3eid:B (ASN208) to (THR303) CDK2/CYCLINA COMPLEXED WITH A PYRAZOLOPYRIDAZINE INHIBITOR | CDK2, CYCLIN, ATP-BINDING, CELL CYCLE, CELL DIVISION, KINASE, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE, NUCLEUS, TRANSFERASE-CELL CYCLE COMPLEX
3eid:D (ASN208) to (THR303) CDK2/CYCLINA COMPLEXED WITH A PYRAZOLOPYRIDAZINE INHIBITOR | CDK2, CYCLIN, ATP-BINDING, CELL CYCLE, CELL DIVISION, KINASE, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE, NUCLEUS, TRANSFERASE-CELL CYCLE COMPLEX
3ej1:B (ASN208) to (THR303) CDK2/CYCLINA COMPLEXED WITH A PYRAZOLOPYRIDAZINE INHIBITOR | CDK, CYCLIN, KINASE, ATP-BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, NUCLEUS, TRANSFERASE-CELL CYCLE COMPLEX
3ej1:D (ASN208) to (THR303) CDK2/CYCLINA COMPLEXED WITH A PYRAZOLOPYRIDAZINE INHIBITOR | CDK, CYCLIN, KINASE, ATP-BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, NUCLEUS, TRANSFERASE-CELL CYCLE COMPLEX
3eoc:B (ASN208) to (THR303) CDK2/CYCLINA COMPLEXED WITH A IMIDAZO TRIAZIN-2-AMINE | CDK, CYCLIN, ATP-BINDING, CELL CYCLE, CELL DIVISION, KINASE, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, NUCLEUS, TRANSFERASE-CELL CYCLE COMPLEX
3eoc:D (ASN208) to (THR303) CDK2/CYCLINA COMPLEXED WITH A IMIDAZO TRIAZIN-2-AMINE | CDK, CYCLIN, ATP-BINDING, CELL CYCLE, CELL DIVISION, KINASE, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, NUCLEUS, TRANSFERASE-CELL CYCLE COMPLEX
2b9r:A (GLY35) to (ASN130) CRYSTAL STRUCTURE OF HUMAN CYCLIN B1 | CYCLIN, CELL CYCLE
2b9r:B (GLY35) to (ASN130) CRYSTAL STRUCTURE OF HUMAN CYCLIN B1 | CYCLIN, CELL CYCLE
2b9r:B (PRO138) to (ASN227) CRYSTAL STRUCTURE OF HUMAN CYCLIN B1 | CYCLIN, CELL CYCLE
2bkz:B (ASN208) to (THR303) STRUCTURE OF CDK2-CYCLIN A WITH PHA-404611 | TRANSFERASE/COMPLEX, PROTEIN KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, PHOSPHORYLATION, CELL DIVISION, CYCLIN, ATP-BINDING, CELL CYCLE, MITOSIS, POLYMORPHISM
2bkz:D (ASN208) to (THR303) STRUCTURE OF CDK2-CYCLIN A WITH PHA-404611 | TRANSFERASE/COMPLEX, PROTEIN KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, PHOSPHORYLATION, CELL DIVISION, CYCLIN, ATP-BINDING, CELL CYCLE, MITOSIS, POLYMORPHISM
2bpm:B (THR207) to (THR303) STRUCTURE OF CDK2-CYCLIN A WITH PHA-630529 | PROTEIN KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, PHOSPHORYLATION, CELL DIVISION, CYCLIN
2bpm:D (ASN208) to (VAL301) STRUCTURE OF CDK2-CYCLIN A WITH PHA-630529 | PROTEIN KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, PHOSPHORYLATION, CELL DIVISION, CYCLIN
3f5x:B (ASN208) to (THR303) CDK-2-CYCLIN COMPLEX WITH INDAZOLE INHIBITOR 9 BOUND AT ITS ACTIVE SITE | KINASE, PKC, PROTEIN KINASE, INHIBITOR, ATP-BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, CYCLIN, NUCLEUS, TRANSFERASE-CELL CYCLE COMPLEX
3f5x:D (ASN208) to (THR303) CDK-2-CYCLIN COMPLEX WITH INDAZOLE INHIBITOR 9 BOUND AT ITS ACTIVE SITE | KINASE, PKC, PROTEIN KINASE, INHIBITOR, ATP-BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, CYCLIN, NUCLEUS, TRANSFERASE-CELL CYCLE COMPLEX
1bu2:A (THR48) to (LYS144) X-RAY STRUCTURE OF A VIRAL CYCLIN FROM HERPESVIRUS SAIMIRI | CELL CYCLE REGULATION, HERPESVIRUS SAIMIRI, VIRAL CYCLIN
2pk2:A (HIS154) to (PRO249) CYCLIN BOX STRUCTURE OF THE P-TEFB SUBUNIT CYCLIN T1 DERIVED FROM A FUSION COMPLEX WITH EIAV TAT | CYCLIN T1, TAT, TAR, TWINNING, TRANSCRIPTION REGULATION P- TEFB, CELL CYCLE
2pk2:B (ASP30) to (GLY145) CYCLIN BOX STRUCTURE OF THE P-TEFB SUBUNIT CYCLIN T1 DERIVED FROM A FUSION COMPLEX WITH EIAV TAT | CYCLIN T1, TAT, TAR, TWINNING, TRANSCRIPTION REGULATION P- TEFB, CELL CYCLE
2pk2:B (HIS154) to (PRO249) CYCLIN BOX STRUCTURE OF THE P-TEFB SUBUNIT CYCLIN T1 DERIVED FROM A FUSION COMPLEX WITH EIAV TAT | CYCLIN T1, TAT, TAR, TWINNING, TRANSCRIPTION REGULATION P- TEFB, CELL CYCLE
2pk2:C (ASP30) to (GLY145) CYCLIN BOX STRUCTURE OF THE P-TEFB SUBUNIT CYCLIN T1 DERIVED FROM A FUSION COMPLEX WITH EIAV TAT | CYCLIN T1, TAT, TAR, TWINNING, TRANSCRIPTION REGULATION P- TEFB, CELL CYCLE
2pk2:C (HIS154) to (THR248) CYCLIN BOX STRUCTURE OF THE P-TEFB SUBUNIT CYCLIN T1 DERIVED FROM A FUSION COMPLEX WITH EIAV TAT | CYCLIN T1, TAT, TAR, TWINNING, TRANSCRIPTION REGULATION P- TEFB, CELL CYCLE
2pk2:D (ASP30) to (GLY145) CYCLIN BOX STRUCTURE OF THE P-TEFB SUBUNIT CYCLIN T1 DERIVED FROM A FUSION COMPLEX WITH EIAV TAT | CYCLIN T1, TAT, TAR, TWINNING, TRANSCRIPTION REGULATION P- TEFB, CELL CYCLE
2pmi:B (SER76) to (VAL166) STRUCTURE OF THE PHO85-PHO80 CDK-CYCLIN COMPLEX OF THE PHOSPHATE- RESPONSIVE SIGNAL TRANSDUCTION PATHWAY WITH BOUND ATP-GAMMA-S | CYCLIN-DEPENDENT KINASE, CYCLIN, SIGNALING PROTEIN,TRANSFERASE-CELL CYCLE COMPLEX
1oi9:B (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH A 6-CYCLOHEXYLMETHYLOXY-2-ANILINO-PURINE INHIBITOR | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1oiu:B (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH A 6-CYCLOHEXYLMETHYLOXY-2-ANILINO-PURINE INHIBITOR | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1oiu:D (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH A 6-CYCLOHEXYLMETHYLOXY-2-ANILINO-PURINE INHIBITOR | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1oiy:B (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH A 6-CYCLOHEXYLMETHYLOXY-2-ANILINO-PURINE INHIBITOR | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1oiy:D (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH A 6-CYCLOHEXYLMETHYLOXY-2-ANILINO-PURINE INHIBITOR | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
4i3z:B (ASN208) to (ALA303) STRUCTURE OF PCDK2/CYCLINA BOUND TO ADP AND 2 MAGNESIUM IONS | ADP AND MAGNESIUM BINDING, T160 PHOSPHORYLATION, TRANSFERASE-CELL CYCLE COMPLEX
4i3z:D (ASN208) to (ALA303) STRUCTURE OF PCDK2/CYCLINA BOUND TO ADP AND 2 MAGNESIUM IONS | ADP AND MAGNESIUM BINDING, T160 PHOSPHORYLATION, TRANSFERASE-CELL CYCLE COMPLEX
1okw:B (ASN208) to (THR303) CYCLIN A BINDING GROOVE INHIBITOR AC-ARG-ARG-LEU-ASN-(M-CL-PHE)-NH2 | CELL CYCLE, COMPLEX(KINASE-CYCLIN), CYCLIN A, LIGAND EXCHANGE, PEPTIDOMIMETICS, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1okw:D (THR207) to (THR303) CYCLIN A BINDING GROOVE INHIBITOR AC-ARG-ARG-LEU-ASN-(M-CL-PHE)-NH2 | CELL CYCLE, COMPLEX(KINASE-CYCLIN), CYCLIN A, LIGAND EXCHANGE, PEPTIDOMIMETICS, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1okv:B (ASN208) to (THR303) CYCLIN A BINDING GROOVE INHIBITOR H-ARG-ARG-LEU-ILE-PHE-NH2 | KINASE-CYCLIN COMPLEX, CYCLIN A, INHIBITOR, LIGAND EXCHANGE, DRUG DESIGN, PEPTIDOMIMETICS, CELL CYCLE, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1okv:D (ASN208) to (THR303) CYCLIN A BINDING GROOVE INHIBITOR H-ARG-ARG-LEU-ILE-PHE-NH2 | KINASE-CYCLIN COMPLEX, CYCLIN A, INHIBITOR, LIGAND EXCHANGE, DRUG DESIGN, PEPTIDOMIMETICS, CELL CYCLE, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1ol1:B (ASN208) to (THR303) CYCLIN A BINDING GROOVE INHIBITOR H-CIT-CIT-LEU-ILE-(P-F-PHE)-NH2 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, CELL CYCLE, KINASE-CYCLIN COMPLEX, CYCLIN A, INHIBITOR, LIGAND EXCHANGE, DRUG DESIGN, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, CELL DIVISION, MITOSIS, PHOSPHORYLATION, PEPTIDOMIMETICS
1ol1:D (ASN208) to (THR303) CYCLIN A BINDING GROOVE INHIBITOR H-CIT-CIT-LEU-ILE-(P-F-PHE)-NH2 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, CELL CYCLE, KINASE-CYCLIN COMPLEX, CYCLIN A, INHIBITOR, LIGAND EXCHANGE, DRUG DESIGN, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, CELL DIVISION, MITOSIS, PHOSPHORYLATION, PEPTIDOMIMETICS
1ol2:B (ASN208) to (THR303) CYCLIN A BINDING GROOVE INHIBITOR H-ARG-ARG-LEU-ASN-(P-F-PHE)-NH2 | CELL CYCLE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, CYCLIN A, LIGAND EXCHANGE, PEPTIDOMIMETICS, KINASE
1ol2:D (ASN208) to (THR303) CYCLIN A BINDING GROOVE INHIBITOR H-ARG-ARG-LEU-ASN-(P-F-PHE)-NH2 | CELL CYCLE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, CYCLIN A, LIGAND EXCHANGE, PEPTIDOMIMETICS, KINASE
2c4g:B (ASN208) to (VAL301) STRUCTURE OF CDK2-CYCLIN A WITH PHA-533514 | PROTEIN KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, PHOSPHORYLATION, CELL DIVISION, CYCLIN, ATP-BINDING, CELL CYCLE, MITOSIS, NUCLEOTIDE-BINDING, POLYMORPHISM
2c4g:D (ASN208) to (VAL301) STRUCTURE OF CDK2-CYCLIN A WITH PHA-533514 | PROTEIN KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, PHOSPHORYLATION, CELL DIVISION, CYCLIN, ATP-BINDING, CELL CYCLE, MITOSIS, NUCLEOTIDE-BINDING, POLYMORPHISM
2c5o:B (THR207) to (THR303) DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN | DIFFERENTIAL INHIBITION, TRANSFERASE, CDK2, ATP-BINDING, CELL CYCLE, CELL DIVISION, POLYMORPHISM, PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN, KINASE, MITOSIS, CYCLIN
2c5o:D (ASN208) to (THR303) DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN | DIFFERENTIAL INHIBITION, TRANSFERASE, CDK2, ATP-BINDING, CELL CYCLE, CELL DIVISION, POLYMORPHISM, PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN, KINASE, MITOSIS, CYCLIN
