2o8m:B (GLU32) to (SER66) CRYSTAL STRUCTURE OF THE S139A MUTANT OF HEPATITIS C VIRUS NS3/4A PROTEASE | SERINE PROTEASE, NS3, NS4A, HEPATITIS C VIRUS, VIRAL PROTEIN
3e5r:C (ILE173) to (LYS253) CRYSTAL STRUCTURE AND FUNCTIONAL ANALYSIS OF GLYCERALDEHYDE- 3-PHOSPHATE DEHYDROGENASE FROM ORYZA SATIVA | GAPDH, GLYCERALDEHYDE-3-PHOSPHATE, ORYZA SATIVA, RICE, OXIDOREDUCTASE, CYTOPLASM, GLYCOLYSIS, NAD
2aho:B (ILE16) to (ILE65) STRUCTURE OF THE ARCHAEAL INITIATION FACTOR EIF2 ALPHA- GAMMA HETERODIMER FROM SULFOLOBUS SOLFATARICUS COMPLEXED WITH GDPNP | INITIATION OF TRANSLATION
1a0l:D (GLN30) to (LEU68) HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE | TRYPSIN-LIKE SERINE PROTEINASE, TETRAMER, HEPARIN, ALLERGY, ASTHMA, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1n8o:B (GLN30) to (GLY69) CRYSTAL STRUCTURE OF A COMPLEX BETWEEN BOVINE CHYMOTRYPSIN AND ECOTIN | HYDROLASE
1a1r:A (GLU58) to (SER92) HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX | VIRAL PROTEIN, SERINE PROTEASE, NONSTRUCTURAL PROTEINS, COFACTOR PEPTIDE, HELICASE
2oc8:C (GLU32) to (SER66) STRUCTURE OF HEPATITIS C VIRAL NS3 PROTEASE DOMAIN COMPLEXED WITH NS4A PEPTIDE AND KETOAMIDE SCH503034 | HEPATITIS C VIRUS, HCV, NS3 PROTEASE DOMAIN, KETOAMIDE INHIBITOR, VIRAL PROTEIN
2odp:A (TRP460) to (GLY503) COMPLEMENT COMPONENT C2A, THE CATALYTIC FRAGMENT OF C3- AND C5- CONVERTASE OF HUMAN COMPLEMENT | COMPLEMENT COMPONENT C2A, C3/C5 CONVERTASE, COMPLEMENT SERINE PROTEASE, HUMAN COMPLEMENT SYSTEM, GLYCOPROTEIN, SP, VWFA, HYDROLASE
1nbm:B (GLU51) to (ARG90) THE STRUCTURE OF BOVINE F1-ATPASE COVALENTLY INHIBITED WITH 4-CHLORO-7-NITROBENZOFURAZAN | ATP SYNTHASE, F1FO ATP SYNTHASE, F1-ATPASE, 4-CHLORO-7- NITROBENZOFURAZAN, INHIBITION
3ea8:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE TRIPLE MUTANT STI/A IN SPACE GROUP C2 | SARS CORONAVIRUS MAIN PROTEASE 3C-LIKE PROTEASE MUTANT EXTRA HELICAL DOMAIN, CYTOPLASM, HYDROLASE, MEMBRANE, METAL- BINDING, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
3ea9:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE QUADRUPLE MUTANT STIF/A WITH ONE MOLECULE IN ONE ASYMMETRIC UNIT | SARS CORONAVIRUS MAIN PROTEASE MUTANT, 3C-LIKE PROTEASE, EXTRA HELICAL DOMAIN, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA- BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
3eaj:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE QUADRUPLE MUTANT STIF/A WITH TWO MOLECULES IN ONE ASYMMETRIC UNIT | SARS CORONAVIRUS MAIN PROTEASE MUTANT EXTRA HELICAL DOMAIN, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
2alp:A (ILE31) to (ILE66) REFINED STRUCTURE OF ALPHA-LYTIC PROTEASE AT 1.7 ANGSTROMS RESOLUTION. ANALYSIS OF HYDROGEN BONDING AND SOLVENT STRUCTURE | HYDROLASE (SERINE PROTEINASE)
3rn1:F (LYS149) to (THR187) CRYSTAL STRUCTURE OF THE W199E-MAUG/PRE-METHYLAMINE DEHYDROGENASE COMPLEX | MAUG, METHYLAMINE DEHYDROGENASE, C-HEME, QUINONE COFACTOR, ELECTRON TRANSPORT, OXIDOREDUCTASE-ELECTRON TRANSPORT COMPLEX
1acc:A (ASN268) to (ASN368) ANTHRAX PROTECTIVE ANTIGEN | TOXIN, CALCIUM-BINDING
4wmd:B (ALA113) to (GLY157) CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE MERS-COV 3CL PROTEASE (C148A) IN SPACEGROUP C2221 | 3CL PROTEASE, MERS, CORONAVIRUS, HYDROLASE
2op9:A (GLY109) to (TYR154) SUBSTRATE SPECIFICITY PROFILING AND IDENTIFICATION OF A NEW CLASS OF INHIBITOR FOR THE MAJOR PROTEASE OF THE SARS CORONAVIRUS | SARS, 3CLPRO, PROTEINASE, PROTEASE, HYDROLASE
3s17:B (SER1155) to (HIS1195) RNA POLYMERASE II INITIATION COMPLEX WITH A 9-NT RNA | RNA POLYMERASE II, INITIATION COMPLEX, TRANSCRIPTION-RNA-DNA HYBRID COMPLEX, TRANSCRIPTION-RNA-DNA COMPLEX
1az4:A (LYS104) to (ILE192) ECORV ENDONUCLEASE, UNLIGANDED, FORM B, T93A MUTANT | ENDONUCLEASE
4wt4:B (SER303) to (LEU347) THE C-TERMINAL DOMAIN OF RUBISCO ACCUMULATION FACTOR 1 FROM ARABIDOPSIS THALIANA, CRYSTAL FORM I | CHAPERONE
2p3e:A (HIS327) to (LEU372) CRYSTAL STRUCTURE OF AQ1208 FROM AQUIFEX AEOLICUS | AQ1208, AQUIFEX AEOLICUS, SOUTHEAST COLLABORATORY FOR STRUCTURAL GENOMICS, RIKEN SPRING-8 CENTER, RIKEN GENOMIC SCIENCES CENTER, DEPARTMENT OF BIOLOGICAL SCIENCES OSAKA UNIVERSITY, DEPARTMENT OF BIOPHYSICS AND BIOCHEMISTRY UNIVERSITY OF TOKYO, PSI, PROTEIN STRUCTURE INITIATIVE, SECSG, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LYASE
2bdg:A (TRP29) to (GLY69) HUMAN KALLIKREIN 4 COMPLEX WITH NICKEL AND P-AMINOBENZAMIDINE | SERINE PROTEINASE, S1 SUBSITE, 70-80 LOOP, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, STRUCTURAL GENOMICS, HYDROLASE
2bdg:B (GLN30) to (GLY69) HUMAN KALLIKREIN 4 COMPLEX WITH NICKEL AND P-AMINOBENZAMIDINE | SERINE PROTEINASE, S1 SUBSITE, 70-80 LOOP, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, STRUCTURAL GENOMICS, HYDROLASE
2p59:A (GLU58) to (SER92) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS3.4A PROTEASE | HCV PROTEASE, VIRAL PROTEIN
4wxi:A (GLN30) to (GLY69) FACTOR XIA IN COMPLEX WITH THE INHIBITOR TRANS-N-{(1S)-1-[4-(3-AMINO- 2H-INDAZOL-6-YL)PYRIDIN-2-YL]-2-PHENYLETHYL}-4-(AMINOMETHYL) CYCLOHEXANECARBOXAMIDE | HYDROLASE, SERINE PROTEASE, BLOOD COAGULATION FACTOR, PROTEIN INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4wy3:A (GLY109) to (TYR154) STRUCTURE OF SARS-3CL PROTEASE COMPLEX WITH A PHENYLBENZOYL (R,S)-N- DECALIN TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
2ber:A (GLU584) to (SER628) Y370G ACTIVE SITE MUTANT OF THE SIALIDASE FROM MICROMONOSPORA VIRIDIFACIENS IN COMPLEX WITH BETA-NEU5AC (SIALIC ACID). | GLYCOSIDASE, HYDROLASE, SIALIDASE, BETA-PROPELLER, MICROMONOSPORA VIRIDIFACIENS
2bhg:B (ASN15) to (ASP58) 3C PROTEASE FROM TYPE A10(61) FOOT-AND-MOUTH DISEASE VIRUS | FOOT-AND-MOUTH DISEASE VIRUS, PROTEASE, CHYMOTRYPSIN-LIKE CYSTEINE PROTEASE, CAPSID PROTEIN, CORE PROTEIN, COVALENT PROTEIN-RNA LINKAGE, HYDROLASE, LIPOPROTEIN, MYRISTATE, POLYPROTEIN, RNA-DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE
4hi3:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF DIMERIC R298A MUTANT OF SARS CORONAVIRUS MAIN PROTEASE | CHYMOTRYPSIN-LIKE PROTEIN, PROTEASE, CYTOSOL, HYDROLASE
4hi3:B (GLY109) to (TYR154) CRYSTAL STRUCTURE OF DIMERIC R298A MUTANT OF SARS CORONAVIRUS MAIN PROTEASE | CHYMOTRYPSIN-LIKE PROTEIN, PROTEASE, CYTOSOL, HYDROLASE
3s2k:A (LEU936) to (ALA969) STRUCTURAL BASIS OF WNT SIGNALING INHIBITION BY DICKKOPF BINDING TO LRP5/6. | WNT CO-RECEPTOR, BETA-PROPELLER, EGF DOMAIN, WNT SIGNALING, WNT INHIBITOR, GLYCOSYLATION, SIGNALING PROTEIN
3s2k:B (PHE633) to (ALA666) STRUCTURAL BASIS OF WNT SIGNALING INHIBITION BY DICKKOPF BINDING TO LRP5/6. | WNT CO-RECEPTOR, BETA-PROPELLER, EGF DOMAIN, WNT SIGNALING, WNT INHIBITOR, GLYCOSYLATION, SIGNALING PROTEIN
4x1w:A (GLY510) to (SER548) CRYSTAL STRUCTURE OF UNBOUND RHDVB P DOMAIN | MAJOR CAPSID PROTEIN, CAPSID SPIKE, PROTRUDING DOMAIN, DIMER, HBGA BINDING, VIRAL PROTEIN
4x1w:C (GLY510) to (SER548) CRYSTAL STRUCTURE OF UNBOUND RHDVB P DOMAIN | MAJOR CAPSID PROTEIN, CAPSID SPIKE, PROTRUDING DOMAIN, DIMER, HBGA BINDING, VIRAL PROTEIN
2bm2:A (GLN30) to (LEU68) HUMAN BETA-II TRYPTASE IN COMPLEX WITH 4-(3-AMINOMETHYL- PHENYL)-PIPERIDIN-1-YL-(5-PHENETHYL- PYRIDIN-3-YL)- METHANONE | SERINE PROTEASE INHIBITOR, GLYCOPROTEIN, HYDROLASE, POLYMORPHISM, PROTEASE, SERINE PROTEASE
2bm2:C (GLN30) to (LEU68) HUMAN BETA-II TRYPTASE IN COMPLEX WITH 4-(3-AMINOMETHYL- PHENYL)-PIPERIDIN-1-YL-(5-PHENETHYL- PYRIDIN-3-YL)- METHANONE | SERINE PROTEASE INHIBITOR, GLYCOPROTEIN, HYDROLASE, POLYMORPHISM, PROTEASE, SERINE PROTEASE
3s8v:A (PRO630) to (ALA666) CRYSTAL STRUCTURE OF LRP6-DKK1 COMPLEX | WNT, RECEPTOR, LRP5, LRP6, LDL RECEPTOR-LIKE PROTEIN, DICKKOPF (DKK), YWTD B-PROPELLER, SIGNALING PROTEIN
3s8v:A (LEU936) to (ALA969) CRYSTAL STRUCTURE OF LRP6-DKK1 COMPLEX | WNT, RECEPTOR, LRP5, LRP6, LDL RECEPTOR-LIKE PROTEIN, DICKKOPF (DKK), YWTD B-PROPELLER, SIGNALING PROTEIN
3s8z:A (LEU936) to (PRO974) CRYSTAL STRUCTURE OF LRP6-E3E4 | WNT, RECEPTOR, LRP5, LRP6, LDL RECEPTOR-LIKE PROTEIN, DICKKOPF (DKK), YWTD B-PROPELLER, SIGNALING PROTEIN
3f9f:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF THE F140A MUTANT OF SARS-CORONOVIRUS 3C-LIKE PROTEASE AT PH 6.0 | PROTEASE, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
3f9f:B (GLN110) to (TYR154) CRYSTAL STRUCTURE OF THE F140A MUTANT OF SARS-CORONOVIRUS 3C-LIKE PROTEASE AT PH 6.0 | PROTEASE, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
3f9g:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF THE F140A MUTANT OF SARS-CORONOVIRUS 3C-LIKE PROTEASE AT PH 6.5 | PROTEASE, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
3f9g:B (GLN110) to (TYR154) CRYSTAL STRUCTURE OF THE F140A MUTANT OF SARS-CORONOVIRUS 3C-LIKE PROTEASE AT PH 6.5 | PROTEASE, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
3fan:A (GLY89) to (THR124) CRYSTAL STRUCTURE OF CHYMOTRYPSIN-LIKE PROTEASE/PROTEINASE (3CLSP/NSP4) OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV) | CHYMOTRYPSIN-LIKE, N-TERMINAL BETA-BARRELS, C-TERMINAL ALPHA-BETA EXTRA DOMAIN, CANONICAL CATALYTIC TRIAD, HYDROLASE
3fao:A (VAL13) to (VAL51) CRYSTAL STRUCTURE OF S118A MUTANT 3CLSP OF PRRSV | CHYMOTRYPSIN-LIKE, N-TERMINAL BETA-BARRELS, C-TERMINAL ALPHA-BETA EXTRA DOMAIN, S118A MUTANT, HYDROLASE
3fao:A (GLY89) to (THR124) CRYSTAL STRUCTURE OF S118A MUTANT 3CLSP OF PRRSV | CHYMOTRYPSIN-LIKE, N-TERMINAL BETA-BARRELS, C-TERMINAL ALPHA-BETA EXTRA DOMAIN, S118A MUTANT, HYDROLASE
4hss:A (THR85) to (GLU143) STRUCTURE OF THE FULL-LENGTH MAJOR PILIN SPAD FROM CORYNEBACTERIUM DIPHTHERIAE | CNAA/CNAB FOLDED DOMAINS, MAJOR PILIN POLYMER, HOMOPOLYMER, ISOPEPTIDE BONDING BETWEEN LYS AND ASN SIDECHAINS, CELL ADHESION
2bx2:L (LYS43) to (ILE101) CATALYTIC DOMAIN OF E. COLI RNASE E | RNA-BINDING, RNA TURNOVER, RNA PROCESSING, HYDROLASE, ENDONUCLEASE, NUCLEASE
2bx3:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (P43212) | SARS, HYDROLASE, ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A- HELICES, VIRAL PROTEIN
2pjh:B (ARG144) to (ASP179) STRCTURAL MODEL OF THE P97 N DOMAIN- NPL4 UBD COMPLEX | P97, UFD1, NPL4, AAA, ATPASE, PROTEIN BINDING, TRANSPORT PROTEIN
4hyp:A (GLN132) to (PHE173) PYRROLOPYRIMIDINE INHIBITORS OF DNA GYRASE B AND TOPOISOMERASE IV, PART I: STRUCTURE GUIDED DISCOVERY AND OPTIMIZATION OF DUAL TARGETING AGENTS WITH POTENT, BROAD-SPECTRUM ENZYMATIC ACTIVITY. | GYRASE, GYRB, ATP-BINDING, NUCLEOTIDE-BINDING, TOPOISOMERASE, ATP- BINDING DOMAIN, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
4hyp:C (GLN132) to (LEU177) PYRROLOPYRIMIDINE INHIBITORS OF DNA GYRASE B AND TOPOISOMERASE IV, PART I: STRUCTURE GUIDED DISCOVERY AND OPTIMIZATION OF DUAL TARGETING AGENTS WITH POTENT, BROAD-SPECTRUM ENZYMATIC ACTIVITY. | GYRASE, GYRB, ATP-BINDING, NUCLEOTIDE-BINDING, TOPOISOMERASE, ATP- BINDING DOMAIN, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
4hyp:D (GLN132) to (PHE173) PYRROLOPYRIMIDINE INHIBITORS OF DNA GYRASE B AND TOPOISOMERASE IV, PART I: STRUCTURE GUIDED DISCOVERY AND OPTIMIZATION OF DUAL TARGETING AGENTS WITH POTENT, BROAD-SPECTRUM ENZYMATIC ACTIVITY. | GYRASE, GYRB, ATP-BINDING, NUCLEOTIDE-BINDING, TOPOISOMERASE, ATP- BINDING DOMAIN, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
4xeb:A (ASN202) to (THR237) THE STRUCTURE OF P. FUNICOLOSUM CEL7A | CELLULASE, PROCESSIVE, CBHI, CEL7, CELLOBIOSE, CELLOHEXAOSE, HYDROLASE
2pnh:B (GLY69) to (LEU99) ESCHERICHIA COLI PRIB E39A VARIANT | BETA BARREL, OB FOLD, DNA BINDING PROTEIN
3sgb:E (ASP29) to (ALA68) STRUCTURE OF THE COMPLEX OF STREPTOMYCES GRISEUS PROTEASE B AND THE THIRD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR AT 1.8 ANGSTROMS RESOLUTION | COMPLEX(SERINE PROTEINASE-INHIBITOR)
3sgq:E (ASP29) to (ALA68) GLN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7 | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1ca0:G (GLN30) to (GLY69) BOVINE CHYMOTRYPSIN COMPLEXED TO APPI | SERINE PROTEASE, INHIBITOR, PROTEASE-SUBSTRATE INTERACTIONS, COMPLEX (SERINE PROTEASE/INHIBITOR)
3fks:E (ASN35) to (GLY80) YEAST F1 ATPASE IN THE ABSENCE OF BOUND NUCLEOTIDES | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, ATP-BINDING, CF(1), HYDROGEN ION TRANSPORT, ION TRANSPORT, MEMBRANE, MITOCHONDRION, MITOCHONDRION INNER MEMBRANE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSPORT, HYDROLASE
3fks:F (ASN35) to (ASP78) YEAST F1 ATPASE IN THE ABSENCE OF BOUND NUCLEOTIDES | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, ATP-BINDING, CF(1), HYDROGEN ION TRANSPORT, ION TRANSPORT, MEMBRANE, MITOCHONDRION, MITOCHONDRION INNER MEMBRANE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSPORT, HYDROLASE
3fks:U (GLU53) to (ARG92) YEAST F1 ATPASE IN THE ABSENCE OF BOUND NUCLEOTIDES | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, ATP-BINDING, CF(1), HYDROGEN ION TRANSPORT, ION TRANSPORT, MEMBRANE, MITOCHONDRION, MITOCHONDRION INNER MEMBRANE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSPORT, HYDROLASE
3fks:V (ASN35) to (GLY80) YEAST F1 ATPASE IN THE ABSENCE OF BOUND NUCLEOTIDES | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, ATP-BINDING, CF(1), HYDROGEN ION TRANSPORT, ION TRANSPORT, MEMBRANE, MITOCHONDRION, MITOCHONDRION INNER MEMBRANE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSPORT, HYDROLASE
2c3s:A (GLN110) to (TYR154) STRUCTURE OF SARS COV MAIN PROTEINASE AT 1.9 A (PH6.5) | SARS COV, 3C-LIKE PROTEASE, MAIN PROTEASE, HYDROLASE
1chg:A (GLN30) to (GLY69) CHYMOTRYPSINOGEN,2.5 ANGSTROMS CRYSTAL STRUCTURE, COMPARISON WITH ALPHA-CHYMOTRYPSIN,AND IMPLICATIONS FOR ZYMOGEN ACTIVATION | HYDROLASE ZYMOGEN (SERINE PROTEINASE)
3sn8:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH CM- FF-H (SOAKING) | 3C-LIKE PROTEINASE, PROTEASE, CM-FF-H, ACTIVE SITE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3snb:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AC- DSFDQ-H (SOAKING) | 3C-LIKE PROTEINASE, PROTEASE, AC-DSFDQ-H, COVALENT BOUND, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3sne:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AC- ESTLQ-H (SOAKING) | SARS CORONAVIRUS MAIN PROTEASE, 3C-LIKE PROTEINASE, PROTEASE, INHIBITOR AC-ESTLQ-H, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3sos:A (GLN402) to (GLY447) BENZOTHIAZINONE INHIBITOR IN COMPLEX WITH FXIA | HYDROLASE, SERINE PROTEASE, COAGULATION FACTOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1cr5:B (GLN150) to (ILE197) N-TERMINAL DOMAIN OF SEC18P | DOUBLE-PSI BETA BARREL, VESICLE FUSION, ENDOCYTOSIS/EXOCYTOSIS COMPLEX
4ic5:B (VAL103) to (ALA169) CRYSTAL STRUCTURE OF DEG5 | BETS-BARREL, ENDOPEPTIDASE, CALCIUM BINDING, CHLOROPLAST, HYDROLASE
1oxg:A (GLN30) to (GLY69) CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN ORGANIC SOLVENT TREATED BOVINE ALPHA-CHYMOTRYPSIN AND ITS AUTOCATALYTICALLY PRODUCED HIGHLY POTENT 14-RESIDUE PEPTIDE AT 2.2 RESOLUTION | AUTOCATALYSIS, ORGANIC SOLVENT TREATMENT, INHIBITION, HYDROLASE
1ct0:E (ASP29) to (ALA68) CRYSTAL STRUCTURE OF THE OMTKY3 P1 VARIANT OMTKY3-SER18I IN COMPLEX WITH SGPB | ENZYME-INHIBITOR COMPLEX, BETA-BRANCHED P1 RESIDUE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1ct2:E (ASP29) to (ALA68) CRYSTAL STRUCTURE OF THE OMTKY3 P1 VARIANT OMTKY3-THR18I IN COMPLEX WITH SGPB | ENZYME-INHIBITOR COMPLEX, BETA-BRANCHED P1 RESIDUE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1ct4:E (ASP29) to (ALA68) CRYSTAL STRUCTURE OF THE OMTKY3 P1 VARIANT OMTKY3-VAL18I IN COMPLEX WITH SGPB | ENZYME-INHIBITOR COMPLEX, BETA-BRANCHED P1 RESIDUE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3fve:A (GLY143) to (ASP190) CRYSTAL STRUCTURE OF DIAMINOPIMELATE EPIMERASE MYCOBACTERIUM TUBERCULOSIS DAPF | ALPHA/BETA, AMINO-ACID BIOSYNTHESIS, ISOMERASE, LYSINE BIOSYNTHESIS
