4grx:A (ALA353) to (LEU417) STRUCTURE OF AN OMEGA-AMINOTRANSFERASE FROM PARACOCCUS DENITRIFICANS | CLASS III TRANSAMINASE, TRANSFERASE
4waa:A (THR28) to (LEU98) CRYSTAL STRUCTURE OF NIX LIR-FUSED HUMAN LC3B_2-119 | AUTOPHAGY, SELECTIVE AUTOPHAGY, DEGRADATION, NIX, LC3, RECYCLING, LIR, STRUCTURAL PROTEIN
1a0o:B (GLY170) to (VAL228) CHEY-BINDING DOMAIN OF CHEA IN COMPLEX WITH CHEY | BACTERIAL CHEMOTAXIS, SIGNAL TRANSDUCTION, TWO-COMPONENT SYSTEM, HISTIDINE KINASE, RESPONSE REGULATOR
1a0o:D (GLU171) to (THR225) CHEY-BINDING DOMAIN OF CHEA IN COMPLEX WITH CHEY | BACTERIAL CHEMOTAXIS, SIGNAL TRANSDUCTION, TWO-COMPONENT SYSTEM, HISTIDINE KINASE, RESPONSE REGULATOR
2air:B (ILE25) to (ARG85) T-STATE ACTIVE SITE OF ASPARTATE TRANSCARBAMYLASE:CRYSTAL STRUCTURE OF THE CARBAMYL PHOSPHATE AND L-ALANOSINE LIGATED ENZYME | ASPARTATE TRANSCARBAMYLASE, ALANOSINE, CARBAMYL PHOSPHATE, T-STATE, TRANSFERASE
1nb4:A (THR287) to (TYR358) HC-J4 RNA POLYMERASE APO-FORM | HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE
1nb4:B (THR287) to (TYR358) HC-J4 RNA POLYMERASE APO-FORM | HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE
1nb6:A (THR287) to (TYR358) HC-J4 RNA POLYMERASE COMPLEXED WITH UTP | HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE
1nb6:B (THR287) to (TYR358) HC-J4 RNA POLYMERASE COMPLEXED WITH UTP | HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE
4gvl:D (LEU247) to (ARG311) CRYSTAL STRUCTURE OF THE GSUK RCK DOMAIN | MEMBRANE PROTEIN, ION CHANNEL, ADP BINDING, NAD BINDING, MEMBRANE, TRANSPORT PROTEIN
4gx2:C (LEU247) to (GLU310) GSUK CHANNEL BOUND TO NAD | MEMBRANE PROTEIN, ION CHANNEL, ADP BINDING, NAD BINDING, MEMBRANE, TRANSPORT PROTEIN
2oi2:A (SER233) to (SER291) STREPTOCOCCUS PNEUMONIAE MEVALONATE KINASE IN COMPLEX WITH DIPHOSPHOMEVALONATE | ENZYME-INHIBITOR COMPLEX, TRANSFERASE
4wim:A (LYS448) to (SER546) CRYSTAL STRUCTURE OF THE GMP SYNTHETASE FROM PLASMODIUM FALCIPARUM | GMP SYNTHETASE, PURINE SALVAGE PATHWAY, LYASE
1nhu:A (THR287) to (TYR358) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
1nhu:B (THR287) to (TYR358) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
1nhv:A (THR287) to (TYR358) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
1nhv:B (THR286) to (TYR358) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
3rrh:A (PHE769) to (GLY824) TERNARY STRUCTURE OF THE LARGE FRAGMENT OF TAQ DNA POLYMERASE BOUND TO AN ABASIC SITE AND A DDTTP | DNA POLYMERASE, ABASIC SITE, TRANSLESION SYNTHESIS, A-RULE, TRANSFERASE-DNA COMPLEX
1acm:B (ILE25) to (ILE86) ARGININE 54 IN THE ACTIVE SITE OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE IS CRITICAL FOR CATALYSIS: A SITE-SPECIFIC MUTAGENESIS, NMR AND X-RAY CRYSTALLOGRAPHY STUDY | TRANSFERASE (CARBAMOYL-P,ASPARTATE)
1acm:D (ILE25) to (ASN88) ARGININE 54 IN THE ACTIVE SITE OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE IS CRITICAL FOR CATALYSIS: A SITE-SPECIFIC MUTAGENESIS, NMR AND X-RAY CRYSTALLOGRAPHY STUDY | TRANSFERASE (CARBAMOYL-P,ASPARTATE)
3efr:A (SER13) to (TRP93) BIOTIN PROTEIN LIGASE R40G MUTANT FROM AQUIFEX AEOLICUS IN COMPLEX WITH BIOTIN | PROTEIN BIOTIN COMPLEX, LIGASE
3efr:B (SER13) to (TRP93) BIOTIN PROTEIN LIGASE R40G MUTANT FROM AQUIFEX AEOLICUS IN COMPLEX WITH BIOTIN | PROTEIN BIOTIN COMPLEX, LIGASE
2awz:A (THR286) to (TYR358) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5H) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
2awz:B (THR287) to (TYR358) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5H) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
2ax0:A (THR286) to (TYR358) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5X) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
2ax0:B (THR287) to (TYR358) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5X) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
2ax1:A (THR286) to (TYR358) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5EE) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
2ax1:B (THR286) to (TYR358) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5EE) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
1ahv:A (SER17) to (SER101) STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH 2-NITRO-P-CRESOL | FLAVOENZYME, OXIDASE, CATALYSIS
1ahv:B (SER17) to (SER101) STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH 2-NITRO-P-CRESOL | FLAVOENZYME, OXIDASE, CATALYSIS
1ahz:A (SER17) to (SER101) STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH 4-(1-HEPTENYL)PHENOL | FLAVOENZYME, OXIDASE, CATALYSIS
1ahz:B (SER17) to (SER101) STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH 4-(1-HEPTENYL)PHENOL | FLAVOENZYME, OXIDASE, CATALYSIS
1nmp:A (GLY107) to (THR160) STRUCTURAL GENOMICS, YBGI PROTEIN, UNKNOWN FUNCTION | YBGI, HYPOTHETICAL PROTEIN, TOROIDAL STRUCTURE, STRUCTURE 2 FUNCTION PROJECT, S2F, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
1nmp:C (GLY107) to (THR160) STRUCTURAL GENOMICS, YBGI PROTEIN, UNKNOWN FUNCTION | YBGI, HYPOTHETICAL PROTEIN, TOROIDAL STRUCTURE, STRUCTURE 2 FUNCTION PROJECT, S2F, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
2op5:B (SER35) to (VAL107) CRYSTAL STRUCTURE OF A DIMERIC FERREDOXIN-LIKE PROTEIN (JCVI_PEP_1096672785533) FROM UNCULTURED MARINE ORGANISM AT 2.20 A RESOLUTION | FERREDOXIN-LIKE PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, OXIDOREDUCTASE
2op5:E (ASP31) to (VAL107) CRYSTAL STRUCTURE OF A DIMERIC FERREDOXIN-LIKE PROTEIN (JCVI_PEP_1096672785533) FROM UNCULTURED MARINE ORGANISM AT 2.20 A RESOLUTION | FERREDOXIN-LIKE PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, OXIDOREDUCTASE
2op5:F (LEU30) to (VAL107) CRYSTAL STRUCTURE OF A DIMERIC FERREDOXIN-LIKE PROTEIN (JCVI_PEP_1096672785533) FROM UNCULTURED MARINE ORGANISM AT 2.20 A RESOLUTION | FERREDOXIN-LIKE PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, OXIDOREDUCTASE
1no5:B (LYS10) to (ASP82) STRUCTURE OF HI0073 FROM HAEMOPHILUS INFLUENZAE, THE NUCLEOTIDE BINDING DOMAIN OF THE HI0073/HI0074 TWO PROTEIN NUCLEOTIDYL TRANSFERASE. | HI0073, HI0074, STRUCTURAL GENOMICS, NUCLEOTIDYL TRANSFERASE, STRUCTURE 2 FUNCTION PROJECT, S2F, UNKNOWN FUNCTION
1nom:A (PRO151) to (SER229) DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF MNCL2 (5 MILLIMOLAR) | DNA-DIRECTED DNA POLYMERASE, DNA REPLICATION, DNA REPAIR, NUCLEOTIDYLTRANSFERASE
1np6:B (TYR58) to (GLY109) CRYSTAL STRUCTURE OF ESCHERICHIA COLI MOBB | MIXED ALPHA-BETA FOLD, ELONGATED BETA-SHEET, WALKER A MOTIF, P-LOOP STRUCTURAL MOTIF, BIOSYNTHETIC PROTEIN
2b43:A (SER328) to (GLU383) CRYSTAL STRUCTURE OF THE NORWALK VIRUS RNA DEPENDENT RNA POLYMERASE FROM STRAIN HU/NLV/DRESDEN174/1997/GE | RNA, POLYMERASE, VIRAL PROTEIN
2b43:B (SER328) to (GLU383) CRYSTAL STRUCTURE OF THE NORWALK VIRUS RNA DEPENDENT RNA POLYMERASE FROM STRAIN HU/NLV/DRESDEN174/1997/GE | RNA, POLYMERASE, VIRAL PROTEIN
2b43:C (SER328) to (GLU383) CRYSTAL STRUCTURE OF THE NORWALK VIRUS RNA DEPENDENT RNA POLYMERASE FROM STRAIN HU/NLV/DRESDEN174/1997/GE | RNA, POLYMERASE, VIRAL PROTEIN
2b43:D (SER328) to (GLU383) CRYSTAL STRUCTURE OF THE NORWALK VIRUS RNA DEPENDENT RNA POLYMERASE FROM STRAIN HU/NLV/DRESDEN174/1997/GE | RNA, POLYMERASE, VIRAL PROTEIN
4hac:A (LEU237) to (THR291) CRYSTAL STRUCTURE OF THE MEVALONATE KINASE FROM AN ARCHAEON METHANOSARCINA MAZEI | GHMP, ATP BINDING, PHOSPHORYLATION, TRANSFERASE
2b8k:B (PRO551) to (ARG617) 12-SUBUNIT RNA POLYMERASE II | DNA-DIRECTED RNA POLYMERASE, DNA-DEPENDENT RNA POLYMERASE, CELLULAR RNA POLYMERASE, METAL-BINDING, NUCLEAR PROTEIN, TRANSCRIPTION, TRANSFERASE
4wt9:A (THR287) to (TYR358) APO CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH E86Q E87Q S15G C223H V321I AND DELTA8 MUTATIONS | HCV, VIRAL, NS5B, RDRP, RESISTANCE MUTATION, DELTA8 BETA HAIRPIN LOOP DELETION, TRANSFERASE
4wto:D (ILE25) to (ASN88) NATURAL SOURCE ASPARTATE CARBAMOYLTRANSFERASE IN E.COIL (LIGAND-FREE AND ZINC-FREE) | NATURAL SOURCE, ATCASE, LIGAND-FREE, ZINC-FREE, TRANSFERASE
4wub:A (GLU183) to (THR245) N-TERMINAL 43 KDA FRAGMENT OF THE E. COLI DNA GYRASE B SUBUNIT GROWN FROM 100 MM KCL CONDITION | DNA GYRASE, ATPASE DOMAIN, ATPASE ACTIVITY, GHKL SUPERFAMILY, MONOVALENT CATIONS, ISOMERASE
4wud:A (GLU183) to (THR245) N-TERMINAL 43 KDA FRAGMENT OF THE E. COLI DNA GYRASE B SUBUNIT GROWN FROM NO SALT CONDITION | DNA GYRASE, ATPASE DOMAIN, ATPASE ACTIVITY, GHKL SUPERFAMILY, MONOVALENT CATIONS, ISOMERASE
2bak:A (SER61) to (GLU160) P38ALPHA MAP KINASE BOUND TO MPAQ | P38 MAP KINASE, SERINE/THREONINE KINASE, TRANSFERASE
4wxo:B (HIS373) to (VAL434) SADC (300-487) FROM PSEUDOMONAS AERUGINOSA PAO1 | GGDEF DOMAIN, DGC ACTIVITY, TRANSFERASE
3exc:X (ASP11) to (GLY68) STRUCTURE OF THE RNA'SE SSO8090 FROM SULFOLOBUS SOLFATARICUS | FERREDOXIN FOLD; DOUBLE SPLIT BETA-ALPHA-BETA FOLD, DIMER, CATALYTIC ASPARTATE, RNA'ASE, HYDROLASE, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, PSI-2
2pa3:A (GLY349) to (TYR410) CRYSTAL STRUCTURE OF SERINE BOUND G336V MUTANT OF E.COLI PHOSPHOGLYCERATE DEHYDROGENASE | OXIDOREDUCTASE, PHOSPHOGLYCERATE DEHYDROGENASE, SERINE BIOSYNTHESIS
3s3i:A (SER61) to (ASP150) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH SMALL MOLECULE INHIBITOR | P38 MAP KINASE, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3eyz:A (ILE796) to (GLY869) COCRYSTAL STRUCTURE OF BACILLUS FRAGMENT DNA POLYMERASE I WITH DUPLEX DNA (OPEN FORM) | PROTEIN-DNA COMPLEX, TRANSFERASE-DNA COMPLEX
2bjn:A (LEU64) to (VAL145) X-RAY STRUCTURE OF HUMAN TPC6 | TPC6, TRAPP COMPLEX, TETHERING, TRANSPORT PROTEIN
1bia:A (SER89) to (TRP173) THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA- BINDING DOMAINS | TRANSCRIPTION REGULATION
1bib:A (SER89) to (TRP173) THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA- BINDING DOMAINS | TRANSCRIPTION REGULATION
2bm0:A (PRO613) to (PHE673) RIBOSOMAL ELONGATION FACTOR G (EF-G) FUSIDIC ACID RESISTANT MUTANT T84A | SWITCH II, ELONGATION FACTOR, GTP-BINDING, TRANSLATION MUTATION THR84ALA, PROTEIN BIOSYNTHESIS
1o4u:A (ILE47) to (ALA122) CRYSTAL STRUCTURE OF A NICOTINATE NUCLEOTIDE PYROPHOSPHORYLASE (TM1645) FROM THERMOTOGA MARITIMA AT 2.50 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI, TRANSFERASE
1bpd:A (PRO151) to (SER229) CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA: EVIDENCE FOR A COMMON POLYMERASE MECHANISM | NUCLEOTIDYLTRANSFERASE
2bpg:A (ARG152) to (SER229) STRUCTURES OF TERNARY COMPLEXES OF RAT DNA POLYMERASE BETA, A DNA TEMPLATE-PRIMER, AND DDCTP | PROTEIN-DNA COMPLEX, TRANSFERASE/DNA COMPLEX
3s6h:Y (GLN80) to (ARG136) CRYSTAL STRUCTURE OF NATIVE MMNAGS/K | SYNTHASE AND KINASE, TRANSFERASE
2bq3:A (LYS78) to (SER145) DNA ADDUCT BYPASS POLYMERIZATION BY SULFOLOBUS SOLFATARICUS DPO4. ANALYSIS AND CRYSTAL STRUCTURES OF MULTIPLE BASE- PAIR SUBSTITUTION AND FRAMESHIFT PRODUCTS WITH THE ADDUCT 1,N2-ETHENOGUANINE | P2 DNA POLYMERASE IV, 1N2-ETHENOGUANINE ADDUCT, TRANSLESION DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSFERASE
2bqu:A (LYS78) to (SER145) DNA ADDUCT BYPASS POLYMERIZATION BY SULFOLOBUS SOLFATARICUS DPO4. ANALYSIS AND CRYSTAL STRUCTURES OF MULTIPLE BASE- PAIR SUBSTITUTION AND FRAMESHIFT PRODUCTS WITH THE ADDUCT 1,N2-ETHENOGUANINE | P2 DNA POLYMERASE IV, 1N2-ETHENOGUANINE ADDUCT, TRANSLESION DNA POLYMERASE, DDATP, NUCLEOTIDYLTRANSFERASE, TRANSFERASE
1oat:C (LEU352) to (HIS408) ORNITHINE AMINOTRANSFERASE | AMINOTRANSFERASE, PLP-DEPENDENT ENZYME, PYRIDOXAL PHOSPHATE
2pfl:B (GLY528) to (VAL603) CRYSTAL STRUCTURE OF PFL FROM E.COLI | GLYCYL RADICAL ENZYME, TRANSFERASE, GLUCOSE METABOLISM, LYASE
1bxn:A (ASP52) to (LEU138) THE CRYSTAL STRUCTURE OF RUBISCO FROM ALCALIGENES EUTROPHUS TO 2.7 ANGSTROMS. | LYASE (CARBON-CARBON), LYASE
1bxn:C (ASP52) to (LEU138) THE CRYSTAL STRUCTURE OF RUBISCO FROM ALCALIGENES EUTROPHUS TO 2.7 ANGSTROMS. | LYASE (CARBON-CARBON), LYASE
1bxn:E (ASP52) to (LEU138) THE CRYSTAL STRUCTURE OF RUBISCO FROM ALCALIGENES EUTROPHUS TO 2.7 ANGSTROMS. | LYASE (CARBON-CARBON), LYASE
1bxn:G (ASP52) to (LEU138) THE CRYSTAL STRUCTURE OF RUBISCO FROM ALCALIGENES EUTROPHUS TO 2.7 ANGSTROMS. | LYASE (CARBON-CARBON), LYASE
2bw7:B (GLN1029) to (GLN1122) A NOVEL MECHANISM FOR ADENYLYL CYCLASE INHIBITION FROM THE CRYSTAL STRUCTURE OF ITS COMPLEX WITH CATECHOL ESTROGEN | LYASE, ADENYLYL CYCLASE, CAMP SIGNALING, CATECHOL ESTROGEN, INHIBITOR COMPLEX, OXIDOREDUCTASE
3fds:A (LYS78) to (SER145) STRUCTURAL INSIGHT INTO RECRUITMENT OF TRANSLESION DNA POLYMERASE DPO4 TO SLIDING CLAMP PCNA | PROTEIN-PROTEIN COMPLEX, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE
1c2p:A (SER288) to (TYR358) HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE | POLYMERASE RNA-DEPENDENT RNA POLYMERASE HEPATITIS C VIRUS NS5B APOENZYME, TRANSFERASE
1c2p:B (THR287) to (TYR358) HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE | POLYMERASE RNA-DEPENDENT RNA POLYMERASE HEPATITIS C VIRUS NS5B APOENZYME, TRANSFERASE
4hyk:A (PRO79) to (ALA146) DBH TERNARY COMPLEX (SUBSTRATES PARTIALLY DISORDERED) | Y-FAMILY DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
2c0j:A (PHE71) to (PHE150) CRYSTAL STRUCTURE OF THE BET3-TRS33 HETERODIMER | TRANSPORT, TRANSPORT PROTEIN, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, LIPOPROTEIN, PALMITATE
3sfu:A (ASP331) to (GLN386) CRYSTAL STRUCTURE OF MURINE NOROVIRUS RNA DEPENDENT RNA POLYMERASE IN COMPLEX WITH RIBAVIRIN | RIGHT HANDED FOLD, VIRAL REPLICATION ENZYME, RNA BINDING, TRANSFERASE
3sfu:B (ASP331) to (GLN386) CRYSTAL STRUCTURE OF MURINE NOROVIRUS RNA DEPENDENT RNA POLYMERASE IN COMPLEX WITH RIBAVIRIN | RIGHT HANDED FOLD, VIRAL REPLICATION ENZYME, RNA BINDING, TRANSFERASE
3sfu:C (ASP331) to (GLN386) CRYSTAL STRUCTURE OF MURINE NOROVIRUS RNA DEPENDENT RNA POLYMERASE IN COMPLEX WITH RIBAVIRIN | RIGHT HANDED FOLD, VIRAL REPLICATION ENZYME, RNA BINDING, TRANSFERASE
4i28:A (ARG305) to (GLU386) BINARY COMPLEX OF MOUSE TDT WITH SSDNA AND ZN++ | TERMINAL TRANSFERASE, TRANSFERASE-DNA COMPLEX
4i2i:A (ARG305) to (ILE380) BINARY COMPLEX OF MOUSE TDT WITH AP5A | TERMINAL TRANSFERASE, TRANSFERASE
4i2j:A (ARG305) to (GLU386) BINARY COMPLEX OF MOUSE TDT WITH DCTP | TERMINAL TRANSFERASE, TRANSFERASE
2c22:A (GLU79) to (SER145) EFFICIENT AND HIGH FIDELITY INCORPORATION OF DCTP OPPOSITE 7,8-DIHYDRO-8-OXODEOXYGUANOSINE BY SULFOLOBUS SOLFATARICUS DNA POLYMERASE DPO4 | POLYMERASE, P2 DNA POLYMERASE IV, 7, 8-DIHYDRO-8-OXODEOXYGUANOSINE, TRANSLESION DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA- BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL - BINDING, MUTATOR PROTEIN
3fi4:A (SER61) to (GLU160) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH RO4499 | P38; MAP KINASE; SERINE/THREONINE KINASE, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, SIGNALING PROTEIN
2c2e:A (LYS78) to (SER145) EFFICIENT AND HIGH FIDELITY INCORPORATION OF DCTP OPPOSITE 7,8-DIHYDRO-8-OXODEOXYGUANOSINE BY SULFOLOBUS SOLFATARICUS DNA POLYMERASE DPO4 | POLYMERASE, P2 DNA POLYMERASE IV, 7, 8-DIHYDRO-8-OXODEOXYGUANOSINE, TRANSLESION DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA- BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, CALCIUM, METAL-BINDING, MUTATOR PROTEIN
2c2d:A (LYS78) to (SER145) EFFICIENT AND HIGH FIDELITY INCORPORATION OF DCTP OPPOSITE 7,8-DIHYDRO-8-OXODEOXYGUANOSINE BY SULFOLOBUS SOLFATARICUS DNA POLYMERASE DPO4 | POLYMERASE, P2 DNA POLYMERASE IV, 8-OXO-2P-DEOXY-GUANOSINE-5P- MONOPHOSPHATE, TRANSLESION DNA POLYMERASE, DATP, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, METAL-BINDING, MUTATOR PROTEIN, MAGNESIUM
2c2r:A (LYS78) to (SER145) EFFICIENT AND HIGH FIDELITY INCORPORATION OF DCTP OPPOSITE 7,8-DIHYDRO-8-OXODEOXYGUANOSINE BY SULFOLOBUS SOLFATARICUS DNA POLYMERASE DPO4 | POLYMERASE, P2 DNA POLYMERASE IV, 7, 8-DIHYDRO-8-OXODEOXYGUANOSINE, TRANSLESION DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA- BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, CALCIUM, METAL-BINDING, MUTATOR PROTEIN
1oj4:A (ARG220) to (VAL269) TERNARY COMPLEX OF 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE | TRANSFERASE, KINASE, ISOPRENOIDS BIOSYNTHESIS, GHMP KINASE SUPERFAMILY TRANSFERASE
1oj4:B (ARG220) to (VAL269) TERNARY COMPLEX OF 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE | TRANSFERASE, KINASE, ISOPRENOIDS BIOSYNTHESIS, GHMP KINASE SUPERFAMILY TRANSFERASE
3ska:A (THR286) to (TYR358) I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ska:B (SER288) to (TYR358) I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ske:A (THR286) to (TYR358) I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ske:B (THR286) to (TYR358) I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3fls:A (SER61) to (GLU160) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH 6-(2,4- DIFLUORO-PHENOXY)-2-((R)-2-METHANESULFONYL-1-METHYL- ETHYLAMINO)-8-METHYL-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE | P38; MAP KINASE; SERINE/THREONINE KINASE, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, SIGNALING PROTEIN
3skh:A (THR287) to (TYR358) I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3skh:B (SER288) to (TYR358) I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3fmj:A (SER61) to (GLU160) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH 4-(5-METHYL-3-PHENYL- ISOXAZOL-4-YL)-PYRIMIDIN-2-YLAMINE | P38; MAP KINASE; SERINE/THREONINE KINASE, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE, SIGNALING PROTEIN
2pwn:A (PHE71) to (PHE150) CRYSTAL STRUCTURE OF BET3 HOMOLOG (13277653) FROM MUS MUSCULUS AT 2.04 A RESOLUTION | 13277653, TRANSPORT PROTEIN PARTICLE (TRAPP) COMPONENT, BET3, BET3 HOMOLOG, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, TRANSPORT PROTEIN
1opi:A (ASP391) to (LYS462) SOLUTION STRUCTURE OF THE THIRD RNA RECOGNITION MOTIF (RRM) OF U2AF65 IN COMPLEX WITH AN N-TERMINAL SF1 PEPTIDE | NON-CANONICAL RNA RECOGNITION MOTIF, 4-STRANDED ANTI- PARALLEL BETA-SHEET, 2 ALPHA HELICES ADDITIONALLY EXTENDED BY A THIRD HELIX C, RNA BINDING PROTEIN
4i99:A (LYS1009) to (ASP1097) CRYSTAL STRUCTURE OF THE SMCHEAD BOUND TO THE C-WINGED HELIX DOMAIN OF SCPA | WINGED-HELIX DOMAIN AND SMC HEAD DOMAIN, CHROMOSOME CONDENSATION, SCPB, DNA BINDING PROTEIN
1cm5:A (GLY528) to (VAL603) CRYSTAL STRUCTURE OF C418A,C419A MUTANT OF PFL FROM E.COLI | GLYCYL RADICAL ENZYME, TRANSFERASE, GLUCOSE METABOLISM
1cm5:B (GLY528) to (VAL603) CRYSTAL STRUCTURE OF C418A,C419A MUTANT OF PFL FROM E.COLI | GLYCYL RADICAL ENZYME, TRANSFERASE, GLUCOSE METABOLISM
3fqk:A (THR286) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH HCV-796 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE, HCV-796
3fqk:B (THR286) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH HCV-796 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE, HCV-796
3fql:A (THR286) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B (CON1 1-570) WITH HCV-796 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE, HCV- 796
3frz:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE IN COMPLEX WITH PF868554 | VIRAL POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3fsf:A (SER61) to (GLU160) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH 3-(2,6- DICHLORO-PHENYL)-7-[4-(2-DIETHYLAMINO-ETHOXY)-PHENYLAMINO]- 1-METHYL-3,4-DIHYDRO-1H-PYRIMIDO[4,5-D]PYRIMIDIN-2-ONE | P38; MAP KINASE; SERINE/THREONINE KINASE, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, SIGNALING PROTEIN
1ouy:A (SER61) to (GLU160) THE STRUCTURE OF P38 ALPHA IN COMPLEX WITH A DIHYDROPYRIDO- PYRIMIDINE INHIBITOR | MAP KINASE, HYDROPHOBIC POCKET, KINASE DOMAIN, ATP BINDING DOMAIN, TRANSFERASE
4ic8:A (THR72) to (GLU170) CRYSTAL STRUCTURE OF THE APO ERK5 KINASE DOMAIN | KINASE, SIGNALING, TRANSFERASE
1csj:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE OF HEPATITIS C VIRUS | POLYPROTEIN, GLYCOPROTEIN, RNA-DIRECTED RNA POLYMERASE, CORE PROTEIN, COAT PROTEIN, ENVELOPE PROTEIN, HELICASE, ATP-BINDING, TRANSMEMBRANE, NONSTRUCTURAL PROTEIN, TRANSFERASE
1csj:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE OF HEPATITIS C VIRUS | POLYPROTEIN, GLYCOPROTEIN, RNA-DIRECTED RNA POLYMERASE, CORE PROTEIN, COAT PROTEIN, ENVELOPE PROTEIN, HELICASE, ATP-BINDING, TRANSMEMBRANE, NONSTRUCTURAL PROTEIN, TRANSFERASE
4ih5:A (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS | FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ih5:B (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS | FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ih6:A (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS | FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ih6:B (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS | FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ih7:B (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS | FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2cdq:B (GLY356) to (LYS418) CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA ASPARTATE KINASE COMPLEXED WITH LYSINE AND S-ADENOSYLMETHIONINE | ASPARTATE KINASE, AMINO ACID METABOLISM, ACT DOMAIN, ALLOSTERY, S-ADENOSYLMETHIONINE, LYSINE, ALLOSTERIC EFFECTOR, PLANT, TRANSFERASE, AMINO ACID BIOSYNTHESIS
2qd9:A (SER61) to (GLU160) P38 ALPHA MAP KINASE INHIBITOR BASED ON HETEROBICYCLIC SCAFFOLDS | SERINE/THREONINE-PROTEIN KINASE, KINASE, TRANSFERASE, P38 MAP KINASE
2cg8:A (ASP132) to (LEU215) THE BIFUNCTIONAL DIHYDRONEOPTERIN ALDOLASE 6-HYDROXYMETHYL- 7,8-DIHYDROPTERIN SYNTHASE FROM STREPTOCOCCUS PNEUMONIAE | LYASE/TRANSFERASE, ALDOLASE, FOLATE BIOSYNTHESIS, PYROPHOSPHOKINASE, LYASE, MULTIFUNCTIONAL ENZYME, TRANSFERASE
2cg8:B (ASP132) to (LEU215) THE BIFUNCTIONAL DIHYDRONEOPTERIN ALDOLASE 6-HYDROXYMETHYL- 7,8-DIHYDROPTERIN SYNTHASE FROM STREPTOCOCCUS PNEUMONIAE | LYASE/TRANSFERASE, ALDOLASE, FOLATE BIOSYNTHESIS, PYROPHOSPHOKINASE, LYASE, MULTIFUNCTIONAL ENZYME, TRANSFERASE
2qe2:A (THR287) to (TYR358) STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR | TRANSFERASE
2qe2:B (THR286) to (TYR358) STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR | TRANSFERASE
2qe5:A (THR286) to (TYR358) STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR | TRANSFERASE POLYMERASE
2qe5:B (THR286) to (TYR358) STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR | TRANSFERASE POLYMERASE
2qe5:C (THR286) to (TYR358) STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR | TRANSFERASE POLYMERASE
2qe5:D (THR286) to (TYR358) STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR | TRANSFERASE POLYMERASE
4xq8:B (ARG389) to (GLU465) HUMAN DNA POLYMERASE LAMBDA- MGDATP BINARY COMPLEX AND COMPLEX WITH 6 PAIRED DNA | COMPLEX, MGDATP, TRANSFERASE-DNA COMPLEX
3szy:A (VAL268) to (GLY330) CRYSTAL STRUCTURE OF PHOSPHONOACETATE HYDROLASE FROM SINORHIZOBIUM MELILOTI 1021 IN APO FORM | ALKALINE PHOSPHATASE SUPERFAMILY, HYDROLASE
3szz:A (VAL268) to (GLY330) CRYSTAL STRUCTURE OF PHOSPHONOACETATE HYDROLASE FROM SINORHIZOBIUM MELILOTI 1021 IN COMPLEX WITH ACETATE | ALKALINE PHOSPHATASE SUPERFAMILY, HYDROLASE
3t00:A (GLN269) to (GLY330) CRYSTAL STRUCTURE OF PHOSPHONOACETATE HYDROLASE FROM SINORHIZOBIUM MELILOTI 1021 IN COMPLEX WITH VANADATE | ALKALINE PHOSPHATASE SUPERFAMILY, TRANSITION STATE MIMIC, HYDROLASE
3t02:A (VAL268) to (GLY330) CRYSTAL STRUCTURE OF PHOSPHONOACETATE HYDROLASE FROM SINORHIZOBIUM MELILOTI 1021 IN COMPLEX WITH PHOSPHONOACETATE | ALKALINE PHOSPHATASE SUPERFAMILY, HYDROLASE
2qg9:B (ILE25) to (ASN88) STRUCTURE OF A REGULATORY SUBUNIT MUTANT D19A OF ATCASE FROM E. COLI | ALLOSTERIC ENZYME, REGULATORY CHAIN MUTANT, HETEROTROPIC REGULATION, TRANSFERASE/TRANSFERASE REGULATOR COMPLEX
4im3:A (ASP50) to (ILE145) STRUCTURE OF TANK-BINDING KINASE 1 | KINASE, SERINE/THREONINE KINASE, BX795, PCMNP, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3g86:A (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH THIAZINE INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3- BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3g86:B (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH THIAZINE INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3- BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
2cpi:A (ASP122) to (LEU190) SOLUTION STRUCTURE OF THE RNA RECOGNITION MOTIF OF CNOT4 | RNA RECOGNITION MOTIF, RRM, RNP, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, GENE REGULATION
3t2c:A (LYS24) to (PHE118) FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE/PHOSPHATASE FROM THERMOPROTEUS NEUTROPHILUS, DHAP-BOUND FORM | (BETA/ALPHA)8 TIM BARREL, FBP, F6P, DHAP, GAP, PHOSPHORYLATION, LYASE, HYDROLASE
3t2b:A (LYS24) to (PHE118) FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE/PHOSPHATASE FROM THERMOPROTEUS NEUTROPHILUS, LIGAND FREE | (BETA/ALPHA)8 TIM BARREL, FBP, F6P, DHAP, GAP, PHOSPHORYLATION, LYASE, HYDROLASE
3t2d:A (LYS24) to (PHE118) FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE/PHOSPHATASE FROM THERMOPROTEUS NEUTROPHILUS, FBP-BOUND FORM | (BETA/ALPHA)8 TIM BARREL, FBP, F6P, DHAP, GAP, PHOSPHORYLATION, LYASE, HYDROLASE
3t2e:A (LYS24) to (PHE118) FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE/PHOSPHATASE FROM THERMOPROTEUS NEUTROPHILUS, F6P-BOUND FORM | (BETA/ALPHA)8 TIM BARREL, FBP, F6P, DHAP, GAP, PHOSPHORYLATION, LYASE, HYDROLASE
3t2f:A (LYS24) to (PHE118) FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE/PHOSPHATASE FROM THERMOPROTEUS NEUTROPHILUS, SOAKED WITH EDTA AND DHAP | (BETA/ALPHA)8 TIM BARREL, FBP, F6P, DHAP, GAP, PHOSPHORYLATION, LYASE, HYDROLASE
1pil:A (LEU13) to (ASP95) STRUCTURE OF THE ESCHERICHIA COLI SIGNAL TRANSDUCING PROTEIN PII | NITROGEN REGULATORY PROTEIN
1dlo:B (LEU168) to (ASP237) HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 | NUCLEOTIDYLTRANSFERASE
4xtj:A (GLU183) to (THR245) N-TERMINAL 43 KDA FRAGMENT OF THE E. COLI DNA GYRASE B SUBUNIT GROWN FROM 100 MM KCL PLUS 100 MM NACL CONDITION | DNA GYRASE, ATPASE DOMAIN, ATPASE ACTIVITY, GHKL SUPERFAMILY, MONOVALENT CATIONS, ISOMERASE
3gc8:B (SER61) to (GLU160) THE STRUCTURE OF P38BETA C162S IN COMPLEX WITH A DIHYDROQUINAZOLINONE | SERINE/THRONINE KINASE, DRUG DESIGN, SELECTIVITY, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3gc9:A (SER61) to (GLU160) THE STRUCTURE OF P38BETA C119S, C162S IN COMPLEX WITH A DIHYDROQUINAZOLINONE INHIBITOR | SERINE/THREONINE KINASE, DRUG DESIGN, SELECTIVITY, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
4iqu:A (ARG305) to (GLU386) TDT CORE IN COMPLEX WITH INHIBITOR (2Z,5E)-6-[4-(4-FLUOROBENZOYL)-1H- PYRROL-2-YL]-2-HYDROXY-4-OXOHEXA-2,5-DIENOIC ACID | TERMINAL TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3gcp:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH SB203580 | DFG-OUT, TYPE I, SB203580, ALTERNATIVE SPLICING, ATP- BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3gcs:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH SORAFENIB | DFG-OUT, TYPE II, BAY439006, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
4xul:A (TYR23) to (CYS101) CRYSTAL STRUCTURE OF M. CHILENSIS MG662 PROTEIN COMPLEXED WITH GTP | NUCLEOTIDYL TRANSFERASE, GTP COMPLEX, ORFAN, TRANSFERASE
4xv2:B (GLU501) to (GLU586) B-RAF KINASE V600E ONCOGENIC MUTANT IN COMPLEX WITH DABRAFENIB | B-RAF, BRAF, PROTO-ONCOGENE, V600E, KINASE, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4xvl:A (GLN753) to (GLY849) BINARY COMPLEX OF HUMAN POLYMERASE NU AND DNA WITH THE FINGER DOMAIN OPEN | POL NU, POLYMERASE, ERROR-PRONE DNA SYNTHESIS, TRANSFERASE-DNA COMPLEX
4xvk:A (GLN753) to (GLY849) BINARY COMPLEX OF HUMAN POLYMERASE NU AND DNA WITH THE FINGER DOMAIN CLOSED | POL NU, POLYMERASE, ERROR-PRONE DNA SYNTHESIS, TRANSFERASE-DNA COMPLEX
3t53:A (THR66) to (LEU129) CRYSTAL STRUCTURES OF THE EXTRUSION STATE OF THE CUSBA ADAPTOR- TRANSPORTER COMPLEX | TRANSMEMBRANE HELIX, HEAVY METAL EFFLUX, TRANSPORT PROTEIN
3t5h:A (GLU79) to (SER145) TERNARY COMPLEX OF HNE ADDUCT MODIFIED DNA (5'-CXG-3' VS 13-MER) WITH DPO4 AND INCOMING DDGT | TERNARY COMPLEX OF DPO4-DNA-DGTP, DNA POLYMERASE, HNE, DNA- TRANSFERASE COMPLEX
3t5j:A (GLU79) to (SER145) TERNARY COMPLEX OF HNE ADDUCT MODIFIED DNA (5'-TXG-3' VS 13-MER) WITH DPO4 AND INCOMING DDTP | TERNARY COMPLEX OF DPO4-DNA-DATP, DNA POLYMERASE, HNE, DNA- TRANSFERASE COMPLEX
3t5k:A (GLU79) to (SER145) TERNARY COMPLEX OF HNE ADDUCT MODIFIED DNA (5'-TXG-3' VS 14-MER) WITH DPO4 AND INCOMING DDTP | TERNARY COMPLEX OF DPO4-DNA-DATP, DNA POLYMERASE, HNE, DNA- TRANSFERASE COMPLEX
3t5l:A (GLU79) to (SER145) TERNARY COMPLEX OF HNE ADDUCT MODIFIED DNA (5'-CXG-3' VS 14-MER) WITH DPO4 AND INCOMING DDGT | TERNARY COMPLEX OF DPO4-DNA-DGTP, DNA POLYMERASE, HNE, DNA- TRANSFERASE COMPLEX
4xyc:F (VAL192) to (PHE258) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
4xyc:H (ASP193) to (PHE258) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
4xyc:K (ASP193) to (PHE258) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
4xyc:M (VAL192) to (PHE258) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
4xyc:N (VAL192) to (PHE258) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
4xyc:P (ASP193) to (PHE258) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
4xyc:Q (VAL192) to (PHE258) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
4xyc:S (VAL192) to (PHE258) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
4xyc:T (ASP193) to (PHE258) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
4xyc:V (VAL192) to (PHE258) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
4xyc:W (VAL192) to (PHE258) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
4xyc:X (VAL192) to (PHE258) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
2cwx:A (PRO62) to (LEU120) CRYSTAL STRUCTURE OF OCTAMERIC RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE/OXYGENASE (RUBISCO) FROM PYROCOCCUS HORIKOSHII OT3 (FORM- 1 CRYSTAL) | LYASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
3gii:A (LYS78) to (SER145) DPO4 EXTENSION TERNARY COMPLEX WITH DISORDERED A OPPOSITE AN OXOG IN ANTI CONFORMATION | DNA POLYMERASE, 8-OXOGUANINE, Y-FAMILY, LESION BYPASS, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
4iwg:B (GLY112) to (LYS165) CRYSTAL STRUCTURE OF THE CONSERVED HYPOTHETICAL PROTEIN MJ0927 FROM METHANOCALDOCOCCUS JANNASCHII (IN C2221 FORM) | NIF3-LIKE, UNKNOWN FUNCTION
3gik:A (LYS78) to (SER145) DPO4 EXTENSION TERNARY COMPLEX WITH THE OXOG(ANTI)-C(ANTI) PAIR | DNA POLYMERASE, 8-OXOGUANINE, Y-FAMILY, LESION BYPASS, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3gil:A (LYS78) to (SER145) DPO4 EXTENSION TERNARY COMPLEX WITH OXOG(ANTI)-T(ANTI) PAIR | DNA POLYMERASE, 8-OXOGUANINE, Y-FAMILY, LESION BYPASS, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3gil:B (LYS1078) to (SER1145) DPO4 EXTENSION TERNARY COMPLEX WITH OXOG(ANTI)-T(ANTI) PAIR | DNA POLYMERASE, 8-OXOGUANINE, Y-FAMILY, LESION BYPASS, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3gim:A (LYS78) to (SER145) DPO4 EXTENSION TERNARY COMPLEX WITH OXOG(ANTI)-G(SYN) PAIR | DNA POLYMERASE, 8-OXOGUANINE, Y-FAMILY, LESION BYPASS, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
4iwm:A (GLY112) to (LYS165) CRYSTAL STRUCTURE OF THE CONSERVED HYPOTHETICAL PROTEIN MJ0927 FROM METHANOCALDOCOCCUS JANNASCHII (IN P21 FORM) | NIF3-LIKE, UNKNOWN FUNCTION
4iwm:C (GLY112) to (LYS165) CRYSTAL STRUCTURE OF THE CONSERVED HYPOTHETICAL PROTEIN MJ0927 FROM METHANOCALDOCOCCUS JANNASCHII (IN P21 FORM) | NIF3-LIKE, UNKNOWN FUNCTION
4iwm:D (GLY112) to (LYS165) CRYSTAL STRUCTURE OF THE CONSERVED HYPOTHETICAL PROTEIN MJ0927 FROM METHANOCALDOCOCCUS JANNASCHII (IN P21 FORM) | NIF3-LIKE, UNKNOWN FUNCTION
4iwm:E (GLY112) to (LYS165) CRYSTAL STRUCTURE OF THE CONSERVED HYPOTHETICAL PROTEIN MJ0927 FROM METHANOCALDOCOCCUS JANNASCHII (IN P21 FORM) | NIF3-LIKE, UNKNOWN FUNCTION
4iwm:F (GLY112) to (SER164) CRYSTAL STRUCTURE OF THE CONSERVED HYPOTHETICAL PROTEIN MJ0927 FROM METHANOCALDOCOCCUS JANNASCHII (IN P21 FORM) | NIF3-LIKE, UNKNOWN FUNCTION
4iwp:A (PRO48) to (ILE145) CRYSTAL STRUCTURE AND MECHANISM OF ACTIVATION OF TBK1 | KINASE, ATP BINDING, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2cz4:C (GLU18) to (VAL88) CRYSTAL STRUCTURE OF A PUTATIVE PII-LIKE SIGNALING PROTEIN (TTHA0516) FROM THERMUS THERMOPHILUS HB8 | CONSERVED HYPOTHETICAL PROTEIN, PII-LIKE SIGNALING PROTEIN, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, UNKNOWN FUNCTION
