4gsk:Y (ILE63) to (LEU96) CRYSTAL STRUCTURE OF AN ATG7-ATG10 CROSSLINKED COMPLEX | UBIQUITIN-LIKE PROTEIN ACTIVATION ENZYME, UBIQUITIN-LIKE PROTEIN TRANSFER ENZYME, PROTEIN TRANSPORT-LIGASE COMPLEX
4wei:A (ALA91) to (ASN127) CRYSTAL STRUCTURE OF THE F4 FIMBRIAL ADHESIN FAEG IN COMPLEX WITH LACTOSE | CO-COMPLEX, LECTIN, ADHESIN, IMMUNOGLOBULIN-LIKE FOLD, STRUCTURAL PROTEIN
4wfv:A (ARG41) to (LYS71) BOVINE ALLERGEN BOS D 2 IN THE MONOCLINIC SPACE GROUP C2. | ALLERGEN, LIPOCALIN
2ohk:A (TYR342) to (ALA368) X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH 1- AMINO-ISOQUINOLINE | ALTERNATIVE SPLICING, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, SIGNAL, TRANSMEMBRANE, ZYMOGEN
1ngl:A (GLY91) to (SER128) HUMAN NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (HNGAL), REGULARISED AVERAGE NMR STRUCTURE | TRANSPORT PROTEIN, MMP-9 COMPONENT, LIPOCALIN
4gyz:G (SER203) to (HIS236) MUS MUSCULUS TDP2 BOUND TO DAMP AND MG2+ | PROTEIN-DNA COMPLEX, DNA REPAIR, 5'-DNA END PROCESSING, ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE DOMAIN, EEP DOMAIN, 5'-DNA END RECOGNITION, HYDROLASE
4gyz:H (SER203) to (HIS236) MUS MUSCULUS TDP2 BOUND TO DAMP AND MG2+ | PROTEIN-DNA COMPLEX, DNA REPAIR, 5'-DNA END PROCESSING, ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE DOMAIN, EEP DOMAIN, 5'-DNA END RECOGNITION, HYDROLASE
3edl:D (LYS90) to (ASP126) KINESIN13-MICROTUBULE RING COMPLEX | KINESIN, KINESIN13, KIN-I, M-KINESIN, MICROTUBULE, TUBULIN, DEPOLYMERIZATION, STRUCTURAL PROTEIN
1ae2:A (ALA11) to (GLU51) MUTANT L32R OF GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN) | SINGLE-STRANDED DNA BINDING PROTEIN, GVP, L32R, MUTANT, DNA-BINDING PROTEIN
3rtn:A (ASN5) to (ASN28) STRUCTURE OF BACE-1 (BETA-SECRETASE) IN COMPLEX WITH 3-(2-AMINO-6-O- TOLYLQUINOLIN-3-YL)-N-CYCLOHEXYLPROPANAMIDE | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2axw:B (ALA22) to (GLY67) STRUCTURE OF DRAD INVASIN FROM UROPATHOGENIC ESCHERICHIA COLI | HOMODIMER, BETA-SANDWICH, IMMUNOGLOBULIN-LIKE FOLD, SWAPPED C- TERMINAL STRANDS, CELL INVASION
2oqz:A (GLY83) to (LYS143) THE CRYSTAL STRUCTURE OF SORTASE B FROM B.ANTHRACIS IN COMPLEX WITH AAEK2 | SORTASE B PROTEIN, INHIBITOR, B.ANTHRACIS, THE GREAT LAKES REGIONAL CENTER OF EXCELLENCE (GLRCE), HYDROLASE
2orz:A (LYS397) to (GLY423) STRUCTURAL BASIS FOR LIGAND BINDING AND HEPARIN MEDIATED ACTIVATION OF NEUROPILIN | NEUROPILIN, VEGF, TUFTSIN, SIGNALING PROTEIN, MEMBRANE PROTEIN
4h4l:A (ARG103) to (ASN146) CRYSTAL STRUCTURE OF TERNARY COMPLEX OF HUTP(HUTP-L-HIS-ZN) | HUTP, ANTI-TERMINATION, HISTIDINE METABOLISM, TRANSCRIPTION, TRANSCRIPTION REGULATION, RNA BINDING PROTEIN
4h4l:C (ARG103) to (ASN146) CRYSTAL STRUCTURE OF TERNARY COMPLEX OF HUTP(HUTP-L-HIS-ZN) | HUTP, ANTI-TERMINATION, HISTIDINE METABOLISM, TRANSCRIPTION, TRANSCRIPTION REGULATION, RNA BINDING PROTEIN
4h4l:F (ARG103) to (ASN146) CRYSTAL STRUCTURE OF TERNARY COMPLEX OF HUTP(HUTP-L-HIS-ZN) | HUTP, ANTI-TERMINATION, HISTIDINE METABOLISM, TRANSCRIPTION, TRANSCRIPTION REGULATION, RNA BINDING PROTEIN
4h4l:G (ARG103) to (ASN146) CRYSTAL STRUCTURE OF TERNARY COMPLEX OF HUTP(HUTP-L-HIS-ZN) | HUTP, ANTI-TERMINATION, HISTIDINE METABOLISM, TRANSCRIPTION, TRANSCRIPTION REGULATION, RNA BINDING PROTEIN
4h4l:H (ARG103) to (ASN146) CRYSTAL STRUCTURE OF TERNARY COMPLEX OF HUTP(HUTP-L-HIS-ZN) | HUTP, ANTI-TERMINATION, HISTIDINE METABOLISM, TRANSCRIPTION, TRANSCRIPTION REGULATION, RNA BINDING PROTEIN
4h4l:I (ARG103) to (ASN146) CRYSTAL STRUCTURE OF TERNARY COMPLEX OF HUTP(HUTP-L-HIS-ZN) | HUTP, ANTI-TERMINATION, HISTIDINE METABOLISM, TRANSCRIPTION, TRANSCRIPTION REGULATION, RNA BINDING PROTEIN
4h4l:J (ARG103) to (ASN146) CRYSTAL STRUCTURE OF TERNARY COMPLEX OF HUTP(HUTP-L-HIS-ZN) | HUTP, ANTI-TERMINATION, HISTIDINE METABOLISM, TRANSCRIPTION, TRANSCRIPTION REGULATION, RNA BINDING PROTEIN
4h4l:K (ARG103) to (ASN146) CRYSTAL STRUCTURE OF TERNARY COMPLEX OF HUTP(HUTP-L-HIS-ZN) | HUTP, ANTI-TERMINATION, HISTIDINE METABOLISM, TRANSCRIPTION, TRANSCRIPTION REGULATION, RNA BINDING PROTEIN
4h4l:L (ARG103) to (ILE145) CRYSTAL STRUCTURE OF TERNARY COMPLEX OF HUTP(HUTP-L-HIS-ZN) | HUTP, ANTI-TERMINATION, HISTIDINE METABOLISM, TRANSCRIPTION, TRANSCRIPTION REGULATION, RNA BINDING PROTEIN
1nrf:A (LEU528) to (ILE555) C-TERMINAL DOMAIN OF THE BACILLUS LICHENIFORMIS BLAR PENICILLIN-RECEPTOR | PENICILLIN-RECEPTOR, BETA-LACTAMASE INDUCTION, BACILLUS LICHENIFORMIS, PENICILLIN-BINDING PROTEIN, MEMBRANE PROTEIN
2b58:A (TYR52) to (LEU91) SSAT WITH COA_SP, SPERMINE DISORDERED, K26R MUTANT | STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, TRANSFERASE
2b5g:A (TYR52) to (MSE97) WILD TYPE SSAT- 1.7A STRUCTURE | STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, TRANSFERASE
2b5g:B (TYR52) to (MSE97) WILD TYPE SSAT- 1.7A STRUCTURE | STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, TRANSFERASE
3en2:A (VAL12) to (GLY56) THREE-DIMENSIONAL STRUCTURE OF THE PROTEIN PRIB FROM RALSTONIA SOLANACEARUM AT THE RESOLUTION 2.3A. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET RSR213C. | PRIB RSR213C NESG X-RAY Q8XZT7 Q8XZT7_RALSO, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, UNKNOWN FUNCTION
3en5:A (PHE278) to (GLU339) TARGETED POLYPHARMACOLOGY: CRYSTAL STRUCTURE OF THE C-SRC KINASE DOMAIN IN COMPLEX WITH PP494, A MULTITARGETED KINASE INHIBITOR | SRC, TYROSINE, KINASE, POLYPHARMACOLOGY, INHIBITOR, MULTITARGET, PHOSPHOINOSITIDE, TRANSFERASE, SIGNALING, PYRAZOLOPYRIMIDINE, KINASE-INHIBITOR COMPLEX, ATP-BINDING, LIPOPROTEIN, MYRISTATE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PROTO-ONCOGENE, SH2 DOMAIN, SH3 DOMAIN, TYROSINE-PROTEIN KINASE
3en7:B (GLY279) to (GLU339) TARGETED POLYPHARMACOLOGY: CRYSTAL STRUCTURE OF THE C-SRC KINASE DOMAIN IN COMPLEX WITH S1, A MULTITARGETED KINASE INHIBITOR | SRC, TYROSINE, KINASE, POLYPHARMACOLOGY, INHIBITOR, MULTITARGET, PHOSPHOINOSITIDE, TRANSFERASE, SIGNALING, PYRAZOLOPYRIMIDINE, KINASE-INHIBITOR COMPLEX, ATP-BINDING, LIPOPROTEIN, MYRISTATE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PROTO-ONCOGENE, SH2 DOMAIN, SH3 DOMAIN, TYROSINE-PROTEIN KINASE
4wtu:A (ASN5) to (ASN28) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH 2-AMINOOXAZOLINE 3-AZA-4- FLUORO-XANTHENE INHIBITOR 22 | ASPARTIC PROTEASE, AMYLOID PRECURSOR PROTEIN, ALZHEIMER'S DISEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4x2l:A (ASN5) to (ASN28) CRYSTAL STRUCTURE OF HUMAN BACE-1 BOUND TO COMPOUND 6 | BETA-SECRETASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3s4d:A (ARG70) to (ARG110) LACTOSE PHOSPHORYLASE IN A TERNARY COMPLEX WITH CELLOBIOSE AND SULFATE | GH94, ALPHA BARREL, LACTOSE PHOSPHORYLASE, DISACCHARIDE PHOSPHORYLASE, TRANSFERASE
2bm3:A (ALA118) to (GLN164) STRUCTURE OF THE TYPE II COHESIN FROM CLOSTRIDIUM THERMOCELLUM SDBA | COHESIN, TYPE 2, CELLULOSOME, DOCKERIN, NUCLEAR PROTEIN
2bnn:A (ILE92) to (THR126) THE STRUCTURE OF HYDROXYPROPYLPHOSPHONIC ACID EPOXIDASE FROM S. WEDMORENIS IN COMPLEX WITH FOSFOMYCIN | OXIDOREDUCTASE, EPOXIDASE, CUPIN, HTH, CATION-DEPENDANT, ZINC, FOSFOMYCIN OXIDOREDUCTASE
4x83:C (GLY284) to (GLY334) CRYSTAL STRUCTURE OF DSCAM1 ISOFORM 7.44, N-TERMINAL FOUR IG DOMAINS | IG FOLD, CELL ADHESION
2bti:A (GLU10) to (ALA36) STRUCTURE-FUNCTION STUDIES OF THE RMSA CSRA POST- TRANSCRIPTIONAL GLOBAL REGULATOR PROTEIN FAMILY REVEALS A CLASS OF RNA-BINDING STRUCTURE | RMSA, CSRA, RNA BINDING PROTEIN
2bti:B (GLU10) to (ALA36) STRUCTURE-FUNCTION STUDIES OF THE RMSA CSRA POST- TRANSCRIPTIONAL GLOBAL REGULATOR PROTEIN FAMILY REVEALS A CLASS OF RNA-BINDING STRUCTURE | RMSA, CSRA, RNA BINDING PROTEIN
2bua:A (ASP104) to (ASP136) CRYSTAL STRUCTURE OF PORCINE DIPEPTIDYL PEPTIDASE IV (CD26) IN COMPLEX WITH A LOW MOLECULAR WEIGHT INHIBITOR. | HYDROLASE/INHIBITOR, DPP-IV, DIABETES MELLITUS, DRUG DESIGN, HYDROLASE, SERINE PROTEASE, AMINOPEPTIDASE, GLYCOPROTEIN, PROTEASE, SIGNAL- ANCHOR, TRANSMEMBRANE, COMPLEX (HYDROLASE/INHIBITOR)
2bua:B (ASP104) to (ASP136) CRYSTAL STRUCTURE OF PORCINE DIPEPTIDYL PEPTIDASE IV (CD26) IN COMPLEX WITH A LOW MOLECULAR WEIGHT INHIBITOR. | HYDROLASE/INHIBITOR, DPP-IV, DIABETES MELLITUS, DRUG DESIGN, HYDROLASE, SERINE PROTEASE, AMINOPEPTIDASE, GLYCOPROTEIN, PROTEASE, SIGNAL- ANCHOR, TRANSMEMBRANE, COMPLEX (HYDROLASE/INHIBITOR)
2bua:C (ASP104) to (ASP136) CRYSTAL STRUCTURE OF PORCINE DIPEPTIDYL PEPTIDASE IV (CD26) IN COMPLEX WITH A LOW MOLECULAR WEIGHT INHIBITOR. | HYDROLASE/INHIBITOR, DPP-IV, DIABETES MELLITUS, DRUG DESIGN, HYDROLASE, SERINE PROTEASE, AMINOPEPTIDASE, GLYCOPROTEIN, PROTEASE, SIGNAL- ANCHOR, TRANSMEMBRANE, COMPLEX (HYDROLASE/INHIBITOR)
2bua:D (ASP104) to (ASP136) CRYSTAL STRUCTURE OF PORCINE DIPEPTIDYL PEPTIDASE IV (CD26) IN COMPLEX WITH A LOW MOLECULAR WEIGHT INHIBITOR. | HYDROLASE/INHIBITOR, DPP-IV, DIABETES MELLITUS, DRUG DESIGN, HYDROLASE, SERINE PROTEASE, AMINOPEPTIDASE, GLYCOPROTEIN, PROTEASE, SIGNAL- ANCHOR, TRANSMEMBRANE, COMPLEX (HYDROLASE/INHIBITOR)
2pgw:D (GLN20) to (PRO55) CRYSTAL STRUCTURE OF A PUTATIVE MUCONATE CYCLOISOMERASE FROM SINORHIZOBIUM MELILOTI 1021 | ENOLASE SUPERFAMILY, MUCONATE CYCLOISOMERASE, OCTAMER, SMALL MOLECULE METABOLISM, PSI-II, NYSGXRC, 9387A, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, ISOMERASE
3scf:B (PRO91) to (THR126) FE(II)-HPPE WITH S-HPP AND NO | CUPIN-FOLD, HYDROXYPROPYLPHOSPHONIC ACID EPOXIDASE, MONONUCLEAR NON- HEME IRON ENZYME, METAL BINDING PROTEIN
3scf:C (ILE92) to (THR126) FE(II)-HPPE WITH S-HPP AND NO | CUPIN-FOLD, HYDROXYPROPYLPHOSPHONIC ACID EPOXIDASE, MONONUCLEAR NON- HEME IRON ENZYME, METAL BINDING PROTEIN
1oec:A (GLY484) to (MET518) FGFR2 KINASE DOMAIN | TRANSFERASE, FGFR2 KINASE DOMAIN, RECEPTOR TYROSINE KINASE,
2bxw:B (PHE102) to (ARG134) CRYSTAL STRUCTURE OF RHOGDI LYS(135,138,141)TYR MUTANT | INHIBITOR, CRYSTAL ENGINEERING, RATIONAL SURFACE MUTAGENESIS, GTPASE ACTIVATION
4i0h:B (ASN11) to (THR39) SPR AND STRUCTURAL ANALYSIS YIELD INSIGHT TOWARDS MECHANISM OF INHIBITION OF BACE INHIBITORS. | BACE, ASP PROTEASE, HYDROLYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4i0i:B (ASN11) to (THR39) SPR AND STRUCTURAL ANALYSIS YIELD INSIGHT TOWARDS MECHANISM OF INHIBITION OF BACE INHIBITORS | BACE, ASPARTIC PROTEASE, HYDROLYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2puu:A (PRO6) to (LYS54) CRYSTAL STRUCTURE OF P38 COMPLEX WITH 1-(5-TERT-BUTYL-2-P- TOLYL-2H-PYRAZOL-3-YL)-3-[4-(6-MORPHOLIN-4-YLMETHYL- PYRIDIN-3-YL)NAPHTHALEN-1-YL]UREA | P38ALPHA, MAP KINASES, CRYSTAL STRUCTURE, DRUG DISCOVERY, TRANSFERASE
4xla:A (LEU663) to (GLU692) TAILSPIKE PROTEIN MUTANT D339A OF E. COLI BACTERIOPHAGE HK620 IN COMPLEX WITH PENTASACCHARIDE | BETA HELIX, PROTEIN-CARBOHYDRATE COMPLEX, PECTIN LYASE FOLD, VIRAL PROTEIN
4xlc:A (LEU663) to (VAL688) TAILSPIKE PROTEIN DOUBLE MUTANT D339N/E372A OF E. COLI BACTERIOPHAGE HK620 | BETA HELIX, PROTEIN-CARBOHYDRATE COMPLEX, PECTIN LYASE FOLD, VIRAL PROTEIN
3fsf:A (THR7) to (LYS54) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH 3-(2,6- DICHLORO-PHENYL)-7-[4-(2-DIETHYLAMINO-ETHOXY)-PHENYLAMINO]- 1-METHYL-3,4-DIHYDRO-1H-PYRIMIDO[4,5-D]PYRIMIDIN-2-ONE | P38; MAP KINASE; SERINE/THREONINE KINASE, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, SIGNALING PROTEIN
1ove:A (THR7) to (LYS54) THE STRUCTURE OF P38 ALPHA IN COMPLEX WITH A DIHYDROQUINOLINONE | MAP KINASE, HYDROPHOBIC POCKET, KINASE DOMAIN, LINKER REGION, TRANSFERASE
4xm3:A (LEU663) to (GLU692) TAILSPIKE PROTEIN MUTANT E372A OF E. COLI BACTERIOPHAGE HK620 IN COMPLEX WITH PENTASACCHARIDE | BETA HELIX, PROTEIN-CARBOHYDRATE COMPLEX, PECTIN LYASE FOLD, METAL BINDING PROTEIN, VIRAL PROTEIN
4xmy:A (LEU663) to (GLU692) TAILSPIKE PROTEIN DOUBLE MUTANT D339A/E372A OF E. COLI BACTERIOPHAGE HK620 IN COMPLEX WITH PENTASACCHARIDE | BETA HELIX, PROTEIN-CARBOHYDRATE COMPLEX, PECTIN LYASE FOLD, VIRAL PROTEIN
4xn3:A (LEU663) to (GLU692) TAILSPIKE PROTEIN MUTANT E372A OF E. COLI BACTERIOPHAGE HK620 IN COMPLEX WITH HEXASACCHARIDE | BETA HELIX, PROTEIN-CARBOHYDRATE COMPLEX, PECTIN LYASE FOLD, VIRAL PROTEIN
4xoa:A (PRO182) to (ARG227) CRYSTAL STRUCTURE OF A FIMH*DSG COMPLEX FROM E.COLI K12 IN SPACE GROUP P1 | TYPE I PILUS, CATCH-BOND, CELL ADHESION, LECTIN, UPEC, BACTERIAL ADHESIN, UTI, MANNOSE, ISOMERASE
4xon:A (LEU663) to (VAL688) TAILSPIKE PROTEIN DOUBLE MUTANT D339N/E372Q OF E. COLI BACTERIOPHAGE HK620 | BETA HELIX, PROTEIN-CARBOHYDRATE COMPLEX, PECTIN LYASE FOLD, VIRAL PROTEIN
4xor:A (LEU663) to (GLU692) TAILSPIKE PROTEIN DOUBLE MUTANT D339N/E372Q OF E. COLI BACTERIOPHAGE HK620 IN COMPLEX WITH PENTASACCHARIDE | BETA HELIX, PROTEIN-CARBOHYDRATE COMPLEX, PECTIN LYASE FOLD, VIRAL PROTEIN, METAL BINDING PROTEIN
4xot:A (LEU663) to (GLU692) TAILSPIKE PROTEIN MUTANT E372Q OF E. COLI BACTERIOPHAGE HK620 IN COMPLEX WITH PENTASACCHARIDE | BETA HELIX, PROTEIN-CARBOHYDRATE COMPLEX, PECTIN LYASE FOLD, VIRAL PROTEIN
1d5a:A (ILE54) to (THR88) CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK. DEPOSITION OF SECOND NATIVE STRUCTURE AT 2.4 ANGSTROM | DNA POLYMERASE, THERMOSTABLE, EXONUCLEASE, RBD DOMAIN, TRANSFERASE
2qd9:A (THR7) to (LYS54) P38 ALPHA MAP KINASE INHIBITOR BASED ON HETEROBICYCLIC SCAFFOLDS | SERINE/THREONINE-PROTEIN KINASE, KINASE, TRANSFERASE, P38 MAP KINASE
2qe8:A (VAL180) to (SER211) CRYSTAL STRUCTURE OF A PUTATIVE HYDROLASE (AVA_4197) FROM ANABAENA VARIABILIS ATCC 29413 AT 1.35 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, HYDROLASE
3g4p:A (ILE207) to (LEU232) OXA-24 BETA-LACTAMASE AT PH 7.5 | B-LACTAMASES, ENZYME MECHANISM, CARBAPENEM, RESISTANCE, HYDROLASE
2ck0:L (SER26) to (TRP50) ANTI-ANTI-IDIOTYPIC ANTIBODY AGAINST HUMAN ANGIOTENSIN II, COMPLEX WITH A SYNTHETIC CYCLIC PEPTIDE | IMMUNOGLOBULIN
1ddt:A (GLN387) to (ALA422) THE REFINED STRUCTURE OF DIMERIC DIPHTHERIA TOXIN AT 2.0 ANGSTROMS RESOLUTION | TOXIN
2qk7:A (SER132) to (GLY157) A COVALENT S-F HETERODIMER OF STAPHYLOCOCCAL GAMMA-HEMOLYSIN | PORE-FORMING TOXIN, BETA-BARREL, PROTEIN-PROTEIN INTERACTION, MOLECULAR PLASTICITY, COVALENT COMPLEX, CYTOLYSIS, HEMOLYSIS, SECRETED, TOXIN
1pfq:B (ASP104) to (ASP136) CRYSTAL STRUCTURE OF HUMAN APO DIPEPTIDYL PEPTIDASE IV / CD26 | MCH_1, HYDROLASE
4iqb:A (GLY61) to (TYR82) HIGH RESOLUTION CRYSTAL STRUCTURE OF C.ELEGANS THYMIDYLATE SYNTHASE | PROTEIN DIMER, DEOXYNUCLEOTIDE BIOSYNTHESIS, TRANSFERASE
4iqb:B (GLY61) to (TYR82) HIGH RESOLUTION CRYSTAL STRUCTURE OF C.ELEGANS THYMIDYLATE SYNTHASE | PROTEIN DIMER, DEOXYNUCLEOTIDE BIOSYNTHESIS, TRANSFERASE
3gbn:H (SER120) to (SER188) CRYSTAL STRUCTURE OF FAB CR6261 IN COMPLEX WITH THE 1918 H1N1 INFLUENZA VIRUS HEMAGGLUTININ | HEMAGGLUTININ, FAB, NEUTRALIZING ANTIBODIES, ANTIBODY, PANDEMIC FLU, CELL MEMBRANE, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, LIPOPROTEIN, MEMBRANE, PALMITATE, TRANSMEMBRANE, VIRION, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
3gc9:A (GLY7) to (LYS54) THE STRUCTURE OF P38BETA C119S, C162S IN COMPLEX WITH A DIHYDROQUINAZOLINONE INHIBITOR | SERINE/THREONINE KINASE, DRUG DESIGN, SELECTIVITY, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
4iqq:B (GLY61) to (TYR82) CRYSTAL STRUCTURE OF C.ELEGANS THYMIDYLATE SYNTHASE IN COMPLEX WITH DUMP AND TOMUDEX | METHYLTRANSFERASE, INHIBITOR, ANTIFOLATE, PROTEIN DIMER, DEOXYNUCLEOTIDE BIOSYNTHESIS, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3gcp:A (THR7) to (LEU55) HUMAN P38 MAP KINASE IN COMPLEX WITH SB203580 | DFG-OUT, TYPE I, SB203580, ALTERNATIVE SPLICING, ATP- BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
2qom:B (GLY1048) to (ALA1093) THE CRYSTAL STRUCTURE OF THE E.COLI ESPP AUTOTRANSPORTER BETA-DOMAIN. | OUTER MEMBRANE PROTEIN, BETA-BARREL, BETA-DOMAIN, AUTOTRANSPORTER, HYDROLASE, PROTEASE, SECRETED, SERINE PROTEASE, TRANSMEMBRANE, VIRULENCE, ZYMOGEN
2qq7:B (GLY279) to (GLU339) CRYSTAL STRUCTURE OF DRUG RESISTANT SRC KINASE DOMAIN WITH IRREVERSIBLE INHIBITOR | SRC KINASE DOMAIN, DRUG RESISTANCE, IRREVERSIBLE INHIBITOR, ALTERNATIVE SPLICING, ATP-BINDING, LIPOPROTEIN, MYRISTATE, NUCLEOTIDE-BINDING, PHOSPHORYLATION, PROTO-ONCOGENE, SH2 DOMAIN, SH3 DOMAIN, TRANSFERASE, TYROSINE-PROTEIN KINASE
3ggw:A (SER26) to (HIS50) CRYSTAL STRUCTURE OF FAB F22-4 IN COMPLEX WITH A CARBOHYDRATE-MIMETIC PEPTIDE | PEPTIDE-CARBOHYDRATE MIMICRY, LPS, SHIGELLA FLEXNERI, ANTIBODY COMPLEX, IMMUNE SYSTEM
1dwn:C (LEU38) to (ALA92) STRUCTURE OF BACTERIOPHAGE PP7 FROM PSEUDOMONAS AERUGINOSA AT 3.7 A RESOLUTION | VIRUS, PHAGE, BACTERIOPHAGE, COAT PROTEIN, ICOSAHEDRAL VIRUS
4iy8:C (VAL191) to (GLY220) BMLP3 - P21 CRYSTAL FORM | LIPOPROTEIN 11 FAMILY, HEMOLYMPH, LIPID BINDING PROTEIN
4iya:A (SER132) to (GLY157) STRUCTURE OF THE Y250A MUTANT OF THE PANTON-VALENTINE LEUCOCIDIN S COMPONENT FROM STAPHYLOCOCCUS AUREUS | STAPHYLOCOCCUS AUREUS, S COMPONENT LEUCOCIDIN, BI-COMPONENT LEUCOTOXIN, BETA-BARREL PORE FORMING TOXIN, TOXIN
4j0o:B (SER132) to (GLY157) STRUCTURE OF THE Y246A MUTANT OF THE PANTON-VALENTINE LEUCOCIDIN S COMPONENT FROM STAPHYLOCOCCUS AUREUS | BI-COMPONENT LEUCOTOXIN, STAPHYLOCOCCUS AUREUS, S COMPONENT LEUCOCIDIN, BETA-BARREL PORE FORMING TOXIN, TOXIN
4j0o:C (SER132) to (GLY157) STRUCTURE OF THE Y246A MUTANT OF THE PANTON-VALENTINE LEUCOCIDIN S COMPONENT FROM STAPHYLOCOCCUS AUREUS | BI-COMPONENT LEUCOTOXIN, STAPHYLOCOCCUS AUREUS, S COMPONENT LEUCOCIDIN, BETA-BARREL PORE FORMING TOXIN, TOXIN
4j0o:D (SER132) to (GLY157) STRUCTURE OF THE Y246A MUTANT OF THE PANTON-VALENTINE LEUCOCIDIN S COMPONENT FROM STAPHYLOCOCCUS AUREUS | BI-COMPONENT LEUCOTOXIN, STAPHYLOCOCCUS AUREUS, S COMPONENT LEUCOCIDIN, BETA-BARREL PORE FORMING TOXIN, TOXIN
4j1k:A (ASN66) to (ASN89) CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-CYANO-PYRIDINE-2- CARBOXYLIC ACID [3-((4R,5R,6S)-2-AMINO-5-FLUORO-4-METHYL-6- TRIFLUOROMETHYL-5,6-DIHYDRO-4H-[1,3]OXAZIN-4-YL)-4-FLUORO-PHENYL]- AMIDE | PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2d4w:A (ALA262) to (ALA309) CRYSTAL STRUCTURE OF GLYCEROL KINASE FROM CELLULOMONAS SP. NT3060 | ALPHA AND BETA PROTEIN, RIBONUCLEASE H-LIKE MOTIF, ACTIN- LIKE ATPASE DOMAIN, TRANSFERASE
