4gwp:E (GLU212) to (GLN245) STRUCTURE OF THE MEDIATOR HEAD MODULE FROM S. CEREVISIAE | BINDING SITES, MEDIATOR COMPLEX, MODELS, MOLECULAR, PHOSPHORYLATION, PROTEIN STRUCTURE, TERTIARY, PROTEIN SUBUNITS, RNA POLYMERASE II, SACCHAROMYCES CEREVISIAE, STRUCTURE-ACTIVITY RELATIONSHIP, TRANSCRIPTION
2b0t:A (ASP192) to (THR223) STRUCTURE OF MONOMERIC NADP ISOCITRATE DEHYDROGENASE | MONOMERIC, NADP, IDH, OXIDOREDUCTASE
3eii:A (GLN73) to (PRO112) ZINC-BOUND GLYCOSIDE HYDROLASE 61 E FROM THIELAVIA TERRESTRIS | BETA SANDWICH, METAL BINDING SITE, FIBRONECTIN TYPE III, UNKNOWN FUNCTION
3eii:C (GLN73) to (PRO112) ZINC-BOUND GLYCOSIDE HYDROLASE 61 E FROM THIELAVIA TERRESTRIS | BETA SANDWICH, METAL BINDING SITE, FIBRONECTIN TYPE III, UNKNOWN FUNCTION
3eii:D (GLN73) to (PRO112) ZINC-BOUND GLYCOSIDE HYDROLASE 61 E FROM THIELAVIA TERRESTRIS | BETA SANDWICH, METAL BINDING SITE, FIBRONECTIN TYPE III, UNKNOWN FUNCTION
1nqf:A (ASP515) to (ASN567) OUTER MEMBRANE COBALAMIN TRANSPORTER (BTUB) FROM E. COLI, METHIONINE SUBSTIUTION CONSTRUCT FOR SE-MET SAD PHASING | BETA BARREL, COBALAMIN, VITAMIN B12, OUTER MEMBRANE TRANSPORT, TRANSPORT PROTEIN
3eja:A (GLN73) to (PRO112) MAGNESIUM-BOUND GLYCOSIDE HYDROLASE 61 ISOFORM E FROM THIELAVIA TERRESTRIS | BETA SANDWICH, FIBRONECTIN TYPE III FOLD, METAL SITE, MAGNESIUM, UNKNOWN FUNCTION
3ejp:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH 5-SUBSTITUTED SWAINSONINE ANALOG: (5R)-5-[2'-OXO-2'-(PHENYL)ETHYL]-SWAINSONINE | GH38 GLYCOSIDASE, GLYCOSIDASE, GOLGI APPARATUS, HYDROLASE, MEMBRANE, METAL-BINDING, SIGNAL-ANCHOR, TRANSMEMBRANE
3ejq:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH 5-SUBSTITUED SWAINSONINE ANALOG: (5R)-5-[2'-OXO-2'-(4-METHYLPHENYL)ETHYL]-SWAINSONINE | GH38 GLYCOSIDASE, GLYCOSIDASE, GOLGI APPARATUS, HYDROLASE, MEMBRANE, METAL-BINDING, SIGNAL-ANCHOR, TRANSMEMBRANE
3ejr:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH 5-SUBSTITUED SWAINSONINE ANALOG: (5R)-5-[2'-OXO-2'-(4-TERT-BUTYLPHENYL)ETHYL]-SWAINSONINE | GH38 GLYCOSIDASE, GLYCOSIDASE, GOLGI APPARATUS, HYDROLASE, MEMBRANE, METAL-BINDING, SIGNAL-ANCHOR, TRANSMEMBRANE
3ejs:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH 5-SUBSTITUTED SWAINSONINE ANALOG: (5S)-5-[2'-(4-TERT-BUTYLPHENYL)ETHYL]-SWAINSONINE | GH38 GLYCOSIDASE, GLYCOSIDASE, GOLGI APPARATUS, HYDROLASE, MEMBRANE, METAL-BINDING, SIGNAL-ANCHOR, TRANSMEMBRANE
3ejt:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH 5-SUBSTITUTED SWAINSONINE ANALOG:(5R)-5-[2'-(4-TERT-BUTYLPHENYL)ETHYL]-SWAINSONINE | GH38 GLYCOSIDASE, GLYCOSIDASE, GOLGI APPARATUS, HYDROLASE, MEMBRANE, METAL-BINDING, SIGNAL-ANCHOR, TRANSMEMBRANE
3eju:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH 5-SUBSTITUTED SWAINSONINE ANALOG:(5S)-5-[2'-OXO-2'-(4-TERT-BUTYLPHENYL)ETHYL]-SWAINSONINE | GH38 GLYCOSIDASE, GLYCOSIDASE, GOLGI APPARATUS, HYDROLASE, MEMBRANE, METAL-BINDING, SIGNAL-ANCHOR, TRANSMEMBRANE
2ow7:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH (1R,6S,7R,8S)-1- THIONIABICYCLO[4.3.0]NONAN-7,8-DIOL CHLORIDE | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
2p0w:A (ARG198) to (VAL238) HUMAN HISTONE ACETYLTRANSFERASE 1 (HAT1) | HAT1, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
2p0w:B (ARG198) to (VAL238) HUMAN HISTONE ACETYLTRANSFERASE 1 (HAT1) | HAT1, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
1nxm:A (LEU10) to (GLU38) THE HIGH RESOLUTION STRUCTURES OF RMLC FROM STREPTOCOCCUS SUIS | JELLY ROLL-LIKE STRUCTURE; BETA SHEET, ISOMERASE
4wve:A (GLU564) to (ILE614) CRYSTAL STRUCTURE OF THE STAPHYLOCOCCUS AUREUS SASG G52-E2-G53 MODULE | SINGLE-LAYER BETA SHEET, BIOFILM FORMATION, SURFACE, STRUCTURAL PROTEIN
3eqq:A (PRO78) to (ASP124) APO TOLUENE 2,3-DIOXYGENASE | RIESKE IRON SULFUR BINDING PROTEIN, APO-STRUCTURE, 2FE-2S, AROMATIC HYDROCARBONS CATABOLISM, DIOXYGENASE, IRON, IRON- SULFUR, METAL-BINDING, NAD, OXIDOREDUCTASE