2cz9:A (CYS280) to (ILE341) CRYSTAL STRUCTURE OF GALACTOKINASE FROM PYROCOCCUS HORIKOSHI | GALACTOKINASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
2qv6:B (SER151) to (GLY219) GTP CYCLOHYDROLASE III FROM M. JANNASCHII (MJ0145) COMPLEXED WITH GTP AND METAL IONS | ENZYME, GTP, FAPY, HYDROLASE
2qv6:D (SER151) to (GLY219) GTP CYCLOHYDROLASE III FROM M. JANNASCHII (MJ0145) COMPLEXED WITH GTP AND METAL IONS | ENZYME, GTP, FAPY, HYDROLASE
4iz0:A (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2,4,5- TRICHLORO-N-(5-METHYL-1,2-OXAZOL-3-YL)BENZENESULFONAMIDE | HCV NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4iz0:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2,4,5- TRICHLORO-N-(5-METHYL-1,2-OXAZOL-3-YL)BENZENESULFONAMIDE | HCV NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1dzn:A (SER17) to (SER101) ASP170SER MUTANT OF VANILLYL-ALCOHOL OXIDASE | FLAVIN-DEPENDENT OXIDASE ENZYME, FLAVIN-DEPENDENT OXIDASE
4j02:A (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH [(1R)-5,8- DICHLORO-1-PROPYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOL-1-YL]ACETIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j02:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH [(1R)-5,8- DICHLORO-1-PROPYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOL-1-YL]ACETIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j04:A (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 4-CHLORO-2- {[(2,4,5-TRICHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j04:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 4-CHLORO-2- {[(2,4,5-TRICHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j06:A (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(5- BROMOTHIOPHEN-2-YL)SULFONYL]AMINO}-4-CHLOROBENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j06:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(5- BROMOTHIOPHEN-2-YL)SULFONYL]AMINO}-4-CHLOROBENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j08:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(4- METHYLPHENYL)SULFONYL]AMINO}-5-PHENOXYBENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j08:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(4- METHYLPHENYL)SULFONYL]AMINO}-5-PHENOXYBENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j0a:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(4- METHYLPHENYL)SULFONYL]AMINO}-4-PHENOXYBENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j0a:B (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(4- METHYLPHENYL)SULFONYL]AMINO}-4-PHENOXYBENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3gnv:A (THR287) to (TYR358) HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 1B | HEPATITIS C VIRUS, 1.5-BENZODIAZEPINE, NS5B, SULFONE, POLYMERASE, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3gnv:B (THR286) to (TYR358) HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 1B | HEPATITIS C VIRUS, 1.5-BENZODIAZEPINE, NS5B, SULFONE, POLYMERASE, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
2d3u:A (THR287) to (TYR358) X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C VIRUS, RNA-DEPENDENT RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
2d3u:B (THR287) to (TYR358) X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C VIRUS, RNA-DEPENDENT RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
3gnw:A (THR287) to (TYR358) HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 4C | 1,5-BENZODIAZEPINES, HEPATITIS C VIRUS, NS5B, POLYMERASE, SULFONE, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3gnw:B (THR287) to (TYR358) HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 4C | 1,5-BENZODIAZEPINES, HEPATITIS C VIRUS, NS5B, POLYMERASE, SULFONE, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
2d3z:A (THR286) to (TYR358) X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C VIRUS, RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
2d3z:B (THR287) to (TYR358) X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C VIRUS, RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
2d7s:A (ALA302) to (PRO366) FOOT AND MOUTH DISEASE VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH VPG PROTEIN | FOOT AND MOUTH DISEASE VIRUS, RNA-DEPENDENT RNA POLYMERASE, 3D POLYMERASE, VPG, PROTEIN-PRIMER, TRANSFERASE
3gqc:D (PHE543) to (GLY611) STRUCTURE OF HUMAN REV1-DNA-DNTP TERNARY COMPLEX | PROTEIN-DNA COMPLEX, DNA DAMAGE, DNA REPAIR, DNA SYNTHESIS, DNA- BINDING, MAGNESIUM, METAL-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, TRANSFERASE, TRANSFERASE-DNA COMPLEX
2r3v:A (HIS312) to (GLU369) THE BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACK INHIBITION OF MEVALONATE KINASE AND ISOPRENOID METABOLISM | MEVALONATE KINASE, FARNESYL THIODIPHOPHATE, ATP-BINDING, CATARACT, CHOLESTEROL BIOSYNTHESIS, CYTOPLASM, DISEASE MUTATION, LIPID SYNTHESIS, NUCLEOTIDE-BINDING, PEROXISOME, POLYMORPHISM, STEROID BIOSYNTHESIS, STEROL BIOSYNTHESIS, TRANSFERASE
2r3v:B (HIS312) to (GLU369) THE BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACK INHIBITION OF MEVALONATE KINASE AND ISOPRENOID METABOLISM | MEVALONATE KINASE, FARNESYL THIODIPHOPHATE, ATP-BINDING, CATARACT, CHOLESTEROL BIOSYNTHESIS, CYTOPLASM, DISEASE MUTATION, LIPID SYNTHESIS, NUCLEOTIDE-BINDING, PEROXISOME, POLYMORPHISM, STEROID BIOSYNTHESIS, STEROL BIOSYNTHESIS, TRANSFERASE
3gsz:B (THR286) to (TYR358) STRUCTURE OF THE GENOTYPE 2B HCV POLYMERASE | POLYMERASE, HCV, TRANSFERASE
2dej:A (CYS280) to (ILE341) CRYSTAL STRUCTURE OF GALAKTOKINASE FROM PYROCOCCUS HORIKOSHII WITH AMP-PN AND GALACTOSE | GALACTOKINASE, ADP ANALOGUE, GALACTOSE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
3gtg:B (MET552) to (ASP618) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 12MER RNA | TRANSCRIPTION, TRANSFERASE/DNA-RNA HYBRID, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, TRANSFERASE/DNA/RNA HYBRID COMPLEX
4y7i:B (LEU173) to (VAL239) CRYSTAL STRUCTURE OF MTMR8 | MTMR8, MYOTUBULARIN RELATED PROTEIN, PHOSPHOINOSITID, PHOSPHATASE
3tfu:B (LEU356) to (ARG403) CRYSTAL STRUCTURE OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE (BIOA) FROM MYCOBACTERIUM TUBERCULOSIS, POST-REACTION COMPLEX WITH A 3,6- DIHYDROPYRID-2-ONE HETEROCYCLE INHIBITOR | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2r7o:A (GLN595) to (SER671) CRYSTAL STRUCTURE OF VP1 APOENZYME OF ROTAVIRUS SA11 (N- TERMINAL HEXAHISTIDINE-TAGGED) | VIRAL PROTEIN, RNA-DEPENDENT RNA POLYMERASE, SINGLE SUBUNIT POLYMERASE FOLD, FINGERS, PALM, THUMB, RIGHT HAND CONFIGURATION, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE
2r7q:A (GLN595) to (SER671) CRYSTAL STRUCTURE OF VP1 APOENZYME OF ROTAVIRUS SA11 (C- TERMINAL HEXAHISTIDINE-TAGGED) | VIRAL PROTEIN, RNA-DEPENDENT RNA POLYMERASE, SINGLE SUBUNIT POLYMERASE FOLD, FINGERS, PALM, THUMB, RIGHT HAND CONFIGURATION, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE
2r7s:A (LYS597) to (SER671) CRYSTAL STRUCTURE OF ROTAVIRUS SA11 VP1 / RNA (UGUGCC) COMPLEX | VIRAL PROTEIN, RNA-DEPENDENT RNA POLYMERASE, SINGLE SUBUNIT POLYMERASE FOLD, FINGERS, PALM, THUMB, RIGHT HAND CONFIGURATION, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE-RNA COMPLEX
2r7t:A (THR596) to (SER671) CRYSTAL STRUCTURE OF ROTAVIRUS SA11 VP1/RNA (UGUGAACC) COMPLEX | VIRAL PROTEIN, RNA-DEPENDENT RNA POLYMERASE, SINGLE SUBUNIT POLYMERASE FOLD, FINGERS, PALM, THUMB, RIGHT HAND CONFIGURATION, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE-RNA COMPLEX
2r7u:A (LYS597) to (SER671) CRYSTAL STRUCTURE OF ROTAVIRUS SA11 VP1/RNA (AAAAGCC) COMPLEX | VIRAL PROTEIN, RNA-DEPENDENT RNA POLYMERASE, SINGLE SUBUNIT POLYMERASE FOLD, FINGERS, PALM, THUMB, RIGHT HAND CONFIGURATION, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE-RNA COMPLEX
2r7v:A (THR596) to (SER671) CRYSTAL STRUCTURE OF ROTAVIRUS SA11 VP1/RNA (GGCUUU) COMPLEX | VIRAL PROTEIN, RNA-DEPENDENT RNA POLYMERASE, SINGLE SUBUNIT POLYMERASE FOLD, FINGERS, PALM, THUMB, RIGHT HAND CONFIGURATION, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE-RNA COMPLEX
2r7w:A (LYS597) to (SER671) CRYSTAL STRUCTURE OF ROTAVIRUS SA11 VP1/RNA (UGUGACC)/MRNA 5'-CAP (M7GPPPG) COMPLEX | VIRAL PROTEIN, RNA-DEPENDENT RNA POLYMERASE, SINGLE SUBUNIT POLYMERASE FOLD, FINGERS, PALM, THUMB, RIGHT HAND CONFIGURATION, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE-RNA COMPLEX
2r7x:A (LYS597) to (SER671) CRYSTAL STRUCTURE OF ROTAVIRUS SA11 VP1/RNA (UGUGACC)/GTP COMPLEX | VIRAL PROTEIN, RNA-DEPENDENT RNA POLYMERASE, SINGLE SUBUNIT POLYMERASE FOLD, FINGERS, PALM, THUMB, RIGHT HAND CONFIGURATION, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE-RNA COMPLEX
2r7x:B (THR596) to (SER671) CRYSTAL STRUCTURE OF ROTAVIRUS SA11 VP1/RNA (UGUGACC)/GTP COMPLEX | VIRAL PROTEIN, RNA-DEPENDENT RNA POLYMERASE, SINGLE SUBUNIT POLYMERASE FOLD, FINGERS, PALM, THUMB, RIGHT HAND CONFIGURATION, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE-RNA COMPLEX
3gtp:B (MET552) to (ASP618) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 24MER RNA | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA- DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, TRANSFERASE/DNA-RNA HYBRID COMPLEX
2r8h:A (LYS78) to (SER145) SELECTIVITY OF NUCLEOSIDE TRIPHOSPHATE INCORPORATION OPPOSITE 1,N2- PROPANODEOXYGUANOSINE (PDG) BY THE SULFOLOBUS SOLFATARICUS DNA POLYMERASE DPO4 POLYMERASE | EXOCYCLIC ADDUCTS, REPLICATION BYPASS, TRANSLESION, POLYMERASE, FRAMESHIFTING, REPLICATION, TRANSFERASE-DNA COMPLEX
2r8g:A (LYS78) to (SER145) SELECTIVITY OF NUCLEOSIDE TRIPHOSPHATE INCORPORATION OPPOSITE 1,N2-PROPANODEOXYGUANOSINE (PDG) BY THE SULFOLOBUS SOLFATARICUS DNA POLYMERASE DPO4 POLYMERASE | EXOCYCLIC ADDUCTS, REPLICATION BYPASS, CRYSTALLOGRAPHY, TRANSLESION, POLYMERASE, FRAMESHIFTING, REPLICATION, TRANSFERASE/DNA COMPLEX
2r8i:A (LYS78) to (SER145) SELECTIVITY OF NUCLEOSIDE TRIPHOSPHATE INCORPORATION OPPOSITE 1,N2-PROPANODEOXYGUANOSINE (PDG) BY THE SULFOLOBUS SOLFATARICUS DNA POLYMERASE DPO4 POLYMERASE | EXOCYCLIC ADDUCTS, REPLICATION BYPASS, CRYSTALLOGRAPHY, TRANSLESION, POLYMERASE, FRAMESHIFTING, REPLICATION, TRANSFERASE/DNA COMPLEX
1q8i:A (ASP512) to (ARG600) CRYSTAL STRUCTURE OF ESCHERICHIA COLI DNA POLYMERASE II | DNA POLYMERASE II, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, TRANSFERASE
1q95:H (ILE25) to (ASN88) ASPARTATE TRANSCARBAMYLASE (ATCASE) OF ESCHERICHIA COLI: A NEW CRYSTALLINE R STATE BOUND TO PALA, OR TO PRODUCT ANALOGUES PHOSPHATE AND CITRATE | ASPARTATE TRANSCARBAMYLASE, ASPARTATE CARBAMOYLTRANSFERASE, N-CARBAMYL-L-ASPARTATE, PALA, ATCASE-PALA COMPLEX, R STATE
2drd:B (THR600) to (PHE666) CRYSTAL STRUCTURE OF A MULTIDRUG TRANSPORTER REVEAL A FUNCTIONALLY ROTATING MECHANISM | MEMBRANE TRANSPORTER, MEMBRANE PROTEIN, MULTIDRUG EFFLUX, DRUG RESISTANCE, TRANSPORTER, EXPORTER, ANTIPORTER
3gyn:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL MONOCYCLIC DIHYDROPYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION REGULATION, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3gyn:B (VAL284) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL MONOCYCLIC DIHYDROPYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION REGULATION, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
1ei1:A (GLU185) to (THR245) DIMERIZATION OF E. COLI DNA GYRASE B PROVIDES A STRUCTURAL MECHANISM FOR ACTIVATING THE ATPASE CATALYTIC CENTER | ATPASE DOMAIN, DIMER, ISOMERASE
1ei1:B (GLU583) to (THR645) DIMERIZATION OF E. COLI DNA GYRASE B PROVIDES A STRUCTURAL MECHANISM FOR ACTIVATING THE ATPASE CATALYTIC CENTER | ATPASE DOMAIN, DIMER, ISOMERASE
1ei6:A (LEU259) to (THR321) CRYSTAL STRUCTURE OF PHOSPHONOACETATE HYDROLASE COMPLEXED WITH PHOSPHONOFORMATE | PHOSPHONOACETATE, HYDROLASE, ZINC, CRYSTAL STRUCTURE
1ei6:B (LEU259) to (THR321) CRYSTAL STRUCTURE OF PHOSPHONOACETATE HYDROLASE COMPLEXED WITH PHOSPHONOFORMATE | PHOSPHONOACETATE, HYDROLASE, ZINC, CRYSTAL STRUCTURE
1ei6:D (LEU259) to (THR321) CRYSTAL STRUCTURE OF PHOSPHONOACETATE HYDROLASE COMPLEXED WITH PHOSPHONOFORMATE | PHOSPHONOACETATE, HYDROLASE, ZINC, CRYSTAL STRUCTURE
3tp2:B (LYS152) to (TRP225) CRYSTAL STRUCTURE OF THE SPLICING FACTOR CWC2 FROM YEAST | RNA SCAFFOLD, TORUS DOMAIN, CCCH ZINC FINGER, RRM DOMAIN, SPLICING
2rd5:B (GLY76) to (SER135) STRUCTURAL BASIS FOR THE REGULATION OF N-ACETYLGLUTAMATE KINASE BY PII IN ARABIDOPSIS THALIANA | PROTEIN-PROTEIN COMPLEX, REGULATION OF ARGININE BIOSYNTHESIS, NITROGEN METABOLISM, KINASE, TRANSFERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, PROTEIN BINDING
2rdi:A (LYS78) to (SER145) SNAPSHOTS OF A Y-FAMILY DNA POLYMERASE IN REPLICATION: DPO4 IN APO AND BINARY/TERNARY COMPLEX FORMS | DNA POLYMERASE, APO-ENZYME, Y-FAMILY, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE
2rdj:A (LYS78) to (SER145) SNAPSHOTS OF A Y-FAMILY DNA POLYMERASE IN REPLICATION: DPO4 IN APO AND BINARY/TERNARY COMPLEX FORMS | DNA POLYMERASE, DNA-ENZYME COMPLEX, Y-FAMILY, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
2rdj:B (LYS78) to (SER145) SNAPSHOTS OF A Y-FAMILY DNA POLYMERASE IN REPLICATION: DPO4 IN APO AND BINARY/TERNARY COMPLEX FORMS | DNA POLYMERASE, DNA-ENZYME COMPLEX, Y-FAMILY, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
4ycx:A (LEU291) to (SER368) BINARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH 2-NT GAPPED DNA SUBSTRATE | POLYMERASE, DNA REPAIR, NHEJ, TRANSFERASE-DNA COMPLEX
4jjs:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 2 | LAVAL, HCV VIRUS RDRP NS5B POLYMERASE, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4jjs:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 2 | LAVAL, HCV VIRUS RDRP NS5B POLYMERASE, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4yd1:A (LEU291) to (GLN366) TERNARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH 2-NT GAPPED DNA SUBSTRATE AND AN INCOMING NONHYDROLYZABLE DUMPNPP | POLYMERASE, DNA REPAIR, NHEJ, TRANSFERASE-DNA COMPLEX
4jju:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 29 | VIRUS RDRP NS5B POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jju:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 29 | VIRUS RDRP NS5B POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2rg5:A (SER61) to (GLU160) PHENYLALANINE PYRROLOTRIAZINE P38 ALPHA MAP KINASE INHIBITOR COMPOUND 11B | SERINE/THREONINE-PROTEIN KINASE, KINASE, TRANSFERASE, P38 MAP KINASE
1qhm:A (GLY1528) to (VAL1603) ESCHERICHIA COLI PYRUVATE FORMATE LYASE LARGE DOMAIN | PYRUVATE FORMATE LYASE, ANAEROBIC, X-RAY CRYSTALLOGRAPHY, HOMODIMER, ENZYME MECHANISM, LYASE/TRANSFERASE COMPLEX
1qhm:B (GLY2528) to (VAL2603) ESCHERICHIA COLI PYRUVATE FORMATE LYASE LARGE DOMAIN | PYRUVATE FORMATE LYASE, ANAEROBIC, X-RAY CRYSTALLOGRAPHY, HOMODIMER, ENZYME MECHANISM, LYASE/TRANSFERASE COMPLEX
1qj5:A (GLN346) to (GLY394) CRYSTAL STRUCTURE OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE | AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, BIOTIN BIOSYNTHESIS
4yfu:D (ASN780) to (SER870) CRYSTAL STRUCTURE OF OPEN BACILLUS FRAGMENT DNA POLYMERASE BOUND TO DNA AND DTTP | PROTEIN-DNA COMPLEX, TRANSFERASE-DNA COMPLEX
1qlu:A (SER17) to (SER101) STRUCTURE OF THE H422A MUTANT VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH ISOEUGENOL | OXIDOREDUCTASE, FLAVOPROTEIN, METHANOL UTILIZATION, PEROXISOME, FLAVOENZYME, OXIDASE, CATALYSIS
1qlu:B (SER17) to (SER101) STRUCTURE OF THE H422A MUTANT VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH ISOEUGENOL | OXIDOREDUCTASE, FLAVOPROTEIN, METHANOL UTILIZATION, PEROXISOME, FLAVOENZYME, OXIDASE, CATALYSIS
3h2l:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH A NOVEL BICYCLIC DIHYDRO-PYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, HEPATITIS C, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING
3h2l:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH A NOVEL BICYCLIC DIHYDRO-PYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, HEPATITIS C, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING
3h2u:D (ASN72) to (LEU127) HUMAN RAVER1 RRM1, RRM2, AND RRM3 DOMAINS IN COMPLEX WITH HUMAN VINCULIN TAIL DOMAIN VT | FOCAL ADHESION, ACTIN CYTOSKELETON, RNP MOTIF, RNA BINDING, ALTERNATIVE SPLICING, CYTOPLASM, NUCLEUS, PHOSPHOPROTEIN, RNA-BINDING, CELL ADHESION
4jmp:A (LEU1097) to (ASP1157) CRYSTAL STRUCTURE OF THE CHIMERICAL PROTEIN CAPA2B2 | ROSSMANN FOLD, TYROSINE KINASE, TRANSFERASE
3h2v:F (ASN72) to (LEU127) HUMAN RAVER1 RRM1 DOMAIN IN COMPLEX WITH HUMAN VINCULIN TAIL DOMAIN VT | FOCAL ADHESION, ACTIN CYTOSKELETON, RNP MOTIF, RNA BINDING, ALTERNATIVE SPLICING, CYTOPLASM, NUCLEUS, PHOSPHOPROTEIN, RNA-BINDING, CELL ADHESION
3h2v:G (ASN72) to (LEU127) HUMAN RAVER1 RRM1 DOMAIN IN COMPLEX WITH HUMAN VINCULIN TAIL DOMAIN VT | FOCAL ADHESION, ACTIN CYTOSKELETON, RNP MOTIF, RNA BINDING, ALTERNATIVE SPLICING, CYTOPLASM, NUCLEUS, PHOSPHOPROTEIN, RNA-BINDING, CELL ADHESION
3h2v:H (GLN73) to (LEU127) HUMAN RAVER1 RRM1 DOMAIN IN COMPLEX WITH HUMAN VINCULIN TAIL DOMAIN VT | FOCAL ADHESION, ACTIN CYTOSKELETON, RNP MOTIF, RNA BINDING, ALTERNATIVE SPLICING, CYTOPLASM, NUCLEUS, PHOSPHOPROTEIN, RNA-BINDING, CELL ADHESION
3tvi:A (GLY312) to (ASN372) CRYSTAL STRUCTURE OF CLOSTRIDIUM ACETOBUTYLICUM ASPARTATE KINASE (CAAK): AN IMPORTANT ALLOSTERIC ENZYME FOR INDUSTRIAL AMINO ACIDS PRODUCTION | STRUCTURAL GENOMICS, ACT DOMAINS, REGULATORY DOMAINS, KINASE, TRANSFERASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
3tvi:C (GLY312) to (ASN372) CRYSTAL STRUCTURE OF CLOSTRIDIUM ACETOBUTYLICUM ASPARTATE KINASE (CAAK): AN IMPORTANT ALLOSTERIC ENZYME FOR INDUSTRIAL AMINO ACIDS PRODUCTION | STRUCTURAL GENOMICS, ACT DOMAINS, REGULATORY DOMAINS, KINASE, TRANSFERASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
3tvi:I (GLY312) to (ASN372) CRYSTAL STRUCTURE OF CLOSTRIDIUM ACETOBUTYLICUM ASPARTATE KINASE (CAAK): AN IMPORTANT ALLOSTERIC ENZYME FOR INDUSTRIAL AMINO ACIDS PRODUCTION | STRUCTURAL GENOMICS, ACT DOMAINS, REGULATORY DOMAINS, KINASE, TRANSFERASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
3tx1:A (MET1) to (GLY61) X-RAY CRYSTAL STRUCTURE OF LISTERIA MONOCYTOGENES EGD-E UDP-N- ACETYLENOLPYRUVYLGLUCOSAMINE REDUCTASE (MURB) | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, OXIDOREDUCTASE
1f1b:D (GLY26) to (ASN88) CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE P268A MUTANT IN THE R-STATE IN THE PRESENCE OF N-PHOSPHONACETYL-L-ASPARTATE | ASPARTATE TRANSCARBAMOYLASE, ASPARTATE CARBAMOYLTRANSFERASE, CIS- PROLINE, CIS-AMINO ACID, TRANSFERASE
3h59:A (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B WITH THIAZINE INHIBITOR 2 | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3h59:B (THR286) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B WITH THIAZINE INHIBITOR 2 | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
1f1h:A (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS | GLUTAMINE SYNTHETASE, THALLIUM IONS, LIGASE
1f1h:B (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS | GLUTAMINE SYNTHETASE, THALLIUM IONS, LIGASE
1f1h:C (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS | GLUTAMINE SYNTHETASE, THALLIUM IONS, LIGASE
1f1h:D (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS | GLUTAMINE SYNTHETASE, THALLIUM IONS, LIGASE
1f1h:E (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS | GLUTAMINE SYNTHETASE, THALLIUM IONS, LIGASE
1f1h:F (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS | GLUTAMINE SYNTHETASE, THALLIUM IONS, LIGASE
1f1h:G (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS | GLUTAMINE SYNTHETASE, THALLIUM IONS, LIGASE
1f1h:H (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS | GLUTAMINE SYNTHETASE, THALLIUM IONS, LIGASE
1f1h:I (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS | GLUTAMINE SYNTHETASE, THALLIUM IONS, LIGASE
1f1h:J (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS | GLUTAMINE SYNTHETASE, THALLIUM IONS, LIGASE
1f1h:K (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS | GLUTAMINE SYNTHETASE, THALLIUM IONS, LIGASE
1f1h:L (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS | GLUTAMINE SYNTHETASE, THALLIUM IONS, LIGASE
3tyv:A (THR286) to (TYR358) SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3tyv:B (THR286) to (TYR358) SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1quv:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF THE RNA DIRECTED RNA POLYMERASE OF HEPATITIS C VIRUS | RNA DEPENDENT RNA POLYMERASE, REPLICASE, HCV, NS5B, TRANSFERASE
3u1l:A (PRO153) to (TRP225) STRUCTURE OF THE MRNA SPLICING COMPLEX COMPONENT CWC2 | CSMP, ZINC FINGER, SPLICING
3u1m:A (PRO153) to (TRP225) STRUCTURE OF THE MRNA SPLICING COMPLEX COMPONENT CWC2 | CSMP, ZINC FINGER, MRNA SPLICING, SPLICING
3h98:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B 1B WITH (1,1-DIOXO-2H-[1,2, 4]BENZOTHIADIAZIN-3-YL) AZOLO[1,5-A]PYRIMIDINE DERIVATIVE | RNA POLYMERASE, NUCLEOTIDE BINDING, TRANSFERASE
3h98:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B 1B WITH (1,1-DIOXO-2H-[1,2, 4]BENZOTHIADIAZIN-3-YL) AZOLO[1,5-A]PYRIMIDINE DERIVATIVE | RNA POLYMERASE, NUCLEOTIDE BINDING, TRANSFERASE
1f52:A (GLN189) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP | GLUTAMINE SYNTHETASE, ADP, MPD, LIGASE
1f52:B (GLN189) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP | GLUTAMINE SYNTHETASE, ADP, MPD, LIGASE
1f52:C (GLN189) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP | GLUTAMINE SYNTHETASE, ADP, MPD, LIGASE
1f52:D (GLN189) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP | GLUTAMINE SYNTHETASE, ADP, MPD, LIGASE
1f52:E (GLN189) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP | GLUTAMINE SYNTHETASE, ADP, MPD, LIGASE
1f52:F (GLN189) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP | GLUTAMINE SYNTHETASE, ADP, MPD, LIGASE
1f52:G (GLN189) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP | GLUTAMINE SYNTHETASE, ADP, MPD, LIGASE
1f52:H (GLN189) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP | GLUTAMINE SYNTHETASE, ADP, MPD, LIGASE
1f52:I (GLN189) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP | GLUTAMINE SYNTHETASE, ADP, MPD, LIGASE
1f52:J (GLN189) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP | GLUTAMINE SYNTHETASE, ADP, MPD, LIGASE
1f52:K (GLN189) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP | GLUTAMINE SYNTHETASE, ADP, MPD, LIGASE
1f52:L (GLN189) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP | GLUTAMINE SYNTHETASE, ADP, MPD, LIGASE
4jtw:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COUPOUND 1 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jtw:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COUPOUND 1 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jtz:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 4 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jtz:B (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 4 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jty:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH COMPOUND 2 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jty:B (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH COMPOUND 2 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju1:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 6 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju1:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 6 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju3:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 8 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju3:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 8 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju4:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 22 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju4:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 22 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju6:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 24 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju6:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 24 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju7:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 24 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju7:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 24 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3u4r:A (VAL284) to (TYR358) NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE C2 ACYL SULFONAMIDES | NUCLEOTIDYL TRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3u4r:B (THR287) to (TYR358) NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE C2 ACYL SULFONAMIDES | NUCLEOTIDYL TRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4juo:C (ASN191) to (ASN253) A LOW-RESOLUTION THREE-GATE STRUCTURE OF TOPOISOMERASE IV FROM STREPTOCOCCUS PNEUMONIAE IN SPACE GROUP H32 | FULL-LENGTH PARE, PARC55, OPEN N-GATE, TOPOISOMERASE IIA, ATP BINDING, ISOMERASE-DNA COMPLEX
4jv0:A (LYS78) to (SER145) RING-OPENING OF THE -OH-PDG ADDUCT IN TERNARY COMPLEXES WITH THE SULFOLOBUS SOLFATARICUS DNA POLYMERASE DPO4 | TERNARY COMPLEX OF DPO4-DNA-DATP, DNA POLYMERASE, DNA ADDUCT, TRANSFERASE-DNA COMPLEX
4jv1:A (LYS78) to (SER145) TERNARY COMPLEX OF GAMMA-OHPDG ADDUCT MODIFIED DNA WITH DNA (-1 PRIMER) POLYMERASE IV AND INCOMING DGTP | TERNARY COMPLEX OF DPO4-DNA-DGTP, DNA POLYMERASE, DNA ADDUCT, TRANSFERASE-DNA COMPLEX
4jv2:A (GLU79) to (SER145) TERNARY COMPLEX OF GAMMA-OHPDG ADDUCT MODIFIED DNA WITH DNA (-1 PRIMER) POLYMERASE IV AND INCOMING DATP | TERNARY COMPLEX OF DPO4-DNA-DATP, DNA POLYMERASE, DNA ADDUCT, TRANSFERASE-DNA COMPLEX
4jvq:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 9 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4jvq:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 9 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1r0b:J (LYS34) to (ASN88) ASPARTATE TRANSCARBAMYLASE (ATCASE) OF ESCHERICHIA COLI: A NEW CRYSTALLINE R STATE BOUND TO PALA, OR TO PRODUCT ANALOGUES PHOSPHATE AND CITRATE | ASPARTATE TRANSCARBAMYLASE, ASPARTATE CARBAMOYLTRANSFERASE, PRODUCT ANALOGUE, CITRATE, PHOSPHATE, ATCASE-CITRATE- PHOSPHATE COMPLEX, R STATE
2uvu:A (GLU79) to (SER145) CRYSTAL STRUCTURES OF MUTANT DPO4 DNA POLYMERASES WITH 8- OXOG CONTAINING DNA TEMPLATE-PRIMER CONSTRUCTS | TRANSFERASE, DNA-DIRECTED DNA POLYMERASE, P2 DNA POLYMERASE IV, NUCLEOTIDYLTRANSFERASE, 7, MAGNESIUM, DNA DAMAGE, DNA REPAIR, DNA-BINDING, TRANSLESION DNA POLYMERASE, DNA- BINDING, METAL-BINDING, 8-DIHYDRO-8- OXODEOXYGUANOSINE, METAL- BINDING, MUTATOR PROTEIN, DNA REPLICATION
4jy1:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 5 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jy1:B (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 5 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jz7:D (GLN140) to (CYS192) CARBAMATE KINASE FROM GIARDIA LAMBLIA BOUND TO AMP-PNP | MODIFIED ROSSMANN FOLD, ATP CARBAMATE PHOSPHOTRANSFERASE, ADP, MG2+, CARBAMOYL PHOSPHATE, TRANSFERASE
4jz8:A (THR138) to (THR193) CARBAMATE KINASE FROM GIARDIA LAMBLIA BOUND TO CITRIC ACID | MODIFIED ROSSMANN FOLD, ATP CARBAMATE PHOSPHOTRANSFERASE, ADP, MG2+, CARBAMOYL PHOSPHATE, TRANSFERASE
4jz8:B (THR138) to (THR193) CARBAMATE KINASE FROM GIARDIA LAMBLIA BOUND TO CITRIC ACID | MODIFIED ROSSMANN FOLD, ATP CARBAMATE PHOSPHOTRANSFERASE, ADP, MG2+, CARBAMOYL PHOSPHATE, TRANSFERASE
4jz8:C (THR138) to (THR193) CARBAMATE KINASE FROM GIARDIA LAMBLIA BOUND TO CITRIC ACID | MODIFIED ROSSMANN FOLD, ATP CARBAMATE PHOSPHOTRANSFERASE, ADP, MG2+, CARBAMOYL PHOSPHATE, TRANSFERASE
4jz8:D (THR138) to (THR193) CARBAMATE KINASE FROM GIARDIA LAMBLIA BOUND TO CITRIC ACID | MODIFIED ROSSMANN FOLD, ATP CARBAMATE PHOSPHOTRANSFERASE, ADP, MG2+, CARBAMOYL PHOSPHATE, TRANSFERASE
4jz9:D (THR138) to (THR193) CARBAMATE KINASE FROM GIARDIA LAMBLIA BOUND TO CITRIC ACID | MODIFIED ROSSMANN FOLD, ATP CARBAMATE PHOSPHOTRANSFERASE, ADP, MG2+, CARBAMOYL PHOSPHATE, TRANSFERASE
1fe4:A (GLY14) to (GLY66) CRYSTAL STRUCTURE OF MERCURY-HAH1 | BETA-ALPHA-BETA-BETA-ALPHA-BETA, METAL TRANSPORT
1r3c:A (SER61) to (GLU160) THE STRUCTURE OF P38ALPHA C162S MUTANT | SERINE/THREONINE KINASE, MUTAGENESIS, STABILIZATION, TRANSFERASE
1fee:A (GLY13) to (GLY66) CRYSTAL STRUCTURE OF COPPER-HAH1 | BETA-ALPHA-BETA-BETA-ALPHA-BETA, TRANSPORT PROTEIN
2ej9:A (SER11) to (LEU90) CRYSTAL STRUCTURE OF BIOTIN PROTEIN LIGASE FROM METHANOCOCCUS JANNASCHII | BIOTIN BIOSYNTHESIS, MONOMER, X-RAY DIFFRACTION, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LIGASE
4k0e:A (ARG71) to (LEU127) X-RAY CRYSTAL STRUCTURE OF A HEAVY METAL EFFLUX PUMP, CRYSTAL FORM II | STRUCTURAL GENOMICS, PSI-BIOLOGY, CENTER FOR STRUCTURES OF MEMBRANE PROTEINS, CSMP, RESISTANCE-NODULATION-CELL DIVISION (RND) SUPERFAMILY, HEAVY METAL EFFLUX PUMP, ZNEB, ZNEC, INNER MEMBRANE, TRANSPORT PROTEIN
4k0j:B (THR66) to (LEU130) X-RAY CRYSTAL STRUCTURE OF A HEAVY METAL EFFLUX PUMP, CRYSTAL FORM I | STRUCTURAL GENOMICS, PSI-BIOLOGY, CENTER FOR STRUCTURES OF MEMBRANE PROTEINS, CSMP, RESISTANCE-NODULATION-CELL DIVISION (RND) SUPERFAMILY, HEAVY METAL EFFLUX PUMP, ZNEB, ZNEC, INNER MEMBRANE, TRANSPORT PROTEIN
4k0j:C (GLU62) to (LEU127) X-RAY CRYSTAL STRUCTURE OF A HEAVY METAL EFFLUX PUMP, CRYSTAL FORM I | STRUCTURAL GENOMICS, PSI-BIOLOGY, CENTER FOR STRUCTURES OF MEMBRANE PROTEINS, CSMP, RESISTANCE-NODULATION-CELL DIVISION (RND) SUPERFAMILY, HEAVY METAL EFFLUX PUMP, ZNEB, ZNEC, INNER MEMBRANE, TRANSPORT PROTEIN
4k0j:E (THR66) to (LEU130) X-RAY CRYSTAL STRUCTURE OF A HEAVY METAL EFFLUX PUMP, CRYSTAL FORM I | STRUCTURAL GENOMICS, PSI-BIOLOGY, CENTER FOR STRUCTURES OF MEMBRANE PROTEINS, CSMP, RESISTANCE-NODULATION-CELL DIVISION (RND) SUPERFAMILY, HEAVY METAL EFFLUX PUMP, ZNEB, ZNEC, INNER MEMBRANE, TRANSPORT PROTEIN
4k0j:F (GLU62) to (LEU127) X-RAY CRYSTAL STRUCTURE OF A HEAVY METAL EFFLUX PUMP, CRYSTAL FORM I | STRUCTURAL GENOMICS, PSI-BIOLOGY, CENTER FOR STRUCTURES OF MEMBRANE PROTEINS, CSMP, RESISTANCE-NODULATION-CELL DIVISION (RND) SUPERFAMILY, HEAVY METAL EFFLUX PUMP, ZNEB, ZNEC, INNER MEMBRANE, TRANSPORT PROTEIN
3hhk:A (THR287) to (TYR358) HCV NS5B POLYMERASE COMPLEX WITH A SUBSTITUTED BENZOTHIADIZINE | NS5B, POLYMERASE, HCV, INHHIBITOR, ATP-BINDING, ENVELOPE PROTEIN, HELICASE, HYDROLASE, MEMBRANE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3hhk:B (THR286) to (TYR358) HCV NS5B POLYMERASE COMPLEX WITH A SUBSTITUTED BENZOTHIADIZINE | NS5B, POLYMERASE, HCV, INHHIBITOR, ATP-BINDING, ENVELOPE PROTEIN, HELICASE, HYDROLASE, MEMBRANE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2v2q:A (PRO217) to (LEU266) ISPE IN COMPLEX WITH LIGAND | TRANSFERASE, 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL, AQUIFEX AEOLICUS, NUCLEOTIDE-BINDING, ISOPRENE BIOSYNTHESIS, KINASE, ATP-BINDING, NON-MEVALONATE
2v2v:B (PRO217) to (GLU267) ISPE IN COMPLEX WITH LIGAND | TRANSFERASE, 4-DIPHOSPHOCYTIDYL-2C-METHYL-D- ERYTHRITOL, AQUIFEX AEOLICUS, NUCLEOTIDE-BINDING, ISOPRENE BIOSYNTHESIS, KINASE, ATP-BINDING, NON-MEVALONATE
2v2z:A (GLU218) to (LEU266) ISPE IN COMPLEX WITH ADP AND CDPME | TRANSFERASE, 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL, AQUIFEX AEOLICUS, NUCLEOTIDE-BINDING, ISOPRENE BIOSYNTHESIS, KINASE, ATP-BINDING, NON-MEVALONATE
4k2r:A (ASP379) to (ASN471) STRUCTURAL BASIS FOR ACTIVATION OF ZAP-70 BY PHOSPHORYLATION OF THE SH2-KINASE LINKER | KINASE DOMAIN, SH2 DOMAIN, TRANSFERASE, ATP BINDING, CYTOPLAM
3udl:A (THR286) to (TYR358) 3-HETEROCYCLYL QUINOLONE BOUND TO HCV NS5B | HCV, POLYMERASE, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3udl:B (THR286) to (TYR358) 3-HETEROCYCLYL QUINOLONE BOUND TO HCV NS5B | HCV, POLYMERASE, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3udl:C (THR287) to (TYR358) 3-HETEROCYCLYL QUINOLONE BOUND TO HCV NS5B | HCV, POLYMERASE, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3udl:D (THR286) to (TYR358) 3-HETEROCYCLYL QUINOLONE BOUND TO HCV NS5B | HCV, POLYMERASE, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2v4q:A (GLU79) to (SER145) POST-INSERTION COMPLEX OF THE Y-FAMILY DNA POLYMERASE DPO4 WITH M1DG CONTAINING TEMPLATE DNA | DNA-DIRECTED DNA POLYMERASE, DNA-BINDING, METAL-BINDING, DNA REPLICATION, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, DNA ADDUCT, DNA DAMAGE, DNA REPAIR, TRANSFERASE, DPO4, M1DG, CYTOPLASM, MAGNESIUM, POLYMERASE