2d4w:B (ALA262) to (ALA309) CRYSTAL STRUCTURE OF GLYCEROL KINASE FROM CELLULOMONAS SP. NT3060 | ALPHA AND BETA PROTEIN, RIBONUCLEASE H-LIKE MOTIF, ACTIN- LIKE ATPASE DOMAIN, TRANSFERASE
4j38:A (GLU128) to (SER162) STRUCTURE OF BORRELIA BURGDORFERI OUTER SURFACE PROTEIN E IN COMPLEX WITH FACTOR H DOMAINS 19-20 | BETA BARREL, IMMUNE EVASION, COMPLEMENT REGULATOR BINDING, FH BINDING, MEMBRANE, IMMUNE SYSTEM, ERP PARALOG, LYME DISEASE, BBCRASP-3
1e5p:A (HIS35) to (GLY68) CRYSTAL STRUCTURE OF APHRODISIN, A SEX PHEROMONE FROM FEMALE HAMSTER | LIPOCALIN, PHEROMONE, HAMSTER, CRYSTAL STRUCTURE
1e5p:B (HIS35) to (GLY68) CRYSTAL STRUCTURE OF APHRODISIN, A SEX PHEROMONE FROM FEMALE HAMSTER | LIPOCALIN, PHEROMONE, HAMSTER, CRYSTAL STRUCTURE
1e5p:D (HIS35) to (GLY68) CRYSTAL STRUCTURE OF APHRODISIN, A SEX PHEROMONE FROM FEMALE HAMSTER | LIPOCALIN, PHEROMONE, HAMSTER, CRYSTAL STRUCTURE
2ddr:C (ILE255) to (ASN291) CRYSTAL STRUCTURE OF SPHINGOMYELINASE FROM BACILLUS CEREUS WITH CALCIUM ION | DNASE I LIKE FOLDING, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, HYDROLASE
4j6g:D (GLU86) to (HIS129) CRYSTAL STRUCTURE OF LIGHT AND DCR3 COMPLEX | LIGHT, DCR3, TNF, TNFR, TNF14, STRUCTURAL GENOMICS, PSI-BIOLOGY, NEW HVEM, N-GLYCOSYLATION, MEMBRANE, SECRETED PROTEIN, CYTOKINE, IFN, JELLY-ROLL FOLD, BIND TNF RECEPTOR HVEM AND LTBR, LTBR, PROTEIN STRUCTURE INITIATIVE, ATOMS-TO-ANIMALS: THE IMMUNE FUNCTION NETWORK, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, IMMUNE SYSTEM
3tf4:A (THR515) to (GLY545) ENDO/EXOCELLULASE:CELLOTRIOSE FROM THERMOMONOSPORA | GLYCOSYL HYDROLASE
4jd6:A (ALA45) to (ALA88) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS EIS IN COMPLEX WITH COENZYME A AND TOBRAMYCIN | GNAT, AMINOGLYCOSIDE ACETYLTRANSFERASE, TRANSFERASE
4jd6:B (GLY44) to (ALA88) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS EIS IN COMPLEX WITH COENZYME A AND TOBRAMYCIN | GNAT, AMINOGLYCOSIDE ACETYLTRANSFERASE, TRANSFERASE
4jd6:E (ALA45) to (ALA88) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS EIS IN COMPLEX WITH COENZYME A AND TOBRAMYCIN | GNAT, AMINOGLYCOSIDE ACETYLTRANSFERASE, TRANSFERASE
4jd6:F (GLY44) to (ALA88) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS EIS IN COMPLEX WITH COENZYME A AND TOBRAMYCIN | GNAT, AMINOGLYCOSIDE ACETYLTRANSFERASE, TRANSFERASE
1q9k:A (SER26) to (TRP50) S25-2 FAB UNLIGANDED 1 | ANTIGEN-BINDING FRAGMENT, FAB, ANTI-CARBOHYDRATE, ANTI-LPS, ANTIBODY, IMMUNOGLOBULIN, IMMUNE SYSTEM
1q9l:A (SER26) to (TRP50) S25-2 FAB UNLIGANDED 2 | ANTIGEN-BINDING FRAGMENT, FAB, ANTI-CARBOHYDRATE, ANTI-LPS, ANTIBODY, IMMUNOGLOBULIN, IMMUNE SYSTEM
1q9l:C (SER26) to (TRP50) S25-2 FAB UNLIGANDED 2 | ANTIGEN-BINDING FRAGMENT, FAB, ANTI-CARBOHYDRATE, ANTI-LPS, ANTIBODY, IMMUNOGLOBULIN, IMMUNE SYSTEM
2duo:A (GLY244) to (GLN275) CRYSTAL STRUCTURE OF VIP36 EXOPLASMIC/LUMENAL DOMAIN, CA2+- BOUND FORM | BETA SANDWICH, CARBOHYDRATE BINDING PROTEIN, CARGO RECEPTOR, PROTEIN TRANSPORT
2duo:B (GLY244) to (GLN275) CRYSTAL STRUCTURE OF VIP36 EXOPLASMIC/LUMENAL DOMAIN, CA2+- BOUND FORM | BETA SANDWICH, CARBOHYDRATE BINDING PROTEIN, CARGO RECEPTOR, PROTEIN TRANSPORT
2duq:A (GLY244) to (GLN275) CRYSTAL STRUCTURE OF VIP36 EXOPLASMIC/LUMENAL DOMAIN, CA2+/MAN-BOUND FORM | BETA SANDWICH, CARBOHYDRATE BINDING PROTEIN, CARGO RECEPTOR, PROTEIN TRANSPORT
2dur:A (GLY244) to (GLN275) CRYSTAL STRUCTURE OF VIP36 EXOPLASMIC/LUMENAL DOMAIN, CA2+/MAN2-BOUND FORM | BETA SANDWICH, CARBOHYDRATE BINDING PROTEIN, CARGO RECEPTOR, PROTEIN TRANSPORT
4ydd:D (ALA153) to (CYS197) CRYSTAL STRUCTURE OF THE PERCHLORATE REDUCTASE PCRAB FROM AZOSPIRA SUILLUM PS | ELECTRON-SHUTTLING PROTEIN, OXIDOREDUCTASE
4ydj:H (PHE108) to (ASP144) CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY 44- VRC13.01 IN COMPLEX WITH HIV-1 CLADE AE STRAIN 93TH057 GP120 | ANTIBODY, HIV-1, IMMUNE SYSTEM
4yej:A (LEU663) to (GLU692) TAILSPIKE PROTEIN DOUBLE MUTANT D339A/E372Q OF E. COLI BACTERIOPHAGE HK620 IN COMPLEX WITH PENTASACCHARIDE | BETA HELIX, PROTEIN-CARBOHYDRATE COMPLEX, PECTIN LYASE FOLD, METAL BINDING PROTEIN
2rk9:B (GLU104) to (GLN134) THE CRYSTAL STRUCTURE OF A GLYOXALASE/BLEOMYCIN RESISTANCE PROTEIN/DIOXYGENASE SUPERFAMILY MEMBER FROM VIBRIO SPLENDIDUS 12B01 | 11005R, GLYOXALASE/BLEOMYCIN RESISTANCE PROTEIN/DIOXYGENASE SUPERFAMILY, NYSGXRC, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE II, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, PSI-2, OXIDOREDUCTASE
3tud:A (LEU377) to (LEU404) CRYSTAL STRUCTURE OF SYK KINASE DOMAIN WITH N-(4-METHYL-3-(8-METHYL-7- OXO-2-(PHENYLAMINO)-7,8-DIHYDROPYRIDO[2,3-D]PYRIMIDIN-6-YL)PHENYL)-3- (TRIFLUOROMETHYL)BENZAMIDE | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3tuc:A (LEU377) to (LYS405) CRYSTAL STRUCTURE OF SYK KINASE DOMAIN WITH 1-BENZYL-N-(5-(6,7- DIMETHOXYQUINOLIN-4-YLOXY)PYRIDIN-2-YL)-2-OXO-1,2-DIHYDROPYRIDINE-3- CARBOXAMIDE | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2e22:A (ASP584) to (ASN623) CRYSTAL STRUCTURE OF XANTHAN LYASE IN COMPLEX WITH MANNOSE | XANTHAN, MANNOSE, POLYSACCHARIDE LYASE, LYASE
1ezx:C (CYS42) to (LYS107) CRYSTAL STRUCTURE OF A SERPIN:PROTEASE COMPLEX | PROTEASE-INHIBITOR COMPLEX, SERPIN, ALPHA-1-ANTITRYPSIN, TRYPSIN, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1f0l:A (THR386) to (ALA422) 1.55 ANGSTROM CRYSTAL STRUCTURE OF WILD TYPE DIPHTHERIA TOXIN | BACTERIAL TOXIN, ADP-RIBOSYLATION, TRANSMEMBRANE
2tpt:A (GLY368) to (LYS405) STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE | THYMIDINE PHOSPHORYLASE, TRANSFERASE, SALVAGE PATHWAY
4yiy:A (GLU75) to (PRO106) STRUCTURE OF MRB1590 BOUND TO AMP-PNP | KRNA EDITING, MRB1590, ATPASE, RNA BINDING, RNA BINDING PROTEIN
3h6e:A (GLU249) to (MSE297) THE CRYSTAL STRUCTURE OF A CARBOHYDRATE KINASE FROM NOVOSPHINGOBIUM AROMATICIVORANS | CARBOHYDRATE KINASE, NOVOSPHINGOBIUM AROMATICIVORANS,STRAIN DSM 12444, SGX, 11200I, KINASE, TRANSFERASE, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
1qun:L (THR184) to (ARG227) X-RAY STRUCTURE OF THE FIMC-FIMH CHAPERONE ADHESIN COMPLEX FROM UROPATHOGENIC E.COLI | CHAPERONE ADHESIN DONOR STRAND COMPLEMENTATION, CHAPERONE/STRUCTURAL PROTEIN COMPLEX
1qun:P (THR184) to (ARG227) X-RAY STRUCTURE OF THE FIMC-FIMH CHAPERONE ADHESIN COMPLEX FROM UROPATHOGENIC E.COLI | CHAPERONE ADHESIN DONOR STRAND COMPLEMENTATION, CHAPERONE/STRUCTURAL PROTEIN COMPLEX
1f8n:A (SER111) to (PHE144) LIPOXYGENASE-1 (SOYBEAN) AT 100K, NEW REFINEMENT | DIOXYGENASE, LIPOXYGENASE, METALLOPROTEIN, FATTY ACIDS, OXIDOREDUCTASE
4jut:C (ILE88) to (ARG122) CRYSTAL STRUCTURE OF A MUTANT FRAGMENT OF HUMAN HSPB6 | SMALL HEAT SHOCK PROTEIN, ALPHA-CRYSTALLIN DOMAIN, CHAPERONE
1r19:B (SER415) to (ASN456) CRYSTAL STRUCTURE ANALYSIS OF S.EPIDERMIDIS ADHESIN SDRG BINDING TO FIBRINOGEN (APO STRUCTURE) | MSCRAMM, SDRG NATIVE, CELL ADHESION
3u73:U (ASP163) to (GLY240) CRYSTAL STRUCTURE OF STABILIZED HUMAN UPAR MUTANT IN COMPLEX WITH ATF | GLYCOSYLATION, HYDROLASE-HYDROLASE RECEPTOR COMPLEX
3u74:U (THR164) to (GLY240) CRYSTAL STRUCTURE OF STABILIZED HUMAN UPAR MUTANT | GLYCOSYLATION, HYDROLASE RECEPTOR
3u7u:B (CYS568) to (PRO612) CRYSTAL STRUCTURE OF EXTRACELLULAR REGION OF HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 4 IN COMPLEX WITH NEUREGULIN-1 BETA | SIGNALING PROTEIN, TRANSFERASE-TRANSFERASE REGULATOR COMPLEX, GLYCOSYLATION
3heg:A (THR7) to (LEU55) P38 IN COMPLEX WITH SORAFENIB | TRANSFERASES, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
1fgm:A (SER111) to (PHE144) LIPOXYGENASE-1 (SOYBEAN) AT 100K, N694H MUTANT | DIOXYGENASE, LIPOXYGENASE, METALLOPROTEIN, FATTY ACIDS, OXIDOREDUCTASE
4k2r:A (GLY345) to (LYS372) STRUCTURAL BASIS FOR ACTIVATION OF ZAP-70 BY PHOSPHORYLATION OF THE SH2-KINASE LINKER | KINASE DOMAIN, SH2 DOMAIN, TRANSFERASE, ATP BINDING, CYTOPLAM
3udg:C (ASP141) to (ARG184) STRUCTURE OF DEINOCOCCUS RADIODURANS SSB BOUND TO SSDNA | SSB, OB FOLD, BETA-BARREL, SINGLE-STRANDED DNA-BINDING, DNA BINDING PROTEIN-DNA COMPLEX
3udw:C (THR35) to (ALA67) CRYSTAL STRUCTURE OF THE IMMUNORECEPTOR TIGIT IN COMPLEX WITH POLIOVIRUS RECEPTOR (PVR/CD155/NECL-5) D1 DOMAIN | PVR TIGIT IGSF SIGNAL TRANSDUCTION IMMUNOLOGY, IGSF, CELL SURFACE RECEPTOR SIGNALLING, GLYCOSYLATION, MEMBRANE PROTEIN, SIGNALING PROTEIN
2ew0:A (HIS8) to (ASN43) X-RAY CRYSTAL STRUCTURE OF PROTEIN Q6FF54 FROM ACINETOBACTER SP. ADP1. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ASR1. | Q5FF54, ASR1, NESG, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, UNKNOWN FUNCTION
2v5m:A (GLY283) to (GLY333) STRUCTURAL BASIS FOR DSCAM ISOFORM SPECIFICITY | DOWN SYNDROME CELL ADHESION MOLECULE DSCAM, NEUROBIOLOGY SPL, IMMUNOGLOBULIN DOMAIN, CELL ADHESION, MEMBRANE, DEVELOPMENTAL PROTEIN
3hkw:A (LEU362) to (TYR383) HCV NS5B GENOTYPE 1A IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 6 | HCV POLYMERASE, SUBTYPE 1A, 1,5-BENZODIAZEPINE, TRANSFERASE
1fq7:A (GLY0) to (LYS28) X-RAY STRUCTURE OF INHIBITOR CP-72,647 BOUND TO SACCHAROPEPSIN | HYDROPHOBIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1reo:A (GLY344) to (GLY375) L-AMINO ACID OXIDASE FROM AGKISTRODON HALYS PALLAS | L-AMINO ACID OXIDASE, OXIDOREDUCTASE
1ft0:A (SER101) to (ARG134) CRYSTAL STRUCTURE OF TRUNCATED HUMAN RHOGDI K113A MUTANT | IMMUNOGLOBULIN FOLD, BETA SANDWICH MOTIF, ISOPRENYL-BINDING DOMAIN, GDP-DISSOCIATION INHIBITOR OF RHO GTPASES, SIGNALING PROTEIN INHIBITOR
1ft3:A (SER101) to (ARG134) CRYSTAL STRUCTURE OF TRUNCATED RHOGDI K141A MUTANT | IMMUNOGLOBULIN FOLD, BETA SANDWICH MOTIF, ISOPRENYL-BINDING DOMAIN, GDP-DISSOCIATION INHIBITOR OF RHO GTPASES, SIGNALING PROTEIN INHIBITOR
4k8x:A (LYS53) to (ASN88) BINARY COMPLEX OF 9N DNA POLYMERASE IN THE REPLICATIVE STATE | DNA POLYMERASE, BINARY COMPLEX, TRANSFERASE-DNA COMPLEX
4k8z:A (ILE54) to (THR88) KOD POLYMERASE IN BINARY COMPLEX WITH DSDNA | DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
2f3e:A (ASN5) to (THR33) CRYSTAL STRUCTURE OF THE BACE COMPLEX WITH AXQ093, A MACROCYCLIC INHIBITOR | BETA-SECRETASE, MEMAPSIN2, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, MACROCYCLIC PEPTIDOMIMETIC INHIBITOR, HYDROLASE
2f3e:B (ASN5) to (THR33) CRYSTAL STRUCTURE OF THE BACE COMPLEX WITH AXQ093, A MACROCYCLIC INHIBITOR | BETA-SECRETASE, MEMAPSIN2, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, MACROCYCLIC PEPTIDOMIMETIC INHIBITOR, HYDROLASE
2f3e:C (ASN5) to (THR33) CRYSTAL STRUCTURE OF THE BACE COMPLEX WITH AXQ093, A MACROCYCLIC INHIBITOR | BETA-SECRETASE, MEMAPSIN2, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, MACROCYCLIC PEPTIDOMIMETIC INHIBITOR, HYDROLASE
2f3f:B (ASN5) to (THR33) CRYSTAL STRUCTURE OF THE BACE COMPLEX WITH BDF488, A MACROCYCLIC INHIBITOR | BETA-SECRETASE, MEMAPSIN2, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, MACROCYCLIC PEPTIDOMIMETIC INHIBITOR, HYDROLASE
2f5i:A (TYR52) to (MET97) X-RAY STRUCTURE OF SPERMIDINE/SPERMINE N1-ACETYLTRANSFERASE (SAT) FROM HOMO SAPIENS | BETA-ALPHA-BARRELS, TRANSFERASE
2f5i:B (TYR52) to (MET97) X-RAY STRUCTURE OF SPERMIDINE/SPERMINE N1-ACETYLTRANSFERASE (SAT) FROM HOMO SAPIENS | BETA-ALPHA-BARRELS, TRANSFERASE
1rrh:A (SER129) to (PHE162) SOYBEAN LIPOXYGENASE (LOX-3) AT AMBIENT TEMPERATURES AT 2.0 A RESOLUTION | OXIDOREDUCTASE, IRON METALLOPROTEIN, LIPOXYGENASE
4ke0:C (ASN5) to (ASN28) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH HYDROXYETHYLAMINE- MACROCYCLIC INHIBITOR 13 | ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, AMYLOID PRECURSOR PROTEIN (APP), HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ke1:A (ASN5) to (ASN28) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH HYDROXYETHYLAMINE- MACROCYCLIC INHIBITOR 19 | ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, AMYLOID PRECURSOR PROTEIN (APP), HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2fck:A (GLY69) to (GLY103) STRUCTURE OF A PUTATIVE RIBOSOMAL-PROTEIN-SERINE ACETYLTRANSFERASE FROM VIBRIO CHOLERAE. | VIBRIO CHOLERAE, SERINE ACETYLTRANSFERASE, RIBOSOMAL-PROTEIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
2fe8:C (GLY194) to (TYR234) SARS CORONAVIRUS PAPAIN-LIKE PROTEASE: STRUCTURE OF A VIRAL DEUBIQUITINATING ENZYME | PROTEASE, HYDROLASE
2vdt:A (LYS215) to (GLU262) CRYSTALLOGRAPHIC STRUCTURE OF LEVANSUCRASE FROM BACILLUS SUBTILIS MUTANT S164A | BETA-PROPELLER, GLYCOSYLTRANSFERASE, GLYCOSIDE HYDROLASE, LEVAN, SECRETED, TRANSFERASE, LEVANSUCRASE
4khm:B (LEU362) to (ASP387) HCV NS5B GT1A WITH GSK5852 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DEPENDENT RNA POLYMERASE, RNA DIRECTED RNA POLYMERASE, REPLICATION- REPLICATION INHIBITOR COMPLEX
1g8k:A (ALA14) to (VAL86) CRYSTAL STRUCTURE ANALYSIS OF ARSENITE OXIDASE FROM ALCALIGENES FAECALIS | OXIDASE, ARSENITE, MOLYBDOPTERIN, [3FE-4S] CLUSTER, [2FE-2S] CLUSTER, RIESKE, OXIDOREDUCTASE
1g8k:C (ALA14) to (VAL86) CRYSTAL STRUCTURE ANALYSIS OF ARSENITE OXIDASE FROM ALCALIGENES FAECALIS | OXIDASE, ARSENITE, MOLYBDOPTERIN, [3FE-4S] CLUSTER, [2FE-2S] CLUSTER, RIESKE, OXIDOREDUCTASE
1g8k:E (ALA14) to (VAL86) CRYSTAL STRUCTURE ANALYSIS OF ARSENITE OXIDASE FROM ALCALIGENES FAECALIS | OXIDASE, ARSENITE, MOLYBDOPTERIN, [3FE-4S] CLUSTER, [2FE-2S] CLUSTER, RIESKE, OXIDOREDUCTASE
1g8k:G (ALA14) to (VAL86) CRYSTAL STRUCTURE ANALYSIS OF ARSENITE OXIDASE FROM ALCALIGENES FAECALIS | OXIDASE, ARSENITE, MOLYBDOPTERIN, [3FE-4S] CLUSTER, [2FE-2S] CLUSTER, RIESKE, OXIDOREDUCTASE
1rz2:A (GLY83) to (LYS143) 1.6A CRYSTAL STRUCTURE OF THE PROTEIN BA4783/Q81L49 (SIMILAR TO SORTASE B) FROM BACILLUS ANTHRACIS. | SORTASE B PROTEIN, B. ANTHRACIS, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
4kin:C (THR7) to (LYS54) CRYSTAL STRUCTURE OF MITOGEN-ACTIVATED PROTEIN KINASE 14 (P38-H5) COMPLEX WITH 5-(2-CHLOROPHENYL)-N-(5-(CYCLOPROPYLCARBAMOYL)-2- METHYLPHENYL)-2-THIOPHENECARBOXAMIDE | SERINE/THREONINE-PROTEIN KINASE, KINASE, TRANSFERASE, P38 MAP KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4kip:A (THR7) to (LYS54) CRYSTAL STRUCTURE OF MITOGEN-ACTIVATED PROTEIN KINASE 14 (P38-H5) COMPLEX WITH 2-(2-CHLOROPHENYL)-N-(5-(CYCLOPROPYLCARBAMOYL)-2- METHYLPHENYL)-1,3-THIAZOLE-5-CARBOXAMIDE | SERINE/THREONINE-PROTEIN KINASE, KINASE, TRANSFERASE, P38 MAP KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4kip:B (THR7) to (LYS54) CRYSTAL STRUCTURE OF MITOGEN-ACTIVATED PROTEIN KINASE 14 (P38-H5) COMPLEX WITH 2-(2-CHLOROPHENYL)-N-(5-(CYCLOPROPYLCARBAMOYL)-2- METHYLPHENYL)-1,3-THIAZOLE-5-CARBOXAMIDE | SERINE/THREONINE-PROTEIN KINASE, KINASE, TRANSFERASE, P38 MAP KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2vij:A (ASN66) to (ASN89) HUMAN BACE-1 IN COMPLEX WITH 3-(1,1-DIOXIDOTETRAHYDRO-2H-1, 2-THIAZIN-2-YL)-5-(ETHYLAMINO)-N-((1S,2R)-2-HYDROXY-1-( PHENYLMETHYL)-3-(1,2,3,4-TETRAHYDRO-1-NAPHTHALENYLAMINO) PROPYL)BENZAMIDE | ALTERNATIVE SPLICING, BETA-SITE APP CLEAVING ENZYME, BETA-SECRETASE, ASPARTYL PROTEASE, ASP-2, BACE-1, ZYMOGEN, PROTEASE, MEMBRANE, HYDROLASE, MEMAPSIN-2, GLYCOPROTEIN, TRANSMEMBRANE
2vjj:A (LEU663) to (VAL688) TAILSPIKE PROTEIN OF E.COLI BACTERIOPHAGE HK620 IN COMPLEX WITH HEXASACCHARIDE | VIRAL PROTEIN, ENDO-N-ACETYLGLUCOSAMINIDASE, VIRAL ADHESION PROTEIN, RIGHT-HANDED PARALLEL BETA-HELIX, HYDROLASE, TAILSPIKE
4z6x:A (GLY144) to (ASP187) THE 1.68-ANGSTROM CRYSTAL STRUCTURE OF ACITIVE-SITE METAL-FREE PQQB FROM PSEUDOMONAS PUTIDA | PQQB, PQQ, PYRROLOQUINOLINE QUINONE, METALLO-BETA-LACTAMASE, LACTAMASE, HYDROLASE
3hr9:A (ASP202) to (LEU228) THE TRUNCATED FIBROBACTER SUCCINOGENES 1,3-1,4-BETA-D- GLUCANASE F40I MUTANT | 1,3-1,4-BETA-D-GLUCANASE, CARBOHYDRATE CH-PI STACKING INTERACTIONS, TRIS INHIBITION, HYDROLASE, GLYCOSIDASE
3hub:A (THR7) to (LYS54) HUMAN P38 MAP KINASE IN COMPLEX WITH SCIOS-469 | DFG-IN, GLYCINE-RICH LOOP, SCIOS-469, ALTERNATIVE SPLICING, ATP- BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3hvg:C (ASN5) to (THR33) STRUCTURE OF BACE (BETA SECRETASE) IN COMPLEX WITH EV0 | PROTEASE, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, AMYLOID PRECURSOR PROTEIN SECRETASES, ASPARTIC ENDOPEPTIDASES, FRAGMENT- BASED DRUG DESIGN, FLUORESCENCE POLARISATION, DISULFIDE BOND, TRANSMEMBRANE, ZYMOGEN
4zez:A (HIS188) to (TRP244) CRYSTAL STRUCTURE OF HCV 1406 TCR/HCV NS3: 1406-1415/HLA-A2 COMPLEX | HCV TCR, HLA-A2, HCV NS3:1406-1415 PEPTIDE, DECAPEPTIDE, PROTEIN BINDING, IMMUNE SYSTEM COMPLEX, PROTEIN BINDING-IMMUNE SYSTEM COMPLEX
1sdd:B (GLY1705) to (ALA1766) CRYSTAL STRUCTURE OF BOVINE FACTOR VAI | COAGULATION, COPPER-BINDING PROTEIN, COFACTOR, BLOOD CLOTTING
3hzk:A (SER26) to (TRP50) CRYSTAL STRUCTURE OF S73-2 ANTIBODY IN COMPLEX WITH ANTIGEN KDO(2.4)KDO | ANTIBODY, FAB, IGG, CARBOHYDRATE, IMMUNE SYSTEM
3hzm:A (SER26) to (TRP50) CRYSTAL STRUCTURE OF S73-2 ANTIBODY IN COMPLEX WITH ANTIGEN KDO | ANTIBODY, FAB, IGG, CARBOHYDRATE, IMMUNE SYSTEM
3hzv:A (SER26) to (TRP50) CRYSTAL STRUCTURE OF S73-2 ANTIBODY IN COMPLEX WITH ANTIGEN KDO(2.8) KDO(2.4)KDO | ANTIBODY, FAB, IGG, CARBOHYDRATE, IMMUNE SYSTEM
2g21:B (SER3) to (LYS29) KETOPIPERAZINE-BASED RENIN INHIBITORS: OPTIMIZATION OF THE "C" RING | PROTEIN-LIGAND COMPLEXES, HYDROLASE
3i1f:B (ARG384) to (MET407) GAMMA-SUBUNIT OF THE TRANSLATION INITIATION FACTOR 2 FROM S. SOLFATARICUS IN COMPLEX WITH GPP(CH2)P | AIF2, INITIATION FACTOR 2 GAMMA SUBUNIT, INITIATION OF THE TRANSLATION, NUCLEOTIDE BINDING, GDPCP, MRNA BINDING, GTP-BINDING, INITIATION FACTOR, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, TRANSLATION
2vqz:D (THR329) to (GLY359) STRUCTURE OF THE CAP-BINDING DOMAIN OF INFLUENZA VIRUS POLYMERASE SUBUNIT PB2 WITH BOUND M7GTP | RNA-DEPENDENT RNA POLYMERASE, TRANSCRIPTION, PB2 SUBUNIT, INFLUENZA VIRUS, CAP-BINDING DOMAIN
