4wgi:A (ASN239) to (HIS320) A SINGLE DIASTEREOMER OF A MACROLACTAM CORE BINDS SPECIFICALLY TO MYELOID CELL LEUKEMIA 1 (MCL1) | FUSION PROTEIN, MBP, TRANSPORT PROTEIN, TRANSPORT PROTEIN-INHIBITOR COMPLEX, APOPTOSIS-INHIBITOR COMPLEX
2apl:A (LYS2) to (LEU98) CRYSTAL STRUCTURE OF PROTEIN PG0816 FROM PORPHYROMONAS GINGIVALIS | STRUCTURAL GENOMICS, PORPHYROMONAS GINGIVALIS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
3rrc:A (MET247) to (SER353) CRYSTAL STRUCTURE OF REGION II FROM PLASMODIUM VIVAX DUFFY BINDING PROTEIN | DUFFY BINDING LIKE, RECEPTOR RECOGNITION, DUFFY ANTIGEN RECEPTOR FOR CHEMOKINES, CELL INVASION
2aw5:A (GLN51) to (GLN112) CRYSTAL STRUCTURE OF A HUMAN MALIC ENZYME | ROSSMANN FOLD, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE
4wms:A (ASN239) to (HIS320) STRUCTURE OF APO MBP-MCL1 AT 1.9A | APOPTOSIS, PROTEIN-PROTEIN INTERACTION, CHIMERA PROTEIN
2p1l:C (THR115) to (LEU194) STRUCTURE OF THE BCL-XL:BECLIN 1 COMPLEX | APOPTOSIS; AUTOPHAGY; BECLIN; BH3 DOMAIN; BCL
2p1l:E (THR115) to (LEU194) STRUCTURE OF THE BCL-XL:BECLIN 1 COMPLEX | APOPTOSIS; AUTOPHAGY; BECLIN; BH3 DOMAIN; BCL
2p1l:G (THR115) to (LEU194) STRUCTURE OF THE BCL-XL:BECLIN 1 COMPLEX | APOPTOSIS; AUTOPHAGY; BECLIN; BH3 DOMAIN; BCL
1o0l:A (ALA75) to (TYR151) THE STRUCTURE OF BCL-W REVEALS A ROLE FOR THE C-TERMINAL RESIDUES IN MODULATING BIOLOGICAL ACTIVITY | APOPTOSIS, BCL-2, HELICAL BUNDLE, BINDING GROOVE, BH3
4wyv:C (SER4) to (GLY124) CRYSTAL STRUCTURE OF HUMAN TRANSLIN IN OPEN CONFORMATION | TRANSLIN, OCTOMER, RNA, OPEN, BARREL, RNA BINDING PROTEIN
4wyv:D (SER2) to (GLY124) CRYSTAL STRUCTURE OF HUMAN TRANSLIN IN OPEN CONFORMATION | TRANSLIN, OCTOMER, RNA, OPEN, BARREL, RNA BINDING PROTEIN
4wyv:E (VAL3) to (GLY124) CRYSTAL STRUCTURE OF HUMAN TRANSLIN IN OPEN CONFORMATION | TRANSLIN, OCTOMER, RNA, OPEN, BARREL, RNA BINDING PROTEIN
4wyv:F (VAL3) to (GLY124) CRYSTAL STRUCTURE OF HUMAN TRANSLIN IN OPEN CONFORMATION | TRANSLIN, OCTOMER, RNA, OPEN, BARREL, RNA BINDING PROTEIN
4wyv:H (VAL3) to (GLY124) CRYSTAL STRUCTURE OF HUMAN TRANSLIN IN OPEN CONFORMATION | TRANSLIN, OCTOMER, RNA, OPEN, BARREL, RNA BINDING PROTEIN
1bxl:A (THR115) to (LEU194) STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE | APOPTOSIS, ALTERNATIVE SPLICING, COMPLEX (APOPTOSIS/PEPTIDE)
2bw3:A (LYS354) to (PHE435) THREE-DIMENSIONAL STRUCTURE OF THE HERMES DNA TRANSPOSASE | DNA RECOMBINATION, TRANSPOSITION
3fdm:A (ALA119) to (LEU194) ALPHA/BETA FOLDAMER IN COMPLEX WITH BCL-XL | PROTEIN-PEPTIDE COMPLEX, HELICAL BUNDLE, FOLDAMER, APOPTOSIS, ALTERNATIVE SPLICING, MEMBRANE, MITOCHONDRION, NUCLEUS, TRANSMEMBRANE
3fdm:C (PRO116) to (LEU194) ALPHA/BETA FOLDAMER IN COMPLEX WITH BCL-XL | PROTEIN-PEPTIDE COMPLEX, HELICAL BUNDLE, FOLDAMER, APOPTOSIS, ALTERNATIVE SPLICING, MEMBRANE, MITOCHONDRION, NUCLEUS, TRANSMEMBRANE
2pla:A (ALA196) to (GLU292) CRYSTAL STRUCTURE OF HUMAN GLYCEROL-3-PHOSPHATE DEHYDROGENASE 1-LIKE PROTEIN | DEHYDROGENASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE
4hxi:B (ALA207) to (GLY291) CRYSTAL STRUCTURE OF KLHL3/CUL3 COMPLEX | BTB-BACK, PROTEIN-PROTEIN INTERACTION, PROTEIN BINDING
3sp7:A (TYR120) to (ALA199) CRYSTAL STRUCTURE OF BCL-XL BOUND TO BM903 | BCL-2-LIKE PROTEIN, APOPTOSIS REGULATOR-INHIBITOR COMPLEX
1pj3:A (GLN61) to (GLN122) CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE PYRUVATE, COFACTOR NAD+, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE. | OXIDATIVE DECARBOXYLASE, OXIDOREDUCTASE
1pj3:B (GLN1061) to (GLN1122) CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE PYRUVATE, COFACTOR NAD+, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE. | OXIDATIVE DECARBOXYLASE, OXIDOREDUCTASE
1pj3:C (GLN2061) to (GLN2122) CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE PYRUVATE, COFACTOR NAD+, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE. | OXIDATIVE DECARBOXYLASE, OXIDOREDUCTASE
1pj3:D (GLN3061) to (GLN3122) CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE PYRUVATE, COFACTOR NAD+, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE. | OXIDATIVE DECARBOXYLASE, OXIDOREDUCTASE
1pj4:A (GLN61) to (GLN122) CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE MALATE, ATP, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE. | OXIDATIVE DECARBOXYLASE, OXIDOREDUCTASE
1pj4:B (GLN1061) to (GLN1122) CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE MALATE, ATP, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE. | OXIDATIVE DECARBOXYLASE, OXIDOREDUCTASE
1pj4:C (GLN2061) to (GLN2122) CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE MALATE, ATP, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE. | OXIDATIVE DECARBOXYLASE, OXIDOREDUCTASE