2v4r:A (GLU80) to (SER146) NON-PRODUCTIVE COMPLEX OF THE Y-FAMILY DNA POLYMERASE DPO4 WITH DGTP SKIPPING THE M1DG ADDUCT TO PAIR WITH THE NEXT TEMPLATE CYTOSINE | DNA-DIRECTED DNA POLYMERASE, DNA-BINDING, METAL-BINDING, DNA REPLICATION, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, DNA ADDUCT, DNA DAMAGE, DNA REPAIR, TRANSFERASE, DPO4, M1DG, CYTOPLASM, MAGNESIUM
3hkw:A (THR286) to (TYR358) HCV NS5B GENOTYPE 1A IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 6 | HCV POLYMERASE, SUBTYPE 1A, 1,5-BENZODIAZEPINE, TRANSFERASE
3hkw:B (THR287) to (TYR358) HCV NS5B GENOTYPE 1A IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 6 | HCV POLYMERASE, SUBTYPE 1A, 1,5-BENZODIAZEPINE, TRANSFERASE
3hkw:C (THR287) to (TYR358) HCV NS5B GENOTYPE 1A IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 6 | HCV POLYMERASE, SUBTYPE 1A, 1,5-BENZODIAZEPINE, TRANSFERASE
3hky:A (THR286) to (TYR358) HCV NS5B POLYMERASE GENOTYPE 1B IN COMPLEX WITH 1,5 BENZODIAZEPINE 6 | HEPATITIS C VIRUS, 1,5-BENZODIAZEPINE, GENOTYPE, NS5B, POLYMERASE, BIACORE, REPLICON, TRANSFERASE
3hky:B (VAL284) to (TYR358) HCV NS5B POLYMERASE GENOTYPE 1B IN COMPLEX WITH 1,5 BENZODIAZEPINE 6 | HEPATITIS C VIRUS, 1,5-BENZODIAZEPINE, GENOTYPE, NS5B, POLYMERASE, BIACORE, REPLICON, TRANSFERASE
1raa:D (ILE25) to (ASP87) CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | TRANSFERASE
1rae:D (ILE25) to (ASP87) CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | TRANSFERASE
1rba:A (TYR38) to (MET123) SUBSTITUTION OF ASP193 TO ASN AT THE ACTIVE SITE OF RIBULOSE-1,5- BISPHOSPHATE CARBOXYLASE RESULTS IN CONFORMATIONAL CHANGES | LYASE(CARBON-CARBON)
3hll:A (SER61) to (GLU160) CRYSTAL STRUCTURE OF HUMAN P38ALPHA COMPLEXED WITH PH-797804 | ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
1fpy:A (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH INHIBITOR PHOSPHINOTHRICIN | GLUTAMINE SYNTHETASE, PHOSPHINOTHRICIN, INHIBITION, LIGASE
1fpy:B (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH INHIBITOR PHOSPHINOTHRICIN | GLUTAMINE SYNTHETASE, PHOSPHINOTHRICIN, INHIBITION, LIGASE
1fpy:C (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH INHIBITOR PHOSPHINOTHRICIN | GLUTAMINE SYNTHETASE, PHOSPHINOTHRICIN, INHIBITION, LIGASE
1fpy:D (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH INHIBITOR PHOSPHINOTHRICIN | GLUTAMINE SYNTHETASE, PHOSPHINOTHRICIN, INHIBITION, LIGASE
1fpy:E (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH INHIBITOR PHOSPHINOTHRICIN | GLUTAMINE SYNTHETASE, PHOSPHINOTHRICIN, INHIBITION, LIGASE
1fpy:F (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH INHIBITOR PHOSPHINOTHRICIN | GLUTAMINE SYNTHETASE, PHOSPHINOTHRICIN, INHIBITION, LIGASE
1fpy:G (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH INHIBITOR PHOSPHINOTHRICIN | GLUTAMINE SYNTHETASE, PHOSPHINOTHRICIN, INHIBITION, LIGASE
1fpy:H (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH INHIBITOR PHOSPHINOTHRICIN | GLUTAMINE SYNTHETASE, PHOSPHINOTHRICIN, INHIBITION, LIGASE
1fpy:I (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH INHIBITOR PHOSPHINOTHRICIN | GLUTAMINE SYNTHETASE, PHOSPHINOTHRICIN, INHIBITION, LIGASE
1fpy:J (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH INHIBITOR PHOSPHINOTHRICIN | GLUTAMINE SYNTHETASE, PHOSPHINOTHRICIN, INHIBITION, LIGASE
1fpy:K (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH INHIBITOR PHOSPHINOTHRICIN | GLUTAMINE SYNTHETASE, PHOSPHINOTHRICIN, INHIBITION, LIGASE
1fpy:L (ALA188) to (PHE255) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH INHIBITOR PHOSPHINOTHRICIN | GLUTAMINE SYNTHETASE, PHOSPHINOTHRICIN, INHIBITION, LIGASE
1rdr:A (GLY292) to (ALA380) POLIOVIRUS 3D POLYMERASE | NUCLEOTIDYLTRANSFERASE, POLIOVIRUS, 3D, RNA-DEPENDENT, POLYMERASE
2v8p:B (PRO217) to (LEU266) ISPE IN COMPLEX WITH ADP AND CDP | 4-DIPHOSPHOCYTIDYL-2C-METHYL-D- ERYTHRITOL, AQUIFEX AEOLICUS, NUCLEOTIDE-BINDING, ISOPRENE BIOSYNTHESIS, KINASE, TRANSFERASE, ATP-BINDING, NON-MEVALONATE
2v9w:A (LYS78) to (SER145) COMPLEX STRUCTURE OF SULFOLOBUS SOLFATARICUS DPO4 AND DNA DUPLEX CONTAINING A HYDROPHOBIC THYMINE ISOSTERE 2,4- DIFLUOROTOLUENE NUCLEOTIDE IN THE TEMPLATE STRAND | DNA-DIRECTED DNA POLYMERASE, P2 DNA POLYMERASE IV, NUCLEOTIDYLTRANSFERASE, MUTATOR PROTEIN, DNA REPLICATION, 4-DIFLUOROTOLUENE, DNA REPAIR, DNA-BINDING, TRANSFERASE, METAL-BINDING, TRANSLESION DNA POLYMERASE, DDCTP, CYTOPLASM, MAGNESIUM, DNA DAMAGE
2v9w:B (ARG77) to (SER145) COMPLEX STRUCTURE OF SULFOLOBUS SOLFATARICUS DPO4 AND DNA DUPLEX CONTAINING A HYDROPHOBIC THYMINE ISOSTERE 2,4- DIFLUOROTOLUENE NUCLEOTIDE IN THE TEMPLATE STRAND | DNA-DIRECTED DNA POLYMERASE, P2 DNA POLYMERASE IV, NUCLEOTIDYLTRANSFERASE, MUTATOR PROTEIN, DNA REPLICATION, 4-DIFLUOROTOLUENE, DNA REPAIR, DNA-BINDING, TRANSFERASE, METAL-BINDING, TRANSLESION DNA POLYMERASE, DDCTP, CYTOPLASM, MAGNESIUM, DNA DAMAGE
4k8z:A (LYS507) to (LYS584) KOD POLYMERASE IN BINARY COMPLEX WITH DSDNA | DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
2va2:A (LYS78) to (SER145) COMPLEX STRUCTURE OF SULFOLOBUS SOLFATARICUS DPO4 AND DNA DUPLEX CONTAINING A HYDROPHOBIC THYMINE ISOSTERE 2,4- DIFLUOROTOLUENE NUCLEOTIDE IN THE TEMPLATE STRAND | TRANSFERASE-DNA COMPLEX, DNA-DIRECTED DNA POLYMERASE, P2 DNA POLYMERASE IV, TRANSFERASE, NUCLEOTIDYLTRANSFERASE, MUTATOR PROTEIN, DNA REPLICATION, DNA REPAIR, DNA-BINDING, METAL-BINDING, TRANSLESION DNA POLYMERASE, 2, DDCTP, MAGNESIUM, DNA DAMAGE
2va2:B (LYS78) to (SER145) COMPLEX STRUCTURE OF SULFOLOBUS SOLFATARICUS DPO4 AND DNA DUPLEX CONTAINING A HYDROPHOBIC THYMINE ISOSTERE 2,4- DIFLUOROTOLUENE NUCLEOTIDE IN THE TEMPLATE STRAND | TRANSFERASE-DNA COMPLEX, DNA-DIRECTED DNA POLYMERASE, P2 DNA POLYMERASE IV, TRANSFERASE, NUCLEOTIDYLTRANSFERASE, MUTATOR PROTEIN, DNA REPLICATION, DNA REPAIR, DNA-BINDING, METAL-BINDING, TRANSLESION DNA POLYMERASE, 2, DDCTP, MAGNESIUM, DNA DAMAGE
2va3:A (GLU79) to (SER145) COMPLEX STRUCTURE OF SULFOLOBUS SOLFATARICUS DPO4 AND DNA DUPLEX CONTAINING A HYDROPHOBIC THYMINE ISOSTERE 2,4- DIFLUOROTOLUENE NUCLEOTIDE IN THE TEMPLATE STRAND | DNA-DIRECTED DNA POLYMERASE, P2 DNA POLYMERASE IV, NUCLEOTIDYLTRANSFERASE, MUTATOR PROTEIN, DNA REPLICATION, 2, 4-DIFLUOROTOLUENE, DNA REPAIR, DNA-BINDING, TRANSFERASE, METAL-BINDING, TRANSLESION DNA POLYMERASE, DGTP, CYTOPLASM, MAGNESIUM, DNA DAMAGE
4kai:A (THR287) to (TYR358) HCV NS5B GT1B N316 WITH GSK5852A | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, RNA DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, REPLICATION- REPLICATION INHIBITOR COMPLEX
4kai:B (THR287) to (TYR358) HCV NS5B GT1B N316 WITH GSK5852A | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, RNA DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, REPLICATION- REPLICATION INHIBITOR COMPLEX
1fwk:A (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP | KINASE, TRANSFERASE
1fwk:B (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP | KINASE, TRANSFERASE
1fwk:C (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP | KINASE, TRANSFERASE
1fwk:D (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP | KINASE, TRANSFERASE
4kb7:A (THR287) to (TYR358) HCV NS5B GT1B N316Y WITH CMPD 32 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, RNA-DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX
4kb7:B (THR287) to (TYR358) HCV NS5B GT1B N316Y WITH CMPD 32 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, RNA-DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX
4kbi:A (THR287) to (TYR358) HCV NS5B GT1B N316Y WITH CMPD 4 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, POLYMERASE, RNA DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX
4kbi:B (THR287) to (TYR358) HCV NS5B GT1B N316Y WITH CMPD 4 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, POLYMERASE, RNA DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX
4ke5:A (THR287) to (TYR358) HCV NS5B GT1B N316Y WITH GSK5852 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, POLYMERASE, RNA REPLICATION, REPLICATION- REPLICATION INHIBITOR COMPLEX
4ke5:B (SER288) to (TYR358) HCV NS5B GT1B N316Y WITH GSK5852 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, POLYMERASE, RNA REPLICATION, REPLICATION- REPLICATION INHIBITOR COMPLEX
3ung:C (PRO639) to (ILE716) STRUCTURE OF THE CMR2 SUBUNIT OF THE CRISPR RNA SILENCING COMPLEX | FERREDOXIN FOLD, NUCLEOTIDE-BINDING, POLYMERASE, CMR COMPLEX, UNKNOWN FUNCTION
1g51:B (SER1278) to (GLU1356) ASPARTYL TRNA SYNTHETASE FROM THERMUS THERMOPHILUS AT 2.4 A RESOLUTION | AMINOACYL TRNA SYNTHETASE, LIGASE
4kgk:B (GLN47) to (GLN133) BACTERIAL TRNA(HIS) GUANYLYLTRANSFERASE (THG1)-LIKE PROTEIN IN COMPLEX WITH GTP | POLYMERASE-LIKE CATALYTIC DOMAIN, TRANSFERASE, ATP BINDING, GTP BINDING, TRNA BINDING
4kgv:B (ILE25) to (ASN88) THE R STATE STRUCTURE OF E. COLI ATCASE WITH ATP BOUND | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, COMPETING PATHWAY, PRODUCT ACTIVATION, ALLOSTERY, TRANSFERASE
3upf:A (ASP328) to (GLN383) CRYSTAL STRUCTURE OF MURINE NOROVIRUS RNA-DEPENDENT RNA POLYMERASE BOUND TO NF023 | MURINE NOROVIRUS, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3upf:B (ASP328) to (GLN383) CRYSTAL STRUCTURE OF MURINE NOROVIRUS RNA-DEPENDENT RNA POLYMERASE BOUND TO NF023 | MURINE NOROVIRUS, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3upf:C (ASP328) to (GLN383) CRYSTAL STRUCTURE OF MURINE NOROVIRUS RNA-DEPENDENT RNA POLYMERASE BOUND TO NF023 | MURINE NOROVIRUS, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4khm:A (THR286) to (TYR358) HCV NS5B GT1A WITH GSK5852 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DEPENDENT RNA POLYMERASE, RNA DIRECTED RNA POLYMERASE, REPLICATION- REPLICATION INHIBITOR COMPLEX
4khm:B (THR286) to (TYR358) HCV NS5B GT1A WITH GSK5852 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DEPENDENT RNA POLYMERASE, RNA DIRECTED RNA POLYMERASE, REPLICATION- REPLICATION INHIBITOR COMPLEX
3uph:A (THR287) to (TYR358) SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3uph:B (THR287) to (TYR358) SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3upi:A (SER288) to (TYR358) SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3upi:B (THR287) to (TYR358) SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2vf3:B (PRO217) to (LEU266) AQUIFEX AEOLICUS ISPE IN COMPLEX WITH LIGAND | ISPE, KINASE, AQUIFEX, TRANSFERASE, ATP-BINDING, ISOPRENE BIOSYNTHESIS, NON-MEVALONATE, NUCLEOTIDE-BINDING
3ups:A (ASP15) to (GLY84) CRYSTAL STRUCTURE OF IOJAP-LIKE PROTEIN FROM ZYMOMONAS MOBILIS | PSI-BIOLOGY, MCSG, MIDWEST CENTER FOR STRUCTURAL GENOMICS, UNKNOWN FUNCTION, STRUCTURAL GENOMICS
3uqs:A (ASP328) to (GLN383) CRYSTAL STRUCTURES OF MURINE NOROVIRUS RNA-DEPENDENT RNA POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE
3uqs:B (ASP328) to (GLN383) CRYSTAL STRUCTURES OF MURINE NOROVIRUS RNA-DEPENDENT RNA POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE
3uqs:C (ASP328) to (GLN383) CRYSTAL STRUCTURES OF MURINE NOROVIRUS RNA-DEPENDENT RNA POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE
3ur0:A (ASP328) to (GLN383) CRYSTAL STRUCTURES OF MURINE NOROVIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH SURAMIN | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ur0:B (PRO329) to (GLN383) CRYSTAL STRUCTURES OF MURINE NOROVIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH SURAMIN | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ur0:C (ASP328) to (GLN383) CRYSTAL STRUCTURES OF MURINE NOROVIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH SURAMIN | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3hoy:A (THR1208) to (ASP1288) COMPLETE RNA POLYMERASE II ELONGATION COMPLEX VI | RNA POLYMERASE II, METAL-BINDING, TRANSCRIPTION BUBBLE, ELONGATION COMPLEX, TRANSCRIPTION, DNA-RNA MISMATCH, RNA FRAYING, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, MRNA PROCESSING, TRANSCRIPTION,TRANSFERASE/DNA/RNA HYBRID COMPLEX
4kip:A (SER61) to (GLU160) CRYSTAL STRUCTURE OF MITOGEN-ACTIVATED PROTEIN KINASE 14 (P38-H5) COMPLEX WITH 2-(2-CHLOROPHENYL)-N-(5-(CYCLOPROPYLCARBAMOYL)-2- METHYLPHENYL)-1,3-THIAZOLE-5-CARBOXAMIDE | SERINE/THREONINE-PROTEIN KINASE, KINASE, TRANSFERASE, P38 MAP KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4z7c:A (ASN260) to (SER313) DIPHOSPHOMEVALONATE DECARBOXYLASE FROM THE SULFOLOBUS SOLFATARICUS, SPACE GROUP H32 | DIPHOSPHOMEVALONATE DECARBOXYLASE, SULFOLOBUS SOLFATARICUS, DISULFIDE BOND, THERMOSTABILITY, LYASE
4z7g:A (GLU664) to (PHE775) CRYSTAL STRUCTURE OF HUMAN IRE1 CYTOPLASMIC KINASE-RNASE REGION - APO | TRANSFERASE, KINASE, RNASE, UNFOLDED PROTEIN RESPONSE
4z7g:B (GLU664) to (PHE775) CRYSTAL STRUCTURE OF HUMAN IRE1 CYTOPLASMIC KINASE-RNASE REGION - APO | TRANSFERASE, KINASE, RNASE, UNFOLDED PROTEIN RESPONSE
3uvq:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH A DIBENZOSUBERONE DERIVATIVE | SELECTIVE P38 INHIBITOR, SAR, DIBENZOSUBERONE DERIVATIVE, PROTEIN KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1s4e:A (GLU284) to (VAL343) PYROCOCCUS FURIOSUS GALACTOKINASE IN COMPLEX WITH GALACTOSE, ADP AND MAGNESIUM | GHMP KINASE SUPERFAMILY, P-LOOP, TRANSFERASE
1s4e:B (CYS282) to (VAL343) PYROCOCCUS FURIOSUS GALACTOKINASE IN COMPLEX WITH GALACTOSE, ADP AND MAGNESIUM | GHMP KINASE SUPERFAMILY, P-LOOP, TRANSFERASE
1s4e:C (GLU284) to (VAL343) PYROCOCCUS FURIOSUS GALACTOKINASE IN COMPLEX WITH GALACTOSE, ADP AND MAGNESIUM | GHMP KINASE SUPERFAMILY, P-LOOP, TRANSFERASE
1s4e:E (CYS282) to (VAL343) PYROCOCCUS FURIOSUS GALACTOKINASE IN COMPLEX WITH GALACTOSE, ADP AND MAGNESIUM | GHMP KINASE SUPERFAMILY, P-LOOP, TRANSFERASE
1s4e:F (CYS282) to (VAL343) PYROCOCCUS FURIOSUS GALACTOKINASE IN COMPLEX WITH GALACTOSE, ADP AND MAGNESIUM | GHMP KINASE SUPERFAMILY, P-LOOP, TRANSFERASE
1s4e:H (CYS282) to (VAL343) PYROCOCCUS FURIOSUS GALACTOKINASE IN COMPLEX WITH GALACTOSE, ADP AND MAGNESIUM | GHMP KINASE SUPERFAMILY, P-LOOP, TRANSFERASE
1s4e:I (CYS282) to (VAL343) PYROCOCCUS FURIOSUS GALACTOKINASE IN COMPLEX WITH GALACTOSE, ADP AND MAGNESIUM | GHMP KINASE SUPERFAMILY, P-LOOP, TRANSFERASE
1s4f:C (THR410) to (ARG490) CRYSTAL STRUCTURE OF RNA-DEPENDENT RNA POLYMERASE CONSTRUCT 2 FROM BOVINE VIRAL DIARRHEA VIRUS (BVDV) | POLYMERASE, RNA SYNTHESIS, PRIMER INDEPENDENT INITIATION, DE NOVO INITIATION, BOVINE VIRAL DIARRHEA VIRUS, BVDV, REPLICATION, RNA BINDING PROTEIN
4zaj:A (ASN3) to (ILE84) 2.2 ANGSTROM CRYSTAL STRUCTURE OF A HUMAN ARGINYL-TRNA SYNTHETASE | TRNA ARGININE SYNTHETASE ARG-TRNA, LIGASE
3ht4:H (ALA286) to (ALA355) CRYSTAL STRUCTURE OF THE Q81A77_BACCR PROTEIN FROM BACILLUS CEREUS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET BCR213 | LYASE, PUTATIVE CYSTATHIONINE BEAT-LYASE, ALUMINIUM RESISTANCE PROTEIN, Q81A77_BACCR, NESG, BCR213, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM
3hub:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH SCIOS-469 | DFG-IN, GLYCINE-RICH LOOP, SCIOS-469, ALTERNATIVE SPLICING, ATP- BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
4zck:A (GLN412) to (THR468) CRYSTAL STRUCTURE OF C-TERMINAL FRAGMENT OF ESCHERICHIA COLI BIPA/TYPA | BIPA, GTPASE, NUCLEOTIDE, GTP-BINDING PROTEIN
3hul:A (LEU225) to (LEU276) STRUCTURE OF PUTATIVE HOMOSERINE KINASE THRB FROM LISTERIA MONOCYTOGENES | STRUCTURAL GENOMICS, PUTATIVE HOMOSERINE KINASE, THRB, AMINO-ACID BIOSYNTHESIS, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, THREONINE BIOSYNTHESIS, TRANSFERASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
3hul:B (HIS224) to (LEU276) STRUCTURE OF PUTATIVE HOMOSERINE KINASE THRB FROM LISTERIA MONOCYTOGENES | STRUCTURAL GENOMICS, PUTATIVE HOMOSERINE KINASE, THRB, AMINO-ACID BIOSYNTHESIS, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, THREONINE BIOSYNTHESIS, TRANSFERASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
4zcm:B (GLN412) to (HIS471) CRYSTAL STRUCTURE OF ESCHERICHIA COLI GTPASE BIPA/TYPA COMPLEXED WITH PPGPP | BIPA, GTPASE, NUCLEOTIDE, GTP-BINDING PROTEIN
3hv4:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH RL51 | DFG-OUT, TYPE II, RL51, QUINOLINE-PYRAZOLOUREA, HYBRID, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
2fsl:X (SER61) to (GLU160) MITOGEN ACTIVATED PROTEIN KINASE P38ALPHA (D176A+F327S) ACTIVATING MUTANT FORM-A | MITOGEN ACTIVATED PROTEIN KINASE, P38, ACTIVE MUTANTS, LIPIDS, MAP KINASE INSERTION, AUTOPHOSPHORYLATION, TRANSFERASE
2fso:X (SER61) to (GLU160) MITOGEN ACTIVATED PROTEIN KINASE P38ALPHA (D176A) ACTIVATING MUTANT | MITOGEN ACTIVATED PROTEIN KINASE, P38, ACTIVE MUTANTS, LIPIDS, MAP KINASE INSERTION, AUTOPHOSPHORYLATION, TRANSFERASE
3hx9:A (ARG26) to (GLU93) STRUCTURE OF HEME-DEGRADER, MHUD (RV3592), FROM MYCOBACTERIUM TUBERCULOSIS WITH TWO HEMES BOUND IN ITS ACTIVE SITE | DI-HEME, BETA BARREL, DIMER, OXIDOREDUCTASE
3hx9:B (ARG26) to (GLU93) STRUCTURE OF HEME-DEGRADER, MHUD (RV3592), FROM MYCOBACTERIUM TUBERCULOSIS WITH TWO HEMES BOUND IN ITS ACTIVE SITE | DI-HEME, BETA BARREL, DIMER, OXIDOREDUCTASE
3hxw:A (SER3) to (TYR132) CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS IN COMPLEX WITH SERSA | AMINOACYL-TRNA SYNTHETASE, LIGASE, PROTEIN BIOSYNTHESIS, NUCLEOTIDE- BINDING, AMINO ACID-BINDING, ATP-BINDING, METAL-BINDING, ZINC-FINGER
2fvc:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF NS5B BK STRAIN (DELTA 24) IN COMPLEX WITH A 3-(1, 1-DIOXO-2H-(1,2,4)-BENZOTHIADIAZIN-3-YL)-4-HYDROXY-2(1H)-QUINOLINONE | HCV POLYMERASE, THIADIAZIN INHIBITOR, TRANSFERASE
2fvc:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF NS5B BK STRAIN (DELTA 24) IN COMPLEX WITH A 3-(1, 1-DIOXO-2H-(1,2,4)-BENZOTHIADIAZIN-3-YL)-4-HYDROXY-2(1H)-QUINOLINONE | HCV POLYMERASE, THIADIAZIN INHIBITOR, TRANSFERASE
3v4i:B (GLN161) to (HIS235) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) WITH DNA AND AZTTP | HIV-1 REVERSE TRANSCRIPTASE, ZIDOVUDINE, RT-DNA COMPLEX, TRANSFERASE- DNA COMPLEX, DRUG RESISTANCE MUTATION, AIDS, DNA RECOMBINATION, DNA- DIRECTED DNA POLYMERASE, RNASE H, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDYLTRANSFERASE, RNA-DIRECTED DNA POLYMERASE TRANSFERASE, TRANSFERASE-DNA COMPLEX COMPLEX
1set:B (GLU196) to (PRO240) CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE | LIGASE, SYNTHETASE
1gnk:B (LEU13) to (GLU95) GLNK, A SIGNAL PROTEIN FROM E. COLI | SIGNALING PROTEIN
3v6k:A (LYS78) to (SER145) REPLICATION OF N2,3-ETHENOGUANINE BY DNA POLYMERASES | SULFOLOBUS SOLFATARICUS DNA POLYMERASE IV, DPO4, ETHENOGUANINE, DNA ADDUCT, DNA LESION, DNA POLYMERASE, DNA REPLICATION, LESION BYPASS, 2'-FLUORO ARABINOSE, N2,3-ETHENOGUANINE, TRANSFERASE-DNA COMPLEX
3v6k:J (ARG77) to (SER145) REPLICATION OF N2,3-ETHENOGUANINE BY DNA POLYMERASES | SULFOLOBUS SOLFATARICUS DNA POLYMERASE IV, DPO4, ETHENOGUANINE, DNA ADDUCT, DNA LESION, DNA POLYMERASE, DNA REPLICATION, LESION BYPASS, 2'-FLUORO ARABINOSE, N2,3-ETHENOGUANINE, TRANSFERASE-DNA COMPLEX
2fyw:A (GLY108) to (VAL164) CRYSTAL STRUCTURE OF A CONSERVED PROTEIN OF UNKNOWN FUNCTION FROM STREPTOCOCCUS PNEUMONIAE | STRUCTURAL GENOMICS, HYPOTHETICAL PROTEIN, PSI, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, PROTEIN STRUCTURE INITIATIVE, UNKNOWN FUNCTION
2fyw:C (ASN110) to (VAL164) CRYSTAL STRUCTURE OF A CONSERVED PROTEIN OF UNKNOWN FUNCTION FROM STREPTOCOCCUS PNEUMONIAE | STRUCTURAL GENOMICS, HYPOTHETICAL PROTEIN, PSI, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, PROTEIN STRUCTURE INITIATIVE, UNKNOWN FUNCTION
2fzc:B (ILE25) to (ASN88) THE STRUCTURE OF WILD-TYPE E. COLI ASPARTATE TRANSCARBAMOYLASE IN COMPLEX WITH NOVEL T STATE INHIBITORS AT 2.10 RESOLUTION | INHIBITORS, ALLOSTERIC TRANSITION, XRAY STRUCTURES, TRANSFERASE
2fzg:B (ILE25) to (ASN88) THE STRUCTURE OF WILD-TYPE E. COLI ASPARTATE TRANSCARBAMOYLASE IN COMPLEX WITH NOVEL T STATE INHIBITORS AT 2.25 RESOLUTION | INHIBITORS, ALLOSTERIC TRANSITION, XRAY STRUCTURES, TRANSFERASE
2fzg:D (ILE25) to (ASN88) THE STRUCTURE OF WILD-TYPE E. COLI ASPARTATE TRANSCARBAMOYLASE IN COMPLEX WITH NOVEL T STATE INHIBITORS AT 2.25 RESOLUTION | INHIBITORS, ALLOSTERIC TRANSITION, XRAY STRUCTURES, TRANSFERASE
1sh0:A (SER328) to (GLU383) CRYSTAL STRUCTURE OF NORWALK VIRUS POLYMERASE (TRICLINIC) | RNA POLYMERASE, VIRAL REPLICATION ENZYME, TRANSFERASE
1sh0:B (SER328) to (GLU383) CRYSTAL STRUCTURE OF NORWALK VIRUS POLYMERASE (TRICLINIC) | RNA POLYMERASE, VIRAL REPLICATION ENZYME, TRANSFERASE
1sh2:A (SER328) to (GLU383) CRYSTAL STRUCTURE OF NORWALK VIRUS POLYMERASE (METAL-FREE, CENTERED ORTHORHOMBIC) | RNA POLYMERASE, VIRAL ENZYME, VIRAL REPLICATION, TRANSFERASE
2voy:A (CYS14) to (LEU70) CRYOEM MODEL OF COPA, THE COPPER TRANSPORTING ATPASE FROM ARCHAEOGLOBUS FULGIDUS | HYDROLASEP-TYPE ATPASE, CRYO-EM, HELICAL RECONSTRUCTION, MEMBRANE PROTEIN, COPPER TRANSPORTER, METAL BINDING DOMAIN, HYDROLASE
3i24:A (THR51) to (GLU143) CRYSTAL STRUCTURE OF A HIT FAMILY HYDROLASE PROTEIN FROM VIBRIO FISCHERI. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ID VFR176 | HIT FAMILY HYDROLASE, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, HYDROLASE
3i24:B (THR51) to (ARG141) CRYSTAL STRUCTURE OF A HIT FAMILY HYDROLASE PROTEIN FROM VIBRIO FISCHERI. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ID VFR176 | HIT FAMILY HYDROLASE, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, HYDROLASE
1gpm:A (LYS418) to (TYR512) ESCHERICHIA COLI GMP SYNTHETASE COMPLEXED WITH AMP AND PYROPHOSPHATE | CLASS I GLUTAMINE AMIDOTRANSFERASE, N-TYPE ATP PYROPHOSPHATASE, TRANSFERASE (GLUTAMINE AMIDOTRANSFERASE)
4zit:C (THR600) to (PHE666) CRYSTAL STRUCTURE OF ACRB IN P21 SPACE GROUP | ACRB, RND EFFLUX PUMP, BACTERIAL MULTIDRUG RESISTANCE, EXPORT MECHANISM, TRANSPORT PROTEIN
4zit:D (THR600) to (PHE666) CRYSTAL STRUCTURE OF ACRB IN P21 SPACE GROUP | ACRB, RND EFFLUX PUMP, BACTERIAL MULTIDRUG RESISTANCE, EXPORT MECHANISM, TRANSPORT PROTEIN
3i6p:A (LEU12) to (PRO76) ETHANOLAMINE UTILIZATION MICROCOMPARTMENT SHELL SUBUNIT, EUTM | STRUCTURAL PROTEIN
3i6p:B (LEU12) to (PRO76) ETHANOLAMINE UTILIZATION MICROCOMPARTMENT SHELL SUBUNIT, EUTM | STRUCTURAL PROTEIN
1suq:B (MET164) to (ASP237) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R185545 | AIDS, HIV, DRUG DESIGN, REVERSE TRANSCRIPTASE, RT, PROTEIN- INHIBITOR COMPLEX, DRUG RESISTANCE, TRANSFERASE
1gx5:A (THR287) to (TYR358) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH GTP AND MANGANESE | TRANSFERASE, POLYPROTEIN, GLYCOPROTEIN, RNA-DIRECTED RNA POLYMERASE, CORE PROTEIN, COAT PROTEIN, ENVELOPE PROTEIN, HELICASE, ATP BINDING, TRANSMEMBRANE, NONSTRUCTURAL PROTEIN
1gx6:A (THR286) to (TYR358) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH UTP AND MANGANESE | POLYMERASE, RNA-DEPENDENT RNA POLYMERASE, VIRUS REPLICATION, INITIATION, POLYPROTEIN, GLYCOPROTEIN, TRANSFERASE, RNA-DIRECTED RNA POLYMERASE
2gc8:A (THR286) to (TYR358) STRUCTURE OF A PROLINE SULFONAMIDE INHIBITOR BOUND TO HCV NS5B POLYMERASE | TRANSFERASE
2gc8:B (THR286) to (TYR358) STRUCTURE OF A PROLINE SULFONAMIDE INHIBITOR BOUND TO HCV NS5B POLYMERASE | TRANSFERASE
1sz7:A (PHE71) to (PHE150) CRYSTAL STRUCTURE OF HUMAN BET3 | ALPHA-BETA PLAIT, TRAPP COMPLEX, PALMITOYLATED, TRANSPORT PROTEIN
2ghl:A (SER61) to (GLU160) MUTANT MUS MUSCULUS P38 KINASE DOMAIN IN COMPLEX WITH INHIBITOR PG-874743 | MAP KINASE P38, P38, TRANSFERASE
2ghp:A (ASP223) to (LEU286) CRYSTAL STRUCTURE OF THE N-TERMINAL 3 RNA BINDING DOMAINS OF THE YEAST SPLICING FACTOR PRP24 | RNA CHAPERONE, RNA BINDING DOMAIN, RNA RECOGNITION MOTIF, SPLICING FACTOR, SNRNP, SPLICEOSOME, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS, CESG, RNA BINDING PROTEIN
2giq:A (THR286) to (TYR358) HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B WITH NNI-2 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE
2giq:B (THR286) to (TYR358) HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B WITH NNI-2 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE
2gir:A (THR286) to (TYR358) HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B WITH NNI-1 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE
2gir:B (THR287) to (TYR358) HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B WITH NNI-1 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE
2gj3:B (ILE26) to (LYS105) CRYSTAL STRUCTURE OF THE FAD-CONTAINING PAS DOMAIN OF THE PROTEIN NIFL FROM AZOTOBACTER VINELANDII. | PAS DOMAIN, FAD, REDOX SENSOR, ATOMIC RESOLUTION, TRANSFERASE
2gls:A (GLN189) to (PHE255) REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION | LIGASE(AMIDE SYNTHETASE)
2gls:B (GLN189) to (PHE255) REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION | LIGASE(AMIDE SYNTHETASE)
2gls:C (GLN189) to (PHE255) REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION | LIGASE(AMIDE SYNTHETASE)
2gls:D (GLN189) to (PHE255) REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION | LIGASE(AMIDE SYNTHETASE)
2gls:E (GLN189) to (PHE255) REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION | LIGASE(AMIDE SYNTHETASE)
2gls:F (GLN189) to (PHE255) REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION | LIGASE(AMIDE SYNTHETASE)
2gls:G (GLN189) to (PHE255) REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION | LIGASE(AMIDE SYNTHETASE)
2gls:H (GLN189) to (PHE255) REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION | LIGASE(AMIDE SYNTHETASE)
2gls:I (GLN189) to (PHE255) REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION | LIGASE(AMIDE SYNTHETASE)
2gls:J (GLN189) to (PHE255) REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION | LIGASE(AMIDE SYNTHETASE)
2gls:K (GLN189) to (PHE255) REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION | LIGASE(AMIDE SYNTHETASE)
2gls:L (GLN189) to (PHE255) REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION | LIGASE(AMIDE SYNTHETASE)
4zmu:B (HIS232) to (CYS294) DCSBIS, A DIGUANYLATE CYCLASE FROM PSEUDOMONAS AERUGINOSA | CELL MOTILITIES, DIGUANYL CYCLASE, GGDEF DOMAIN, GAF DOMAIN, LYASE
4zmm:A (HIS232) to (CYS294) GGDEF DOMAIN OF DCSBIS COMPLEXED WITH C-DI-GMP | CELL MOTILITIES, DIGUANYL CYCLASE, GGDEF DOMAIN, TRANSFERASE
4zo0:C (GLN50) to (THR135) X-RAY STRUCTURE OF AAV-2 ORIGIN BINDING DOMAIN | ADENO-ASSOCIATED VIRUS, HUH NUCLEASE, DNA BINDING PROTEIN, HYDROLASE
2w1r:A (ASP57) to (ASP116) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF B. SUBTILIS SPOVT | REGULATORY GAF DOMAIN OF SPOVT, TRANSCRIPTION, TRANSCRIPTION REGULATION, REPRESSOR, ACTIVATOR, SPORULATION, DNA-BINDING
1h72:C (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH HSE | TRANSFERASE, KINASE, THREONINE BIOSYNTHESIS
1h73:A (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH THREONINE | TRANSFERASE, KINASE, THREONINE BIOSYNTHESIS
1h74:A (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE | TRANSFERASE, KINASE
1h74:B (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE | TRANSFERASE, KINASE
1h74:C (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE | TRANSFERASE, KINASE
1h74:D (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE | TRANSFERASE, KINASE
3igv:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL MONOCYCLIC DIHYDRO-PYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, HYDROLASE, ANTIVIRAL, METAL BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, ATP-BINDING, DISULFIDE BOND, HOST-VIRUS INTERACTION, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3igv:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL MONOCYCLIC DIHYDRO-PYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, HYDROLASE, ANTIVIRAL, METAL BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, ATP-BINDING, DISULFIDE BOND, HOST-VIRUS INTERACTION, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
2w8k:A (GLU79) to (SER145) Y-FAMILY DNA POLYMERASE DPO4 BYPASSING N2-NAPHTHYL-GUANINE ADDUCT IN SYN ORIENTATION | DNA-DIRECTED DNA POLYMERASE, DNA, DPO4, ADDUCT, N2-ALKYL, CYTOPLASM, MAGNESIUM, TRANSFERASE, METAL-BINDING, MUTATOR PROTEIN, DNA REPLICATION, NUCLEOTIDYLTRANSFERASE, COMPLEX, POLYMERASE, DNA DAMAGE, DNA REPAIR, DNA-BINDING, TRANSFERASE/DNA
2w8l:A (GLU79) to (SER145) Y-FAMILY DNA POLYMERASE DPO4 BYPASSING N2-NAPHTHYL-GUANINE ADDUCT IN ANTI ORIENTATION | DNA-DIRECTED DNA POLYMERASE, DNA, DPO4, ADDUCT, N2-ALKYL, CYTOPLASM, MAGNESIUM, TRANSFERASE, METAL-BINDING, MUTATOR PROTEIN, DNA REPLICATION, NUCLEOTIDYLTRANSFERASE, COMPLEX, POLYMERASE, DNA DAMAGE, DNA REPAIR, DNA-BINDING, TRANSFERASE/DNA
2h3e:B (ILE25) to (ASN88) STRUCTURE OF WILD-TYPE E. COLI ASPARTATE TRANSCARBAMOYLASE IN THE PRESENCE OF N-PHOSPHONACETYL-L-ISOASPARAGINE AT 2.3A RESOLUTION | COOPERATIVITY, TRANSFERASE
2w9a:A (GLU79) to (SER145) TERNARY COMPLEX OF DPO4 BOUND TO N2,N2-DIMETHYL- DEOXYGUANOSINE MODIFIED DNA WITH INCOMING DGTP | TRANSFERASE DNA COMPLEX, N2-DIMETHYL-G, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, DNA-DIRECTED DNA POLYMERASE, DNA DAMAGE, DNA REPAIR, DNA-BINDING, TRANSFERASE, DNA REPLICATION, DNA, DPO4, ADDUCT, CYTOPLASM, MAGNESIUM, POLYMERASE
2w9b:B (LYS78) to (SER145) BINARY COMPLEX OF DPO4 BOUND TO N2,N2-DIMETHYL- DEOXYGUANOSINE MODIFIED DNA | DNA-DIRECTED DNA POLYMERASE, N2-DIMETHYL-G, METAL-BINDING, MUTATOR PROTEIN, DNA DAMAGE, DNA REPAIR, DNA-BINDING, TRANSFERASE, DNA REPLICATION, NUCLEOTIDYLTRANSFERASE, TRANSFERASE/DNA, DNA, DPO4, ADDUCT, CYTOPLASM, MAGNESIUM, POLYMERASE
2w9c:B (GLU79) to (SER145) TERNARY COMPLEX OF DPO4 BOUND TO N2,N2-DIMETHYL- DEOXYGUANOSINE MODIFIED DNA WITH INCOMING DTTP | DNA-DIRECTED DNA POLYMERASE, N2-DIMETHYL-G, METAL-BINDING, MUTATOR PROTEIN, DNA DAMAGE, DNA REPAIR, DNA-BINDING, TRANSFERASE, DNA REPLICATION, NUCLEOTIDYLTRANSFERASE, TRANSFERASE/DNA, DNA, DPO4, ADDUCT, CYTOPLASM, MAGNESIUM, POLYMERASE
1tp7:B (SER293) to (PRO355) CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE FROM HUMAN RHINOVIRUS 16 | RHINOVIRUS, RNA, POLYMERASE, 3D, TRANSFERASE
2hai:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE IN COMPLEX WITH NOVEL CLASS OF DIHYDROPYRONE-CONTAINING INHIBITOR. | HCV RNA POLYMERASE, TRANSFERASE
2wcx:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN COMPLEX WITH THIENOPYRROLE-BASED FINGER-LOOP INHIBITORS | ENVELOPE PROTEIN, HEPATITIS C VIRUS, RNA-DEPENDENT RNA-POLYMERASE, NUCLEOTIDE-BINDING, ALLOSTERIC INHIBITOR, NON NUCLEOSIDE INHIBITOR, NNI, HCV, NS5B, MEMBRANE, HELICASE, HYDROLASE, POLYMERASE, ATP-BINDING, RNA-BINDING, GENOTYPE 1B, VIRAL PROTEIN, TRANSMEMBRANE, RNA REPLICATION
3iw5:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH AN INDOLE DERIVATIVE | DFG-OUT, TYPE-I, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3iw8:A (SER61) to (GLU160) STRUCTURE OF INACTIVE HUMAN P38 MAP KINASE IN COMPLEX WITH A THIAZOLE-UREA | DFG-OUT, TYPE-III, THIAZOLE, ALTERNATIVE SPLICING, ATP- BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
2hfs:A (CYS260) to (GLN322) CRYSTAL STRUCTURE OF L. MAJOR MEVALONATE KINASE | GHMP KINASE, MEVALONATE KINASE, TRYPANOSOMATID PARASITE, TRANSFERASE
2hfs:B (CYS260) to (GLN322) CRYSTAL STRUCTURE OF L. MAJOR MEVALONATE KINASE | GHMP KINASE, MEVALONATE KINASE, TRYPANOSOMATID PARASITE, TRANSFERASE
2hfu:A (CYS260) to (GLN322) CRYSTAL STRUCTURE OF L. MAJOR MEVALONATE KINASE IN COMPLEX WITH R-MEVALONATE | GHMP KINASE, MEVALONATE KINASE, TRYPANOSOMATID PARASITE, TRANSFERASE
2hfu:B (CYS260) to (GLN322) CRYSTAL STRUCTURE OF L. MAJOR MEVALONATE KINASE IN COMPLEX WITH R-MEVALONATE | GHMP KINASE, MEVALONATE KINASE, TRYPANOSOMATID PARASITE, TRANSFERASE
1tu0:B (ILE25) to (ARG85) ASPARTATE TRANSCARBAMOYLASE CATALYTIC CHAIN MUTANT E50A COMPLEX WITH PHOSPHONOACETAMIDE | PROTEIN STRUCTURE-FUNCTION, SITE-SPECIFIC MUTAGENESIS, DOMAIN CLOSURE, ALLOSTERIC TRANSITION, HYDROLASE-HYDROLASE REGULATOR COMPLEX
3vqs:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vqs:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vqs:C (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vqs:D (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1tug:D (ILE25) to (ASN88) ASPARTATE TRANSCARBAMOYLASE CATALYTIC CHAIN MUTANT E50A COMPLEX WITH PHOSPHONOACETAMIDE, MALONATE, AND CYTIDINE-5- PRIME-TRIPHOSPHATE (CTP) | PROTEIN STRUCTURE-FUNCTION, SITE SPECIFIC MUTAGENESIS, DOMAIN CLOSURE, ALLOSTERIC TRANSITION, HYDROLASE/HYDROLASE REGULATOR COMPLEX