1bim:A (PRO256) to (ALA285) CRYSTALLOGRAPHIC STUDIES ON THE BINDING MODES OF P2-P3 BUTANEDIAMIDE RENIN INHIBITORS | ASPARTIC PROTEINASE, ASPARTYL PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3fcs:C (PRO778) to (GLY822) STRUCTURE OF COMPLETE ECTODOMAIN OF INTEGRIN AIIBB3 | BETA PROPELLER, ROSSMANN FOLD, EGF DOMAIN, CELL ADHESION, DISEASE MUTATION, GLYCOPROTEIN, HOST-VIRUS INTERACTION, INTEGRIN, MEMBRANE, PHOSPHOPROTEIN, RECEPTOR, TRANSMEMBRANE, CELL ADHESION-IMMUNE SYSTEM COMPLEX, CELL ADHESION-BLOOD CLOTTING COMPLEX
4hwr:A (GLY463) to (LEU515) CRYSTAL STRUCTURE OF E. COLI THREONYL-TRNA SYNTHETASE BOUND TO A NOVEL INHIBITOR | AMINOACYL-TRNA SYNTHETASE, PROTEIN-INHIBITOR COMPLEX, ANTIBACTERIAL, LIGASE-LIGASE INHIBITOR COMPLEX
3fef:C (ARG202) to (LEU225) CRYSTAL STRUCTURE OF PUTATIVE GLUCOSIDASE LPLD FROM BACILLUS SUBTILIS | LPLD, GULOSIDASE, STRUCTURAL GENOMICS, UNKNOWN FUNCTION, GLYCOSIDASE, HYDROLASE, MANGANESE, METAL-BINDING, NAD, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
4hwt:A (GLY574) to (LEU627) CRYSTAL STRUCTURE OF HUMAN THREONYL-TRNA SYNTHETASE BOUND TO A NOVEL INHIBITOR | AMINOACYL-TRNA SYNTHETASE, PROTEIN-INHIBITOR COMPLEX, LIGASE-LIGASE INHIBITOR COMPLEX
4hwt:B (GLY574) to (LEU627) CRYSTAL STRUCTURE OF HUMAN THREONYL-TRNA SYNTHETASE BOUND TO A NOVEL INHIBITOR | AMINOACYL-TRNA SYNTHETASE, PROTEIN-INHIBITOR COMPLEX, LIGASE-LIGASE INHIBITOR COMPLEX
2pka:A (GLN30) to (GLY84) REFINED 2 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF PORCINE PANCREATIC KALLIKREIN A, A SPECIFIC TRYPSIN-LIKE SERINE PROTEINASE. CRYSTALLIZATION, STRUCTURE DETERMINATION, CRYSTALLOGRAPHIC REFINEMENT, STRUCTURE AND ITS COMPARISON WITH BOVINE TRYPSIN | SERINE PROTEINASE
2c0z:A (MET1) to (LEU27) THE 1.6 A RESOLUTION CRYSTAL STRUCTURE OF NOVW: A 4-KETO-6- DEOXY SUGAR EPIMERASE FROM THE NOVOBIOCIN BIOSYNTHETIC GENE CLUSTER OF STREPTOMYCES SPHEROIDES | ISOMERASE, EPIMERASE, ANTIBIOTIC BIOSYNTHESIS, RMLC-LIKE CUPIN
4xig:T (SER4) to (VAL36) CRYSTAL STRUCTURE OF BACTERIAL ALGINATE ABC TRANSPORTER DETERMINED THROUGH HUMID AIR AND GLUE-COATING METHOD | ABC, ALGINATE, SPHINGOMONAS, TRANSPORTER, TRANSPORT PROTEIN
4ia5:A (GLU253) to (ASP278) HYDRATASE FROM LACTOBACILLUS ACIDOPHILUS - SEMET DERIVATIVE (APO LAH) | CONJUGATED LINOLEIC ACID, CLA, MCRA, ROSSMANN FOLD, FAD BINDING, HYDRATASE, FATTY ACID, IMMUNE SYSTEM
4ia5:B (GLU253) to (ASP278) HYDRATASE FROM LACTOBACILLUS ACIDOPHILUS - SEMET DERIVATIVE (APO LAH) | CONJUGATED LINOLEIC ACID, CLA, MCRA, ROSSMANN FOLD, FAD BINDING, HYDRATASE, FATTY ACID, IMMUNE SYSTEM
4ibl:T (GLN110) to (SER161) RUBIDIUM SITES IN BLOOD COAGULATION FACTOR VIIA | SERINE PROTEASE, HYDROLASE, TISSUE FACTOR
4igl:A (SER901) to (VAL947) STRUCTURE OF THE RHS-REPEAT CONTAINING BC COMPONENT OF THE SECRETED ABC TOXIN COMPLEX FROM YERSINIA ENTOMOPHAGA | BETA-PROPELLER, RHS, TOXIN COMPLEX, TOXIN TRANSPORTER/CHAPERONE, SECRETED, TOXIN
4igl:C (SER901) to (VAL947) STRUCTURE OF THE RHS-REPEAT CONTAINING BC COMPONENT OF THE SECRETED ABC TOXIN COMPLEX FROM YERSINIA ENTOMOPHAGA | BETA-PROPELLER, RHS, TOXIN COMPLEX, TOXIN TRANSPORTER/CHAPERONE, SECRETED, TOXIN
2cmj:A (GLY150) to (GLN185) CRYSTAL STRUCTURE OF MOUSE CYTOSOLIC ISOCITRATE DEHYDROGENASE | OXIDOREDUCTASE, TRICARBOXYLIC ACID CYCLE, ISOCITRATE DEHYDROGENASE, NADP, GLYOXYLATE BYPASS
2cmv:A (GLY150) to (GLN185) CRYSTAL STRUCTURE OF MOUSE CYTOSOLIC ISOCITRATE DEHYDROGENASE COMPLEXED WITH CADMIUM AND CITRATE | TRICARBOXYLIC ACID CYCLE, ISOCITRATE DEHYDROGENASE, NADP, CADMIUM, OXIDOREDUCTASE, GLYOXYLATE BYPASS
2cmv:B (PRO149) to (GLN185) CRYSTAL STRUCTURE OF MOUSE CYTOSOLIC ISOCITRATE DEHYDROGENASE COMPLEXED WITH CADMIUM AND CITRATE | TRICARBOXYLIC ACID CYCLE, ISOCITRATE DEHYDROGENASE, NADP, CADMIUM, OXIDOREDUCTASE, GLYOXYLATE BYPASS