4ifd:H (VAL113) to (ASN170) CRYSTAL STRUCTURE OF AN 11-SUBUNIT EUKARYOTIC EXOSOME COMPLEX BOUND TO RNA | EXOSOME, RNA, RRP44, DIS3, PIN, RRP6, EXONUCLEASE, ENDONUCLEASE, HYDROLASE, NUCLEASE, RIBONUCLEASE, RNA PROCESSING, HYDROLASE-RNA COMPLEX
2q6g:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE H41A MUTANT IN COMPLEX WITH AN N-TERMINAL SUBSTRATE | CORONAVIRUS; SARS-COV; MAIN PROTEASE; 3C-LIKE PROTEINASE;SUBSTRATE, HYDROLASE
1p03:A (ILE29) to (ILE80) STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1p04:A (ILE29) to (ILE80) STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1p05:A (ILE29) to (ILE80) STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2q7n:A (ILE36) to (GLU64) CRYSTAL STRUCTURE OF LEUKEMIA INHIBITORY FACTOR IN COMPLEX WITH LIF RECEPTOR (DOMAINS 1-5) | CYTOKINE CELL SURFACE RECEPTOR COMPLEX LIFR LIF, CYTOKINE RECEPTOR- CYTOKINE COMPLEX
1p10:A (ILE29) to (ILE80) STRUCTURAL PLASTICITY AS A DETERMINANT OF ENZYME SPECIFICITY. CREATING BROADLY SPECIFIC PROTEASES | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1p11:E (ILE29) to (ILE80) CRYSTAL STRUCTURES OF ALPHA-LYTIC PROTEASE COMPLEXES WITH IRREVERSIBLY BOUND PHOSPHONATE ESTERS | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1p12:E (ILE29) to (ILE80) CRYSTAL STRUCTURES OF ALPHA-LYTIC PROTEASE COMPLEXES WITH IRREVERSIBLY BOUND PHOSPHONATE ESTERS | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ii3:C (GLY207) to (ASN251) CRYSTAL STRUCTURE OF S. POMBE UBIQUITIN ACTIVATING ENZYME 1 (UBA1) IN COMPLEX WITH UBIQUITIN AND ATP/MG | ROSSMANN-LIKE FOLD, UBIQUITIN-LIKE FOLD, UBIQUITIN ACTIVATING ENZYME ACTIVITY, ATP BINDING, LIGASE ACTIVITY, ATP/MG BINDING, UBIQUITIN E2 BINDING, LIGASE
2qe7:A (GLU51) to (ARG90) CRYSTAL STRUCTURE OF THE F1-ATPASE FROM THE THERMOALKALIPHILIC BACTERIUM BACILLUS SP. TA2.A1 | BLOCKAGE OF ATP HYDROLYSIS, F1-ATPASE, ATP SYNTHASE, SINGLE PARTICLE ANALYSIS, THERMOALKALIPHILIC, HYDROLASE
2qe7:B (GLU51) to (ARG90) CRYSTAL STRUCTURE OF THE F1-ATPASE FROM THE THERMOALKALIPHILIC BACTERIUM BACILLUS SP. TA2.A1 | BLOCKAGE OF ATP HYDROLYSIS, F1-ATPASE, ATP SYNTHASE, SINGLE PARTICLE ANALYSIS, THERMOALKALIPHILIC, HYDROLASE
2qe7:C (GLU51) to (ARG90) CRYSTAL STRUCTURE OF THE F1-ATPASE FROM THE THERMOALKALIPHILIC BACTERIUM BACILLUS SP. TA2.A1 | BLOCKAGE OF ATP HYDROLYSIS, F1-ATPASE, ATP SYNTHASE, SINGLE PARTICLE ANALYSIS, THERMOALKALIPHILIC, HYDROLASE
3szn:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AN ALPHA, BETA-UNSATURATED ETHYL ESTER SG75 | SARS CORONAVIRUS MAIN PROTEASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ils:C (HIS253) to (PRO281) CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR117 | STRUCTURAL GENOMICS, PSI-BIOLOGY, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, MBH ENZYME DESIGN, UNKNOWN FUNCTION
4xsx:A (ASP96) to (ARG148) CRYSTAL STRUCTURE OF CBR 703 BOUND TO ESCHERICHIA COLI RNA POLYMERASE HOLOENZYME | BACTERIAL RNA POLYMERASE ANTIBIOTIC COMPLEX, TRANSCRIPTION-ANTIBIOTIC COMPLEX
4xsx:G (ASP96) to (ARG148) CRYSTAL STRUCTURE OF CBR 703 BOUND TO ESCHERICHIA COLI RNA POLYMERASE HOLOENZYME | BACTERIAL RNA POLYMERASE ANTIBIOTIC COMPLEX, TRANSCRIPTION-ANTIBIOTIC COMPLEX
3t2n:A (GLN177) to (GLY220) HUMAN HEPSIN PROTEASE IN COMPLEX WITH THE FAB FRAGMENT OF AN INHIBITORY ANTIBODY | TYPE II TRANSMEMBRANE SERINE PROTEASE, SRCR DOMAIN, SUBSTRATES INCLUDE PRO-HEPSIN, PRO-HGF, LAMININ-332, TRANSMEMBRANE, HYDROLASE
3t2n:B (GLN177) to (GLY220) HUMAN HEPSIN PROTEASE IN COMPLEX WITH THE FAB FRAGMENT OF AN INHIBITORY ANTIBODY | TYPE II TRANSMEMBRANE SERINE PROTEASE, SRCR DOMAIN, SUBSTRATES INCLUDE PRO-HEPSIN, PRO-HGF, LAMININ-332, TRANSMEMBRANE, HYDROLASE
3gcd:D (VAL168) to (TRP205) STRUCTURE OF THE V. CHOLERAE RTX CYSTEINE PROTEASE DOMAIN IN COMPLEX WITH AN AZA-LEUCINE PEPTIDE INHIBITOR | V. CHOLERAE, REPEATS-IN-TOXIN, MARTX, CYSTEINE PROTEASE, INOSITOL HEXAKISPHOSPHATE, AZA-PEPTIDE, AZA-LEU, TOXIN-INHIBITOR COMPLEX
3giq:B (ASP427) to (ASN458) CRYSTAL STRUCTURE OF N-ACYL-D-GLUTAMATE DEACYLASE FROM BORDETELLA BRONCHISEPTICA COMPLEXED WITH ZINC AND PHOSPHONATE INHIBITOR, A MIMIC OF THE REACTION TETRAHEDRAL INTERMEDIATE. | N-ACYL-D-GLUTAMATE DEACYLASE, AMIDOHYDROLASE, REACTION INTERMEDIATE, HYDROLASE
3gip:A (ASP427) to (ASN458) CRYSTAL STRUCTURE OF N-ACYL-D-GLUTAMATE DEACYLASE FROM BORDETELLA BRONCHISEPTICA COMPLEXED WITH ZINC, ACETATE AND FORMATE IONS. | N-ACYL-D-GLUTAMATE DEACYLASE, AMIDOHYDROLASE FAMILY, CRYSTAL STRUCTURE, HYDROLASE
2qv1:A (GLU58) to (SER92) CRYSTAL STRUCTURE OF HCV NS3-4A V36M MUTANT | HCV, PROTEASE, NS3-4A, V36M MUTNAT, CRYSTAL STRUCTURE, HYDROLASE
2d2i:P (ILE174) to (GLN250) CRYSTAL STRUCTURE OF NADP-DEPENDENT GLYCERALDEHYDE-3- PHOSPHATE DEHYDROGENASE FROM SYNECHOCOCCUS SP. COMPLEXED WITH NADP+ | GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE, ROSSMANN FOLD, PROTEIN-NADP+ COMPLEX, OXIDOREDUCTASE
1pto:D (ARG79) to (GLU102) THE STRUCTURE OF A PERTUSSIS TOXIN-SUGAR COMPLEX AS A MODEL FOR RECEPTOR BINDING | TOXIN
1e1q:D (ALA35) to (ASP77) BOVINE MITOCHONDRIAL F1-ATPASE AT 100K | ATP PHOSPHORYLASE, ATP PHOSPHORYLASE (H+ TRANSPORTING), ATP SYNTHASE, F1FO ATP SYNTHASE, F1-ATPASE
4j0w:A (VAL391) to (PHE429) STRUCTURE OF U3-55K | BETA-PROPELLER, WD DOMAIN, RNA BINDING PROTEIN, PRERIBOSOME
3gnq:C (GLU173) to (ARG252) CRYSTAL STRUCTURE OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, TYPE I FROM BURKHOLDERIA PSEUDOMALLEI | DECODE BIOSTRUCTURES, SSGCID, UWPPG, SBRI, NIAID, OXIDOREDUCTASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
4j2k:B (SER118) to (HIS173) CRYSTAL STRUCTURE OF A PLANT TRYPSIN INHIBITOR ECTI | TREFOIL, SERINE PROTEASE INHIBITOR, HYDROLASE INHIBITOR
4j3x:A (CYS30) to (SER61) CRYSTAL STRUCTURE OF BARLEY LIMIT DEXTRINASE (E510A MUTANT) IN COMPLEX WITH A BRANCHED MALTOHEPTASACCHARIDE | GH13 HYDROLASE, HYDROLASE
3grw:H (VAL89) to (SER112) FGFR3 IN COMPLEX WITH A FAB | FGFR3, FAB, PROTEIN-PROTEIN COMPLEX, RECEPTOR TYROSINE KINASE, ATP- BINDING, IMMUNOGLOBULIN DOMAIN, KINASE, MEMBRANE, NUCLEOTIDE- BINDING, RECEPTOR, TRANSFERASE, TRANSMEMBRANE, TYROSINE-PROTEIN KINASE, TRANSFERASE-IMMUNE SYSTEM COMPLEX
1e79:E (ALA35) to (ASP77) BOVINE F1-ATPASE INHIBITED BY DCCD (DICYCLOHEXYLCARBODIIMIDE) | ATP PHOSPHORYLASE, ATP PHOSPHORYLASE (H+ TRANSPORTING), F1FO ATP SYNTHASE, CENTRAL STALK, HYDROLASE
3tew:A (ASN268) to (ASN368) CRYSTAL STRUCTURE OF ANTHRAX PROTECTIVE ANTIGEN (MEMBRANE INSERTION LOOP DELETED) TO 1.45-A RESOLUTION | PROTEIN TRANSPORT, TOXIN
1e7v:A (PHE473) to (ALA528) STRUCTURE DETERMINANTS OF PHOSPHOINOSITIDE 3-KINASE INHIBITION BY WORTMANNIN, LY294002, QUERCETIN, MYRICETIN AND STAUROSPORINE | TRANSFERASE, SECONDARY MESSENGER GENERATION PI3K, PI 3K, LY294002
1q2w:A (GLY109) to (TYR154) X-RAY CRYSTAL STRUCTURE OF THE SARS CORONAVIRUS MAIN PROTEASE | SARS-COV MAIN PROTEASE, THREE DOMAIN PROTEIN (TWO ANTIPARALLEL BETA BARRELS, ONE ALPHA HELICAL), HYDROLASE
1q2w:B (GLN110) to (TYR154) X-RAY CRYSTAL STRUCTURE OF THE SARS CORONAVIRUS MAIN PROTEASE | SARS-COV MAIN PROTEASE, THREE DOMAIN PROTEIN (TWO ANTIPARALLEL BETA BARRELS, ONE ALPHA HELICAL), HYDROLASE
3gto:H (ILE9) to (ALA60) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 15MER RNA | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, ZINC- FINGER, DNA DAMAGE, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
3gtp:H (LEU5) to (ALA60) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 24MER RNA | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA- DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, TRANSFERASE/DNA-RNA HYBRID COMPLEX
3tiu:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AN ALPHA,BETA-UNSATURATED ETHYL ESTER INHIBITOR SG82 | CORONAVIRUS MAIN PROTEASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3tj9:A (SER19) to (GLU67) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI UREE BOUND TO ZN2+ | METAL BINDING PROTEIN, UREASE ACCESSORY PROTEIN
3gtq:H (ILE9) to (ALA60) BACKTRACKED RNA POLYMERASE II COMPLEX INDUCED BY DAMAGE | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, ZINC- FINGER, DNA DAMAGE, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
3tjn:D (PHE278) to (LEU335) HTRA1 CATALYTIC DOMAIN, APO FORM | PROTEASE, HYDROLASE
3tns:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AN ALPHA, BETA-UNSATURATED ETHYL ESTER INHIBITOR SG83 | 3C-LIKE PROTEASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3tnt:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AN ALPHA, BETA-UNSATURATED ETHYL ESTER INHIBITOR SG85 | 3C-LIKE PROTEASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ei1:A (GLN128) to (PHE169) DIMERIZATION OF E. COLI DNA GYRASE B PROVIDES A STRUCTURAL MECHANISM FOR ACTIVATING THE ATPASE CATALYTIC CENTER | ATPASE DOMAIN, DIMER, ISOMERASE
1qdn:A (GLN128) to (VAL178) AMINO TERMINAL DOMAIN OF THE N-ETHYLMALEIMIDE SENSITIVE FUSION PROTEIN (NSF) | DOUBLE-PSI BETA BARREL ALPHA/BETA BARREL, VESICULAR-FUSION PROTEIN
3h09:A (LYS443) to (GLY470) THE STRUCTURE OF HAEMOPHILUS INFLUENZAE IGA1 PROTEASE | SERINE PROTEASE, IMMUNOGLOBULIN A1, BETA HELIX, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, TRANSMEMBRANE, VIRULENCE, ZYMOGEN
3h09:B (LYS443) to (GLY470) THE STRUCTURE OF HAEMOPHILUS INFLUENZAE IGA1 PROTEASE | SERINE PROTEASE, IMMUNOGLOBULIN A1, BETA HELIX, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, TRANSMEMBRANE, VIRULENCE, ZYMOGEN
2rf8:B (ILE30) to (GLY56) CRYSTAL STRUCTURE OF THE MUTANT C2A CONJUGATED BILE ACID HYDROLASE FROM CLOSTRIDIUM PERFRINGENS | CHOLOYLGLYCINE HYDROLASE, BILE SALT HYDROLASE, CBAH, BSH, NTN- HYDROLASE, HYDROLASE
2rfz:B (TYR206) to (THR240) CRYSTAL STRUCTURE OF CELLOBIOHYDROLASE FROM MELANOCARPUS ALBOMYCES COMPLEXED WITH CELLOTRIOSE | HYDROLASE, GLYCOSIDASE
2rfz:D (TYR206) to (THR240) CRYSTAL STRUCTURE OF CELLOBIOHYDROLASE FROM MELANOCARPUS ALBOMYCES COMPLEXED WITH CELLOTRIOSE | HYDROLASE, GLYCOSIDASE
1qh6:A (GLY113) to (SER160) CATALYSIS AND SPECIFICITY IN ENZYMATIC GLYCOSIDE HYDROLASES: A 2,5B CONFORMATION FOR THE GLYCOSYL-ENZYME INTERMIDIATE REVEALED BY THE STRUCTURE OF THE BACILLUS AGARADHAERENS FAMILY 11 XYLANASE | GLYCOSYL HYDROLASE
1ep5:A (GLY198) to (ASP232) CRYSTAL STRUCTURE OF THE CONSERVED CORE DOMAIN OF VENEZUALAN EQUINE ENCEPHALITIS CAPSID PROTEIN | BETA BARREL, HYDROLASE
1ep6:B (GLY198) to (ASP232) CRYSTAL STRUCTURE OF THE CONSERVED CORE DOMAIN OF VENEZUALAN EQUINE ENCEPHALITIS CAPSID PROTEIN | BETA BARREL, HYDROLASE
1etz:H (THR94) to (SER125) THE THREE-DIMENSIONAL STRUCTURE OF AN ANTI-SWEETENER FAB, NC10.14, SHOWS THE EXTENT OF STRUCTURAL DIVERSITY IN ANTIGEN RECOGNITION BY IMMUNOGLOBULINS | ANTI-SWEETENER FAB, ANTIGEN-ANTIBODY, COMPLEX, CRYSTAL STRUCTURE, RECEPTOR MIMICRY, ANTIGEN RECOGNITION, IMMUNE SYSTEM
4jkr:A (ASP96) to (ARG148) CRYSTAL STRUCTURE OF E. COLI RNA POLYMERASE IN COMPLEX WITH PPGPP | RNA POLYMERASE, TRANSCRIPTION REGULATION, TRANSCRIPTION, TRANSFERASE
1ev7:A (ALA104) to (LEU151) CRYSTAL STRUCTURE OF DNA RESTRICTION ENDONUCLEASE NAEI | APO-NAEI, RESTRICTION ENDONUCLEASE, TOPOISOMERASE, HELIX- TURN-HELIX, CAP, HYDROLASE
2sfa:A (GLU5) to (THR45) SERINE PROTEINASE FROM STREPTOMYCES FRADIAE ATCC 14544 | HYDROLASE, SERINE PROTEASE
2sgd:E (ASP29) to (ALA68) ASP 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7 | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
2sgf:E (ASP29) to (ALA68) PHE 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
2sge:E (ASP29) to (ALA68) GLU 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7 | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
2sgq:E (ASP29) to (ALA68) GLN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5 | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
4jps:A (ASP434) to (PHE486) CO-CRYSTAL STRUCTURES OF THE LIPID KINASE PI3K ALPHA WITH PAN AND ISOFORM SELECTIVE INHIBITORS | CLASS I PHOSPHATIDYLINOSITOL 3-KINASES, P85 ALPHA, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
1qq4:A (ILE7) to (GLY47) CRYSTAL STRUCTURE OF AN ALPHA-LYTIC PROTEASE MUTANT WITH ACCELERATED FOLDING KINETICS, R102H/G134S | DOUBLE BETA BARREL, BACTERIAL SERINE PROTEASE, HYDROLASE
1qrw:A (ILE7) to (GLY47) CRYSTAL STRUCTURE OF AN ALPHA-LYTIC PROTEASE MUTANT WITH ACCELERATED FOLDING KINETICS, R102H/G134S, PH 8 | PROTEIN FOLDING, FOLDING KINETICS, PRO REGION, HYDROLASE
1qrx:A (ILE7) to (GLY47) CRYSTAL STRUCTURE OF WILD-TYPE ALPHA-LYTIC PROTEASE AT 1.6 A, PH 5.14 | PROTEIN FOLDING, PRO REGION, HYDROLASE
4ykn:A (ASP1434) to (PHE1486) PI3K ALPHA LIPID KINASE WITH ACTIVE SITE INHIBITOR | "LIPID KINASE", INHIBITOR, COMPLEX, PI3K, PI3K ALPHA, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2ea3:A (ASN7) to (ASN42) CRYSTAL STRUCTURE OF CELLULOMONAS BOGORIENSIS CHYMOTRYPSIN | CELLOULOMONAS, CHYMOTRYPSIN, PROTEASE, HYDROLASE
4jxb:A (ASP121) to (LEU167) RIPD (RV1566C) FROM MYCOBACTERIUM TUBERCULOSIS: A NON-CATALYTIC NLPC/P60 DOMAIN PROTEIN, ADAPTATION TO PEPTIDOGLYCAN-BINDING FUNCTION | CELL WALL, ENVELOPE BIOGENESIS, NLPC/P60, CELL INVASION
4k1e:A (GLN30) to (GLY69) ATOMIC RESOLUTION CRYSTAL STRUCTURES OF KALLIKREIN-RELATED PEPTIDASE 4 COMPLEXED WITH A MODIFIED SFTI INHIBITOR FCQR | PROTEIN-PEPTIDE COMPLEX, BOWMAN-BIRK INHIBITOR, PROTEASE, PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4k4k:A (ASP57) to (TYR111) CRYSTAL STRUCTURE OF A PUTATIVE CELL ADHESION PROTEIN (BACUNI_00621) FROM BACTEROIDES UNIFORMIS ATCC 8492 AT 1.67 A RESOLUTION | FIMBRILLIN-LIKE PROTEIN, PF13149 FAMILY, DUF3988, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, CELL ADHESION
4k4k:B (GLY56) to (TYR111) CRYSTAL STRUCTURE OF A PUTATIVE CELL ADHESION PROTEIN (BACUNI_00621) FROM BACTEROIDES UNIFORMIS ATCC 8492 AT 1.67 A RESOLUTION | FIMBRILLIN-LIKE PROTEIN, PF13149 FAMILY, DUF3988, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, CELL ADHESION
2v5p:A (PRO1894) to (CYS1957) COMPLEX STRUCTURE OF HUMAN IGF2R DOMAINS 11-13 BOUND TO IGF-II | RECEPTOR/GLYCOPROTEIN, CATION INDEPENDENT MANNOSE 6-PHOSPHATE, MEMBRANE, RECEPTOR, LYSOSOME, TRANSPORT, BETA BARREL, PHOSPHORYLATION, FIBRONECTIN TYPE II, INSULIN-LIKE GROWTH FACTOR, RECEPTOR/GLYCOPROTEIN COMPLEX, POLYMORPHISM, GLYCOPROTEIN, TRANSMEMBRANE
2v6n:A (GLY109) to (TYR154) CRYSTAL STRUCTURES OF THE SARS-CORONAVIRUS MAIN PROTEINASE INACTIVATED BY BENZOTRIAZOLE COMPOUNDS | THIOL PROTEASE, RNA REPLICATION, MAIN PROTEINASE, RIBOSOMAL FRAMESHIFT, SARS, PROTEASE, HYDROLASE, POLYPROTEIN, VIRAL PROTEIN
1red:A (GLY106) to (ALA153) ENDO-1,4-BETA-XYLANASE II COMPLEX WITH 4,5-EPOXYPENTYL-BETA- D-XYLOSIDE | XYLANASE, XYLAN DEGRADATION, HYDROLASE
4k74:A (LEU33) to (PRO71) THE UMUC SUBUNIT OF THE E. COLI DNA POLYMERASE V SHOWS A UNIQUE INTERACTION WITH THE BETA-CLAMP PROCESSIVITY FACTOR. | DNA REPLICATION CLAMP PROCESSIVITY FACTOR, DNA REPLICATION/REPAIR, DNA BINDING PROTEIN-TRANSFERASE COMPLEX
4k8y:A (GLN30) to (GLY69) ATOMIC RESOLUTION CRYSTAL STRUCTURES OF KALLIKREIN-RELATED PEPTIDASE 4 COMPLEXED WITH SUNFLOWER TRYPSIN INHIBITOR (SFTI-1) | BOWMAN-BIRK INHIBITOR, PROTEASE, PROTEASE INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
1rjp:A (ASP428) to (ASN459) CRYSTAL STRUCTURE OF D-AMINOACYLASE IN COMPLEX WITH 100MM CUCL2 | TIM BARREL, BETA BARREL, INSERTION, HYDROLASE
4yw7:H (ALA64) to (TYR98) STRUCTURAL INSIGHT INTO DIVALENT GALACTOSIDE BINDING TO PSEUDOMONAS AERUGINOSA LECTIN LECA | GALACTOSIDES, LECTINS, SUGAR BINDING PROTEIN
1rk6:A (ASP428) to (ASN459) THE ENZYME IN COMPLEX WITH 50MM CDCL2 | TIM BARREL, BETA BARREL, INSERTION, HYDROLASE
1rl2:A (PRO74) to (GLY118) RIBOSOMAL PROTEIN L2 RNA-BINDING DOMAIN FROM BACILLUS STEAROTHERMOPHILUS | RIBOSOMAL PROTEIN, RNA-BINDING DOMAIN, PEPTIDYLTRANSFEREASE CENTER, X-RAY DIFFRACTION
2f4l:A (LEU168) to (LYS202) CRYSTAL STRUCTURE OF A PUTATIVE ACETAMIDASE (TM0119) FROM THERMOTOGA MARITIMA MSB8 AT 2.50 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, HYDROLASE