2hiq:A (LEU30) to (PHE93) CRYSTAL STRUCTURE OF JW1657 FROM ESCHERICHIA COLI | HYPOTHETICAL PROTEIN JW1657, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, SOUTHEAST COLLABORATORY FOR STRUCTURAL GENOMICS, SECSG, UNKNOWN FUNCTION
2hk2:A (GLN259) to (ASP317) CRYSTAL STRUCTURE OF MEVALONATE DIPHOSPHATE DECARBOXYLASE FROM STAPHYLOCOCCUS AUREUS (MONOCLINIC FORM) | MEVALONATE DIPHOSPHATE DECARBOXYLASE, DIPHOSPHOMEVALONATE DECARBOXYLASE, DECARBOXYLASE, LYASE
2hk2:B (GLN259) to (ASP317) CRYSTAL STRUCTURE OF MEVALONATE DIPHOSPHATE DECARBOXYLASE FROM STAPHYLOCOCCUS AUREUS (MONOCLINIC FORM) | MEVALONATE DIPHOSPHATE DECARBOXYLASE, DIPHOSPHOMEVALONATE DECARBOXYLASE, DECARBOXYLASE, LYASE
2hk3:A (GLN259) to (ASP317) CRYSTAL STRUCTURE OF MEVALONATE DIPHOSPHATE DECARBOXYLASE FROM STAPHYLOCOCCUS AUREUS (ORTHORHOMBIC FORM) | MEVALONATE DIPHOSPHATE DECARBOXYLASE, DIPHOSPHOMEVALONATE DECARBOXYLASE, DECARBOXYLASE, LYASE
2hk3:B (GLN259) to (ASP317) CRYSTAL STRUCTURE OF MEVALONATE DIPHOSPHATE DECARBOXYLASE FROM STAPHYLOCOCCUS AUREUS (ORTHORHOMBIC FORM) | MEVALONATE DIPHOSPHATE DECARBOXYLASE, DIPHOSPHOMEVALONATE DECARBOXYLASE, DECARBOXYLASE, LYASE
1hwu:D (LEU13) to (GLN98) STRUCTURE OF PII PROTEIN FROM HERBASPIRILLUM SEROPEDICAE | HERBASPIRILLUM SEROPEDICAE PII, BETA-ALPHA-BETA MOTIF, SIGNAL TRANSDUCTION PROTEIN, SIGNALING PROTEIN
4lq3:A (SER328) to (GLU383) CRYSTAL STRUCTURE OF HUMAN NOROVIRUS RNA-DEPENDENT RNA-POLYMERASE BOUND TO THE INHIBITOR PPNDS | RNA-DEPENDENT-RNA-POLYMERASE, RDRP-INHIBOTIR COMPLEX, VIRAL PROTEIN- REPLICATION INHIBITOR-RNA COMPLEX
4lq9:A (SER328) to (GLU383) CRYSTAL STRUCTURE OF HUMAN NOROVIRUS RNA-DEPENDENT RNA-POLYMERASE IN COMPLEX WITH NAF2 | RNA-DEPENDENT-RNA-POLYMERASE, RDRP-INHIBOTIR COMPLEX, VIRAL PROTEIN- REPLICATION INHIBITOR COMPLEX
4lt6:B (VAL399) to (HIS486) CRYSTAL STRUCTURE OF HUMAN POLY(A) POLYMERASE GAMMA | POLY(A) POLYMERASE, PAP, POLYMERASE, POLYADENYLATION, 3' PROCESSING, MRNA PROCESSING, NUCLEUS, TRANSFERASE
3w2v:A (THR638) to (ILE716) CRYSTAL STRUCTURE OF THE CMR2DHD-CMR3 SUBCOMPLEX BOUND TO 3'-AMP | FERREDOXIN-LIKE FOLD, IMMUNE SYSTEM
4lw2:C (ILE294) to (GLY355) STRUCTURAL CHANGES DURING CYSTEINE DESULFURASE CSDA AND SULFUR- ACCEPTOR CSDE INTERACTIONS PROVIDE INSIGHT INTO THE TRANS- PERSULFURATION | CYSTEINE DESULFURASE, CSDA, SUFS, LYASE
4lvs:A (GLU154) to (GLY231) DNA POLYMERASE BETA MISMATCHED SUBSTRATE COMPLEX WITH MN2+, 2.5 MIN | TRANSFERASE, LYASE/DNA POLYMERASE, LYASE-DNA COMPLEX
2hwh:A (THR287) to (TYR358) HCV NS5B ALLOSTERIC INHIBITOR COMPLEX | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE
2hwh:B (THR287) to (TYR358) HCV NS5B ALLOSTERIC INHIBITOR COMPLEX | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE
2hwi:A (THR287) to (TYR358) HCV NS5B ALLOSTERIC INHIBITOR COMPLEX | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE
2hwi:B (THR286) to (TYR358) HCV NS5B ALLOSTERIC INHIBITOR COMPLEX | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE
2wrm:A (THR287) to (TYR358) IDENTIFICATION OF NOVEL ALLOSTERIC INHIBITORS OF HEPATITIS C VIRUS NS5B POLYMERASE THUMB DOMAIN (SITE II) BY STRUCTURE-BASED DESIGN | TRANSFERASE, NON-NUCLEOSIDE INHIBITOR, NNI, VIRAL PROTEIN
1ua2:D (ARG57) to (GLU147) CRYSTAL STRUCTURE OF HUMAN CDK7 | CELL CYCLE; PHOSPHORYLATION; PROTEIN-PROTEIN INTERACTION; PROTEIN KINASE, CELL CYCLE, TRANSFERASE
4lzd:A (LEU291) to (HIS367) HUMAN DNA POLYMERASE MU- APOENZYME | POLYMERASE, DNA BREAK REPAIR, TRANSFERASE
4m04:A (LEU291) to (PHE389) HUMAN DNA POLYMERASE MU TERNARY COMPLEX | POLYMERASE, DNA BREAK REPAIR, TRANSFERASE-DNA COMPLEX
4m0a:A (LEU291) to (CYS390) HUMAN DNA POLYMERASE MU POST-CATALYTIC COMPLEX | POLYMERASE, DNA BREAK REPAIR, TRANSFERASE-DNA COMPLEX
2i1r:A (THR287) to (TYR358) NOVEL THIAZOLONES AS HCV NS5B POLYMERASE INHIBITORS: FURTHER DESIGNS, SYNTHESIS, SAR AND X-RAY COMPLEX STRUCTURE | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE
2i1r:B (THR286) to (TYR358) NOVEL THIAZOLONES AS HCV NS5B POLYMERASE INHIBITORS: FURTHER DESIGNS, SYNTHESIS, SAR AND X-RAY COMPLEX STRUCTURE | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE
4m1k:A (GLY618) to (PHE673) CRYSTAL STRUCTURE OF ELONGATION FACTOR G (EFG) | ELONGATION FACTOR G, TRANSLATION
5a6w:B (CYS202) to (LEU254) COMPLEX OF RICE BLAST (MAGNAPORTHE ORYZAE) EFFECTOR PROTEIN AVR-PIKD WITH THE HMA DOMAIN OF PIKP1 FROM RICE (ORYZA SATIVA) | ANTIVIRAL PROTEIN, RICE BLAST DISEASE, PLANT DISEASE RESISTANCE, EFFECTOR PROTEIN, INTEGRATED HMA DOMAIN
3j0k:B (PRO551) to (ARG617) ORIENTATION OF RNA POLYMERASE II WITHIN THE HUMAN VP16-MEDIATOR-POL II-TFIIF ASSEMBLY | TRANSFERASE-TRANSCRIPTION COMPLEX
1im4:A (LYS78) to (ALA146) CRYSTAL STRUCTURE OF A DINB HOMOLOG (DBH) LESION BYPASS DNA POLYMERASE CATALYTIC FRAGMENT FROM SULFOLOBUS SOLFATARICUS | DNA POLYMERASE PALM, THUMB, FINGERS, HELIX-HAIRPIN-HELIX, FIDELITY, PROCESSIVITY, TRANSFERASE
2ia6:A (LYS78) to (SER145) BYPASS OF MAJOR BENZOPYRENE-DG ADDUCT BY Y-FAMILY DNA POLYMERASE WITH UNIQUE STRUCTURAL GAP | BENZO PYRENE, CARCINOGEN, LESION BYPASS, POLYMERASE, TRANSLESION SYNTHESIS, DPO4, TRANSFERASE-DNA COMPLEX
2ia6:B (LYS78) to (SER145) BYPASS OF MAJOR BENZOPYRENE-DG ADDUCT BY Y-FAMILY DNA POLYMERASE WITH UNIQUE STRUCTURAL GAP | BENZO PYRENE, CARCINOGEN, LESION BYPASS, POLYMERASE, TRANSLESION SYNTHESIS, DPO4, TRANSFERASE-DNA COMPLEX
2ww4:A (ARG220) to (VAL269) A TRICLINIC CRYSTAL FORM OF E. COLI 4-DIPHOSPHOCYTIDYL-2C- METHYL-D-ERYTHRITOL KINASE | NON-MEVALONATE PATHWAY, ISOPRENOID BIOSYNTHESIS, KINASE, TRANSFERASE
2ww4:B (ARG220) to (VAL269) A TRICLINIC CRYSTAL FORM OF E. COLI 4-DIPHOSPHOCYTIDYL-2C- METHYL-D-ERYTHRITOL KINASE | NON-MEVALONATE PATHWAY, ISOPRENOID BIOSYNTHESIS, KINASE, TRANSFERASE
2ibk:A (LYS78) to (SER145) BYPASS OF MAJOR BENZOPYRENE-DG ADDUCT BY Y-FAMILY DNA POLYMERASE WITH UNIQUE STRUCTURAL GAP | BENZO PYRENE, CARCINOGEN, LESION BYPASS, POLYMERASE, TRANSLESION SYNTHESIS, DPO4, TRANSFERASE-DNA COMPLEX
2ide:A (LEU53) to (GLN139) CRYSTAL STRUCTURE OF THE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN C (TTHA1789) FROM THERMUS THEROMOPHILUS HB8 | MOAC, MOLYBDENUM COFACTOR (MOCO), MOCO BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, BIOSYNTHETIC PROTEIN
2ide:J (LEU53) to (GLN139) CRYSTAL STRUCTURE OF THE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN C (TTHA1789) FROM THERMUS THEROMOPHILUS HB8 | MOAC, MOLYBDENUM COFACTOR (MOCO), MOCO BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, BIOSYNTHETIC PROTEIN
3wc2:C (LEU48) to (ALA131) CRYSTAL STRUCTURE OF C. ALBICANS TRNA(HIS) GUANYLYLTRANSFERASE (THG1) WITH A TRNA(PHE)(GUG) | TRANSFERASE-RNA COMPLEX
1uu0:B (GLU249) to (ARG311) HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (HISC) FROM THERMOTOGA MARITIMA (APO-FORM) | HISTIDINE BIOSYNTHESIS, TRANSFERASE, AMINOTRANSFERASE, PYRIDOXAL PHOSPHATE, COMPLETE PROTEOME
1uut:A (GLN50) to (VAL136) THE NUCLEASE DOMAIN OF ADENO-ASSOCIATED VIRUS REP COMPLEXED WITH THE RBE' STEMLOOP OF THE VIRAL INVERTED TERMINAL REPEAT | HYDROLASE/DNA, NUCLEASE/COMPLEX, VIRAL PROTEIN, NUCLEASE, REPLICATION, PROTEIN-DNA, STEMLOOP, HELICASE
1uut:B (GLN50) to (VAL136) THE NUCLEASE DOMAIN OF ADENO-ASSOCIATED VIRUS REP COMPLEXED WITH THE RBE' STEMLOOP OF THE VIRAL INVERTED TERMINAL REPEAT | HYDROLASE/DNA, NUCLEASE/COMPLEX, VIRAL PROTEIN, NUCLEASE, REPLICATION, PROTEIN-DNA, STEMLOOP, HELICASE
2iih:A (ASP51) to (GLN139) CRYSTAL STRUCTURE OF THE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN C (TTHA1789) FROM THERMUS THEROMOPHILUS HB8 (H32 FORM) | MOAC, MOLYBDENUM COFACTOR (MOCO), MOCO BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, BIOSYNTHETIC PROTEIN
1ixm:B (ASP307) to (THR381) CRYSTAL STRUCTURE OF SPOOB FROM BACILLUS SUBTILIS | PHOSPHOTRANSFERASE, SPORULATION RESPONSE REGULATOR, TWO COMPONENT SYSTEM, REGULATORY PROTEIN
2ijn:A (THR287) to (TYR358) ISOTHIAZOLES AS ACTIVE-SITE INHIBITORS OF HCV NS5B POLYMERASE | HCV; NS5B; VIRAL RNA DIRECTED RNA POLYMERASE; RDRP; ACTIVE SITE; COVALENT INHIBITOR, TRANSCRIPTION,TRANSFERASE
2ijn:B (THR287) to (TYR358) ISOTHIAZOLES AS ACTIVE-SITE INHIBITORS OF HCV NS5B POLYMERASE | HCV; NS5B; VIRAL RNA DIRECTED RNA POLYMERASE; RDRP; ACTIVE SITE; COVALENT INHIBITOR, TRANSCRIPTION,TRANSFERASE
4mf8:A (ARG152) to (GLU232) STRUCTURE OF HUMAN DNA POLYMERASE BETA COMPLEXED WITH NICKED DNA CONTAINING A MISMATCHED TEMPLATE O6MG AND INCOMING CTP | DNA POLYMERASE X FAMILY, DNA SYNTHESIS, TRANSFERASE-DNA COMPLEX
2ipo:D (ILE25) to (ASN88) E. COLI ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH N- PHOSPHONACETYL-L-ASPARAGINE | ASPARTATE TRANSCARBAMOYLASE, ALLOSTERIC, INHIBITOR DESIGN, DOMAIN CLOSURE, TRANSFERASE
4mia:A (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH RG7109 (N-{4-[6-TERT-BUTYL-5-METHOXY-8-(6-METHOXY-2-OXO-2,5- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PHENYL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mia:B (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH RG7109 (N-{4-[6-TERT-BUTYL-5-METHOXY-8-(6-METHOXY-2-OXO-2,5- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PHENYL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mib:A (THR286) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH COMPOUND 48 (N-({(3S)-1-[6-TERT-BUTYL-5-METHOXY-8-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PYRROLIDIN-3-YL}METHYL) METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mib:B (THR286) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH COMPOUND 48 (N-({(3S)-1-[6-TERT-BUTYL-5-METHOXY-8-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PYRROLIDIN-3-YL}METHYL) METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1v3s:A (LEU13) to (PRO95) CRYSTAL STRUCTURE OF TT1020 FROM THERMUS THERMOPHILUS HB8 | STRUCTURAL GENOMICS, SIGNAL TRANSDUCING PROTEIN, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, SIGNALING PROTEIN
1j5w:A (TYR2) to (VAL111) CRYSTAL STRUCTURE OF GLYCYL-TRNA SYNTHETASE ALPHA CHAIN (TM0216) FROM THERMOTOGA MARITIMA AT 1.95 A RESOLUTION | STRUCTURAL GENOMICS, TM0216, JCSG, GLYCYL-TRNA SYNTHETASE ALPHA CHAIN, PSI, PROTEIN STRUCTURE INITIATIVE, JOINT CENTER FOR STRUCTURAL GENOMICS, LIGASE
2x7i:A (LYS247) to (GLY305) CRYSTAL STRUCTURE OF MEVALONATE KINASE FROM METHICILLIN- RESISTANT STAPHYLOCOCCUS AUREUS MRSA252 | KINASE, TRANSFERASE
4mk7:A (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 2 (3-(3-TERT-BUTYL-4-METHOXYPHENYL)PYRIDIN-2(1H)-ONE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk7:B (THR286) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 2 (3-(3-TERT-BUTYL-4-METHOXYPHENYL)PYRIDIN-2(1H)-ONE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk8:A (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 4 (N-(4-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]ETHYL}PHENYL)METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk8:B (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 4 (N-(4-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]ETHYL}PHENYL)METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk9:A (THR286) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 12 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk9:B (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 12 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mka:A (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 13 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mka:B (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 13 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mkb:A (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 14 (N-(4-{(E)-2-[3-TERT-BUTYL-2-METHOXY-5-(3-OXO-2,3- DIHYDROPYRIDAZIN-4-YL)PHENYL]ETHENYL}PHENYL)METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mkb:B (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 14 (N-(4-{(E)-2-[3-TERT-BUTYL-2-METHOXY-5-(3-OXO-2,3- DIHYDROPYRIDAZIN-4-YL)PHENYL]ETHENYL}PHENYL)METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5amq:A (ASN1149) to (ASN1233) STRUCTURE OF THE LA CROSSE BUNYAVIRUS POLYMERASE IN COMPLEX WITH THE 3' AND 5' VIRAL RNA | HYDROLASE, POLYMERASE, RNADRNAPOL, BUNYAVIRUS, RNA
5amr:A (TYR1150) to (ASN1233) STRUCTURE OF THE LA CROSSE BUNYAVIRUS POLYMERASE IN COMPLEX WITH THE 3' VIRAL RNA | HYDROLASE, POLYMERASE, RNADRNAPOL, BUNYAVIRUS, RNA
2xc9:A (GLU79) to (SER145) BINARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE AND 1,N2-ETHENOGUANINE MODIFIED DNA, MAGNESIUM FORM | TRANSFERASE-DNA COMPLEX, TRANSLESION NUCLEOTIDYLTRANSFERASE
2xca:A (LYS78) to (SER145) TERNARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE, 7,8-DIHYDRO-8-OXODEOXYGUANINE MODIFIED DNA AND DGTP - MAGNESIUM FORM | TRANSFERASE-DNA COMPLEX, TRANSLESION NUCLEOTIDYLTRANSFERASE
2xcp:A (LYS78) to (SER145) TERNARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE, 7,8-DIHYDRO-8-OXODEOXYGUANINE MODIFIED DNA AND DCTP - MAGNESIUM FORM | DNA-TRANSFERASE COMPLEX, TRANSLESION DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSFERASE
2xcp:B (LYS78) to (SER145) TERNARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE, 7,8-DIHYDRO-8-OXODEOXYGUANINE MODIFIED DNA AND DCTP - MAGNESIUM FORM | DNA-TRANSFERASE COMPLEX, TRANSLESION DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSFERASE
1jk9:D (CYS20) to (GLY74) HETERODIMER BETWEEN H48F-YSOD1 AND YCCS | PROTEIN-PROTEIN COMPLEX, HETERODIMER, METALLOCHAPERONE, CHAPERONE, COPPER, AMYOTROPHIC LATERAL SCLEROSIS, LOU GEHRIG'S DISEASE, OXIDOREDUCTASE
2j3r:B (LYS81) to (VAL162) THE CRYSTAL STRUCTURE OF THE BET3-TRS31 HETERODIMER. | GOLGI APPARATUS, VESICLE TRANSPORT, ER-GOLGI TRANSPORT, TRAPP, PALMITATE, TRANSPORT, LIPOPROTEIN, ENDOPLASMIC RETICULUM, MULTISUBUNIT TETHERING FACTOR
2j3t:A (ASP70) to (PHE150) THE CRYSTAL STRUCTURE OF THE BET3-TRS33-BET5-TRS23 COMPLEX. | TRAPP, PALMITATE, TRANSPORT, LIPOPROTEIN, ER-GOLGI TRANSPORT, GOLGI APPARATUS, PROTEIN TRANSPORT, VESICLE TRANSPORT, ENDOPLASMIC RETICULUM, MULTISUBUNIT TETHERING FACTOR
2j3w:D (PHE71) to (PHE150) THE CRYSTAL STRUCTURE OF THE BET3-TRS31-SEDLIN COMPLEX. | MULTISUBUNIT TETHERING FACTOR, TRAPP, PALMITATE, TRANSPORT, LIPOPROTEIN, ER-GOLGI TRANSPORT, ENDOPLASMIC RETICULUM, TRANSCRIPTION, GOLGI APPARATUS, VESICLE TRANSPORT
2j3w:E (PHE71) to (PHE150) THE CRYSTAL STRUCTURE OF THE BET3-TRS31-SEDLIN COMPLEX. | MULTISUBUNIT TETHERING FACTOR, TRAPP, PALMITATE, TRANSPORT, LIPOPROTEIN, ER-GOLGI TRANSPORT, ENDOPLASMIC RETICULUM, TRANSCRIPTION, GOLGI APPARATUS, VESICLE TRANSPORT
2j3w:F (LYS81) to (VAL162) THE CRYSTAL STRUCTURE OF THE BET3-TRS31-SEDLIN COMPLEX. | MULTISUBUNIT TETHERING FACTOR, TRAPP, PALMITATE, TRANSPORT, LIPOPROTEIN, ER-GOLGI TRANSPORT, ENDOPLASMIC RETICULUM, TRANSCRIPTION, GOLGI APPARATUS, VESICLE TRANSPORT
3wrc:B (ASP96) to (GLY186) CRYSTAL STRUCTURE OF THE ANAEROBIC DESB-PROTOCATECHUATE (PCA) COMPLEX | OXIDOREDUCTASE, EXTRADIOL DIOXYGENASE, FE2+ BINDING, DOMAIN-SWAP DIMER
1jms:A (ASN304) to (GLU386) CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF MURINE TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE | POLYMERASE, NUCLEOTIDYL TRANSFERASE
1jmt:A (ASP63) to (LEU144) X-RAY STRUCTURE OF A CORE U2AF65/U2AF35 HETERODIMER | RRM, RNA SPLICING, PROLINE, PPII HELIX, PEPTIDE RECOGNITION, RNA BINDING PROTEIN
3wsd:A (GLY112) to (LYS165) OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsd:B (GLY112) to (LYS165) OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsd:D (GLY112) to (LYS165) OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsd:E (GLY112) to (LYS165) OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsd:F (GLY112) to (LYS165) OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wse:A (GLY112) to (LYS165) REDUCED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wse:B (GLY112) to (LYS165) REDUCED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wse:C (GLY112) to (LYS165) REDUCED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wse:E (GLY112) to (LYS165) REDUCED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsf:A (GLY112) to (LYS165) OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII WITH CITRATE | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsf:B (GLY112) to (LYS165) OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII WITH CITRATE | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsf:D (GLY112) to (LYS165) OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII WITH CITRATE | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsf:E (GLY112) to (LYS165) OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII WITH CITRATE | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsf:F (GLY112) to (LYS165) OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII WITH CITRATE | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsg:A (GLY112) to (LYS165) REDUCED HCGD FROM METHANOCALDOCOCCUS JANNASCHII WITH CITRATE | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsg:B (GLY112) to (LYS165) REDUCED HCGD FROM METHANOCALDOCOCCUS JANNASCHII WITH CITRATE | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsg:C (GLY112) to (LYS165) REDUCED HCGD FROM METHANOCALDOCOCCUS JANNASCHII WITH CITRATE | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsg:E (GLY112) to (LYS165) REDUCED HCGD FROM METHANOCALDOCOCCUS JANNASCHII WITH CITRATE | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsg:F (GLY112) to (LYS165) REDUCED HCGD FROM METHANOCALDOCOCCUS JANNASCHII WITH CITRATE | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsh:A (GLY112) to (LYS165) EDTA-TREATED, OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsh:B (GLY112) to (LYS165) EDTA-TREATED, OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsh:C (GLY112) to (LYS165) EDTA-TREATED, OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsh:D (GLY112) to (LYS165) EDTA-TREATED, OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsh:E (GLY112) to (LYS165) EDTA-TREATED, OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsh:F (GLY112) to (LYS165) EDTA-TREATED, OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsh:G (GLY112) to (LYS165) EDTA-TREATED, OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsh:H (GLY112) to (LYS165) EDTA-TREATED, OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsh:I (GLY112) to (LYS165) EDTA-TREATED, OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsh:J (GLY112) to (LYS165) EDTA-TREATED, OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsh:K (GLY112) to (LYS165) EDTA-TREATED, OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsh:L (GLY112) to (LYS165) EDTA-TREATED, OXIDIZED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsi:A (GLY112) to (LYS165) EDTA-TREATED, REDUCED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsi:B (GLY112) to (LYS165) EDTA-TREATED, REDUCED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsi:E (GLY112) to (LYS165) EDTA-TREATED, REDUCED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
3wsi:F (GLY112) to (LYS165) EDTA-TREATED, REDUCED HCGD FROM METHANOCALDOCOCCUS JANNASCHII | NIF3-RELATED PROTEIN, METAL BINDING PROTEIN
2xhu:A (THR286) to (TYR358) HCV-J4 NS5B POLYMERASE ORTHORHOMBIC CRYSTAL FORM | REPLICATION, TRANSCRIPTION, TRANSFERASE
2xhu:B (THR287) to (TYR358) HCV-J4 NS5B POLYMERASE ORTHORHOMBIC CRYSTAL FORM | REPLICATION, TRANSCRIPTION, TRANSFERASE
2j6s:A (GLU79) to (SER145) TERNARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE, O6-METHYLGUANINE MODIFIED DNA, AND DATP. | TRANSFERASE/DNA, TRANSFERASE/DNA COMPLEX, MUTATOR PROTEIN, DNA REPLICATION, O6-METHYLGUANINE, TRANSFERASE, METAL-BINDING, DNA POLYMERASE, TRANSLESION DNA SYNTHESIS, DNA-DIRECTED DNA POLYMERASE, DPO4, MAGNESIUM, DNA REPAIR, DNA DAMAGE, DNA-BINDING, NUCLEOTIDYLTRANSFERASE, SULFOLOBUS SOLFATARICUS
2j6t:A (LYS78) to (SER145) TERNARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE, O6-METHYLGUANINE MODIFIED DNA, AND DATP. | TRANSFERASE-DNA COMPLEX, MUTATOR PROTEIN, DNA REPLICATION, O6-METHYLGUANINE, TRANSFERASE, METAL-BINDING, TRANSLESION DNA SYNTHESIS, DNA-DIRECTED DNA POLYMERASE, DPO4, DNA REPAIR, DNA DAMAGE, DNA-BINDING, NUCLEOTIDYLTRANSFERASE
2j6u:A (GLU82) to (SER148) TERNARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE, O6-METHYLGUANINE MODIFIED DNA, AND DGTP. | TRANSFERASE/DNA, TRANSFERASE/DNA COMPLEX, MUTATOR PROTEIN, DNA REPLICATION, O6-METHYLGUANINE, TRANSFERASE, METAL-BINDING, DNA POLYMERASE, TRANSLESION DNA SYNTHESIS, DNA-DIRECTED DNA POLYMERASE, DPO4, MAGNESIUM, DNA REPAIR, DNA DAMAGE, DNA-BINDING, NUCLEOTIDYLTRANSFERASE, SULFOLOBUS SOLFATARICUS
2xhw:A (SER288) to (TYR358) HCV-J4 NS5B POLYMERASE TRIGONAL CRYSTAL FORM | REPLICATION, TRANSCRIPTION, TRANSFERASE
2xi2:A (THR287) to (TYR358) HCV-H77 NS5B APO POLYMERASE | TRANSFERASE, NONSTRUCTURAL PROTEIN, REPLICATION, RDRP, DE NOVO PRIMING
2xi2:B (THR287) to (TYR358) HCV-H77 NS5B APO POLYMERASE | TRANSFERASE, NONSTRUCTURAL PROTEIN, REPLICATION, RDRP, DE NOVO PRIMING
2xi2:C (THR287) to (TYR358) HCV-H77 NS5B APO POLYMERASE | TRANSFERASE, NONSTRUCTURAL PROTEIN, REPLICATION, RDRP, DE NOVO PRIMING
2xi3:A (THR287) to (TYR358) HCV-H77 NS5B POLYMERASE COMPLEXED WITH GTP | TRANSFERASE, NONSTRUCTURAL PROTEIN, REPLICATION, RDRP, DE NOVO PRIMING, HEPACIVIRUS
2xi3:B (THR287) to (TYR358) HCV-H77 NS5B POLYMERASE COMPLEXED WITH GTP | TRANSFERASE, NONSTRUCTURAL PROTEIN, REPLICATION, RDRP, DE NOVO PRIMING, HEPACIVIRUS
2j7k:A (MET617) to (PHE673) CRYSTAL STRUCTURE OF THE T84A MUTANT EF-G:GDPCP COMPLEX | ELONGATION FACTOR, NUCLEOTIDE-BINDING, P-LOOP, THR84ALA, MUTATION, GTP-BINDING, TRANSLATION, NUCLEOTIDE- BINDING, PROTEIN BIOSYNTHESIS
2xk1:D (ARG1) to (GLU76) CRYSTAL STRUCTURE OF A COMPLEX BETWEEN ACTINOMADURA R39 DD- PEPTIDASE AND A BORONATE INHIBITOR | HYDROLASE, PEPTIDOGLYCAN
5axk:B (LYS40) to (ALA117) CRYSTAL STRUCTURE OF THG1 LIKE PROTEIN (TLP) | TRANSFERASE
5axl:A (THR41) to (ALA117) CRYSTAL STRUCTURE OF THG1 LIKE PROTEIN (TLP) WITH GTP | TRANSFERASE
1jxe:A (LYS738) to (GLY824) STOFFEL FRAGMENT OF TAQ DNA POLYMERASE I | NUCLEOTIDYLTRANSFERASE, DNA-DIRECTED DNA POLYMERASE, DNA REPLICATION
1w1j:A (SER17) to (SER101) STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE: THE505SER MUTANT | FLAVOENZYME, OXIDOREDUCTASE, CATALYSIS, FAD
1w1j:B (LEU18) to (SER101) STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE: THE505SER MUTANT | FLAVOENZYME, OXIDOREDUCTASE, CATALYSIS, FAD
1w1l:A (SER17) to (SER101) STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE: PHE454TYR MUTANT | OXIDOREDUCTASE, FLAVOENZYME, OXIDASE, CATALYSIS
1w1m:A (SER17) to (SER101) STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE: GLU502GLY MUTANT | FLAVOENZYME, OXIDOREDUCTASE, CATALYSIS, FAD
2jc0:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB655264 | HEPATITIS, POLYMERASE, HYDROLASE
2jc0:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB655264 | HEPATITIS, POLYMERASE, HYDROLASE
2jc1:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB698223 | HEPATITIS, POLYMERASE, HYDROLASE
4n3o:B (GLU276) to (ASP326) 2.4 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF PUTATIVE SUGAR KINASE FROM CAMPYLOBACTER JEJUNI. | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, TRANSFERASE
2jei:A (GLU79) to (SER145) THE MOLECULAR BASIS OF SELECTIVITY OF NUCLEOSIDE TRIPHOSPHATE INCORPORATION OPPOSITE O6-BENZYLGUANINE BY SULFOLOBUS SOLFATARICUS DNA POLYMERASE IV: STEADY-STATE AND PRE-STEADY-STATE KINETICS AND X-RAY CRYSTALLOGRAPHY OF CORRECT AND INCORRECT PAIRING | DNA REPLICATION, MUTATOR PROTEIN, 06-BENZYLGUANINE, NUCLEOTIDYLTRANSFERASE, DNA-DIRECTED DNA POLYMERASE, DPO4, MAGNESIUM, POLYMERASE, DNA DAMAGE, DNA REPAIR, ALKYLATING AGENTS, TRANSLESION SYNTHESIS, TRANSFERASE, DNA-BINDING, METAL-BINDING
2jeg:A (LYS78) to (SER145) THE MOLECULAR BASIS OF SELECTIVITY OF NUCLEOSIDE TRIPHOSPHATE INCORPORATION OPPOSITE O6-BENZYLGUANINE BY SULFOLOBUS SOLFATARICUS DNA POLYMERASE IV: STEADY-STATE AND PRE-STEADY-STATE KINETICS AND X-RAY CRYSTALLOGRAPHY OF CORRECT AND INCORRECT PAIRING | DNA REPLICATION, MUTATOR PROTEIN, 06-BENZYLGUANINE, NUCLEOTIDYLTRANSFERASE, DNA-DIRECTED DNA POLYMERASE, DPO4, MAGNESIUM, POLYMERASE, DNA DAMAGE, DNA REPAIR, ALKYLATING AGENTS, TRANSLESION SYNTHESIS, TRANSFERASE, DNA-BINDING, METAL-BINDING
2jej:A (LYS78) to (SER145) THE MOLECULAR BASIS OF SELECTIVITY OF NUCLEOSIDE TRIPHOSPHATE INCORPORATION OPPOSITE O6-BENZYLGUANINE BY SULFOLOBUS SOLFATARICUS DNA POLYMERASE IV: STEADY-STATE AND PRE-STEADY-STATE KINETICS AND X-RAY CRYSTALLOGRAPHY OF CORRECT AND INCORRECT PAIRING | DNA REPLICATION, MUTATOR PROTEIN, 06-BENZYLGUANINE, NUCLEOTIDYLTRANSFERASE, DNA-DIRECTED DNA POLYMERASE, DPO4, MAGNESIUM, POLYMERASE, DNA DAMAGE, DNA REPAIR, ALKYLATING AGENTS, TRANSLESION SYNTHESIS, TRANSFERASE, DNA-BINDING, METAL-BINDING
1w7h:A (SER61) to (GLU160) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH SMALL MOLECULE INHIBITOR | P38, KINASE, INHIBITOR COMPLEX, PHOSPHORYLATION, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
2xul:C (LEU13) to (GLN98) STRUCTURE OF PII FROM SYNECHOCOCCUS ELONGATUS IN COMPLEX WITH 2-OXOGLUTARATE AT HIGH 2-OG CONCENTRATIONS | SIGNALING PROTEIN, GLNK
2xul:E (LEU13) to (GLN98) STRUCTURE OF PII FROM SYNECHOCOCCUS ELONGATUS IN COMPLEX WITH 2-OXOGLUTARATE AT HIGH 2-OG CONCENTRATIONS | SIGNALING PROTEIN, GLNK
2jhe:D (LEU13) to (THR69) N-TERMINAL DOMAIN OF TYRR TRANSCRIPTION FACTOR (RESIDUES 1 - 190) | TRANSCRIPTION, AROMATIC HYDROCARBONS CATABOLISM, TYRR PROTEIN, NUCLEOTIDE-BINDING, TRANSCRIPTION REGULATION, ACTIVATOR, REPRESSOR, ATP-BINDING, DNA-BINDING, TWO-COMPONENT REGULATORY SYSTEM
1w84:A (SER61) to (GLU160) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH SMALL MOLECULE INHIBITOR | KINASE/INHIBITOR, KINASE/INHIBITOR COMPLEX, P38, KINASE, INHIBITOR COMPLEX
1k1q:A (LYS78) to (ALA146) CRYSTAL STRUCTURE OF A DINB FAMILY ERROR PRONE DNA POLYMERASE FROM SULFOLOBUS SOLFATARICUS | DNA POLYMERASE, ERROR-PRONE POLYMERASE, LESION-BYPASS POLYMERASE, TRANSCRIPTION
1k1s:A (LYS78) to (ALA146) CRYSTAL STRUCTURE OF DINB FROM SULFOLOBUS SOLFATARICUS | MIXED A/B STRUCTURE, 4-STRANDED ANTIPARALLEL B-SHEET, TRANSCRIPTION
2xwh:A (THR287) to (TYR358) HCV-J6 NS5B POLYMERASE STRUCTURE AT 1.8 ANGSTROM | TRANSFERASE, REPLICATION
4nas:D (LEU25) to (PRO115) THE CRYSTAL STRUCTURE OF A RUBISCO-LIKE PROTEIN (MTNW) FROM ALICYCLOBACILLUS ACIDOCALDARIUS SUBSP. ACIDOCALDARIUS DSM 446 | STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, LYASE
2xxd:A (SER288) to (TYR358) HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 1.9 ANGSTROM | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
1wbn:A (SER61) to (GLU160) FRAGMENT BASED P38 INHIBITORS | P38 MAP KINASE, INHIBITOR STRUCTURE, ALTERNATIVE SPLICING, ATP-BINDING, NUCLEAR PROTEIN, PHOSPHORYLATION, SERINE/THREONINE PROTEIN KINASE, TRANSFERASE
1wbo:A (SER61) to (GLU160) FRAGMENT BASED P38 INHIBITORS | TRANSFERASE, ATP-BINDING, DIRECT PROTEIN SEQUENCING, NUCLEAR PROTEIN, PHOSPHORYLATION, SERINE/THREONINE-PROTEIN KINASE, 38 MAP KINASE, INHIBITOR STRUCTURE
1wbs:A (SER61) to (GLU160) IDENTIFICATION OF NOVEL P38 ALPHA MAP KINASE INHIBITORS USING FRAGMENT-BASED LEAD GENERATION. | P38, MAP KINASE, INHIBITOR STRUCTURE, ALTERNATIVE SPLICING, ATP-BINDING, NUCLEAR PROTEIN, PHOSPHORYLATION, SERINE/THREONINE PROTEIN KINASE, TRANSFERASE
1wbv:A (SER61) to (GLU160) IDENTIFICATION OF NOVEL P38 ALPHA MAP KINASE INHIBITORS USING FRAGMENT-BASED LEAD GENERATION. | P38, MAP KINASE, INHIBITOR STRUCTURE, ALTERNATIVE SPLICING, ATP-BINDING, NUCLEAR PROTEIN, PHOSPHORYLATION, SERINE/THREONINE PROTEIN KINASE, TRANSFERASE
1wc8:A (ASP70) to (PHE150) THE CRYSTAL STRUCTURE OF MOUSE BET3P | VESICLE TRANSPORT, TETHERING FACTOR, TRAPP, TRANSPORT PROTEIN, GOLGI STACK, ENDOPLASMIC RETICULUM
2xym:A (THR287) to (TYR358) HCV-JFH1 NS5B T385A MUTANT | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
4ndv:B (SER15) to (GLU78) CRYSTAL STRUCTURE OF L. DECASTES ALPHA-GALACTOSYL-BINDING LECTIN IN COMPLEX WITH GLOBOTRIOSE | LECTIN, SUGAR BINDING PROTEIN
2xzw:B (LEU13) to (GLN98) STRUCTURE OF PII FROM SYNECHOCOCCUS ELONGATUS IN COMPLEX WITH 2-OXOGLUTARATE AT LOW 2-OG CONCENTRATIONS | SIGNALING PROTEIN
1wd6:B (LEU23) to (PHE86) CRYSTAL STRUCTURE OF JW1657 FROM ESCHERICHIA COLI | HYPOTHETICAL PROTEIN, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, UNKNOWN FUNCTION
3zkb:I (GLU188) to (GLY282) CRYSTAL STRUCTURE OF THE ATPASE REGION OF MYCOBACTERIUM TUBERCULOSIS GYRB WITH AMPPNP | ISOMERASE, TYPE IIA TOPOISOMERASE, GHKL DOMAIN
3zkb:P (ASP186) to (THR283) CRYSTAL STRUCTURE OF THE ATPASE REGION OF MYCOBACTERIUM TUBERCULOSIS GYRB WITH AMPPNP | ISOMERASE, TYPE IIA TOPOISOMERASE, GHKL DOMAIN
3zkd:E (ASP186) to (THR283) CRYSTAL STRUCTURE OF THE ATPASE REGION OF MYCOBACTERIUM TUBERCULOSIS GYRB WITH AMPPNP | ISOMERASE, GHKL DOMAIN
1wle:A (GLY249) to (ALA297) CRYSTAL STRUCTURE OF MAMMALIAN MITOCHONDRIAL SERYL-TRNA SYNTHETASE COMPLEXED WITH SERYL-ADENYLATE | LIGASE
4nkr:C (ASP63) to (GLU109) THE CRYSTAL STRUCTURE OF BACILLUS SUBTILIS MOBB | P-LOOP, WALKER A MOTIF, NUCLEOTIDE BINDING, GTP, PHOSPHATE BINDING, CYTOSOL, UNKNOWN FUNCTION
2kn4:A (PRO84) to (GLN145) THE STRUCTURE OF THE RRM DOMAIN OF SC35 | RRM DOMAIN, CELL WALL, IGG-BINDING PROTEIN, PEPTIDOGLYCAN-ANCHOR, SECRETED, MRNA PROCESSING, MRNA SPLICING, NUCLEUS, PHOSPHOPROTEIN, RNA-BINDING, RNA BINDING PROTEIN
4nld:A (GLY283) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH BMS-791325 ALSO KNOWN AS (1AR,12BS)-8- CYCLOHEXYL-N-(DIMETHYLSULFAMOYL)-11-METHOXY-1A-{[(1R,5S)-3-METHYL-3, 8-DIAZABICYCLO[3.2.1]OCT-8-YL]CARBONYL}-1,1A,2,12B- TETRAHYDROCYCLOPROPA[D]INDOLO[2,1-A][2]BENZAZEPINE-5-CARBOXAMIDE AND 2-(4-FLUOROPHENYL)-N-METHYL-6-[(METHYLSULFONYL)AMINO]-5-(PROPAN-2- YLOXY)-1-BENZOFURAN-3-CARBOXAMIDE | NS5B, POLYMERASE, HCV, HEPATITIS C VIRUS, FINGERS, PALM, THUMB, TRANSFERASE/TRANSFERASE INHIBITOR, POLYMERASE/POLYMERASE INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4nlg:A (LYS78) to (ALA146) Y-FAMILY DNA POLYMERASE CHIMERA DBH-DPO4(243-245)-DBH | TRANSLESION SYNTHESIS, TRANSFERASE-DNA COMPLEX
4nlp:A (THR293) to (ALA380) POLIOVIRUS POLYMERASE - C290V LOOP MUTANT | POLYMERASE, RNA DEPENDENT RNA POLYMERASE, RDRP, VIRUS, VIRAL PROTEIN, HYDROLASE
4nlx:A (THR293) to (PRO356) POLIOVIRUS POLYMERASE - G289A/C290V LOOP MUTANT | POLYMERASE, RNA DEPENDENT RNA POLYMERASE, RDRP, VIRUS, VIRAL PROTEIN, HYDROLASE
5c16:A (LYS272) to (ALA342) MYOTUBULARIN-RELATED PROETIN 1 | MTMR, PHOSPHATASE, HYDROLASE
5c16:B (LYS272) to (ALA342) MYOTUBULARIN-RELATED PROETIN 1 | MTMR, PHOSPHATASE, HYDROLASE
5c16:C (LYS272) to (ALA342) MYOTUBULARIN-RELATED PROETIN 1 | MTMR, PHOSPHATASE, HYDROLASE
5c16:D (LYS272) to (ALA342) MYOTUBULARIN-RELATED PROETIN 1 | MTMR, PHOSPHATASE, HYDROLASE
3zph:C (ARG22) to (LEU140) BACTERIAL CHALCONE ISOMERASE IN CLOSED CONFORMATION FROM EUBACTERIUM RAMULUS AT 2.8 A RESOLUTION | ISOMERASE, FLAVONOID DEGRADATION
3zph:F (SER18) to (LEU140) BACTERIAL CHALCONE ISOMERASE IN CLOSED CONFORMATION FROM EUBACTERIUM RAMULUS AT 2.8 A RESOLUTION | ISOMERASE, FLAVONOID DEGRADATION
1wuu:A (CYS322) to (LEU380) CRYSTAL STRUCTURE OF HUMAN GALACTOKINASE COMPLEXED WITH MGAMPPNP AND GALACTOSE | GALACTOSEMIA, GHMP SUPERFAMILY, KINASE, TRANSFERASE
1wuu:B (PRO323) to (LEU380) CRYSTAL STRUCTURE OF HUMAN GALACTOKINASE COMPLEXED WITH MGAMPPNP AND GALACTOSE | GALACTOSEMIA, GHMP SUPERFAMILY, KINASE, TRANSFERASE
1wuu:C (CYS322) to (LEU380) CRYSTAL STRUCTURE OF HUMAN GALACTOKINASE COMPLEXED WITH MGAMPPNP AND GALACTOSE | GALACTOSEMIA, GHMP SUPERFAMILY, KINASE, TRANSFERASE
1wuu:D (CYS322) to (LEU380) CRYSTAL STRUCTURE OF HUMAN GALACTOKINASE COMPLEXED WITH MGAMPPNP AND GALACTOSE | GALACTOSEMIA, GHMP SUPERFAMILY, KINASE, TRANSFERASE
1kij:A (SER185) to (GLY248) CRYSTAL STRUCTURE OF THE 43K ATPASE DOMAIN OF THERMUS THERMOPHILUS GYRASE B IN COMPLEX WITH NOVOBIOCIN | TOPOISOMERASE, GYRASE B-COUMARIN COMPLEX, ISOMERASE
2lgs:A (ALA188) to (PHE255) FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | LIGASE(AMIDE SYNTHETASE)
2lgs:B (ALA188) to (PHE255) FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | LIGASE(AMIDE SYNTHETASE)
2lgs:C (ALA188) to (PHE255) FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | LIGASE(AMIDE SYNTHETASE)
2lgs:D (ALA188) to (PHE255) FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | LIGASE(AMIDE SYNTHETASE)
2lgs:E (ALA188) to (PHE255) FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | LIGASE(AMIDE SYNTHETASE)
2lgs:F (ALA188) to (PHE255) FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | LIGASE(AMIDE SYNTHETASE)
2lgs:G (ALA188) to (PHE255) FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | LIGASE(AMIDE SYNTHETASE)
2lgs:H (ALA188) to (PHE255) FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | LIGASE(AMIDE SYNTHETASE)
2lgs:I (ALA188) to (PHE255) FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | LIGASE(AMIDE SYNTHETASE)
2lgs:J (ALA188) to (PHE255) FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | LIGASE(AMIDE SYNTHETASE)
2lgs:K (ALA188) to (PHE255) FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | LIGASE(AMIDE SYNTHETASE)
2lgs:L (ALA188) to (PHE255) FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | LIGASE(AMIDE SYNTHETASE)
3zsg:A (SER61) to (GLU160) X-RAY STRUCTURE OF P38ALPHA BOUND TO TAK-715 | TRANSFERASE
2m0g:B (ASP391) to (LYS462) STRUCTURE, PHOSPHORYLATION AND U2AF65 BINDING OF THE NTERMINAL DOMAIN OF SPLICING FACTOR 1 DURING 3 SPLICE SITE RECOGNITION | SPLICEOSOME ASSEMBLY, SF1, UHM, ULM, SPLICING
5c51:A (MET1093) to (ASP1186) PROBING THE STRUCTURAL AND MOLECULAR BASIS OF NUCLEOTIDE SELECTIVITY BY HUMAN MITOCHONDRIAL DNA POLYMERASE GAMMA | NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIS), HIV RT, HUMAN MITOCHONDRIAL DNA POLYMERASE, MITOCHONDRIAL TOXICITY, DRUG EFFICACY AND TOXICITY, TRANSFERASE-DNA COMPLEX
5c52:A (MET1093) to (ASP1186) PROBING THE STRUCTURAL AND MOLECULAR BASIS OF NUCLEOTIDE SELECTIVITY BY HUMAN MITOCHONDRIAL DNA POLYMERASE GAMMA | NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIS), HIV REVERSE TRANSCRIPTASE (RT), HUMAN MITOCHONDRIAL DNA POLYMERASE, TRANSFERASE- DNA COMPLEX
5c53:A (MET1093) to (ASP1186) PROBING THE STRUCTURAL AND MOLECULAR BASIS OF NUCLEOTIDE SELECTIVITY BY HUMAN MITOCHONDRIAL DNA POLYMERASE GAMMA | NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIS), HIV REVERSE TRANSCRIPTASE (RT), HUMAN MITOCHONDRIAL DNA POLYMERASE, MITOCHONDRIAL TOXICITY, DRUG EFFICACY AND TOXICITY, TRANSFERASE, TRANSFERASE-DNA COMPLEX
2mqp:A (CYS212) to (TYR264) STRUCTURAL INVESTIGATION OF HNRNP L BOUND TO RNA | PROTEIN-RNA COMPLEX, RRM, RNA BINDING PROTEIN-RNA COMPLEX
5c5j:F (PHE76) to (ALA143) POYMERASE NUCLEOTIDE COMPLEX | DNA POLYMERASE, REPLICATION, TRANSFERASE-DNA COMPLEX
5c5j:A (ASP77) to (PRO144) POYMERASE NUCLEOTIDE COMPLEX | DNA POLYMERASE, REPLICATION, TRANSFERASE-DNA COMPLEX
1ktq:A (LYS738) to (GLY824) DNA POLYMERASE | NUCLEOTIDYLTRANSFERASE, DNA-REPLICATION
1kv1:A (SER61) to (GLU160) P38 MAP KINASE IN COMPLEX WITH INHIBITOR 1 | PROTEIN-INHIBITOR COMPLEX, TRANSFERASE
1kvk:A (HIS312) to (GLU369) THE STRUCTURE OF BINARY COMPLEX BETWEEN A MAMMALIAN MEVALONATE KINASE AND ATP: INSIGHTS INTO THE REACTION MECHANISM AND HUMAN INHERITED DISEASE | RMK, ATP, GHMP, TRANSFERASE
4nz0:C (ALA297) to (LYS386) THE EMCV 3DPOL STRUCTURE AT 2.8A RESOLUTION | ENCEPHALOMYOCARDITIS VIRUS, CLOSE RIGHT HAND, RNA DEPENDENT RNA POLYMERASE, TRANSFERASE
5c9i:B (LEU376) to (ASP442) STRUCTURE OF N-ACYLHOMOSERINE LACTONE ACYLASE MACQ SHORTENED SPACER MUTANT (DELTA202-208) IN UNCLEAVED FORM | ACYLASE, NTN-HYDROLASE FOLD, HYDROLASE
2yis:A (SER61) to (GLU160) TRIAZOLOPYRIDINE INHIBITORS OF P38 KINASE. | TRANSFERASE, INHIBITOR SBDD KINASE, CELL CYCLE
2yiw:A (SER61) to (GLU160) TRIAZOLOPYRIDINE INHIBITORS OF P38 KINASE | TRANSFERASE, INHIBITOR SBDD KINASE, CELL CYCLE
3jqj:J (LEU53) to (GLN139) CRYSTAL STRUCTURE OF THE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN C (TTHA1789) FROM THERMUS THEROMOPHILUS HB8 | MOAC, MOLYBDENUM COFACTOR (MOCO), MOCO BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, BIOSYNTHETIC PROTEIN, MOLYBDENUM COFACTOR BIOSYNTHESIS
3jqm:C (LEU53) to (GLN139) BINDING OF 5'-GTP TO MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOAC FROM THERMUS THEROMOPHILUS HB8 | MOAC, MOLYBDENUM COFACTOR (MOCO), MOCO BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, BIOSYNTHETIC PROTEIN, MOLYBDENUM COFACTOR BIOSYNTHESIS
2ym9:A (THR227) to (ASP283) SIPD FROM SALMONELLA TYPHIMURIUM | CELL INVASION, TYPE 3 SECRETION, T3SS, NEEDLE TIP PROTEIN, HOST PATHOGEN INTERACTION, BACTERIAL PATHOGENESIS, TIP COMPLEX
2yoj:A (SER288) to (TYR358) HCV NS5B POLYMERASE COMPLEXED WITH PYRIDONYLINDOLE COMPOUND | TRANSFERASE, INHIBITOR
2yoj:B (SER288) to (TYR358) HCV NS5B POLYMERASE COMPLEXED WITH PYRIDONYLINDOLE COMPOUND | TRANSFERASE, INHIBITOR
3jz0:A (LEU2) to (TYR71) LINB COMPLEXED WITH CLINDAMYCIN AND AMPCPP | ALPHA-BETA STRUCTURE, TRANSFERASE, TRANSFERASE-ANTIBIOTIC COMPLEX
3jz0:B (GLN4) to (LYS72) LINB COMPLEXED WITH CLINDAMYCIN AND AMPCPP | ALPHA-BETA STRUCTURE, TRANSFERASE, TRANSFERASE-ANTIBIOTIC COMPLEX
3jyy:A (GLN4) to (TYR71) SEMET LINB COMPLEXED WITH PPI | ALPHA-BETA STRUCTURE, TRANSFERASE
3jyy:B (GLN4) to (LYS72) SEMET LINB COMPLEXED WITH PPI | ALPHA-BETA STRUCTURE, TRANSFERASE
3k07:A (VAL65) to (ASP132) CRYSTAL STRUCTURE OF CUSA | TRANSMEMBRANE HELIX, CELL INNER MEMBRANE, CELL MEMBRANE, COPPER TRANSPORT, ION TRANSPORT, MEMBRANE, TRANSMEMBRANE, TRANSPORT, TRANSPORT PROTEIN
4obc:A (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV POLYMERASE NS5B GENOTYPE 2A JFH-1 ISOLATE WITH THE S15G, C223H, V321I RESISTANCE MUTATIONS AGAINST THE GUANOSINE ANALOG GS-0938 (PSI-3529238) | HEPATITIS, HCV, VIRAL POLYMERASE, RNA-DEPENDENT-RNA-POLYMERASE, RDRP, RESISTANCE, NUCLEOTIDE ANALOG INHIBITOR, VIRAL PROTEIN, TRANSFERASE
2yyb:B (PHE110) to (GLY158) CRYSTAL STRUCTURE OF TTHA1606 FROM THERMUS THERMOPHILUS HB8 | THERMUS THERMOPHILUS, STRUCTURAL GENOMICS, UNKNOWN FUNCTION, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
1lgr:A (GLN189) to (PHE255) INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM | LIGASE(AMIDE SYNTHETASE)
1lgr:B (GLN189) to (PHE255) INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM | LIGASE(AMIDE SYNTHETASE)
1lgr:C (GLN189) to (PHE255) INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM | LIGASE(AMIDE SYNTHETASE)
1lgr:D (GLN189) to (PHE255) INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM | LIGASE(AMIDE SYNTHETASE)
1lgr:E (GLN189) to (PHE255) INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM | LIGASE(AMIDE SYNTHETASE)
1lgr:F (GLN189) to (PHE255) INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM | LIGASE(AMIDE SYNTHETASE)
1lgr:G (GLN189) to (PHE255) INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM | LIGASE(AMIDE SYNTHETASE)
1lgr:H (GLN189) to (PHE255) INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM | LIGASE(AMIDE SYNTHETASE)
1lgr:I (GLN189) to (PHE255) INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM | LIGASE(AMIDE SYNTHETASE)
1lgr:J (GLN189) to (PHE255) INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM | LIGASE(AMIDE SYNTHETASE)
1lgr:K (GLN189) to (PHE255) INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM | LIGASE(AMIDE SYNTHETASE)
1lgr:L (GLN189) to (PHE255) INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM | LIGASE(AMIDE SYNTHETASE)
1lk5:B (TRP145) to (GLY207) STRUCTURE OF THE D-RIBOSE-5-PHOSPHATE ISOMERASE FROM PYROCOCCUS HORIKOSHII | ALPHA/BETA STRUCTURE, ISOMERASE
3k3j:A (SER61) to (GLU160) P38ALPHA BOUND TO NOVEL DFG-OUT COMPOUND PF-00416121 | P38ALPHA KINASE, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
2z4p:A (ARG16) to (ALA74) CRYSTAL STRUCTURE OF FFRP-DM1 | FFRP, FEAST/FAMINE REGULATORY PROTEIN, TRANSCRIPTIONAL REGULATOR, DNA BINDING PROTEIN
4oi6:B (THR15) to (GLU77) CRYSTAL STRUCTURE ANALYSIS OF NICKEL-BOUND FORM SCO4226 FROM STREPTOMYCES COELICOLOR A3(2) | NICKEL RESPONSIVE PROTEIN, STRUCTURAL GENOMICS, FERREDOXIN-LIKE FOLD, A NICKEL RESPONSIVE PROTEIN, NICKEL BINDING, METAL BINDING PROTEIN
3k58:A (ASP512) to (TYR594) CRYSTAL STRUCTURE OF E.COLI POL II-NORMAL DNA-DTTP TERNARY COMPLEX | PROTEIN-DNA COMPLEX, DNA DAMAGE, DNA REPAIR, DNA-BINDING, DNA- DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, SOS RESPONSE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3k59:A (PRO513) to (TYR594) CRYSTAL STRUCTURE OF E.COLI POL II-NORMAL DNA-DCTP TERNARY COMPLEX | PROTEIN-DNA COMPLEX, DNA DAMAGE, DNA REPAIR, DNA-BINDING, DNA- DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, SOS RESPONSE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3k5l:A (PRO513) to (TYR594) CRYSTAL STRUCTURE OF E.COLI POL II-ABASIC DNA-DATP LT(0, 3) TERNARY COMPLEX | DNA DAMAGE, DNA REPAIR, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, SOS RESPONSE, TRANSFERASE
3k5m:A (ASP512) to (TYR594) CRYSTAL STRUCTURE OF E.COLI POL II-ABASIC DNA-DDGTP LT(-2, 2) TERNARY COMPLEX | DNA DAMAGE, DNA REPAIR, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, SOS RESPONSE, TRANSFERASE
3k5n:A (PRO513) to (CYS599) CRYSTAL STRUCTURE OF E.COLI POL II-ABASIC DNA BINARY COMPLEX | DNA DAMAGE, DNA REPAIR, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, SOS RESPONSE, TRANSFERASE
4a48:A (SER16) to (VAL69) CROSSTALK BETWEEN CU(I) AND ZN(II) HOMEOSTASIS | TRANSPORT PROTEIN, COPPER HOMEOSTASIS, ZINC HOMEOSTASIS, ATX1, METAL-TRANSPORTING ATPASES
2o5d:A (THR287) to (TYR358) THIAZOLONE-ACYLSULFONAMIDES AS NOVEL HCV NS5B POLYMERASE ALLOSTERIC INHIBITORS: CONVERGENCE OF STRUCTURE-BASED DRUG DESIGN AND X-RAY CRYSTALLOGRAPHIC STUDY | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, STRUCTURE- BASED DRUG DESIGN, VIRAL PROTEIN
2o5d:B (THR286) to (TYR358) THIAZOLONE-ACYLSULFONAMIDES AS NOVEL HCV NS5B POLYMERASE ALLOSTERIC INHIBITORS: CONVERGENCE OF STRUCTURE-BASED DRUG DESIGN AND X-RAY CRYSTALLOGRAPHIC STUDY | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, STRUCTURE- BASED DRUG DESIGN, VIRAL PROTEIN
5cr0:A (ARG389) to (GLU466) HUMAN DNA POLYMERASE LAMBDA L431A MUTANT- MGDCTP BINARY AND COMPLEX WITH 6 PAIRED DNA | DNA POLYMERASE LAMBDA, TRANSFERASE-DNA COMPLEX
2zb0:A (SER61) to (GLU160) CRYSTAL STRUCTURE OF P38 IN COMPLEX WITH BIPHENYL AMIDE INHIBITOR | SERINE/THREONINE PROTEIN KINASE, MAP KINASE, P38, ATP-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHORYLATION, TRANSFERASE
3k7r:A (SER16) to (GLN72) CRYSTAL STRUCTURE OF [TM][CUATX1]3 | FERREDOXIN-LIKE FOLD, PROTEIN-METAL-DRUG COMPLEX, CU-MO METAL CLUSTER, CHAPERONE, COPPER TRANSPORT, ION TRANSPORT, METAL-BINDING, TRANSPORT
3k7r:C (SER16) to (GLN72) CRYSTAL STRUCTURE OF [TM][CUATX1]3 | FERREDOXIN-LIKE FOLD, PROTEIN-METAL-DRUG COMPLEX, CU-MO METAL CLUSTER, CHAPERONE, COPPER TRANSPORT, ION TRANSPORT, METAL-BINDING, TRANSPORT
3k7r:F (SER16) to (LEU73) CRYSTAL STRUCTURE OF [TM][CUATX1]3 | FERREDOXIN-LIKE FOLD, PROTEIN-METAL-DRUG COMPLEX, CU-MO METAL CLUSTER, CHAPERONE, COPPER TRANSPORT, ION TRANSPORT, METAL-BINDING, TRANSPORT
3k7r:G (CYS15) to (LEU73) CRYSTAL STRUCTURE OF [TM][CUATX1]3 | FERREDOXIN-LIKE FOLD, PROTEIN-METAL-DRUG COMPLEX, CU-MO METAL CLUSTER, CHAPERONE, COPPER TRANSPORT, ION TRANSPORT, METAL-BINDING, TRANSPORT
3k7r:I (SER16) to (LEU73) CRYSTAL STRUCTURE OF [TM][CUATX1]3 | FERREDOXIN-LIKE FOLD, PROTEIN-METAL-DRUG COMPLEX, CU-MO METAL CLUSTER, CHAPERONE, COPPER TRANSPORT, ION TRANSPORT, METAL-BINDING, TRANSPORT
4olc:A (THR138) to (THR193) CARBAMATE KINASE FROM GIARDIA LAMBLIA THIOCARBAMOYLATED BY DISULFIRAM ON CYS242 | ADP, MG2+, CARBAMATE, CARBAMOYL PHOSPHATE, TRANSFERASE
4olc:B (GLU139) to (CYS192) CARBAMATE KINASE FROM GIARDIA LAMBLIA THIOCARBAMOYLATED BY DISULFIRAM ON CYS242 | ADP, MG2+, CARBAMATE, CARBAMOYL PHOSPHATE, TRANSFERASE
4olc:C (THR138) to (CYS192) CARBAMATE KINASE FROM GIARDIA LAMBLIA THIOCARBAMOYLATED BY DISULFIRAM ON CYS242 | ADP, MG2+, CARBAMATE, CARBAMOYL PHOSPHATE, TRANSFERASE
4olc:D (THR138) to (THR193) CARBAMATE KINASE FROM GIARDIA LAMBLIA THIOCARBAMOYLATED BY DISULFIRAM ON CYS242 | ADP, MG2+, CARBAMATE, CARBAMOYL PHOSPHATE, TRANSFERASE
1m55:A (GLN50) to (VAL136) CATALYTIC DOMAIN OF THE ADENO ASSOCIATED VIRUS TYPE 5 REP PROTEIN | ENDONUCLEASE, REP, ROLLING CIRCLE REPLICATION, ADENO- ASSOCIATED VIRUS, VIRAL PROTEIN
1m55:B (GLN50) to (VAL136) CATALYTIC DOMAIN OF THE ADENO ASSOCIATED VIRUS TYPE 5 REP PROTEIN | ENDONUCLEASE, REP, ROLLING CIRCLE REPLICATION, ADENO- ASSOCIATED VIRUS, VIRAL PROTEIN
4a9y:A (SER61) to (GLU160) P38ALPHA MAP KINASE BOUND TO CMPD 8 | TRANSFERASE
4aa0:A (SER61) to (GLU160) P38ALPHA MAP KINASE BOUND TO CMPD 2 | SERINE/THREONINE KINASE, TRANSFERASE
2zku:A (THR286) to (TYR358) STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM | HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE
2zku:B (THR287) to (TYR358) STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM | HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE
2zku:C (THR286) to (TYR358) STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM | HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE
2zku:D (THR286) to (TYR358) STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM | HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE
3ke6:A (HIS432) to (GLY513) THE CRYSTAL STRUCTURE OF THE RSBU AND RSBW DOMAINS OF RV1364C FROM MYCOBACTERIUM TUBERCULOSIS | ANTI-SIGMA FACTOR, ANTI-SIGMA FACTOR ANTAGONIST, PHOSPHATASE, PP2C, SERINE KINASE, ATPASE, UNKNOWN FUNCTION
3ke6:B (ASP431) to (HIS512) THE CRYSTAL STRUCTURE OF THE RSBU AND RSBW DOMAINS OF RV1364C FROM MYCOBACTERIUM TUBERCULOSIS | ANTI-SIGMA FACTOR, ANTI-SIGMA FACTOR ANTAGONIST, PHOSPHATASE, PP2C, SERINE KINASE, ATPASE, UNKNOWN FUNCTION
2znz:H (SER101) to (ILE157) CRYSTAL STRUCTURE OF FFRP | TRANSCRIPTION, DNA-BINDING, TRANSCRIPTION REGULATION, DNA BINDING PROTEIN
3khg:A (GLU79) to (SER145) DPO4 EXTENSION TERNARY COMPLEX WITH MISINSERTED A OPPOSITE THE 2- AMINOFLUORENE-GUANINE [AF]G LESION | LESION BYPASS, DNA POLYMERASE, Y-FAMILY POLYMERASE, 2-AMINOFLUORENE, SEMI-TARGETED MUTAGENESIS, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE- DNA COMPLEX
3khg:B (ARG1077) to (SER1145) DPO4 EXTENSION TERNARY COMPLEX WITH MISINSERTED A OPPOSITE THE 2- AMINOFLUORENE-GUANINE [AF]G LESION | LESION BYPASS, DNA POLYMERASE, Y-FAMILY POLYMERASE, 2-AMINOFLUORENE, SEMI-TARGETED MUTAGENESIS, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE- DNA COMPLEX
5czb:A (THR287) to (TYR358) HCV NS5B IN COMPLEX WITH LIGAND IDX17119-5 | HCV POLYMERASE, IDENIX, INHIBITOR, PROTEROS BIOSTRUCTURES GMBH, REPLICATION
5czb:B (THR287) to (TYR358) HCV NS5B IN COMPLEX WITH LIGAND IDX17119-5 | HCV POLYMERASE, IDENIX, INHIBITOR, PROTEROS BIOSTRUCTURES GMBH, REPLICATION
4ox8:A (LEU18) to (ARG84) STRUCTURE OF PROCHLOROCOCCUS MARINUS STR. MIT 9313 CSOS1 | STRUCTURAL PROTEIN, BACTERIAL MICROCOMPARTMENT
1y1v:B (PRO551) to (ARG617) REFINED RNA POLYMERASE II-TFIIS COMPLEX | RNA POLYMERASE II, TFIIS, TRANSCRIPTION, ELONGATION, TRANSFERASE/TRANSCRIPTION COMPLEX
4oya:A (ARG66) to (GLY150) HUMAN SOLAC COMPLEXED WITH (4-AMINOFURAZAN-3-YL)-[3-(1H-BENZOIMIDAZOL- 2-YLMETHOXY)PHENYL]METHANONE | LYASE
4oyb:A (ARG66) to (GLY150) CRYSTAL STRUCTURE ANALYSIS OF THE SOLAC | LYASE
4oym:A (ARG66) to (GLY150) HUMAN SOLAC COMPLEXED WITH (4-AMINO-FURAZAN-3-YL)-(3-METHOXY-PHENYL)- METHANONE | LYASE
4oyp:A (ARG66) to (GLY150) HUMAN SOLAC COMPLEXED WITH 1-BENZOFURAN-2-CARBOXYLIC ACID | LYASE
3kle:A (TRP153) to (ASP218) CRYSTAL STRUCTURE OF AZT-RESISTANT HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO A DSDNA WITH A BOUND EXCISION PRODUCT, AZTPPPPA | AZT RESISTANCE MECHANISM, HIV-1, REVERSE TRANSCRIPTASE, RT, AZT, RESISTANCE MUTATIONS, P51/P66, NUCLEOSIDE INHIBITOR, NUCLEOTIDE EXCISION, THYMIDINE ANALOG MUTATIONS, AIDS, HIV, DNA POLYMERASE, NRTI, NRTI RESISTANCE, AZTPPPPA, AZTP4A, AZT ADENOSINE DINUCLEOSIDE TETRAPHOSPHATE, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
4adp:A (THR287) to (TYR358) HCV-J6 NS5B POLYMERASE V405I MUTANT | HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, TRANSFERASE, RNA-DIRECTED RNA POLYMERASE, RDRP, DE NOVO INITIATION, PRIMING
4aex:A (SER288) to (TYR358) HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 2.4 ANGSTROM IN A PRIMITIVE ORTHORHOMBIC SPACE GROUP | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
4aex:B (SER288) to (TYR358) HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 2.4 ANGSTROM IN A PRIMITIVE ORTHORHOMBIC SPACE GROUP | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
5d4b:A (ARG305) to (GLU382) STRUCTURAL BASIS FOR A NEW TEMPLATED ACTIVITY BY TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE: IMPLICATIONS FOR V(D)J RECOMBINATION | TDT, SYNAPSIS, DOUBLE STRAND BREAKS, TRANSFERASE
5d4b:B (ARG305) to (GLU386) STRUCTURAL BASIS FOR A NEW TEMPLATED ACTIVITY BY TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE: IMPLICATIONS FOR V(D)J RECOMBINATION | TDT, SYNAPSIS, DOUBLE STRAND BREAKS, TRANSFERASE
4ahc:A (LYS508) to (LYS585) CRYSTAL STRUCTURE OF AN EVOLVED REPLICATING DNA POLYMERASE | TRANSFERASE, B FAMILY POLYMERASE, APOENZYME
4ahc:B (LYS508) to (LYS585) CRYSTAL STRUCTURE OF AN EVOLVED REPLICATING DNA POLYMERASE | TRANSFERASE, B FAMILY POLYMERASE, APOENZYME
4p52:A (GLY241) to (SER299) CRYSTAL STRUCTURE OF HOMOSERINE KINASE FROM CYTOPHAGA HUTCHINSONII ATCC 33406, NYSGRC TARGET 032717. | STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NYSGRC, PSI- BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM
1y7p:B (GLY14) to (GLU76) 1.9 A CRYSTAL STRUCTURE OF A PROTEIN OF UNKNOWN FUNCTION AF1403 FROM ARCHAEOGLOBUS FULGIDUS, PROBABLE METABOLIC REGULATOR | STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, ARCHAEOGLOBUS FULGIDUS, ALPHA-BETA-ALPHA SANDWICH, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
4p75:D (PRO93) to (PRO166) PHERS IN COMPLEX WITH COMPOUND 4A | PHENYLALANINE TRNA SYNTHETASE, PHERS, LIGASE-LIGASE INHIBITOR COMPLEX
4p7v:A (LEU14) to (PRO78) STRUCTURAL INSIGHTS INTO HIGHER-ORDER ASSEMBLY AND FUNCTION OF THE BACTERIAL MICROCOMPARTMENT PROTEIN PDUA | BACTERIAL MICROCOMPARTMENT SHELL PROTEIN, STRUCTURAL PROTEIN, ELECTRON TRANSPORT
5d7v:B (GLN229) to (GLU322) CRYSTAL STRUCTURE OF PTK6 KINASE DOMAIN | TRANSFERASE, KINASE, BRK, APO
1yft:A (SER3) to (TYR130) THE CRYSTAL STRUCTURE OF THE CATALYTIC FRAGMENT OF ALANYL- TRNA SYNTHETASE IN COMPLEX WTIH GLYCINE | ALPHA-BETA FOLD, AMINO ACID BINDING, HELIX-LOOP HELIX MOTIF, LIGASE
1mwq:A (ARG21) to (PRO93) STRUCTURE OF HI0828, A HYPOTHETICAL PROTEIN FROM HAEMOPHILUS INFLUENZAE WITH A PUTATIVE ACTIVE-SITE PHOSPHOHISTIDINE | HI0828, YCII_HAEIN, HYPOTHETICAL PROTEIN, STRUCTURAL GENOMICS, STRUCTURE 2 FUNCTION PROJECT, S2F, UNKNOWN FUNCTION
3kta:D (LYS1009) to (ASP1097) STRUCTURAL BASIS FOR ADENYLATE KINASE ACTIVITY IN ABC ATPASES | STRUCTURAL MAINTENANCE OF CHROMOSOMES, SMC, ABC ATPASE, CFTR, ADENYLATE KINASE, AP5A, TRANSFERASE
3kxc:A (ASP70) to (PHE150) MUTANT TRANSPORT PROTEIN | HETERODIMER, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, GOLGI APPARATUS, LIPOPROTEIN, PALMITATE, TRANSPORT, TRANSPORT PROTEIN
3kxc:C (ASP60) to (VAL143) MUTANT TRANSPORT PROTEIN | HETERODIMER, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, GOLGI APPARATUS, LIPOPROTEIN, PALMITATE, TRANSPORT, TRANSPORT PROTEIN
3ab4:O (GLU278) to (ASP342) CRYSTAL STRUCTURE OF FEEDBACK INHIBITION RESISTANT MUTANT OF ASPARTATE KINASE FROM CORYNEBACTERIUM GLUTAMICUM IN COMPLEX WITH LYSINE AND THREONINE | ASPARTATE KINASE, CONCERTED INHIBITION, ALTERNATIVE INITIATION, AMINO-ACID BIOSYNTHESIS, ATP-BINDING, DIAMINOPIMELATE BIOSYNTHESIS, KINASE, LYSINE BIOSYNTHESIS, NUCLEOTIDE-BINDING, TRANSFERASE
5dcx:A (GLN50) to (THR137) STRUCTURAL STUDIES OF AAV2 REP68 REVEAL A PARTIALLY STRUCTURED LINKER AND COMPACT DOMAIN CONFORMATION | PARVOVIRUS, ADENO-ASSOCIATED VIRUS, DNA REPLICATION, SMALL-ANGLE X- RAY SCATTERING, DNA BINDING PROTEIN, REP PROTEINS
5dcx:B (GLN50) to (THR137) STRUCTURAL STUDIES OF AAV2 REP68 REVEAL A PARTIALLY STRUCTURED LINKER AND COMPACT DOMAIN CONFORMATION | PARVOVIRUS, ADENO-ASSOCIATED VIRUS, DNA REPLICATION, SMALL-ANGLE X- RAY SCATTERING, DNA BINDING PROTEIN, REP PROTEINS
5dcx:D (GLN50) to (THR137) STRUCTURAL STUDIES OF AAV2 REP68 REVEAL A PARTIALLY STRUCTURED LINKER AND COMPACT DOMAIN CONFORMATION | PARVOVIRUS, ADENO-ASSOCIATED VIRUS, DNA REPLICATION, SMALL-ANGLE X- RAY SCATTERING, DNA BINDING PROTEIN, REP PROTEINS
5dcx:F (GLN50) to (THR137) STRUCTURAL STUDIES OF AAV2 REP68 REVEAL A PARTIALLY STRUCTURED LINKER AND COMPACT DOMAIN CONFORMATION | PARVOVIRUS, ADENO-ASSOCIATED VIRUS, DNA REPLICATION, SMALL-ANGLE X- RAY SCATTERING, DNA BINDING PROTEIN, REP PROTEINS
5dcx:H (GLN50) to (THR137) STRUCTURAL STUDIES OF AAV2 REP68 REVEAL A PARTIALLY STRUCTURED LINKER AND COMPACT DOMAIN CONFORMATION | PARVOVIRUS, ADENO-ASSOCIATED VIRUS, DNA REPLICATION, SMALL-ANGLE X- RAY SCATTERING, DNA BINDING PROTEIN, REP PROTEINS
5dcx:I (GLN50) to (THR137) STRUCTURAL STUDIES OF AAV2 REP68 REVEAL A PARTIALLY STRUCTURED LINKER AND COMPACT DOMAIN CONFORMATION | PARVOVIRUS, ADENO-ASSOCIATED VIRUS, DNA REPLICATION, SMALL-ANGLE X- RAY SCATTERING, DNA BINDING PROTEIN, REP PROTEINS
5dcx:J (GLU49) to (THR137) STRUCTURAL STUDIES OF AAV2 REP68 REVEAL A PARTIALLY STRUCTURED LINKER AND COMPACT DOMAIN CONFORMATION | PARVOVIRUS, ADENO-ASSOCIATED VIRUS, DNA REPLICATION, SMALL-ANGLE X- RAY SCATTERING, DNA BINDING PROTEIN, REP PROTEINS
5dcx:K (GLN50) to (THR137) STRUCTURAL STUDIES OF AAV2 REP68 REVEAL A PARTIALLY STRUCTURED LINKER AND COMPACT DOMAIN CONFORMATION | PARVOVIRUS, ADENO-ASSOCIATED VIRUS, DNA REPLICATION, SMALL-ANGLE X- RAY SCATTERING, DNA BINDING PROTEIN, REP PROTEINS
5ddy:A (ARG389) to (VAL462) BINARY COMPLEX OF HUMAN POLYMERASE LAMBDA WITH DCTP | POLYMERASE LAMBDA, TRANSFERASE
5ddy:E (ARG389) to (VAL462) BINARY COMPLEX OF HUMAN POLYMERASE LAMBDA WITH DCTP | POLYMERASE LAMBDA, TRANSFERASE
3l12:B (THR92) to (LEU149) CRYSTAL STRUCTURE OF PUTATIVE GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE (YP_165505.1) FROM SILICIBACTER POMEROYI DSS-3 AT 1.60 A RESOLUTION | PUTATIVE GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, HYDROLASE
1yuy:A (THR287) to (TYR358) HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2A | NS5B POLYMERASE GENOTYPE 2A, VIRAL PROTEIN
1yv2:A (THR287) to (LEU374) HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2A | NS5B POLYMERASE GENOTYPE 2A, TRANSFERASE
1yvf:A (THR287) to (TYR358) HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH INHIBITOR PHA-00729145 | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE
1yvz:A (THR286) to (TYR358) HEPATITIS C VIRUS RNA POLYMERASE GENOTYPE 2A IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | NS5B POLYMERASE GENOTYPE 2A, NON-NUCLEOSIDE INHIBITOR, VIRAL PROTEIN
1yw2:A (SER1061) to (GLU1160) MUTATED MUS MUSCULUS P38 KINASE (MP38) | TRANSFERASE
5dku:A (PHE539) to (ILE620) C-TERMINAL HIS TAGGED APPOL EXONUCLEASE MUTANT | DNA POLYMERASE, TRANSFERASE
4pl3:A (ARG611) to (PRO699) CRYSTAL STRUCTURE OF MURINE IRE1 IN COMPLEX WITH MKC9989 INHIBITOR | SCHIFF BASE, HYDROXY ARYL ALDEHYDES (HAA), INHIBITOR COMPLEX, UNFOLDED PROTEIN RESPONSE, ENDORIBONUCLEASE, TRANSFERASE, HYDROLASE- INHIBITOR COMPLEX
4pl4:B (ARG611) to (PRO699) CRYSTAL STRUCTURE OF MURINE IRE1 IN COMPLEX WITH OICR464 INHIBITOR | SCHIFF BASE, HYDROXY ARYL ALDEHYDES (HAA), INHIBITOR COMPLEX, UNFOLDED PROTEIN RESPONSE, ENDORIBONUCLEASE
4pl5:A (ARG611) to (PRO699) CRYSTAL STRUCTURE OF MURINE IRE1 IN COMPLEX WITH OICR573 INHIBITOR | SCHIFF BASE, HYDROXY ARYL ALDEHYDES (HAA), INHIBITOR COMPLEX, UNFOLDED PROTEIN RESPONSE, ENDORIBONUCLEASE
4pl5:C (ARG611) to (PRO699) CRYSTAL STRUCTURE OF MURINE IRE1 IN COMPLEX WITH OICR573 INHIBITOR | SCHIFF BASE, HYDROXY ARYL ALDEHYDES (HAA), INHIBITOR COMPLEX, UNFOLDED PROTEIN RESPONSE, ENDORIBONUCLEASE
3l76:A (ILE371) to (PRO422) CRYSTAL STRUCTURE OF ASPARTATE KINASE FROM SYNECHOCYSTIS | ASPARTOKINASE, SYNECHOCYSTIS, ALLOSTERY, ACT DOMAINS, KINASE, TRANSFERASE
3l76:B (ILE371) to (PRO422) CRYSTAL STRUCTURE OF ASPARTATE KINASE FROM SYNECHOCYSTIS | ASPARTOKINASE, SYNECHOCYSTIS, ALLOSTERY, ACT DOMAINS, KINASE, TRANSFERASE
5dm3:C (THR179) to (PHE248) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM CHROMOHALOBACTER SALEXIGENS DSM 3043(CSAL_0679, TARGET EFI-550015) WITH BOUND ADP | ENZYME FUNCTION INITIATIVE, EFI, STRUCTURAL GENOMICS, LIGASE
3l8b:A (ASP579) to (ARG685) CRYSTAL STRUCTURE OF A REPLICATIVE DNA POLYMERASE BOUND TO THE OXIDIZED GUANINE LESION GUANIDINOHYDANTOIN | DNA POLYMERASE RB69 GP43, PROTEIN-DNA COMPLEX, OXIDATIVE DNA LESION, GUANIDINOHYDANTOIN, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, EXONUCLEASE, HYDROLASE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE- DNA COMPLEX
1z4u:A (THR287) to (TYR358) HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH INHIBITOR PHA-00799585 | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE
4prv:A (GLU183) to (THR245) E. COLI GYRB 43-KDA N-TERMINAL FRAGMENT IN COMPLEX WITH ADP | GYRB, ATP HYDROLYSIS, ISOMERASE
4prx:A (GLU183) to (THR245) E. COLI GYRB 43-KDA N-TERMINAL FRAGMENT IN COMPLEX WITH ADP+PI | GYRB, ATP HYDROLYSIS, ISOMERASE
3lfa:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH DASATINIB | THIAZOLE-UREA, DFG-OUT, SAR, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3lfe:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH RL116 | THIAZOLE-UREA, DFG-OUT, SAR, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3lfd:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH RL113 | THIAZOLE-UREA, DFG-OUT, SAR, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
4pu9:A (GLU185) to (THR245) E. COLI GYRB 43-KDA N-TERMINAL FRAGMENT IN COMPLEX WITH ADP-BEF3 | GYRB, ATP HYDROLYSIS, ISOMERASE
4pww:A (ILE20) to (THR75) CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR494. | STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, DE NOVO, OR494, DE NOVO PROTEIN
1ze1:C (THR95) to (ALA188) CONFORMATIONAL CHANGE OF PSEUDOURIDINE 55 SYNTHASE UPON ITS ASSOCIATION WITH RNA SUBSTRATE | RNA MODIFICATION ENZYME, LYASE
3lkh:A (SER288) to (TYR358) INHIBITORS OF HEPATITIS C VIRUS POLYMERASE: SYNTHESIS AND CHARACTERIZATION OF NOVEL 6-FLUORO-N-[2-HYDROXY-1(S)-BENZAMIDES | HCV, NS5B, POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST CELL MEMBRANE, HOST CYTOPLASM, HOST ENDOPLASMIC RETICULUM, HOST LIPID DROPLET, HOST MEMBRANE, HOST MITOCHONDRION, HOST NUCLEUS, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3lkh:B (SER288) to (TYR358) INHIBITORS OF HEPATITIS C VIRUS POLYMERASE: SYNTHESIS AND CHARACTERIZATION OF NOVEL 6-FLUORO-N-[2-HYDROXY-1(S)-BENZAMIDES | HCV, NS5B, POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST CELL MEMBRANE, HOST CYTOPLASM, HOST ENDOPLASMIC RETICULUM, HOST LIPID DROPLET, HOST MEMBRANE, HOST MITOCHONDRION, HOST NUCLEUS, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
4at8:A (ASN67) to (THR159) CRYSTAL STRUCTURE OF THE NF90-NF45 DIMERISATION DOMAIN COMPLEX WITH ATP | TRANSCRIPTION, DRPB76, NFAR, ILF3, ILF2, TEMPLATE-FREE NUCLEOTIDYLTRANSFERASE FOLD
4at8:C (ASN67) to (THR159) CRYSTAL STRUCTURE OF THE NF90-NF45 DIMERISATION DOMAIN COMPLEX WITH ATP | TRANSCRIPTION, DRPB76, NFAR, ILF3, ILF2, TEMPLATE-FREE NUCLEOTIDYLTRANSFERASE FOLD
4atb:A (ASN67) to (THR159) CRYSTAL STRUCTURE OF THE NF90-NF45 DIMERISATION DOMAIN COMPLEX WITH CTP | IMMUNE SYSTEM, TEMPLATE-FREE NUCLEOTIDYL TRANSFERASE FOLD
4atb:C (ASN67) to (THR159) CRYSTAL STRUCTURE OF THE NF90-NF45 DIMERISATION DOMAIN COMPLEX WITH CTP | IMMUNE SYSTEM, TEMPLATE-FREE NUCLEOTIDYL TRANSFERASE FOLD
4q43:A (ASP77) to (PRO144) POLYMERASE-DAMAGED DNA COMPLEX | POLYMERASE, DNA POLYMERASE, TRANSLESION SYNTHESIS, TRANSFERASE-DNA COMPLEX
4q43:F (ASP77) to (ALA143) POLYMERASE-DAMAGED DNA COMPLEX | POLYMERASE, DNA POLYMERASE, TRANSLESION SYNTHESIS, TRANSFERASE-DNA COMPLEX
4q44:A (PHE76) to (PRO144) POLYMERASE-DAMAGED DNA COMPLEX | POLYMERASE, DNA POLYMERASE, DNA, TRANSFERASE-DNA COMPLEX
4q44:F (ASP77) to (ALA143) POLYMERASE-DAMAGED DNA COMPLEX | POLYMERASE, DNA POLYMERASE, DNA, TRANSFERASE-DNA COMPLEX
4q45:F (ASP77) to (PRO144) DNA POLYMERASE- DAMAGED DNA COMPLEX | POLYMERASE, DNA POLYMERASE, DNA, TRANSFERASE-DNA COMPLEX
4q45:A (ASP77) to (ALA143) DNA POLYMERASE- DAMAGED DNA COMPLEX | POLYMERASE, DNA POLYMERASE, DNA, TRANSFERASE-DNA COMPLEX
1zpv:C (ILE15) to (SER78) ACT DOMAIN PROTEIN FROM STREPTOCOCCUS PNEUMONIAE | ACT DOMAIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
4au6:A (GLN595) to (SER671) LOCATION OF THE DSRNA-DEPENDENT POLYMERASE, VP1, IN ROTAVIRUS PARTICLES | VIRAL PROTEIN, DSRNA-DEPENDENT
4au6:B (GLN595) to (SER671) LOCATION OF THE DSRNA-DEPENDENT POLYMERASE, VP1, IN ROTAVIRUS PARTICLES | VIRAL PROTEIN, DSRNA-DEPENDENT
4au6:C (GLN595) to (SER671) LOCATION OF THE DSRNA-DEPENDENT POLYMERASE, VP1, IN ROTAVIRUS PARTICLES | VIRAL PROTEIN, DSRNA-DEPENDENT
4au6:D (GLN595) to (SER671) LOCATION OF THE DSRNA-DEPENDENT POLYMERASE, VP1, IN ROTAVIRUS PARTICLES | VIRAL PROTEIN, DSRNA-DEPENDENT
4au6:E (GLN595) to (SER671) LOCATION OF THE DSRNA-DEPENDENT POLYMERASE, VP1, IN ROTAVIRUS PARTICLES | VIRAL PROTEIN, DSRNA-DEPENDENT
3lsq:B (ASN232) to (THR279) TRYPANOSOMA BRUCEI SERYL-TRNA SYNTHETASE | AMINOACYL-TRNA SYNTHETASE, TRNA LIGASE, AARS, SERRS, TRANSLATION, ATP-BINDING, NUCLEOTIDE-BINDING, STRUCTURAL GENOMICS, MEDICAL STRUCTURAL GENOMICS OF PATHOGENIC PROTOZOA, MSGPP, LIGASE
3lss:B (ASN232) to (THR279) TRYPANOSOMA BRUCEI SERYL-TRNA SYNTHETASE IN COMPLEX WITH ATP | AMINOACYL-TRNA SYNTHETASE, TRNA LIGASE, AARS, SERRS, TRANSLATION, ATP-BINDING, NUCLEOTIDE-BINDING, STRUCTURAL GENOMICS, MEDICAL STRUCTURAL GENOMICS OF PATHOGENIC PROTOZOA, MSGPP, LIGASE
1zvp:B (LEU32) to (HIS78) CRYSTAL STRUCTURE OF A PROTEIN OF UNKNOWN FUNCTION VC0802 FROM VIBRIO CHOLERAE, POSSIBLE TRANSPORT PROTEIN | VIBRIO CHOLERAE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
3lwl:A (PHE769) to (GLY824) STRUCTURE OF KLENOW FRAGMENT OF TAQ POLYMERASE IN COMPLEX WITH AN ABASIC SITE | DNA REPLICATION, DNA REPAIR, DNA POLYMERASES, ABASIC SITES, TRANSLESION SYNTHESIS, DNA DAMAGE, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, AMINO ACID-TEMPLATING MECHANISM, TRANSFERASE-DNA COMPLEX
3lwm:A (PHE769) to (GLY824) STRUCTURE OF THE LARGE FRAGMENT OF THERMUS AQUATICUS DNA POLYMERASE I IN COMPLEX WITH A BLUNT-ENDED DNA AND DDATP | DNA REPLICATION, DNA POLYMERASES, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, AMINO ACID-TEMPLATING MECHANISM, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX, BLUNT-ENDED DNA, TEMPLATE- INDEPENDENT DNA SYNTHESIS, TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE, TEMPLATE-INDEPENDENT NUCLEOTIDE ADDITION
3auo:A (PRO159) to (GLY228) DNA POLYMERASE X FROM THERMUS THERMOPHILUS HB8 TERNARY COMPLEX WITH 1- NT GAPPED DNA AND DDGTP | RSGI, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, POLXC DOMAIN, PHP DOMAIN, DNA POLYMERASE, DRP LYASE, AP ENDONUCLEASE, 3'-5' EXONUCLEASE, DNA REPAIR, DNA BINDING, NUCLEOTIDE BINDING, TRANSFERASE-DNA COMPLEX
3auo:B (PRO159) to (ALA226) DNA POLYMERASE X FROM THERMUS THERMOPHILUS HB8 TERNARY COMPLEX WITH 1- NT GAPPED DNA AND DDGTP | RSGI, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, POLXC DOMAIN, PHP DOMAIN, DNA POLYMERASE, DRP LYASE, AP ENDONUCLEASE, 3'-5' EXONUCLEASE, DNA REPAIR, DNA BINDING, NUCLEOTIDE BINDING, TRANSFERASE-DNA COMPLEX
2a0f:B (ILE25) to (ASN88) STRUCTURE OF D236A MUTANT E. COLI ASPARTATE TRANSCARBAMOYLASE IN PRESENCE OF PHOSPHONOACETAMIDE AT 2.90 A RESOLUTION | HOMOTROPIC COOPERATIVITY, CATALYTIC CYCLE, ALLOSTERIC REGULATION, ALTERNATE CONFORMATIONS, TRANSFERASE/TRANSFERASE REGULATOR COMPLEX
2a0f:D (GLN24) to (ILE86) STRUCTURE OF D236A MUTANT E. COLI ASPARTATE TRANSCARBAMOYLASE IN PRESENCE OF PHOSPHONOACETAMIDE AT 2.90 A RESOLUTION | HOMOTROPIC COOPERATIVITY, CATALYTIC CYCLE, ALLOSTERIC REGULATION, ALTERNATE CONFORMATIONS, TRANSFERASE/TRANSFERASE REGULATOR COMPLEX
2a2d:A (CYS379) to (LEU453) X-RAY STRUCTURE OF HUMAN N-ACETYL GALACTOSAMINE KINASE COMPLEXED WITH MN-AMPPNP AND N-ACETYL GLACTOSAMINE | KINASE, GALACTOKINASE, TRANSFERASE
4qcl:A (LYS970) to (ASP1039) CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF HUMAN DNA POLYMERASE ALPHA IN TERNARY COMPLEX WITH AN RNA-PRIMED DNA TEMPLATE AND DCTP | B-FAMILY DNA POLYMERASE, DNA REPLICATION, TRANSFERASE-DNA-RNA COMPLEX
4b3q:B (LEU168) to (HIS235) STRUCTURES OF HIV-1 RT AND RNA-DNA COMPLEX REVEAL A UNIQUE RT CONFORMATION AND SUBSTRATE INTERFACE | HYDROLASE-DNA-RNA COMPLEX, RNASE H, HYBRID
3ay0:B (GLU13) to (VAL61) CRYSTAL STRUCTURE OF METHANOCALDOCOCCUS JANNASCHII TRM5 IN COMPLEX WITH ADENOSINE | ROSSMANN FOLD, METHYLTRANSFERASE, ADOMET BINDING, TRANSFERASE
4b4z:B (ARG1) to (GLU76) CRYSTAL STRUCTURE OF A COMPLEX BETWEEN ACTINOMADURA R39 DD-PEPTIDASE AND A SULFONAMIDE BORONATE INHIBITOR | HYDROLASE, BORONIC ACID, PEPTIDOGLYCAN
5edw:A (LYS78) to (SER145) TERNARY STRUCTURE OF DPO4 BOUND TO G IN THE TEMPLATE BASE PAIRED WITH INCOMING DTTP | DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
2a6m:A (ALA35) to (THR115) CRYSTAL STRUCTURE OF THE ISHP608 TRANSPOSASE | RNA RECOGNITION MOTIF, TRANSCRIPTION/DNA COMPLEX
3m9o:B (GLU79) to (SER145) CRYSTAL STRUCTURE OF DPO4 IN COMPLEX WITH DNA CONTAINING THE MAJOR CISPLATIN LESION | DPO4, TRANSLESION DNA SYNTHESIS, TLS, CISPLATIN, Y-FAMILY DNA POLYMERASE, PROTEIN-DNA COMPLEX, DNA, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3m9m:B (LYS78) to (SER145) CRYSTAL STRUCTURE OF DPO4 IN COMPLEX WITH DNA CONTAINING THE MAJOR CISPLATIN LESION | DPO4, TRANSLESION DNA SYNTHESIS, TLS, CISPLATIN, Y-FAMILY DNA POLYMERASE, PROTEIN-DNA COMPLEX, DNA, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3m9n:B (GLU79) to (SER145) CRYSTAL STRUCTURE OF DPO4 IN COMPLEX WITH DNA CONTAINING THE MAJOR CISPLATIN LESION | DPO4, TRANSLESION DNA SYNTHESIS, TLS, CISPLATIN, Y-FAMILY DNA POLYMERASE, PROTEIN-DNA COMPLEX, DNA, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
5ehk:A (VAL840) to (LEU905) CRYSTAL STRUCTURE OF TRNA DEPENDENT LANTIBIOTIC DEHYDRATASE MIBB FROM MICROBISPORA SP. 107891 | LANTIBIOTIC DEHYDRATASE, NAI-107, MICROBISPORA SP. 107891, TRNA DEPENDENT, HYDROLASE
5ehk:B (PRO841) to (LEU905) CRYSTAL STRUCTURE OF TRNA DEPENDENT LANTIBIOTIC DEHYDRATASE MIBB FROM MICROBISPORA SP. 107891 | LANTIBIOTIC DEHYDRATASE, NAI-107, MICROBISPORA SP. 107891, TRNA DEPENDENT, HYDROLASE
3maq:A (PRO513) to (TYR594) CRYSTAL STRUCTURE OF E.COLI POL II-NORMAL DNA-DGTP TERNARY COMPLEX | PROTEIN-DNA COMPLEX, DNA DAMAGE, DNA REPAIR, DNA-BINDING, DNA- DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, SOS RESPONSE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3mcn:B (PHE14) to (ILE104) CRYSTAL STRUCTURE OF THE 6-HYROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE DIHYDROPTEROATE SYNTHASE BIFUNCTIONAL ENZYME FROM FRANCISELLA TULARENSIS | FOLATE, TIM BARREL, KINASE, SYNTHASE, HPPK, DHPS, PTERIN, TRANSFERASE
3mf5:A (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH AMIDE BIOISOSTERE THUMB SITE INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE
3mf5:B (THR286) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH AMIDE BIOISOSTERE THUMB SITE INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE
3mgm:A (GLY82) to (ARG142) CRYSTAL STRUCTURE OF HUMAN NUDT16 | HNUDT16, NUDIX FOLD, TWO DOMAINS, DIMMER, HYDROLASE
3mgm:B (GLY82) to (ARG142) CRYSTAL STRUCTURE OF HUMAN NUDT16 | HNUDT16, NUDIX FOLD, TWO DOMAINS, DIMMER, HYDROLASE
3bgo:P (CYS23) to (GLU70) AZIDE COMPLEX OF ENGINEERED SUBTILISIN SUBT_BACAM | AZIDE SWITCH, ANION SENSOR, HYDROLASE, METAL-BINDING, PROTEASE, SECRETED, SERINE PROTEASE, SPORULATION, ZYMOGEN
3mpw:H (LEU12) to (PRO76) STRUCTURE OF EUTM IN 2-D PROTEIN MEMBRANE | BACTERIAL MICROCOMPARTMENT, SHELL PROTEIN, ETHANOLAMINE AMMONIA LYASE, CARBOXYSOME, MEMBRANE PROTEIN
3mpw:B (LEU12) to (PRO76) STRUCTURE OF EUTM IN 2-D PROTEIN MEMBRANE | BACTERIAL MICROCOMPARTMENT, SHELL PROTEIN, ETHANOLAMINE AMMONIA LYASE, CARBOXYSOME, MEMBRANE PROTEIN
3mpw:F (LEU12) to (PRO76) STRUCTURE OF EUTM IN 2-D PROTEIN MEMBRANE | BACTERIAL MICROCOMPARTMENT, SHELL PROTEIN, ETHANOLAMINE AMMONIA LYASE, CARBOXYSOME, MEMBRANE PROTEIN
5euh:A (HIS390) to (THR469) CRYSTAL STRUCTURE OF THE C-DI-GMP-BOUND GGDEF DOMAIN OF P. FLUORESCENS GCBC | DIGUANYLATE CYCLASE, SECOND MESSENGER, BIOFILM FORMATION, SIGNALING, MEMBRANE PROTEIN
5euh:B (GLY389) to (THR469) CRYSTAL STRUCTURE OF THE C-DI-GMP-BOUND GGDEF DOMAIN OF P. FLUORESCENS GCBC | DIGUANYLATE CYCLASE, SECOND MESSENGER, BIOFILM FORMATION, SIGNALING, MEMBRANE PROTEIN
5exr:C (PRO971) to (LYS1045) CRYSTAL STRUCTURE OF HUMAN PRIMOSOME | HUMAN PRIMOSOME, COMPLEX, PRIMASE, DNA POLYMERASE ALPHA, PRIMER, DNA REPLICATION, DNA, RNA, REPLICASE, REPLICATION
5exr:G (PRO971) to (LYS1045) CRYSTAL STRUCTURE OF HUMAN PRIMOSOME | HUMAN PRIMOSOME, COMPLEX, PRIMASE, DNA POLYMERASE ALPHA, PRIMER, DNA REPLICATION, DNA, RNA, REPLICASE, REPLICATION
4qw8:A (GLU79) to (SER145) TERNARY CRYSTAL STRUCTURES OF A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH DNA AND D-DCTP | Y-FAMILY DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
4qw9:A (LYS78) to (SER145) TERNARY CRYSTAL STRUCTURES OF A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH DNA AND (-)FTC-PPNP | Y-FAMILY DNA POLYMERASE, TRANSFERASE-DNA COMPLEX, DPO4, POLYMERASE
4qwa:A (LYS78) to (SER145) TERNARY CRYSTAL STRUCTURES OF A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH DNA AND (-)3TC-DP | Y-FAMILY DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
4qwb:A (LYS78) to (SER145) CRYSTAL STRUCTURE OF DPO4 LINKER REGION P236A MUTANT WITH AN INCOMING D-DCDP | DBH, DPO4, POLYMERASE, TRANSFERASE-DNA COMPLEX
4qwd:A (LYS78) to (SER145) TERNARY CRYSTAL STRUCTURES OF A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH DNA AND (-)3TC-PPNP | Y-FAMILY DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
4qwe:A (LYS78) to (SER145) TERNARY CRYSTAL STRUCTURES OF A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH DNA AND (-)FTC-DP | Y-FAMILY DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
3bq0:A (PRO79) to (ALA146) PRE-INSERTION BINARY COMPLEX OF DBH DNA POLYMERASE | DNA POLYMERASE, Y-FAMILY, LESION BYPASS, SINGLE-BASE DELETION, -1 FRAMESHIFT, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE/DNA, TRANSFERASE-DNA COMPLEX
3bq1:A (LYS78) to (ALA146) INSERTION TERNARY COMPLEX OF DBH DNA POLYMERASE | DNA POLYMERASE, Y-FAMILY, LESION BYPASS, SINGLE-BASE DELETION, -1 FRAMESHIFT, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3bq2:A (PRO79) to (ALA146) POST-INSERTION BINARY COMPLEX OF DBH DNA POLYMERASE | DNA POLYMERASE, Y-FAMILY, LESION BYPASS, SINGLE-BASE DELETION, -1 FRAMESHIFT, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3br9:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, CYTOPLASM, HOST- VIRUS INTERACTION, ANTIVIRAL, VIRAL NUCLEOPROTEIN, HYDROLASE
3br9:B (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, CYTOPLASM, HOST- VIRUS INTERACTION, ANTIVIRAL, VIRAL NUCLEOPROTEIN, HYDROLASE
3bsa:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN
3mw1:A (SER61) to (GLU160) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH SMALL MOLECULE INHIBITOR | P38 MAP KINASE, TRANSFERASE, INHIBITOR COMPLEX, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3mwv:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE | HCV VIRUS RDRP NS5B POLYMERASE, TRANSFERASE
3mwv:B (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE | HCV VIRUS RDRP NS5B POLYMERASE, TRANSFERASE
3mww:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE | HCV VIRUS RDRP NS5B POLYMERASE INHIBITOR, TRANSFERASE
3mww:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE | HCV VIRUS RDRP NS5B POLYMERASE INHIBITOR, TRANSFERASE
5f5w:B (ASN35) to (VAL111) CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT OF GLYCYL TRNA SYNTHETASE (GLYRS) FROM AQUIFEX AEOLICUS IN COMPLEX WITH AN ANALOG OF GLYCYL ADENYLATE (GLY-SA) | CLASS II TRNA SYNTHETASE, LIGASE
5f5w:C (ASN35) to (VAL111) CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT OF GLYCYL TRNA SYNTHETASE (GLYRS) FROM AQUIFEX AEOLICUS IN COMPLEX WITH AN ANALOG OF GLYCYL ADENYLATE (GLY-SA) | CLASS II TRNA SYNTHETASE, LIGASE
5f5w:E (ASN35) to (VAL111) CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT OF GLYCYL TRNA SYNTHETASE (GLYRS) FROM AQUIFEX AEOLICUS IN COMPLEX WITH AN ANALOG OF GLYCYL ADENYLATE (GLY-SA) | CLASS II TRNA SYNTHETASE, LIGASE
3bv0:A (LEU356) to (ARG403) CRYSTAL STRUCTURE OF PLP BOUND 7,8-DIAMINOPELARGONIC ACID SYNTHASE IN MYCOBACTERIUM TUBERCULOSIS | AMINOTRANSFERASE, BIOTIN BIOSYNTHESIS, PYRIDOXAL PHOSPHATE, S- ADENOSYL-L-METHIONINE, TRANSFERASE
4qza:A (ARG305) to (GLU386) MOUSE TDT IN COMPLEX WITH A DSB SUBSTRATE, C-C BASE PAIR | TERMINAL DEOXYNUCLEOTIDYLTRANSFERASE, NUCLEUS, TRANSFERASE-DNA COMPLEX
4qzb:A (ARG305) to (GLU386) MOUSE TDT IN COMPLEX WITH A DSB SUBSTRATE, C-T BASE PAIR | TERMINAL DEOXYNUCLEOTIDYLTRANSFERASE, NUCLEUS, TRANSFERASE-DNA COMPLEX
4qzf:A (ARG305) to (ILE380) MOUSE TDT, F401A MUTANT, IN COMPLEX WITH A DSB SUBSTRATE, C-A BASE PAIR | TERMINAL DEOXYNUCLEOTIDYLTRANSFERASE, NUCLEUS, TRANSFERASE-DNA COMPLEX
4r0e:A (THR293) to (PRO356) CRYSTAL STRUCTURE OF THE POLIOVIRUS RNA-DEPENDENT RNA POLYMERASE LOW- FIDELITY MUTANT 3DPOL H273R | RNA-DEPENDENT RNA POLYMERASE, FIDELITY, LOW-FIDELITY, RNA POLYMERASE, POLIOVIRUS, TRANSFERASE
3c1n:A (GLY333) to (ASP403) CRYSTAL STRUCTURE OF ALLOSTERIC INHIBITION THREONINE-SENSITIVE ASPARTOKINASE FROM METHANOCOCCUS JANNASCHII WITH L-THREONINE | KINASE, ALLOSTERIC INHIBITION, THREONINE-SENSITIVE, ACT DOMAIN, AMINO-ACID BIOSYNTHESIS, THREONINE BIOSYNTHESIS, TRANSFERASE
4bwk:A (GLU312) to (ASN418) STRUCTURE OF NEUROSPORA CRASSA PAN3 PSEUDOKINASE | GENE REGULATION, DEADENYLASE, PAN2, MIRNA, MRNA DECAY
4bwk:B (GLU312) to (ASN418) STRUCTURE OF NEUROSPORA CRASSA PAN3 PSEUDOKINASE | GENE REGULATION, DEADENYLASE, PAN2, MIRNA, MRNA DECAY
3nah:A (PRO332) to (GLN386) CRYSTAL STRUCTURES AND FUNCTIONAL ANALYSIS OF MURINE NOROVIRUS RNA- DEPENDENT RNA POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, MURINE NOROVIRUS, TRANSFERASE
3nah:B (PRO332) to (GLN386) CRYSTAL STRUCTURES AND FUNCTIONAL ANALYSIS OF MURINE NOROVIRUS RNA- DEPENDENT RNA POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, MURINE NOROVIRUS, TRANSFERASE
3nah:C (ASP331) to (GLN386) CRYSTAL STRUCTURES AND FUNCTIONAL ANALYSIS OF MURINE NOROVIRUS RNA- DEPENDENT RNA POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, MURINE NOROVIRUS, TRANSFERASE
3cb4:C (LEU415) to (PHE472) THE CRYSTAL STRUCTURE OF LEPA | GTPASE, OB-FOLD, GTP-BINDING, MEMBRANE, NUCLEOTIDE-BINDING, TRANSLATION
4r8u:A (PHE77) to (ALA144) S-SAD STRUCTURE OF DINB-DNA COMPLEX | NUCLEOTIDYL TRANSFERASE, DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
4r8u:B (ASP78) to (ALA144) S-SAD STRUCTURE OF DINB-DNA COMPLEX | NUCLEOTIDYL TRANSFERASE, DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
4rbt:B (LEU14) to (PRO78) PDUA K26A S40L MUTANT, FROM SALMONELLA ENTERICA SEROVAR TYPHIMURIUM LT2 | BACTERIAL MICROCOMPARTMENT SHELL PROTEIN, STRUCTURAL PROTEIN
4rbt:C (LEU14) to (PRO78) PDUA K26A S40L MUTANT, FROM SALMONELLA ENTERICA SEROVAR TYPHIMURIUM LT2 | BACTERIAL MICROCOMPARTMENT SHELL PROTEIN, STRUCTURAL PROTEIN
5fku:A (ARG1100) to (SER1152) CRYO-EM STRUCTURE OF THE E. COLI REPLICATIVE DNA POLYMERASE COMPLEX IN DNA FREE STATE (DNA POLYMERASE III ALPHA, BETA, EPSILON, TAU COMPLEX) | TRANSFERASE, DNA REPLICATION, DNA POLYMERASE III ALPHA, DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, DNA POLYMERASE III TAU
3ne5:A (TYR67) to (ASP132) CRYSTAL STRUCTURE OF THE CUSBA HEAVY-METAL EFFLUX COMPLEX FROM ESCHERICHIA COLI | TRANSMEMBRANE HELIX, METAL TRANSPORT
3ng0:A (ASP189) to (PHE258) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SYNECHOCYSTIS SP. PCC 6803 | GLUTAMINE SYNTHETASE TYPE I, GSI, NITROGEN METABOLISM, SYNECHOCYSTIS, LIGASE
4c3k:B (ASP14) to (ARG101) STRUCTURE OF MIXED PII-ADP COMPLEXES FROM S. ELONGATUS | TRANSCRIPTION
5flm:A (THR1227) to (HIS1310) STRUCTURE OF TRANSCRIBING MAMMALIAN RNA POLYMERASE II | TRANSCRIPTION, ELONGATION
3ngk:A (LEU14) to (PRO78) PDUA FROM SALMONELLA ENTERICA TYPHIMURIUM | BMC SHELL PROTEIN, PDU, CARBOXYSOME, PROPANEDIOL, UNKNOWN FUNCTION
3ciz:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3ciz:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3cj0:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj0:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
4c4h:A (ASP561) to (ASP657) STRUCTURE-BASED DESIGN OF ORALLY BIOAVAILABLE PYRROLOPYRIDINE INHIBITORS OF THE MITOTIC KINASE MPS1 | TRANSFERASE, PROTEIN KINASE, MITOSIS, STRUCTURE-BASED DESIGN
4c4j:A (ASP561) to (ASP657) STRUCTURE-BASED DESIGN OF ORALLY BIOAVAILABLE PYRROLOPYRIDINE INHIBITORS OF THE MITOTIC KINASE MPS1 | TRANSFERASE, MITOSIS, STRUCTURE-BASED DRUG DESIGN
3cj3:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj3:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj4:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj4:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj5:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj5:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3nnu:A (SER61) to (GLU160) CRYSTAL STRUCTURE OF P38 ALPHA IN COMPLEX WITH DP1376 | KINASE, TRANSFERASE
4c9t:A (ARG22) to (LEU140) BACTERIAL CHALCONE ISOMERASE IN OPEN CONFORMATION FROM EUBACTERIUM RAMULUS AT 2.0 A RESOLUTION, SELENOMET DERIVATIVE | ISOMERASE, FLAVONOIDS
4c9t:B (ARG22) to (LEU140) BACTERIAL CHALCONE ISOMERASE IN OPEN CONFORMATION FROM EUBACTERIUM RAMULUS AT 2.0 A RESOLUTION, SELENOMET DERIVATIVE | ISOMERASE, FLAVONOIDS
4c9t:D (ARG22) to (LEU140) BACTERIAL CHALCONE ISOMERASE IN OPEN CONFORMATION FROM EUBACTERIUM RAMULUS AT 2.0 A RESOLUTION, SELENOMET DERIVATIVE | ISOMERASE, FLAVONOIDS
4c9t:E (ARG22) to (LEU140) BACTERIAL CHALCONE ISOMERASE IN OPEN CONFORMATION FROM EUBACTERIUM RAMULUS AT 2.0 A RESOLUTION, SELENOMET DERIVATIVE | ISOMERASE, FLAVONOIDS
4c9t:F (ARG22) to (LEU140) BACTERIAL CHALCONE ISOMERASE IN OPEN CONFORMATION FROM EUBACTERIUM RAMULUS AT 2.0 A RESOLUTION, SELENOMET DERIVATIVE | ISOMERASE, FLAVONOIDS
3ns5:B (VAL92) to (THR159) CRYSTAL STRUCTURE OF THE RNA RECOGNITION MOTIF OF YEAST EIF3B RESIDUES 76-161 | TRANSLATION
3ns6:A (PHE103) to (THR159) CRYSTAL STRUCTURE OF HTE RNA RECOGNITION MOTIF OF YEAST EIF3B RESIDUES 76-170 | TRANSLATION
3ns6:B (VAL92) to (THR159) CRYSTAL STRUCTURE OF HTE RNA RECOGNITION MOTIF OF YEAST EIF3B RESIDUES 76-170 | TRANSLATION
3cnq:P (SER22) to (GLU70) PROSUBTILISIN SUBSTRATE COMPLEX OF SUBTILISIN SUBT_BACAM | UNCLEAVED, PROENZYME, SUBSTRATE COMPLEX, HYDROLASE, METAL- BINDING, PROTEASE, SECRETED, SERINE PROTEASE, SPORULATION, ZYMOGEN
4rpf:A (PHE242) to (ILE297) CRYSTAL STRUCTURE OF HOMOSERINE KINASE FROM YERSINIA PESTIS NEPAL516, NYSGRC TARGET 032715 | PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, TRANSFERASE, KINASE
4rpf:B (PHE242) to (ILE297) CRYSTAL STRUCTURE OF HOMOSERINE KINASE FROM YERSINIA PESTIS NEPAL516, NYSGRC TARGET 032715 | PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, TRANSFERASE, KINASE
4rpf:C (GLY241) to (ILE297) CRYSTAL STRUCTURE OF HOMOSERINE KINASE FROM YERSINIA PESTIS NEPAL516, NYSGRC TARGET 032715 | PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, TRANSFERASE, KINASE
4rq2:A (ARG152) to (GLU232) HUMAN DNA POLYMERASE BETA WITH GAPPED DNA CONTAINING AN 8-OXO-7,8- DIHYDRO-GUANINE (8-OXOG)AND DCTP SOAKED WITH MNCL2 FOR 35 S | X-FAMILY, POL BETA, TRANSFERASE-DNA COMPLEX
3cso:A (VAL284) to (TYR358) HCV POLYMERASE IN COMPLEX WITH A 1,5 BENZODIAZEPINE INHIBITOR | 1,5-BENZODIAZEPINES, HEPATITIS C VIRUS, NS5B, POLYMERASE, TRANSFERASE
3cso:B (THR286) to (TYR358) HCV POLYMERASE IN COMPLEX WITH A 1,5 BENZODIAZEPINE INHIBITOR | 1,5-BENZODIAZEPINES, HEPATITIS C VIRUS, NS5B, POLYMERASE, TRANSFERASE
4rua:A (LYS78) to (SER145) CRYSTAL STRUCTURE OF Y-FAMILY DNA POLYMERASE DPO4 BYPASSING A MEFAPY- DG ADDUCT | PROTEIN, DNA, DNA DAMAGE, DNA-DIRECTED DNA POLYMERASE, ADENOSINE TRIPHOSPHATE, Y-FAMILY POLYMERASE, TRANS-LESION SYNTHESIS (TLS), DNA BINDING, MEFAPY-DG LESION BYPASS, 2,6-DIAMINO-4-HYDROXY N(5)- (METHYL)-FORMAMIDOPYRIMIDINE (MEFAPY-DG) LESION, TRANSFERASE-DNA COMPLEX
4ruc:A (LYS78) to (SER145) CRYSTAL STRUCTURE OF Y-FAMILY DNA POLYMERASE DPO4 EXTENDING FROM A MEFAPY-DG:DC PAIR | PROTEIN, DNA, DNA DAMAGE, DNA-DIRECTED DNA POLYMERASE, ADENOSINE TRIPHOSPHATE, Y-FAMILY POLYMERASE, TRANS-LESION SYNTHESIS (TLS), DNA BINDING, MEFAPY-DG LESION BYPASS, PRIMER EXTENSION, 2,6-DIAMINO-4- HYDROXY N(5)-(METHYL)-FORMAMIDOPYRIMIDINE (MEFAPY-DG) LESION, TRANSFERASE-DNA COMPLEX
4rvo:A (MSE343) to (LEU412) CRYSTAL STRUCTURE OF A PUTATIVE ACYL-COA LIGASE (BT_0428) FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 AT 2.41 A RESOLUTION | ACETYL-COA SYNTHETASE-LIKE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, LIGASE
3cwj:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, HEPATITIS, TRANSFERASE, VIRAL PROTEIN
3cwj:B (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, HEPATITIS, TRANSFERASE, VIRAL PROTEIN
4cls:A (ARG66) to (GLY150) CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE WITH PYROPHOSPHATE | LYASE, NUCLEOTIDE-BINDING
4clt:A (ARG66) to (GLY150) CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE WITH ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE AND PYROPHOSPHATE | LYASE
4clu:A (ARG66) to (GLY150) CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE WITH PYROPHOSPHATE | LYASE, REACTION
4clw:A (ARG66) to (GLY150) CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE IN COMPLEX WITH ALPHA,BETA-METHYLENEADENOSINE-5'-TRIPHOSPHATE SOAKED WITH BISULFITE | LYASE, NUCLEOTIDE-BINDING
4clz:A (ARG66) to (ALA149) CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE WITH INHIBITOR 4,4'-DIISOTHIOCYANO-2,2'-STILBENEDISULFONIC ACID | LYASE, NUCLEOTIDE-BINDING
4ry4:A (THR287) to (TYR358) C-TERMINAL MUTANT (Y448F) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4ry4:B (THR287) to (TYR358) C-TERMINAL MUTANT (Y448F) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4ry5:A (THR287) to (TYR358) C-TERMINAL MUTANT (W550N) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4ry5:B (THR287) to (TYR358) C-TERMINAL MUTANT (W550N) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4ry7:B (THR287) to (TYR358) C-TERMINAL MUTANT (D559E) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4rz3:B (ALA77) to (GLY141) CRYSTAL STRUCTURE OF THE MIND-LIKE ATPASE FLHG | P-LOOP, WALKER A, SIMIBI, FLAGELLUM, CELL DIVISION, STRUCTURAL PROTEIN
4cny:A (LEU13) to (ASP95) STRUCTURE OF PII SIGNALING PROTEIN GLNZ FROM AZOSPIRILLUM BRASILENSE | SIGNALING PROTEIN, GLNK-LIKE
4cnz:A (LEU13) to (ASP95) STRUCTURE OF PII SIGNALING PROTEIN GLNZ FROM AZOSPIRILLUM BRASILENSE IN COMPLEX WITH ADENOSINE DIPHOSPHATE | SIGNALING PROTEIN, GLNK-LIKE,
4cnz:B (LEU13) to (ASP95) STRUCTURE OF PII SIGNALING PROTEIN GLNZ FROM AZOSPIRILLUM BRASILENSE IN COMPLEX WITH ADENOSINE DIPHOSPHATE | SIGNALING PROTEIN, GLNK-LIKE,
4cnz:C (LEU13) to (ASP95) STRUCTURE OF PII SIGNALING PROTEIN GLNZ FROM AZOSPIRILLUM BRASILENSE IN COMPLEX WITH ADENOSINE DIPHOSPHATE | SIGNALING PROTEIN, GLNK-LIKE,
4cnz:D (LEU13) to (ASP95) STRUCTURE OF PII SIGNALING PROTEIN GLNZ FROM AZOSPIRILLUM BRASILENSE IN COMPLEX WITH ADENOSINE DIPHOSPHATE | SIGNALING PROTEIN, GLNK-LIKE,
4co0:B (LEU13) to (ASP95) STRUCTURE OF PII SIGNALING PROTEIN GLNZ FROM AZOSPIRILLUM BRASILENSE IN COMPLEX WITH ADENOSINE DIPHOSPHATE | SIGNALING PROTEIN, GLNK-LIKE
4co1:B (LEU13) to (ASP95) STRUCTURE OF PII SIGNALING PROTEIN GLNZ FROM AZOSPIRILLUM BRASILENSE IN COMPLEX WITH ADENOSINE DIPHOSPHATE | SIGNALING PROTEIN, GLNK-LIKE
4co4:B (LEU13) to (ASP95) STRUCTURE OF PII SIGNALING PROTEIN GLNZ FROM AZOSPIRILLUM BRASILENSE IN COMPLEX WITH ADENOSINE TRIPHOSPHATE | SIGNALING PROTEIN, GLNK-LIKE
4co4:C (LEU13) to (ASP95) STRUCTURE OF PII SIGNALING PROTEIN GLNZ FROM AZOSPIRILLUM BRASILENSE IN COMPLEX WITH ADENOSINE TRIPHOSPHATE | SIGNALING PROTEIN, GLNK-LIKE
4s0r:B (GLU166) to (PHE231) STRUCTURE OF GS-TNRA COMPLEX | GLUTAMINE SYNTHESIS, TRANSCRIPTION REGULATION, CHAPERONE, LIGASE
4s0r:E (GLY165) to (PHE231) STRUCTURE OF GS-TNRA COMPLEX | GLUTAMINE SYNTHESIS, TRANSCRIPTION REGULATION, CHAPERONE, LIGASE
4s17:B (GLN197) to (PHE263) THE CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM BIFIDOBACTERIUM ADOLESCENTIS ATCC 15703 | STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, LIGASE
3d28:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL BENZISOTHIAZOLE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEOTIDE-BINDING, TRANSCRIPTION, HYDROLASE, TRANSFERASE
3d28:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL BENZISOTHIAZOLE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEOTIDE-BINDING, TRANSCRIPTION, HYDROLASE, TRANSFERASE
3d5m:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA POLYMERASE, RNA REPLICATION, RNA-BINDING, TRANSCRIPTION, NUCLEOTIDYLTRANSFERASE, HYDROLASE
3d5m:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA POLYMERASE, RNA REPLICATION, RNA-BINDING, TRANSCRIPTION, NUCLEOTIDYLTRANSFERASE, HYDROLASE
4cti:B (LEU434) to (LEU521) ESCHERICHIA COLI ENVZ HISTIDINE KINASE CATALYTIC PART FUSED TO ARCHAEOGLOBUS FULGIDUS AF1503 HAMP DOMAIN | SIGNALING PROTEIN, TWO-COMPONENT SIGNAL TRANSDUCTION, TCST, DHP DOMAIN, CA DOMAIN, PHOSPHORYL TRANSFER, STUTTER
4cti:D (HIS432) to (LEU521) ESCHERICHIA COLI ENVZ HISTIDINE KINASE CATALYTIC PART FUSED TO ARCHAEOGLOBUS FULGIDUS AF1503 HAMP DOMAIN | SIGNALING PROTEIN, TWO-COMPONENT SIGNAL TRANSDUCTION, TCST, DHP DOMAIN, CA DOMAIN, PHOSPHORYL TRANSFER, STUTTER
4tlr:A (THR287) to (TYR358) NS5B IN COMPLEX WITH LACTAM-THIOPHENE CARBOXYLIC ACIDS | COMPLEX POLYMERASE INHBITOR
3d83:A (SER61) to (GLU160) CRYSTAL STRUCTURE OF P38 KINASE IN COMPLEX WITH A BIPHENYL AMIDE INHIBITOR | P38, SERINE/THREONINE PROTEIN KINASE, MAP KINASE, ATP-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE
3obj:A (SER61) to (GLU160) CONFORMATIONAL PLASTICITY OF P38 MAP KINASE DFG MUTANTS IN RESPONSE TO INHIBITOR BINDING | TRANSFERASE
3ddn:A (GLY466) to (SER529) CRYSTAL STRUCTURE OF HYDROXYPYRUVIC ACID PHOSPHATE BOUND D-3- PHOSPHOGLYCERATE DEHYDROGENASE IN MYCOBACTERIUM TUBERCULOSIS | OXIDOREDUCTASE, PHOSPHOGLYCERATE DEHYDROGENASE, SERINE BIOSYNTHESIS, AMINO-ACID BIOSYNTHESIS, NAD
3ofe:A (THR113) to (GLU166) STRUCTURED DOMAIN OF DROSOPHILA MELANOGASTER BOCA P41 2 2 CRYSTAL FORM | MESD, MOLECULAR CHAPERONE, PROTEIN FOLDING, YWTD PROPELLER, LRP, CHAPERONE
3off:A (THR113) to (GLU166) STRUCTURED DOMAIN OF DROSOPHILA MELANOGASTER BOCA P65 2 2 CRYSTAL FORM | MESD, MOLECULAR CHAPERONE, PROTEIN FOLDING, YWTD PROPELLER, LRP, CHAPERONE
3ofh:A (THR124) to (GLU177) STRUCTURED DOMAIN OF MUS MUSCULUS MESD | MESD, MOLECULAR CHAPERONE, PROTEIN FOLDING, YWTD PROPELLER, LRP, CHAPERONE
4tqr:A (LYS78) to (SER145) TERNARY COMPLEX OF Y-FAMILY DNA POLYMERASE DPO4 WITH (5'S)-8,5'-CYCLO- 2'-DEOXYGUANOSINE AND DTTP | Y FAMILY DNA POLYMERASE, DNA DAMAGE, CYCLOPURINE, TRANSLESION SYNTHESIS
4tqs:A (LYS78) to (SER145) TERNARY COMPLEX OF Y-FAMILY DNA POLYMERASE DPO4 WITH (5'S)-8,5'-CYCLO- 2'-DEOXYGUANOSINE AND DCTP | Y-FAMILY DNA POLYMERASE, DNA DAMAGE, CYCLOPURINE, TRANSLESION DNA SYNTHESIS, TRANSFERASE
4tqs:B (LYS78) to (SER145) TERNARY COMPLEX OF Y-FAMILY DNA POLYMERASE DPO4 WITH (5'S)-8,5'-CYCLO- 2'-DEOXYGUANOSINE AND DCTP | Y-FAMILY DNA POLYMERASE, DNA DAMAGE, CYCLOPURINE, TRANSLESION DNA SYNTHESIS, TRANSFERASE
4d06:B (ARG22) to (LEU140) BACTERIAL CHALCONE ISOMERASE COMPLEXED WITH NARINGENIN | ISOMERASE, BACTERIAL CHALCONE ISOMERASE, FLAVONOIDS, NARINGENIN
4d06:D (ARG22) to (LEU140) BACTERIAL CHALCONE ISOMERASE COMPLEXED WITH NARINGENIN | ISOMERASE, BACTERIAL CHALCONE ISOMERASE, FLAVONOIDS, NARINGENIN
4d4f:C (ARG22) to (LEU140) MUTANT P250A OF BACTERIAL CHALCONE ISOMERASE FROM EUBACTERIUM RAMULUS | ISOMERASE, FLAVONOIDS, NON-PROLYL CIS-PEPTIDE
4d4f:D (ARG22) to (LEU140) MUTANT P250A OF BACTERIAL CHALCONE ISOMERASE FROM EUBACTERIUM RAMULUS | ISOMERASE, FLAVONOIDS, NON-PROLYL CIS-PEPTIDE
4d4f:E (ARG22) to (LEU140) MUTANT P250A OF BACTERIAL CHALCONE ISOMERASE FROM EUBACTERIUM RAMULUS | ISOMERASE, FLAVONOIDS, NON-PROLYL CIS-PEPTIDE
4txs:A (SER288) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, TETRAMER, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4txs:B (THR287) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, TETRAMER, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4txs:C (THR287) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, TETRAMER, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4txs:D (THR287) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, TETRAMER, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3dn9:A (PHE13) to (ALA79) CARBOXYSOME SUBUNIT, CCMK1 C-TERMINAL DELETION MUTANT | HEXAMER, STRUCTURAL PROTEIN
3dn9:B (PHE13) to (ALA79) CARBOXYSOME SUBUNIT, CCMK1 C-TERMINAL DELETION MUTANT | HEXAMER, STRUCTURAL PROTEIN
3dn9:C (PHE13) to (ALA79) CARBOXYSOME SUBUNIT, CCMK1 C-TERMINAL DELETION MUTANT | HEXAMER, STRUCTURAL PROTEIN
3dn9:D (PHE13) to (ALA79) CARBOXYSOME SUBUNIT, CCMK1 C-TERMINAL DELETION MUTANT | HEXAMER, STRUCTURAL PROTEIN
3dn9:E (PHE13) to (ALA79) CARBOXYSOME SUBUNIT, CCMK1 C-TERMINAL DELETION MUTANT | HEXAMER, STRUCTURAL PROTEIN
3dn9:F (PHE13) to (ALA79) CARBOXYSOME SUBUNIT, CCMK1 C-TERMINAL DELETION MUTANT | HEXAMER, STRUCTURAL PROTEIN
3dnc:A (PHE13) to (ALA79) CARBOXYSOME SHELL PROTEIN, CCMK2 C-TERMINAL DELETION MUTANT, WITH A CLOSER SPACING BETWEEN HEXAMERS | HEXAMER, STRUCTURAL PROTEIN
4ty8:B (CYS289) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ty8:C (THR286) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ty8:D (THR287) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ty9:A (THR287) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANAFERASE-TRANSFERASE INHIBITOR COMPLEX
4ty9:B (THR287) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANAFERASE-TRANSFERASE INHIBITOR COMPLEX
4ty9:C (THR287) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANAFERASE-TRANSFERASE INHIBITOR COMPLEX
4ty9:D (VAL284) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANAFERASE-TRANSFERASE INHIBITOR COMPLEX
4tya:A (THR287) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4tya:B (THR287) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4tya:D (THR286) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4tyb:A (THR286) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4tyb:B (THR286) to (HIS374) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4tyb:C (THR286) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4tyb:D (THR287) to (TYR358) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3or1:B (ILE224) to (ASP275) CRYSTAL STRUCTURE OF DISSIMILATORY SULFITE REDUCTASE I (DSRI) | DISSIMILATORY SULFITE REDUCTASE, SULFATE REDUCTION, OXIDOREDUCTASE, SULFITE REDUCTION
3or1:E (ILE224) to (ASP275) CRYSTAL STRUCTURE OF DISSIMILATORY SULFITE REDUCTASE I (DSRI) | DISSIMILATORY SULFITE REDUCTASE, SULFATE REDUCTION, OXIDOREDUCTASE, SULFITE REDUCTION
3or2:B (ILE224) to (ASP275) CRYSTAL STRUCTURE OF DISSIMILATORY SULFITE REDUCTASE II (DSRII) | DISSIMILATORY SULFITE REDUCTASE, SULFATE REDUCTION, OXIDOREDUCTASE
3or2:E (ILE224) to (ASP275) CRYSTAL STRUCTURE OF DISSIMILATORY SULFITE REDUCTASE II (DSRII) | DISSIMILATORY SULFITE REDUCTASE, SULFATE REDUCTION, OXIDOREDUCTASE
3otb:A (ARG49) to (PRO135) CRYSTAL STRUCTURE OF HUMAN TRNAHIS GUANYLYLTRANSFERASE (THG1) - DGTP COMPLEX | GUANYLYLTRANSFERASE, POLYMERASE-LIKE PALM DOMAIN, CATALYTIC CARBOXYLATES, TRANSFERASE
3otb:B (ARG49) to (PRO135) CRYSTAL STRUCTURE OF HUMAN TRNAHIS GUANYLYLTRANSFERASE (THG1) - DGTP COMPLEX | GUANYLYLTRANSFERASE, POLYMERASE-LIKE PALM DOMAIN, CATALYTIC CARBOXYLATES, TRANSFERASE
3otc:A (ASP47) to (PRO135) CRYSTAL STRUCTURE OF HUMAN TRNAHIS GUANYLYLTRANSFERASE (THG1)- NATIVE II | GUANYLYLTRANSFERASE, POLYMERASE-LIKE PALM DOMAIN, CATALYTIC CARBOXYLATES, TRANSFERASE
3otc:B (ASP47) to (PRO135) CRYSTAL STRUCTURE OF HUMAN TRNAHIS GUANYLYLTRANSFERASE (THG1)- NATIVE II | GUANYLYLTRANSFERASE, POLYMERASE-LIKE PALM DOMAIN, CATALYTIC CARBOXYLATES, TRANSFERASE
3ote:A (ARG49) to (PRO135) CRYSTAL STRUCTURE OF HUMAN TRNAHIS GUANYLYLTRANSFERASE (THG1)- NATIVE I | GUANYLYLTRANSFERASE, POLYMERASE-LIKE PALM DOMAIN, CATALYTIC CARBOXYLATES, TRANSFERASE
3ote:B (ASP47) to (PRO135) CRYSTAL STRUCTURE OF HUMAN TRNAHIS GUANYLYLTRANSFERASE (THG1)- NATIVE I | GUANYLYLTRANSFERASE, POLYMERASE-LIKE PALM DOMAIN, CATALYTIC CARBOXYLATES, TRANSFERASE
4dez:A (PRO80) to (SER145) STRUCTURE OF MSDPO4 | Y-FAMILY, DNA POLYMERASE, TRANSFERASE
4dfj:A (PHE769) to (GLY824) CRYSTAL STRUCTURE OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS IN A CLOSED TERNARY COMPLEX WITH 5-(AMINOPENTINYL)- DTTP | DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
4dj2:A (THR201) to (ARG300) UNWINDING THE DIFFERENCES OF THE MAMMALIAN PERIOD CLOCK PROTEINS FROM CRYSTAL STRUCTURE TO CELLULAR FUNCTION | PAS DOMAINS, CIRCADIAN CLOCK PROTEIN, PROTEIN BINDING
4dj2:B (THR201) to (PHE298) UNWINDING THE DIFFERENCES OF THE MAMMALIAN PERIOD CLOCK PROTEINS FROM CRYSTAL STRUCTURE TO CELLULAR FUNCTION | PAS DOMAINS, CIRCADIAN CLOCK PROTEIN, PROTEIN BINDING
4djb:A (ILE24) to (ASP112) A STRUCTURAL BASIS FOR THE ASSEMBLY AND FUNCTIONS OF A VIRAL POLYMER THAT INACTIVATES MULTIPLE TUMOR SUPPRESSORS | ADENOVIRUS PROTEIN, RRM-LIKE FOLD, HPV E2 DBD-LIKE PROTEIN, TUMOR SUPPRESSOR INACTIVATION, NUCLEUS, VIRAL PROTEIN
3p23:A (ASP610) to (PRO699) CRYSTAL STRUCTURE OF THE HUMAN KINASE AND RNASE DOMAINS IN COMPLEX WITH ADP | KINASE DOMAIN, KINASE AND RNASE FUNCTION, ATP BINDING SSRNA BINDING, DEPHOSPHORYLATED, HYDROLASE, TRANSFERASE
3p23:C (ASP610) to (PRO699) CRYSTAL STRUCTURE OF THE HUMAN KINASE AND RNASE DOMAINS IN COMPLEX WITH ADP | KINASE DOMAIN, KINASE AND RNASE FUNCTION, ATP BINDING SSRNA BINDING, DEPHOSPHORYLATED, HYDROLASE, TRANSFERASE
4dli:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH RL87 | MAP KINASE INSERT, TRANSFERASE, LIPID BINDING POCKET, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4dlj:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH RL163 | MAP KINASE INSERT, TRANSFERASE, LIPID BINDING POCKET, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4dn0:A (GLY355) to (ASP430) PELD 156-455 FROM PSEUDOMONAS AERUGINOSA PA14 IN COMPLEX WITH C-DI-GMP | GAF DOMAIN, GGDEF DOMAIN, C-DI-GMP RECEPTOR, BACTERIAL INNER MEMBRANE, NUCLEOTIDE-BINDING PROTEIN
3p5t:L (THR93) to (PRO158) CFIM25-CFIM68 COMPLEX | RRM DOMAIN, POLY(A) SITE RECOGNITION, RNA, NUCLEAR, RNA BINDING PROTEIN
3p5t:Q (THR93) to (PRO158) CFIM25-CFIM68 COMPLEX | RRM DOMAIN, POLY(A) SITE RECOGNITION, RNA, NUCLEAR, RNA BINDING PROTEIN
3p78:A (SER61) to (GLU160) P38 INHIBITOR-BOUND | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4dnt:A (TYR67) to (ASP132) CRYSTAL STRUCTURE OF THE CUSBA HEAVY-METAL EFFLUX COMPLEX FROM ESCHERICHIA COLI, MUTANT | BETA BARREL, TRANSPORT PROTEIN
4u8y:C (THR62) to (LYS131) COUPLING OF REMOTE ALTERNATING-ACCESS TRANSPORT MECHANISMS FOR PROTONS AND SUBSTRATES IN THE MULTIDRUG EFFLUX PUMP ACRB | MEMBRANE PROTEIN, TRANSPORT PROTEIN, DARPIN, MULTIDRUG EFFLUX PROTEIN
4dop:A (TYR67) to (LEU129) CRYSTAL STRUCTURE OF THE CUSBA HEAVY-METAL EFFLUX COMPLEX FROM ESCHERICHIA COLI, R MUTANT | BETA BARREL, TRANSPORT PROTEIN
4dpt:A (GLN259) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH INHIBITOR 6-FMVAPP AND ATPGS | GHMP KINASE FAMILY, LYASE-LYASE INHIBITOR COMPLEX
4dpt:B (GLN259) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH INHIBITOR 6-FMVAPP AND ATPGS | GHMP KINASE FAMILY, LYASE-LYASE INHIBITOR COMPLEX
4dpu:A (GLN259) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS S192A MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH INHIBITOR 6-FMVAPP AND ATPGS | GHMP KINASE FAMILY, LYASE-LYASE INHIBITOR COMPLEX
4dpx:B (GLN259) to (ASP317) CRYSTAL STRUCTURE OF S192A STAPHYLOCOCCUS EPIDERMIDIS MEVALONATE DIPHOSPHATE DECARBOXYLASE | GHMP KINASE FAMILY, LYASE
4dpy:A (GLU260) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS S192A MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH INHIBITOR DPGP | GHMP KINASE FAMILY, LYASE-LYASE INHIBITOR COMPLEX
4dpy:B (GLN259) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS S192A MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH INHIBITOR DPGP | GHMP KINASE FAMILY, LYASE-LYASE INHIBITOR COMPLEX
4dq2:A (SER93) to (TRP177) STRUCTURE OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE IN COMPLEX WITH BIOTINOL-5'-AMP | DNA BINDING DOMAIN, METABOLISM, BIOTIN, LIGATE, LIGASE
4dru:A (THR286) to (TYR358) HCV NS5B IN COMPLEX WITH MACROCYCLIC INDOLE INHIBITOR | HCV POLYMERASE, MACROCYCLE INHIBITOR, THUMB DOMAIN, TRANSFERASE- INHIBITOR COMPLEX
4dru:B (THR287) to (TYR358) HCV NS5B IN COMPLEX WITH MACROCYCLIC INDOLE INHIBITOR | HCV POLYMERASE, MACROCYCLE INHIBITOR, THUMB DOMAIN, TRANSFERASE- INHIBITOR COMPLEX
3pcq:C (THR14) to (LEU68) FEMTOSECOND X-RAY PROTEIN NANOCRYSTALLOGRAPHY | MEMBRANE PROTEIN, MULTIPROTEIN-PIGMENT COMPLEX, PHOTOSYNTHESIS
4ud5:A (ASP59) to (GLN136) STRUCTURAL PLASTICITY OF CID1 PROVIDES A BASIS FOR ITS RNA TERMINAL URIDYLYL TRANSFERASE ACTIVITY | TRANSFERASE, CAFFEINE, URIDYLYLTRANSFERASE ENZYME
3e51:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEOTIDE-BINDING, TRANSCRIPTION, TRANSFERASE
3e51:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEOTIDE-BINDING, TRANSCRIPTION, TRANSFERASE
4du7:A (GLN259) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH SUBSTRATE MEVALONATE DIPHOSPHATE | GHMP KINASE FAMILY, LYASE
4du7:B (GLN259) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH SUBSTRATE MEVALONATE DIPHOSPHATE | GHMP KINASE FAMILY, LYASE
4du8:A (GLN259) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS D283A MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH INHIBITOR DPGP | GHMP KINASE FAMILY, LYASE-LYASE INHIBITOR COMPLEX
3pfl:A (GLY528) to (VAL603) CRYSTAL STRUCTURE OF PFL FROM E.COLI IN COMPLEX WITH SUBSTRATE ANALOGUE OXAMATE | GLYCYL RADICAL ENZYME, TRANSFERASE, GLUCOSE METABOLISM, LYASE/TRANSFERASE COMPLEX
3pfl:B (GLY528) to (VAL603) CRYSTAL STRUCTURE OF PFL FROM E.COLI IN COMPLEX WITH SUBSTRATE ANALOGUE OXAMATE | GLYCYL RADICAL ENZYME, TRANSFERASE, GLUCOSE METABOLISM, LYASE/TRANSFERASE COMPLEX
3pg3:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH RL182 | DFG-OUT, SAR, KINASE DOMAIN, THIAZOLE-UREA, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3phe:A (THR286) to (TYR358) HCV NS5B WITH A BOUND QUINOLONE INHIBITOR | TRANSFERASE, POLYMERASE, RNA, MITOCHONDRIAL MEMBRANE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3phe:B (THR287) to (TYR358) HCV NS5B WITH A BOUND QUINOLONE INHIBITOR | TRANSFERASE, POLYMERASE, RNA, MITOCHONDRIAL MEMBRANE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3phe:C (THR287) to (TYR358) HCV NS5B WITH A BOUND QUINOLONE INHIBITOR | TRANSFERASE, POLYMERASE, RNA, MITOCHONDRIAL MEMBRANE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3phe:D (THR286) to (TYR358) HCV NS5B WITH A BOUND QUINOLONE INHIBITOR | TRANSFERASE, POLYMERASE, RNA, MITOCHONDRIAL MEMBRANE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
5i42:B (GLN161) to (HIS235) STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH A DNA APTAMER, AZTTP, AND CA(2+) ION | RT, DNA APTAMER, AZTTP, POLYMERASE, P SITE COMPLEX, 2-O- METHYLCYTIDINE, TRANSFERASE-DNA COMPLEX
5i42:D (GLN161) to (ASP237) STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH A DNA APTAMER, AZTTP, AND CA(2+) ION | RT, DNA APTAMER, AZTTP, POLYMERASE, P SITE COMPLEX, 2-O- METHYLCYTIDINE, TRANSFERASE-DNA COMPLEX
3pjx:A (GLY286) to (ALA365) STRUCTURE OF PSEUDOMONAS FLUORESCENCE LAPD GGDEF-EAL DUAL DOMAIN, P32 | GGDEF-EAL TANDEM DOMAIN, C-DI-GMP RECEPTOR, LYASE
4dx7:A (THR62) to (LYS131) TRANSPORT OF DRUGS BY THE MULTIDRUG TRANSPORTER ACRB INVOLVES AN ACCESS AND A DEEP BINDING POCKET THAT ARE SEPARATED BY A SWITCH-LOOP | DARPIN, MULTIDRUG EFFLUX PROTEIN, MEMBRANE PROTEIN, TRANSPORT PROTEIN
4dxl:A (LEU245) to (PRO301) CRYSTAL STRUCTURE OF ISPE (4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE) FROM MYCOBACTERIUM ABSCESSUS, BOUND TO CMP AND ATP | SSGCID, NIH, NIAID, SBRI, EMERALD BIOSTRUCTURES, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
3pm9:D (VAL362) to (SER431) CRYSTAL STRUCTURE OF A PUTATIVE DEHYDROGENASE (RPA1076) FROM RHODOPSEUDOMONAS PALUSTRIS CGA009 AT 2.57 A RESOLUTION | PUTATIVE D-2-HYDROXYGLUTARATE DEHYDROGENASE, PUTATIVE D-LACTATE DEHYDROGENASE, FAD-BINDING/TRANSPORTER-ASSOCIATED DOMAIN-LIKE FOLD, FERREDOXIN-LIKE FOLD, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, OXIDOREDUCTASE
4e2f:D (ILE25) to (ASN88) CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE K164E/E239K MUTANT IN AN INTERMEDIATE STATE | TRANSFERASE, COOPERATIVITY, ALLOSTERIC TRANSITION, INTERMEDIATE, TRANSFERASE-PROTEIN BINDING COMPLEX
4e2f:B (ILE25) to (ASN88) CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE K164E/E239K MUTANT IN AN INTERMEDIATE STATE | TRANSFERASE, COOPERATIVITY, ALLOSTERIC TRANSITION, INTERMEDIATE, TRANSFERASE-PROTEIN BINDING COMPLEX
4e2f:J (ILE25) to (ASN88) CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE K164E/E239K MUTANT IN AN INTERMEDIATE STATE | TRANSFERASE, COOPERATIVITY, ALLOSTERIC TRANSITION, INTERMEDIATE, TRANSFERASE-PROTEIN BINDING COMPLEX
4e2f:L (ILE25) to (ASN88) CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE K164E/E239K MUTANT IN AN INTERMEDIATE STATE | TRANSFERASE, COOPERATIVITY, ALLOSTERIC TRANSITION, INTERMEDIATE, TRANSFERASE-PROTEIN BINDING COMPLEX
4e2f:H (ILE25) to (ASN88) CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE K164E/E239K MUTANT IN AN INTERMEDIATE STATE | TRANSFERASE, COOPERATIVITY, ALLOSTERIC TRANSITION, INTERMEDIATE, TRANSFERASE-PROTEIN BINDING COMPLEX
4e2f:F (ILE25) to (ASN88) CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE K164E/E239K MUTANT IN AN INTERMEDIATE STATE | TRANSFERASE, COOPERATIVITY, ALLOSTERIC TRANSITION, INTERMEDIATE, TRANSFERASE-PROTEIN BINDING COMPLEX
4e6a:A (SER61) to (GLU160) P38A-PIA23 COMPLEX | MAP KINASE, P38, SIGNAL TRANSDUCTION, ALTERNATIVE ACTIVATION MODES, LIPID BINDING SITE, PIA, PERIFOSINE, KINASE FOLD, KINASE, SUBSTRATES, PHOSPHORYLATION, TRANSFERASE
4e76:A (THR286) to (TYR358) APO CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH BETA HAIRPIN LOOP DELETION | RDRP, LOOPLESS DELTA8, FLAVIVIRIDAE, HEPATITIS C VIRUS, VIRAL PROTEIN, TRANSFERASE
4usi:B (LEU30) to (GLU116) NITROGEN REGULATORY PROTEIN PII FROM CHLAMYDOMONAS REINHARDTII IN COMPLEX WITH MGATP AND 2-OXOGLUTARATE | SIGNALING PROTEIN
4usk:A (ALA278) to (ASN331) UNRAVELLING THE B. PSEUDOMALLEI HEPTOKINASE WCBL: FROM STRUCTURE TO DRUG DISCOVERY. | TRANSFERASE, CAPSULAR POLYSACCHARIDE, HEPTOPYRANOSE
4usk:B (ALA278) to (ASN331) UNRAVELLING THE B. PSEUDOMALLEI HEPTOKINASE WCBL: FROM STRUCTURE TO DRUG DISCOVERY. | TRANSFERASE, CAPSULAR POLYSACCHARIDE, HEPTOPYRANOSE
3pr4:A (LYS78) to (SER145) DPO4 Y12A MUTANT INCORPORATING DADP OPPOSITE TEMPLATE DT | DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
3pr5:B (LYS78) to (SER145) DPO4 Y12A MUTANT INCORPORATING ADP OPPOSITE TEMPLATE DT | DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
4ust:A (ARG66) to (GLY150) CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE WITH PYROPHOSPHATE RESULTING FROM SOAKING WITH GTP AND MAGNESIUM | LYASE, REACTION PRODUCT, PYROPHOSPHATE
4usu:A (ARG66) to (GLY150) CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE IN COMPLEX WITH ALPHA,BETA-METHYLENEADENOSINE-5'-TRIPHOSPHATE | LYASE, APCPP
4usv:A (ARG66) to (GLY150) CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE WITH PYROPHOSPHATE RESULTING FROM SOAKING WITH ATP AND CALCIUM | LYASE, REACTION PRODUCT
4usw:A (ARG66) to (GLY150) CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE WITH ATP | LYASE, ATP SUBSTRATE
4ut4:B (ALA278) to (ASN331) BURKHOLDERIA PSEUDOMALLEI HEPTOKINASE WCBL, D-MANNOSE COMPLEX. | TRANSFERASE, CAPSULAR POLYSACCHARIDE, DRUG DISCOVERY, HEPTOPYRANOSE
4utg:B (ASN277) to (ASN331) BURKHOLDERIA PSEUDOMALLEI HEPTOKINASE WCBL,AMPPNP (ATP ANALOGUE) COMPLEX. | TRANSFERASE, CAPSULAR POLYSACCHARIDE, DRUG DISCOVERY, HEPTOPYRANOSE
4e7x:C (ASP59) to (ALA138) STRUCTURAL BASIS FOR THE ACTIVITY OF A CYTOPLASMIC RNA TERMINAL U- TRANSFERASE | BETA POLYMERASE-LIKE NUCLEOTIDYL TRANSFERASE, TERMINAL URIDINE TRANSFERASE, UTP, RNA, CYTOPLASMIC, TRANSFERASE
4e80:A (ASP59) to (ALA138) STRUCTURAL BASIS FOR THE ACTIVITY OF A CYTOPLASMIC RNA TERMINAL U- TRANSFERASE | BETA POLYMERASE-LIKE NUCLEOTIDYL TRANSFERASE, TERMINAL URIDINE TRANSFERASE, UTP, RNA, CYTOPLASMIC, TRANSFERASE
4eaw:A (THR286) to (TYR358) HCV NS5B IN COMPLEX WITH IDX375 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eaw:B (THR286) to (TYR358) HCV NS5B IN COMPLEX WITH IDX375 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ed4:A (LEU245) to (PRO301) CRYSTAL STRUCTURE OF ISPE (4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE) FROM MYCOBACTERIUM ABCESSUS, BOUND TO ATP | SSGCID, NIH, NIAID, SBRI, EMERALD BIOSTRUCTURES, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
4eh4:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH NP-F3 AND RL87 | MAP KINASE INSERT, KINASE-LIGAND COMPLEX, NP-FRAGMENT, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3pvx:A (GLU79) to (SER145) BINARY COMPLEX OF AFLATOXIN B1 ADDUCT MODIFIED DNA (AFB1-FAPY) WITH DNA POLYMERASE IV | DNA POLYMERASE, DNA ADDUCT, TRANSFERASE-DNA COMPLEX
3pw0:A (GLU79) to (SER145) TERNARY COMPLEX OF AFLATOXIN B1 ADDUCT MODIFIED DNA (AFB1-FAPY) WITH DNA POLYMERASE IV AND INCOMING DATP | TERNARY COMPLEX OF DPO4-DNA-DATP, DNA POLYMERASE, DNA ADDUCT, TRANSFERASE-DNA COMPLEX
3pw4:A (GLU80) to (SER146) TERNARY COMPLEX OF AFLATOXIN B1 ADDUCT MODIFIED DNA (AFB1-N7-GUA) WITH DNA POLYMERASE IV AND INCOMING DATP | TERNARY COMPLEX OF DPO4-DNA-DATP, DNA POLYMERASE, DNA ADDUCT, TRANSFERASE-DNA COMPLEX
3pw5:A (LYS79) to (SER146) TERNARY COMPLEX OF AFLATOXIN B1 ADDUCT MODIFIED DNA (AFB1-N7-GUA) WITH DNA POLYMERASE IV AND INCOMING DTTP | TERNARY COMPLEX OF DPO4-DNA-DTTP, DNA POLYMERASE, DNA ADDUCT, TRANSFERASE-DNA COMPLEX
3pye:A (ALA236) to (PRO293) MYCOBACTERIUM TUBERCULOSIS 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE (ISPE) IN COMPLEX WITH CDPME | KINASE, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, TRANSFERASE
3pyf:A (ALA236) to (PRO293) MYCOBACTERIUM TUBERCULOSIS 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE (ISPE) IN COMPLEX WITH AMP-PNP | KINASE, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, TRANSFERASE
4emd:A (LEU245) to (PRO301) CRYSTAL STRUCTURE OF ISPE (4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE) FROM MYCOBACTERIUM ABCESSUS, BOUND TO CMP AND SO4 | SSGCID, NIH, NIAID, SBRI, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
3q0z:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3q0z:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eo6:A (THR286) to (TYR358) HCV NS5B POLYMERASE INHIBITORS: TRI-SUBSTITUTED ACYLHYDRAZINES AS TERTIARY AMIDE BIOISOSTERES | HCV, NS5B, RNA, RNA POLYMERASE, POLYMERASE INHIBITOR, THUMB SITE 2 INHIBITOR, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eo6:B (THR286) to (TYR358) HCV NS5B POLYMERASE INHIBITORS: TRI-SUBSTITUTED ACYLHYDRAZINES AS TERTIARY AMIDE BIOISOSTERES | HCV, NS5B, RNA, RNA POLYMERASE, POLYMERASE INHIBITOR, THUMB SITE 2 INHIBITOR, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5iv3:A (ARG66) to (GLY150) CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE IN COMPLEX WITH ALPHA,BETA-METHYLENEADENOSINE-5'-TRIPHOSPHATE AND THE ALLOSTERIC INHIBITOR LRE1 | HUMAN SOLUBLE ADENYLYL CYCLASE HSAC COMPLEX ALPHA, BETA- METHYLENEADENOSINE-5'-TRIPHOSPHATE, ALLOSTERIC INHIBITOR LRE1, LYASE
4eu0:A (GLY355) to (GLU428) CRYSTAL STRUCTURE OF PELD 158-CT FROM PSEUDOMONAS AERUGINOSA PAO1 | C-DI-GMP, SIGNALING PROTEIN
4f25:A (ASN112) to (ARG172) CRYSTAL STRUCTURE OF THE SECOND RRM DOMAIN OF HUMAN PABPC1 AT PH 6.0 | RRM FOLD, TRANSLATION INITIATION, RNA-BINDING, EIF4G-BINDING, TRANSLATION
3qfh:A (THR40) to (ALA88) 2.05 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF EPIDERMIN LEADER PEPTIDE PROCESSING SERINE PROTEASE (EPIP) FROM STAPHYLOCOCCUS AUREUS. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, ALPHA AND BETA PROTEINS (A/B), SUBTILISIN-LIKE, ROSSMANN FOLD, SERINE-TYPE ENDOPEPTIDASE ACTIVITY, HYDROLASE
3qfh:B (THR40) to (ALA88) 2.05 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF EPIDERMIN LEADER PEPTIDE PROCESSING SERINE PROTEASE (EPIP) FROM STAPHYLOCOCCUS AUREUS. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, ALPHA AND BETA PROTEINS (A/B), SUBTILISIN-LIKE, ROSSMANN FOLD, SERINE-TYPE ENDOPEPTIDASE ACTIVITY, HYDROLASE
3qfh:C (THR40) to (ALA88) 2.05 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF EPIDERMIN LEADER PEPTIDE PROCESSING SERINE PROTEASE (EPIP) FROM STAPHYLOCOCCUS AUREUS. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, ALPHA AND BETA PROTEINS (A/B), SUBTILISIN-LIKE, ROSSMANN FOLD, SERINE-TYPE ENDOPEPTIDASE ACTIVITY, HYDROLASE
3qfh:D (THR40) to (ALA88) 2.05 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF EPIDERMIN LEADER PEPTIDE PROCESSING SERINE PROTEASE (EPIP) FROM STAPHYLOCOCCUS AUREUS. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, ALPHA AND BETA PROTEINS (A/B), SUBTILISIN-LIKE, ROSSMANN FOLD, SERINE-TYPE ENDOPEPTIDASE ACTIVITY, HYDROLASE
3qfh:F (ASN39) to (ALA88) 2.05 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF EPIDERMIN LEADER PEPTIDE PROCESSING SERINE PROTEASE (EPIP) FROM STAPHYLOCOCCUS AUREUS. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, ALPHA AND BETA PROTEINS (A/B), SUBTILISIN-LIKE, ROSSMANN FOLD, SERINE-TYPE ENDOPEPTIDASE ACTIVITY, HYDROLASE
3qfh:G (THR40) to (ALA88) 2.05 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF EPIDERMIN LEADER PEPTIDE PROCESSING SERINE PROTEASE (EPIP) FROM STAPHYLOCOCCUS AUREUS. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, ALPHA AND BETA PROTEINS (A/B), SUBTILISIN-LIKE, ROSSMANN FOLD, SERINE-TYPE ENDOPEPTIDASE ACTIVITY, HYDROLASE
3qfh:H (THR40) to (ALA88) 2.05 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF EPIDERMIN LEADER PEPTIDE PROCESSING SERINE PROTEASE (EPIP) FROM STAPHYLOCOCCUS AUREUS. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, ALPHA AND BETA PROTEINS (A/B), SUBTILISIN-LIKE, ROSSMANN FOLD, SERINE-TYPE ENDOPEPTIDASE ACTIVITY, HYDROLASE
3qfq:A (ASP350) to (GLY401) ASYMMETRIC ASSEMBLY OF MERKEL CELL POLYOMAVIRUS LARGE T-ANTIGEN ORIGIN BINDING DOMAINS AT THE VIRAL ORIGIN | ORIGIN BINDING DOMAIN, PROTEIN-DNA COMPLEX, REPLICATION, DNA BINDING PROTEIN-DNA COMPLEX
3qfq:B (ASP350) to (LYS400) ASYMMETRIC ASSEMBLY OF MERKEL CELL POLYOMAVIRUS LARGE T-ANTIGEN ORIGIN BINDING DOMAINS AT THE VIRAL ORIGIN | ORIGIN BINDING DOMAIN, PROTEIN-DNA COMPLEX, REPLICATION, DNA BINDING PROTEIN-DNA COMPLEX
3qgd:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-1-[(4-ETHYLPHENYL)SULFONYL]- N-(4-METHOXYBENZYL)PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qgd:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-1-[(4-ETHYLPHENYL)SULFONYL]- N-(4-METHOXYBENZYL)PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qge:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qge:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qgf:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(6-CHLOROPYRIDAZIN-3-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qgf:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(6-CHLOROPYRIDAZIN-3-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4f4x:A (LYS78) to (ALA146) Y-FAMILY DNA POLYMERASE CHIMERA DBH-DPO4-DPO4 #2 | Y-FAMILY POLYMERASE, TRANSFERASE-DNA COMPLEX
3qgg:A (SER288) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND N-CYCLOPROPYL-6-[(3R)-3-{[4-(TRIFLUOROMETHOXY)BENZYL]CARBAMOYL}- 4-{[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZIN-1-YL]PYRIDAZINE-3- CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qgg:B (SER288) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND N-CYCLOPROPYL-6-[(3R)-3-{[4-(TRIFLUOROMETHOXY)BENZYL]CARBAMOYL}- 4-{[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZIN-1-YL]PYRIDAZINE-3- CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qgh:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 1A COMPLEX WITH N-CYCLOPROPYL-6-[(3R)-3-{[4- (TRIFLUOROMETHOXY)BENZYL]CARBAMOYL}-4-{[4-(TRIFLUOROMETHOXY) PHENYL]SULFONYL}PIPERAZIN-1-YL]PYRIDAZINE-3-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5j2n:A (SER156) to (GLU224) HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DNA THAT HAS INCORPORATED EFDA-MP AT THE P-(POST-TRANSLOCATION) SITE AND DTMP AT THE N-(PRE- TRANSLOCATION) SITE | HIV-1, REVERSE TRANSCRIPTASE, RT, DNA, DOUBLE STRANDED DNA, DSDNA, EFDA, 4'-ETHYNYL-2-FLUORO-2'-DEOXYADENOSINE, EFDA-MONOPHOSPHATE, EFDA-MP, INHIBITORS, NRTI, TDRTI, TRANSLOCATION DEFECTIVE, PRE- TRANSLOCATION, N SITE, TRANSFERASE-DNA COMPLEX
4f4z:B (LYS78) to (SER145) Y-FAMILY DNA POLYMERASE CHIMERA DPO4-DPO4-DBH | Y-FAMILY POLYMERASE, TRANSFERASE-DNA COMPLEX
4f4z:A (GLU79) to (SER145) Y-FAMILY DNA POLYMERASE CHIMERA DPO4-DPO4-DBH | Y-FAMILY POLYMERASE, TRANSFERASE-DNA COMPLEX
3qgi:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 1A COMPLEX WITH N-[(2S)-BUTAN-2-YL]-6-[(3R)-3- {[4-(TRIFLUOROMETHOXY)BENZYL]CARBAMOYL}-4-{[4-(TRIFLUOROMETHOXY) PHENYL]SULFONYL}PIPERAZIN-1-YL]PYRIDAZINE-3-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5j2p:A (TRP153) to (GLU224) HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DNA THAT HAS INCORPORATED EFDA-MP AT THE P-(POST-TRANSLOCATION) SITE AND A SECOND EFDA-MP AT THE N-(PRE-TRANSLOCATION) SITE | HIV-1, REVERSE TRANSCRIPTASE, RT, DNA, DOUBLE STRANDED DNA, DSDNA, EFDA, 4'-ETHYNYL-2-FLUORO-2'-DEOXYADENOSINE, EFDA-MONOPHOSPHATE, EFDA-MP, INHIBITORS, NRTI, TDRTI, TRANSLOCATION DEFECTIVE, P SITE, N SITE, PRE-TRANSLOCATION, POST-TRANSLOCATION, TRANSFERASE-DNA COMPLEX
3qid:A (ASP331) to (GLN386) CRYSTAL STRUCTURES AND FUNCTIONAL ANALYSIS OF MURINE NOROVIRUS RNA- DEPENDENT RNA POLYMERASE | RNA POLYMERASE, VIRAL REPLICATION ENZYME, TRANSFERASE
3qid:B (ASP331) to (GLN386) CRYSTAL STRUCTURES AND FUNCTIONAL ANALYSIS OF MURINE NOROVIRUS RNA- DEPENDENT RNA POLYMERASE | RNA POLYMERASE, VIRAL REPLICATION ENZYME, TRANSFERASE
3qid:C (ASP331) to (GLN386) CRYSTAL STRUCTURES AND FUNCTIONAL ANALYSIS OF MURINE NOROVIRUS RNA- DEPENDENT RNA POLYMERASE | RNA POLYMERASE, VIRAL REPLICATION ENZYME, TRANSFERASE
4v02:A (ILE60) to (ASP121) MINC:MIND CELL DIVISION PROTEIN COMPLEX, AQUIFEX AEOLICUS | CELL CYCLE, BACTERIAL CELL DIVISION, FTSZ, MIN SYSTEM
4v02:B (ASP59) to (ASP121) MINC:MIND CELL DIVISION PROTEIN COMPLEX, AQUIFEX AEOLICUS | CELL CYCLE, BACTERIAL CELL DIVISION, FTSZ, MIN SYSTEM
4fbt:A (LYS78) to (SER145) DPO4 POST-INSERTION COMPLEX WITH THE N-(DEOXYGUANOSIN-8-YL)-1- AMINOPYRENE LESION | DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
4fbu:A (LYS78) to (SER145) DPO4 POLYMERASE PRE-INSERTION BINARY COMPLEX WITH THE N- (DEOXYGUANOSIN-8-YL)-1-AMINOPYRENE LESION | DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
4fbu:B (LYS78) to (SER145) DPO4 POLYMERASE PRE-INSERTION BINARY COMPLEX WITH THE N- (DEOXYGUANOSIN-8-YL)-1-AMINOPYRENE LESION | DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
3qo5:A (ASN214) to (SER262) CRYSTAL STRUCTURE OF THE SERYL-TRNA SYNTHETASE FROM CANDIDA ALBICANS | GENETIC CODE AMBIGUITY, TRNA, CLASS-II AMINOACYL-TRNA SYNTHETASE FAMILY, TYPE-1 SERYL-TRNA SYNTHETASE SUBFAMILY, TRNA AMINOACYLATION, SERINE, LIGASE
3qo8:A (ASN214) to (SER262) CRYSTAL STRUCTURE OF SERYL-TRNA SYNTHETASE FROM CANDIDA ALBICANS | CLASS-II AMINOACYL-TRNA SYNTHETASE FAMILY, TYPE-1 SERYL-TRNA SYNTHETASE SUBFAMILY, AMINOACYL-TRNA SYNTHETASE, SERINE, TRNA, LIGASE
3qt6:A (GLN259) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH INHIBITOR DPGP | GHMP KINASE FAMILY, LYASE-LYASE INHIBITOR COMPLEX
3qt6:B (GLU260) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH INHIBITOR DPGP | GHMP KINASE FAMILY, LYASE-LYASE INHIBITOR COMPLEX
3qt7:A (GLU260) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH INHIBITOR 6-FMVAPP | GHMP KINASE FAMILY, LYASE-LYASE INHIBITOR COMPLEX
3qt8:A (GLN259) to (ASP317) CRYSTAL STRUCTURE OF MUTANT S192A STAPHYLOCOCCUS EPIDERMIDIS MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH INHIBITOR 6- FMVAPP | GHMP KINASE FAMILY, LYASE-LYASE INHIBITOR COMPLEX
4fn5:A (MET631) to (MET685) ELONGATION FACTOR G 1 (PSEUDOMONAS AERUGINOSA) IN COMPLEX WITH ARGYRIN B | ELONGATION FACTOR, TRANSLATION, TRANSLATION-ANTIBIOTIC COMPLEX
3rb3:A (LYS78) to (SER145) DPO4 EXTENSION TERNARY COMPLEX WITH 3'-TERMINAL PRIMER A BASE OPPOSITE THE 1-METHYLGUANINE (M1G) LESION | DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, MAGNESIUM, METAL-BINDING, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX, LESION BYPASS, DNA POLYMERASE, Y-FAMILY POLYMERASE, DNTP-BINDING, 1- METHYLGUANINE
4fyx:B (ILE25) to (ASN88) E. COLI ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH DCTP, UTP, AND MG2+ | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, ALLOSTERY, TRANSFERASE
4fyx:D (ILE25) to (ASN88) E. COLI ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH DCTP, UTP, AND MG2+ | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, ALLOSTERY, TRANSFERASE
4fyy:B (ILE25) to (ASN88) E. COLI ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH CTP, UTP, AND MG2+ | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, ALLOSTERY, TRANSFERASE
4fyy:D (ILE25) to (ASN88) E. COLI ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH CTP, UTP, AND MG2+ | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, ALLOSTERY, TRANSFERASE
4gc6:A (GLU79) to (SER145) CRYSTAL STRUCTURE OF DPO4 IN COMPLEX WITH N-MC-DAMP OPPOSITE DT | DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
4gc7:A (GLU79) to (SER145) CRYSTAL STRUCTURE OF DPO4 IN COMPLEX WITH S-MC-DADP OPPOSITE DT | DNA POLYMERASE, TRANSFERASE-RNA COMPLEX
4gc7:B (GLU79) to (SER145) CRYSTAL STRUCTURE OF DPO4 IN COMPLEX WITH S-MC-DADP OPPOSITE DT | DNA POLYMERASE, TRANSFERASE-RNA COMPLEX
4geo:A (SER61) to (GLU160) P38A MAP KINASE DEF-POCKET PENTA MUTANT (M194A, L195A, H228A, I229A, Y258A) | DOCKING SITE, SUBSTRATE SELECTIVITY, SER/THR KINASE, PHOSPHORYLATION, TRANSFERASE
5ktq:A (LEU768) to (ILE823) LARGE FRAGMENT OF TAQ DNA POLYMERASE BOUND TO DCTP | LARGE FRAGEMENT OF TAQ DNA POLYMERASE I, TRANSFERASE
5kz5:R (MET315) to (SER379) ARCHITECTURE OF THE HUMAN MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY MACHINERY: THE COMPLEX FORMED BY THE IRON DONOR, THE SULFUR DONOR, AND THE SCAFFOLD | FRATAXIN, IRON-SULFUR PROTEIN, MITOCHONDRIA, PROTEIN COMPLEX, TRANSFERASE-OXIDOREDUCTASE COMPLEX
5l3j:A (GLU185) to (ASP248) ESCHERICHIA COLI DNA GYRASE B IN COMPLEX WITH BENZOTHIAZOLE-BASED INHIBITOR | GYRASE B, INHIBITOR, COMPLEX, GYRB, PROTEROS BIOSTRUCTURES, ISOMERASE, PROTEROS BIOSTRUCTURES GMBH
5ldf:A (GLN189) to (PHE255) MALTOSE BINDING PROTEIN GENETICALLY FUSED TO DODECAMERIC GLUTAMINE SYNTHETASE | FUSION PROTEIN, CHIMERA, DODECAMER, SYMMETRIZED CONSTRUCT, LIGASE
5ldf:B (GLN189) to (PHE255) MALTOSE BINDING PROTEIN GENETICALLY FUSED TO DODECAMERIC GLUTAMINE SYNTHETASE | FUSION PROTEIN, CHIMERA, DODECAMER, SYMMETRIZED CONSTRUCT, LIGASE
5ldf:C (GLN189) to (PHE255) MALTOSE BINDING PROTEIN GENETICALLY FUSED TO DODECAMERIC GLUTAMINE SYNTHETASE | FUSION PROTEIN, CHIMERA, DODECAMER, SYMMETRIZED CONSTRUCT, LIGASE
5ldf:D (GLN189) to (PHE255) MALTOSE BINDING PROTEIN GENETICALLY FUSED TO DODECAMERIC GLUTAMINE SYNTHETASE | FUSION PROTEIN, CHIMERA, DODECAMER, SYMMETRIZED CONSTRUCT, LIGASE
5ldf:E (GLN189) to (PHE255) MALTOSE BINDING PROTEIN GENETICALLY FUSED TO DODECAMERIC GLUTAMINE SYNTHETASE | FUSION PROTEIN, CHIMERA, DODECAMER, SYMMETRIZED CONSTRUCT, LIGASE
5ldf:F (GLN189) to (PHE255) MALTOSE BINDING PROTEIN GENETICALLY FUSED TO DODECAMERIC GLUTAMINE SYNTHETASE | FUSION PROTEIN, CHIMERA, DODECAMER, SYMMETRIZED CONSTRUCT, LIGASE
5ldf:G (GLN189) to (PHE255) MALTOSE BINDING PROTEIN GENETICALLY FUSED TO DODECAMERIC GLUTAMINE SYNTHETASE | FUSION PROTEIN, CHIMERA, DODECAMER, SYMMETRIZED CONSTRUCT, LIGASE
5ldf:H (GLN189) to (PHE255) MALTOSE BINDING PROTEIN GENETICALLY FUSED TO DODECAMERIC GLUTAMINE SYNTHETASE | FUSION PROTEIN, CHIMERA, DODECAMER, SYMMETRIZED CONSTRUCT, LIGASE
5ldf:I (GLN189) to (PHE255) MALTOSE BINDING PROTEIN GENETICALLY FUSED TO DODECAMERIC GLUTAMINE SYNTHETASE | FUSION PROTEIN, CHIMERA, DODECAMER, SYMMETRIZED CONSTRUCT, LIGASE
5ldf:J (GLN189) to (PHE255) MALTOSE BINDING PROTEIN GENETICALLY FUSED TO DODECAMERIC GLUTAMINE SYNTHETASE | FUSION PROTEIN, CHIMERA, DODECAMER, SYMMETRIZED CONSTRUCT, LIGASE
5ldf:K (GLN189) to (PHE255) MALTOSE BINDING PROTEIN GENETICALLY FUSED TO DODECAMERIC GLUTAMINE SYNTHETASE | FUSION PROTEIN, CHIMERA, DODECAMER, SYMMETRIZED CONSTRUCT, LIGASE
5ldf:L (GLN189) to (PHE255) MALTOSE BINDING PROTEIN GENETICALLY FUSED TO DODECAMERIC GLUTAMINE SYNTHETASE | FUSION PROTEIN, CHIMERA, DODECAMER, SYMMETRIZED CONSTRUCT, LIGASE
5trh:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-[(BENZENECARBONYL)AMINO]-3-[(4- CHLOROPHENYL)METHOXY]BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trh:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-[(BENZENECARBONYL)AMINO]-3-[(4- CHLOROPHENYL)METHOXY]BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trk:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA- DEPENDENT RNA POLYMERASE IN COMPLEX WITH N-{3-[(BENZENECARBONYL)AMINO]-4-[(4- CHLOROPHENYL)METHOXY]BENZENE-1-CARBONYL}GLYCINE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trk:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA- DEPENDENT RNA POLYMERASE IN COMPLEX WITH N-{3-[(BENZENECARBONYL)AMINO]-4-[(4- CHLOROPHENYL)METHOXY]BENZENE-1-CARBONYL}GLYCINE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
6at1:B (ILE25) to (ASN88) STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION | TRANSFERASE (CARBAMOYL-P,ASPARTATE)
7at1:B (ILE25) to (ASN88) CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H | TRANSFERASE (CARBAMOYL-P,ASPARTATE)
4wij:A (THR309) to (PHE366) HUMAN SPLICING FACTOR, CONSTRUCT 1 | RRM, TRANSCRIPTION
2baj:A (SER61) to (GLU160) P38ALPHA BOUND TO PYRAZOLOUREA | MITOGEN ACTIVATED PROTEIN KINASE, TRANSFERASE
2p9c:B (VAL350) to (TYR410) CRYSTAL STRUCTURE OF SERINE BOUND G336V MUTANT OF E.COLI PHOSPHOGLYCERATE DEHYDROGENASE | OXIDOREDUCTASE, PHOSPHOGLYCERATE DEHYDROGENASE
2pc6:C (ALA15) to (ASP75) CRYSTAL STRUCTURE OF PUTATIVE ACETOLACTATE SYNTHASE- SMALL SUBUNIT FROM NITROSOMONAS EUROPAEA | ACETOLACTATE SYNTHASE, REGULATORY SUBUNIT, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, LYASE
2pc6:D (ALA13) to (ASP75) CRYSTAL STRUCTURE OF PUTATIVE ACETOLACTATE SYNTHASE- SMALL SUBUNIT FROM NITROSOMONAS EUROPAEA | ACETOLACTATE SYNTHASE, REGULATORY SUBUNIT, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, LYASE
3s6e:B (TRP442) to (TYR505) CRYSTAL STRUCTURE OF A RNA BINDING MOTIF PROTEIN 39 (RBM39) FROM MUS MUSCULUS AT 0.95 A RESOLUTION | FERREDOXIN-LIKE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, RNA BINDING PROTEIN
2bqr:A (GLU79) to (SER145) DNA ADDUCT BYPASS POLYMERIZATION BY SULFOLOBUS SOLFATARICUS DPO4. ANALYSIS AND CRYSTAL STRUCTURES OF MULTIPLE BASE- PAIR SUBSTITUTION AND FRAMESHIFT PRODUCTS WITH THE ADDUCT 1,N2-ETHENOGUANINE | P2 DNA POLYMERASE IV, 1N2-ETHENOGUANINE ADDUCT, TRANSLESION DNA POLYMERASE, DATP, NUCLEOTIDYLTRANSFERASE, TRANSFERASE
2brk:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH AN ALLOSTERIC INHIBITOR (COMPOUND 1) | TRANSFERASE, HEPATITIS C VIRUS, HCV, NS5B, POLYMERASE, RNA-DEPENDENT RNA- POLYMERASE, ALLOSTERIC INHIBITOR, ATP-BINDING
2brl:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH AN ALLOSTERIC INHIBITOR (COMPOUND 2) | TRANSFERASE, HEPATITIS C VIRUS, HCV, NS5B, POLYMERASE, RNA-DEPENDENT RNA- POLYMERASE, ALLOSTERIC INHIBITOR, NUCLEOTIDYLTRANSFERASE
4hxz:A (LYS181) to (ASN243) PYRROLOPYRIMIDINE INHIBITORS OF DNA GYRASE B AND TOPOISOMERASE IV, PART I: STRUCTURE GUIDED DISCOVERY AND OPTIMIZATION OF DUAL TARGETING AGENTS WITH POTENT, BROAD-SPECTRUM ENZYMATIC ACTIVITY. | ATP-BINDING, NUCLEOTIDE-BINDING, TOPOISOMERASE, ATP-BINDING DOMAIN, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
3sfg:A (ASP331) to (GLN386) CRYSTAL STRUCTURE OF MURINE NOROVIRUS RNA DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2THIOURIDINE(2TU) | RIGHT HAND CONFORMATION, POLYMERASE, RNA BINDING, TRANSFERASE
3sfg:C (ASP331) to (GLN386) CRYSTAL STRUCTURE OF MURINE NOROVIRUS RNA DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2THIOURIDINE(2TU) | RIGHT HAND CONFORMATION, POLYMERASE, RNA BINDING, TRANSFERASE
1os5:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE COMPLEXED WITH A NOVEL NON-COMPETITIVE INHIBITOR. | ENZYME-INHIBITOR COMPLEX, TRANSFERASE
2cfh:A (ASP70) to (PHE150) STRUCTURE OF THE BET3-TPC6B CORE OF TRAPP | PROTEIN TRANSPORT, TRAPP COMPLEX, BET3, TPC6, VESICLE TETHERING, TRANSPORT, ER-GOLGI TRANSPORT, ENDOPLASMIC RETICULUM
2cfh:B (ASP70) to (PHE150) STRUCTURE OF THE BET3-TPC6B CORE OF TRAPP | PROTEIN TRANSPORT, TRAPP COMPLEX, BET3, TPC6, VESICLE TETHERING, TRANSPORT, ER-GOLGI TRANSPORT, ENDOPLASMIC RETICULUM
3t01:A (VAL268) to (GLY330) CRYSTAL STRUCTURE OF PHOSPHONOACETATE HYDROLASE FROM SINORHIZOBIUM MELILOTI 1021 IN COMPLEX WITH PHOSPHONOFORMATE | ALKALINE PHOSPHATASE SUPERFAMILY, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1p9n:A (SER52) to (GLU103) CRYSTAL STRUCTURE OF ESCHERICHIA COLI MOBB. | CRYSTAL STRUCTURE, MOLYBDOPTERIN COFACTOR BIOSYNTHESIS, MOBB, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, STRUCTURAL GENOMICS, BIOSYNTHETIC PROTEIN
1p9n:B (TYR53) to (GLY104) CRYSTAL STRUCTURE OF ESCHERICHIA COLI MOBB. | CRYSTAL STRUCTURE, MOLYBDOPTERIN COFACTOR BIOSYNTHESIS, MOBB, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, STRUCTURAL GENOMICS, BIOSYNTHETIC PROTEIN
4ir1:F (ASP77) to (PRO144) POLYMERASE-DNA COMPLEX | DNA POLYMERASE, Y-FAMILY, TRANSFERASE-DNA COMPLEX
4ir1:A (ARG75) to (ALA143) POLYMERASE-DNA COMPLEX | DNA POLYMERASE, Y-FAMILY, TRANSFERASE-DNA COMPLEX
3t41:B (THR40) to (ALA88) 1.95 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF EPIDERMIN LEADER PEPTIDE PROCESSING SERINE PROTEASE (EPIP) S393A MUTANT FROM STAPHYLOCOCCUS AUREUS | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, ALPHA AND BETA PROTEINS (A/B), SUBTILISIN-LIKE, ROSSMANN FOLD, SERINE-TYPE ENDOPEPTIDASE ACTIVITY, HYDROLASE
2d41:A (THR287) to (TYR358) X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE INHIBITOR | HEPATITIS C VIRUS, RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
2d41:B (SER288) to (TYR358) X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE INHIBITOR | HEPATITIS C VIRUS, RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
3gol:A (THR287) to (TYR358) HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR (R)- 11D | 1,5-BENZODIAZEPINE, HCV POLYMERASE, NS5B, MEDICINAL CHEMISTRY, 1B-J4, TRANSFERASE
3gol:B (THR286) to (TYR358) HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR (R)- 11D | 1,5-BENZODIAZEPINE, HCV POLYMERASE, NS5B, MEDICINAL CHEMISTRY, 1B-J4, TRANSFERASE
2r42:A (HIS312) to (GLU369) THE BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACK INHIBITION OF MEVALONATE KINASE AND ISOPRENOID METABOLISM | MEVALONATE KINASE, FARNESYL THIODIPHOSPHATE, ATP-BINDING, CHOLESTEROL BIOSYNTHESIS, CYTOPLASM, LIPID SYNTHESIS, NUCLEOTIDE-BINDING, PEROXISOME, STEROID BIOSYNTHESIS, STEROL BIOSYNTHESIS, TRANSFERASE
3gtl:B (ILE554) to (ASP618) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 13MER WITH G<>U MISMATCH | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, ZINC- FINGER, DNA DAMAGE, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
2r7r:A (LYS597) to (SER671) CRYSTAL STRUCTURE OF ROTAVIRUS SA11 VP1/RNA (UGUGACC) COMPLEX | VIRAL PROTEIN, RNA-DEPENDENT RNA POLYMERASE, SINGLE SUBUNIT POLYMERASE FOLD, FINGERS, PALM, THUMB, RIGHT HAND CONFIGURATION, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE-RNA COMPLEX
2dk2:A (PHE36) to (LEU83) SOLUTION STRUCTURE OF RRM DOMAIN IN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN R (HNRNP R) | NMR, RRM DOMAIN, HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN R, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, GENE REGULATION
2dxs:A (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE COMPLEXED WITH A TETRACYCLIC INHIBITOR | HCV, NS5B, RNA POLYMERASE, TRANSFERASE/TRANSFERASE INHIBITOR COMPLEX
2dxs:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE COMPLEXED WITH A TETRACYCLIC INHIBITOR | HCV, NS5B, RNA POLYMERASE, TRANSFERASE/TRANSFERASE INHIBITOR COMPLEX
4jl9:A (VAL49) to (ILE145) CRYSTAL STRUCTURE OF MOUSE TBK1 BOUND TO BX795 | PROTIEN KINASE, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1qlt:A (SER17) to (SER101) STRUCTURE OF THE H422A MUTANT OF THE FLAVOENZYME VANILLYL-ALCOHOL OXIDASE | OXIDOREDUCTASE, FLAVOPROTEIN, METHANOL UTILIZATION, PEROXISOME, FLAVOENZYME, OXIDASE, CATALYSIS
1qlt:B (SER17) to (SER101) STRUCTURE OF THE H422A MUTANT OF THE FLAVOENZYME VANILLYL-ALCOHOL OXIDASE | OXIDOREDUCTASE, FLAVOPROTEIN, METHANOL UTILIZATION, PEROXISOME, FLAVOENZYME, OXIDASE, CATALYSIS
4yh8:A (THR65) to (LEU138) STRUCTURE OF YEAST U2AF COMPLEX | SPLICING, RRM, ZN-FINGER, 3' SPLICE SITE
3tyq:A (VAL284) to (TYR358) SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3tyq:B (VAL284) to (TYR358) SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h5s:A (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3h5s:B (THR287) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3h5u:A (THR286) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR 1 | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3h5u:B (THR286) to (TYR358) HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR 1 | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
4ju2:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 12 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju2:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 12 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2eay:A (SER13) to (TRP93) CRYSTAL STRUCTURE OF BIOTIN PROTEIN LIGASE FROM AQUIFEX AEOLICUS | BIOTIN BIOSYNTHESIS, DIMER, X-RAY DIFFRACTION, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LIGASE
3u4o:A (THR286) to (TYR358) NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE C2 ACYL SULFONAMIDES | NUCLEOTIDYL TRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3u4o:B (THR286) to (TYR358) NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE C2 ACYL SULFONAMIDES | NUCLEOTIDYL TRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4juz:A (GLU79) to (SER145) TERNARY COMPLEX OF GAMMA-OHPDG ADDUCT MODIFIED DNA (ZERO PRIMER) WITH DNA POLYMERASE IV AND INCOMING DGTP | TERNARY COMPLEX OF DPO4-DNA-DATP, DNA POLYMERASE, DNA ADDUCT, TRANSFERASE-DNA COMPLEX
1r0c:B (ILE25) to (ARG85) PRODUCTS IN THE T STATE OF ASPARTATE TRANSCARBAMYLASE: CRYSTAL STRUCTURE OF THE PHOSPHATE AND N-CARBAMYL-L-ASPARTATE LIGATED ENZYME | ASPARTATE TRANSCARBAMYLASE, ASPARTATE CARBAMOYLTRANSFERASE, PRODUCTS, N-CARBAMYL-L-ASPARTATE(CLA), PHOSPHATE, ATCASE-PRODUCTS COMPLEX, T STATE, TRANSFERASE
1r0c:H (ILE25) to (ARG85) PRODUCTS IN THE T STATE OF ASPARTATE TRANSCARBAMYLASE: CRYSTAL STRUCTURE OF THE PHOSPHATE AND N-CARBAMYL-L-ASPARTATE LIGATED ENZYME | ASPARTATE TRANSCARBAMYLASE, ASPARTATE CARBAMOYLTRANSFERASE, PRODUCTS, N-CARBAMYL-L-ASPARTATE(CLA), PHOSPHATE, ATCASE-PRODUCTS COMPLEX, T STATE, TRANSFERASE
2uvr:A (LYS78) to (SER145) CRYSTAL STRUCTURES OF MUTANT DPO4 DNA POLYMERASES WITH 8- OXOG CONTAINING DNA TEMPLATE-PRIMER CONSTRUCTS | TRANSFERASE, DNA-DIRECTED DNA POLYMERASE, P2 DNA POLYMERASE IV, NUCLEOTIDYLTRANSFERASE, 7, MAGNESIUM, DNA DAMAGE, DNA REPAIR, DNA-BINDING, TRANSLESION DNA POLYMERASE, DNA- BINDING, METAL-BINDING, 8-DIHYDRO-8- OXODEOXYGUANOSINE, METAL- BINDING, MUTATOR PROTEIN, DNA REPLICATION
2uvw:A (LYS78) to (SER145) CRYSTAL STRUCTURES OF MUTANT DPO4 DNA POLYMERASES WITH 8- OXOG CONTAINING DNA TEMPLATE-PRIMER CONSTRUCTS | TRANSFERASE, DNA-DIRECTED DNA POLYMERASE, P2 DNA POLYMERASE IV, NUCLEOTIDYLTRANSFERASE, 7, MAGNESIUM, DNA DAMAGE, DNA REPAIR, DNA-BINDING, TRANSLESION DNA POLYMERASE, DNA- BINDING, METAL-BINDING, 8-DIHYDRO-8- OXODEOXYGUANOSINE, METAL- BINDING, MUTATOR PROTEIN, DNA REPLICATION
4jy0:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 3 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jy0:B (SER288) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 3 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1raf:D (ILE25) to (ASP87) CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | TRANSFERASE
3hl7:A (SER60) to (GLU159) CRYSTAL STRUCTURE OF HUMAN P38ALPHA COMPLEXED WITH SD-0006 | ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
1fwl:A (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE | KINASE, TRANSFERASE
1fwl:B (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE | KINASE, TRANSFERASE
1fwl:C (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE | KINASE, TRANSFERASE
1fwl:D (TYR242) to (THR291) CRYSTAL STRUCTURE OF HOMOSERINE KINASE | KINASE, TRANSFERASE
3uow:A (LYS448) to (TYR542) CRYSTAL STRUCTURE OF PF10_0123, A GMP SYNTHETASE FROM PLASMODIUM FALCIPARUM | STRUCTURAL GENOMICS CONSORTIUM, SGC, PURINE NUCLEOTIDE BIOSYNTHETIC PROCESS, LIGASE
3uow:B (LYS448) to (TYR542) CRYSTAL STRUCTURE OF PF10_0123, A GMP SYNTHETASE FROM PLASMODIUM FALCIPARUM | STRUCTURAL GENOMICS CONSORTIUM, SGC, PURINE NUCLEOTIDE BIOSYNTHETIC PROCESS, LIGASE
4kgx:B (ILE25) to (ASN88) THE R STATE STRUCTURE OF E. COLI ATCASE WITH CTP BOUND | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, COMPETING PATHWAY PRODUCT ACTIVATION, ALLOSTERY, TRANSFERASE
4kh1:B (ILE25) to (ASN88) THE R STATE STRUCTURE OF E. COLI ATCASE WITH CTP,UTP, AND MAGNESIUM BOUND | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, COMPETING PATHWAY PRODUCT ACTIVATION, ALLOSTERY, TRANSFERASE
4khr:A (THR286) to (TYR358) HCV NS5B GT1A C316Y WITH GSK5852 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DEPENDENT RNA POLYMERASE, RNA DIRECTED RNA POLYMERASE, POLYMERASE, RNS DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX
4khr:B (THR286) to (TYR358) HCV NS5B GT1A C316Y WITH GSK5852 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DEPENDENT RNA POLYMERASE, RNA DIRECTED RNA POLYMERASE, POLYMERASE, RNS DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX
1s09:A (GLN346) to (GLY394) CRYSTAL STRUCTURE OF THE Y144F MUTANT OF 7,8- DIAMINOPELARGONIC ACID SYNTHASE | AMINOTRANSFERASE, FOLD TYPE I, SUBCLASS II, HOMODIMER
1gbn:A (LEU352) to (HIS408) HUMAN ORNITHINE AMINOTRANSFERASE COMPLEXED WITH THE NEUROTOXIN GABACULINE | TRANSFERASE, ORNITHINE AMINOTRANSFERASE, UREA CYCLE, PYRIDOXAL-5'- PHOSPHATE
1gbn:C (LEU352) to (HIS408) HUMAN ORNITHINE AMINOTRANSFERASE COMPLEXED WITH THE NEUROTOXIN GABACULINE | TRANSFERASE, ORNITHINE AMINOTRANSFERASE, UREA CYCLE, PYRIDOXAL-5'- PHOSPHATE
4z7y:A (ASN260) to (SER313) DIPHOSPHOMEVALONATE DECARBOXYLASE FROM THE SULFOLOBUS SOLFATARICUS, SPACE GROUP P21 | DIPHOSPHOMEVALONATE DECARBOXYLASE, INTERSUBUNIT DISULFIDE BOND, THERMOSTABILITY, SULFOLOBUS SOLFATARICUS, LYASE
4z7y:B (ASN260) to (SER313) DIPHOSPHOMEVALONATE DECARBOXYLASE FROM THE SULFOLOBUS SOLFATARICUS, SPACE GROUP P21 | DIPHOSPHOMEVALONATE DECARBOXYLASE, INTERSUBUNIT DISULFIDE BOND, THERMOSTABILITY, SULFOLOBUS SOLFATARICUS, LYASE
4z7y:C (ASN260) to (SER313) DIPHOSPHOMEVALONATE DECARBOXYLASE FROM THE SULFOLOBUS SOLFATARICUS, SPACE GROUP P21 | DIPHOSPHOMEVALONATE DECARBOXYLASE, INTERSUBUNIT DISULFIDE BOND, THERMOSTABILITY, SULFOLOBUS SOLFATARICUS, LYASE
4z7y:D (ASN260) to (SER313) DIPHOSPHOMEVALONATE DECARBOXYLASE FROM THE SULFOLOBUS SOLFATARICUS, SPACE GROUP P21 | DIPHOSPHOMEVALONATE DECARBOXYLASE, INTERSUBUNIT DISULFIDE BOND, THERMOSTABILITY, SULFOLOBUS SOLFATARICUS, LYASE
4z7y:E (ASN260) to (SER313) DIPHOSPHOMEVALONATE DECARBOXYLASE FROM THE SULFOLOBUS SOLFATARICUS, SPACE GROUP P21 | DIPHOSPHOMEVALONATE DECARBOXYLASE, INTERSUBUNIT DISULFIDE BOND, THERMOSTABILITY, SULFOLOBUS SOLFATARICUS, LYASE
4z7y:F (ASN260) to (SER313) DIPHOSPHOMEVALONATE DECARBOXYLASE FROM THE SULFOLOBUS SOLFATARICUS, SPACE GROUP P21 | DIPHOSPHOMEVALONATE DECARBOXYLASE, INTERSUBUNIT DISULFIDE BOND, THERMOSTABILITY, SULFOLOBUS SOLFATARICUS, LYASE
3uvp:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH A BENZAMIDE SUBSTITUTED BENZOSUBERONE | PROTEIN KINASE, SELECTIVE P38 INHIBITOR, SAR, BENZOSUBERON DERIVATIVE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4zcl:B (GLN412) to (THR468) CRYSTAL STRUCTURE OF ESCHERICHIA COLI GTPASE BIPA/TYPA COMPLEXED WITH GDP | BIPA, GTPASE, NUCLEOTIDE, GTP-BINDING PROTEIN
3hv7:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH RL38 | DFG-OUT, TYPE III, RL38, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3hvo:B (THR286) to (TYR358) STRUCTURE OF THE GENOTYPE 2B HCV POLYMERASE BOUND TO A NNI | VIRAL POLYMERASE, ATP-BINDING, HYDROLASE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE
3v6j:A (LYS78) to (SER145) REPLICATION OF N2,3-ETHENOGUANINE BY DNA POLYMERASES | SULFOLOBUS SOLFATARICUS DNA POLYMERASE IV, DPO4, ETHENOGUANINE, DNA ADDUCT, DNA LESION, DNA POLYMERASE, DNA REPLICATION, LESION BYPASS, 2'-FLUORO ARABINOSE, N2,3-ETHENOGUANINE, TRANSFERASE-DNA COMPLEX
3v6j:J (GLU79) to (SER145) REPLICATION OF N2,3-ETHENOGUANINE BY DNA POLYMERASES | SULFOLOBUS SOLFATARICUS DNA POLYMERASE IV, DPO4, ETHENOGUANINE, DNA ADDUCT, DNA LESION, DNA POLYMERASE, DNA REPLICATION, LESION BYPASS, 2'-FLUORO ARABINOSE, N2,3-ETHENOGUANINE, TRANSFERASE-DNA COMPLEX
2fzk:D (ALA23) to (ASN88) THE STRUCTURE OF WILD-TYPE E. COLI ASPARTATE TRANSCARBAMOYLASE IN COMPLEX WITH NOVEL T STATE INHIBITORS AT 2.50 RESOLUTION | INHIBITORS, ALLOSTERIC TRANSITION, XRAY STRUCTURES, TRANSFERASE
1sh3:A (SER328) to (GLU383) CRYSTAL STRUCTURE OF NORWALK VIRUS POLYMERASE (MGSO4 CRYSTAL FORM) | RNA POLYMERASE, VIRAL REPLICATION ENZYME, TRANSFERASE
1sh3:B (SER328) to (GLU383) CRYSTAL STRUCTURE OF NORWALK VIRUS POLYMERASE (MGSO4 CRYSTAL FORM) | RNA POLYMERASE, VIRAL REPLICATION ENZYME, TRANSFERASE
3i5k:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF THE NS5B POLYMERASE FROM HEPATITIS C VIRUS (HCV) STRAIN JFH1 | RDRP STRUCTURE (FINGERS, PALM, THUMB DOMAINS), APOPTOSIS, ATP- BINDING, CAPSID PROTEIN, CELL MEMBRANE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3i5k:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF THE NS5B POLYMERASE FROM HEPATITIS C VIRUS (HCV) STRAIN JFH1 | RDRP STRUCTURE (FINGERS, PALM, THUMB DOMAINS), APOPTOSIS, ATP- BINDING, CAPSID PROTEIN, CELL MEMBRANE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3i5k:C (THR287) to (TYR358) CRYSTAL STRUCTURE OF THE NS5B POLYMERASE FROM HEPATITIS C VIRUS (HCV) STRAIN JFH1 | RDRP STRUCTURE (FINGERS, PALM, THUMB DOMAINS), APOPTOSIS, ATP- BINDING, CAPSID PROTEIN, CELL MEMBRANE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3i5k:D (THR287) to (TYR358) CRYSTAL STRUCTURE OF THE NS5B POLYMERASE FROM HEPATITIS C VIRUS (HCV) STRAIN JFH1 | RDRP STRUCTURE (FINGERS, PALM, THUMB DOMAINS), APOPTOSIS, ATP- BINDING, CAPSID PROTEIN, CELL MEMBRANE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
2ghm:A (SER61) to (GLU160) MUTATED MAP KINASE P38 (MUS MUSCULUS) IN COMPLEX WITH INHBITOR PG-895449 | MAP KINASE P38, TRANSFERASE
3ixq:A (TYR144) to (ILE206) STRUCTURE OF RIBOSE 5-PHOSPHATE ISOMERASE A FROM METHANOCALDOCOCCUS JANNASCHII | STRUCTURAL GENOMICS, ISOMERASE, PENTOSE PHOSPHATE PATHWAY, CARBON FIXATION, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, CARBOHYDRATE METABOLISM
2who:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR | TRANSFERASE, RNA REPLICATION, ENVELOPE PROTEIN, HEPATITIS C VIRUS, ENDOPLASMIC RETICULUM, NON NUCLEOSIDE INHIBITOR, VIRAL PROTEIN, METAL-BINDING, TRANSMEMBRANE, POLYMERASE, ATP-BINDING, GENOTYPE 1B, RNA-BINDING, RNA-DEPENDENT RNA POLYMERASE, NNI, HCV, NS5B, MEMBRANE, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, ALLOSTERIC INHIBITOR, RNA-DIRECTED RNA POLYMERASE
2who:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR | TRANSFERASE, RNA REPLICATION, ENVELOPE PROTEIN, HEPATITIS C VIRUS, ENDOPLASMIC RETICULUM, NON NUCLEOSIDE INHIBITOR, VIRAL PROTEIN, METAL-BINDING, TRANSMEMBRANE, POLYMERASE, ATP-BINDING, GENOTYPE 1B, RNA-BINDING, RNA-DEPENDENT RNA POLYMERASE, NNI, HCV, NS5B, MEMBRANE, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, ALLOSTERIC INHIBITOR, RNA-DIRECTED RNA POLYMERASE
5a9v:A (GLN412) to (PHE469) STRUCTURE OF APO BIPA | RIBOSOMAL PROTEIN, RIBOSOME, TRANSLATIONAL GTPASE FACTORS
5a9v:C (GLN412) to (PHE469) STRUCTURE OF APO BIPA | RIBOSOMAL PROTEIN, RIBOSOME, TRANSLATIONAL GTPASE FACTORS
5a9v:D (GLN412) to (PHE469) STRUCTURE OF APO BIPA | RIBOSOMAL PROTEIN, RIBOSOME, TRANSLATIONAL GTPASE FACTORS
5a9v:E (GLN412) to (PHE469) STRUCTURE OF APO BIPA | RIBOSOMAL PROTEIN, RIBOSOME, TRANSLATIONAL GTPASE FACTORS
2irx:A (MET149) to (SER216) CRYSTAL STRUCTURE OF THE POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D WITH GTP AND MANGANESE. | POLYMERASE, PRIMASE, LIGASE, NHEJ, GTP, TRANSFERASE
2xhv:A (THR287) to (TYR358) HCV-J4 NS5B POLYMERASE POINT MUTANT ORTHORHOMBIC CRYSTAL FORM | REPLICATION, TRANSCRIPTION, TRANSFERASE
2xhv:B (THR287) to (TYR358) HCV-J4 NS5B POLYMERASE POINT MUTANT ORTHORHOMBIC CRYSTAL FORM | REPLICATION, TRANSCRIPTION, TRANSFERASE
4mz4:A (SER288) to (TYR358) DISCOVERY OF AN IRREVERSIBLE HCV NS5B POLYMERASE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mz4:B (VAL284) to (TYR358) DISCOVERY OF AN IRREVERSIBLE HCV NS5B POLYMERASE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2jef:A (LYS78) to (SER145) THE MOLECULAR BASIS OF SELECTIVITY OF NUCLEOTIDE TRIPHOSPHATE INCORPORATION OPPOSITE O6-BENZYLGUANINE BY SULFOLOBUS SOLFATARICUS DNA POLYMERASE IV: STEADY-STATE AND PRE-STEADY-STATE AND X-RAY CRYSTALLOGRAPHY OF CORRECT AND INCORRECT PAIRING | DNA REPLICATION, MUTATOR PROTEIN, NUCLEOTIDYLTRANSFERASE, DNA-DIRECTED DNA POLYMERASE, DPO4, MAGNESIUM, DNA DAMAGE, DNA REPAIR, ALKYLATING AGENTS, TRANSLESION SYNTHESIS, TRANSFERASE-DNA COMPLEX, DNA-BINDING, METAL-BINDING
2xwy:A (THR287) to (TYR358) STRUCTURE OF MK-3281, A POTENT NON-NUCLEOSIDE FINGER-LOOP INHIBITOR, IN COMPLEX WITH THE HEPATITIS C VIRUS NS5B POLYMERASE | TRANSFERASE, ALLOSTERIC INHIBITOR, NUCLEOTIDYLTRANSFERASE
4ndu:A (SER15) to (GLU78) CRYSTAL STRUCTURE OF L. DECASTES ALPHA-GALACTOSYL-BINDING LECTIN IN COMPLEX WITH ALPHA-METHYLGALACTOSIDE | LECTIN, SUGAR BINDING PROTEIN
4ndu:B (SER15) to (GLU78) CRYSTAL STRUCTURE OF L. DECASTES ALPHA-GALACTOSYL-BINDING LECTIN IN COMPLEX WITH ALPHA-METHYLGALACTOSIDE | LECTIN, SUGAR BINDING PROTEIN
1wcm:B (PRO551) to (ARG617) COMPLETE 12-SUBUNIT RNA POLYMERASE II AT 3.8 ANG | DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, DNA-DEPENDENT RNA POLYMERASE, CELLULAR RNA POLYMERASE, MULTISUBUNIT CO, METAL- BINDING, NUCLEAR PROTEIN, REPEAT, TRANSCRIPTION, PHOSPHORYLATION, TRANSFERASE, ZINC, ZINC-FINGER
2y1i:A (ILE796) to (GLY869) CRYSTAL STRUCTURE OF A S-DIASTEREOMER ANALOGUE OF THE SPORE PHOTOPRODUCT IN COMPLEX WITH FRAGMENT DNA POLYMERASE I FROM BACILLUS STEAROTHERMOPHILUS | TRANSFERASE-DNA COMPLEX, DNA REPAIR, SPORE PHOTOPRODUCT, PHOTOLESION, UV LESION
1kkh:A (THR259) to (ASN312) CRYSTAL STRUCTURE OF THE METHANOCOCCUS JANNASCHII MEVALONATE KINASE | MIXED BETA SHEET, PHOSPHATE-BINDING LOOP, BETA-ALPHA-BETA, TRANSFERASE
3zs5:A (SER61) to (GLU160) STRUCTURAL BASIS FOR KINASE SELECTIVITY OF THREE CLINICAL P38ALPHA INHIBITORS | TRANSFERASE, TAK-715, SCIO-469, VX-745, SB-203580
4nrt:A (SER328) to (GLU383) HUMAN NOROVIRUS POLYMERASE BOUND TO COMPOUND 6 (SURAMIN DERIVATIVE) | RNA DEPENDENT RNA POLYMERASE, VIRAL PROTEIN-TRANSCRIPTION INHIBITOR COMPLEX
4nru:A (ASP328) to (GLN383) MURINE NOROVIRUS RNA-DEPENDENT-RNA-POLYMERASE IN COMPLEX WITH COMPOUND 6, A SURAMIN DERIVATIVE | RNA DEPENDENT RNA POLYMERASE, MURINE NOROVIRUS, VIRAL PROTEIN- TRANSCRIPTION INHIBITOR COMPLEX
4nru:B (PRO329) to (GLN383) MURINE NOROVIRUS RNA-DEPENDENT-RNA-POLYMERASE IN COMPLEX WITH COMPOUND 6, A SURAMIN DERIVATIVE | RNA DEPENDENT RNA POLYMERASE, MURINE NOROVIRUS, VIRAL PROTEIN- TRANSCRIPTION INHIBITOR COMPLEX
4nru:C (PRO329) to (GLN383) MURINE NOROVIRUS RNA-DEPENDENT-RNA-POLYMERASE IN COMPLEX WITH COMPOUND 6, A SURAMIN DERIVATIVE | RNA DEPENDENT RNA POLYMERASE, MURINE NOROVIRUS, VIRAL PROTEIN- TRANSCRIPTION INHIBITOR COMPLEX
4nru:D (ASP328) to (GLN383) MURINE NOROVIRUS RNA-DEPENDENT-RNA-POLYMERASE IN COMPLEX WITH COMPOUND 6, A SURAMIN DERIVATIVE | RNA DEPENDENT RNA POLYMERASE, MURINE NOROVIRUS, VIRAL PROTEIN- TRANSCRIPTION INHIBITOR COMPLEX
4nru:F (ASP328) to (GLN383) MURINE NOROVIRUS RNA-DEPENDENT-RNA-POLYMERASE IN COMPLEX WITH COMPOUND 6, A SURAMIN DERIVATIVE | RNA DEPENDENT RNA POLYMERASE, MURINE NOROVIRUS, VIRAL PROTEIN- TRANSCRIPTION INHIBITOR COMPLEX
2m7v:A (ALA442) to (THR512) GREEN LIGHT-ABSORBING STATE OF TEPIXJ, AN ACTIVE CYANOBACTERIOCHROME DOMAIN | PHYTOCHROME, PIXJ, BLUE/GREEN LIGHT-ABSORBING, CYANOBACTERIA, PVB, PHYCOVIOLOBILIN, SIGNALING PROTEIN
1kv2:A (SER61) to (GLU160) HUMAN P38 MAP KINASE IN COMPLEX WITH BIRB 796 | PROTEIN-INHIBITOR COMPLEX, TRANSFERASE
3zxo:B (SER487) to (MSE562) CRYSTAL STRUCTURE OF THE MUTANT ATP-BINDING DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | TRANSFERASE
3k57:A (ASP512) to (TYR594) CRYSTAL STRUCTURE OF E.COLI POL II-NORMAL DNA-DATP TERNARY COMPLEX | PROTEIN-DNA COMPLEX, DNA DAMAGE, DNA REPAIR, DNA-BINDING, DNA- DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, SOS RESPONSE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
2z67:A (SER325) to (LYS393) CRYSTAL STRUCTURE OF ARCHAEAL O-PHOSPHOSERYL-TRNA(SEC) SELENIUM TRANSFERASE (SEPSECS) | SELENOCYSTEINE BIOSYNTHESIS, SEVEN-STRANDED BETE-STRAND, PYRIDOXAL- 5'-PHOSPHATE, PROTEIN BIOSYNTHESIS, PYRIDOXAL PHOSPHATE, SELENIUM, TRANSFERASE
2z67:C (SER325) to (LYS393) CRYSTAL STRUCTURE OF ARCHAEAL O-PHOSPHOSERYL-TRNA(SEC) SELENIUM TRANSFERASE (SEPSECS) | SELENOCYSTEINE BIOSYNTHESIS, SEVEN-STRANDED BETE-STRAND, PYRIDOXAL- 5'-PHOSPHATE, PROTEIN BIOSYNTHESIS, PYRIDOXAL PHOSPHATE, SELENIUM, TRANSFERASE
4oow:A (THR286) to (TYR358) HCV NS5B POLYMERASE WITH A FRAGMENT OF QUERCETAGETIN | ENZYME, TRANSFERASE
4oow:B (THR287) to (TYR358) HCV NS5B POLYMERASE WITH A FRAGMENT OF QUERCETAGETIN | ENZYME, TRANSFERASE
1y11:A (SER234) to (SER303) MYCOBACTERIAL ADENYLYL CYCLASE RV1264, HOLOENZYME, ACTIVE STATE | ADENYLYL CYCLASE FOLD, LYASE
4oyx:A (ARG66) to (GLY150) HUMAN SOLAC COMPLEXED WITH AMPCPP | PROTEIN-SUBSTRATE ANALOGUE COMPLEX, LYASE
5d10:A (ALA311) to (GLU396) KINASE DOMAIN OF CSRC IN COMPLEX WITH RL236 | KINASE INHIBITOR, DRUG RESISTANCE, TRANSFERASE
4aep:A (SER288) to (TYR358) HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 1.8 ANGSTROM | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
5d46:A (ASN304) to (GLU382) STRUCTURAL BASIS FOR A NEW TEMPLATED ACTIVITY BY TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE: IMPLICATIONS FOR V(D)J RECOMBINATION | TDT, SYNAPSIS, DOUBLE STRAND BREAKS, TRANSFERASE
5d49:A (ARG305) to (GLU386) STRUCTURAL BASIS FOR A NEW TEMPLATED ACTIVITY BY TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE: IMPLICATIONS FOR V(D)J RECOMBINATION | TDT, SYNAPSIS, DOUBLE STRAND BREAKS, TRANSFERASE
2zze:A (THR58) to (GLU189) CRYSTAL STRUCTURE OF ALANYL-TRNA SYNTHETASE WITHOUT OLIGOMERIZATION DOMAIN IN LYSINE-METHYLATED FORM | LIGASE, HYDROLASE
2zze:B (THR58) to (GLY194) CRYSTAL STRUCTURE OF ALANYL-TRNA SYNTHETASE WITHOUT OLIGOMERIZATION DOMAIN IN LYSINE-METHYLATED FORM | LIGASE, HYDROLASE
1yba:A (GLY349) to (LEU408) THE ACTIVE FORM OF PHOSPHOGLYCERATE DEHYDROGENASE | OXIDOREDUCTASE
1yba:C (GLY349) to (LEU408) THE ACTIVE FORM OF PHOSPHOGLYCERATE DEHYDROGENASE | OXIDOREDUCTASE
5d6g:A (LEU141) to (GLU200) CRYSTAL STRUCTURE OF FRAGMENT OF RIBOSOMAL PROTEIN P0 IN COMPLEX WITH 74NT 23S RNA FROM METHANOCOCCUS JANNASCHII | ARCHAEAL PROTEINS, METHANOCOCCUS, PROTEIN STRUCTURE, RNA, RIBOSOMAL PROTEINS, RIBOSOMES, TRANSLATION
3kss:A (THR66) to (GLY130) STRUCTURE AND MECHANISM OF THE HEAVY METAL TRANSPORTER CUSA | TRANSMEMBRANE HELIX, CELL INNER MEMBRANE, CELL MEMBRANE, COPPER TRANSPORT, ION TRANSPORT, MEMBRANE, TRANSMEMBRANE, TRANSPORT, METAL TRANSPORT
1yvx:A (THR286) to (TYR358) HEPATITIS C VIRUS RNA POLYMERASE GENOTYPE 2A IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | NS5B POLYMERASE GENOTYPE 2A, NON-NUCLEOSIDE INHIBITOR, VIRAL PROTEIN
1ywr:A (SER61) to (GLU160) CRYSTAL STRUCTURE ANALYSIS OF INACTIVE P38 KINASE DOMAIN IN COMPLEX WITH A MONOCYCLIC PYRAZOLONE INHIBITOR | P38 KINASE, MONCYCLIC PYRAZOLONE, TRANSFERASE
1za1:B (ILE25) to (ASN88) STRUCTURE OF WILD-TYPE E. COLI ASPARTATE TRANSCARBAMOYLASE IN THE PRESENCE OF CTP AT 2.20 A RESOLUTION | ORDERED SUBSTRATE BINDING, COOPERATIVITY, TRANSFERASE
1za1:D (ILE25) to (ASN88) STRUCTURE OF WILD-TYPE E. COLI ASPARTATE TRANSCARBAMOYLASE IN THE PRESENCE OF CTP AT 2.20 A RESOLUTION | ORDERED SUBSTRATE BINDING, COOPERATIVITY, TRANSFERASE
1zpw:X (ASP15) to (PRO68) CRYSTAL STRUCTURE OF A HYPOTHETICAL PROTEIN TT1823 FROM THERMUS THERMOPHILUS | HYPHOTETICAL PROTEIN, THERMUS THERMOPHILUS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, UNKNOWN FUNCTION
3lv2:B (LEU356) to (ARG403) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS 7,8-DIAMINOPELARGONIC ACID SYNTHASE IN COMPLEX WITH SUBSTRATE ANALOG SINEFUNGIN | RV1568, AMINOTRANSFERASE, BIOA, 7, 8-DIAMINOPELARGONIC ACID SYNTHASE, BIOTIN BIOSYNTHESIS, PYRIDOXAL PHOSPHATE, S-ADENOSYL-L-METHIONINE, TRANSFERASE
3au6:A (LEU164) to (GLY228) DNA POLYMERASE X FROM THERMUS THERMOPHILUS HB8 TERNARY COMPLEX WITH PRIMER/TEMPLATE DNA AND DDGTP | RSGI, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, POLXC DOMAIN, PHP DOMAIN, DNA POLYMERASE, DRP LYASE, AP ENDONUCLEASE, DNA REPAIR, DNA BINDING, NUCLEOTIDE BINDING, TRANSFERASE-DNA COMPLEX
4qif:D (LEU14) to (PRO78) CRYSTAL STRUCTURE OF PDUA WITH EDGE MUTATION K26A AND PORE MUTATION S40H | BMC DOMAIN, STRUCTURAL PROTEIN, POTASSIUM, GLYCEROL, 1-2 PROPANEDIOL, TARTARIC ACID, SULFATE ION
5eho:A (ASP561) to (VAL656) RAPID DISCOVERY OF PYRIDO[3,4-D]PYRIMIDINE INHIBITORS OF MONOPOLAR SPINDLE KINASE 1 (MPS1) USING A STRUCTURE-BASED HYDRIDIZATION APPROACH | SPINDLE ASSEMBLY CHECKPOINT (SAC), ONCOLOGY TARGET PYRIDO[3, 4- D]PYRIMIDINE BASED INHIBITORS SELECTIVE AGAINST MPS1, TRANSFERASE
3mr7:C (ILE38) to (ASN98) CRYSTAL STRUCTURE OF ADENYLATE/GUANYLATE CYCLASE/HYDROLASE FROM SILICIBACTER POMEROYI | ALPHA-BETA FOLD, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, HYDROLASE
3bn4:A (PHE13) to (ALA79) CARBOXYSOME SUBUNIT, CCMK1 | HEXAMER, STRUCTURAL PROTEIN
3bn4:C (PHE13) to (ALA79) CARBOXYSOME SUBUNIT, CCMK1 | HEXAMER, STRUCTURAL PROTEIN
3bn4:E (PHE13) to (ALA79) CARBOXYSOME SUBUNIT, CCMK1 | HEXAMER, STRUCTURAL PROTEIN
3bsc:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN
3bsc:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN
3cde:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, ATP-BINDING, HOST-VIRUS INTERACTION, HYDROLASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION
3cde:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, ATP-BINDING, HOST-VIRUS INTERACTION, HYDROLASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION
4rbu:B (LEU14) to (PRO78) PDUA K26A S40Q MUTANT, FROM SALMONELLA ENTERICA SEROVAR TYPHIMURIUM LT2 | BACTERIAL MICRCOMPARTMENT SHELL PROTEIN, STRUCTURAL PROTEIN
4rbu:E (LEU14) to (PRO78) PDUA K26A S40Q MUTANT, FROM SALMONELLA ENTERICA SEROVAR TYPHIMURIUM LT2 | BACTERIAL MICRCOMPARTMENT SHELL PROTEIN, STRUCTURAL PROTEIN
4rbu:H (LEU14) to (PRO78) PDUA K26A S40Q MUTANT, FROM SALMONELLA ENTERICA SEROVAR TYPHIMURIUM LT2 | BACTERIAL MICRCOMPARTMENT SHELL PROTEIN, STRUCTURAL PROTEIN
3ces:C (MET70) to (GLN122) CRYSTAL STRUCTURE OF E.COLI MNMG (GIDA), A HIGHLY-CONSERVED TRNA MODIFYING ENZYME | TRNA MODIFICATION, FAD BINDING DOMAIN, STRUCTURAL GENOMICS, MONTREAL- KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, RNA BINDING PROTEIN
3ngt:L (LEU19) to (SER121) STRUCTURE OF LEISHMANIA NDKB COMPLEXED WITH AMP. | LMNDKB, AMP, TRANSFERASE
3cj2:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj2:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
4c9s:A (ARG22) to (LEU140) BACTERIAL CHALCONE ISOMERASE IN OPEN CONFORMATION FROM EUBACTERIUM RAMULUS AT 1.8 A RESOLUTION | ISOMERASE, FLAVONOIDS
4c9s:B (ARG22) to (LEU140) BACTERIAL CHALCONE ISOMERASE IN OPEN CONFORMATION FROM EUBACTERIUM RAMULUS AT 1.8 A RESOLUTION | ISOMERASE, FLAVONOIDS
4c9s:D (ARG22) to (LEU140) BACTERIAL CHALCONE ISOMERASE IN OPEN CONFORMATION FROM EUBACTERIUM RAMULUS AT 1.8 A RESOLUTION | ISOMERASE, FLAVONOIDS
4c9s:E (ARG22) to (LEU140) BACTERIAL CHALCONE ISOMERASE IN OPEN CONFORMATION FROM EUBACTERIUM RAMULUS AT 1.8 A RESOLUTION | ISOMERASE, FLAVONOIDS
4c9s:F (ARG22) to (LEU140) BACTERIAL CHALCONE ISOMERASE IN OPEN CONFORMATION FROM EUBACTERIUM RAMULUS AT 1.8 A RESOLUTION | ISOMERASE, FLAVONOIDS
3co9:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, NUCLEOTIDE BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSFERASE, ANTIVIRAL, HYDROLASE, NUCLEOTIDE-BINDING
3co9:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, NUCLEOTIDE BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSFERASE, ANTIVIRAL, HYDROLASE, NUCLEOTIDE-BINDING
3cvk:A (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE
3cvk:B (THR287) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE
4clk:A (ARG66) to (GLY150) CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE IN COMPLEX WITH ALPHA,BETA-METHYLENEADENOSINE-5'-TRIPHOSPHATE | LYASE, ADENOSINE-3'\,5'-CYCLIC-MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE
4cly:A (ARG66) to (GLY150) CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE SOAKED WITH BISELENITE | LYASE, NUCLEOTIDE-BINDING
4ry6:A (THR287) to (TYR358) C-TERMINAL MUTANT (W550A) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4ry6:B (THR287) to (TYR358) C-TERMINAL MUTANT (W550A) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
3d32:A (PHE13) to (PHE80) COMPLEX OF GABA(A) RECEPTOR-ASSOCIATED PROTEIN (GABARAP) WITH A SYNTHETIC PEPTIDE | ALPHA-BETA, BETA-GRASP FOLD, CYTOSKELETON, GOLGI APPARATUS, MEMBRANE, MICROTUBULE, TRANSPORT, TRANSPORT PROTEIN
3otd:A (ARG49) to (PRO135) CRYSTAL STRUCTURE OF HUMAN TRNAHIS GUANYLYLTRANSFERASE (THG1)- NAI DERIVATIVE | GUANYLYLTRANSFERASE, POLYMERASE-LIKE PALM DOMAIN, CATALYTIC CARBOXYLATES, TRANSFERASE
3otd:B (ARG49) to (PRO135) CRYSTAL STRUCTURE OF HUMAN TRNAHIS GUANYLYLTRANSFERASE (THG1)- NAI DERIVATIVE | GUANYLYLTRANSFERASE, POLYMERASE-LIKE PALM DOMAIN, CATALYTIC CARBOXYLATES, TRANSFERASE
3p6y:D (ASP94) to (PRO158) CF IM25-CF IM68-UGUAA COMPLEX | RRM DOMAIN, RNA BINDING, NUCLEAR, RNA BINDING PROTEIN-RNA COMPLEX
4doz:A (ASN651) to (VAL717) CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS CMR2 (CAS10) | CYCLASE, CRISPR, ZN, ANTIVIRAL PROTEIN
4dpw:A (GLN259) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS D283A MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH MEVALONATE DIPHOSPHATE AND ATPGS | GHMP KINASE FAMILY, LYASE
4dpw:B (GLU260) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS D283A MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH MEVALONATE DIPHOSPHATE AND ATPGS | GHMP KINASE FAMILY, LYASE
4dpw:C (GLU260) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS D283A MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH MEVALONATE DIPHOSPHATE AND ATPGS | GHMP KINASE FAMILY, LYASE
4dpw:E (GLU260) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS D283A MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH MEVALONATE DIPHOSPHATE AND ATPGS | GHMP KINASE FAMILY, LYASE
4dpw:H (GLU260) to (ASP317) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS EPIDERMIDIS D283A MEVALONATE DIPHOSPHATE DECARBOXYLASE COMPLEXED WITH MEVALONATE DIPHOSPHATE AND ATPGS | GHMP KINASE FAMILY, LYASE
3pco:A (GLN169) to (ARG244) CRYSTAL STRUCTURE OF E. COLI PHENYLALANINE-TRNA SYNTHETASE COMPLEXED WITH PHENYLALANINE AND AMP | AMINOACYLATION, TRNA-BINDING, DNA-BINDING DOMAIN, FOUR-HELIX BUNDLE, AMINOACYL-TRNA SYNTHETASE, ATP-BINDING, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS
3pky:A (MET145) to (SER213) POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D IN COMPLEX WITH DNA, UTP AND MANGANESE. | PROTEIN-DNA COMPLEX, TRANSFERASE-DNA COMPLEX, NUCLEOTIDE-BINDING, POLYMERASE, PRIMASE, TRANSFERASE, NHEJ
3pky:B (MET146) to (SER213) POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D IN COMPLEX WITH DNA, UTP AND MANGANESE. | PROTEIN-DNA COMPLEX, TRANSFERASE-DNA COMPLEX, NUCLEOTIDE-BINDING, POLYMERASE, PRIMASE, TRANSFERASE, NHEJ
3pw2:A (GLU80) to (SER146) TERNARY COMPLEX OF AFLATOXIN B1 ADDUCT MODIFIED DNA (AFB1-FAPY) WITH DNA POLYMERASE IV AND INCOMING DTTP | DNA POLYMERASE, DNA ADDUCT, TERNARY COMPLEX OF DPO4-DNA-DTTP, TRANSFERASE-DNA COMPLEX
3pyd:A (ALA236) to (PRO293) CRYSTAL STRUCTURE OF 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE (ISPE) FROM MYCOBACTERIUM TUBERCULOSIS | KINASE, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, TRANSFERASE
3pyg:A (LEU237) to (PRO293) MYCOBACTERIUM TUBERCULOSIS 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE (ISPE) IN COMPLEX WITH ADP | KINASE, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, TRANSFERASE
4eo8:A (THR287) to (TYR358) HCV NS5B POLYMERASE INHIBITORS: TRI-SUBSTITUTED ACYLHYDRAZINES AS TERTIARY AMIDE BIOISOSTERES | HCV, NS5B, RNA, RNA POLYMERASE, POLYMERASE INHIBITOR, THUMB SITE 2 INHIBITOR, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eo8:B (THR286) to (TYR358) HCV NS5B POLYMERASE INHIBITORS: TRI-SUBSTITUTED ACYLHYDRAZINES AS TERTIARY AMIDE BIOISOSTERES | HCV, NS5B, RNA, RNA POLYMERASE, POLYMERASE INHIBITOR, THUMB SITE 2 INHIBITOR, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4f4y:A (LYS78) to (ALA146) Y-FAMILY DNA POLYMERASE CHIMERA DBH-DPO4-DBH | Y-FAMILY POLYMERASE, TRANSFERASE-DNA COMPLEX
4f50:A (LYS78) to (ALA146) Y-FAMILY DNA POLYMERASE CHIMERA DBH-DBH-DPO4 | Y-FAMILY POLYMERASE, TRANSFERASE-DNA COMPLEX
3qne:A (ASN214) to (SER262) CANDIDA ALBICANS SERYL-TRNA SYNTHETASE | AMINO ACID BIOSYNTHESIS, CTG-CLADE, CODON AMBIGUITY, PATHOGEN, CLASS- II AMINOACYL-TRNA SYNTHETASE FAMILY, TYPE-1 SERYL-TRNA SYNTHETASE SUBFAMILY, TRNA, SERINE, LIGASE
4w8y:A (PRO639) to (ILE716) STRUCTURE OF FULL LENGTH CMR2 FROM PYROCOCCUS FURIOSUS (MANGANESE BOUND FORM) | RNA BINDING PROTEIN, MN BOUND FORM, HD NUCLEASE SITE
4w8y:B (PRO639) to (ILE716) STRUCTURE OF FULL LENGTH CMR2 FROM PYROCOCCUS FURIOSUS (MANGANESE BOUND FORM) | RNA BINDING PROTEIN, MN BOUND FORM, HD NUCLEASE SITE
4fyw:B (ILE25) to (ASN88) E. COLI ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH CTP | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, ALLOSTERY, TRANSFERASE
4fyw:D (ILE25) to (ASN88) E. COLI ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH CTP | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, ALLOSTERY, TRANSFERASE
5jxs:A (ALA302) to (PRO366) MUTANT GC216/7AA OF 3D POLYMERASE FROM FOOT-AND-MOUTH DISEASE VIRUS | RNA-DEPENDENT RNA POLYMERASE PICORNAVIRUS FOOT AND MOUTH DISEASE VIRUS, TRANSFERASE
4gmc:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH A THUMB INHIBITOR | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4gmc:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH A THUMB INHIBITOR | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5tri:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 3-[(4-CHLOROPHENYL)METHOXY]-2-(1-OXO-1,3- DIHYDRO-2H-ISOINDOL-2-YL)BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5tri:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 3-[(4-CHLOROPHENYL)METHOXY]-2-(1-OXO-1,3- DIHYDRO-2H-ISOINDOL-2-YL)BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trj:A (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-{[2-(CARBOXYMETHOXY)BENZENE-1- CARBONYL]AMINO}-3-[(4-CHLOROPHENYL)METHOXY]BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trj:B (THR286) to (TYR358) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-{[2-(CARBOXYMETHOXY)BENZENE-1- CARBONYL]AMINO}-3-[(4-CHLOROPHENYL)METHOXY]BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
8at1:B (ILE25) to (ASN88) CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H | TRANSFERASE (CARBAMOYL-P,ASPARTATE)
8at1:D (ILE25) to (ASN88) CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H | TRANSFERASE (CARBAMOYL-P,ASPARTATE)