2qk7:B (SER219) to (LYS267) A COVALENT S-F HETERODIMER OF STAPHYLOCOCCAL GAMMA-HEMOLYSIN | PORE-FORMING TOXIN, BETA-BARREL, PROTEIN-PROTEIN INTERACTION, MOLECULAR PLASTICITY, COVALENT COMPLEX, CYTOLYSIS, HEMOLYSIS, SECRETED, TOXIN
4xtp:A (ASP64) to (VAL122) CRYSTAL STRUCTURE OF A RECOMBINANT VATAIREA MACROCARPA SEED LECTIN COMPLEXED WITH TN ANTIGEN | LEGUME, RECOMBINANT LECTIN, VATAIREA, TN ANTIGEN, SUGAR BINDING PROTEIN
1dp4:A (GLY370) to (ALA403) DIMERIZED HORMONE BINDING DOMAIN OF THE ATRIAL NATRIURETIC PEPTIDE RECEPTOR | PERIPLASMIC BINDING PROTEIN FOLD, DIMER, HORMONE/GROWTH FACTOR RECEPTOR, LYASE COMPLEX, HORMONE-GROWTH FACTOR RECEPTOR
1po3:B (TRP647) to (ASN707) CRYSTAL STRUCTURE OF FERRIC CITRATE TRANSPORTER FECA IN COMPLEX WITH FERRIC CITRATE | OUTER MEMBRANE PROTEIN, BETA BARREL, TONB-DEPENDENT TRANSPORT, CITRATE, SIDEROPHORE, IRON
1ps3:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH KIFUNENSINE | GLYCOSYL HYDROLASE, MANNOSIDASE, N-TERMINAL ALPHA-BETA DOMAIN, THREE HELIX BUNDLE, 2 C-TERMINAL BETA BARRELS, HYDROLASE
2qxx:A (GLY116) to (TRP141) BIFUNCTIONAL DCTP DEAMINASE: DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH DTTP | DISTORTED BETA BARREL, HYDROLASE, NUCLEOTIDE METABOLISM
2qxx:B (GLY116) to (TRP141) BIFUNCTIONAL DCTP DEAMINASE: DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH DTTP | DISTORTED BETA BARREL, HYDROLASE, NUCLEOTIDE METABOLISM
1e3h:A (PRO155) to (ALA203) SEMET DERIVATIVE OF STREPTOMYCES ANTIBIOTICUS PNPASE/GPSI ENZYME | POLYRIBONUCLEOTIDE TRANSFERASE, ATP:GTP DIPHOSPHOTRANSFERASE, RNA PROCESSING, RNA DEGRADATION
2d8b:A (TYR47) to (VAL100) SOLUTION STRUCTURE OF THE SECOND TANDEM COFILIN-DOMAIN OF MOUSE TWINFILIN | CELL-FREE PROTEIN SYNTHESIS, ACTIN-BINDING PROTEIN, DEVELOPMENTAL REGULATION, CELLULAR REMODELING, CYTOSKELETON, MORPHOLOGY, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, PROTEIN BINDING
3th4:T (GLN110) to (TYR157) MG2+ IS REQUIRED FOR OPTIMAL FOLDING OF THE GAMMA-CARBOXYGLUTAMIC ACID (GLA) DOMAINS OF VITAMIN K-DEPENDENT CLOTTING FACTORS AT PHYSIOLOGICAL CA2+ | HYDROLASE, SERINE PROTEASE, BLOOD CLOTTING, SOLUBLE TISSUE FACTOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1q38:A (ILE16) to (ARG68) ANASTELLIN | AMYLOID FIBRIL, ANASTELLIN, EXTRACELLULAR MATRIX, FIBRONECTIN TYPE 3 (FN3) DOMAIN, DYNAMIC FLUCTUATIONS, CONFORMATIONAL EXCHANGE, CHAPS, CELL ADHESION
1eag:A (VAL262) to (PHE298) SECRETED ASPARTIC PROTEINASE (SAP2) FROM CANDIDA ALBICANS COMPLEXED WITH A70450 | SAP2, CANDIDA ALBICANS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, ASPARTIC PROTEASE
3tiq:A (ILE555) to (ILE614) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS SASG G51-E-G52 MODULE | SINGLE-LAYER BETA SHEET, BIOFILM FORMATION, SURFACE, STRUCTURAL PROTEIN
3tiq:B (ILE555) to (ILE614) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS SASG G51-E-G52 MODULE | SINGLE-LAYER BETA SHEET, BIOFILM FORMATION, SURFACE, STRUCTURAL PROTEIN
3gw5:A (ILE268) to (ALA299) CRYSTAL STRUCTURE OF HUMAN RENIN COMPLEXED WITH A NOVEL INHIBITOR | RENIN, ASPARTATE PROTEASE, HYPERTENSION, RENIN EXPRESSION, RENIN INHIBITOR, ASPARTYL PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1qab:D (ALA29) to (GLY57) THE STRUCTURE OF HUMAN RETINOL BINDING PROTEIN WITH ITS CARRIER PROTEIN TRANSTHYRETIN REVEALS INTERACTION WITH THE CARBOXY TERMINUS OF RBP | HUMAN SERUM RETINOL BINDING PROTEIN, TRANSTHYRETIN, PREALBUMIN, TRANSPORT PROTEIN
3to6:A (PRO270) to (THR307) CRYSTAL STRUCTURE OF YEAST ESA1 HAT DOMAIN COMPLEXED WITH H4K16COA BISUBSTRATE INHIBITOR | ACETYLTRANSFERASE, AUTOACETYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3to7:A (PRO270) to (THR307) CRYSTAL STRUCTURE OF YEAST ESA1 HAT DOMAIN BOUND TO COENZYME A WITH ACTIVE SITE LYSINE ACETYLATED | MYST FAMILY, HISTONE ACETYLTRANSFERASE, TRANSFERASE