2c5n:B (THR207) to (THR303) DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN | DIFFERENTIAL INHIBITION, TRANSFERASE, CDK2, ATP-BINDING, CELL CYCLE, CELL DIVISION, POLYMORPHISM, PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN, KINASE, MITOSIS, CYCLIN
2c5n:D (ASN208) to (THR303) DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN | DIFFERENTIAL INHIBITION, TRANSFERASE, CDK2, ATP-BINDING, CELL CYCLE, CELL DIVISION, POLYMORPHISM, PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN, KINASE, MITOSIS, CYCLIN
2c5v:B (THR207) to (THR303) DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN | ATP-BINDING, CELL CYCLE, CELL DIVISION, COMPLEX (KINASE/CYCLIN), CYCIN A, CYCLIN, DRUG DESIGN, LIGAND EXCHANGE, KINASE, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHORYLATION, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, COMPLEX (TRANSFERASE/CYCLIN)
2c5v:D (THR207) to (THR303) DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN | ATP-BINDING, CELL CYCLE, CELL DIVISION, COMPLEX (KINASE/CYCLIN), CYCIN A, CYCLIN, DRUG DESIGN, LIGAND EXCHANGE, KINASE, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHORYLATION, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, COMPLEX (TRANSFERASE/CYCLIN)
2c5x:B (ASN208) to (THR303) DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN | TRANSFERASE/INHIBITOR, INHIBITION, ACTIVE, INACTIVE, CDK2, CELL CYCLE, CELL DIVISION, KINASE, MITOSIS, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, ATP-BINDING, COMPLEX (TRANSFERASE/INHIBITOR)
2c5x:D (THR207) to (THR303) DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN | TRANSFERASE/INHIBITOR, INHIBITION, ACTIVE, INACTIVE, CDK2, CELL CYCLE, CELL DIVISION, KINASE, MITOSIS, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, ATP-BINDING, COMPLEX (TRANSFERASE/INHIBITOR)
2c6t:B (ASN208) to (THR303) CRYSTAL STRUCTURE OF THE HUMAN CDK2 COMPLEXED WITH THE TRIAZOLOPYRIMIDINE INHIBITOR | SERINE/THREONINE PROTEIN KINASE, CDK2, ATP-BINDING, CELL CYCLE, MITOSIS, PHOSPHORYLATION, TRIAZOLOPYRIMIDINE INHIBITOR, COMPLEX (TRANSFERASE/CYCLIN2)
2c6t:D (ASN208) to (THR303) CRYSTAL STRUCTURE OF THE HUMAN CDK2 COMPLEXED WITH THE TRIAZOLOPYRIMIDINE INHIBITOR | SERINE/THREONINE PROTEIN KINASE, CDK2, ATP-BINDING, CELL CYCLE, MITOSIS, PHOSPHORYLATION, TRIAZOLOPYRIMIDINE INHIBITOR, COMPLEX (TRANSFERASE/CYCLIN2)
2cch:B (ASN208) to (THR303) THE CRYSTAL STRUCTURE OF CDK2 CYCLIN A IN COMPLEX WITH A SUBSTRATE PEPTIDE DERIVED FROM CDC MODIFIED WITH A GAMMA- LINKED ATP ANALOGUE | COMPLEX(TRANSFERASE/CELL DIVISION), ATP-BINDING, CDK2, CELL CYCLE, CELL DIVISION, CYCLIN, MITOSIS, NUCLEAR PROTEIN, PEPTIDE SPECIFICITY, PHOSPHORYLATION, POLYMORPHISM, PROTEIN KINASE, RECRUITMENT, SERINE-THREONINE-PROTEIN KINASE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
2cch:D (ASN208) to (THR303) THE CRYSTAL STRUCTURE OF CDK2 CYCLIN A IN COMPLEX WITH A SUBSTRATE PEPTIDE DERIVED FROM CDC MODIFIED WITH A GAMMA- LINKED ATP ANALOGUE | COMPLEX(TRANSFERASE/CELL DIVISION), ATP-BINDING, CDK2, CELL CYCLE, CELL DIVISION, CYCLIN, MITOSIS, NUCLEAR PROTEIN, PEPTIDE SPECIFICITY, PHOSPHORYLATION, POLYMORPHISM, PROTEIN KINASE, RECRUITMENT, SERINE-THREONINE-PROTEIN KINASE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
2cci:B (ASN208) to (THR303) CRYSTAL STRUCTURE OF PHOSPHO-CDK2 CYCLIN A IN COMPLEX WITH A PEPTIDE CONTAINING BOTH THE SUBSTRATE AND RECRUITMENT SITES OF CDC6 | COMPLEX (TRANSFERASE/CELL DIVISION), PROTEIN KINASES, CELL CYCLE, RECRUITMENT, SUBSTRATE RECOGNITION, ATP-BINDING, CELL DIVISION, KINASE, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHORYLATION, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE, CYCLIN, DNA REPLICATION, NUCLEAR PROTEIN, COMPLEX
2cci:D (ASN208) to (THR303) CRYSTAL STRUCTURE OF PHOSPHO-CDK2 CYCLIN A IN COMPLEX WITH A PEPTIDE CONTAINING BOTH THE SUBSTRATE AND RECRUITMENT SITES OF CDC6 | COMPLEX (TRANSFERASE/CELL DIVISION), PROTEIN KINASES, CELL CYCLE, RECRUITMENT, SUBSTRATE RECOGNITION, ATP-BINDING, CELL DIVISION, KINASE, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHORYLATION, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE, CYCLIN, DNA REPLICATION, NUCLEAR PROTEIN, COMPLEX
1p5e:B (ASN208) to (THR303) THE STRUCURE OF PHOSPHO-CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR 4,5,6,7-TETRABROMOBENZOTRIAZOLE (TBS) | KINASE INHIBITOR, CDK2, TBS, CELL CYCLE
1p5e:D (ASN208) to (THR303) THE STRUCURE OF PHOSPHO-CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR 4,5,6,7-TETRABROMOBENZOTRIAZOLE (TBS) | KINASE INHIBITOR, CDK2, TBS, CELL CYCLE
2cjm:B (ASN208) to (THR303) MECHANISM OF CDK INHIBITION BY ACTIVE SITE PHOSPHORYLATION: CDK2 Y15P T160P IN COMPLEX WITH CYCLIN A STRUCTURE | PHOSPHORYLATION, NUCLEOTIDE-BINDING, MITOSIS, CELL CYCLE, REGULATION, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, TRANSFERASE, CELL DIVISION, CYCLIN-DEPENDENT KINASE, COMPLEX (TRANSFERASE/CELL DIVISION)
2cjm:D (ASN208) to (THR303) MECHANISM OF CDK INHIBITION BY ACTIVE SITE PHOSPHORYLATION: CDK2 Y15P T160P IN COMPLEX WITH CYCLIN A STRUCTURE | PHOSPHORYLATION, NUCLEOTIDE-BINDING, MITOSIS, CELL CYCLE, REGULATION, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, TRANSFERASE, CELL DIVISION, CYCLIN-DEPENDENT KINASE, COMPLEX (TRANSFERASE/CELL DIVISION)
1pkd:B (ASN208) to (THR303) THE CRYSTAL STRUCTURE OF UCN-01 IN COMPLEX WITH PHOSPHO- CDK2/CYCLIN A | PROTEIN KINASE-DRUG COMPLEX, TRANSFERASE/CELL CYCLE COMPLEX
1pkd:D (ASN208) to (THR303) THE CRYSTAL STRUCTURE OF UCN-01 IN COMPLEX WITH PHOSPHO- CDK2/CYCLIN A | PROTEIN KINASE-DRUG COMPLEX, TRANSFERASE/CELL CYCLE COMPLEX
4y72:B (THR197) to (ASN293) HUMAN CDK1/CYCLINB1/CKS2 WITH INHIBITOR | CDK1, CYCLINB1, CKS2, INHIBITOR, TRANSFERASE
4y72:B (LEU300) to (GLY392) HUMAN CDK1/CYCLINB1/CKS2 WITH INHIBITOR | CDK1, CYCLINB1, CKS2, INHIBITOR, TRANSFERASE
2r7g:C (SER644) to (LEU764) STRUCTURE OF THE RETINOBLASTOMA PROTEIN POCKET DOMAIN IN COMPLEX WITH ADENOVIRUS E1A CR1 DOMAIN | RETINOBLASTOMA PROTEIN, E1A, E2F DISPLACEMENT, TRANSCRIPTION REPRESSOR, CELL CYCLE
1e9h:B (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR INDIRUBIN-5-SULPHONATE BOUND | CELL CYCLE, COMPLEX (PROTEIN KINASE/CYCLIN), KINASES, INHIBITOR, CYCLIN, COMPLEX, PHOSPHORYLATION
1e9h:D (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR INDIRUBIN-5-SULPHONATE BOUND | CELL CYCLE, COMPLEX (PROTEIN KINASE/CYCLIN), KINASES, INHIBITOR, CYCLIN, COMPLEX, PHOSPHORYLATION
3tni:B (ASP30) to (GLY145) STRUCTURE OF CDK9/CYCLIN T F241L | CYCLIN DEPENDENT KINASE, KINASE ,CYCLIN, PHOSPHOTRANSFER, CDK-CYCLIN COMPLEX, PHOSPHORYLATED ON THREONINE 186, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3tnw:B (ASN208) to (ALA303) STRUCTURE OF CDK2/CYCLIN A IN COMPLEX WITH CAN508 | CYCLIN DEPENDENT KINASE, KINASE CYCLIN, PHOSPHOTRANSFERASE, CYCLIN A, PHOSPHORYLATION AT CDK2 THREONINE 160, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3tnw:D (ASN208) to (ALA303) STRUCTURE OF CDK2/CYCLIN A IN COMPLEX WITH CAN508 | CYCLIN DEPENDENT KINASE, KINASE CYCLIN, PHOSPHOTRANSFERASE, CYCLIN A, PHOSPHORYLATION AT CDK2 THREONINE 160, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4yc3:B (THR197) to (ASN293) CDK1/CYCLINB1/CKS2 APO | CDK1, CYCLIN B1, CKS2, CELL CYCLE
4yc3:B (LEU300) to (GLY392) CDK1/CYCLINB1/CKS2 APO | CDK1, CYCLIN B1, CKS2, CELL CYCLE
1qmz:B (ASN208) to (THR303) PHOSPHORYLATED CDK2-CYCLYIN A-SUBSTRATE PEPTIDE COMPLEX | CELL CYCLE, COMPLEX (PROTEIN KINASE/CYCLIN), CYCLIN, CDK, PHOSPHORYLATION, SUBSTRATE COMPLEX
1qmz:D (ASN208) to (THR303) PHOSPHORYLATED CDK2-CYCLYIN A-SUBSTRATE PEPTIDE COMPLEX | CELL CYCLE, COMPLEX (PROTEIN KINASE/CYCLIN), CYCLIN, CDK, PHOSPHORYLATION, SUBSTRATE COMPLEX
3h4c:A (PRO98) to (HIS188) STRUCTURE OF THE C-TERMINAL DOMAIN OF TRANSCRIPTION FACTOR IIB FROM TRYPANOSOMA BRUCEI | CYCLIN, TRANSCRIPTION FACTOR TFIIB REPEAT, TRANSCRIPTION
2uue:B (ASN208) to (THR303) REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS | POLYMORPHISM, CYCLIN GROOVE, CELL DIVISION, CDK2, KINASE, CYCLIN, ACTIVE, MITOSIS, INHIBITION, PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE, NONPEPTIDE, TRANSFERASE, ATP-BINDING
2uue:D (ASN208) to (THR303) REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS | POLYMORPHISM, CYCLIN GROOVE, CELL DIVISION, CDK2, KINASE, CYCLIN, ACTIVE, MITOSIS, INHIBITION, PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE, NONPEPTIDE, TRANSFERASE, ATP-BINDING
1f5q:B (SER46) to (SER141) CRYSTAL STRUCTURE OF MURINE GAMMA HERPESVIRUS CYCLIN COMPLEXED TO HUMAN CYCLIN DEPENDENT KINASE 2 | HERPESVIRAL CYCLIN, CYCLIN DEPENDENT KINASE. PROTEIN/PROTEIN COMPLEX, TRANSFERASE
1f5q:D (ASP66) to (SER141) CRYSTAL STRUCTURE OF MURINE GAMMA HERPESVIRUS CYCLIN COMPLEXED TO HUMAN CYCLIN DEPENDENT KINASE 2 | HERPESVIRAL CYCLIN, CYCLIN DEPENDENT KINASE. PROTEIN/PROTEIN COMPLEX, TRANSFERASE
2uzb:B (ASN208) to (THR303) CRYSTAL STRUCTURE OF HUMAN CDK2 COMPLEXED WITH A THIAZOLIDINONE INHIBITOR | TRANSFERASE, ATP-BINDING, PHOSPHORYLATION, CDK2, KINASE, CYCLIN, MITOSIS, CELL CYCLE, CELL DIVISION, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, THIAZOLIDINONE LIGAND
2uzb:D (ASN208) to (THR303) CRYSTAL STRUCTURE OF HUMAN CDK2 COMPLEXED WITH A THIAZOLIDINONE INHIBITOR | TRANSFERASE, ATP-BINDING, PHOSPHORYLATION, CDK2, KINASE, CYCLIN, MITOSIS, CELL CYCLE, CELL DIVISION, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, THIAZOLIDINONE LIGAND
2uzd:B (ASN208) to (THR303) CRYSTAL STRUCTURE OF HUMAN CDK2 COMPLEXED WITH A THIAZOLIDINONE INHIBITOR | TRANSFERASE, ATP-BINDING, PHOSPHORYLATION, CDK2, KINASE, CYCLIN, MITOSIS, CELL CYCLE, CELL DIVISION, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, THIAZOLIDINONE LIGAND
2uzd:D (ASN208) to (THR303) CRYSTAL STRUCTURE OF HUMAN CDK2 COMPLEXED WITH A THIAZOLIDINONE INHIBITOR | TRANSFERASE, ATP-BINDING, PHOSPHORYLATION, CDK2, KINASE, CYCLIN, MITOSIS, CELL CYCLE, CELL DIVISION, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, THIAZOLIDINONE LIGAND
2uze:B (ASN208) to (THR303) CRYSTAL STRUCTURE OF HUMAN CDK2 COMPLEXED WITH A THIAZOLIDINONE INHIBITOR | TRANSFERASE, ATP-BINDING, PHOSPHORYLATION, CDK2, KINASE, CYCLIN, MITOSIS, CELL CYCLE, CELL DIVISION, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, THIAZOLIDINONE LIGAND
2uze:D (ASN208) to (THR303) CRYSTAL STRUCTURE OF HUMAN CDK2 COMPLEXED WITH A THIAZOLIDINONE INHIBITOR | TRANSFERASE, ATP-BINDING, PHOSPHORYLATION, CDK2, KINASE, CYCLIN, MITOSIS, CELL CYCLE, CELL DIVISION, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, THIAZOLIDINONE LIGAND
2uzl:B (ASN208) to (THR303) CRYSTAL STRUCTURE OF HUMAN CDK2 COMPLEXED WITH A THIAZOLIDINONE INHIBITOR | TRANSFERASE, ATP-BINDING, PHOSPHORYLATION, CDK2, KINASE, CYCLIN, MITOSIS, CELL CYCLE, CELL DIVISION, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, THIAZOLIDINONE LIGAND
2uzl:D (ASN208) to (THR303) CRYSTAL STRUCTURE OF HUMAN CDK2 COMPLEXED WITH A THIAZOLIDINONE INHIBITOR | TRANSFERASE, ATP-BINDING, PHOSPHORYLATION, CDK2, KINASE, CYCLIN, MITOSIS, CELL CYCLE, CELL DIVISION, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, THIAZOLIDINONE LIGAND
2v22:B (THR207) to (THR303) REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS | POLYMORPHISM, CYCLIN GROOVE, CELL DIVISION, CDK2, KINASE, CYCLIN, ACTIVE, MITOSIS, INHIBITION, PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE, NONPEPTIDE, TRANSFERASE, ATP-BINDING
2v22:D (ASN208) to (THR303) REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS | POLYMORPHISM, CYCLIN GROOVE, CELL DIVISION, CDK2, KINASE, CYCLIN, ACTIVE, MITOSIS, INHIBITION, PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE, NONPEPTIDE, TRANSFERASE, ATP-BINDING
1fin:B (ASN208) to (THR303) CYCLIN A-CYCLIN-DEPENDENT KINASE 2 COMPLEX | COMPLEX (TRANSFERASE/CYCLIN), CYCLIN, CDK, PHOSPHORYLATION
1fin:D (ASN208) to (THR303) CYCLIN A-CYCLIN-DEPENDENT KINASE 2 COMPLEX | COMPLEX (TRANSFERASE/CYCLIN), CYCLIN, CDK, PHOSPHORYLATION
2euf:A (VAL49) to (LYS144) X-RAY STRUCTURE OF HUMAN CDK6-VCYCLIN IN COMPLEX WITH THE INHIBITOR PD0332991 | INHIBITOR COMPLEX OF HUMAN CYCLIN-DEPENDENT KINASE 6, CELL CYCLE- TRANSFERASE COMPLEX
1fvv:B (ASN208) to (THR303) THE STRUCTURE OF CDK2/CYCLIN A IN COMPLEX WITH AN OXINDOLE INHIBITOR | CYCLIN-DEPENDENT KINASE, CYCLIN A, TRANSFERASE, CELL CYCLE
1fvv:D (ASN208) to (THR303) THE STRUCTURE OF CDK2/CYCLIN A IN COMPLEX WITH AN OXINDOLE INHIBITOR | CYCLIN-DEPENDENT KINASE, CYCLIN A, TRANSFERASE, CELL CYCLE
2vj5:A (GLU82) to (ILE161) SHIGELLA FLEXNERI MXIC | SECRETION REGULATION, TRANSPORT PROTEIN, T3SS, VIRULENCE, TRANSPORT, TYPE THREE SECRETION SYSTEM
4krd:B (SER309) to (VAL406) CRYSTAL STRUCTURE OF PHO85-PCL10 COMPLEX | GLYCOGEN SYNTHESIS, CDK, CYCLIN, GLYCOGEN SYNTHESIS REGULATION, TRANSFERASE-SIGNALING PROTEIN COMPLEX
2g9x:B (THR207) to (ALA303) STRUCTURE OF THR 160 PHOSPHORYLATED CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR NU6271 | TRANSFERASE, SERINE/THREONINE PROTEIN KINASE, ATP-BINDING, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-CELL CYCLE COMPLEX
2g9x:D (ASN208) to (ALA303) STRUCTURE OF THR 160 PHOSPHORYLATED CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR NU6271 | TRANSFERASE, SERINE/THREONINE PROTEIN KINASE, ATP-BINDING, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-CELL CYCLE COMPLEX
1h1p:B (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH THE INHIBITOR NU2058 | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1h1p:D (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH THE INHIBITOR NU2058 | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1h1q:B (THR207) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH THE INHIBITOR NU6094 | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1h1q:D (MET210) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH THE INHIBITOR NU6094 | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1h1r:B (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH THE INHIBITOR NU6086 | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1h1r:D (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH THE INHIBITOR NU6086 | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1h1s:B (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH THE INHIBITOR NU6102 | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1h1s:D (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH THE INHIBITOR NU6102 | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1h24:B (ASN208) to (THR303) CDK2/CYCLIN A IN COMPLEX WITH A 9 RESIDUE RECRUITMENT PEPTIDE FROM E2F | TRANSFERASE, CELL CYCLE, PROTEIN KINASE, CYCLIN, CDK2, RECRUITMENT, PEPTIDE SPECIFICITY, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1h24:D (ASN208) to (THR303) CDK2/CYCLIN A IN COMPLEX WITH A 9 RESIDUE RECRUITMENT PEPTIDE FROM E2F | TRANSFERASE, CELL CYCLE, PROTEIN KINASE, CYCLIN, CDK2, RECRUITMENT, PEPTIDE SPECIFICITY, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1h25:B (THR207) to (THR303) CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM RETINOBLASTOMA-ASSOCIATED PROTEIN | TRANSFERASE, CELL CYCLE, PROTEIN KINASE, CYCLIN, CDK2, RECRUITMENT, PEPTIDE SPECIFICITY
1h25:D (ASN208) to (THR303) CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM RETINOBLASTOMA-ASSOCIATED PROTEIN | TRANSFERASE, CELL CYCLE, PROTEIN KINASE, CYCLIN, CDK2, RECRUITMENT, PEPTIDE SPECIFICITY
1h26:B (THR207) to (THR303) CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM P53 | CELL CYCLE, PROTEIN KINASE, CYCLIN, CDK2, RECRUITMENT, PEPTIDE SPECIFICITY
1h26:D (THR207) to (THR303) CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM P53 | CELL CYCLE, PROTEIN KINASE, CYCLIN, CDK2, RECRUITMENT, PEPTIDE SPECIFICITY
1h27:B (ASN208) to (THR303) CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM P27 | CELL CYCLE, PROTEIN KINASE, CYCLIN, CDK2, RECRUITMENT, PEPTIDE SPECIFICITY, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, CELL DIVISION, MITOSIS, PHOSPHORYLATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1h27:D (ASN208) to (THR303) CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM P27 | CELL CYCLE, PROTEIN KINASE, CYCLIN, CDK2, RECRUITMENT, PEPTIDE SPECIFICITY, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, CELL DIVISION, MITOSIS, PHOSPHORYLATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1h28:B (THR207) to (THR303) CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM P107 | CELL CYCLE, PROTEIN KINASE, CYCLIN, CDK2, RECRUITMENT, PEPTIDE SPECIFICITY, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, CELL DIVISION, MITOSIS, PHOSPHORYLATION, CELL CYCLE-TRANSFERASE SUBSTRATE, CELL CYCLE-TRANSFERASE SUBSTRATE COMPLEX
1h28:D (ASN208) to (THR303) CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM P107 | CELL CYCLE, PROTEIN KINASE, CYCLIN, CDK2, RECRUITMENT, PEPTIDE SPECIFICITY, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, CELL DIVISION, MITOSIS, PHOSPHORYLATION, CELL CYCLE-TRANSFERASE SUBSTRATE, CELL CYCLE-TRANSFERASE SUBSTRATE COMPLEX
1tfb:A (ARG112) to (ALA201) NMR STUDIES OF HUMAN GENERAL TRANSCRIPTION FACTOR TFIIB: DYNAMICS AND INTERACTION WITH VP16 ACTIVATION DOMAIN, 20 STRUCTURES | TRANSCRIPTION FACTOR, HUMAN GENERAL TRANSCRIPTION FACTOR TFIIB, C-TERMINAL CORE DOMAIN, CYCLIN BOX FOLD
2w99:A (HIS158) to (GLN263) CRYSTAL STRUCTURE OF CDK4 IN COMPLEX WITH A D-TYPE CYCLIN | SERINE/THREONINE-PROTEIN KINASE, CHROMOSOMAL REARRANGEMENT, ATP-BINDING, TRANSFERASE, POLYMORPHISM, CELL DIVISION, PROTO-ONCOGENE, PHOSPHOPROTEIN, DISEASE MUTATION, NUCLEOTIDE-BINDING, CYCLIN DEPENDENT KINASE, KINASE, CYCLIN, ONCOLOGY, CELL CYCLE, DRUG DESGN
2wev:B (ASN208) to (THR303) TRUNCATION AND OPTIMISATION OF PEPTIDE INHIBITORS OF CDK2, CYCLIN A THROUGH STRUCTURE GUIDED DESIGN | CDK2, KINASE, CYCLIN, ACTIVE, NUCLEUS, MITOSIS, SERINE/THREONINE-PROTEIN KINASE, CYTOPLASM, INHIBITION, CELL CYCLE, ATP-BINDING, CELL DIVISION, PHOSPHOPROTEIN, NUCLEOTIDE-BINDING, TRANSFERASE, POLYMORPHISM, BETA-PEPTIDE, CYCLIN GROOVE
2wev:D (ASN208) to (THR303) TRUNCATION AND OPTIMISATION OF PEPTIDE INHIBITORS OF CDK2, CYCLIN A THROUGH STRUCTURE GUIDED DESIGN | CDK2, KINASE, CYCLIN, ACTIVE, NUCLEUS, MITOSIS, SERINE/THREONINE-PROTEIN KINASE, CYTOPLASM, INHIBITION, CELL CYCLE, ATP-BINDING, CELL DIVISION, PHOSPHOPROTEIN, NUCLEOTIDE-BINDING, TRANSFERASE, POLYMORPHISM, BETA-PEPTIDE, CYCLIN GROOVE
2wfy:B (ASN208) to (THR303) TRUNCATION AND OPTIMISATION OF PEPTIDE INHIBITORS OF CDK2, CYCLIN A THROUGH STRUCTURE GUIDED DESIGN | CDK2, KINASE, CYCLIN, ACTIVE, NUCLEUS, MITOSIS, SERINE/THREONINE-PROTEIN KINASE, CYTOPLASM, INHIBITION, CELL CYCLE, ATP-BINDING, CELL DIVISION, PHOSPHOPROTEIN, NUCLEOTIDE-BINDING, TRANSFERASE, POLYMORPHISM, BETA-PEPTIDE, CYCLIN GROOVE
2wfy:D (THR207) to (THR303) TRUNCATION AND OPTIMISATION OF PEPTIDE INHIBITORS OF CDK2, CYCLIN A THROUGH STRUCTURE GUIDED DESIGN | CDK2, KINASE, CYCLIN, ACTIVE, NUCLEUS, MITOSIS, SERINE/THREONINE-PROTEIN KINASE, CYTOPLASM, INHIBITION, CELL CYCLE, ATP-BINDING, CELL DIVISION, PHOSPHOPROTEIN, NUCLEOTIDE-BINDING, TRANSFERASE, POLYMORPHISM, BETA-PEPTIDE, CYCLIN GROOVE
2whb:B (ASN208) to (LEU302) TRUNCATION AND OPTIMISATION OF PEPTIDE INHIBITORS OF CDK2, CYCLIN A THROUGH STRUCTURE GUIDED DESIGN | CDK2, KINASE, CYCLIN, ACTIVE, NUCLEUS, MITOSIS, SERINE/THREONINE-PROTEIN KINASE, CYTOPLASM, INHIBITION, CELL CYCLE, ATP-BINDING, CELL DIVISION, PHOSPHOPROTEIN, NUCLEOTIDE-BINDING, TRANSFERASE, POLYMORPHISM, BETA-PEPTIDE, CYCLIN GROOVE
2whb:D (THR207) to (THR303) TRUNCATION AND OPTIMISATION OF PEPTIDE INHIBITORS OF CDK2, CYCLIN A THROUGH STRUCTURE GUIDED DESIGN | CDK2, KINASE, CYCLIN, ACTIVE, NUCLEUS, MITOSIS, SERINE/THREONINE-PROTEIN KINASE, CYTOPLASM, INHIBITION, CELL CYCLE, ATP-BINDING, CELL DIVISION, PHOSPHOPROTEIN, NUCLEOTIDE-BINDING, TRANSFERASE, POLYMORPHISM, BETA-PEPTIDE, CYCLIN GROOVE
2wih:B (SER209) to (THR303) STRUCTURE OF CDK2-CYCLIN A WITH PHA-848125 | CELL CYCLE, ATP-BINDING, TRANSFERASE, POLYMORPHISM, PHOSPHORYLATION, NUCLEOTIDE-BINDING, CELL DIVISION, SERINE/THREONINE-PROTEIN 2 KINASE, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, MITOSIS
2wih:D (THR207) to (THR303) STRUCTURE OF CDK2-CYCLIN A WITH PHA-848125 | CELL CYCLE, ATP-BINDING, TRANSFERASE, POLYMORPHISM, PHOSPHORYLATION, NUCLEOTIDE-BINDING, CELL DIVISION, SERINE/THREONINE-PROTEIN 2 KINASE, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, MITOSIS
2wma:D (THR207) to (THR303) STRUCTURAL AND THERMODYNAMIC CONSEQUENCES OF CYCLIZATION OF PEPTIDE LIGANDS FOR THE RECRUITMENT SITE OF CYCLIN A | CELL CYCLE, CELL DIVISION, ANTI-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, PHOSPHORYLATION, NUCLEOTIDE-BINDING, TRANSCRIPTION REGULATION, CHROMATIN REGULATOR, RECRUITMENT, TRANSCRIPTION, NUCLEUS, MITOSIS, ATP-BINDING, TRANSFERASE
2wmb:B (ASN208) to (THR303) STRUCTURAL AND THERMODYNAMIC CONSEQUENCES OF CYCLIZATION OF PEPTIDE LIGANDS FOR THE RECRUITMENT SITE OF CYCLIN A | CELL CYCLE, CELL DIVISION, ANTI-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, PHOSPHORYLATION, NUCLEOTIDE-BINDING, TRANSCRIPTION REGULATION, CHROMATIN REGULATOR, RECRUITMENT, TRANSCRIPTION, NUCLEUS, MITOSIS, ATP-BINDING, TRANSFERASE
2wmb:D (ASN208) to (THR303) STRUCTURAL AND THERMODYNAMIC CONSEQUENCES OF CYCLIZATION OF PEPTIDE LIGANDS FOR THE RECRUITMENT SITE OF CYCLIN A | CELL CYCLE, CELL DIVISION, ANTI-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, PHOSPHORYLATION, NUCLEOTIDE-BINDING, TRANSCRIPTION REGULATION, CHROMATIN REGULATOR, RECRUITMENT, TRANSCRIPTION, NUCLEUS, MITOSIS, ATP-BINDING, TRANSFERASE
2i40:B (ASN208) to (THR303) CDK2/CYCLIN A COMPLEXED WITH A THIOPHENE CARBOXAMIDE INHIBITOR | CDK2, CYCLIN, KINASE, TRANSFERASE-CELL CYCLE COMPLEX
2i40:D (ASN208) to (THR303) CDK2/CYCLIN A COMPLEXED WITH A THIOPHENE CARBOXAMIDE INHIBITOR | CDK2, CYCLIN, KINASE, TRANSFERASE-CELL CYCLE COMPLEX
2i53:A (ASP42) to (GLY133) CRYSTAL STRUCTURE OF CYCLIN K | CELL CYCLE, TRANSCRIPTION, CYCLIN K, CYCLIN BOX, CDK9, POSITIVE TRANSCRIPTION ELONGATION FACTOR, P-TEFB
2i53:A (PRO160) to (ILE254) CRYSTAL STRUCTURE OF CYCLIN K | CELL CYCLE, TRANSCRIPTION, CYCLIN K, CYCLIN BOX, CDK9, POSITIVE TRANSCRIPTION ELONGATION FACTOR, P-TEFB
2wxv:B (ASN208) to (THR303) STRUCTURE OF CDK2-CYCLIN A WITH A PYRAZOLO(4,3-H) QUINAZOLINE-3-CARBOXAMIDE INHIBITOR | NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE, TRANSFERASE, KINASE, CYCLIN
2wxv:D (ASN208) to (THR303) STRUCTURE OF CDK2-CYCLIN A WITH A PYRAZOLO(4,3-H) QUINAZOLINE-3-CARBOXAMIDE INHIBITOR | NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE, TRANSFERASE, KINASE, CYCLIN
1urc:B (THR207) to (THR303) CYCLIN A BINDING GROOVE INHIBITOR ACE-ARG-LYS-LEU-PHE-GLY | TRANSFERASE-INHIBITOR COMPLEX, INHIBITOR, LIGAND EXCHANGE, DRUG DESIGN, PEPTIDOMIMETICS
1urc:D (ASN208) to (THR303) CYCLIN A BINDING GROOVE INHIBITOR ACE-ARG-LYS-LEU-PHE-GLY | TRANSFERASE-INHIBITOR COMPLEX, INHIBITOR, LIGAND EXCHANGE, DRUG DESIGN, PEPTIDOMIMETICS
5acb:A (PRO43) to (LYS152) CRYSTAL STRUCTURE OF THE HUMAN CDK12-CYCLINK COMPLEX | TRANSFERASE
5acb:B (PRO43) to (LYS152) CRYSTAL STRUCTURE OF THE HUMAN CDK12-CYCLINK COMPLEX | TRANSFERASE
5acb:B (PRO160) to (SER259) CRYSTAL STRUCTURE OF THE HUMAN CDK12-CYCLINK COMPLEX | TRANSFERASE
2ivx:A (GLU29) to (GLY144) CRYSTAL STRUCTURE OF HUMAN CYCLIN T2 AT 1.8 A RESOLUTION (CASP TARGET) | TRANSCRIPTION REGULATION, CELL DIVISION, PHOSPHORYLATION, NUCLEAR PROTEIN, CYCLIN, CELL CYCLE, TRANSCRIPTION
2ivx:B (GLU29) to (GLY144) CRYSTAL STRUCTURE OF HUMAN CYCLIN T2 AT 1.8 A RESOLUTION (CASP TARGET) | TRANSCRIPTION REGULATION, CELL DIVISION, PHOSPHORYLATION, NUCLEAR PROTEIN, CYCLIN, CELL CYCLE, TRANSCRIPTION
2iw6:B (THR207) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A COMPLEXED WITH A BISANILINOPYRIMIDINE INHIBITOR | PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE COMPLEX, KINASE, MITOSIS, CELL CYCLE, TRANSFERASE, ATP-BINDING
2iw6:D (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A COMPLEXED WITH A BISANILINOPYRIMIDINE INHIBITOR | PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE COMPLEX, KINASE, MITOSIS, CELL CYCLE, TRANSFERASE, ATP-BINDING
2iw8:B (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A F82H-L83V- H84D MUTANT WITH AN O6-CYCLOHEXYLMETHYLGUANINE INHIBITOR | PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE COMPLEX, KINASE, MITOSIS, CELL CYCLE, TRANSFERASE
2iw8:D (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A F82H-L83V- H84D MUTANT WITH AN O6-CYCLOHEXYLMETHYLGUANINE INHIBITOR | PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE COMPLEX, KINASE, MITOSIS, CELL CYCLE, TRANSFERASE
2iw9:B (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A COMPLEXED WITH A BISANILINOPYRIMIDINE INHIBITOR | PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE COMPLEX, KINASE, MITOSIS, CELL CYCLE, TRANSFERASE
2iw9:D (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A COMPLEXED WITH A BISANILINOPYRIMIDINE INHIBITOR | PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE COMPLEX, KINASE, MITOSIS, CELL CYCLE, TRANSFERASE
1jkw:A (GLU49) to (ASN155) STRUCTURE OF CYCLIN MCS2 | CYCLIN, CELL CYCLE, CELL DIVISION, NUCLEAR PROTEIN
1vin:A (ASN208) to (ALA303) BOVINE CYCLIN A3 | CYCLIN, CELL CYCLE, KINASE-REGULATORY-SUBUNIT, BINDING PROTEIN
1jow:A (THR48) to (LYS144) CRYSTAL STRUCTURE OF A COMPLEX OF HUMAN CDK6 AND A VIRAL CYCLIN | CDK-CYCLIN COMPLEX, CYCLIN FOLD, CELL CYCLE/TRANSFERASE COMPLEX
1jst:B (ASN208) to (THR303) PHOSPHORYLATED CYCLIN-DEPENDENT KINASE-2 BOUND TO CYCLIN A | COMPLEX (PROTEIN KINASE-CYCLIN), CYCLIN, CDK, PHOSPHORYLATION, COMPLEX (PROTEIN KINASE-CYCLIN) COMPLEX
1jst:D (THR207) to (THR303) PHOSPHORYLATED CYCLIN-DEPENDENT KINASE-2 BOUND TO CYCLIN A | COMPLEX (PROTEIN KINASE-CYCLIN), CYCLIN, CDK, PHOSPHORYLATION, COMPLEX (PROTEIN KINASE-CYCLIN) COMPLEX
1jsu:B (THR207) to (VAL301) P27(KIP1)/CYCLIN A/CDK2 COMPLEX | COMPLEX (TRANSFERASE/CYCLIN/INHIBITOR), KINASE, CELL CYCLE, CELL DIVISION, CDK, CYCLIN, INHIBITOR
1vyw:B (ASN208) to (THR303) STRUCTURE OF CDK2/CYCLIN A WITH PNU-292137 | TRANSFERASE/COMPLEX, PROTEIN KINASE/COMPLEX, PROTEIN KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, PHOSPHORYLATION, CELL DIVISION, CYCLIN
1vyw:D (ASN208) to (THR303) STRUCTURE OF CDK2/CYCLIN A WITH PNU-292137 | TRANSFERASE/COMPLEX, PROTEIN KINASE/COMPLEX, PROTEIN KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, PHOSPHORYLATION, CELL DIVISION, CYCLIN
5bnj:B (SER33) to (ASP147) CDK8/CYCC IN COMPLEX WITH 8-{3-CHLORO-5-[4-(1-METHYL-1H-PYRAZOL-4-YL)- PHENYL]-PYRIDIN- 4-YL}-2,8-DIAZA-SPIRO[4.5]DECAN-1-ONE | CDK8 KINASE / CYCLIN C, TRANSFERASE
