2aid:B    (LYS45) to    (GLY94)  STRUCTURE OF A NON-PEPTIDE INHIBITOR COMPLEXED WITH HIV-1 PROTEASE: DEVELOPING A CYCLE OF STRUCTURE-BASED DRUG DESIGN  |   ASPARTYL PROTEASE, HIV, NON-PEPTIDE INHIBITOR, DRUG DESIGN 
1a30:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE COMPLEXED WITH A TRIPEPTIDE INHIBITOR  |   ASPARTIC PROTEASE, HIV PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1a8g:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH SDZ283-910  |   ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1a8g:B    (LYS45) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH SDZ283-910  |   ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1a8k:B    (LYS45) to    (GLY94)  CRYSTALLOGRAPHIC ANALYSIS OF HUMAN IMMUNODEFICIENCY VIRUS 1 PROTEASE WITH AN ANALOG OF THE CONSERVED CA-P2 SUBSTRATE: INTERACTIONS WITH FREQUENTLY OCCURRING GLUTAMIC ACID RESIDUE AT P2' POSITION OF SUBSTRATES  |   HUMAN IMMUNODEFICIENCY VIRUS PROTEASE, PROTON-MEDIATED INTERACTION, VIRAL MATURATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1a8k:D    (GLY52) to    (GLY94)  CRYSTALLOGRAPHIC ANALYSIS OF HUMAN IMMUNODEFICIENCY VIRUS 1 PROTEASE WITH AN ANALOG OF THE CONSERVED CA-P2 SUBSTRATE: INTERACTIONS WITH FREQUENTLY OCCURRING GLUTAMIC ACID RESIDUE AT P2' POSITION OF SUBSTRATES  |   HUMAN IMMUNODEFICIENCY VIRUS PROTEASE, PROTON-MEDIATED INTERACTION, VIRAL MATURATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1a94:B    (LYS45) to    (GLY94)  STRUCTURAL BASIS FOR SPECIFICITY OF RETROVIRAL PROTEASES  |   HUMAN IMMUNODEFICIENCY VIRUS PROTEASE, ROUS SARCOMA VIRUS PROTEASE, PROTEIN-MEDIATED INTERACTION, VIRAL MATURATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2aoe:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A SUBSTRATE ANALOG CA-P2  |   HIV-1 PROTEASE, SUBSTRATE ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2aog:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A SUBSTRATE ANALOG P2-NC  |   HIV-1 PROTEASE, MUTANT, DIMER, SUBSTRATE ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2aoi:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE WITH A SUBSTRATE ANALOG P1-P6  |   HIV-1 PROTEASE, MUTANT, DIMER, SUBSTRATE ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1a9m:B    (GLY52) to    (ILE93)  G48H MUTANT OF HIV-1 PROTEASE IN COMPLEX WITH A PEPTIDIC INHIBITOR U-89360E  |   ASPARTYL PROTEASE, DRUG RESISTANT, MUTATION 
2aoj:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE WITH A SUBSTRATE ANALOG P6-PR  |   HIV-1 PROTEASE, MUTANT, DIMER, SUBSTRATE ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2aqu:A    (LYS45) to    (GLY94)  STRUCTURE OF HIV-1 PROTEASE BOUND TO ATAZANAVIR  |   AIDS, ASPARTYL PROTEASE, HYDROLASE,, HYDROLASE 
2aqu:B    (LYS45) to    (GLY94)  STRUCTURE OF HIV-1 PROTEASE BOUND TO ATAZANAVIR  |   AIDS, ASPARTYL PROTEASE, HYDROLASE,, HYDROLASE 
1aaq:A    (GLY40) to    (GLY94)  HYDROXYETHYLENE ISOSTERE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE: STRUCTURE-ACTIVITY ANALYSIS USING ENZYME KINETICS, X-RAY CRYSTALLOGRAPHY, AND INFECTED T-CELL ASSAYS  |   ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1nh0:B    (GLY52) to    (GLY94)  1.03 A STRUCTURE OF HIV-1 PROTEASE: INHIBITOR BINDING INSIDE AND OUTSIDE THE ACTIVE SITE  |   ASPARTYL PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS, INHIBITOR DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4gye:A    (LYS45) to    (GLY94)  MDR 769 HIV-1 PROTEASE IN COMPLEX WITH REDUCED P1F  |   MULTI-DRUG RESISTANCE, PROTEASE INHIBITOR, DRUG RESISTANCE, SUBSTRATE PEPTIDE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4gye:B    (LYS45) to    (GLY94)  MDR 769 HIV-1 PROTEASE IN COMPLEX WITH REDUCED P1F  |   MULTI-DRUG RESISTANCE, PROTEASE INHIBITOR, DRUG RESISTANCE, SUBSTRATE PEPTIDE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2avm:B    (GLY52) to    (GLY94)  KINETICS, STABILITY, AND STRUCTURAL CHANGES IN HIGH RESOLUTION CRYSTAL STRUCTURES OF HIV-1 PROTEASE WITH DRUG RESISTANT MUTATIONS L24I, I50V, AND G73S  |   HIV-1 PROTEASE, DRUG RESISTANCE, SUBSTRATE ANALOG, NON-ACTIVE SITE MUTANTS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2avo:A    (GLY52) to    (GLY94)  KINETICS, STABILITY, AND STRUCTURAL CHANGES IN HIGH RESOLUTION CRYSTAL STRUCTURES OF HIV-1 PROTEASE WITH DRUG RESISTANT MUTATIONS L24I, I50V, AND G73S  |   DRUG RESISTANCE; HIV-1 PROTEASE,INDINAVIR, SUBSTRATE ANALOG,NON- ACTIVE SITE MUTANTS., HYDROLASE 
2avo:B    (LYS45) to    (GLY94)  KINETICS, STABILITY, AND STRUCTURAL CHANGES IN HIGH RESOLUTION CRYSTAL STRUCTURES OF HIV-1 PROTEASE WITH DRUG RESISTANT MUTATIONS L24I, I50V, AND G73S  |   DRUG RESISTANCE; HIV-1 PROTEASE,INDINAVIR, SUBSTRATE ANALOG,NON- ACTIVE SITE MUTANTS., HYDROLASE 
2avq:A    (LYS45) to    (GLY94)  KINETICS, STABILITY, AND STRUCTURAL CHANGES IN HIGH RESOLUTION CRYSTAL STRUCTURES OF HIV-1 PROTEASE WITH DRUG RESISTANT MUTATIONS L24I, I50V, AND G73S  |   HIV-1 PROTEASE, DRUG RESISTANT, SUBSTRATE ANALOG, NON-ACTIVE SITE MUTANTS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2avv:D    (LYS45) to    (GLY94)  KINETICS, STABILITY, AND STRUCTURAL CHANGES IN HIGH RESOLUTION CRYSTAL STRUCTURES OF HIV-1 PROTEASE WITH DRUG RESISTANT MUTATIONS L24I, I50V, AND G73S  |   DRUG RESISTANCE, HIV-1 PROTEASE,INDINAVIR, SUBSTRATE ANALOG, NON-ACTIVE SITE MUTANTS., HYDROLASE 
4gzf:B    (LYS45) to    (GLY94)  MULTI-DRUG RESISTANT HIV-1 PROTEASE 769 VARIANT WITH REDUCED LRF PEPTIDE  |   MULTI-DRUG RESISTANCE, PROTEASE INHIBITOR, DRUG RESISTANCE, SUBSTRATE PEPTIDES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1aid:A    (LYS45) to    (GLY94)  STRUCTURE OF A NON-PEPTIDE INHIBITOR COMPLEXED WITH HIV-1 PROTEASE: DEVELOPING A CYCLE OF STRUCTURE-BASED DRUG DESIGN  |   HYDROLASE, PROTEASE, HIV, NON-PEPTIDE INHIBITOR, DRUG DESIGN 
2az9:A    (GLY40) to    (GLY94)  HIV-1 PROTEASE NL4-3 1X MUTANT  |   HIV, PROTEASE, INHIBITOR, TL-3, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2azb:A    (GLY40) to    (GLY94)  HIV-1 PROTEASE NL4-3 3X MUTANT IN COMPLEX WITH INHIBITOR, TL-3  |   HIV-1, PROTEASE, INHIBITOR, TL-3, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1ajx:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH THE CYCLIC UREA INHIBITOR AHA001  |   PROTEASE, ASPARTYL PROTEASE, NON-PEPTIDE INHIBITOR, DRUG DESIGN, HIV-1 
1npv:B   (PRO244) to   (GLY294)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH LDC271  |   PROTEASE, HYDROLASE 
3ekp:C    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF THE INHIBITOR AMPRENAVIR (APV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10I/G48V/I54V/V64I/V82A)REFER: FLAP+ IN CITATION  |   HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, AMPRENAVIR, AIDS, HYDROLASE 
3ekp:D    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF THE INHIBITOR AMPRENAVIR (APV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10I/G48V/I54V/V64I/V82A)REFER: FLAP+ IN CITATION  |   HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, AMPRENAVIR, AIDS, HYDROLASE 
3ekq:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF INHIBITOR SAQUINAVIR (SQV) IN COMPLEX WITH MULTI- DRUG RESISTANT HIV-1 PROTEASE (L63P/V82T/I84V) (REFERRED TO AS ACT IN PAPER)  |   PROTEASE INHIBITOR, DRUG RESISTANCE, ENTROPY ENTHALPY COMPENSATION, AIDS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASE 
3ekt:A    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF THE INHIBITOR DARUNAVIR (DRV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10F/G48V/I54V/V64I/V82A) (REFER: FLAP+ IN CITATION.)  |   HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, DARUNAVIR, AIDS, HYDROLASE 
3ekt:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF THE INHIBITOR DARUNAVIR (DRV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10F/G48V/I54V/V64I/V82A) (REFER: FLAP+ IN CITATION.)  |   HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, DARUNAVIR, AIDS, HYDROLASE 
3ekv:B    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF THE WILD TYPE HIV-1 PROTEASE WITH THE INHIBITOR, AMPRENAVIR  |   PROTEASE INHIBITOR, DRUG RESISTANCE, AMPRENAVIR, HIV PROTEASE, AIDS, PROTEASE, HYDROLASE 
3ekw:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF THE INHIBITOR ATAZANAVIR (ATV) IN COMPLEX WITH A MULTI-DRUG RESISTANCE HIV-1 PROTEASE VARIANT (L10I/G48V/I54V/V64I/V82A) REFER: FLAP+ IN CITATION.  |   HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, ATAZANAVIR, AIDS, HYDROLASE 
3eky:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV PROTEASE IN COMPLEX WITH THE INHIBITOR, ATAZANAVIR  |   HIV PROTEASE, PROTEASE INHIBITORS, DRUG RESISTANCE, ATAZANAVIR, AIDS, HYDROLASE, PROTEASE 
3el0:A    (LYS41) to    (GLY94)  CRYSTAL STRUCTURE OF THE INHIBITOR NELFINAVIR (NFV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10I/G48V/I54V/V64I/V82A) (REFER: FLAP+ IN CITATION)  |   HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, NELFINAVIR, AIDS, HYDROLASE 
3el0:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF THE INHIBITOR NELFINAVIR (NFV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10I/G48V/I54V/V64I/V82A) (REFER: FLAP+ IN CITATION)  |   HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, NELFINAVIR, AIDS, HYDROLASE 
3el1:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV PROTEASE IN COMPLEX WITH THE INHIBITOR, ATAZANAVIR  |   HIV PROTEASE, PROTEASE INHIBITORS, DRUG RESISTANCE, ATAZANAVIR, AIDS, HYDROLASE, PROTEASE 
3el5:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF NELFINAVIR (NFV) COMPLEXED WITH A MULTIDRUG VARIANT (ACT) (V82T/I84V) OF HIV-1 PROTEASE  |   PROTEASE INHIBITOR, DRUG RESISTANCE, NELFINAVIR, HIV-1 PROTEASE, ENTROPY-ENTHALPY COMPENSATION, HYDROLASE 
3el5:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF NELFINAVIR (NFV) COMPLEXED WITH A MULTIDRUG VARIANT (ACT) (V82T/I84V) OF HIV-1 PROTEASE  |   PROTEASE INHIBITOR, DRUG RESISTANCE, NELFINAVIR, HIV-1 PROTEASE, ENTROPY-ENTHALPY COMPENSATION, HYDROLASE 
3el9:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF ATAZANAVIR (ATV) IN COMPLEX WITH A MULTIDRUG HIV- 1 PROTEASE (V82T/I84V)  |   DRUG RESISTANCE, ENTROPY ENTHALPY COMPENSATION, HIV PROTEASE, ATAZANAVIR, AIDS, HYDROLASE 
3el9:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF ATAZANAVIR (ATV) IN COMPLEX WITH A MULTIDRUG HIV- 1 PROTEASE (V82T/I84V)  |   DRUG RESISTANCE, ENTROPY ENTHALPY COMPENSATION, HIV PROTEASE, ATAZANAVIR, AIDS, HYDROLASE 
3em3:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF AMPRENAVIR (APV) IN COMPLEX WITH A DRUG RESISTANT HIV-1 PROTEASE VARIANT (I50L/A71V).  |   PROTEASE INHIBITOR, HYPER SUSCEPTIBILITY, DRUG RESISTANCE, HIV, AMPRENAVIR, AIDS, HYDROLASE, PROTEASE 
3em4:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF ATAZANAVIR (ATV) IN COMPLEX WITH I50L/A71V DRUG- RESISTANT HIV-1 PROTEASE  |   DRUG RESISTANCE, HYPERSUSCEPTIBILITY, PROTEASE INHIBITOR, HIV, ATAZANAVIR, AIDS, HYDROLASE, PROTEASE 
3em4:U    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF ATAZANAVIR (ATV) IN COMPLEX WITH I50L/A71V DRUG- RESISTANT HIV-1 PROTEASE  |   DRUG RESISTANCE, HYPERSUSCEPTIBILITY, PROTEASE INHIBITOR, HIV, ATAZANAVIR, AIDS, HYDROLASE, PROTEASE 
3em6:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF I50L/A71V MUTANT OF HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR DARUNAVIR  |   PROTEASE INHIBITOR, HYPER SUSCEPTIBILITY, DRUG RESISTANCE, HIV, DARUNAVIR, AIDS, HYDROLASE, PROTEASE 
1axa:B    (LYS45) to    (GLY94)  ACTIVE-SITE MOBILITY IN HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE AS DEMONSTRATED BY CRYSTAL STRUCTURE OF A28S MUTANT  |   HIV PROTEASE, MUTANT, X-RAY, ASPARTIC PROTEASE, HYDROLASE, ACID PROTEINASE, ASPARTYL PROTEASE 
2b7z:B    (GLY40) to    (ILE93)  STRUCTURE OF HIV-1 PROTEASE MUTANT BOUND TO INDINAVIR  |   HIV-1, PROTEASE, INDINAVIR, DRUG RESISTANCE, ACTIVE SITE MUTATIONS, NON-ACTIVE SITE MUTATIONS,VIRAL PROTEIN, VIRAL PROTEIN 
2bb9:A    (GLY40) to    (GLY94)  STRUCTURE OF HIV1 PROTEASE AND AKC4P_133A COMPLEX.  |   PROTEASE, HYDROLASE 
2bb9:B   (PRO244) to   (GLY294)  STRUCTURE OF HIV1 PROTEASE AND AKC4P_133A COMPLEX.  |   PROTEASE, HYDROLASE 
2bbb:B   (PRO244) to   (GLY294)  STRUCTURE OF HIV1 PROTEASE AND HH1_173_3A COMPLEX.  |   PROTEASE, HYDROLASE 
2p3b:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF THE SUBTYPE B WILD TYPE HIV PROTEASE COMPLEXED WITH TL-3 INHIBITOR  |   WILD TYPE SUBTYPE B HIV PROTEASE, TL-3 INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4hdb:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANTS D30N COMPLEXED WITH INHIBITOR GRL-0519  |   ASPARTIC ACID PROTEASE, DRUG RESISTANCE, HIV-1 PROTEASE INHIBITOR GRL-0519, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4hdf:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANTS V82A COMPLEXED WITH INHIBITOR GRL-0519  |   ASPARTIC ACID PROTEASE, DRUG RESISTANCE, HIV-1 PROTEASE INHIBITOR GRL-0519, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4hdp:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANTS I50V COMPLEXED WITH INHIBITOR GRL-0519  |   ASPARTIC ACID PROTEASE, DRUG RESISTANCE, HIV-1 PROTEASE INHIBITOR GRL-0519, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4hdp:A    (PRO44) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANTS I50V COMPLEXED WITH INHIBITOR GRL-0519  |   ASPARTIC ACID PROTEASE, DRUG RESISTANCE, HIV-1 PROTEASE INHIBITOR GRL-0519, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4he9:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANTS I54M COMPLEXED WITH INHIBITOR GRL-0519  |   ASPARTIC ACID PROTEASE, DRUG RESISTANCE, HIV-1 PROTEASE INHIBITOR GRL-0519, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4he9:B    (PRO44) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANTS I54M COMPLEXED WITH INHIBITOR GRL-0519  |   ASPARTIC ACID PROTEASE, DRUG RESISTANCE, HIV-1 PROTEASE INHIBITOR GRL-0519, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4heg:A    (PRO44) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANTS R8Q COMPLEXED WITH INHIBITOR GRL-0519  |   ASPARTIC ACID PROTEASE, DRUG RESISTANCE, HIV-1 PROTEASE INHIBITOR GRL-0519, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1b6j:B   (GLY152) to   (GLY194)  HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 1  |   COMPLEX (ACID PROTEINASE-PEPTIDE), HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1bdl:A    (GLY52) to    (GLY94)  HIV-1 (2:31-37) PROTEASE COMPLEXED WITH INHIBITOR SB203386  |   HYDROLASE, AIDS, POLYPROTEIN, ASPARTYL PROTEASE, ACID PROTEASE, HYDROXYETHYLENE ISOSTERE INHIBITOR, SUBSTRATE ANALOGUE INHIBITOR 
1bdl:B    (PRO44) to    (GLY94)  HIV-1 (2:31-37) PROTEASE COMPLEXED WITH INHIBITOR SB203386  |   HYDROLASE, AIDS, POLYPROTEIN, ASPARTYL PROTEASE, ACID PROTEASE, HYDROXYETHYLENE ISOSTERE INHIBITOR, SUBSTRATE ANALOGUE INHIBITOR 
3s43:A    (GLY40) to    (GLY94)  HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH ANTIVIRAL DRUG AMPRENAVIR  |   AMPRENAVIR, HIV/AIDS, DRUG RESISTANCE, ASPARTIC PROTEASE, MOLECULAR RECOGNITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4hla:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH DARUNAVIR  |   DARUNAVIR, PROTEASE, HYDROLASE, GAG, GAG-POL, TMC114, UIC-94017, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4hla:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH DARUNAVIR  |   DARUNAVIR, PROTEASE, HYDROLASE, GAG, GAG-POL, TMC114, UIC-94017, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3s54:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH ANTIVIRAL DRUG DARUNAVIR IN SPACE GROUP P21212  |   DARUNAVIR,HIV/AIDS, DRUG RESISTANCE, ASPARTIC PROTEASE, MOLECULAR RECOGNITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3s56:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH ANTIVIRAL DRUG SAQUINAVIR  |   SAQUINAVIR,HIV/AIDS, DRUG RESISTANCE, ASPARTIC PROTEASE, MOLECULAR RECOGNITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3s56:B    (LYS45) to    (GLY94)  HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH ANTIVIRAL DRUG SAQUINAVIR  |   SAQUINAVIR,HIV/AIDS, DRUG RESISTANCE, ASPARTIC PROTEASE, MOLECULAR RECOGNITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2bpv:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE-INHIBITOR COMPLEX  |   ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2bpw:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE-INHIBITOR COMPLEX  |   ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2bpx:B    (LYS45) to    (GLY94)  HIV-1 PROTEASE-INHIBITOR COMPLEX  |   ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2bpy:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE-INHIBITOR COMPLEX  |   ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2bpz:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE-INHIBITOR COMPLEX  |   ACID PROTEASE, HYDROLASE-HYDROLASE COMPLEX 
