1n9b:A (ALA217) to (HIS289) ULTRAHIGH RESOLUTION STRUCTURE OF A CLASS A BETA-LACTAMASE: ON THE MECHANISM AND SPECIFICITY OF THE EXTENDED-SPECTRUM SHV-2 ENZYME | BETA-LACTAM HYDROLASE, PENICILLINASE, DETERGENT BINDING, DRUG DESIGN, RADIATION DAMAGE
2ajr:A (THR207) to (ILE272) CRYSTAL STRUCTURE OF POSSIBLE 1-PHOSPHOFRUCTOKINASE (EC 2.7.1.56) (TM0828) FROM THERMOTOGA MARITIMA AT 2.46 A RESOLUTION | TM0828, POSSIBLE 1-PHOSPHOFRUCTOKINASE (EC 2.7.1.56), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI, TRANSFERASE
3eaz:A (THR88) to (ASP159) CRYSTAL STRUCTURE OF SH2 DOMAIN OF HUMAN CSK (CARBOXYL-TERMINAL SRC KINASE), C122S MUTANT. | SH2, CSK, DISULFIDE, OXIDIZED REDUCED, ATP-BINDING, CELL MEMBRANE, KINASE, MEMBRANE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SH2 DOMAIN, SH3 DOMAIN, TRANSFERASE, TYROSINE-PROTEIN KINASE
3egx:C (GLN31) to (GLN98) CRYSTAL STRUCTURE OF THE MAMMALIAN COPII-COAT PROTEIN SEC23A/24A COMPLEXED WITH THE SNARE PROTEIN SEC22B AND BOUND TO THE TRANSPORT SIGNAL SEQUENCE OF THE SNARE PROTEIN BET1 | COPII COAT PROTEIN, VESICLE TRANSPORT, TRANSPORT SIGNAL SEQUENCE, DISEASE MUTATION, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, GOLGI APPARATUS, MEMBRANE, PROTEIN TRANSPORT, TRANSPORT, PHOSPHOPROTEIN, TRANSMEMBRANE
2b18:A (PRO72) to (LEU155) N-TERMINAL GAF DOMAIN OF TRANSCRIPTIONAL PLEIOTROPIC REPRESSOR CODY. | CODY, DNA-BINDING; NUCLEOTIDE-BINDING; REPRESSOR; TRANSCRIPTION REGULATION; GAF DOMAIN; BRANCHED CHAIN AMINO ACID BINDING.
1ayb:A (THR12) to (HIS84) CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO- TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE | HYDROLASE(SH2 DOMAIN)
1ayc:A (THR12) to (HIS84) CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO- TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE | HYDROLASE(SH2 DOMAIN)
1ayd:A (THR12) to (HIS84) CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO- TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE | HYDROLASE(SH2 DOMAIN)
1bfj:A (ASN17) to (THR88) SOLUTION STRUCTURE OF THE C-TERMINAL SH2 DOMAIN OF THE P85ALPHA REGULATORY SUBUNIT OF PHOSPHOINOSITIDE 3-KINASE, NMR, MINIMIZED AVERAGE STRUCTURE | SH2 DOMAIN, P85ALPHA, PI 3-KINASE, NMR, C TERMINAL SH2 DOMAIN
4hmy:S (ASP25) to (PHE95) STRUCTURAL BASIS FOR RECRUITMENT AND ACTIVATION OF THE AP-1 CLATHRIN ADAPTOR COMPLEX BY ARF1 | PROTEIN TRANSPORT, PROTEIN TRAFFICKING, ARF1 GTPASE ACTIVATION, ARF1 GTPASE BINDING, TRANS-GOLGI MEMBRANE
1blh:A (LEU220) to (PHE290) STRUCTURE OF A PHOSPHONATE-INHIBITED BETA-LACTAMASE. AN ANALOG OF THE TETRAHEDRAL TRANSITION STATE(SLASH) INTERMEDIATE OF BETA-LACTAM HYDROLYSIS | HYDROLASE(BETA-LACTAMASE)
1blp:A (GLY217) to (PHE290) STRUCTURAL BASIS FOR THE INACTIVATION OF THE P54 MUTANT OF BETA- LACTAMASE FROM STAPHYLOCOCCUS AUREUS PC1 | HYDROLASE(ACTING ON CYCLIC AMIDES)
4x69:A (SER220) to (HIS288) CRYSTAL STRUCTURE OF OP0595 COMPLEXED WITH CTX-M-44 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3sh7:B (GLY217) to (LEU290) CRYSTAL STRUCTURE OF FLUOROPHORE-LABELED BETA-LACTAMASE PENP | BETA-LACTAMASE, FLUOROPHORE, BETA-LACTAM, HYDROLASE
3sh9:B (GLY217) to (ALA289) CRYSTAL STRUCTURE OF FLUOROPHORE-LABELED BETA-LACTAMASE PENP IN COMPLEX WITH CEFOTAXIME | PENP, BETA-LACTAMASE, CEFOTAXIME, FLUOROPHORE, HYDROLASE-ANTIBIOTIC COMPLEX
1ome:B (GLY217) to (MET287) CRYSTAL STRUCTURE OF THE OMEGA LOOP DELETION MUTANT (RESIDUES 163-178 DELETED) OF BETA-LACTAMASE FROM STAPHYLOCOCCUS AUREUS PC1 | HYDROLASE, BETA-LACTAMASE, BETA-LACTAM ANTIBIOTIC RESISTANCE
1ong:A (ALA217) to (HIS289) SHV-1 BETA-LACTAMASE WITH A PENEM INHIBITOR | BETA-LACTAM HYDROLASE, PENICILLINASE, DETERGENT BINDING, DRUG DESIGN
3soi:A (LEU220) to (ASN291) CRYSTALLOGRAPHIC STRUCTURE OF BACILLUS LICHENIFORMIS BETA-LACTAMASE W210F/W229F/W251F AT 1.73 ANGSTROM RESOLUTION | HYDROLASE, (ACTING IN CYCLIC AMIDES)
3soi:B (LEU220) to (LEU290) CRYSTALLOGRAPHIC STRUCTURE OF BACILLUS LICHENIFORMIS BETA-LACTAMASE W210F/W229F/W251F AT 1.73 ANGSTROM RESOLUTION | HYDROLASE, (ACTING IN CYCLIC AMIDES)
1csz:A (ARG22) to (LYS94) SYK TYROSINE KINASE C-TERMINAL SH2 DOMAIN COMPLEXED WITH A PHOSPHOPEPTIDEFROM THE GAMMA CHAIN OF THE HIGH AFFINITY IMMUNOGLOBIN G RECEPTOR, NMR | PROTEIN-TYROSINE KINASE SH2 DOMAIN, COMPLEX (PHOSPHOTRANSFERASE- PEPTIDE), COMPLEX (PHOSPHOTRANSFERASE-PEPTIDE) COMPLEX
3g2y:B (SER220) to (LEU290) CTX-M-9 CLASS A BETA-LACTAMASE COMPLEXED WITH COMPOUND 1 (GF4) | CTX-M, BETA-LACTAMASE, MOLECULAR DOCKING, FRAGMENT, INHIBITOR, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3g35:B (GLY217) to (LEU290) CTX-M-9 CLASS A BETA-LACTAMASE COMPLEXED WITH COMPOUND 12 (F13) | CTX-M, BETA-LACTAMASE, MOLECULAR DOCKING, FRAGMENT, INHIBITOR, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3t12:B (LEU56) to (LEU137) MGLA IN COMPLEX WITH MGLB IN TRANSITION STATE | G-DOMAIN CONTAINING PROTEIN, BACTERIAL POLARITY, MOTILITY, HOMODIMERIC GAP PROTEIN, POLE LOCALISATION, ALPHA/BETA PROTEINS, GTPASE, HYDROLASE-SIGNALING PROTEIN COMPLEX
3t1q:C (LEU56) to (ALA136) MGLA BOUND TO GPPNHP IN COMPLEX WITH MGLB | G DOMAIN CONTAINING PROTEIN, BACTERIAL GTPASE, BACTERIAL POLARITY, MOTILITY, GTPASE ACTIVATING PROTEIN, ALPHA/BETA PROTEINS, HOMODIMER, POLE LOCALISATION, HYDROLASE-SIGNALING PROTEIN COMPLEX
3t1s:A (LEU56) to (LEU137) MGLB HOMODIMER | GTPASE ACTIVATING PROTEIN, BACTERIAL POLARITY, MOTILITY, POLE LOCALISATION, ALPHA/BETA PROTEIN, CATALYTIC GAP DOMAIN, HOMODIMER, SIGNALING PROTEIN
1dio:B (ASP112) to (ARG178) DIOL DEHYDRATASE-CYANOCOBALAMIN COMPLEX FROM KLEBSIELLA OXYTOCA | COENZYME B12, PROPANEDIOL, POTASSIUM ION, TIM BARREL, LYASE
1djc:A (GLY217) to (PHE290) STRUCTURE OF BETA-LACTAMASE PRECURSOR, S70A MUTANT, AT 120K | HYDROLASE, ANTIBIOTIC RESISTANCE, SIGNAL, PLASMID, TRANSPOSABLE ELEMENT
1dja:A (LEU220) to (PHE290) STRUCTURE OF BETA-LACTAMASE PRECURSOR, K73H MUTANT, AT 298K | HYDROLASE, ANTIBIOTIC RESISTANCE
2cr4:A (GLU25) to (VAL104) SOLUTION STRUCTURE OF THE SH2 DOMAIN OF HUMAN SH3BP2 PROTEIN | SH2 DOMAIN, 3BP-2, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, SIGNALING PROTEIN
1pic:A (ASN18) to (THR89) PHOSPHATIDYLINOSITOL 3-KINASE, P85-ALPHA SUBUNIT: C- TERMINAL SH2 DOMAIN COMPLEXED WITH A TYR751 PHOSPHOPEPTIDE FROM THE PDGF RECEPTOR, NMR, MINIMIZED MEAN STRUCTURE | PHOSPHOTRANSFERASE, SH2 DOMAIN, SIGNAL TRANSDUCTION, PHOSPHOINOSITIDE 3-KINASE, COMPLEX (PHOSPHOTRANSFERASE/RECEPTOR)
2qzi:D (HIS10) to (LYS72) THE CRYSTAL STRUCTURE OF A CONSERVED PROTEIN OF UNKNOWN FUNCTION FROM STREPTOCOCCUS THERMOPHILUS LMG 18311. | APC86636, STREPTOCOCCUS THERMOPHILUS LMG 18311, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
3tkz:A (THR12) to (HIS84) STRUCTURE OF THE SHP-2 N-SH2 DOMAIN IN A 1:2 COMPLEX WITH RVIPYFVPLNR PEPTIDE | SH2 DOMAIN, PROTEIN PROTEIN INTERACTIONS, PTR RESIDUES, HYDROLASE- PEPTIDE COMPLEX
4je4:A (THR12) to (HIS85) CRYSTAL STRUCTURE OF MONOBODY NSA1/SHP2 N-SH2 DOMAIN COMPLEX | ENGINEERED BINDING PROTEIN, SHP2 SH2-MONOBODY COMPLEX, PHOSPHATASE, PHOSPHOTYROSINE BINDING, PHOSPHORYLATION, SIGNALING PROTEIN-PROTEIN BINDING COMPLEX
1egm:E (ASP112) to (LYS177) CRYSTAL STRUCTURE OF DIOL DEHYDRATASE-CYANOCOBALAMIN COMPLEX AT 100K. | CYANOCOBALAMIN, PROPANEDIOL, POTASSIUM ION, TIM BARREL, LYASE
3toi:A (LEU220) to (GLY289) TAILORING ENZYME STABILITY AND EXPLOITING STABILITY-TRAIT LINKAGE BY ITERATIVE TRUNCATION AND OPTIMIZATION | HYDROLASE
3trc:A (GLY75) to (GLY163) STRUCTURE OF THE GAF DOMAIN FROM A PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE (PTSP) FROM COXIELLA BURNETII | SIGNAL TRANSDUCTION, TRANSFERASE
4jpm:A (ALA217) to (HIS289) STRUCTURE OF SHV-1 BETA-LACTAMASE IN COMPLEX WITH THE 7- ALKYLIDENECEPHALOSPORIN DCM-1-10 AT 1.14 ANG RESOLUTION | CLASS A BETA-LACTAMASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1f5m:A (VAL100) to (SER176) STRUCTURE OF THE GAF DOMAIN | GAF, CGMP BINDING, SIGNALING PROTEIN
1f5m:B (VAL100) to (SER176) STRUCTURE OF THE GAF DOMAIN | GAF, CGMP BINDING, SIGNALING PROTEIN
4ynr:A (GLY119) to (ALA203) DOSS GAFA DOMAIN REDUCED CO BOUND CRYSTAL STRUCTURE | DOSS, TUBERCULOSIS, HEME, GAS SENSOR, OXIDOREDUCTASE
4ynr:B (GLY119) to (ALA203) DOSS GAFA DOMAIN REDUCED CO BOUND CRYSTAL STRUCTURE | DOSS, TUBERCULOSIS, HEME, GAS SENSOR, OXIDOREDUCTASE
1fhs:A (PRO15) to (THR87) THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SRC HOMOLOGY DOMAIN-2 OF THE GROWTH FACTOR RECEPTOR BOUND PROTEIN-2, NMR, 18 STRUCTURES | GRB2, SH2 DOMAIN, PROTEIN NMR, SOLUTION STRUCTURES
3uf4:A (ARG156) to (LYS234) CRYSTAL STRUCTURE OF A SH3 AND SH2 DOMAINS OF FYN PROTEIN (PROTO- CONCOGENE TYROSINE-PROTEIN KINASE FYN) FROM MUS MUSCULUS AT 1.98 A RESOLUTION | PHOSPHORYLATION, HOST-VIRUS INTERACTION, PROTEIN-TYROSINE KINASES, SRC HOMOLOGY DOMAINS, SRC-FAMILY KINASES, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, TRANSFERASE, PARTNERSHIP FOR T-CELL BIOLOGY
1rcj:A (ALA217) to (HIS289) CRYSTAL STRUCTURE OF E166A MUTANT OF SHV-1 BETA-LACTAMASE WITH THE TRANS-ENAMINE INTERMEDIATE OF TAZOBACTAM | BETA-LACTAMASE, BETA-LACTAM HYDROLASE, PENICILLINASE, DETERGENT BINDING, INHIBITOR DESIGN, COVALENT INTERMEDIATE
3us4:A (SER128) to (ASP199) CRYSTAL STRUCTURE OF A SH2 DOMAIN OF A MEGAKARYOCYTE-ASSOCIATED TYROSINE KINASE (MATK) FROM HOMO SAPIENS AT 1.50 A RESOLUTION | SH2 DOMAIN, SIGNALING PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, TRANSFERASE, PARTNERSHIP FOR T-CELL BIOLOGY
2vks:A (ASN292) to (SER373) CRYSTAL STRUCTURE OF GAF-B DOMAIN OF DEVS FROM MYCOBACTERIUM SMEGMATIS | GAF, HYPOXIA SENSING, HISTIDINE KINASE, HYDROLASE
4zam:A (ALA217) to (GLU288) CRYSTAL STRUCTURE OF SHV-1 BETA-LACTAMASE BOUND TO AVIBACTAM | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3huo:B (GLY217) to (LEU290) X-RAY CRYSTALLOGRAPHIC STRUCTURE OF CTX-M-9 S70G IN COMPLEX WITH BENZYLPENICILLIN | BETA-LACTAMASE, BLSE, CTX-M-9, B-LACTAM, PENICILLIN, BENZYLPENICILLIN, HYDROLASE
1ghm:A (LEU220) to (PHE290) STRUCTURES OF THE ACYL-ENZYME COMPLEX OF THE STAPHYLOCOCCUS AUREUS BETA-LACTAMASE MUTANT GLU166ASP:ASN170GLN WITH DEGRADED CEPHALORIDINE | HYDROLASE, ANTIBIOTIC RESISTANCE, BETA-LACTAM HYDROLYSIS, BENZYLPENICILLIN, CEPHALORIDINE
3v50:A (ALA217) to (HIS289) COMPLEX OF SHV S130G MUTANT BETA-LACTAMASE COMPLEXED TO SA2-13 | CLASS A BETA-LACTAMASE FOLD, HYDROLYZE B-LACTAM ANTIBIOTICS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3v5m:A (ASP214) to (HIS289) CRYSTAL STRUCTURE OF M69V MUTANT OF SHV BETA-LACTAMASE | CLASS A BETA-LACTAMASE FOLD, HYDROLYZE B-LACTAM ANTIBIOTICS, HYDROLASE
1sko:A (ARG47) to (ALA112) MP1-P14 COMPLEX | MAP KINASE PATHWAY, MP1-P14 COMPLEX, SCAFFOLD PROTEINS, SIGNALING PROTEIN
1spr:D (THR11) to (HIS90) BINDING OF A HIGH AFFINITY PHOSPHOTYROSYL PEPTIDE TO THE SRC SH2 DOMAIN: CRYSTAL STRUCTURES OF THE COMPLEXED AND PEPTIDE-FREE FORMS | TRANSFERASE(PHOSPHOTRANSFERASE)
3vff:C (GLY217) to (LEU292) BLAC E166A CDC-OME ACYL-INTERMEDIATE COMPLEX | BETA-LACTAMASE, SERINE HYDROLASE, SERINE ESTERASE, ACYL-INTERMEDIATE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vfh:C (GLY217) to (LEU292) BLAC E166A CDC-1 ACYL-INTERMEDIATE | BETA-LACTAMASE, SERINE HYDROLASE, SERINE ESTERASE, ACYL-INTERMEDIATE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2gk4:A (THR164) to (TYR227) THE CRYSTAL STRUCTURE OF THE DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN FROM STREPTOCOCCUS PNEUMONIAE | ALPHA-BETA-ALPHA SANDWICH, FLAVOPROTEIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
2gk4:B (THR164) to (SER229) THE CRYSTAL STRUCTURE OF THE DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN FROM STREPTOCOCCUS PNEUMONIAE | ALPHA-BETA-ALPHA SANDWICH, FLAVOPROTEIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
3ibj:A (GLY464) to (TYR573) X-RAY STRUCTURE OF PDE2A | PHOSPHODIESTERASE, PDE2A, GAF-DOMAINS, ALLOSTERIC REGULATION, CGMP, HYDROLASE, MEMBRANE
3ibj:B (GLY464) to (TYR573) X-RAY STRUCTURE OF PDE2A | PHOSPHODIESTERASE, PDE2A, GAF-DOMAINS, ALLOSTERIC REGULATION, CGMP, HYDROLASE, MEMBRANE
2vzw:A (GLY117) to (ARG202) X-RAY STRUCTURE OF THE HEME-BOUND GAF DOMAIN OF SENSORY HISTIDINE KINASE DOST OF MYCOBACTERIUM TUBERCULOSIS | TRANSFERASE, TRANSFERASE, OXYGEN BINDING, SIGNAL TRANSDUCTION
2vzw:B (GLY117) to (ALA201) X-RAY STRUCTURE OF THE HEME-BOUND GAF DOMAIN OF SENSORY HISTIDINE KINASE DOST OF MYCOBACTERIUM TUBERCULOSIS | TRANSFERASE, TRANSFERASE, OXYGEN BINDING, SIGNAL TRANSDUCTION
2w3d:A (GLY119) to (LEU205) STRUCTURE OF THE FIRST GAF DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | REDOX SENSOR, KINASE, HYPOXIA DOMAIN, TRANSFERASE
2w3d:B (GLY119) to (TYR206) STRUCTURE OF THE FIRST GAF DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | REDOX SENSOR, KINASE, HYPOXIA DOMAIN, TRANSFERASE
2w3e:A (VAL120) to (ALA203) OXIDIZED STRUCTURE OF THE FIRST GAF DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | REDOX SENSOR, MYCOBACTERIUM TUBERCULOSIS, HEME, KINASE, HYPOXIA, GAF DOMAIN, TRANSFERASE
2w3e:B (GLY119) to (GLN207) OXIDIZED STRUCTURE OF THE FIRST GAF DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | REDOX SENSOR, MYCOBACTERIUM TUBERCULOSIS, HEME, KINASE, HYPOXIA, GAF DOMAIN, TRANSFERASE
2w3f:A (GLY119) to (ALA203) REDUCED STRUCTURE OF THE FIRST GAF DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | REDOX SENSOR, MYCOBACTERIUM TUBERCULOSIS, HEME, KINASE, HYPOXIA, GAF DOMAIN, TRANSFERASE
2w3f:B (GLY119) to (LEU192) REDUCED STRUCTURE OF THE FIRST GAF DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | REDOX SENSOR, MYCOBACTERIUM TUBERCULOSIS, HEME, KINASE, HYPOXIA, GAF DOMAIN, TRANSFERASE
2w3g:A (GLY119) to (GLN207) AIR-OXIDIZED STRUCTURE OF THE FIRST GAF DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | REDOX SENSOR, MYCOBACTERIUM TUBERCULOSIS, HEME, KINASE, HYPOXIA, GAF DOMAIN, TRANSFERASE
2w3g:B (GLY119) to (GLN207) AIR-OXIDIZED STRUCTURE OF THE FIRST GAF DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | REDOX SENSOR, MYCOBACTERIUM TUBERCULOSIS, HEME, KINASE, HYPOXIA, GAF DOMAIN, TRANSFERASE
2w3h:A (GLY119) to (ARG204) CYANIDE BOUND STRUCTURE OF THE FIRST GAF DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | REDOX SENSOR, MYCOBACTERIUM TUBERCULOSIS, HEME, KINASE, HYPOXIA, GAF DOMAIN, TRANSFERASE
2w3h:B (GLY119) to (ARG204) CYANIDE BOUND STRUCTURE OF THE FIRST GAF DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | REDOX SENSOR, MYCOBACTERIUM TUBERCULOSIS, HEME, KINASE, HYPOXIA, GAF DOMAIN, TRANSFERASE
1td2:A (VAL161) to (GLY237) CRYSTAL STRUCTURE OF THE PDXY PROTEIN FROM ESCHERICHIA COLI | PYRIDOXAL KINASE, RIBOKINASE FAMILY, KINASE, PHOSPHORYLATION, PDXY, TRANSFERASE
1td2:B (ASN160) to (GLY237) CRYSTAL STRUCTURE OF THE PDXY PROTEIN FROM ESCHERICHIA COLI | PYRIDOXAL KINASE, RIBOKINASE FAMILY, KINASE, PHOSPHORYLATION, PDXY, TRANSFERASE
3imd:A (PRO66) to (ARG136) CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A FLEXIBLE AC-PY-Q-N-NH2 TRIPEPTIDE MIMIC | LIGAND PREORGANIZATION, PEPTIDE MIMICS, GOLGI APPARATUS, HOST-VIRUS INTERACTION, PHOSPHOPROTEIN, SH2 DOMAIN, SIGNALING PROTEIN, SIGNALING PROTEIN-PSEUDOPEPTIDE LIGAND COMPLEX, SIGNALING PROTEIN- PEPTIDE COMPLEX
3imd:B (PRO66) to (ARG136) CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A FLEXIBLE AC-PY-Q-N-NH2 TRIPEPTIDE MIMIC | LIGAND PREORGANIZATION, PEPTIDE MIMICS, GOLGI APPARATUS, HOST-VIRUS INTERACTION, PHOSPHOPROTEIN, SH2 DOMAIN, SIGNALING PROTEIN, SIGNALING PROTEIN-PSEUDOPEPTIDE LIGAND COMPLEX, SIGNALING PROTEIN- PEPTIDE COMPLEX
3in1:A (THR208) to (GLY273) CRYSTAL STRUCTURE OF A PUTATIVE RIBOKINASE IN COMPLEX WITH ADP FROM E.COLI | RIBOKINASE, TRANSFERASE, PFKB FAMILY, SUGAR KINASE YDJH, ADP NYSGXRC, 11206A,PSI2, KINASE, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3in7:A (PRO66) to (ARG136) CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A CYCLOPROPYL-CONSTRAINED AC-PY-Q-N-NH2 TRIPEPTIDE MIMIC | LIGAND PREORGANIZATION, PEPTIDE MIMICS, GOLGI APPARATUS, HOST-VIRUS INTERACTION, PHOSPHOPROTEIN, SH2 DOMAIN, SH3 DOMAIN, SIGNALING PROTEIN-PSEUDOPEPTIDE LIGAND COMPLEX, SIGNALING PROTEIN-PEPTIDE COMPLEX
3in8:A (PRO66) to (ARG136) CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A FLEXIBLE AC-PTYR-ILE-ASN-NH2 TRIPEPTIDE MIMIC | LIGAND PREORGANIZATION, GOLGI APPARATUS, PEPTIDE MIMICS, HOST-VIRUS INTERACTION, PHOSPHOPROTEIN, SH2 DOMAIN, SH3, SIGNALING PROTEIN, SIGNALING PROTEIN-PSEUDOPEPTIDE LIGAND COMPLEX,SIGNALING PROTEIN- PEPTIDE COMPLEX, SIGNALING PROTEIN-PEPTIDE COMPLEX
2gw6:B (ASP322) to (GLN396) NMR STRUCTURE OF THE HUMAN TRNA ENDONUCLEASE SEN15 SUBUNIT | SEN15_HUMAN, TRNA ENDONUCLEASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS, CESG, PROTEIN BINDING
4len:B (SER220) to (LEU290) CTX-M-9 IN COMPLEX WITH THE BROAD SPECTRUM INHIBITOR 3-(2- CARBOXYVINYL)BENZO(B)THIOPHENE-2-BORONIC ACID | BINDING SITES, STRUCTURE BASE DRUG DESIGN, DRUG DISCOVERY, MOLECULAR, ENZYME INHIBITORS, BETA LACTAMASES, BORONIC ACIDS, BROAD SPECTRUM, BACTERIAL RESISTANCE, DOUBLE PERTURBATION CYCLE ANALYSIS, THERMODYNAMICS, STRUCTURE ACTIVITY RELATIONSHIP, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2h5s:A (ALA217) to (HIS289) SA2-13 PENAM SULFONE COMPLEXED TO WT SHV-1 BETA-LACTAMASE | BETA-LACTAMASE INHIBITOR, DRUG DESIGN, HYDROLASE
3vrr:A (THR243) to (GLY305) CRYSTAL STRUCTURE OF THE TYROSINE KINASE BINDING DOMAIN OF CBL-C (PL MUTANT) IN COMPLEX WITH PHOSPHO-EGFR PEPTIDE | PTB DOMAIN, TKB (TYROSINE KINASE BINDING) DOMAIN, FOUR-HELIX BUNDLE (4H), CALCIUM-BINDING EF HAND, DIVERGENT SH2 DOMAIN, REGULATOR OF EGFR MEDIATED SIGNAL TRANSDUCTION, UBIQUITOUSLY EXPRESSED, PROTEIN BINDING-TRANSFERASE COMPLEX
4lry:D (CYS116) to (MET212) CRYSTAL STRUCTURE OF THE E.COLI DHAR(N)-DHAK(T79L) COMPLEX | COILED-COIL, HELIX ROTATION, GAF, PAS, TRANSCRIPTIONAL REGULATION COMPLEX, TRANSFERASE-TRANSCRIPTION REGULATOR COMPLEX
1u7w:B (ASN333) to (ARG405) PHOSPHOPANTOTHENOYLCYSTEINE SYNTHETASE FROM E. COLI, CTP- COMPLEX | COENZYME A BIOSYNTHESIS, LIGASE
1u7w:C (GLU335) to (ASN404) PHOSPHOPANTOTHENOYLCYSTEINE SYNTHETASE FROM E. COLI, CTP- COMPLEX | COENZYME A BIOSYNTHESIS, LIGASE
1u7z:A (GLU335) to (ARG405) PHOSPHOPANTOTHENOYLCYSTEINE SYNTHETASE FROM E. COLI, 4'- PHOSPHOPANTOTHENOYL-CMP COMPLEX | COENZYME A BIOSYNTHESIS, LIGASE
1u7z:B (GLU335) to (ARG405) PHOSPHOPANTOTHENOYLCYSTEINE SYNTHETASE FROM E. COLI, 4'- PHOSPHOPANTOTHENOYL-CMP COMPLEX | COENZYME A BIOSYNTHESIS, LIGASE
1u7z:C (VAL334) to (ASN404) PHOSPHOPANTOTHENOYLCYSTEINE SYNTHETASE FROM E. COLI, 4'- PHOSPHOPANTOTHENOYL-CMP COMPLEX | COENZYME A BIOSYNTHESIS, LIGASE
1u80:A (VAL334) to (ARG405) PHOSPHOPANTOTHENOYLCYSTEINE SYNTHETASE FROM E. COLI, CMP COMPLEX | COENZYME A BIOSYNTHESIS, LIGASE
1u80:B (VAL334) to (ARG405) PHOSPHOPANTOTHENOYLCYSTEINE SYNTHETASE FROM E. COLI, CMP COMPLEX | COENZYME A BIOSYNTHESIS, LIGASE
1u80:C (VAL334) to (ARG405) PHOSPHOPANTOTHENOYLCYSTEINE SYNTHETASE FROM E. COLI, CMP COMPLEX | COENZYME A BIOSYNTHESIS, LIGASE
1uc4:E (ASP112) to (ARG178) STRUCTURE OF DIOL DEHYDRATASE COMPLEXED WITH (S)-1,2- PROPANEDIOL | ALPHA/BETA BARREL, LYASE
1uc5:E (ASP112) to (LYS177) STRUCTURE OF DIOL DEHYDRATASE COMPLEXED WITH (R)-1,2- PROPANEDIOL | ALPHA/BETA BARREL, LYASE
1iou:A (GLY29) to (ALA104) SOLUTION STRUCTURE OF YKT6P (1-140) | SNARE, MEMBRANE PROTEIN
3wb2:B (PRO82) to (GLY155) HCGB FROM METHANOCALDOCOCCUS JANNASCHII IN COMPLEX WITH THE GUANYLYL- PYRIDINOL PRODUCT IN A MODEL REACTION OF [FE]-HYDROGENASE COFACTOR BIOSYNTHESIS | GTP-BINDING DOMAIN, GUANYLYLTRANSFERASE, TRANSFERASE
3wb2:C (PRO82) to (GLY155) HCGB FROM METHANOCALDOCOCCUS JANNASCHII IN COMPLEX WITH THE GUANYLYL- PYRIDINOL PRODUCT IN A MODEL REACTION OF [FE]-HYDROGENASE COFACTOR BIOSYNTHESIS | GTP-BINDING DOMAIN, GUANYLYLTRANSFERASE, TRANSFERASE
3wb2:D (PRO82) to (GLY155) HCGB FROM METHANOCALDOCOCCUS JANNASCHII IN COMPLEX WITH THE GUANYLYL- PYRIDINOL PRODUCT IN A MODEL REACTION OF [FE]-HYDROGENASE COFACTOR BIOSYNTHESIS | GTP-BINDING DOMAIN, GUANYLYLTRANSFERASE, TRANSFERASE
4mbh:A (ALA217) to (HIS289) PENAM SULFONE PSR-3-226 BOUND TO E166A VARIANT OF SHV-1 BETA-LACTAMASE | CLASS A BETA-LACTAMASE, HYDROLASE
1uus:A (ARG594) to (HIS658) STRUCTURE OF AN ACTIVATED DICTYOSTELIUM STAT IN ITS DNA-UNBOUND FORM | DICTYOSTELIUM, STAT, SH2, SIGNAL TRANSDUCTION, TRANSDUCER, TRANSCRIPTION FACTOR
4me4:A (GLY71) to (ALA178) METALLO-ENZYME FROM P. MARINA | STRUCTURAL GENOMICS, OXFORD PROTEIN PRODUCTION FACILITY, OPPF, PHOSPHOHYDROLASE, HYDROLASE
4me4:B (GLY71) to (ALA178) METALLO-ENZYME FROM P. MARINA | STRUCTURAL GENOMICS, OXFORD PROTEIN PRODUCTION FACILITY, OPPF, PHOSPHOHYDROLASE, HYDROLASE
1iwb:B (ASP112) to (ARG178) CRYSTAL STRUCTURE OF DIOL DEHYDRATASE | BETA-ALPHA-BARRELS, LYASE
1iwb:E (VAL113) to (ARG178) CRYSTAL STRUCTURE OF DIOL DEHYDRATASE | BETA-ALPHA-BARRELS, LYASE
1iyo:A (SER220) to (PHE290) TOHO-1 BETA-LACTAMASE IN COMPLEX WITH CEFOTAXIME | EXTENDED-SPECTRUM, ESBL, BETA-LACTAMASE, ACYL-ENZYME, CEFOTAXIME, COMPLEX, HYDROLASE
1iyp:A (GLY217) to (PHE290) TOHO-1 BETA-LACTAMASE IN COMPLEX WITH CEPHALOTHIN | BETA-LACTAMASE, ACYL-ENZYME, COMPLEX, CEPHALOTHIN, HYDROLASE
4mmn:A (GLY58) to (ALA132) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF TYPE II FREE METHIONINE-R- SULFOXIDE REDUCTASE FROM THERMOPLASMA ACIDOPHILUM | REDUCTASE, OXIDOREDUCTASE
4mmn:B (LEU59) to (ALA132) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF TYPE II FREE METHIONINE-R- SULFOXIDE REDUCTASE FROM THERMOPLASMA ACIDOPHILUM | REDUCTASE, OXIDOREDUCTASE
4mmn:C (LEU59) to (LEU130) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF TYPE II FREE METHIONINE-R- SULFOXIDE REDUCTASE FROM THERMOPLASMA ACIDOPHILUM | REDUCTASE, OXIDOREDUCTASE
4mmn:D (GLY58) to (MET131) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF TYPE II FREE METHIONINE-R- SULFOXIDE REDUCTASE FROM THERMOPLASMA ACIDOPHILUM | REDUCTASE, OXIDOREDUCTASE
4mmn:E (GLY58) to (MET131) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF TYPE II FREE METHIONINE-R- SULFOXIDE REDUCTASE FROM THERMOPLASMA ACIDOPHILUM | REDUCTASE, OXIDOREDUCTASE
4mmn:F (GLY58) to (MET131) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF TYPE II FREE METHIONINE-R- SULFOXIDE REDUCTASE FROM THERMOPLASMA ACIDOPHILUM | REDUCTASE, OXIDOREDUCTASE
4mmn:G (LEU59) to (LEU130) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF TYPE II FREE METHIONINE-R- SULFOXIDE REDUCTASE FROM THERMOPLASMA ACIDOPHILUM | REDUCTASE, OXIDOREDUCTASE
4mmn:H (LEU59) to (MET131) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF TYPE II FREE METHIONINE-R- SULFOXIDE REDUCTASE FROM THERMOPLASMA ACIDOPHILUM | REDUCTASE, OXIDOREDUCTASE
4mn7:A (GLY58) to (MET131) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF TYPE II FREE METHIONINE-R- SULFOXIDE REDUCTASE FROM THERMOPLASMA ACIDOPHILUM | REDUCTASE, OXIDOREDUCTASE
4mn7:B (GLY58) to (LEU130) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF TYPE II FREE METHIONINE-R- SULFOXIDE REDUCTASE FROM THERMOPLASMA ACIDOPHILUM | REDUCTASE, OXIDOREDUCTASE
5aoy:A (ASN166) to (CYS228) STRUCTURE OF MOUSE ENDONUCLEASE V | HYDROLASE, ENDONUCLEASE, ENDONUCLEASE V
1vet:A (ARG46) to (LEU110) CRYSTAL STRUCTURE OF P14/MP1 AT 1.9 A RESOLUTION | PROFILIN, SCAFFOLD, ADAPTOR, SIGNALING PROTEIN/PROTEIN BINDING COMPLEX
1veu:A (ARG46) to (VAL120) CRYSTAL STRUCTURE OF THE P14/MP1 COMPLEX AT 2.15 A RESOLUTION | PROFILIN, SCAFFOLD, ADAPTOR, SIGNALING PROTEIN/PROTEIN BINDING COMPLEX
5aq7:A (LEU350) to (TRP418) DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY | CHAPERONE, CRYSTALLIZATION CHAPERONE, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), RIGID DOMAIN FUSION
5aq7:B (LEU350) to (TRP418) DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY | CHAPERONE, CRYSTALLIZATION CHAPERONE, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), RIGID DOMAIN FUSION
5aq8:A (LEU358) to (TRP426) DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY | CHAPERONE, CRYSTALLIZATION CHAPERONE, DESIGNED ANKYRIN REPEAT PROTEIN ( DARPIN), RIGID DOMAIN FUSION
5aqa:A (LEU350) to (MET414) DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY | CHAPERONE, CRYSTALLIZATION CHAPERONE, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), RIGID DOMAIN FUSION
5aqa:B (LEU350) to (TRP418) DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY | CHAPERONE, CRYSTALLIZATION CHAPERONE, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), RIGID DOMAIN FUSION
1vi9:A (VAL161) to (GLY237) CRYSTAL STRUCTURE OF PYRIDOXAMINE KINASE | STRUCTURAL GENOMICS, TRANSFERASE
1vi9:B (VAL161) to (GLY237) CRYSTAL STRUCTURE OF PYRIDOXAMINE KINASE | STRUCTURAL GENOMICS, TRANSFERASE
3wva:A (GLU83) to (PHE167) SEMET-LABELLED HCGF FROM METHANOCALDOCOCCUS JANNASCHII | THIOESTERASE, HYDROLASE
3wva:B (SER82) to (PHE167) SEMET-LABELLED HCGF FROM METHANOCALDOCOCCUS JANNASCHII | THIOESTERASE, HYDROLASE
3wvb:A (GLU83) to (LYS164) HCGF FROM METHANOCALDOCOCCUS JANNASCHII | THIOESTERASE, HYDROLASE
3wvb:B (SER82) to (PHE167) HCGF FROM METHANOCALDOCOCCUS JANNASCHII | THIOESTERASE, HYDROLASE
3wvc:A (GLU83) to (LYS164) GUANYLYLPYRIDINOL (GP)-BOUND HCGF FROM METHANOCALDOCOCCUS JANNASCHII | THIOESTERASE, HYDROLASE
3wvc:B (GLU83) to (PHE167) GUANYLYLPYRIDINOL (GP)-BOUND HCGF FROM METHANOCALDOCOCCUS JANNASCHII | THIOESTERASE, HYDROLASE
1jwo:A (SER128) to (ASP199) CRYSTAL STRUCTURE ANALYSIS OF THE SH2 DOMAIN OF THE CSK HOMOLOGOUS KINASE CHK | ANTIPARALLEL BETA SHEET, TRANSFERASE
4n1h:A (LEU220) to (ASN291) STRUCTURE OF A SINGLE-DOMAIN CAMELID ANTIBODY FRAGMENT CAB-F11N IN COMPLEX WITH THE BLAP BETA-LACTAMASE FROM BACILLUS LICHENIFORMIS | IMMUNOGLOBULIN FOLD, ANTIGEN BINDING, HYDROLASE-IMMUNE SYSTEM COMPLEX
3jab:B (GLY464) to (ASN568) DOMAIN ORGANIZATION AND CONFORMATIONAL PLASTICITY OF THE G PROTEIN EFFECTOR, PDE6 | PHOSPHODIESTERASE, PHOTORECEPTOR, HYDROLASE-IMMUNE SYSTEM COMPLEX
3jab:N (GLY464) to (ASN568) DOMAIN ORGANIZATION AND CONFORMATIONAL PLASTICITY OF THE G PROTEIN EFFECTOR, PDE6 | PHOSPHODIESTERASE, PHOTORECEPTOR, HYDROLASE-IMMUNE SYSTEM COMPLEX
2xss:A (MET410) to (PHE495) CRYSTAL STRUCTURE OF GAFB FROM THE HUMAN PHOSPHODIESTERASE 5 | HYDROLASE
2xss:B (TYR411) to (PHE495) CRYSTAL STRUCTURE OF GAFB FROM THE HUMAN PHOSPHODIESTERASE 5 | HYDROLASE
2jkr:M (ALA28) to (TYR92) AP2 CLATHRIN ADAPTOR CORE WITH DILEUCINE PEPTIDE RM( PHOSPHOS)QIKRLLSE | ALTERNATIVE SPLICING, PHOSPHOPROTEIN, PHOSPHORYLATION, PROTEIN TRANSPORT, ADAPTOR, MEMBRANE, TRANSPORT, COATED PIT, ENDOCYTOSIS, CELL MEMBRANE, LIPID-BINDING
2jkr:U (ALA28) to (TYR92) AP2 CLATHRIN ADAPTOR CORE WITH DILEUCINE PEPTIDE RM( PHOSPHOS)QIKRLLSE | ALTERNATIVE SPLICING, PHOSPHOPROTEIN, PHOSPHORYLATION, PROTEIN TRANSPORT, ADAPTOR, MEMBRANE, TRANSPORT, COATED PIT, ENDOCYTOSIS, CELL MEMBRANE, LIPID-BINDING
2y1m:E (TYR274) to (GLY335) STRUCTURE OF NATIVE C-CBL | LIGASE, UBIQUITIN RING E3 LIGASE
2k79:B (SER245) to (GLN323) SOLUTION STRUCTURE OF THE BINARY COMPLEX BETWEEN THE SH3 AND SH2 DOMAIN OF INTERLEUKIN-2 TYROSINE KINASE | SH3, SH2, NOVEL, CIS, ATP-BINDING, CELL MEMBRANE, KINASE, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SH2 DOMAIN, SH3 DOMAIN, TRANSFERASE, TYROSINE-PROTEIN KINASE, ZINC, ZINC-FINGER
2kc9:A (THR21) to (ILE94) STRUCTURE OF E. COLI TOXIN RELE (R81A/R83A) MUTANT IN THE FREE STATE | RELE, TOXIN, REPRESSOR, STRESS RESPONSE, TRANSCRIPTION, TRANSCRIPTION REGULATION
2y3a:B (ASN622) to (SER694) CRYSTAL STRUCTURE OF P110BETA IN COMPLEX WITH ICSH2 OF P85BETA AND THE DRUG GDC-0941 | TRANSFERASE, PHOSPHOINOSITIDE 3-KINASE, RTK
2y79:A (GLY119) to (GLN207) STRUCTURE OF THE FIRST GAF DOMAIN E87A MUTANT OF MYCOBACTERIUM TUBERCULOSIS DOSS | TRANSFERASE
2y79:B (GLY119) to (GLN207) STRUCTURE OF THE FIRST GAF DOMAIN E87A MUTANT OF MYCOBACTERIUM TUBERCULOSIS DOSS | TRANSFERASE
1kgf:A (LEU220) to (PHE290) STRUCTURE OF BETA-LACTAMASE ASN 170 GLN MUTANT | HYDROLASE, ANTIBIOTIC RESISTANCE, SIGNAL, PLASMID, TRANSPOSABLE ELEMENT
1kgg:A (LEU220) to (LYS288) STRUCTURE OF BETA-LACTAMASE GLU166GLN:ASN170ASP MUTANT | HYDROLASE, ANTIBIOTIC RESISTANCE, BETA-LACTAM HYDROLYSIS
2y8h:A (GLY119) to (ALA203) STRUCTURE OF THE FIRST GAF DOMAIN E87G MUTANT OF MYCOBACTERIUM TUBERCULOSIS DOSS | TRANSFERASE
2y8h:B (GLY119) to (LEU205) STRUCTURE OF THE FIRST GAF DOMAIN E87G MUTANT OF MYCOBACTERIUM TUBERCULOSIS DOSS | TRANSFERASE
2lct:A (ARG678) to (ASN748) SOLUTION STRUCTURE OF THE VAV1 SH2 DOMAIN COMPLEXED WITH A SYK-DERIVED DOUBLY PHOSPHORYLATED PEPTIDE | PHOSPHOPEPTIDE, SYK KINASE, TYROSINE KINASE, PROTEIN-PEPTIDE COMPLEX, PHOSPHORYLATED PEPTIDE, PHOSPHOTYROSINE BINDING DOMAIN, B CELL SIGNALING PROTEIN, SIGNALING PROTEIN
2nut:C (ASP29) to (GLN98) CRYSTAL STRUCTURE OF THE HUMAN SEC23A/24A HETERODIMER, COMPLEXED WITH THE SNARE PROTEIN SEC22B | HUMAN COPII SEC23/24 COMPLEXED WITH SEC22, PROTEIN TRANSPORT
5ced:A (THR306) to (GLY414) PENICILLIN G ACYLATED BD3459 PREDATORY ENDOPEPTIDASE FROM BDELLOVIBRIO BACTERIOVORUS IN COMPLEX WITH IMMUNITY PROTEIN BD3460 | TRANSPEPTIDASE AND ANKYRIN REPEAT, HYDROLAE, PROTEIN BINDING, HYDROLASE
5cer:A (THR294) to (SER402) BD0816 PREDATORY ENDOPEPTIDASE FROM BDELLOVIBRIO BACTERIOVORUS IN COMPLEX WITH IMMUNITY PROTEIN BD3460 | TRANSPEPTIDASE AND ANKYRIN REPEAT, IMMUNE SYSTEM
5cer:E (THR294) to (SER402) BD0816 PREDATORY ENDOPEPTIDASE FROM BDELLOVIBRIO BACTERIOVORUS IN COMPLEX WITH IMMUNITY PROTEIN BD3460 | TRANSPEPTIDASE AND ANKYRIN REPEAT, IMMUNE SYSTEM
2o0m:A (SER256) to (ILE300) THE CRYSTAL STRUCTURE OF THE PUTATIVE SORC FAMILY TRANSCRIPTIONAL REGULATOR FROM ENTEROCOCCUS FAECALIS | SORC FAMILY, TRANSCRIPTIONAL REGULATOR, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, TRANSCRIPTION
4a4c:A (THR273) to (GLY335) STRUCTURE OF PHOSPHOTYR371-C-CBL-UBCH5B-ZAP-70 COMPLEX | LIGASE-TRANSFERASE COMPLEX
1lum:A (ASP19) to (TYR96) NMR STRUCTURE OF THE ITK SH2 DOMAIN, PRO287TRANS, 20 LOW ENERGY STRUCTURES | CIS/TRANS ISOMERIZATION, INTERLEUKIN-2 TYROSINE KINASE, ITK, T-CELL SPECIFIC KINASE, TSK, SRC HOMOLOGY 2, SH2, PROLINE, TRANSFERASE
5cs4:B (PRO1095) to (GLU1195) CRYSTAL STRUCTURE OF DOMAINS AC3-AC5 OF YEAST ACETYL-COA CARBOXYLASE | ACETYL-COA CARBOXYLASE, LIGASE
5csa:B (ASP1094) to (ILE1197) CRYSTAL STRUCTURE OF DOMAINS BT-BCCP-AC1-AC5 OF YEAST ACETYL-COA CARBOXYLASE | ACETYL-COA CARBOXYLASE, LIGASE
5csk:A (TYR1507) to (GLY1615) CRYSTAL STRUCTURE OF YEAST ACETYL-COA CARBOXYLASE, UNBIOTINYLATED | ACETYL-COA CARBOXYLASE, LIGASE
2zd8:A (ASP214) to (HIS289) SHV-1 CLASS A BETA-LACTAMASE COMPLEXED WITH MEROPENEM | HYDROLASE, INHIBITOR, BETA-LACTAM ANTIBIOTICS, ANTIBIOTIC RESISTANCE
5csl:B (PRO1095) to (VAL1196) CRYSTAL STRUCTURE OF THE 500 KD YEAST ACETYL-COA CARBOXYLASE HOLOENZYME DIMER | ACETYL-COA CARBOXYLASE, LIGASE
2zl1:A (ARG46) to (VAL120) MP1-P14 SCAFFOLDING COMPLEX | SCAFFOLD, COMPLEX, ALPHA/BETA, ENDOSOME, MEMBRANE, LYSOSOME, PROTEIN BINDING
2zl1:B (ASP41) to (GLU116) MP1-P14 SCAFFOLDING COMPLEX | SCAFFOLD, COMPLEX, ALPHA/BETA, ENDOSOME, MEMBRANE, LYSOSOME, PROTEIN BINDING
2zmf:A (GLY329) to (ARG422) CRYSTAL STRUCTURE OF THE C-TERMINAL GAF DOMAIN OF HUMAN PHOSPHODIESTERASE 10A | GAF DOMAIN, PHOSPHODIESTERASE, CAMP, CGMP, CGMP-BINDING, HYDROLASE, NUCLEOTIDE-BINDING, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2zmf:B (GLY329) to (HIS419) CRYSTAL STRUCTURE OF THE C-TERMINAL GAF DOMAIN OF HUMAN PHOSPHODIESTERASE 10A | GAF DOMAIN, PHOSPHODIESTERASE, CAMP, CGMP, CGMP-BINDING, HYDROLASE, NUCLEOTIDE-BINDING, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2zmv:A (SER105) to (ASN184) CRYSTAL STRUCTURE OF SYNBINDIN | LONGIN DOMAIN, SYNBINDIN, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, GOLGI APPARATUS, TRANSPORT, TRANSPORT PROTEIN
3ko6:A (GLY99) to (SER176) CRYSTAL STRUCTURE OF YEAST FREE METHIONINE-R-SULFOXIDE REDUCTASE YKG9 IN COMPLEX WITH THE SUBSTRATE | SACCHAROMYCES CEREVISIAE, METHIONINE-R-SULFOXIDE REDUCTASE, SUBSTRATE BINDING, CATALYTIC MECHANISM, PRODUCT DISSOCIATION, OXIDOREDUCTASE
3ko6:B (GLY99) to (LYS175) CRYSTAL STRUCTURE OF YEAST FREE METHIONINE-R-SULFOXIDE REDUCTASE YKG9 IN COMPLEX WITH THE SUBSTRATE | SACCHAROMYCES CEREVISIAE, METHIONINE-R-SULFOXIDE REDUCTASE, SUBSTRATE BINDING, CATALYTIC MECHANISM, PRODUCT DISSOCIATION, OXIDOREDUCTASE
4p9v:A (PRO66) to (ARG136) GRB2 SH2 COMPLEXED WITH A PTYR-AC6CN-ASN TRIPEPTIDE | GRB2 SH2, CATION-PI INTERACTION, SIGNALING PROTEIN-ANTAGONIST COMPLEX
4p9z:A (PRO66) to (ARG136) GRB2 SH2 COMPLEXED WITH A PTYR-AC6C-ASN TRIPEPTIDE | GRB2 SH2, CATION-PI INTERACTION
3ksf:A (VAL77) to (LEU153) STRUCTURE OF FRMSR OF STAPHYLOCOCCUS AUREUS (REDUCED FORM) | FRMSR, FREE-MET-R-SO, OXIDOREDUCTASE
3ksf:B (GLY76) to (ALA154) STRUCTURE OF FRMSR OF STAPHYLOCOCCUS AUREUS (REDUCED FORM) | FRMSR, FREE-MET-R-SO, OXIDOREDUCTASE
3ksf:C (VAL77) to (ALA154) STRUCTURE OF FRMSR OF STAPHYLOCOCCUS AUREUS (REDUCED FORM) | FRMSR, FREE-MET-R-SO, OXIDOREDUCTASE
3ksf:D (VAL77) to (ALA154) STRUCTURE OF FRMSR OF STAPHYLOCOCCUS AUREUS (REDUCED FORM) | FRMSR, FREE-MET-R-SO, OXIDOREDUCTASE
3ksf:E (VAL77) to (ALA154) STRUCTURE OF FRMSR OF STAPHYLOCOCCUS AUREUS (REDUCED FORM) | FRMSR, FREE-MET-R-SO, OXIDOREDUCTASE
3ksf:F (GLY76) to (ALA154) STRUCTURE OF FRMSR OF STAPHYLOCOCCUS AUREUS (REDUCED FORM) | FRMSR, FREE-MET-R-SO, OXIDOREDUCTASE
3ksf:G (GLY76) to (ALA154) STRUCTURE OF FRMSR OF STAPHYLOCOCCUS AUREUS (REDUCED FORM) | FRMSR, FREE-MET-R-SO, OXIDOREDUCTASE
3ksf:H (GLY76) to (ALA154) STRUCTURE OF FRMSR OF STAPHYLOCOCCUS AUREUS (REDUCED FORM) | FRMSR, FREE-MET-R-SO, OXIDOREDUCTASE
3ksg:A (VAL77) to (ALA154) STRUCTURE OF FRMSR OF STAPHYLOCOCCUS AUREUS (COMPLEX WITH SUBSTRATE) | FRMSR, FREE-MET-R-SO, OXIDOREDUCTASE
3ksg:B (VAL77) to (ALA154) STRUCTURE OF FRMSR OF STAPHYLOCOCCUS AUREUS (COMPLEX WITH SUBSTRATE) | FRMSR, FREE-MET-R-SO, OXIDOREDUCTASE
3ksh:A (VAL77) to (LEU153) STRUCTURE OF FRMSR OF STAPHYLOCOCCUS AUREUS (OXIDIZED FORM) | FRMSR, FREE-MET-R-SO, OXIDOREDUCTASE
3ksi:A (GLY76) to (LEU153) STRUCTURE OF FRMSR OF STAPHYLOCOCCUS AUREUS (COMPLEX WITH 2-PROPANOL) | FRMSR, FREE-MET-R-SO, OXIDOREDUCTASE
3a8j:C (ASP161) to (GLY214) CRYSTAL STRUCTURE OF ET-EHRED COMPLEX | GLYCINE CLEAVAGE SYSTEM, AMINOTRANSFERASE, TRANSFERASE, LIPOYL, TRANSFERASE-TRANSPORT PROTEIN COMPLEX
3a8j:D (ASP161) to (GLY214) CRYSTAL STRUCTURE OF ET-EHRED COMPLEX | GLYCINE CLEAVAGE SYSTEM, AMINOTRANSFERASE, TRANSFERASE, LIPOYL, TRANSFERASE-TRANSPORT PROTEIN COMPLEX
3a8k:B (ASP161) to (GLY214) CRYSTAL STRUCTURE OF ETD97N-EHRED COMPLEX | GLYCINE CLEAVAGE SYSTEM, AMINOTRANSFERASE, TRANSFERASE, LIPOYL, TRANSFERASE-TRANSPORT PROTEIN COMPLEX
3a8k:C (ASN160) to (GLY214) CRYSTAL STRUCTURE OF ETD97N-EHRED COMPLEX | GLYCINE CLEAVAGE SYSTEM, AMINOTRANSFERASE, TRANSFERASE, LIPOYL, TRANSFERASE-TRANSPORT PROTEIN COMPLEX
3a8k:D (ASP161) to (GLY214) CRYSTAL STRUCTURE OF ETD97N-EHRED COMPLEX | GLYCINE CLEAVAGE SYSTEM, AMINOTRANSFERASE, TRANSFERASE, LIPOYL, TRANSFERASE-TRANSPORT PROTEIN COMPLEX
1yly:A (GLY217) to (LEU290) X-RAY CRYSTALLOGRAPHIC STRUCTURE OF CTX-M-9 BETA-LACTAMASE COMPLEXED WITH CEFTAZIDIME-LIKE BORONIC ACID | CTX-M, BETA-LACTAMASE, TRANSITION STATE, CEFTAZIDIME, BORONIC ACID, HYDROLASE
1ylz:A (GLY217) to (LEU290) X-RAY CRYSTALLOGRAPHIC STRUCTURE OF CTX-M-14 BETA-LACTAMASE COMPLEXED WITH CEFTAZIDIME-LIKE BORONIC ACID | CTX-M, BETA-LACTAMASE, TRANSITION STATE, CEFTAZIDIME, BORONIC ACID, HYDROLASE
1ylz:B (GLY217) to (LEU290) X-RAY CRYSTALLOGRAPHIC STRUCTURE OF CTX-M-14 BETA-LACTAMASE COMPLEXED WITH CEFTAZIDIME-LIKE BORONIC ACID | CTX-M, BETA-LACTAMASE, TRANSITION STATE, CEFTAZIDIME, BORONIC ACID, HYDROLASE
1ym1:B (SER220) to (LEU290) X-RAY CRYSTALLOGRAPHIC STRUCTURE OF CTX-M-9 BETA-LACTAMASE COMPLEXED WITH A BORONIC ACID INHIBITOR (SM2) | CTX-M, BETA-LACTAMASE, TRANSITION STATE, DEACYLATION, BORONIC ACID, HYDROLASE
3abo:B (GLU210) to (GLU285) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND ETHANOLAMINE | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
3abo:D (GLU210) to (GLU285) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND ETHANOLAMINE | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
3abq:B (GLU210) to (LYS287) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND 2-AMINO-1-PROPANOL | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
3abq:D (GLU210) to (GLU285) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND 2-AMINO-1-PROPANOL | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
3abr:B (GLU210) to (GLU285) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL (SUBSTRATE-FREE FORM) | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
3abr:D (GLU210) to (GLN286) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL (SUBSTRATE-FREE FORM) | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
3abs:B (ARG206) to (LYS287) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH ADENINYLPENTYLCOBALAMIN AND ETHANOLAMINE | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
3abs:D (GLU210) to (LYS287) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH ADENINYLPENTYLCOBALAMIN AND ETHANOLAMINE | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
1yvh:A (THR273) to (GLY335) CRYSTAL STRUCTURE OF THE C-CBL TKB DOMAIN IN COMPLEX WITH THE APS PTYR-618 PHOSPHOPEPTIDE | X-RAY CRYSTALLOGRAPHY; PHOSPHOTYROSINE; ADAPTER PROTEIN, LIGASE,SIGNALING PROTEIN,IMMUNE SYSTEM
3leq:A (LEU46) to (ILE123) THE CRYSTAL STRUCTURE OF THE ROADBLOCK/LC7 DOMAIN FROM STREPTOMYCES AVERMITILLIS TO 1.85A | PSI, MCSG, STRUCTURAL GENOMICS, MIDWEST CENTER FOR STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, STRUCTURE GENOMICS, UNKNOWN FUNCTION
3lfv:A (MET410) to (ARG519) CRYSTAL STRUCTURE OF UNLIGANDED PDE5A GAF DOMAIN | GAF, CGMP SIGNALING, HYDROLASE
3lfv:B (ALA412) to (LYS518) CRYSTAL STRUCTURE OF UNLIGANDED PDE5A GAF DOMAIN | GAF, CGMP SIGNALING, HYDROLASE
3any:B (GLU210) to (LYS287) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND (R)-2-AMINO-1-PROPANOL | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN, TIM BARREL
3any:D (GLU210) to (GLU285) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND (R)-2-AMINO-1-PROPANOL | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN, TIM BARREL
4arz:B (MET227) to (TRP325) THE CRYSTAL STRUCTURE OF GTR1P-GTR2P COMPLEXED WITH GTP-GDP | HYDROLASE, GTPASE, CELL GROWTH
1zup:A (SER185) to (THR256) CRYSTAL STRUCTURE OF A PUTATIVE NUCLEASE WITH A RIBONUCLEASE H-LIKE MOTIF FOLD (TM1739) FROM THERMOTOGA MARITIMA AT 2.20 A RESOLUTION | PUTATIVE NUCLEASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI, HYDROLASE
1zup:B (LYS186) to (THR261) CRYSTAL STRUCTURE OF A PUTATIVE NUCLEASE WITH A RIBONUCLEASE H-LIKE MOTIF FOLD (TM1739) FROM THERMOTOGA MARITIMA AT 2.20 A RESOLUTION | PUTATIVE NUCLEASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI, HYDROLASE
3ly4:A (GLY217) to (ASN291) CRYSTAL STRUCTURE OF FLUOROPHORE-LABELED CLASS A -LACTAMASE PENP- E166CB IN COMPLEX WITH PENICILLIN G | BETA-LACTAMASE, FLUOROPHORE, BIOSENSOR, HYDROLASE, ANTIBIOTIC RESISTANCE, CELL MEMBRANE, LIPOPROTEIN, MEMBRANE, PALMITATE
2a49:A (ALA217) to (HIS289) CRYSTAL STRUCTURE OF CLAVULANIC ACID BOUND TO E166A VARIANT OF SHV-1 BETA-LACTAMASE | BETA-LACTAMASE, BETA-LACTAM HYDROLASE, PENICILLINASE, DETERGENT BINDING, INHIBITOR DESIGN, COVALENT INTERMEDIATE
5ee8:A (ALA217) to (HIS287) CRYSTAL STRUCTURE OF S02030 BORONIC ACID INHIBITOR COMPLEXED TO SHV-1 BETA-LACTAMASE | TRANSITION STATE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qji:A (ASP342) to (GLN412) CRYSTAL STRUCTURE OF THE C-TERMINAL CTP-BINDING DOMAIN OF A PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE/PHOSPHOPANTOTHENATE- CYSTEINE LIGASE WITH BOUND CTP FROM MYCOBACTERIUM SMEGMATIS | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, DNA / PANTOTHENATE METABOLISM FLAVOPROTEIN, CTP-BINDING, PANTOTHENATE METABLOSIM, LIGASE
4qji:B (ASP342) to (GLN412) CRYSTAL STRUCTURE OF THE C-TERMINAL CTP-BINDING DOMAIN OF A PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE/PHOSPHOPANTOTHENATE- CYSTEINE LIGASE WITH BOUND CTP FROM MYCOBACTERIUM SMEGMATIS | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, DNA / PANTOTHENATE METABOLISM FLAVOPROTEIN, CTP-BINDING, PANTOTHENATE METABLOSIM, LIGASE
5em1:A (PRO46) to (GLY132) CRYSTAL STRUCTURE OF RAGWEED ALLERGEN AMB A 8 | ALLERGEN
3bfc:D (GLY217) to (GLU288) CLASS A BETA-LACTAMASE SED-G238C COMPLEXED WITH IMIPENEM | HYDROLASE, BETA-LACTAMASE, CLASS A, SED-G238C, IMIPENEM, ACYL-ENZYME
3bfd:B (GLY217) to (GLU288) CRYSTAL STRUCTURE OF THE CLASS A BETA-LACTAMASE SED-G238C MUTANT FROM CITROBACTER SEDLAKII | HYDROLASE, BETA-LACTAMASE, CLASS A, SED-G238C MUTANT
3bfe:A (GLY217) to (GLU288) CRYSTAL STRUCTURE OF THE CLASS A BETA-LACTAMASE SED-1 FROM CITROBACTER SEDLAKII | HYDROLASE, BETA-LACTAMASE, CLASS A, SED-1
3bff:A (GLY217) to (GLU288) CLASS A BETA-LACTAMASE SED-G238C COMPLEXED WITH FAROPENEM | HYDROLASE, BETA-LACTAMASE, CLASS A SED-G238C, FAROPENEM, ACYL-ENZYME
3bff:D (GLY217) to (GLU288) CLASS A BETA-LACTAMASE SED-G238C COMPLEXED WITH FAROPENEM | HYDROLASE, BETA-LACTAMASE, CLASS A SED-G238C, FAROPENEM, ACYL-ENZYME
4qsy:A (THR12) to (HIS84) SHP2 SH2 DOMAIN IN COMPLEX WITH GAB1 PEPTIDE | SH2 DOMAIN, SIGNALLING, PTR BINDING, HYDROLASE-PROTEIN BINDING COMPLEX
3blm:A (LEU220) to (PHE290) REFINED CRYSTAL STRUCTURE OF BETA-LACTAMASE FROM STAPHYLOCOCCUS AUREUS PC1 AT 2.0 | HYDROLASE
5ey1:A (PRO72) to (LEU179) CRYSTAL STRUCTURE OF CODY FROM STAPHYLOCOCCUS AUREUS WITH GTP AND ILE | GTP SENSING, PLEIOTROPIC TRANSCRIPTION REGULATOR, TRANSCRIPTION
3mxr:A (ALA217) to (HIS289) SHV-1 BETA-LACTAMASE COMPLEX WITH COMPOUND 1 | BETA-LACTAMASE, BORONIC ACID TRANSITION STATE INHIBITOR, DRUG DESIGN, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3mxs:A (ALA217) to (HIS289) SHV-1 BETA-LACTAMASE COMPLEX WITH COMPOUND 2 | BETA-LACTAMASE, BORONIC ACID TRANSITION STATE INHIBITOR, DRUG DESIGN, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3bw6:A (SER34) to (ALA104) CRYSTAL STRUCTURE OF THE LONGIN DOMAIN OF YEAST YKT6 | YKT6P, FARNESYLATION, VACUOLE FUSION, SNARE, COILED COIL, LIPOPROTEIN, MEMBRANE, PHOSPHOPROTEIN, PRENYLATION, TRANSFERASE
5feg:A (GLU46) to (GLY130) CRYSTAL STRUCTURE OF THE DIMERIC ALLERGEN PROFILIN (HEV B 8) | ACTIN BINDING PROTEIN, ALLERGEN, ALLERGY, CROSS-REACTIVITY, HEV B 8
4r3b:A (ALA217) to (HIS289) CRYSTAL STRUCTURE OF SHV-1 B-LACTAMASE IN COMPLEX WITH 6B- (HYDROXYMETHYL)PENICILLANIC ACID SULFONE PSR-283A | CLASS A BETA-LACTAMASE, HYDROLASE, INACTIVATE B-LACTAM ANTIBIOTICS
3n84:E (PRO66) to (ARG136) CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A 23-MEMBERED MACROCYCLIC LIGAND HAVING THE SEQUENCE PYVNVP | LIGAND PREORGANIZATION, MACROCYCLES, MACROCYCLIC LIGANDS, GOLGI APPARATUS, HOST-VIRUS INTERACTION, PHOSPHOPROTEIN, PROTEIN BINDING- PEPTIDE COMPLEX
3n84:F (PRO66) to (ARG136) CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A 23-MEMBERED MACROCYCLIC LIGAND HAVING THE SEQUENCE PYVNVP | LIGAND PREORGANIZATION, MACROCYCLES, MACROCYCLIC LIGANDS, GOLGI APPARATUS, HOST-VIRUS INTERACTION, PHOSPHOPROTEIN, PROTEIN BINDING- PEPTIDE COMPLEX
3nbl:A (ARG236) to (ALA307) CRYSTAL STRUCTURE OF BLAC-E166A COVALENTLY BOUND WITH CEFUROXIME | PENICILLIN BINDING PROTEIN, BETA-LACTAM COVALENT ADDUCT, HYDROLASE- ANTIBIOTIC COMPLEX
3nbv:B (SER203) to (GLY271) X-RAY STRUCTURE OF KETOHEXOKINASE IN COMPLEX WITH AMP-PNP AND FRUCTOSE | KETOHEXOKINASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ndg:A (ARG236) to (LEU306) CRYSTAL STRUCTURE OF BLAC-E166A COVALENTLY BOUND WITH METHICILLIN | PENICILLIN BINDING PROTEIN, BETA-LACTAM COVALENT ADDUCT, HYDROLASE- ANTIBIOTIC COMPLEX
3cpt:A (ARG46) to (ALA111) MP1-P14 SCAFFOLDING COMPLEX | SCAFFOLD, COMPLEX, ALPHA/BETA, ENDOSOME, MEMBRANE, LYSOSOME, PROTEIN BINDING
3nul:A (LYS43) to (VAL118) PROFILIN I FROM ARABIDOPSIS THALIANA | PROFILIN, CYTOSKELETON, ACTIN BINDING PROTEIN
3cwg:A (SER590) to (GLY656) UNPHOSPHORYLATED MOUSE STAT3 CORE FRAGMENT | STAT3, ACTIVATOR, ACUTE PHASE, ALTERNATIVE SPLICING, CYTOPLASM, DNA-BINDING, NUCLEUS, PHOSPHOPROTEIN, SH2 DOMAIN, TRANSCRIPTION, TRANSCRIPTION REGULATION
3cxl:A (SER55) to (ALA131) CRYSTAL STRUCTURE OF HUMAN CHIMERIN 1 (CHN1) | SH2, RHO-GAP, C1, STRUCTURAL GENOMICS CONSORTIUM, SGC, GTPASE ACTIVATION, METAL-BINDING, PHORBOL-ESTER BINDING, SH2 DOMAIN, ZINC- FINGER, SIGNALING PROTEIN
3o6q:C (PRO179) to (VAL239) THE STRUCTURE OF SPOIISA AND SPOIISB, A TOXIN - ANTITOXIN SYSTEM | GAF DOMAIN, TOXIN-ANTITOXIN, SPORULATION, TOXIN - ANTITOXIN COMPLEX, TOXIN-ANTITOXIN COMPLEX
4s23:A (GLY347) to (ALA403) STRUCTURE OF THE GCPE-HMBPP COMPLEX FROM THERMUS THERMOPHILIUS | TIM BARREL, ALPHA/BETA FOLD, OXIDOREDUCTASE
4s39:A (GLY347) to (ALA403) ISPG IN COMPLEX WITH HMBPP | METHYLERYTHRITOL-PHOSPHATE PATHWAY, TERPENE BIOSYNTHESIS, IRON-SULFUR ENZYMES, REACTION MECHANISMS, DRUG DEVELOPMENT, OXIDOREDUCTASE
4s3a:A (GLY347) to (ALA403) ISPG IN COMPLEX WITH INTERMEDIATE I | METHYLERYTHRITOL-PHOSPHATE PATHWAY, TERPENE BIOSYNTHESIS, IRON-SULFUR ENZYMES, REACTION MECHANISMS, DRUG DEVELOPMENT, OXIDOREDUCTASE
4s3b:A (GLY347) to (THR400) ISPG IN COMPLEX WITH INTERMEDIATE II | METHYLERYTHRITOL-PHOSPHATE PATHWAY, TERPENE BIOSYNTHESIS, IRON-SULFUR ENZYMES, REACTION MECHANISMS, DRUG DEVELOPMENT, OXIDOREDUCTASE
4s3c:A (GLY347) to (ALA403) ISPG IN COMPLEX WITH EPOXIDE INTERMEDIATE | METHYLERYTHRITOL-PHOSPHATE PATHWAY, TERPENE BIOSYNTHESIS, IRON-SULFUR ENZYMES, REACTION MECHANISMS, DRUG DEVELOPMENT, OXIDOREDUCTASE
4s3d:A (GLY347) to (ALA403) ISPG IN COMPLEX WITH PPI | METHYLERYTHRITOL-PHOSPHATE PATHWAY, TERPENE BIOSYNTHESIS, IRON-SULFUR ENZYMES, REACTION MECHANISMS, DRUG DEVELOPMENT, OXIDOREDUCTASE
3ob1:B (THR273) to (GLY335) CRYSTAL STRUCTURE OF C-CBL TKB DOMAIN IN COMPLEX WITH DOUBLE PHOSPHORYLATED SPRY2 PEPTIDE | PROTEIN-PEPTIDE COMPLEX, DOUBLE PHOSPHORYLATION, COMPLEX, E3 UBIQUITIN LIGASE, SPRY2, PHOSPHORYLATION, LIGASE-SIGNALING PROTEIN COMPLEX
3dba:B (GLY141) to (LEU224) CRYSTAL STRUCTURE OF THE CGMP-BOUND GAF A DOMAIN FROM THE PHOTORECEPTOR PHOSPHODIESTERASE 6C | 3', 5' CGMP, GAF DOMAIN, CYCLIC NUCLEOTIDE PHOSPHODIESTERASE, CGMP, HYDROLASE, LIPOPROTEIN, MEMBRANE, PRENYLATION, SENSORY TRANSDUCTION, VISION
3oov:A (VAL72) to (LYS164) CRYSTAL STRUCTURE OF A METHYL-ACCEPTING CHEMOTAXIS PROTEIN, RESIDUES 122 TO 287 | STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, SIGNALING PROTEIN
3oov:B (GLY71) to (LEU163) CRYSTAL STRUCTURE OF A METHYL-ACCEPTING CHEMOTAXIS PROTEIN, RESIDUES 122 TO 287 | STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, SIGNALING PROTEIN
3oph:A (ALA217) to (ILE287) ESBL R164S MUTANT OF SHV-1 BETA-LACTAMASE | CLASS A BETA-LACTAMASE, HYDROLASE
3opr:A (ALA217) to (HIS289) ESBL R164H MUTANT OF SHV-1 BETA-LACTAMASE COMPLEXED TO SA2-13 | CLASS A BETA-LACTAMASE, HYDROLASE
4de3:A (SER220) to (LEU290) CTX-M-9 CLASS A BETA-LACTAMASE COMPLEXED WITH COMPOUND 4 | CTX-M, BETA-LACTAMASE, MOLECULAR DOCKING, FRAGMENT, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3p09:A (ARG212) to (LYS287) CRYSTAL STRUCTURE OF BETA-LACTAMASE FROM FRANCISELLA TULARENSIS | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, ALPHA-BETA SANDWICH, CYTOSOL, HYDROLASE
3p09:B (GLY209) to (TYR286) CRYSTAL STRUCTURE OF BETA-LACTAMASE FROM FRANCISELLA TULARENSIS | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, ALPHA-BETA SANDWICH, CYTOSOL, HYDROLASE
5hl6:B (GLY83) to (ALA169) CRYSTAL STRUCTURE OF A PUTATIVE GAF SENSOR PROTEIN FROM BURKHOLDERIA VIETNAMIENSIS | SSGCID, BURKHOLDERIA VIETNAMIENSI, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
4dn0:A (ASP230) to (GLN308) PELD 156-455 FROM PSEUDOMONAS AERUGINOSA PA14 IN COMPLEX WITH C-DI-GMP | GAF DOMAIN, GGDEF DOMAIN, C-DI-GMP RECEPTOR, BACTERIAL INNER MEMBRANE, NUCLEOTIDE-BINDING PROTEIN
5hmq:A (LEU565) to (ARG626) XYLOSE ISOMERASE-LIKE TIM BARREL/4-HYDROXYPHENYLPYRUVATE DIOXYGENASE FUSION PROTEIN | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE, XYLOSE ISOMERASE-LIKE TIM BARREL, OXIDOREDUCTASE, LYASE
5hmq:B (ASP562) to (ARG626) XYLOSE ISOMERASE-LIKE TIM BARREL/4-HYDROXYPHENYLPYRUVATE DIOXYGENASE FUSION PROTEIN | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE, XYLOSE ISOMERASE-LIKE TIM BARREL, OXIDOREDUCTASE, LYASE
5hmq:C (ASP561) to (ALA623) XYLOSE ISOMERASE-LIKE TIM BARREL/4-HYDROXYPHENYLPYRUVATE DIOXYGENASE FUSION PROTEIN | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE, XYLOSE ISOMERASE-LIKE TIM BARREL, OXIDOREDUCTASE, LYASE
5hmq:D (GLU563) to (ALA625) XYLOSE ISOMERASE-LIKE TIM BARREL/4-HYDROXYPHENYLPYRUVATE DIOXYGENASE FUSION PROTEIN | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE, XYLOSE ISOMERASE-LIKE TIM BARREL, OXIDOREDUCTASE, LYASE
5hmq:E (GLU563) to (GLY628) XYLOSE ISOMERASE-LIKE TIM BARREL/4-HYDROXYPHENYLPYRUVATE DIOXYGENASE FUSION PROTEIN | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE, XYLOSE ISOMERASE-LIKE TIM BARREL, OXIDOREDUCTASE, LYASE
5hmq:F (LEU565) to (ARG626) XYLOSE ISOMERASE-LIKE TIM BARREL/4-HYDROXYPHENYLPYRUVATE DIOXYGENASE FUSION PROTEIN | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE, XYLOSE ISOMERASE-LIKE TIM BARREL, OXIDOREDUCTASE, LYASE
5i6i:A (ASP1094) to (LEU1211) CRYSTAL STRUCTURE OF A DBCCP-VARIANT OF CHAETOMIUM THERMOPHILUM ACETYL-COA CARBOXYLASE | CARBOXYLASE, FATTY ACID METABOLISM, MULTIENZYME, CARRIER PROTEIN- DEPENDENT ENZYME, LIGASE
4uqi:M (ASN27) to (TYR92) AP2 CONTROLS CLATHRIN POLYMERIZATION WITH A MEMBRANE- ACTIVATED SWITCH | ENDOCYTOSIS, PROTEIN TRANSPORT, LIPID BINDING
4ebl:B (ARG220) to (ALA293) BLAC E166A FAROPENEM ACYL-INTERMEDIATE COMPLEX | AMBLER CLASS A BETA-LACTAMASE, BETA-LACTAMASE, SERINE HYDROLASE, ESTERASE, HYDROLASE-ANTIBIOTIC COMPLEX
4ebl:D (GLY217) to (ALA293) BLAC E166A FAROPENEM ACYL-INTERMEDIATE COMPLEX | AMBLER CLASS A BETA-LACTAMASE, BETA-LACTAMASE, SERINE HYDROLASE, ESTERASE, HYDROLASE-ANTIBIOTIC COMPLEX
4ebp:C (ARG220) to (ALA293) BLAC E166A CEFOTAXIME ACYL-INTERMEDIATE COMPLEX | AMBLER CLASS A BETA-LACTAMASE, BETA-LACTAMASE, SERINE HYDROLASE, ESTERASE, HYDROLASE-ANTIBIOTIC COMPLEX
4ebp:D (ARG220) to (ALA293) BLAC E166A CEFOTAXIME ACYL-INTERMEDIATE COMPLEX | AMBLER CLASS A BETA-LACTAMASE, BETA-LACTAMASE, SERINE HYDROLASE, ESTERASE, HYDROLASE-ANTIBIOTIC COMPLEX
5int:B (VAL329) to (GLU397) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF COENZYME A BIOSYNTHESIS BIFUNCTIONAL PROTEIN COABC | PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE, CARBOXY-LYASES, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, LYASE
4etz:A (LEU231) to (SER309) CRYSTAL STRUCTURE OF PELD 158-CT FROM PSEUDOMONAS AERUGINOSA PAO1 | C-DI-GMP, SIGNALING PROTEIN
4etz:B (LEU231) to (ARG311) CRYSTAL STRUCTURE OF PELD 158-CT FROM PSEUDOMONAS AERUGINOSA PAO1 | C-DI-GMP, SIGNALING PROTEIN
4eu0:A (LEU231) to (LEU314) CRYSTAL STRUCTURE OF PELD 158-CT FROM PSEUDOMONAS AERUGINOSA PAO1 | C-DI-GMP, SIGNALING PROTEIN
4euv:A (ASP230) to (GLN308) CRYSTAL STRUCTURE OF PELD 158-CT FROM PSEUDOMONAS AERUGINOSA PAO1, IN COMPLEX WITH C-DI-GMP, FORM 1 | C-DI-GMP, SIGNALING PROTEIN
3qai:A (SER203) to (GLY271) X-RAY STRUCTURE OF KETOHEXOKINASE IN COMPLEX WITH A PYRIMIDOPYRIMIDINE ANALOG 3 | KETOHEXOKINASE, ATP BINDING, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5j3x:E (THR273) to (GLY335) STRUCTURE OF C-CBL Y371F | UBIQUITIN LIGASE, RING E3, LIGASE
4fcf:A (ALA217) to (HIS289) K234R: APO STRUCTURE OF INHIBITOR RESISTANT BETA-LACTAMASE | CLASS A BETA-LACTAMSE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3r7w:B (ILE225) to (ASP323) CRYSTAL STRUCTURE OF GTR1P-GTR2P COMPLEX | RAG GTPASES, GTR1P, GTR2P, MTOR, PROTEIN TRANSPORT
3r7w:D (ILE225) to (ASP323) CRYSTAL STRUCTURE OF GTR1P-GTR2P COMPLEX | RAG GTPASES, GTR1P, GTR2P, MTOR, PROTEIN TRANSPORT
3rfb:A (GLY77) to (THR154) STRUCTURE OF FRMSR | FRMSR, GAF, OXIDOREDUCTASE, SME
3rfb:B (GLY77) to (THR154) STRUCTURE OF FRMSR | FRMSR, GAF, OXIDOREDUCTASE, SME
4fxi:A (SER20) to (LEU95) CRYSTAL STRUCTURE OF THE ISOLATED E. COLI RELE TOXIN, P21 FORM | TOXIN/ANTITOXIN SYSTEM, TOXIN, NUCLEASE, TRANSLATIONAL CONTROL,STRESS RESPONSE, RELB, RIBOSOME, B-ME ON CYS50
4g3v:A (GLY76) to (GLU164) CRYSTAL STRUCTURE OF A. AEOLICUS NLH2 GAF DOMAIN IN AN INACTIVE STATE | GAF DOMAIN, TRANSCRIPTION REGULATOR
4g3v:B (GLY76) to (GLU164) CRYSTAL STRUCTURE OF A. AEOLICUS NLH2 GAF DOMAIN IN AN INACTIVE STATE | GAF DOMAIN, TRANSCRIPTION REGULATOR
4g3w:A (GLY75) to (SER160) CRYSTAL STRUCTURE OF A. AEOLICUS NLH1 GAF DOMAIN IN AN INACTIVE STATE | GAF DOMAIN, TRANSCRIPTION REGULATOR
4gd8:A (ALA217) to (HIS289) SHV-1 BETA-LACTAMASE IN COMPLEX WITH PENAM SULFONE SA3-53 | CLASS A BETA-LACTAMASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4gdb:A (ALA217) to (HIS289) SHV-1 IN COMPLEX WITH 4H-PYRAZOLO[1,5-C][1,3]THIAZOLE CONTAINING PENEM INHIBITOR | CLASS A BETA-LACTAMASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5tqi:B (VAL159) to (GLY234) CRYSTAL STRUCTURE OF A PYRIDOXAL KINASE FROM BURKHOLDERIA MULTIVORANS | SSGCID, BURKHOLDERIA MULTIVORANS, PYRIDOXAL KINASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
1aya:A (THR12) to (GLU83) CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO- TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE | HYDROLASE(SH2 DOMAIN)
1blc:A (GLY217) to (PHE290) INHIBITION OF BETA-LACTAMASE BY CLAVULANATE: TRAPPED INTERMEDIATES IN CRYOCRYSTALLOGRAPHIC STUDIES | HYDROLASE(ACTING IN CYCLIC AMIDES)
3s8n:A (PRO66) to (ARG136) CRYSTAL STRUCTURE OF THE GRB2 SH2 DOMAIN IN COMPLEX WITH A PYXN- DERIVED TRIPEPTIDE | GRB2 SH2 DOMAIN, PHOSPHOTYROSINE-CONTAINING TRIPEPTIDE, SIGNALING PROTEIN-ANTAGONIST COMPLEX
2pnb:A (GLU30) to (GLU100) STRUCTURE OF AN SH2 DOMAIN OF THE P85 ALPHA SUBUNIT OF PHOSPHATIDYLINOSITOL-3-OH KINASE | SIGNALLING PROTEIN
3g34:B (GLY217) to (LEU290) CTX-M-9 CLASS A BETA-LACTAMASE COMPLEXED WITH COMPOUND 11 (1CE) | CTX-M, BETA-LACTAMASE, MOLECULAR DOCKING, FRAGMENT, INHIBITOR, ANTIBIOTIC RESISTANCE, HYDROLASE/HYDROLASE INHIBITOR, PLASMID
2dmw:A (PHE32) to (GLY98) SOLUTION STRUCTURE OF THE LONGIN DOMAIN OF SYNAPTOBREVIN- LIKE PROTEIN 1 | LONGIN DOMAIN, BETA(2)-ALPHA-BETA(3)-ALPHA(2), STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, MEMBRANE PROTEIN
3h1t:A (PRO99) to (GLU157) THE FRAGMENT STRUCTURE OF A PUTATIVE HSDR SUBUNIT OF A TYPE I RESTRICTION ENZYME FROM VIBRIO VULNIFICUS YJ016 | HYDROLASE, RESTRICTION ENZYME HSDR, ATP-BINDING, NUCLEOTIDE- BINDING
4yof:A (GLY119) to (ALA203) DOSS GAFA DOMAIN REDUCED NITRIC OXIDE BOUND CRYSTAL STRUCTURE | DOSS, TUBERCULOSIS, HEME, GAS SENSOR, OXIDOREDUCTASE
4yof:B (GLY119) to (ALA203) DOSS GAFA DOMAIN REDUCED NITRIC OXIDE BOUND CRYSTAL STRUCTURE | DOSS, TUBERCULOSIS, HEME, GAS SENSOR, OXIDOREDUCTASE
2vgl:M (ARG26) to (TYR92) AP2 CLATHRIN ADAPTOR CORE | CYTOPLASMIC VESICLE, ALTERNATIVE SPLICING, ENDOCYTOSIS, LIPID-BINDING, GOLGI APPARATUS, ADAPTOR, MEMBRANE, TRANSPORT, COATED PIT, PHOSPHORYLATION, PROTEIN TRANSPORT
2vjw:A (ASN292) to (MSE372) CRYSTAL STRUCTURE OF THE SECOND GAF DOMAIN OF DEVS FROM MYCOBACTERIUM SMEGMATIS | GAF, HISTIDINE KINASE, HYPOXIA SENSING, HYDROLASE
1ghp:A (LEU220) to (PHE290) STRUCTURES OF THE ACYL-ENZYME COMPLEX OF THE STAPHYLOCOCCUS AUREUS BETA-LACTAMASE MUTANT GLU166ASP:ASN170GLN WITH DEGRADED BENZYLPENICILLIN | HYDROLASE, ANTIBIOTIC RESISTANCE, BETA-LACTAM HYDROLYSIS, BENZYLPENICILLIN, CEPHALORIDINE
1tdl:A (ALA217) to (HIS289) STRUCTURE OF SER130GLY SHV-1 BETA-LACTAMASE | CLASS A BETA-LACTAMASE, PENICILLINASE, BETA-LACTAM HYDROLASE, DETERGENT BINDING, DRUG DESIGN
2w9j:B (SER4) to (VAL77) THE CRYSTAL STRUCTURE OF SRP14 FROM THE SCHIZOSACCHAROMYCES POMBE SIGNAL RECOGNITION PARTICLE | SCHIZOSACCHAROMYCES POMBE, RADIATION-INDUCED PHASING, RNA-BINDING, RIBONUCLEOPROTEIN, SIGNAL RECOGNITION PARTICLE, SIGNALING PROTEIN, ARSENIC, ALU-DOMAIN, CACODYLATE
4lrx:D (CYS116) to (MET212) CRYSTAL STRUCTURE OF THE E.COLI DHAR(N)-DHAK COMPLEX | COILED-COIL, HELIX ROTATION, PAS, GAF, TRANSCRIPTION REGULATION COMPLEX, TRANSFERASE-TRANSCRIPTION REGULATOR COMPLEX
1ifq:A (SER26) to (HIS99) SEC22B N-TERMINAL DOMAIN | FIVE-STRANDED ANTI-PARALLEL BETA SHEET, ALPHA/BETA 3-LAYER SANDWICH, PROTEIN TRANSPORT
1ifq:B (ARG28) to (HIS99) SEC22B N-TERMINAL DOMAIN | FIVE-STRANDED ANTI-PARALLEL BETA SHEET, ALPHA/BETA 3-LAYER SANDWICH, PROTEIN TRANSPORT
4mbf:A (ALA217) to (HIS289) CRYSTAL STRUCTURE OF PENAM SULFONE PSR-4-157 BOUND TO SHV-1 BETA- LACTAMASE | CLASS A BETA-LACTAMASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4mbk:A (ASP214) to (ILE287) CRYSTAL STRUCTURE OF K234R INHIBITOR-RESISTANT VARIANT OF SHV BETA- LACTAMASE IN COMPLEX WITH SA2-13 | CLASS A BETA-LACTAMASE, HYDROLASE
4mcw:A (GLY71) to (ALA178) METALLO-ENZYME FROM P. MARINA | STRUCTURAL GENOMICS, OXFORD PROTEIN PRODUCTION FACILITY, OPPF, HYDROLASE
2ivz:C (PRO89) to (LEU157) STRUCTURE OF TOLB IN COMPLEX WITH A PEPTIDE OF THE COLICIN E9 T-DOMAIN | PROTEIN TRANSPORT/HYDROLASE, PROTEIN-PROTEIN INTERACTION, PROTEIN TRANSPORT, BACTERIOCIN TRANSPORT, TOLB, COLICIN, PLASMID, NUCLEASE, HYDROLASE, TRANSPORT, ANTIBIOTIC, PERIPLASMIC, BACTERIOCIN, NATIVELY DISORDERED PROTEINS, PROTEIN TRANSPORT/HYDROLASE COMPLEX, ENDONUCLEASE, ANTIMICROBIAL, TRANSLOCATION
2ivz:D (PRO89) to (LEU157) STRUCTURE OF TOLB IN COMPLEX WITH A PEPTIDE OF THE COLICIN E9 T-DOMAIN | PROTEIN TRANSPORT/HYDROLASE, PROTEIN-PROTEIN INTERACTION, PROTEIN TRANSPORT, BACTERIOCIN TRANSPORT, TOLB, COLICIN, PLASMID, NUCLEASE, HYDROLASE, TRANSPORT, ANTIBIOTIC, PERIPLASMIC, BACTERIOCIN, NATIVELY DISORDERED PROTEINS, PROTEIN TRANSPORT/HYDROLASE COMPLEX, ENDONUCLEASE, ANTIMICROBIAL, TRANSLOCATION
1vhm:A (GLY92) to (ALA170) CRYSTAL STRUCTURE OF AN HYPOTHETICAL PROTEIN | STRUCTURAL GENOMICS, UNKNOWN FUNCTION
1vhm:B (GLY92) to (ALA170) CRYSTAL STRUCTURE OF AN HYPOTHETICAL PROTEIN | STRUCTURAL GENOMICS, UNKNOWN FUNCTION
3zdj:A (LEU220) to (HIS289) ANCESTRAL (ENCA) BETA-LACTAMASE CLASS A | HYDROLASE, ANTIBIOTIC RESISTANCE
2jkt:M (ALA28) to (TYR92) AP2 CLATHRIN ADAPTOR CORE WITH CD4 DILEUCINE PEPTIDE RM( PHOSPHOS)EIKRLLSE Q TO E MUTANT | ALTERNATIVE SPLICING, PHOSPHOPROTEIN, PHOSPHORYLATION, PROTEIN TRANSPORT, ADAPTOR, MEMBRANE, TRANSPORT, COATED PIT, ENDOCYTOSIS, CELL MEMBRANE, LIPID-BINDING
2jkt:U (ALA28) to (TYR92) AP2 CLATHRIN ADAPTOR CORE WITH CD4 DILEUCINE PEPTIDE RM( PHOSPHOS)EIKRLLSE Q TO E MUTANT | ALTERNATIVE SPLICING, PHOSPHOPROTEIN, PHOSPHORYLATION, PROTEIN TRANSPORT, ADAPTOR, MEMBRANE, TRANSPORT, COATED PIT, ENDOCYTOSIS, CELL MEMBRANE, LIPID-BINDING
1ka7:A (SER12) to (GLN88) SAP/SH2D1A BOUND TO PEPTIDE N-Y-C | SH2 DOMAIN, PROTEIN-PEPTIDE COMPLEX, IMMUNE SYSTEM
1kge:A (LEU220) to (PHE290) STRUCTURE OF BETA-LACTAMASE ASN 170 MET MUTANT | HYDROLASE, ANTIBIOTIC RESISTANCE, SIGNAL, PLASMID, TRANSPOSABLE ELEMENT, BETA-LACTAMASE
5d5q:B (PRO82) to (GLY155) HCGB FROM METHANOCALDOCOCCUS JANNASCHII WITH THE PYRIDINOL DERIVED FROM FEGP COFACTOR OF [FE]-HYDROGENASE | GUANYLYLTRANSFERASE, TRANSFERASE
3a8i:A (ASN160) to (GLY214) CRYSTAL STRUCTURE OF ET-EHRED-5-CH3-THF COMPLEX | GLYCINE CLEAVAGE SYSTEM, AMINOTRANSFERASE, TRANSFERASE, LIPOYL, TRANSFERASE-TRANSPORT PROTEIN COMPLEX
3kyq:A (ARG33) to (GLN104) LIPID-INDUCED CONFORMATIONAL SWITCH CONTROLS FUSION ACTIVITY OF LONGIN DOMAIN SNARE YKT6 | V-SNARE HOMOLOG, LIPID BINDING, CYTOPLASMIC VESICLE, ER-GOLGI TRANSPORT, GOLGI APPARATUS, LIPOPROTEIN, PALMITATE, PRENYLATION, PROTEIN TRANSPORT, TRANSFERASE, TRANSPORT
3ao0:B (VAL207) to (LYS287) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND (S)-2-AMINO-1-PROPANOL | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN, TIM BARREL
3ao0:D (ARG206) to (GLN286) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND (S)-2-AMINO-1-PROPANOL | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN, TIM BARREL
2a9s:A (SER81) to (GLY167) THE CRYSTAL STRUCTURE OF COMPETENCE/DAMAGE INDUCIBLE PROTEIN CIHA FROM AGROBACTERIUM TUMEFACIENS | APC5759, ATC1417, MCSG, COMPETENCE, DAMAGE INDUCIBLE, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, PSI, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
2a9s:B (SER81) to (GLN165) THE CRYSTAL STRUCTURE OF COMPETENCE/DAMAGE INDUCIBLE PROTEIN CIHA FROM AGROBACTERIUM TUMEFACIENS | APC5759, ATC1417, MCSG, COMPETENCE, DAMAGE INDUCIBLE, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, PSI, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
3mf0:A (MET410) to (LYS518) CRYSTAL STRUCTURE OF PDE5A GAF DOMAIN (89-518) | GAF, CGMP SIGNAL, HYDROLASE
3mf0:B (TYR411) to (LYS518) CRYSTAL STRUCTURE OF PDE5A GAF DOMAIN (89-518) | GAF, CGMP SIGNAL, HYDROLASE
3bfg:A (SER220) to (GLU288) CLASS A BETA-LACTAMASE SED-G238C COMPLEXED WITH MEROPENEM | HYDROLASE, BETA-LACTAMASE, CLASS A, SED-G238C, MEROPENEM, ACYL-ENZYME
3bfg:D (GLY217) to (GLU288) CLASS A BETA-LACTAMASE SED-G238C COMPLEXED WITH MEROPENEM | HYDROLASE, BETA-LACTAMASE, CLASS A, SED-G238C, MEROPENEM, ACYL-ENZYME
3mmh:A (GLY83) to (SER163) X-RAY STRUCTURE OF FREE METHIONINE-R-SULFOXIDE REDUCTASE FROM NEISSERIA MENINGITIDIS IN COMPLEX WITH ITS SUBSTRATE | OXIDOREDUCTASE
3mmh:B (GLY83) to (VAL167) X-RAY STRUCTURE OF FREE METHIONINE-R-SULFOXIDE REDUCTASE FROM NEISSERIA MENINGITIDIS IN COMPLEX WITH ITS SUBSTRATE | OXIDOREDUCTASE
3obf:A (ASP216) to (GLY297) CRYSTAL STRUCTURE OF PUTATIVE TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; TARGETED DOMAIN 129...302 | STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, TRANSCRIPTION REGULATOR
3opp:A (ALA217) to (HIS289) ESBL R164S MUTANT OF SHV-1 BETA-LACTAMASE COMPLEXED WITH SA2-13 | CLASS A BETA-LACTAMASE, HYDROLASE
4dmz:A (LEU232) to (LEU307) PELD 156-455 FROM PSEUDOMONAS AERUGINOSA PA14, APO FORM | GAF DOMAIN, GGDEF DOMAIN, C-DI-GMP RECEPTOR, INNER MEMBRANE, GRAM NEGATIVE BACTERIA, NUCLEOTIDE-BINDING PROTEIN
4dmz:B (ASP230) to (SER309) PELD 156-455 FROM PSEUDOMONAS AERUGINOSA PA14, APO FORM | GAF DOMAIN, GGDEF DOMAIN, C-DI-GMP RECEPTOR, INNER MEMBRANE, GRAM NEGATIVE BACTERIA, NUCLEOTIDE-BINDING PROTEIN
3e0y:A (ILE148) to (ARG238) THE CRYSTAL STRUCTURE OF A CONSERVED DOMAIN FROM A PROTEIN OF GEOBACTER SULFURREDUCENS PCA | APC87688.2, CONSERVED DOMAIN, GEOBACTER SULFURREDUCENS PCA, STRUCTURAL GENOMICS, PSI-2, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, PROTEIN STRUCTURE INITIATIVE, UNKNOWN FUNCTION
5hw3:A (ARG219) to (ALA290) CRYSTAL STRUCTURE OF A BETA LACTAMASE FROM BURKHOLDERIA VIETNAMIENSIS | SSGCID, BETA LACTAMASE, BURKHOLDERIA VIETNAMIENSIS, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, HYDROLASE
4fh4:A (ALA217) to (HIS289) HIGH-RESOLUTION STRUCTURE OF APO WT SHV-1 BETA-LACTAMASE | CLASS A BETA-LACTAMASE, HYDROLASE
4g3k:A (LYS79) to (ARG169) CRYSTAL STRUCTURE OF A. AEOLICUS NLH1 GAF DOMAIN IN AN INACTIVE STATE | GAF DOMAIN, TRANSCRIPTION REGULATOR
4g3k:B (ILE76) to (LEU172) CRYSTAL STRUCTURE OF A. AEOLICUS NLH1 GAF DOMAIN IN AN INACTIVE STATE | GAF DOMAIN, TRANSCRIPTION REGULATOR