2f4l:C (LEU168) to (LYS202) CRYSTAL STRUCTURE OF A PUTATIVE ACETAMIDASE (TM0119) FROM THERMOTOGA MARITIMA MSB8 AT 2.50 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, HYDROLASE
2f4l:D (LEU168) to (LYS202) CRYSTAL STRUCTURE OF A PUTATIVE ACETAMIDASE (TM0119) FROM THERMOTOGA MARITIMA MSB8 AT 2.50 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, HYDROLASE
1fx0:A (GLU52) to (ALA91) CRYSTAL STRUCTURE OF THE CHLOROPLAST F1-ATPASE FROM SPINACH | LATENT ATPASE, THERMAL STABILITY, POTENTIAL TENTOXIN BINDING SITE, HYDROLASE
4yy8:B (SER681) to (ILE726) CRYSTAL STRUCTURE ANALYSIS OF KELCH PROTEIN FROM PLASMODIUM FALCIPARUM | STRUCTURAL GENOMICS CONSORTIUM, SGC, PUTATIVE KELCH PROTEIN, K13, UNKNOWN FUNCTION
2f83:A (GLN384) to (SER428) CRYSTAL STRUCTURE AT 2.9 ANGSTROMS RESOLUTION OF HUMAN PLASMA COAGULATION FACTOR XI ZYMOGEN | PROTEASE, APPLE DOMAIN, HYDROLASE
1rrk:A (TRP470) to (GLY517) CRYSTAL STRUCTURE ANALYSIS OF THE BB SEGMENT OF FACTOR B | FACTOR B, BB, HYDROLASE
1rs0:A (TRP470) to (GLY517) CRYSTAL STRUCTURE ANALYSIS OF THE BB SEGMENT OF FACTOR B COMPLEXED WITH DI-ISOPROPYL-PHOSPHATE (DIP) | FACTOR B, BB, FACTOR BB-DIP COMPLEX, HYDROLASE
2f9n:A (GLN30) to (LEU68) CRYSTAL STRUCTURE OF THE RECOMBINANT HUMAN ALPHA I TRYPTASE MUTANT K192Q/D216G IN COMPLEX WITH LEUPEPTIN | SERINE PROTEINASE, LEUPEPTIN, TRYPSIN-LIKE, DIFUCOSYLATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2f9n:C (GLN30) to (LEU68) CRYSTAL STRUCTURE OF THE RECOMBINANT HUMAN ALPHA I TRYPTASE MUTANT K192Q/D216G IN COMPLEX WITH LEUPEPTIN | SERINE PROTEINASE, LEUPEPTIN, TRYPSIN-LIKE, DIFUCOSYLATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2f9o:D (GLN30) to (LEU68) CRYSTAL STRUCTURE OF THE RECOMBINANT HUMAN ALPHA I TRYPTASE MUTANT D216G | SERINE PROTEINASE, TRYPSIN-LIKE, DIFUCOSYLATION, HYDROLASE
4kel:A (GLN30) to (GLY69) ATOMIC RESOLUTION CRYSTAL STRUCTURE OF KALLIKREIN-RELATED PEPTIDASE 4 COMPLEXED WITH A MODIFIED SFTI INHIBITOR FCQR(N) | BOWMAN-BIRK INHIBITOR, PROTEASE, PROTEASE INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
1rtk:A (TRP470) to (GLY517) CRYSTAL STRUCTURE ANALYSIS OF THE BB SEGMENT OF FACTOR B COMPLEXED WITH 4-GUANIDINOBENZOIC ACID | FACTOR B, BB, FACTOR BB-INHIBITOR COMPLEX, HORMONE/GROWTH FACTOR COMPLEX
1rtl:B (GLU32) to (SER66) CRYSTAL STRUCTURE OF HCV NS3 PROTEASE DOMAIN: NS4A PEPTIDE COMPLEX WITH COVALENTLY BOUND PYRROLIDINE-5,5-TRANSLACTAM INHIBITOR | VIRAL PROTEIN, SERINE PROTEASE, NONSTRUCTURAL PROTEIN, COFACTOR PEPTIDE, HELICASE, INHIBITOR, TRANSLACTAM, VIRAL PROTEIN COMPLEX
2fda:A (GLN30) to (SER69) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN COAGULATION FACTOR XIA IN COMPLEX WITH ALPHA-KETOTHIAZOLE ARGININE DERIVED LIGAND | FXIA, INHIBITOR, HYDROLASE
1rve:B (GLU101) to (ILE192) THE CRYSTAL STRUCTURE OF ECORV ENDONUCLEASE AND OF ITS COMPLEXES WITH COGNATE AND NON-COGNATE DNA FRAGMENTS | ENDONUCLEASE
2vgd:A (GLY110) to (GLY157) CRYSTAL STRUCTURE OF ENVIRONMENTAL ISOLATED GH11 IN COMPLEX WITH XYLOBIOSE AND FERULOYL-ARABINO-XYLOTRIOSE | GLYCOSIDE HYDROLASE, XYLANASE, BETA JELLY ROLL, HYDROLASE
3ure:A (ILE31) to (ILE66) REPACK MUTANT (T181I, W199L, Q210I) OF ALPHA-LYTIC PROTEASE | SERINE PROTEASE, HYDROLASE
3ure:B (ILE31) to (GLY67) REPACK MUTANT (T181I, W199L, Q210I) OF ALPHA-LYTIC PROTEASE | SERINE PROTEASE, HYDROLASE
2vid:A (GLY17) to (HIS53) SERINE PROTEASE SPLB FROM STAPHYLOCOCCUS AUREUS AT 1.8A RESOLUTION | PROTEASE, SERINE PROTEASE, STAPHYLOCOCCUS AUREUS, HYDROLASE
1gae:O (ILE168) to (LYS248) COMPARISON OF THE STRUCTURES OF WILD TYPE AND A N313T MUTANT OF ESCHERICHIA COLI GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASES: IMPLICATION FOR NAD BINDING AND COOPERATIVITY | OXIDOREDUCTASE (ALDEHYDE(D)-NAD+(A))
1gbe:A (ILE31) to (ILE66) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU | ACTIVE-SITE MUTATION, HYDROLASE (SERINE PROTEINASE)
1gbh:A (ILE31) to (ILE66) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gbi:A (ILE31) to (ILE66) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gbl:A (ILE31) to (ILE66) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2fnq:A (ALA374) to (GLN429) INSIGHTS FROM THE X-RAY CRYSTAL STRUCTURE OF CORAL 8R- LIPOXYGENASE: CALCIUM ACTIVATION VIA A C2-LIKE DOMAIN AND A STRUCTURAL BASIS OF PRODUCT CHIRALITY | BETA-BARREL, EICOSANOID, FATTY ACID, C2-LIKE DOMAIN, OXIDOREDUCTASE
2fnq:B (ALA374) to (GLN429) INSIGHTS FROM THE X-RAY CRYSTAL STRUCTURE OF CORAL 8R- LIPOXYGENASE: CALCIUM ACTIVATION VIA A C2-LIKE DOMAIN AND A STRUCTURAL BASIS OF PRODUCT CHIRALITY | BETA-BARREL, EICOSANOID, FATTY ACID, C2-LIKE DOMAIN, OXIDOREDUCTASE
2fs8:A (GLN30) to (LEU68) HUMAN BETA-TRYPTASE II WITH INHIBITOR CRA-29382 | SERINE PROTEASE, PROTEINASE, 29382, HYDROLASE
2fs9:D (GLN30) to (LEU68) HUMAN BETA TRYPTASE II WITH INHIBITOR CRA-28427 | SERINE PROTEASE, SERINE PROTEINASE, 28427, HYDROLASE
1gh7:A (VAL33) to (ASP92) CRYSTAL STRUCTURE OF THE COMPLETE EXTRACELLULAR DOMAIN OF THE BETA- COMMON RECEPTOR OF IL-3, IL-5, AND GM-CSF | DIMER OF INTERLOCKING CHAINS OF FIBRONECTIN-III DOMAINS FOUR FIBRONECTIN-III DOMAINS PER CHAIN, CYTOKINE RECEPTOR
1gh7:B (VAL33) to (ASP92) CRYSTAL STRUCTURE OF THE COMPLETE EXTRACELLULAR DOMAIN OF THE BETA- COMMON RECEPTOR OF IL-3, IL-5, AND GM-CSF | DIMER OF INTERLOCKING CHAINS OF FIBRONECTIN-III DOMAINS FOUR FIBRONECTIN-III DOMAINS PER CHAIN, CYTOKINE RECEPTOR
3v3m:A (GLN110) to (TYR154) SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS (SARS-COV) 3CL PROTEASE IN COMPLEX WITH N-[(1R)-2-(TERT-BUTYLAMINO)-2-OXO-1-(PYRIDIN-3-YL) ETHYL]-N-(4-TERT-BUTYLPHENYL)FURAN-2-CARBOXAMIDE INHIBITOR. | CHYMOTRYPSIN LIKE FOLD, VIRAL POLYPEPTIDE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2fww:D (GLN30) to (LEU68) HUMAN BETA-TRYPTASE II COMPLEXED WITH 4-PIPERIDINEBUTYRATE TO MAKE ACYLENZYME | SERINE PROTEASE, PROTEINASE, 29382, HYDROLASE
3v64:C (GLU439) to (ILE471) CRYSTAL STRUCTURE OF AGRIN AND LRP4 | BETA PROPELLER, LAMININ-G, SIGNALING, PROTEIN BINDING
1sgd:E (ASP29) to (ALA68) ASP 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5 | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1sge:E (ASP29) to (ALA68) GLU 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5 | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1sgn:E (ASP29) to (ALA68) ASN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1sgr:E (ASP29) to (ALA68) LEU 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B | SERINE PROTEINASE, PROTEIN INHIBITOR, COMPLEX (SERINE PROTEASE/INHIBITOR) COMPLEX
1sgp:E (ASP29) to (ALA68) ALA 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B | SERINE PROTEINASE, PROTEIN INHIBITOR, COMPLEX (SERINE PROTEASE/INHIBITOR) COMPLEX
1sgq:E (ASP29) to (ALA68) GLY 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B | SERINE PROTEINASE, PROTEIN INHIBITOR, COMPLEX (SERINE PROTEASE/INHIBITOR) COMPLEX
1sgy:E (ASP29) to (ALA68) TYR 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5 | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
2vpj:A (ARG521) to (GLU567) CRYSTAL STRUCTURE OF THE KELCH DOMAIN OF HUMAN KLHL12 | ADAPTOR PROTEIN, WNT SIGNALING PATHWAY, PROTEIN-BINDING, UBIQUITIN DEGRADATION, UBL CONJUGATION PATHWAY, CUL3, KELCH REPEAT, PHOSPHOPROTEIN, WNT SIGNALLING
2g2n:C (THR23) to (VAL65) CRYSTAL STRUCTURE OF E.COLI TRANSTHYRETIN-RELATED PROTEIN WITH BOUND ZN | TRANSTHYRETIN, TRANSTHYRETIN-RELATED PROTEIN, UNKNOWN FUNCTION
2g2p:C (THR23) to (VAL65) CRYSTAL STRUCTURE OF E.COLI TRANSTHYRETIN-RELATED PROTEIN WITH BOUND ZN AND BR | TRANSTHYRETIN, TRANSTHYRETIN-RELATED PROTEIN, UNKNOWN FUNCTION
3vb4:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH B4Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb4:B (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH B4Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb5:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH C4Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb5:B (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH C4Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb6:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH C6Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb7:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH M4Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vb7:B (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH M4Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1sn0:B (ALA29) to (GLU72) CRYSTAL STRUCTURE OF SEA BREAM TRANSTHYRETIN IN COMPLEX WITH THYROXINE AT 1.9A RESOLUTION | TRANSPORT PROTEIN
3i56:K (VAL74) to (VAL96) CO-CRYSTAL STRUCTURE OF TRIACETYLOLEANDOMCYIN BOUND TO THE LARGE RIBOSOMAL SUBUNIT | LARGE RIBOSOMAL SUBUNIT, TRIACETYLOLEANDOMCYIN, RIBONUCLEOPROTEIN, RIBOSOMAL PROTEIN, RNA-BINDING, RRNA- BINDING, TRNA-BINDING, METAL-BINDING, ZINC, ZINC-FINGER, ACETYLATION, RIBOSOME, RIBOSOME-ANTIBIOTIC COMPLEX
2vuj:A (GLY110) to (GLY157) ENVIRONMENTALLY ISOLATED GH11 XYLANASE | GH11, XYLANASE, HYDROLASE, GLYCOSIDASE
2vul:A (GLY110) to (GLY157) THERMOSTABLE MUTANT OF ENVIRONMENTALLY ISOLATED GH11 XYLANASE | GH11, XYLANASE, HYDROLASE, GLYCOSIDASE
2gct:B (GLN30) to (GLY69) STRUCTURE OF GAMMA-CHYMOTRYPSIN IN THE RANGE PH 2.0 TO PH 10.5 SUGGESTS THAT GAMMA-CHYMOTRYPSIN IS A COVALENT ACYL-ENZYME ADDUCT AT LOW PH | HYDROLASE, SERINE PROTEINASE, HYDROLASE-PEPTIDE COMPLEX
2vyn:A (ILE167) to (LYS247) STRUCTURE OF E.COLI GAPDH RAT SPERM GAPDH HETEROTETRAMER | OXIDOREDUCTASE, GAPDH, CONTRACEPTIVE, RAT SPERM, GLYCERALDEHYDE-3-PHOSPHATE, ALPHA CHLOROHYDRIN
3vhp:B (GLU152) to (PHE196) THE INSERTION MUTANT Y61GG OF TM CEL12A | JELLY ROLL, HYDROLASE, CELLULOSE
2gkv:E (ASP29) to (ALA68) CRYSTAL STRUCTURE OF THE SGPB:P14'-ALA32 OMTKY3-DEL(1-5) COMPLEX | BETA-BARRELS, CATALYTIC TRIAD, SUBSTRATE-BINDING REGION, REACTIVE-SITE LOOP, ALPHA-HELIX, BETA-SHEET, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1h4g:A (GLY113) to (SER160) OLIGOSACCHARIDE-BINDING TO FAMILY 11 XYLANASES: BOTH COVALENT INTERMEDIATE AND MUTANT-PRODUCT COMPLEXES DISPLAY 2,5B CONFORMATIONS AT THE ACTIVE-CENTRE | GLYCOSIDE HYDROLASE, XYLANASE, OLIGOSACCHARIDE, TRANSITION-STATE, INTERMEDIATE, MUTANT, BOAT CONFORMATION
1h4g:B (GLY113) to (SER160) OLIGOSACCHARIDE-BINDING TO FAMILY 11 XYLANASES: BOTH COVALENT INTERMEDIATE AND MUTANT-PRODUCT COMPLEXES DISPLAY 2,5B CONFORMATIONS AT THE ACTIVE-CENTRE | GLYCOSIDE HYDROLASE, XYLANASE, OLIGOSACCHARIDE, TRANSITION-STATE, INTERMEDIATE, MUTANT, BOAT CONFORMATION
1t6b:X (ASN268) to (ASN368) CRYSTAL STRUCTURE OF B. ANTHRACIS PROTECTIVE ANTIGEN COMPLEXED WITH HUMAN ANTHRAX TOXIN RECEPTOR | BACILLUS ANTHRACIS; ANTHRAX TOXIN; X-RAY CRYSTALLOGRAPHY, MEMBRANE PROTEIN-TOXIN COMPLEX
4l7b:B (VAL324) to (VAL369) STRUCTURE OF KEAP1 KELCH DOMAIN WITH (1S,2R)-2-{[(1S)-1-[(1,3-DIOXO-1, 3-DIHYDRO-2H-ISOINDOL-2-YL)METHYL]-3,4-DIHYDROISOQUINOLIN-2(1H)- YL]CARBONYL}CYCLOHEXANECARBOXYLIC ACID | STRESS SENSOR, KELCH DOMAIN, KELCH REPEAT MOTIF, BETA-PROPELLER, NRF2, PROTEIN-SMALL MOLECULE COMPLEX, TRANSCRIPTION-INHIBITOR COMPLEX
4zop:A (ASP434) to (PHE486) CO-CRYSTAL STRUCTURE OF LIPID KINASE PI3K ALPHA WITH A SELECTIVE PHOSPHATIDYLINOSITOL-3 KINASE ALPHA INHIBITOR | LIPID KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2w45:A (GLY378) to (PRO425) EPSTEIN-BARR VIRUS ALKALINE NUCLEASE | EXONUCLEASE, ENDONUCLEASE, GAMMA-HERPESVIRUS, EBV, BGLF5, DNASE, NUCLEASE, HYDROLASE, HERPESVIRUS, EPSTEIN-BARR VIRUS
2gt7:B (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PEPTIDASE AT PH 6.0 IN THE SPACE GROUP P21 | CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, LONG LOOP, ALPHA-HELICAL DOMAIN, DIMER, CATALYTIC DYAD, SPECIFICITY POCKETS, HYDROLASE
1tal:A (ILE31) to (GLY67) ALPHA-LYTIC PROTEASE AT 120 K (SINGLE STRUCTURE MODEL) | SERINE PROTEASE, LOW TEMPERATURE, HYDROLASE, SERINE PROTEINASE
2gz7:A (GLY109) to (TYR154) STRUCTURE-BASED DRUG DESIGN AND STRUCTURAL BIOLOGY STUDY OF NOVEL NONPEPTIDE INHIBITORS OF SARS-COV MAIN PROTEASE | SARS COV MAIN PROTEASE, HYDROLASE
2gz8:A (GLY109) to (TYR154) STRUCTURE-BASED DRUG DESIGN AND STRUCTURAL BIOLOGY STUDY OF NOVEL NONPEPTIDE INHIBITORS OF SARS-COV MAIN PROTEASE | SARS COV MAIN PROTEASE, HYDROLASE
3vnh:A (VAL3) to (VAL48) CRYSTAL STRUCTURE OF KEAP1 SOAKED WITH SYNTHETIC SMALL MOLECULAR | PROTEIN-SMALL MOLECULAR COMPLEX, BETA-PROPELLER, KELCH REPEAT MOTIF, SOAKING, STRESS SENSOR, SMALL MOLECULAR BINDING, PROTEIN BINDING
3iwm:B (GLN110) to (TYR154) THE OCTAMERIC SARS-COV MAIN PROTEASE | SARS-COV, MAIN PROTEASE, OCTAMER, ACTIVE CONFORMATION, HYDROLASE
4lk7:A (ALA64) to (TYR98) CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN LECA COMPLEXED WITH RESORUFIN-B-D-GALACTOPYRANOSIDE AT 1.76 A RESOLUTION | LECTIN FOLD, SUGAR BINDING PROTEIN, GALACTOSE
4zys:A (VAL56) to (ASN97) CRYSTAL STRUCTURE OF AN EXOTOXIN 6 (SAV0422) FROM STAPHYLOCOCCUS AUREUS SUBSP. AUREUS MU50 AT 2.25 A RESOLUTION | EXOTOXIN, SUPERANTIGEN-LIKE PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, SUGAR BINDING PROTEIN
4zys:B (VAL56) to (ASN97) CRYSTAL STRUCTURE OF AN EXOTOXIN 6 (SAV0422) FROM STAPHYLOCOCCUS AUREUS SUBSP. AUREUS MU50 AT 2.25 A RESOLUTION | EXOTOXIN, SUPERANTIGEN-LIKE PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, SUGAR BINDING PROTEIN
4ll9:A (THR134) to (GLY179) CRYSTAL STRUCTURE OF D3D4 DOMAIN OF THE LILRB1 MOLECULE | IG-LIKE DOMAIN, IMMUNE-MODULATORY MOLECULE, IMMUNE SYSTEM
4ll9:C (THR134) to (GLY179) CRYSTAL STRUCTURE OF D3D4 DOMAIN OF THE LILRB1 MOLECULE | IG-LIKE DOMAIN, IMMUNE-MODULATORY MOLECULE, IMMUNE SYSTEM
4zzt:A (GLY205) to (GLY240) GEOTRICHUM CANDIDUM CEL7A STRUCTURE COMPLEX WITH THIO- LINKED CELLOTRIOSE AT 1.56A | HYDROLASE, CELLOBIOHYDROLASE, THIO-LINKED CELLOTRIOSE
4zzv:A (GLY205) to (GLY240) GEOTRICHUM CANDIDUM CEL7A APO STRUCTURE AT 1.4A | HYDROLASE, CELLOBIOHYDROLASE
3vr2:D (LEU29) to (GLY74) CRYSTAL STRUCTURE OF NUCLEOTIDE-FREE A3B3 COMPLEX FROM ENTEROCOCCUS HIRAE V-ATPASE [EA3B3] | V-ATPASE, ENTEROCOCCUS HIRAE, ROTARY MOTOR, P-LOOP, HYDROLASE, NA(+)- ATPASE, ATP BINDING
3vr2:F (LEU29) to (PHE72) CRYSTAL STRUCTURE OF NUCLEOTIDE-FREE A3B3 COMPLEX FROM ENTEROCOCCUS HIRAE V-ATPASE [EA3B3] | V-ATPASE, ENTEROCOCCUS HIRAE, ROTARY MOTOR, P-LOOP, HYDROLASE, NA(+)- ATPASE, ATP BINDING
3vr3:E (LEU29) to (GLY74) CRYSTAL STRUCTURE OF AMP-PNP BOUND A3B3 COMPLEX FROM ENTEROCOCCUS HIRAE V-ATPASE [BA3B3] | V-ATPASE, ENTEROCOCCUS HIRAE, ROTARY MOTOR, P-LOOP, HYDROLASE, NA(+)- ATPASE, ATP BINDING
3vr3:F (LEU29) to (GLY74) CRYSTAL STRUCTURE OF AMP-PNP BOUND A3B3 COMPLEX FROM ENTEROCOCCUS HIRAE V-ATPASE [BA3B3] | V-ATPASE, ENTEROCOCCUS HIRAE, ROTARY MOTOR, P-LOOP, HYDROLASE, NA(+)- ATPASE, ATP BINDING
5a0d:C (LYS102) to (PHE161) N-TERMINAL THIOESTER DOMAIN OF SURFACE PROTEIN FROM CLOSTRIDIUM PERFRINGENS, CYS138ALA MUTANT | CELL ADHESION, SURFACE-ASSOCIATED PROTEIN, GRAM-POSITIVE, ADHESIN, INTERNAL THIOESTER, THIOESTER DOMAIN
3vr4:F (LEU29) to (PHE72) CRYSTAL STRUCTURE OF ENTEROCOCCUS HIRAE V1-ATPASE [EV1] | V-ATPASE, ENTEROCOCCUS HIRAE, ROTARY MOTOR, P-LOOP, HYDROLASE, NA(+)- ATPASE, ATP BINDING
5a0g:A (THR101) to (PHE161) N-TERMINAL THIOESTER DOMAIN OF SURFACE PROTEIN FROM CLOSTRIDIUM PERFRINGENS | CELL ADHESION, SURFACE-ASSOCIATED PROTEIN, GRAM-POSITIVE, ADHESIN, INTERNAL THIOESTER, THIOESTER DOMAIN
5a0g:B (SER100) to (PHE161) N-TERMINAL THIOESTER DOMAIN OF SURFACE PROTEIN FROM CLOSTRIDIUM PERFRINGENS | CELL ADHESION, SURFACE-ASSOCIATED PROTEIN, GRAM-POSITIVE, ADHESIN, INTERNAL THIOESTER, THIOESTER DOMAIN
5a0g:C (THR101) to (PHE161) N-TERMINAL THIOESTER DOMAIN OF SURFACE PROTEIN FROM CLOSTRIDIUM PERFRINGENS | CELL ADHESION, SURFACE-ASSOCIATED PROTEIN, GRAM-POSITIVE, ADHESIN, INTERNAL THIOESTER, THIOESTER DOMAIN
5a0g:D (THR101) to (PHE161) N-TERMINAL THIOESTER DOMAIN OF SURFACE PROTEIN FROM CLOSTRIDIUM PERFRINGENS | CELL ADHESION, SURFACE-ASSOCIATED PROTEIN, GRAM-POSITIVE, ADHESIN, INTERNAL THIOESTER, THIOESTER DOMAIN