2bqv:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR AHA455  |   HYDROLASE/INHIBITOR, HYDROLASE/INHIBITOR COMPLEX, HIV-1 PROTEASE, INHIBITOR, DRUG DESIGN, HYDROLASE COMPLEX 
3s85:A    (LYS45) to    (GLY94)  DISCOVERY OF NEW HIV PROTEASE INHIBITORS WITH POTENTIAL FOR CONVENIENT DOSING AND REDUCED SIDE EFFECTS: A-790742 AND A-792611.  |   BETA BARREL, ACID PROTEASE, ASPARTIC-TYPE ENDOPEPIDASE ACTIVITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3s85:B    (LYS45) to    (GLY94)  DISCOVERY OF NEW HIV PROTEASE INHIBITORS WITH POTENTIAL FOR CONVENIENT DOSING AND REDUCED SIDE EFFECTS: A-790742 AND A-792611.  |   BETA BARREL, ACID PROTEASE, ASPARTIC-TYPE ENDOPEPIDASE ACTIVITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3s85:C    (GLY52) to    (GLY94)  DISCOVERY OF NEW HIV PROTEASE INHIBITORS WITH POTENTIAL FOR CONVENIENT DOSING AND REDUCED SIDE EFFECTS: A-790742 AND A-792611.  |   BETA BARREL, ACID PROTEASE, ASPARTIC-TYPE ENDOPEPIDASE ACTIVITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3s85:E    (LYS45) to    (GLY94)  DISCOVERY OF NEW HIV PROTEASE INHIBITORS WITH POTENTIAL FOR CONVENIENT DOSING AND REDUCED SIDE EFFECTS: A-790742 AND A-792611.  |   BETA BARREL, ACID PROTEASE, ASPARTIC-TYPE ENDOPEPIDASE ACTIVITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3s85:G    (LYS45) to    (GLY94)  DISCOVERY OF NEW HIV PROTEASE INHIBITORS WITH POTENTIAL FOR CONVENIENT DOSING AND REDUCED SIDE EFFECTS: A-790742 AND A-792611.  |   BETA BARREL, ACID PROTEASE, ASPARTIC-TYPE ENDOPEPIDASE ACTIVITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1bv7:A    (LYS45) to    (GLY94)  COUNTERACTING HIV-1 PROTEASE DRUG RESISTANCE: STRUCTURAL ANALYSIS OF MUTANT PROTEASES COMPLEXED WITH XV638 AND SD146, CYCLIC UREA AMIDES WITH BROAD SPECIFICITIES  |   HYDROLASE(ACID PROTEINASE) 
1bv7:B    (GLY52) to    (GLY94)  COUNTERACTING HIV-1 PROTEASE DRUG RESISTANCE: STRUCTURAL ANALYSIS OF MUTANT PROTEASES COMPLEXED WITH XV638 AND SD146, CYCLIC UREA AMIDES WITH BROAD SPECIFICITIES  |   HYDROLASE(ACID PROTEINASE) 
1bv9:B    (LYS45) to    (GLY94)  HIV-1 PROTEASE (I84V) COMPLEXED WITH XV638 OF DUPONT PHARMACEUTICALS  |   HIV-1 PROTEASE (I84V) XV638, HYDROLASE 
1bvg:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE-DMP323 COMPLEX IN SOLUTION, NMR MINIMIZED AVERAGE STRUCTURE  |   AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE, RNA-DIRECTED DNA POLYMERASE 
1bvg:B    (ARG41) to    (GLY94)  HIV-1 PROTEASE-DMP323 COMPLEX IN SOLUTION, NMR MINIMIZED AVERAGE STRUCTURE  |   AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE, RNA-DIRECTED DNA POLYMERASE 
3sa4:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF72  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3sa5:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF69  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3sa6:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF71  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3sa7:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF55  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3sa7:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF55  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3sa8:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KB83  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3saa:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF77  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3sab:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF78  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3sab:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF78  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3sac:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF80  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1odw:B    (LYS45) to    (GLY94)  NATIVE HIV-1 PROTEINASE  |   PROTEINASE, RETROPEPSIN, RETROVIRUS, HIV, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1odx:B    (GLY40) to    (GLY94)  HIV-1 PROTEINASE MUTANT A71T, V82A  |   PROTEINASE, RETROPEPSIN, RETROVIRUS, HIV, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1c6y:A    (LYS45) to    (GLY94)  ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.  |   HYDROLASE 
1c6y:B   (GLY252) to   (GLY294)  ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.  |   HYDROLASE 
1c6z:A    (LYS45) to    (GLY94)  ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1c6z:B   (ARG241) to   (GLY294)  ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1ohr:B    (GLY52) to    (GLY94)  VIRACEPT (R) (NELFINAVIR MESYLATE, AG1343): A POTENT ORALLY BIOAVAILABLE INHIBITOR OF HIV-1 PROTEASE  |   ASPARTYL PROTEASE, HYDROLASE, HIV-I PROTEASE 
2pqz:A    (ARG41) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH A PYRROLIDINE-BASED INHIBITOR  |   PROTEIN-LIGAND COMPLEX, HYDROLASE 
2pqz:B    (PRO44) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH A PYRROLIDINE-BASED INHIBITOR  |   PROTEIN-LIGAND COMPLEX, HYDROLASE 
2psu:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH CARB- AD37  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITOR, HYDROLASE 
2psv:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH CARB- KB45  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2pwc:A    (ARG41) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH A AMINO DECORATED PYRROLIDINE-BASED INHIBITOR  |   PROTEIN-LIGAND COMPLEX, HYDROLASE 
2pym:A    (LYS45) to    (GLY94)  HIV-1 PR MUTANT IN COMPLEX WITH NELFINAVIR  |   RESISTANCE; NELFINAVIR, HYDROLASE 
2pym:B    (LYS45) to    (GLY94)  HIV-1 PR MUTANT IN COMPLEX WITH NELFINAVIR  |   RESISTANCE; NELFINAVIR, HYDROLASE 
2pyn:A    (LYS45) to    (GLY94)  HIV-1 PR MUTANT IN COMPLEX WITH NELFINAVIR  |   RESISTANCE; NELFINAVIR, HYDROLASE 
2pyn:B    (LYS45) to    (GLY94)  HIV-1 PR MUTANT IN COMPLEX WITH NELFINAVIR  |   RESISTANCE; NELFINAVIR, HYDROLASE 
3so9:A    (PRO44) to    (GLY94)  DARUNAVIR IN COMPLEX WITH A HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE VARIANT  |   MULTI-DRUG RESISTANCE, HIV-1 PROTEASE, DARUNAVIR, PROTEASE INHIBITOR, HYDORLASE-HYDORLASE INHIBITOR COMPLEX 
4i8w:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH NON- PEPTIDIC INHIBITOR, GRL007  |   HIV-1 PROTEASE, HIV-1 PROTEASE-INHIBITOR COMPLEX, HYDROLASE, GRL007, PROTEASE INHIBITOR, NON-PEPTIDIC PROTEASE INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
4i8z:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH NON- PEPTIDIC INHIBITOR, GRL008  |   HIV-1 PROTEASE, HIV-1 PROTEASE-INHIBITOR COMPLEX, HYDROLASE, GRL008, NON-PEPTIDIC INHIBITOR, PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3spk:A    (LYS45) to    (GLY94)  TIPRANAVIR IN COMPLEX WITH A HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE VARIANT  |   TIPRANAVIR, MULTI-DRUG RESISTANT HIV-1 PROTEASE, HYDORLASE-HYDORLASE INHIBITOR COMPLEX 
1cpi:B    (GLY40) to    (GLY94)  REGIOSELECTIVE STRUCTURAL AND FUNCTIONAL MIMICRY OF PEPTIDES. DESIGN OF HYDROLYTICALLY STABLE CYCLIC PEPTIDOMIMETIC INHIBITORS OF HIV-1 PROTEASE  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2q3k:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF LYSINE SULFONAMIDE INHIBITOR REVEALS THE DISPLACEMENT OF THE CONSERVED FLAP WATER MOLECULE IN HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, VIRAL PROTEIN 
2q54:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF KB73 BOUND TO HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2q54:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF KB73 BOUND TO HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2q55:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF KK44 BOUND TO HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITOR, HYDROLASE 
2q55:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF KK44 BOUND TO HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITOR, HYDROLASE 
2q5k:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF LOPINAVIR BOUND TO WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2q5k:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF LOPINAVIR BOUND TO WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2q63:A    (LYS45) to    (GLY94)  HIV-1 PR MUTANT IN COMPLEX WITH NELFINAVIR  |   RESISTANCE; NELFINAVIR, HYDROLASE 
2q63:B    (LYS45) to    (GLY94)  HIV-1 PR MUTANT IN COMPLEX WITH NELFINAVIR  |   RESISTANCE; NELFINAVIR, HYDROLASE 
3fx5:A    (LYS45) to    (GLY94)  STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH POTENT INHIBITOR KNI-272 DETERMINED BY HIGH RESOLUTION X-RAY CRYSTALLOGRAPHY  |   ACID PROTEASE, HOMODIMER, PROTEASE, HYDROLASE, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3fx5:B   (GLY152) to   (GLY194)  STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH POTENT INHIBITOR KNI-272 DETERMINED BY HIGH RESOLUTION X-RAY CRYSTALLOGRAPHY  |   ACID PROTEASE, HOMODIMER, PROTEASE, HYDROLASE, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2cej:B   (PRO144) to   (GLY194)  P1' EXTENDED HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMICKING SCAFFOLD  |   HIV-1, PROTEASE, INHIBITOR, ASPARTYL PROTEASE, HYDROLASE 
2qak:A    (LYS45) to    (GLY94)  HIV-1 PR MUTANT IN COMPLEX WITH NELFINAVIR  |   HIV PROTEASE INHIBITORS; PROTEASE-INHIBITOR STRUCTURE; ISOTHERMAL CALORIMETRY; ANTIVIRAL RESISTANCE DEVELOPMENT, HYDROLASE 
2qak:B    (LYS45) to    (GLY94)  HIV-1 PR MUTANT IN COMPLEX WITH NELFINAVIR  |   HIV PROTEASE INHIBITORS; PROTEASE-INHIBITOR STRUCTURE; ISOTHERMAL CALORIMETRY; ANTIVIRAL RESISTANCE DEVELOPMENT, HYDROLASE 
2cem:A    (GLY52) to    (GLY94)  P1' EXTENDED HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMICKING SCAFFOLD  |   HIV-1, PROTEASE, INHIBITOR, ASPARTYL PROTEASE, HYDROLASE 
2qci:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE MUTANT D30N WITH POTENT ANTIVIRAL INHIBITOR GRL-98065  |   HIV-1, MUTANT D30N, PROTEASE INHIBITOR, HYDROLASE 
1d4h:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA435  |   DIMER, HYDROLASE 
1d4i:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA425  |   DIMER, HYDROLASE 
1d4k:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE COMPLEXED WITH A MACROCYCLIC PEPTIDOMIMETIC INHIBITOR  |   HIV, PROTEASE, INHIBITOR, ANTIVIRAL, STRUCTURE, HYDROLASE 
1d4l:B    (GLY52) to    (GLY94)  HIV-1 PROTEASE COMPLEXED WITH A MACROCYCLIC PEPTIDOMIMETIC INHIBITOR  |   HIV, PROTEASE, INHIBITOR, ANTIVIRAL, STRUCTURE, HYDROLASE 
1d4y:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE TRIPLE MUTANT/TIPRANAVIR COMPLEX  |   HYDROLASE, ACID PROTEASE, ASPARTYL PROTEASE 
2qd6:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE MUTANT I50V WITH POTENT ANTIVIRAL INHIBITOR GRL-98065  |   HIV-1 PROTEASE MUTANT I50V, PROTEASE INHIBITOR, HYDROLASE 
2qd7:A    (GLY40) to    (GLY94)  HIV-1 PROTEASE MUTANT V82A WITH POTENT ANTIVIRAL INHIBITOR GRL-98065  |   HIV-1 PROTEASE MUTANT V82A, PROTEASE INHIBITOR, HYDROLASE 
2qd8:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE MUTANT I84V WITH POTENT ANTIVIRAL INHIBITOR GRL-98065  |   HIV-1 PROTEASE MUTANT I84V, PROTEASE INHIBITOR, HYDROLASE 
2qhc:A    (LYS45) to    (GLY94)  THE INFLUENCE OF I47A MUTATION ON REDUCED SUSCEPTIBILITY TO THE PROTEASE INHIBITOR LOPINAVIR  |   HIV PROTEASE INHIBITORS; PROTEASE-INHIBITOR STRUCTURE; ASPARTIC PROTEASE, RESISTANT STRAIN, HYDROLASE 
2qhc:B    (LYS45) to    (GLY94)  THE INFLUENCE OF I47A MUTATION ON REDUCED SUSCEPTIBILITY TO THE PROTEASE INHIBITOR LOPINAVIR  |   HIV PROTEASE INHIBITORS; PROTEASE-INHIBITOR STRUCTURE; ASPARTIC PROTEASE, RESISTANT STRAIN, HYDROLASE 
2qhy:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-1-AC86 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2qhz:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-1-AC87 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2qi1:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-1-KK81 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2qi3:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-2-AD94 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2qi4:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-2-AD93 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2qi5:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-2-KC08 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2qi5:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-2-KC08 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2qi6:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-2-KB98 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2qi7:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-2-AD86 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
1dif:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH A DIFLUOROKETONE CONTAINING INHIBITOR A79285  |   ASPARTIC PROTEINASE 
1dif:B    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH A DIFLUOROKETONE CONTAINING INHIBITOR A79285  |   ASPARTIC PROTEINASE 
2qnn:A    (GLY40) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH A MULTIPLE DECORATED PYRROLIDINE-BASED INHIBITOR  |   PROTEIN-LIGAND COMPLEX, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, PHOSPHORYLATION, PROTEASE, RNA- BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC-FINGER 
2qnp:A    (ARG41) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH A IODO DECORATED PYRROLIDINE- BASED INHIBITOR  |   PROTEIN-LIGAND COMPLEX, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, PHOSPHORYLATION, PROTEASE, RNA- BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER 
2qnq:A    (GLY40) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH A CHLORO DECORATED PYRROLIDINE-BASED INHIBITOR  |   PROTEIN-LIGAND COMPLEX, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, PHOSPHORYLATION, PROTEASE, RNA- BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER 
3gga:G    (GLY52) to    (GLY94)  HIV PROTEASE INHIBITORS WITH PSEUDO-SYMMETRIC CORES  |   PSEUDO-SYMMETRICAL HIV PROTEASE INHIBITORS, HYDROLASE, PROTEASE 
3gga:H    (PRO44) to    (GLY94)  HIV PROTEASE INHIBITORS WITH PSEUDO-SYMMETRIC CORES  |   PSEUDO-SYMMETRICAL HIV PROTEASE INHIBITORS, HYDROLASE, PROTEASE 
3gga:B    (GLY52) to    (GLY94)  HIV PROTEASE INHIBITORS WITH PSEUDO-SYMMETRIC CORES  |   PSEUDO-SYMMETRICAL HIV PROTEASE INHIBITORS, HYDROLASE, PROTEASE 
3ggu:A    (ARG45) to    (GLY94)  HIV PR DRUG RESISTANT PATIENT'S VARIANT IN COMPLEX WITH DARUNAVIR  |   DARUNVIR, RESISTANCE, MUTATION SCORE, HIV PROTEASE, TMC-114, HYDROLASE 
3ggu:B    (ARG45) to    (GLY94)  HIV PR DRUG RESISTANT PATIENT'S VARIANT IN COMPLEX WITH DARUNAVIR  |   DARUNVIR, RESISTANCE, MUTATION SCORE, HIV PROTEASE, TMC-114, HYDROLASE 
3ggv:B    (LYS45) to    (GLY94)  HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS  |   HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE 
3ggv:F    (GLY52) to    (GLY94)  HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS  |   HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE 
3ggv:G    (GLY52) to    (GLY94)  HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS  |   HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE 
3ggv:I    (LYS45) to    (GLY94)  HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS  |   HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE 
3gi0:A   (PRO148) to   (GLY198)  CRYSTAL STRUCTURE OF A CHEMICALLY SYNTHESIZED 203 AMINO ACID 'COVALENT DIMER' [L-ALA51,D-ALA51'] HIV-1 PROTEASE MOLECULE COMPLEXED WITH JG- 365 INHIBITOR  |   BETA-BARREL, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3gi0:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF A CHEMICALLY SYNTHESIZED 203 AMINO ACID 'COVALENT DIMER' [L-ALA51,D-ALA51'] HIV-1 PROTEASE MOLECULE COMPLEXED WITH JG- 365 INHIBITOR  |   BETA-BARREL, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3gi4:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, KB60 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, PROTEASE INHIBITORS, HIV-1 PROTEASE, ASPARTYL PROTEASE, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3gi5:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, KB62 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, PROTEASE INHIBITORS, HIV-1 PROTEASE, ASPARTYL PROTEASE, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3gi6:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, AD78 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, PROTEASE INHIBITORS, HIV-1 PROTEASE, ASPARTYL PROTEASE, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2r3t:B    (LYS45) to    (GLY94)  I50V HIV-1 PROTEASE MUTANT IN COMPLEX WITH A CARBAMOYL DECORATED PYRROLIDINE-BASED INHIBITOR  |   PROTEIN-LIGAND COMPLEX, ASPARTYL PROTEASE, HYDROLASE, PROTEASE 
2r43:A    (ARG41) to    (GLY94)  I50V HIV-1 PROTEASE IN COMPLEX WITH AN AMINO DECORATED PYRROLIDINE- BASED INHIBITOR  |   PROTEIN-LIGAND COMPLEX, HYDROLASE 
4j54:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 WITH THE POTENT ANTIVIRAL INHIBITOR GRL-0519A  |   MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20, CLINICAL INHIBITOR AMPRENAVIR, POTENT ANTIVIRAL INHIBITOR GRL-0519A, POTENT ANTIVIRAL INHIBITOR GRL-02031, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4j54:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 WITH THE POTENT ANTIVIRAL INHIBITOR GRL-0519A  |   MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20, CLINICAL INHIBITOR AMPRENAVIR, POTENT ANTIVIRAL INHIBITOR GRL-0519A, POTENT ANTIVIRAL INHIBITOR GRL-02031, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4j55:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 WITH THE POTENT ANTIVIRAL INHIBITOR GRL-02031  |   MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20, CLINICAL INHIBITOR AMPRENAVIR, POTENT ANTIVIRAL INHIBITOR GRL-0519A, POTENT ANTIVIRAL INHIBITOR GRL-02031, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4j55:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 WITH THE POTENT ANTIVIRAL INHIBITOR GRL-02031  |   MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20, CLINICAL INHIBITOR AMPRENAVIR, POTENT ANTIVIRAL INHIBITOR GRL-0519A, POTENT ANTIVIRAL INHIBITOR GRL-02031, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4j5j:B   (GLY140) to   (GLY194)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 IN COMPLEX WITH AMPRENAVIR  |   MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20, CLINICAL INHIBITOR AMPRENAVIR, POTENT ANTIVIRAL INHIBITOR GRL-0519A, POTENT ANTIVIRAL INHIBITOR GRL-02031, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2r5p:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF HIV-1 SUBTYPE C PROTEASE COMPLEXED WITH INDINAVIR  |   HIV-1 SUBTYPE C, ASPARTYL PROTEASE, HYDROLASE, PROTEASE, VIRAL PROTEIN 
2r5p:D    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF HIV-1 SUBTYPE C PROTEASE COMPLEXED WITH INDINAVIR  |   HIV-1 SUBTYPE C, ASPARTYL PROTEASE, HYDROLASE, PROTEASE, VIRAL PROTEIN 
3th9:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT Q7K V32I L63I WITH A CYCLIC SULFONAMIDE INHIBITOR  |   ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3th9:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT Q7K V32I L63I WITH A CYCLIC SULFONAMIDE INHIBITOR  |   ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1ebk:C    (ARG41) to    (GLY94)  STRUCTURAL AND KINETIC ANALYSIS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE  |   HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1ebk:D   (GLY152) to   (ILE193)  STRUCTURAL AND KINETIC ANALYSIS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE  |   HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1ebk:F   (GLY152) to   (GLY194)  STRUCTURAL AND KINETIC ANALYSIS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE  |   HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1ebw:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA322  |   DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX 
1ec0:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA403  |   DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX 
1ec1:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA409  |   DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX 
1ec3:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR MSA367  |   DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX 
3tkg:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV MODEL PROTEASE PRECURSOR/SAQUINAVIR COMPLEX  |   HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3tkg:C    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV MODEL PROTEASE PRECURSOR/SAQUINAVIR COMPLEX  |   HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3tl9:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV PROTEASE MODEL PRECURSOR/SAQUINAVIR COMPLEX  |   HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3tlh:A    (LYS45) to    (GLY94)  STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITHAN EFFICIENT INHIBITOR OF FIV PR  |   HIV PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3tof:A    (GLY40) to    (GLY94)  HIV-1 PROTEASE - EPOXYDIC INHIBITOR COMPLEX (PH 6 - ORTHOROMBIC CRYSTAL FORM P212121)  |   HIV PR, EPOXIDE, IN-CRYSTAL REACTION, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3tog:B    (LYS45) to    (GLY94)  HIV-1 PROTEASE - EPOXYDIC INHIBITOR COMPLEX (PH 9 - MONOCLINIC CRYSTAL FORM P21)  |   HIV PR, EPOXIDE, IN-CRYSTAL REACTION, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3toh:A    (GLY40) to    (GLY94)  HIV-1 PROTEASE - EPOXYDIC INHIBITOR COMPLEX (PH 9 - ORTHOROMBIC CRYSTAL FORM P212121)  |   HIV PR, EPOXIDE, IN-CRYSTAL REACTION, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1qbr:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY  |   HYDROLASE (ACID PROTEINASE), ASPARTYL PROTEASE 
1qbr:B    (LYS45) to    (GLY94)  HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY  |   HYDROLASE (ACID PROTEINASE), ASPARTYL PROTEASE 
1qbu:B    (LYS45) to    (GLY94)  HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY  |   HYDROLASE (ACID PROTEINASE), ASPARTYL PROTEASE 
4ye3:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 WITH INHIBITOR GRL-4410A  |   HIV-1 PROTEASE, DRUG RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4ye3:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 WITH INHIBITOR GRL-4410A  |   HIV-1 PROTEASE, DRUG RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3ttp:A    (LYS45) to    (GLY94)  STRUCTURE OF MULTIRESISTANT HIV-1 PROTEASE IN COMPLEX WITH DARUNAVIR  |   HYDROLASE, VIRAL PRATICLE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2rkg:B    (GLY53) to    (GLY95)  HIV-1 PR RESISTANT MUTANT + LPV  |   RESISTENCE, INSERTION, HYDROLASE 
4yhq:B    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT CLINICAL ISOLATE PR20 WITH GRL-5010A  |   HIV PROTEASE, MUTANT, DRUG RESISTANT, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3h5b:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE WITH NOVEL P1'-LIGAND GRL-02031  |   HIV-1, WILD TYPE PROTEASE, PROTEASE INHIBITOR, P1'-LIGAND, AIDS, HYDROLASE 
3hau:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF CHEMICALLY SYNTHESIZED HIV-1 PROTEASE WITH REDUCED ISOSTERE MVT-101 INHIBITOR  |   BETA BARREL, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3haw:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF [L-ALA51/51']HIV-1 PROTEASE WITH REDUCED ISOSTERE MVT-101 INHIBITOR  |   BETA BARREL, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3hbo:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF CHEMICALLY SYNTHESIZED [D-ALA51/51']HIV-1 PROTEASE  |   BETA BARREL, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3u71:A    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF SOUTH AFRICAN WILD TYPE HIV-1 SUBTYPE C PROTEASE  |   BETA SHEET, APO, PROTEASE, SOUTH AFRICAN, NON-B SUBTYPE, VIRAL POLYPROTEIN, HYDROLASE 
3u7s:A    (ARG41) to    (GLY94)  HIV PR DRUG RESISTANT PATIENT'S VARIANT IN COMPLEX WITH DARUNAVIR  |   DARUNVIR, RESISTANCE, MUTATION SCORE, HIV PROTEASE, TMC-114, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3u7s:B    (LYS45) to    (GLY94)  HIV PR DRUG RESISTANT PATIENT'S VARIANT IN COMPLEX WITH DARUNAVIR  |   DARUNVIR, RESISTANCE, MUTATION SCORE, HIV PROTEASE, TMC-114, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3hdk:A    (PRO44) to    (GLY94)  CRYSTAL STRUCTURE OF CHEMICALLY SYNTHESIZED [AIB51/51']HIV-1 PROTEASE  |   BETA BARREL, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2uy0:B   (GLY152) to   (GLY194)  TWO-CARBON-ELONGATED HIV-1 PROTEASE INHIBITORS WITH A TERTIARY-ALCOHOL-CONTAINING TRANSITION-STATE MIMIC  |   HIV-1, PROTEASE, HYDROLASE, INHIBITOR,  ASPARTYL PROTEASE 
1fej:C    (GLY40) to    (GLY94)  STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES  |   HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1ffi:C    (GLY40) to    (GLY94)  STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES  |   HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1fg6:C    (ARG41) to    (GLY94)  STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES  |   HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1fgc:C    (GLY40) to    (GLY94)  STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES  |   HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3ucb:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 IN COMPLEX WITH DARUNAVIR  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3ucb:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 IN COMPLEX WITH DARUNAVIR  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3uf3:B    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20  |   HYDROLASE 
3ufn:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 IN COMPLEX WITH SAQUINAVIR  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3ufn:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 IN COMPLEX WITH SAQUINAVIR  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4k4q:B    (GLY40) to    (GLY94)  TL-3 INHIBITED TRP6ALA HIV PROTEASE WITH 3-BROMO-2,6-DIMETHOXYBENZOIC ACID BOUND IN FLAP SITE  |   FRAGMENT BINDING, EXOSITE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4k4r:B    (LYS45) to    (GLY94)  TL-3 INHIBITED TRP6ALA HIV PROTEASE WITH 1-BROMO-2-NAPTHOIC ACID BOUND IN EXOSITE  |   FRAGMENT BINDING, EXOSITE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3hlo:A   (LYS149) to   (GLY198)  CRYSTAL STRUCTURE OF CHEMICALLY SYNTHESIZED 'COVALENT DIMER' [GLY51/D- ALA51']HIV-1 PROTEASE  |   BETA BARREL, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3uhl:B    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 IN COMPLEX WITH P2-NC SUBSTRATE ANALOG  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3uhl:C    (PRO44) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 IN COMPLEX WITH P2-NC SUBSTRATE ANALOG  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3uhl:D    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 IN COMPLEX WITH P2-NC SUBSTRATE ANALOG  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2f3k:A    (GLY52) to    (GLY94)  SUBSTRATE ENVELOPE AND DRUG RESISTANCE: CRYSTAL STRUCTURE OF R01 IN COMPLEX WITH WILD-TYPE HIV-1 PROTEASE  |   SUBSTRATE ENVELOPE, DRUG RESISTANCE, HIV PROTEASE, RO1, HYDROLASE 
2f3k:B    (GLY52) to    (GLY94)  SUBSTRATE ENVELOPE AND DRUG RESISTANCE: CRYSTAL STRUCTURE OF R01 IN COMPLEX WITH WILD-TYPE HIV-1 PROTEASE  |   SUBSTRATE ENVELOPE, DRUG RESISTANCE, HIV PROTEASE, RO1, HYDROLASE 
1rl8:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF THE COMPLEX OF RESISTANT STRAIN OF HIV-1 PROTEASE(V82A MUTANT) WITH RITONAVIR  |   ASPARTIC PROTEASE, ASPARTIC PROTEASE-INHIBITOR COMPLEX, RESISTANT STRAIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4kb9:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE WITH NOVEL TRICYCLIC P2- LIGANDS GRL-0739A  |   SPARTIC ACID PROTEASE, HIV-1 PROTEASE INHIBITOR GRL-0739A, A NOVEL TRICYCLIC P2-LIGAND,, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2f81:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE MUTANT L90M COMPLEXED WITH INHIBITOR TMC114  |   HIV-1 PROTEASE-INHIBITOR COMPLEX, HYDROLASE 
2f8g:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE MUTANT I50V COMPLEXED WITH INHIBITOR TMC114  |   HIV-1 PROTEASE-INHIBITOR COMPLEX, HYDROLASE 
1g2k:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE WITH CYCLIC SULFAMIDE INHIBITOR, AHA047  |   HIV, PROTEASE INHIBITORS, HYDROLASE 
1g35:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR, AHA024  |   PROTEIN-INHIBITOR COMPLEX, HYDROLASE 
2fde:B    (LYS45) to    (ILE93)  WILD TYPE HIV PROTEASE BOUND WITH GW0385  |   HIV PROTEASE, INHIBITOR, GW0385, HYDROLASE 
4z2z:B   (GLY248) to   (LEU298)  NEW CRYSTAL STRUCTURE OF YEAST DDI1 ASPARTYL PROTEASE REVEALS SUBSTRATE ENGAGEMENT MODE  |   PROTEASE, DDI1, HYDROLASE 
1g6l:A  (LYS1045) to  (GLY1094)  1.9A CRYSTAL STRUCTURE OF TETHERED HIV-1 PROTEASE  |   HYDROLASE 
2fgu:B    (GLY52) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE T80S VARIANT IN COMPLEX WITH THE INHIBITOR SAQUINAVIR USED TO EXPLORE THE ROLE OF INVARIANT THR80 IN HIV-1 PROTEASE STRUCTURE, FUNCTION, AND VIRAL INFECTIVITY.  |   HIV PROTEASE, DRUG RESISTANCE, ENZYME KINETICS, SEQUENCE CONSERVATION, PROTEIN STRUCTURE, HYDROLASE 
2fgv:A    (GLY52) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE T80N VARIANT IN COMPLEX WITH THE INHIBITOR SAQUINAVIR USED TO EXPLORE THE ROLE OF INVARIANT THR80 IN HIV-1 PROTEASE STRUCTURE, FUNCTION, AND VIRAL INFECTIVITY.  |   HIV PROTEASE, DRUG RESISTANCE, ENZYME KINETICS, SEQUENCE CONSERVATION, PROTEIN STRUCTURE, HYDROLASE 
4z4x:B   (GLY140) to   (GLY194)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20D25N WITH OPEN FLAP  |   HIV-1 PROTEASE, HYDROLASE 
2fle:B    (LYS45) to    (GLY94)  STRUCTURAL ANALYSIS OF ASYMMETRIC INHIBITOR BOUND TO THE HIV-1 PROTEASE V82A MUTANT  |   HIV-1 PROTEASE, INHIBITOR, RESISTANCE, INDUCED FIT, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
2fns:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE INACTIVE (D25N) HIV-1 PROTEASE COMPLEXED WITH WILD-TYPE HIV-1 NC-P1 SUBSTRATE.  |   STRUCTURAL INTERMEDIATE, SUBSTRATE RECOGNITION, HIV-1 PROTEASE, NC-P1 SUBSTRATE, DRUG RESISTANCE, FLAP CONFORMATION, HYDROLASE 
2fnt:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF A DRUG-RESISTANT (V82A) INACTIVE (D25N) HIV-1 PROTEASE COMPLEXED WITH AP2V VARIANT OF HIV-1 NC-P1 SUBSTRATE.  |   STRUCTURAL INTERMEDIATE, SUBSTRATE RECOGNITION, HIV-1 PROTEASE, NC-P1 SUBSTRATE, DRUG RESISTANCE, FLAP CONFORMATION, HYDROLASE 
1sbg:A    (LYS45) to    (GLY94)  AN ORALLY-BIOAVAILABLE HIV-1 PROTEASE INHIBITOR CONTAINING AN IMIDAZOLE-DERIVED PEPTIDE BOND REPLACEMENT. CRYSTALLOGRAPHIC AND PHARMACOKINETIC ANALYSIS  |   HYDROLASE(ACID PROTEASE) 
1sdv:B   (PRO144) to   (GLY194)  CRYSTAL STRUCTURES OF HIV PROTEASE V82A AND L90M MUTANTS REVEAL CHANGES IN INDINAVIR BINDING SITE.  |   DRUG RESISTANCE; HIV-1 PROTEASE, HYDROLASE 
2fxd:A    (GLY52) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE IRM MUTANT COMPLEXED WITH ATAZANAVIR (BMS-232632)  |   HUMAN IMMUNODEFICIENCY VIRUS (HIV), HIV-1 PROTEASE, REYATAZ, ATAZANAVIR, BMS-232632, HYDROLASE 
2fxd:B    (GLY40) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE IRM MUTANT COMPLEXED WITH ATAZANAVIR (BMS-232632)  |   HUMAN IMMUNODEFICIENCY VIRUS (HIV), HIV-1 PROTEASE, REYATAZ, ATAZANAVIR, BMS-232632, HYDROLASE 
1gnn:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE MUTANT WITH VAL 82 REPLACED BY ASN (V82N) COMPLEXED WITH U89360E (INHIBITOR)  |   ASPARTIC PROTEASE, HIV, MUTANT, INHIBITOR, U-89360E, HYDROLASE (ACID PROTEASE) 
1gno:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE (WILD TYPE) COMPLEXED WITH U89360E (INHIBITOR)  |   ASPARTIC PROTEASE, HIV, MUTANT, INHIBITOR, U-89360E, HYDROLASE (ACID PROTEASE) 
1sip:A    (LYS45) to    (GLY94)  ALTERNATIVE NATIVE FLAP CONFORMATION REVEALED BY 2.3 ANGSTROMS RESOLUTION STRUCTURE OF SIV PROTEINASE  |   HYDROLASE(ACID PROTEINASE) 
4zip:A    (LYS45) to    (GLY94)  HIV-1 WILD TYPE PROTEASE WITH GRL-0648A (A ISOPHTHALAMIDE-DERIVED P2- LIGAND)  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1sp5:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH A PRODUCT OF AUTOPROTEOLYSIS  |   PRODUCT, PEPTIDE, AUTOPROTEOLYSIS, SELF-DIGESTION, AUTODIGESTION, ASPARTIC PROTEASE, HIV, PROTEASE, COMPLEX(ASPARTIC PROTEASE/PEPTIDE), HYDROLASE 
3i7e:B    (GLY40) to    (GLY94)  CO-CRYSTAL STRUCTURE OF HIV-1 PROTEASE BOUND TO A MUTANT RESISTANT INHIBITOR UIC-98038  |   AIDS, HIV, HIV PRTEASE, HIV-PROTEASE INHIBITOR, DRUG DESIGN, ASPARTIC PROTEASE, ACID PROTEASE, STRUCTURE BASED DRUG DESIGN, ASPARTYL PROTEASE, HYDROLASE, PROTEASE 