5bnj:B (TYR156) to (ASN243) CDK8/CYCC IN COMPLEX WITH 8-{3-CHLORO-5-[4-(1-METHYL-1H-PYRAZOL-4-YL)- PHENYL]-PYRIDIN- 4-YL}-2,8-DIAZA-SPIRO[4.5]DECAN-1-ONE | CDK8 KINASE / CYCLIN C, TRANSFERASE
1w98:B (LYS128) to (LYS223) THE STRUCTURAL BASIS OF CDK2 ACTIVATION BY CYCLIN E | CELL CYCLE, TRANSFERASE
4nst:B (PRO43) to (LYS152) CRYSTAL STRUCTURE OF HUMAN CDK12/CYCLIN K IN COMPLEX WITH ADP-ALUMINUM FLUORIDE | TRANSCRIPTION, RNA POLYMERASE II, PHOSPHORYLATION, TRANSFERASE- TRANSCRIPTION COMPLEX
4nst:D (PRO43) to (LYS152) CRYSTAL STRUCTURE OF HUMAN CDK12/CYCLIN K IN COMPLEX WITH ADP-ALUMINUM FLUORIDE | TRANSCRIPTION, RNA POLYMERASE II, PHOSPHORYLATION, TRANSFERASE- TRANSCRIPTION COMPLEX
1kxu:A (GLU49) to (ASN155) CYCLIN H, A POSITIVE REGULATORY SUBUNIT OF CDK ACTIVATING KINASE | REGULATORY PROTEIN, CYCLIN, CELL CYCLE, CELL DIVISION, NUCLEAR PROTEIN, ALPHA-HELICAL STRUCTURE
5cei:B (SER33) to (ASP147) CRYSTAL STRUCTURE OF CDK8:CYCLIN C COMPLEX WITH COMPOUND 22 | KINASE, INHIBITOR, CDK8, CYCLIN DEPENDENT KINASE, CYCLIN, TRANSCRIPTION-TRANSFERASE-INHIBITOR COMPLEX
5cei:B (TYR156) to (ASN243) CRYSTAL STRUCTURE OF CDK8:CYCLIN C COMPLEX WITH COMPOUND 22 | KINASE, INHIBITOR, CDK8, CYCLIN DEPENDENT KINASE, CYCLIN, TRANSCRIPTION-TRANSFERASE-INHIBITOR COMPLEX
4ogr:B (ASP30) to (GLY145) CRYSTAL STRUCTURE OF P-TEFB COMPLEX WITH AFF4 AND TAT | P-TEFB, CYCLIN-DEPENDENT KINASE 9, CYCLIN FOLD, INTRINSICALLY UNSTRUCTURED AFF4, TRANSCRIPTIONAL REGULATION AT HIV PROMOTER, BINDS TAR, N-TERMINAL ACETYLATION OF TAT, TRANSFERASE-VIRAL PROTEIN COMPLEX
4ogr:F (ASP30) to (GLY145) CRYSTAL STRUCTURE OF P-TEFB COMPLEX WITH AFF4 AND TAT | P-TEFB, CYCLIN-DEPENDENT KINASE 9, CYCLIN FOLD, INTRINSICALLY UNSTRUCTURED AFF4, TRANSCRIPTIONAL REGULATION AT HIV PROMOTER, BINDS TAR, N-TERMINAL ACETYLATION OF TAT, TRANSFERASE-VIRAL PROTEIN COMPLEX
4or5:B (ASP30) to (GLY145) CRYSTAL STRUCTURE OF HIV-1 TAT COMPLEXED WITH HUMAN P-TEFB AND AFF4 | CDK9, TAT, AFF4, ZINC FINGER, TRANSCRIPTION, RNA BINDING, PHOSPHORYLATION, TRANSFERASE-TRANSCRIPTION COMPLEX
4or5:G (PRO153) to (THR248) CRYSTAL STRUCTURE OF HIV-1 TAT COMPLEXED WITH HUMAN P-TEFB AND AFF4 | CDK9, TAT, AFF4, ZINC FINGER, TRANSCRIPTION, RNA BINDING, PHOSPHORYLATION, TRANSFERASE-TRANSCRIPTION COMPLEX
5cyi:B (ASN208) to (THR303) CDK2/CYCLIN A COVALENT COMPLEX WITH 6-(CYCLOHEXYLMETHOXY)-N-(4- (VINYLSULFONYL)PHENYL)-9H-PURIN-2-AMINE (NU6300) | CDK2 CYCLIN A COVALENT INHIBITOR VINYLSULPHONE, TRANSFERASE
5cyi:D (ASN208) to (THR303) CDK2/CYCLIN A COVALENT COMPLEX WITH 6-(CYCLOHEXYLMETHOXY)-N-(4- (VINYLSULFONYL)PHENYL)-9H-PURIN-2-AMINE (NU6300) | CDK2 CYCLIN A COVALENT INHIBITOR VINYLSULPHONE, TRANSFERASE
1zp2:A (SER29) to (ASP130) STRUCTURE OF THE MEDIATOR SUBUNIT CYCLIN C | CYCLIN REPEAT DOMAINS, TRANSCRIPTION-CELL CYCLE COMPLEX
3lq5:B (ASP30) to (GLY145) STRUCTURE OF CDK9/CYCLINT IN COMPLEX WITH S-CR8 | TRANSCRIPTIONAL CDK-CYCLIN COMPLEX, PHOSPHORYLATED, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION REGULATION, TRANSFERASE, CELL CYCLE, CELL DIVISION, HOST-VIRUS INTERACTION,, TRANSCRIPTION-INHIBITOR COMPLEX
5efq:B (PRO43) to (GLY133) CRYSTAL STRUCTURE OF HUMAN CDK13/CYCLIN K IN COMPLEX WITH ADP-ALUMINUM FLUORIDE | KINASE, CYCLIN, ADP, TRANSFERASE
5efq:B (PRO160) to (ASP256) CRYSTAL STRUCTURE OF HUMAN CDK13/CYCLIN K IN COMPLEX WITH ADP-ALUMINUM FLUORIDE | KINASE, CYCLIN, ADP, TRANSFERASE
5efq:D (ASP42) to (LYS152) CRYSTAL STRUCTURE OF HUMAN CDK13/CYCLIN K IN COMPLEX WITH ADP-ALUMINUM FLUORIDE | KINASE, CYCLIN, ADP, TRANSFERASE
4bbr:M (LYS121) to (ILE213) STRUCTURE OF RNA POLYMERASE II-TFIIB COMPLEX | TRANSCRIPTION, RNA POLYMERASE, TFIIB
4bbs:M (GLU125) to (ILE213) STRUCTURE OF AN INITIALLY TRANSCRIBING RNA POLYMERASE II- TFIIB COMPLEX | TRANSCRIPTION
4bcg:B (ASP30) to (GLY145) STRUCTURE OF CDK9 IN COMPLEX WITH CYCLIN T AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, TRANSCRIPTION-PROTEIN BINDING, STRUCTURE-BASED DRUG DESIGN
4bcj:B (ASP30) to (GLY145) STRUCTURE OF CDK9 IN COMPLEX WITH CYCLIN T AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, TRANSCRIPTION-PROTEIN BINDING, STRUCTURE-BASED DRUG DESIGN
4bck:B (THR207) to (VAL301) STRUCTURE OF CDK2 IN COMPLEX WITH CYCLIN A AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, STRUCTURE-BASED DRUG DESIGN
4bck:D (ASN208) to (THR303) STRUCTURE OF CDK2 IN COMPLEX WITH CYCLIN A AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, STRUCTURE-BASED DRUG DESIGN
4bcn:B (ASN208) to (THR303) STRUCTURE OF CDK2 IN COMPLEX WITH CYCLIN A AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, CYCLIN-INHIBITOR, STRUCTURE-BASED DRUG DESIGN
4bcn:D (ASN208) to (THR303) STRUCTURE OF CDK2 IN COMPLEX WITH CYCLIN A AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, CYCLIN-INHIBITOR, STRUCTURE-BASED DRUG DESIGN
4bcp:B (ASN208) to (THR303) STRUCTURE OF CDK2 IN COMPLEX WITH CYCLIN A AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, CYCLIN-INHIBITOR, STRUCTURE-BASED DRUG DESIGN
4bcp:D (ASN208) to (THR303) STRUCTURE OF CDK2 IN COMPLEX WITH CYCLIN A AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, CYCLIN-INHIBITOR, STRUCTURE-BASED DRUG DESIGN
4bcq:D (ASN208) to (THR303) STRUCTURE OF CDK2 IN COMPLEX WITH CYCLIN A AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, CYCLIN A, CYCLIN- DEPENDENT KINASE 2, STRUCTURE-BASED DRUG DESIGN
3mi9:B (ASP30) to (GLY145) CRYSTAL STRUCTURE OF HIV-1 TAT COMPLEXED WITH HUMAN P-TEFB | P-TEFB, TAT, HIV-1, PROTEIN BINDING
3bht:B (ASN208) to (ALA303) STRUCTURE OF PHOSPHORYLATED THR160 CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR MERIOLIN 3 | SER/THR PROTEIN KINASE, TRANSFERASE, PHOSPHORYLATION, CELL CYCLE, ATP-BINDING, CELL DIVISION, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, CYCLIN
3bht:D (ASN208) to (ALA303) STRUCTURE OF PHOSPHORYLATED THR160 CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR MERIOLIN 3 | SER/THR PROTEIN KINASE, TRANSFERASE, PHOSPHORYLATION, CELL CYCLE, ATP-BINDING, CELL DIVISION, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, CYCLIN
3blh:B (ASP30) to (GLY145) CRYSTAL STRUCTURE OF HUMAN CDK9/CYCLINT1 | TRANSCRIPTIONAL CDK/CYCLIN COMPLEX, PHOSPHORYLATED, ALTERNATIVE SPLICING, ATP-BINDING, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION REGULATION, TRANSFERASE, ACETYLATION, CELL CYCLE, CELL DIVISION, COILED COIL, HOST-VIRUS INTERACTION
3my1:B (ASP30) to (GLY145) STRUCTURE OF CDK9/CYCLINT1 IN COMPLEX WITH DRB | CDK-CYCLIN COMPLEX, PHOSPHORYLATED, TRANSCRIPTION-PROTEIN BINDING- INHIBITOR COMPLEX
3my5:B (ASN208) to (ALA303) CDK2/CYCLINA IN COMPLEX WITH DRB | CDK, CYCLIN, INHIBITOR, DRB, TRANSFERASE-PROTEIN BINDING-INHIBITOR COMPLEX
3my5:D (ASN208) to (ALA303) CDK2/CYCLINA IN COMPLEX WITH DRB | CDK, CYCLIN, INHIBITOR, DRB, TRANSFERASE-PROTEIN BINDING-INHIBITOR COMPLEX
5fgk:B (SER33) to (ASP147) CDK8-CYCC IN COMPLEX WITH 8-[3-(3-AMINO-1H-INDAZOL-6-YL)-5-CHLORO- PYRIDINE-4-YL]-2,8-DIAZA-SPIRO[4.5]DECAN-1-ONE | CDK8 KINASE / CYCLIN C, TRANSFERASE
5fgk:B (PRO158) to (ASN243) CDK8-CYCC IN COMPLEX WITH 8-[3-(3-AMINO-1H-INDAZOL-6-YL)-5-CHLORO- PYRIDINE-4-YL]-2,8-DIAZA-SPIRO[4.5]DECAN-1-ONE | CDK8 KINASE / CYCLIN C, TRANSFERASE
4rod:A (SER66) to (GLY161) HUMAN TFIIB-RELATED FACTOR 2 (BRF2) AND TBP BOUND TO TRNAU1 PROMOTER | TRANSCRIPTION FACTOR, TRANSCRIPTION
4roe:A (SER66) to (GLY161) HUMAN TFIIB-RELATED FACTOR 2 (BRF2) AND TBP BOUND TO RPPH1 PROMOTER | TRANSCRIPTION FACTOR, TRANSCRIPTION
4cfm:B (ASN208) to (THR303) STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6- CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS. | CELL CYCLE, CYCLIN DEPENDENT KINASES, STRUCTURE-BASED DRUG DESIGN, CONFORMATIONAL RESTRAINT, REVERSED BINDING MODE
4cfm:D (THR207) to (THR303) STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6- CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS. | CELL CYCLE, CYCLIN DEPENDENT KINASES, STRUCTURE-BASED DRUG DESIGN, CONFORMATIONAL RESTRAINT, REVERSED BINDING MODE
4cfn:B (ASN208) to (THR303) STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6-CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS. | CELL CYCLE, CYCLIN DEPENDENT KINASES, STRUCTURE-BASED DRUG DESIGN, CONFORMATIONAL RESTRAINT, REVERSED BINDING MODE
4cfn:D (ASN208) to (THR303) STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6-CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS. | CELL CYCLE, CYCLIN DEPENDENT KINASES, STRUCTURE-BASED DRUG DESIGN, CONFORMATIONAL RESTRAINT, REVERSED BINDING MODE
4cfv:B (ASN208) to (THR303) STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6- CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS. | TRANSFERASE, CYCLIN DEPENDENT KINASES, STRUCTURE-BASED DRUG DESIGN, CONFORMATIONAL RESTRAINT, REVERSED BINDING MODE