2vqz:E (THR329) to (GLY359) STRUCTURE OF THE CAP-BINDING DOMAIN OF INFLUENZA VIRUS POLYMERASE SUBUNIT PB2 WITH BOUND M7GTP | RNA-DEPENDENT RNA POLYMERASE, TRANSCRIPTION, PB2 SUBUNIT, INFLUENZA VIRUS, CAP-BINDING DOMAIN
2vr3:B (TYR372) to (ASN401) STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF FIBRINOGEN BINDING TO CLFA FROM STAPHYLOCCCUS AUREUS | PLATELET AGGREGATION, PEPTIDOGLYCAN-ANCHOR, CELL ADHESION, STAPHYLOCOCCUS AUREUS, FIBRINOGEN GAMMA-CHAIN, SECRETED, CELL WALL, VIRULENCE, CLUMPING FACTOR
4kub:A (SER52) to (ALA84) CRYSTAL STRUCTURE OF A GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794 IN COMPLEX WITH COA | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, GNAT, ACETYLTRANSFERASE, TRANSFERASE
2g5t:A (PRO181) to (ASP230) CRYSTAL STRUCTURE OF HUMAN DIPEPTIDYL PEPTIDASE IV (DPPIV) COMPLEXED WITH CYANOPYRROLIDINE (C5-PRO-PRO) INHIBITOR 21AG | SERINE PEPTIDASE, BETA-PROPELLER, HYDROLASE
2g5t:B (PRO181) to (ASP230) CRYSTAL STRUCTURE OF HUMAN DIPEPTIDYL PEPTIDASE IV (DPPIV) COMPLEXED WITH CYANOPYRROLIDINE (C5-PRO-PRO) INHIBITOR 21AG | SERINE PEPTIDASE, BETA-PROPELLER, HYDROLASE
1snu:A (ILE369) to (ILE393) CRYSTAL STRUCTURE OF THE UNPHOSPHORYLATED INTERLEUKIN-2 TYROSINE KINASE CATALYTIC DOMAIN | PROTEIN KINASE, IMMUNOLOGY, TRANSFERASE
2g63:A (PRO181) to (ASP230) CRYSTAL STRUCTURE OF HUMAN DIPEPTIDYL PEPTIDASE IV (DPPIV) COMPLEXED WITH CYANOPYRROLIDINE (C5-PRO-PRO) INHIBITOR 24B | SERINE PEPTIDASE, BETA-PROPELLER, HYDROLASE
2g63:B (PRO181) to (ASP230) CRYSTAL STRUCTURE OF HUMAN DIPEPTIDYL PEPTIDASE IV (DPPIV) COMPLEXED WITH CYANOPYRROLIDINE (C5-PRO-PRO) INHIBITOR 24B | SERINE PEPTIDASE, BETA-PROPELLER, HYDROLASE
2g63:C (PRO181) to (ASP230) CRYSTAL STRUCTURE OF HUMAN DIPEPTIDYL PEPTIDASE IV (DPPIV) COMPLEXED WITH CYANOPYRROLIDINE (C5-PRO-PRO) INHIBITOR 24B | SERINE PEPTIDASE, BETA-PROPELLER, HYDROLASE
2g63:D (PRO181) to (ASP230) CRYSTAL STRUCTURE OF HUMAN DIPEPTIDYL PEPTIDASE IV (DPPIV) COMPLEXED WITH CYANOPYRROLIDINE (C5-PRO-PRO) INHIBITOR 24B | SERINE PEPTIDASE, BETA-PROPELLER, HYDROLASE
1sru:C (ASP3017) to (GLY3061) CRYSTAL STRUCTURE OF FULL LENGTH E. COLI SSB PROTEIN | REPLICATION
1sru:D (ASP4017) to (GLY4061) CRYSTAL STRUCTURE OF FULL LENGTH E. COLI SSB PROTEIN | REPLICATION
3i7h:A (LYS709) to (ILE740) CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF HBX | DDB1, HBV, X PROTEIN, H-BOX MOTIF, CYTOPLASM, DNA DAMAGE, DNA REPAIR, DNA-BINDING, HOST-VIRUS INTERACTION, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, UBL CONJUGATION, UBL CONJUGATION PATHWAY, ACTIVATOR, APOPTOSIS, MITOCHONDRION, TRANSCRIPTION, TRANSCRIPTION REGULATION, PROTEIN BINDING/VIRAL PROTEIN COMPLEX
2vwk:A (ILE54) to (THR88) URACIL RECOGNITION IN ARCHAEAL DNA POLYMERASES CAPTURED BY X-RAY CRYSTALLOGRAPHY. V93Q POLYMERASE VARIANT | DNA REPLICATION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDYLTRANSFERASE, DNA-DIRECTED DNA POLYMERASE, TRANSFERASE, EXONUCLEASE, DNA-BINDING, DNA POLYMERASE, URACIL, ARCHAEA, NUCLEASE, HYDROLASE, DNA REPAIR
3i7p:A (LYS709) to (ILE740) CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDR40A | DDB1, WDR40A, DCAF12, H-BOX MOTIF, CYTOPLASM, DNA DAMAGE, DNA REPAIR, DNA-BINDING, HOST-VIRUS INTERACTION, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, UBL CONJUGATION, UBL CONJUGATION PATHWAY, WD REPEAT
3i8c:A (LYS709) to (ILE740) CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDR21A | DDB1, WDR21A, DCAF4, H-BOX MOTIF, CYTOPLASM, DNA DAMAGE, DNA REPAIR, DNA-BINDING, HOST-VIRUS INTERACTION, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, UBL CONJUGATION, UBL CONJUGATION PATHWAY, ALTERNATIVE SPLICING, WD REPEAT
3i8e:A (LYS709) to (THR745) CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDR42A | DDB1, WDR42A, H326, DCAF8, H-BOX MOTIF, DNA DAMAGE, DNA REPAIR, DNA- BINDING, HOST-VIRUS INTERACTION, NUCLEUS, PHOSPHOPROTEIN, UBL CONJUGATION PATHWAY, WD REPEAT, PROTEIN BINDING
2ggl:D (THR111) to (GLU146) THE MUTANT A222C OF AGROBACTERIUM RADIOBACTER N-CARBAMOYL-D-AMINO ACID AMIDOHYDROLASE | N-CARBAMOYL-D-AMINO-ACID AMIDOHYDROLASE, HYDROLASE
4zkq:A (GLU69) to (GLY111) VIRAL CHEMOKINE BINDING PROTEIN R17 ENCODED BY RODENT GAMMAHERPESVIRUS PERU ( RHVP) | CHEMOKINE BINDING PROTEIN, VIRAL PROTEIN
3ib5:A (GLN149) to (SER194) CRYSTAL STRUCTURE OF SEX PHEROMONE PRECURSOR (YP_536235.1) FROM LACTOBACILLUS SALIVARIUS SUBSP. SALIVARIUS UCC118 AT 1.35 A RESOLUTION | YP_536235.1, SEX PHEROMONE PRECURSOR, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LIPOPROTEIN, CAMS SEX PHEROMONE CAM373 PRECURSOR, HORMONE
3id2:B (LYS270) to (VAL302) CRYSTAL STRUCTURE OF RSEP PDZ2 DOMAIN | HYDROLASE, CELL INNER MEMBRANE, CELL MEMBRANE, MEMBRANE, METAL-BINDING, METALLOPROTEASE, PROTEASE, TRANSMEMBRANE, ZINC
4znr:A (GLU247) to (ASP305) CRYSTAL STRUCTURE OF DLN1 COMPLEXED WITH MAN(ALPHA1-3)MAN | PORE-FORMING PROTEIN, AEOLYSIN-LIKE PROTEIN, VETEBRATE, HIGH-MANNOSE GLYCANS, COMPLEX, SUGAR BINDING PROTEIN
4znr:B (ASN246) to (ASP305) CRYSTAL STRUCTURE OF DLN1 COMPLEXED WITH MAN(ALPHA1-3)MAN | PORE-FORMING PROTEIN, AEOLYSIN-LIKE PROTEIN, VETEBRATE, HIGH-MANNOSE GLYCANS, COMPLEX, SUGAR BINDING PROTEIN
4l6x:A (VAL455) to (ASP494) CRYSTAL STRUCTURE OF A GH48 CELLOBIOHYDROLASE FROM CALDICELLULOSIRUPTOR BESCII | CELLOBIOHYDROLASE, PROCESSIVE, HYDROLASE, SUGAR BINDING PROTEIN
4l7g:A (TYR342) to (ALA368) DIETHYLAMINOSULFUR TRIFLUORIDE-MEDIATED INTRAMOLECULAR CYCLIZATION OF 2-HYDROXY-BENZYLUREAS TO FUSED BICYCLIC AMINOOXAZOLINE COMPOUNDS AND EVALUATION OF THEIR BIOCHEMICAL ACTIVITY AGAINST BETA-SECRETASE-1 (BACE1) | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4l7j:A (TYR342) to (ALA368) DIETHYLAMINOSULFUR TRIFLUORIDE-MEDIATED INTRAMOLECULAR CYCLIZATION OF 2-HYDROXY-BENZYLUREAS TO FUSED BICYCLIC AMINOOXAZOLINE COMPOUNDS AND EVALUATION OF THEIR BIOCHEMICAL ACTIVITY AGAINST BETA-SECRETASE-1 (BACE-1) | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4l99:A (ALA287) to (ALA332) STRUCTURE OF THE RBP FROM LACTOCOCCAL PHAGE 1358 IN COMPLEX WITH GLYCEROL | BETA SANDWICH DOMAIN, PHAGE RECEPTOR BINDING PROTEIN, LACTOCOCCUS LACTIS PELLICLE SURFACE SACCHARIDE, VIRAL PROTEIN
2w41:A (ALA262) to (ILE309) CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM GLYCEROL KINASE WITH ADP | CLOSED CONFORMATION, KINASE, MALARIA, PLASMODIUM, TRANSFERASE, SUGAR KINASE/HSP70/ACTIN SUPERFAMILY, GLYCEROL KINASE, OPEN CONFORMATION
4zsp:B (ASN5) to (THR33) BACE CRYSTAL STRUCTURE WITH BICYCLIC AMINOTHIAZINE INHIBITOR | ASPARTYL, PROTEASE, BETA-SECRETASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ine:A (ASN67) to (THR95) BACE1 WITH THE AMINOHYDANTOIN COMPOUND S-34 | BACE1, XRAY, INHIBITOR, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
4lgh:A (GLY284) to (GLU339) CRYSTAL STRUCTURE OF 1NM-PP1 BOUND TO ANALOG-SENSITIVE SRC KINASE | KINASE DOMAIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ipv:B (ARG75) to (THR129) CRYSTAL STRUCTURE OF SPATHOLOBUS PARVIFLORUS SEED LECTIN | GALACTOSE BINDING, SEED LECTIN, HEMAGGLUTININ, LEGUME LECTIN, ANTI FUNGAL, SUGAR BINDING PROTEIN
2w8b:D (VAL283) to (ASP307) CRYSTAL STRUCTURE OF PROCESSED TOLB IN COMPLEX WITH PAL | PROTEIN TRANSPORT MEMBRANE PROTEIN COMPLEX, TOL, PAL, TOLB, MEMBRANE, PALMITATE, PERIPLASM, BACTERIOCIN TRANSPORT, TRANSPORT PROTEIN/LIPOPROTEIN, CELL OUTER MEMBRANE, TRANSPORT, LIPOPROTEIN, CELL MEMBRANE, OUTER MEMBRANE
4lhk:A (THR110) to (GLY141) STRUCTURE OF THE N-TERMINAL DOMAIN OF THE LG-FLO1 ADHESIN (N-LG-FLO1P) FROM THE YEAST SACCHAROMYCES PASTORIANUS, IN COMPLEX WITH CALCIUM AND ALPHA-1,2-MANNOBIOSE | PA14 DOMAIN, CELL ADHESION
2w9p:M (ASN42) to (LYS76) CRYSTAL STRUCTURE OF POTATO MULTICYSTATIN | PROTEASE INHIBITOR, THIOL PROTEASE INHIBITOR, HYDROLASE INHIBITOR
2hb0:A (GLY227) to (LEU284) CRYSTAL STRUCTURE OF CFAE, THE ADHESIVE SUBUNIT OF CFA/I FIMBRIA OF ENTEROTOXIGENIC ESCHERICHIA COLI | CFAE, ADHESIN, ETEC, CFA/I, TRAVELER'S DISEASE, CELL ADHESION
3iw7:A (THR7) to (LEU55) HUMAN P38 MAP KINASE IN COMPLEX WITH AN IMIDAZO-PYRIDINE | DFG-OUT, TYPE-I, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
2hiz:B (ASN5) to (ASN28) CRYSTAL STRUCTURE OF HUMAN BETA-SECRETASE (BACE) IN THE PRESENCE OF AN INHIBITOR | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
4lmk:A (VAL154) to (TYR193) GLIC LIGANDED-CLOSED-CHANNEL CONFORMATION, MUTANT Y27'A | PENTAMERIC LIGAND-GATED ION CHANNEL, MEMBRANE PROTEIN, PROKARYOTIC CYS-LOOP RECEPTOR, TRANSPORT PROTEIN
4lmk:B (VAL154) to (TYR193) GLIC LIGANDED-CLOSED-CHANNEL CONFORMATION, MUTANT Y27'A | PENTAMERIC LIGAND-GATED ION CHANNEL, MEMBRANE PROTEIN, PROKARYOTIC CYS-LOOP RECEPTOR, TRANSPORT PROTEIN
2wj0:B (ALA81) to (ASP110) CRYSTAL STRUCTURES OF HOLLIDAY JUNCTION RESOLVASES FROM ARCHAEOGLOBUS FULGIDUS BOUND TO DNA SUBSTRATE | HYDROLASE DNA COMPLEX, TYPE II RESTRICTION ENDONUCLEASE, HOLLIDAY JUNCTION RESOLVASE, HYDROLASE, DNA BINDING PROTEIN
3vv6:A (TYR342) to (ALA368) CRYSTAL STRUCTURE OF BETA SECETASE IN COMPLEX WITH 2-AMINO-3-METHYL-6- ((1S, 2R)-2-PHENYLCYCLOPROPYL)PYRIMIDIN-4(3H)-ONE | ASPARTYL PROTEASE, BACE, BATA SECRETASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4lqe:A (GLU31) to (PRO97) CRYSTAL STRUCTURE OF MEPB | ENDONUCLEASE, DNA BINDING PROTEIN
2wmp:B (PHE253) to (LEU293) STRUCTURE OF THE E. COLI CHAPERONE PAPD IN COMPLEX WITH THE PILIN DOMAIN OF THE PAPGII ADHESIN | CHAPERONE, CELL ADHESION, DONOR STRAND COMPLEMENTATION, PILIN DOMAIN, IMMUNOGLOBULIN DOMAIN, BACTERIAL ATTACHMENT AND INVASION, DONOR STRAND EXCHANGE, CHAPERONE USHER PATHWAY
3w1e:A (ASN53) to (TYR86) STRUCTURE OF FLGT, A FLAGELLAR BASAL BODY COMPONENT PROTEIN | H-RING FORMATION, THE FLAGELLAR BASAL BODY, MOTOR PROTEIN
2hv2:A (THR44) to (TYR84) CRYSTAL STRUCTURE OF CONSERVED PROTEIN OF UNKNOWN FUNCTION FROM ENTEROCOCCUS FAECALIS V583 AT 2.4 A RESOLUTION, PROBABLE N- ACYLTRANSFERASE | PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
2hv2:C (THR44) to (TYR84) CRYSTAL STRUCTURE OF CONSERVED PROTEIN OF UNKNOWN FUNCTION FROM ENTEROCOCCUS FAECALIS V583 AT 2.4 A RESOLUTION, PROBABLE N- ACYLTRANSFERASE | PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
2hv2:F (GLN45) to (GLY79) CRYSTAL STRUCTURE OF CONSERVED PROTEIN OF UNKNOWN FUNCTION FROM ENTEROCOCCUS FAECALIS V583 AT 2.4 A RESOLUTION, PROBABLE N- ACYLTRANSFERASE | PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
3izg:G (GLU110) to (LYS151) BACTERIOPHAGE T7 PROHEAD SHELL EM-DERIVED ATOMIC MODEL | BACTERIOPHAGE, VIRUS, CAPSID MATURATION, CRYOELECTRON MICROSCOPY, MORPHOGENETIC INTERMEDIATE, ICOSAHEDRAL
3izg:B (GLU110) to (LYS151) BACTERIOPHAGE T7 PROHEAD SHELL EM-DERIVED ATOMIC MODEL | BACTERIOPHAGE, VIRUS, CAPSID MATURATION, CRYOELECTRON MICROSCOPY, MORPHOGENETIC INTERMEDIATE, ICOSAHEDRAL
3izg:E (GLU110) to (LYS151) BACTERIOPHAGE T7 PROHEAD SHELL EM-DERIVED ATOMIC MODEL | BACTERIOPHAGE, VIRUS, CAPSID MATURATION, CRYOELECTRON MICROSCOPY, MORPHOGENETIC INTERMEDIATE, ICOSAHEDRAL
1u8e:A (PRO181) to (ASP230) HUMAN DIPEPTIDYL PEPTIDASE IV/CD26 MUTANT Y547F | ALPHA/BETA HYDROLASE, BETA-PROPELLER, HOMODIMER, HYDROLASE
2hwp:B (GLY279) to (GLU339) CRYSTAL STRUCTURE OF SRC KINASE DOMAIN IN COMPLEX WITH COVALENT INHIBITOR PD168393 | KINASE, COVALENT, QUINAZOLINE, MODIFICATION, TRANSFERASE
2hzm:G (GLU128) to (ALA157) STRUCTURE OF THE MEDIATOR HEAD SUBCOMPLEX MED18/20 | BETA BARREL, CHANNEL, TRANSCRIPTION
2i00:D (LYS61) to (TYR100) CRYSTAL STRUCTURE OF ACETYLTRANSFERASE (GNAT FAMILY) FROM ENTEROCOCCUS FAECALIS | ACETYLTRANSFERASE, GNAT FAMILY, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, TRANSFERASE
2i00:F (SER60) to (TYR100) CRYSTAL STRUCTURE OF ACETYLTRANSFERASE (GNAT FAMILY) FROM ENTEROCOCCUS FAECALIS | ACETYLTRANSFERASE, GNAT FAMILY, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, TRANSFERASE
1ue1:B (ASP16) to (TRP60) CRYSTAL STRUCTURE OF THE SINGLE-STRANDED DNA-BINDING PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS | OLIGONUCLEOTIDE BINDING FOLD, DNA-BINDING PROTEIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, DNA BINDING PROTEIN
1ue7:A (ASP16) to (ARG61) CRYSTAL STRUCTURE OF THE SINGLE-STRANDED DNA-BINDING PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS | OLIGONUCLEOTIDE BINDING FOLD, DNA-BINDING PROTEIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, DNA BINDING PROTEIN
2wuh:A (PRO157) to (GLY184) CRYSTAL STRUCTURE OF THE DDR2 DISCOIDIN DOMAIN BOUND TO A TRIPLE-HELICAL COLLAGEN PEPTIDE | RECEPTOR-PEPTIDE COMPLEX, TRANSFERASE, NUCLEOTIDE-BINDING, TYROSINE-PROTEIN KINASE
1ufg:A (HIS33) to (ASN56) SOLUTION STRUCTURE OF IMMUNOGLOBULIN LIKE DOMAIN OF MOUSE NUCLEAR LAMIN | IMMUNOGLOBULIN LIKE FOLD, NUCLEAR LAMIN, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL PROTEIN
1ifg:A (ILE115) to (ASN138) CRYSTAL STRUCTURE OF A MONOMERIC FORM OF GENERAL PROTEASE INHIBITOR, ECOTIN IN ABSENCE OF A PROTEASE | MONOMERIC ECOTIN, SERINE PROTEASE INHIBITOR, HYDROLASE INHIBITOR
4m1x:A (ASP31) to (HIS53) TETRAMERIC RING STRUCTURE OF 201PHI2-1P060 FROM PSEUDOMONAS PHAGE 201PHI2-1 | TETRAMER, RING, FERREDOXIN-LIKE FOLD, UNKNOWN FUNCTION
4m1x:D (ASP31) to (HIS53) TETRAMERIC RING STRUCTURE OF 201PHI2-1P060 FROM PSEUDOMONAS PHAGE 201PHI2-1 | TETRAMER, RING, FERREDOXIN-LIKE FOLD, UNKNOWN FUNCTION
2i4e:A (ASP1821) to (GLY1850) STRUCTURAL STUDIES OF PROTEIN TYROSINE PHOSPHATASE BETA CATALYTIC DOMAIN IN COMPLEX WITH INHIBITORS | PROTEIN TYROSINE PHOSPHATASE, WPD-LOOP, SULFAMIC ACID, PHOSPHATASE, INHIBITOR, DRUG DESIGN, HYDROLASE
3j07:A (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:B (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:C (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:D (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:E (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:F (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:G (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:H (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:I (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:J (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:K (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:L (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:M (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:N (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:O (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:P (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:Q (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:R (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:S (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:T (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:U (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:V (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:W (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j07:X (GLU88) to (ARG123) MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER | SHSP, CHAPERONE
3j0c:B (VAL82) to (ALA102) MODELS OF E1, E2 AND CP OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS TC-83 STRAIN RESTRAINED BY A NEAR ATOMIC RESOLUTION CRYO-EM MAP | ALPHAVIRUS, BIOWEAPON, VIRUS
3j0c:E (VAL82) to (ALA102) MODELS OF E1, E2 AND CP OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS TC-83 STRAIN RESTRAINED BY A NEAR ATOMIC RESOLUTION CRYO-EM MAP | ALPHAVIRUS, BIOWEAPON, VIRUS
3j0c:K (VAL82) to (ALA102) MODELS OF E1, E2 AND CP OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS TC-83 STRAIN RESTRAINED BY A NEAR ATOMIC RESOLUTION CRYO-EM MAP | ALPHAVIRUS, BIOWEAPON, VIRUS
1inp:A (VAL184) to (TYR225) CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 1-PHOSPHATASE AT 2.3 ANGSTROMS RESOLUTION | HYDROLASE(PHOSPHORIC MONOESTER)
4m4d:B (VAL218) to (LYS248) CRYSTAL STRUCTURE OF LIPOPOLYSACCHARIDE BINDING PROTEIN | BETA BARREL, IMMUNE RESPONSE, LIPOPOLYSACCHARIDE, BLOOD, LIPID BINDING PROTEIN
2ww8:A (SER166) to (ARG192) STRUCTURE OF THE PILUS ADHESIN (RRGA) FROM STREPTOCOCCUS PNEUMONIAE | IGG, PILUS, CNA_B, ADHESIN, INTEGRIN, CELL ADHESION
4m4r:A (ASN334) to (ALA371) EPHA4 ECTODOMAIN COMPLEX WITH EPHRIN A5 | EPH RECEPTOR EPHRIN COMPLEX, TRANSFERASE
4m4r:B (TYR48) to (MET81) EPHA4 ECTODOMAIN COMPLEX WITH EPHRIN A5 | EPH RECEPTOR EPHRIN COMPLEX, TRANSFERASE
1umg:A (ALA256) to (PHE311) CRYSTAL STRUCURE OF FRUCTOSE-1,6-BISPHOSPHATASE | FRUCTOSE-1,6-BISPHOSPHATASE, HYPERTHERMOPHILIC ARCHAEA, ALPHA-BETA- BETA-ALPHA FOUR LAYER SANDWICH, MAGNESIUM ION, PHOSPHATASE, OCTAMER, THREE METAL-ASSISTED MECHANISM, HYDROLASE
2ich:B (GLN314) to (GLY349) CRYSTAL STRUCTURE OF A PUTATIVE ATTH (NE1406) FROM NITROSOMONAS EUROPAEA AT 2.00 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LIPID BINDING PROTEIN
2wyb:B (ARG89) to (ARG118) THE QUORUM QUENCHING N-ACYL HOMOSERINE LACTONE ACYLASE PVDQ WITH A COVALENTLY BOUND DODECANOIC ACID | ZYMOGEN, HYDROLASE, PERIPLASM
3wat:B (ILE242) to (ASN277) CRYSTAL STRUCTURE OF 4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE MGP COMPLEXED WITH MAN+GLC | 5-BLADED BETA PROPELLER FOLD, PHOSPHORYLASE, MANNAN BIODEGRADATION, TRANSFERASE
2wyl:B (ASP168) to (THR216) APO STRUCTURE OF A METALLO-B-LACTAMASE | HYDROLASE
2wyl:F (ASP168) to (THR216) APO STRUCTURE OF A METALLO-B-LACTAMASE | HYDROLASE
2iff:H (TYR178) to (LYS212) STRUCTURE OF AN ANTIBODY-LYSOZYME COMPLEX: EFFECT OF A CONSERVATIVE MUTATION | IMMUNOGLOBULIN/HYDROLASE(O-GLYCOSYL), IMMUNOGLOBULIN-HYDROLASE(O- GLYCOSYL) COMPLEX
4mbo:A (SER471) to (ASN503) 1.65 ANGSTROM CRYSTAL STRUCTURE OF SERINE-RICH REPEAT ADHESION GLYCOPROTEIN (SRR1) FROM STREPTOCOCCUS AGALACTIAE | CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, STRUCTURAL GENOMICS, SERINE-RICH REPEAT, SRR1, FIBRINOGEN BINDING GLYCOPROTEIN, PROTEIN BINDING
4mbr:A (PRO382) to (ASN414) 3.65 ANGSTROM CRYSTAL STRUCTURE OF SERINE-RICH REPEAT PROTEIN (SRR2) FROM STREPTOCOCCUS AGALACTIAE | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, SERINE-RICH REPEAT PROTEIN, SRR2, FIBRINOGEN BINDING GLYCOPROTEIN, PROTEIN BINDING