3ia9:B    (PRO44) to    (GLY94)  CRYSTAL STRUCTURE OF A CHEMICALLY SYNTHESIZED [D25N]HIV-1 PROTEASE MOLECULE COMPLEXED WITH MVT-101 REDUCED ISOSTERE INHIBITOR  |   BETA-SHEET, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3vf5:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT I47V WITH NOVEL P1'-LIGANDS GRL-02031  |   PROTEASE INHIBITOR,P1'-LIGAND, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3vfb:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT N88D WITH NOVEL P1'-LIGANDS GRL-02031  |   PROTEASE INHIBITOR,P1'-LIGAND, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3iaw:A   (LYS149) to   (GLY198)  CRYSTAL STRUCTURE OF A CHEMICALLY SYNTHESIZED 203 AMINO ACID 'COVALENT DIMER' [GLY51;AIB51']HIV-1 PROTEASE MOLECULE COMPLEXED WITH MVT-101 REDUCED ISOSTERE INHIBITOR AT 1.6 A RESOLUTION  |   ASYMMETRIC DIMER, COVALENT DIMER, BETA-SHEET, HYDROLASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
1t3r:B    (LYS45) to    (GLY94)  HIV PROTEASE WILD-TYPE IN COMPLEX WITH TMC114 INHIBITOR  |   HIV-1 PROTEASE; DRUG RESISTANCE; THERMODYNAMICS; SUBSTRATE ENVELOPE, HYDROLASE 
1t7k:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH ARYLSULFONAMIDE AZACYCLIC UREA  |   HIV PROTEASE, ARYLSULFONAMIDE AZACYCLIC UREA, HYDROLASE 
1tcw:B    (LYS45) to    (GLY94)  SIV PROTEASE COMPLEXED WITH INHIBITOR SB203386  |   AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE, RNA-DIRECTED DNA POLYMERASE, ACID PROTEASE, HYDROLASE (ACID PROTEASE) 
1tcx:A    (GLY52) to    (GLY94)  HIV TRIPLE MUTANT PROTEASE COMPLEXED WITH INHIBITOR SB203386  |   AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE, RNA-DIRECTED DNA POLYMERASE, ACID PROTEASE, HYDROLASE (ACID PROTEASE) 
1tcx:B    (LYS45) to    (GLY94)  HIV TRIPLE MUTANT PROTEASE COMPLEXED WITH INHIBITOR SB203386  |   AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE, RNA-DIRECTED DNA POLYMERASE, ACID PROTEASE, HYDROLASE (ACID PROTEASE) 
1hih:A    (LYS45) to    (GLY94)  COMPARATIVE ANALYSIS OF THE X-RAY STRUCTURES OF HIV-1 AND HIV-2 PROTEASES IN COMPLEX WITH CGP 53820, A NOVEL PSEUDOSYMMETRIC INHIBITOR  |   ASPARTATE PROTEASE, INHIBITED, HIV, HYDROLASE (ASPARTIC PROTEINASE) 
1hih:B    (GLY52) to    (GLY94)  COMPARATIVE ANALYSIS OF THE X-RAY STRUCTURES OF HIV-1 AND HIV-2 PROTEASES IN COMPLEX WITH CGP 53820, A NOVEL PSEUDOSYMMETRIC INHIBITOR  |   ASPARTATE PROTEASE, INHIBITED, HIV, HYDROLASE (ASPARTIC PROTEINASE) 
2hb3:A    (LYS45) to    (GLY94)  WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH POTENT INHIBITOR GRL06579  |   ACTIVE-SITE CAVITY PROTEASE INHIBITOR CATALYTIC ASPARTIC ACID, HYDROLASE 
2hb4:A    (GLY40) to    (GLY94)  STRUCTURE OF HIV PROTEASE NL4-3 IN AN UNLIGANDED STATE  |   HIV, PROTEASE, ASPARTYL, RETROVIRUS, HYDROLASE 
1hos:A    (LYS45) to    (GLY94)  INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE BY A C2- SYMMETRIC PHOSPHINATE SYNTHESIS AND CRYSTALLOGRAPHIC ANALYSIS  |   HYDROLASE(ACID PROTEINASE) 
1hos:B    (LYS45) to    (GLY94)  INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE BY A C2- SYMMETRIC PHOSPHINATE SYNTHESIS AND CRYSTALLOGRAPHIC ANALYSIS  |   HYDROLASE(ACID PROTEINASE) 
1hps:A    (LYS45) to    (GLY94)  RATIONAL DESIGN, SYNTHESIS AND CRYSTALLOGRAPHIC ANALYSIS OF A HYDROXYETHYLENE-BASED HIV-1 PROTEASE INHIBITOR CONTAINING A HETEROCYCLIC P1'-P2' AMIDE BOND ISOSTERE  |   HYDROLASE(ACID PROTEINASE) 
1hpv:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH VX-478, A POTENT AND ORALLY BIOAVAILABLE INHIBITOR OF THE ENZYME  |   HYDROLASE (ACID PROTEINASE) 
1hpx:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE COMPLEXED WITH THE INHIBITOR KNI-272  |   ACID PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1tsq:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF AP2V SUBSTRATE VARIANT OF NC-P1 DECAMER PEPTIDE IN COMPLEX WITH V82A/D25N HIV-1 PROTEASE MUTANT  |   CO-EVOLUTION, NUCLEOCAPDIS, SUBSTRATE RECOGNITION, HIV-1 PROTEASE, HYDROLASE/VIRAL PROTEIN COMPLEX 
1tsq:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF AP2V SUBSTRATE VARIANT OF NC-P1 DECAMER PEPTIDE IN COMPLEX WITH V82A/D25N HIV-1 PROTEASE MUTANT  |   CO-EVOLUTION, NUCLEOCAPDIS, SUBSTRATE RECOGNITION, HIV-1 PROTEASE, HYDROLASE/VIRAL PROTEIN COMPLEX 
1tsu:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF DECAMER NCP1 SUBSTRATE PEPTIDE IN COMPLEX WITH WILD-TYPE D25N HIV-1 PROTEASE VARIANT  |   CO-EVOLUTION, NUCLEOCAPDIS, SUBSTRATE RECOGNITION, HIV-1 PROTEASE, VIRAL PROTEIN/HYDROLASE COMPLEX 
1tsu:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF DECAMER NCP1 SUBSTRATE PEPTIDE IN COMPLEX WITH WILD-TYPE D25N HIV-1 PROTEASE VARIANT  |   CO-EVOLUTION, NUCLEOCAPDIS, SUBSTRATE RECOGNITION, HIV-1 PROTEASE, VIRAL PROTEIN/HYDROLASE COMPLEX 
4ll3:A    (LYS45) to    (GLY94)  STRUCTURE OF WILD-TYPE HIV PROTEASE IN COMPLEX WITH DARUNAVIR  |   HYDROLASE INHIBITOR-DARUNAVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, HIV-1 PROTEASE, TMC114 
4ll3:B    (LYS45) to    (GLY94)  STRUCTURE OF WILD-TYPE HIV PROTEASE IN COMPLEX WITH DARUNAVIR  |   HYDROLASE INHIBITOR-DARUNAVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, HIV-1 PROTEASE, TMC114 
3ixo:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF UNCOMPLEXED HIV_1 PROTEASE SUBTYPE A  |   HIV-1 PROTEASE, SUBTYPE A, UNCOMPLEXED, ASPARTYL PROTEASE, HYDROLASE, MULTIFUNCTIONAL ENZYME, NUCLEOTIDYLTRANSFERASE, PROTEASE, RNA- DIRECTED DNA POLYMERASE, TRANSFERASE 
3ixo:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF UNCOMPLEXED HIV_1 PROTEASE SUBTYPE A  |   HIV-1 PROTEASE, SUBTYPE A, UNCOMPLEXED, ASPARTYL PROTEASE, HYDROLASE, MULTIFUNCTIONAL ENZYME, NUCLEOTIDYLTRANSFERASE, PROTEASE, RNA- DIRECTED DNA POLYMERASE, TRANSFERASE 
1hsg:B    (PRO44) to    (GLY94)  CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L- 735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES  |   HYDROLASE (ACID PROTEINASE) 
1hsi:B    (SER43) to    (GLY94)  CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L- 735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES  |   HYDROLASE (ACID PROTEINASE) 
1htf:B    (LYS45) to    (GLY94)  X-RAY CRYSTALLOGRAPHIC STUDIES OF A SERIES OF PENICILLIN- DERIVED ASYMMETRIC INHIBITORS OF HIV-1 PROTEASE  |   HYDROLASE(ACID PROTEINASE) 
1htg:A    (GLY52) to    (GLY94)  X-RAY CRYSTALLOGRAPHIC STUDIES OF A SERIES OF PENICILLIN- DERIVED ASYMMETRIC INHIBITORS OF HIV-1 PROTEASE  |   HYDROLASE(ACID PROTEINASE) 
2whh:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE TETHERED DIMER Q-PRODUCT COMPLEX ALONG WITH NUCLEOPHILIC WATER MOLECULE  |   PROTEASE, HYDROLASE, DRUG DESIGN, TRANSFERASE, NUCLEOTIDYLTRANSFERASE, RNA-DIRECTED DNA POLYMERASE, CATALYTIC MECHANISM, MULTIFUNCTIONAL ENZYME, TRANSITION STATE, ASPARTYL PROTEASE 
2whh:A  (LYS1045) to  (GLY1094)  HIV-1 PROTEASE TETHERED DIMER Q-PRODUCT COMPLEX ALONG WITH NUCLEOPHILIC WATER MOLECULE  |   PROTEASE, HYDROLASE, DRUG DESIGN, TRANSFERASE, NUCLEOTIDYLTRANSFERASE, RNA-DIRECTED DNA POLYMERASE, CATALYTIC MECHANISM, MULTIFUNCTIONAL ENZYME, TRANSITION STATE, ASPARTYL PROTEASE 
1hvc:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF A TETHERED DIMER OF HIV-1 PROTEASE COMPLEXED WITH AN INHIBITOR  |   HYDROLASE(ACID PROTEASE) 
1hvi:B    (GLY52) to    (GLY94)  INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE  |   HYDROLASE(ACID PROTEASE) 
1hvj:B    (GLY52) to    (GLY94)  INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE  |   HYDROLASE(ACID PROTEASE) 
1hvk:B    (GLY52) to    (GLY94)  INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE  |   HYDROLASE(ACID PROTEASE) 
1hvr:B    (LYS45) to    (GLY94)  RATIONAL DESIGN OF POTENT, BIOAVAILABLE, NONPEPTIDE CYCLIC UREAS AS HIV PROTEASE INHIBITORS  |   HYDROLASE, ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1hxw:B    (LYS45) to    (GLY94)  HIV-1 PROTEASE DIMER COMPLEXED WITH A-84538  |   ASPARTYL PROTEASE, HYDROLASE, ASPARTIC PROTEINASE, HIV, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
2hpe:B    (ASN41) to    (GLY94)  COMPARISON OF THE STRUCTURES OF HIV-2 PROTEASE COMPLEXES IN THREE CRYSTAL SPACE GROUPS WITH AN HIV-1 PROTEASE COMPLEX STRUCTURE  |   HYDROLASE(ACID PROTEASE) 
2hpf:A    (LYS45) to    (GLY94)  COMPARISON OF THE STRUCTURES OF HIV-2 PROTEASE COMPLEXES IN THREE CRYSTAL SPACE GROUPS WITH AN HIV-1 PROTEASE COMPLEX STRUCTURE  |   HYDROLASE(ACID PROTEASE) 
2hpf:B    (ASN41) to    (GLY94)  COMPARISON OF THE STRUCTURES OF HIV-2 PROTEASE COMPLEXES IN THREE CRYSTAL SPACE GROUPS WITH AN HIV-1 PROTEASE COMPLEX STRUCTURE  |   HYDROLASE(ACID PROTEASE) 
2wl0:B   (GLY152) to   (GLY194)  HIV-1 PROTEASE INHIBITORS CONTAINING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMIC WITH IMPROVED CELL-BASED ANTIVIRAL ACTIVITY  |   TRANSITION-STATE MIMIC, INHIBITOR, HYDROLASE 
2hs1:A    (LYS45) to    (GLY94)  ULTRA-HIGH RESOLUTION X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE V32I MUTANT WITH TMC114 (DARUNAVIR) INHIBITOR  |   ULTRA-HIGH RESOLUTION ACTIVE SITE SURFACE BINDING SITE, HYDROLASE 
2hs1:B   (GLY152) to   (GLY194)  ULTRA-HIGH RESOLUTION X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE V32I MUTANT WITH TMC114 (DARUNAVIR) INHIBITOR  |   ULTRA-HIGH RESOLUTION ACTIVE SITE SURFACE BINDING SITE, HYDROLASE 
2hs2:B   (GLY152) to   (GLY194)  CRYSTAL STRUCTURE OF M46L MUTANT OF HIV-1 PROTEASE COMPLEXED WITH TMC114 (DARUNAVIR)  |   ASPARTIC PROTEASE ACTIVE SITE SURFACE BINDING SITE, HYDROLASE 
1u8g:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF A HIV-1 PROTEASE IN COMPLEX WITH PEPTIDOMIMETIC INHIBITOR KI2-PHE-GLU-GLU-NH2  |   ASPARTYL PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS, INHIBITOR DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1u8g:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF A HIV-1 PROTEASE IN COMPLEX WITH PEPTIDOMIMETIC INHIBITOR KI2-PHE-GLU-GLU-NH2  |   ASPARTYL PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS, INHIBITOR DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2i0a:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF KB-19 COMPLEXED WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
2i0d:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF AD-81 COMPLEXED WITH WILD TYPE HIV-1 PROTEASE  |   DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE 
1idb:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURES OF HIV-2 PROTEASE IN COMPLEX WITH INHIBITORS CONTAINING THE HYDROXYETHYLAMINE DIPEPTIDE ISOSTERE  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2i4u:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE WITH TMC-126  |   PROTEIN INHIBITOR COMPLEX, HYDROLASE 
2i4w:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE WT WITH GS-8374  |   HIV-1 PROTEASE INHIBITOR, HYDROLASE 
2i4x:A    (GLY52) to    (ILE93)  HIV-1 PROTEASE I84V, L90M WITH GS-8374  |   HIV-1 PROTEASE I84VL90M INHIBITOR, HYDROLASE 
2idw:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A POTENT NON-PEPTIDE INHIBITOR (UIC-94017)  |   HIV-1 PROTEASE, MUTANT, DIMER, INHIBITOR, UIC-94017, HYDROLASE 
4m8x:A    (GLY40) to    (GLY94)  GS-8374, A NOVEL PHOSPHONATE-CONTAINING INHIBITOR OF HIV-1 PROTEASE, EFFECTIVELY INHIBITS HIV PR MUTANTS WITH AMINO ACID INSERTIONS  |   HIV PROTEASE, ASPARTIC PROTEASE, GS8374, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4m8x:B    (GLY40) to    (GLY94)  GS-8374, A NOVEL PHOSPHONATE-CONTAINING INHIBITOR OF HIV-1 PROTEASE, EFFECTIVELY INHIBITS HIV PR MUTANTS WITH AMINO ACID INSERTIONS  |   HIV PROTEASE, ASPARTIC PROTEASE, GS8374, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2ieo:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT I84V WITH A POTENT NON-PEPTIDE INHIBITOR (UIC-94017)  |   HIV-1 PROTEASE, MUTANT, I84V, DIMER, INHIBITOR, UIC-94017, TMC114, DARUNAVIR, HYDROLASE 
1ivp:A    (ASN41) to    (GLY94)  THE CRYSTALLOGRAPHIC STRUCTURE OF THE PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 WITH TWO SYNTHETIC PEPTIDIC TRANSITION STATE ANALOG INHIBITORS  |   ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1ivp:B    (LYS45) to    (GLY94)  THE CRYSTALLOGRAPHIC STRUCTURE OF THE PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 WITH TWO SYNTHETIC PEPTIDIC TRANSITION STATE ANALOG INHIBITORS  |   ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1ivq:B    (ASN41) to    (GLY94)  THE CRYSTALLOGRAPHIC STRUCTURE OF THE PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 WITH TWO SYNTHETIC PEPTIDIC TRANSITION STATE ANALOG INHIBITORS  |   ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4mc1:A    (LYS45) to    (GLY94)  HIV PROTEASE IN COMPLEX WITH SA526P  |   CARBAMATES, DRUG DESIGN, HIV PROTEASE INHIBITORS, PROTEIN BINDING, STEREOISOMERISM, STRUCTURE-ACTIVITY RELATIONSHIP, THIAZEPINES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4mc1:B    (PRO44) to    (GLY94)  HIV PROTEASE IN COMPLEX WITH SA526P  |   CARBAMATES, DRUG DESIGN, HIV PROTEASE INHIBITORS, PROTEIN BINDING, STEREOISOMERISM, STRUCTURE-ACTIVITY RELATIONSHIP, THIAZEPINES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4mc2:A    (LYS45) to    (GLY94)  HIV PROTEASE IN COMPLEX WITH SA525P  |   CARBAMATES, DRUG DESIGN, HIV PROTEASE INHIBITORS, PROTEIN BINDING, STEREOISOMERISM, STRUCTURE-ACTIVITY RELATIONSHIP, THIAZEPINES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4mc2:B    (PRO44) to    (GLY94)  HIV PROTEASE IN COMPLEX WITH SA525P  |   CARBAMATES, DRUG DESIGN, HIV PROTEASE INHIBITORS, PROTEIN BINDING, STEREOISOMERISM, STRUCTURE-ACTIVITY RELATIONSHIP, THIAZEPINES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4mc6:A    (LYS45) to    (GLY94)  HIV PROTEASE IN COMPLEX WITH SA499  |   CARBAMATES, DRUG DESIGN, HIV PROTEASE INHIBITORS, PROTEIN BINDING, STEREOISOMERISM, STRUCTURE-ACTIVITY RELATIONSHIP, THIAZEPINES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4mc6:B    (PRO44) to    (GLY94)  HIV PROTEASE IN COMPLEX WITH SA499  |   CARBAMATES, DRUG DESIGN, HIV PROTEASE INHIBITORS, PROTEIN BINDING, STEREOISOMERISM, STRUCTURE-ACTIVITY RELATIONSHIP, THIAZEPINES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4mc9:A    (LYS45) to    (GLY94)  HIV PROTEASE IN COMPLEX WITH AA74  |   CARBAMATES, DRUG DESIGN, HIV PROTEASE INHIBITORS, PROTEIN BINDING, STEREOISOMERISM, STRUCTURE-ACTIVITY RELATIONSHIP, THIAZEPINES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4mc9:B    (PRO44) to    (GLY94)  HIV PROTEASE IN COMPLEX WITH AA74  |   CARBAMATES, DRUG DESIGN, HIV PROTEASE INHIBITORS, PROTEIN BINDING, STEREOISOMERISM, STRUCTURE-ACTIVITY RELATIONSHIP, THIAZEPINES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1izh:A    (LYS45) to    (GLY94)  INHIBITOR OF HIV PROTEASE WITH UNUSUAL BINDING MODE POTENTLY INHIBITING MULTI-RESISTANT PROTEASE MUTANTS  |   HIV-1 PROTEINASE, POTENT INHIBITOR, SUBSITE BINDING, HYDROLASE 
1izi:B    (LYS45) to    (GLY94)  INHIBITOR OF HIV PROTEASE WITH UNUSUAL BINDING MODE POTENTLY INHIBITING MULTI-RESISTANT PROTEASE MUTANTS  |   HIV-1 PROTEINASE, TRIPLE MUTANT, POTENT INHIBITOR, SUBSITE BINDING, HYDROLASE 
5agz:A    (LYS45) to    (GLY94)  DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II)  |   HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL 
5ah6:A    (LYS45) to    (GLY94)  DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II)  |   HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL 
5ah6:B   (PRO144) to   (GLY194)  DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II)  |   HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL 
5ah7:A    (LYS45) to    (GLY94)  DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON-PEPTIDAL HIV-1 PROTEASE INHIBITORS (II)  |   HYDROLASE, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL 
5ah8:B   (PRO144) to   (GLY194)  DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON-PEPTIDAL HIV-1 PROTEASE INHIBITORS (II)  |   HYDROLASE, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL 
5ah9:A    (LYS45) to    (GLY94)  DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II)  |   HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL 
5aha:B   (PRO144) to   (GLY194)  DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II)  |   HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL 
5ahb:B   (PRO144) to   (GLY194)  DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON-PEPTIDAL HIV-1 PROTEASE INHIBITORS (II)  |   HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL 
1vij:B    (LYS45) to    (GLY94)  HIV-1 PROTEASE COMPLEXED WITH THE INHIBITOR HOE/BAY 793 HEXAGONAL FORM  |   ASPARTYL PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS, HOE/BAY 793: INHIBITOR DESIGN 
