGANIZATION, MACROCYCLES, MACROCYCLIC LIGANDS, GOLGI APPARATUS, HOST-VIRUS INTERACTION, PHOSPHOPROTEIN, PROTEIN BINDING- PEPTIDE COMPLEX 
3n84:B    (TRP60) to   (ARG136)  CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A 23-MEMBERED MACROCYCLIC LIGAND HAVING THE SEQUENCE PYVNVP  |   LIGAND PREORGANIZATION, MACROCYCLES, MACROCYCLIC LIGANDS, GOLGI APPARATUS, HOST-VIRUS INTERACTION, PHOSPHOPROTEIN, PROTEIN BINDING- PEPTIDE COMPLEX 
3n84:C    (TRP60) to   (ARG136)  CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A 23-MEMBERED MACROCYCLIC LIGAND HAVING THE SEQUENCE PYVNVP  |   LIGAND PREORGANIZATION, MACROCYCLES, MACROCYCLIC LIGANDS, GOLGI APPARATUS, HOST-VIRUS INTERACTION, PHOSPHOPROTEIN, PROTEIN BINDING- PEPTIDE COMPLEX 
3n84:D    (TRP60) to   (ARG136)  CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A 23-MEMBERED MACROCYCLIC LIGAND HAVING THE SEQUENCE PYVNVP  |   LIGAND PREORGANIZATION, MACROCYCLES, MACROCYCLIC LIGANDS, GOLGI APPARATUS, HOST-VIRUS INTERACTION, PHOSPHOPROTEIN, PROTEIN BINDING- PEPTIDE COMPLEX 
4tzi:A   (TRP129) to   (GLN214)  STRUCTURE OF UNLIGANDED LYN SH2 DOMAIN  |   SH2 DOMAIN, TRANSFERASE 
4tzi:B   (TRP129) to   (GLN214)  STRUCTURE OF UNLIGANDED LYN SH2 DOMAIN  |   SH2 DOMAIN, TRANSFERASE 
4d8k:A   (TRP127) to   (ALA212)  CRYSTAL STRUCTURE OF A SH3-SH2 DOMAINS OF A LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE KINASE (LCK) FROM HOMO SAPIENS AT 2.36 A RESOLUTION  |   PROTEIN KINASES, SH2 DOMAIN, SH3 DOMAIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, PARTNERSHIP FOR T-CELL BIOLOGY, TCELL, TRANSFERASE 
4u1p:A    (TRP23) to   (ARG108)  HUMAN FYN-SH2 DOMAIN IN COMPLEX WITH A SYNTHETIC HIGH-AFFINITY PHOSPHO-PEPTIDE  |   SH2 DOMAIN, PROTEIN PEPTIDE INTERACTIONS, ALLOSTERY, TYROSINE PHOSPHORYLATION, FYN, KINASE, TRANSFERASE 
3ov1:A    (TRP60) to   (ARG136)  CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A PYXN- DERIVED TRIPEPTIDE  |   GRB2 SH2 DOMAIN, PHOSPHOTYROSINE BINDING, SIGNALING PROTEIN, SIGNALING PROTEIN-ANTAGONIST COMPLEX 
5i6v:A   (TRP112) to   (ASN200)  STRUCTURE OF F285S, A CANCER-ASSOCIATED MUTATION OF THE ONCOGENIC PHOSPHATASE SHP2  |   SHP2, CANCER-ASSOCIATED MUTATION, INHIBITORS, HYDROLASE 
5i6v:B     (TRP6) to    (HIS84)  STRUCTURE OF F285S, A CANCER-ASSOCIATED MUTATION OF THE ONCOGENIC PHOSPHATASE SHP2  |   SHP2, CANCER-ASSOCIATED MUTATION, INHIBITORS, HYDROLASE 
5ibm:A     (TRP6) to    (HIS84)  STRUCTURE OF S502P, A CANCER-ASSOCIATED MUTATION OF THE ONCOGENIC PHOSPHATASE SHP2  |   TYROSINE PHOSPHATASE SHP2 S502P, TYROSINE-PROTEIN PHOSPHATASE NON- RECEPTOR TYPE 11, HYDROLASE 
5ibm:A   (TRP112) to   (PRO201)  STRUCTURE OF S502P, A CANCER-ASSOCIATED MUTATION OF THE ONCOGENIC PHOSPHATASE SHP2  |   TYROSINE PHOSPHATASE SHP2 S502P, TYROSINE-PROTEIN PHOSPHATASE NON- RECEPTOR TYPE 11, HYDROLASE 
5ibm:B   (TRP112) to   (ASN200)  STRUCTURE OF S502P, A CANCER-ASSOCIATED MUTATION OF THE ONCOGENIC PHOSPHATASE SHP2  |   TYROSINE PHOSPHATASE SHP2 S502P, TYROSINE-PROTEIN PHOSPHATASE NON- RECEPTOR TYPE 11, HYDROLASE 
5ibs:A   (TRP112) to   (ASN200)  STRUCTURE OF E76Q, A CANCER-ASSOCIATED MUTATION OF THE ONCOGENIC PHOSPHATASE SHP2  |   TYROSINE PHOSPHATASE SHP2, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11, HYDROLASE 
5ibs:B     (TRP6) to    (HIS84)  STRUCTURE OF E76Q, A CANCER-ASSOCIATED MUTATION OF THE ONCOGENIC PHOSPHATASE SHP2  |   TYROSINE PHOSPHATASE SHP2, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11, HYDROLASE 
5ibs:B   (TRP112) to   (ASN200)  STRUCTURE OF E76Q, A CANCER-ASSOCIATED MUTATION OF THE ONCOGENIC PHOSPHATASE SHP2  |   TYROSINE PHOSPHATASE SHP2, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11, HYDROLASE 
4ey0:A   (TRP550) to   (VAL642)  STRUCTURE OF TANDEM SH2 DOMAINS FROM PLCGAMMA1  |   SH2 DOMAIN, PLCGAMMA SPECIFIC ARRAY, INTERACTION DOMAIN, FIBROBLAST GROWTH FACTOR RECEPTOR 1, HYDROLASE 
4ey0:B   (TRP550) to   (VAL642)  STRUCTURE OF TANDEM SH2 DOMAINS FROM PLCGAMMA1  |   SH2 DOMAIN, PLCGAMMA SPECIFIC ARRAY, INTERACTION DOMAIN, FIBROBLAST GROWTH FACTOR RECEPTOR 1, HYDROLASE 
4ey0:C   (TRP550) to   (VAL642)  STRUCTURE OF TANDEM SH2 DOMAINS FROM PLCGAMMA1  |   SH2 DOMAIN, PLCGAMMA SPECIFIC ARRAY, INTERACTION DOMAIN, FIBROBLAST GROWTH FACTOR RECEPTOR 1, HYDROLASE 
4ey0:D   (TRP550) to   (VAL642)  STRUCTURE OF TANDEM SH2 DOMAINS FROM PLCGAMMA1  |   SH2 DOMAIN, PLCGAMMA SPECIFIC ARRAY, INTERACTION DOMAIN, FIBROBLAST GROWTH FACTOR RECEPTOR 1, HYDROLASE 
2aug:B   (TRP439) to   (LEU522)  CRYSTAL STRUCTURE OF THE GRB14 SH2 DOMAIN  |   PHOSPHORYLATION, SH2 DOMAIN, SIGNALING PROTEIN 
1nzl:B   (TRP254) to   (HIS339)  CRYSTAL STRUCTURE OF SRC SH2 DOMAIN BOUND TO DOUBLY PHOSPHORYLATED PEPTIDE PQPYEPYIPI  |   SH2 DOMAIN, PHOSPHOTYROSINE, TRANSFERASE 
1o4f:A     (TRP7) to    (ALA93)  CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU79073.  |   SH2 DOMAIN FRAGMENT APPROACH, SIGNALING PROTEIN 
1bm2:A    (TRP60) to   (ARG136)  GRB2-SH2 DOMAIN IN COMPLEX WITH CYCLO-[N-ALPHA-ACETYL-L-THI ALYSYL-O-PHOSPHOTYROSYL-VALYL-ASPARAGYL-VALYL-PROLYL] (PKF273-791)  |   SH2 DOMAIN, SIGNAL TRANSDUCTION, ADAPTOR PROTEIN, RAS PATHWAY, CYCLIC PEPTIDE, HORMONE/GROWTH FACTOR COMPLEX 
2ptk:A   (TRP148) to   (HIS233)  CHICKEN SRC TYROSINE KINASE  |   TYROSINE-PROTEIN KINASE, SRC, SH2, SH3 
2dly:A    (TRP18) to    (THR98)  SOLUTION STRUCTURE OF THE SH2 DOMAIN OF MURINE FYN-RELATED KINASE  |   BRK FAMILY KINASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE 
1f1w:A   (TRP148) to   (HIS233)  SRC SH2 THREF1TRP MUTANT COMPLEXED WITH THE PHOSPHOPEPTIDE S(PTR)VNVQN  |   SRC, SH2 DOMAIN, PHOSPHOPEPTIDE, SPECIFICITY SWITCH, TRANSFERASE 
3hck:A     (TRP6) to    (GLY91)  NMR ENSEMBLE OF THE UNCOMPLEXED HUMAN HCK SH2 DOMAIN, 20 STRUCTURES  |   HCK, SH2, TYROSINE KINASE, SIGNAL TRANSDUCTION, TRANSFERASE 
2eo3:A    (TRP21) to    (LYS96)  SOLUTION STRUCTURE OF THE SH2 DOMAIN FROM HUMAN CRK-LIKE PROTEIN  |   PHOSPHORYLATION, REPEAT, SH2 DOMAIN, SH3 DOMAIN, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, SIGNALING PROTEIN 
2eob:A    (TRP21) to    (GLU96)  SOLUTION STRUCTURE OF THE SECOND SH2 DOMAIN FROM RAT PLC GAMMA-2  |   SH2, PHOSPHOINOSITIDE PHOSPHOLIPASE C, PLC-GAMMA-2, PHOSPHOLIPASE C-GAMMA-2, PLC-IV, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, HYDROLASE 
1g83:A   (TRP149) to   (ARG234)  CRYSTAL STRUCTURE OF FYN SH3-SH2  |   BETA BARREL, ANTIPARALLEL BETA SHEET, ALPHA HELIX, 3-10 HELIX, TRANSFERASE 
1is0:A   (TRP148) to   (HIS233)  CRYSTAL STRUCTURE OF A COMPLEX OF THE SRC SH2 DOMAIN WITH CONFORMATIONALLY CONSTRAINED PEPTIDE INHIBITOR  |   CONFORMATIONALY CONSTRAINED INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
1is0:B   (TRP148) to   (HIS233)  CRYSTAL STRUCTURE OF A COMPLEX OF THE SRC SH2 DOMAIN WITH CONFORMATIONALLY CONSTRAINED PEPTIDE INHIBITOR  |   CONFORMATIONALY CONSTRAINED INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
1jyq:B    (TRP60) to   (ARG136)  XRAY STRUCTURE OF GRB2 SH2 DOMAIN COMPLEXED WITH A HIGHLY AFFINE PHOSPHO PEPTIDE  |   RECEPTOR BINDING, REGULATORY, SIGNALING PROTEIN-SIGNALING PROTEIN INHIBITOR, SIGNALING PROTEIN-PEPTIDE INHIBITOR COMPLEX 
2k7a:B   (TRP239) to   (GLN323)  ENSEMBLE STRUCTURES OF THE BINARY COMPLEX BETWEEN THE SH3 AND SH2 DOMAIN OF INTERLEUKIN-2 TYROSINE KINASE.  |   SH3, SH2, NOVEL, CIS, ATP-BINDING, CELL MEMBRANE, KINASE, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SH2 DOMAIN, SH3 DOMAIN, TRANSFERASE, TYROSINE-PROTEIN KINASE, ZINC, ZINC-FINGER 
1x0n:A    (TRP60) to   (THR138)  NMR STRUCTURE OF GROWTH FACTOR RECEPTOR BINDING PROTEIN SH2 DOMAIN COMPLEXED WITH THE INHIBITOR  |   PEPTIDE BINDING PROTEIN 
5ehr:A   (TRP112) to   (ASN200)  NON-RECEPTOR PROTEIN TYROSINE PHOSPHATASE SHP2 IN COMPLEX WITH ALLOSTERIC INHIBITOR SHP099  |   PHOSPHATASE PTP INHIBITOR PTPN11 ALLOSTERIC, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5ehr:B   (TRP112) to   (PRO201)  NON-RECEPTOR PROTEIN TYROSINE PHOSPHATASE SHP2 IN COMPLEX WITH ALLOSTERIC INHIBITOR SHP099  |   PHOSPHATASE PTP INHIBITOR PTPN11 ALLOSTERIC, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4dgp:A   (TRP112) to   (LYS199)  THE WILD-TYPE SRC HOMOLOGY 2 (SH2)-DOMAIN CONTAINING PROTEIN TYROSINE PHOSPHATASE-2 (SHP2)  |   HYDROLASE