1pj4:D (GLN3061) to (GLN3122) CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE MALATE, ATP, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE. | OXIDATIVE DECARBOXYLASE, OXIDOREDUCTASE
1do8:C (GLN2061) to (GLN2122) CRYSTAL STRUCTURE OF A CLOSED FORM OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME | OXIDATIVE DECARBOXYLASE, FOUR DOMAINS: ONE WITH ROSSMANN FOLD, ONE WITH PARALLEL ALPHA-BETA FOLD, ONE MOSTLY HELICAL, AND ONE MOSTLY EXTENDED, OXIDOREDUCTASE
1pq1:A (PHE131) to (LEU194) CRYSTAL STRUCTURE OF BCL-XL/BIM | BCL-XL/BIM, APOPTOSIS
2qva:B (LEU7) to (LEU124) CRYSTAL STRUCTURE OF DROSOPHILA MELANOGASTER TRANSLIN PROTEIN | TRANSLIN, CRYSTAL STRUCTURE, D. MELANOGASTER, DNA BINDING PROTEIN
2qva:D (LEU7) to (LEU124) CRYSTAL STRUCTURE OF DROSOPHILA MELANOGASTER TRANSLIN PROTEIN | TRANSLIN, CRYSTAL STRUCTURE, D. MELANOGASTER, DNA BINDING PROTEIN
2dr6:B (ASP328) to (ILE438) CRYSTAL STRUCTURE OF A MULTIDRUG TRANSPORTER REVEAL A FUNCTIONALLY ROTATING MECHANISM | MEMBRANE TRANSPORTER, MEMBRANE PROTEIN, MULTIDRUG EFFLUX, DRUG RESISTANCE, TRANSPORTER, EXPORTER, ANTIPORTER
1efk:B (GLN61) to (GLN122) STRUCTURE OF HUMAN MALIC ENZYME IN COMPLEX WITH KETOMALONATE | MALIC ENZYME, CLOSED FORM, QUATERNARY COMPLEX, OXIDOREDUCTASE
1efl:B (GLN61) to (SER121) HUMAN MALIC ENZYME IN A QUATERNARY COMPLEX WITH NAD, MG, AND TARTRONATE | CLOSED FORM, MALIC ENZYME, COMPLEX, TARTRONATE, OXIDOREDUCTASE
1efl:D (GLN61) to (SER121) HUMAN MALIC ENZYME IN A QUATERNARY COMPLEX WITH NAD, MG, AND TARTRONATE | CLOSED FORM, MALIC ENZYME, COMPLEX, TARTRONATE, OXIDOREDUCTASE
4jsn:A (PRO1951) to (ALA2020) STRUCTURE OF MTORDELTAN-MLST8 COMPLEX | HELICAL REPEAT, KINASE, WD40 REPEAT, PROTEIN KINASE, RAPTOR, TRANSFERASE
4yk9:F (ALA119) to (LEU194) COMPLEX STRUCTURE OF BCL-XL AND MUTATED BIM BH3 DOMAIN | BCL-XL, BIM, BH3, COMPLEX, APOPTOSIS
4jsv:A (ARG1950) to (VAL2019) MTOR KINASE STRUCTURE, MECHANISM AND REGULATION. | KINASE, TRANSFERASE
2e8g:A (TYR8) to (GLN94) THE STRUCTURE OF PROTEIN FROM P. HORIKOSHII AT 1.7 ANGSTROM RESOLUTION | OLIGONUCLEOTIDE/OLIGOSACCHARIDE-BINDING FOLD, ALPHA-HELICES BUNDLE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RNA BINDING PROTEIN
2e8g:B (TYR8) to (ALA95) THE STRUCTURE OF PROTEIN FROM P. HORIKOSHII AT 1.7 ANGSTROM RESOLUTION | OLIGONUCLEOTIDE/OLIGOSACCHARIDE-BINDING FOLD, ALPHA-HELICES BUNDLE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RNA BINDING PROTEIN
4k2u:A (PRO38) to (PHE147) CRYSTAL STRUCTURE OF PFEBA-175 F1 IN COMPLEX WITH R218 ANTIBODY FAB FRAGMENT | DBL DOMAIN, IMMUNOGLOBULIN DOMAIN, ANTIBODY FRAGMENT, CELL ATTACHMENT, IMMUNITY, RECEPTOR, LIGAND, EXTRACELLULAR, IMMUNE SYSTEM
4k2u:B (PRO38) to (PHE147) CRYSTAL STRUCTURE OF PFEBA-175 F1 IN COMPLEX WITH R218 ANTIBODY FAB FRAGMENT | DBL DOMAIN, IMMUNOGLOBULIN DOMAIN, ANTIBODY FRAGMENT, CELL ATTACHMENT, IMMUNITY, RECEPTOR, LIGAND, EXTRACELLULAR, IMMUNE SYSTEM
2v6q:A (VAL79) to (ASP156) CRYSTAL STRUCTURE OF A BHRF-1 : BIM BH3 COMPLEX | ALTERNATIVE SPLICING, BCL-2, MEMBRANE, APOPTOSIS
3umi:A (PRO349) to (ILE483) X-RAY STRUCTURE OF THE E2 DOMAIN OF THE HUMAN AMYLOID PRECURSOR PROTEIN (APP) IN COMPLEX WITH ZINC | METAL BINDING SITE, METAL BINDING, CELL SURFACE, SECRETORY PATHWAY, METAL BINDING PROTEIN
4zbi:B (SER247) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbi:D (SER247) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbi:F (ASN239) to (PHE319) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbi:G (GLU240) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbi:H (SER247) to (PHE319) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbi:I (SER247) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbi:K (GLU240) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbi:L (GLU240) to (PHE319) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
1gjh:A (THR125) to (TYR202) HUMAN BCL-2, ISOFORM 2 | APOPTOSIS
4zeq:A (SER63) to (GLU149) CRYSTAL STRUCTURE OF HUMAN BFL-1 IN COMPLEX WITH TBID BH3 PEPTIDE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HX9247 | APOPTOSIS, BCL-2 FAMILY, COMPLEX, BH3 ONLY, STRUCTURAL GENOMICS, PSI- BIOLOGY, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG
2vof:C (SER63) to (PHE148) STRUCTURE OF MOUSE A1 BOUND TO THE PUMA BH3-DOMAIN | BH3, BCL-2, APOPTOSIS, PRO-SURVIVAL, MITOCHONDRION, PROTEIN-PROTEIN COMPLEX
3i1h:A (GLU78) to (GLU149) CRYSTAL STRUCTURE OF HUMAN BFL-1 IN COMPLEX WITH BAK BH3 PEPTIDE | BCL-2 FAMILY, BFL-1, BAK BH3, COMPLEX, APOPTOSIS, PRO-SURVIVAL PROTEIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, MEMBRANE, METAL- BINDING, TRANSMEMBRANE
1gz4:B (GLN61) to (GLN122) MOLECULAR MECHANISM OF THE REGULATION OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME BY ATP AND FUMARATE | ALLOSTERIC REGULATION, ENERGY METABOLISM, KINETICS, OXIDOREDUCTASE