1vik:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE COMPLEXED WITH THE INHIBITOR HOE/BAY 793 ORTHORHOMBIC FORM  |   ASPARTYL PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS, HOE/BAY 793: INHIBITOR DESIGN 
2j9j:B    (GLY52) to    (GLY94)  ATOMIC-RESOLUTION CRYSTAL STRUCTURE OF CHEMICALLY-SYNTHESIZED HIV-1 PROTEASE COMPLEXED WITH INHIBITOR JG-365  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASE, HYDROLASE, HIGH RESOLUTION, RNA-DIRECTED DNA POLYMERASE, ASPARTYL PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS 1, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
2j9k:B    (GLY52) to    (GLY94)  ATOMIC-RESOLUTION CRYSTAL STRUCTURE OF CHEMICALLY-SYNTHESIZED HIV-1 PROTEASE COMPLEXED WITH INHIBITOR MVT-101  |   PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, ASPARTYL PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS 1 
5b18:A    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF A DARUNAVIR RESISTANT HIV-1 PROTEASE  |   HIV-1 PROTEASE, DRUG RESISTANCE, DARUNAVIR, FLAP, HYDROLASE 
5b18:D    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF A DARUNAVIR RESISTANT HIV-1 PROTEASE  |   HIV-1 PROTEASE, DRUG RESISTANCE, DARUNAVIR, FLAP, HYDROLASE 
2je4:B    (GLY52) to    (GLY94)  ATOMIC-RESOLUTION CRYSTAL STRUCTURE OF CHEMICALLY-SYNTHESIZED HIV-1 PROTEASE IN COMPLEX WITH JG-365  |   PROTEASE, HYDROLASE, HIGH RESOLUTION, ASPARTYL PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS 1, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1w5w:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH FLUORO SUBSTITUTED DIOL- BASED C2-SYMMETRIC INHIBITOR  |   HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE, DIMER, PROTEIN-INHIBITOR COMPLEX 
1w5x:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH FLUORO SUBSTITUTED DIOL- BASED C2-SYMMETRIC INHIBITOR  |   HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE, DIMER, PROTEIN-INHIBITOR COMPLEX 
1w5y:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH FLUORO SUBSTITUTED DIOL- BASED C2-SYMMETRIC INHIBITOR  |   HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE, DIMER, PROTEIN-INHIBITOR COMPLEX 
1k1t:A    (GLY40) to    (GLY94)  COMBINING MUTATIONS IN HIV-1 PROTEASE TO UNDERSTAND MECHANISMS OF RESISTANCE  |   HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5bry:A    (LYS45) to    (GLY94)  HIV-1 WILD TYPE PROTEASE WITH GRL-011-11A (A METHYLAMINE BIS- TETRAHYDROFURAN P2-LIGAND, SULFONAMIDE ISOSTERE DERIVATE)  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1k2b:A    (LYS45) to    (GLY94)  COMBINING MUTATIONS IN HIV-1 PROTEASE TO UNDERSTAND MECHANISMS OF RESISTANCE  |   HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5bs4:A    (LYS45) to    (GLY94)  HIV-1 WILD TYPE PROTEASE WITH GRL-047-11A (A METHYLAMINE BIS- TETRAHYDROFURAN P2-LIGAND, 4-AMINO SULFONAMIDE DERIVATIVE)  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1wbk:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH ASYMMETRIC INHIBITOR, BEA568  |   HYDROLASE/INHIBITOR, HYDROLASE/INHIBITOR COMPLEX, AIDS, ASPARTYL PROTEASE, DIMER, HYDROLASE, HYDROLASE/HYDROLASE INHIBITOR, PROTEIN-INHIBITOR COMPLEX 
1wbm:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH SYMMETRIC INHIBITOR, BEA450  |   HYDROLASE/INHIBITOR, HYDROLASE/INHIBITOR COMPLEX, AIDS, ASPARTYL PROTEASE, DIMER, HYDROLASE, HYDROLASE/HYDROLASE INHIBITOR, PROTEIN-INHIBITOR COMPLEX 
2xyf:B   (GLY152) to   (GLY194)  HIV-1 INHIBITORS WITH A TERTIARY-ALCOHOL-CONTAINING TRANSITION-STATE MIMIC AND VARIOUS P2 AND P1 PRIME SUBSTITUENTS  |   HYDROLASE, AIDS 
4njt:A    (ARG45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH DARUNAVIR  |   MULTIDRUG-RESISTANCE, HIV-1 PROTEASE, DARUNAVIR, NON-PEPTIDIC INHIBITOR, PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4njt:C    (ARG41) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH DARUNAVIR  |   MULTIDRUG-RESISTANCE, HIV-1 PROTEASE, DARUNAVIR, NON-PEPTIDIC INHIBITOR, PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4nju:A    (ARG45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH TIPRANAVIR  |   MULTIDRUG-RESISTANCE, HIV-1 PROTEASE, TIPRANAVIR, TPV, PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4nju:C    (ARG45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH TIPRANAVIR  |   MULTIDRUG-RESISTANCE, HIV-1 PROTEASE, TIPRANAVIR, TPV, PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4njv:C    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH RITONAVIR  |   MULTIDRUG-RESISTANCE, HIV-1 PROTEASE, RITONAVIR, RIT, PROTEASE INHIBITOR, KALETRA, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3zps:A    (LYS45) to    (GLY94)  DESIGN AND SYNTHESIS OF P1-P3 MACROCYCLIC TERTIARY ALCOHOL COMPRISING HIV-1 PROTEASE INHIBITORS  |   HYDROLASE, PROTEASE INHIBITOR, RATIONAL DRUG DESIGN, 
3zpt:A    (LYS45) to    (GLY94)  DESIGN AND SYNTHESIS OF P1-P3 MACROCYCLIC TERTIARY ALCOHOL COMPRISING HIV-1 PROTEASE INHIBITORS  |   HYDROLASE, RATIONAL DRUG DESIGN, MACROCYCLIC TERTIARY ALCOHOL 
3zpu:A    (LYS45) to    (GLY94)  DESIGN AND SYNTHESIS OF P1-P3 MACROCYCLIC TERTIARY ALCOHOL COMPRISING HIV-1 PROTEASE INHIBITORS  |   HYDROLASE, PROTEASE INHIBITOR, RATIONAL DRUG DESIGN 
2nmz:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A INHIBITOR SAQUINAVIR  |   HIV-1 PROTEASE, MUTANT, V82A, DIMER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2nmy:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A INHIBITOR SAQUINAVIR  |   HIV-1 PROTEASE, MUTANT, V82A, DIMER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2nmy:B   (PRO144) to   (GLY194)  CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A INHIBITOR SAQUINAVIR  |   HIV-1 PROTEASE, MUTANT, V82A, DIMER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5c9b:A   (THR166) to   (LYS218)  CRYSTAL STRUCTURE OF A RETROPEPSIN-LIKE ASPARTIC PROTEASE FROM RICKETTSIA CONORII  |   PEPSIN, APRICK, HYDROLASE 
5c9d:B   (THR166) to   (LYS218)  CRYSTAL STRUCTURE OF A RETROPEPSIN-LIKE ASPARTIC PROTEASE FROM RICKETTSIA CONORII  |   PEPSIN, APRICK, HYDROLASE 
5c9f:A   (THR166) to   (LYS218)  CRYSTAL STRUCTURE OF A RETROPEPSIN-LIKE ASPARTIC PROTEASE FROM RICKETTSIA CONORII  |   PEPSIN, APRICK, HYDROLASE 
5c9f:D   (LEU163) to   (LYS218)  CRYSTAL STRUCTURE OF A RETROPEPSIN-LIKE ASPARTIC PROTEASE FROM RICKETTSIA CONORII  |   PEPSIN, APRICK, HYDROLASE 
2nnp:A    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT I84V WITH A INHIBITOR SAQUINAVIR  |   HIV-1 PROTEASE, MUTANT, I84V, DIMER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1kzk:A    (GLY52) to    (GLY94)  JE-2147-HIV PROTEASE COMPLEX  |   HIV PROTEASE COMPLEX, ANISOTROPIC DISPLACEMENT PARAMETERS, VIRAL PROTEIN, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1kzk:B    (GLY40) to    (GLY94)  JE-2147-HIV PROTEASE COMPLEX  |   HIV PROTEASE COMPLEX, ANISOTROPIC DISPLACEMENT PARAMETERS, VIRAL PROTEIN, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3jw2:A    (LYS45) to    (ILE93)  HIV-1 PROTEASE MUTANT G86S WITH DARUNAVIR  |   HIV-1 PROTEASE, MUTANT G86S, INHIBITOR, DARUNAVIR, AIDS, ASPARTYL PROTEASE, METAL-BINDING, HYDROLASE 
4obd:A    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (L449F/S451N)  |   CO-EVOLUTION, RESISTANCE, HYDROLASES, HYDROLASE 
4obd:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (L449F/S451N)  |   CO-EVOLUTION, RESISTANCE, HYDROLASES, HYDROLASE 
4obd:C    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (L449F/S451N)  |   CO-EVOLUTION, RESISTANCE, HYDROLASES, HYDROLASE 
4obf:A    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE VARIANT (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (S451N)  |   CO-EVOLUTION, RESISTANCE, HYDROLASE 
4obf:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE VARIANT (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (S451N)  |   CO-EVOLUTION, RESISTANCE, HYDROLASE 
4obf:D    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE VARIANT (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (S451N)  |   CO-EVOLUTION, RESISTANCE, HYDROLASE 
4obg:A    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE.  |   CO-EVOLUTION, RESISTANCE, HYDROLASE 
4obg:C    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE.  |   CO-EVOLUTION, RESISTANCE, HYDROLASE 
4obh:B    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (L449F)  |   CO-EVOLUTION, RESISTANCE, HYDROLASE 
4obj:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (S451N)  |   CO-EVOLUTION, RESISTANCE, HYDROLASE 
4obj:B    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (S451N)  |   CO-EVOLUTION, RESISTANCE, HYDROLASE 
4obk:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (L449F/S451N)  |   CO-EVOLUTION, RESISTANCE, HYDROLASE 
2nxd:B    (LYS45) to    (ILE93)  STRUCTURE OF HIV-1 PROTEASE D25N COMPLEXED WITH RT-RH ANALOGUE PEPTIDE GLY-ALA-ASP-ILE-PHE*TYR-LEU-ASP-GLY-ALA  |   PEPTIDE DESIGN; MOLECULAR DYNAMICS; HIV PROTEASE; SUBSTRATE RECOGNITION; CALORIMETRY, HYDROLASE/HYDROLASE SUBSTRATE COMPLEX 
2nxl:A    (GLY52) to    (GLY94)  STRUCTURE OF HIV-1 PROTEASE D25N COMPLEXED WITH THE RT-RH ANALOGUE PEPTIDE GLY-ALA-GLU-VAL-PHE*TYR-VAL-ASP-GLY-ALA  |   PEPTIDE DESIGN; MOLECULAR DYNAMICS; HIV PROTEASE; SUBSTRATE RECOGNITION; CALORIMETRY, HYDROLASE/HYDROLASE SUBSTRATE COMPLEX 
2nxm:B    (LYS45) to    (GLY94)  STRUCTURE OF HIV-1 PROTEASE D25N COMPLEXED WITH THE RT-RH ANALOGUE PEPTIDE GLY-ALA-GLN-THR-PHE*TYR-VAL-ASP-GLY-ALA  |   PEPTIDE DESIGN; MOLECULAR DYNAMICS; HIV PROTEASE; SUBSTRATE RECOGNITION; CALORIMETRY, HYDROLASE/HYDROLASE SUBSTRATE COMPLEX 
2z4o:A    (LYS45) to    (GLY94)  WILD TYPE HIV-1 PROTEASE WITH POTENT ANTIVIRAL INHIBITOR GRL-98065  |   HIV-1, WILD TYPE PROTEASE, PROTEASE INHIBITOR, HYDROLASE 
3k4v:A    (LYS45) to    (GLY94)  NEW CRYSTAL FORM OF HIV-1 PROTEASE/SAQUINAVIR STRUCTURE REVEALS CARBAMYLATION OF N-TERMINAL PROLINE  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX, CARBAMYLATION, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, 
5cok:A    (LYS45) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-0476  |   GRL-0476, HIV-1 PROTEASE, PROTEASE-INHIBITOR, DARUNAVIR, TP-THF, NONPEPTIDIC, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5cok:B    (LYS45) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-0476  |   GRL-0476, HIV-1 PROTEASE, PROTEASE-INHIBITOR, DARUNAVIR, TP-THF, NONPEPTIDIC, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5con:A    (LYS45) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-015  |   GRL-015, HIV-1 PROTEASE, PROTEASE-INHIBITOR, DARUNAVIR, TP-THF, NONPEPTIDIC, HYDROXYL, O-METHOXY., HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5con:B    (LYS45) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-015  |   GRL-015, HIV-1 PROTEASE, PROTEASE-INHIBITOR, DARUNAVIR, TP-THF, NONPEPTIDIC, HYDROXYL, O-METHOXY., HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5coo:A    (LYS45) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-085  |   GRL-085, HIV-1 PROTEASE, PROTEASE-INHIBITOR, DARUNAVIR, TP-THF, NONPEPTIDIC, HYDROXYL, O-METHOXY., HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5coo:B    (LYS45) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-085  |   GRL-085, HIV-1 PROTEASE, PROTEASE-INHIBITOR, DARUNAVIR, TP-THF, NONPEPTIDIC, HYDROXYL, O-METHOXY., HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5cop:A    (LYS45) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-097  |   GRL-097, HIV-1 PROTEASE, PROTEASE-INHIBITOR, DARUNAVIR, TP-THF, NONPEPTIDIC, HYDROXYL, O-METHOXY., HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5cop:B    (LYS45) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-097  |   GRL-097, HIV-1 PROTEASE, PROTEASE-INHIBITOR, DARUNAVIR, TP-THF, NONPEPTIDIC, HYDROXYL, O-METHOXY., HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2o40:A   (PRO148) to   (GLY198)  CRYSTAL STRUCTURE OF A CHEMICALLY SYNTHESIZED 203 AMINO ACID 'COVALENT DIMER' HIV-1 PROTEASE MOLECULE  |   BETA-TURN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2o4k:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K) IN COMPLEX WITH ATAZANAVIR  |   PROTEASE COMPLEX, VIRAL PROTEIN 
2o4p:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K) IN COMPLEX WITH TIPRANAVIR  |   PROTEASE, VIRAL PROTEIN 
2o4s:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K) IN COMPLEX WITH LOPINAVIR  |   PROTEASE, VIRAL PROTEIN 
1lv1:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF THE NON-ACTIVE SITE MUTANT OF TETHERED HIV-1 PROTEASE TO 2.1A RESOLUTION  |   BETA-RIBBON FLAP, HYDROLASE 
1xl5:A    (ARG41) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH AMIDHYROXYSULFONE  |   ASPARTYL PROTEASE, HIV PROTEASE, AMIDHYDROXYSULFONE INHIBITOR, HYDROLASE 
4a6b:B   (GLY152) to   (GLY194)  STEREOSELECTIVE SYNTHESIS, X-RAY ANALYSIS, AND BIOLOGICAL EVALUATION OF A NEW CLASS OF LACTAM BASED HIV-1 PROTEASE INHIBITORS  |   HYDROLASE, GAMMA-BUTYROL-LACTAM 
1m0b:B   (LYS145) to   (GLY194)  HIV-1 PROTEASE IN COMPLEX WITH AN ETHYLENEAMINE INHIBITOR  |   HIV PROTEASE, PEPTIDOMIMETICS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2zga:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH A DIMETHYLALLYL DECORATED PYRROLIDINE BASED INHIBITOR (HEXAGONAL SPACE GROUP)  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3kdb:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, L33I, L63I) IN COMPLEX WITH KNI-10006  |   VIRAL PROTEIN, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3kf0:A    (LYS45) to    (GLY94)  HIV PROTEASE WITH FRAGMENT 4D9 BOUND  |   PROTEASE, TL-3 INHIBITOR, FRAGMENT HIT, ASPARTYL PROTEASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
3kfr:B    (GLY52) to    (GLY94)  HIV PROTEASE (PR) DIMER WITH INHIBITOR TL-3 BOUND AND FRAGMENT 1F1 IN THE OUTSIDE/TOP OF FLAP  |   HIV-1, PROTEASE, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1met:A    (LYS45) to    (GLY94)  HIV-1 MUTANT (V82F) PROTEASE COMPLEXED WITH DMP323  |   HYDROLASE, ACID PROTEINASE, ASPARTYL PROTEASE 
1met:B    (LYS45) to    (GLY94)  HIV-1 MUTANT (V82F) PROTEASE COMPLEXED WITH DMP323  |   HYDROLASE, ACID PROTEINASE, ASPARTYL PROTEASE 
2zye:A    (GLY52) to    (GLY94)  STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH POTENT INHIBITOR KNI-272 DETERMINED BY NEUTRON CRYSTALLOGRAPHY  |   HIV-1 PROTEASE, ACID PROTEASE, HOMODIMER, HYDROLASE, MULTIFUNCTIONAL ENZYME, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2zye:B   (GLY152) to   (GLY194)  STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH POTENT INHIBITOR KNI-272 DETERMINED BY NEUTRON CRYSTALLOGRAPHY  |   HIV-1 PROTEASE, ACID PROTEASE, HOMODIMER, HYDROLASE, MULTIFUNCTIONAL ENZYME, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1mrw:B    (PRO44) to    (GLY94)  STRUCTURE OF HIV PROTEASE (MUTANT Q7K L33I L63I) COMPLEXED WITH KNI- 577  |   HIV, KNI-577, PROTEASE, DRUG TARGET, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1msn:A    (LYS45) to    (GLY94)  THE HIV PROTEASE (MUTANT Q7K L33I L63I V82F I84V) COMPLEXED WITH KNI- 764 (AN INHIBITOR)  |   HIV, KNI-764, PROTEASE, DRUG TARGET, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1msm:A    (GLY40) to    (GLY94)  THE HIV PROTEASE (MUTANT Q7K L33I L63I) COMPLEXED WITH KNI-764 (AN INHIBITOR)  |   HIV, KNI-764, PROTEASE, DRUG TARGET, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1mt7:B    (GLY52) to    (GLY94)  VIABILITY OF A DRUG-RESISTANT HIV-1 PROTEASE MUTANT: STRUCTURAL INSIGHTS FOR BETTER ANTIVIRAL THERAPY  |   MATRIX, CAPSID, GAG CLEAVAGE, DRUG RESISTANCE, SUBSTRATE RECOGNITION, HYDROLASE/HYDROLASE INHIBITOR COMPLEX 
3kt2:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF N88D MUTANT HIV-1 PROTEASE  |   DRUG RESISTANT MUTATION, N88D, NELFINAVIR, HIV-1 PROTEASE, HYDROLASE, PROTEASE 
3kt2:A  (GLY1052) to  (GLY1094)  CRYSTAL STRUCTURE OF N88D MUTANT HIV-1 PROTEASE  |   DRUG RESISTANT MUTATION, N88D, NELFINAVIR, HIV-1 PROTEASE, HYDROLASE, PROTEASE 
3kt5:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF N88S MUTANT HIV-1 PROTEASE  |   DRUG RESISTANT, MUTATION, HIV-1 PROTEASE, N88S, NELFINAVIR, HYDROLASE, PROTEASE 
1n49:A    (GLY40) to    (GLY94)  VIABILITY OF A DRUG-RESISTANT HIV-1 PROTEASE VARIANT: STRUCTURAL INSIGHTS FOR BETTER ANTI-VIRAL THERAPY  |   HIV-1 PROTEASE, DRUG RESISTANCE, SUBSTRATE RECOGNITION, INHIBITOR BINDING, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1n49:C    (GLY40) to    (GLY94)  VIABILITY OF A DRUG-RESISTANT HIV-1 PROTEASE VARIANT: STRUCTURAL INSIGHTS FOR BETTER ANTI-VIRAL THERAPY  |   HIV-1 PROTEASE, DRUG RESISTANCE, SUBSTRATE RECOGNITION, INHIBITOR BINDING, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4phv:A    (LYS45) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF THE HIV PROTEASE COMPLEX WITH L- 700,417, AN INHIBITOR WITH PSEUDO C2 SYMMETRY  |   HYDROLASE(ASPARTIC PROTEINASE) 