4cfv:D (ASN208) to (THR303) STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6- CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS. | TRANSFERASE, CYCLIN DEPENDENT KINASES, STRUCTURE-BASED DRUG DESIGN, CONFORMATIONAL RESTRAINT, REVERSED BINDING MODE
4cfw:B (ASN208) to (THR303) STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6- CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS. | CELL CYCLE, STRUCTURE-BASED DRUG DESIGN, CONFORMATIONAL RESTRAINT, REVERSED BINDING MODE
4cfw:D (ASN208) to (THR303) STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6- CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS. | CELL CYCLE, STRUCTURE-BASED DRUG DESIGN, CONFORMATIONAL RESTRAINT, REVERSED BINDING MODE
4cfx:B (ASN208) to (LEU302) STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6-CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS. | CELL CYCLE, STRUCTURE-BASED DRUG DESIGN, CONFORMATIONAL RESTRAINT, REVERSED BINDING MODE
4cfx:D (ASN208) to (THR303) STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6-CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS. | CELL CYCLE, STRUCTURE-BASED DRUG DESIGN, CONFORMATIONAL RESTRAINT, REVERSED BINDING MODE
4crl:B (TYR156) to (ASN243) CRYSTAL STRUCTURE OF HUMAN CDK8-CYCLIN C IN COMPLEX WITH CORTISTATIN A | TRANSFERASE, CYCLIN-DEPENDENT KINASE 8, CDK8, CYCLIN C, CCNC, CORTISTATIN A, MEDIATOR KINASE, MEDIATOR COMPLEX, SUPER-ENHANCER, TRANSCRIPTION
4cxa:B (ASP42) to (GLY133) CRYSTAL STRUCTURE OF THE HUMAN CDK12-CYCLIN K COMPLEX BOUND TO AMPPNP | TRANSFERASE, KINASE
4cxa:D (ASP42) to (LYS152) CRYSTAL STRUCTURE OF THE HUMAN CDK12-CYCLIN K COMPLEX BOUND TO AMPPNP | TRANSFERASE, KINASE
4tth:A (THR48) to (LYS144) CRYSTAL STRUCTURE OF A CDK6/VCYCLIN COMPLEX WITH INHIBITOR BOUND | KINASE, TRANSFERASE-CELL CYCLE-INHIBITOR COMPLEX
3dog:B (ASN208) to (ALA303) STRUCTURE OF THR 160 PHOSPHORYLATED CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR N-&-N1 | SER/THR PROTEIN KINASE; TRANSFERASE; PHOSPHORYLATION; CELL CYCLE, ATP-BINDING, CELL CYCLE, CELL DIVISION, KINASE, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, CYCLIN, CYTOPLASM, NUCLEUS
3dog:D (ASN208) to (ALA303) STRUCTURE OF THR 160 PHOSPHORYLATED CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR N-&-N1 | SER/THR PROTEIN KINASE; TRANSFERASE; PHOSPHORYLATION; CELL CYCLE, ATP-BINDING, CELL CYCLE, CELL DIVISION, KINASE, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, CYCLIN, CYTOPLASM, NUCLEUS
5hbe:B (TYR156) to (ASN243) CDK8-CYCC IN COMPLEX WITH 8-[3-CHLORO-5-(1-METHYL-2,2-DIOXO-2, 3- DIHYDRO-1H-2L6-BENZO[C]ISOTHIAZOL-5-YL)-PYRIDIN- 4-YL]-1-OXA-3,8- DIAZA-SPIRO[4.5]DECAN-2-ONE | CDK8 KINASE / CYCLIN C, TRANSFERASE
5hbh:B (SER33) to (ASP147) CDK8-CYCC IN COMPLEX WITH 5-{5-CHLORO-4-[1-(2-METHOXY-ETHYL)-1,8- DIAZA-SPIRO[4.5]DEC-8-YL]-PYRIDIN-3-YL}-1-METHYL-1,3-DIHYDRO- BENZO[C]ISOTHIAZOLE 2,2-DIOXIDE | CDK8 KINASE / CYCLIN C, TRANSFERASE
5hnb:B (SER33) to (ASP147) CDK8-CYCC IN COMPLEX WITH [6-HYDROXY-3-(3-METHYL-BENZYL)-1H-INDAZOL-5- YL]-((S)-3-HYDROXY-PYRROLIDIN-1-YL)-METHANONE | CDK8 KINASE / CYCLIN C, TRANSFERASE
5hnb:B (TYR156) to (ASN243) CDK8-CYCC IN COMPLEX WITH [6-HYDROXY-3-(3-METHYL-BENZYL)-1H-INDAZOL-5- YL]-((S)-3-HYDROXY-PYRROLIDIN-1-YL)-METHANONE | CDK8 KINASE / CYCLIN C, TRANSFERASE
5hq0:B (THR197) to (ASN293) TERNARY COMPLEX OF HUMAN PROTEINS CDK1, CYCLIN B AND CKS2, BOUND TO AN INHIBITOR | CDK1, CYCLIN B, CKS2, CELL-CYCLE, PROTEIN KINASE, INHIBITOR, TRANSFERASE
5hq0:B (LEU300) to (GLY392) TERNARY COMPLEX OF HUMAN PROTEINS CDK1, CYCLIN B AND CKS2, BOUND TO AN INHIBITOR | CDK1, CYCLIN B, CKS2, CELL-CYCLE, PROTEIN KINASE, INHIBITOR, TRANSFERASE
5hvy:B (SER33) to (MET146) CDK8/CYCC IN COMPLEX WITH COMPOUND 20 | TRANSFERASE-TRANSCRIPTION COMPLEX
5hvy:B (TYR156) to (ASN243) CDK8/CYCC IN COMPLEX WITH COMPOUND 20 | TRANSFERASE-TRANSCRIPTION COMPLEX
4un0:A (ASP42) to (GLY133) CRYSTAL STRUCTURE OF THE HUMAN CDK12-CYCLINK COMPLEX | TRANSFERASE
4un0:B (ASP42) to (LYS152) CRYSTAL STRUCTURE OF THE HUMAN CDK12-CYCLINK COMPLEX | TRANSFERASE
5i5z:B (SER33) to (ASP147) CDK8-CYCC IN COMPLEX WITH 8-(1-METHYL-2,2-DIOXO-2,3-DIHYDRO-1H-2L6- BENZO[C]ISOTHIAZOL-5-YL)-[1,6]NAPHTHYRIDINE-2-CARBOXYLIC ACID METHYLAMIDE | CDK8 KINASE / CYCLIN C, TRANSFERASE
5i5z:B (TYR156) to (ASN243) CDK8-CYCC IN COMPLEX WITH 8-(1-METHYL-2,2-DIOXO-2,3-DIHYDRO-1H-2L6- BENZO[C]ISOTHIAZOL-5-YL)-[1,6]NAPHTHYRIDINE-2-CARBOXYLIC ACID METHYLAMIDE | CDK8 KINASE / CYCLIN C, TRANSFERASE
3pom:A (SER644) to (SER758) CRYSTAL STRUCTURE OF THE UNLIGANDED RETINOBLASTOMA PROTEIN POCKET DOMAIN | CYCLIN FOLD, TUMOR SUPPRESSOR PROTEIN, CELL CYCLE
3pom:B (THR645) to (SER758) CRYSTAL STRUCTURE OF THE UNLIGANDED RETINOBLASTOMA PROTEIN POCKET DOMAIN | CYCLIN FOLD, TUMOR SUPPRESSOR PROTEIN, CELL CYCLE
5if1:B (ASN208) to (THR303) CRYSTAL STRUCTURE APO CDK2/CYCLIN A | ANTINEOPLASTIC AGENTS, CYCLIN-DEPENDENT KINASES, DOSE-RESPONSE RELATIONSHIP, DRUG, DRUG DISCOVERY, HELA CELLS, MOLECULAR STRUCTURE, NEOPLASMS, PROTEIN KINASE INHIBITORS, PYRIMIDINES, STRUCTURE- ACTIVITY RELATIONSHIP, STRUCTURE-KINETICS RELATIONSHIP, SULFOXIDES, BIOPHYSICAL ASSAYS, TUMOR, HUMANS, TRANSFERASE
5if1:D (ASN208) to (VAL301) CRYSTAL STRUCTURE APO CDK2/CYCLIN A | ANTINEOPLASTIC AGENTS, CYCLIN-DEPENDENT KINASES, DOSE-RESPONSE RELATIONSHIP, DRUG, DRUG DISCOVERY, HELA CELLS, MOLECULAR STRUCTURE, NEOPLASMS, PROTEIN KINASE INHIBITORS, PYRIMIDINES, STRUCTURE- ACTIVITY RELATIONSHIP, STRUCTURE-KINETICS RELATIONSHIP, SULFOXIDES, BIOPHYSICAL ASSAYS, TUMOR, HUMANS, TRANSFERASE
4ec8:B (ASP30) to (GLY145) STRUCTURE OF FULL LENGTH CDK9 IN COMPLEX WITH CYCLINT AND DRB | CYCLIN DEPENDEND KINASE, CYCLIN, TRANSFERASE-PROTEIN BINDING COMPLEX
4ec9:B (ASP30) to (GLY145) CRYSTAL STRUCTURE OF FULL-LENGTH CDK9 IN COMPLEX WITH CYCLIN T | CYCLIN DEPENDENT KINASE, CYCLIN, KINASE, PHOSPHORYLATION, NUCLEAR, TRANSFERASE-PROTEIN BINDING COMPLEX
4elj:A (PRO55) to (ILE138) CRYSTAL STRUCTURE OF THE INACTIVE RETINOBLASTOMA PROTEIN PHOSPHORYLATED AT T373 | CYCLIN FOLD, TUMOR SUPPRESSOR PROTEIN, PHOSPHORYLATION, CELL CYCLE
4eoi:B (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 K89D, Q131E - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR RO3306 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eoi:D (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 K89D, Q131E - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR RO3306 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eoj:B (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 H84S, Q85M, K89D - HUMAN CYCLIN A3 COMPLEX WITH ATP | PROTEIN KINASE, CELL CYCLE, COMPLEX, PHOSPHORYLATION, TRANSFERASE
4eoj:D (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 H84S, Q85M, K89D - HUMAN CYCLIN A3 COMPLEX WITH ATP | PROTEIN KINASE, CELL CYCLE, COMPLEX, PHOSPHORYLATION, TRANSFERASE
4eok:B (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 H84S, Q85M, K89D - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR NU6102 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eok:D (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 H84S, Q85M, K89D - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR NU6102 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eok:D (THR310) to (LYS400) THR 160 PHOSPHORYLATED CDK2 H84S, Q85M, K89D - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR NU6102 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eol:B (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 H84S, Q85M, K89D - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR RO3306 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eol:D (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 H84S, Q85M, K89D - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR RO3306 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eom:B (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 H84S, Q85M, Q131E - HUMAN CYCLIN A3 COMPLEX WITH ATP | PROTEIN KINASE, CELL CYCLE, COMPLEX, PHOSPHORYLATION, TRANSFERASE
4eom:D (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 H84S, Q85M, Q131E - HUMAN CYCLIN A3 COMPLEX WITH ATP | PROTEIN KINASE, CELL CYCLE, COMPLEX, PHOSPHORYLATION, TRANSFERASE
4eon:B (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 H84S, Q85M, Q131E - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR RO3306 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eon:D (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 H84S, Q85M, Q131E - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR RO3306 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eoo:B (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 Q131E - HUMAN CYCLIN A3 COMPLEX WITH ATP | PROTEIN KINASE, CELL CYCLE, COMPLEX, PHOSPHORYLATION, TRANSFERASE
4eoo:D (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 Q131E - HUMAN CYCLIN A3 COMPLEX WITH ATP | PROTEIN KINASE, CELL CYCLE, COMPLEX, PHOSPHORYLATION, TRANSFERASE
4eop:B (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 Q131E - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR RO3306 | PROTEIN KINASE, CELL CYCLE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eop:D (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 Q131E - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR RO3306 | PROTEIN KINASE, CELL CYCLE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eoq:B (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 WT - HUMAN CYCLIN A3 COMPLEX WITH ATP | PROTEIN KINASE, CELL CYCLE, COMPLEX, PHOSPHORYLATION, TRANSFERASE
4eoq:D (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 WT - HUMAN CYCLIN A3 COMPLEX WITH ATP | PROTEIN KINASE, CELL CYCLE, COMPLEX, PHOSPHORYLATION, TRANSFERASE
4eor:B (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 WT - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR NU6102 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eor:D (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 WT - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR NU6102 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eos:B (THR207) to (THR303) THR 160 PHOSPHORYLATED CDK2 WT - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR RO3306 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eos:D (ASN208) to (THR303) THR 160 PHOSPHORYLATED CDK2 WT - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR RO3306 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5iy6:M (THR211) to (ILE292) HUMAN HOLO-PIC IN THE CLOSED STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
5iy7:M (ALA113) to (GLU203) HUMAN HOLO-PIC IN THE OPEN STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
5iy7:M (THR211) to (ILE292) HUMAN HOLO-PIC IN THE OPEN STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
5iy8:M (SER108) to (GLU203) HUMAN HOLO-PIC IN THE INITIAL TRANSCRIBING STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
5iy9:M (THR211) to (ILE292) HUMAN HOLO-PIC IN THE INITIAL TRANSCRIBING STATE (NO IIS) | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA- RNA COMPLEX
5iyb:M (ALA113) to (GLU203) HUMAN CORE-PIC IN THE OPEN STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
5iyb:M (THR211) to (ILE292) HUMAN CORE-PIC IN THE OPEN STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
5iyd:M (THR211) to (ILE292) HUMAN CORE-PIC IN THE INITIAL TRANSCRIBING STATE (NO IIS) | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA- RNA COMPLEX
3qhr:B (ASN208) to (ALA303) STRUCTURE OF A PCDK2/CYCLINA TRANSITION-STATE MIMIC | KINASE CATALYTIC DOMAIN, PROTEIN KINASE, CYCLIN, PHOSPHORYLATED THR- 160, TRANSFERASE-PROTEIN BINDING COMPLEX
3qhr:D (ASN208) to (ALA303) STRUCTURE OF A PCDK2/CYCLINA TRANSITION-STATE MIMIC | KINASE CATALYTIC DOMAIN, PROTEIN KINASE, CYCLIN, PHOSPHORYLATED THR- 160, TRANSFERASE-PROTEIN BINDING COMPLEX
3qhw:B (ASN208) to (ALA303) STRUCTURE OF A PCDK2/CYCLINA TRANSITION-STATE MIMIC | KINASE CATALYTIC DOMAIN, PROTEIN KINASE, CYCLIN, PHOSPHORYLATED THR- 160, PHOSPHORYLATED ON THR-160, TRANSFERASE-PROTEIN BINDING COMPLEX
3qhw:D (ASN208) to (ALA303) STRUCTURE OF A PCDK2/CYCLINA TRANSITION-STATE MIMIC | KINASE CATALYTIC DOMAIN, PROTEIN KINASE, CYCLIN, PHOSPHORYLATED THR- 160, PHOSPHORYLATED ON THR-160, TRANSFERASE-PROTEIN BINDING COMPLEX
4f6s:B (SER33) to (ASP147) CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN COMPLEX WITH COMPOUND 7 (1-[3- TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]UREA) | PROTEIN KINASE COMPLEX, PROTEROS, TRANSFERASE-TRANSCRIPTION-INHIBITOR COMPLEX
4f6s:B (TYR156) to (ASN243) CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN COMPLEX WITH COMPOUND 7 (1-[3- TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]UREA) | PROTEIN KINASE COMPLEX, PROTEROS, TRANSFERASE-TRANSCRIPTION-INHIBITOR COMPLEX
4f6u:B (TYR156) to (ASN243) CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN COMPLEX WITH COMPOUND 5 (1-[3- TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-[3-(MORPHOLIN-4-YL) PROPYL]UREA) | PROTEIN KINASE COMPLEX, PROTEROS, TRANSFERASE-TRANSCRIPTION-INHIBITOR COMPLEX
4f6w:B (TYR156) to (ASN243) CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN COMPLEX WITH COMPOUND 1 (N-[3- TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-4-[2-({[3-TERT-BUTYL- 1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]CARBAMOYL}AMINO)ETHYL]PIPERAZINE- 1-CARBOXAMIDE) | PROTEIN KINASE COMPLEX, PROTEROS, TRANSFERASE-TRANSCRIPTION-INHIBITOR COMPLEX
4f7j:B (TYR156) to (ASN243) CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN COMPLEX WITH COMPOUND 3 (1-[3- TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-(2-HYDROXYETHYL) UREA) | PROTEIN KINASE COMPLEX, PROTEROS, TRANSFERASE-TRANSCRIPTION-INHIBITOR COMPLEX
4f7l:B (PRO155) to (ASN243) CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN COMPLEX WITH COMPOUND 2 (TERT- BUTYL [3-({[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5- YL]CARBAMOYL}AMINO)PROPYL]CARBAMATE) | PROTEIN KINASE COMPLEX, PROTEROS, TRANSFERASE-TRANSCRIPTION-INHIBITOR COMPLEX
4f7n:B (TYR156) to (ASN243) CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN COMPLEX WITH COMPOUND 11 (1- [3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-(5- HYDROXYPENTYL)UREA) | PROTEIN KINASE COMPLEX, PROTEROS, TRANSFERASE-TRANSCRIPTION-INHIBITOR COMPLEX
3rgf:B (SER33) to (ASP147) CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC | PROTEIN KINASE COMPLEX, TRANSFERASE,TRANSCRIPTION
3rgf:B (TYR156) to (ASN243) CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC | PROTEIN KINASE COMPLEX, TRANSFERASE,TRANSCRIPTION
5l1z:B (ASP30) to (GLY145) TAR COMPLEX WITH HIV-1 TAT-AFF4-P-TEFB | HIV-1 TAR, PROTEIN-RNA COMPLEX, TRANSCRIPTION, PROTEIN KINASE, TRANSCRIPTION-RNA COMPLEX
5l2w:B (LYS128) to (LYS223) THE X-RAY CO-CRYSTAL STRUCTURE OF HUMAN CDK2/CYCLINE AND DINACICLIB. | CYCLIN-DEPENDENT KINASE, KINASE INHIBITOR, KINASE SELECTIVITY, TRANSFERASE-CELL CYCLE-INHIBITOR COMPLEX
1o9k:B (SER644) to (LEU764) CRYSTAL STRUCTURE OF THE RETINOBLASTOMA TUMOUR SUPPRESSOR PROTEIN BOUND TO E2F PEPTIDE | APOPTOSIS, TUMOUR SUPPRESSOR, CELL CYCLE REGULATION, DNA-BINDING
1o9k:F (SER646) to (SER758) CRYSTAL STRUCTURE OF THE RETINOBLASTOMA TUMOUR SUPPRESSOR PROTEIN BOUND TO E2F PEPTIDE | APOPTOSIS, TUMOUR SUPPRESSOR, CELL CYCLE REGULATION, DNA-BINDING
1ogu:B (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH A 2-ARYLAMINO-4-CYCLOHEXYLMETHYL-5-NITROSO-6-AMINOPYRIMIDINE INHIBITOR | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
1ogu:D (ASN208) to (THR303) STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH A 2-ARYLAMINO-4-CYCLOHEXYLMETHYL-5-NITROSO-6-AMINOPYRIMIDINE INHIBITOR | KINASE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP- BINDING, CELL CYCLE, CELL DIVISION, MITOSIS, PHOSPHORYLATION
4ii5:B (ASN208) to (ALA303) STRUCTURE OF PCDK2/CYCLINA BOUND TO ADP AND 1 MAGNESIUM ION | ADP AND MAGNESIUM BINDING, T160 PHOSPHORYLATION, TRANSFERASE-CELL CYCLE COMPLEX
4ii5:D (ASN208) to (ALA303) STRUCTURE OF PCDK2/CYCLINA BOUND TO ADP AND 1 MAGNESIUM ION | ADP AND MAGNESIUM BINDING, T160 PHOSPHORYLATION, TRANSFERASE-CELL CYCLE COMPLEX
2qdj:A (PRO55) to (ASP139) CRYSTAL STRUCTURE OF THE RETINOBLASTOMA PROTEIN N-DOMAIN PROVIDES INSIGHT INTO TUMOR SUPPRESSION, LIGAND INTERACTION AND HOLOPROTEIN ARCHITECTURE | CYCLIN FOLD, CYCLIN WEDGE, ANTITUMOR PROTEIN
2f2c:A (THR48) to (LYS144) X-RAY STRUCTURE OF HUMAN CDK6-VCYCLINWITH THE INHIBITOR AMINOPURVALANOL | SMALL MOLECULE INHIBITOR BOUND BETWEEN N-TERMINAL AND C-TERMINAL DOMAIN OF KINASE, CELL CYCLE-TRANSFERASE COMPLEX
1gh6:B (ALA658) to (LYS765) RETINOBLASTOMA POCKET COMPLEXED WITH SV40 LARGE T ANTIGEN | TUMOR SUPPRESSOR, ONCOPROTEIN, ANTITUMOR PROTEIN
1gux:B (THR645) to (SER758) RB POCKET BOUND TO E7 LXCXE MOTIF | COMPLEX (TRANSCRIPTION REGULATION/PEPTIDE), TUMOR SUPPRESSOR PROTEIN, RETINOBLASTOMA, COMPLEX (TRANSCRIPTION REG/PEPTIDE) COMPLEX
1gy3:B (ASN208) to (THR303) PCDK2/CYCLIN A IN COMPLEX WITH MGADP, NITRATE AND PEPTIDE SUBSTRATE | TRANSFERASE-TRANSFERASE SUBSTRATE COMPLEX, CELL CYCLE REGULATORY PROTEIN KINASE, THR160-PHOSPHO-CYCLIN DEPENDENT PROTEIN KINASE 2 IN ASSOCIATION WITH CYCLIN A, TRANSFERASE- TRANSFERASE SUBSTRATE COMPLEX
1gy3:D (ASN208) to (THR303) PCDK2/CYCLIN A IN COMPLEX WITH MGADP, NITRATE AND PEPTIDE SUBSTRATE | TRANSFERASE-TRANSFERASE SUBSTRATE COMPLEX, CELL CYCLE REGULATORY PROTEIN KINASE, THR160-PHOSPHO-CYCLIN DEPENDENT PROTEIN KINASE 2 IN ASSOCIATION WITH CYCLIN A, TRANSFERASE- TRANSFERASE SUBSTRATE COMPLEX
2w2h:A (ASP30) to (GLY145) STRUCTURAL BASIS OF TRANSCRIPTION ACTIVATION BY THE CYCLIN T1-TAT-TAR RNA COMPLEX FROM EIAV | RNA-BINDING PROTEIN, TAR, TAT, CYCLIN, NUCLEUS, ACTIVATOR, CYCLIN T1, HOST-VIRUS INTERACTION, TRANSCRIPTION REGULATION, CELL CYCLE, RNA-BINDING, ACETYLATION, COILED COIL, TRANSCRIPTION, CELL DIVISION, CRYSTALLIZATION