1gz4:C (GLN61) to (GLN122) MOLECULAR MECHANISM OF THE REGULATION OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME BY ATP AND FUMARATE | ALLOSTERIC REGULATION, ENERGY METABOLISM, KINETICS, OXIDOREDUCTASE
3ibv:B (SER36) to (GLU100) KARYOPHERIN CYTOSOLIC STATE | KARYOPHERIN, EXPORTIN, HEAT REPEAT, CYTOPLASM, NUCLEUS, RNA- BINDING, TRANSPORT, TRNA PROCESSING, TRNA-BINDING, RNA BINDING PROTEIN
3inq:A (TYR120) to (LEU194) CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH W1191542 | APOPTOSIS, ALTERNATIVE SPLICING, MEMBRANE, MITOCHONDRION, NUCLEUS, TRANSMEMBRANE
3inq:B (TYR120) to (LEU194) CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH W1191542 | APOPTOSIS, ALTERNATIVE SPLICING, MEMBRANE, MITOCHONDRION, NUCLEUS, TRANSMEMBRANE
3io8:A (THR118) to (LEU194) BIML12F IN COMPLEX WITH BCL-XL | HELICAL BUNDLE, BCL-2-LIKE FOLD, ALTERNATIVE SPLICING, APOPTOSIS, MEMBRANE, MITOCHONDRION, NUCLEUS, TRANSMEMBRANE, PHOSPHOPROTEIN
3io8:C (ALA119) to (LEU194) BIML12F IN COMPLEX WITH BCL-XL | HELICAL BUNDLE, BCL-2-LIKE FOLD, ALTERNATIVE SPLICING, APOPTOSIS, MEMBRANE, MITOCHONDRION, NUCLEUS, TRANSMEMBRANE, PHOSPHOPROTEIN
3vle:A (HIS339) to (ARG381) CRYSTAL STRUCTURE OF YEAST PROTEASOME INTERACTING PROTEIN | HEAT REPEAT, RPT1, CHAPERONE
2wh6:A (VAL79) to (ILE154) CRYSTAL STRUCTURE OF ANTI-APOPTOTIC BHRF1 IN COMPLEX WITH THE BIM BH3 DOMAIN | MITOCHONDRION, EARLY PROTEIN, TRANSMEMBRANE, VIRAL PROTEIN, APOPTOSIS
5a31:N (GLN370) to (LEU442) STRUCTURE OF THE HUMAN APC-CDH1-HSL1-UBCH10 COMPLEX. | UBIQUITINATION, CELL CYCLE, APC/C
2ims:A (THR103) to (LEU181) THE X-RAY STRUCTURE OF A BAK HOMODIMER REVEALS AN INHIBITORY ZINC BINDING SITE | DIMER, APOPTOSIS
2imt:A (THR103) to (ASN182) THE X-RAY STRUCTURE OF A BAK HOMODIMER REVEALS AN INHIBITORY ZINC BINDING SITE | DIMER, APOPTOSIS
5agw:A (ALA126) to (TYR202) BCL-2 ALPHA BETA-1 COMPLEX | BCL-2, FOLDAMER, BIM, APOPTOSIS
3wiy:B (SER247) to (PHE319) CRYSTAL STRUCTURE OF MCL-1 IN COMPLEX WITH COMPOUND 10 | REGULATION, APOPTOSIS
3wiy:D (GLU240) to (HIS320) CRYSTAL STRUCTURE OF MCL-1 IN COMPLEX WITH COMPOUND 10 | REGULATION, APOPTOSIS
2xa0:A (ALA126) to (TYR202) CRYSTAL STRUCTURE OF BCL-2 IN COMPLEX WITH A BAX BH3 PEPTIDE | APOPTOSIS, CELL DEATH
2xa0:B (THR122) to (TYR202) CRYSTAL STRUCTURE OF BCL-2 IN COMPLEX WITH A BAX BH3 PEPTIDE | APOPTOSIS, CELL DEATH
4mt1:A (LYS329) to (GLN435) CRYSTAL STRUCTURE OF THE NEISSERIA GONORRHOEAE MTRD INNER MEMBRANE MULTIDRUG EFFLUX PUMP | TRANSMEMBRANE HELIX, MEMBRANE PROTEIN, TRANPORT PROTEIN
3wxv:A (SER197) to (VAL297) CRYSTAL STRUCTURE OF THE HUMAN ADIPONECTIN RECEPTOR 1 | PAQR FAMILY, ADIPONECTIN, OSMOTIN, APPL1, APPL2, MEMBRANE, MEMBRANE PROTEIN-IMMUNE SYSTEM COMPLEX
5b1a:E (GLU44) to (GLY105) BOVINE HEART CYTOCHROME C OXIDASE IN THE FULLY OXIDIZED STATE AT 1.5 ANGSTROM RESOLUTION | OXIDOREDUCTASE, PROTON PUMP, HEME, RESPIRATORY CHAIN
2jcn:A (ALA107) to (ASN182) THE CRYSTAL STRUCTURE OF BAK1 - A MITOCHONDRIAL APOPTOSIS REGULATOR | APOPTOSIS, MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION, OLIGOMERIZATION, CYTOCHROME C RELEASE, MEMBRANE, TRANSMEMBRANE
3zk6:A (TYR120) to (LEU194) CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH INHIBITOR (COMPOUND 2). | APOPTOSIS, INHIBITOR, BCL-2 FAMILY
3zk6:B (TYR120) to (LEU194) CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH INHIBITOR (COMPOUND 2). | APOPTOSIS, INHIBITOR, BCL-2 FAMILY
3zln:A (GLN121) to (LEU194) CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH INHIBITOR (COMPOUND 3). | APOPTOSIS, INHIBITOR
3zlo:A (TYR120) to (LEU194) CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH INHIBITOR (COMPOUND 6). | APOPTOSIS, INHIBITOR
3zlr:A (GLN121) to (LEU194) CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH INHIBITOR (WEHI-539). 539). | APOPTOSIS, INHIBITOR
3zlr:B (GLN121) to (LEU194) CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH INHIBITOR (WEHI-539). 539). | APOPTOSIS, INHIBITOR
1wpq:A (VAL194) to (GLU290) TERNARY COMPLEX OF GLYCEROL 3-PHOSPHATE DEHYDROGENASE 1 WITH NAD AND DIHYDROXYACTONE | NAD, GPD1, DEHYDROGENASE, DIHYDROXYACTONE COMPLEX, OXIDOREDUCTASE
1wpq:B (ASP195) to (GLU290) TERNARY COMPLEX OF GLYCEROL 3-PHOSPHATE DEHYDROGENASE 1 WITH NAD AND DIHYDROXYACTONE | NAD, GPD1, DEHYDROGENASE, DIHYDROXYACTONE COMPLEX, OXIDOREDUCTASE
1key:B (SER2) to (GLY124) CRYSTAL STRUCTURE OF MOUSE TESTIS/BRAIN RNA-BINDING PROTEIN (TB-RBP) | RNA-BINDING PROTEIN, TETRAMER/OCTAMER ASSEMBLY, APOTB-RBP, RNA BINDING PROTEIN
1key:C (SER2) to (GLY124) CRYSTAL STRUCTURE OF MOUSE TESTIS/BRAIN RNA-BINDING PROTEIN (TB-RBP) | RNA-BINDING PROTEIN, TETRAMER/OCTAMER ASSEMBLY, APOTB-RBP, RNA BINDING PROTEIN