5dgu:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE INHIBITORS CONTAINING SUBSTITUTED FUSED-TETRAHYDROPYRANYL TETRAHYDROFURAN AS P2-LIGAND GRL-004-11A  |   HIV-1 PROTEASE, ENZYME, HYDROLASE, HYDROLASE INHIBITOR 
1yt9:A    (LYS45) to    (ILE93)  HIV PROTEASE WITH OXIMINOARYLSULFONAMIDE BOUND  |   HIV PROTEASE, OXIMINOARYLSULFONAMIDES, HYDROLASE 
1yth:B    (GLY40) to    (GLY94)  SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT  |   AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE, RNA- DIRECTED DNA POLYMERASE, HYDROLASE-PEPTIDE COMPLEX 
1z1h:B   (GLY152) to   (GLY194)  HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 3  |   MACROCYCLIC INHIBITORS, PEPTIDOMIMETIC INHIBITORS, HIV1 PROTEASE, HYDROLASE 
3aid:B    (GLY52) to    (GLY94)  A NEW CLASS OF HIV-1 PROTEASE INHIBITOR: THE CRYSTALLOGRAPHIC STRUCTURE, INHIBITION AND CHEMICAL SYNTHESIS OF AN AMINIMIDE PEPTIDE ISOSTERE  |   ASPARTYL PROTEASE, PROTEASE, HIV, PEPTIDE ISOSTERE INHIBITOR, DRUG DESIGN 
1zj7:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF A COMPLEX OF MUTANT HIV-1 PROTEASE (A71V, V82T, I84V) WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR BOC-PHE- PSI[S-CH(OH)CH2NH]-PHE-GLU-PHE-NH2  |   HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1zlf:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF A COMPLEX OF MUTANT HIV-1 PROTEASE (A71V, V82T, I84V) WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR  |   HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1zlf:B   (LYS145) to   (GLY194)  CRYSTAL STRUCTURE OF A COMPLEX OF MUTANT HIV-1 PROTEASE (A71V, V82T, I84V) WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR  |   HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4q1w:A    (GLY52) to    (GLY94)  MUTATIONS OUTSIDE THE ACTIVE SITE OF HIV-1 PROTEASE ALTER ENZYME STRUCTURE AND DYNAMIC ENSEMBLE OF THE ACTIVE SITE TO CONFER DRUG RESISTANCE  |   HIV-1 PROTEASE, AIDS, INHIBITOR COMPLEX, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4q1x:B    (LYS45) to    (GLY94)  MUTATIONS OUTSIDE THE ACTIVE SITE OF HIV-1 PROTEASE ALTER ENZYME STRUCTURE AND DYNAMIC ENSEMBLE OF THE ACTIVE SITE TO CONFER DRUG RESISTANCE  |   HIV-1 PROTEASE, AIDS, INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1zpa:A    (LYS45) to    (GLY94)  HIV PROTEASE WITH SCRIPPS AB-3 INHIBITOR  |   PROTEASE, RETROVIRAL, HYDROLASE 
4q5m:A    (LYS45) to    (GLY94)  D30N TETHERED HIV-1 PROTEASE DIMER/SAQUINAVIR COMPLEX  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4q5m:A  (LYS1045) to  (GLY1094)  D30N TETHERED HIV-1 PROTEASE DIMER/SAQUINAVIR COMPLEX  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1zsf:B   (LYS145) to   (GLY194)  CRYSTAL STRUCTURE OF COMPLEX OF A HYDROXYETHYLAMINE INHIBITOR WITH HIV-1 PROTEASE AT 2.0A RESOLUTION  |   HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1zsr:B   (LYS145) to   (GLY194)  CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE (BRU ISOLATE) WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR BOC-PHE-PSI[S-CH(OH) CH2NH]-PHE-GLU-PHE-NH2  |   HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1ztz:A    (PRO44) to    (GLY94)  CRYSTAL STRUCTURE OF HIV PROTEASE- METALLACARBORANE COMPLEX  |   RATIONAL DRUG DESIGN; HIV PROTEASE INHIBITORS; ASPARTIC PROTEASES; CARBORANES; METALLACARBORANES, HYDROLASE 
2a1e:A    (GLY40) to    (GLY94)  HIGH RESOLUTION STRUCTURE OF HIV-1 PR WITH TS-126  |   HIV PR, PEPTIDOMIMETIC INHIBITOR, STEREOISOMER, SCREENING A MIXTURE, HYDROLASE 
3lzu:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF A NELFINAVIR RESISTANT HIV-1 CRF01_AE PROTEASE VARIANT (N88S) IN COMPLEX WITH THE PROTEASE INHIBITOR DARUNAVIR.  |   HIV-1 PROTEASE, NON-B CLADES, CRF01_AE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, HYDROLASE 
3lzu:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF A NELFINAVIR RESISTANT HIV-1 CRF01_AE PROTEASE VARIANT (N88S) IN COMPLEX WITH THE PROTEASE INHIBITOR DARUNAVIR.  |   HIV-1 PROTEASE, NON-B CLADES, CRF01_AE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, HYDROLASE 
2a4f:A    (ARG41) to    (GLY94)  SYNTHESIS AND ACTIVITY OF N-AXYL AZACYCLIC UREA HIV-1 PROTEASE INHIBITORS WITH HIGH POTENCY AGAINST MULTIPLE DRUG RESISTANT VIRAL STRAINS.  |   HIV PROTEASE, AZA-CYCLIC UREA, HYDROLASE 
2a4f:B    (PRO44) to    (GLY94)  SYNTHESIS AND ACTIVITY OF N-AXYL AZACYCLIC UREA HIV-1 PROTEASE INHIBITORS WITH HIGH POTENCY AGAINST MULTIPLE DRUG RESISTANT VIRAL STRAINS.  |   HIV PROTEASE, AZA-CYCLIC UREA, HYDROLASE 
4qgi:A    (LYS45) to    (GLY94)  X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE VARIANT G48T/L89M IN COMPLEX WITH SAQUINAVIR  |   SAQUINAVIR, HIV PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3m9f:A    (ARG41) to    (GLY94)  HIV PROTEASE COMPLEXED WITH COMPOUND 10B  |   HIV, PROTEASE, TRANSFERASE 
4qj6:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (L449F)  |   CO-EVOLUTION, PROTEASE, HYDROLASE 
4qj6:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (L449F)  |   CO-EVOLUTION, PROTEASE, HYDROLASE 
4qj6:C    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (L449F)  |   CO-EVOLUTION, PROTEASE, HYDROLASE 
4qj6:D    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (L449F)  |   CO-EVOLUTION, PROTEASE, HYDROLASE 
4qj7:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (R452S)  |   CO-EVOLUTION, PROTEASE, HYDROLASE 
4qja:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (P453L)  |   CO-EVOLUTION, PROTEASE, HYDROLASE 
3mim:A    (LYS45) to    (GLY94)  X-RAY SNAPSHOT OF HIV-1 PROTEASE IN ACTION: OBSERVATION OF TETRAHEDRAL INTERMEDIATE AND ITS SIHB WITH CATALYTIC ASPARTATE  |   HIV-1 PROTEASE, SHORT IONIC HYDROGEN BOND, TETHERED DIMER, TETRAHEDRAL INTERMEDIATE, REVERSE TRANSCRIPTASE-RNASEH OLIGOPEPTIDE SUBSTRATE, REACTION MECHANISM, HYDROLASE 
3mim:B  (LYS1045) to  (GLY1094)  X-RAY SNAPSHOT OF HIV-1 PROTEASE IN ACTION: OBSERVATION OF TETRAHEDRAL INTERMEDIATE AND ITS SIHB WITH CATALYTIC ASPARTATE  |   HIV-1 PROTEASE, SHORT IONIC HYDROGEN BOND, TETHERED DIMER, TETRAHEDRAL INTERMEDIATE, REVERSE TRANSCRIPTASE-RNASEH OLIGOPEPTIDE SUBSTRATE, REACTION MECHANISM, HYDROLASE 
3bgb:A    (GLY40) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH A ISOBUTYL DECORATED OLIGOAMINE  |   PROTEIN-LIGAND COMPLEX, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER 
3bgc:A    (GLY40) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH A BENZYL DECORATED OLIGOAMINE  |   PROTEIN-LIGAND COMPLEX, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER 
3bhe:B    (GLY40) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH A THREE ARMED PYRROLIDINE DERIVATIVE  |   PROTEIN-LIGAND COMPLEX, HYDROLASE 
3mws:B   (GLY152) to   (GLY194)  CRYSTAL STRUCTURE OF GROUP N HIV-1 PROTEASE  |   HIV-1, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3mxe:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE INHIBITOR, KC32 COMPLEXED WITH WILD-TYPE PROTEASE  |   DRUG DESIGN, PROTEASE INHIBITORS, HIV PROTEASE, HYDROLASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
3mxe:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE INHIBITOR, KC32 COMPLEXED WITH WILD-TYPE PROTEASE  |   DRUG DESIGN, PROTEASE INHIBITORS, HIV PROTEASE, HYDROLASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
3bvb:A    (LYS45) to    (GLY94)  CYSTAL STRUCTURE OF HIV-1 ACTIVE SITE MUTANT D25N AND INHIBITOR DARUNAVIR  |   DRUG RESISTANCE; HIV-1; D25N, MUTANT, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, DNA INTEGRATION, DNA RECOMBINATION, DNA- DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC-FINGER 
3bxr:B   (GLY152) to   (GLY194)  CRYSTAL STRUCTURES OF HIGHLY CONSTRAINED SUBSTRATE AND HYDROLYSIS PRODUCTS BOUND TO HIV-1 PROTEASE. IMPLICATIONS FOR CATALYTIC MECHANISM  |   HIV PROTEASE, HIVPR, SUBSTRATE, PRODUCT, MECHANISM, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER 
3bxs:B   (GLY152) to   (GLY194)  CRYSTAL STRUCTURES OF HIGHLY CONSTRAINED SUBSTRATE AND HYDROLYSIS PRODUCTS BOUND TO HIV-1 PROTEASE. IMPLICATIONS FOR CATALYTIC MECHANISM  |   HIV PROTEASE, HIVPR, SUBSTRATE, PRODUCT, MECHANISM, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER 
3n3i:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF G48V/C95F TETHERED HIV-1 PROTEASE/SAQUINAVIR COMPLEX  |   HIV-1 PROTEASE, SAQUINAVIR, DRUG RESISTANCE, TETHERED-DIMER, FUSION PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5fiv:A    (GLY52) to   (ASN111)  STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITH AN EFFICIENT INHIBITOR OF FIV PR  |   FIV PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3ndt:A    (LYS46) to    (GLY95)  HIV-1 PROTEASE SAQUINAVIR:RITONAVIR 1:1 COMPLEX STRUCTURE  |   HYDROLASE, AIDS, ASPARTYL PROTEASE, CARBAMYLATION, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
3ndt:B    (LYS46) to    (GLY95)  HIV-1 PROTEASE SAQUINAVIR:RITONAVIR 1:1 COMPLEX STRUCTURE  |   HYDROLASE, AIDS, ASPARTYL PROTEASE, CARBAMYLATION, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
3ndt:D    (LYS45) to    (GLY94)  HIV-1 PROTEASE SAQUINAVIR:RITONAVIR 1:1 COMPLEX STRUCTURE  |   HYDROLASE, AIDS, ASPARTYL PROTEASE, CARBAMYLATION, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
3ndx:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE SAQUINAVIR:RITONAVIR 1:50 COMPLEX STRUCTURE  |   HIV-1 PROTEASE, HYDROLASE, AIDS, ASPARTYL PROTEASE, SAQUINAVIR, CARBAMYLATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3ckt:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH A DIMETHYLALLYL DECORATED PYRROLIDINE BASED INHIBITOR (ORTHOROMBIC SPACE GROUP)  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3nu5:A    (ARG41) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT I50V WITH ANTIVIRAL DRUG AMPRENAVIR  |   ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3nu5:B   (LYS145) to   (GLY194)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT I50V WITH ANTIVIRAL DRUG AMPRENAVIR  |   ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3nu6:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT I54M WITH ANTIVIRAL DRUG AMPRENAVIR  |   ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, AMPRENAVIR, CONFORMATIONAL CHANGE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3nu9:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT I84V WITH ANTIVIRAL DRUG AMPRENAVIR  |   ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3nuj:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT I54V WITH ANTIVIRAL DRUG AMPRENAVIR  |   ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3nuj:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT I54V WITH ANTIVIRAL DRUG AMPRENAVIR  |   ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3nwq:A    (LYS45) to    (GLY94)  X-RAY STRUCTURE OF ESTER CHEMICAL ANALOGUE [O-ILE50,O-ILE50']HIV-1 PROTEASE COMPLEXED WITH MVT-101  |   BETA-BARREL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3nwx:A    (PRO44) to    (GLY94)  X-RAY STRUCTURE OF ESTER CHEMICAL ANALOGUE [O-ILE50,O-ILE50']HIV-1 PROTEASE COMPLEXED WITH KVS-1 INHIBITOR  |   BETA-BARREL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3nwx:B    (GLY52) to    (GLY94)  X-RAY STRUCTURE OF ESTER CHEMICAL ANALOGUE [O-ILE50,O-ILE50']HIV-1 PROTEASE COMPLEXED WITH KVS-1 INHIBITOR  |   BETA-BARREL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3nxe:A   (LYS149) to   (GLY198)  X-RAY STRUCTURE OF ESTER CHEMICAL ANALOGUE 'COVALENT DIMER' [ILE50,O- ILE50']HIV-1 PROTEASE COMPLEXED WITH MVT-101 INHIBITOR  |   BETA-BARREL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3nxn:A    (PRO44) to    (GLY94)  X-RAY STRUCTURE OF ESTER CHEMICAL ANALOGUE 'COVALENT DIMER' [ILE50,O- ILE50']HIV-1 PROTEASE COMPLEXED WITH KVS-1 INHIBITOR  |   BETA-BARREL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3nxn:A   (GLY156) to   (GLY198)  X-RAY STRUCTURE OF ESTER CHEMICAL ANALOGUE 'COVALENT DIMER' [ILE50,O- ILE50']HIV-1 PROTEASE COMPLEXED WITH KVS-1 INHIBITOR  |   BETA-BARREL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4rvx:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH NON-PEPTIDIC INHIBITOR, GRL079  |   HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, HIV-1 PROTEASE- INHIBITOR COMPLEX, GRL079, NON-PEPTIDIC PROTEASE INHIBITOR 
4rvx:C    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH NON-PEPTIDIC INHIBITOR, GRL079  |   HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, HIV-1 PROTEASE- INHIBITOR COMPLEX, GRL079, NON-PEPTIDIC PROTEASE INHIBITOR 
4rvx:D    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH NON-PEPTIDIC INHIBITOR, GRL079  |   HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, HIV-1 PROTEASE- INHIBITOR COMPLEX, GRL079, NON-PEPTIDIC PROTEASE INHIBITOR 
3cyw:A    (LYS45) to    (GLY94)  EFFECT OF FLAP MUTATIONS ON STRUCTURE OF HIV-1 PROTEASE AND INHIBITION BY SAQUINAVIR AND DARUNAVIR  |   DRUG RESISTANCE; HIV-1, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC-FINGER 
3cyx:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 MUTANT I50V AND INHIBITOR SAQUINAVIRA  |   DRUG RESISTANCE; HIV-1, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4coe:A    (LYS45) to    (GLY94)  MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL  |   HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, ENZYME 
3d1x:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 MUTANT I54M AND INHIBITOR SAQUINAVIR  |   DRUG RESISTANCE, HIV-1, I54M, FLAP MUTANT, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, VIRAL NUCLEOPROTEIN 
3d1z:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 MUTANT I54M AND INHIBITOR DARUNAVIR  |   DRUG RESISTANCE; HIV-1, FLAP MUTANT, I54M, DARUNAVIR, HYDROLASE 
4cpr:A    (LYS45) to    (GLY94)  MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL  |   HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN 
4cps:A    (LYS45) to    (GLY94)  MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL  |   HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN 
4cpt:A    (LYS45) to    (GLY94)  MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL  |   HYDROLASE, HIV-1 PROTEASE, INHIBITOR, RATIONAL DRUG DESIGN, ENZYME 
4cpu:A    (LYS45) to    (GLY94)  MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL  |   HYDROLASE, HIV-1 PROTEASE, INHIBITOR, RATIONAL DRUG DESIGN 
4cpw:A    (LYS45) to    (GLY94)  MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL  |   HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN 
3o99:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD13  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3o9a:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD14  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3o9b:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD25  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3o9d:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD19  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3o9f:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD27  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3o9f:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD27  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3o9g:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF53  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3o9i:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF61  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3o9i:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF61  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3dcr:A    (GLY52) to    (GLY94)  X-RAY STRUCTURE OF HIV-1 PROTEASE AND HYDRATED FORM OF KETOMETHYLENE ISOSTERE INHIBITOR  |   HIV-1 PROTEASE, HOMODIMER, BETA-TURN, BETA-STRAND, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3djk:A    (LYS45) to    (GLY94)  WILD TYPE HIV-1 PROTEASE WITH POTENT ANTIVIRAL INHIBITOR GRL-0255A  |   HIV-1, WILD TYPE PROTEASE, PROTEASE INHIBITOR, HYDROLASE, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, LIPOPROTEIN, MAGNESIUM, METAL- BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER 
3dk1:A    (LYS45) to    (GLY94)  WILD TYPE HIV-1 PROTEASE WITH POTENT ANTIVIRAL INHIBITOR GRL-0105A  |   HIV-1, WILD TYPE PROTEASE, PROTEASE INHIBITOR, HYDROLASE, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, LIPOPROTEIN, MAGNESIUM, METAL- BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER 