3h0o:A (GLY67) to (THR106) THE IMPORTANCE OF CH-PI STACKING INTERACTIONS BETWEEN CARBOHYDRATE AND AROMATIC RESIDUES IN TRUNCATED FIBROBACTER SUCCINOGENES 1,3-1,4-BETA-D-GLUCANASE | 1,3-1,4-BETA-D-GLUCANASE, CH-PI STACKING INTERACTIONS, TRIS INHIBITION, HYDROLASE, GLYCOSIDASE
1et6:A (LYS101) to (ALA130) CRYSTAL STRUCTURE OF THE SUPERANTIGEN SMEZ-2 FROM STREPTOCOCCUS PYOGENES | BETA GRASP, OB FOLD, SUPERANTIGEN FOLD, IMMUNE SYSTEM
1evk:B (GLY463) to (LEU515) CRYSTAL STRUCTURE OF A TRUNCATED FORM OF THREONYL-TRNA SYNTHETASE WITH THE LIGAND THREONINE | TRNA-SYNTHETASE, THREONINE, ZINC ION, DELETION MUTANT, LIGASE
3h4p:b (THR7) to (LYS38) PROTEASOME 20S CORE PARTICLE FROM METHANOCALDOCOCCUS JANNASCHII | 20S, PROTEASOME, CORE PARTICLE, HYDROLASE, PROTEASE, THREONINE PROTEASE
3h4p:d (THR7) to (LYS38) PROTEASOME 20S CORE PARTICLE FROM METHANOCALDOCOCCUS JANNASCHII | 20S, PROTEASOME, CORE PARTICLE, HYDROLASE, PROTEASE, THREONINE PROTEASE
3h4p:h (THR7) to (LYS38) PROTEASOME 20S CORE PARTICLE FROM METHANOCALDOCOCCUS JANNASCHII | 20S, PROTEASOME, CORE PARTICLE, HYDROLASE, PROTEASE, THREONINE PROTEASE
3h4p:j (THR7) to (LYS38) PROTEASOME 20S CORE PARTICLE FROM METHANOCALDOCOCCUS JANNASCHII | 20S, PROTEASOME, CORE PARTICLE, HYDROLASE, PROTEASE, THREONINE PROTEASE
3h4p:l (THR7) to (LYS38) PROTEASOME 20S CORE PARTICLE FROM METHANOCALDOCOCCUS JANNASCHII | 20S, PROTEASOME, CORE PARTICLE, HYDROLASE, PROTEASE, THREONINE PROTEASE
3h4z:C (VAL1112) to (LEU1154) CRYSTAL STRUCTURE OF AN MBP-DER P 7 FUSION PROTEIN | MBP FUSION, DERP7, AHA1/BPI DOMAIN-LIKE, SUPER ROLL, SUGAR TRANSPORT, TRANSPORT, ALLERGEN
1qwn:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II COVALENT INTERMEDIATE COMPLEX WITH 5- FLUORO-GULOSYL-FLUORIDE | N-TERMINAL ALPHA-BETA DOMAIN, THREE HELIX BUNDLE, 2 C-TERMINAL BETA BARRELS, FAMILY 38 GLYCOSYL HYDROLASE, HYDROLASE
1qwu:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II D341N MUTANT COMPLEX WITH 5-F-GULOSIDE | GLYCOSYL HYDROLASE FAMILY 38, COVALENT CATALYTIC INTERMEDIATE, HYDROLASE
1qx1:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II D341N MUTANT COMPLEX WITH 2-F-MANNOSYL-F | GLYCOSYL HYDROLASE FAMILY 38, COVALENT CATALYTIC INTERMEDIATE, HYDROLASE
2ec9:U (GLN110) to (TRP158) CRYSTAL STRUCTURE ANALYSIS OF HUMAN FACTOR VIIA , SOULUBLE TISSUE FACTOR COMPLEXED WITH BCX-3607 | PROTEIN-COFACTOR COMPLEX, FVIIA AND SOULUBLE TISSUE FACTOR, INHIBITOR, BLOOD CLOTTING
1r34:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH 5-THIO-D- MANNOPYRANOSYLAMIDINIUM SALT | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
2exh:D (TYR198) to (HIS264) STRUCTURE OF THE FAMILY43 BETA-XYLOSIDASE FROM GEOBACILLUS STEAROTHERMOPHILUS | GLYKOSIDASE, HYDROLSASE, XYLOSIDASE, FAMILY43, HYDROLASE
2exj:C (TYR198) to (LEU265) STRUCTURE OF THE FAMILY43 BETA-XYLOSIDASE D128G MUTANT FROM GEOBACILLUS STEAROTHERMOPHILUS IN COMPLEX WITH XYLOBIOSE | GLYKOSIDASE, HYDROLSASE, XYLOSIDASE, FAMILY43, XYLOSE, HYDROLASE
2exj:D (TYR198) to (HIS264) STRUCTURE OF THE FAMILY43 BETA-XYLOSIDASE D128G MUTANT FROM GEOBACILLUS STEAROTHERMOPHILUS IN COMPLEX WITH XYLOBIOSE | GLYKOSIDASE, HYDROLSASE, XYLOSIDASE, FAMILY43, XYLOSE, HYDROLASE
2exk:A (TYR198) to (HIS264) STRUCTURE OF THE FAMILY43 BETA-XYLOSIDASE E187G FROM GEOBACILLUS STEAROTHERMOPHILUS IN COMPLEX WITH XYLOBIOSE | GLYKOSIDASE, HYDROLSASE, XYLOSIDASE, FAMILY43, XYLOSE, HYDROLASE
2exk:D (TYR198) to (HIS264) STRUCTURE OF THE FAMILY43 BETA-XYLOSIDASE E187G FROM GEOBACILLUS STEAROTHERMOPHILUS IN COMPLEX WITH XYLOBIOSE | GLYKOSIDASE, HYDROLSASE, XYLOSIDASE, FAMILY43, XYLOSE, HYDROLASE
3ugt:B (LYS273) to (PHE323) CRYSTAL STRUCTURE OF THE YEAST MITOCHONDRIAL THREONYL-TRNA SYNTHETASE - ORTHORHOMBIC CRYSTAL FORM | THREONYL-TRNA SYNTHETASE, AMINOACYL-TRNA SYNTHETASE CLASS II, YEAST MITOCHONDRIAL THREONINE TRNA 1 AND 2, LIGASE
2f18:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH (2R,3R,4S)-2-({[(1R)-2- HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
2f1a:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH (2R,3R,4S)-2-({[(1S)-2- HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
2f1b:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH (2R,3R,4S,5R)-2-({[(1R)-2- HYDROXY-1-PHENYLETHYL]AMINO}METHYL)-5-METHYLPYRROLIDINE-3,4-DIOL | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
2v9x:C (HIS125) to (PRO151) E138D VARIANT OF ESCHERICHIA COLI DCTP DEAMINASE IN COMPLEX WITH DUTP | DUTPASE, HYDROLASE, DCTP DEAMINASE, NUCLEOTIDE METABOLISM
2v9x:H (HIS125) to (PRO151) E138D VARIANT OF ESCHERICHIA COLI DCTP DEAMINASE IN COMPLEX WITH DUTP | DUTPASE, HYDROLASE, DCTP DEAMINASE, NUCLEOTIDE METABOLISM
2v9x:I (HIS125) to (PRO151) E138D VARIANT OF ESCHERICHIA COLI DCTP DEAMINASE IN COMPLEX WITH DUTP | DUTPASE, HYDROLASE, DCTP DEAMINASE, NUCLEOTIDE METABOLISM
1fvi:A (SER199) to (GLY248) CRYSTAL STRUCTURE OF CHLORELLA VIRUS DNA LIGASE-ADENYLATE | ADENYLATED DNA LIGASE
3ul5:C (GLY63) to (LEU97) SACCHARUM OFFICINARUM CANECYSTATIN-1 IN SPACE GROUP C2221 | CYSTATIN, DEFENSE, HYDROLASE INHIBITOR
2f7p:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH BENZYL-MANNOSTATIN A | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
4yzs:A (VAL192) to (ARG267) CRYSTAL STRUCTURES REVEAL TRANSIENT PERK LUMINAL DOMAIN TETRAMERIZATION IN ER STRESS SIGNALING | PERK, UPR, ER STRESS, TETRAMER, UPR ACTIVATION, UPR SENSOR, UNFOLDED PROTEIN, PROTEOSTASIS, SIGNALING PROTEIN
4kgo:A (ILE137) to (VAL176) CRYSTAL STRUCTURE OF DOUBLE LEUCINE TO METHIONINE MUTANT HUMAN SPLUNC1 LACKING THE SECRETION SIGNAL SEQUENCE | BETA BARREL; BPI-LIKE FOLD, IMMUNE SYSTEM
2vec:A (TYR22) to (PHE54) THE CRYSTAL STRUCTURE OF THE PROTEIN YHAK FROM ESCHERICHIA COLI | ROS, BICUPIN, SULFENIC ACID, REACTIVE CYSTEINE, CYTOSOLIC PROTEIN
2vf7:A (GLY501) to (VAL531) CRYSTAL STRUCTURE OF UVRA2 FROM DEINOCOCCUS RADIODURANS | DNA-BINDING PROTEIN, NUCLEOTIDE-BINDING, ZINC-BINDING DOMAIN, SOS RESPONSE, METAL-BINDING, EXCISION NUCLEASE, ZINC-FINGER, ATP-BINDING, DNA-BINDING, DNA EXCISION, ZINC, CYTOPLASM, DNA DAMAGE, DNA REPAIR, ABC PROTEIN DNA-BINDING PROTEIN
2vf7:B (GLY501) to (VAL531) CRYSTAL STRUCTURE OF UVRA2 FROM DEINOCOCCUS RADIODURANS | DNA-BINDING PROTEIN, NUCLEOTIDE-BINDING, ZINC-BINDING DOMAIN, SOS RESPONSE, METAL-BINDING, EXCISION NUCLEASE, ZINC-FINGER, ATP-BINDING, DNA-BINDING, DNA EXCISION, ZINC, CYTOPLASM, DNA DAMAGE, DNA REPAIR, ABC PROTEIN DNA-BINDING PROTEIN
2vf7:C (GLY501) to (VAL531) CRYSTAL STRUCTURE OF UVRA2 FROM DEINOCOCCUS RADIODURANS | DNA-BINDING PROTEIN, NUCLEOTIDE-BINDING, ZINC-BINDING DOMAIN, SOS RESPONSE, METAL-BINDING, EXCISION NUCLEASE, ZINC-FINGER, ATP-BINDING, DNA-BINDING, DNA EXCISION, ZINC, CYTOPLASM, DNA DAMAGE, DNA REPAIR, ABC PROTEIN DNA-BINDING PROTEIN
2vf8:A (GLY501) to (VAL531) CRYSTAL STRUCTURE OF UVRA2 FROM DEINOCOCCUS RADIODURANS | NUCLEOTIDE-BINDING, ZINC-BINDING DOMAIN, SOS RESPONSE, METAL-BINDING, EXCISION NUCLEASE, ZINC-FINGER, ATP-BINDING, DNA-BINDING, DNA EXCISION, ZINC, CYTOPLASM, DNA DAMAGE, DNA REPAIR, ABC PROTEIN, DNA-BINDING PROTEIN
2vf8:B (GLY501) to (VAL531) CRYSTAL STRUCTURE OF UVRA2 FROM DEINOCOCCUS RADIODURANS | NUCLEOTIDE-BINDING, ZINC-BINDING DOMAIN, SOS RESPONSE, METAL-BINDING, EXCISION NUCLEASE, ZINC-FINGER, ATP-BINDING, DNA-BINDING, DNA EXCISION, ZINC, CYTOPLASM, DNA DAMAGE, DNA REPAIR, ABC PROTEIN, DNA-BINDING PROTEIN
1g9d:A (PRO378) to (ASP449) CRYSTAL STRUCTURE OF CLOSTRIDIUM BOTULINUM NEUROTOXIN B COMPLEXED WITH AN INHIBITOR (EXPERIMENT 2) | BOTULINUM, NEUROTOXIN, INHIBITOR, COMPLEX, HYDROLASE
4kmi:A (GLY267) to (ALA304) CRYSTAL STRUCTURE OF 4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE MGP COMPLEXED WITH PO4 | 5-BLADED BETA PROPELLER FOLD, PHOSPHORYLASE, MANNAN BIODEGRADATION, TRANSFERASE