5a0g:E (THR101) to (PHE161) N-TERMINAL THIOESTER DOMAIN OF SURFACE PROTEIN FROM CLOSTRIDIUM PERFRINGENS | CELL ADHESION, SURFACE-ASSOCIATED PROTEIN, GRAM-POSITIVE, ADHESIN, INTERNAL THIOESTER, THIOESTER DOMAIN
5a0g:F (THR101) to (PHE161) N-TERMINAL THIOESTER DOMAIN OF SURFACE PROTEIN FROM CLOSTRIDIUM PERFRINGENS | CELL ADHESION, SURFACE-ASSOCIATED PROTEIN, GRAM-POSITIVE, ADHESIN, INTERNAL THIOESTER, THIOESTER DOMAIN
3vr5:F (LEU29) to (PHE72) CRYSTAL STRUCTURE OF NUCLEOTIDE-FREE ENTEROCOCCUS HIRAE V1-ATPASE [EV1(L)] | V-ATPASE, ENTEROCOCCUS HIRAE, ROTARY MOTOR, P-LOOP, HYDROLASE, NA(+)- ATPASE, ATP BINDING
2hld:E (ASN35) to (ASP78) CRYSTAL STRUCTURE OF YEAST MITOCHONDRIAL F1-ATPASE | ATP PHOSPHORYLASE (H+ TRANSPORTING), ATP SYNTHASE, F1FO, F1-ATPASE, HYDROLASE
1twg:H (ILE9) to (THR56) RNA POLYMERASE II COMPLEXED WITH CTP | TRANSCRIPTION, MRNA, MULTIPROTEIN COMPLEX, MOLECULAR MACHINE, ZINC MOTIFS
2hnt:C (GLN30) to (GLY69) CRYSTALLOGRAPHIC STRUCTURE OF HUMAN GAMMA-THROMBIN | SERINE PROTEASE
2hob:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE WITH AUTHENTIC N AND C- TERMINI IN COMPLEX WITH A MICHAEL ACCEPTOR N3 | SARS-COV, MAIN PROTEASE, MICHAEL ACCEPTOR N3, VIRAL PROTEIN
4lo6:B (ASN404) to (ASP451) HA70-ALPHA2,6-SIALC | PROGENITOR TOXIN COMPLEX, BOTULINUM NEUROTOXIN, BOTULISM, NEUROTOXIN ASSOCIATED PROTEIN, HEMAGGLUTININ, CARBOHYDRATE/SUGAR BINDING, SECRETED PROTEIN, PROTEIN TRANSPORT
4lp7:A (THR54) to (THR114) CRYSTAL STRUCTURE OF THE HUMAN METAPNEUMOVIRUS MATRIX PROTEIN | TWISTED BETA SANDWICH, VIRAL MATRIX, LIPID BINDING, CALCIUM BINDING PROTEIN
3vzl:B (THR93) to (THR147) CRYSTAL STRUCTURE OF THE BACILLUS CIRCULANS ENDO-BETA-(1,4)-XYLANASE (BCX) N35H MUTANT | XYLANASE, GH-11 GLYCOSIDE HYDROLASE, HYDROLASE
2wpd:F (ASN35) to (ASP78) THE MG.ADP INHIBITED STATE OF THE YEAST F1C10 ATP SYNTHASE | ATP PHOSPHORYLASE (H+ TRANSPORTING), ATP-BINDING, CENTRAL STALK, HYDROLASE, ATP SYNTHESIS, PHOSPHOPROTEIN, MEMBRANE PROTEIN, LIPID-BINDING, ION TRANSPORT, NUCLEOTIDE-BINDING, HYDROGEN ION TRANSPORT
1u6d:X (VAL324) to (VAL369) CRYSTAL STRUCTURE OF THE KELCH DOMAIN OF HUMAN KEAP1 | BETA-PROPELLER, KELCH REPEAT MOTIF, PROTEIN BINDING
3w3a:D (GLY30) to (SER74) CRYSTAL STRUCTURE OF V1-ATPASE AT 3.9 ANGSTROM RESOLUTION | ATP SYNTHESIS, HYDROGEN ION TRANSPORT, NUCLEOTIDE-BINDING, CATALYTIC DOMAIN, MOLECULAR MOTOR PROTEINS, QUATERNARY, PROTON-TRANSLOCATING ATPASES, THERMUS THERMOPHILUS, VACUOLAR PROTON-TRANSLOCATING ATPASES, HYDROLYSIS, HYDROLASE
2hz0:A (ASN358) to (GLY390) ABL KINASE DOMAIN IN COMPLEX WITH NVP-AEG082 | TYROSINE KINASE, TRANSFERASE
2wss:E (ASN34) to (ASP77) THE STRUCTURE OF THE MEMBRANE EXTRINSIC REGION OF BOVINE ATP SYNTHASE | HYDROGEN ION TRANSPORT, ATP SYNTHESIS, PHOSPHOPROTEIN, UBL CONJUGATION, TRANSIT PEPTIDE, NUCLEOTIDE-BINDING, ACETYLATION, ATP-BINDING, ION TRANSPORT, MITOCHONDRION, PYRROLIDONE CARBOXYLIC ACID, HYDROLASE, TRANSPORT
2wss:K (GLU51) to (GLY92) THE STRUCTURE OF THE MEMBRANE EXTRINSIC REGION OF BOVINE ATP SYNTHASE | HYDROGEN ION TRANSPORT, ATP SYNTHESIS, PHOSPHOPROTEIN, UBL CONJUGATION, TRANSIT PEPTIDE, NUCLEOTIDE-BINDING, ACETYLATION, ATP-BINDING, ION TRANSPORT, MITOCHONDRION, PYRROLIDONE CARBOXYLIC ACID, HYDROLASE, TRANSPORT
2wss:N (ASN34) to (ASP77) THE STRUCTURE OF THE MEMBRANE EXTRINSIC REGION OF BOVINE ATP SYNTHASE | HYDROGEN ION TRANSPORT, ATP SYNTHESIS, PHOSPHOPROTEIN, UBL CONJUGATION, TRANSIT PEPTIDE, NUCLEOTIDE-BINDING, ACETYLATION, ATP-BINDING, ION TRANSPORT, MITOCHONDRION, PYRROLIDONE CARBOXYLIC ACID, HYDROLASE, TRANSPORT
2wst:C (SER231) to (GLY286) HEAD DOMAIN OF PORCINE ADENOVIRUS TYPE 4 NADC-1 ISOLATE FIBRE | VIRAL PROTEIN
1ueb:B (GLU266) to (ASP313) CRYSTAL STRUCTURE OF TRANSLATION ELONGATION FACTOR P FROM THERMUS THERMOPHILUS HB8 | BETA BARREL, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, RNA BINDING PROTEIN
2i2l:C (ILE70) to (VAL119) X-RAY CRYSTAL STRUCTURE OF PROTEIN YOPX FROM BACILLUS SUBTILIS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR411. | NESG, SR411, YOPX, O34401, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, UNKNOWN FUNCTION
1uj1:B (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
1uk3:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) AT PH7.6 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
1iqw:H (VAL93) to (SER120) CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF THE MOUSE ANTI- HUMAN FAS ANTIBODY HFE7A | IMMUNOGLOBULIN, FAB, ANTI_FAS, AGONISTIC ANTIBODY, APOPTOSIS, IMMUNE SYSTEM
1unn:A (LEU33) to (PRO71) COMPLEX OF BETA-CLAMP PROCESSIVITY FACTOR AND LITTLE FINGER DOMAIN OF POLIV | BETA-CLAMP, POL IV, TRANSLESION, TRANSFERASE, DNA-DIRECTED DNA POLYMERASE, DNA REPLICATION
2wxj:A (ASP430) to (PHE485) THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH INK654. | TRANSFERASE, PHOSPHOPROTEIN, ISOFORM-SPECIFIC INHIBITORS, CANCER, NUCLEOTIDE-BINDING
2wxk:A (ASP430) to (PHE485) THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH INK666. | TRANSFERASE, PHOSPHOPROTEIN, ISOFORM-SPECIFIC INHIBITORS, CANCER
2wxl:A (ASP430) to (PHE485) THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH ZSTK474. | TRANSFERASE, PHOSPHOPROTEIN, ISOFORM-SPECIFIC INHIBITORS, CANCER
2wxm:A (ASP430) to (PHE485) THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH DL06. | TRANSFERASE, PHOSPHOPROTEIN, ISOFORM-SPECIFIC INHIBITORS, CANCER
2wxn:A (ASP430) to (PHE485) THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH DL07. | TRANSFERASE, PHOSPHOPROTEIN, ISOFORM-SPECIFIC INHIBITORS, CANCER
2wxp:A (ASP430) to (PHE485) THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH GDC-0941. | TRANSFERASE, PHOSPHOPROTEIN, ISOFORM-SPECIFIC INHIBITORS, CANCER
2wxr:A (ASP430) to (PHE485) THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA. | TRANSFERASE, PHOSPHOPROTEIN, ISOFORM-SPECIFIC INHIBITORS, CANCER
2wz8:A (ASN18) to (ASN53) FAMILY 35 CARBOHYDRATE BINDING MODULE FROM CLOSTRIDIUM THERMOCELLUM | SUGAR BINDING PROTEIN
2igl:A (THR46) to (VAL88) CRYSTAL STRUCTURE OF E. COLI YEDX, A TRANSTHYRETIN RELATED PROTEIN | TRANSTHYRETIN, TRANSTHYRETIN RELATED PROTEIN, UNKNOWN FUNCTION
2igl:B (THR46) to (VAL88) CRYSTAL STRUCTURE OF E. COLI YEDX, A TRANSTHYRETIN RELATED PROTEIN | TRANSTHYRETIN, TRANSTHYRETIN RELATED PROTEIN, UNKNOWN FUNCTION
2igl:C (THR46) to (VAL88) CRYSTAL STRUCTURE OF E. COLI YEDX, A TRANSTHYRETIN RELATED PROTEIN | TRANSTHYRETIN, TRANSTHYRETIN RELATED PROTEIN, UNKNOWN FUNCTION
2igl:D (THR46) to (VAL88) CRYSTAL STRUCTURE OF E. COLI YEDX, A TRANSTHYRETIN RELATED PROTEIN | TRANSTHYRETIN, TRANSTHYRETIN RELATED PROTEIN, UNKNOWN FUNCTION
4mbc:A (SER132) to (PHE176) STRUCTURE OF STREPTOCOCCUS PNEUMONIA PARE IN COMPLEX WITH AZ13053807 | ATP BINDING, STRUCTURE-BASED DRUG DESIGN, ANTIMICROBIAL, ISOMERASE- ISOMERASE INHIBITOR COMPLEX
3wdz:A (ILE328) to (VAL369) CRYSTAL STRUCTURE OF KEAP1 IN COMPLEX WITH PHOSPHORYLATED P62 | KELCH REPEAT, TRANSCRIPTION, P62, NUCLEUS
3j2w:L (GLY3191) to (ASP3225) ELECTRON CRYO-MICROSCOPY OF CHIKUNGUNYA VIRUS | E1-E2 GLYCOPROTEIN, NUCLEOCAPSID PROTEIN, TRANSMEMBRANE HELIX, VIRUS
4mds:A (GLY109) to (TYR154) DISCOVERY OF N-(BENZO[1,2,3]TRIAZOL-1-YL)-N-(BENZYL)ACETAMIDO)PHENYL) CARBOXAMIDES AS SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS (SARS- COV) 3CLPRO INHIBITORS: IDENTIFICATION OF ML300 AND NON-COVALENT NANOMOLAR INHIBITORS WITH AN INDUCED-FIT BINDING | CHYMOTRYPSIN-LIKE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3win:E (ASN404) to (ASP451) CLOSTRIDIUM BOTULINUM HEMAGGLUTININ | BACTERIAL PATHOGENESIS, BACTERIAL TOXINS, CARBOHYDRATE-BINDING PROTEIN, E-CADHERIN, EPITHELIAL CELL, PROTEIN COMPLEXES, BOTULINUM TOXIN, HEMAGGLUTININ, BETA-TREFOIL, TOXIN
1v1o:B (LYS45) to (GLY82) STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN 7 | VIRULENCE FACTOR, ANTIGEN PRESENTING CELL, SECRETED PROTEIN, STAPHYLOCOCCAL EXOTOXIN 1, SET1
1v4y:A (ASP428) to (ASN459) THE FUNCTIONAL ROLE OF THE BINUCLEAR METAL CENTER IN D- AMINOACYLASE. ONE-METAL ACTIVATION AND SECOND-METAL ATTENUATION | TIM BARREL, BETA BARREL, INSERTION, HYDROLASE
1v51:A (ASP428) to (ASN459) THE FUNCTIONAL ROLE OF THE BINUCLEAR METAL CENTER IN D- AMINOACYLASE. ONE-METAL ACTIVATION AND SECOND-METAL ATTENUATION | TIM BARREL, BETA BARREL, INSERTION, HYDROLASE
3wnp:A (GLY468) to (HIS511) D308A, F268V, D469Y, A513V, AND Y515S QUINTUPLE MUTANT OF BACILLUS CIRCULANS T-3040 CYCLOISOMALTOOLIGOSACCHARIDE GLUCANOTRANSFERASE COMPLEXED WITH ISOMALTOUNDECAOSE | C2 TYPE IMMUNOGLOBULIN FOLD, (BETA/ALPHA)8-BARREL, BETA-JELLY ROLL, GREEK KEY, GLYCOSIDE HYDROLASE, ALPHA-1,6-GLUCAN, TRANSFERASE
3wnp:B (GLY468) to (HIS511) D308A, F268V, D469Y, A513V, AND Y515S QUINTUPLE MUTANT OF BACILLUS CIRCULANS T-3040 CYCLOISOMALTOOLIGOSACCHARIDE GLUCANOTRANSFERASE COMPLEXED WITH ISOMALTOUNDECAOSE | C2 TYPE IMMUNOGLOBULIN FOLD, (BETA/ALPHA)8-BARREL, BETA-JELLY ROLL, GREEK KEY, GLYCOSIDE HYDROLASE, ALPHA-1,6-GLUCAN, TRANSFERASE
5amp:A (GLY205) to (GLY240) GEOTRICHUM CANDIDUM CEL7A APO STRUCTURE AT 2.1A | HYDROLASE, CELLOBIOHYDROLASE
2xcn:B (GLU32) to (SER66) CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR | HYDROLASE, SERINE PROTEASE
3wq7:B (LYS215) to (PRO260) NEW CRYSTAL FORM OF THE HYPERTHERMOPHILIC FAMILY 12 ENDO-CELLULASE FROM PYROCOCCUS FURIOSUS | BETA-JELLY ROLL, GLYCOSIDE HYDROLASE, HYDROLASE
4mqa:A (GLN45) to (LEU90) HUMAN BETA-TRYPTASE CO-CRYSTAL STRUCTURE WITH {(1,1,3,3- TETRAMETHYLDISILOXANE-1,3-DIYL)BIS[5-(METHYLSULFANYL)BENZENE-3,1- DIYL]}BIS({4-[3-(AMINOMETHYL)PHENYL]PIPERIDIN-1-YL}METHANONE) | COFERON, ALPHA-HYDROXYKETONE, SMALL MOLECULE INHIBITOR, DRUG DISCOVERY, SELF-ASSEMBLY, CRYSTAL CATALYSIS, SILANOL, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4mvj:C (ILE169) to (LYS249) 2.85 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF GLYCERALDEHYDE 3- PHOSPHATE DEHYDROGENASE A (GAPA) FROM ESCHERICHIA COLI MODIFIED BY ACETYL PHOSPHATE. | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, N-TERMINAL NAD BINDING DOMAIN, OXIDOREDUCTASE
4mvj:D (ILE169) to (LYS249) 2.85 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF GLYCERALDEHYDE 3- PHOSPHATE DEHYDROGENASE A (GAPA) FROM ESCHERICHIA COLI MODIFIED BY ACETYL PHOSPHATE. | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, N-TERMINAL NAD BINDING DOMAIN, OXIDOREDUCTASE
4mvj:E (ILE169) to (VAL245) 2.85 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF GLYCERALDEHYDE 3- PHOSPHATE DEHYDROGENASE A (GAPA) FROM ESCHERICHIA COLI MODIFIED BY ACETYL PHOSPHATE. | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, N-TERMINAL NAD BINDING DOMAIN, OXIDOREDUCTASE
4mvj:H (ILE169) to (LYS249) 2.85 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF GLYCERALDEHYDE 3- PHOSPHATE DEHYDROGENASE A (GAPA) FROM ESCHERICHIA COLI MODIFIED BY ACETYL PHOSPHATE. | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, N-TERMINAL NAD BINDING DOMAIN, OXIDOREDUCTASE
4mvj:P (ILE169) to (VAL245) 2.85 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF GLYCERALDEHYDE 3- PHOSPHATE DEHYDROGENASE A (GAPA) FROM ESCHERICHIA COLI MODIFIED BY ACETYL PHOSPHATE. | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, N-TERMINAL NAD BINDING DOMAIN, OXIDOREDUCTASE
4mvn:B (SER17) to (ALA53) CRYSTAL STRUCTURE OF THE STAPHYLOCOCCAL SERINE PROTEASE SPLA IN COMPLEX WITH A SPECIFIC PHOSPHONATE INHIBITOR | CHYMOTRYPSIN-LIKE FOLD, SERINE ENDOPEPTIDASE, EXTRACELLULAR STAPHYLOCOCCAL PROTEASES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2xk1:C (GLY165) to (GLY215) CRYSTAL STRUCTURE OF A COMPLEX BETWEEN ACTINOMADURA R39 DD- PEPTIDASE AND A BORONATE INHIBITOR | HYDROLASE, PEPTIDOGLYCAN
2xnd:C (GLU51) to (ARG90) CRYSTAL STRUCTURE OF BOVINE F1-C8 SUB-COMPLEX OF ATP SYNTHASE | ATP PHOSPHORYLASE (H+ TRANSPORTING), ATP SYNTHESIS, F1FO ATP SYNTHASE, HYDROLASE, ION TRANSPORT, P-LOOP
2xok:D (ASN35) to (ASP78) REFINED STRUCTURE OF YEAST F1C10 ATPASE COMPLEX TO 3 A RESOLUTION | HYDROLASE, ATP-BINDING, F(O), F(1), ATP SYNTHASE, MITOCHONDRIA, INNER MEMBRANE, TRANSMEMBRANE
2xok:E (ASN35) to (ASP78) REFINED STRUCTURE OF YEAST F1C10 ATPASE COMPLEX TO 3 A RESOLUTION | HYDROLASE, ATP-BINDING, F(O), F(1), ATP SYNTHASE, MITOCHONDRIA, INNER MEMBRANE, TRANSMEMBRANE
4n1b:B (LEU327) to (VAL369) STRUCTURE OF KEAP1 KELCH DOMAIN WITH(1S,2R)-2-[(1S)-1-[(1-OXO-2,3- DIHYDRO-1H-ISOINDOL-2-YL)METHYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-2- CARBONYL]CYCLOHEXANE-1-CARBOXYLIC ACID | REPLACEMENT SOAKING, STRESS SENSOR, SMALL MOLECULAR BINDING, KELCH DOMAIN, KELCH REPEAT MOTIF, BETA-PROPELLER, NRF2, PROTEIN-SMALL MOLECULE COMPLEX, CYTOSOL, TRANSCRIPTION-INHIBITOR COMPLEX, CYTOSOL,
4n1b:C (ILE328) to (VAL369) STRUCTURE OF KEAP1 KELCH DOMAIN WITH(1S,2R)-2-[(1S)-1-[(1-OXO-2,3- DIHYDRO-1H-ISOINDOL-2-YL)METHYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-2- CARBONYL]CYCLOHEXANE-1-CARBOXYLIC ACID | REPLACEMENT SOAKING, STRESS SENSOR, SMALL MOLECULAR BINDING, KELCH DOMAIN, KELCH REPEAT MOTIF, BETA-PROPELLER, NRF2, PROTEIN-SMALL MOLECULE COMPLEX, CYTOSOL, TRANSCRIPTION-INHIBITOR COMPLEX, CYTOSOL,
3j9u:A (LEU48) to (ARG87) YEAST V-ATPASE STATE 2 | V-ATPASE, V-TYPE ATPASE, VACUOLAR-TYPE ATPASE, PROTON PUMP, HYDROLASE
5b6o:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF MS8104 | HYDROLASE, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
5b6o:B (GLY109) to (TYR154) CRYSTAL STRUCTURE OF MS8104 | HYDROLASE, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
3zg0:B (THR423) to (LEU455) CRYSTAL STRUCTURE OF CEFTAROLINE ACYL-PBP2A FROM MRSA WITH NON-COVALENTLY BOUND CEFTAROLINE AND MURAMIC ACID AT ALLOSTERIC SITE OBTAINED BY COCRYSTALLIZATION | HYDROLASE, MRSA, ALLOSTERIC SITE, B-LACTAM ANTIBIOTICS
4nam:A (LEU20) to (ILE64) 1.7A STRUCTURE OF 5-FLUORO TRYPTOPHAN LABELED PROTECTIVE ANTIGEN (W206Y) | ANTHRAX, TOXIN, 5-FLUOROTRYPTOPHAN, PORE
4nam:A (ASN268) to (ALA362) 1.7A STRUCTURE OF 5-FLUORO TRYPTOPHAN LABELED PROTECTIVE ANTIGEN (W206Y) | ANTHRAX, TOXIN, 5-FLUOROTRYPTOPHAN, PORE
2xwj:I (GLN471) to (GLY517) CRYSTAL STRUCTURE OF COMPLEMENT C3B IN COMPLEX WITH FACTOR B | IMMUNE SYSTEM, PRO-CONVERTASE, HYDROLASE, SERINE PROTEASE, CONFORMATIONAL CHANGES, ALTERNATIVE PATHWAY
2xwj:J (ALA472) to (GLY517) CRYSTAL STRUCTURE OF COMPLEMENT C3B IN COMPLEX WITH FACTOR B | IMMUNE SYSTEM, PRO-CONVERTASE, HYDROLASE, SERINE PROTEASE, CONFORMATIONAL CHANGES, ALTERNATIVE PATHWAY
2xwj:K (ALA472) to (GLY517) CRYSTAL STRUCTURE OF COMPLEMENT C3B IN COMPLEX WITH FACTOR B | IMMUNE SYSTEM, PRO-CONVERTASE, HYDROLASE, SERINE PROTEASE, CONFORMATIONAL CHANGES, ALTERNATIVE PATHWAY
2xwj:L (ALA472) to (GLY517) CRYSTAL STRUCTURE OF COMPLEMENT C3B IN COMPLEX WITH FACTOR B | IMMUNE SYSTEM, PRO-CONVERTASE, HYDROLASE, SERINE PROTEASE, CONFORMATIONAL CHANGES, ALTERNATIVE PATHWAY
1k3r:A (GLN107) to (SER141) CRYSTAL STRUCTURE OF THE METHYLTRANSFERASE WITH A KNOT FROM METHANOBACTERIUM THERMOAUTOTROPHICUM | BETA BARREL, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
4nco:E (VAL127) to (ASN197) CRYSTAL STRUCTURE OF THE BG505 SOSIP GP140 HIV-1 ENV TRIMER IN COMPLEX WITH THE BROADLY NEUTRALIZING FAB PGT122 | TYPE-1 MEMBRANE FUSION GLYCOPROTEIN TRIMER, HIV-1 ENVELOPE, GP120, GP41, MEMBRANE FUSION, VIRAL ENTRY, CD4, CCR5/CXCR4, BROADLY NEUTRALIZING ANTIBODIES, VIRAL SURFACE, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
4nco:I (VAL127) to (ASN197) CRYSTAL STRUCTURE OF THE BG505 SOSIP GP140 HIV-1 ENV TRIMER IN COMPLEX WITH THE BROADLY NEUTRALIZING FAB PGT122 | TYPE-1 MEMBRANE FUSION GLYCOPROTEIN TRIMER, HIV-1 ENVELOPE, GP120, GP41, MEMBRANE FUSION, VIRAL ENTRY, CD4, CCR5/CXCR4, BROADLY NEUTRALIZING ANTIBODIES, VIRAL SURFACE, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
1wcq:A (GLU584) to (SER628) MUTAGENESIS OF THE NUCLEOPHILIC TYROSINE IN A BACTERIAL SIALIDASE TO PHENYLALANINE. | HYDROLASE, SIALIDASE, MICROMONOSPORA VIRIDIFACIENS, HYDROLASE NEURAMINIDASE, GLYCOSIDASE
3zim:A (ASP434) to (PHE486) DISCOVERY OF A POTENT AND ISOFORM-SELECTIVE TARGETED COVALENT INHIBITOR OF THE LIPID KINASE PI3KALPHA | TRANSFERASE
1k83:H (ILE9) to (ALA60) CRYSTAL STRUCTURE OF YEAST RNA POLYMERASE II COMPLEXED WITH THE INHIBITOR ALPHA AMANITIN | TRANSCRIPTION-TOXIN COMPLEX, ALPHA AMANITIN, TOXIN, INHIBITOR, POLYMERASE, TRANSFERASE, DNA BINDING, ZINC-FINGER, PHOSPHOPROTEIN, TRANSCRIPTION, UBL TRANSCRIPTION-TOXIN COMPLEX
1whi:A (VAL63) to (VAL85) RIBOSOMAL PROTEIN L14 | RIBOSOMAL PROTEIN, RRNA-BINDING
1wka:A (ILE226) to (THR272) STRUCTURAL BASIS FOR NON-COGNATE AMINO ACID DISCRIMINATION BY THE VALYL-TRNA SYNTHETASE EDITING DOMAIN | EDITING, CP1, VALYL-TRNA SYNTHETASE, FIDELITY, THERMUS THRMOPHILUS, TRANSLATION, AMINO ACID, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LIGASE
1wof:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR N1 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
1wof:B (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR N1 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
2y55:B (THR167) to (ILE210) UNEXPECTED TRICOVALENT BINDING MODE OF BORONIC ACIDS WITHIN THE ACTIVE SITE OF A PENICILLIN BINDING PROTEIN | HYDROLASE-INHIBITOR COMPLEX, PEPTIDOGLYCAN, HYDROLASE
2lpr:A (ILE29) to (ILE80) STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3zry:D (ASN35) to (ASP78) ROTOR ARCHITECTURE IN THE F(1)-C(10)-RING COMPLEX OF THE YEAST F-ATP SYNTHASE | HYDROLASE, ATP-BINDING, F(1)-F(O)ATP SYNTHASE, MITOCHONDRIA, MOLECULAR MOTOR, CENTRAL STALK, MEMBRANE PROTEIN, C-RING
3zry:E (ASN35) to (ASP78) ROTOR ARCHITECTURE IN THE F(1)-C(10)-RING COMPLEX OF THE YEAST F-ATP SYNTHASE | HYDROLASE, ATP-BINDING, F(1)-F(O)ATP SYNTHASE, MITOCHONDRIA, MOLECULAR MOTOR, CENTRAL STALK, MEMBRANE PROTEIN, C-RING
3zry:F (ASN35) to (GLY80) ROTOR ARCHITECTURE IN THE F(1)-C(10)-RING COMPLEX OF THE YEAST F-ATP SYNTHASE | HYDROLASE, ATP-BINDING, F(1)-F(O)ATP SYNTHASE, MITOCHONDRIA, MOLECULAR MOTOR, CENTRAL STALK, MEMBRANE PROTEIN, C-RING
5c44:A (MET146) to (LYS176) CRYSTAL STRUCTURE OF A TRANSCRIBING RNA POLYMERASE II COMPLEX REVEALS A COMPLETE TRANSCRIPTION BUBBLE | PROTEIN-DNA COMPLEX, RNA POLYERMASE II, TRANSCRIBING COMPLEX, TRANSFERASE-DNA-RNA COMPLEX
5c59:D (GLN104) to (PRO159) CRYSTAL STRUCTURE OF THE PERIPLASMIC REGION OF MACB FROM E. COLI | EFFLUX PUMP, ABC TRANSPORTER, HYDROLASE
5c5n:A (GLN110) to (TYR154) STRUCTURE OF SARS-3CL PROTEASE COMPLEX WITH A PHENYL-BETA-ALANYL (R, S)-N-DECALIN TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDRASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5c70:B (VAL239) to (GLY294) THE STRUCTURE OF ASPERGILLUS ORYZAE BETA-GLUCURONIDASE | BETA-GLUCURONIDASE, HYDROLASE
4o1n:A (VAL32) to (ASN73) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN SAOUHSC_00383 | OLIGOSACCHARIDE-BINDING, BETA-GRASP DOMAIN, SUGAR BINDING PROTEIN
4o1n:B (THR33) to (ASN73) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN SAOUHSC_00383 | OLIGOSACCHARIDE-BINDING, BETA-GRASP DOMAIN, SUGAR BINDING PROTEIN
4o1n:C (VAL32) to (ASN73) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN SAOUHSC_00383 | OLIGOSACCHARIDE-BINDING, BETA-GRASP DOMAIN, SUGAR BINDING PROTEIN
4o1n:D (THR33) to (ASN73) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN SAOUHSC_00383 | OLIGOSACCHARIDE-BINDING, BETA-GRASP DOMAIN, SUGAR BINDING PROTEIN
4o1n:E (VAL32) to (ASN73) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN SAOUHSC_00383 | OLIGOSACCHARIDE-BINDING, BETA-GRASP DOMAIN, SUGAR BINDING PROTEIN
2nqy:A (GLY113) to (SER160) CRYSTAL STRUCTURE OF ALKALINE THERMOPHLIC XYLANASE FROM BACILLUS SP. (NCL 86-6-10) WITH COMPLEX XYLOTRIOSE: XYLOTRIOSE CLEAVED TO XYLOBIOSE AND XYLOSE | ALKALINE XYLANASE, ACTIVE SITE RESIDUES, THREE-DIMENTIONAL STRUCTURE, XYLOTRISE, XYLOBIOSE, XYLOSE, HYDROLASE
2nqy:B (GLY113) to (SER160) CRYSTAL STRUCTURE OF ALKALINE THERMOPHLIC XYLANASE FROM BACILLUS SP. (NCL 86-6-10) WITH COMPLEX XYLOTRIOSE: XYLOTRIOSE CLEAVED TO XYLOBIOSE AND XYLOSE | ALKALINE XYLANASE, ACTIVE SITE RESIDUES, THREE-DIMENTIONAL STRUCTURE, XYLOTRISE, XYLOBIOSE, XYLOSE, HYDROLASE
4o59:P (VAL168) to (LYS248) CO-ENZYME INDUCED CONFORMATIONAL CHANGES IN BOVINE EYE GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE | OXIDOREDUCTASE, TRANSFERASE
4o59:R (VAL168) to (LYS248) CO-ENZYME INDUCED CONFORMATIONAL CHANGES IN BOVINE EYE GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE | OXIDOREDUCTASE, TRANSFERASE
2nu0:E (ASP29) to (ALA68) MOLECULAR STRUCTURES OF THE COMPLEXES OF SGPB WITH OMTKY3 AROMATIC P1 VARIANTS TRP18I, HIS18I, PHE18I, AND TYR18I | ENZYME-INHIBITOR COMPLEX, AROMATIC P1 RESIDUE, HYDROLASE
2nu1:E (ASP29) to (ALA68) MOLECULAR STRUCTURES OF THE COMPLEXES OF SGPB WITH OMTKY3 AROMATIC P1 VARIANTS TRP18I, HIS18I, PHE18I AND TYR18I | ENZYME-INHIBITOR COMPLEX, AROMATIC P1 RESIDUE, HYDROLASE
2nu2:E (ASP29) to (ALA68) ACCOMMODATION OF POSITIVELY-CHARGED RESIDUES IN A HYDROPHOBIC SPECIFICITY POCKET: CRYSTAL STRUCTURES OF SGPB IN COMPLEX WITH OMTKY3 VARIANTS LYS18I AND ARG18I | ENZYME-INHIBITOR COMPLEX, CHARGED P1 RESIDUE, HYDROLASE
2nu3:E (ASP29) to (ALA68) ACCOMMODATION OF POSITIVELY-CHARGED RESIDUES IN A HYDROPHOBIC SPECIFICITY POCKET: CRYSTAL STRUCTURES OF SGPB IN COMPLEX WITH OMTKY3 VARIANTS LYS18I AND ARG18I | ENZYME-INHIBITOR COMPLEX, CHARGED P1 RESIDUE, HYDROLASE
2nu4:E (ASP29) to (ALA68) ACCOMMODATION OF POSITIVELY-CHARGED RESIDUES IN A HYDROPHOBIC SPECIFICITY POCKET: CRYSTAL STRUCTURES OF SGPB IN COMPLEX WITH OMTKY3 VARIANTS LYS18I AND ARG18I | ENZYME-INHIBITOR COMPLEX, CHARGED P1 RESIDUE, HYDROLASE
4o63:P (VAL168) to (LYS248) CO-ENZYME INDUCED CONFORMATIONAL CHANGES IN BOVINE EYE GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE | OXIDOREDUCTASE, TRANSFERASE
3jv4:B (ILE278) to (LEU331) CRYSTAL STRUCTURE OF THE DIMERIZATION DOMAINS P50 AND RELB | NF-KB PROTEIN, HETERODIMER, RELB AND P50, ACTIVATOR, NUCLEUS, PHOSPHOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, ANK REPEAT, APOPTOSIS, DNA-BINDING, S-NITROSYLATION
5ce1:A (GLN177) to (GLY220) CRYSTAL STRUCTURE OF SERINE PROTEASE HEPSIN IN COMPLEX WITH INHIBITOR | SERINE PROTEASE, HEPSIN, PROSTATE CANCER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4o9x:A (SER486) to (ALA535) CRYSTAL STRUCTURE OF TCDB2-TCCC3 | BETA SHEET, COCOON, UNFOLDING, TC TOXIN, TOXIN
2z32:A (ILE328) to (VAL369) CRYSTAL STRUCTURE OF KEAP1 COMPLEXED WITH PROTHYMOSIN ALPHA | KELCH DOMAIN, B-PROPELLOR DOMAIN, NRF2 REGULATION, PROTHYMOSIN-A INTERACTOR, CYTOPLASM, KELCH REPEAT, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, UBL CONJUGATION, ACETYLATION, PHOSPHORYLATION, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2z3c:A (GLY109) to (TYR154) A MECHANISTIC VIEW OF ENZYME INHIBITION AND PEPTIDE HYDROLYSIS IN THE ACTIVE SITE OF THE SARS-COV 3C-LIKE PEPTIDASE | BETA BARRELS, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2z3d:A (GLY109) to (TYR154) A MECHANISTIC VIEW OF ENZYME INHIBITION AND PEPTIDE HYDROLYSIS IN THE ACTIVE SITE OF THE SARS-COV 3C-LIKE PEPTIDASE | BETA BARRELS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4a3i:H (LEU5) to (ALA60) RNA POLYMERASE II BINARY COMPLEX WITH DNA | TRANSCRIPTION, TRANSCRIPTION INITIATION
2z94:A (GLY109) to (TYR154) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH TDT | COMPLEX, HYDROLASE
1lto:A (GLN30) to (LEU68) HUMAN ALPHA1-TRYPTASE | HYDROLASE
1lto:D (GLN30) to (LEU68) HUMAN ALPHA1-TRYPTASE | HYDROLASE
2z9g:A (GLN110) to (TYR154) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH PMA | COMPLEX, ATP-BINDING, CYTOPLASM, ENDONUCLEASE, EXONUCLEASE, HELICASE, HYDROLASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RIBOSOMAL FRAMESHIFT, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
2z9j:A (GLN110) to (TYR154) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH EPDTC | COMPLEX, ATP-BINDING, CYTOPLASM, ENDONUCLEASE, EXONUCLEASE, HELICASE, HYDROLASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RIBOSOMAL FRAMESHIFT, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
2z9j:B (GLY109) to (TYR154) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH EPDTC | COMPLEX, ATP-BINDING, CYTOPLASM, ENDONUCLEASE, EXONUCLEASE, HELICASE, HYDROLASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RIBOSOMAL FRAMESHIFT, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
2za5:B (GLN30) to (LEU75) CRYSTAL STRUCTURE OF HUMAN TRYPTASE WITH POTENT NON-PEPTIDE INHIBITOR | TRYPTASE, SERINE PROTEASE, TETRAMER, HYDROLASE
2za5:D (GLN30) to (LEU75) CRYSTAL STRUCTURE OF HUMAN TRYPTASE WITH POTENT NON-PEPTIDE INHIBITOR | TRYPTASE, SERINE PROTEASE, TETRAMER, HYDROLASE
2zec:A (GLN30) to (LEU75) POTENT, NONPEPTIDE INHIBITORS OF HUMAN MAST CELL TRYPTASE | TRYPTASE, SERINE PROTEASE, HYDROLASE
2zec:D (GLN30) to (LEU75) POTENT, NONPEPTIDE INHIBITORS OF HUMAN MAST CELL TRYPTASE | TRYPTASE, SERINE PROTEASE, HYDROLASE
3kd4:A (PRO325) to (SER378) CRYSTAL STRUCTURE OF A PUTATIVE PROTEASE (BDI_1141) FROM PARABACTEROIDES DISTASONIS ATCC 8503 AT 2.00 A RESOLUTION | PUTATIVE PROTEASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, HYDROLASE
3kd4:B (PRO325) to (SER378) CRYSTAL STRUCTURE OF A PUTATIVE PROTEASE (BDI_1141) FROM PARABACTEROIDES DISTASONIS ATCC 8503 AT 2.00 A RESOLUTION | PUTATIVE PROTEASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, HYDROLASE
3kf2:A (GLU32) to (SER66) THE HCV NS3/NS4A PROTEASE APO STRUCTURE | HCV, NS3, PROTEASE, APO, HYDROLASE
1m7j:A (ASP428) to (ASN459) CRYSTAL STRUCTURE OF D-AMINOACYLASE DEFINES A NOVEL SUBSET OF AMIDOHYDROLASES | TIN-BARREL, METAL-DEPENDENT AMIDOHYDROLASE
1xx9:B (GLN30) to (GLY70) CRYSTAL STRUCTURE OF THE FXIA CATALYTIC DOMAIN IN COMPLEX WITH ECOTINM84R | FXIA; CATALYTIC DOMAIN; SERINE PROTEIN; ECOTIN, BLOOD CLOTTING- HYDROLASE INHIBITOR COMPLEX
1xxd:B (GLN30) to (SER69) CRYSTAL STRUCTURE OF THE FXIA CATALYTIC DOMAIN IN COMPLEX WITH MUTATED ECOTIN | FXIA; CATALYTIC DOMAIN; SERINE PROTEIN; ECOTIN, BLOOD CLOTTING/HYDROLASE INHIBITOR COMPLEX
1xyp:A (GLY106) to (ALA153) STRUCTURAL COMPARISON OF TWO MAJOR ENDO-1,4-BETA-XYLANASES FROM TRICHODREMA REESEI | XYLANASE, HYDROLASE
4ovu:A (ASP434) to (PHE486) CRYSTAL STRUCTURE OF P110ALPHA IN COMPLEX WITH NISH2 OF P85ALPHA | P110, P85, PI3KCA, PI3K, PIK3R1, PHOSPHATIDILYNOSITOL 3,4,5 TRIPHOSPHATE, PIP2, PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE, LIPID KINASE, PHOSPHOINOSITIDE, 3-KINASE, SIGNALING, PHOSPHATIDYLINOSITOL 3-KINASE
2zu5:A (GLY109) to (TYR154) COMPLEX STRUCTURE OF SARS-COV 3CL PROTEASE WITH TG-0205486 | PROTEASE-INHIBITOR COMPLEX, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1md8:A (TRP460) to (LEU504) MONOMERIC STRUCTURE OF THE ACTIVE CATALYTIC DOMAIN OF COMPLEMENT PROTEASE C1R | COMPLEMENT, INNATE IMMUNITY, SERINE PROTEASE, ACTIVATION, SUBSTRATE SPECIFICITY, HYDROLASE
2zuu:A (TYR112) to (ILE157) CRYSTAL STRUCTURE OF GALACTO-N-BIOSE/LACTO-N-BIOSE I PHOSPHORYLASE IN COMPLEX WITH GLCNAC | BETA-ALPHA-BARREL, TIM BARREL, GLYCOSYLTRANSFERASE, TRANSFERASE
2zw9:B (ASN502) to (PRO548) CRYSTAL STRUCTURE OF TRNA WYBUTOSINE SYNTHESIZING ENZYME TYW4 | TRANSFERASE
5d3d:B (GLY157) to (ASN197) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN 3 | SUPERANTIGENS, SUPERANTIGEN-LIKE PROTEINS, SSL, SSL3, TOLL-LIKE RECEPTOR 2, TLR2, IMMUNOLOGY, INFLAMMATION, INHIBITION, IMMUNE SYSTEM
4p22:B (PHE247) to (GLN294) CRYSTAL STRUCTURE OF N-TERMINAL FRAGMENTS OF E1 | E1, UBIQUITIN, LIGASE
3kn2:C (GLU32) to (SER66) HCV NS3 PROTEASE DOMAIN WITH KETOAMIDE INHIBITOR | HEPATITIS C VIRUS, NS3 PROTEASE DOMAIN, SERINE PROTEASE, KETOAMIDE INHIBITOR, ATP-BINDING, CAPSID PROTEIN, ENVELOPE PROTEIN, HELICASE, HOST MEMBRANE, HYDROLASE, MEMBRANE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, VIRION
4p71:A (VAL47) to (PRO90) APO PHERS FROM P. AEURIGINOSA | PHENYLALANINE TRNA SYNTHETASE, PHERS, LIGASE
4p71:B (VAL47) to (PRO90) APO PHERS FROM P. AEURIGINOSA | PHENYLALANINE TRNA SYNTHETASE, PHERS, LIGASE
4p73:A (VAL47) to (PRO90) PHERS IN COMPLEX WITH COMPOUND 1A | PHENYLALANYL-TRNA SYNTHETASE, PHERS, LIGASE-LIGASE INHIBITOR COMPLEX
4p73:B (VAL47) to (PRO90) PHERS IN COMPLEX WITH COMPOUND 1A | PHENYLALANYL-TRNA SYNTHETASE, PHERS, LIGASE-LIGASE INHIBITOR COMPLEX
4pb6:A (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:B (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:C (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:D (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:E (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:F (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:G (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:H (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:I (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:J (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:K (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:L (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:M (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:N (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:O (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:P (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:Q (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:R (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:S (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4pb6:T (ASP604) to (TYR647) FELINE CALICIVIRUS VP1 T=1 VIRUS-LIKE PARTICLE | VIRAL CAPSID PROTEIN, VIRUS-LIKE PARTICLE, VIRUS
4ajw:A (ASP430) to (PHE485) DISCOVERY AND OPTIMIZATION OF NEW BENZIMIDAZOLE- AND BENZOXAZOLE- PYRIMIDONE SELECTIVE PI3KBETA INHIBITORS FOR THE TREATMENT OF PHOSPHATASE AND TENSIN HOMOLOGUE (PTEN)-DEFICIENT CANCERS | TRANSFERASE, P110D
4ajw:B (ASP430) to (PHE485) DISCOVERY AND OPTIMIZATION OF NEW BENZIMIDAZOLE- AND BENZOXAZOLE- PYRIMIDONE SELECTIVE PI3KBETA INHIBITORS FOR THE TREATMENT OF PHOSPHATASE AND TENSIN HOMOLOGUE (PTEN)-DEFICIENT CANCERS | TRANSFERASE, P110D
4ak7:B (ALA314) to (SER354) CRYSTAL STRUCTURE OF BPGH117_E303Q IN COMPLEX WITH NEOAGAROBIOSE | HYDROLASE, MARINE GLYCOSIDE HYDROLASE, MARINE POLYSACCHARIDE DEGRADATION, MARINE CAZYMES, AGAR METABOLISM, SEAWEED BIOFUELS
1mws:B (THR423) to (LEU455) STRUCTURE OF NITROCEFIN ACYL-PENICILLIN BINDING PROTEIN 2A FROM METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS STRAIN 27R AT 2.00 A RESOLUTION. | PENICILLIN BINDING PROTEIN, BETA-LACTAM, D, D- TRANSPEPTIDASE, D-CARBOXYPEPTIDASE, NITROCEFIN, BIOSYNTHETIC PROTEIN
1mwt:A (THR423) to (LEU455) STRUCTURE OF PENICILLIN G ACYL-PENICILLIN BINDING PROTEIN 2A FROM METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS STRAIN 27R AT 2.45 A RESOLUTION. | PENICILLIN BINDING PROTEIN, BETA-LACTAM, D, D- TRANSPEPTIDASE, D-CARBOXYPEPTIDASE, PENICILLIN G, BIOSYNTHETIC PROTEIN
3kw3:B (LYS298) to (ILE339) CRYSTAL STRUCTURE OF ALANINE RACEMASE FROM BARTONELLA HENSELAE WITH COVALENTLY BOUND PYRIDOXAL PHOSPHATE | NIAID, SSGCID, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, IODIDE SOAK, ALANINE RACEMASE, LLP, CAT-SCRATCH DISEASE, ISOMERASE
1ylo:A (VAL97) to (PHE148) CRYSTAL STRUCTURE OF PROTEIN OF UNKNOWN FUNCTION (POSSIBLE AMINOPEPTIDASE) S2589 FROM SHIGELLA FLEXNERI 2A STR. 2457T | STRUCTURAL GENOMICS, MCSG, HYPOTHETICAL PROTEIN S2589, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, UNKNOWN FUNCTION
1n1l:B (GLU32) to (SER66) CRYSTAL STRUCTURE OF HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX WITH COVALENTLY BOUND INHIBITOR (GW472467X) | VIRAL PROTEIN, SERINE PROTEASE, NONSTRUCTURAL PROTEINS, COFACTOR PEPTIDE, HELICASE, INHIBITOR
3ade:A (ILE328) to (VAL369) CRYSTAL STRUCTURE OF KEAP1 IN COMPLEX WITH SEQUESTOSOME- 1/P62 | BETA-PROPELLER, KELCH MOTIF, TRANSCRIPTION
3l4t:A (ASN826) to (ALA869) CRYSTAL COMPLEX OF N-TERMINAL HUMAN MALTASE-GLUCOAMYLASE WITH BJ2661 | GLYCOSIDE HYDROLASE FAMILY 31, CELL MEMBRANE, DISULFIDE BOND, GLYCOPROTEIN, GLYCOSIDASE, HYDROLASE, MEMBRANE, MULTIFUNCTIONAL ENZYME, POLYMORPHISM, SIGNAL-ANCHOR, SULFATION, TRANSMEMBRANE
1z1j:B (GLN1110) to (TYR1154) CRYSTAL STRUCTURE OF SARS 3CLPRO C145A MUTANT | HYDROLASE
5dn6:B (GLU51) to (ARG90) ATP SYNTHASE FROM PARACOCCUS DENITRIFICANS | HYDROLASE, PARACOCCUS DENITRIFICANS, ATP SYNTHASE, COMPLEX, REGULATION, PROTON TRANSLOCATION
5dn6:F (ALA30) to (ASP72) ATP SYNTHASE FROM PARACOCCUS DENITRIFICANS | HYDROLASE, PARACOCCUS DENITRIFICANS, ATP SYNTHASE, COMPLEX, REGULATION, PROTON TRANSLOCATION
4pro:A (ILE7) to (ILE46) ALPHA-LYTIC PROTEASE COMPLEXED WITH PRO REGION | PRO REGION, FOLDASE, PROTEIN FOLDING, SERINE PROTEASE
4pro:B (ILE7) to (ILE46) ALPHA-LYTIC PROTEASE COMPLEXED WITH PRO REGION | PRO REGION, FOLDASE, PROTEIN FOLDING, SERINE PROTEASE
4prx:A (GLN128) to (PHE169) E. COLI GYRB 43-KDA N-TERMINAL FRAGMENT IN COMPLEX WITH ADP+PI | GYRB, ATP HYDROLYSIS, ISOMERASE
3lfi:B (TRP231) to (THR293) CRYSTAL STRUCTURE OF FRUCTOSYLTRANSFERASE (WILD-TYPE) FROM A. JAPONICUS IN COMPLEX WITH GLUCOSE | PROTEIN-OLIGOSACCHARIDE COMPLEX, FIVE BLADED BETA-PROPELLER FOLD, HYDROLASE
1z8g:A (GLN177) to (GLY220) CRYSTAL STRUCTURE OF THE EXTRACELLULAR REGION OF THE TRANSMEMBRANE SERINE PROTEASE HEPSIN WITH COVALENTLY BOUND PREFERRED SUBSTRATE. | SERINE PROTEASE HEPSIN, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5dq9:C (ILE89) to (VAL111) STRUCTURE OF S55-3 FAB IN COMPLEX WITH LIPID A | ANTIBODY, FAB, COMPLEX, CARBOHYDRATE, IMMUNE SYSTEM
5dqj:H (ILE89) to (VAL111) STRUCTURE OF UNLIGANDED S55-5 FAB | ANTIBODY, FAB, CARBOHYDRATE BINDING, PHOSPHOLIPID, IMMUNE SYSTEM
3lgw:A (GLN103) to (ASN160) H198P/T167V DOUBLE MUTANT OF DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lig:A (TRP231) to (THR293) CRYSTAL STRUCTURE OF FRUCTOSYLTRANSFERASE (D191A) FROM A. JAPONICUS | FIVE BLADED BETA-PROPELLER FOLD, HYDROLASE
5ds8:A (THR89) to (SER112) CONTEXT-INDEPENDENT ANTI-HYPUSINE ANTIBODY FABHPU98 IN COMPLEX WITH HYPUSINE | HYPUSINE, ANTIBODY, FABHPU98, EIF5A, IMMUNE SYSTEM
5ds8:H (THR89) to (SER112) CONTEXT-INDEPENDENT ANTI-HYPUSINE ANTIBODY FABHPU98 IN COMPLEX WITH HYPUSINE | HYPUSINE, ANTIBODY, FABHPU98, EIF5A, IMMUNE SYSTEM
3amm:B (GLU152) to (PHE196) CELLOTETRAOSE COMPLEX OF CELLULASE 12A FROM THERMOTOGA MARITIMA | BETA JELLYROLL, GLUCANASE, CELLULOSE, HYDROLASE
3amp:B (GLU152) to (PHE196) E134C-CELLOTETRAOSE COMPLEX OF CELLULASE 12A FROM THERMOTOGA MARITIMA | BETA JELLYROLL, GLUCANASE, CELLULOSE, HYDROLASE
1zgk:A (VAL324) to (VAL369) 1.35 ANGSTROM STRUCTURE OF THE KELCH DOMAIN OF KEAP1 | BETA-PROPELLER, KELCH REPEAT MOTIF, PROTEIN BINDING
5dub:A (THR89) to (SER112) CONTEXT-INDEPENDENT ANTI-HYPUSINE ANTIBODY FABHPU98 IN COMPLEX WITH DEOXYHYPUSINE | DEOXYHYPUSINE, ANTIBODY, FABHPU98, EIF5A, IMMUNE SYSTEM
5dub:H (THR89) to (SER112) CONTEXT-INDEPENDENT ANTI-HYPUSINE ANTIBODY FABHPU98 IN COMPLEX WITH DEOXYHYPUSINE | DEOXYHYPUSINE, ANTIBODY, FABHPU98, EIF5A, IMMUNE SYSTEM
3lky:A (SER20) to (GLY53) MONOMERIC GRIFFITHSIN WITH A SINGLE GLY-SER INSERTION | LECTIN, SUGAR-BINDING, ANTI-HIV, HIGH MANNOSE, MAN9, GP120, GP41, JACALIN-RELATED, MANNOSE-BINDING, SUGAR BINDING PROTEIN
1zjd:A (GLN30) to (GLY70) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH KUNITZ PROTEASE INHIBITOR DOMAIN OF PROTEASE NEXIN II | COAGULATION FACTOR XI; KUNITZ PROTEASE INHIBITORY DOMAIN; NEXIN II, HYDROLASE, BLOOD CLOTTING
1zjk:A (GLN459) to (MET499) CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC REGION OF HUMAN MASP-2 | BETA BARREL, MODULAR PROTEIN, HYDROLASE
5dxt:A (ASP434) to (PHE486) P110ALPHA WITH GDC-0326 | LIPID KINASE, TRANSFERASE-INHIBITOR COMPLEX
4q26:B (CYS42) to (VAL87) CRYSTAL STRUCTURE OF GALECTIN-1 IN COMPLEX WITH N-ACETYLLACTOSAMINE | SUGAR BINDING PROTEIN
4q26:H (CYS42) to (VAL87) CRYSTAL STRUCTURE OF GALECTIN-1 IN COMPLEX WITH N-ACETYLLACTOSAMINE | SUGAR BINDING PROTEIN
5dzp:A (ILE188) to (VAL226) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 2 WITH CARBAPENEM DRUG T206 IN CONFORMATION B | PEPTIDOGLYCAN SYNTHESIS ENZYME, CELL WALL ENZYME, TRANSFERASE
1znq:P (VAL171) to (LYS251) CRSYTAL STRUCTURE OF HUMAN LIVER GAPDH | ROSSMANN FOLD, OXIDOREDUCTASE
1znq:Q (VAL171) to (LYS251) CRSYTAL STRUCTURE OF HUMAN LIVER GAPDH | ROSSMANN FOLD, OXIDOREDUCTASE
3asq:B (CYS329) to (GLY382) CRYSTAL STRUCTURE OF P DOMAIN FROM NOROVIRUS FUNABASHI258 STAIN IN THE COMPLEX WITH H-ANTIGEN | PROTEIN-SUGAR COMPLEX, HISTO-BLOOD GROUP ANTIGEN, CAPSID PROTEIN, LECTIN-LIKE PROTEIN, VIRAL PROTEIN
3ast:B (CYS329) to (GLY382) CRYSTAL STRUCTURE OF P DOMAIN Q389N MUTANT FROM NOROVIRUS FUNABASHI258 STAIN IN THE COMPLEX WITH LEWIS-B | PROTEIN-SUGAR COMPLEX, HISTO-BLOOD GROUP ANTIGEN, CAPSID PROTEIN, LECTIN-LIKE PROTEIN, VIRAL PROTEIN
3atw:B (GLN110) to (TYR154) STRUCTURE-BASED DESIGN, SYNTHESIS, EVALUATION OF PEPTIDE-MIMETIC SARS 3CL PROTEASE INHIBITORS | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3aw1:B (GLN110) to (TYR154) STRUCTURE OF SARS 3CL PROTEASE AUTO-PROTEOLYSIS RESISTANT MUTANT IN THE ABSENT OF INHIBITOR | HYDROLASE PROTEINASE CONVERTING, HYDROLASE
2a5a:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF UNBOUND SARS CORONAVIRUS MAIN PEPTIDASE IN THE SPACE GROUP C2 | CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, LONG LOOP, ALPHA-HELICAL DOMAIN, DIMER, CATALYTIC DYAD, SPECIFICITY POCKETS, HYDROLASE
2a5i:A (GLY109) to (TYR154) CRYSTAL STRUCTURES OF SARS CORONAVIRUS MAIN PEPTIDASE INHIBITED BY AN AZA-PEPTIDE EPOXIDE IN THE SPACE GROUP C2 | CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, LONG LOOP, ALPHA-HELICAL DOMAIN, DIMER, CATALYTIC DYAD, SPECIFICITY POCKETS, AZA-PEPTIDE EPOXIDE, SUBSTRATE-LIKE INHIBITOR, C-S COVALENT BOND, EPOXIDE STEREOCHEMISTRY, HYDROLASE
2a5k:A (GLN110) to (TYR154) CRYSTAL STRUCTURES OF SARS CORONAVIRUS MAIN PEPTIDASE INHIBITED BY AN AZA-PEPTIDE EPOXIDE IN SPACE GROUP P212121 | CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, LONG LOOP, ALPHA-HELICAL DOMAIN, DIMER, CATALYTIC DYAD, SPECIFICITY POCKETS, AZA-PEPTIDE EPOXIDE, SUBSTRATE- LIKE INHIBITOR, C-S COVALENT BOND, EPOXIDE STEREOCHEMISTRY, HYDROLASE
2a5k:B (GLN110) to (ASN151) CRYSTAL STRUCTURES OF SARS CORONAVIRUS MAIN PEPTIDASE INHIBITED BY AN AZA-PEPTIDE EPOXIDE IN SPACE GROUP P212121 | CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, LONG LOOP, ALPHA-HELICAL DOMAIN, DIMER, CATALYTIC DYAD, SPECIFICITY POCKETS, AZA-PEPTIDE EPOXIDE, SUBSTRATE- LIKE INHIBITOR, C-S COVALENT BOND, EPOXIDE STEREOCHEMISTRY, HYDROLASE
3m3s:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE ASN214ALA MUTANT WITH AUTHORIZE N-TERMINUS | SARS CORONAVIRUS PROTEASE N214A MUTATION, HYDROLASE
3m3s:B (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE ASN214ALA MUTANT WITH AUTHORIZE N-TERMINUS | SARS CORONAVIRUS PROTEASE N214A MUTATION, HYDROLASE
3m3t:A (VAL18) to (ALA70) SARS-COV MAIN PROTEASE MONOMERIC ARG298ALA MUTANT WITH N-TERMINAL ADDITIONAL RESIDUES (GLY-SER) | SARS PROTEASE ARG298ALA MONOMERIC, HYDROLASE
3m7t:A (ILE7) to (ILE46) CRYSTAL STRUCTURE OF ALPHA-LYTIC PROTEASE SB2+3 E8A/R105S MUTANT | HYDROLASE, DISULFIDE BOND, PROTEASE, SERINE PROTEASE, ZYMOGEN
3m8l:C (ASP604) to (TYR647) CRYSTAL STRUCTURE ANALYSIS OF THE FELINE CALICIVIRUS CAPSID PROTEIN | FCV-5 CAPSID, ICOSAHEDRAL VIRUS, VIRUS
4b92:B (ASP401) to (ARG442) CRYSTAL STRUCTURE OF TRUNCATED HUMAN CRMP-5 SOAKED WITH ZN | SIGNALING PROTEIN, NEUROGENESIS, PHOSPHOPROTEIN, CRMP, TIM BARREL, AXONAL OUTGROWTH, DEVELOPMENTAL PROTEIN
3m9d:B (GLY159) to (ASP223) CRYSTAL STRUCTURE OF THE PROKARYOTIC UBIQUINTIN-LIKE PROTEIN PUP COMPLEXED WITH THE HEXAMERIC PROTEASOMAL ATPASE MPA WHICH INCLUDES THE AMINO TERMINAL COILED COIL DOMAIN AND THE INTER DOMAIN | ALPHA HELIX COIL COIL, 5 BETA-STRAND BARREL, ATP-BINDING, CHAPERONE, NUCLEOTIDE-BINDING, PROTEASOME, S-NITROSYLATION, VIRULENCE, ISOPEPTIDE BOND, UBL CONJUGATION PATHWAY
3m9d:D (GLY159) to (ASP223) CRYSTAL STRUCTURE OF THE PROKARYOTIC UBIQUINTIN-LIKE PROTEIN PUP COMPLEXED WITH THE HEXAMERIC PROTEASOMAL ATPASE MPA WHICH INCLUDES THE AMINO TERMINAL COILED COIL DOMAIN AND THE INTER DOMAIN | ALPHA HELIX COIL COIL, 5 BETA-STRAND BARREL, ATP-BINDING, CHAPERONE, NUCLEOTIDE-BINDING, PROTEASOME, S-NITROSYLATION, VIRULENCE, ISOPEPTIDE BOND, UBL CONJUGATION PATHWAY
3m9d:F (GLY159) to (ASP223) CRYSTAL STRUCTURE OF THE PROKARYOTIC UBIQUINTIN-LIKE PROTEIN PUP COMPLEXED WITH THE HEXAMERIC PROTEASOMAL ATPASE MPA WHICH INCLUDES THE AMINO TERMINAL COILED COIL DOMAIN AND THE INTER DOMAIN | ALPHA HELIX COIL COIL, 5 BETA-STRAND BARREL, ATP-BINDING, CHAPERONE, NUCLEOTIDE-BINDING, PROTEASOME, S-NITROSYLATION, VIRULENCE, ISOPEPTIDE BOND, UBL CONJUGATION PATHWAY
5ehd:D (GLN15) to (ALA64) CRYSTAL STRUCTURE OF HUMAN NUCLEOPHOSMIN-CORE IN COMPLEX WITH CYTOCHROME C | NUCLEOLUS, HISTONE ASSEMBLY, CITOCHROME C, APOPTOSIS, OXIDOREDUCTASE
3mfc:A (THR104) to (GLY154) COMPUTATIONALLY DESIGNED END0-1,4-BETA,XYLANASE | PEPTIDE BINDING, JELLY-ROLE, FAMILY 11, THUMB, GLYCOSIDASE, HYDROLASE, XYLAN DEGRADATION
3beu:B (PHE29) to (GLY68) NA+-DEPENDENT ALLOSTERY MEDIATES COAGULATION FACTOR PROTEASE ACTIVE SITE SELECTIVITY | BETA SHEETS, SERINE PROTEASE, HYDROLASE, ZYMOGEN
4bqf:A (PHE201) to (ASP231) ARABIDOPSIS THALIANA CYTOSOLIC ALPHA-1,4-GLUCAN PHOSPHORYLASE (PHS2) IN COMPLEX WITH ACARBOSE | TRANSFERASE, CARBOHYDRATE METABOLISM, SELF-ASSEMBLY ON SURFACES
4bqf:B (PHE201) to (ASP231) ARABIDOPSIS THALIANA CYTOSOLIC ALPHA-1,4-GLUCAN PHOSPHORYLASE (PHS2) IN COMPLEX WITH ACARBOSE | TRANSFERASE, CARBOHYDRATE METABOLISM, SELF-ASSEMBLY ON SURFACES
4bqi:A (PHE201) to (ASP231) ARABIDOPSIS THALIANA CYTOSOLIC ALPHA-1,4-GLUCAN PHOSPHORYLASE (PHS2) IN COMPLEX WITH MALTOTRIOSE | TRANSFERASE, CARBOHYDRATE METABOLISM, SELF-ASSEMBLY ON SURFACES
4bqi:B (PHE201) to (ASP231) ARABIDOPSIS THALIANA CYTOSOLIC ALPHA-1,4-GLUCAN PHOSPHORYLASE (PHS2) IN COMPLEX WITH MALTOTRIOSE | TRANSFERASE, CARBOHYDRATE METABOLISM, SELF-ASSEMBLY ON SURFACES
5f7s:A (ALA225) to (GLY271) CYCLOALTERNAN-DEGRADING ENZYME FROM TRUEPERELLA PYOGENES | HYDROLASE, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
4r4n:I (GLY412) to (SER447) CRYSTAL STRUCTURE OF THE ANTI-HIV-1 ANTIBODY 2.2C IN COMPLEX WITH HIV- 1 93UG037 GP120 | HIV-1 ATTACHMENT GLYCOPROTEIN, VIRAL PROTEIN-IMMUNE SYSTEM-INHIBITOR COMPLEX
5fgc:E (THR93) to (SER126) THREE DIMENSIONAL STRUCTURE OF BROADLY NEUTRALIZING HUMAN ANTI - HEPATITIS C VIRUS (HCV) GLYCOPROTEIN E2 FAB FRAGMENT HC33.8 | FAB FRAGMENT, NEUTRALIZING ANTIBODY, HEPATITIS C VIRUS E2, VIRAL PROTEIN
4r71:F (THR109) to (GLU151) STRUCTURE OF THE QBETA HOLOENZYME COMPLEX IN THE P1211 CRYSTAL FORM | OB FOLD, TRANSLATION, VIRAL PROTEIN-RIBOSOMAL PROTEIN COMPLEX
5fj8:H (LEU5) to (ILE59) CRYO-EM STRUCTURE OF YEAST RNA POLYMERASE III ELONGATION COMPLEX AT 3.9 A | RNA POLYMERASE III, POL III, TRANSCRIPTION, RNA POLYMERASE
5fj9:H (LEU5) to (ILE59) CRYO-EM STRUCTURE OF YEAST APO RNA POLYMERASE III AT 4.6 A | RNA POLYMERASE III, POL III, TRANSCRIPTION, RNA POLYMERASE
3cce:K (VAL74) to (VAL96) STRUCTURE OF ANISOMYCIN RESISTANT 50S RIBOSOMAL SUBUNIT: 23S RRNA MUTATION U2535A | 23S RRNA MUTATION U2535A, RIBOSOME
5fja:H (LEU5) to (ILE59) CRYO-EM STRUCTURE OF YEAST RNA POLYMERASE III AT 4.7 A | TRANSLATION, POL III, TRANSCRIPTION, RNA POLYMERASE,
3ccm:K (VAL74) to (VAL96) STRUCTURE OF ANISOMYCIN RESISTANT 50S RIBOSOMAL SUBUNIT: 23S RRNA MUTATION G2611U | G2611U MUTATION, 23S RRNA, LARGE RIBOSOMAL SUBUNIT, RIBOSOME
3ccu:K (VAL74) to (VAL96) STRUCTURE OF ANISOMYCIN RESISTANT 50S RIBOSOMAL SUBUNIT: 23S RRNA MUTATION G2482C | G2482C MUTATION, 23S RRNA, LARGE RIBOSOMAL SUBUNIT, RIBOSOME
3ccv:K (VAL74) to (VAL96) STRUCTURE OF ANISOMYCIN RESISTANT 50S RIBOSOMAL SUBUNIT: 23S RRNA MUTATION G2616A | G2616A MUTATION, 23S RRNA, LARGE RIBOSOMAL SUBUNIT, RIBOSOME
5fl7:E (ASN65) to (THR110) STRUCTURE OF THE F1C10 COMPLEX FROM YARROWIA LIPOLYTICA ATP SYNTHASE | HYDROLASE, ATP SYNTHASE FAMILY, NUCLEOTIDE BINDING, PROTON TRANSPORTING, ROTATIONAL MECHANISM, ATP BIOSYNTHETIC PROCESS, ATP SYNTHESIS/HYDROLYSIS
5fl7:F (ASN65) to (ASP109) STRUCTURE OF THE F1C10 COMPLEX FROM YARROWIA LIPOLYTICA ATP SYNTHASE | HYDROLASE, ATP SYNTHASE FAMILY, NUCLEOTIDE BINDING, PROTON TRANSPORTING, ROTATIONAL MECHANISM, ATP BIOSYNTHETIC PROCESS, ATP SYNTHESIS/HYDROLYSIS
3ne5:B (SER262) to (THR319) CRYSTAL STRUCTURE OF THE CUSBA HEAVY-METAL EFFLUX COMPLEX FROM ESCHERICHIA COLI | TRANSMEMBRANE HELIX, METAL TRANSPORT
3cia:A (ARG97) to (GLU144) CRYSTAL STRUCTURE OF COLD-AMINOPEPTIDASE FROM COLWELLIA PSYCHRERYTHRAEA | PSYCHROHILIC, HYDROLASE
3cia:C (ARG97) to (GLU144) CRYSTAL STRUCTURE OF COLD-AMINOPEPTIDASE FROM COLWELLIA PSYCHRERYTHRAEA | PSYCHROHILIC, HYDROLASE
4rh6:A (VAL56) to (ASN97) 2.9 ANGSTROM CRYSTAL STRUCTURE OF PUTATIVE EXOTOXIN 3 FROM STAPHYLOCOCCUS AUREUS. | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, SUPERANTIGEN-LIKE PROTEIN, EXOTOXIN 3, TOXIN
4rh6:B (THR57) to (ASN97) 2.9 ANGSTROM CRYSTAL STRUCTURE OF PUTATIVE EXOTOXIN 3 FROM STAPHYLOCOCCUS AUREUS. | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, SUPERANTIGEN-LIKE PROTEIN, EXOTOXIN 3, TOXIN
4rh6:C (THR57) to (ASN97) 2.9 ANGSTROM CRYSTAL STRUCTURE OF PUTATIVE EXOTOXIN 3 FROM STAPHYLOCOCCUS AUREUS. | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, SUPERANTIGEN-LIKE PROTEIN, EXOTOXIN 3, TOXIN
5fnt:A (ILE328) to (VAL369) STRUCTURE OF THE KEAP1 KELCH DOMAIN IN COMPLEX WITH A SMALL MOLECULE INHIBITOR. | TRANSCRIPTION, KEAP1, NRF2, OXIDATIVE STRESS
5fnu:A (ILE328) to (VAL369) STRUCTURE OF THE KEAP1 KELCH DOMAIN IN COMPLEX WITH A SMALL MOLECULE INHIBITOR. | TRANSCRIPTION, KEAP1, NRF2, OXIDATIVE STRESS
3nqi:A (GLY35) to (TYR74) CRYSTAL STRUCTURE OF A PUTATIVE LIPOPROTEIN (BF3042) FROM BACTEROIDES FRAGILIS NCTC 9343 AT 1.87 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LIPID BINDING PROTEIN
3nqi:B (GLY35) to (TYR72) CRYSTAL STRUCTURE OF A PUTATIVE LIPOPROTEIN (BF3042) FROM BACTEROIDES FRAGILIS NCTC 9343 AT 1.87 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LIPID BINDING PROTEIN
3nqi:C (GLY35) to (TYR72) CRYSTAL STRUCTURE OF A PUTATIVE LIPOPROTEIN (BF3042) FROM BACTEROIDES FRAGILIS NCTC 9343 AT 1.87 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LIPID BINDING PROTEIN
5ftl:A (ARG144) to (ALA177) CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION I) | HYDROLASE, SINGLE-PARTICLE, P97, AAA ATPASE
5ftl:B (ARG144) to (ALA177) CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION I) | HYDROLASE, SINGLE-PARTICLE, P97, AAA ATPASE
5ftl:C (ARG144) to (ALA177) CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION I) | HYDROLASE, SINGLE-PARTICLE, P97, AAA ATPASE
5ftl:D (ARG144) to (ALA177) CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION I) | HYDROLASE, SINGLE-PARTICLE, P97, AAA ATPASE
5ftl:E (ARG144) to (ALA177) CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION I) | HYDROLASE, SINGLE-PARTICLE, P97, AAA ATPASE
5ftl:F (ARG144) to (ALA177) CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION I) | HYDROLASE, SINGLE-PARTICLE, P97, AAA ATPASE
5ftm:A (ARG144) to (PRO178) CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION II) | HYDROLASE, SINGLE-PARTICLE, P97, AAA ATPASE
5ftm:B (ARG144) to (PRO178) CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION II) | HYDROLASE, SINGLE-PARTICLE, P97, AAA ATPASE
5ftm:C (ARG144) to (PRO178) CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION II) | HYDROLASE, SINGLE-PARTICLE, P97, AAA ATPASE
5ftm:D (ARG144) to (PRO178) CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION II) | HYDROLASE, SINGLE-PARTICLE, P97, AAA ATPASE
5ftm:E (ARG144) to (PRO178) CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION II) | HYDROLASE, SINGLE-PARTICLE, P97, AAA ATPASE
5ftm:F (ARG144) to (PRO178) CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION II) | HYDROLASE, SINGLE-PARTICLE, P97, AAA ATPASE
3csv:A (ASP181) to (LEU216) CRYSTAL STRUCTURE OF A PUTATIVE AMINOGLYCOSIDE PHOSPHOTRANSFERASE (YP_614837.1) FROM SILICIBACTER SP. TM1040 AT 2.15 A RESOLUTION | YP_614837.1, PUTATIVE AMINOGLYCOSIDE PHOSPHOTRANSFERASE, PHOSPHOTRANSFERASE ENZYME FAMILY, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, TRANSFERASE
5fzj:A (ILE328) to (VAL369) STRUCTURE OF THE KEAP1 KELCH DOMAIN IN COMPLEX WITH A SMALL MOLECULE INHIBITOR. | TRANSCRIPTION, KEAP1, NRF2, OXIDATIVE STRESS
4crn:P (CYS600) to (ARG668) CRYO-EM OF A PRETERMINATION COMPLEX WITH ERF1 AND ERF3 | TRANSLATION, TERMINATION, CRYO-EM
4sgb:E (ASP31) to (ALA66) STRUCTURE OF THE COMPLEX OF STREPTOMYCES GRISEUS PROTEINASE B AND POLYPEPTIDE CHYMOTRYPSIN INHIBITOR-1 FROM RUSSET BURBANK POTATO TUBERS AT 2.1 ANGSTROMS RESOLUTION | COMPLEX(SERINE PROTEINASE-INHIBITOR)
5g4f:E (ARG126) to (GLU166) STRUCTURE OF THE ADP-BOUND VAT COMPLEX | HYDROLASE, VAT, PROTEASOME, PROTEIN DYNAMICS, UNFOLDASE, CONFORMATIONS, AAA ATPASE
3d62:A (GLY109) to (TYR154) DEVELOPMENT OF BROAD-SPECTRUM HALOMETHYL KETONE INHIBITORS AGAINST CORONAVIRUS MAIN PROTEASE 3CLPRO | MAIN PROTEASE 3CLPRO, SARS, INHIBITOR, 95990, ATP-BINDING, ENDONUCLEASE, EXONUCLEASE, HELICASE, HYDROLASE, MEMBRANE, METAL- BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC-FINGER
3oe7:D (ASN35) to (GLY80) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: GAMMA-I270T | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, ADP, PO4, MITOCHONDRIA, HYDROLASE
3oe7:M (ASN35) to (GLY80) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: GAMMA-I270T | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, ADP, PO4, MITOCHONDRIA, HYDROLASE
3oe7:O (ASN35) to (GLY80) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: GAMMA-I270T | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, ADP, PO4, MITOCHONDRIA, HYDROLASE
3oe7:X (ASN35) to (THR79) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: GAMMA-I270T | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, ADP, PO4, MITOCHONDRIA, HYDROLASE
3oee:O (ASN35) to (ASP78) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: ALPHA-F405S | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, HYDROLASE, ADP, PO4, MITOCHONDRIA
3oee:S (GLU53) to (GLY94) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: ALPHA-F405S | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, HYDROLASE, ADP, PO4, MITOCHONDRIA
3oee:V (ASN35) to (ASP78) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: ALPHA-F405S | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, HYDROLASE, ADP, PO4, MITOCHONDRIA
3oeh:O (ASN35) to (GLY80) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: BETA-V279F | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, HYDROLASE, ADP, PO4, MITOCHONDRIA
3oeh:W (ASN35) to (GLY80) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: BETA-V279F | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, HYDROLASE, ADP, PO4, MITOCHONDRIA
3ofn:D (ASN35) to (ASP78) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: ALPHA-N67I | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, HYDROLASE, ADP, PO4, MITOCHONDRIA
3ofn:V (ASN35) to (ASP78) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: ALPHA-N67I | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, HYDROLASE, ADP, PO4, MITOCHONDRIA
5gjm:A (PRO304) to (THR347) CRYSTAL STRCUTURE OF LYSINE DECARBOXYLASE FROM SELENOMONAS RUMINANTIUM IN C2 SPACE GROUP | BARREL DOMAIN, LYASE
5gjp:A (TYR303) to (THR347) CRYSTAL STRCUTURE OF SRLDC IN COMPLEX WITH PLP AND CADAVERINE | BARREL DOMAIN, LYASE
4tt3:E (ALA35) to (ASP77) THE PATHWAY OF BINDING OF THE INTRINSICALLY DISORDERED MITOCHONDRIAL INHIBITOR PROTEIN TO F1-ATPASE | HYDROLASE, INHIBITOR PROTEIN
4tuu:A (ASP434) to (PHE486) ISOLATED P110A SUBUNIT OF PI3KA PROVIDES A PLATFORM FOR STRUCTURE- BASED DRUG DESIGN | LIPID KINASE ACTIVITY, ATPASE ACTIVITY, SURFACE PLASMON RESONANCE (SPR), ISOTHERMAL TITRATION CALORIMETRY (ITC)., TRANSFERASE
4twy:A (GLY109) to (TYR154) STRUCTURE OF SARS-3CL PROTEASE COMPLEX WITH A PHENYLBENZOYL (S,R)-N- DECALIN TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDRASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5gtq:A (GLY69) to (LEU109) LUCIFERIN-REGENERATING ENZYME AT CRYOGENIC TEMPERATURE | BETA-PROOELLER, HYDROLASE
4d5o:A (GLY205) to (GLY240) HYPOCREA JECORINA CELLOBIOHYDROLASE CEL7A E212Q SOAKED WITH XYLOPENTAOSE. | HYDROLASE, GLYCOSIDE HYDROLASE, CELLOBIOHYDROLASE, CELLULASE. INHIBITION, XYLOOLIGOSACCHARIDES
3ony:B (ASN263) to (GLY288) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH FUCOSE | CAPSID PROTEIN, VIRAL PROTEIN
3ony:C (ASN263) to (GLY288) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH FUCOSE | CAPSID PROTEIN, VIRAL PROTEIN
3opo:A (GLN263) to (GLU322) CRYSTAL STRUCTURE OF THE MEMBRANE FUSION PROTEIN CUSB FROM ESCHERICHIA COLI | BETA BARREL, COPPER TRANSPORT, ION TRANSPORT, TRANSPORT, TRANSPORT PROTEIN, CUSA,CUSC
3ow7:A (GLN263) to (GLU322) CRYSTAL STRUCTURE OF THE MEMBRANE FUSION PROTEIN CUSB FROM ESCHERICHIA COLI. | THREE-HELIX BUNDLE, BETA BARREL, COPPER TRANSPORT, ION TRANSPORT, TRANSPORT, TRANSPORT PROTEIN
4dg6:A (THR309) to (ALA345) CRYSTAL STRUCTURE OF DOMAINS 1 AND 2 OF LRP6 | 6-BLADED BETA PROPELLER, SCLEROSTIN RECEPTOR, EGF, WNT, MESD, SIGNALING PROTEIN
3p16:A (MET163) to (PRO207) CRYSTAL STRUCTURE OF DNA POLYMERASE III SLIDING CLAMP | DNA POLYMERASE III SLIDING CLAMP, TRANSFERASE
5hkk:B (GLU51) to (ARG90) CALDALAKLIBACILLUS THERMARUM F1-ATPASE (WILD TYPE) | HYDROLASE, F1-ATPASE, COMPLEX
5hkk:C (GLU51) to (ARG90) CALDALAKLIBACILLUS THERMARUM F1-ATPASE (WILD TYPE) | HYDROLASE, F1-ATPASE, COMPLEX
5hkk:J (GLU51) to (ARG90) CALDALAKLIBACILLUS THERMARUM F1-ATPASE (WILD TYPE) | HYDROLASE, F1-ATPASE, COMPLEX
5hkk:K (GLU51) to (ARG90) CALDALAKLIBACILLUS THERMARUM F1-ATPASE (WILD TYPE) | HYDROLASE, F1-ATPASE, COMPLEX
3e1t:A (PRO74) to (GLU109) STRUCTURE AND ACTION OF THE MYXOBACTERIAL CHONDROCHLOREN HALOGENASE CNDH, A NEW VARIANT OF FAD-DEPENDENT HALOGENASES | FAD DEPENDENT HALOGENASE, FLAVOPROTEIN
4udi:D (GLY53) to (CYS108) CRYSTAL STRUCTURE OF B-1,4-MANNOPYRANOSYL-CHITOBIOSE PHOSPHORYLASE AT 1.85 ANGSTROM FROM UNKNOWN HUMAN GUT BACTERIA (UHGB_MP) | TRANSFERASE, GLYCOSIDE HYDROLASE FAMILY 130, B-1, 4-MANNOPYRANOSYL- CHITOBIOSE PHOSPHORYLASE, N-GLYCAN PHOSPHOROLYSIS
5hyo:B (PHE111) to (ASN153) X-RAY STRUCTURE OF UNBOUND PORCINE EPIDEMIC DIARRHEA VIRUS 3CLPRO | PEDV, 3CLPRO, CORONAVIRUS, MPRO, VIRAL PROTEIN
5hyt:B (PRO4) to (HIS41) STRUCTURE OF HUMAN C4B-BINIDNG PROTEIN ALPHA CHAIN CCP DOMAINS 1 AND 2 IN COMPLEX WITH THE HYPERVARIABLE REGION OF GROUP A STREPTOCOCCUS M22 PROTEIN | M PROTEIN, COMPLEMENT, STREPTOCOCCUS PYOGENES, HYPERVARIABLE ANTIGEN, IMMUNE SYSTEM
3pro:A (ILE7) to (ILE46) ALPHA-LYTIC PROTEASE COMPLEXED WITH C-TERMINAL TRUNCATED PRO REGION | PRO REGION, FOLDASE, PROTEIN FOLDING, SERINE PROTEASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3pro:B (ILE7) to (ILE46) ALPHA-LYTIC PROTEASE COMPLEXED WITH C-TERMINAL TRUNCATED PRO REGION | PRO REGION, FOLDASE, PROTEIN FOLDING, SERINE PROTEASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4e9w:A (ALA1002) to (GLN1040) MULTICOPPER OXIDASE MGLAC (DATA2) | MULTICOPPER OXIDASE, METAL BINDING PROTEIN
4e9y:A (ALA1002) to (GLN1040) MULTICOPPER OXIDASE MGLAC (DATA4) | MULTICOPPER OXIDASE, METAL BINDING PROTEIN
4ecl:A (LEU253) to (PRO281) CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF VANCOMYCIN RESISTANCE SERINE RACEMASE VANTG | ANTIBIOTIC RESISTANCE, VANCOMYCIN RESISTANCE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES (CSGID), ALPHA/BETA BARREL, TIM BARREL, TYPE III PYRIDOXAL 5-PHOSPHATE (PLP)-DEPENDENT ENZYME, ACYLTRANSFERASE FAMILY, L-SERINE RACEMASE, D-SERINE RACEMASE, ISOMERASE, L-SERINE, D-SERINE, PLP, PYRIDOXAL 5-PHOSPHATE, CYTOPLASMIC
4ecl:A (ASN296) to (LEU335) CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF VANCOMYCIN RESISTANCE SERINE RACEMASE VANTG | ANTIBIOTIC RESISTANCE, VANCOMYCIN RESISTANCE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES (CSGID), ALPHA/BETA BARREL, TIM BARREL, TYPE III PYRIDOXAL 5-PHOSPHATE (PLP)-DEPENDENT ENZYME, ACYLTRANSFERASE FAMILY, L-SERINE RACEMASE, D-SERINE RACEMASE, ISOMERASE, L-SERINE, D-SERINE, PLP, PYRIDOXAL 5-PHOSPHATE, CYTOPLASMIC
4ecl:C (LEU253) to (PRO281) CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF VANCOMYCIN RESISTANCE SERINE RACEMASE VANTG | ANTIBIOTIC RESISTANCE, VANCOMYCIN RESISTANCE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES (CSGID), ALPHA/BETA BARREL, TIM BARREL, TYPE III PYRIDOXAL 5-PHOSPHATE (PLP)-DEPENDENT ENZYME, ACYLTRANSFERASE FAMILY, L-SERINE RACEMASE, D-SERINE RACEMASE, ISOMERASE, L-SERINE, D-SERINE, PLP, PYRIDOXAL 5-PHOSPHATE, CYTOPLASMIC
4ecl:D (LEU253) to (PRO281) CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF VANCOMYCIN RESISTANCE SERINE RACEMASE VANTG | ANTIBIOTIC RESISTANCE, VANCOMYCIN RESISTANCE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES (CSGID), ALPHA/BETA BARREL, TIM BARREL, TYPE III PYRIDOXAL 5-PHOSPHATE (PLP)-DEPENDENT ENZYME, ACYLTRANSFERASE FAMILY, L-SERINE RACEMASE, D-SERINE RACEMASE, ISOMERASE, L-SERINE, D-SERINE, PLP, PYRIDOXAL 5-PHOSPHATE, CYTOPLASMIC
4ecl:D (ASN296) to (ILE336) CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF VANCOMYCIN RESISTANCE SERINE RACEMASE VANTG | ANTIBIOTIC RESISTANCE, VANCOMYCIN RESISTANCE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES (CSGID), ALPHA/BETA BARREL, TIM BARREL, TYPE III PYRIDOXAL 5-PHOSPHATE (PLP)-DEPENDENT ENZYME, ACYLTRANSFERASE FAMILY, L-SERINE RACEMASE, D-SERINE RACEMASE, ISOMERASE, L-SERINE, D-SERINE, PLP, PYRIDOXAL 5-PHOSPHATE, CYTOPLASMIC
3pv2:B (PHE141) to (ASN199) STRUCTURE OF LEGIONELLA FALLONII DEGQ (WT) | TRYPSIN FOLD, PDZ DOMAIN, CHAPERONE PROTEASE, HYDROLASE
3pv4:A (PHE141) to (ASN199) STRUCTURE OF LEGIONELLA FALLONII DEGQ (DELTA-PDZ2 VARIANT) | TRYPSIN FOLD, PDZ DOMAIN, CHAPERONE PROTEASE, HYDROLASE
5ik2:B (GLU51) to (ARG90) CALDALAKLIBACILLUS THERMARUM F1-ATPASE (EPSILON MUTANT) | HYDROLASE, F1-ATPASE, COMPLEX
5ik2:J (GLU51) to (ARG90) CALDALAKLIBACILLUS THERMARUM F1-ATPASE (EPSILON MUTANT) | HYDROLASE, F1-ATPASE, COMPLEX
4em7:A (SER132) to (PHE176) CRYSTAL STRUCTURE OF A TOPOISOMERASE ATP INHIBITOR | PROTEIN-INHIBITOR COMPLEX, ATP BINDING, STRUCTURE-BASED DRUG DESIGN, ANTIMICROBIAL, VIRTUAL SCREEN, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
4emv:A (SER132) to (PHE176) CRYSTAL STRUCTURE OF A TOPOISOMERASE ATP INHIBITOR | PROTEIN-INHIBITOR COMPLEX, ATP BINDING, STRUCTURE-BASED DRUG DESIGN, ANTIMICROBIAL, VIRTUAL SCREEN, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
4eps:A (ASP68) to (TYR116) CRYSTAL STRUCTURE OF A FIMBRIAL PROTEIN (BACOVA_04982) FROM BACTEROIDES OVATUS ATCC 8483 AT 1.85 A RESOLUTION | HYPOTHETICAL PROTEIN (DUF3988), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
3q4j:A (LEU33) to (PRO71) STRUCTURE OF A SMALL PEPTIDE LIGAND BOUND TO E.COLI DNA SLIDING CLAMP | DNA POLYMERASE, SLIDING CLAMP, PROCESSIVITY FACTORS, LIGAND BINDING, DNA REPLICATION, DNA-DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-PEPTIDE COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3q4j:D (LEU33) to (PRO71) STRUCTURE OF A SMALL PEPTIDE LIGAND BOUND TO E.COLI DNA SLIDING CLAMP | DNA POLYMERASE, SLIDING CLAMP, PROCESSIVITY FACTORS, LIGAND BINDING, DNA REPLICATION, DNA-DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, TRANSFERASE-PEPTIDE COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5itd:A (ASP434) to (PHE486) CRYSTAL STRUCTURE OF PI3K ALPHA WITH PI3K DELTA INHIBITOR | INHIBITOR, LIPID KINASE, PI3K, ALPHA, DELTA, TRANSFERASE-PROTEIN TRANSPORT-INHIBITOR COMPLEX
5iy6:H (GLU89) to (LYS147) HUMAN HOLO-PIC IN THE CLOSED STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
5iy9:H (LEU5) to (ALA61) HUMAN HOLO-PIC IN THE INITIAL TRANSCRIBING STATE (NO IIS) | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA- RNA COMPLEX
5iyd:H (LEU5) to (ALA61) HUMAN CORE-PIC IN THE INITIAL TRANSCRIBING STATE (NO IIS) | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA- RNA COMPLEX
4fa1:F (LYS149) to (THR187) CRYSTAL STRUCTURE OF WT MAUG IN COMPLEX WITH PRE-METHYLAMINE DEHYDROGENASE AGED 130 DAYS. | TRYPTOPHAN TRYPTOPHYLQUINONE, OXIDOREDUCTASE-ELECTRON TRANSFER COMPLEX, OXIDOREDUCTASE-ELECTRON TRANSPORT COMPLEX
4fa9:F (LYS149) to (THR187) CRYSTAL STRUCTURE OF WT MAUG IN COMPLEX WITH PRE-METHYLAMINE DEHYDROGENASE AGED 30 DAYS | TRYPTOPHAN TRYPTOPHYLQUINON, OXIDOREDUCTASE-ELECTRON TRANSFER COMPLEX, OXIDOREDUCTASE-ELECTRON TRANSPORT COMPLEX
4fan:F (LYS149) to (THR187) CRYSTAL STRUCTURE OF WT MAUG IN COMPLEX WITH PRE-METHYLAMINE DEHYDROGENASE AGED 40 DAYS | OXIDOREDUCTASE/ELECTRON TRANSFER, TRYPTOPHAN TRYPTOPHYLQUINONE, OXIDOREDUCTASE-ELECTRON TRANSFER COMPLEX, OXIDOREDUCTASE-ELECTRON TRANSPORT COMPLEX
4fav:F (LYS149) to (THR187) CRYSTAL STRUCTURE OF WT MAUG IN COMPLEX WITH PRE-METHYLAMINE DEHYDROGENASE AGED 50 DAYS | TRYPTOPHAN TRYPTOPHYLQUINONE, OXIDOREDUCTASE-ELECTRON TRANSFER COMPLEX, OXIDOREDUCTASE-ELECTRON TRANSPORT COMPLEX
4fe9:A (GLY167) to (PRO211) CRYSTAL STRUCTURE OF SUSF FROM BACTEROIDES THETAIOTAOMICRON | STARCH BINDING, IG FOLD, EXTRACELLULAR SURFACE, OUTERMEMBRANE, CARBOHYDRATE-BINDING PROTEIN
4fe9:A (PRO383) to (LYS434) CRYSTAL STRUCTURE OF SUSF FROM BACTEROIDES THETAIOTAOMICRON | STARCH BINDING, IG FOLD, EXTRACELLULAR SURFACE, OUTERMEMBRANE, CARBOHYDRATE-BINDING PROTEIN
4fem:A (ALA283) to (PHE329) STRUCTURE OF SUSE WITH ALPHA-CYCLODEXTRIN | STARCH BINDING, EXTRACELLULAR, OUTERMEMBRANE, CARBOHYDRATE-BINDING PROTEIN
3qsy:A (LEU357) to (ALA402) RECOGNITION OF THE METHIONYLATED INITIATOR TRNA BY THE TRANSLATION INITIATION FACTOR 2 IN ARCHAEA | TRANSLATION INITIATION, ARCHAEA, E/AIF2, TRNAI, G-PROTEIN, GTP BINDING, MET-TRNAI BINDING, RIBOSOME BINDING, MRNA BINDING, RIBOSOME, TRANSLATION-RNA COMPLEX
3qva:A (THR21) to (ALA59) STRUCTURE OF KLEBSIELLA PNEUMONIAE 5-HYDROXYISOURATE HYDROLASE | TRANSTHYRETIN-RELATED PROTEIN, 5-HYDROXYISOURATE HYDROLASE, HYDROLASE
3qva:B (THR21) to (ALA59) STRUCTURE OF KLEBSIELLA PNEUMONIAE 5-HYDROXYISOURATE HYDROLASE | TRANSTHYRETIN-RELATED PROTEIN, 5-HYDROXYISOURATE HYDROLASE, HYDROLASE
3qva:D (THR21) to (ALA59) STRUCTURE OF KLEBSIELLA PNEUMONIAE 5-HYDROXYISOURATE HYDROLASE | TRANSTHYRETIN-RELATED PROTEIN, 5-HYDROXYISOURATE HYDROLASE, HYDROLASE
4w8j:A (ASN301) to (GLN353) STRUCTURE OF THE FULL-LENGTH INSECTICIDAL PROTEIN CRY1AC REVEALS INTRIGUING DETAILS OF TOXIN PACKAGING INTO IN VIVO FORMED CRYSTALS | TOXIN, INSECTICIDAL, PORE FORMING, PROTOXIN
4fs9:A (ALA280) to (THR317) COMPLEX STRUCTURE OF A BROAD SPECIFICITY AMINO ACID RACEMASE (BAR) WITHIN THE REACTIVE INTERMEDIATE | ISOMERASE, PLP BINDING, RACEMIZATION
5knb:F (LEU29) to (PHE72) CRYSTAL STRUCTURE OF THE 2 ADP-BOUND V1 COMPLEX | P-LOOP, HYDROLASE, NA(+)-ATPASE, ATP BINDING
5knc:F (LEU29) to (PHE72) CRYSTAL STRUCTURE OF THE 3 ADP-BOUND V1 COMPLEX | P-LOOP, HYDROLASE, NA(+)-ATPASE, ATP BINDING
4gpv:A (ASN67) to (ALA109) CRYSTAL STRUCTURE OF A PUTATIVE CELL ADHESION PROTEIN (BACEGG_00536) FROM BACTEROIDES EGGERTHII DSM 20697 AT 1.67 A RESOLUTION | MAJOR FIMBRIAL SUBUNIT PROTEIN (FIMA), PF06321 FAMILY, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, CELL ADHESION
4gpv:B (ASN67) to (ALA109) CRYSTAL STRUCTURE OF A PUTATIVE CELL ADHESION PROTEIN (BACEGG_00536) FROM BACTEROIDES EGGERTHII DSM 20697 AT 1.67 A RESOLUTION | MAJOR FIMBRIAL SUBUNIT PROTEIN (FIMA), PF06321 FAMILY, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, CELL ADHESION
5l46:B (GLU788) to (GLU832) CRYSTAL STRUCTURE OF HUMAN DIMETHYLGLYCINE-DEHYDROGENASE | ELECTRON TRANSFER, COVALENT FLAVINYLATION, OXIDOREDUCTASE, ONE-CARBON METABOLISM
5lpr:A (ILE29) to (ILE80) STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ea7:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE TRIPLE MUTANT STI/A IN SPACE GROUP P21 | SARS-COV MAIN PROTEASE MUTANT, 3C-LIKE PROTEASE MUTANT, EXTRA HELICAL DOMAIN MUTATION, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC- FINGER
2amq:A (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N3 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
1bf8:A (THR153) to (ASP192) PERIPLASMIC CHAPERONE FIMC, NMR, 20 STRUCTURES | CHAPERONE, FIMC, PERIPLASMIC CHAPERONE, PILUS CHAPERONE, TYPE-I PILI
3eyv:B (GLY92) to (SER118) ANTI-LEWIS Y FAB FRAGMENT WITH LEWIS Y ANTIGEN IN THE PRESENCE OF ZINC IONS | IMMUNOGLOBULIN FOLD, BETA BARREL, HUMANIZED ANTIBODY, ANTIGEN BINDING FRAGMENT, IMMUNE SYSTEM
4x6a:H (ILE9) to (ALA60) CRYSTAL STRUCTURE OF YEAST RNA POLYMERASE II ENCOUNTERING OXIDATIVE CYCLOPURINE DNA LESIONS | POL II ELONGATION COMPLEX OXIDATIVE CYCLOPURINE DNA LESIONS, TRANSCRIPTION-DNA COMPLEX
3fbq:A (ASP193) to (THR243) THE CRYSTAL STRUCTURE OF THE CONSERVED DOMAIN PROTEIN FROM BACILLUS ANTHRACIS | CONSERVED DOMAIN PROTEIN, BACILLUS ANTHRACIS, STRUCTURAL GENOMICS, PSI2, MCSG, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, UNKNOWN FUNCTION
2bx4:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (P21212) | HYDROLASE, ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A- HELICES, VIRAL PROTEIN
1ohh:F (ALA35) to (ASP77) BOVINE MITOCHONDRIAL F1-ATPASE COMPLEXED WITH THE INHIBITOR PROTEIN IF1 | SYNTHASE, ATP PHOSPHORYLASE, ATP PHOSPHORYLASE (H+ TRANSPORTING), ATP SYNTHASE, F1FO ATP SYNTHASE, F1-ATPASE
3snd:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AC- ESTLQ-H (COCRYSTALLIZATION) | 3C-LIKE PROTEINASE, PROTEASE, AC-ESTLQ-H, ACTIVE SITE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3snd:B (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AC- ESTLQ-H (COCRYSTALLIZATION) | 3C-LIKE PROTEINASE, PROTEASE, AC-ESTLQ-H, ACTIVE SITE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
1cso:E (ASP29) to (ALA68) CRYSTAL STRUCTURE OF THE OMTKY3 P1 VARIANT OMTKY3-ILE18I IN COMPLEX WITH SGPB | ENZYME-INHIBITOR COMPLEX, BETA-BRANCHED P1 RESIDUE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1p01:A (ILE29) to (ILE80) SERINE PROTEASE MECHANISM. STRUCTURE OF AN INHIBITORY COMPLEX OF ALPHA-LYTIC PROTEASE AND A TIGHTLY BOUND PEPTIDE BORONIC ACID | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1p02:A (ILE29) to (ILE80) STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3fzd:A (GLN110) to (TYR154) MUTATION OF ASN28 DISRUPTS THE ENZYMATIC ACTIVITY AND DIMERIZATION OF SARS 3CLPRO | SARS, SARS 3CLPRO, PROTEASE, SARS-COV MPRO, DIMERIZATION, ANALYTICAL ULTRACENTRIFUGATION, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
4in3:A (SER2) to (LEU53) CRYSTAL STRUCTURE OF THE CHS5-BCH1 EXOMER CARGO ADAPTOR COMPLEX | OB FOLD, TPR DOMAIN, TRANS-GOLGI NETWORK, TGN, PROTEIN TRANSPORT
4iqk:A (ILE328) to (VAL369) CRYSTAL STRUCTURE OF CPD 16 BOUND TO KEAP1 KELCH DOMAIN | TRANSCRIPTION
1ds2:E (ASP29) to (ALA68) CRYSTAL STRUCTURE OF SGPB:OMTKY3-COO-LEU18I | SERINE PROTEINASE, PROTEIN INHIBITOR, OVOMUCOID, CANONICAL INHIBITOR, ESTER BOND, SGPB, OMTKY3, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2dbv:Q (VAL168) to (ALA244) GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE MUTANT WITH ASP 32 REPLACED BY GLY, LEU 187 REPLACED BY ALA, AND PRO 188 REPLACED BY SER COMPLEXED WITH NADP+ | OXIDOREDUCTASE, NAD(P) SELECTIVITY
4j3v:A (CYS30) to (SER61) CRYSTAL STRUCTURE OF BARLEY LIMIT DEXTRINASE IN COMPLEX WITH A BRANCHED THIO-LINKED HEXASACCHARIDE | GH13 HYDROLASE, HYDROLASE
2r5j:G (PHE247) to (GLN312) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 35 | HPV35, CAPSID, PENTAMER, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID PROTEIN, LATE PROTEIN, VIRION, VIRAL PROTEIN
2r5j:I (PHE247) to (LEU311) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 35 | HPV35, CAPSID, PENTAMER, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID PROTEIN, LATE PROTEIN, VIRION, VIRAL PROTEIN
3tja:B (SER19) to (GLU66) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI UREE IN THE APO FORM | METAL BINDING PROTEIN
2duc:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE(3CLPRO) | HYDROLASE, SARS CORONAVIRUS MAIN PROTEINASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2duc:B (GLN110) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE(3CLPRO) | HYDROLASE, SARS CORONAVIRUS MAIN PROTEINASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2rfw:C (PRO205) to (THR240) CRYSTAL STRUCTURE OF CELLOBIOHYDROLASE FROM MELANOCARPUS ALBOMYCES | HYDROLASE, GLYCOSIDASE
1qh7:A (GLY113) to (SER160) CATALYSIS AND SPECIFICITY IN ENZYMATIC GLYCOSIDE HYDROLASES: A 2,5B CONFORMATION FOR THE GLYCOSYL-ENZYME INTERMIDIATE REVEALED BY THE STRUCTURE OF THE BACILLUS AGARADHAERENS FAMILY 11 XYLANASE | GLYCOSYL HYDROLASE
2e28:A (ALA120) to (ASN155) CRYSTAL STRUCTURE ANALYSIS OF PYRUVATE KINASE FROM BACILLUS STEAROTHERMOPHILUS | PYRUVATE KINASE, ALLOSTERIC, TRANSFERASE
2sgp:E (ASP29) to (ALA68) PRO 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5 | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/INHIBITOR COMPLEX
2ull:A (ILE31) to (GLY67) MULTIPLE CONFORMATION STRUCTURE OF ALPHA-LYTIC PROTEASE AT 120 K | HYDROLASE, SERINE PROTEASE, ZYMOGEN, PROTEASE PRECURSOR
4k1t:A (GLY17) to (HIS53) GLY-SER-SPLB PROTEASE FROM STAPHYLOCOCCUS AUREUS AT 1.60 A RESOLUTION | CHYMOTRYPSIN-LIKE FOLD, SERINE PROTEASE, EXTRACELLULAR, HYDROLASE
4k1t:B (GLY17) to (HIS53) GLY-SER-SPLB PROTEASE FROM STAPHYLOCOCCUS AUREUS AT 1.60 A RESOLUTION | CHYMOTRYPSIN-LIKE FOLD, SERINE PROTEASE, EXTRACELLULAR, HYDROLASE
1fll:B (LYS429) to (ASP497) MOLECULAR BASIS FOR CD40 SIGNALING MEDIATED BY TRAF3 | TRAF3 WITH CD40 PEPTIDE, TNF SIGNALING, APOPTOSIS
3ufa:B (VAL18) to (ALA53) CRYSTAL STRUCTURE OF THE STAPHYLOCOCCAL SERINE PROTEASE SPLA IN COMPLEX WITH A SPECIFIC PHOSPHONATE INHIBITOR | CHYMOTRYPSIN LIKE FOLD, SERINE PROTEASE, EXTRACELLULAR PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1rjq:A (ASP428) to (ASN459) THE CRYSTAL STRUCTURE OF THE D-AMINOACYLASE MUTANT D366A | TIM BARREL, BETA BARREL, INSERTION, HYDROLASE
1rjr:A (ASP428) to (ASN459) THE CRYSTAL STRUCTURE OF THE D-AMINOACYLASE D366A MUTANT IN COMPLEX WITH 100MM ZNCL2 | TIM BARREL, BETA BARREL, INSERTION, HYDROLASE
1rk5:A (ASP428) to (ASN459) THE D-AMINOACYLASE MUTANT D366A IN COMPLEX WITH 100MM CUCL2 | TIM BARREL, BETA BARREL, INSERTION, HYDROLASE
3v11:B (ILE16) to (LYS67) STRUCTURE OF THE TERNARY INITIATION COMPLEX AIF2:GDPNP:METHIONYLATED INITIATOR TRNA | GTP BINDING MODULE, INITIATOR TRNA CARRIER, GTP AND TRNA, TRANSLATION-RNA COMPLEX
1sky:E (ASN28) to (GLY80) CRYSTAL STRUCTURE OF THE NUCLEOTIDE FREE ALPHA3BETA3 SUB-COMPLEX OF F1-ATPASE FROM THE THERMOPHILIC BACILLUS PS3 | ATP SYNTHASE, F1FO ATP SYNTHASE, F1-ATPASE, ALPHA3BETA3 SUBCOMPLEX OF F1-ATPASE, HYDROLASE
3vb3:B (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE IN APO FORM | HYDROLASE
2vyv:A (ILE167) to (LYS247) STRUCTURE OF E.COLI GAPDH RAT SPERM GAPDH HETEROTETRAMER | CONTRACEPTIVE, OXIDOREDUCTASE, ALPHA CHLOROHYDRIN, GLYCERALDEHYDE-3-PHOSPHATE, NAD, GAPDH, RAT SPERM, CYTOPLASM, GLYCOLYSIS
3vhn:A (GLU152) to (PHE196) Y61G MUTANT OF CELLULASE 12A FROM THERMOTOGA MARITIMA | JELLY ROLL, HYDROLASE, CELLULOSE
1h8h:D (ASN34) to (ASP77) BOVINE MITOCHONDRIAL F1-ATPASE CRYSTALLISED IN THE PRESENCE OF 5MM AMPPNP | ATP PHOSPHORYLASE, ATP PHOSPHORYLASE (H+ TRANSPORTING), ATP SYNTHASE, F1FO ATP SYNTHASE, F1-ATPASE, HYDROLASE
2gx4:A (GLY109) to (TYR154) CRYSTAL STRUCTURE OF SARS CORONAVIRUS 3CL PROTEASE INHIBITOR COMPLEX | SARS, 3CL PROTEASE, INHIBITOR COMPLEX, HYDROLASE
1hdg:O (VAL168) to (VAL244) THE CRYSTAL STRUCTURE OF HOLO-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM THE HYPERTHERMOPHILIC BACTERIUM THERMOTOGA MARITIMA AT 2.5 ANGSTROMS RESOLUTION | OXIDOREDUCTASE (ALDEHY(D)-NAD(A))
2h2z:A (GLY109) to (ASN151) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE WITH AUTHENTIC N AND C-TERMINI | SARS, MAIN PROTEASE, AUTHENTIC N AND C TERMINI, VIRAL PROTEIN
1hja:B (GLN30) to (GLY69) LYS 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH ALPHA-CHYMOTRYPSIN | COMPLEX (HYDROLASE-INHIBITOR), ALPHA-CHYMOTRYPSIN, PROTEIN INHIBITOR, COMPLEX (HYDROLASE-INHIBITOR) COMPLEX
4zzu:A (GLY205) to (GLY240) GEOTRICHUM CANDIDUM CEL7A STRUCTURE COMPLEX WITH THIO-LINKED CELLOTETRAOSE AT 1.4A | CELLOBIOHYDROLASE, THIOCELLOTETRAOSE, HYDROLASE
5a0l:A (PRO78) to (ASP132) N-TERMINAL THIOESTER DOMAIN OF FIBRONECTIN-BINDING PROTEIN SFBI FROM STREPTOCOCCUS PYOGENES | CELL ADHESION, SURFACE-ASSOCIATED PROTEIN, GRAM-POSITIVE, ADHESIN, INTERNAL THIOESTER, THIOESTER DOMAIN
5a0l:B (PRO78) to (ASP132) N-TERMINAL THIOESTER DOMAIN OF FIBRONECTIN-BINDING PROTEIN SFBI FROM STREPTOCOCCUS PYOGENES | CELL ADHESION, SURFACE-ASSOCIATED PROTEIN, GRAM-POSITIVE, ADHESIN, INTERNAL THIOESTER, THIOESTER DOMAIN
3wn7:A (ILE328) to (VAL369) CRYSTAL STRUCTURE OF KEAP1 IN COMPLEX WITH THE N-TERMINAL REGION OF THE NRF2 TRANSCRIPTION FACTOR | BETA-PROPELLER, KELCH MOTIF,DEGRON, TRANSCRIPTION
2xcf:B (GLU32) to (SER66) CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR | PROTEASE, BORONATE INHIBITOR, VIRAL REPRODUCTION, HYDROLASE
2iz4:A (ALA50) to (LEU91) SOLUTION STRUCTURE OF HUMAN AND PORCINE BETA- MICROSEMINOPROTEIN | PYRROLIDONE CARBOXYLIC ACID, INHIBITOR
4mpx:A (GLN45) to (LEU90) HUMAN BETA-TRYPTASE CO-CRYSTAL STRUCTURE WITH [(1,1,3,3- TETRAMETHYLDISILOXANE-1,3-DIYL)DI-1-BENZOTHIENE-4,2-DIYL]BIS({4-[3- (AMINOMETHYL)PHENYL]PIPERIDIN-1-YL}METHANONE) | COFERON, ALPHA-HYDROXYKETONE, SMALL MOLECULE INHIBITOR, DRUG DISCOVERY, SELF-ASSEMBLY, CRYSTAL CATALYSIS, SILANOL, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
5bod:A (SER132) to (PHE176) CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIA PARE INHIBITOR | INHIBITOR, TOPOISOMERASE, PARE, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
5c5o:B (GLN110) to (TYR154) STRUCTURE OF SARS-3CL PROTEASE COMPLEX WITH A PHENYL-BETA-ALANYL (S, R)-N-DECALIN TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDRASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1xfc:B (ARG301) to (PHE342) THE 1.9 A CRYSTAL STRUCTURE OF ALANINE RACEMASE FROM MYCOBACTERIUM TUBERCULOSIS CONTAINS A CONSERVED ENTRYWAY INTO THE ACTIVE SITE | ALPHA-BETA BARREL, BETA-STRUCTURE FOR C-TERMINAL DOMAIN, INTERNAL ALDIMINE FORM, ISOMERASE
2z9k:A (GLN110) to (TYR154) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH JMF1600 | COMPLEX, ATP-BINDING, CYTOPLASM, ENDONUCLEASE, EXONUCLEASE, HELICASE, HYDROLASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RIBOSOMAL FRAMESHIFT, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
2z9k:B (GLY109) to (TYR154) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH JMF1600 | COMPLEX, ATP-BINDING, CYTOPLASM, ENDONUCLEASE, EXONUCLEASE, HELICASE, HYDROLASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RIBOSOMAL FRAMESHIFT, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
2zzg:B (PRO556) to (ILE601) CRYSTAL STRUCTURE OF ALANYL-TRNA SYNTHETASE IN COMPLEX WITH 5''-O-(N-(L-ALANYL)-SULFAMYOXYL) ADENINE WITHOUT OLIGOMERIZATION DOMAIN | LIGASE, HYDROLASE
4ak6:B (ALA314) to (ARG353) BPGH117_H302E MUTANT GLYCOSIDE HYDROLASE | HYDROLASE
3l9z:A (ASP21) to (GLU67) CRYSTAL STRUCTURE OF UREE FROM HELICOBACTER PYLORI (APO FORM) | UREE APO FORM (DIMER), STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, CHAPERONE, NICKEL, NICKEL INSERTION, VIRULENCE, METAL BINDING PROTEIN
3ak5:C (HIS507) to (HIS615) HEMOGLOBIN PROTEASE (HBP) PASSENGER MISSING DOMAIN-2 | AUTOTRANSPORTER, BETA HELIX, MUTANT, HYDROLASE
5dqd:H (ILE89) to (VAL111) STRUCTURE OF S55-5 FAB IN COMPLEX WITH LIPID A CARBOHYDRATE BACKBONE | CARBOHYDRATE BINDING, IMMUNE SYSTEM, ANTIBODY
5dvp:B (ILE188) to (VAL226) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 2 WITH DORIPENEM ADDUCT | PEPTIDOGLYCAN SYNTHESIS ENZYME, CELL WALL ENZYME, TRANSFERASE
1zjc:A (TRP231) to (ASP259) AMINOPEPTIDASE S FROM S. AUREUS | AMINOPEPTIDASE, METALLOPEPTIDASE, HYDROLASE
4b2q:F (ASN35) to (ASP78) MODEL OF THE YEAST F1FO-ATP SYNTHASE DIMER BASED ON SUBTOMOGRAM AVERAGE | HYDROLASE, SUBTOMOGRAM AVERAGE
4b2q:f (ASN35) to (ASP78) MODEL OF THE YEAST F1FO-ATP SYNTHASE DIMER BASED ON SUBTOMOGRAM AVERAGE | HYDROLASE, SUBTOMOGRAM AVERAGE
4b90:B (ASP401) to (ARG442) CRYSTAL STRUCTURE OF WT HUMAN CRMP-5 | SIGNALING PROTEIN, NEUROGENESIS, AXONAL OUTGROWTH, DEVELOPMENTAL PROTEIN
4bqe:A (PHE201) to (GLN226) ARABIDOPSIS THALIANA CYTOSOLIC ALPHA-1,4-GLUCAN PHOSPHORYLASE (PHS2) | TRANSFERASE, TRANSFERASEE, INHIBITORS, CARBOHYDRATE METABOLISM, ALPHA-1, SELF-ASSEMBLY ON SURFACES, SURFACE PLASMON RESONANCE, GOLD NANOPARTICLES
4bqe:B (PHE201) to (GLN226) ARABIDOPSIS THALIANA CYTOSOLIC ALPHA-1,4-GLUCAN PHOSPHORYLASE (PHS2) | TRANSFERASE, TRANSFERASEE, INHIBITORS, CARBOHYDRATE METABOLISM, ALPHA-1, SELF-ASSEMBLY ON SURFACES, SURFACE PLASMON RESONANCE, GOLD NANOPARTICLES
5fns:A (ILE328) to (VAL369) STRUCTURE OF THE KEAP1 KELCH DOMAIN IN COMPLEX WITH A SMALL MOLECULE INHIBITOR. | TRANSCRIPTION, TRASNCRIPTION, KEAP1, NRF2, OXIDATIVE STRESS
3no0:A (ASN574) to (SER616) AQUIFEX AEOLICUS TYPE IIA TOPOISOMERASE C-TERMINAL DOMAIN | DNA TOPOLOGY, TOPOISOMERASE, AQUIFEX AEOLICUS, C-TERMINAL DOMAIN, GYRASE, DNA BINDING PROTEIN, ISOMERASE
3d23:B (GLY109) to (GLY154) MAIN PROTEASE OF HCOV-HKU1 | MAIN PROTEASE, ATP-BINDING, ENDONUCLEASE, EXONUCLEASE, HELICASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC-FINGER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3d23:A (GLY109) to (GLY154) MAIN PROTEASE OF HCOV-HKU1 | MAIN PROTEASE, ATP-BINDING, ENDONUCLEASE, EXONUCLEASE, HELICASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC-FINGER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4csi:B (ARG206) to (GLY241) CRYSTAL STRUCTURE OF THE THERMOSTABLE CELLOBIOHYDROLASE CEL7A FROM THE FUNGUS HUMICOLA GRISEA VAR. THERMOIDEA. | HYDROLASE, GLYCOSIDE HYDROLASE
4tqu:T (MET240) to (ARG284) CRYSTAL STRUCTURE OF A BACTERIAL ABC TRANSPORTER INVOLVED IN THE IMPORT OF THE ACIDIC POLYSACCHARIDE ALGINATE | ABC, SPHINGOMONAS, ALGINATE, TRANSPORTER, TRANSPORT PROTEIN
4tr7:B (ARG169) to (PRO208) CRYSTAL STRUCTURE OF DNA POLYMERASE SLIDING CLAMP FROM MYCOBATERIUM TUBERCULOSIS | SLIDING CLAMP, PROCESSIVITY, DNA BINDING PROTEIN
4tv3:A (ASP434) to (PHE486) ISOLATED P110A SUBUNIT OF PI3KA PROVIDES A PLATFORM FOR STRUCTURE- BASED DRUG DESIGN | LIPID KINASE ACTIVITY, ATPASE ACTIVITY, SURFACE PLASMON RESONANCE (SPR), ISOTHERMAL TITRATION CALORIMETRY (ITC)., TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3phs:A (VAL175) to (LYS225) CRYSTAL STRUCTURE OF GBS52, THE MINOR PILIN IN GRAM-POSITIVE PATHOGEN STREPTOCOCCUS AGALACTIAE | IG-LIKE FOLD, IGG-REV FOLD, GBS52, STREPTOCOCCUS AGALACTIAE, GRAM- POSITIVE PILINS, ADHESIONS, CELL ADHESION, CELL WALL ANCHORING, ADHESION, PILUS SUBUNIT, ISOPEPTIDE BOND, GRAM-POSITIVE BACTERIAL CELL WALL, STRUCTURAL PROTEIN, CELL AHDESION
4e9v:A (ALA1002) to (GLN1040) MULTICOPPER OXIDASE MGLAC (DATA1) | MULTICOPPER OXIDASE, METAL BINDING PROTEIN
5iw7:B (PRO734) to (ARG776) CRYSTAL STRUCTURE OF YEAST TSR1, A PRE-40S RIBOSOME SYNTHESIS FACTOR | TRANSLATIONAL GTPASE RIBOSOME SYNTHESIS, TRANSLATION
5iya:H (GLU89) to (LYS147) HUMAN CORE-PIC IN THE CLOSED STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
4fnr:B (PHE12) to (GLY45) CRYSTAL STRUCTURE OF GH36 ALPHA-GALACTOSIDASE AGAA FROM GEOBACILLUS STEAROTHERMOPHILUS | GLYCOSIDE HYDROLASE, HYDROLASE