2igt:C (GLY32) to (LYS84) CRYSTAL STRUCTURE OF THE SAM DEPENDENT METHYLTRANSFERASE FROM AGROBACTERIUM TUMEFACIENS | ALPHA-BETA SANDWICH, BETA-BARREL, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, TRANSFERASE
1uun:A (ASN4) to (GLY44) MAIN PORIN FROM MYCOBACTERIA SMEGMATIS (MSPA) | PORIN, MYCOBACTERIA
1uun:B (ASN4) to (GLY44) MAIN PORIN FROM MYCOBACTERIA SMEGMATIS (MSPA) | PORIN, MYCOBACTERIA
3wea:A (CYS6) to (VAL46) CRYSTAL STRUCTURE OF A NIEMANN-PICK TYPE C2 PROTEIN FROM JAPANESE CARPENTER ANT | IMMUNOGLOBULIN-LIKE BETA-SANDWICH FOLD, CARRIER PROTEIN, LIPID BINDING PROTEIN
2x12:B (GLN251) to (PRO288) PH-INDUCED MODULATION OF STREPTOCOCCUS PARASANGUINIS ADHESION BY FAP1 FIMBRIAE | BIOFILM, CELL WALL, CELL ADHESION, PEPTIDOGLYCAN-ANCHOR
1iyk:B (HIS138) to (HIS180) CRYSTAL STRUCTURE OF CANDIDA ALBICANS N-MYRISTOYLTRANSFERASE WITH MYRISTOYL-COA AND PEPTIDIC INHIBITOR | TRANSFERASE
5afk:C (GLN157) to (LYS202) ALPHA7-ACHBP IN COMPLEX WITH LOBELINE AND FRAGMENT 2 | TRANSPORT PROTEIN, PENTAMERIC LIGAND-GATED ION CHANNELS, CYS-LOOP RECEPTOR, NICOTINIC ACETYLCHOLINE RECEPTOR, ALLOSTERIC MODULATION, DRUG DISCOVERY
5afl:D (GLN157) to (LYS202) ALPHA7-ACHBP IN COMPLEX WITH LOBELINE AND FRAGMENT 3 | TRANSPORT PROTEIN, PENTAMERIC LIGAND-GATED ION CHANNELS, CYS-LOOP RECEPTOR, NICOTINIC ACETYLCHOLINE RECEPTOR, ALLOSTERIC MODULATION, DRUG DISCOVERY
5afm:A (GLN157) to (LYS202) ALPHA7-ACHBP IN COMPLEX WITH LOBELINE AND FRAGMENT 4 | TRANSPORT PROTEIN, PENTAMERIC LIGAND-GATED ION CHANNELS, CYS-LOOP RECEPTOR, NICOTINIC ACETYLCHOLINE RECEPTOR, ALLOSTERIC MODULATION, DRUG DISCOVERY
5afm:D (GLN157) to (LYS202) ALPHA7-ACHBP IN COMPLEX WITH LOBELINE AND FRAGMENT 4 | TRANSPORT PROTEIN, PENTAMERIC LIGAND-GATED ION CHANNELS, CYS-LOOP RECEPTOR, NICOTINIC ACETYLCHOLINE RECEPTOR, ALLOSTERIC MODULATION, DRUG DISCOVERY
1j4k:A (THR668) to (ILE696) SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53 COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE DERIVED FROM RAD9 | FHA DOMAIN, RAD53, RAD9, PHOSPHOTYROSINE, PHOSPHOPROTEIN, TRANSFERASE
1j4l:A (THR668) to (ILE696) SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53 COMPLEXED WITH A PHOSPHOTHREONYL PEPTIDE DERIVED FROM RAD9 | FHA DOMAIN, RAD53, RAD9, PHOSPHOTHREONINE, PHOSPHOPROTEIN, TRANSFERASE
2x6w:A (LEU663) to (GLU692) TAILSPIKE PROTEIN MUTANT E372Q OF E.COLI BACTERIOPHAGE HK620 IN COMPLEX WITH HEXASACCHARIDE | VIRAL PROTEIN, BETA-HELIX, HYDROLASE
2x6y:A (LEU663) to (GLU692) TAILSPIKE PROTEIN MUTANT D339A OF E.COLI BACTERIOPHAGE HK620 IN COMPLEX WITH HEXASACCHARIDE | VIRAL PROTEIN, RIGHT-HANDED PARALLEL BETA-HELIX, VIRAL ADHESION PROTEIN, ENDO-N-ACETYLGLUCOSAMINIDASE, HYDROLASE
5akc:B (THR462) to (PRO504) MUTS IN COMPLEX WITH THE N-TERMINAL DOMAIN OF MUTL - CRYSTAL FORM 2 | HYDROLASE, DNA MISMATCH REPAIR, COMPLEX, SLIDING CLAMP, CROSSLINKING
2ius:F (ASN883) to (PRO939) E. COLI FTSK MOTOR DOMAIN | NUCLEOTIDE-BINDING, CHROMOSOME PARTITION, ATP-BINDING, DNA- BINDING, CELL DIVISION, TRANSMEMBRANE, INNER MEMBRANE, HEXAMERIC RING, DNA TRANSLOCATION, KOPS, MEMBRANE, DIVISOME, CELL CYCLE, AAA ATPASE, MEMBRANE PROTEIN
1v8j:A (LYS90) to (ASP126) THE CRYSTAL STRUCTURE OF THE MINIMAL FUNCTIONAL DOMAIN OF THE MICROTUBULE DESTABILIZER KIF2C COMPLEXED WITH MG-ADP | KINESIN-LIKE PROTEIN, MICROTUBULE DESTABILIZER, STRUCTURAL PROTEIN
1v8k:A (LYS90) to (ASP126) THE CRYSTAL STRUCTURE OF THE MINIMAL FUNCTIONAL DOMAIN OF THE MICROTUBULE DESTABILIZER KIF2C COMPLEXED WITH MG-AMPPNP | KINESIN-LIKE PROTEIN, MICROTUBULE DESTABILIZER, STRUCTURAL PROTEIN
3wo3:K (LYS112) to (ILE137) CRYSTAL STRUCTURE OF IL-18 IN COMPLEX WITH IL-18 RECEPTOR ALPHA | BINARY COMPLEX, BETA TREFOIL FOLD (LIGAND), THREE IMMUNOGLOBULIN-LIKE DOMAINS (RECEPTOR), IMMUNITY, INFLAMMATION, AUTOIMMUNITY, ALLERGY, INTERLEUKIN-18 RECEPTOR BETA, GLYCOSYLATION, SERUM, MEMBRANE, IMMUNE SYSTEM
5ams:B (VAL404) to (GLU428) CRYSTAL STRUCTURE OF SQT1 | CHAPERONE, SQT1, RIBOSOME, UL16
2ixq:B (ILE25) to (PRO71) THE SOLUTION STRUCTURE OF THE INVASIVE TIP COMPLEX FROM AFA-DR FIBRILS | IG-LIKE DOMAIN, AFIMBRIAL SHEATH, STRUCTURAL PROTEIN, DONOR STRAND COMPLEMENTED, CELL ADHESION, DAF, AFAE, UPEC, DAEC, FIMBRIA
5anh:A (PRO395) to (TYR416) CRYSTAL STRUCTURE OF LACCASE FROM BASIDIOMYCETE PM1 (CECT 2971) | LACCASE, OXIDOREDUCTASE, LIGNIN DEGRADATION
3wpu:B (ASP217) to (GLY254) FULL-LENGTH BETA-FRUCTOFURANOSIDASE FROM MICROBACTERIUM SACCHAROPHILUM K-1 | GLYCOSIDE HYDROLASE FAMILY 68, BETA-PROPELLER, HYDROLASE
5aot:A (TRP490) to (HIS511) VERY HIGH RESOLUTION STRUCTURE OF A NOVEL CARBOHYDRATE BINDING MODULE FROM RUMINOCOCCUS FLAVEFACIENS FD-1 ENDOGLUCANASE CEL5A | SUGAR BINDING PROTEN, CARBOHYDRATE BINDING MODULE, ENDOGLUCANASE CEL5A, CELLULOSOME, RUMINOCOCCUS FLAVEFACIENS FD-1, CARBOHYDRATE ACTIVE ENZYME
1jkf:A (VAL344) to (CYS436) HOLO 1L-MYO-INOSITOL-1-PHOSPHATE SYNTHASE | ROSSMANN FOLD, ISOMERASE
2j5f:A (LEU718) to (LEU747) CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN IN COMPLEX WITH AN IRREVERSIBLE INHIBITOR 34-JAB | CELL CYCLE, ATP-BINDING, TRANSFERASE, POLYMORPHISM, IRREVERSIBLE INHIBITOR, TYROSINE-PROTEIN KINASE, EGFR, KINASE, 34-JAB, MEMBRANE, RECEPTOR, WILD-TYPE, EPIDERMAL GROWTH FACTOR, ANTI-ONCOGENE, TRANSMEMBRANE, NUCLEOTIDE- BINDING, ALTERNATIVE SPLICING, UBL CONJUGATION, PHOSPHORYLATION, DISEASE MUTATION, GLYCOPROTEIN
2xhn:A (ASN192) to (SER229) RHAMNOGALACTURONAN LYASE FROM ASPERGILLUS ACULEATUS K150A ACTIVE SITE MUTANT | CARBOHYDRATE ACTIVE ENZYME, LYASE, PECTIN, DEGRADATION, POLYSACCHARIDE LYASE FAMILY 4
2xhn:B (ASN192) to (SER229) RHAMNOGALACTURONAN LYASE FROM ASPERGILLUS ACULEATUS K150A ACTIVE SITE MUTANT | CARBOHYDRATE ACTIVE ENZYME, LYASE, PECTIN, DEGRADATION, POLYSACCHARIDE LYASE FAMILY 4
1vpz:A (GLU10) to (ALA36) CRYSTAL STRUCTURE OF A PUTATIVE CARBON STORAGE REGULATOR PROTEIN (CSRA, PA0905) FROM PSEUDOMONAS AERUGINOSA AT 2.05 A RESOLUTION | CSRA-LIKE FOLD, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI, RNA BINDING PROTEIN
1vpz:B (GLU10) to (ALA36) CRYSTAL STRUCTURE OF A PUTATIVE CARBON STORAGE REGULATOR PROTEIN (CSRA, PA0905) FROM PSEUDOMONAS AERUGINOSA AT 2.05 A RESOLUTION | CSRA-LIKE FOLD, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI, RNA BINDING PROTEIN
1vqa:A (ALA11) to (GLU51) GENE V PROTEIN MUTANT WITH VAL 35 REPLACED BY ALA 35 AND ILE 47 REPLACED BY LEU 47 (V35A, I47L) | DNA-BINDING PROTEIN, MUTANT, GENE V
1vqe:A (ALA11) to (GLU51) GENE V PROTEIN MUTANT WITH VAL 35 REPLACED BY ILE 35 AND ILE 47 REPLACED BY MET 47 (V35I, I47M) | DNA-BINDING PROTEIN, GENE V, MUTANT
1vqf:A (ALA11) to (GLU51) GENE V PROTEIN MUTANT WITH VAL 35 REPLACED BY ILE 35 AND ILE 47 REPLACED BY VAL 47 (V35I, I47V) | DNA-BINDING PROTEIN, GENE V, MUTANT
1vqh:A (ALA11) to (GLU51) GENE V PROTEIN MUTANT WITH ILE 47 REPLACED BY MET 47 (I47M) | DNA-BINDING PROTEIN, GENE V, MUTANT
1vqj:A (ALA11) to (GLU51) GENE V PROTEIN MUTANT WITH VAL 35 REPLACED BY ILE 35 (V35I) | DNA-BINDING PROTEIN, MUTANT, GENE V, BACTERIOPHAGE
3wxg:A (HIS801) to (GLU841) CRYSTAL STRUCTURE OF CYLD USP DOMAIN (C596A) IN COMPLEX WITH LYS63- LINKED DIUBIQUITIN | UBIQUITIN PROTEASE, HYDROLASE-PROTEIN BINDING COMPLEX
3wxg:D (HIS801) to (GLU841) CRYSTAL STRUCTURE OF CYLD USP DOMAIN (C596A) IN COMPLEX WITH LYS63- LINKED DIUBIQUITIN | UBIQUITIN PROTEASE, HYDROLASE-PROTEIN BINDING COMPLEX
3wxi:A (GLU269) to (ALA316) CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI GAMBIENSE GLYCEROL KINASE (LIGAND-FREE FORM) | GLYCEROL KINASE, TRYPANOSOMA, SUGAR KINASE SUPERFAMILY, TRANSFERASE, GLYCOSOME
3wxj:A (ALA270) to (ALA318) CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI GAMBIENSE GLYCEROL KINASE IN COMPLEX WITH GLYCEROL 3-PHOSPHATE | TRYPANOSOMA, GLYCEROL KINASE, SUGAR KINASE SUPERFAMILY, TRANSFERASE, GLYCOSOME
3wxj:D (GLU269) to (ALA318) CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI GAMBIENSE GLYCEROL KINASE IN COMPLEX WITH GLYCEROL 3-PHOSPHATE | TRYPANOSOMA, GLYCEROL KINASE, SUGAR KINASE SUPERFAMILY, TRANSFERASE, GLYCOSOME
4my3:D (ARG49) to (ALA88) CRYSTAL STRUCTURE OF GCN5-RELATED N-ACETYLTRANSFERASE FROM KRIBBELLA FLAVIDA | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, ALPHA-BETA STRUCTURE, TRANSFERASE
4myg:B (VAL31) to (LEU56) MAPK13, ACTIVE FORM | P38 KINASE, PHOSPHORYLATION, TRANSFERASE
5az4:B (LEU627) to (VAL662) CRYSTAL STRUCTURE OF A 79KDA FRAGMENT OF FLGE, THE HOOK PROTEIN FROM CAMPYLOBACTER JEJUNI | FLAGELLUM, HOOK, UNIVERSAL JOINT, MOTOR PROTEIN
4mz9:A (GLU19) to (GLY61) REVISED STRUCTURE OF E. COLI SSB | SINGLE STRAND DNA-BINDING DOMAIN, SSB, RECO, EXOI, RECQ, DNAG, HOLC, DNA BINDING PROTEIN
4mz9:D (ASP17) to (PHE60) REVISED STRUCTURE OF E. COLI SSB | SINGLE STRAND DNA-BINDING DOMAIN, SSB, RECO, EXOI, RECQ, DNAG, HOLC, DNA BINDING PROTEIN
1w0o:A (ILE602) to (PHE638) VIBRIO CHOLERAE SIALIDASE | VIBRIO CHOLERAE, SIALIDASE, GLYCOSIDASE, HYDROLASE
1w0p:A (ILE602) to (PHE638) VIBRIO CHOLERAE SIALIDASE WITH ALPHA-2,6-SIALYLLACTOSE | HYDROLASE, VIBRIO CHOLERAE, SIALIDASE, NEURAMINIDASE, LECTIN
3wz4:H (ALA143) to (ARG187) STRUCTURE OF THE PERIPLASMIC DOMAIN OF DOTI (CRYSTAL FORM I) | TYPE IVB SECRETION, UNKNOWN FUNCTION
5azi:B (GLU269) to (ALA318) CRYSTAL STRUCTURE OF GLYCEROL KINASE FROM TRYPANOSOMA BRUCEI GAMBIENSE COMPLEXED WITH 4NP | GLYCEROL KINASE, PHOSPHATASE, 4NP, AFRICAN TRYPANOSOMES, TRANSFERASE
5azi:D (GLU269) to (ALA318) CRYSTAL STRUCTURE OF GLYCEROL KINASE FROM TRYPANOSOMA BRUCEI GAMBIENSE COMPLEXED WITH 4NP | GLYCEROL KINASE, PHOSPHATASE, 4NP, AFRICAN TRYPANOSOMES, TRANSFERASE
5azj:B (GLU269) to (ALA316) CRYSTAL STRUCTURE OF GLYCEROL KINASE FROM TRYPANOSOMA BRUCEI GAMBIENSE COMPLEXED WITH 4NP (WITH DISULFIDE BRIDGE) | GLYCEROL KINASE, PHOSPHATASE, 4NP, AFRICAN TRYPANOSOMES, TRANSFERASE
5azj:D (GLU269) to (ALA316) CRYSTAL STRUCTURE OF GLYCEROL KINASE FROM TRYPANOSOMA BRUCEI GAMBIENSE COMPLEXED WITH 4NP (WITH DISULFIDE BRIDGE) | GLYCEROL KINASE, PHOSPHATASE, 4NP, AFRICAN TRYPANOSOMES, TRANSFERASE
3x2x:C (GLY92) to (GLU132) CRYSTAL STRUCTURE OF METALLO-BETA-LACTAMASE H48A FROM THERMOTOGA MARITIMA | HYDROLASE
3x2z:C (GLY92) to (ILE131) CRYSTAL STRUCTURE OF METALLO-BETA-LACTAMASE IN COMPLEX WITH NICKEL FROM THERMOTOGA MARITIMA | HYDROLASE
2jgu:A (ILE54) to (LEU87) CRYSTAL STRUCTURE OF DNA-DIRECTED DNA POLYMERASE | DNA-DIRECTED DNA POLYMERASE, PFU, NUCLEASE, HYDROLASE, TRANSFERASE, DNA-BINDING, ENDONUCLEASE, DNA REPLICATION, NUCLEOTIDYLTRANSFERASE
3zef:B (PRO1256) to (VAL1304) CRYSTAL STRUCTURE OF PRP8:AAR2 COMPLEX: SECOND CRYSTAL FORM AT 3.1 ANGSTROM RESOLUTION | TRANSLATION, PRE-MRNA SPLICING, SPLICEOSOME, U5 SNRNP
3zef:E (PRO1256) to (VAL1304) CRYSTAL STRUCTURE OF PRP8:AAR2 COMPLEX: SECOND CRYSTAL FORM AT 3.1 ANGSTROM RESOLUTION | TRANSLATION, PRE-MRNA SPLICING, SPLICEOSOME, U5 SNRNP
5boh:A (VAL209) to (TYR234) CRYSTAL STRUCTURE OF OXA-58 WITH THE SUBSTRATE-BINDING CLEFT IN A CLOSED STATE | BETA-LACTAMASE, CARBAPENEM, MULTI-DRUG RESISTANCE, CARBAMIC ACID, HYDROLASE
1w84:A (THR7) to (LEU55) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH SMALL MOLECULE INHIBITOR | KINASE/INHIBITOR, KINASE/INHIBITOR COMPLEX, P38, KINASE, INHIBITOR COMPLEX
2jhu:B (PHE102) to (ARG134) CRYSTAL STRUCTURE OF RHOGDI E154A,E155A MUTANT | SURFACE ENTROPY REDUCTION, INHIBITOR, GTPASE ACTIVATION, CRYSTAL ENGINEERING
2jhw:A (PHE102) to (ARG134) CRYSTAL STRUCTURE OF RHOGDI E155A, E157A MUTANT | SURFACE ENTROPY REDUCTION, INHIBITOR, GTPASE ACTIVATION, CRYSTAL ENGINEERING
2jhw:B (GLN100) to (ARG134) CRYSTAL STRUCTURE OF RHOGDI E155A, E157A MUTANT | SURFACE ENTROPY REDUCTION, INHIBITOR, GTPASE ACTIVATION, CRYSTAL ENGINEERING
2xvr:C (GLU110) to (ILE165) PHAGE T7 EMPTY MATURE HEAD SHELL | VIRUS, CAPSID MATURATION, MORPHOGENETIC INTERMEDIATE
2jiv:A (LEU718) to (LEU747) CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN T790M MUTATION IN COMPEX WITH HKI-272 | HKI272, HKI-272, RECEPTOR, CELL CYCLE, ATP-BINDING, TRANSFERASE, TYROSINE-PROTEIN KINASE, TRANSMEMBRANE, PHOSPHORYLATION, DISEASE MUTATION, NUCLEOTIDE-BINDING, ANTI-ONCOGENE, EPIDERMAL GROWTH FACTOR
1k2p:B (LEU405) to (LYS433) CRYSTAL STRUCTURE OF BRUTON'S TYROSINE KINASE DOMAIN | BRUTON TRYOSINE KINASE, KINASE DOMAIN, TRANSFERASE
1wbo:A (THR7) to (LEU55) FRAGMENT BASED P38 INHIBITORS | TRANSFERASE, ATP-BINDING, DIRECT PROTEIN SEQUENCING, NUCLEAR PROTEIN, PHOSPHORYLATION, SERINE/THREONINE-PROTEIN KINASE, 38 MAP KINASE, INHIBITOR STRUCTURE
4neh:A (THR657) to (ASN695) AN INTERNAL LIGAND-BOUND, METASTABLE STATE OF A LEUKOCYTE INTEGRIN, AXB2 | ROSSMANN FOLD,, COMPLEMENT RECEPTOR, IC3B, ICAM-1, FIBRINOGEN, DENATURATED PROTEINS, HEPARIN, N-LINKED GLYCOSYLATION, MEMBRANE, CELL ADHESION
1wn7:A (ILE54) to (THR88) CRYSTAL STRUCTURE OF ARCHAEAL FAMILY B DNA POLYMERASE MUTANT | TRANSFERASE
2kjl:A (ARG17) to (GLY51) NMR STRUCTURES OF A DESIGNED CYANOVIRIN-N HOMOLOG LECTIN; LKAMG | CYANOVIRIN-N, CVNH, LECTIN, SUGAR BINDING PROTEIN
1kex:A (LYS125) to (GLY151) CRYSTAL STRUCTURE OF THE B1 DOMAIN OF HUMAN NEUROPILIN-1 | BETA BARREL, JELLY-ROLL, PROTEIN BINDING
1wrn:A (ARG103) to (ASN146) METAL ION DEPENDENCY OF THE ANTITERMINATOR PROTEIN, HUTP, FOR BINDING TO THE TERMINATOR REGION OF HUT MRNA- A STRUCTURAL BASIS | HUTP, RNA BINDING PROTEIN, ANTITERMINATION, L-HISTIDINE, METAL IONS, CONFORMATIONAL CHANGE
5c16:A (ALA98) to (GLY125) MYOTUBULARIN-RELATED PROETIN 1 | MTMR, PHOSPHATASE, HYDROLASE
3jbc:2 (CYS205) to (PRO255) COMPLEX OF POLIOVIRUS WITH VHH PVSP29F | VHH, NANOBODY, POLIOVIRUS, VIRUS-IMMUNE SYSTEM COMPLEX
2l8k:A (ARG91) to (ASP118) NMR STRUCTURE OF THE ARTERIVIRUS NONSTRUCTURAL PROTEIN 7 ALPHA (NSP7 ALPHA) | VIRAL PROTEIN
2lox:A (LYS47) to (ASN92) NMR STRUCTURE OF THE COMPLEX BETWEEN THE PH DOMAIN OF THE TFB1 SUBUNIT FROM TFIIH AND RAD2 | TRANSCRIPTION-HYDROLASE COMPLEX
1kko:A (SER14) to (ALA70) CRYSTAL STRUCTURE OF CITROBACTER AMALONATICUS METHYLASPARTATE AMMONIA LYASE | METHYLASPARTATE AMMONIA LYASE, ENOLASE SUPERFAMILY, TIM BARREL
1kkr:A (SER14) to (ALA70) CRYSTAL STRUCTURE OF CITROBACTER AMALONATICUS METHYLASPARTATE AMMONIA LYASE CONTAINING (2S,3S)-3-METHYLASPARTIC ACID | METHYLASPARTATE AMMONIA LYASE, ENOLASE SUPERFAMILY, TIM BARREL, SUBSTRATE COMPLEX, LYASE
1klf:J (PHE209) to (ASN255) FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE | ADHESIN-CHAPERONE COMPLEX, MANNOSE-BOUND, CHAPERONE/ADHESIN COMPLEX COMPLEX
1klf:N (PHE209) to (ASN255) FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE | ADHESIN-CHAPERONE COMPLEX, MANNOSE-BOUND, CHAPERONE/ADHESIN COMPLEX COMPLEX
1kmt:B (PHE102) to (ARG134) CRYSTAL STRUCTURE OF RHOGDI GLU(154,155)ALA MUTANT | IMMUNOGLOBULIN FOLD, BETA SANDWICH MOTIF, ISOPRENYL-BINDING, PROTEIN BINDING
2mf1:A (GLU10) to (ALA36) STRUCTURAL BASIS OF THE NON-CODING RNA RSMZ ACTING AS PROTEIN SPONGE: CONFORMER R OF RSMZ(1-72)/RSME(DIMER) 1TO3 COMPLEX | PROTEIN/RNA, NON-CODING RNA, TRANSLATION REPRESSOR PROTEIN, PSEUDOMONAS AERUGINOSA, MESSENGER RNA, PROTEIN SEQUESTRATION, TWO CONFORMATIONS, RNASE E CLEAVE SITES, HOMO-DIMERIC PROTEINS, COOPERATIVITY, MULTIPLE PROTEIN BINDING SITES, TRANSLATION ACTIVATION, RIBOSOME BINDING SITE, LARGE SOLUTION STRUCTURE, ELECTRON PARAMAGNETIC RESONANCE, PROTEIN SPONGE, RNP ASSEMBLY, RNA BINDING PROTEIN-RNA COMPLEX
2mf1:C (GLU10) to (ALA36) STRUCTURAL BASIS OF THE NON-CODING RNA RSMZ ACTING AS PROTEIN SPONGE: CONFORMER R OF RSMZ(1-72)/RSME(DIMER) 1TO3 COMPLEX | PROTEIN/RNA, NON-CODING RNA, TRANSLATION REPRESSOR PROTEIN, PSEUDOMONAS AERUGINOSA, MESSENGER RNA, PROTEIN SEQUESTRATION, TWO CONFORMATIONS, RNASE E CLEAVE SITES, HOMO-DIMERIC PROTEINS, COOPERATIVITY, MULTIPLE PROTEIN BINDING SITES, TRANSLATION ACTIVATION, RIBOSOME BINDING SITE, LARGE SOLUTION STRUCTURE, ELECTRON PARAMAGNETIC RESONANCE, PROTEIN SPONGE, RNP ASSEMBLY, RNA BINDING PROTEIN-RNA COMPLEX
2mf1:F (GLU10) to (ALA36) STRUCTURAL BASIS OF THE NON-CODING RNA RSMZ ACTING AS PROTEIN SPONGE: CONFORMER R OF RSMZ(1-72)/RSME(DIMER) 1TO3 COMPLEX | PROTEIN/RNA, NON-CODING RNA, TRANSLATION REPRESSOR PROTEIN, PSEUDOMONAS AERUGINOSA, MESSENGER RNA, PROTEIN SEQUESTRATION, TWO CONFORMATIONS, RNASE E CLEAVE SITES, HOMO-DIMERIC PROTEINS, COOPERATIVITY, MULTIPLE PROTEIN BINDING SITES, TRANSLATION ACTIVATION, RIBOSOME BINDING SITE, LARGE SOLUTION STRUCTURE, ELECTRON PARAMAGNETIC RESONANCE, PROTEIN SPONGE, RNP ASSEMBLY, RNA BINDING PROTEIN-RNA COMPLEX
2ygd:A (LEU89) to (ILE124) MOLECULAR ARCHITECTURES OF THE 24MERIC EYE LENS CHAPERONE ALPHAB-CRYSTALLIN ELUCIDATED BY A TRIPLE HYBRID APPROACH | CHAPERONE, PROTEIN AGGREGATION, HYBRID METHOD
2ygd:C (LEU89) to (ALA126) MOLECULAR ARCHITECTURES OF THE 24MERIC EYE LENS CHAPERONE ALPHAB-CRYSTALLIN ELUCIDATED BY A TRIPLE HYBRID APPROACH | CHAPERONE, PROTEIN AGGREGATION, HYBRID METHOD
2ygd:E (LEU89) to (ILE124) MOLECULAR ARCHITECTURES OF THE 24MERIC EYE LENS CHAPERONE ALPHAB-CRYSTALLIN ELUCIDATED BY A TRIPLE HYBRID APPROACH | CHAPERONE, PROTEIN AGGREGATION, HYBRID METHOD
2ygd:G (LEU89) to (ILE124) MOLECULAR ARCHITECTURES OF THE 24MERIC EYE LENS CHAPERONE ALPHAB-CRYSTALLIN ELUCIDATED BY A TRIPLE HYBRID APPROACH | CHAPERONE, PROTEIN AGGREGATION, HYBRID METHOD
2ygd:I (LEU89) to (ALA126) MOLECULAR ARCHITECTURES OF THE 24MERIC EYE LENS CHAPERONE ALPHAB-CRYSTALLIN ELUCIDATED BY A TRIPLE HYBRID APPROACH | CHAPERONE, PROTEIN AGGREGATION, HYBRID METHOD
2ygd:K (LEU89) to (ILE124) MOLECULAR ARCHITECTURES OF THE 24MERIC EYE LENS CHAPERONE ALPHAB-CRYSTALLIN ELUCIDATED BY A TRIPLE HYBRID APPROACH | CHAPERONE, PROTEIN AGGREGATION, HYBRID METHOD
2ygd:M (LEU89) to (ILE124) MOLECULAR ARCHITECTURES OF THE 24MERIC EYE LENS CHAPERONE ALPHAB-CRYSTALLIN ELUCIDATED BY A TRIPLE HYBRID APPROACH | CHAPERONE, PROTEIN AGGREGATION, HYBRID METHOD