1s21:A (GLY168) to (ASP204) CRYSTAL STRUCTURE OF AVRPPHF ORF2, A TYPE III EFFECTOR FROM P. SYRINGAE | PREDOMINANTLY BETA-STRAND, CHAPERONE
3hr9:A (GLY67) to (THR106) THE TRUNCATED FIBROBACTER SUCCINOGENES 1,3-1,4-BETA-D- GLUCANASE F40I MUTANT | 1,3-1,4-BETA-D-GLUCANASE, CARBOHYDRATE CH-PI STACKING INTERACTIONS, TRIS INHIBITION, HYDROLASE, GLYCOSIDASE
4zda:E (ARG196) to (LYS231) CRYSTAL STRUCTURE OF ISOCITRATE DEHYDROGENASE IN COMPLEX WITH ISOCITRATE AND MN FROM M. SMEGMATIS | ICD, M. SMEGMATIS, COMPLEX, ISOCITRATE, OXIDOREDUCTASE
4zda:F (ARG196) to (MET229) CRYSTAL STRUCTURE OF ISOCITRATE DEHYDROGENASE IN COMPLEX WITH ISOCITRATE AND MN FROM M. SMEGMATIS | ICD, M. SMEGMATIS, COMPLEX, ISOCITRATE, OXIDOREDUCTASE
2fyv:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH AN AMINO-SALACINOL CARBOXYLATE ANALOG | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
2g24:A (PRO259) to (ALA292) KETOPIPERAZINE-BASED RENIN INHIBITORS: OPTIMIZATION OF THE "C" RING | PROTEIN-LIGAND COMPLEXES, HYDROLASE
2g27:B (PRO259) to (ALA292) KETOPIPERAZINE-BASED RENIN INHIBITORS: OPTIMIZATION OF THE "C" RING | PROTEIN-LIGAND COMPLEXES, HYDROLASE
1gpw:B (LEU153) to (GLN176) STRUCTURAL EVIDENCE FOR AMMONIA TUNNELING ACROSS THE (BETA/ALPHA)8 BARREL OF THE IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE BIENZYME COMPLEX. | LYASE/TRANSFERASE, COMPLEX (LYASE/TRANSFERASE), HISTIDINE BIOSYNTHESIS, GLUTAMINASE, GLUTAMINE AMIDOTRANSFERASE, CYCLASE, AMMONIA CHANNEL
1gpw:F (GLY154) to (GLN176) STRUCTURAL EVIDENCE FOR AMMONIA TUNNELING ACROSS THE (BETA/ALPHA)8 BARREL OF THE IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE BIENZYME COMPLEX. | LYASE/TRANSFERASE, COMPLEX (LYASE/TRANSFERASE), HISTIDINE BIOSYNTHESIS, GLUTAMINASE, GLUTAMINE AMIDOTRANSFERASE, CYCLASE, AMMONIA CHANNEL
2vtc:A (ALA35) to (GLY85) THE STRUCTURE OF A GLYCOSIDE HYDROLASE FAMILY 61 MEMBER, CEL61B FROM THE HYPOCREA JECORINA. | HYDROLASE, GLYCOSIDE, CELLULASE
1syo:A (THR167) to (GLY208) N-TERMINAL 3 DOMAINS OF CI-MPR BOUND TO MANNOSE 6-PHOSPHATE | LECTIN; RECEPTOR; MANNOSE 6-PHOSPHATE, PROTEIN TRANSPORT,SUGAR BINDING PROTEIN
4l06:C (GLY150) to (GLN185) CRYSTAL STRUCTURE ANALYSIS OF HUMAN IDH1 MUTANTS IN COMPLEX WITH NADP+ AND CA2+/ALPHA-KETOGLUTARATE | CYTOSOLIC, OXIDOREDUCTASE
4l06:D (GLY150) to (GLN185) CRYSTAL STRUCTURE ANALYSIS OF HUMAN IDH1 MUTANTS IN COMPLEX WITH NADP+ AND CA2+/ALPHA-KETOGLUTARATE | CYTOSOLIC, OXIDOREDUCTASE
4l1k:A (GLU228) to (PRO271) CRYSTAL STRUCTURE OF D-ALANINE-D-ALNINE LIGASE FROM XANTHOMONAS ORYZAE PV. ORYZAE WITH AMPPNP | LIGASE
1t0l:A (GLY150) to (GLN185) CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NADP(+)-DEPENDENT ISOCITRATE DEHYDROGENASE IN COMPLEX WITH NADP, ISOCITRATE, AND CALCIUM(2+) | ROSSMANN FOLD, NADP, ISOCITRATE, CALCIUM, QUATERNARY COMPLEX, OXIDOREDUCTASE
1t0l:D (GLY150) to (GLN185) CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NADP(+)-DEPENDENT ISOCITRATE DEHYDROGENASE IN COMPLEX WITH NADP, ISOCITRATE, AND CALCIUM(2+) | ROSSMANN FOLD, NADP, ISOCITRATE, CALCIUM, QUATERNARY COMPLEX, OXIDOREDUCTASE
4l23:A (ARG401) to (GLY439) CRYSTAL STRUCTURE OF P110ALPHA COMPLEXED WITH NISH2 OF P85ALPHA AND PI-103 | ATP BINDING, PI-103, SIGNALING PROTEIN-TRANSFERASE-INHIBITOR COMPLEX
4l2y:A (ARG401) to (GLY439) CRYSTAL STRUCTURE OF P110ALPHA COMPLEXED WITH NISH2 OF P85ALPHA AND COMPOUND 9D | ATP BINDING, SIGNALING PROTEIN-TRANSFERASE-INHIBITOR COMPLEX
1t8s:A (ILE229) to (ASN277) CRYSTAL STRUCTURE OF E.COLI AMP NUCLEOSIDASE COMPLEXED WITH FORMICIN 5'-MONOPHOSPHATE | ALPHA-BETA-ALPHA SANDWICH, ALPHA-BETA FOLD, HYDROLASE
1t8s:B (ILE229) to (ASN277) CRYSTAL STRUCTURE OF E.COLI AMP NUCLEOSIDASE COMPLEXED WITH FORMICIN 5'-MONOPHOSPHATE | ALPHA-BETA-ALPHA SANDWICH, ALPHA-BETA FOLD, HYDROLASE
1t8s:C (ILE229) to (ASN277) CRYSTAL STRUCTURE OF E.COLI AMP NUCLEOSIDASE COMPLEXED WITH FORMICIN 5'-MONOPHOSPHATE | ALPHA-BETA-ALPHA SANDWICH, ALPHA-BETA FOLD, HYDROLASE
1t8s:D (ILE229) to (ASN277) CRYSTAL STRUCTURE OF E.COLI AMP NUCLEOSIDASE COMPLEXED WITH FORMICIN 5'-MONOPHOSPHATE | ALPHA-BETA-ALPHA SANDWICH, ALPHA-BETA FOLD, HYDROLASE
1t8s:E (ILE229) to (ASN277) CRYSTAL STRUCTURE OF E.COLI AMP NUCLEOSIDASE COMPLEXED WITH FORMICIN 5'-MONOPHOSPHATE | ALPHA-BETA-ALPHA SANDWICH, ALPHA-BETA FOLD, HYDROLASE
1t8s:F (ILE229) to (ASN277) CRYSTAL STRUCTURE OF E.COLI AMP NUCLEOSIDASE COMPLEXED WITH FORMICIN 5'-MONOPHOSPHATE | ALPHA-BETA-ALPHA SANDWICH, ALPHA-BETA FOLD, HYDROLASE
4lcv:D (ARG209) to (SER247) CRYSTAL STRUCTURE OF DOC2B C2A DOMAIN | C2, CALCIUM BINDING PROTEIN, METAL BINDING PROTEIN
3inm:C (GLY150) to (GLN185) CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NADP(+)-DEPENDENT ISOCITRATE DEHYDROGENASE R132H MUTANT IN COMPLEX WITH NADPH, ALPHA-KETOGLUTARATE AND CALCIUM(2+) | ROSSMANN FOLD, NADP, KETOGLUTARATE, QUATERNARY COMPLEX, OXIDOREDUCTASE, GLYOXYLATE BYPASS, MAGNESIUM, MANGANESE, METAL- BINDING, PEROXISOME, TRICARBOXYLIC ACID CYCLE
1hia:A (GLN30) to (GLY84) KALLIKREIN COMPLEXED WITH HIRUSTASIN | COMPLEX (PROTEASE/INHIBITOR), TISSUE KALLIKREIN, SERINE PROTEASE, TRYPSIN, PSA, KININ, SERPIN
1tqs:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH SALACINOL | HYDROLASE
1tqt:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH A DIASTEREOMER OF SALACINOL | N-TERMINAL ALPHA-BETA DOMAIN, THREE HELIX BUNDLE, 2 C-TERMINAL BETA BARRELS, FAMILY 38 GLYCOSYL HYDROLASE, HYDROLASE
1tqu:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH THE SALACINOL ANALOG GHAVAMIOL | HYDROLASE
1tqv:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH SELENO-SALACINOL (BLINTOL) | N-TERMINAL ALPHA-BETA DOMAIN, THREE HELIX BUNDLE, 2 C- TERMINAL BETA BARRELS, FAMILY 38 GLYCOSYL HYDROLASE
1tqw:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH A DIASTEREOMER OF SELENO- SALACINOL | HYDROLASE
1hty:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II | N-TERMINAL ALPHA-BETA DOMAIN, THREE HELIX BUNDLE, 2 C-TERMINAL BETA BARRELS, HYDROLASE
5a1t:A (HIS178) to (LYS207) TRICHOMONAS VAGINALIS LACTATE DEHYDROGENASE IN COMPLEX WITH NADH AND OXAMATE | OXIDOREDUCTASE, LACTATE DEHYDROGENASE
2wjr:A (LYS164) to (ARG208) NANC PORIN STRUCTURE IN RHOMBOHEDRAL CRYSTAL FORM. | CELL MEMBRANE, ION TRANSPORT, TRANSMEMBRANE, PORIN, MEMBRANE, TRANSPORT, BETA-BARREL, KDGM FAMILY, MEMBRANE PROTEIN, SIALIC ACID TRANSLOCATION, MONOMERIC PORIN, SUGAR TRANSPORT, CELL OUTER MEMBRANE, CARBOHYDRATE TRANSPORT, TRANSPORT PROTEIN
1hww:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH SWAINSONINE | N-TERMINAL ALPHA-BETA DOMAIN, THREE HELIX BUNDLE, 2 C-TERMINAL BETA BARRELS, HYDROLASE
2wjz:B (GLY154) to (GLN176) CRYSTAL STRUCTURE OF (HISH) K181A Y138A MUTANT OF IMIDAZOLEGLYCEROLPHOSPHATE SYNTHASE (HISH HISF) WHICH DISPLAYS CONSTITUTIVE GLUTAMINASE ACTIVITY | LYASE-TRANSFERASE COMPLEX, AMINO-ACID BIOSYNTHESIS, AMMONIA CHANNEL, HISTIDINE BIOSYNTHESIS, CYCLASE, GLUTAMINASE
2wjz:D (GLY154) to (GLN176) CRYSTAL STRUCTURE OF (HISH) K181A Y138A MUTANT OF IMIDAZOLEGLYCEROLPHOSPHATE SYNTHASE (HISH HISF) WHICH DISPLAYS CONSTITUTIVE GLUTAMINASE ACTIVITY | LYASE-TRANSFERASE COMPLEX, AMINO-ACID BIOSYNTHESIS, AMMONIA CHANNEL, HISTIDINE BIOSYNTHESIS, CYCLASE, GLUTAMINASE
2wjz:F (GLY154) to (GLN176) CRYSTAL STRUCTURE OF (HISH) K181A Y138A MUTANT OF IMIDAZOLEGLYCEROLPHOSPHATE SYNTHASE (HISH HISF) WHICH DISPLAYS CONSTITUTIVE GLUTAMINASE ACTIVITY | LYASE-TRANSFERASE COMPLEX, AMINO-ACID BIOSYNTHESIS, AMMONIA CHANNEL, HISTIDINE BIOSYNTHESIS, CYCLASE, GLUTAMINASE
1hxk:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH DEOXYMANNOJIRIMICIN | N-TERMINAL ALPHA-BETA DOMAIN, THREE HELIX BUNDLE, 2 C-TERMINAL BETA BARRELS, HYDROLASE