2w2h:A (PRO153) to (LYS247) STRUCTURAL BASIS OF TRANSCRIPTION ACTIVATION BY THE CYCLIN T1-TAT-TAR RNA COMPLEX FROM EIAV | RNA-BINDING PROTEIN, TAR, TAT, CYCLIN, NUCLEUS, ACTIVATOR, CYCLIN T1, HOST-VIRUS INTERACTION, TRANSCRIPTION REGULATION, CELL CYCLE, RNA-BINDING, ACETYLATION, COILED COIL, TRANSCRIPTION, CELL DIVISION, CRYSTALLIZATION
2w2h:B (ASP30) to (GLY145) STRUCTURAL BASIS OF TRANSCRIPTION ACTIVATION BY THE CYCLIN T1-TAT-TAR RNA COMPLEX FROM EIAV | RNA-BINDING PROTEIN, TAR, TAT, CYCLIN, NUCLEUS, ACTIVATOR, CYCLIN T1, HOST-VIRUS INTERACTION, TRANSCRIPTION REGULATION, CELL CYCLE, RNA-BINDING, ACETYLATION, COILED COIL, TRANSCRIPTION, CELL DIVISION, CRYSTALLIZATION
2w2h:B (PRO153) to (LYS247) STRUCTURAL BASIS OF TRANSCRIPTION ACTIVATION BY THE CYCLIN T1-TAT-TAR RNA COMPLEX FROM EIAV | RNA-BINDING PROTEIN, TAR, TAT, CYCLIN, NUCLEUS, ACTIVATOR, CYCLIN T1, HOST-VIRUS INTERACTION, TRANSCRIPTION REGULATION, CELL CYCLE, RNA-BINDING, ACETYLATION, COILED COIL, TRANSCRIPTION, CELL DIVISION, CRYSTALLIZATION
2wip:B (ASN208) to (THR303) STRUCTURE OF CDK2-CYCLIN A COMPLEXED WITH 8-ANILINO-1- METHYL-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H] QUINAZOLINE-3- CARBOXYLIC ACID | CELL CYCLE, ATP-BINDING, TRANSFERASE, POLYMORPHISM, PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN 2 KINASE, SERINE/THREONINE-PROTEIN KINASE, CELL DIVISION, PHOSPHOPROTEIN, PROTEIN KINASE, KINASE, CYCLIN, NUCLEUS, MITOSIS, CYTOPLASM
2wip:D (ASN208) to (THR303) STRUCTURE OF CDK2-CYCLIN A COMPLEXED WITH 8-ANILINO-1- METHYL-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H] QUINAZOLINE-3- CARBOXYLIC ACID | CELL CYCLE, ATP-BINDING, TRANSFERASE, POLYMORPHISM, PHOSPHORYLATION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN 2 KINASE, SERINE/THREONINE-PROTEIN KINASE, CELL DIVISION, PHOSPHOPROTEIN, PROTEIN KINASE, KINASE, CYCLIN, NUCLEUS, MITOSIS, CYTOPLASM
2wpa:B (ASN208) to (THR303) OPTIMISATION OF 6,6-DIMETHYL PYRROLO 3,4-C PYRAZOLES: IDENTIFICATION OF PHA-793887, A POTENT CDK INHIBITOR SUITABLE FOR INTRAVENOUS DOSING | SERINE/THREONINE-PROTEIN 2 KINASE, CYCLIN, MITOSIS, CELL CYCLE, TRANSFERASE, ATP-BINDING, PHOSPHOPROTEIN,
2wpa:D (ASN208) to (LEU302) OPTIMISATION OF 6,6-DIMETHYL PYRROLO 3,4-C PYRAZOLES: IDENTIFICATION OF PHA-793887, A POTENT CDK INHIBITOR SUITABLE FOR INTRAVENOUS DOSING | SERINE/THREONINE-PROTEIN 2 KINASE, CYCLIN, MITOSIS, CELL CYCLE, TRANSFERASE, ATP-BINDING, PHOSPHOPROTEIN,
2x1n:B (THR207) to (THR303) TRUNCATION AND OPTIMISATION OF PEPTIDE INHIBITORS OF CDK2, CYCLIN A THROUGH STRUCTURE GUIDED DESIGN | INHIBITION, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE, CELL DIVISION
2x1n:D (ASN208) to (THR303) TRUNCATION AND OPTIMISATION OF PEPTIDE INHIBITORS OF CDK2, CYCLIN A THROUGH STRUCTURE GUIDED DESIGN | INHIBITION, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE, CELL DIVISION
1n4m:B (SER644) to (SER758) STRUCTURE OF RB TUMOR SUPPRESSOR BOUND TO THE TRANSACTIVATION DOMAIN OF E2F-2 | PROTEIN-PEPTIDE COMPLEX, CELL CYCLE
4bcf:B (ASP30) to (GLY145) STRUCTURE OF CDK9 IN COMPLEX WITH CYCLIN T AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, TRANSCRIPTION-PROTEIN BINDING, STRUCTURE-BASED DRUG DESIGN
4bch:B (ASP30) to (GLY145) STRUCTURE OF CDK9 IN COMPLEX WITH CYCLIN T AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, TRANSCRIPTION-PROTEIN BINDING, STRUCTURE-BASED DRUG DESIGN
4bcm:B (ASN208) to (THR303) STRUCTURE OF CDK2 IN COMPLEX WITH CYCLIN A AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, STRUCTURE-BASED DRUG DESIGN
4bcm:D (THR207) to (THR303) STRUCTURE OF CDK2 IN COMPLEX WITH CYCLIN A AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, STRUCTURE-BASED DRUG DESIGN
4bco:B (ASN208) to (THR303) STRUCTURE OF CDK2 IN COMPLEX WITH CYCLIN A AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, CYCLIN-INHIBITOR, STRUCTURE-BASED DRUG DESIGN
4bco:D (ASN208) to (THR303) STRUCTURE OF CDK2 IN COMPLEX WITH CYCLIN A AND A 2-AMINO-4- HETEROARYL-PYRIMIDINE INHIBITOR | TRANSFERASE-CELL CYCLE COMPLEX, CDK-CYCLIN COMPLEX, CYCLIN-INHIBITOR, STRUCTURE-BASED DRUG DESIGN
3bhu:B (ASN208) to (ALA303) STRUCTURE OF PHOSPHORYLATED THR160 CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR MERIOLIN 5 | SER/THR PROTEIN KINASE, TRANSFERASE, PHOSPHORYLATION, CELL CYCLE, ATP-BINDING, CELL DIVISION, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, CYCLIN
3bhu:D (ASN208) to (ALA303) STRUCTURE OF PHOSPHORYLATED THR160 CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR MERIOLIN 5 | SER/THR PROTEIN KINASE, TRANSFERASE, PHOSPHORYLATION, CELL CYCLE, ATP-BINDING, CELL DIVISION, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, CYCLIN
3bhv:B (ASN208) to (ALA303) STRUCTURE OF PHOSPHORYLATED THR160 CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR VARIOLIN B | SER/THR PROTEIN KINASE, TRANSFERASE, PHOSPHORYLATION, CELL CYCLE, ATP-BINDING, CELL DIVISION, MITOSIS, NUCLEOTIDE- BINDING, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE- PROTEIN KINASE, CYCLIN
3bhv:D (ASN208) to (ALA303) STRUCTURE OF PHOSPHORYLATED THR160 CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR VARIOLIN B | SER/THR PROTEIN KINASE, TRANSFERASE, PHOSPHORYLATION, CELL CYCLE, ATP-BINDING, CELL DIVISION, MITOSIS, NUCLEOTIDE- BINDING, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE- PROTEIN KINASE, CYCLIN
4cfu:B (ASN208) to (ALA303) STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6- CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS. | TRANSFERASE, STRUCTURE-BASED DRUG DESIGN, CONFORMATIONAL RESTRAINT, REVERSED BINDING MODE
4cfu:D (ASN208) to (ALA303) STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6- CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS. | TRANSFERASE, STRUCTURE-BASED DRUG DESIGN, CONFORMATIONAL RESTRAINT, REVERSED BINDING MODE
3ddp:B (ASN208) to (ALA303) STRUCTURE OF PHOSPHORYLATED THR160 CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR CR8 | SER/THR PROTEIN KINASE; PHOSPHORYLATION; CELL CYCLE, ATP- BINDING, CELL DIVISION, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, CYCLIN, CYTOPLASM, NUCLEUS, TRANSFERASE/CELL CYCLE COMPLEX
3ddp:D (ASN208) to (ALA303) STRUCTURE OF PHOSPHORYLATED THR160 CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR CR8 | SER/THR PROTEIN KINASE; PHOSPHORYLATION; CELL CYCLE, ATP- BINDING, CELL DIVISION, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, CYCLIN, CYTOPLASM, NUCLEUS, TRANSFERASE/CELL CYCLE COMPLEX
3ddq:B (ASN208) to (ALA303) STRUCTURE OF PHOSPHORYLATED THR160 CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR ROSCOVITINE | SER/THR PROTEIN KINASE; TRANSFERASE; PHOSPHORYLATION; CELL CYCLE, ATP-BINDING, CELL CYCLE, CELL DIVISION, KINASE, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, CYCLIN, CYTOPLASM, NUCLEUS, TRANSFERASE/CELL CYCLE COMPLEX
3ddq:D (ASN208) to (ALA303) STRUCTURE OF PHOSPHORYLATED THR160 CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR ROSCOVITINE | SER/THR PROTEIN KINASE; TRANSFERASE; PHOSPHORYLATION; CELL CYCLE, ATP-BINDING, CELL CYCLE, CELL DIVISION, KINASE, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, CYCLIN, CYTOPLASM, NUCLEUS, TRANSFERASE/CELL CYCLE COMPLEX
5hbj:B (TYR156) to (ASN243) CDK8-CYCC IN COMPLEX WITH 8-[2-AMINO-3-CHLORO-5-(1-METHYL-1H-INDAZOL- 5-YL)-PYRIDIN-4-YL]-2,8-DIAZA-SPIRO[4.5]DECAN-1-ONE | CDK8 KINASE / CYCLIN C, TRANSFERASE
4ell:A (SER644) to (LEU764) STRUCTURE OF THE INACTIVE RETINOBLASTOMA PROTEIN POCKET DOMAIN | CYCLIN FOLD, TUMOR SUPPRESSOR, CELL CYCLE
5iya:M (THR211) to (ILE292) HUMAN CORE-PIC IN THE CLOSED STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
5iyc:M (SER108) to (GLU203) HUMAN CORE-PIC IN THE INITIAL TRANSCRIBING STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
4f7s:B (SER33) to (ASP147) CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN THE DMG-IN CONFORMATION | PROTEIN KINASE COMPLEX, PROTEROS, TRANSFERASE-TRANSCRIPTION-INHIBITOR COMPLEX
4f7s:B (TYR156) to (ASN243) CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN THE DMG-IN CONFORMATION | PROTEIN KINASE COMPLEX, PROTEROS, TRANSFERASE-TRANSCRIPTION-INHIBITOR COMPLEX
4fx3:B (ASN208) to (THR303) CRYSTAL STRUCTURE OF THE CDK2/CYCLIN A COMPLEX WITH OXINDOLE INHIBITOR | COMPLEX (TRANSFERASE-CYCLIN), TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4fx3:D (ASN208) to (THR303) CRYSTAL STRUCTURE OF THE CDK2/CYCLIN A COMPLEX WITH OXINDOLE INHIBITOR | COMPLEX (TRANSFERASE-CYCLIN), TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4g6l:B (SER33) to (ASP147) CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN THE DMG-IN CONFORMATION | PROTEIN KINASE COMPLEX, PROTEROS, TRANSFERASE-TRANSCRIPTION COMPLEX
4g6l:B (TYR156) to (ASN243) CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN THE DMG-IN CONFORMATION | PROTEIN KINASE COMPLEX, PROTEROS, TRANSFERASE-TRANSCRIPTION COMPLEX