2ygd:O (LEU89) to (ALA126) MOLECULAR ARCHITECTURES OF THE 24MERIC EYE LENS CHAPERONE ALPHAB-CRYSTALLIN ELUCIDATED BY A TRIPLE HYBRID APPROACH | CHAPERONE, PROTEIN AGGREGATION, HYBRID METHOD
2ygd:Q (LEU89) to (ILE124) MOLECULAR ARCHITECTURES OF THE 24MERIC EYE LENS CHAPERONE ALPHAB-CRYSTALLIN ELUCIDATED BY A TRIPLE HYBRID APPROACH | CHAPERONE, PROTEIN AGGREGATION, HYBRID METHOD
2ygd:S (LEU89) to (ILE124) MOLECULAR ARCHITECTURES OF THE 24MERIC EYE LENS CHAPERONE ALPHAB-CRYSTALLIN ELUCIDATED BY A TRIPLE HYBRID APPROACH | CHAPERONE, PROTEIN AGGREGATION, HYBRID METHOD
2ygd:U (LEU89) to (ALA126) MOLECULAR ARCHITECTURES OF THE 24MERIC EYE LENS CHAPERONE ALPHAB-CRYSTALLIN ELUCIDATED BY A TRIPLE HYBRID APPROACH | CHAPERONE, PROTEIN AGGREGATION, HYBRID METHOD
2ygd:W (LEU89) to (ILE124) MOLECULAR ARCHITECTURES OF THE 24MERIC EYE LENS CHAPERONE ALPHAB-CRYSTALLIN ELUCIDATED BY A TRIPLE HYBRID APPROACH | CHAPERONE, PROTEIN AGGREGATION, HYBRID METHOD
2ygp:A (HIS85) to (ASN120) WIF DOMAIN-EGF-LIKE DOMAIN 1 MET77TRP OF HUMAN WNT INHIBITORY FACTOR 1 IN COMPLEX WITH 1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE | SIGNALING PROTEIN, WNT SIGNALING PATHWAY, WNT ANTAGONIST, MORPHOGEN, CANCER, GLYCOSAMINOGLYCAN
1kum:A (VAL567) to (SER592) GLUCOAMYLASE, GRANULAR STARCH-BINDING DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE | HYDROLASE, STARCH BINDING DOMAIN
1kv9:A (ASP233) to (ARG276) STRUCTURE AT 1.9 A RESOLUTION OF A QUINOHEMOPROTEIN ALCOHOL DEHYDROGENASE FROM PSEUDOMONAS PUTIDA HK5 | QUINOHEMOPROTEIN ALCOHOL DEHYDROGENASE, ELECTRON TRANSFER, OXIDOREDUCTASE
1xct:A (SER26) to (TRP56) COMPLEX HCV CORE-FAB 19D9D6-PROTEIN L MUTANT (D55A, L57H, Y64W) IN SPACE GROUP P21212 | CRYSTAL PACKING, FAB, PROTEIN L, PEPTIDE COMPLEX, IMMUNE SYSTEM
2nnz:A (ILE41) to (PHE88) SOLUTION STRUCTURE OF THE HYPOTHETICAL PROTEIN AF2241 FROM ARCHAEOGLOBUS FULGIDUS | BETA-BARREL, STRUCTURAL GENOMICS, ONTARIO CENTRE FOR STRUCTURAL PROTEOMICS, OCSP, UNKNOWN FUNCTION
5cb1:A (SER463) to (VAL493) APO ENZYME OF HUMAN POLYMERASE LAMBDA | POLYMERASE LAMBDA, TRANSFERASE
1l1y:B (ILE477) to (VAL514) THE CRYSTAL STRUCTURE AND CATALYTIC MECHANISM OF CELLOBIOHYDROLASE CELS, THE MAJOR ENZYMATIC COMPONENT OF THE CLOSTRIDIUM THERMOCELLUM CELLULOSOME | ALPHA/ALPHA BARREL, HYDROLASE
1l2a:A (ILE477) to (VAL514) THE CRYSTAL STRUCTURE AND CATALYTIC MECHANISM OF CELLOBIOHYDROLASE CELS, THE MAJOR ENZYMATIC COMPONENT OF THE CLOSTRIDIUM THERMOCELLUM CELLULOSOME | ALPHA/ALPHA BARREL, HYDROLASE
1l2a:B (ILE477) to (VAL514) THE CRYSTAL STRUCTURE AND CATALYTIC MECHANISM OF CELLOBIOHYDROLASE CELS, THE MAJOR ENZYMATIC COMPONENT OF THE CLOSTRIDIUM THERMOCELLUM CELLULOSOME | ALPHA/ALPHA BARREL, HYDROLASE
1l2a:C (ILE477) to (VAL514) THE CRYSTAL STRUCTURE AND CATALYTIC MECHANISM OF CELLOBIOHYDROLASE CELS, THE MAJOR ENZYMATIC COMPONENT OF THE CLOSTRIDIUM THERMOCELLUM CELLULOSOME | ALPHA/ALPHA BARREL, HYDROLASE
1l2a:E (ILE477) to (VAL514) THE CRYSTAL STRUCTURE AND CATALYTIC MECHANISM OF CELLOBIOHYDROLASE CELS, THE MAJOR ENZYMATIC COMPONENT OF THE CLOSTRIDIUM THERMOCELLUM CELLULOSOME | ALPHA/ALPHA BARREL, HYDROLASE
1l5g:A (GLY892) to (TRP953) CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN AVB3 IN COMPLEX WITH AN ARG-GLY-ASP LIGAND | GENU, HYBRID DOMAIN, BETA-TAIL DOMAIN, PSI DOMAIN, EGF DOMAIN, MIDAS, ADMIDAS, LIMBS, CAGE MOTIF, PROPELLER, A-DOMAIN, THIGH DOMAIN, CALF DOMAIN, RGD LIGAND, CELL ADHESION
4o9x:A (VAL948) to (ARG988) CRYSTAL STRUCTURE OF TCDB2-TCCC3 | BETA SHEET, COCOON, UNFOLDING, TC TOXIN, TOXIN
2yxv:B (LEU34) to (TYR69) THE DELETION MUTANT OF MULTICOPPER OXIDASE CUEO | MULTICOPPER OXIDASE, OXIDOREDUCTASE
4oic:A (VAL126) to (ASP170) CRYSTAL STRUCTRUAL OF A SOLUBLE PROTEIN | START FOLD, PYL-PHOSPHATASES COMPLEX, ABA SIGNALING PATHWAY, HORMONE RECEPTOR-HYDROLASE COMPLEX
1lnh:A (SER129) to (ALA163) LIPOXYGENASE-3(SOYBEAN) NON-HEME FE(II) METALLOPROTEIN | OXIDOREDUCTASE, METALLOPROTEIN, FE(II) COMPLEX
3k5d:B (ASN5) to (THR33) CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH AHM178 | ASPARTYL PROTEASE, ALZHEIMER'S DISEASE, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, MEMBRANE, PROTEASE, TRANSMEMBRANE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1xkn:A (GLU273) to (PRO299) CRYSTAL STRUCTURE OF THE PUTATIVE PEPTIDYL-ARGININE DEIMINASE FROM CHLOROBIUM TEPIDUM, NESG TARGET CTR21 | ALPHA-BETA PROTEIN, NESG, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM
4a5w:A (ASN245) to (THR285) CRYSTAL STRUCTURE OF C5B6 | IMMUNE SYSTEM, IMMUNITY, MEMBRANE ATTACK COMPLEX
3k7q:X (GLY298) to (PHE326) CRYSTAL STRUCTURE OF SUBSTRATE-BOUND 6-HYDROXY-L-NICOTINE OXIDASE FROM ARTHROBACTER NICOTINOVORANS | ENANTIOMERIC SUBSTRATES, FLAVOENZYMES, NICOTINE DEGRADATION, OXIDASE, OXIDOREDUCTASE
3k7t:A (GLY298) to (PHE326) CRYSTAL STRUCTURE OF APO-FORM 6-HYDROXY-L-NICOTINE OXIDASE, CRYSTAL FORM P3121 | ENANTIOMERIC SUBSTRATES, FLAVOENZYMES, NICOTINE DEGRADATION, OXIDASE, OXIDOREDUCTASE
4okq:A (ARG104) to (HIS148) CRYSTAL STRUCTURE OF THE SINGLE-STRANDED RNA BINDING PROTEIN HUTP FROM GEOBACILLUS THERMODENITRIFICANS | ANTITERMINATION, SINGLE STRANDED-RNA BINDING PROTEIN, RNA BINDING PROTEIN
4okq:B (ARG104) to (ASN147) CRYSTAL STRUCTURE OF THE SINGLE-STRANDED RNA BINDING PROTEIN HUTP FROM GEOBACILLUS THERMODENITRIFICANS | ANTITERMINATION, SINGLE STRANDED-RNA BINDING PROTEIN, RNA BINDING PROTEIN
2zht:A (PHE341) to (ALA368) CRYSTAL STRUCTURE OF BACE1 AT PH 4.5 | PH 4.5, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
2zhu:A (TYR342) to (ALA368) CRYSTAL STRUCTURE OF BACE1 AT PH 5.0 | PH 5.0, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
4ony:A (GLU208) to (ARG231) CRYSTAL STRUCTURE OF A ABC TRANSPORTER, PERIPLASMIC SUBSTRATE-BINDING PROTEIN FROM BRUCELLA MELITENSIS | SSGCID, ABC TRANSPORTER, PERIPLASMIC SUBSTRATE-BINDING PROTEIN, EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 5, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSPORT PROTEIN
4ony:B (GLU208) to (ARG231) CRYSTAL STRUCTURE OF A ABC TRANSPORTER, PERIPLASMIC SUBSTRATE-BINDING PROTEIN FROM BRUCELLA MELITENSIS | SSGCID, ABC TRANSPORTER, PERIPLASMIC SUBSTRATE-BINDING PROTEIN, EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 5, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSPORT PROTEIN
1m3i:C (VAL372) to (TRP428) PERFRINGOLYSIN O, NEW CRYSTAL FORM | PORE FORMING TOXIN
1m3i:D (GLU383) to (TRP428) PERFRINGOLYSIN O, NEW CRYSTAL FORM | PORE FORMING TOXIN
3kcp:B (ALA552) to (PRO599) CRYSTAL STRUCTURE OF INTERACTING CLOSTRIDIUM THERMOCELLUM MULTIMODULAR COMPONENTS | COHESIN, DOCKERIN, X-MODULE, CELLULOSOME, CARBOHYDRATE METABOLISM, CELL WALL BIOGENESIS/DEGRADATION, CELLULOSE DEGRADATION, GLYCOPROTEIN, POLYSACCHARIDE DEGRADATION, SECRETED, STRUCTURAL PROTEIN
1m4g:A (GLY47) to (ARG87) AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS- COMPLEX WITH COENZYME A AND RIBOSTAMYCIN | COA BINDING MOTIF, TRANSFERASE
4aa5:A (THR7) to (LYS54) P38ALPHA MAP KINASE BOUND TO CMPD 33 | SERINE/THREONINE KINASE, TRANSFERASE
4aac:A (THR7) to (LYS54) P38ALPHA MAP KINASE BOUND TO CMPD 29 | SERINE/THREONINE KINASE, TRANSFERASE
4or1:B (ALA23) to (ARG70) STRUCTURE AND MECHANISM OF FIBRONECTIN BINDING AND BIOFILM FORMATION OF ENTEROAGGREGATIVE ESCHERISCHIA COLI AAF FIMBRIAE | BIOFILM, CHAPERONE-USHER, PILUS, ADHESION, FIBRONECTIN, FIMBRIAE, FIBRE, IMMUNOGLOBULIN-LIKE, OUTER MEMBRANE PILUS, CELL ADHESION
3khw:A (GLY685) to (LYS738) CRYSTAL STRUCTURE OF THE LARGE C-TERMINAL DOMAIN OF POLYMERASE BASIC PROTEIN 2 FROM INFLUENZA VIRUS A/MEXICO/INDRE4487/2009(H1N1) | STRUCTURAL GENOMICS, PB2 C-TERMINAL DOMAIN, SWINE FLU, H1N1, NIAID, MRNA CAPPING, MRNA PROCESSING, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, VIRAL PROTEIN
4ow6:A (GLN387) to (ALA422) CRYSTAL STRUCTURE OF DIPHTHERIA TOXIN AT ACIDIC PH | DIPHTHERIA TOXIN TRANSLOCATION, MEMBRANE INSERTION, BICELLES, MEMBRANE CHANNELS
3klk:A (VAL1294) to (ASN1323) CRYSTAL STRUCTURE OF LACTOBACILLUS REUTERI N-TERMINALLY TRUNCATED GLUCANSUCRASE GTF180 IN TRICLINIC APO- FORM | NATIVE FORM, OPEN CONFORMATION, MULTIDOMAIN PROTEIN, GLYCOSYLTRANSFERASE, TRANSFERASE
3kll:A (VAL1294) to (ASN1323) CRYSTAL STRUCTURE OF LACTOBACILLUS REUTERI N-TERMINALLY TRUNCATED GLUCANSUCRASE GTF180-MALTOSE COMPLEX | GLUCANSUCRASE-MALTOSE COMPLEX, MULTIDOMAIN PROTEIN, GLYCOSYLTRANSFERASE, TRANSFERASE
4ahc:A (ILE54) to (GLU88) CRYSTAL STRUCTURE OF AN EVOLVED REPLICATING DNA POLYMERASE | TRANSFERASE, B FAMILY POLYMERASE, APOENZYME
4ahc:B (ILE54) to (GLU88) CRYSTAL STRUCTURE OF AN EVOLVED REPLICATING DNA POLYMERASE | TRANSFERASE, B FAMILY POLYMERASE, APOENZYME
4ai1:A (THR137) to (GLY168) FLO5A SHOWING A HEPTANUCLEAR GADOLINIUM CLUSTER ON ITS SURFACE AFTER 19 MIN OF SOAKING | CELL ADHESION, ADHESIN, FLOCCULIN
1ms0:B (GLY180) to (ASP212) MONOCLINIC FORM OF TRYPANOSOMA CRUZI TRANS-SIALIDASE, IN COMPLEX WITH 3-DEOXY-2,3-DEHYDRO-N-ACETYLNEURAMINIC ACID (DANA)AND LACTOSE | TRANSGLYCOSYLATION, BETA-PROPELLER, PROTEIN-CARBOHYDRATE INTERACTIONS, SIALIDASE, HYDROLASE
4ajv:A (GLU616) to (ASN657) STRUCTURE OF MOUSE ZP-C DOMAIN OF TGF-BETA-RECEPTOR-3 | SIGNALING PROTEIN
1mz5:A (GLY181) to (ASP213) TRYPANOSOMA RANGELI SIALIDASE | INIBITOR COMPLEX, TRYPANOSOMAL SIALIDASE, SIALYLTRANSFERASE, HYDROLASE
1ym2:A (ASN5) to (THR33) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE COMPLEXED WITH NVP-AUR200 | BETA-SECRETASE, MEMAPSIN2, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ym2:B (ASN5) to (THR33) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE COMPLEXED WITH NVP-AUR200 | BETA-SECRETASE, MEMAPSIN2, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ym2:C (ASN5) to (THR33) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE COMPLEXED WITH NVP-AUR200 | BETA-SECRETASE, MEMAPSIN2, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1n12:A (HIS38) to (ASN88) CRYSTAL STRUCTURE OF THE PAPE (N-TERMINAL-DELETED) PILUS SUBUNIT BOUND TO A PEPTIDE CORRESPONDING TO THE N-TERMINAL EXTENSION OF THE PAPK PILUS SUBUNIT (RESIDUES 1-11) FROM UROPATHOGENIC E. COLI | IMMUNOGLOBULIN-LIKE FOLD, DONOR STRAND COMPLEMENTATION, DONOR STRAND EXCHANGE, CHAPERONE PRIMING, PILUS FIBER ASSEMBLY, ORGANELLE BIOGENESIS
1n12:C (HIS38) to (ASN88) CRYSTAL STRUCTURE OF THE PAPE (N-TERMINAL-DELETED) PILUS SUBUNIT BOUND TO A PEPTIDE CORRESPONDING TO THE N-TERMINAL EXTENSION OF THE PAPK PILUS SUBUNIT (RESIDUES 1-11) FROM UROPATHOGENIC E. COLI | IMMUNOGLOBULIN-LIKE FOLD, DONOR STRAND COMPLEMENTATION, DONOR STRAND EXCHANGE, CHAPERONE PRIMING, PILUS FIBER ASSEMBLY, ORGANELLE BIOGENESIS
1n1v:A (GLY184) to (ASP216) TRYPANOSOMA RANGELI SIALIDASE IN COMPLEX WITH DANA | BETA PROPELLER, LECTIN-LIKE FOLD, HYDROLASE
3kyr:C (ASN5) to (THR33) BACE-1 IN COMPLEX WITH A NORSTATINE TYPE INHIBITOR | BACE, BETA-SECRETASE, MEMAPSIN-2, ASPARTYL PROTEASE, INHIBITOR, NORSTATINE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5ddy:E (SER463) to (VAL493) BINARY COMPLEX OF HUMAN POLYMERASE LAMBDA WITH DCTP | POLYMERASE LAMBDA, TRANSFERASE
3abz:B (TYR716) to (GLY747) CRYSTAL STRUCTURE OF SE-MET LABELED BETA-GLUCOSIDASE FROM KLUYVEROMYCES MARXIANUS | GLYCOSIDE HYDROLASE FAMILY3 BETA-GLUCOSIDASE, PA14 DOMAIN, HYDROLASE
3abz:C (TYR716) to (GLY747) CRYSTAL STRUCTURE OF SE-MET LABELED BETA-GLUCOSIDASE FROM KLUYVEROMYCES MARXIANUS | GLYCOSIDE HYDROLASE FAMILY3 BETA-GLUCOSIDASE, PA14 DOMAIN, HYDROLASE
1yoj:A (GLY281) to (GLU341) CRYSTAL STRUCTURE OF SRC KINASE DOMAIN | PROTEIN TYROSINE KINASE, TRANSFERASE
4phx:A (THR23) to (LYS65) CRYSTAL STRUCTURE OF AGGB, THE MINOR SUBUNIT OF AGGREGATIVE ADHERENCE FIMBRIAE TYPE I FROM THE ESCHERICHIA COLI O4H104 | IG-LIKE FOLD, BETA SANDWICH, DONOR-STRAND COMPLEMENTATION, CELL ADHESION
4phx:E (THR23) to (GLY67) CRYSTAL STRUCTURE OF AGGB, THE MINOR SUBUNIT OF AGGREGATIVE ADHERENCE FIMBRIAE TYPE I FROM THE ESCHERICHIA COLI O4H104 | IG-LIKE FOLD, BETA SANDWICH, DONOR-STRAND COMPLEMENTATION, CELL ADHESION
5di0:A (ASN246) to (ASP305) CRYSTAL STRUCTURE OF DLN1 | PORE-FORMING PROTEIN, AEOLYSIN-LIKE PROTEIN, VETEBRATE, HIGH-MANNOSE GLYCANS, COMPLEX, SUGAR BINDING PROTEIN
1n67:A (TYR372) to (ASN401) CLUMPING FACTOR A FROM STAPHYLOCOCCUS AUREUS | DEV-IGG, IGG, IMMUNOGLOBULIN, IGSF, CLUMPING FACTOR, STAPHYLOCOCCUS AUREUS, FIBRINONGEN-BINDING, CELL ADHESION
3afq:B (ASP16) to (TRP60) CRYSTAL STRUCTURE OF THE SINGLE-STRANDED DNA BINDING PROTEIN FROM MYCOBACTERIUM LEPRAE (FORM II) | OB-FOLD, QUATERNARY STRUCTURE AND STABILITY, CHANGES ON OLIGOMERISATION, WATER-BRIDGES, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, DNA-BINDING, DNA BINDING PROTEIN
1yvu:A (ILE126) to (ILE163) CRYSTAL STRUCTURE OF A. AEOLICUS ARGONAUTE | RNASE H FOLD, RNA BINDING PROTEIN, GENE REGULATION
1yw4:A (THR283) to (GLU326) CRYSTAL STRUCTURE OF THE SUCCINYLGLUTAMATE DESUCCINYLASE FROM CHROMOBACTERIUM VIOLACEUM, NORTHEAST STRUCTURAL GENOMICS TARGET CVR22. | ALPHA-BETA PROTEIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, HYDROLASE
5dmb:D (GLU11) to (ALA37) CRYSTAL STRUCTURE OF A TRANSLATIONAL REGULATOR BOUND TO A FLAGELLAR ASSEMBLY FACTOR | TRANSLATION, FLAGELLUM, ASSEMBLY FACTOR
3aib:A (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE | BETA-ALPHA-BARREL, TRANSFERASE
3aib:C (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE | BETA-ALPHA-BARREL, TRANSFERASE
3aib:G (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE | BETA-ALPHA-BARREL, TRANSFERASE
3aib:E (VAL751) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE | BETA-ALPHA-BARREL, TRANSFERASE
3aib:F (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE | BETA-ALPHA-BARREL, TRANSFERASE
3aib:H (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE | BETA-ALPHA-BARREL, TRANSFERASE
3aic:A (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
3aic:B (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
3aic:C (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
3aic:F (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
3aic:G (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
3aic:H (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
4al2:A (ASN74) to (LEU99) PEPTIDE DEFORMYLASE (NI-FORM) WITH HYDROSULFIDE | HYDROLASE, OXIDATION-REDUCTION
3aie:A (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
3aie:B (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
3aie:C (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
3aie:D (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
3aie:F (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
3aie:H (SER748) to (SER780) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
4amc:A (VAL1295) to (SER1324) CRYSTAL STRUCTURE OF LACTOBACILLUS REUTERI 121 N-TERMINALLY TRUNCATED GLUCANSUCRASE GTFA | TRANSFERASE, GLYCOSYLTRANSFERASE, REUTERANSUCRASE
3le2:A (TYR211) to (PRO241) STRUCTURE OF ARABIDOPSIS ATSERPIN1. NATIVE STRESSED CONFORMATION | PLANT SERPIN SERPIN-ZX ARATHZX SERPIN-1 ATSERPIN1, APOPLAST, GLYCOPROTEIN, PROTEASE INHIBITOR, SECRETED, SERINE PROTEASE INHIBITOR, HYDROLASE
5dqc:B (ASN5) to (THR33) CO-CRYSTAL OF BACE1 WITH COMPOUND 0211 | B-SECRETASE, INHIBITOR, ALZHEIMER'S DISEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4aq6:C (TYR271) to (PRO315) SUBSTRATE BOUND HOMOGENTISATE 1,2-DIOXYGENASE | OXIDOREDUCTASE, EXTRADIOL-TYPE, EXTRADIOL-TYPE DIOXYGENASE
1zk5:A (SER107) to (GLN140) ESCHERICHIA COLI F17FG LECTIN DOMAIN COMPLEX WITH N-ACETYLGLUCOSAMINE | LECTIN, BETA SANDWICH, PROTEIN-STRUCTURE COMPLEX, IMMUNOGLOBULIN-LIKE FOLD, CELL ADHESION
4q6u:B (GLY162) to (ARG207) CRYSTAL STRUCTURE OF A PUTATIVE UNCHARACTERIZED PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS | SEATTLE STRUCTURAL GENOICS FOR INFECTIOUS DISEASE, MYCOBACTERIUM TUBERCULOSIS, STRUCTURAL GENOMICS, SSGCID, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, UNKNOWN FUNCTION
5e6s:A (MET72) to (SER101) STRUCTURES OF LEUKOCYTE INTEGRIN ALB2: THE AI DOMAIN, THE HEADPIECE, AND THE POCKET FOR THE INTERNAL LIGAND | LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1, CELL ADHESION
4ayg:A (VAL1294) to (ASN1323) LACTOBACILLUS REUTERI N-TERMINALLY TRUNCATED GLUCANSUCRASE GTF180 IN ORTHORHOMBIC APO-FORM | TRANSFERASE, GLYCOSYLTRANSFERASE, GLYCOSYL HYDROLASE FAMILY 70, CIRCULARLY PERMUTED BETA-ALPHA BARREL
4ayg:B (VAL1294) to (ASN1323) LACTOBACILLUS REUTERI N-TERMINALLY TRUNCATED GLUCANSUCRASE GTF180 IN ORTHORHOMBIC APO-FORM | TRANSFERASE, GLYCOSYLTRANSFERASE, GLYCOSYL HYDROLASE FAMILY 70, CIRCULARLY PERMUTED BETA-ALPHA BARREL
1zz8:B (PRO91) to (THR126) CRYSTAL STRUCTURE OF FEII HPPE IN COMPLEX WITH SUBSTRATE FORM 2 | SUBSTRATE-ENZYME COMPLEX, CUPIN, MONONUCLEAR IRON ENZYME, OXIDOREDUCTASE
4b05:A (ASN5) to (ASN28) PRECLINICAL CHARACTERIZATION OF AZD3839, A NOVEL CLINICAL CANDIDATE BACE1 INHIBITOR FOR THE TREATMENT OF ALZHEIMER DISEASE | HYDROLASE, AMINOISOINDOLE, ALZHEIMER'S DISEASE
4b1c:A (ASN5) to (ASN28) NEW AMINOIMIDAZOLES AS BACE-1 INHIBITORS: FROM RATIONAL DESIGN TO AB-LOWERING IN BRAIN | HYDROLASE, LEAD GENERATION, STRUCTURE-BASED DRUG DESIGN, INHIBITOR
4b1e:A (TYR342) to (ALA368) NEW AMINOIMIDAZOLES AS BACE-1 INHIBITORS: FROM RATIONAL DESIGN TO AB-LOWERING IN BRAIN | HYDROLASE, STRUCTURE-BASED DRUG DESIGN
5e8w:A (GLY212) to (SER235) TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D) IN COMPLEX WITH STAUROSPORINE | ALK5, KINASE DOMAIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5e8z:A (GLY212) to (SER235) TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D) IN COMPLEX WITH 3- AMINO-6-[4-(2-HYDROXYETHYL)PHENYL]-N-[4-(MORPHOLIN-4-YL)PYRIDIN-3- YL]PYRAZINE-2-CARBOXAMIDE | ALK5, KINASE DOMAIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3m07:A (PHE534) to (GLN589) 1.4 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF PUTATIVE ALPHA AMYLASE FROM SALMONELLA TYPHIMURIUM. | PUTATIVE ALPHA AMYLASE, IDP00968, CSGID, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, UNKNOWN FUNCTION
4qcl:A (LEU346) to (ASN382) CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF HUMAN DNA POLYMERASE ALPHA IN TERNARY COMPLEX WITH AN RNA-PRIMED DNA TEMPLATE AND DCTP | B-FAMILY DNA POLYMERASE, DNA REPLICATION, TRANSFERASE-DNA-RNA COMPLEX
3azo:B (THR121) to (MSE147) CRYSTAL STRUCTURE OF PUROMYCIN HYDROLASE | POP FAMILY, HYDROLASE
4b77:A (ASN5) to (ASN28) AMINOIMIDAZOLES AS BACE-1 INHIBITORS: FROM DE NOVO DESIGN TO AB-LOWERING IN BRAIN | HYDROLASE, LEAD GENERATION, STRUCTURE-BASED DRUG DESIGN
4b77:A (TYR342) to (ALA368) AMINOIMIDAZOLES AS BACE-1 INHIBITORS: FROM DE NOVO DESIGN TO AB-LOWERING IN BRAIN | HYDROLASE, LEAD GENERATION, STRUCTURE-BASED DRUG DESIGN
4qg5:D (ARG99) to (SER134) CRYSTAL STRUCTURE OF PHOSPHOGLUCOMUTASE FROM LEISHMANIA MAJOR AT 3.5 ANGSTROM RESOLUTION | PHOSPHOHEXOMUTASE, PHOSPHOTRANSFERASE, METAL-BINDING REGION, ALPHA AND BETA PROTEINS, ISOMERASE
5eg9:A (THR329) to (GLY359) THE CAP BINDING SITE OF INFLUENZA VIRUS PROTEIN PB2 AS A DRUG TARGET | PB2 CAP, VIRAL PROTEIN
4ba1:I (SER6) to (VAL47) ARCHAEAL EXOSOME (RRP4-RRP41(D182A)-RRP42) BOUND TO INORGANIC PHOSPHATE | HYDROLASE, RNA DEGRADATION,
4qn9:A (GLU234) to (GLY274) STRUCTURE OF HUMAN NAPE-PLD | PLD, NAPE, ANANDAMIDE, BILE ACID, PHOSPHOLIPASE, INFLAMMATION, PAIN, COMPLEX, NAE, AEA, OEA, PEA, MBL, PE, CANNABINOID, FAT, ACYL, DEOXYCHOLATE, OBESITY, PHOSPHOLIPID, MEMBRANE, STEROID, DRUG, ALPHA- BETA-BETA-ALPHA FOLD, PHOSPHODIESTERASE, HYDROLASE
4qn9:B (GLU234) to (GLY274) STRUCTURE OF HUMAN NAPE-PLD | PLD, NAPE, ANANDAMIDE, BILE ACID, PHOSPHOLIPASE, INFLAMMATION, PAIN, COMPLEX, NAE, AEA, OEA, PEA, MBL, PE, CANNABINOID, FAT, ACYL, DEOXYCHOLATE, OBESITY, PHOSPHOLIPID, MEMBRANE, STEROID, DRUG, ALPHA- BETA-BETA-ALPHA FOLD, PHOSPHODIESTERASE, HYDROLASE
4bdv:B (PRO2142) to (GLY2168) CRYSTAL STRUCTURE OF A TRUNCATED B-DOMAIN HUMAN FACTOR VIII | BLOOD CLOTTING, BLOOD COAGULATION, METAL BINDING
3mj5:B (GLY194) to (LEU235) SEVERE ACUTE RESPIRATORY SYNDROME-CORONAVIRUS PAPAIN-LIKE PROTEASE INHIBITORS: DESIGN, SYNTHESIS, PROTEIN-LIGAND X-RAY STRUCTURE AND BIOLOGICAL EVALUATION | NON-COVALENT INHIBITOR, CYSTEINE PROTEASE, SARS CORONAVIRUS, ZINC- FINGER, VIRAL PROTEIN
3mj9:A (ARG124) to (SER157) CRYSTAL STRUCTURE OF JAML IN COMPLEX WITH THE STIMULATORY ANTIBODY HL4E10 | IMMUNOGLOBULIN TANDEM DOMAIN, RECEPTOR-ANTIBODY COMPLEX, CELL ADHESION, CELL JUNCTION, GLYCOPROTEIN, IMMUNOGLOBULIN DOMAIN, MEMBRANE, COSTIMULATION, HAMSTER IGG, TRANSMEMBRANE, IMMUNE SYSTEM
5es4:D (ARG344) to (ASN372) RE-REFINEMENT OF INTEGRIN ALPHAXBETA2 ECTODOMAIN IN THE CLOSED/BENT CONFORMATION | COMPLEMENT RECEPTOR-4 ALPHAXBETA2, CELL ADHESION
4bgf:C (ALA145) to (ALA167) THE 3D-STRUCTURE OF ARYLAMINE-N-ACETYLTRANSFERASE FROM M. TUBERCULOSIS | TRANSFERASE, DRUG DESIGN, CROSS-SEEDING, MICRO-SEEDING, MICROSEED MATRIX SCREEN,
4bk4:A (GLY180) to (ASP216) CRYSTAL STRUCTURE OF THE HUMAN EPHA4 ECTODOMAIN | SIGNALING PROTEIN, CELL ADHESION, CELL REPULSION, RECEPTOR CLUSTERING, RECEPTOR CIS INTERACTION, EPH-EPHRIN CRYSTAL STRUCTURES, EPH ECTODOMAIN, ERYTHROPOETIN-PRODUCING HEPATOCELLULAR RECEPTOR, LBD, EGF, FN
4bkf:A (GLY180) to (ASP216) CRYSTAL STRUCTURE OF THE HUMAN EPHA4 ECTODOMAIN IN COMPLEX WITH HUMAN EPHRINB3 | TRANSFERASE, CELL ADHESION, CELL REPULSION, RECEPTOR CLUSTERING, RECEPTOR CIS INTERACTION, ERYTHROPOETIN-PRODUCING HEPATOCELLULAR RECEPTOR, LBD, SUSHI, EGF, FN
5f00:A (ASN66) to (ASN89) CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-[3-[(3-CHLORO-8- QUINOLYL)AMINO]PHENYL]-5-METHYL-2,6-DIHYDRO-1,4-OXAZIN-3-AMINE | PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, HYDROLASE
3mx0:A (GLY177) to (GLU213) CRYSTAL STRUCTURE OF EPHA2 ECTODOMAIN IN COMPLEX WITH EPHRIN-A5 | ECTODOMAIN, RECEPTOR-LIGAND COMPLEX, RECEPTOR-RECEPTOR INTERACTION, TRANSFERASE RECEPTOR-SIGNALLING PROTEIN COMPLEX
3buf:A (ASN5) to (ASN28) BACE-1 COMPLEXED WITH COMPOUND 2 | ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, BETA-SECRETASE, MEMAPSIN 2, FRAGMENT SCREEN, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
4r04:A (ASN1514) to (VAL1545) CLOSTRIDIUM DIFFICILE TOXIN A (TCDA) | GLUCOSLY TRANSFERASE, TRANSFERASE
5fdx:B (LEU616) to (LEU657) STRUCTURE OF DDR1 RECEPTOR TYROSINE KINASE IN COMPLEX WITH D2164 INHIBITOR AT 2.65 ANGSTROMS RESOLUTION. | DDR1 KINASE, INHIBITORS, STRUCTURAL GENOMICS, PSI-BIOLOGY, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
4rce:A (ASN5) to (ASN28) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH AMINOOXAZOLINE XANTHENE INHIBITOR 2 | ASPARTIC PROTEASE, ALZHEIMER'S DISEASE, APP, AMYLOID PRECURSOR PROTEIN, BRAIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4rcf:A (ASN5) to (ASN28) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH 2-AMINOOXAZOLINE 4- FLUOROXANTHENE INHIBITOR 49 | ASPARTIC PROTEASE, ALZHEIMER'S DISEASE, APP, AMYLOID PRECURSOR PROTEIN, BRAIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4re6:B (GLY186) to (ALA215) ACYLAMINOACYL PEPTIDASE COMPLEXED WITH A CHLOROMETHYLKETONE INHIBITOR | BETA-PROPELLER, ALPHA-BETA-HYDROLASE FOLD, CHLOROMETHYL-KETONE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3cgn:A (ALA89) to (ASN118) CRYSTAL STRUCTURE OF THERMOPHILIC SLYD | SLYD, PROLYL CIS TRANS ISOMERASE, CHAPERONE, ROTAMASE, ISOMERASE
3nh3:X (GLY298) to (PHE326) COMPLEX OF 6-HYDROXY-L-NICOTINE OXIDASE WITH FINAL KETONE PRODUCT FORMED DURING CATALYTIC TURNOVER | ENANTHIOMERIC SUBSTRATE-INHIBITOR, FLAVOENZYMES, NICOTINE DEGRADATION, OXIDOREDUCTASE
3nho:X (GLY298) to (PHE326) COMPLEX OF 6-HYDROXY-L-NICOTINE OXIDASE WITH PRODUCT BOUND AT ACTIVE SITE | ENANTHIOMERIC SUBSTRATE-INHIBITOR, FLAVOENZYMES, NICOTINE DEGRADATION, OXIDOREDUCTASE
5fmm:A (THR329) to (GLY359) CRYSTAL STRUCTURE OF THE MID, CAP-BINDING, MID-LINK AND 627 DOMAINS FROM AVIAN INFLUENZA A VIRUS POLYMERASE PB2 SUBUNIT BOUND TO M7GTP | VIRAL PROTEIN, INFLUENZA A PB2-C REGION CONTAINING MID, CAP-BINDING, MID-LINK, 627 AND NLS DOMAINS
3njx:A (ASN192) to (SER229) RHAMNOGALACTURONAN LYASE FROM ASPERGILLUS ACULEATUS MUTANT H210A | CARBOHYDRATE ACTIVE ENZYME, LYASE, PECTIN DEGRADATION, POLYSACCHARIDE LYASE FAMILY 4
3nk0:X (GLY298) to (PHE326) COMPLEX OF 6-HYDROXY-L-NICOTINE OXIDASE WITH INHIBITOR BOUND AT ACTIVE SITE AND TURNOVER PRODUCT AT EXIT CAVITY | ENANTHIOMERIC SUBSTRATE-INHIBITOR, FLAVOENZYMES, NICOTINE DEGRADATION, OXIDOREDUCTASE
3nn0:X (GLY298) to (PHE326) COMPLEX OF 6-HYDROXY-L-NICOTINE OXIDASE WITH NICOTINAMIDE | ENANTHIOMERIC SUBSTRATE-INHIBITOR, FLAVOENZYMES, NICOTINE DEGRADATION, FAD FOLD, AMINO OXIDASE, FAD BINDING, CYTOSOL, OXIDOREDUCTASE
5fr2:B (LYS127) to (PRO161) FARNESYLATED RHOA-GDP IN COMPLEX WITH RHOGDI-ALPHA, LYSINE ACETYLATED AT K178 | SIGNALING PROTEIN, LYSINE-ACETYLATION, RHOA, RAS-SUPERFAMILY, RHOGDI, CYTOSKELETON, GDP
4cb6:B (THR329) to (GLY359) STRUCTURE OF INFLUENZA A H5N1 PB2 CAP-BINDING DOMAIN WITH BOUND CAP ANALOGUE (COMPOUND 11) | TRANSFERASE, INFLUENZA POLYMERASE, M7GTP, CAP-BINDING INHIBITORS
4cb7:B (THR329) to (GLY359) STRUCTURE OF INFLUENZA A H5N1 PB2 CAP-BINDING DOMAIN WITH BOUND CAP ANALOGUE (COMPOUND 8E) | TRANSCRIPTION, CAP-BINDING INHIBITORS
3nsg:A (MSE1) to (GLN46) CRYSTAL STRUCTURE OF OMPF, AN OUTER MEMBRANE PROTEIN FROM SALMONELLA TYPHI | PORIN, BETA BARREL, OUTER MEMBRANE PROTEIN, BETA BARREL MEMBRANE PROTEIN, MEMBRANE PROTEIN
4rn5:A (LYS397) to (GLY423) B1 DOMAIN OF HUMAN NEUROPILIN-1 WITH ACETATE ION IN A LIGAND-BINDING SITE | VEGF BINDING, PROTEIN BINDING
4rqq:A (LEU27) to (LEU50) CRYSTAL STRUCTURE OF HUMAN FAB PGDM1400, A BROADLY REACTIVE AND POTENT HIV-1 NEUTRALIZING ANTIBODY | IGG, ANTI-HIV-1 ANTIBODY, HIV-1 ENV TRIMER, IMMUNE SYSTEM
4rtd:A (GLN1608) to (GLY1643) ESCHERICHIA COLI ALPHA-2-MACROGLOBULIN ACTIVATED BY PORCINE ELASTASE | THIOESTER DOMAIN, MACROGLOBULIN, LIPID BINDING PROTEIN
4ry5:A (LEU362) to (ASP387) C-TERMINAL MUTANT (W550N) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4s0h:E (HIS170) to (PHE206) TBX5 DB, NKX2.5 HD, ANF DNA COMPLEX | TRANSCRIPTION FACTOR, TRANSCRIPTION-DNA COMPLEX
3d7p:B (MET13) to (LYS48) CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN (TTR) AT PH 4.0 | WT-TTR, AMYLOID, TRANSTHYRETIN, ACIDIC PH, NATIVE TTR, AND CRYSTAL STRUCTURE, DISEASE MUTATION, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HORMONE, POLYMORPHISM, POLYNEUROPATHY, RETINOL-BINDING, SECRETED, THYROID HORMONE, TRANSPORT, VITAMIN A, TRANSPORT PROTEIN
3od3:A (LEU34) to (TYR69) CUEO AT 1.1 A RESOLUTION INCLUDING RESIDUES IN PREVIOUSLY DISORDERED REGION | MULTICOPPER OXIDASE, CU(I) OXIDASE, OXIDOREDUCTASE
3djl:A (TRP215) to (PRO241) CRYSTAL STRUCTURE OF ALKYLATION RESPONSE PROTEIN E. COLI AIDB | ALPHA HELIX, BETA-BARREL, FAD, FLAVOPROTEIN, OXIDOREDUCTASE
4txk:A (GLU174) to (GLN199) CONSTRUCT OF MICAL-1 CONTAINING THE MONOOXYGENASE AND CALPONIN HOMOLOGY DOMAINS | MONOOYXGENASE, CALPONIN HOMOLOGY, MICAL, OXIDOREDUCTASE
5guh:A (GLY800) to (VAL834) CRYSTAL STRUCTURE OF SILKWORM PIWI-CLADE ARGONAUTE SIWI BOUND TO PIRNA | NUCLEASE, RNASEH, HYDROLASE-RNA COMPLEX
4tyh:B (PRO6) to (ARG57) TERNARY COMPLEX OF P38 AND MK2 WITH A P38 INHIBITOR | P38, MK2, P38 INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4d70:B (LEU64) to (HIS109) STRUCTURAL, BIOPHYSICAL AND BIOCHEMICAL ANALYSES OF A CLOSTRIDIUM PERFRINGENS SORTASE D5 TRANSPEPTIDASE | HYDROLASE
4d7w:A (TYR102) to (HIS149) CRYSTAL STRUCTURE OF SORTASE C1 (SRTC1) FROM STREPTOCOCCUS AGALACTIAE | HYDROLASE, PILUS, GRAM-POSITIVE
4d8c:A (ASN5) to (ASN28) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE IN COMPLEX WITH NVP-BXD552, DERIVED FROM A CO-CRYSTALLIZATION EXPERIMENT | BETA-SECRETASE, MEMAPSIN2, BACE1, ASPARTIC PROTEINASE, ALZHEIMER'S DISEASE, ENZYME INHIBITOR COMPLEX, STRUCTURE-BASED DRUG DESIGN, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4d8c:B (ASN5) to (ASN28) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE IN COMPLEX WITH NVP-BXD552, DERIVED FROM A CO-CRYSTALLIZATION EXPERIMENT | BETA-SECRETASE, MEMAPSIN2, BACE1, ASPARTIC PROTEINASE, ALZHEIMER'S DISEASE, ENZYME INHIBITOR COMPLEX, STRUCTURE-BASED DRUG DESIGN, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4d8c:C (ASN5) to (ASN28) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE IN COMPLEX WITH NVP-BXD552, DERIVED FROM A CO-CRYSTALLIZATION EXPERIMENT | BETA-SECRETASE, MEMAPSIN2, BACE1, ASPARTIC PROTEINASE, ALZHEIMER'S DISEASE, ENZYME INHIBITOR COMPLEX, STRUCTURE-BASED DRUG DESIGN, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5h8j:F (GLY221) to (ASP254) CRYSTAL STRUCTURE OF MEDICAGO TRUNCATULA N-CARBAMOYLPUTRESCINE AMIDOHYDROLASE (MTCPA) IN COMPLEX WITH CADAVERINE | AMIDASE, HELICAL OCTAMER, ALPHA-BETA-BETA-ALPHA SANDWICH FOLD, PUTRESCINE BIOSYNTHESIS, HYDROLASE
5h8j:G (GLY221) to (ASP254) CRYSTAL STRUCTURE OF MEDICAGO TRUNCATULA N-CARBAMOYLPUTRESCINE AMIDOHYDROLASE (MTCPA) IN COMPLEX WITH CADAVERINE | AMIDASE, HELICAL OCTAMER, ALPHA-BETA-BETA-ALPHA SANDWICH FOLD, PUTRESCINE BIOSYNTHESIS, HYDROLASE
5h8l:A (GLY221) to (ASP254) CRYSTAL STRUCTURE OF MEDICAGO TRUNCATULA N-CARBAMOYLPUTRESCINE AMIDOHYDROLASE (MTCPA) C158S MUTANT IN COMPLEX WITH PUTRESCINE | AMIDASE, HELICAL OCTAMER, ALPHA-BETA-BETA-ALPHA SANDWICH FOLD, HYDROLASE
3dsn:C (GLY44) to (SER93) CRYSTAL STRUCTURE OF THE COMPLEX OF THE CAF1M CHAPERONE WITH THE MINI-FIBER OF TWO CAF1 SUBUNITS (CAF1:CAF1), CARRYING THE THR7PHE MUTATION IN THE GD DONOR STRAND | CHAPERONE, FIMBRIAL SUBUNIT, FIMBRIAE, DONOR STRAND COMPLEMENTATION, PROTEIN-PROTEIN COMPLEX, BETA BARREL, IMMUNOGLOBULIN DOMAIN, PERIPLASM, PLASMID, CAPSULE, SECRETED
3dsn:F (GLY44) to (SER93) CRYSTAL STRUCTURE OF THE COMPLEX OF THE CAF1M CHAPERONE WITH THE MINI-FIBER OF TWO CAF1 SUBUNITS (CAF1:CAF1), CARRYING THE THR7PHE MUTATION IN THE GD DONOR STRAND | CHAPERONE, FIMBRIAL SUBUNIT, FIMBRIAE, DONOR STRAND COMPLEMENTATION, PROTEIN-PROTEIN COMPLEX, BETA BARREL, IMMUNOGLOBULIN DOMAIN, PERIPLASM, PLASMID, CAPSULE, SECRETED
3opz:A (GLY111) to (LYS160) CRYSTAL STRUCTURE OF TRANS-SIALIDASE IN COMPLEX WITH THE FAB FRAGMENT OF A NEUTRALIZING MONOCLONAL IGG ANTIBODY | SIX-BLADED BETA-PROPELLER NEURAMINIDASE IMMUNOGLOBULIN DOMAIN, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX, HYDROLASE-IMMUNE SYSTEM COMPLEX
3opz:B (GLY111) to (LYS160) CRYSTAL STRUCTURE OF TRANS-SIALIDASE IN COMPLEX WITH THE FAB FRAGMENT OF A NEUTRALIZING MONOCLONAL IGG ANTIBODY | SIX-BLADED BETA-PROPELLER NEURAMINIDASE IMMUNOGLOBULIN DOMAIN, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX, HYDROLASE-IMMUNE SYSTEM COMPLEX
3opz:C (GLY111) to (LYS160) CRYSTAL STRUCTURE OF TRANS-SIALIDASE IN COMPLEX WITH THE FAB FRAGMENT OF A NEUTRALIZING MONOCLONAL IGG ANTIBODY | SIX-BLADED BETA-PROPELLER NEURAMINIDASE IMMUNOGLOBULIN DOMAIN, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX, HYDROLASE-IMMUNE SYSTEM COMPLEX
4dbb:A (ILE550) to (GLU595) THE PTB DOMAIN OF MINT1 IS AUTOINHIBITED BY A HELIX IN THE C-TERMINAL LINKER REGION | X11S/MINTS, PTB DOMAIN, CHIMERA PROTEIN, PROTEIN TRANSPORT
3dur:C (SER26) to (TRP50) CRYSTAL STRUCTURE OF SAG173-04 | ANTIBODY, KDO, TWINNING, PSEUDO-SYMMETRY, IMMUNE SYSTEM
3dus:C (SER26) to (TRP50) CRYSTAL STRUCTURE OF SAG506-01, ORTHORHOMBIC, TWINNED, CRYSTAL 1 | ANTIBODY, KDO, TWINNING, PSEUDO-SYMMETRY, IMMUNE SYSTEM
3dv1:A (ASN5) to (THR33) CRYSTAL STRUCTURE OF HUMAN BETA-SECRETASE IN COMPLEX WITH NVP-ARV999 | BETA-SECRETASE, BACE1, MEMAPSIN2, ASPARTIC PROTEASE, ENZYME INHIBITOR COMPLEX, ALZHEIMER'S DISEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
3dv1:C (ASN5) to (THR33) CRYSTAL STRUCTURE OF HUMAN BETA-SECRETASE IN COMPLEX WITH NVP-ARV999 | BETA-SECRETASE, BACE1, MEMAPSIN2, ASPARTIC PROTEASE, ENZYME INHIBITOR COMPLEX, ALZHEIMER'S DISEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
3dv6:A (SER26) to (TRP50) CRYSTAL STRUCTURE OF SAG506-01, TETRAGONAL, CRYSTAL 2 | ANTIBODY, KDO, TWINNING, PSEUDO-SYMMETRY, IMMUNE SYSTEM
5hcc:A (VAL934) to (GLY981) TERNARY COMPLEX OF HUMAN COMPLEMENT C5 WITH ORNITHODOROS MOUBATA OMCI AND DERMACENTOR ANDERSONI RACI3. | COMPLEMENT, INFLAMMATION, INHIBITOR, TICK, IMMUNE SYSTEM
5hee:A (LEU56) to (GLU80) CRYSTAL STRUCTURE OF THE TK2203 PROTEIN | PUTATIVE, DIOXYGENASE, OXIDOREDUCTASE
5heh:A (VAL154) to (TYR193) PENTAMERIC LIGAND-GATED ION CHANNEL GLIC MUTANT P246A | PENTAMERIC LIGAND-GATED ION CHANNELS, MEMBRANE PROTEIN, LIGAND-GATED ION CHANNEL, TRANSPORT PROTEIN
5heh:B (VAL154) to (TYR193) PENTAMERIC LIGAND-GATED ION CHANNEL GLIC MUTANT P246A | PENTAMERIC LIGAND-GATED ION CHANNELS, MEMBRANE PROTEIN, LIGAND-GATED ION CHANNEL, TRANSPORT PROTEIN
5heh:C (VAL154) to (TYR193) PENTAMERIC LIGAND-GATED ION CHANNEL GLIC MUTANT P246A | PENTAMERIC LIGAND-GATED ION CHANNELS, MEMBRANE PROTEIN, LIGAND-GATED ION CHANNEL, TRANSPORT PROTEIN
5heh:D (VAL154) to (TYR193) PENTAMERIC LIGAND-GATED ION CHANNEL GLIC MUTANT P246A | PENTAMERIC LIGAND-GATED ION CHANNELS, MEMBRANE PROTEIN, LIGAND-GATED ION CHANNEL, TRANSPORT PROTEIN
4deq:B (LYS124) to (GLY150) STRUCTURE OF THE NEUROPILIN-1/VEGF-A COMPLEX | COAGULATION FACTOR DOMAIN, HEPARIN BINDING DOMAIN, ANGIOGENESIS, PROTEIN BINDING-CYTOKINE COMPLEX
4di2:C (ASN5) to (ASN28) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH HYDROXYETHYLAMINE INHIBITOR 37 | MEMAPSIN-2, ALZHEIMER'S DISEASE, PROTEASE, BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1, APP, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3p79:A (THR7) to (LYS54) P38 INHIBITOR-BOUND | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4drf:B (PRO26) to (ILE59) CRYSTAL STRUCTURE OF BACTERIAL PNKP-C/HEN1-N HETERODIMER | RNA REPAIR, RNA LIGASE, LIGASE-ACTIVATING, PROTEIN BINDING, TRANSFERASE
4drf:D (PRO26) to (ILE56) CRYSTAL STRUCTURE OF BACTERIAL PNKP-C/HEN1-N HETERODIMER | RNA REPAIR, RNA LIGASE, LIGASE-ACTIVATING, PROTEIN BINDING, TRANSFERASE
3pgp:A (SER52) to (ALA84) CRYSTAL STRUCTURE OF PA4794 - GNAT SUPERFAMILY PROTEIN IN COMPLEX WITH ACCOA | STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, ACETYLTRANSFERASE, GNAT FAMILY, PSI, TRANSFERASE
5i3v:A (ASN5) to (ASN28) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH AMINOQUINOLINE COMPOUND 1 | ASPARTIC PROTEASE, AMYLOID PRECURSOR PROTEIN, ALZHEIMER'S DISEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5i3w:A (ASN5) to (ASN28) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH 2-AMINOOXAZOLINE-3- AZAXANTHENE INHIBITOR 2 | ASPARTIC PROTEASE, AMYLOID PRECURSOR PROTEIN, ALZHEIMER'S DISEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4e1j:D (LEU282) to (PHE328) CRYSTAL STRUCTURE OF GLYCEROL KINASE IN COMPLEX WITH GLYCEROL FROM SINORHIZOBIUM MELILOTI 1021 | STRUCTURAL GENOMICS, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, GLYCEROL KINASE, TRANSFERASE
4e1t:A (PHE149) to (LYS192) X-RAY CRYSTAL STRUCTURE OF THE TRANSMEMBRANE BETA-DOMAIN FROM INVASIN FROM YERSINIA PSEUDOTUBERCULOSIS | OUTER MEMBRANE BETA BARREL, ADHESIN, INTEGRIN, CELL ADHESION
5i82:A (GLN387) to (ALA422) FIRST CRYSTAL STRUCTURE OF E.COLI BASED RECOMBINANT DIPHTHERIA TOXIN MUTANT CRM197 | DIPHTHERIA TOXIN, CRM197, CSGID, RECOMBINANT, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, TRANSFERASE
5i82:B (GLN387) to (ALA422) FIRST CRYSTAL STRUCTURE OF E.COLI BASED RECOMBINANT DIPHTHERIA TOXIN MUTANT CRM197 | DIPHTHERIA TOXIN, CRM197, CSGID, RECOMBINANT, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, TRANSFERASE
5i82:D (GLN387) to (ALA422) FIRST CRYSTAL STRUCTURE OF E.COLI BASED RECOMBINANT DIPHTHERIA TOXIN MUTANT CRM197 | DIPHTHERIA TOXIN, CRM197, CSGID, RECOMBINANT, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, TRANSFERASE
3por:A (GLY166) to (GLY204) PORIN CONFORMATION IN THE ABSENCE OF CALCIUM; REFINED STRUCTURE AT 2.5 ANGSTROMS RESOLUTION | INTEGRAL MEMBRANE PROTEIN PORIN
4e6n:B (SER24) to (ASP57) CRYSTAL STRUCTURE OF BACTERIAL PNKP-C/HEN1-N HETERODIMER | RNA REPAIR, RNA LIGASE, LIGASE-ACTIVATING, PROTEIN BINDING, TRANSFERASE
4e6n:D (SER24) to (ASP57) CRYSTAL STRUCTURE OF BACTERIAL PNKP-C/HEN1-N HETERODIMER | RNA REPAIR, RNA LIGASE, LIGASE-ACTIVATING, PROTEIN BINDING, TRANSFERASE
4e8a:A (THR7) to (ARG57) THE CRYSTAL STRUCTURE OF P38A MAP KINASE IN COMPLEX WITH PIA24 | MAP KINASE, P38, SIGNAL TRANSDUCTION, ALTERNATIVE ACTIVATION MODES, LIPID BINDING SITE, PIA, PERIFOSINE, KINASE, PHOSPHORYLATION, TRANSFERASE
3psq:B (ALA69) to (ALA129) CRYSTAL STRUCTURE OF SPY0129, A STREPTOCOCCUS PYOGENES CLASS B SORTASE INVOLVED IN PILUS BIOGENESIS | SORTASE FOLD, SORTASE, PILUS ASSEMBLY, HYDROLASE
4eje:A (ILE59) to (SER93) STRUCTURE OF THE TSG101 UEV DOMAIN IN COMPLEX WITH AN EBOLA PTAP LATE DOMAIN PEPTIDE | ALPHA AND BETA PROTEIN, UEV DOMAIN, PROTEIN TRANSPORT
3q0t:A (ASP104) to (ASP136) CRYSTAL STRUCTURE OF HUMAN DPP-IV IN COMPLEX WITHSA-(+)- METHYL2-(3- (AMINOMETHYL)-4-(2,4-DICHLOROPHENYL)-2-METHYL- 7-OXO-5H-PYRROLO[3,4- B]PYRIDIN-6(7H)-YL)ACETATE | EXOPEPTIDASE, ALPHA/BETA HYDROLASE FOLD, BETA BARREL, BETA PROPELLER, AMINOPEPTIDASE, GLYCOPROTEIN, MEMBRANE, SERINE PROTEASE, SIGNAL- ANCHOR, TRANSMEMBRANE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3q34:B (PHE34) to (GLU66) THE CRYSTAL STRUCTURE OF YCEI-LIKE FAMILY PROTEIN FROM PSEUDOMONAS SYRINGAE | STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, UNKNOWN FUNCTION
4eqv:E (LEU26) to (SER59) STRUCTURE OF SACCHAROMYCES CEREVISIAE INVERTASE | GLYCOSIDASE GH32, BETA-PROPELLER, HYDROLASE, CARBOHYDRATE/SUGAR BINDING
5ixm:E (ALA485) to (ILE528) THE LPS TRANSPORTER LPTDE FROM YERSINIA PESTIS, CORE COMPLEX | LPTD, LPTE, LIPOPOLYSACCHARIDE, TRANSPORTER, TRANSPORT PROTEIN
3qc4:A (PHE93) to (GLY158) PDK1 IN COMPLEX WITH DFG-OUT INHIBITOR XXX | SERINE/THREONINE KINASE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qdg:D (GLN140) to (SER175) THE COMPLEX BETWEEN TCR DMF5 AND HUMAN CLASS I MHC HLA-A2 WITH THE BOUND MART-1(26-35)(A27L) PEPTIDE | MART-1 PEPTIDE, DECAPEPTIDE, MHC CLASS I, HLA-A2, TCR DMF5, CROSS- REACTIVITY, MELANOMA, CANCER, IMMUNE SYSTEM
3qfx:A (GLY203) to (PRO238) TRYPANOSOMA BRUCEI DIHYDROFOLATE REDUCTASE PYRIMETHAMINE COMPLEX | PYRIMETHAMINE, ANTIFOLATE RESISTANCE, TRYPANOSOME, DIHYDROFOLATE REDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3qfx:B (GLY203) to (PRO238) TRYPANOSOMA BRUCEI DIHYDROFOLATE REDUCTASE PYRIMETHAMINE COMPLEX | PYRIMETHAMINE, ANTIFOLATE RESISTANCE, TRYPANOSOME, DIHYDROFOLATE REDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5j3z:B (SER203) to (HIS236) CRYSTAL STRUCTURE OF M2HTDP2-CAT IN COMPLEX WITH A SMALL MOLECULE INHIBITOR | TYROSYL DNA PHOSPHODIESTERASE 2 CATALYTIC DOMAIN, HYDROLASE
5j63:C (ALA231) to (GLY282) CRYSTAL STRUCTURE OF THE N-TERMINAL N-FORMYLTRANSFERASE DOMAIN (RESIDUES 1-306) OF ESCHERICHIA COLI ARNA IN COMPLEX WITH UDP-ARA4N AND FOLINIC ACID | LIPOPOLYSACCHARIDE, TRANSFERASE
4f63:B (LEU484) to (MET515) CRYSTAL STRUCTURE OF HUMAN FIBROBLAST GROWTH FACTOR RECEPTOR 1 KINASE DOMAIN IN COMPLEX WITH COMPOUND 1 | KINASE, ATP BINDING, PHOSPHORYLATION, TRANS-MEMBRANE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3qlb:A (GLY80) to (PRO157) ENANTIOPYOCHELIN OUTER MEMBRANE TONB-DEPENDENT TRANSPORTER FROM PSEUDOMONAS FLUORESCENS BOUND TO THE FERRI-ENANTIOPYOCHELIN | MEMBRANE PROTEIN, TRANSPORT, FERRI-ENANTIOPYOCHELIN, OUTER MEMBRANE, METAL TRANSPORT
4f9l:A (GLY93) to (GLY141) CRYSTAL STRUCTURE OF THE HUMAN BTN3A1 ECTODOMAIN IN COMPLEX WITH THE 20.1 SINGLE CHAIN ANTIBODY | B7 SUPERFAMILY, BUTYROPHILIN, CD277, IMMUNE SYSTEM
4ux8:A (ALA294) to (GLU332) RET RECOGNITION OF GDNF-GFRALPHA1 LIGAND BY A COMPOSITE BINDING SITE PROMOTES MEMBRANE-PROXIMAL SELF-ASSOCIATION | SIGNALING PROTEIN, VERTEBRATE DEVELOPMENT, HUMAN DISEASES, PART OF THE RET-GFL- GFRA COMPLEX
4ux8:B (ALA294) to (GLU332) RET RECOGNITION OF GDNF-GFRALPHA1 LIGAND BY A COMPOSITE BINDING SITE PROMOTES MEMBRANE-PROXIMAL SELF-ASSOCIATION | SIGNALING PROTEIN, VERTEBRATE DEVELOPMENT, HUMAN DISEASES, PART OF THE RET-GFL- GFRA COMPLEX
4ux9:D (ASN9) to (LYS56) CRYSTAL STRUCTURE OF JNK1 BOUND TO A MKK7 DOCKING MOTIF | TRANSFERASE, JNK1, INTRINSICALLY DISORDERED DOMAINS, MKK7
4fa8:B (GLY100) to (ALA150) MULTI-PRONGED MODULATION OF CYTOKINE SIGNALING | IMMUNOGLOBULIN-LIKE DOMAINS, 4-HELIX BUNDLE FOLD, VIRAL PROTEIN- CYTOKINE COMPLEX
4fa8:D (GLY100) to (ALA150) MULTI-PRONGED MODULATION OF CYTOKINE SIGNALING | IMMUNOGLOBULIN-LIKE DOMAINS, 4-HELIX BUNDLE FOLD, VIRAL PROTEIN- CYTOKINE COMPLEX
3qnb:C (THR194) to (TRP222) CRYSTAL STRUCTURE OF AN ENGINEERED OXA-10 VARIANT WITH CARBAPENEMASE ACTIVITY, OXA-10LOOP24 | ANTIBIOTIC RESISTANCE, HYDROLYSIS OF AMIDE BOND OF BETA-LACTAM COMPOUNDS, HYDROLASE
3qnb:D (THR194) to (TRP222) CRYSTAL STRUCTURE OF AN ENGINEERED OXA-10 VARIANT WITH CARBAPENEMASE ACTIVITY, OXA-10LOOP24 | ANTIBIOTIC RESISTANCE, HYDROLYSIS OF AMIDE BOND OF BETA-LACTAM COMPOUNDS, HYDROLASE
3qnc:B (THR194) to (TRP222) CRYSTAL STRUCTURE OF A RATIONALLY DESIGNED OXA-10 VARIANT SHOWING CARBAPENEMASE ACTIVITY, OXA-10LOOP48 | ANTIBIOTIC RESISTANCE, HYDROLYSIS OF AMIDE BOND OF BETA-LACTAM COMPOUNDS, HYDROLASE
4v0h:C (LEU15) to (PRO52) HUMAN METALLO BETA LACTAMASE DOMAIN CONTAINING PROTEIN 1 (HMBLAC1) | HYDROLASE, GLYOXALASE II FAMILY, NON-HEME IRON
4v0h:D (LEU15) to (PRO52) HUMAN METALLO BETA LACTAMASE DOMAIN CONTAINING PROTEIN 1 (HMBLAC1) | HYDROLASE, GLYOXALASE II FAMILY, NON-HEME IRON
3qs1:A (ASP2) to (ALA28) CRYSTAL STRUCTURE OF KNI-10006 COMPLEX OF PLASMEPSIN I (PMI) FROM PLASMODIUM FALCIPARUM | ASPARTIC PROTEASE, MALARIA, KNI, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3qsz:A (PRO138) to (PRO172) CRYSTAL STRUCTURE OF THE STAR-RELATED LIPID TRANSFER PROTEIN (FRAGMENT 25-204) FROM XANTHOMONAS AXONOPODIS AT THE RESOLUTION 2.4A, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET XAR342 | STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, STAR DOMAIN, UNKNOWN FUNCTION
4ffv:A (PRO179) to (THR229) CRYSTAL STRUCTURE OF DIPEPTIDYL PEPTIDASE IV (DPP4, DPP-IV, CD26) IN COMPLEX WITH 11A19 FAB | HYDROLASE, HYDROLASE-IMMUNE SYSTEM, INHIBITOR COMPLEX
3qw9:B (GLU41) to (ASN82) CRYSTAL STRUCTURE OF BETAGLYCAN ZP-C DOMAIN | CYTOKINE RECEPTOR, IMMUNOGLOBULIN DOMAIN, ZONA PELLUCIDA, TGF-BETA LIGAND CO-RECEPTOR, PROTEIN POLYMERIZATION
4w4y:A (GLN47) to (SER96) JNK2/3 IN COMPLEX WITH 3-(4-{[(4-METHYLPHENYL)CARBAMOYL]AMINO}-1H- PYRAZOL-1-YL)-N-(2-METHYLPYRIDIN-4-YL)BENZAMIDE | JNK, MAP KINASE, ISOFORM SELECTIVE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4frk:A (ASN5) to (ASN28) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH AMINOOXAZOLINE XANTHENE 11A | MEMBRANE PROTEIN, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, HYDROLASE- INHIBITOR COMPLEX
5jqk:A (LEU673) to (PHE709) THE XRAY CRYSTAL STRUCTURE OF P. FALCIPARUM AMINOPEPTIDASE P | AMINOPEPTIDASE, HYDROLASE
5jqk:B (LEU673) to (PHE709) THE XRAY CRYSTAL STRUCTURE OF P. FALCIPARUM AMINOPEPTIDASE P | AMINOPEPTIDASE, HYDROLASE
4fzh:A (LEU476) to (ALA504) STRUCTURE OF THE ULSTER STRAIN NEWCASTLE DISEASE VIRUS HEMAGGLUTININ- NEURAMINIDASE REVEALS AUTO-INHIBITORY INTERACTIONS ASSOCIATED WITH LOW VIRULENCE | HYDROLASE
5jw4:Q (THR131) to (VAL196) STRUCTURE OF MEDI8852 FAB FRAGMENT IN COMPLEX WITH H5 HA | ANTIBODY INFLUENZA BROADLY NEUTRALIZING, IMMUNE SYSTEM
5jzt:C (VAL197) to (THR275) CRYO-EM STRUCTURE OF AEROLYSIN PORE IN LMNG MICELLE | PORE FORMING TOXIN, CONCENTRIC BETA-BARREL, AEROLYSIN, TOXIN
5jzt:E (VAL197) to (THR275) CRYO-EM STRUCTURE OF AEROLYSIN PORE IN LMNG MICELLE | PORE FORMING TOXIN, CONCENTRIC BETA-BARREL, AEROLYSIN, TOXIN
5k8m:C (TYR261) to (TYR297) APO 5-NITROANTHRANILATE AMINOHYDROLASE | NITROAROMATICS, DEAMINASE, METALLOENZYME, HYDROLASE
4geo:A (THR7) to (LYS54) P38A MAP KINASE DEF-POCKET PENTA MUTANT (M194A, L195A, H228A, I229A, Y258A) | DOCKING SITE, SUBSTRATE SELECTIVITY, SER/THR KINASE, PHOSPHORYLATION, TRANSFERASE
5lal:A (VAL149) to (LEU183) STRUCTURE OF ARABIDOPSIS DIRIGENT PROTEIN ATDIR6 | ALL BETA, PROTEIN BINDING, PLANT PROTEIN
2ajb:C (ASP104) to (ASP136) PORCINE DIPEPTIDYL PEPTIDASE IV (CD26) IN COMPLEX WITH THE TRIPEPTIDE TERT-BUTYL-GLY-L-PRO-L-ILE (TBU-GPI) | SERINE PROTEASE, DIPEPTIDYL PEPTIDASE, ALPHA/BETA-HYDROLASE, BETA- PROPELLER, OXYANION HOLE, SUBSTRATE CHANNELING, DRUG DESIGN, DIABETES MELLITUS, FLEXIBILITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1nmt:A (HIS138) to (ASN175) N-MYRISTOYL TRANSFERASE FROM CANDIDA ALBICANS AT 2.45 A | MYRISTYLATION, ANTIFUNGAL TARGET, COA, TRANSFERASE, ACYLTRANSFERASE
1nmt:B (HIS138) to (ASN175) N-MYRISTOYL TRANSFERASE FROM CANDIDA ALBICANS AT 2.45 A | MYRISTYLATION, ANTIFUNGAL TARGET, COA, TRANSFERASE, ACYLTRANSFERASE
1nmt:C (HIS138) to (ASN175) N-MYRISTOYL TRANSFERASE FROM CANDIDA ALBICANS AT 2.45 A | MYRISTYLATION, ANTIFUNGAL TARGET, COA, TRANSFERASE, ACYLTRANSFERASE
2b0r:A (ASN162) to (VAL197) CRYSTAL STRUCTURE OF CYCLASE-ASSOCIATED PROTEIN FROM CRYPTOSPORIDIUM PARVUM | STRUCTURAL GENOMICS CONSORTIUM, CRYPTOSPORIDIUM PARVUM, CYCLASE-ASSOCIATED PROTEIN, SGC, UNKNOWN FUNCTION
4x2f:A (ILE211) to (SER235) SELECTION OF FRAGMENTS FOR KINASE INHIBITOR DESIGN: DECORATION IS KEY | TRANSFERASE, PROTEIN KINASE, INHIBITOR COMPLEX, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2bs7:1 (GLY108) to (GLN141) CRYSTAL STRUCTURE OF F17B-G IN COMPLEX WITH CHITOBIOSE | BACTERIAL ADHESIN, BACTERIAL ATTACHMENT, PATHOGENESIS, IMMUNOGLOBULIN FOLD ADHESIN, LECTIN, FIMBRIAE, PROTEIN- SUGAR COMPLEX
4x9i:A (GLY286) to (THR335) CRYSTAL STRUCTURE OF DSCAM1 ISOFORM 9.44, N-TERMINAL FOUR IG DOMAINS | IG FOLD, CELL ADHESION
3scg:C (ILE92) to (THR126) FE(II)-HPPE WITH R-HPP | CUPIN-FOLD, HYDROXYPROPYLPHOSPHONIC ACID EPOXIDASE, MONONUCLEAR NON- HEME IRON ENZYME, METAL BINDING PROTEIN
3fi2:A (TYR49) to (SER96) CRYSTAL STRUCTURE OF JNK3 WITH AMINO-PYRAZOLE INHIBITOR, SR- 3451 | JNK3, PROTEIN-INHIBITOR COMPLEX, ALTERNATIVE SPLICING, ATP- BINDING, CHROMOSOMAL REARRANGEMENT, CYTOPLASM, EPILEPSY, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3fi3:A (TYR49) to (SER96) CRYSTAL STRUCTURE OF JNK3 WITH INDAZOLE INHIBITOR, SR-3737 | JNK3, PROTEIN-INHIBITOR COMPLEX, ALTERNATIVE SPLICING, ATP- BINDING, CHROMOSOMAL REARRANGEMENT, CYTOPLASM, EPILEPSY, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
4i43:B (PRO1256) to (VAL1304) CRYSTAL STRUCTURE OF PRP8:AAR2 COMPLEX | SPLICEOSOME, U5 SNRNP, PRP8, REVERSE TRANSCRIPTASE, AAR2, ENDONUCLEASE, RNASE H, JAB1/MPN, PRE-MRNA SPLICING, SPLICING
4xkw:A (LEU663) to (GLU692) TAILSPIKE PROTEIN MUTANT D339N OF E. COLI BACTERIOPHAGE HK620 IN COMPLEX WITH PENTASACCHARIDE | BETA HELIX, PROTEIN-CARBOHYDRATE COMPLEX, PECTIN LYASE FOLD, VIRAL PROTEIN
4xkx:A (ASN5) to (ASN28) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH 2-AMINOOXAZOLINE 3- AZAXANTHENE INHIBITOR 28 | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3fsk:A (THR7) to (LEU55) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH RO6257 | P38; MAP KINASE; SERINE/THREONINE KINASE, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, SIGNALING PROTEIN
4xup:A (VAL234) to (MET270) STRUCTURE OF THE N-TERMINAL CBM22-1-CBM22-2 TANDEM DOMAIN FROM PAENIBACILLUS BARCINONENSIS XYN10C | BINDING SITE, CARBOHYDRATES, ENZYME STABILITY, SUBSTRATE SPECIFICITY, ENDO-1, 4-BETA-XYLANASE, XYLAN-BINDING DOMAIN, THERMOPHILIC ENZYMES, THERMOSTABILIZING DOMAINS, SUGAR BINDING PROTEIN
4iy9:B (ALA89) to (GLY117) BMLP3 - C2 CRYSTAL FORM | LIPOPROTEIN 11 FAMILY, HEMOLYMPH, LIPID BINDING PROTEIN
4iyc:A (SER132) to (GLY157) STRUCTURE OF THE T244A MUTANT OF THE PANTON-VALENTINE LEUCOCIDIN COMPONENT FROM STAPHYLOCOCCUS AUREUS | STAPHYLOCOCCUS AUREUS, S COMPONENT LEUCOCIDIN, BI-COMPONENT LEUCOTOXIN, BETA-BARREL PORE FORMING TOXIN, TOXIN
4iyc:D (SER132) to (GLY157) STRUCTURE OF THE T244A MUTANT OF THE PANTON-VALENTINE LEUCOCIDIN COMPONENT FROM STAPHYLOCOCCUS AUREUS | STAPHYLOCOCCUS AUREUS, S COMPONENT LEUCOCIDIN, BI-COMPONENT LEUCOTOXIN, BETA-BARREL PORE FORMING TOXIN, TOXIN
2qx2:A (ASN167) to (ASP213) STRUCTURE OF THE C-TERMINAL DOMAIN OF SEX PHEROMONE STAPH-CAM373 PRECURSOR FROM STAPHYLOCOCCUS AUREUS | STAPHYLOCOCCUS AUREUS, SEX PHEROMONE STAPH-CAM373 PRECURSOR, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
4jdo:F (GLY146) to (GLU185) SECRETED CHLAMYDIAL PROTEIN PGP3, COILED-COIL DELETION | VIRULENCE FACTOR, SECRETED PROTEIN, CHLAMYDIA, INFLAMMATORY RESPONSE, TNF, CELL INVASION
4jdo:I (GLY146) to (GLU185) SECRETED CHLAMYDIAL PROTEIN PGP3, COILED-COIL DELETION | VIRULENCE FACTOR, SECRETED PROTEIN, CHLAMYDIA, INFLAMMATORY RESPONSE, TNF, CELL INVASION
2dup:A (GLY244) to (GLN275) CRYSTAL STRUCTURE OF VIP36 EXOPLASMIC/LUMENAL DOMAIN, METAL-FREE FORM | BETA SANDWICH, CARBOHYDRATE BINDING PROTEIN, CARGO RECEPTOR, PROTEIN TRANSPORT
2dup:B (GLY244) to (GLN275) CRYSTAL STRUCTURE OF VIP36 EXOPLASMIC/LUMENAL DOMAIN, METAL-FREE FORM | BETA SANDWICH, CARBOHYDRATE BINDING PROTEIN, CARGO RECEPTOR, PROTEIN TRANSPORT
3tqy:B (ASP20) to (ASN64) STRUCTURE OF A SINGLE-STRANDED DNA-BINDING PROTEIN (SSB), FROM COXIELLA BURNETII | DNA REPLICATION, TRANSFERASE
1qqc:A (ILE54) to (THR88) CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK | DNA POLYMERASE, THERMOSTABLE, EXONUCLEASE, RBD DOMAIN, TRANSFERASE
3u33:B (TRP215) to (PRO241) CRYSTAL STRUCTURE OF THE E. COLI ADAPTIVE RESPONSE PROTEIN AIDB IN THE SPACE GROUP P3(2) | ACYL-COENZYME A DEHYDROGENASE, PROTECTIVE FUNCTION IN THE PRESENCE OF ALKYLATING AGENTS, DNA BINDING, FAD BINDING, OXIDOREDUCTASE
3u33:F (TRP215) to (PRO241) CRYSTAL STRUCTURE OF THE E. COLI ADAPTIVE RESPONSE PROTEIN AIDB IN THE SPACE GROUP P3(2) | ACYL-COENZYME A DEHYDROGENASE, PROTECTIVE FUNCTION IN THE PRESENCE OF ALKYLATING AGENTS, DNA BINDING, FAD BINDING, OXIDOREDUCTASE
3u33:H (TRP215) to (PRO241) CRYSTAL STRUCTURE OF THE E. COLI ADAPTIVE RESPONSE PROTEIN AIDB IN THE SPACE GROUP P3(2) | ACYL-COENZYME A DEHYDROGENASE, PROTECTIVE FUNCTION IN THE PRESENCE OF ALKYLATING AGENTS, DNA BINDING, FAD BINDING, OXIDOREDUCTASE
3u33:L (TRP215) to (PRO241) CRYSTAL STRUCTURE OF THE E. COLI ADAPTIVE RESPONSE PROTEIN AIDB IN THE SPACE GROUP P3(2) | ACYL-COENZYME A DEHYDROGENASE, PROTECTIVE FUNCTION IN THE PRESENCE OF ALKYLATING AGENTS, DNA BINDING, FAD BINDING, OXIDOREDUCTASE
3u3v:A (GLU104) to (PRO146) THE S-SAD PHASED CRYSTAL STRUCTURE OF THE ECTO-DOMAIN OF DEATH RECEPTOR 6 (DR6) | TRIGGER APOPTOSIS, APOPTOSIS
1fce:A (ILE449) to (ASN490) PROCESSIVE ENDOCELLULASE CELF OF CLOSTRIDIUM CELLULOLYTICUM | CELLULASE DEGRADATION, FAMILY 48, THIOOLIGOSACCHARIDE INHIBITOR, PROCESSIVE ENDO ACTION, HYDROLASE
1fgt:A (SER111) to (PHE144) LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q697N MUTANT | DIOXYGENASE, LIPOXYGENASE, METALLOPROTEIN, FATTY ACIDS, OXIDOREDUCTASE
4yu6:B (GLY457) to (GLY501) CRYSTAL STRUCTURE OF BACILLUS ANTHRACIS IMMUNE INHIBITOR A2 PEPTIDASE ZYMOGEN | HYDROLASE, METALLOPEPTIDASE, METZINCIN
2vf1:A (ASN257) to (ASP295) X-RAY CRYSTALLOGRAPHIC STRUCTURE OF THE PICOBIRNAVIRUS CAPSID | DSRNA VIRUS STRUCTURE, VIRAL PROTEIN, PICOBIRNAVIRUS, CAPSID PROTEIN, TRIACONTAHEDRON, VIRUS
2vf1:B (ASN257) to (ASP295) X-RAY CRYSTALLOGRAPHIC STRUCTURE OF THE PICOBIRNAVIRUS CAPSID | DSRNA VIRUS STRUCTURE, VIRAL PROTEIN, PICOBIRNAVIRUS, CAPSID PROTEIN, TRIACONTAHEDRON, VIRUS
1g8j:A (ALA14) to (VAL86) CRYSTAL STRUCTURE ANALYSIS OF ARSENITE OXIDASE FROM ALCALIGENES FAECALIS | OXIDASE, ARSENITE, MOLYBDOPTERIN, [3FE-4S] CLUSTER, [2FE- 2S] CLUSTER, RIESKE, OXIDOREDUCTASE
1g8j:C (ALA14) to (VAL86) CRYSTAL STRUCTURE ANALYSIS OF ARSENITE OXIDASE FROM ALCALIGENES FAECALIS | OXIDASE, ARSENITE, MOLYBDOPTERIN, [3FE-4S] CLUSTER, [2FE- 2S] CLUSTER, RIESKE, OXIDOREDUCTASE
3uvp:A (THR7) to (LEU55) HUMAN P38 MAP KINASE IN COMPLEX WITH A BENZAMIDE SUBSTITUTED BENZOSUBERONE | PROTEIN KINASE, SELECTIVE P38 INHIBITOR, SAR, BENZOSUBERON DERIVATIVE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3hv6:A (THR7) to (LYS54) HUMAN P38 MAP KINASE IN COMPLEX WITH RL39 | DFG-OUT, TYPE II, RL39, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3hx6:B (ALA924) to (ASP966) CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA PILY1 C-TERMINAL DOMAIN | BETA PROPELLER, PILUS PROTEIN, CELL ADHESION
4kou:A (SER52) to (ALA84) CRYSTAL STRUCTURE OF A GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794 IN COMPLEX WITH CEFIXIME | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, TRANSFERASE
3hz3:A (VAL1294) to (ASN1323) LACTOBACILLUS REUTERI N-TERMINALLY TRUNCATED GLUCANSUCRASE GTF180(D1025N)-SUCROSE COMPLEX | PROTEIN-SUCROSE COMPLEX, MULTIDOMAIN PROTEIN, GLYCOSYLTRANSFERASE, TRANSFERASE
1sgk:A (GLN387) to (ALA422) NUCLEOTIDE-FREE DIPHTHERIA TOXIN | TOXIN, ADP-RIBOSYLATION, TRANSFERASE, GLYCOSYLTRANSFERASE, NAD, ADP- RIBOSYL TRANSFERASE
2vy8:A (SER634) to (LEU668) THE 627-DOMAIN FROM INFLUENZA A VIRUS POLYMERASE PB2 SUBUNIT WITH GLU-627 | VIRAL PROTEIN, TRANSCRIPTION, MRNA CAPPING, MITOCHONDRION, MRNA PROCESSING
4l7h:A (TYR342) to (ALA368) DIETHYLAMINOSULFUR TRIFLUORIDE-MEDIATED INTRAMOLECULAR CYCLIZATION OF 2-HYDROXY-BENZYLUREAS TO FUSED BICYCLIC AMINOOXAZOLINE COMPOUNDS AND EVALUATION OF THEIR BIOCHEMICAL ACTIVITY AGAINST BETA-SECRETASE-1 (BACE-1) | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4lhn:A (THR137) to (GLY168) STRUCTURE OF THE N-TERMINAL DOMAIN OF THE FLO1 ADHESIN (N-FLO1P) FROM THE YEAST SACCHAROMYCES CEREVISIAE, IN COMPLEX WITH CALCIUM AND MANNOSE | PA14 DOMAIN, CELL ADHESION
1tkr:A (PRO181) to (ASP230) HUMAN DIPEPTIDYL PEPTIDASE IV/CD26 INHIBITED WITH DIISOPROPYL FLUOROPHOSPHATE | ALPHA/BETA HYDROLASE, BETA-PROPELLER, HOMODIMER, HYDROLASE
1hkq:A (ARG78) to (GLY110) PPS10 PLASMID DNA REPLICATION INITIATOR PROTEIN REPA. REPLICATION INACTIVE, DIMERIC N-TERMINAL DOMAIN. | DNA BINDING PROTEIN, WINGED-HELIX, PPS10 PLASMID, REPLICATION INITIATOR DIMER.
2wbi:A (GLY182) to (ASN223) CRYSTAL STRUCTURE OF HUMAN ACYL-COA DEHYDROGENASE 11 | HUMAN, ACYL-COA, DEHYDROGENASE, PHOSPHOPROTEIN, OXIDOREDUCTASE
4zxn:A (ASP225) to (ALA263) CRYSTAL STRUCTURE OF RAT CORONAVIRUS STRAIN NEW-JERSEY HEMAGGLUTININ- ESTERASE | HEMAGGLUTININS, CORONAVIRUS, VIRAL PROTEIN
2i03:A (PRO181) to (ASP230) CRYSTAL STRUCTURE OF HUMAN DIPEPTIDYL PEPTIDASE 4 (DPP IV) WITH POTENT ALKYNYL CYANOPYRROLIDINE (ABT-279) | ENZYME, SERINE PEPTIDASE, HYDROLASE
2i03:B (PRO181) to (ASP230) CRYSTAL STRUCTURE OF HUMAN DIPEPTIDYL PEPTIDASE 4 (DPP IV) WITH POTENT ALKYNYL CYANOPYRROLIDINE (ABT-279) | ENZYME, SERINE PEPTIDASE, HYDROLASE
2i03:C (PRO181) to (ASP230) CRYSTAL STRUCTURE OF HUMAN DIPEPTIDYL PEPTIDASE 4 (DPP IV) WITH POTENT ALKYNYL CYANOPYRROLIDINE (ABT-279) | ENZYME, SERINE PEPTIDASE, HYDROLASE
1ifr:A (HIS434) to (ASN456) STRUCTURE OF LAMIN A/C GLOBULAR DOMAIN | IMMUNOGLOBULIN, IMMUNE SYSTEM
1uk4:A (GLY146) to (THR175) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) COMPLEXED WITH AN INHIBITOR | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, AN INHIBITOR, HYDROLASE
1urx:A (VAL120) to (ILE150) CRYSTALLOGRAPHIC STRUCTURE OF BETA-AGARASE A IN COMPLEX WITH OLIGOAGAROSE | HYDROLASE, BETA-AGARASE, AGAROSE, GLYCOSIDE HYDROLASE, FAMILY 16, DOUBLE HELIX, TWO BINDING-SITES
1iyl:A (HIS138) to (HIS180) CRYSTAL STRUCTURE OF CANDIDA ALBICANS N-MYRISTOYLTRANSFERASE WITH NON- PEPTIDIC INHIBITOR | TRANSFERASE
2x6x:A (LEU663) to (GLU692) TAILSPIKE PROTEIN MUTANT D339N OF E.COLI BACTERIOPHAGE HK620 IN COMPLEX WITH HEXASACCHARIDE | HYDROLASE, VIRAL PROTEIN
5aos:A (TRP490) to (HIS511) STRUCTURE OF A NOVEL CARBOHYDRATE BINDING MODULE FROM RUMINOCOCCUS FLAVEFACIENS FD-1 ENDOGLUCANASE CEL5A SOLVED AT THE AS EDGE | SUGAR BINDING PROTEIN, CARBOHYDRATE BINDING MODULE, ENDOGLUCANASE CEL5A, CELLULOSOME, RUMINOCOCCUS FLAVEFACIENS FD-1, CARBOHYDRATE ACTIVE ENZYME
2xhb:A (ILE54) to (THR88) CRYSTAL STRUCTURE OF DNA POLYMERASE FROM THERMOCOCCUS GORGONARIUS IN COMPLEX WITH HYPOXANTHINE-CONTAINING DNA | TRANSFERASE-DNA COMPLEX, REPLICATION, EXONUCLEASE, DNA DAMAGE, EXO MINUS
3wxk:C (ALA270) to (ALA318) CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI GAMBIENSE GLYCEROL KINASE IN COMPLEX WITH GLYCEROL | TRYPANOSOMA, GLYCEROL KINASE, SUGAR KINASE SUPERFAMILY, TRANSFERASE, GLYCOSOME
3wz5:D (ALA143) to (ARG187) STRUCTURE OF THE PERIPLASMIC DOMAIN OF DOTI (CRYSTAL FORM II) | TYPE IVB SECRETION, UNKNOWN FUNCTION
3znt:A (LYS208) to (LEU232) CRYSTAL STRUCTURE OF OXA-24 CLASS D BETA-LACTAMASE WITH TAZOBACTAM | HYDROLASE
1kfg:A (ASN519) to (LEU547) THE X-RAY CRYSTAL STRUCTURE OF CEL9G FROM CLOSTRIDIUM CELLULOLYTICUM COMPLEXED WITH A THIO-OLIGOSACCHARIDE INHIBITOR | ENDOGLUCANASE, FAMILY 9, THIO-OLIGOSACCHARIDE, CELLULOSE BINDING DOMAIN, (ALPHA-ALPHA)6-BARREL, HYDROLASE
1kfg:B (ASN519) to (LEU547) THE X-RAY CRYSTAL STRUCTURE OF CEL9G FROM CLOSTRIDIUM CELLULOLYTICUM COMPLEXED WITH A THIO-OLIGOSACCHARIDE INHIBITOR | ENDOGLUCANASE, FAMILY 9, THIO-OLIGOSACCHARIDE, CELLULOSE BINDING DOMAIN, (ALPHA-ALPHA)6-BARREL, HYDROLASE
3zs5:A (THR7) to (LYS54) STRUCTURAL BASIS FOR KINASE SELECTIVITY OF THREE CLINICAL P38ALPHA INHIBITORS | TRANSFERASE, TAK-715, SCIO-469, VX-745, SB-203580
2m9p:A (ALA117) to (GLY141) NMR STRUCTURE OF AN INHIBITOR BOUND DENGUE NS3 PROTEASE | NS2B COFACTOR, COVALENT LIGAND, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2mf0:A (GLU10) to (ALA36) STRUCTURAL BASIS OF THE NON-CODING RNA RSMZ ACTING AS PROTEIN SPONGE: CONFORMER L OF RSMZ(1-72)/RSME(DIMER) 1TO3 COMPLEX | PROTEIN/RNA, NON-CODING RNA, TRANSLATION REPRESSOR PROTEIN, PSEUDOMONAS AERUGINOSA, MESSENGER RNA, PROTEIN SEQUESTRATION, TWO CONFORMATIONS, RNASE E CLEAVE SITES, HOMO-DIMERIC PROTEINS, COOPERATIVITY, MULTIPLE PROTEIN BINDING SITES, TRANSLATION ACTIVATION, RIBOSOME BINDING SITE, LARGE SOLUTION STRUCTURE, ELECTRON PARAMAGNETIC RESONANCE, PROTEIN SPONGE, RNP ASSEMBLY, RNA BINDING PROTEIN-RNA COMPLEX
2mf0:C (GLU10) to (ALA36) STRUCTURAL BASIS OF THE NON-CODING RNA RSMZ ACTING AS PROTEIN SPONGE: CONFORMER L OF RSMZ(1-72)/RSME(DIMER) 1TO3 COMPLEX | PROTEIN/RNA, NON-CODING RNA, TRANSLATION REPRESSOR PROTEIN, PSEUDOMONAS AERUGINOSA, MESSENGER RNA, PROTEIN SEQUESTRATION, TWO CONFORMATIONS, RNASE E CLEAVE SITES, HOMO-DIMERIC PROTEINS, COOPERATIVITY, MULTIPLE PROTEIN BINDING SITES, TRANSLATION ACTIVATION, RIBOSOME BINDING SITE, LARGE SOLUTION STRUCTURE, ELECTRON PARAMAGNETIC RESONANCE, PROTEIN SPONGE, RNP ASSEMBLY, RNA BINDING PROTEIN-RNA COMPLEX
5c7g:A (LYS125) to (GLY151) CRYSTAL STRUCTURE OF THE B1 DOMAIN OF HUMAN NEUROPILIN-1 IN COMPLEX WITH A BICINE MOLECULE | NEUROPILIN-1, HUMAN, BLOOD COAGULATION FACTORS, CELL ADHESION, BINDING SITES, PROTEIN BINDING
1xkz:B (ILE515) to (PHE541) CRYSTAL STRUCTURE OF THE ACYLATED BETA-LACTAM SENSOR DOMAIN OF BLAR1 FROM S. AUREUS | BETA-LACTAM RECEPTOR, SIGNAL TRANSDUCTION, SIGNALING PROTEIN
4acx:A (TYR342) to (ALA368) AMINOIMIDAZOLES AS BACE-1 INHIBITORS. X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 23 | HYDROLASE, ALZHEIMER'S DISEASE
4p2b:A (GLY419) to (GLN453) CRYSTAL STRUCTURE OF THE APO FORM OF THE GLUTAMINYL-TRNA SYNTHETASE CATALYTIC DOMAIN FROM TOXOPLASMA GONDII. | AMINOACYL TRNA SYNTHETASE, LIGASE
5d41:A (GLY719) to (LEU747) EGFR KINASE DOMAIN IN COMPLEX WITH MUTANT SELECTIVE ALLOSTERIC INHIBITOR | ALLOSTERIC INHIBITOR, EGFR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1yew:A (THR303) to (ASP326) CRYSTAL STRUCTURE OF PARTICULATE METHANE MONOOXYGENASE | MEMBRANE PROTEIN, METHANE, BETA BARREL, OXIDOREDUCTASE
1yew:E (THR303) to (ASP326) CRYSTAL STRUCTURE OF PARTICULATE METHANE MONOOXYGENASE | MEMBRANE PROTEIN, METHANE, BETA BARREL, OXIDOREDUCTASE
1yew:I (THR303) to (ASP326) CRYSTAL STRUCTURE OF PARTICULATE METHANE MONOOXYGENASE | MEMBRANE PROTEIN, METHANE, BETA BARREL, OXIDOREDUCTASE
1n1m:A (PRO181) to (ASP230) HUMAN DIPEPTIDYL PEPTIDASE IV/CD26 IN COMPLEX WITH AN INHIBITOR | ALPHA/BETA, BETA-PROPELLER, DIMER, HYDROLASE
3ac0:A (PHE714) to (GLY747) CRYSTAL STRUCTURE OF BETA-GLUCOSIDASE FROM KLUYVEROMYCES MARXIANUS IN COMPLEX WITH GLUCOSE | GLYCOSIDE HYDROLASE FAMILY3 BETA-GLUCOSIDASE, PA14 DOMAIN, HYDROLASE
3ac0:B (PHE714) to (GLY747) CRYSTAL STRUCTURE OF BETA-GLUCOSIDASE FROM KLUYVEROMYCES MARXIANUS IN COMPLEX WITH GLUCOSE | GLYCOSIDE HYDROLASE FAMILY3 BETA-GLUCOSIDASE, PA14 DOMAIN, HYDROLASE
3ac0:D (PHE714) to (GLY747) CRYSTAL STRUCTURE OF BETA-GLUCOSIDASE FROM KLUYVEROMYCES MARXIANUS IN COMPLEX WITH GLUCOSE | GLYCOSIDE HYDROLASE FAMILY3 BETA-GLUCOSIDASE, PA14 DOMAIN, HYDROLASE
5dfv:F (VAL562) to (TYR651) CRYSTAL STRUCTURE OF HUMAN CD81 LARGE EXTRACELLULAR LOOP IN COMPLEX WITH MURINE FAB FRAGMENT K04 | HELICAL BUNDLE, CELL ADHESION, ANTIBODY-ANTIGEN COMPLEX, IMMUNE SYSTEM
5dm7:U (VAL14) to (VAL60) CRYSTAL STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH HYGROMYCIN A | PROTEIN SYNTHESIS, PEPTIDYLTRANSFERASE, ANTIBIOTIC, AMINOCYCLITOL, RIBOSOME
3l8q:A (ALA114) to (ASN166) STRUCTURE ANALYSIS OF THE TYPE II COHESIN DYAD FROM THE ADAPTOR SCAA SCAFFOLDIN OF ACETIVIBRIO CELLULOLYTICUS | DOCKERIN-BINDING MODULE, PROTEIN-PROTEIN INTERACTIONS, LINKER SEGMENT, SCAFFOLDIN ARRANGEMENT, BETA SANDWICH, ALPHA HELIX, BETA FLAPS, STRUCTURAL PROTEIN, PROTEIN BINDING
3l8q:C (GLY281) to (GLN331) STRUCTURE ANALYSIS OF THE TYPE II COHESIN DYAD FROM THE ADAPTOR SCAA SCAFFOLDIN OF ACETIVIBRIO CELLULOLYTICUS | DOCKERIN-BINDING MODULE, PROTEIN-PROTEIN INTERACTIONS, LINKER SEGMENT, SCAFFOLDIN ARRANGEMENT, BETA SANDWICH, ALPHA HELIX, BETA FLAPS, STRUCTURAL PROTEIN, PROTEIN BINDING
4q1v:A (GLY362) to (ASN410) CRYSTAL STRUCTURE OF A PUTATIVE DIPEPTIDYL AMINOPEPTIDASE IV (BACOVA_01349) FROM BACTEROIDES OVATUS ATCC 8483 AT 2.48 A RESOLUTION | TWO DOMAIN PROTEIN, DIPEPTIDYL-PEPTIDASE IV FAMILY (PF00930), PROLYL OLIGOPEPTIDASE FAMILY (PF00326), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, HYDROLASE
3lxu:X (TYR764) to (LEU806) CRYSTAL STRUCTURE OF TRIPEPTIDYL PEPTIDASE 2 (TPP II) | SPINDLE COMPLEX, AMINOPEPTIDASE, HYDROLASE, PHOSPHOPROTEIN, SERINE PROTEASE
5eg7:A (THR329) to (GLY359) THE CAP BINDING SITE OF INFLUENZA VIRUS PROTEIN PB2 AS A DRUG TARGET | PB2 CAP, VIRAL PROTEIN
3bj7:B (TYR52) to (MET97) SPERMINE/SPERMIDINE N1-ACETYLTRANSFERASE FROM MOUSE: CRYSTAL STRUCTURE OF A TERNARY COMPLEX REVEALS SOLVENT-MEDIATED SPERMINE BINDING | SSAT, COENZYME A, ACYLTRANSFERASE, CYTOPLASM, TRANSFERASE
4rcd:A (ASN5) to (ASN28) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH A 2-AMINOOXAZOLINE 4- AZAXANTHENE INHIBITOR | ASPARTYL PROTEASE, ALZHEIMER'S DISEASE, APP, AMYLOID PRECURSOR PROTEIN, BRAIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ngc:X (GLY298) to (THR327) COMPLEX OF 6-HYDROXY-L-NICOTINE OXIDASE WITH INTERMEDIATE METHYLMYOSMINE PRODUCT FORMED DURING CATALYTIC TURNOVER | ENANTHIOMERIC SUBSTRATE-INHIBITOR, FLAVOENZYMES, NICOTINE DEGRADATION, OXIDOREDUCTASE
4cbz:A (SER41) to (PRO100) NOTCH LIGAND, JAGGED-1, CONTAINS AN N-TERMINAL C2 DOMAIN | SIGNALING PROTEIN, SIGNALLING, GLYCOPROTEIN, EXTRACELLULAR, DEVELOPMENTAL PROTEIN, NOTCH SIGNALING PATHWAY, EGF-LIKE DOMAIN TRANSMEMBRANE, EGF-LIKE DOMAIN, DISEASE MUTATION
3nsh:B (ASN11) to (THR39) BACE-1 IN COMPLEX WITH ELN475957 | MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2, MEMAPSIN-2, ASPARTYL PROTEASE 2, ASP 2, ASP2, BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1, BETA-SITE APP CLEAVING ENZYME 1, HYDROLASE
3d23:C (GLY149) to (THR175) MAIN PROTEASE OF HCOV-HKU1 | MAIN PROTEASE, ATP-BINDING, ENDONUCLEASE, EXONUCLEASE, HELICASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC-FINGER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ody:X (THR7) to (LYS54) CRYSTAL STRUCTURE OF P38ALPHA Y323Q ACTIVE MUTANT | KINASE FOLD, KINASE, PHOSPJORYLATION, TRANSFERASE
5h8k:J (GLY221) to (ASP254) CRYSTAL STRUCTURE OF MEDICAGO TRUNCATULA N-CARBAMOYLPUTRESCINE AMIDOHYDROLASE (MTCPA) C158S MUTANT | AMIDASE, HELICAL OCTAMER, ALPHA-BETA-BETA-ALPHA SANDWICH FOLD, HYDROLASE
5h8k:P (GLY221) to (ASP254) CRYSTAL STRUCTURE OF MEDICAGO TRUNCATULA N-CARBAMOYLPUTRESCINE AMIDOHYDROLASE (MTCPA) C158S MUTANT | AMIDASE, HELICAL OCTAMER, ALPHA-BETA-BETA-ALPHA SANDWICH FOLD, HYDROLASE
3duu:A (SER26) to (TRP50) CRYSTAL STRUCTURE OF SAG506-01, ORTHORHOMBIC, TWINNED, CRYSTAL 2 | ANTIBODY, KDO, TWINNING, PSEUDO-SYMMETRY, IMMUNE SYSTEM
4dcu:A (THR372) to (PHE398) CRYSTAL STRUCTURE OF B. SUBTILIS ENGA IN COMPLEX WITH GDP | GTPASE, ENGA, GDP, PROTEIN BINDING, HYDROLASE
3pag:A (ILE207) to (LEU232) CRYSTAL STRUCTURE OF THE V130D MUTANT OF OXA-24/40 IN COMPLEX WITH DORIPENEM | HYDROLASE, CARBAPENEMASE, HYDROLASE-ANTIBIOTIC COMPLEX
3pag:B (ILE207) to (LEU232) CRYSTAL STRUCTURE OF THE V130D MUTANT OF OXA-24/40 IN COMPLEX WITH DORIPENEM | HYDROLASE, CARBAPENEMASE, HYDROLASE-ANTIBIOTIC COMPLEX
5i9w:A (ILE619) to (LYS649) CRYSTAL STRUCTURE OF EPHRIN A2 (EPHA2) RECEPTOR PROTEIN KINASE WITH ANP | TRANSFERASE, TYROSINE-PROTEIN KINASE, RECEPTOR, ATP-BINDING
5ie1:A (ASN5) to (ASN28) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH 3-(2-AMINO-6-(O-TOLYL) QUINOLIN-3-YL)-N-(3,3-DIMETHYLBUTYL)PROPANAMIDE | ASPARTIC PROTEASE, ALZHEIMER'S DISEASE, APP, AMYLOID PRECURSOR PROTEIN, HYDROLASE
4exg:A (ASN53) to (ASN76) DESIGN AND SYNTHESIS OF POTENT HYDROXYETHYLAMINE (HEA) BACE-1 INHIBITORS | BACE, BETA-SECRETASE, STATINE, INHIBITOR, ASPARTYL PROTEASE, GLYCOPROTEIN, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3rg9:A (GLY203) to (PRO238) TRYPANOSOMA BRUCEI DIHYDROFOLATE REDUCTASE (TBDHFR) IN COMPLEX WITH WR99210 | TRYPANOSOMA BRUCEI, OXIDOREDUCTASE, DIHYDROFOLATE REDUCTASE, WR99210, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3rg9:B (GLY203) to (PRO238) TRYPANOSOMA BRUCEI DIHYDROFOLATE REDUCTASE (TBDHFR) IN COMPLEX WITH WR99210 | TRYPANOSOMA BRUCEI, OXIDOREDUCTASE, DIHYDROFOLATE REDUCTASE, WR99210, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5k8n:A (TYR261) to (TYR297) 5NAA-BOUND 5-NITROANTHRANILATE AMINOHYDROLASE | NITROAROMATICS, DEAMINASE, METALLOENZYME, HYDROLASE
5k8n:B (TYR261) to (TYR297) 5NAA-BOUND 5-NITROANTHRANILATE AMINOHYDROLASE | NITROAROMATICS, DEAMINASE, METALLOENZYME, HYDROLASE
5k8n:C (TYR261) to (TYR297) 5NAA-BOUND 5-NITROANTHRANILATE AMINOHYDROLASE | NITROAROMATICS, DEAMINASE, METALLOENZYME, HYDROLASE
5k8n:D (TYR261) to (TYR297) 5NAA-BOUND 5-NITROANTHRANILATE AMINOHYDROLASE | NITROAROMATICS, DEAMINASE, METALLOENZYME, HYDROLASE
5k8n:F (TYR261) to (TYR297) 5NAA-BOUND 5-NITROANTHRANILATE AMINOHYDROLASE | NITROAROMATICS, DEAMINASE, METALLOENZYME, HYDROLASE
5k8n:H (TYR261) to (TYR297) 5NAA-BOUND 5-NITROANTHRANILATE AMINOHYDROLASE | NITROAROMATICS, DEAMINASE, METALLOENZYME, HYDROLASE
5kqf:A (ASN53) to (ASN76) (4~{S},6~{S})-4-[2,4-BIS(FLUORANYL)PHENYL]-4-METHYL-6-PYRIMIDIN-5-YL- 5,6-DIHYDRO-1,3-THIAZIN-2-AMINE (COMPOUND 12) BOUND TO BACE1 | BACE-1, SMALL MOLECULE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX