12ca:A   (ALA115) to   (LEU212)  ALTERING THE MOUTH OF A HYDROPHOBIC POCKET. STRUCTURE AND KINETICS OF HUMAN CARBONIC ANHYDRASE II MUTANTS AT RESIDUE VAL-121  |   LYASE(OXO-ACID) 
3rld:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE Y7I MUTANT OF HUMAN CARBONIC ANHYDRASE II  |   ZINC METALLOENZYME, HISTIDINE LIGANDS, Y7I MUTATION, LYASE 
1a42:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH BRINZOLAMIDE  |   LYASE, ZINC, INHIBITOR 
2aw1:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE INHIBITORS: VALDECOXIB BINDS TO A DIFFERENT ACTIVE SITE REGION OF THE HUMAN ISOFORM II AS COMPARED TO THE STRUCTURALLY RELATED CYCLOOXYGENASE II "SELECTIVE" INHIBITOR CELECOXIB  |   CARBONIC ANHYDRASE, PROTEIN-INHIBITOR COMPLEX, LYASE 
3efi:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE ACTIVATORS: KINETIC AND X-RAY CRYSTALLOGRAPHIC STUDY FOR THE INTERACTION OF D- AND L- TRYPTOPHAN WITH THE MAMMALIAN ISOFORMS I-XIV  |   CARBONIC ANHYDRASE, ACTIVATORS, CRYSTAL STRUCTURE, AMINOACIDS, OXO-ACID, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL-BINDING, POLYMORPHISM, ZINC 
2ax2:A   (ALA115) to   (LEU212)  PRODUCTION AND X-RAY CRYSTALLOGRAPHIC ANALYSIS OF FULLY DEUTERATED HUMAN CARBONIC ANHYDRASE II  |   PERDEURATED HUMAN CARBONIC ANHYDRASE II PROTON TRANSFER, LYASE 
4wl4:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH THE 6-HYDROXY-CHROMENE-2-THIONE INHIBITOR  |   LYASE 
1am6:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II INHIBITOR: ACETOHYDROXAMATE  |   HYDROLASE, CO2 HYDRATION 
3ryj:B   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE COMPLEXED WITH 4-SULFAMOYL-N-(2,2,2- TRIFLUOROETHYL)BENZAMIDE  |   ALPHA BETA, LYASE 
3ryv:B   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE COMPLEXED WITH N-ETHYL-4-SULFAMOYLBENZAMIDE  |   ALPHA BETA, LYASE 
3ryx:B   (ALA115) to   (LEU212)  FLUOROALKYL AND ALKYL CHAINS HAVE SIMILAR HYDROPHOBICITIES IN BINDING TO THE HYDROPHOBIC WALL OF CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
3ryz:A   (ALA115) to   (LEU212)  FLUOROALKYL AND ALKYL CHAINS HAVE SIMILAR HYDROPHOBICITIES IN BINDING TO THE HYDROPHOBIC WALL OF CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
3rz0:B   (ALA115) to   (LEU212)  FLUOROALKYL AND ALKYL CHAINS HAVE SIMILAR HYDROPHOBICITIES IN BINDING TO THE HYDROPHOBIC WALL OF CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
3rz1:B   (ALA115) to   (LEU212)  FLUOROALKYL AND ALKYL CHAINS HAVE SIMILAR HYDROPHOBICITIES IN BINDING TO THE HYDROPHOBIC WALL OF CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
3rz5:A   (ALA115) to   (LEU212)  FLUOROALKYL AND ALKYL CHAINS HAVE SIMILAR HYDROPHOBICITIES IN BINDING TO THE HYDROPHOBIC WALL OF CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
3rz7:A   (ALA115) to   (LEU212)  FLUOROALKYL AND ALKYL CHAINS HAVE SIMILAR HYDROPHOBICITIES IN BINDING TO THE HYDROPHOBIC WALL OF CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
3rz8:A   (ALA115) to   (LEU212)  FLUOROALKYL AND ALKYL CHAINS HAVE SIMILAR HYDROPHOBICITIES IN BINDING TO THE HYDROPHOBIC WALL OF CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
2osf:A   (ALA115) to   (LEU211)  INHIBITION OF CARBONIC ANHYDRASE II BY THIOXOLONE: A MECHANISTIC AND STRUCTURAL STUDY  |   CARBONIC ANHYDRASE II, THIOXOLONE, THERAPEUTIC CA INHIBITORS, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL-BINDING, POLYMORPHISM, ZINC 
2osm:A   (ALA115) to   (LEU211)  INHIBITION OF CARBONIC ANHYDRASE II BY THIOXOLONE: A MECHANISTIC AND STRUCTURAL STUDY  |   HUMAN CARBONIC ANHYDRASE II, 2-HYDROXYTHIOPHENOL, LYASE 
4wr7:A   (SER115) to   (CYS212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME I WITH 2,3,5,6- TETRAFLUORO-4-(PROPYLTHIO)BENZENESULFONAMIDE.  |   DRUG DESIGN, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, LYASE 
4wr7:B   (SER115) to   (CYS212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME I WITH 2,3,5,6- TETRAFLUORO-4-(PROPYLTHIO)BENZENESULFONAMIDE.  |   DRUG DESIGN, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, LYASE 
4wup:A   (SER115) to   (CYS212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME I WITH 4-[(2- HYDROXYETHYL)THIO]BENZENESULFONAMIDE  |   DRUG DESIGN, LYASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4wup:B   (SER115) to   (CYS212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME I WITH 4-[(2- HYDROXYETHYL)THIO]BENZENESULFONAMIDE  |   DRUG DESIGN, LYASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4wuq:A   (SER115) to   (CYS212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME I WITH 2,3,5,6- TETRAFLUORO-4-PIPERIDIN-1-YLBENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, LYASE 
4wuq:B   (SER115) to   (CYS212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME I WITH 2,3,5,6- TETRAFLUORO-4-PIPERIDIN-1-YLBENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, LYASE 
4hba:A   (ALA115) to   (LEU212)  STRUCTURAL AND CATALYTIC CHARACTERIZATION OF A THERMAL AND ACID STABLE VARIANT OF HUMAN CARBONIC ANHYDRASE II CONTAINING AN ENGINEERED DISULFIDE BOND  |   HUMAN CARBONIC ANHYDRASE II, THERMAL STABILITY, LYASE 
4ww6:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 2,3,5,6- TETRAFLUORO-4-(PROPYLTHIO)BENZENESULFONAMIDE  |   DRUG DESIGN, LYASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4hew:A   (ALA115) to   (LEU212)  ACTIVITY ENHANCERS OF H64A VARIANT OF HUMAN CARBONIC ANHYDRASE II POSSESS MULTIPLE BINDING SITES WITHIN AND AROUND THE ENZYME STRUCTURE  |   HYDRATION/DEHYDRATION, HIS64ALA, LYASE 
4hey:A   (ALA115) to   (LEU212)  ACTIVITY ENHANCERS OF H64A VARIANT OF HUMAN CARBONIC ANHYDRASE II POSSESS MULTIPLE BINDING SITES WITHIN AND AROUND THE ENZYME STRUCTURE  |   HYDRATION/DEHYDRATION, HIS64ALA, LYASE 
4hez:A   (ALA115) to   (LEU212)  ACTIVITY ENHANCERS OF H64A VARIANT OF HUMAN CARBONIC ANHYDRASE II POSSESS MULTIPLE BINDING SITES WITHIN AND AROUND THE ENZYME STRUCTURE  |   HYDRATION/DEHYDRATION, HIS64ALA, LYASE 
4hf3:A   (ALA115) to   (LEU212)  ACTIVITY ENHANCERS OF H64A VARIANT OF HUMAN CARBONIC ANHYDRASE II POSSESS MULTIPLE BINDING SITES WITHIN AND AROUND THE ENZYME STRUCTURE  |   HYDRATION/DEHYDRATION, HIS64ALA, LYASE 
1bcd:A   (ALA115) to   (LEU212)  X-RAY CRYSTALLOGRAPHIC STRUCTURE OF A COMPLEX BETWEEN HUMAN CARBONIC ANHYDRASE II AND A NEW TOPICAL INHIBITOR, TRIFLUOROMETHANE SULPHONAMIDE  |   LYASE(OXO-ACID) 
1bn1:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II INHIBITOR  |   CO2 HYDRATION, ZINC ENZYME, LYASE 
1bn3:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II INHIBITOR  |   CO2 HYDRATION, ZINC ENZYME, LYASE 
1bn4:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II INHIBITOR  |   CO2 HYDRATION, ZINC ENZYME, LYASE 
1bnm:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II INHIBITOR  |   CO2 HYDRATION, ZINC ENZYME, LYASE 
1bnn:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II INHIBITOR  |   CO2 HYDRATION, ZINC ENZYME, LYASE 
1bnq:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II INHIBITOR  |   CO2 HYDRATION, ZINC ENZYME, LYASE 
1bnt:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II INHIBITOR  |   CO2 HYDRATION, ZINC ENZYME, LYASE 
1bnu:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II INHIBITOR  |   CO2 HYDRATION, ZINC ENZYME, LYASE 
1bnv:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II INHIBITOR  |   CO2 HYDRATION, ZINC ENZYME, LYASE 
1bnw:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II INHIBITOR  |   CO2 HYDRATION, ZINC ENZYME, LYASE 
3s72:B   (ALA115) to   (LEU212)  THE ORIGIN OF THE HYDROPHOBIC EFFECT IN THE MOLECULAR RECOGNITION OF ARYLSULFONAMIDES BY CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
3s73:B   (ALA115) to   (LEU212)  THE ORIGIN OF THE HYDROPHOBIC EFFECT IN THE MOLECULAR RECOGNITION OF ARYLSULFONAMIDES BY CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
3s74:B   (ALA115) to   (LEU212)  THE ORIGIN OF THE HYDROPHOBIC EFFECT IN THE MOLECULAR RECOGNITION OF ARYLSULFONAMIDES BY CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
3s75:B   (ALA115) to   (LEU212)  THE ORIGIN OF THE HYDROPHOBIC EFFECT IN THE MOLECULAR RECOGNITION OF ARYLSULFONAMIDES BY CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
3s76:A   (ALA115) to   (LEU212)  THE ORIGIN OF THE HYDROPHOBIC EFFECT IN THE MOLECULAR RECOGNITION OF ARYLSULFONAMIDES BY CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
3s78:B   (ALA115) to   (LEU212)  THE ORIGIN OF THE HYDROPHOBIC EFFECT IN THE MOLECULAR RECOGNITION OF ARYLSULFONAMIDES BY CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
3s8x:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-{[(4- METHYL-6-OXO-1,6-DIHYDRO-2-PYRIMIDINYL) SULFANYL]ACETYL}BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, SULFONAMIDE, METAL-BINDING, LYASE- LYASE INHIBITOR COMPLEX 
3s97:A   (PRO150) to   (PHE249)  PTPRZ CNTN1 COMPLEX  |   CARBONIC ANHDYRASE LIKE IMMUNOGLOBULIN, CELL ADHESION COMPLEX, CELL ADHESION 
3s97:B   (PRO150) to   (PHE249)  PTPRZ CNTN1 COMPLEX  |   CARBONIC ANHDYRASE LIKE IMMUNOGLOBULIN, CELL ADHESION COMPLEX, CELL ADHESION 
1bv3:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH UREA  |   CARBONATE HYDRO-LYASE 
3s9t:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 2- CHLORO-5-{[(4,6-DIMETHYL-2-PYRIMIDINYL) SULFANYL]ACETYL}BENZENESULFONAMIDE  |   DRUG DESIGN, SULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3sap:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-{[(5- BUTYL-2-PYRIMIDINYL)SULFANYL]ACETYL}BENZENESULFONAMIDE  |   DRUG DESIGN, SULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4ht0:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH THE INHIBITOR.  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, CARBON-OXYGEN LYASE ACTIVITY 
3sbh:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-{[(4, 6-DIMETHYL-2-PYRIMIDINYL)SULFANYL]ACETYL}BENZENESULFONAMIDE  |   DRUG DESIGN, SULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3sbi:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-[(2- PYRIMIDINYLSULFANYL)ACETYL]BENZENESULFONAMIDE  |   DRUG DESIGN, SULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4hu1:B   (ALA117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH THE INHIBITOR.  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE,METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, CARBONATE DEHYDRATASE ACTIVITY, CARBON-OXYGEN LYASE ACTIVITY 
4hu1:A   (ALA117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH THE INHIBITOR.  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE,METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, CARBONATE DEHYDRATASE ACTIVITY, CARBON-OXYGEN LYASE ACTIVITY 
3fe4:A   (VAL134) to   (LEU233)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE VI  |   CARBONIC ANHYDRASE, SECRETION, METAL BINDING, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, GLYCOPROTEIN, LYASE, METAL- BINDING, SECRETED 
4xe1:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 6-SULFAMOYL-SACCHARIN  |   CYTOPLASM, LYASE, INHIBITOR 
2pou:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 4,5-DICHLORO-BENZENE-1,3-DISULFONAMIDE  |   CARBONIC ANHYDRASE II, PROTEIN-INHIBITOR COMPLEXES, LYASE 
2pov:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 4-AMINO-6-CHLORO-BENZENE-1,3-DISULFONAMIDE  |   CARBONIC ANHYDRASE II, PROTEIN-INHIBITOR COMPLEXES, LYASE 
2pow:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 4-AMINO-6-TRIFLUOROMETHYL-BENZENE-1,3- DISULFONAMIDE  |   CARBONIC ANHYDRASE II, PROTEIN-INHIBITOR COMPLEXES, LYASE 
1cah:A   (ALA115) to   (LEU212)  STRUCTURE OF COBALT CARBONIC ANHYDRASE COMPLEXED WITH BICARBONATE  |   LYASE(OXO-ACID) 
1cai:A   (ALA115) to   (LEU212)  STRUCTURAL ANALYSIS OF THE ZINC HYDROXIDE-THR 199-GLU 106 HYDROGEN BONDING NETWORK IN HUMAN CARBONIC ANHYDRASE II  |   LYASE(OXO-ACID) 
1cak:A   (ALA115) to   (LEU212)  STRUCTURAL ANALYSIS OF THE ZINC HYDROXIDE-THR 199-GLU 106 HYDROGEN BONDING NETWORK IN HUMAN CARBONIC ANHYDRASE II  |   LYASE(OXO-ACID) 
1cam:A   (ALA115) to   (LEU212)  STRUCTURAL ANALYSIS OF THE ZINC HYDROXIDE-THR 199-GLU 106 HYDROGEN BONDING NETWORK IN HUMAN CARBONIC ANHYDRASE II  |   LYASE(OXO-ACID) 
1cao:A   (ALA115) to   (LEU212)  CRYSTALLOGRAPHIC STUDIES OF THE BINDING OF PROTONATED AND UNPROTONATED INHIBITORS TO CARBONIC ANHYDRASE USING HYDROGEN SULPHIDE AND NITRATE ANIONS  |   LYASE(OXO-ACID) 
1cct:A   (ALA115) to   (LEU212)  STRUCTURE-ASSISTED REDESIGN OF A PROTEIN-ZINC BINDING SITE WITH FEMTOMOLAR AFFINITY  |   LYASE (OXO-ACID) 
1okl:A   (ALA115) to   (LEU211)  CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKL INHIBITOR 5- DIMETHYLAMINO-NAPHTHALENE-1-SULFONAMIDE  |   LYASE (OXO-ACID), INHIBITOR 
1okm:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKM INHIBITOR 4- SULFONAMIDE-[1-(4-AMINOBUTANE)]BENZAMIDE  |   LYASE (OXO-ACID), INHIBITOR 
1cil:A   (ALA115) to   (LEU212)  THE POSITIONS OF HIS-64 AND A BOUND WATER IN HUMAN CARBONIC ANHYDRASE II UPON BINDING THREE STRUCTURALLY RELATED INHIBITORS  |   LYASE(OXO-ACID) 
1cim:A   (ALA115) to   (LEU212)  THE POSITIONS OF HIS-64 AND A BOUND WATER IN HUMAN CARBONIC ANHYDRASE II UPON BINDING THREE STRUCTURALLY RELATED INHIBITORS  |   LYASE(OXO-ACID) 
1cin:A   (ALA115) to   (LEU212)  THE POSITIONS OF HIS-64 AND A BOUND WATER IN HUMAN CARBONIC ANHYDRASE II UPON BINDING THREE STRUCTURALLY RELATED INHIBITORS  |   LYASE(OXO-ACID) 
1oq5:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH NANOMOLAR INHIBITOR  |   10-STRANDED, TWISTED BETA-SHEET, METAL BINDING PROTEIN 
1cnc:A   (ALA115) to   (LEU212)  COMPENSATORY PLASTIC EFFECTS IN THE REDESIGN OF PROTEIN- ZINC BINDING SITES  |   LYASE(OXO-ACID) 
1cng:A   (ALA115) to   (LEU212)  X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE  |   LYASE (OXO-ACID) 
1cnh:A   (ALA115) to   (LEU212)  X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE  |   LYASE (OXO-ACID) 
1cni:A   (ALA115) to   (LEU212)  X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE  |   LYASE (OXO-ACID) 
1cnj:A   (ALA115) to   (LEU212)  X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE  |   LYASE (OXO-ACID) 
1cnk:A   (ALA115) to   (LEU212)  X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE  |   LYASE (OXO-ACID) 
1cnw:A   (ALA115) to   (LEU212)  SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS  |   LYASE (OXO-ACID) 
1cny:A   (ALA115) to   (LEU212)  SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS  |   LYASE (OXO-ACID) 
2q1b:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH SACCHARIN  |   10-STRANDED, TWISTED BETA-SHEET, LYASE 
2q1q:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE INHIBITORS. INTERACTION OF THE ANTIEPILEPTIC DRUG SULTHIAME WITH TWELVE MAMMALIAN ISOFORMS: KINETIC AND X-RAY CRYSTALLOGRAPHIC STUDIES  |   ANTIEPILEPTIC, CARBONIC ANHYDRASE, INHIBITORS, CRYSTAL STRUCTURE, LYASE 
1cra:A   (ALA115) to   (LEU212)  THE COMPLEX BETWEEN HUMAN CARBONIC ANHYDRASE II AND THE AROMATIC INHIBITOR 1,2,4-TRIAZOLE  |   LYASE(OXO-ACID) 
1crm:A   (SER115) to   (CYS212)  STRUCTURE AND FUNCTION OF CARBONIC ANHYDRASES  |   LYASE (OXO-ACID) 
4idr:X   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II PROTON TRANSFER DOUBLE MUTANT  |   GOLOBULAR PROTEIN, LYASE 
1cvb:A   (ALA115) to   (LEU212)  STRUCTURAL AND FUNCTIONAL IMPORTANCE OF A CONSERVED HYDROGEN BOND NETWORK IN HUMAN CARBONIC ANHYDRASE II  |   LYASE(OXO-ACID) 
1cvd:A   (ALA115) to   (LEU212)  STRUCTURAL CONSEQUENCES OF REDESIGNING A PROTEIN-ZINC BINDING SITE  |   LYASE(OXO-ACID) 
1cve:A   (ALA115) to   (LEU212)  STRUCTURAL CONSEQUENCES OF REDESIGNING A PROTEIN-ZINC BINDING SITE  |   LYASE(OXO-ACID) 
1cvf:A   (ALA115) to   (LEU212)  STRUCTURAL CONSEQUENCES OF REDESIGNING A PROTEIN-ZINC BINDING SITE  |   LYASE(OXO-ACID) 
1cvh:A   (ALA115) to   (LEU212)  STRUCTURAL CONSEQUENCES OF REDESIGNING A PROTEIN-ZINC BINDING SITE  |   HYDRO-LYASE 
2cbd:A   (ALA115) to   (LEU212)  STRUCTURE OF NATIVE AND APO CARBONIC ANHYDRASE II AND SOME OF ITS ANION-LIGAND COMPLEXES  |   LYASE(OXO-ACID) 
2cba:A   (ALA115) to   (LEU212)  STRUCTURE OF NATIVE AND APO CARBONIC ANHYDRASE II AND SOME OF ITS ANION-LIGAND COMPLEXES  |   LYASE(OXO-ACID) 
2cbb:A   (ALA115) to   (LEU212)  STRUCTURE OF NATIVE AND APO CARBONIC ANHYDRASE II AND SOME OF ITS ANION-LIGAND COMPLEXES  |   LYASE(OXO-ACID) 
2cbc:A   (ALA115) to   (LEU212)  STRUCTURE OF NATIVE AND APO CARBONIC ANHYDRASE II AND SOME OF ITS ANION-LIGAND COMPLEXES  |   LYASE(OXO-ACID) 
2cbe:A   (ALA115) to   (LEU212)  STRUCTURE OF NATIVE AND APO CARBONIC ANHYDRASE II AND SOME OF ITS ANION-LIGAND COMPLEXES  |   LYASE(OXO-ACID) 
1dca:A   (ALA115) to   (LEU212)  STRUCTURE OF AN ENGINEERED METAL BINDING SITE IN HUMAN CARBONIC ANHYDRASE II REVEALS THE ARCHITECTURE OF A REGULATORY CYSTEINE SWITCH  |   LYASE(OXO-ACID) 
1dcb:A   (ALA115) to   (LEU212)  STRUCTURE OF AN ENGINEERED METAL BINDING SITE IN HUMAN CARBONIC ANHYDRASE II REVEALS THE ARCHITECTURE OF A REGULATORY CYSTEINE SWITCH  |   LYASE(OXO-ACID) 
1dmx:A   (PRO115) to   (GLN212)  MURINE MITOCHONDRIAL CARBONIC ANYHDRASE V AT 2.45 ANGSTROMS RESOLUTION  |   PROTON TRANSFER, LYASE (OXO-ACID) 
1dmx:B   (PRO115) to   (GLN212)  MURINE MITOCHONDRIAL CARBONIC ANYHDRASE V AT 2.45 ANGSTROMS RESOLUTION  |   PROTON TRANSFER, LYASE (OXO-ACID) 
1dmy:A   (PRO115) to   (GLN212)  COMPLEX BETWEEN MURINE MITOCHONDRIAL CARBONIC ANYHDRASE V AND THE TRANSITION STATE ANALOGUE ACETAZOLAMIDE  |   PROTON TRANSFER, LYASE (OXO-ACID) 
1dmy:B   (PRO115) to   (GLN212)  COMPLEX BETWEEN MURINE MITOCHONDRIAL CARBONIC ANYHDRASE V AND THE TRANSITION STATE ANALOGUE ACETAZOLAMIDE  |   PROTON TRANSFER, LYASE (OXO-ACID) 
2qo8:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE COMPLEX OF HCAII WITH AN INDANE-SULFONAMIDE INHIBITOR  |   CARBONIC ANHYDRASE II, LYASE 
2qoa:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE COMPLEX OF HCAII WITH AN INDANE-SULFONAMIDE INHIBITOR  |   CARBONIC ANHYDRASE II, LYASE 
2qp6:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF THE COMPLEX OF HCAII WITH A BIOREDUCTIVE ANTITUMOR DERIVATIVE  |   CARBONIC ANHYDRASE II, LYASE 
4ito:A   (ALA115) to   (LEU212)  HUMAN CA II INHIBITION BY NOVEL SULFONAMIDE  |   ALPHA BETA FOLD, REVERSIBLE HYDRATION OF CARBON DIOXIDE TO BICARBONATE AND PROTON, LYASE-LYASE INHIBITOR COMPLEX 
4itp:A   (ALA115) to   (LEU212)  STRUCTURE OF HUMAN CARBONIC ANHYDRASE II BOUND TO A BENZENE SULFONAMIDE  |   ALPHA BETA FOLD, REVERSIBLE HYDRATION OF CARBON DIOXIDE TO BICARBONATE AND PROTON, LYASE-LYASE INHIBITOR COMPLEX 
3t5u:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH N-HYDROXY BENZENESULFONAMIDE  |   PROTEIN-INHIBITOR COMPLEX, LYASE-LYASE INHIBITOR COMPLEX 
3t5z:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH N-METHOXY-BENZENESULFONAMIDE  |   PROTEIN-INHIBITOR COMPLEX, LYASE-LYASE INHIBITOR COMPLEX 
4iwz:A   (ALA115) to   (LEU212)  STRUCTURE OF HCAII IN COMPLEX WITH AN ACETAZOLAMIDE DERIVATIVE  |   ALPHA BETA FOLD, REVERSIBLE HYDRATION OF CARBON DI OXIDE TO BICARBONATE AND PROTON, LYASE-LYASE INHIBITOR COMPLEX 
3t82:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH ACETYLATED CARBOHYDRATE SULFAMATES  |   ALPHA CARBONIC ANHYDRASE, LYASE-LYASE INHIBITOR COMPLEX 
3t83:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH ACETYLATED CARBOHYDRATE SULFAMATES  |   ALPHA CARBONIC ANHYDRASE, LYASE-LYASE INHIBITOR COMPLEX 
3t85:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH ACETYLATED CARBOHYDRATE SULFAMATES  |   ALPHA CARBONIC ANHYDRASE, LYASE-LYASE INHIBITOR COMPLEX 
4y0j:A   (ALA115) to   (LEU212)  H/D EXCHANGED HUMAN CARBONIC ANHYDRASE II PH 6 ROOM TEMPERATURE NEUTRON CRYSTAL STRUCTURE.  |   NEUTRON, PROTON TRANSFER, H/D EXCHANGED, LYASE 
3tmj:A   (ALA115) to   (LEU212)  JOINT X-RAY/NEUTRON STRUCTURE OF HUMAN CARBONIC ANHYDRASE II AT PH 7.8  |   H/D EXCHANGED, JOINT NEUTRON/X-RAY REFINEMENT, LYASE 
3gz0:A   (ALA115) to   (LEU212)  APO-HUMAN CARBONIC ANHYDRASE II REVISITED: IMPLICATIONS OF THE LOSS OF A METAL IN PROTEIN STRUCTURE, STABILITY AND SOLVENT NETWORK  |   APO, CARBONIC ANHYDRASE, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL-BINDING, POLYMORPHISM, ZINC 
1eou:A   (ALA115) to   (LEU211)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH AN ANTICONVULSANT SUGAR SULFAMATE  |   HYDROLASE, CO2 HYDRATION, PROTEIN-INHIBITOR COMPLEX, LYASE 
3tvn:X   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II PROTON TRANSFER MUTANT  |   GLOBULAR PROTEIN, LYASE 
3tvo:X   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II PROTON TRANSFER DOUBLE MUTANT  |   GLOBULAR PROTEIN, LYASE 
4ygn:A   (ALA115) to   (LEU212)  NAI--INTERACTIONS BETWEEN HOFMEISTER ANIONS AND THE BINDING POCKET OF A PROTEIN  |   LYASE, HOFMEISTER ANIONS, HCAII 
4ygj:A   (ALA115) to   (LEU212)  NABR--INTERACTIONS BETWEEN HOFMEISTER ANIONS AND THE BINDING POCKET OF A PROTEIN  |   LYASE, HOFMEISTER ANIONS, HCAII 
4ygk:A   (ALA115) to   (LEU212)  NASCN--INTERACTIONS BETWEEN HOFMEISTER ANIONS AND THE BINDING POCKET OF A PROTEIN  |   LYASE, HOFMEISTER ANIONS, HCAII 
4ygl:A   (ALA115) to   (LEU212)  NACLO4--INTERACTIONS BETWEEN HOFMEISTER ANIONS AND THE BINDING POCKET OF A PROTEIN  |   LYASE, HOFMEISTER ANIONS, HCAII 
4js6:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF INHIBITOR-FREE HCAII H94D  |   LYASE 
4jsa:A   (ALA115) to   (LEU212)  BENZENESULFONAMIDE COMPLEXED WITH HCAII H94D  |   LYASE-LYASE INHIBITOR COMPLEX 
1f2w:A   (ALA115) to   (LEU212)  THE MECHANISM OF CYANAMIDE HYDRATION CATALYZED BY CARBONIC ANHYDRASE II REVEALED BY CRYOGENIC X-RAY DIFFRACTION  |   PROTEIN-INHIBITOR COMPLEX, LYASE 
4jss:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II H94D BOUND TO A BIDENTATE INHIBITOR  |   LYASE-LYASE INHIBITOR COMPLEX 
4jsw:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II H94C  |   LYASE-LYASE INHIBITOR COMPLEX 
4jsz:A   (ALA115) to   (LEU212)  BENZENESULFONAMIDE BOUND TO HCAII H94C  |   LYASE-LYASE INHIBITOR COMPLEX 
3u3a:X   (ALA115) to   (LEU212)  STRUCTURE OF HUMAN CARBONIC ANHYDRASE II V143I  |   LYASE, ZINC METALLOENZYME, V143I, ESTERASE, SITE DIRECTED MUTAGENESIS, CO2 BINDING POCKET 
3u45:X   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II V143A  |   LYASE, ZINC METALLOENZYME, V143A, ESTERASE, SITE DIRECTED MUTAGENESIS, HYDROPHOBIC POCKET 
3u47:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II V143L  |   LYASE, ZINC METALLOENZYME, V143L, ESTERASE, SITE DIRECTED MUTAGENESIS 
2eu2:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH NOVEL INHIBITORS  |   CARBONIC ANHYDRASE II PROTON TRANSFER INHIBITOR, LYASE 
2eu3:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH NOVEL INHIBITORS  |   CARBONIC ANHYDRASE II PROTON TRANSFER INHIBITOR, LYASE 
3hkn:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH (2,3,4,6-TETRA-O-ACETYL- BETA-D-GALACTOPYRANOSYL) -(1-4)-1,2,3,6-TETRA-O-ACETYL-1-THIO-BETA-D- GLUCOPYRANOSYLSULFONAMIDE  |   CARBONIC ANHYDRASE DRUG DESIGN, DISEASE MUTATION, LYASE, METAL- BINDING 
3hkq:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 1-S-D- GALACTOPYRANOSYLSULFONAMIDE  |   CARBONIC ANHYDRASE DRUG DESIGN, DISEASE MUTATION, LYASE, METAL- BINDING 
3hkt:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH ALPHA-D- GLUCOPYRANOSYL-(1->4)-1-THIO-BETA-D- GLUCOPYRANOSYLSULFONAMIDE  |   CARBONIC ANHYDRASE DRUG DESIGN, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL-BINDING, POLYMORPHISM, ZINC 
3hku:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH TOPIRAMATE  |   CARBONIC ANHYDRASE DRUG DESIGN, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL-BINDING, POLYMORPHISM, ZINC 
1ray:A   (ALA115) to   (LEU212)  THE STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BROMIDE AND AZIDE  |   LYASE(OXO-ACID) 
1raz:A   (ALA115) to   (LEU212)  THE STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BROMIDE AND AZIDE  |   LYASE(OXO-ACID) 
3hlj:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 3- METHYLTHIOBENZIMIDAZO[1,2-C][1,2,3]THIADIAZOL-7-SULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, SULFONAMIDE, THIADIAZOLE, LYASE, DISEASE MUTATION, METAL-BINDING 
2ez7:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE ACTIVATORS. ACTIVATION OF ISOZYMES I, II, IV, VA, VII AND XIV WITH L- AND D-HISTIDINE AND CRYSTALLOGRAPHIC ANALYSIS OF THEIR ADDUCTS WITH ISOFORM II: ENGINEERING PROTON TRANSFER PROCESSES WITHIN THE ACTIVE SITE OF AN ENZYME  |   CARBONIC ANHYDRASE II, ACTIVATORS, LYASE 
1fql:A   (ALA115) to   (LEU212)  X-RAY CRYSTAL STRUCTURE OF ZINC-BOUND F95M/W97V CARBONIC ANHYDRASE (CAII) VARIANT  |   CARBONIC ANHYDRASE, METAL BINDING, METAL SPECIFICITY, LYASE 
1fqm:A   (ALA115) to   (LEU212)  X-RAY CRYSTAL STRUCTURE OF ZINC-BOUND F93I/F95M/W97V CARBONIC ANHYDRASE (CAII) VARIANT  |   CARBONIC ANHYDRASE, METAL BINDING, METAL SPECIFICITY, LYASE 
1fqr:A   (ALA115) to   (LEU212)  X-RAY CRYSTAL STRUCTURE OF COBALT-BOUND F93I/F95M/W97V CARBONIC ANHYDRASE (CAII) VARIANT  |   CARBONIC ANHYDRASE, METAL BINDING, METAL SPECIFICITY, COBALT, LYASE 
1fr4:A   (ALA115) to   (LEU212)  X-RAY CRYSTAL STRUCTURE OF COPPER-BOUND F93I/F95M/W97V CARBONIC ANHYDRASE (CAII) VARIANT  |   CARBONIC ANHYDRASE, METAL BINDING, METAL SPECIFICITY, COPPER, LYASE 
2f14:A   (ALA115) to   (LEU212)  TNE CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A FLUORESCENT INHIBITOR  |   CARBONIC ANHYDRASE II, LYASE 
1fsr:A   (ALA115) to   (LEU212)  X-RAY CRYSTAL STRUCTURE OF COPPER-BOUND F93S/F95L/W97M CARBONIC ANHYDRASE (CAII) VARIANT  |   CARBONIC ANHYDRASE, METAL BINDING, METAL SPECIFICITY, COPPER, LYASE 
1fsr:B   (ALA115) to   (LEU212)  X-RAY CRYSTAL STRUCTURE OF COPPER-BOUND F93S/F95L/W97M CARBONIC ANHYDRASE (CAII) VARIANT  |   CARBONIC ANHYDRASE, METAL BINDING, METAL SPECIFICITY, COPPER, LYASE 
4yvy:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH HYDROXYLAMINE-O-SULFONAMIDE, A MOLECULE INCORPORATING TWO ZINC- BINDING GROUPS.  |   PROTEIN-INHIBITOR COMPLEX, LYASE 
4yx4:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH AN INHIBITOR WITH A BENZENESULFONAMIDE GROUP (1).  |   PROTEIN-LIGAND-COMPLEX, LYASE 
4yxo:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH AN INHIBITOR WITH A BENZENESULFONAMIDE GROUP (3).  |   LYASE 
4kap:A   (ALA115) to   (LEU212)  THE BINDING OF BENZOARYLSULFONAMIDE LIGANDS TO HUMAN CARBONIC ANHYDRASE IS INSENSITIVE TO FORMAL FLUORINATION OF THE LIGAND  |   ALPHA BETA, LYASE 
4yxi:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH AN INHIBITOR WITH A BENZENESULFONAMIDE GROUP (2).  |   PROTEIN-INHIBITOR COMPLEX, LYASE 
4yxu:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH AN INHIBITOR WITH A BENZENESULFONAMIDE GROUP (4).  |   LYASE 
4yyt:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH AN INHIBITOR WITH A BENZENESULFONAMIDE GROUP (5).  |   LYASE 
1g0e:A   (ALA115) to   (LEU212)  SITE-SPECIFIC MUTANT (HIS64 REPLACED WITH ALA) OF HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH 4-METHYLIMIDAZOLE  |   TWISTED BETA SHEET, CHEMICAL RESCUE, 4-METHYLIMIDAZOLE, ZINC METALLOENZYME,PROTEIN LIGAND COMPLEX, LYASE 
1g0f:A   (ALA115) to   (LEU212)  SITE-SPECIFIC MUTANT (HIS64 REPLACED WITH ALA) OF HUMAN CARBONIC ANHYDRASE II  |   TWISTED BETA SHEET, ZINC METALLOENZYME, LYASE 
4z1e:A   (ALA115) to   (LEU211)  CARBONIC ANHYDRASE INHIBITORS: DESIGN AND SYNTHESIS OF NEW HETEROARYL- N-CARBONYLBENZENESULFONAMIDES TARGETING DRUGGABLE HUMAN CARBONIC ANHYDRASE ISOFORMS (HCA VII, HCA IX, AND HCA XIV)  |   LYASE, CARBONATE DEHYDRATASE II, CARBONIC ANHYDRASE C, CARBONIC ANHYDRASE II, CA-II, CARBONATE DEHYDRATASE II- INHIBITOR COMPLEX 
4z1k:A   (ALA115) to   (LEU211)  CARBONIC ANHYDRASE INHIBITORS: DESIGN AND SYNTHESIS OF NEW HETEROARYL- N-CARBONYLBENZENESULFONAMIDES TARGETING DRUGGABLE HUMAN CARBONIC ANHYDRASE ISOFORMS (HCA VII, HCA IX, AND HCA XIV)  |   LYASE, CARBONATE DEHYDRATASE II, CARBONIC ANHYDRASE C, CARBONIC ANHYDRASE II, CA-II, CARBONATE DEHYDRATASE II- INHIBITOR COMPLEX 
4z1n:A   (ALA115) to   (LEU211)  CARBONIC ANHYDRASE INHIBITORS: DESIGN AND SYNTHESIS OF NEW HETEROARYL- N-CARBONYLBENZENESULFONAMIDES TARGETING DRUGGABLE HUMAN CARBONIC ANHYDRASE ISOFORMS (HCA VII, HCA IX, AND HCA XIV)  |   LYASE, CARBONATE DEHYDRATASE II, CARBONIC ANHYDRASE C, CARBONIC ANHYDRASE II, CA-II, CARBONATE DEHYDRATASE II- INHIBITOR COMPLEX 
1g3z:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II (F131V)  |   CARBONIC ANHYDRASE II, F131V, LYASE 
1g45:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4- (AMINOSULFONYL)-N-[(2-FLUOROPHENYL)METHYL]-BENZAMIDE  |   CARBONIC ANHYDRASE II, F131V, 4-(AMINOSULFONYL)-N-[(2- FLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
1g4o:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4- (AMINOSULFONYL)-N-PHENYLMETHYLBENZAMIDE  |   CARBONIC ANHYDRASE II, F131V, 4-(AMINOSULFONYL)-N- PHENYLMETHYLBENZAMIDE, LYASE 
1g52:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEXED WITH 4-(AMINOSULFONYL)-N- [(2,3-DIFLUOROPHENYL)METHYL]-BENZAMIDE  |   CARBONIC ANHYDRASE II, 4-(AMINOSULFONYL)-N-[(2,3- DIFLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
1g53:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEXED WITH 4-(AMINOSULFONYL)-N- [(2,6-DIFLUOROPHENYL)METHYL]-BENZAMIDE  |   CARBONIC ANHYDRASE II, 4-(AMINOSULFONYL)-N-[(2,6- DIFLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
1g54:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEXED WITH 4-(AMINOSULFONYL)-N- [(2,3,4,5,6-PENTAFLUOROPHENYL)METHYL]-BENZAMIDE  |   CARBONIC ANHYDRASE II, 4-(AMINOSULFONYL)-N-[(2,3,4,5,6- PENTAFLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
1g6v:A   (ALA115) to   (LEU212)  COMPLEX OF THE CAMELID HEAVY-CHAIN ANTIBODY FRAGMENT CAB- CA05 WITH BOVINE CARBONIC ANHYDRASE  |   ANTIBODY, ANTIGEN, COMPLEX, IMMUNOGLOBULIN, LYASE/IMMUNE SYSTEM COMPLEX 
1rzb:A   (ALA115) to   (LEU212)  X-RAY ANALYSIS OF METAL SUBSTITUTED HUMAN CARBONIC ANHYDRASE II DERIVATIVES  |   LYASE(OXO-ACID) 
1rzc:A   (ALA115) to   (LEU212)  X-RAY ANALYSIS OF METAL SUBSTITUTED HUMAN CARBONIC ANHYDRASE II DERIVATIVES  |   LYASE(OXO-ACID) 
1rzd:A   (ALA115) to   (LEU212)  X-RAY ANALYSIS OF METAL SUBSTITUTED HUMAN CARBONIC ANHYDRASE II DERIVATIVES  |   LYASE(OXO-ACID) 
1rze:A   (ALA115) to   (LEU212)  X-RAY ANALYSIS OF METAL SUBSTITUTED HUMAN CARBONIC ANHYDRASE II DERIVATIVES  |   LYASE(OXO-ACID) 
2fmg:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE ACTIVATORS. ACTIVATION OF ISOFORMS I, II, IV, VA, VII AND XIV WITH L- AND D- PHENYLALANINE AND CRYSTALLOGRAPHIC ANALYSIS OF THEIR ADDUCTS WITH ISOZYME II: STEROSPECIFIC RECOGNITION WITHIN THE ACTIVE SITE OF AN ENZYME AND ITS CONSEQUENCES FOR THE DRUG DESIGN, STRUCTURE WITH L-PHENYLALANINE  |   CARBONIC ANHYDRASE II, ACTIVATORS, LYASE 
2fmz:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE ACTIVATORS. ACTIVATION OF ISOFORMS I, II, IV, VA, VII AND XIV WITH L- AND D- PHENYLALANINE, STRUCTURE WITH D-PHENYLALANINE.  |   CARBONIC ANHYDRASE, ACTIVATORS, CRYSTAL STRUCTURE, LYASE 
2fnk:A   (ALA115) to   (LEU212)  ACTIVATION OF HUMAN CARBONIC ANHYDRASE II BY EXOGENOUS PROTON DONORS  |   CARBONIC ANHYDRASE, PROTON TRANSFER, EXOGENOUS PROTON DONOR, LYASE 
2fnm:A   (ALA115) to   (LEU212)  ACTIVATION OF HUMAN CARBONIC ANHDYRASE II BY EXOGENOUS PROTON DONORS  |   CARBONIC ANHYDRASE, PROTON TRANSFER, EXOGENOUS PROTON DONOR, LYASE 
2fnn:A   (ALA115) to   (LEU212)  ACTIVATION OF HUMAN CARBONIC ANHYDRASE II BY EXOGENOUS PROTON DONORS  |   CARBONIC ANHYDRASE, PROTON TRANSFER, EXOGENOUS PROTON DONOR, LYASE 
3hs4:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH ACETAZOLAMIDE  |   CARBONIC ANHYDRASE 2, CARBONIC ANHYDRASE II, LYASE, CA II, CA 2, ACETAZOLAMIDE, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, DISEASE MUTATION, METAL-BINDING 
2foq:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH TWO-PRONG INHIBITORS  |   LYASE, INHIBITOR 
2fos:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH TWO-PRONG INHIBITORS  |   LYASE, ZINC, INHIBITOR, COPPER 
2fou:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH TWO-PRONG INHIBITORS  |   LYASE, INHIBITOR 
2fov:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH TWO-PRONG INHIBITORS  |   LYASE, ZINC, INHIBITOR, COPPER 
2foy:A   (SER115) to   (CYS212)  HUMAN CARBONIC ANHYDRASE I COMPLEXED WITH A TWO-PRONG INHIBITOR  |   LYASE, ZINC, INHIBITOR, COPPER 
2foy:B   (SER115) to   (CYS212)  HUMAN CARBONIC ANHYDRASE I COMPLEXED WITH A TWO-PRONG INHIBITOR  |   LYASE, ZINC, INHIBITOR, COPPER 
3v2j:A   (ALA115) to   (LEU212)  EFFECT OF SUCROSE AND GLYCEROL AS CRYOPROTECTANS, ON THE INHIBITION OF HUMAN CARBONIC ANHYDRASE II  |   GLYCEROL, SUCROSE, CRYOPROTECTANT, ACETAZOLAMIDE, HCA II, LYASE 
3v2m:A   (ALA115) to   (LEU212)  EFFECT OF SUCROSE AND GLYCEROL AS CRYOPROTECTANS, ON THE INHIBITION OF HUMAN CARBONIC ANHYDRASE II  |   GLYCEROL, SUCROSE, CRYOPROTECTANT, ACETAZOLAMIDE, HCA II, LYASE 
4knn:B   (ALA117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH 2- CHLORO-4-[(PYRIMIDIN-2-YLSULFANYL)ACETYL]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4knn:A   (ALA117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH 2- CHLORO-4-[(PYRIMIDIN-2-YLSULFANYL)ACETYL]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4knm:A   (ALA117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH 2- CHLORO-4-{[(4,6-DIMETHYLPYRIMIDIN-2-YL) SULFANYL]ACETYL}BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4knm:B   (ALA117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH 2- CHLORO-4-{[(4,6-DIMETHYLPYRIMIDIN-2-YL) SULFANYL]ACETYL}BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3v3g:B   (ALA115) to   (LEU212)  KINETIC AND STRUCTURAL STUDIES OF THERMOSTABILIZED MUTANTS OF HCA II.  |   THERMOSTABILE, LYASE 
3v3h:B   (ALA115) to   (LEU212)  KINETIC AND STRUCTURAL STUDIES OF THERMOSTABILIZED MUTANTS OF HCA II.  |   THERMOSTABILE, LYASE 
3v3i:B   (ALA115) to   (LEU212)  KINETIC AND STRUCTURAL STUDIES OF THERMOSTABILIZED MUTANTS OF HCA II.  |   THERMOSTABILE, LYASE 
3v3j:A   (ALA115) to   (LEU212)  KINETIC AND STRUCTURAL STUDIES OF THERMOSTABILIZED MUTANTS OF HCA II.  |   THERMOSTABILE, LYASE 
2fw4:A   (SER115) to   (CYS212)  CARBONIC ANHYDRASE ACTIVATORS. THE FIRST X-RAY CRYSTALLOGRAPHIC STUDY OF AN ACTIVATOR OF ISOFORM I, STRUCTURE WITH L-HISTIDINE.  |   CARBONIC ANHYDRASE I, ACTIVATORS, CRYSTAL STRUCTURE, LYASE 
2fw4:B   (SER115) to   (CYS212)  CARBONIC ANHYDRASE ACTIVATORS. THE FIRST X-RAY CRYSTALLOGRAPHIC STUDY OF AN ACTIVATOR OF ISOFORM I, STRUCTURE WITH L-HISTIDINE.  |   CARBONIC ANHYDRASE I, ACTIVATORS, CRYSTAL STRUCTURE, LYASE 
3v5g:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH THE 4-SULFAMIDO-BENZENESULFONAMIDE INHIBITOR  |   LYASE-LYASE INHIBITOR COMPLEX 
3v7x:A  (ALA1115) to  (LEU1212)  COMPLEX OF HUMAN CARBONIC ANHYDRASE II WITH N-[2-(3,4- DIMETHOXYPHENYL)ETHYL]-4-SULFAMOYLBENZAMIDE  |   LYASE-LYASE INHIBITOR COMPLEX 
3vbd:A  (ALA1115) to  (LEU1212)  COMPLEX OF HUMAN CARBONIC ANHYDRASE II WITH 4-(6-METHOXY-3,4- DIHYDROISOQUINOLIN-1-YL)BENZENESULFONAMIDE  |   LYASE-LYASE INHIBITOR COMPLEX 
4kuv:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH THE 5-(3-(4-CHLOROPHENYLSULFONYL)UREIDO)PYRIDINE-2-SULFONAMIDE INHIBITOR  |   LYASE, LYASE-LYASE INHIBITOR COMPLEX 
4kuw:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH THE 5-(3-(4-FLUOROPHENYLSULFONYL)UREIDO)PYRIDINE-2-SULFONAMIDE INHIBITOR  |   LYASE, LYASE-LYASE INHIBITOR COMPLEX 
4kv0:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH THE 5-(3-TOSYLUREIDO)PYRIDINE-2-SULFONAMIDE INHIBITOR  |   LYASE, LYASE-LYASE INHIBITOR COMPLEX 
2vva:X   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE IN COMPLEX WITH CO2  |   METAL-BINDING, CARBON DIOXIDE, DISEASE MUTATION, SUBSTRATE BINDING, CARBONIC ANHYDRASE, ZINC, LYASE, CYTOPLASM, ACETYLATION, POLYMORPHISM 
2vvb:X   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BICARBONATE  |   POLYMORPHISM, METAL-BINDING, DISEASE MUTATION, ZINC, LYASE, CYTOPLASM, ACETYLATION, BICARBONATE, SUBSTRATE BINDING, CARBONIC ANHYDRASE 
2gd8:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE ANALYSIS OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A 2-SUBSTITUTED ESTRADIOL BIS-SULFAMATE  |   PROTEIN-INHIBITOR COMPLEXES, LYASE 
3ibi:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH AN ALIPHATIC SULFAMATE INHIBITOR  |   CARBONIC ANHYDRASE II, PROTEIN-INHIBITOR COMPLEX, ALIPHATIC SULFAMATE INHIBITOR, DISEASE MUTATION, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3ibn:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH AN ALIPHATIC BIS-SULFAMATE INHIBITOR  |   CARBONIC ANHYDRASE II, PROTEIN-INHIBITOR COMPLEX, ALIPHATIC BIS- SULFAMATE INHIBITOR, DISEASE MUTATION, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3ibu:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH AN ALIPHATIC SULFAMATE INHIBITOR  |   CARBONIC ANHYDRASE II, PROTEIN-INHIBITOR COMPLEX, ALIPHATIC SULFAMATE INHIBITOR, DISEASE MUTATION, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4l5u:A   (ALA115) to   (LEU212)  THE STRUCTURAL IMPLICATIONS OF THE SECONDARY CO2 BINDING POCKET IN HUMAN CARBONIC ANHYDRASE II  |   ALLOSTERIC REGULATION, THERMOSTABILITY, LYASE 
4l5v:A   (ALA115) to   (LEU212)  THE STRUCTURAL IMPLICATIONS OF THE SECONDARY CO2 BINDING POCKET IN HUMAN CARBONIC ANHYDRASE II  |   ALLOSTERIC REGULATION, THERMOSTABILITY, LYASE 
1h4n:A   (ALA115) to   (LEU212)  H94N CARBONIC ANHYDRASE II COMPLEXED WITH TRIS  |   LYASE, OXO-ACID, ACETYLATION 
3ieo:A   (ALA115) to   (LEU212)  THE COUMARIN-BINDING SITE IN CARBONIC ANHYDRASE: THE ANTIEPILEPTIC LACOSAMIDE AS AN EXAMPLE  |   CARBONIC ANHYDRASE, ANTIEPILECTIC, DISEASE MUTATION, LYASE, METAL- BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3igp:A   (ALA115) to   (LEU212)  STRUCTURE OF INHIBITOR BINDING TO CARBONIC ANHYDRASE II  |   CARBONIC ANHYDRASE INHIBITORS, ISOQUINOLINES, LYASE, ACETYLATION, CYTOPLASM, DISEASE MUTATION, METAL-BINDING, POLYMORPHISM, ZINC 
1t9n:A   (ALA115) to   (LEU212)  EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II  |   PROTON SHUTTLE, CARBONIC ANHYDRASE, METALLOENZYME, LYASE 
1h9q:A   (ALA115) to   (LEU212)  H119Q CARBONIC ANHYDRASE II  |   LYASE, OXO-ACID, ACETYLATION 
1tb0:X   (ALA115) to   (LEU212)  EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II  |   PROTON SHUTTLE CARBONIC ANHYDRASE METALLOENZYME, LYASE 
1tbt:X   (ALA115) to   (LEU212)  EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II  |   PROTON SHUTTLE CARBONIC ANHYDRASE METALLOENZYME, LYASE 
1te3:X   (ALA115) to   (LEU212)  EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II  |   PROTON SHUTTLE CARBONIC ANHYDRASE METALLOENZYME, LYASE 
1teq:X   (ALA115) to   (LEU212)  EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II  |   PROTON SHUTTLE CARBONIC ANHYDRASE METALLOENZYME, LYASE 
1teu:X   (ALA115) to   (LEU212)  EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II  |   PROTON SHUTTLE CARBONIC ANHYDRASE METALLOENZYME, LYASE 
1hca:A   (ALA115) to   (LEU212)  UNEXPECTED PH-DEPENDENT CONFORMATION OF HIS-64, THE PROTON SHUTTLE OF CARBONIC ANHYDRASE II.  |   LYASE(OXO-ACID) 
1hcb:A   (SER115) to   (CYS212)  ENZYME-SUBSTRATE INTERACTIONS: STRUCTURE OF HUMAN CARBONIC ANHYDRASE I COMPLEXED WITH BICARBONATE  |   LYASE(OXO-ACID) 
1tg9:A   (ALA115) to   (LEU212)  EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II  |   PROTON SHUTTLE CARBONIC ANHYDRASE METALLOENZYME, LYASE 
1heb:A   (ALA115) to   (LEU212)  STRUCTURAL CONSEQUENCES OF HYDROPHILIC AMINO-ACID SUBSTITUTIONS IN THE HYDROPHOBIC POCKET OF HUMAN CARBONIC ANHYDRASE II  |   LYASE(OXO-ACID) 
1th9:A   (ALA115) to   (LEU212)  EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II  |   PROTON SHUTTLE CARBONIC ANHYDRASE METALLOENZYME, LYASE 
1thk:A   (ALA115) to   (LEU212)  EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II  |   PROTON SHUTTLE CARBONIC ANHYDRASE METALLOENZYME, LYASE 
4lhi:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 5- (PHENYLSULFONYL)THIOPHENE-2-SULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
2h4n:A   (ALA115) to   (LEU212)  H94N CARBONIC ANHYDRASE II COMPLEXED WITH ACETAZOLAMIDE  |   LYASE, OXO-ACID, ACETYLATION 
4zwy:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A GLUCOSYL SULFAMATE INHIBITOR  |   CARBONIC ANHYDRASE II, GLUCOSYL SULFAMATE, INHIBITOR COMPLEX., LYASE- LYASE INHIBITOR COMPLEX 
4zwz:A   (ALA115) to   (LEU212)  ENGINEERED CARBONIC ANHYDRASE IX MIMIC IN COMPLEX WITH A GLUCOSYL SULFAMATE INHIBITOR  |   CARBONIC ANHYDRASE IX MIMIC, GLUCOSYL SULFAMATE, INHIBITOR COMPLEX., LYASE-LYASE INHIBITOR COMPLEX 
4zx0:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A GLUCOSYL SULFAMATE INHIBITOR  |   CARBONIC ANHYDRASE II, GLUCOSYL SULFAMATE, INHIBITOR COMPLEX., LYASE- LYASE INHIBITOR COMPLEX 
2wd3:A   (ALA115) to   (LEU211)  HIGHLY POTENT FIRST EXAMPLES OF DUAL AROMATASE-STEROID SULFATASE INHIBITORS BASED ON A BIPHENYL TEMPLATE  |   HUMAN CARBONIC ANHYDRASE INHIBITOR, LYASE, CANCER, BIPHENYL, TRIAZOLE, DUAL AROMATASE-STEROID SULFATASE INHIBITOR, SULFAMATE, METAL-BINDING 
2hd6:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A HYPOXIA-ACTIVATABLE SULFONAMIDE.  |   PROTEIN-INHIBITOR COMPLEX, LYASE 
2weg:A   (ALA115) to   (LEU212)  THERMODYNAMIC OPTIMISATION OF CARBONIC ANHYDRASE FRAGMENT INHIBITORS  |   METAL-BINDING, DISEASE MUTATION, LYASE, ZINC, CYTOPLASM, ACETYLATION, POLYMORPHISM 
2weh:A   (ALA115) to   (LEU212)  THERMODYNAMIC OPTIMISATION OF CARBONIC ANHYDRASE FRAGMENT INHIBITORS  |   METAL-BINDING, DISEASE MUTATION, LYASE, ZINC, CYTOPLASM, ACETYLATION, POLYMORPHISM 
2wej:A   (ALA115) to   (LEU212)  THERMODYNAMIC OPTIMISATION OF CARBONIC ANHYDRASE FRAGMENT INHIBITORS  |   METAL-BINDING, DISEASE MUTATION, ZINC, LYASE, CYTOPLASM, ACETYLATION, POLYMORPHISM 
2weo:A   (ALA115) to   (LEU212)  THERMODYNAMIC OPTIMISATION OF CARBONIC ANHYDRASE FRAGMENT INHIBITORS  |   METAL-BINDING, DISEASE MUTATION, ZINC, LYASE, CYTOPLASM, ACETYLATION, POLYMORPHISM 
1ttm:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH 667-COUMATE  |   CANCER, HUMAN CARBONIC ANHYDRASE INHIBITORS, 667-COUMATE, OBESITY, STEROID SULFATASE INHIBITOR, LYASE 
2hkk:A   (ALA115) to   (LEU211)  CARBONIC ANHYDRASE ACTIVATORS: SOLUTION AND X-RAY CRYSTALLOGRAPHY FOR THE INTERACTION OF ANDRENALINE WITH VARIOUS CARBONIC ANHYDRASE ISOFORMS  |   CARBONIC ANHYDRASE, ACTIVATORS, LYASE 
2hl4:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE ANALYSIS OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A BENZENESULFONAMIDE DERIVATIVE  |   PROTEIN-INHIBITOR COMPLEX, LYASE 
1hug:A   (SER115) to   (CYS212)  DIFFERENCES IN ANIONIC INHIBITION OF HUMAN CARBONIC ANHYDRASE I REVEALED FROM THE STRUCTURES OF IODIDE AND GOLD CYANIDE INHIBITOR COMPLEXES  |   LYASE(OXO-ACID) 
2hoc:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH THE 5-(4-AMINO-3-CHLORO-5-FLUOROPHENYLSULFONAMIDO)-1,3,4-THIADIAZOLE- 2-SULFONAMIDE INHIBITOR  |   PROTEIN-INHIBITOR COMPLEX, LYASE 
5a25:A   (ALA115) to   (LEU211)  RATIONAL ENGINEERING OF A MESOPHILIC CARBONIC ANHYDRASE TO AN EXTREME HALOTOLERANT BIOCATALYST  |   LYASE, PROTEIN ENGINEERING, BIOCATALYSIS 
5a25:B   (ALA115) to   (LEU211)  RATIONAL ENGINEERING OF A MESOPHILIC CARBONIC ANHYDRASE TO AN EXTREME HALOTOLERANT BIOCATALYST  |   LYASE, PROTEIN ENGINEERING, BIOCATALYSIS 
1i90:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEXED WITH AL-8520 2H-THIENO[3,2- E]-1,2-THIAZINE-6-SULFONAMIDE, 4-AMINO-3,4-DIHYDRO-2-(3- METHOXYPROPYL)-, 1,1-DIOXIDE, (R)  |   CARBONIC ANHYDRASE II, AL-8520, LYASE 
1i91:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEXED WITH AL-6619 2H-THIENO[3,2- E]-1,2-THIAZINE-6-SULFONAMIDE, 2-(3-HYDROXYPHENYL)-3-(4- MORPHOLINYL)-, 1,1-DIOXIDE  |   CARBONIC ANHYDRASE II, AL-6619, LYASE 
1i9l:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4- (AMINOSULFONYL)-N-[(4-FLUOROPHENYL)METHYL]-BENZAMIDE  |   HUMAN CARBONIC ANHYDRASE II, 4-(AMINOSULFONYL)-N-[(4- FLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
1i9m:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4- (AMINOSULFONYL)-N-[(2,4-DIFLUOROPHENYL)METHYL]-BENZAMIDE  |   HUMAN CARBONIC ANHYDRASE II, 4-(AMINOSULFONYL)-N-[(2,4- DIFLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
1i9n:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4- (AMINOSULFONYL)-N-[(2,5-DIFLUOROPHENYL)METHYL]-BENZAMIDE  |   HUMAN CARBONIC ANHYDRASE II, 4-(AMINOSULFONYL)-N-[(2,5- DIFLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
1i9o:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4- (AMINOSULFONYL)-N-[(2,3,4-TRIFLUOROPHENYL)METHYL]-BENZAMIDE  |   HUMAN CARBONIC ANHYDRASE II, 4-(AMINOSULFONYL)-N-[(2,3,4- TRIFLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
1i9p:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4- (AMINOSULFONYL)-N-[(2,4,6-TRIFLUOROPHENYL)METHYL]-BENZAMIDE  |   HUMAN CARBONIC ANHYDRASE II, 4-(AMINOSULFONYL)-N-[(2,4,6- TRIFLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
1i9q:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4- (AMINOSULFONYL)-N-[(3,4,5-TRIFLUOROPHENYL)METHYL]-BENZAMIDE  |   HUMAN CARBONIC ANHYDRASE II, 4-(AMINOSULFONYL)-N-[(3,4,5- TRIFLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
1if4:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEXED WITH 4- FLUOROBENZENESULFONAMIDE  |   CARBONIC ANHYDRASE II, 4-FLUOROBENZENESULFONAMIDE, LYASE 
1if5:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEXED WITH 2,6- DIFLUOROBENZENESULFONAMIDE  |   CARBONIC ANHYDRASE II, 2,6-DIFLUOROBENZENESULFONAMIDE, LYASE 
1if6:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEXED WITH 3,5- DIFLUOROBENZENESULFONAMIDE  |   CARBONIC ANHYDRASE II, 3,5-DIFLUOROBENZENESULFONAMIDE, LYASE 
1if7:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEXED WITH (R)-N-(3-INDOL-1-YL-2- METHYL-PROPYL)-4-SULFAMOYL-BENZAMIDE  |   CARBONIC ANHYDRASE II, (R)-N-(3-INDOL-1-YL-2-METHYL-PROPYL)- 4-SULFAMOYL-BENZAMIDE, LYASE 
1if8:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEXED WITH (S)-N-(3-INDOL-1-YL-2- METHYL-PROPYL)-4-SULFAMOYL-BENZAMIDE  |   CARBONIC ANHYDRASE II, (S)-N-(3-INDOL-1-YL-2-METHYL-PROPYL)- 4-SULFAMOYL-BENZAMIDE, LYASE 
1if9:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEXED WITH N-[2-(1H-INDOL-5-YL)- BUTYL]-4-SULFAMOYL-BENZAMIDE  |   CARBONIC ANHYDRASE II, N-[2-(1H-INDOL-5-YL)-BUTYL]-4- SULFAMOYL-BENZAMIDE, LYASE 
1uga:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY PHE (A65F)  |   LYASE (OXO-ACID), ACETYLATION, ZINC, POLYMORPHISM, DISEASE MUTATION 
1ugc:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY HIS (A65H)  |   LYASE, ACETYLATION, ZINC, POLYMORPHISM, DISEASE MUTATION 
1ugd:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY SER (A65S)  |   LYASE (OXO-ACID), ACETYLATION, ZINC, POLYMORPHISM, DISEASE MUTATION 
1uge:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY LEU (A65L)  |   LYASE, ACETYLATION, ZINC, POLYMORPHISM, DISEASE MUTATION 
1ugf:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY THR (A65T)  |   LYASE, ACETYLATION, ZINC, POLYMORPHISM, DISEASE MUTATION 
1ugg:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY SER (A65S)-ORTHORHOMBIC FORM  |   LYASE (OXO-ACID), ACETYLATION, ZINC, POLYMORPHISM, DISEASE MUTATION 
5a6h:A   (ALA115) to   (LEU212)  SYNTHESIS, CARBONIC ANHYDRASE INHIBITION AND PROTEIN X-RAY STRUCTURE OF THE UNUSUAL NATURAL PRODUCT PRIMARY SULFONAMIDE PSAMMAPLIN C  |   LYASE, CARBONIC ANHYDRASE INHIBITOR, NATURAL PRODUCT 
4m2r:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BRINZOLAMIDE  |   LYASE-LYASE INHIBITOR COMPLEX 
4m2v:A   (ALA115) to   (LEU212)  GENETICALLY ENGINEERED CARBONIC ANHYDRASE IX IN COMPLEX WITH BRINZOLAMIDE  |   CARBONIC ANHYDRASE IX MIMIC, LYASE-LYASE INHIBITOR COMPLEX 
4m2w:A   (ALA115) to   (LEU212)  GENETICALLY ENGINEERED CARBONIC ANHYDRASE IX IN COMPLEX WITH DORZOLAMIDE  |   CARBONIC ANHYDRASE IX MIMIC, LYASE-LYASE INHIBITOR COMPLEX 
1urt:A   (PRO115) to   (GLN212)  MURINE CARBONIC ANHYDRASE V  |   LYASE, ZINC, MITOCHONDRION, TRANSIT PEPTIDE 
4mdg:A   (ALA115) to   (LEU212)  CLOSO CARBORANE CARBONIC ANHYDRASE INHIBITOR  |   CARBONIC ANHYDRASE INHIBITOR COMPLEX, LYASE-LYASE INHIBITOR COMPLEX 
4mdm:A   (ALA115) to   (LEU212)  NIDO-CARBORANE CARBONIC ANHYDRASE INHIBITOR  |   CARBONIC ANHYDRASE INHIBITOR COMPLEX, LYASE-LYASE INHIBITOR COMPLEX 
2ili:A   (ALA115) to   (LEU212)  REFINE ATOMIC STRUCTURE OF HUMAN CARBONIC ANHYDRASE II  |   PROTON TRANSFER, PROTON SHUTTLE, CARBONIC ANHYDRASE, LYASE 
2it4:A   (SER115) to   (CYS212)  X RAY STRUCTURE OF THE COMPLEX BETWEEN CARBONIC ANHYDRASE I AND THE PHOSPHONATE ANTIVIRAL DRUG FOSCARNET  |   CARBONIC ANHYDRASE, ANTIVIRAL, CRYSTAL STUCTURE, LYASE 
5amd:A   (ALA115) to   (LEU212)  THREE DIMENSIONAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 2-((2-PHENYLETHYL)SULFAMOYL)-4-SULFAMOYLBENZOIC ACID  |   LYASE, CA II, CA 2 
5amg:A   (ALA115) to   (LEU212)  THREE DIMENSIONAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 2-(PENTYLSULFAMOYL)-4-SULFAMOYLBENZOIC ACID  |   LYASE, CA II, CA 2 
5aml:A   (ALA115) to   (LEU212)  THREE DIMENSIONAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 2-(BUT-2-YN-1-YLSULFAMOYL)-4-SULFAMOYLBENZOIC ACID  |   LYASE, CA II, CA 2 
4mlt:A   (ALA115) to   (LEU212)  STRUCTURE OF A MONODENTATE 3-HYDROXY-4H-PYRAN-4-THIONE LIGAND BOUND TO HCAII  |   LYASE 
4mlx:A   (ALA115) to   (LEU212)  STRUCTURE OF A BIDENTATE 3-HYDROXY-4H-PYRAN-4-THIONE LIGAND BOUND TO HCAII  |   LYASE 
1v9i:C   (ALA116) to   (LEU212)  CRYSTAL STRUCTURE ANALYSIS OF THE SITE SPECIFIC MUTANT (Q253C) OF BOVINE CARBONIC ANHYDRASE II  |   BETA SHEET, ZINC METALLOENZYME, LYASE 
4mo8:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH N-[2-(2-METHYL-5-NITRO-1H-IMIDAZOL-1-YL)ETHYL]SULFAMIDE  |   SULFAMIDE, ZINC BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4mty:A   (ALA115) to   (LEU211)  STRUCTURE AT 2.1 A REOLUTION OF A HELICAL AROMATIC FOLDAMER-PROTEIN COMPLEX.  |   MIXED ALPHA BETA, LYASE-LYASE INHIBITOR COMPLEX 
4n0x:B   (ALA115) to   (LEU212)  ROOM TEMPERATURE CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH THIOPHENE-2-SULFONAMIDE  |   MIXED ALPHA/BETA, CARBONATE DEHYDRATASE, CYTOSOLIC, LYASE 
4n16:A   (ALA115) to   (LEU212)  STRUCTURE OF CHOLATE BOUND TO HUMAN CARBONIC ANHYDRASE II  |   CHOLATE, CHOLIC ACID, LYASE 
5bnl:A   (ALA115) to   (LEU212)  DECIPHERING THE MECHANISM OF CARBONIC ANHYDRASE INHIBITION WITH COUMARINS AND THIOCOUMARINS  |   HCA2, COUMARIN, INHIBITORS, LYASE 
5bru:A   (ALA115) to   (LEU211)  CATALYTIC IMPROVEMENT OF AN ARTIFICIAL METALLOENZYME BY COMPUTATIONAL DESIGN  |   ARTIFICIAL METALLOENZYME, OXIDOREDUCTASE 
5brv:A   (ALA115) to   (LEU211)  CATALYTIC IMPROVEMENT OF AN ARTIFICIAL METALLOENZYME BY COMPUTATIONAL DESIGN  |   ARTIFICIAL METALLOENZYME, OXIDOREDUCTASE 
5brw:A   (ALA115) to   (LEU211)  CATALYTIC IMPROVEMENT OF AN ARTIFICIAL METALLOENZYME BY COMPUTATIONAL DESIGN  |   ARTIFICIAL METALLOENZYME, LYASE, IMINE REDUCTASE, TRANSFER HYDROGENASE, OXIDOREDUCTASE 
5byi:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II WITH AN AZOBENZENE INHIBITOR (1D)  |   CARBONIC ANHYDRASE, SULFONAMIDE, PHOTOPHARMACOLOGY, INHIBITOR, LYASE 
1keq:A   (PRO115) to   (GLN212)  CRYSTAL STRUCTURE OF F65A/Y131C CARBONIC ANHYDRASE V, COVALENTLY MODIFIED WITH 4-CHLOROMETHYLIMIDAZOLE  |   PROTON TRANSFER, ENGINEERED RESIDUE, LYASE 
1keq:B   (PRO115) to   (GLN212)  CRYSTAL STRUCTURE OF F65A/Y131C CARBONIC ANHYDRASE V, COVALENTLY MODIFIED WITH 4-CHLOROMETHYLIMIDAZOLE  |   PROTON TRANSFER, ENGINEERED RESIDUE, LYASE 
3zp9:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II AS A SCAFFOLD FOR AN ARTIFICIAL TRANSFER HYDROGENASE  |   ARTIFICIAL METALLOENZYME, LYASE, INHIBITOR, IRIDIUM PENTAMETHYLCYCLOPENTADIENYL, PIANO STOOL COMPLEX 
1kwq:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH INHIBITOR 2000-07  |   LYASE, ZINC, INHIBITOR 
1kwr:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH INHIBITOR 0134-36  |   LYASE, ZINC, INHIBITOR 
5c8i:A   (ALA115) to   (LEU212)  JOINT X-RAY/NEUTRON STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH METHAZOLAMIDE  |   METHAZOLAMIDE, ACETAZOLAMIDE, WATER DISPLACEMENT, LYASE 
2nmx:A   (SER115) to   (CYS212)  STRUCTURE OF INHIBITOR BINDING TO CARBONIC ANHYDRASE I  |   METALLOENZYME, HYDRO LYASE, LYASE 
2nn1:A   (SER115) to   (CYS212)  STRUCTURE OF INHIBITOR BINDING TO CARBONIC ANHYDRASE I  |   ZINC METALLOENZYME, LYASE 
2nn1:B   (SER115) to   (CYS212)  STRUCTURE OF INHIBITOR BINDING TO CARBONIC ANHYDRASE I  |   ZINC METALLOENZYME, LYASE 
2nn7:A   (SER115) to   (CYS212)  STRUCTURE OF INHIBITOR BINDING TO CARBONIC ANHYDRASE I  |   ZINC METALLOENZYME, LYASE 
2nn7:B   (SER115) to   (CYS212)  STRUCTURE OF INHIBITOR BINDING TO CARBONIC ANHYDRASE I  |   ZINC METALLOENZYME, LYASE 
2nng:A   (ALA115) to   (LEU212)  STRUCTURE OF INHIBITOR BINDING TO CARBONIC ANHYDRASE II  |   ZINC METALLOENZYME, SULFONAMIDE, LYASE 
2nno:A   (ALA115) to   (LEU212)  STRUCTURE OF INHIBITOR BINDING TO CARBONIC ANHYDRASE II  |   ZINC METALLOENZYME, SULFONAMIDE, LYASE 
2nns:A   (ALA115) to   (LEU212)  STRUCTURE OF INHIBITOR BINDING TO CARBONIC ANHYDRASE II  |   ZINC METALLOENZYME, SULFONAMIDE, LYASE 
1xev:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN A NEW CRYSTAL FORM  |   HUMAN CARBONIC ANHYDRASE II, TRANSLATIONAL SYMMETRY, X-RAY STRUCTURE, LYASE 
1xev:C   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN A NEW CRYSTAL FORM  |   HUMAN CARBONIC ANHYDRASE II, TRANSLATIONAL SYMMETRY, X-RAY STRUCTURE, LYASE 
1xev:D   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN A NEW CRYSTAL FORM  |   HUMAN CARBONIC ANHYDRASE II, TRANSLATIONAL SYMMETRY, X-RAY STRUCTURE, LYASE 
5ca2:A   (ALA115) to   (LEU212)  CONFORMATIONAL MOBILITY OF HIS-64 IN THE THR-200 (RIGHT ARROW) SER MUTANT OF HUMAN CARBONIC ANHYDRASE II  |   LYASE(OXO-ACID) 
5cac:A   (ALA115) to   (LEU212)  REFINED STRUCTURE OF HUMAN CARBONIC ANHYDRASE II AT 2.0 ANGSTROMS RESOLUTION  |   LYASE(OXO-ACID) 
3jxh:C   (PRO171) to   (PHE270)  CA-LIKE DOMAIN OF HUMAN PTPRG  |   CA-LIKE DOMAIN, ALTERNATIVE SPLICING, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PHOSPHOPROTEIN, POLYMORPHISM, PROTEIN PHOSPHATASE, TRANSMEMBRANE, CELL ADHESION 
2nwo:A   (ALA115) to   (LEU212)  STRUCTURAL AND KINETIC EFFECT OF HYDROPHOBIC MUTATIONS IN THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II  |   PROTON TRANSFER, HISTIDINE 64, CARBONIC ANHYDRASE, LYASE 
2nwp:A   (ALA115) to   (LEU212)  STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS IN THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II  |   PROTON TRANSFER, HISTIDINE 64, CARBONIC ANHYDRASE, LYASE 
2nwz:A   (ALA115) to   (LEU212)  STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS ON THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II  |   PROTON TRANSFER, HISTIDINE 64, CARBONIC ANHYDRASE, LYASE 
2nxr:A   (ALA115) to   (LEU212)  STRUCTURAL EFFECTS OF HYDROPHOBIC MUTATIONS ON THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II  |   PROTON TRANSFER, HISTIDINE 64, CARBONIC ANHYDRASE, LYASE 
2nxs:A   (ALA115) to   (LEU212)  STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS IN THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II  |   PROTON TRANSFER, HISTIDINE 64, CARBONIC ANHYDRASE, LYASE 
2nxt:A   (ALA115) to   (LEU211)  STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS IN THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II  |   PROTON TRANSFER, HISTIDINE 64, CARBONIC ANHYDRASE, LYASE 
5cjl:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A HETEROARYL-PYRAZOLE CARBOXYLIC ACID DERIVATIVE.  |   HUMAN CARBONIC ANHYDRASE II, INHIBITOR COMPLEX, CARBOXYLIC ACID., LYASE-LYASE INHIBITOR COMPLEX 
1lg5:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE ANALYSIS OF THE HCA II MUTANT T199P IN COMPLEX WITH BETA-MERCAPTOETHANOL  |   HCAII MUTANT T199P-BME COMPLEX, LYASE 
1lgd:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE ANALYSIS OF HCA II MUTANT T199P IN COMPLEX WITH BICARBONATE  |   HCAII MUTANT T199P-BCT COMPLEX, LYASE 
3k2f:A   (ALA115) to   (LEU212)  NITRIC OXIDE-DONATING CARBONIC ANHYDRASE INHIBITORS FOR THE TREATMENT OF OPEN-ANGLE GLAUCOMA  |   CARBONIC ANHYDRASE, NO-DONATING AGENT, ANTIGLAUCOMA DRUG, SULFONAMIDE, XRAY CRYSTALLOGRAPHY, LYASE, ACETYLATION, CYTOPLASM, DISEASE MUTATION, METAL-BINDING, POLYMORPHISM, ZINC 
5clu:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF THE COMPLEX OF HCAII WITH A SACCHARINE DERIVATIVE  |   CARBONIC ANHYDRASE II, LYASE 
2o4z:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE CARBONIC ANHYDRASE II COMPLEXED WITH HYDROXYSULFAMIDE INHIBITOR  |   CARBONIC ANHYDRASE, INHIBITORS, CRYSTAL STRUCTURE, LYASE 
1lug:A   (ALA115) to   (LEU211)  FULL MATRIX ERROR ANALYSIS OF CARBONIC ANHYDRASE  |   ERROR ANALYSIS, FULL-MATRIX, METALLOENZYME, LYASE 
1lzv:A   (ALA115) to   (LEU212)  SITE-SPECIFIC MUTANT (TYR7 REPLACED WITH HIS) OF HUMAN CARBONIC ANHYDRASE II  |   TWISTED BETA SHEET, ZINC METALLOENZYME, LYASE 
1xpz:A   (ALA115) to   (LEU212)  STRUCTURE OF HUMAN CARBONIC ANHYDRASE II WITH 4-[4-O- SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE  |   CARBONIC ANHYDRASE, DUAL AROMATASE-STEROID SULFATASE INHIBITOR (DASI), ANTI-CANCER DRUG DELIVERY, LYASE 
1xq0:A   (ALA115) to   (LEU212)  STRUCTURE OF HUMAN CARBONIC ANHYDRASE II WITH 4-[(3-BROMO-4- O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE  |   CARBONIC ANHYDRASE, DUAL AROMATASE-STEROID SULFATASE INHIBITOR (DASI), ANTI-CANCER DRUG DELIVERY, LYASE 
3kig:A   (ALA115) to   (LEU211)  MUTANT CARBONIC ANHYDRASE II IN COMPLEX WITH AN AZIDE AND AN ALKYNE  |   10 STRANDED, TWISTED BETA-SHEETS, LYASE, DISEASE MUTATION, METAL- BINDING 
3kkx:A   (ALA115) to   (LEU212)  NEUTRON STRUCTURE OF HUMAN CARBONIC ANHYDRASE II  |   PROTON TRANSFER, NEUTRON, HCA II, CYTOPLASM, LYASE, METAL- BINDING, ZINC 
3kne:A   (ALA115) to   (LEU211)  CARBONIC ANHYDRASE II H64C MUTANT IN COMPLEX WITH AN IN SITU FORMED TRIAZOLE  |   10 STRANDED; TWISTED BETA-SHEETS; LYASE; ACETYLATION, METAL-BINDING, CLICK-CHEMISTRY, AZIDE, ALKYNE, LYASE 
3koi:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF COBALT (III) HUMAN CARBONIC ANHYDRASE II AT PH 6.0  |   CARBONIC ANHYDRASE, METALLOENZYME, COBALT SUBSTITUTION, CRYSTAL PH, LYASE 
3kok:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF COBALT (II) HUMAN CARBONIC ANHYDRASE II AT PH 8.5  |   CARBONIC ANHYDRASE, METALLOENZYME, COBALT SUBSTITUTION, CRYSTAL PH, LYASE 
3kon:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF COBALT (II) HUMAN CARBONIC ANHYDRASE II AT PH 11.0  |   CARBONIC ANHYDRASE, METALLOENZYME, COBALT SUBSTITUTION, CRYSTAL PH, LYASE 
1moo:A   (ALA115) to   (LEU212)  SITE SPECIFIC MUTANT (H64A) OF HUMAN CARBONIC ANHYDRASE II AT HIGH RESOLUTION  |   HIGH-RESOLUTION, 4-METHYLIMIDAZOLE, TWISTED BETA SHEET, ZINC METALLOENZYME, LYASE 
1yda:A   (ALA115) to   (LEU212)  STRUCTURAL BASIS OF INHIBITOR AFFINITY TO VARIANTS OF HUMAN CARBONIC ANHYDRASE II  |   HYDRO-LYASE 
1ydb:A   (ALA115) to   (LEU212)  STRUCTURAL BASIS OF INHIBITOR AFFINITY TO VARIANTS OF HUMAN CARBONIC ANHYDRASE II  |   HYDRO-LYASE 
1mua:A   (ALA115) to   (LEU212)  STRUCTURE AND ENERGETICS OF A NON-PROLINE CIS-PEPTIDYL LINKAGE IN AN ENGINEERED PROTEIN  |   LYASE(OXO-ACID) 
3ks3:A   (ALA115) to   (LEU212)  HIGH RESOLUTION STRUCTURE OF HUMAN CARBONIC ANHYDRASE II AT 0.9 A  |   HIGH RESOLUTION, CARBONIC ANHYDRASE, SHORT HYDROGEN BOND 
3kwa:A   (ALA115) to   (LEU212)  POLYAMINES INHIBIT CARBONIC ANHYDRASES  |   POLYAMINES, CARBONIC ANHYDRASE II, INHIBITION, LYASE 
1yo2:A   (ALA115) to   (LEU212)  PROTON TRANSFER FROM HIS200 IN HUMAN CARBONIC ANHYDRASE II  |   PROTON TRANSFER HUMAN CARBONIC ANHYDRASE, LYASE 
5dog:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 2- (BENZYLAMINO)-3,5,6-TRIFLUORO-4-[(2-PHENYLETHYL)THIO]BENZENE- SULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, LYASE 
5doh:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 2-[(1S)- 2,3-DIHYDRO-1H-INDEN-1-YLAMINO]-3,5,6-TRIFLUORO-4-[(2-HYDROXYETHYL) THIO]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, LYASE 
5doh:B   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 2-[(1S)- 2,3-DIHYDRO-1H-INDEN-1-YLAMINO]-3,5,6-TRIFLUORO-4-[(2-HYDROXYETHYL) THIO]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, LYASE 
4pq7:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A SULFAMIDE INHIBITOR  |   SULFAMIDE, ZINC BINDING, LYASE-LYASE INHIBITOR COMPLEX 
1z97:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE III: STRUCTURAL AND KINETIC STUDY OF CATALYSIS AND PROTON TRANSFER.  |   CARBONIC ANHYDRASE, PROTON WIRE, CHEMICAL RESCUE, LYASE 
1z9y:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH FUROSEMIDE AS SULFONAMIDE INHIBITOR  |   10 STRANDED, TWISTED BETA-SHEETS, LYASE, LYASE-LYASE INHIBITOR COMPLEX 
5drs:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASEISOZYME II WITH 3-[(1S)- 2,3-DIHYDRO-1H-INDEN-1-YLAMINO]-2,5,6-TRIFLUORO-4-[(2-HYDROXYETHYL) SULFONYL]BENZENESULFONAMIDE  |   LYASE, DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL- BINDING, LYASE-LYASE INHIBITOR COMPLEX 
5dsi:A   (ALA115) to   (LEU212)  STRUCTURE OF CO2 BOUND HOLO-FORM OF HUMAN CARBONIC ANHYDRASE II WITH 0 SEC (NO) WARMING  |   CARBONIC ANHYDRASE II, CO2 RELEASE, INTERMEDIATE STATES, LYASE 
5dsk:A   (ALA115) to   (LEU212)  STRUCTURE OF CO2 RELEASED HOLO-FORM OF HUMAN CARBONIC ANHYDRASE II WITH 3 MIN WARMING  |   CARBONIC ANHYDRASE II, CO2 RELEASE, INTERMEDIATE STATES, LYASE 
5dsl:A   (ALA115) to   (LEU212)  STRUCTURE OF CO2 RELEASED HOLO-FORM OF HUMAN CARBONIC ANHYDRASE II WITH 10 MIN WARMING  |   CARBONIC ANHYDRASE II, CO2 RELEASE, INTERMEDIATE STATES, LYASE 
5dsm:A   (ALA115) to   (LEU212)  STRUCTURE OF CO2 RELEASED HOLO-FORM OF HUMAN CARBONIC ANHYDRASE II WITH 25 MIN WARMING  |   CARBONIC ANHYDRASE II, CO2 RELEASE, INTERMEDIATE STATES, LYASE 
5dsn:A   (ALA115) to   (LEU212)  STRUCTURE OF CO2 RELEASED HOLO-FORM OF HUMAN CARBONIC ANHYDRASE II WITH 1 HR WARMING  |   CARBONIC ANHYDRASE II, CO2 RELEASE, INTERMEDIATE STATES, LYASE 
5dso:A   (ALA115) to   (LEU212)  STRUCTURE OF CO2 BOUND APO-FORM OF HUMAN CARBONIC ANHYDRASE II WITH 0 SEC (NO) WARMING  |   CARBONIC ANHYDRASE II, CO2 RELEASE, INTERMEDIATE STATES, LYASE 
5dsp:A   (ALA115) to   (LEU212)  STRUCTURE OF CO2 RELEASED APO-FORM OF HUMAN CARBONIC ANHYDRASE II WITH 40 SEC WARMING  |   CARBONIC ANHYDRASE II, CO2 RELEASE, INTERMEDIATE STATES, LYASE 
5dsq:A   (ALA115) to   (LEU212)  STRUCTURE OF CO2 RELEASED APO-FORM OF HUMAN CARBONIC ANHYDRASE II WITH 3 MIN WARMING  |   CARBONIC ANHYDRASE II, CO2 RELEASE, INTERMEDIATE STATES, LYASE 
5dsr:A   (ALA115) to   (LEU212)  STRUCTURE OF CO2 RELEASED APO-FORM OF HUMAN CARBONIC ANHYDRASE II WITH 10 MIN WARMING  |   CARBONIC ANHYDRASE II, CO2 RELEASE, INTERMEDIATE STATES, LYASE 
1zfk:A  (ALA1115) to  (LEU1212)  CARBONIC ANHYDRASE II IN COMPLEX WITH N-4-SULFONAMIDPHENYL-N'-4- METHYLBENZOSULFONYLUREASE AS SULFONAMIDE INHIBITOR  |   10 STRANDED, TWISTED BETA-SHEETS, LYASE 
1zfq:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH ETHOXZOLAMIDPHENOLE AS SULFONAMIDE INHIBITOR  |   10 STRANDED, TWISTED BETA-SHEETS, LYASE 
1zge:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH P-SULFONAMIDO-O,O'- DICHLOROANILINE AS SULFONAMIDE INHIBITOR  |   10 STRANDED, TWISTED BETA-SHEETS, LYASE 
1zgf:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH TRICHLOROMETHIAZIDE AS SULFONAMIDE INHIBITOR  |   10 STRANDED, TWISTED BETA-SHEETS, LYASE 
1zh9:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH N-4-METHYL-1- PIPERAZINYL-N'-(P-SULFONAMIDE)PHENYLTHIOUREA AS SULFONAMIDE INHIBITOR  |   10 STRANDED, TWISTED BETA-SHEETS, LYASE 
4pyx:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4pyy:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE,METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4pzh:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 2,3,5,6- TETRAFLUORO-4[(2-HYDROXYETHYL)SULFONYL]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE,METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4q06:A   (ALA115) to   (LEU211)  CRYSTAL STRUCTURE OF CHIMERIC CARBONIC ANHYDRASE IX WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE,METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4q09:A   (ALA115) to   (LEU211)  CRYSTAL STRUCTURE OF CHIMERIC CARBONIC ANHYDRASE XII WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE,METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4q49:A   (ALA115) to   (LEU212)  ROOM TEMPERATURE NEUTRON CRYSTAL STRUCTURE OF APO HUMAN CARBONIC ANHYDRASE AT PH 7.5  |   MIXED ALPHA BETA, PROTON TRANSFER, CYTOSOLIC, LYASE 
1zsa:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II MUTANT E117Q, APO FORM  |   LYASE, OXO-ACID, ACETYLATION, ZINC, POLYMORPHISM, LYASE (OXO-ACID) 
1zsb:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II MUTANT E117Q, TRANSITION STATE ANALOGUE ACETAZOLAMIDE  |   LYASE, OXO-ACID, ACETYLATION, ZINC, POLYMORPHISM, LYASE (OXO-ACID) 
1zsc:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II MUTANT E117Q, HOLO FORM  |   LYASE, OXO-ACID, ACETYLATION, ZINC, POLYMORPHISM, LYASE (OXO-ACID) 
5e28:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH THE 4-(4-AMINOPHENYL)BENZENESULFONAMIDE INHIBITOR  |   LYASE 
5e2k:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH THE 4-(3-AMINOPHENYL)BENZENESULFONAMIDE INHIBITOR  |   LYASE 
5e2m:A   (SER115) to   (CYS212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME I WITH 3- (CYCLOOCTYLAMINO)-2,5,6-TRIFLUORO-4-[(2-HYDROXYETHYL) SULFONYL]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, LYASE 
5e2m:B   (SER115) to   (CYS212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME I WITH 3- (CYCLOOCTYLAMINO)-2,5,6-TRIFLUORO-4-[(2-HYDROXYETHYL) SULFONYL]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, LYASE 
5e2n:A   (ALA117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH 3- (CYCLOOCTYLAMINO)-2,5,6-TRIFLUORO-4-[(2-HYDROXYETHYL) SULFONYL]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, LYASE 
5e2n:B   (ALA117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH 3- (CYCLOOCTYLAMINO)-2,5,6-TRIFLUORO-4-[(2-HYDROXYETHYL) SULFONYL]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, LYASE 
5e2r:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A 1,1'-BIPHENYL-4-SULFONAMIDE INHIBITOR  |   1'-BIPHENYL-4-SULFONAMIDE, LYASE, COMPLEX, INHIBITOR 
5e2s:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH THE 4-(2-ISO-PROPYLPHENYL)BENZENESULFONAMIDE INHIBITOR  |   LYASE 
4q6d:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-[(Z)- AZEPAN-1-YLDIAZENYL]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE,METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4q6e:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-{[3- (3,5-DIMETHYL-1H-PYRAZOL-1-YL)-3-OXOPROPYL]AMINO}BENZENE-1- SULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE,METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
5e5r:C   (PRO171) to   (PHE270)  CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBONIC ANHYDRASE-LIKE DOMAIN OF PTPRG AND IMMUNOGLOBULIN DOMAINS 2-3 OF CNTN3  |   NEURAL CELL ADHESION MOLECULE, RECEPTOR-TYPE PROTEIN TYROSINE PHOSPHATASE, IMMUNOGLOBULIN DOMAINS, CARBONIC ANHYDRASE-LIKE DOMAIN, HYDROLASE-CELL ADHESION COMPLEX 
5e5u:A   (PRO171) to   (PHE270)  CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBONIC ANHYDRASE-LIKE DOMAIN OF PTPRG AND IMMUNOGLOBULIN DOMAINS 2-3 OF CNTN6  |   NEURAL CELL ADHESION MOLECULE, RECEPTOR-TYPE PROTEIN TYROSINE PHOSPHATASE, IMMUNOGLOBULIN DOMAINS, CARBONIC ANHYDRASE-LIKE DOMAIN, CELL ADHESION-HYDROLASE COMPLEX 
5e5u:C   (PRO171) to   (PHE270)  CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBONIC ANHYDRASE-LIKE DOMAIN OF PTPRG AND IMMUNOGLOBULIN DOMAINS 2-3 OF CNTN6  |   NEURAL CELL ADHESION MOLECULE, RECEPTOR-TYPE PROTEIN TYROSINE PHOSPHATASE, IMMUNOGLOBULIN DOMAINS, CARBONIC ANHYDRASE-LIKE DOMAIN, CELL ADHESION-HYDROLASE COMPLEX 
4q7p:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF 1-HYDROXY-3-METHYLPYRIDINE-2(1H)-THIONE BOUND TO HCAII  |   LYASE 
4q7s:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF 1-HYDROXY-4-METHYLPYRIDINE-2(1H)-THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II  |   LYASE 
4q7v:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF 1-HYDROXY-5-METHYLPYRIDINE-2(1H)-THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II  |   LYASE 
4q7w:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF 1-HYDROXY-6-METHYLPYRIDINE-2(1H)-THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II  |   LYASE 
4q81:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF 1-HYDROXY-4,6-DIMETHYLPYRIDINE-2(1H)-THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II  |   LYASE 
4q83:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF 1-HYDROXY-3-(TRIFLUOROMETHYL)PYRIDINE-2(1H)- THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II  |   LYASE 
4q87:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF 1-HYDROXY-4-(TRIFLUOROMETHYL)PYRIDINE-2(1H)- THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II  |   LYASE 
3lxe:A   (SER115) to   (CYS212)  HUMAN CARBONIC ANHYDRASE I IN COMPLEX WITH TOPIRAMATE  |   CARBONIC ANHYDRASE 1, TOPIRAMATE, ENZYME-INHIBITOR COMPLEX, LYASE 
3lxe:B   (SER115) to   (CYS212)  HUMAN CARBONIC ANHYDRASE I IN COMPLEX WITH TOPIRAMATE  |   CARBONIC ANHYDRASE 1, TOPIRAMATE, ENZYME-INHIBITOR COMPLEX, LYASE 
4q8x:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF 1-HYDROXY-5-(TRIFLUOROMETHYL)PYRIDINE-2(1H)- THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II  |   LYASE 
4q8y:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF 2-HYDROXYISOQUINOLINE-1(2H)-THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II  |   LYASE 
4q8z:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF 1-HYDROXY-4-METHYLPYRIDIN-2(1H)-ONE BOUND TO HUMAN CARBONIC ANHYDRASE II  |   LYASE 
4q90:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF 4-METHYLPYRIDINE-2(1H)-THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II  |   LYASE 
4q99:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF 2-MERCAPTO-4-METHYLPHENOL BOUND TO HUMAN CARBONIC ANHYDRASE II  |   LYASE 
3m04:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH NOVEL SULFONAMIDE INHIBITOR  |   10 STRANDED TWISTED BETA-SHEETS, LYASE, DISEASE MUTATION, METAL- BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4q9y:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF 3-METHYLTHIOPHENOL BOUND TO HUMAN CARBONIC ANHYDRASE II  |   LYASE 
3m14:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH NOVEL SULFONAMIDE INHIBITOR  |   10 STRANDED TWISTED BETA-SHEETS, LYASE, DISEASE MUTATION, METAL- BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3m1j:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF A NAMI A-CARBONIC ANHYDRASE II ADDUCT DISCLOSES THE MODE OF ACTION OF THIS NOVEL ANTICANCER METALLODRUG  |   RUTHENIUM COMPLEXES, NAMI-A, ANTIMETASTATIC AGENTS, CARBONIC ANHYDRASE, LYASE 
3m1k:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE IN COMPLEX WITH FRAGMENT  |   10 STRANDED TWISTED BETA-SHEETS, LYASE, DISEASE MUTATION, METAL- BINDING 
3m1q:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II MUTANT W5C-H64C WITH OPENED DISULFIDE BOND  |   10 STRANDED TWISTED BETA-SHEETS, LYASE, DISEASE MUTATION, METAL- BINDING 
3m1w:A   (ALA115) to   (LEU212)  CARBONIC ANHYRDASE II MUTANT W5CH64C WITH CLOSED DISULFIDE BOND IN COMPLEX WITH SULFATE  |   10 STRANDED TWISTED BETA-SHEETS, LYASE, DISEASE MUTATION, METAL- BINDING 
3m2n:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-{2-[N- (6-CHLORO-5-NITROPYRIMIDIN-4-YL)AMINO]ETHYL}BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, SULFONAMIDE, LYASE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3m2x:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH NOVEL SULFONAMIDE INHIBITOR  |   10 STRANDED TWISTED BETA-SHEETS, LYASE, DISEASE MUTATION, METAL- BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3m2y:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH NOVEL SULFONAMIDE INHIBITOR  |   10 STRANDED TWISTED BETA-SHEETS, LYASE, DISEASE MUTATION, METAL- BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3m2z:A   (ALA115) to   (LEU212)  FRAGMENT TETHERED TO CARBONIC ANHYDRASE II H64C MUTANT  |   10 STRANDED TWISTED BETA-SHEETS, LYASE, DISEASE MUTATION, METAL- BINDING 
4qef:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II V207I - CYANATE INHIBITOR COMPLEX  |   LYASE, PROTON TRANSFER, LYASE-LYASE INHIBITOR COMPLEX 
3m3x:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-{2-[N- (6-METHOXY-5-NITROPYRIMIDIN-4-YL)AMINO]ETHYL}BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, SULFONAMIDE, METAL-BINDING, LYASE- LYASE INHIBITOR COMPLEX 
3m40:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-[N-(6- CHLORO-5-NITROPYRIMIDIN-4-YL)AMINO]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, SULFONAMIDE, METAL-BINDING, LYASE- LYASE INHIBITOR COMPLEX 
3m5e:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-{[N- (6-CHLORO-5-FORMYL-2-METHYLTHIOPYRIMIDIN-4-YL) AMINO]METHYL}BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, SULFONAMIDE, METAL-BINDING, LYASE- LYASE INHIBITOR COMPLEX 
3m5s:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II MUTANT H64C IN COMPLEX WITH CARBONATE  |   STRANDED TWISTED BETA-SHEETS, LYASE, DISEASE MUTATION, METAL-BINDING 
3m5t:A   (ALA115) to   (LEU212)  FRAGMENT TETHERED TO CARBONIC ANHYDRASE II H64C MUTANT  |   STRANDED TWISTED BETA-SHEETS, LYASE, DISEASE MUTATION, METAL-BINDING 
3m67:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 2- CHLORO-5-[(6,7-DIHYDRO-1H-[1,4]DIOXINO[2,3-F]BENZIMIDAZOL-2- YLSULFANYL)ACETYL]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3m96:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 5-{[(5- BROMO-1H-BENZIMIDAZOL-2-YL)SULFANYL]ACETYL}-2- CHLOROBENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, LYASE 
3m98:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 5-(1H- BENZIMIDAZOL-1-YLACETYL)-2-CHLOROBENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, LYASE 
3b4f:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE INHIBITORS. INTERACTION OF 2- (HYDRAZINOCARBONYL)-3-PHENYL-1H-INDOLE-5-SULFONAMIDE WITH TWELVE MAMMALIAN ISOFORMS: KINETIC AND X-RAY CRYSTALLOGRAPHIC STUDIES  |   CARBONIC ANHYDRASE, INHIBITORS, CRYSTAL STRUCTURE, SULFONAMIDE, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL-BINDING, POLYMORPHISM, ZINC, LYASE(OXO-ACID) 
5eh5:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH LIGAND  |   HUMAN CARBONIC ANHYDRASE, LIGAND, LYASE 
5eh7:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH LIGAND  |   HUMAN CARBONIC ANHYDRASE, LYASE 
5eh8:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH LIGAND  |   HUMAN CARBONIC ANHYDRASE, LYASE 
5ehe:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 3- (BENZYLAMINO)-2,5,6-TRIFLUORO-4-[(2-HYDROXYETHYL) SULFONYL]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX, LYASE 
5ehv:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH LIGAND  |   HUMAN CARBONIC ANHYDRASE II, TRANSFERASE 
2abe:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE ACTIVATORS: X-RAY CRYSTAL STRUCTURE OF THE ADDUCT OF HUMAN ISOZYME II WITH L-HISTIDINE AS A PLATFORM FOR THE DESIGN OF STRONGER ACTIVATORS  |   PROTEIN-ACTIVATOR COMPLEX, LYASE 
5ehw:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH LIGAND  |   HUMAN CARBONIC ANHYDRASE II, TRANSFERASE 
4qiz:A   (ALA117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4qiz:B   (ALA117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
5eij:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH SULFONAMIDE INHIBITOR  |   SULFONAMIDE, INHIBITOR, LYASE-LYASE INHIBITOR COMPLEX 
4qjm:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE,METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4qjp:B   (ALA117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE,METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4qjp:A   (ALA117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE,METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4qjx:A   (ALA117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE,METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4qk1:A   (ALA115) to   (LEU212)  STRUCTURAL AND CATALYTIC EFFECTS OF PROLINE SUBSTITUTION AND SURFACE LOOP DELETION IN THE EXTENDED ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II - K170P  |   LYASE 
4qk2:A   (ALA115) to   (LEU212)  STRUCTURAL AND CATALYTIC EFFECTS OF PROLINE SUBSTITUTION AND SURFACE LOOP DELETION IN THE EXTENDED ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II - E234P  |   LYASE 
4qk3:A   (ALA115) to   (LEU212)  STRUCTURAL AND CATALYTIC EFFECTS OF PROLINE SUBSTITUTION AND SURFACE LOOP DELETION IN THE EXTENDED ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II - [DELTA]230-240  |   LYASE 
4bcw:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE IX MIMIC IN COMPLEX WITH (E)-2-(5-BROMO- 2-HYDROXYPHENYL)ETHENESULFONIC ACID  |   LYASE, SULFOCOUMARIN 
5ekh:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH A TWO-FACED GUEST  |   LYASE-LYASE INHIBITOR COMPLEX 
5ekj:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH A TWO-FACED GUEST  |   LYASE-LYASE INHIBITOR COMPLEX 
5ekm:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH A TWO-FACED GUEST  |   LYASE-LYASE INHIBITOR COMPLEX 
3mhi:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-{[(5- NITRO-6-OXO-1,6-DIHYDRO-4-PYRIMIDINYL)AMINO]METHYL}BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, SULFONAMIDE, LYASE-LYASE INHIBITOR COMPLEX 
3mhm:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-{[N- (6-BENZYLAMINO-5-NITROPYRIMIDIN-4-YL)AMINO]METHYL}BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, SULFONAMIDE, LYASE-LYASE INHIBITOR COMPLEX 
3mho:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-[N-(6- CHLORO-5-FORMYL-2-METHYLTHIOPYRIMIDIN-4-YL)AMINO]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, SULFONAMIDE, LYASE-LYASE INHIBITOR COMPLEX 
5eoi:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF COPPER BOUND HUMAN CARBONIC ANHYDRASE II  |   LYASE 
4bf6:A   (ALA115) to   (LEU212)  THREE DIMENSIONAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 5-(1-(3-CYANOPHENYL)-1H-1,2,3-TRIAZOL-4-YL) THIOPHENE-2-SULFONAMIDE  |   LYASE 
4qsb:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 3-{[(4- METHYL-6-OXO-1,6-DIHYDROPYRIMIDIN-2-YL)THIO]ACETYL}BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3mmf:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A 1, 3,5-TRIAZINE-SUBSTITUTED BENZENESULFONAMIDE INHIBITOR  |   ZINC METALLOENZYME, INHIBITOR, SULFONAMIDE, METAL-BINDING, TRIAZINE, LYASE, LYASE-LYASE INHIBITOR COMPLEX 
4qsi:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 5-{[(4- TERT-BUTHYL-6-OXO-1,6-DIHYDROPYRIMIDIN-2-YL)THIO]ACETYL}-2- CHLOROBENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4qsj:B   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH 2- CHLORO-4-{[(4-METHYL-6-OXO-1,6-DIHYDROPYRIMIDIN-2-YL) THIO]ACETYL}BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4qsj:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME XIII WITH 2- CHLORO-4-{[(4-METHYL-6-OXO-1,6-DIHYDROPYRIMIDIN-2-YL) THIO]ACETYL}BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3mna:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A 1,3,5-TRIAZINE-SUBSTITUTED BENZENESULFONAMIDE INHIBITOR  |   ZINC METALLOENZYME, INHIBITOR, SULFONAMIDE, LYASE, TRIAZINE, LYASE- LYASE INHIBITOR COMPLEX 
3mni:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II MUTANT K170D  |   PROTON TRANSFER, METALLOENZYME, PROTON TRANSPORT 
3mnj:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II MUTANT K170E  |   PROTON TRANSFER, METALLOENZYME, PROTON TRANSPORT 
3mnk:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II MUTANT K170H  |   PROTON TRANSFER, METALLOENZYME, PROTON TRANSPORT 
4qtl:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3bl0:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE INHIBITORS. INTERACTION OF 2-N,N- DIMETHYLAMINO-1,3,4-THIADIAZOLE-5-METHANESULFONAMIDE WITH TWELVE MAMMALIAN ISOFORMS: KINETIC AND X-RAY CRYSTALLOGRAPHIC STUDIES  |   CARBONIC ANHYDRASE, INHIBITORS, CRYSTAL STRUCTURE, SULFONAMIDE, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL-BINDING, POLYMORPHISM, ZINC, LYASE(OXO-ACID) 
5ezt:X   (ALA114) to   (LEU210)  PERACETYLATED BOVINE CARBONIC ANHYDRASE II  |   CARBONIC ANHYDRASE, PERACETYLATED, TRANSFERASE 
3mwo:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN A DOUBLED MONOCLINIC CELL: A RE- DETERMINATION  |   DOUBLED UNIT CELL, LYASE, PSEUDOSYMMETRY, TRANSLATIONAL NCS 
3mwo:B   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN A DOUBLED MONOCLINIC CELL: A RE- DETERMINATION  |   DOUBLED UNIT CELL, LYASE, PSEUDOSYMMETRY, TRANSLATIONAL NCS 
3myq:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 2- CHLORO-5-[(1H-IMIDAZO[4,5-C]QUINOLIN-2-YLSULFANYL) ACETYL]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, LYASE 
3mzc:A   (ALA115) to   (LEU212)  HUMAN CARBONIC AHYDRASE II IN COMPLEX WITH A BENZENESULFONAMIDE INHIBITOR  |   LYASE, BENZENESULFONAMIDE INHIBITOR, ZINC METALLOENZYME, ZINC COORDINATION, LYASE-LYASE INHIBITOR COMPLEX 
3n0n:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A BENZENESULFONAMIDE INHIBITOR  |   ZINC METALLOENZYME LYASE, BENZENESULFONAMIDE INHIBITOR, ZINC LIGANDS, , LYASE, LYASE-LYASE INHIBITOR COMPLEX 
3n2p:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A BENZENESULFONAMIDE INHIBITOR  |   LYASE, ZINC METALLOENZYME, ZINC LIGANDS, BENZENESULFONAMIDE, INHIBITOR., LYASE-LYASE INHIBITOR COMPLEX 
5fdc:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH THE ANTICONVULSANT SULFAMIDE JNJ-26990990 AND ITS S,S-DIOXIDE ANALOG.  |   SULFAMIDE INHIBITOR, PROTEIN-INHIBITOR COMPLEX, LYASE 
4r5a:A   (ALA115) to   (LEU212)  A CARBONIC ANHYDRASE IX MIMIC IN COMPLEX WITH A CARBOHYDRATE-BASED SULFAMATE  |   CARBONIC ANHYDRASE IX MIMIC, LYASE 
4r5b:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A CARBOHYDRATE-BASED SULFAMATE  |   CYTOSOL, LYASE 
3c7p:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH STX237  |   PROTEIN-INHIBITOR COMPLEX, DISEASE MUTATION, LYASE, METAL-BINDING 
3ca2:A   (ALA115) to   (LEU212)  CRYSTALLOGRAPHIC STUDIES OF INHIBITOR BINDING SITES IN HUMAN CARBONIC ANHYDRASE II. A PENTACOORDINATED BINDING OF THE SCN-ION TO THE ZINC AT HIGH P*H  |   LYASE(OXO-ACID) 
3caj:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH ETHOXZOLAMIDE  |   PROTEIN-INHIBITOR COMPLEX, DISEASE MUTATION, LYASE, METAL-BINDING 
4rfc:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH TERT-BUTYL 4-(4- SULFAMOYLPHENOXY)BUTYLCARBAMATE  |   SULFONAMIDE, CARBONIC ANHYDRASE, ANTIGLAUCOMA, O-(-AMINOALKYL)- BENZENESULFONAMIDES, LYASE 
4rfd:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 4-(4-SULFAMOYL-PHENOXY)- BUTYLAMMONIUM  |   SULFONAMIDE, CARBONIC ANHYDRASE, ANTIGLAUCOMA, O-(-AMINOALKYL)- BENZENESULFONAMIDESS, LYASE 
5flo:A   (ALA115) to   (LEU212)  NATIVE STATE MASS SPECTROMETRY, SURFACE PLASMON RESONANCE AND X-RAY CRYSTALLOGRAPHY CORRELATE STRONGLY AS A FRAGMENT SCREENING COMBINATION  |   LYASE, CARBONIC ANHYDRASE, METALLOPROTEIN 
5flp:A   (ALA115) to   (LEU212)  NATIVE STATE MASS SPECTROMETRY, SURFACE PLASMON RESONANCE AND X-RAY CRYSTALLOGRAPHY CORRELATE STRONGLY AS A FRAGMENT SCREENING COMBINATION  |   LYASE, CARBONIC ANHYDRASE, METALLOPROTEIN 
5flq:A   (ALA115) to   (LEU212)  NATIVE STATE MASS SPECTROMETRY, SURFACE PLASMON RESONANCE AND X-RAY CRYSTALLOGRAPHY CORRELATE STRONGLY AS A FRAGMENT SCREENING COMBINATION  |   LYASE, FRAGMENTS, CARBONIC ANHYDRASE, METALLOPROTEIN 
4rh2:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 2-(6- HYDROXY-3-OXO-3H-XANTHEN-9-YL)-5-{3-1-(4-SULFAMOYL-PHENYL)-1H-[1,2, 3]TRIAZOL-4-YLMETHYL-THIOUREIDO}-BENZOIC ACID  |   LYASE 
3nj9:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF CARBONIC ANHYDRASE II IN COMPLEX WITH A NIR INHIBITOR  |   CARBONIC ANHYDRASE, NIR MOIETY, INHIBITORS, LYASE-LYASE INHIBITOR COMPLEX 
5fng:A   (ALA115) to   (LEU212)  NATIVE STATE MASS SPECTROMETRY, SURFACE PLASMON RESONANCE AND X-RAY CRYSTALLOGRAPHY CORRELATE STRONGLY AS A FRAGMENT SCREENING COMBINATION  |   LYASE, FRAGMENTS, CARBONIC ANHYDRASE, METALLOPROTEIN 
5fnh:A   (ALA115) to   (LEU212)  NATIVE STATE MASS SPECTROMETRY, SURFACE PLASMON RESONANCE AND X-RAY CRYSTALLOGRAPHY CORRELATE STRONGLY AS A FRAGMENT SCREENING COMBINATION  |   LYASE, FRAGMENTS, CARBONIC ANHYDRASE, METALLOPROTEIN 
5fnj:A   (ALA115) to   (LEU212)  NATIVE STATE MASS SPECTROMETRY, SURFACE PLASMON RESONANCE AND X-RAY CRYSTALLOGRAPHY CORRELATE STRONGLY AS A FRAGMENT SCREENING COMBINATION  |   LYASE, FRAGMENTS, CARBONIC ANHYDRASE, METALLOPROTEIN 
5fnk:A   (ALA115) to   (LEU212)  NATIVE STATE MASS SPECTROMETRY, SURFACE PLASMON RESONANCE AND X-RAY CRYSTALLOGRAPHY CORRELATE STRONGLY AS A FRAGMENT SCREENING COMBINATION  |   LYASE, FRAGMENTS, CARBONIC ANHYDRASE, METALLOPROTEIN 
5fnl:A   (ALA115) to   (LEU212)  NATIVE STATE MASS SPECTROMETRY, SURFACE PLASMON RESONANCE AND X-RAY CRYSTALLOGRAPHY CORRELATE STRONGLY AS A FRAGMENT SCREENING COMBINATION  |   LYASE, FRAGMENTS, CARBONIC ANHYDRASE, METALLOPROTEIN 
5fnm:A   (ALA115) to   (LEU212)  NATIVE STATE MASS SPECTROMETRY, SURFACE PLASMON RESONANCE AND X-RAY CRYSTALLOGRAPHY CORRELATE STRONGLY AS A FRAGMENT SCREENING COMBINATION  |   LYASE, FRAGMENTS, CARBONIC ANHYDRASE, METALLOPROTEIN 
4riu:A   (ALA115) to   (LEU212)  A CARBONIC ANHYDRASE IX MIMIC IN COMPLEX WITH A SACCHARIN-BASED INHIBITOR  |   CARBONIC ANHYDRASE FOLD, REVERSIBLE HYDRATION OF CO2, ACTIVE SITE POINT MUTATIONS, CYTOSOLIC, LYASE-LYASE INHIBITOR COMPLEX 
4riv:A   (ALA115) to   (LEU212)  A CARBONIC ANHYDRASE IX MIMIC IN COMPLEX WITH SACCHARIN  |   CARBONIC ANHYDRASE FOLD, REVERSIBLE HYDRATION OF CO2, ACTIVE SITE POINT MUTATIONS, CYTOSOLIC, LYASE 
4cac:A   (ALA115) to   (LEU212)  REFINED STRUCTURE OF HUMAN CARBONIC ANHYDRASE II AT 2.0 ANGSTROMS RESOLUTION  |   LYASE(OXO-ACID) 
4rn4:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASES II IN COMPLEX WITH A ACETAZOLAMIDE DERIVATIVE COMPRISING ONE HYDROPHOBIC AND ONE HYDROPHILIC TAIL MOIETY  |   CARBONIC ANHYDRASE, ACETAZOLAMIDE, LYASE-LYASE INHIBITOR COMPLEX 
4rux:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 4- (ALLYLOXY)BENZENESULFONAMIDE  |   METALLOENZYME, ANALGESIC, LYASE 
4ruy:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 4- PROPOXYBENZENESULFONAMIDE  |   METALLOENZYME, ANALGESIC, LYASE 
4ruz:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 4- ETHOXYBENZENESULFONAMIDE  |   METALLOENZYME, ANALGESIC, LYASE 
4cnv:A   (ALA115) to   (LEU211)  SURFACE RESIDUE ENGINEERING OF BOVINE CARBONIC ANHYDRASE TO AN EXTREME HALOPHILIC ENZYME FOR POTENTIAL APPLICATION IN POSTCOMBUSTION CO2 CAPTURE  |   LYASE, PROTEIN ENGINEERING 
4cnw:A   (ALA115) to   (LEU211)  SURFACE RESIDUE ENGINEERING OF BOVINE CARBONIC ANHYDRASE TO AN EXTREME HALOPHILIC ENZYME FOR POTENTIAL APPLICATION IN POSTCOMBUSTION CO2 CAPTURE  |   LYASE, PROTEIN ENGINEERING, CO2 CAPTURE 
4cnw:B   (ALA115) to   (LEU211)  SURFACE RESIDUE ENGINEERING OF BOVINE CARBONIC ANHYDRASE TO AN EXTREME HALOPHILIC ENZYME FOR POTENTIAL APPLICATION IN POSTCOMBUSTION CO2 CAPTURE  |   LYASE, PROTEIN ENGINEERING, CO2 CAPTURE 
4cnx:A   (ALA115) to   (LEU211)  SURFACE RESIDUE ENGINEERING OF BOVINE CARBONIC ANHYDRASE TO AN EXTREME HALOPHILIC ENZYME FOR POTENTIAL APPLICATION IN POSTCOMBUSTION CO2 CAPTURE  |   LYASE, PROTEIN ENGINEERING, CO2 CAPTURE 
5g01:A   (ALA115) to   (LEU212)  AN UNUSUAL NATURAL PRODUCT PRIMARY SULFONAMIDE: SYNTHESIS, CARBONIC ANHYDRASE INHIBITION AND PROTEIN X-RAY STRUCTURE OF PSAMMAPLIN C  |   LYASE, NATURAL PRODUCT INHIBITOR, ENGINEERED PROTEINS, CARBONIC ANHYDRASE 
5g03:A   (ALA115) to   (LEU212)  AN UNUSUAL NATURAL PRODUCT PRIMARY SULFONAMIDE: SYNTHESIS, CARBONIC ANHYDRASE INHIBITION AND PROTEIN X-RAY STRUCTURE OF PSAMMAPLIN C  |   LYASE, NATURAL PRODUCT INHIBITOR, PROTEIN ENGINEERING, CARBONIC ANHYDRASE 
3d0n:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE XIII  |   CARBONIC ANHYDRASE, LYASE, METAL-BINDING, METAL BINDING PROTEIN 
4cq0:A   (ALA115) to   (LEU212)  CYCLIC SECONDARY SULFONAMIDES: UNUSUALLY GOOD INHIBITORS OF CANCER-RELATED CARBONIC ANHYDRASE ENZYMES  |   LYASE, SACCHARIN, CLICK CHEMISTRY, DRUG DESIGN 
5g0c:A   (ALA115) to   (LEU212)  AN UNUSUAL NATURAL PRODUCT PRIMARY SULFONAMIDE: SYNTHESIS, CARBONIC ANHYDRASE INHIBITION AND PROTEIN X-RAY STRUCTURE OF PSAMMAPLIN C  |   LYASE, PROTEIN ENGINEERING, NATURAL PRODUCT INHIBITOR, CARBONIC ANHYDRASE 
3d8w:A   (ALA115) to   (LEU212)  USE OF A CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI- CANCER PROPERTIES  |   CARBONIC ANHYDRASE II, ANTI-CANCER, BENZOLAMIDE, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL- BINDING, POLYMORPHISM, ZINC 
3d92:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II BOUND WITH SUBSTRATE CARBON DIOXIDE  |   ZINC METALLOENZYME, SUBSTRATE-BOUND, DISEASE MUTATION, LYASE, METAL- BINDING 
3d93:A   (ALA115) to   (LEU212)  APO HUMAN CARBONIC ANHYDRASE II BOUND WITH SUBSTRATE CARBON DIOXIDE  |   ZINC METALLOENZYME, SUBSTRATE-BOUND, DISEASE MUTATION, LYASE, METAL- BINDING 
3d9z:A   (ALA115) to   (LEU212)  USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES  |   CARBONIC ANHYDRASE II COMPLEX, CAIX MIMIC INHIBITORS, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL- BINDING, POLYMORPHISM, ZINC 
3da2:B   (ALA116) to   (LEU213)  X-RAY STRUCTURE OF HUMAN CARBONIC ANHYDRASE 13 IN COMPLEX WITH INHIBITOR  |   CARBONIC ANHYDRASE, SULFONAMIDE, SGC, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, LYASE, METAL-BINDING 
3daz:A   (ALA115) to   (LEU212)  USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES  |   CARBONIC ANHYDRASE II COMPLEX, CAIX MIMIC INHIBITORS, DISEASE MUTATION, LYASE, METAL-BINDING 
3dbu:A   (ALA115) to   (LEU212)  USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES  |   CARBONIC ANHYDRASE II COMPLEX, CAIX MIMIC INHIBITORS, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL- BINDING, POLYMORPHISM, ZINC 
3dc9:A   (ALA115) to   (LEU212)  USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES  |   CARBONIC ANHYDRASE II COMPLEX, CAIX MIMIC INHIBITORS, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL- BINDING, POLYMORPHISM, ZINC 
3dcc:A   (ALA115) to   (LEU212)  USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES  |   CARBONIC ANHYDRASE II COMPLEX, CAIX MIMIC INHIBITORS, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL- BINDING, POLYMORPHISM, ZINC 
3dcs:A   (ALA115) to   (LEU212)  USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES  |   CARBONIC ANHYDRASE II COMPLEX, CAIX MIMIC INHIBITORS, DISEASE MUTATION, LYASE, METAL-BINDING 
3dcw:A   (ALA115) to   (LEU212)  USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES  |   CARBONIC ANHYDRASE II COMPLEX, CAIX MIMIC INHIBITORS, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL- BINDING, POLYMORPHISM, ZINC 
3oik:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II MUTANT A65S, N67Q (CA IX MIMIC) BOUND BY 2-ETHYLESTRADIOL 3,17-O,O-BIS-SULFAMATE  |   2-ETHYLESTRONE, ESTRADIOL, SULFAMATE, MIXED ALPHA-BETA, CARBON DIOXIDE/BICARBONATE CONVERSION, LYASE 
3oil:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II MUTANT A65S, N67Q (CA IX MIMIC) BOUND BY 2-ETHYLESTRADIOL 3-O-SULFAMATE  |   2-ETHYLESTRONE, ESTRADIOL, SULFAMATE, MIXED ALPHA-BETA, CARBON DIOXIDE/BICARBONATE CONVERSION, LYASE 
3oim:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II BOUND BY 2-ETHYLESTRADIOL 3-O-SULFAMATE  |   2-ETHYLESTRONE, ESTRADIOL, SULFAMATE, MIXED ALPHA-BETA, CARBON DIOXIDE/BICARBONATE CONVERSION, LYASE 
3oku:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 2-ETHYLESTRONE-3-O- SULFAMATE  |   MIXED ALPHA/BETA FOLD, REVERSIBLE HYDRATION OF CARBON DIOXIDE TO BICARBONATE, LYASE 
3okv:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II A65S, N67Q (CA IX MIMIC) BOUND WITH 2- ETHYLESTRONE 3-O-SULFAMATE  |   MIXES ALPHA/BETA FOLD, REVERSIBLE HYDRATION OF CARBON DIOXIDE TO BICARBONATE, LYASE 
3dvd:A   (ALA115) to   (LEU212)  X-RAY CRYSTAL STRUCTURE OF MUTANT N62D OF HUMAN CARBONIC ANHYDRASE II  |   HUMAN CARBONIC ANHYDRASE II, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL-BINDING, POLYMORPHISM, ZINC 
3oyq:A   (ALA115) to   (LEU212)  STRUCTURE OF HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH 5,6-DIHYDRO- BENZO[H]CINNOLIN-3-YLAMINE  |   BENZENE SULPHONAMIDE INHIBITOR, DRUG INTERACTIONS, LYASE-LYASE INHIBITOR COMPLEX 
3oys:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH 2-{[4-AMINO-3-(3- HYDROXYPROP-1-YN-1-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]METHYL}-5- METHYL-3-(2-METHYLPHENYL)QUINAZOLIN-4(3H)-ONE  |   BENZENE SULPHONAMIDE INHIBITOR, DRUG INTERACTIONS, LYASE-LYASE INHIBITOR COMPLEX 
3p3j:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH P-(5-RUTHENOCENYL-1H-1,2, 3-TRIAZOL-1-YL)BENZENESULFONAMIDE  |   CARBONIC ANHYDRASE ALPHA, LYASE, CYTOSOLIC 
3p44:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH P-(4-RUTHENOCENYL-1H-1,2, 3-TRIAZOL-1-YL)BENZENESULFONAMIDE  |   CARBONIC ANHYDRASE ALPHA, LYASE, CYTOSOLIC 
3p4v:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH (+)-XYLARIAMIDE A  |   CARBONIC ANHYDRASE, ALPHA TYPE, LYASE-LYASE INHIBITOR COMPLEX 
3p55:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH P-(4-FERROCENYL-1H-1,2,3- TRIAZOL-1-YL)BENZENESULFONAMIDE  |   CARBONIC ANHYDRASE ALPHA, LYASE, CYTOSOLIC 
3p58:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE IN COMPLEX WITH BENZYL (METHYL) CARBAMODITHOIC ACID  |   CARBOTHIOATES, HCAII INHIBITORS, LYASE-INHIBITOR COMPLEX 
3p5a:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE COMPLEXED WITH SODIUM MORPHOLINOCARBODITHIOATE  |   CARBOTHIOATES, HCAII INHIBITORS, LYASE-INHIBITOR COMPLEX 
3p5l:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE COMPLEXED WITH SODIUM 4-CYANO-4- PHENYLPIPERIDINE-1-CARBODITHIOATE  |   CARBOTHIOATES, HCAII INHIBITORS, LYASE-INHIBITOR COMPLEX 
4dz7:A   (ALA115) to   (LEU212)  HCA II IN COMPLEX WITH NOVEL SULFONAMIDE INHIBITORS SET D  |   MIXED A/B GLOBULAR PROTEIN, INTERCONVERSION OF CO2 AND BICARBONATE, LYASE-LYASE INHIBITOR COMPLEX 
4dz9:A   (ALA115) to   (LEU212)  HCA II IN COMPLEX WITH NOVEL SULFONAMIDE INHIBITORS SET D  |   MIXED A/B GLOBULAR PROTEIN, INTERCONVERSION OF CO2 AND BICARBONATE, LYASE-LYASE INHIBITOR COMPLEX 
4e3d:A   (ALA115) to   (LEU212)  NUCLEOPHILE RECOGNITION AS AN ALTERNATIVE INHIBITION MODE FOR BENZOIC ACID BASED CARBONIC ANHYDRASE INHIBITORS  |   CARBONATE DEHYDRATASE, LYASE-LYASE INHIBITOR COMPLEX 
4e3f:A   (ALA115) to   (LEU212)  NUCLEOPHILE RECOGNITION AS AN ALTERNATIVE INHIBITION MODE FOR BENZOIC ACID BASED CARBONIC ANHYDRASE INHIBITORS  |   CARBONATE DEHYDRATASE, INHIBITOR BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4e3g:A   (ALA115) to   (LEU212)  NUCLEOPHILE RECOGNITION AS AN ALTERNATIVE INHIBITION MODE FOR BENZOIC ACID BASED CARBONIC ANHYDRASE INHIBITORS  |   CARBONATE DEHYDRATASE, INHIBITOR, LYASE-LYASE INHIBITOR COMPLEX 
4e3h:A   (ALA115) to   (LEU212)  NUCLEOPHILE RECOGNITION AS AN ALTERNATIVE INHIBITION MODE FOR BENZOIC ACID BASED CARBONIC ANHYDRASE INHIBITORS  |   CARBONATE DEHYDRATASE, INHIBITOR, LYASE-LYASE INHIBITOR COMPLEX 
4e49:A   (ALA115) to   (LEU212)  NUCLEOPHILE RECOGNITION AS AN ALTERNATIVE INHIBITION MODE FOR BENZOIC ACID BASED CARBONIC ANHYDRASE INHIBITORS  |   CARBONATE DEHYDRATASE, INHIBITOR, LYASE-LYASE INHIBITOR COMPLEX 
4e4a:A   (ALA115) to   (LEU212)  NUCLEOPHILE RECOGNITION AS AN ALTERNATIVE INHIBITION MODE FOR BENZOIC ACID BASED CARBONIC ANHYDRASE INHIBITORS  |   CARBONATE DEHYDRATASE, INHIBITOR, LYASE-LYASE INHIBITOR COMPLEX 
4e5q:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH CYANATE  |   MIXED ALPHA BETA PROTEIN, ENZYME PROTON TRANSFER, LYASE 
3pyk:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II AS HOST FOR PIANOSTOOL COMPLEXES BEARING A SULFONAMIDE ANCHOR  |   10 STRANDED, TWISTED BETA-SHEETS, CARBONATE DEHYDRATASE ACTIVITY, PROTEIN BINDING, ZINC ION BINDING, LYASE ACTIVITY, METAL ION BINDING, CO2, BICARBONATE, SULFONAMIDES, METAL IONS, LYASE-LYASE INHIBITOR COMPLEX 
4etq:X    (SER88) to   (THR187)  VACCINIA VIRUS D8L IMV ENVELOPE PROTEIN IN COMPLEX WITH FAB OF MURINE IGG2A LA5  |   VARIABLE DOMAIN, CONSTANT DOMAIN, IGG2A, IGG DOMAIN, CDR, HYPERVARIABLE REGION, NEUTRALIZING ANTIBODY, BETA SHEET, CARBONIC ANHYDRASE FOLD, LOOSE KNOT, CHONDROITIN-SULFATE BINDING SITE, DELTA 262, IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX 
4etq:C    (SER88) to   (THR187)  VACCINIA VIRUS D8L IMV ENVELOPE PROTEIN IN COMPLEX WITH FAB OF MURINE IGG2A LA5  |   VARIABLE DOMAIN, CONSTANT DOMAIN, IGG2A, IGG DOMAIN, CDR, HYPERVARIABLE REGION, NEUTRALIZING ANTIBODY, BETA SHEET, CARBONIC ANHYDRASE FOLD, LOOSE KNOT, CHONDROITIN-SULFATE BINDING SITE, DELTA 262, IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX 
3qyk:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH TRIPLE RING BENZENE SULFONAMIDE INHIBITOR  |   HYDRATION OF CO2, CO2, LYASE-LYASE INHIBITOR COMPLEX 
4fik:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II H64A COMPLEXED WITH THIOXOLONE HYDROLYSIS PRODUCTS  |   CARBONIC ANHYDRASE II, HUMAN CARBONIC ANHYDRASE II, HCA II, HCA2, CA II, CA2, CARBONATE DEHYDRATASE II, CARBONIC ANHYDRASE C, THIOXOLONE, 4-MERCAPTOBENZENE-1,3-DIOL, 4-(2,4-DIHYDROXYPHENYL) DISULFANYLBENZENE-1,3-DIOL, DISEASE MUTATION, LYASE, METAL-BINDING 
3r16:A   (ALA115) to   (LEU212)  HUMAN CAII BOUND TO N-(4-SULFAMOYLPHENYL)-2-(THIOPHEN-2-YL) ACETAMIDE  |   REVERSIBLE HYDRATION OF CARBONDIOXIDE, LYASE 
3r17:B   (ALA115) to   (LEU212)  HCARBONIC ANHYDRASE II BOUND TO N-(2-FLUORO.4-SULFAMOYLPHENYL)-2- (THIOPHEN-2-YL) ACETAMIDE  |   REVERSIBLE HYDRATION OF CARBONDIOXIDE, LYASE 
4fl7:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH N-(HYDROXY)-BENZAMIDE  |   LYASE 
4fpt:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH ETHYL (2Z,4R)-2- (SULFAMOYLIMINO)-1,3-THIAZOLIDINE-4-CARBOXYLATE  |   10 STRANDED TWISTED BETA-SHEETS, LYASE, LYASE-LYASE INHIBITOR COMPLEX 
3rg3:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE W5E MUTANT OF HUMAN CARBONIC ANHYDRASE II  |   ZINC METALLOENZYME, W5E MUTATION, LYASE 
3rg4:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE W5F MUTANT OF HUMAN CARBONIC ANHYDRASE II  |   ZINC METALLOENZYME, W5F MUTATION, LYASE 
4frc:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH N'-SULFAMOYLPYRROLIDINE-1- CARBOXIMIDAMIDE  |   10 STRANDED TWISTED BETA-SHEETS, LYASE, LYASE-LYASE INHIBITOR COMPLEX 
4fu5:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH N-[(2Z)-1,3-OXAZOLIDIN-2- YLIDENE]SULFURIC DIAMIDE  |   10 STRANDED TWISTED BETA-SHEETS, LYASE, LYASE-LYASE INHIBITOR COMPLEX 
4fvo:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH N-[(2E)-3,4-DIHYDROQUINAZOLIN- 2(1H)-YLIDENE]SULFURIC DIAMIDE  |   10 STRANDED TWISTED BETA-SHEETS, LYASE, LYASE-LYASE INHIBITOR COMPLEX 
3rj7:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH ITS INHIBITOR RHENIUM(I) TRISCARBONYL-CYCLOPENTADIENYL-CARBOXY-4-AMINOMETHYLBENZENE- SULFONAMIDE  |   INHIBITOR, TRANSITION METAL COMPLEX, ANHYDRASE, CARBON DIOXIDE, LYASE-LYASE INHIBITOR COMPLEX 
5jq0:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BENZOXABOROLE AT PH=8.7  |   BENZOXABOROLE, LYASE, BORON, ZINC, CARBONATE DEHYDRATASE 
5jqt:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BENZOXABOROLE AT PH 7.4  |   BENZOXABOROLE, LYASE, BORON, ZINC, CARBONATE DEHYDRATASE 
4g0c:A   (ALA115) to   (LEU212)  NEUTRON STRUCTURE OF ACETAZOLAMIDE-BOUND HUMAN CARBONIC ANHYDRASE II REVEAL MOLECULAR DETAILS OF DRUG BINDING.  |   CARBONIC ANHYDRASE, ACETAZOLAMIDE, HYDROGEN BONDING, LYASE-LYASE INHIBITOR COMPLEX 
4gl1:X   (ALA115) to   (LEU212)  STRUCTURE OF H64A/N62L/N67L HUMAN CARBONIC ANHYDRASE II TRIPLE MUTANT  |   MIXED ALPA BETA, LYASE 
5lmd:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF HCA II IN COMPLEX WITH A BENZOXABOROLE INHIBITOR  |   BENZOXABOROLE, ZINC ENZYME, INHIBITOR, LYASE 
6ca2:A   (ALA115) to   (LEU212)  ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE II  |   LYASE(OXO-ACID) 
7ca2:A   (ALA115) to   (LEU212)  ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE II  |   LYASE(OXO-ACID) 
3ryy:A   (ALA115) to   (LEU212)  FLUOROALKYL AND ALKYL CHAINS HAVE SIMILAR HYDROPHOBICITIES IN BINDING TO THE HYDROPHOBIC WALL OF CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
1avn:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH THE HISTAMINE ACTIVATOR  |   LYASE, OXO-ACID 
1bic:A   (ALA115) to   (LEU212)  CRYSTALLOGRAPHIC ANALYSIS OF THR-200-> HIS HUMAN CARBONIC ANHYDRASE II AND ITS COMPLEX WITH THE SUBSTRATE, HCO3-  |   LYASE(OXO-ACID) 
3s71:B   (ALA115) to   (LEU212)  THE ORIGIN OF THE HYDROPHOBIC EFFECT IN THE MOLECULAR RECOGNITION OF ARYLSULFONAMIDES BY CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
3s77:B   (ALA115) to   (LEU212)  THE ORIGIN OF THE HYDROPHOBIC EFFECT IN THE MOLECULAR RECOGNITION OF ARYLSULFONAMIDES BY CARBONIC ANHYDRASE  |   ALPHA BETA, LYASE 
1bzm:A   (SER115) to   (CYS212)  DRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I  |   PROTEIN-DRUG INTERACTIONS, OXO-ACID LYASE, SULFONAMIDES, LYASE(OXO- ACID) 
3ffp:X   (ALA115) to   (LEU212)  X RAY STRUCTURE OF THE COMPLEX BETWEEN CARBONIC ANHYDRASE II AND LC INHIBITORS  |   CARBONIC ANHYDRASE, INHIBITORS, CRYSTAL STRUCTURE, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL- BINDING, POLYMORPHISM, ZINC 
1ca2:A   (ALA115) to   (LEU212)  REFINED STRUCTURE OF HUMAN CARBONIC ANHYDRASE II AT 2.0 ANGSTROMS RESOLUTION  |   LYASE(OXO-ACID) 
1okn:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKN INHIBITOR 4- SULFONAMIDE-[1-(4-N-(5-FLUORESCEIN THIOUREA)BUTANE)]  |   LYASE (OXO-ACID), INHIBITOR 
1cnb:A   (ALA115) to   (LEU212)  COMPENSATORY PLASTIC EFFECTS IN THE REDESIGN OF PROTEIN- ZINC BINDING SITES  |   LYASE(OXO-ACID) 
1cnx:A   (ALA115) to   (LEU212)  SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS  |   LYASE (OXO-ACID) 
2q38:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH SACCHARIN AT 1.95 ANGSTROM  |   TEN STRANDED TWISTED BETA SHEET, LYASE 
1cva:A   (ALA115) to   (LEU212)  STRUCTURAL AND FUNCTIONAL IMPORTANCE OF A CONSERVED HYDROGEN BOND NETWORK IN HUMAN CARBONIC ANHYDRASE II  |   LYASE(OXO-ACID) 
1czm:A   (SER115) to   (CYS212)  DRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I  |   PROTEIN-DRUG INTERACTIONS, OXO-ACID LYASE, SULFONAMIDES, LYASE(OXO-ACID) 
4ilx:A   (ALA115) to   (LEU212)  STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH AN ADAMANTYL SULFONAMIDE INHIBITOR  |   LYASE, REVERSIBLE HYDRATION OF CARBON DIOXIDE, CYTOSOLIC, LYASE-LYASE INHIBITOR COMPLEX 
3t84:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH ACETYLATED CARBOHYDRATE SULFAMATES  |   ALPHA CARBONIC ANHYDRASE, LYASE-LYASE INHIBITOR COMPLEX 
3u7c:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE V143I MUTANT OF HUMAN CARBONIC ANHYDRASE II  |   LYASE, CARBONIC ANYDRASE C, CAC, SUBSTRATE BOUND, PRODUCT BOUND, CO2 PRESSURIZED, PRIMARILY BETA 
4z0q:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE INHIBITORS: DESIGN AND SYNTHESIS OF NEW HETEROARYL- N-CARBONYLBENZENESULFONAMIDES TARGETING DRUGGABLE HUMAN CARBONIC ANHYDRASE ISOFORMS (HCA VII, HCA IX, AND HCA XIV)  |   CARBONATE DEHYDRATASE II, CARBONIC ANHYDRASE C, CARBONIC ANHYDRASE II, CA-II, CARBONATE DEHYDRATASE II- INHIBITOR COMPLEX, LYASE 
1g1d:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEXED WITH 4-(AMINOSULFONYL)-N- [(2-FLUOROPHENYL)METHYL]-BENZAMIDE  |   CARBONIC ANHYDRASE II, 4-(AMINOSULFONYL)-N-[(2- FLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
4z1j:A   (ALA115) to   (LEU211)  CARBONIC ANHYDRASE INHIBITORS: DESIGN AND SYNTHESIS OF NEW HETEROARYL- N-CARBONYLBENZENESULFONAMIDES TARGETING DRUGGABLE HUMAN CARBONIC ANHYDRASE ISOFORMS (HCA VII, HCA IX, AND HCA XIV)  |   CARBONATE DEHYDRATASE II, CARBONIC ANHYDRASE C, CARBONIC ANHYDRASE II, CA-II, CARBONATE DEHYDRATASE II- INHIBITOR COMPLEX, LYASE 
1g46:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4- (AMINOSULFONYL)-N-[(2,3-DIFLUOROPHENYL)METHYL]-BENZAMIDE  |   CARBONIC ANHYDRASE II, F131V, 4-(AMINOSULFONYL)-N-[(2,3- DIFLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
1g48:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4- (AMINOSULFONYL)-N-[(2,6-DIFLUOROPHENYL)METHYL]-BENZAMIDE  |   CARBONIC ANHYDRASE II, F131V, 4-(AMINOSULFONYL)-N-[(2,6- DIFLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
1g4j:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4- (AMINOSULFONYL)-N-[(2,3,4,5,6-PENTAFLUOROPHENYL)METHYL]- BENZAMIDE  |   CARBONIC ANHYDRASE II, F131V, 4-(AMINOSULFONYL)-N-[(2,3,4,5, 6-PENTAFLUOROPHENYL)METHYL]-BENZAMIDE, LYASE 
1rza:A   (ALA115) to   (LEU212)  X-RAY ANALYSIS OF METAL SUBSTITUTED HUMAN CARBONIC ANHYDRASE II DERIVATIVES  |   LYASE(OXO-ACID) 
4knj:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 2- CHLORO-4-[(PYRIMIDIN-2-YLSULFANYL)ACETYL]BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4kuy:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH THE 5-(3-(O-TOLYLSULFONYL)UREIDO)PYRIDINE-2-SULFONAMIDE INHIBITOR  |   LYASE, LYASE-LYASE INHIBITOR COMPLEX 
3ibl:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH AN ALIPHATIC BIS-SULFAMATE INHIBITOR  |   CARBONIC ANHYDRASE II, PROTEIN-INHIBITOR COMPLEX, ALIPHATIC BIS- SULFAMATE INHIBITOR, DISEASE MUTATION, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4l5w:A   (ALA115) to   (LEU212)  STRUCTURAL IMPLICATIONS OF THE SECONDARY CO2 BINDING POCKET IN HUMAN CARBONIC ANHYDRASE II  |   ALLOSTERIC REGULATION, THERMOSTABILITY, LYASE 
1tg3:A   (ALA115) to   (LEU212)  EFFECT OF SHUTTLE LOCATION AND PH ENVIRONMENT ON H+ TRANSFER IN HUMAN CARBONIC ANHYDRASE II  |   PROTON SHUTTLE CARBONIC ANHYDRASE METALLOENZYME, LYASE 
1hea:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II (CARBONATE DEHYDRATASE) (HCA II) (E.C.4.2.1.1) MUTANT WITH LEU 198 REPLACED BY ARG (L198R)  |   LYASE(OXO-ACID) 
1hec:A   (ALA115) to   (LEU212)  STRUCTURAL CONSEQUENCES OF HYDROPHILIC AMINO-ACID SUBSTITUTIONS IN THE HYDROPHOBIC POCKET OF HUMAN CARBONIC ANHYDRASE II  |   LYASE(OXO-ACID) 
4zwi:A   (ALA115) to   (LEU212)  SURFACE LYSINE ACETYLATED HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A SULFAMATE-BASED INHIBITOR  |   ACETYLATED LYSINES, SULFAMATE-BASED INHIBITOR, LYASE-LYASE INHIBITOR COMPLEX 
2hnc:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH THE 5-AMINO-1,3,4-THIADIAZOLE-2-SULFONAMIDE INHIBITOR.  |   PROTEIN-INHIBITOR COMPLEX, LYASE 
1i8z:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II COMPLEXED WITH AL-6629 2H-THIENO[3,2- E]-1,2-THIAZINE-6-SULFONAMIDE, 2-(3-METHOXYPHENYL)-3-(4- MORPHOLINYL)-, 1,1-DIOXIDE  |   CARBONIC ANHYDRASE II, AL-6629, LYASE 
1ugb:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY GLY (A65G)  |   LYASE (OXO-ACID), ACETYLATION, ZINC, POLYMORPHISM, DISEASE MUTATION 
4m2u:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH DORZOLAMIDE  |   LYASE-LYASE INHIBITOR COMPLEX 
4mdl:A   (ALA115) to   (LEU212)  META CARBORANE CARBONIC ANHYDRASE INHIBITOR  |   CARBONIC ANHYDRASE INHIBITOR COMPLEX, LYASE-LYASE INHIBITOR COMPLEX 
1j9w:A   (SER115) to   (CYS212)  SOLUTION STRUCTURE OF THE CAI MICHIGAN 1 VARIANT  |   10-STRANDED-BETA-SHEET, LYASE 
1jv0:A   (SER115) to   (CYS212)  THE CRYSTAL STRUCTURE OF THE ZINC(II) ADDUCT OF THE CAI MICHIGAN 1 VARIANT  |   10-STRANDED-BETA-SHEET, LYASE 
2nnv:A   (ALA115) to   (LEU212)  STRUCTURE OF INHIBITOR BINDING TO CARBONIC ANHYDRASE II  |   ZINC METALLOENZYME, SULFONAMIDE, LYASE 
3jxg:B   (PRO171) to   (ARG271)  CA-LIKE DOMAIN OF MOUSE PTPRG  |   CA-LIKE DOMAIN, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PHOSPHOPROTEIN, PROTEIN PHOSPHATASE, TRANSMEMBRANE, CELL ADHESION 
3jxg:D   (PRO171) to   (PHE270)  CA-LIKE DOMAIN OF MOUSE PTPRG  |   CA-LIKE DOMAIN, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PHOSPHOPROTEIN, PROTEIN PHOSPHATASE, TRANSMEMBRANE, CELL ADHESION 
3jxf:A   (PRO150) to   (PHE249)  CA-LIKE DOMAIN OF HUMAN PTPRZ  |   CA-LIKE DOMAIN, ALTERNATIVE SPLICING, GLYCOPROTEIN, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEIN PHOSPHATASE, TRANSMEMBRANE, CELL ADHESION 
3jxf:B   (PRO150) to   (PHE249)  CA-LIKE DOMAIN OF HUMAN PTPRZ  |   CA-LIKE DOMAIN, ALTERNATIVE SPLICING, GLYCOPROTEIN, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEIN PHOSPHATASE, TRANSMEMBRANE, CELL ADHESION 
2nwy:A   (ALA115) to   (LEU212)  STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS ON THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II  |   PROTON TRANSFER, HISTIDINE 64, CARBONIC ANHYDRASE, LYASE 
3k34:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II WITH A SULFONAMIDE INHIBITOR  |   CARBONIC ANHYDRASE, ATOMIC RESOLUTION, SULFONAMIDE INHIBITOR, DISEASE MUTATION, LYASE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3k7k:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBONIC ANHYDRASE II AND ANIONS  |   INORGANIC ANION, TRITHIOCARBONATE, X RAY, CARBONIC ANHYDRASE II 
1ydc:A   (ALA115) to   (LEU212)  STRUCTURAL BASIS OF INHIBITOR AFFINITY TO VARIANTS OF HUMAN CARBONIC ANHYDRASE II  |   HYDRO-LYASE 
1yo0:A   (ALA115) to   (LEU211)  PROTON TRANSFER FROM HIS200 IN HUMAN CARBONIC ANHYDRASE II  |   PROTON TRANSFER, HUMAN CARBONIC ANHYDRASE, LYASE 
1yo1:A   (ALA115) to   (LEU211)  PROTON TRANSFER FROM HIS200 IN HUMAN CARBONIC ANHYDRASE II  |   PROTON TRANSFER HUMAN CARBONIC ANHYDRASE, LYASE 
3l14:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH ALTHIAZIDE  |   LYASE, CARBONIC ANHYDRASE II, ALTHIAZIDE, 6-CHLORO-3, 4-DIHYDRO-3- ((2-PROPENYLTHIO)METHYL)-2H-1, 2, 4-BENZOTHIADIAZINE-7-SULFONAMIDE, DISEASE MUTATION, METAL-BINDING 
5dsj:A   (ALA115) to   (LEU212)  STRUCTURE OF CO2 RELEASED HOLO-FORM OF HUMAN CARBONIC ANHYDRASE II WITH 50 SEC WARMING  |   CARBONIC ANHYDRASE II, CO2 RELEASE, INTERMEDIATE STATES, LYASE 
1ze8:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH A MEMBRANE-IMPERMEANT SULFONAMIDE INHIBITOR  |   TWISTED BETA-SHEET, LYASE 
4q78:A   (ALA115) to   (LEU212)  STRUCTURE-ASSISTED DESIGN OF CARBORANE-BASED INHIBITORS OF CARBONIC ANHYDRASE  |   CARBONIC ANHYDRASE, LYASE-LYASE INHIBITOR COMPLEX 
4qiy:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4qiy:B   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4qiy:C   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
4qiy:D   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH INHIBITOR  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3mdz:A   (PRO117) to   (LEU214)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE VII [ISOFORM 1], CA7  |   CARBONIC ANHYDRASE VII, CA7, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, CYTOPLASM, LYASE, METAL-BINDING, ZINC 
3mhc:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CABONIC ANHYDRASE II IN ADDUCT WITH AN ADAMANTYL ANALOGUE OF ACETAZOLAMIDE IN A NOVEL HYDROPHOBIC BINDING POCKET  |   CARBONIC ANHYDRASE INHIBITORS, ADAMANTYL, ACETAZOLAMIDE, LYASE 
3mhl:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 4-{[N- (6-METHOXY-5-NITROPYRIMIDIN-4-YL)AMINO]METHYL}BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, SULFONAMIDE, LYASE-LYASE INHIBITOR COMPLEX 
3ml2:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDSASE II IN COMPLEX WITH AN ARYL SULFONAMIDE INHIBITOR  |   ZINC METALLOENZYME, METAL-BINDING, LYASE,SULFONAMIDE, ZINC LIGANDS, INHIBITOR, LYASE, LYASE-LYASE INHIBITOR COMPLEX 
3ml5:A   (PRO115) to   (LEU212)  CRYSTAL STRUCTURE OF THE C183S/C217S MUTANT OF HUMAN CA VII IN COMPLEX WITH ACETAZOLAMIDE  |   PROTEIN-INHIBITOR COMPLEX, LYASE 
3bet:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH STX 641 AT 1.85 ANGSTROMS RESOLUTION  |   PROTEIN-INHIBITOR COMPLEX, DISEASE MUTATION, LYASE, METAL-BINDING 
4bf1:A   (ALA115) to   (LEU212)  THREE DIMENSIONAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 5-(1-NAPHTHALEN-1-YL-1,2,3-TRIAZOL-4-YL) THIOPHENE-2-SULFONAMIDE  |   LYASE 
4qsa:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE ISOZYME II WITH 2- CHLORO-4-{[(4-METHYL-6-OXO-1,6-DIHYDROPYRIMIDIN-2-YL) THIO]ACETYL}BENZENESULFONAMIDE  |   DRUG DESIGN, CARBONIC ANHYDRASE, BENZENESULFONAMIDE, METAL-BINDING, LYASE-LYASE INHIBITOR COMPLEX 
3mnh:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II MUTANT K170A  |   PROTON TRANSFER, METALLOENZYME, PROTON TRANSPORT 
3mnu:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE INHIBITORS: CRYSTALLOGRAPHIC AND SOLUTION BINDING STUDIES FOR THE INTERACTION OF A BORON CONTAINING AROMATIC SULFAMIDE WITH MAMMALIAN ISOFORMS I-XV  |   PROTEIN-INHIBITOR COMPLEX, LYASE 
3bl1:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE INHIBITORS. SULFONAMIDE DIURETICS REVISITED OLD LEADS FOR NEW APPLICATIONS  |   CARBONIC ANHYDRASE, INHIBITORS, CRYSTAL STRUCTURE, DIURETICS, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL-BINDING, POLYMORPHISM, ZINC, LYASE(OXO-ACID) 
4qy3:A   (ALA115) to   (LEU212)  THE CRYSTAL STRUCTURE OF THE COMPLEX OF HCAII WITH AN ORTHO- SUBSTITUTED BENZOIC ACID  |   CARBONIC ANHYDRASE II, LYASE, LYASE-LYASE INHIBITOR COMPLEX 
3n3j:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A BENZENESULFONAMIDE INHIBITOR  |   LYASE, METALLOENZYME, ZINC LIGANDS, BENZENESULFONAMIDE, INHIBITOR, GLYCEROL, LYASE-LYASE INHIBITOR COMPLEX 
3n4b:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A BENZENESULFONAMIDE INHIBITOR  |   LYASE, ZINC METALLOENZYME, ZINC LIGANDS, BENZENESULFONAMIDE, INHIBITOR, LYASE-LYASE INHIBITOR COMPLEX 
5fdi:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II WITH THE ANTICONVULSANT SULFAMIDE JNJ-26990990 AND ITS S,S-DIOXIDE ANALOG.  |   SULFAMIDE INHIBITOR, PROTEIN-INHIBITOR COMPLEX, LYASE 
3nb5:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 2-(3-CHLORO-4- HYDROXYPHENYL)-N-(4-SULFAMOYLPHENETHYL)ACETAMIDE  |   DRUG DESIGN, NATURAL PRODUCT, SULFAMATE, LYASE-LYASE INHIBITOR COMPLEX 
5flr:A   (ALA115) to   (LEU212)  NATIVE STATE MASS SPECTROMETRY, SURFACE PLASMON RESONANCE AND X-RAY CRYSTALLOGRAPHY CORRELATE STRONGLY AS A FRAGMENT SCREENING COMBINATION  |   LYASE, FRAGMENTS, METALLOPROTEIN 
5fls:A   (ALA115) to   (LEU212)  NATIVE STATE MASS SPECTROMETRY, SURFACE PLASMON RESONANCE AND X-RAY CRYSTALLOGRAPHY CORRELATE STRONGLY AS A FRAGMENT SCREENING COMBINATION  |   LYASE, FRAGMENTS, METALLOPROTEIN 
5flt:A   (ALA115) to   (LEU212)  NATIVE STATE MASS SPECTROMETRY, SURFACE PLASMON RESONANCE AND X-RAY CRYSTALLOGRAPHY CORRELATE STRONGLY AS A FRAGMENT SCREENING COMBINATION  |   LYASE, FRAGMENTS, CARBONIC ANHYDRASE, METALLOPROTEIN 
5fni:A   (ALA115) to   (LEU212)  NATIVE STATE MASS SPECTROMETRY, SURFACE PLASMON RESONANCE AND X-RAY CRYSTALLOGRAPHY CORRELATE STRONGLY AS A FRAGMENT SCREENING COMBINATION  |   LYASE, FRAGMENTS, CARBONIC ANHYDRASE, METALLOPROTEIN 
4ca2:A   (ALA115) to   (LEU212)  ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE II  |   LYASE(OXO-ACID) 
4cnr:A   (ALA115) to   (LEU211)  SURFACE RESIDUE ENGINEERING OF BOVINE CARBONIC ANHYDRASE TO AN EXTREME HALOPHILIC ENZYME FOR POTENTIAL APPLICATION IN POSTCOMBUSTION CO2 CAPTURE  |   LYASE, PROTEIN ENGINEERING, CO2 CAPTURE 
4cnr:B   (ALA115) to   (LEU211)  SURFACE RESIDUE ENGINEERING OF BOVINE CARBONIC ANHYDRASE TO AN EXTREME HALOPHILIC ENZYME FOR POTENTIAL APPLICATION IN POSTCOMBUSTION CO2 CAPTURE  |   LYASE, PROTEIN ENGINEERING, CO2 CAPTURE 
4cnr:C   (ALA115) to   (LEU211)  SURFACE RESIDUE ENGINEERING OF BOVINE CARBONIC ANHYDRASE TO AN EXTREME HALOPHILIC ENZYME FOR POTENTIAL APPLICATION IN POSTCOMBUSTION CO2 CAPTURE  |   LYASE, PROTEIN ENGINEERING, CO2 CAPTURE 
4cnr:D   (ALA115) to   (LEU211)  SURFACE RESIDUE ENGINEERING OF BOVINE CARBONIC ANHYDRASE TO AN EXTREME HALOPHILIC ENZYME FOR POTENTIAL APPLICATION IN POSTCOMBUSTION CO2 CAPTURE  |   LYASE, PROTEIN ENGINEERING, CO2 CAPTURE 
5g0b:A   (ALA115) to   (LEU212)  AN UNUSUAL NATURAL PRODUCT PRIMARY SULFONAMIDE: SYNTHESIS, CARBONIC ANHYDRASE INHIBITION AND PROTEIN X-RAY STRUCTURE OF PSAMMAPLIN C  |   LYASE, PROTEIN ENGINEERING, NATURAL PRODUCT INHIBITOR, CARBONIC ANHYDRASE 
3dc3:A   (ALA115) to   (LEU212)  USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES  |   CARBONIC ANHYDRASE II COMPLEX, CAIX MIMIC INHIBITORS, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL- BINDING, POLYMORPHISM, ZINC 
3dd0:A   (ALA115) to   (LEU212)  USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES  |   CARBONIC ANHYDRASE II COMPLEX, CAIX MIMIC INHIBITORS, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL- BINDING, POLYMORPHISM, ZINC 
3dd8:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE INHIBITORS. INTERACTION OF THE ANTITUMOR SULFAMATE EMD-486019 WITH TWELVE MAMMALIAN ISOFORMS: KINETIC AND X-RAY CRYSTALLOGRAPHIC STUDIES  |   CARBONIC ANHYDRASE, INHIBITORS, CRYSTAL STRUCTURE, ANTIGLAUCOMA, OAO-ACID, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL-BINDING, POLYMORPHISM, ZINC 
3dv7:A   (ALA115) to   (LEU212)  ROLE OF HYDROPHILIC RESIDUES IN PROTON TRANSFER DURING CATALYSIS BY HUMAN CARBONIC ANHYDRASE II (N62A)  |   HCA II, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL-BINDING, POLYMORPHISM, ZINC 
3dvb:A   (ALA115) to   (LEU212)  X-RAY CRYSTAL STRUCTURE OF MUTANT N62V HUMAN CARBONIC ANHYDRASE II  |   HUMAN CARBONIC ANHYDRASE II, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL-BINDING, POLYMORPHISM, ZINC 
3dvc:A   (ALA115) to   (LEU212)  X-RAY CRYSTAL STRUCTURE OF MUTANT N62T OF HUMAN CARBONIC ANHYDRASE II  |   HUMAN CARBONIC ANHYDRASE, ACETYLATION, CYTOPLASM, DISEASE MUTATION, LYASE, METAL-BINDING, POLYMORPHISM, ZINC 
3oy0:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH 1-(4-(4-(2- (ISOPROPYLSULFONYL)PHENYLAMINO)-1H-PYRROLO[2,3-B]PYRIDIN-6-YLAMINO)- 3-METHOXYPHENYL)PIPERIDIN-4-OL  |   BENZENE SULFONAMIDE, DRUG INTERACTION, LYASE-LYASE INHIBITOR COMPLEX 
3p3h:A   (ALA115) to   (LEU211)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH P-(5-FERROCENYL-1H-1,2,3- TRIAZOL-1-YL)BENZENESULFONAMIDE  |   CARBONIC ANHYDRASE ALPHA, LYASE, CYTOSOLIC 
3po6:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II WITH 6,7-DIMETHOXY-1- METHYL-3,4-DIHYDROISOQUINOLINE-2(1H)-SULFONAMIDE  |   CARBONIC ANHYDRASE, LYASE-LYASE INHIBITOR COMPLEX 
5j8z:A   (ALA115) to   (LEU212)  HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH LIGAND  |   CYTOPLASM, LYASE, 2-THIO-6-OXO-1, 6-DIHYDROPYRIMIDINES, SULFONAMIDES 
3rge:A   (ALA115) to   (LEU212)  CRYSTAL STRUCTURE OF THE W5H MUTANT OF HUMAN CARBONIC ANHYDRASE II  |   ZINC METALLOENZYME, W5H MUTATION, LYASE 
4fvn:A   (ALA115) to   (LEU212)  CARBONIC ANHYDRASE II IN COMPLEX WITH N-(TETRAHYDROPYRIMIDIN-2(1H)- YLIDENE)SULFURIC DIAMIDE  |   10 STRANDED TWISTED BETA-SHEETS, LYASE, LYASE-LYASE INHIBITOR COMPLEX 
8ca2:A   (ALA115) to   (LEU212)  ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE II  |   LYASE(OXO-ACID)