2lp8:A (PRO76) to (LEU154) SOLUTION STRUCTURE OF AN APOPTOSIS ACTIVATING PHOTOSWITCHABLE BAK PEPTIDE BOUND TO BCL-XL | APOPTOSIS, AZOBENZENE, PHOTOSWITCH, PHOTOCONTROL, APOPTOSIS INHIBITOR, APOPTOSIS-APOPTOSIS ACTIVATOR COMPLEX
3jbz:A (ARG1950) to (VAL2019) CRYSTAL STRUCTURE OF MTOR DOCKED INTO EM MAP OF DIMERIC ATM KINASE | MTOR, PIKK, TRANSFERASE
2m5b:A (ASN106) to (ASN182) THE NMR STRUCTURE OF THE BID-BAK COMPLEX | BCL-2 FAMILY EFFECTOR BAK, BH3-ONLY PROTEIN BID, EFFECTOR DIRECT ACTIVATION, NMR SOLUTION STRUCTURE OF BID-BAK COMPLEX, MITOCHONDRIAL OUTER MEMBRANE PREMEABILIZATION, APOPTOSIS
2me8:A (TYR123) to (ASN200) SOLUTION STRUCTURE OF BCL-XL IN ITS P53-BOUND CONFORMATION DETERMINED WITH SELECTIVE ISOTOPE LABELLING OF I,L,V SIDECHAINS | BCL-XL, P53, APOPTOSIS, BCL-2 FAMILY, CYTOPLASMIC P53, SELECTIVE LABELING
2me9:A (ALA122) to (LEU197) SOLUTION STRUCTURE OF BCL-XL CONTAINING THE ALPHA1-ALPHA2 DISORDERED LOOP DETERMINED WITH SELECTIVE ISOTOPE LABELLING OF I,L,V SIDECHAINS | BCL-XL, P53, APOPTOSIS, BCL-2 FAMILY, CYTOPLASMIC P53, SELECTIVE LABELING
4nuu:A (MET247) to (SER353) HETEROTRIMER STRUCTURE OF REGION II FROM PLASMODIUM VIVAX DUFFY BINDING PROTEIN (PVDBP) BOUND TO THE ECTODOMAIN OF THE DUFFY ANTIGEN RECEPTOR FOR CHEMOKINES (DARC) | DUFFY BINDING LIKE (DBL) DOMAIN FOLD, GPCR, ADHESION, INVASION, RED BLOOD CELL BINDING, CHEMOKINE BINDING, DUFFY ANTIGEN RECEPTOR FOR CHEMOKINES, MEMBRANE, MEMBRANE PROTEIN, PROTEIN BINDING, CELL INVASION
4nuv:A (MET247) to (SER353) HETEROTETRAMER STRUCTURE OF REGION II FROM PLASMODIUM VIVAX DUFFY BINDING PROTEIN (PVDBP) BOUND TO THE ECTODOMAIN OF THE DUFFY ANTIGEN RECEPTOR FOR CHEMOKINES (DARC) | DUFFY BINDING LIKE (DBL) DOMAIN FOLD, GPCR, ADHESION, INVASION, RED BLOOD CELL BINDING, CHEMOKINE BINDING, DUFFY ANTIGEN RECEPTOR FOR CHEMOKINES, MEMBRANE, MEMBRANE PROTEIN, PROTEIN BINDING, CELL INVASION
4nuv:B (MET247) to (SER353) HETEROTETRAMER STRUCTURE OF REGION II FROM PLASMODIUM VIVAX DUFFY BINDING PROTEIN (PVDBP) BOUND TO THE ECTODOMAIN OF THE DUFFY ANTIGEN RECEPTOR FOR CHEMOKINES (DARC) | DUFFY BINDING LIKE (DBL) DOMAIN FOLD, GPCR, ADHESION, INVASION, RED BLOOD CELL BINDING, CHEMOKINE BINDING, DUFFY ANTIGEN RECEPTOR FOR CHEMOKINES, MEMBRANE, MEMBRANE PROTEIN, PROTEIN BINDING, CELL INVASION
5c6h:A (ASN239) to (PHE319) MCL-1 COMPLEXED WITH MULE | COMPLEX. MCL-1, MULE, BH3, APOPTOSIS-APOPTOSIS REGULATOR COMPLEX
5c6h:C (ASN239) to (HIS320) MCL-1 COMPLEXED WITH MULE | COMPLEX. MCL-1, MULE, BH3, APOPTOSIS-APOPTOSIS REGULATOR COMPLEX
5c6h:U (ASN239) to (PHE319) MCL-1 COMPLEXED WITH MULE | COMPLEX. MCL-1, MULE, BH3, APOPTOSIS-APOPTOSIS REGULATOR COMPLEX
4a0c:C (ILE380) to (GLU467) STRUCTURE OF THE CAND1-CUL4B-RBX1 COMPLEX | TRANSCRIPTION, LIGASE, UBIQUITIN, CELL CYCLE, DNA DAMAGE REPAIR
4a0l:E (GLU386) to (ASN468) STRUCTURE OF DDB1-DDB2-CUL4B-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX | LIGASE-DNA-BINDING PROTEIN-DNA COMPLEX
4a0l:H (GLU386) to (ASN468) STRUCTURE OF DDB1-DDB2-CUL4B-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX | LIGASE-DNA-BINDING PROTEIN-DNA COMPLEX
4a1u:A (THR118) to (LEU194) CRYSTAL STRUCTURE OF ALPHA-BETA-FOLDAMER 2C IN COMPLEX WITH BCL-XL | APOPTOSIS, ALPHA-HELIX, BH3, MIMICRY
4a1w:A (THR115) to (LEU194) CRYSTAL STRUCTURE OF ALPHA-BETA FOLDAMER 4C IN COMPLEX WITH BCL-XL | APOPTOSIS-INHIBITOR COMPLEX, MIMICRY
4a1w:B (THR115) to (LEU194) CRYSTAL STRUCTURE OF ALPHA-BETA FOLDAMER 4C IN COMPLEX WITH BCL-XL | APOPTOSIS-INHIBITOR COMPLEX, MIMICRY
2yq6:A (PRO116) to (LEU194) STRUCTURE OF BCL-XL BOUND TO BIMSAHB | CONSTRAINED PEPTIDE, APOPTOSIS, BCL-2 FAMILY
2yq7:A (PRO116) to (LEU194) STRUCTURE OF BCL-XL BOUND TO BIMLOCK | CONSTRAINED PEPTIDE, APOPTOSIS, BCL-2 FAMILY
2yv6:A (THR103) to (ASN182) CRYSTAL STRUCTURE OF HUMAN BCL-2 FAMILY PROTEIN BAK | STRUCTURE GENOMICS, BCL DOMAIN, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, APOPTOSIS
2o1y:A (TYR124) to (LEU198) SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-XL IN COMPLEX WITH AN ACYL-SULFONAMIDE-BASED LIGAND | APOPTOSIS, COMPLEX, BCL, NMR
2o2f:A (THR122) to (TYR199) SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-2 IN COMPLEX WITH AN ACYL-SULFONAMIDE-BASED LIGAND | APOPTOSIS, COMPLEX, BCL, NMR
2o2n:A (TYR124) to (TYR199) SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-XL IN COMPLEX WITH AN ACYL-SULFONAMIDE-BASED LIGAND | APOPTOSIS, COMPLEX, BCL, NMR
4a3t:A (HIS339) to (LEU382) YEAST REGULATORY PARTICLE PROTEASOME ASSEMBLY CHAPERONE HSM3 | CHAPERONE
4a3t:B (HIS339) to (LEU382) YEAST REGULATORY PARTICLE PROTEASOME ASSEMBLY CHAPERONE HSM3 | CHAPERONE
3k96:A (ASP181) to (GLY278) 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF GLYCEROL-3-PHOSPHATE DEHYDROGENASE (GPSA) FROM COXIELLA BURNETII | GLYCEROL-3-PHOSPHATE DEHYDROGENASE, GPSA, IDP01976, NAD, OXIDOREDUCTASE, PHOSPHOLIPID BIOSYNTHESIS, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
4oq5:F (GLU240) to (PHE319) CRYSTAL STRUCTURE OF HUMAN MCL-1 BOUND TO INHIBITOR 4-(4- METHYLNAPHTHALEN-1-YL)-2-{[(4-PHENOXYPHENYL)SULFONYL]AMINO}BENZOIC ACID | APOPTOSIS-INHIBITOR COMPLEX
4oyd:A (VAL79) to (ASP156) CRYSTAL STRUCTURE OF A COMPUTATIONALLY DESIGNED INHIBITOR OF AN EPSTEIN-BARR VIRAL BCL-2 PROTEIN | INHIBITOR, COMPLEX, APOPTOSIS, VIRAL PROTEIN-INHIBITOR COMPLEX
4oyd:C (VAL79) to (GLU155) CRYSTAL STRUCTURE OF A COMPUTATIONALLY DESIGNED INHIBITOR OF AN EPSTEIN-BARR VIRAL BCL-2 PROTEIN | INHIBITOR, COMPLEX, APOPTOSIS, VIRAL PROTEIN-INHIBITOR COMPLEX
4ady:A (GLY312) to (HIS375) CRYSTAL STRUCTURE OF 26S PROTEASOME SUBUNIT RPN2 | PROTEIN BINDING, RPN1, PC REPEAT
4p1t:A (PRO1625) to (GLU1743) CRYSTAL STRUCTURE OF THE DBL3X-DBL4EPSILON DOUBLE DOMAIN FROM THE EXTRACELLULAR PART OF VAR2CSA PFEMP1 FROM PLASMODIUM FALCIPARUM | PFEMP1, CSA, DBL FOLD, MEMBRANE PROTEIN
3kz0:B (VAL243) to (HIS320) MCL-1 COMPLEX WITH MCL-1-SPECIFIC SELECTED PEPTIDE | BCL-2, BH3, MITOCHONDRION, APOPTOSIS, ANTI-APOPTOTIC
1ysn:A (TYR124) to (LEU198) SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-XL COMPLEXED WITH AN ACYL-SULFONAMIDE-BASED LIGAND | COMPLEX, APOPTOSIS
4pu2:A (ASP740) to (ALA796) CRYSTAL STRUCTURE OF AMINOPEPTIDASE N IN COMPLEX WITH THE PHOSPHONIC ACID ANALOGUE OF LEUCINE L-(R)-LEUP | APN, AMINOPEPTIDASE N, L-(R)-LEUP, PSI-BIOLOGY, STRUCTURAL GENOMICS, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, HYDROLASE, AMINOPEPTIDASE
4ap2:B (GLU206) to (ASN290) CRYSTAL STRUCTURE OF THE HUMAN KLHL11-CUL3 COMPLEX AT 2.8A RESOLUTION | UBIQUITINATION, E3 LIGASE, CELL CYCLE
4apf:B (ALA207) to (GLY291) CRYSTAL STRUCTURE OF THE HUMAN KLHL11-CUL3 COMPLEX AT 3.1A RESOLUTION | UBIQUITINATION, E3 LIGASE, CELL CYCLE
5dyf:A (ASP740) to (ALA796) THE CRYSTAL STRUCTURE OF AMINOPEPTIDASE N IN COMPLEX WITH N-BENZYL-1, 2-DIAMINOETHYLPHOSPHONIC ACID | AMINOPEPTIDASEN, INHIBITOR COMPLEX, N-BENZYL-1, 2- DIAMINOETHYLPHOSPHONIC ACID, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG
1zrl:A (PRO38) to (PHE147) CRYSTAL STRUCTURE OF EBA-175 REGION II (RII) | EBA-175, RII, DBL, ERYTHROCYTE, INVASION, HOST, MALARIA, DISEASE, GLYCOPHORIN, GLYCAN, SIALIC ACID, CELL INVASION
1zy3:A (ALA74) to (GLY151) STRUCTURAL MODEL OF COMPLEX OF BCL-W PROTEIN WITH BID BH3- PEPTIDE | APOPTOSIS, BCL-W, BH3-PEPTIDE
3axj:A (ASP8) to (LEU124) HIGH RESOLUTION CRYSTAL STRUCTURE OF C3PO | TRANSLIN/TRAX HETERODIMER, PASSENGER RNA CLEAVAGE, RNASE, DNA BINDING PROTEIN
3axj:B (SER28) to (GLN159) HIGH RESOLUTION CRYSTAL STRUCTURE OF C3PO | TRANSLIN/TRAX HETERODIMER, PASSENGER RNA CLEAVAGE, RNASE, DNA BINDING PROTEIN
4b4s:A (ASN62) to (THR161) CRYSTAL STRUCTURE OF A PRO-SURVIVAL BCL-2:BIM BH3 COMPLEX | APOPTOSIS
4qhp:A (ASP740) to (ALA796) CRYSTAL STRUCTURE OF AMINOPEPTIDASE N IN COMPLEX WITH THE PHOSPHINIC DIPEPTIDE ANALOGUE LL-(R,S)-HPHEP[CH2]PHE(4-CH2NH2) | ZN-DEPENDENT, APN, (S)-2-[4-(AMINOMETHYL)BENZYL]-3-[(R)-1-AMINO-3- PHENYLPROPYL(HYDROXY)PHOSPHORYL]PROPANOIC ACID, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qme:A (ASP740) to (ALA796) CRYSTAL STRUCTURE OF AMINOPEPTIDASE N IN COMPLEX WITH THE PHOSPHINIC DIPEPTIDE ANALOGUE LL-(R,S)-HPHEP[CH2]PHE | APN, ALANINE AMINOPEPTIDASE, M1 PEPTIDASE, 3-{[(R)-1-AMINO-3- PHENYLPROPYL](HYDROXY)PHOSPHORYL}-(S)-2-BENZYLPROPANOIC ACID, HYDROLASE
4qvx:A (TYR120) to (LEU194) DISCOVERY OF A POTENT AND SELECTIVE BCL-XL INHIBITOR THAT DEMONSTRATES THROMBOCYTOPENIA AND INHIBITS TUMOR GROWTH IN VIVO | 8 ALPHA HELICES, ANTI-APOPTOTIC, PRO-APOPTOTIC, APOPTOSIS-INHIBITOR COMPLEX
4qvx:B (TYR120) to (LEU194) DISCOVERY OF A POTENT AND SELECTIVE BCL-XL INHIBITOR THAT DEMONSTRATES THROMBOCYTOPENIA AND INHIBITS TUMOR GROWTH IN VIVO | 8 ALPHA HELICES, ANTI-APOPTOTIC, PRO-APOPTOTIC, APOPTOSIS-INHIBITOR COMPLEX
4bpk:B (PRO116) to (TYR195) BCL-XL BOUND TO ALPHA BETA PUMA BH3 PEPTIDE 5 | APOPTOSIS
5fc4:A (LEU246) to (PHE319) MCL-1 COMPLEXED WITH SMALL MOLECULE INHIBITOR | MCL-1, INHIBITOR, APOPTOSIS-APOPTOSIS INHIBITOR COMPLEX
5fcg:A (THR83) to (GLY164) CRYSTAL STRUCTURE OF BCL-2 IN COMPLEX WITH HBX-BH3 MOTIF | COMPLEX, APOPTOSIS
5fdr:B (SER247) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULE INHIBITOR | MCL-1, INHIBITOR, APOPTOSIS-APOPTOSIS INHIBITOR COMPLEX
5fdr:D (SER247) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULE INHIBITOR | MCL-1, INHIBITOR, APOPTOSIS-APOPTOSIS INHIBITOR COMPLEX
4c5d:A (TYR120) to (LEU194) CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH BENZOYLUREA COMPOUND (42) | APOPTOSIS, BCL-2
4c5d:B (GLN121) to (TYR195) CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH BENZOYLUREA COMPOUND (42) | APOPTOSIS, BCL-2
5fmi:A (THR103) to (GLY184) HUMAN BAK Q77L | BAK, APOPTOSIS, BCL-2 FAMILY
5fmj:A (THR115) to (LEU194) BCL-XL WITH MOUSE BAK BH3 Q75L COMPLEX | BCL-XL, BAK, BH3 DOMAIN, APOPTOSIS, BCL-2 FAMILY
5fmk:A (PHE131) to (LEU194) BCL-XL WITH BAK BH3 COMPLEX | BCL-XL, BAK, BH3 DOMAIN, APOPTOSIS, BCL-2 FAMILY
3cml:A (PRO1266) to (ILE1408) CRYSTAL STRUCTURE OF THE DBL3X DOMAIN OF THE PLASMODIUM FALCIPURUM VAR2CSA PROTEIN | DBL3X, VAR2CSA, CHONDROITIN-SULFATE BINDING DOMAIN, MEMBRANE PROTEIN
4tuh:A (TYR120) to (LEU194) BCL-XL IN COMPLEX WITH INHIBITOR (COMPOUND 10) | APOPTOSIS, DRUG DESIGN
4tuh:B (TYR120) to (LEU194) BCL-XL IN COMPLEX WITH INHIBITOR (COMPOUND 10) | APOPTOSIS, DRUG DESIGN
4tuh:C (TYR120) to (LEU194) BCL-XL IN COMPLEX WITH INHIBITOR (COMPOUND 10) | APOPTOSIS, DRUG DESIGN
4tuh:D (TYR120) to (LEU194) BCL-XL IN COMPLEX WITH INHIBITOR (COMPOUND 10) | APOPTOSIS, DRUG DESIGN
4tuh:E (GLN121) to (GLY196) BCL-XL IN COMPLEX WITH INHIBITOR (COMPOUND 10) | APOPTOSIS, DRUG DESIGN
4tuh:F (TYR120) to (LEU194) BCL-XL IN COMPLEX WITH INHIBITOR (COMPOUND 10) | APOPTOSIS, DRUG DESIGN
4tuh:G (TYR120) to (LEU194) BCL-XL IN COMPLEX WITH INHIBITOR (COMPOUND 10) | APOPTOSIS, DRUG DESIGN
4tuh:H (GLN121) to (LEU194) BCL-XL IN COMPLEX WITH INHIBITOR (COMPOUND 10) | APOPTOSIS, DRUG DESIGN
4d5r:A (ASP87) to (ARG160) STRUCTURE OF N-TERMINALLY TRUNCATED A49 FROM VACCINIA VIRUS WESTERN RESERVE | VIRAL PROTEIN, POXVIRUS, B CELL LYMPHOMA 2 (BCL-2) FAMILY, INNATE IMMUNE MODULATOR, NUCLEAR FACTOR KAPPA B (NF-KB)
4d5t:B (ASP87) to (ARG160) STRUCTURE OF N-TERMINALLY TRUNCATED A49 FROM VACCINIA VIRUS WESTERN RESERVE | VIRAL PROTEIN, POX VIRUS, B CELL LYMPHOMA 2 (BCL-2) FAMILY, INNATE IMMUNE MODULATOR, NUCLEAR FACTOR KAPPA B (NF-KB)
4d5t:D (ASP87) to (ARG160) STRUCTURE OF N-TERMINALLY TRUNCATED A49 FROM VACCINIA VIRUS WESTERN RESERVE | VIRAL PROTEIN, POX VIRUS, B CELL LYMPHOMA 2 (BCL-2) FAMILY, INNATE IMMUNE MODULATOR, NUCLEAR FACTOR KAPPA B (NF-KB)
4d5t:E (ASP87) to (ARG160) STRUCTURE OF N-TERMINALLY TRUNCATED A49 FROM VACCINIA VIRUS WESTERN RESERVE | VIRAL PROTEIN, POX VIRUS, B CELL LYMPHOMA 2 (BCL-2) FAMILY, INNATE IMMUNE MODULATOR, NUCLEAR FACTOR KAPPA B (NF-KB)
4d5t:F (ASP87) to (ARG160) STRUCTURE OF N-TERMINALLY TRUNCATED A49 FROM VACCINIA VIRUS WESTERN RESERVE | VIRAL PROTEIN, POX VIRUS, B CELL LYMPHOMA 2 (BCL-2) FAMILY, INNATE IMMUNE MODULATOR, NUCLEAR FACTOR KAPPA B (NF-KB)
4d5t:G (ASP87) to (ARG160) STRUCTURE OF N-TERMINALLY TRUNCATED A49 FROM VACCINIA VIRUS WESTERN RESERVE | VIRAL PROTEIN, POX VIRUS, B CELL LYMPHOMA 2 (BCL-2) FAMILY, INNATE IMMUNE MODULATOR, NUCLEAR FACTOR KAPPA B (NF-KB)
4d5t:H (ASP87) to (ARG160) STRUCTURE OF N-TERMINALLY TRUNCATED A49 FROM VACCINIA VIRUS WESTERN RESERVE | VIRAL PROTEIN, POX VIRUS, B CELL LYMPHOMA 2 (BCL-2) FAMILY, INNATE IMMUNE MODULATOR, NUCLEAR FACTOR KAPPA B (NF-KB)
4uf3:A (ILE79) to (ILE136) DEERPOX VIRUS DPV022 IN COMPLEX WITH BIM BH3 | VIRAL PROTEIN, DPV022, DEERPOX VIRUS, APOPTOSIS, BCL-2, BIM BH3
4eoz:B (GLU206) to (GLY291) CRYSTAL STRUCTURE OF THE SPOP BTB DOMAIN COMPLEXED WITH THE CUL3 N- TERMINAL DOMAIN | E3 UBIQUITIN LIGASE, NUCLEUS, PROTEIN BINDING
4eoz:D (GLU206) to (GLY283) CRYSTAL STRUCTURE OF THE SPOP BTB DOMAIN COMPLEXED WITH THE CUL3 N- TERMINAL DOMAIN | E3 UBIQUITIN LIGASE, NUCLEUS, PROTEIN BINDING
3qb5:A (SER4) to (GLY124) HUMAN C3PO COMPLEX IN THE PRESENCE OF MNSO4 | 7 ALPHA HELICAL BUNDLE, RIBONUCLEASE, HYDROLASE
3qbr:X (LYS89) to (GLY168) BAKBH3 IN COMPLEX WITH SJA | HELICAL BUNDLE, BCL-2-LIKE FOLD, APOPTOSIS
3qkd:B (ALA119) to (LEU194) CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH A QUINAZOLINE SULFONAMIDE INHIBITOR | BCL-2 FAMILY FOLD, APOPTOSIS-INHIBITOR COMPLEX
4fgv:A (ASN614) to (GLU678) CRYSTAL STRUCTURE OF FREE CRM1 (CRYSTAL FORM 1) | HEAT REPEAT PROTEIN, IMPORTIN-BETA SUPERFAMILY, NUCLEAR EXPORT OF NUMEROUS PROTEIN AND RNP CARGOES, TRANSPORT PROTEIN
3r85:A (THR115) to (LEU194) CRYSTAL STRUCTURE OF HUMAN SOUL BH3 DOMAIN IN COMPLEX WITH BCL-XL | BCL-2-LIKE PROTEIN, INHIBITOR OF CELL DEATH, SOUL PROTEIN, APOPTOSIS
3riu:C (VAL31) to (GLU162) CRYSTAL STRUCTURE OF DROSOPHILA HEXAMERIC C3PO FORMED BY TRUNCATED TRANSLIN AND TRAX | TRANSLIN-FOLD, RIBONUCLEASE, RISC ACTIVATOR, NUCLEUS, HYDROLASE
4g35:A (PHE246) to (PHE319) MCL-1 IN COMPLEX WITH A BIPHENYL CROSS-LINKED NOXA PEPTIDE. | APOPTOSIS, BH3 DOMAIN, BCL-2 FAMILY, APOPTOSIS-INHIBITOR COMPLEX
5lcw:N (GLN370) to (LEU442) CRYO-EM STRUCTURE OF THE ANAPHASE-PROMOTING COMPLEX/CYCLOSOME, IN COMPLEX WITH THE MITOTIC CHECKPOINT COMPLEX (APC/C-MCC) AT 4.2 ANGSTROM RESOLUTION | COMPLEX, UBIQUITIN, E3 LIGASE, UBIQUITIN LIGASE, CULLIN, RING, CELL CYCLE, MITOSIS, SPINDLE CHECKPOINT, DEGRON
5sy1:A (PRO137) to (ASN215) STRUCTURE OF THE STRA6 RECEPTOR FOR RETINOL UPTAKE IN COMPLEX WITH CALMODULIN | VITAMIN A, RETINOL, STRA6, MEMBRANE, MEMBRANE PROTEIN-CALCIUM BINDING PROTEIN COMPLEX
5sy1:B (PRO137) to (ASN215) STRUCTURE OF THE STRA6 RECEPTOR FOR RETINOL UPTAKE IN COMPLEX WITH CALMODULIN | VITAMIN A, RETINOL, STRA6, MEMBRANE, MEMBRANE PROTEIN-CALCIUM BINDING PROTEIN COMPLEX
4wmr:A (GLU240) to (PHE318) STRUCTURE OF MCL1 BOUND TO BRD INHIBITOR LIGAND 1 AT 1.7A | APOPTOSIS, PROTEIN-PROTEIN INTERACTION
2ovr:B (GLU2287) to (ARG2366) STRUCTURE OF THE SKP1-FBW7-CYCLINEDEGN COMPLEX | F-BOX; WD40 DOMAINS; DOUBLE PHOSPHORYLATION, TRANSCRIPTION-CELL CYCLE COMPLEX
4hw2:A (SER247) to (HIS320) DISCOVERY OF POTENT MCL-1 INHIBITORS USING FRAGMENT-BASED METHODS AND STRUCTURE-BASED DESIGN | REGULATION OF APOPTOSIS, MAINTENANCE OF VIABILITY, APOPTOSIS, APOPTOSIS-INHIBITOR COMPLEX
4hw2:B (SER247) to (PHE319) DISCOVERY OF POTENT MCL-1 INHIBITORS USING FRAGMENT-BASED METHODS AND STRUCTURE-BASED DESIGN | REGULATION OF APOPTOSIS, MAINTENANCE OF VIABILITY, APOPTOSIS, APOPTOSIS-INHIBITOR COMPLEX
4hw2:C (GLU240) to (HIS320) DISCOVERY OF POTENT MCL-1 INHIBITORS USING FRAGMENT-BASED METHODS AND STRUCTURE-BASED DESIGN | REGULATION OF APOPTOSIS, MAINTENANCE OF VIABILITY, APOPTOSIS, APOPTOSIS-INHIBITOR COMPLEX
3fdl:A (ALA119) to (LEU194) BIM BH3 PEPTIDE IN COMPLEX WITH BCL-XL | HELICAL BUNDLE, PEPTIDE-PROTEIN COMPLEX, APOPTOSIS, ALTERNATIVE SPLICING, MEMBRANE, MITOCHONDRION, NUCLEUS, TRANSMEMBRANE, PHOSPHOPROTEIN
4hw3:B (GLU240) to (HIS320) DISCOVERY OF POTENT MCL-1 INHIBITORS USING FRAGMENT-BASED METHODS AND STRUCTURE-BASED DESIGN | REGULATION OF APOPTOSIS, MAINTENANCE OF VIABILITY, APOPTOSIS, APOPTOSIS-INHIBITOR COMPLEX
4hw3:C (SER247) to (HIS320) DISCOVERY OF POTENT MCL-1 INHIBITORS USING FRAGMENT-BASED METHODS AND STRUCTURE-BASED DESIGN | REGULATION OF APOPTOSIS, MAINTENANCE OF VIABILITY, APOPTOSIS, APOPTOSIS-INHIBITOR COMPLEX
4hw3:D (SER247) to (PHE319) DISCOVERY OF POTENT MCL-1 INHIBITORS USING FRAGMENT-BASED METHODS AND STRUCTURE-BASED DESIGN | REGULATION OF APOPTOSIS, MAINTENANCE OF VIABILITY, APOPTOSIS, APOPTOSIS-INHIBITOR COMPLEX
4hw3:E (SER247) to (HIS320) DISCOVERY OF POTENT MCL-1 INHIBITORS USING FRAGMENT-BASED METHODS AND STRUCTURE-BASED DESIGN | REGULATION OF APOPTOSIS, MAINTENANCE OF VIABILITY, APOPTOSIS, APOPTOSIS-INHIBITOR COMPLEX
4hw3:F (SER247) to (HIS320) DISCOVERY OF POTENT MCL-1 INHIBITORS USING FRAGMENT-BASED METHODS AND STRUCTURE-BASED DESIGN | REGULATION OF APOPTOSIS, MAINTENANCE OF VIABILITY, APOPTOSIS, APOPTOSIS-INHIBITOR COMPLEX
4hw3:G (SER247) to (HIS320) DISCOVERY OF POTENT MCL-1 INHIBITORS USING FRAGMENT-BASED METHODS AND STRUCTURE-BASED DESIGN | REGULATION OF APOPTOSIS, MAINTENANCE OF VIABILITY, APOPTOSIS, APOPTOSIS-INHIBITOR COMPLEX
1q59:A (ASP80) to (ASN157) SOLUTION STRUCTURE OF THE BHRF1 PROTEIN FROM EPSTEIN-BARR VIRUS, A HOMOLOG OF HUMAN BCL-2 | BHRF1, BCL-2, EPSTEIN-BARR VIRUS, NMR SPECTROSCOPY, STRUCTURE DETERMINATION, VIRAL PROTEIN
4yj4:A (THR115) to (LEU194) CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH THE BIM BH3 DOMAIN CONTAINING ILE155-TO-ARG AND GLU158-TO-PHOSPHOSERINE MUTATIONS | BCL-XL, BIM, BH3, APOPTOSIS
4zbf:A (SER247) to (PHE319) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbf:C (SER247) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbf:D (GLU240) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbf:E (SER247) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbf:F (GLU240) to (PHE318) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbf:G (SER247) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbf:I (SER247) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbf:J (SER247) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbf:K (ASN239) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
4zbf:L (GLU240) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULES | INHIBITOR, COMPLEX
3ilb:A (GLN121) to (LEU194) CRYSTAL STRUCTURE OF MOUSE BCL-XL MUTANT (R139A) AT PH 6.0 | APOPTOSIS, BH3 DOMAIN, BCL-2, MEMBRANE, MITOCHONDRION, TRANSMEMBRANE
4man:A (THR122) to (LEU198) BCL_2-NAVITOCLAX ANALOG (WITH INDOLE) COMPLEX | 8 HELICES, APOPTOSIS REGULATOR-INHIBITOR COMPLEX
1j1j:A (SER4) to (GLY124) CRYSTAL STRUCTURE OF HUMAN TRANSLIN | TESTIS/BRAIN RNA BINDING PROTEIN, SSDNA BINDING PROTEIN, RNA BINDING PROTEIN, DNA BINDING PROTEIN
1j1j:B (SER2) to (GLY124) CRYSTAL STRUCTURE OF HUMAN TRANSLIN | TESTIS/BRAIN RNA BINDING PROTEIN, SSDNA BINDING PROTEIN, RNA BINDING PROTEIN, DNA BINDING PROTEIN