4tvg:A    (LYS45) to    (GLY94)  HIV PROTEASE (PR) DIMER IN CLOSED FORM WITH PEPSTATIN IN ACTIVE SITE AND FRAGMENT AK-2097 IN THE OUTSIDE/TOP OF FLAP  |   APO PROTEASE, ALLOSTERY, FRAGMENT BINDING 
3dox:A    (LYS45) to    (GLY94)  X-RAY STRUCTURE OF HIV-1 PROTEASE IN SITU PRODUCT COMPLEX  |   HIV-1 PROTEASE; TRANSITION STATE; REACTION INTERMEDIATE; CATALYSIS; INHIBITOR; X-RAY CRYSTALLOGRAPHY, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HOST-VIRUS INTERACTION, HYDROLASE, LIPOPROTEIN, MAGNESIUM, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER 
3dox:A  (LYS1045) to  (GLY1094)  X-RAY STRUCTURE OF HIV-1 PROTEASE IN SITU PRODUCT COMPLEX  |   HIV-1 PROTEASE; TRANSITION STATE; REACTION INTERMEDIATE; CATALYSIS; INHIBITOR; X-RAY CRYSTALLOGRAPHY, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HOST-VIRUS INTERACTION, HYDROLASE, LIPOPROTEIN, MAGNESIUM, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER 
3oxv:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 I50V, A71 PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR AMPRENAVIR.  |   HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, DRUG RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3oxv:D    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 I50V, A71 PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR AMPRENAVIR.  |   HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, DRUG RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3oxv:C    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 I50V, A71 PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR AMPRENAVIR.  |   HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, DRUG RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3oxw:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 I50V, A71V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR DARUNAVIR  |   HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, DRUG RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3oxw:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 I50V, A71V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR DARUNAVIR  |   HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, DRUG RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3oxx:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 I50V, A71V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR ATAZANAVIR  |   HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3oxx:C    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 I50V, A71V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR ATAZANAVIR  |   HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3oy4:A    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 L76V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR DARUNAVIR.  |   HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4djp:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH MKP73  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4djq:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH MKP86  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4djr:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH MKP97  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4djr:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH MKP97  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4u7q:A    (PRO44) to    (GLY94)  STRUCTURE OF WILD-TYPE HIV PROTEASE IN COMPLEX WITH PHOTOSENSITIVE INHIBITOR PDI-6  |   HIV-1, VIRAL PROTEASE, ASPARTIC PROTEASE, INHIBITION, HYDROLASE 
4u7q:B    (PRO44) to    (GLY94)  STRUCTURE OF WILD-TYPE HIV PROTEASE IN COMPLEX WITH PHOTOSENSITIVE INHIBITOR PDI-6  |   HIV-1, VIRAL PROTEASE, ASPARTIC PROTEASE, INHIBITION, HYDROLASE 
4u8w:A    (LYS45) to    (GLY94)  HIV-1 WILD TYPE PROTEASE WITH GRL-050-10A (A GEM-DIFLUORO-BIS- TETRAHYDROFURAN AS P2-LIGAND)  |   HIV-1 PROTEASE INHIBITOR, MULTIDRUG-RESISTANT HIV-1 STRAINS, BLOOD- BRAIN-BARRIER, FLUORO-BIS-THF, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4dqb:A    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH DRV  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4dqe:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF (G16C/L38C) HIV-1 PROTEASE IN COMPLEX WITH DRV  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4dqe:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF (G16C/L38C) HIV-1 PROTEASE IN COMPLEX WITH DRV  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4dqg:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF APO(G16C/L38C) HIV-1 PROTEASE  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5hvp:A    (LYS45) to    (GLY94)  CRYSTALLOGRAPHIC ANALYSIS OF A COMPLEX BETWEEN HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE AND ACETYL-PEPSTATIN AT 2.0-ANGSTROMS RESOLUTION  |   ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4upj:B    (ASN41) to    (GLY94)  HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 PROTEASE MUTANT WITH LYS 57 REPLACED BY LEU (K57L) COMPLEX WITH U097410 [4-HYDROXY-3-[1-[3- [[[[(TERT-BUTYLOXYCARBONYL) AMINOMETHYL]CARBONYL]AMINO]PHENYL]PROPYL]COUMARIN  |   HYDROLASE (ACID PROTEASE) 
3psu:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH AN ISOBUTYL DECORATED OLIGOAMINE (SYMMETRIC BINDING MODE)  |   ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3pwr:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE MUTANT L76V COMPLEXED WITH SAQUINAVIR  |   HIV-1, PROTEASE, MUTATION L76V, SAQUINAVIR, HYDROLASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
4ej8:A    (PRO44) to    (GLY94)  APO HIV PROTEASE (PR) DIMER IN CLOSED FORM WITH FRAGMENT 1F1 IN THE OUTSIDE/TOP OF FLAP  |   APO PROTEASE, ALLOSTERY, FRAGMENT BINDING, CLOSED FORM, HYDROLASE 
4ej8:B    (GLY52) to    (GLY94)  APO HIV PROTEASE (PR) DIMER IN CLOSED FORM WITH FRAGMENT 1F1 IN THE OUTSIDE/TOP OF FLAP  |   APO PROTEASE, ALLOSTERY, FRAGMENT BINDING, CLOSED FORM, HYDROLASE 
4ejd:A    (LYS45) to    (GLY94)  HIV PROTEASE (PR) DIMER IN CLOSED FORM WITH PEPSTATIN IN ACTIVE SITE AND FRAGMENT 1F1 IN THE OUTSIDE/TOP OF FLAP  |   APO PROTEASE, ALLOSTERY, FRAGMENT BINDING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4ejd:B    (LYS45) to    (GLY94)  HIV PROTEASE (PR) DIMER IN CLOSED FORM WITH PEPSTATIN IN ACTIVE SITE AND FRAGMENT 1F1 IN THE OUTSIDE/TOP OF FLAP  |   APO PROTEASE, ALLOSTERY, FRAGMENT BINDING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4ejk:A    (LYS45) to    (GLY94)  HIV PROTEASE (PR) DIMER IN CLOSED FORM WITH PEPSTATIN IN ACTIVE SITE AND FRAGMENT 1F1-N IN THE OUTSIDE/TOP OF FLAP  |   APO PROTEASE, ALLOSTERY, FRAGMENT BINDING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4ep2:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE SINGLE CHAIN WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH THE SUBSTRATE RT-RH  |   HIV-1 PROTEASE, SPECIFICITY DESIGN, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE SUBSTRATE COMPLEX 
5ivr:A    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH METHYL N-[(1S)-1-[[2- [(3S)-3-[(4-AMINOPHENYL)METHYLAMINO]-4-HYDROXY- BUTYL]PHENYL]CARBAMOYL]-2,2-DIPHENYL-ETHYL]CARBAMATE  |   HIV, PROTEASE, HYDROLASE-INHIBITOR COMPLEX 
5ivs:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH METHYL N-[(1S)-1- BENZHYDRYL-2-[2-[2-[(2R,5S)-5-(BENZYLCARBAMOYLOXYMETHYL)MORPHOLIN-2- YL]ETHYL]ANILINO]-2-OXO-ETHYL]CARBAMATE  |   HIV, PROTEASE, HYDROLASE-INHIBITOR COMPLEX 
5ivt:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH [(1S)-1-[(S)-(4- CHLOROPHENYL)-(3,5-DIFLUOROPHENYL)METHYL]-2-[[5-FLUORO-4-[2-[(2R,5S)- 5-(2,2,2-TRIFLUOROETHYLCARBAMOYLOXYMETHYL)MORPHOLIN-4-IUM-2- YL]ETHYL]PYRIDIN-1-IUM-3-YL]AMINO]-2-OXO-ETHYL]AMMONIUM  |   HIV, PROTEASE, HYDROLASE-INHIBITOR COMPLEX 
3qbf:B    (PRO44) to    (GLY94)  HIV-1 PROTEASE (MUTANT Q7K L33I L63I) IN COMPLEX WITH A THREE-ARMED PYRROLIDINE-BASED INHIBITOR  |   ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3qih:B    (PRO44) to    (GLY94)  HIV-1 PROTEASE (MUTANT Q7K L33I L63I) IN COMPLEX WITH A NOVEL INHIBITOR  |   ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4f74:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF ACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE N TERMINAL PRODUCT OF THE SUBSTRATE MA-CA.  |   HIV-1 PROTEASE, SUBSTRATE COMPLEX, AIDS, PRODUCT COMPLEX, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE PRODUCT COMPLEX 
4f75:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF ACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE N TERMINAL PRODUCT OF THE SUBSTRATE RH-IN  |   HIV-1 PROTEASE, SUBSTRATE COMPLEX, AIDS, PRODUCT COMPLEX, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE PRODUCT COMPLEX 
4f75:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF ACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE N TERMINAL PRODUCT OF THE SUBSTRATE RH-IN  |   HIV-1 PROTEASE, SUBSTRATE COMPLEX, AIDS, PRODUCT COMPLEX, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE PRODUCT COMPLEX 
4f76:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF THE ACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE PRODUCTS OF P1-P6 SUBSTRATE  |   HIV-1 PROTEASE, SUBSTRATE COMPLEX, AIDS, PRODUCT COMPLEX, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE PRODUCT COMPLEX 
4f76:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF THE ACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE PRODUCTS OF P1-P6 SUBSTRATE  |   HIV-1 PROTEASE, SUBSTRATE COMPLEX, AIDS, PRODUCT COMPLEX, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE PRODUCT COMPLEX 
4faf:A    (LYS45) to    (GLY94)  SUBSTRATE CA/P2 IN COMPLEX WITH A HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE VARIANT  |   PROTEASE, VIRAL PROTEIN 
3qn8:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE (MUTANT Q7K L33I L63I) IN COMPLEX WITH A NOVEL INHIBITOR  |   ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3qn8:B    (PRO44) to    (GLY94)  HIV-1 PROTEASE (MUTANT Q7K L33I L63I) IN COMPLEX WITH A NOVEL INHIBITOR  |   ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3qp0:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE (MUTANT Q7K L33I L63I) IN COMPLEX WITH A NOVEL INHIBITOR  |   ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3qrm:A    (ARG41) to    (GLY94)  HIV-1 PROTEASE (MUTANT Q7K L33I L63I) IN COMPLEX WITH A THREE-ARMED PYRROLIDINE-BASED INHIBITOR  |   ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3qro:A    (ARG41) to    (GLY94)  HIV-1 PROTEASE (MUTANT Q7K L33I L63I) IN COMPLEX WITH A THREE-ARMED PYRROLIDINE-BASED INHIBITOR  |   ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4fe6:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH AN ENAMINO- OXINDOLE INHIBITOR  |   HYDROLASE-INHIBITOR COMPLEX 
4fiv:A    (GLY52) to   (ASN111)  FIV PROTEASE COMPLEXED WITH AN INHIBITOR LP-130  |   ASPARTIC PROTEASE, FIV, RETROPEPSIN, RETROVIRUS, CAT 
5jfp:A    (LYS45) to    (GLY94)  HIV-1 WILD TYPE PROTEASE WITH GRL-097-13A (A ADAMANTANE P1-LIGAND WITH BIS-THF IN P2 AND ISOBUTYLAMINE IN P1')  |   ADAMANTANE, HIV-1 PROTEASE INHIBITOR GRL-097-13A, DARUNAVIR, MULTIDRUG-RESISTANT, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5jfu:A    (LYS45) to    (GLY94)  HIV-1 WILD TYPE PROTEASE WITH GRL-007-14A (A ADAMANTANE P1-LIGAND WITH BIS-THF IN P2 AND BENZYLAMINE IN P1')  |   ADAMANTANE, HIV-1 PROTEASE INHIBITOR GRL-007-14A, DARUNAVIR, MULTIDRUG-RESISTANT, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5jg1:A    (LYS45) to    (GLY94)  HIV-1 WILD TYPE PROTEASE WITH GRL-031-14A (A ADAMANTANE P1-LIGAND WITH TETRAHYDROPYRANO-TETRAHYDROFURAN IN P2 AND ISOBUTYLAMINE IN P1')  |   ADAMANTANE, HIV-1 PROTEASE INHIBITOR GRL-031-14A, DARUNAVIR, MULTIDRUG-RESISTANT, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5jg1:B    (PRO44) to    (GLY94)  HIV-1 WILD TYPE PROTEASE WITH GRL-031-14A (A ADAMANTANE P1-LIGAND WITH TETRAHYDROPYRANO-TETRAHYDROFURAN IN P2 AND ISOBUTYLAMINE IN P1')  |   ADAMANTANE, HIV-1 PROTEASE INHIBITOR GRL-031-14A, DARUNAVIR, MULTIDRUG-RESISTANT, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5kqx:A    (LYS45) to    (GLY94)  PROTEASE E35D-SQV  |   HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE-HUDROLASE INHIBITOR COMPLEX 
5kqy:A    (LYS45) to    (GLY94)  PROTEASE E35D-DRV  |   HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5kqy:B    (PRO44) to    (GLY94)  PROTEASE E35D-DRV  |   HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5kr0:A    (LYS45) to    (GLY94)  PROTEASE E35D-APV  |   HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5kr1:A    (GLY40) to    (GLY94)  PROTEASE PR5-DRV  |   HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5kr2:A    (PRO44) to    (GLY94)  PROTEASE PR5-SQV  |   HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5kr2:B    (GLY52) to    (GLY94)  PROTEASE PR5-SQV  |   HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5kr2:C    (LYS45) to    (GLY94)  PROTEASE PR5-SQV  |   HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5kr2:D    (LYS45) to    (GLY94)  PROTEASE PR5-SQV  |   HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
9hvp:B    (LYS45) to    (GLY94)  DESIGN, ACTIVITY AND 2.8 ANGSTROMS CRYSTAL STRUCTURE OF A C2 SYMMETRIC INHIBITOR COMPLEXED TO HIV-1 PROTEASE  |   ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2p3a:A    (ARG45) to    (GLY94)  CRYSTAL STRUCTURE OF THE MULTI-DRUG RESISTANT MUTANT SUBTYPE B HIV PROTEASE COMPLEXED WITH TL-3 INHIBITOR  |   MULTI-DRUG RESISTANT MUTANT SUBTYPE B HIV PROTEASE, TL-3 INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2p3a:B    (ARG45) to    (GLY94)  CRYSTAL STRUCTURE OF THE MULTI-DRUG RESISTANT MUTANT SUBTYPE B HIV PROTEASE COMPLEXED WITH TL-3 INHIBITOR  |   MULTI-DRUG RESISTANT MUTANT SUBTYPE B HIV PROTEASE, TL-3 INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1bdr:A    (LYS45) to    (GLY94)  HIV-1 (2: 31, 33-37) PROTEASE COMPLEXED WITH INHIBITOR SB203386  |   HYDROLASE, AIDS, POLYPROTEIN, ASPARTYL PROTEASE, ACID PROTEASE, HYDROXYETHYLENE ISOSTERE INHIBITOR, SUBSTRATE ANALOGUE INHIBITOR 
3s53:B    (GLY52) to    (GLY94)  HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH ANTIVIRAL DRUG DARUNAVIR IN SPACE GROUP P212121  |   DARUNAVIR,HIV/AIDS, DRUG RESISTANCE, ASPARTIC PROTEASE, MOLECULAR RECOGNITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1bve:B    (GLY40) to    (GLY94)  HIV-1 PROTEASE-DMP323 COMPLEX IN SOLUTION, NMR, 28 STRUCTURES  |   AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE, RNA-DIRECTED DNA POLYMERASE 
1bwa:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE (V82F/I84V) DOUBLE MUTANT COMPLEXED WITH XV638 OF DUPONT PHARMACEUTICALS  |   HIV-1 PROTEASE, HYDROLASE 
3sa3:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AG23  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3sa3:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AG23  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3sa9:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF68  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3sa9:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF68  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1c6x:A    (ILE47) to    (GLY94)  ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.  |   HYDROLASE 
1c6x:B   (LYS245) to   (GLY294)  ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.  |   HYDROLASE 
1c70:A    (GLY52) to    (GLY94)  ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.  |   HYDROLASE 
3fsm:A   (LYS149) to   (GLY198)  CRYSTAL STRUCTURE OF A CHEMICALLY SYNTHESIZED 203 AMINO ACID 'COVALENT DIMER' [L-ALA51,D-ALA51'] HIV-1 PROTEASE MOLECULE  |   ASYMMETRIC DIMER, COVALENT DIMER, BETA-SHEET, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3st5:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE WITH C3-SUBSTITUTED HEXAHYDROCYCLOPENTAFURANYL URETHANE AS P2-LIGAND, GRL-0489A  |   ASPARTIC ACID PROTEASE, HIV-1 PROTEASE INHIBITOR GRL-0489A, C3- SUBSTITUTED HEXAHYDROCYCLOPENTAFURANYL URETHANE AS P2-LIGANDS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1dmp:A    (GLY40) to    (GLY94)  STRUCTURE OF HIV-1 PROTEASE COMPLEX  |   AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ACID PROTEASE, RNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, ASPARTYL PROTEINASE 
1dmp:B    (LYS45) to    (GLY94)  STRUCTURE OF HIV-1 PROTEASE COMPLEX  |   AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ACID PROTEASE, RNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, ASPARTYL PROTEINASE 
3ggx:C    (LYS45) to    (GLY94)  HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS  |   HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE 
3ggx:D    (LYS45) to    (GLY94)  HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS  |   HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE 
3ggx:F    (GLY52) to    (GLY94)  HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS  |   HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE 
1ebz:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA388  |   DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX 
1ec2:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA428  |   DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX 
4jec:A    (GLY52) to    (GLY94)  JOINT NEUTRON AND X-RAY STRUCTURE OF PER-DEUTERATED HIV-1 PROTEASE IN COMPLEX WITH CLINICAL INHIBITOR AMPRENAVIR  |   PROTEASE, HYDROLYSIS, POLYPEPTIDES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4jec:B   (GLY140) to   (GLY194)  JOINT NEUTRON AND X-RAY STRUCTURE OF PER-DEUTERATED HIV-1 PROTEASE IN COMPLEX WITH CLINICAL INHIBITOR AMPRENAVIR  |   PROTEASE, HYDROLYSIS, POLYPEPTIDES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1qbs:B    (GLY52) to    (GLY94)  HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY  |   HYDROLASE (ACID PROTEINASE), ASPARTYL PROTEASE 
1fg8:C    (LYS45) to    (GLY94)  STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES  |   HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1fqx:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF THE COMPLEX OF HIV-1 PROTEASE WITH A PEPTIDOMIMETIC INHIBITOR  |   ASPARTYL PROTEASE, PROTEASE, HIV, PEPTIDOMIMETIC, INHIBITOR, DRUG DESIGN, HYDROXYETHYLAMINE ISOSTERE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1fqx:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF THE COMPLEX OF HIV-1 PROTEASE WITH A PEPTIDOMIMETIC INHIBITOR  |   ASPARTYL PROTEASE, PROTEASE, HIV, PEPTIDOMIMETIC, INHIBITOR, DRUG DESIGN, HYDROXYETHYLAMINE ISOSTERE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2f80:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE MUTANT D30N COMPLEXED WITH INHIBITOR TMC114  |   PROTEIN-INHIBITOR COMPLEX, HYDROLASE 
4z50:C    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20D25N WITH TUCKED FLAP  |   HIV-1 PROTEASE, HYDROLASE 
3hzc:A   (LYS149) to   (GLY198)  CRYSTAL STRUCTURE OF A CHEMICALLY SYNTHESIZED 203 AMINO ACID 'COVALENT DIMER' [GLY51;AIB51']HIV-1 PROTEASE MOLECULE COMPLEXED WITH MVT-101 REDUCED ISOSTERE INHIBITOR  |   ASYMMETRIC DIMER, COVALENT DIMER, BETA-SHEET, HYDROLASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
1gnm:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE MUTANT WITH VAL 82 REPLACED BY ASP (V82D) COMPLEXED WITH U89360E (INHIBITOR)  |   ASPARTIC PROTEASE, HIV, MUTANT, INHIBITOR, U-89360E, HYDROLASE (ACID PROTEASE) 
1sgu:A    (GLY40) to    (GLY94)  COMPARING THE ACCUMULATION OF ACTIVE SITE AND NON-ACTIVE SITE MUTATIONS IN THE HIV-1 PROTEASE  |   ACTIVE SITE MUTATIONS, NON-ACTIVE SITE MUTATIONS, INDINAVIR, HIV-1 PROTEASE, HYDROLASE 
1sh9:A    (LYS45) to    (GLY94)  COMPARING THE ACCUMULATION OF ACTIVE SITE AND NON-ACTIVE SITE MUTATIONS IN THE HIV-1 PROTEASE  |   HIV-1 PROTEASE, NON-ACTIVE SITE MUTATIONS, ACTIVE SITE MUTATIONS, RITONAVIR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3i2l:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF A CHEMICALLY SYNTHESIZED [ALLO-ILE50/50']HIV-1 PROTEASE MOLECULE COMPLEXED WITH MVT-101 REDUCED ISOSTERE INHIBITOR  |   BETA-SHEET, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3i8w:A    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF A METALLACARBORANE INHIBITOR BOUND TO HIV PROTEASE  |   INHIBITOR, COBALT BIS(1,2-DICARBOLLIDE), VIRAL RESISTANCE, ASPARTIC PROTEASE, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, CELL MEMBRANE, DNA INTEGRATION, DNA RECOMBINATION, DNA- DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC-FINGER, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
3vf7:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT L76V WITH NOVEL P1'-LIGANDS GRL-02031  |   PROTEASE INHIBITOR,P1'-LIGAND, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1t7j:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF INHIBITOR AMPRENAVIR IN COMPLEX WITH A MULTI-DRUG RESISTANT VARIANT OF HIV-1 PROTEASE (L63P/V82T/I84V)  |   HIV-1 PROTEASE, DRUG RESITANCE, THERMODYNAMICS, SUBSTRATE ENVELOPE, HYDROLASE 
1heg:E    (LYS45) to    (GLY94)  THE CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF HYDROXYETHYLENE- BASED INHIBITORS BOUND TO HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE SHOW THAT THE INHIBITORS ARE PRESENT IN TWO DISTINCT ORIENTATIONS  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX, ACID PROTEINASE 
2hb2:A    (LYS43) to    (GLY94)  STRUCTURE OF HIV PROTEASE 6X MUTANT IN APO FORM  |   HIV, PROTEASE, RETROVIRUS, ASPARTYL, HYDROLASE 
1hxb:A    (LYS45) to    (GLY94)  HIV-1 PROTEINASE COMPLEXED WITH RO 31-8959  |   HYDROLASE-HYDROLASE INHIBITOR COMPLEX, ASPARTYL PROTEASE 
2i4d:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF WT HIV-1 PROTEASE WITH GS-8373  |   HIV-1 PROTEASE, HYDROLASE 
1iiq:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR  |   HIV PROTEASE, PEPTIDOMIMETICS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4m8y:A    (PRO45) to    (GLY95)  GS-8374, A NOVEL PHOSPHONATE-CONTAINING INHIBITOR OF HIV-1 PROTEASE, EFFECTIVELY INHIBITS HIV PR MUTANTS WITH AMINO ACID INSERTIONS  |   HIV-1 PROTEASE, ASPARTIC PROTEASE, AMINO ACID INSERTION, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
2ien:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE WITH A POTENT NON-PEPTIDE INHIBITOR (UIC-94017)  |   HIV-1 PROTEASE, DIMER, INHIBITOR, UIC-94017, TMC114, DARUNAVIR, HYDROLASE 
1w5v:A    (GLY52) to    (GLY94)  HIV-1 PROTEASE IN COMPLEX WITH FLUORO SUBSTITUTED DIOL- BASED C2-SYMMETRIC INHIBITOR  |   HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE, DIMER, PROTEIN-INHIBITOR COMPLEX 
4njs:A    (ARG45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH NON-PEPTIDIC INHIBITOR, GRL008  |   MULTIDRUG-RESISTANCE, HIV-1 PROTEASE, NON-PEPTIDIC INHIBITOR, PROTEASE INHIBITOR, DARUNAVIR ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4njs:C    (ARG45) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH NON-PEPTIDIC INHIBITOR, GRL008  |   MULTIDRUG-RESISTANCE, HIV-1 PROTEASE, NON-PEPTIDIC INHIBITOR, PROTEASE INHIBITOR, DARUNAVIR ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1kj4:D    (LYS45) to    (GLY94)  SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES  |   MARIX-CAPSID, SUBSTRATE RECOGNITION, HYDROLASE 
1kjf:A    (GLY40) to    (GLY94)  SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES  |   P1-P6, SUBSTRATE RECOGNITION, HYDROLASE 
2nph:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV1 PROTEASE IN SITU PRODUCT COMPLEX  |   ANTI-PARALLEL BETA SHEET, HYDROLASE 
2nph:B  (GLY1052) to  (GLY1094)  CRYSTAL STRUCTURE OF HIV1 PROTEASE IN SITU PRODUCT COMPLEX  |   ANTI-PARALLEL BETA SHEET, HYDROLASE 
2z54:A    (LYS45) to    (GLY94)  THE INFLUENCE OF I47A MUTATION ON REDUCED SUSCEPTIBILITY TO THE PROTEASE INHIBITOR LOPINAVIR  |   COMPLEX (ASPARTIC PROTEASE/INHIBITOR), ASPARTIC PROTEASE, RESISTANT STRAIN, HYDROLASE 
2z54:B    (LYS45) to    (GLY94)  THE INFLUENCE OF I47A MUTATION ON REDUCED SUSCEPTIBILITY TO THE PROTEASE INHIBITOR LOPINAVIR  |   COMPLEX (ASPARTIC PROTEASE/INHIBITOR), ASPARTIC PROTEASE, RESISTANT STRAIN, HYDROLASE 
1lzq:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF THE COMPLEX OF MUTANT HIV-1 PROTEASE (A71V, V82T, I84V) WITH AN ETHYLENAMINE PEPTIDOMIMETIC INHIBITOR BOC-PHE- PSI[CH2CH2NH]-PHE-GLU-PHE-NH2  |   HIV, PEPTIDOMIMETIC, ETHYLENAMINE ISOSTERE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3ka2:A   (PRO148) to   (GLY198)  CRYSTAL STRUCTURE OF CHEMICALLY SYNTHESIZED 203 AMINO ACID 'COVALENT DIMER' [L-ALA;GLY51']HIV-1 PROTEASE MOLECULE COMPLEXED WITH MVT-101 REDUCED ISOSTERE INHIBITOR AT 1.4 A RESOLUTION  |   BETA-BARREL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3kfs:B    (GLY52) to    (GLY94)  HIV PROTEASE (PR) DIMER WITH INHIBITOR TL-3 BOUND AND FRAGMENT 2F4 IN THE OUTSIDE/TOP OF FLAP  |   HIV-1, PROTEASE, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1mer:A    (LYS45) to    (GLY94)  HIV-1 MUTANT (I84V) PROTEASE COMPLEXED WITH DMP450  |   HYDROLASE, ACID PROTEINASE, ASPARTYL PROTEASE 
3a2o:A    (ARG41) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH KNI-1689  |   HIV-1 PROTEASE, INHIBITOR, ASPARTYL PROTEASE, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3a2o:B   (GLY152) to   (GLY194)  CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH KNI-1689  |   HIV-1 PROTEASE, INHIBITOR, ASPARTYL PROTEASE, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
1ytg:B    (LYS45) to    (GLY94)  SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT  |   AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE, RNA- DIRECTED DNA POLYMERASE, HYDROLASE-PEPTIDE COMPLEX 
5e5j:A    (GLY52) to    (GLY94)  JOINT X-RAY/NEUTRON STRUCTURE OF HIV-1 PROTEASE TRIPLE MUTANT (V32I, I47V,V82I) WITH DARUNAVIR AT PH 6.0  |   PROTEASE HIV-1 DRUG RESISTANT MUTANT INHIBITOR COMPLEX, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
5e5j:B    (LYS45) to    (GLY94)  JOINT X-RAY/NEUTRON STRUCTURE OF HIV-1 PROTEASE TRIPLE MUTANT (V32I, I47V,V82I) WITH DARUNAVIR AT PH 6.0  |   PROTEASE HIV-1 DRUG RESISTANT MUTANT INHIBITOR COMPLEX, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
5e5k:A    (GLY52) to    (GLY94)  JOINT X-RAY/NEUTRON STRUCTURE OF HIV-1 PROTEASE TRIPLE MUTANT (V32I, I47V,V82I) WITH DARUNAVIR AT PH 4.3  |   PROTEASE DRUG RESISTANT MUTANT INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5e5k:B    (GLY52) to    (GLY94)  JOINT X-RAY/NEUTRON STRUCTURE OF HIV-1 PROTEASE TRIPLE MUTANT (V32I, I47V,V82I) WITH DARUNAVIR AT PH 4.3  |   PROTEASE DRUG RESISTANT MUTANT INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4qj2:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH WT P1-P6 SUBSTRATE  |   CO-EVOLUTION, PROTEASE, HYDROLASE 
4qj2:C    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH WT P1-P6 SUBSTRATE  |   CO-EVOLUTION, PROTEASE, HYDROLASE 
4qj2:D    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH WT P1-P6 SUBSTRATE  |   CO-EVOLUTION, PROTEASE, HYDROLASE 
4qlh:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF DRUG RESISTANT V82S/V1082S HIV-1 PROTEASE  |   TETHERED HIV-1 PROTEASE DIMER, PEPTIDE BOND HYDROLYSIS, HYDROLASE 
4qlh:A  (LYS1045) to  (GLY1094)  CRYSTAL STRUCTURE OF DRUG RESISTANT V82S/V1082S HIV-1 PROTEASE  |   TETHERED HIV-1 PROTEASE DIMER, PEPTIDE BOND HYDROLYSIS, HYDROLASE 
3nyg:A    (LYS45) to    (GLY94)  X-RAY STRUCTURE OF ESTER CHEMICAL ANALOGUE [O-GLY51,O-GLY51']HIV-1 PROTEASE COMPLEXED WITH MVT-101 INHIBITOR  |   BETA-BARREL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4rvi:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH NON-PEPTIDIC INHIBITOR, GRL0519  |   HIV-1 PROTEASE-INHIBITOR COMPLEX, GRL0519, G52, PROTEASE INHIBITOR, NON-PEPTIDIC PROTEASE INHIBITOR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4rvi:B    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH NON-PEPTIDIC INHIBITOR, GRL0519  |   HIV-1 PROTEASE-INHIBITOR COMPLEX, GRL0519, G52, PROTEASE INHIBITOR, NON-PEPTIDIC PROTEASE INHIBITOR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4rvi:C    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH NON-PEPTIDIC INHIBITOR, GRL0519  |   HIV-1 PROTEASE-INHIBITOR COMPLEX, GRL0519, G52, PROTEASE INHIBITOR, NON-PEPTIDIC PROTEASE INHIBITOR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4rvi:D    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH NON-PEPTIDIC INHIBITOR, GRL0519  |   HIV-1 PROTEASE-INHIBITOR COMPLEX, GRL0519, G52, PROTEASE INHIBITOR, NON-PEPTIDIC PROTEASE INHIBITOR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4rvj:B    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH AMPRENAVIR  |   HIV-1 PROTEASE-INHIBITOR COMPLEX, AMPRENAVIR, NON-PEPTIDIC PROTEASE INHIBITOR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4rvj:D    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH AMPRENAVIR  |   HIV-1 PROTEASE-INHIBITOR COMPLEX, AMPRENAVIR, NON-PEPTIDIC PROTEASE INHIBITOR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4cp7:A    (LYS45) to    (GLY94)  MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL  |   HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, ENZYME 
3d1y:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV-1 MUTANT I54V AND INHIBITOR SAQUINA  |   DRUG RESISTANCE, HIV-1, I54V, FLAP MUTANT, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4cpq:A    (LYS45) to    (GLY94)  MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL  |   HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN 
3o9c:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD20  |   HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3dck:A    (PRO44) to    (GLY94)  X-RAY STRUCTURE OF D25N CHEMICAL ANALOGUE OF HIV-1 PROTEASE COMPLEXED WITH KETOMETHYLENE ISOSTERE INHIBITOR  |   HIV-1 PROTEASE, HOMODIMER, BETA-TURNS, BETA-STRAND, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3ogq:B    (GLY52) to   (ASN111)  CRYSTAL STRUCTURE OF 6S-98S FIV PROTEASE WITH LOPINAVIR BOUND  |   ASPARTYL PROTEASE, HIV-LIKE FIV CHIMERA, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3ok9:B   (LYS145) to   (GLY194)  CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE WITH NEW OXATRICYCLIC DESIGNED INHIBITOR GRL-0519A  |   ASPARTIC ACID PROTEASE, HIV-1 PROTEASE INHIBITOR GRL-0519A, OXATRICYCLIC LIGANDS, MULTIDRUG-RESISTANT HIV STRAINS, WILD-TYPE HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3oxc:A    (LYS45) to    (GLY94)  WILD TYPE HIV-1 PROTEASE WITH ANTIVIRAL DRUG SAQUINAVIR  |   ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, SAQUINAVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4e43:A    (LYS45) to    (GLY94)  HIV PROTEASE (PR) DIMER WITH ACETATE IN EXO SITE AND PEPTIDE IN ACTIVE SITE  |   HIV-1 PROTEASE, EXO SITE, ASPARTYL PROTEASE, FRAGMENT SCREEN, HYDROLASE 
3pwm:A    (LYS45) to    (GLY94)  HIV-1 PROTEASE MUTANT L76V WITH DARUNAVIR  |   HIV-1, PROTEASE, MUTATION L76V, DARUNAVIR, HYDROLASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX 
4ejl:B    (LYS45) to    (GLY94)  APO HIV PROTEASE (PR) DIMER IN CLOSED FORM WITH FRAGMENT 1F1-N IN THE OUTSIDE/TOP OF FLAP  |   APO PROTEASE, ALLOSTERY, FRAGMENT BINDING, HYDROLASE 
4ep3:A   (GLY152) to   (GLY194)  CRYSTAL STRUCTURE OF INACTIVE SINGLE CHAIN WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH THE SUBSTRATE CA-P2  |   HIV-1 PROTEASE, SPECIFICITY DESIGN, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE SUBSTRATE COMPLEX 
5ivq:A    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH METHYL N-[(1S)-1- BENZHYDRYL-2-(3-MORPHOLIN-4-IUM-2-YLPROPYLAMINO)-2-OXO- ETHYL]CARBAMATE  |   HIV, PROTEASE, HYDROLASE-INHIBITOR COMPLEX 
3qaa:A    (LYS45) to    (GLY94)  HIV-1 WILD TYPE PROTEASE WITH A SUBSTITUTED BIS-TETRAHYDROFURAN INHIBITOR, GRL-044-10A  |   ASPARTIC ACID PROTEASE, HIV-1 PROTEASE INHIBITOR GRL-044-10A, SUBSTITUTED BIS-TETRAHYDROFURAN INHIBITOR, WILD-TYPE HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4f73:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF ACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE N TERMINAL PRODUCT OF CA-P2 CLEAVAGE SITE  |   HIV-1 PROTEASE, SUBSTRATE COMPLEX, AIDS, PRODUCT COMPLEX, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE PRODUCT COMPLEX 
4f73:B    (LYS45) to    (GLY94)  CRYSTAL STRUCTURE OF ACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE N TERMINAL PRODUCT OF CA-P2 CLEAVAGE SITE  |   HIV-1 PROTEASE, SUBSTRATE COMPLEX, AIDS, PRODUCT COMPLEX, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE PRODUCT COMPLEX 
5kao:A    (GLY52) to    (GLY94)  CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL- 10413  |   GRL-10413, HIV-1 PROTEASE, PROTEASE-INHIBITOR, DARUNAVIR, 2- CHLOROANISOLE, NONPEPTIDIC, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5kao:B    (GLY40) to    (GLY94)  CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL- 10413  |   GRL-10413, HIV-1 PROTEASE, PROTEASE-INHIBITOR, DARUNAVIR, 2- CHLOROANISOLE, NONPEPTIDIC, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
5kqz:A    (LYS45) to    (GLY94)  PROTEASE E35D-CAP2  |   HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX