3e91:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV MPRO MUTANT IN P21 AT PH6.9 | SARS CORONAVIRUS PROTEASE, HYDROLASE
3e91:B (GLY11) to (ASN51) CRYSTAL STRUCTURE OF SARS-COV MPRO MUTANT IN P21 AT PH6.9 | SARS CORONAVIRUS PROTEASE, HYDROLASE
3ea8:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE TRIPLE MUTANT STI/A IN SPACE GROUP C2 | SARS CORONAVIRUS MAIN PROTEASE 3C-LIKE PROTEASE MUTANT EXTRA HELICAL DOMAIN, CYTOPLASM, HYDROLASE, MEMBRANE, METAL- BINDING, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
3ea9:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE QUADRUPLE MUTANT STIF/A WITH ONE MOLECULE IN ONE ASYMMETRIC UNIT | SARS CORONAVIRUS MAIN PROTEASE MUTANT, 3C-LIKE PROTEASE, EXTRA HELICAL DOMAIN, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA- BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
2alv:A (SER10) to (ARG60) X-RAY STRUCTURAL ANALYSIS OF SARS CORONAVIRUS 3CL PROTEINASE IN COMPLEX WITH DESIGNED ANTI-VIRAL INHIBITORS | SARS, CORONAVIRUS, 3C, 3CL, 3CLPRO, PROTEINASE, PROTEASE, INHIBITOR, ANTI-VIRAL, HYDROLASE
2amd:A (SER10) to (ARG60) CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N9 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
2amd:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N9 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
2amp:A (SER10) to (VAL60) CRYSTAL STRUCTURE OF PORCINE TRANSMISSIBLE GASTROENTERITIS VIRUS MPRO IN COMPLEX WITH AN INHIBITOR N1 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
2amp:B (SER10) to (VAL60) CRYSTAL STRUCTURE OF PORCINE TRANSMISSIBLE GASTROENTERITIS VIRUS MPRO IN COMPLEX WITH AN INHIBITOR N1 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
4wmd:A (SER10) to (SER60) CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE MERS-COV 3CL PROTEASE (C148A) IN SPACEGROUP C2221 | 3CL PROTEASE, MERS, CORONAVIRUS, HYDROLASE
4wmd:C (SER10) to (MET61) CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE MERS-COV 3CL PROTEASE (C148A) IN SPACEGROUP C2221 | 3CL PROTEASE, MERS, CORONAVIRUS, HYDROLASE
4wme:A (SER10) to (MET61) CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE MERS-COV 3CL PROTEASE (C148A) IN SPACEGROUP C2 | MERS, CORONAVIRUS, 3CL PROTEASE, HYDROLASE
4wme:C (GLY11) to (MET61) CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE MERS-COV 3CL PROTEASE (C148A) IN SPACEGROUP C2 | MERS, CORONAVIRUS, 3CL PROTEASE, HYDROLASE
4wme:D (GLY11) to (MET61) CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE MERS-COV 3CL PROTEASE (C148A) IN SPACEGROUP C2 | MERS, CORONAVIRUS, 3CL PROTEASE, HYDROLASE
4wmf:B (SER10) to (MET61) CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE MERS-COV 3CL PROTEASE (C148A) IN SPACEGROUP P212121 | MES, 3CL PROTEASE, CORONAVIRUS, HYDROLASE
4wmf:C (GLY11) to (MET61) CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE MERS-COV 3CL PROTEASE (C148A) IN SPACEGROUP P212121 | MES, 3CL PROTEASE, CORONAVIRUS, HYDROLASE
2op9:A (SER10) to (LYS61) SUBSTRATE SPECIFICITY PROFILING AND IDENTIFICATION OF A NEW CLASS OF INHIBITOR FOR THE MAJOR PROTEASE OF THE SARS CORONAVIRUS | SARS, 3CLPRO, PROTEINASE, PROTEASE, HYDROLASE
2op9:B (SER10) to (LYS61) SUBSTRATE SPECIFICITY PROFILING AND IDENTIFICATION OF A NEW CLASS OF INHIBITOR FOR THE MAJOR PROTEASE OF THE SARS CORONAVIRUS | SARS, 3CLPRO, PROTEINASE, PROTEASE, HYDROLASE
4wy3:A (GLY11) to (LYS61) STRUCTURE OF SARS-3CL PROTEASE COMPLEX WITH A PHENYLBENZOYL (R,S)-N- DECALIN TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4hi3:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF DIMERIC R298A MUTANT OF SARS CORONAVIRUS MAIN PROTEASE | CHYMOTRYPSIN-LIKE PROTEIN, PROTEASE, CYTOSOL, HYDROLASE
4hi3:B (SER10) to (ASN51) CRYSTAL STRUCTURE OF DIMERIC R298A MUTANT OF SARS CORONAVIRUS MAIN PROTEASE | CHYMOTRYPSIN-LIKE PROTEIN, PROTEASE, CYTOSOL, HYDROLASE
3f9f:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF THE F140A MUTANT OF SARS-CORONOVIRUS 3C-LIKE PROTEASE AT PH 6.0 | PROTEASE, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
3f9f:B (SER10) to (ARG60) CRYSTAL STRUCTURE OF THE F140A MUTANT OF SARS-CORONOVIRUS 3C-LIKE PROTEASE AT PH 6.0 | PROTEASE, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
3f9g:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF THE F140A MUTANT OF SARS-CORONOVIRUS 3C-LIKE PROTEASE AT PH 6.5 | PROTEASE, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
3f9g:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF THE F140A MUTANT OF SARS-CORONOVIRUS 3C-LIKE PROTEASE AT PH 6.5 | PROTEASE, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
2bx3:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (P43212) | SARS, HYDROLASE, ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A- HELICES, VIRAL PROTEIN
4xfq:A (SER10) to (LEU60) CRYSTAL STRUCTURE BASIS FOR PEDV 3C LIKE PROTEASE | PORCINE EPIDEMIC DIARRHEA VIRUS, 3C-LIKE PROTEASE, HYDROLASE
4xfq:B (SER10) to (LEU60) CRYSTAL STRUCTURE BASIS FOR PEDV 3C LIKE PROTEASE | PORCINE EPIDEMIC DIARRHEA VIRUS, 3C-LIKE PROTEASE, HYDROLASE
2c3s:A (SER10) to (ARG60) STRUCTURE OF SARS COV MAIN PROTEINASE AT 1.9 A (PH6.5) | SARS COV, 3C-LIKE PROTEASE, MAIN PROTEASE, HYDROLASE
2pwx:A (ALA11) to (LYS61) CRYSTAL STRUCTURE OF G11A MUTANT OF SARS-COV 3C-LIKE PROTEASE | CHYMOTRYPSIN FOLD, HYDROLASE
3sn8:A (GLY11) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH CM- FF-H (SOAKING) | 3C-LIKE PROTEINASE, PROTEASE, CM-FF-H, ACTIVE SITE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3sna:A (SER10) to (ARG60) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AC- NSFSQ-H (SOAKING) | 3C-LIKE PROTEINASE, PROTEASE, AC-NSFSQ-H, ACTIVE SITE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3snb:A (SER10) to (SER62) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AC- DSFDQ-H (SOAKING) | 3C-LIKE PROTEINASE, PROTEASE, AC-DSFDQ-H, COVALENT BOUND, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3snc:A (SER10) to (SER62) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AC- NSTSQ-H (SOAKING) | 3C-LIKE PROTEINASE, PROTEASE, AC-NSTSQ-H, ACTIVE SITE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3sne:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AC- ESTLQ-H (SOAKING) | SARS CORONAVIRUS MAIN PROTEASE, 3C-LIKE PROTEINASE, PROTEASE, INHIBITOR AC-ESTLQ-H, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2q6f:A (SER10) to (ALA58) CRYSTAL STRUCTURE OF INFECTIOUS BRONCHITIS VIRUS (IBV) MAIN PROTEASE IN COMPLEX WITH A MICHAEL ACCEPTOR INHIBITOR N3 | CORONAVIRUS; IBV; MAIN PROTEASE; 3C-LIKE PROTEINASE; MICHAEL ACCEPTOR INHIBITOR, HYDROLASE
2q6f:B (SER10) to (ALA58) CRYSTAL STRUCTURE OF INFECTIOUS BRONCHITIS VIRUS (IBV) MAIN PROTEASE IN COMPLEX WITH A MICHAEL ACCEPTOR INHIBITOR N3 | CORONAVIRUS; IBV; MAIN PROTEASE; 3C-LIKE PROTEINASE; MICHAEL ACCEPTOR INHIBITOR, HYDROLASE
2q6g:A (SER10) to (ASN51) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE H41A MUTANT IN COMPLEX WITH AN N-TERMINAL SUBSTRATE | CORONAVIRUS; SARS-COV; MAIN PROTEASE; 3C-LIKE PROTEINASE;SUBSTRATE, HYDROLASE
2q6g:B (SER10) to (ARG60) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE H41A MUTANT IN COMPLEX WITH AN N-TERMINAL SUBSTRATE | CORONAVIRUS; SARS-COV; MAIN PROTEASE; 3C-LIKE PROTEINASE;SUBSTRATE, HYDROLASE
2qc2:A (GLY11) to (LYS61) CRYSTAL STRUCTURE OF SEVERE ACUTE RESPIRATORY SYNDROME (SARS) 3C-LIKE PROTEASE ASN214ALA MUTANT | HYDROLASE
2qc2:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SEVERE ACUTE RESPIRATORY SYNDROME (SARS) 3C-LIKE PROTEASE ASN214ALA MUTANT | HYDROLASE
3szn:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AN ALPHA, BETA-UNSATURATED ETHYL ESTER SG75 | SARS CORONAVIRUS MAIN PROTEASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1p9s:A (SER10) to (ILE59) CORONAVIRUS MAIN PROTEINASE (3CLPRO) STRUCTURE: BASIS FOR DESIGN OF ANTI-SARS DRUGS | SARS-COV, HCOV, CORONAVIRUS, TGEV, HYDROLASE
1p9s:B (SER10) to (MSE60) CORONAVIRUS MAIN PROTEINASE (3CLPRO) STRUCTURE: BASIS FOR DESIGN OF ANTI-SARS DRUGS | SARS-COV, HCOV, CORONAVIRUS, TGEV, HYDROLASE
2qiq:A (GLY11) to (LYS61) STRUCTURE-BASED DESIGN AND SYNTHESIS AND BIOLOGICAL EVALUATION OF PEPTIDOMIMETIC SARS-3CLPRO INHIBITORS | HYDROLASE, VIRAL PROTEIN
2d2d:A (GLY11) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR I2 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
2d2d:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR I2 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
1q2w:A (GLY11) to (LYS61) X-RAY CRYSTAL STRUCTURE OF THE SARS CORONAVIRUS MAIN PROTEASE | SARS-COV MAIN PROTEASE, THREE DOMAIN PROTEIN (TWO ANTIPARALLEL BETA BARRELS, ONE ALPHA HELICAL), HYDROLASE
1q2w:B (SER10) to (ARG60) X-RAY CRYSTAL STRUCTURE OF THE SARS CORONAVIRUS MAIN PROTEASE | SARS-COV MAIN PROTEASE, THREE DOMAIN PROTEIN (TWO ANTIPARALLEL BETA BARRELS, ONE ALPHA HELICAL), HYDROLASE
3tit:A (GLY11) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AN ALPHA, BETA-UNSATURATED ETHYL ESTER SG81 | SARS CORONAVIRUS MAIN PROTEASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3tiu:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AN ALPHA,BETA-UNSATURATED ETHYL ESTER INHIBITOR SG82 | CORONAVIRUS MAIN PROTEASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3tlo:A (SER10) to (MET60) CRYSTAL STRUCTURE OF HCOV-NL63 3C-LIKE PROTEASE | HYDROLYSIS, HYDROLASE, PROTEIN BINDING
3tlo:B (SER10) to (MET60) CRYSTAL STRUCTURE OF HCOV-NL63 3C-LIKE PROTEASE | HYDROLYSIS, HYDROLASE, PROTEIN BINDING
3tns:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AN ALPHA, BETA-UNSATURATED ETHYL ESTER INHIBITOR SG83 | 3C-LIKE PROTEASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3tnt:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AN ALPHA, BETA-UNSATURATED ETHYL ESTER INHIBITOR SG85 | 3C-LIKE PROTEASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ylu:A (SER10) to (MET61) X-RAY STRUCTURE OF MERS-COV NSP5 PROTEASE BOUND WITH A NON-COVALENT INHIBITOR | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ylu:B (SER10) to (SER60) X-RAY STRUCTURE OF MERS-COV NSP5 PROTEASE BOUND WITH A NON-COVALENT INHIBITOR | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ylu:C (SER10) to (MET61) X-RAY STRUCTURE OF MERS-COV NSP5 PROTEASE BOUND WITH A NON-COVALENT INHIBITOR | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ylu:D (SER10) to (MET61) X-RAY STRUCTURE OF MERS-COV NSP5 PROTEASE BOUND WITH A NON-COVALENT INHIBITOR | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4yo9:A (SER10) to (ASP51) HKU4 3CLPRO UNBOUND STRUCTURE | HKU4 3CLPRO MPRO NSP5, HYDROLASE
4yoi:A (SER10) to (LYS61) STRUCTURE OF HKU4 3CLPRO BOUND TO NON-COVALENT INHIBITOR 1A | HKU4 3CLPRO MPRO NSP5, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4yoi:B (SER10) to (LYS61) STRUCTURE OF HKU4 3CLPRO BOUND TO NON-COVALENT INHIBITOR 1A | HKU4 3CLPRO MPRO NSP5, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4yoj:A (SER10) to (LYS61) HKU4 3CLPRO BOUND TO NON-COVALENT INHIBITOR 2A | HKU4 3CLPRO MPRO NSP5, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4yoj:B (SER10) to (LYS61) HKU4 3CLPRO BOUND TO NON-COVALENT INHIBITOR 2A | HKU4 3CLPRO MPRO NSP5, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2v6n:A (SER10) to (LYS61) CRYSTAL STRUCTURES OF THE SARS-CORONAVIRUS MAIN PROTEINASE INACTIVATED BY BENZOTRIAZOLE COMPOUNDS | THIOL PROTEASE, RNA REPLICATION, MAIN PROTEINASE, RIBOSOMAL FRAMESHIFT, SARS, PROTEASE, HYDROLASE, POLYPROTEIN, VIRAL PROTEIN
2vj1:A (SER10) to (LYS61) A STRUCTURAL VIEW OF THE INACTIVATION OF THE SARS- CORONAVIRUS MAIN PROTEINASE BY BENZOTRIAZOLE ESTERS | SARS, PROTEASE, HYDROLASE, POLYPROTEIN, THIOL PROTEASE, RIBOSOMAL FRAMESHIFT, SARS CORONAVIRUS MAIN PROTEINASE
2vj1:B (SER10) to (LYS61) A STRUCTURAL VIEW OF THE INACTIVATION OF THE SARS- CORONAVIRUS MAIN PROTEINASE BY BENZOTRIAZOLE ESTERS | SARS, PROTEASE, HYDROLASE, POLYPROTEIN, THIOL PROTEASE, RIBOSOMAL FRAMESHIFT, SARS CORONAVIRUS MAIN PROTEINASE
3v3m:A (SER10) to (LYS61) SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS (SARS-COV) 3CL PROTEASE IN COMPLEX WITH N-[(1R)-2-(TERT-BUTYLAMINO)-2-OXO-1-(PYRIDIN-3-YL) ETHYL]-N-(4-TERT-BUTYLPHENYL)FURAN-2-CARBOXAMIDE INHIBITOR. | CHYMOTRYPSIN LIKE FOLD, VIRAL POLYPEPTIDE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb4:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH B4Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb4:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH B4Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb5:A (SER10) to (ASN51) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH C4Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb6:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH C6Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb6:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH C6Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb7:A (SER10) to (ASN51) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH M4Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb7:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH M4Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2gt7:A (SER10) to (ARG60) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PEPTIDASE AT PH 6.0 IN THE SPACE GROUP P21 | CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, LONG LOOP, ALPHA-HELICAL DOMAIN, DIMER, CATALYTIC DYAD, SPECIFICITY POCKETS, HYDROLASE
2gt7:B (SER10) to (ASN51) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PEPTIDASE AT PH 6.0 IN THE SPACE GROUP P21 | CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, LONG LOOP, ALPHA-HELICAL DOMAIN, DIMER, CATALYTIC DYAD, SPECIFICITY POCKETS, HYDROLASE
2gt8:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PEPTIDASE (WITH AN ADDITIONAL ALA AT THE N-TERMINUS OF EACH PROTOMER) IN THE SPACE GROUP P43212 | CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, LONG LOOP, ALPHA-HELICAL DOMAIN, DIMER, CATALYTIC DYAD, SPECIFICITY POCKETS, HYDROLASE
2gtb:A (SER10) to (ASN51) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PEPTIDASE (WITH AN ADDITIONAL ALA AT THE N-TERMINUS OF EACH PROTOMER) INHIBITED BY AN AZA-PEPTIDE EPOXIDE IN THE SPACE GROUP P43212 | CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, LONG LOOP, ALPHA-HELICAL DOMAIN, DIMER, CATALYTIC DYAD, SPECIFICITY POCKETS, HYDROLASE
2gz7:A (SER10) to (LYS61) STRUCTURE-BASED DRUG DESIGN AND STRUCTURAL BIOLOGY STUDY OF NOVEL NONPEPTIDE INHIBITORS OF SARS-COV MAIN PROTEASE | SARS COV MAIN PROTEASE, HYDROLASE
2gz8:A (GLY11) to (ASN51) STRUCTURE-BASED DRUG DESIGN AND STRUCTURAL BIOLOGY STUDY OF NOVEL NONPEPTIDE INHIBITORS OF SARS-COV MAIN PROTEASE | SARS COV MAIN PROTEASE, HYDROLASE
2gz9:A (SER10) to (ASN51) STRUCTURE-BASED DRUG DESIGN AND STRUCTURAL BIOLOGY STUDY OF NOVEL NONPEPTIDE INHIBITORS OF SARS-COV MAIN PROTEASE | SARS COV MAIN PROTEASE, HYDROLASE
4zuh:A (SER10) to (LEU60) COMPLEX STRUCTURE OF PEDV 3CLPRO MUTANT (C144A) WITH A PEPTIDE SUBSTRATE. | 3C-LIKE PROTEASE, HYDROLASE-PEPTIDE COMPLEX
4zuh:B (SER10) to (LEU60) COMPLEX STRUCTURE OF PEDV 3CLPRO MUTANT (C144A) WITH A PEPTIDE SUBSTRATE. | 3C-LIKE PROTEASE, HYDROLASE-PEPTIDE COMPLEX
2hob:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE WITH AUTHENTIC N AND C- TERMINI IN COMPLEX WITH A MICHAEL ACCEPTOR N3 | SARS-COV, MAIN PROTEASE, MICHAEL ACCEPTOR N3, VIRAL PROTEIN
1uj1:A (GLY11) to (ARG60) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
1uj1:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
1uk2:A (GLY11) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) AT PH8.0 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
1uk2:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) AT PH8.0 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
1uk3:A (GLY11) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) AT PH7.6 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
1uk3:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) AT PH7.6 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
4mds:A (SER10) to (LYS61) DISCOVERY OF N-(BENZO[1,2,3]TRIAZOL-1-YL)-N-(BENZYL)ACETAMIDO)PHENYL) CARBOXAMIDES AS SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS (SARS- COV) 3CLPRO INHIBITORS: IDENTIFICATION OF ML300 AND NON-COVALENT NANOMOLAR INHIBITORS WITH AN INDUCED-FIT BINDING | CHYMOTRYPSIN-LIKE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5b6o:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF MS8104 | HYDROLASE, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
5b6o:B (SER10) to (ARG60) CRYSTAL STRUCTURE OF MS8104 | HYDROLASE, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
1wof:A (SER10) to (ARG60) CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR N1 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
1wof:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR N1 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
5c3n:A (GLY11) to (MET61) CRYSTAL STRUCTURE OF MERS CORONAVIRUS MAIN PROTEASE IN SPACEGROUP C2221 | MERS CORONAVIRUS, MAIN PROTEASE, 3CL PROTEASE, HYDROLASE
5c3n:B (SER10) to (ASP51) CRYSTAL STRUCTURE OF MERS CORONAVIRUS MAIN PROTEASE IN SPACEGROUP C2221 | MERS CORONAVIRUS, MAIN PROTEASE, 3CL PROTEASE, HYDROLASE
4nsy:A (HIS18) to (MET69) WILD-TYPE LYSOBACTER ENZYMOGENES LYSC ENDOPROTEINASE COVALENTLY INHIBITED BY TLCK | HYDROLASE, ENDOPROTEINASE, AROMATIC STACK, ATOMIC RESOLUTION, SERINE PROTEASE, CATALYTIC TRIAD, COVALENT INHIBITION, TLCK, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
5c5n:A (GLY11) to (LYS61) STRUCTURE OF SARS-3CL PROTEASE COMPLEX WITH A PHENYL-BETA-ALANYL (R, S)-N-DECALIN TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDRASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2yna:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF THE MAIN PROTEASE OF CORONAVIRUS HKU4 | HYDROLASE, SARS
2yna:B (SER10) to (SER60) CRYSTAL STRUCTURE OF THE MAIN PROTEASE OF CORONAVIRUS HKU4 | HYDROLASE, SARS
2ynb:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF THE MAIN PROTEASE OF CORONAVIRUS HKU4 IN COMPLEX WITH A MICHAEL ACCEPTOR SG85 | HYDROLASE, SARS, MICHAEL ACCEPTOR
2z3c:A (SER10) to (LYS61) A MECHANISTIC VIEW OF ENZYME INHIBITION AND PEPTIDE HYDROLYSIS IN THE ACTIVE SITE OF THE SARS-COV 3C-LIKE PEPTIDASE | BETA BARRELS, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2z3d:A (SER10) to (LYS61) A MECHANISTIC VIEW OF ENZYME INHIBITION AND PEPTIDE HYDROLYSIS IN THE ACTIVE SITE OF THE SARS-COV 3C-LIKE PEPTIDASE | BETA BARRELS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2z3e:A (GLY11) to (LYS61) A MECHANISTIC VIEW OF ENZYME INHIBITION AND PEPTIDE HYDROLYSIS IN THE ACTIVE SITE OF THE SARS-COV 3C-LIKE PEPTIDASE | SARS, 3C-LIKE PEPTIDASE, 3CL, MAIN PROTEINASE, VIRAL CYSTEINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, VIRAL PROTEIN
2z94:A (SER10) to (LYS61) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH TDT | COMPLEX, HYDROLASE
2z9g:A (SER10) to (LYS61) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH PMA | COMPLEX, ATP-BINDING, CYTOPLASM, ENDONUCLEASE, EXONUCLEASE, HELICASE, HYDROLASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RIBOSOMAL FRAMESHIFT, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
2z9j:A (SER10) to (ASN51) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH EPDTC | COMPLEX, ATP-BINDING, CYTOPLASM, ENDONUCLEASE, EXONUCLEASE, HELICASE, HYDROLASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RIBOSOMAL FRAMESHIFT, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
2z9j:B (SER10) to (ASN51) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH EPDTC | COMPLEX, ATP-BINDING, CYTOPLASM, ENDONUCLEASE, EXONUCLEASE, HELICASE, HYDROLASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RIBOSOMAL FRAMESHIFT, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
1lvo:A (SER10) to (VAL60) STRUCTURE OF CORONAVIRUS MAIN PROTEINASE REVEALS COMBINATION OF A CHYMOTRYPSIN FOLD WITH AN EXTRA ALPHA- HELICAL DOMAIN | 3C LIKE, CORONA, PROTEINASE, CHYMOTRYPSIN, CYSTEINE HISTIDINE DYAD, BETA BARREL, HYDROLASE
1lvo:B (SER10) to (VAL60) STRUCTURE OF CORONAVIRUS MAIN PROTEINASE REVEALS COMBINATION OF A CHYMOTRYPSIN FOLD WITH AN EXTRA ALPHA- HELICAL DOMAIN | 3C LIKE, CORONA, PROTEINASE, CHYMOTRYPSIN, CYSTEINE HISTIDINE DYAD, BETA BARREL, HYDROLASE
1lvo:C (SER10) to (VAL60) STRUCTURE OF CORONAVIRUS MAIN PROTEINASE REVEALS COMBINATION OF A CHYMOTRYPSIN FOLD WITH AN EXTRA ALPHA- HELICAL DOMAIN | 3C LIKE, CORONA, PROTEINASE, CHYMOTRYPSIN, CYSTEINE HISTIDINE DYAD, BETA BARREL, HYDROLASE
1lvo:D (SER10) to (VAL60) STRUCTURE OF CORONAVIRUS MAIN PROTEINASE REVEALS COMBINATION OF A CHYMOTRYPSIN FOLD WITH AN EXTRA ALPHA- HELICAL DOMAIN | 3C LIKE, CORONA, PROTEINASE, CHYMOTRYPSIN, CYSTEINE HISTIDINE DYAD, BETA BARREL, HYDROLASE
1lvo:E (SER10) to (VAL60) STRUCTURE OF CORONAVIRUS MAIN PROTEINASE REVEALS COMBINATION OF A CHYMOTRYPSIN FOLD WITH AN EXTRA ALPHA- HELICAL DOMAIN | 3C LIKE, CORONA, PROTEINASE, CHYMOTRYPSIN, CYSTEINE HISTIDINE DYAD, BETA BARREL, HYDROLASE
1lvo:F (SER10) to (SER59) STRUCTURE OF CORONAVIRUS MAIN PROTEINASE REVEALS COMBINATION OF A CHYMOTRYPSIN FOLD WITH AN EXTRA ALPHA- HELICAL DOMAIN | 3C LIKE, CORONA, PROTEINASE, CHYMOTRYPSIN, CYSTEINE HISTIDINE DYAD, BETA BARREL, HYDROLASE
2zu2:A (SER10) to (ILE59) COMPLEX STRUCTURE OF COV 229E 3CL PROTEASE WITH EPDTC | PROTEASE-INHIBITOR COMPLEX, HYDROLASE, METAL-BINDING, PROTEASE, THIOL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2zu2:B (SER10) to (ILE59) COMPLEX STRUCTURE OF COV 229E 3CL PROTEASE WITH EPDTC | PROTEASE-INHIBITOR COMPLEX, HYDROLASE, METAL-BINDING, PROTEASE, THIOL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2zu4:A (GLY11) to (LYS61) COMPLEX STRUCTURE OF SARS-COV 3CL PROTEASE WITH TG-0204998 | PROTEASE-INHIBITOR COMPLEX, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2zu5:A (SER10) to (LYS61) COMPLEX STRUCTURE OF SARS-COV 3CL PROTEASE WITH TG-0205486 | PROTEASE-INHIBITOR COMPLEX, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1z1i:A (GLY11) to (LYS61) CRYSTAL STRUCTURE OF NATIVE SARS CLPRO | HYDROLASE
3atw:A (SER10) to (LYS61) STRUCTURE-BASED DESIGN, SYNTHESIS, EVALUATION OF PEPTIDE-MIMETIC SARS 3CL PROTEASE INHIBITORS | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3atw:B (SER10) to (LYS61) STRUCTURE-BASED DESIGN, SYNTHESIS, EVALUATION OF PEPTIDE-MIMETIC SARS 3CL PROTEASE INHIBITORS | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3aw0:A (SER10) to (LYS61) STRUCTURE OF SARS 3CL PROTEASE WITH PEPTIDIC ALDEHYDE INHIBITOR | HYDROLASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3aw1:A (SER10) to (LYS61) STRUCTURE OF SARS 3CL PROTEASE AUTO-PROTEOLYSIS RESISTANT MUTANT IN THE ABSENT OF INHIBITOR | HYDROLASE PROTEINASE CONVERTING, HYDROLASE
3aw1:B (SER10) to (LYS61) STRUCTURE OF SARS 3CL PROTEASE AUTO-PROTEOLYSIS RESISTANT MUTANT IN THE ABSENT OF INHIBITOR | HYDROLASE PROTEINASE CONVERTING, HYDROLASE
2a5a:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF UNBOUND SARS CORONAVIRUS MAIN PEPTIDASE IN THE SPACE GROUP C2 | CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, LONG LOOP, ALPHA-HELICAL DOMAIN, DIMER, CATALYTIC DYAD, SPECIFICITY POCKETS, HYDROLASE
2a5i:A (SER10) to (ASN51) CRYSTAL STRUCTURES OF SARS CORONAVIRUS MAIN PEPTIDASE INHIBITED BY AN AZA-PEPTIDE EPOXIDE IN THE SPACE GROUP C2 | CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, LONG LOOP, ALPHA-HELICAL DOMAIN, DIMER, CATALYTIC DYAD, SPECIFICITY POCKETS, AZA-PEPTIDE EPOXIDE, SUBSTRATE-LIKE INHIBITOR, C-S COVALENT BOND, EPOXIDE STEREOCHEMISTRY, HYDROLASE
2a5k:A (SER10) to (LYS61) CRYSTAL STRUCTURES OF SARS CORONAVIRUS MAIN PEPTIDASE INHIBITED BY AN AZA-PEPTIDE EPOXIDE IN SPACE GROUP P212121 | CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, LONG LOOP, ALPHA-HELICAL DOMAIN, DIMER, CATALYTIC DYAD, SPECIFICITY POCKETS, AZA-PEPTIDE EPOXIDE, SUBSTRATE- LIKE INHIBITOR, C-S COVALENT BOND, EPOXIDE STEREOCHEMISTRY, HYDROLASE
2a5k:B (SER10) to (LYS61) CRYSTAL STRUCTURES OF SARS CORONAVIRUS MAIN PEPTIDASE INHIBITED BY AN AZA-PEPTIDE EPOXIDE IN SPACE GROUP P212121 | CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, LONG LOOP, ALPHA-HELICAL DOMAIN, DIMER, CATALYTIC DYAD, SPECIFICITY POCKETS, AZA-PEPTIDE EPOXIDE, SUBSTRATE- LIKE INHIBITOR, C-S COVALENT BOND, EPOXIDE STEREOCHEMISTRY, HYDROLASE
3m3s:A (GLY11) to (ARG60) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE ASN214ALA MUTANT WITH AUTHORIZE N-TERMINUS | SARS CORONAVIRUS PROTEASE N214A MUTATION, HYDROLASE
3m3s:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE ASN214ALA MUTANT WITH AUTHORIZE N-TERMINUS | SARS CORONAVIRUS PROTEASE N214A MUTATION, HYDROLASE
3m3v:A (SER10) to (LYS61) SARS-COV MAIN PROTEASE TRIPLE MUTANT STI/A WITH TWO N-TERMINAL ADDITIONAL RESIDUE (GLY-SER) | SARS PROTEASE STI/A MUTATION, HYDROLASE
3m3v:B (SER10) to (LYS61) SARS-COV MAIN PROTEASE TRIPLE MUTANT STI/A WITH TWO N-TERMINAL ADDITIONAL RESIDUE (GLY-SER) | SARS PROTEASE STI/A MUTATION, HYDROLASE
5eu8:A (SER10) to (VAL60) STRUCTURE OF FIPV MAIN PROTEASE IN COMPLEX WITH DUAL INHIBITORS | FIPV, MAIN PROTEASE, DUAL INHIBITORS, ZINC, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4rsp:A (SER10) to (MET61) X-RAY STRUCTURE OF MERS-COV NSP5 PROTEASE BOUND WITH A DESIGNED INHIBITOR | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3d62:A (SER10) to (ARG60) DEVELOPMENT OF BROAD-SPECTRUM HALOMETHYL KETONE INHIBITORS AGAINST CORONAVIRUS MAIN PROTEASE 3CLPRO | MAIN PROTEASE 3CLPRO, SARS, INHIBITOR, 95990, ATP-BINDING, ENDONUCLEASE, EXONUCLEASE, HELICASE, HYDROLASE, MEMBRANE, METAL- BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC-FINGER
4tww:A (SER10) to (ASN51) STRUCTURE OF SARS-3CL PROTEASE COMPLEX WITH A BROMOBENZOYL (S,R)-N- DECALIN TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDRASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4tww:B (SER10) to (ASN51) STRUCTURE OF SARS-3CL PROTEASE COMPLEX WITH A BROMOBENZOYL (S,R)-N- DECALIN TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDRASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4twy:A (SER10) to (LYS61) STRUCTURE OF SARS-3CL PROTEASE COMPLEX WITH A PHENYLBENZOYL (S,R)-N- DECALIN TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDRASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hyo:B (SER10) to (LEU60) X-RAY STRUCTURE OF UNBOUND PORCINE EPIDEMIC DIARRHEA VIRUS 3CLPRO | PEDV, 3CLPRO, CORONAVIRUS, MPRO, VIRAL PROTEIN
4f49:A (SER10) to (VAL60) 2.25A RESOLUTION STRUCTURE OF TRANSMISSIBLE GASTROENTERITIS VIRUS PROTEASE CONTAINING A COVALENTLY BOUND DIPEPTIDYL INHIBITOR | PROTEASE, ANTIVIRAL INHIBITORS, DIPEPTIDYL INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4f49:B (SER10) to (VAL60) 2.25A RESOLUTION STRUCTURE OF TRANSMISSIBLE GASTROENTERITIS VIRUS PROTEASE CONTAINING A COVALENTLY BOUND DIPEPTIDYL INHIBITOR | PROTEASE, ANTIVIRAL INHIBITORS, DIPEPTIDYL INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4f49:C (SER10) to (VAL60) 2.25A RESOLUTION STRUCTURE OF TRANSMISSIBLE GASTROENTERITIS VIRUS PROTEASE CONTAINING A COVALENTLY BOUND DIPEPTIDYL INHIBITOR | PROTEASE, ANTIVIRAL INHIBITORS, DIPEPTIDYL INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4f49:D (SER10) to (VAL60) 2.25A RESOLUTION STRUCTURE OF TRANSMISSIBLE GASTROENTERITIS VIRUS PROTEASE CONTAINING A COVALENTLY BOUND DIPEPTIDYL INHIBITOR | PROTEASE, ANTIVIRAL INHIBITORS, DIPEPTIDYL INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3ea7:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE TRIPLE MUTANT STI/A IN SPACE GROUP P21 | SARS-COV MAIN PROTEASE MUTANT, 3C-LIKE PROTEASE MUTANT, EXTRA HELICAL DOMAIN MUTATION, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC- FINGER
3ea7:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE TRIPLE MUTANT STI/A IN SPACE GROUP P21 | SARS-COV MAIN PROTEASE MUTANT, 3C-LIKE PROTEASE MUTANT, EXTRA HELICAL DOMAIN MUTATION, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC- FINGER
2amq:A (SER10) to (ARG60) CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N3 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
2amq:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N3 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
2bx4:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (P21212) | HYDROLASE, ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A- HELICES, VIRAL PROTEIN
3snd:A (GLY11) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AC- ESTLQ-H (COCRYSTALLIZATION) | 3C-LIKE PROTEINASE, PROTEASE, AC-ESTLQ-H, ACTIVE SITE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
2q6d:A (SER11) to (ALA58) CRYSTAL STRUCTURE OF INFECTIOUS BRONCHITIS VIRUS (IBV) MAIN PROTEASE | CORONAVIRUS; IBV; MAIN PROTEASE; 3C-LIKE PROTEINASE, HYDROLASE
2q6d:B (SER10) to (ALA58) CRYSTAL STRUCTURE OF INFECTIOUS BRONCHITIS VIRUS (IBV) MAIN PROTEASE | CORONAVIRUS; IBV; MAIN PROTEASE; 3C-LIKE PROTEINASE, HYDROLASE
2q6d:C (SER8) to (ALA58) CRYSTAL STRUCTURE OF INFECTIOUS BRONCHITIS VIRUS (IBV) MAIN PROTEASE | CORONAVIRUS; IBV; MAIN PROTEASE; 3C-LIKE PROTEINASE, HYDROLASE
3fzd:A (SER10) to (LYS61) MUTATION OF ASN28 DISRUPTS THE ENZYMATIC ACTIVITY AND DIMERIZATION OF SARS 3CLPRO | SARS, SARS 3CLPRO, PROTEASE, SARS-COV MPRO, DIMERIZATION, ANALYTICAL ULTRACENTRIFUGATION, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
1p9u:A (SER10) to (VAL60) CORONAVIRUS MAIN PROTEINASE (3CLPRO) STRUCTURE: BASIS FOR DESIGN OF ANTI-SARS DRUGS | SARS-COV, HCOV, TGEV, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1p9u:B (SER10) to (VAL60) CORONAVIRUS MAIN PROTEINASE (3CLPRO) STRUCTURE: BASIS FOR DESIGN OF ANTI-SARS DRUGS | SARS-COV, HCOV, TGEV, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1p9u:C (SER10) to (SER59) CORONAVIRUS MAIN PROTEINASE (3CLPRO) STRUCTURE: BASIS FOR DESIGN OF ANTI-SARS DRUGS | SARS-COV, HCOV, TGEV, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1p9u:D (SER10) to (VAL60) CORONAVIRUS MAIN PROTEINASE (3CLPRO) STRUCTURE: BASIS FOR DESIGN OF ANTI-SARS DRUGS | SARS-COV, HCOV, TGEV, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1p9u:E (SER10) to (VAL60) CORONAVIRUS MAIN PROTEINASE (3CLPRO) STRUCTURE: BASIS FOR DESIGN OF ANTI-SARS DRUGS | SARS-COV, HCOV, TGEV, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1p9u:F (SER10) to (VAL60) CORONAVIRUS MAIN PROTEINASE (3CLPRO) STRUCTURE: BASIS FOR DESIGN OF ANTI-SARS DRUGS | SARS-COV, HCOV, TGEV, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2duc:A (SER10) to (ARG60) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE(3CLPRO) | HYDROLASE, SARS CORONAVIRUS MAIN PROTEINASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2duc:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE(3CLPRO) | HYDROLASE, SARS CORONAVIRUS MAIN PROTEINASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
4yog:A (SER10) to (LYS61) HKU4-3CLPRO BOUND TO NON-COVALENT INHIBITOR 3B | HKU4 3CLPRO MPRO NSP5, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4yog:B (SER10) to (LYS61) HKU4-3CLPRO BOUND TO NON-COVALENT INHIBITOR 3B | HKU4 3CLPRO MPRO NSP5, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb3:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE IN APO FORM | HYDROLASE
4zro:A (SER10) to (VAL60) 2.1 A X-RAY STRUCTURE OF FIPV-3CLPRO BOUND TO COVALENT INHIBITOR | CORONAVIRUS, MAIN PROTEASE, 3CLPRO, MPRO, FIPV, FCOV, INHIBITOR COMPLEX, FELINE INFECTIOUS PERITONITIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4zro:B (SER10) to (VAL60) 2.1 A X-RAY STRUCTURE OF FIPV-3CLPRO BOUND TO COVALENT INHIBITOR | CORONAVIRUS, MAIN PROTEASE, 3CLPRO, MPRO, FIPV, FCOV, INHIBITOR COMPLEX, FELINE INFECTIOUS PERITONITIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4zro:C (SER10) to (SER59) 2.1 A X-RAY STRUCTURE OF FIPV-3CLPRO BOUND TO COVALENT INHIBITOR | CORONAVIRUS, MAIN PROTEASE, 3CLPRO, MPRO, FIPV, FCOV, INHIBITOR COMPLEX, FELINE INFECTIOUS PERITONITIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4zro:D (SER10) to (VAL60) 2.1 A X-RAY STRUCTURE OF FIPV-3CLPRO BOUND TO COVALENT INHIBITOR | CORONAVIRUS, MAIN PROTEASE, 3CLPRO, MPRO, FIPV, FCOV, INHIBITOR COMPLEX, FELINE INFECTIOUS PERITONITIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2gx4:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS 3CL PROTEASE INHIBITOR COMPLEX | SARS, 3CL PROTEASE, INHIBITOR COMPLEX, HYDROLASE
2h2z:A (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE WITH AUTHENTIC N AND C-TERMINI | SARS, MAIN PROTEASE, AUTHENTIC N AND C TERMINI, VIRAL PROTEIN
1uk4:B (SER10) to (LYS61) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) COMPLEXED WITH AN INHIBITOR | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, AN INHIBITOR, HYDROLASE
4nsv:A (HIS18) to (MET69) LYSOBACTER ENZYMOGENES LYSC ENDOPROTEINASE K30R MUTANT COVALENTLY INHIBITED BY TLCK | HYDROLASE, ENDOPROTEINASE, AROMATIC STACK, ATOMIC RESOLUTION, SERINE PROTEASE, CATALYTIC TRIAD, COVALENT INHIBITION, TLCK;, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4nsv:B (HIS18) to (MET69) LYSOBACTER ENZYMOGENES LYSC ENDOPROTEINASE K30R MUTANT COVALENTLY INHIBITED BY TLCK | HYDROLASE, ENDOPROTEINASE, AROMATIC STACK, ATOMIC RESOLUTION, SERINE PROTEASE, CATALYTIC TRIAD, COVALENT INHIBITION, TLCK;, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
5c5o:A (SER10) to (LYS61) STRUCTURE OF SARS-3CL PROTEASE COMPLEX WITH A PHENYL-BETA-ALANYL (S, R)-N-DECALIN TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDRASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5c5o:B (SER10) to (LYS61) STRUCTURE OF SARS-3CL PROTEASE COMPLEX WITH A PHENYL-BETA-ALANYL (S, R)-N-DECALIN TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDRASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2z9k:A (SER10) to (ARG60) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH JMF1600 | COMPLEX, ATP-BINDING, CYTOPLASM, ENDONUCLEASE, EXONUCLEASE, HELICASE, HYDROLASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RIBOSOMAL FRAMESHIFT, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
2z9k:B (SER10) to (ASN51) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH JMF1600 | COMPLEX, ATP-BINDING, CYTOPLASM, ENDONUCLEASE, EXONUCLEASE, HELICASE, HYDROLASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RIBOSOMAL FRAMESHIFT, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
2z9l:B (SER10) to (LYS61) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH JMF1586 | COMPLEX, HYDROLASE
3d23:A (THR10) to (VAL61) MAIN PROTEASE OF HCOV-HKU1 | MAIN PROTEASE, ATP-BINDING, ENDONUCLEASE, EXONUCLEASE, HELICASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC-FINGER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3d23:C (THR10) to (VAL61) MAIN PROTEASE OF HCOV-HKU1 | MAIN PROTEASE, ATP-BINDING, ENDONUCLEASE, EXONUCLEASE, HELICASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC-FINGER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3d23:D (THR10) to (VAL61) MAIN PROTEASE OF HCOV-HKU1 | MAIN PROTEASE, ATP-BINDING, ENDONUCLEASE, EXONUCLEASE, HELICASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC-FINGER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4gpg:A (ARG18) to (ILE69) X/N JOINT REFINEMENT OF ACHROMOBACTER LYTICUS PROTEASE I FREE FORM AT PD8.0 | LYSINE SPECIFIC SERINE PROTEASE, HYDROLASE