1j1j:D (SER2) to (GLY124) CRYSTAL STRUCTURE OF HUMAN TRANSLIN | TESTIS/BRAIN RNA BINDING PROTEIN, SSDNA BINDING PROTEIN, RNA BINDING PROTEIN, DNA BINDING PROTEIN
3wix:A (ASN239) to (PHE319) CRYSTAL STRUCTURE OF MCL-1 IN COMPLEX WITH COMPOUND 4 | REGULATION, APOPTOSIS
3wja:A (GLN61) to (GLN122) THE CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NADP(+)-DEPENDENT MALIC ENZYME IN APO FORM | NADP(+)-BINDING ROSSMANN-FOLD DOMAINS, OXIDOREDUCTASE ACTIVITY, METAL ION BINDING, OXIDOREDUCTASE
3wja:B (GLN61) to (GLN122) THE CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NADP(+)-DEPENDENT MALIC ENZYME IN APO FORM | NADP(+)-BINDING ROSSMANN-FOLD DOMAINS, OXIDOREDUCTASE ACTIVITY, METAL ION BINDING, OXIDOREDUCTASE
1wa5:C (TYR758) to (ILE825) CRYSTAL STRUCTURE OF THE EXPORTIN CSE1P COMPLEXED WITH ITS CARGO (KAP60P) AND RANGTP | NUCLEAR TRANSPORT/COMPLEX, NUCLEAR TRANSPORT, EXPORTIN, IMPORTIN ALPHA, RAN GTPASE, PROTEIN TRANSPORT
1k3k:A (THR63) to (ARG131) SOLUTION STRUCTURE OF A BCL-2 HOMOLOG FROM KAPOSI'S SARCOMA VIRUS | BCL-2, HERPESVIRUS, SOLUTION STRUCTURE, NMR, APOPTOSIS
5c3g:A (THR118) to (TYR195) CRYSTAL STRUCTURE OF BCL-XL BOUND TO BIM-MM | COMPLEX, BCL-2 FAMILY, BH3, STAPLED PEPTIDE, APOPTOSIS
2m04:A (THR115) to (GLY196) SOLUTION STRUCTURE OF BCL-XL IN COMPLEX WITH PUMA BH3 PEPTIDE | BCL-XL, PUMA, APOPTOSIS-PROTEIN BINDING COMPLEX
4a64:A (TYR363) to (ASN450) CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN CUL4B AT 2.57A RESOLUTION | CELL CYCLE
4a64:B (TYR363) to (ASN450) CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN CUL4B AT 2.57A RESOLUTION | CELL CYCLE
4a64:C (GLU368) to (ASN450) CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN CUL4B AT 2.57A RESOLUTION | CELL CYCLE
4a64:D (TYR363) to (ASN450) CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN CUL4B AT 2.57A RESOLUTION | CELL CYCLE
1zro:A (PRO38) to (PHE147) CRYSTAL STRUCTURE OF EBA-175 REGION II (RII) CRYSTALLIZED IN THE PRESENCE OF (ALPHA)2,3-SIALYLLACTOSE | EBA-175, RII, DBL, ERYTHROCYTE, INVASION, HOST, MALARIA, DISEASE, GLYCOPHORIN, GLYCAN, SIALIC ACID, BINDING, SIALYLLACTOSE, CELL INVASION
1zro:B (PRO38) to (PHE147) CRYSTAL STRUCTURE OF EBA-175 REGION II (RII) CRYSTALLIZED IN THE PRESENCE OF (ALPHA)2,3-SIALYLLACTOSE | EBA-175, RII, DBL, ERYTHROCYTE, INVASION, HOST, MALARIA, DISEASE, GLYCOPHORIN, GLYCAN, SIALIC ACID, BINDING, SIALYLLACTOSE, CELL INVASION
1zyc:D (ILE885) to (SER978) CRYSTAL STRUCTURE OF EIF2ALPHA PROTEIN KINASE GCN2: WILD- TYPE IN APO FORM. | TRANSLATION REGULATOR, PROTEIN KINASE, SIGNAL TRANSDUCTION, AMINO-ACID STARVATION, STARVATION STRESS RESPONSE, EIF2ALPHA KINASE, TRANSFERASE
4qpe:A (ASP740) to (ALA796) CRYSTAL STRUCTURE OF AMINOPEPTIDASE N IN COMPLEX WITH N-CYCLOHEXYL-1, 2-DIAMINOETHYLPHOSPHONIC ACID | ALANINE AMINOPEPTIDASE, AMINOPEPTIDASE N, M1 FAMILY PEPTIDASES, N- CYCLOHEXYL-1,2-DIAMINOETHYLPHOSPHONIC ACID, HYDROLASE
5fdo:B (SER247) to (HIS320) MCL-1 COMPLEXED WITH SMALL MOLECULE INHIBITOR | MCL-1, INHIBITOR, APOPTOSIS-APOPTOSIS INHIBITOR COMPLEX
4c52:A (TYR120) to (LEU194) CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH BENZOYLUREA COMPOUND (39B) | APOPTOSIS
4cim:A (ALA75) to (LEU150) COMPLEX OF A BCL-W BH3 MUTANT WITH A BH3 DOMAIN | APOPTOSIS, CELL DEATH
4cim:B (ALA75) to (LEU150) COMPLEX OF A BCL-W BH3 MUTANT WITH A BH3 DOMAIN | APOPTOSIS, CELL DEATH
4s0p:A (PRO88) to (GLY166) CRYSTAL STRUCTURE OF THE AUTOINHIBITED DIMER OF PRO-APOPTOTIC BAX (II) | BCL-2 FAMILY PROTEIN, APOPTOSIS REGULATOR, AUTOINHIBITED DIMER, APOPTOSIS
4s0p:B (PRO88) to (GLY166) CRYSTAL STRUCTURE OF THE AUTOINHIBITED DIMER OF PRO-APOPTOTIC BAX (II) | BCL-2 FAMILY PROTEIN, APOPTOSIS REGULATOR, AUTOINHIBITED DIMER, APOPTOSIS
4uf1:A (THR71) to (ILE136) DEERPOX VIRUS DPV022 IN COMPLEX WITH BAK BH3 | VIRAL PROTEIN, DEERPOX VIRUS, APOPTOSIS, BCL-2, BAK BH3
4uf2:A (SER72) to (ILE136) DEERPOX VIRUS DPV022 IN COMPLEX WITH BAX BH3 | VIRAL PROTEIN, DEERPOX VIRUS, APOPTOSIS, BCL-2, BAX BH3
4ui9:N (GLN370) to (LEU442) ATOMIC STRUCTURE OF THE HUMAN ANAPHASE-PROMOTING COMPLEX | UBIQUITINATION, CELL CYCLE, APC/C, APC SUBUNITS, ANAPHASE PROMOTING COMPLEX
3pja:E (SER4) to (LEU123) CRYSTAL STRUCTURE OF HUMAN C3PO COMPLEX | 7 ALPHA HELICAL BUNDLE, RIBONUCLEASE, HYDROLASE
3pja:H (VAL3) to (LEU123) CRYSTAL STRUCTURE OF HUMAN C3PO COMPLEX | 7 ALPHA HELICAL BUNDLE, RIBONUCLEASE, HYDROLASE
5jsn:C (PHE138) to (TYR202) BCL2-INHIBITOR COMPLEX | BCL-2, ANTIBCL2, COMPLEX, VIRAL PROTEIN-INHIBITOR COMPLEX
4gf2:A (PRO177) to (LYS285) CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM ERYTHROCYTE BINDING ANTIGEN 140 (PFEBA-140/BAEBL) | PFEBA-140, BAEBL, DBL, EBL, ADHESIN, LIGAND, RECEPTOR, SIALIC ACID BINDING, GLYCOPHORIN C, CELL ADHESION, CELL INVASION