4lr4:A (THR264) to (THR297) CRYSTAL STRUCTURE OF A PUTATIVE SECRETED PROTEIN (EUBREC_3654) FROM EUBACTERIUM RECTALE AT 2.43 A RESOLUTION | AN ORPHAN, TWO DOMAINS PROTEIN, N-TERMINUS HAS A SANDWICH 10 STRANDS IN 2 SHEETS AND JELLY-ROLL FOLD, C -TERMINUS HAS GALACTOSE-BINDING DOMAIN-LIKE FOLD, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, UNKNOWN FUNCTION
4lr4:B (THR264) to (ASP303) CRYSTAL STRUCTURE OF A PUTATIVE SECRETED PROTEIN (EUBREC_3654) FROM EUBACTERIUM RECTALE AT 2.43 A RESOLUTION | AN ORPHAN, TWO DOMAINS PROTEIN, N-TERMINUS HAS A SANDWICH 10 STRANDS IN 2 SHEETS AND JELLY-ROLL FOLD, C -TERMINUS HAS GALACTOSE-BINDING DOMAIN-LIKE FOLD, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, UNKNOWN FUNCTION
4lr4:D (THR264) to (ASP303) CRYSTAL STRUCTURE OF A PUTATIVE SECRETED PROTEIN (EUBREC_3654) FROM EUBACTERIUM RECTALE AT 2.43 A RESOLUTION | AN ORPHAN, TWO DOMAINS PROTEIN, N-TERMINUS HAS A SANDWICH 10 STRANDS IN 2 SHEETS AND JELLY-ROLL FOLD, C -TERMINUS HAS GALACTOSE-BINDING DOMAIN-LIKE FOLD, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, UNKNOWN FUNCTION
4lt7:A (THR467) to (ASN503) CRYSTAL STRUCTURE OF THE C2A DOMAIN OF RABPHILIN-3A IN COMPLEX WITH A CALCIUM | CALCIUM BINDING, C2 DOMAIN, SIGNAL TRANSDUCTION, PROTEIN TRANSPORT
1i5p:A (ILE307) to (GLY349) INSECTICIDAL CRYSTAL PROTEIN CRY2AA | HELICAL BUNDLE, BETA PRISM, LECTIN-LIKE BETA SANDWICH, JELLY ROLL, TOXIN
2hzm:F (GLU212) to (THR247) STRUCTURE OF THE MEDIATOR HEAD SUBCOMPLEX MED18/20 | BETA BARREL, CHANNEL, TRANSCRIPTION
3wat:A (TRP268) to (ALA304) CRYSTAL STRUCTURE OF 4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE MGP COMPLEXED WITH MAN+GLC | 5-BLADED BETA PROPELLER FOLD, PHOSPHORYLASE, MANNAN BIODEGRADATION, TRANSFERASE
1j7x:A (HIS244) to (LEU273) CRYSTAL STRUCTURE OF A FUNCTIONAL UNIT OF INTERPHOTORECEPTOR RETINOID-BINDING PROTEIN (IRBP) | BETA BETA ALPHA SPIRAL, TRANSPORT PROTEIN
3wnk:A (PHE625) to (ASN659) CRYSTAL STRUCTURE OF BACILLUS CIRCULANS T-3040 CYCLOISOMALTOOLIGOSACCHARIDE GLUCANOTRANSFERASE | C2 TYPE IMMUNOGLOBULIN FOLD, (BETA/ALPHA)8-BARREL, BETA-JELLY ROLL, GREEK KEY, GLYCOSIDE HYDROLASE, ALPHA-1,6-GLUCAN, TRANSFERASE
2x9m:B (MET463) to (ASP515) HENDRA VIRUS ATTACHMENT GLYCOPROTEIN | PARAMYXOVIRUS, VIRAL SURFACE, NIPAH VIRUS, HENIPAVIRUS, VIRUS ENVELOPE, VIRAL ATTACHMENT, HNV, NIV-G, EFNB3, EFNB2, EPHRINB2, EPHRINB3, VIRAL PROTEIN
5amo:B (THR411) to (TYR437) STRUCTURE OF A MOUSE OLFACTOMEDIN-1 DISULFIDE-LINKED DIMER OF THE OLFACTOMEDIN DOMAIN AND PART OF THE COILED COIL | SIGNALING PROTEIN, OLFM1, DISULFIDE, NEUROBIOLOGY, DEVELOPMENT, AMPA RECEPTOR, BETA PROPELLER
1jdp:A (GLY365) to (MET399) CRYSTAL STRUCTURE OF HORMONE/RECEPTOR COMPLEX | HORMONE-RECEPTOR COMPLEX, NATRIURETIC PEPTIDE RECEPTOR, ALLOSTERIC ACTIVATION, SIGNALING PROTEIN
2ixl:D (LEU10) to (GLU38) RMLC S. SUIS WITH DTDP-RHAMNOSE | EPIMERISE, EPIMERASE, ISOMERASE, EPIMERIZE
3wvz:B (GLY49) to (LYS83) CRYSTAL STRUCTURE OF HIKESHI, A NEW NUCLEAR TRANSPORT RECEPTOR OF HSP70 | NUCLEAR TRANSPORT RECEPTOR, TRANSPORT PROTEIN
4mzq:C (PHE68) to (ALA108) BETA-ALANYL-COA:AMMONIA LYASE FROM CLOSTRIDIUM PROPIONICUM IN COMPLEX WITH PROPIONYL-COA | HOT DOG FOLD, LYASE
5b7m:C (SER271) to (THR297) STRUCTURE OF PERDEUTERATED CUEO - THE SIGNAL PEPTIDE WAS TRUNCATED BY HRV3C PROTEASE | MULTICOPPER OXIDASE, PERDEUTERATED, OXIDOREDUCTASE
5bw0:A (THR146) to (ASP201) THE CRYSTAL STRUCTURE OF MINOR PSEUDOPILIN BINARY COMPLEX OF XCPV AND XCPW FROM THE TYPE 2 SECRETION SYSTEM OF PSEUDOMONAS AERUGINOSA | PROTEIN TRANSPORT
5bw0:C (ALA147) to (ASP201) THE CRYSTAL STRUCTURE OF MINOR PSEUDOPILIN BINARY COMPLEX OF XCPV AND XCPW FROM THE TYPE 2 SECRETION SYSTEM OF PSEUDOMONAS AERUGINOSA | PROTEIN TRANSPORT
5bw0:G (THR146) to (ASP196) THE CRYSTAL STRUCTURE OF MINOR PSEUDOPILIN BINARY COMPLEX OF XCPV AND XCPW FROM THE TYPE 2 SECRETION SYSTEM OF PSEUDOMONAS AERUGINOSA | PROTEIN TRANSPORT
2jty:A (GLY35) to (THR76) SELF-COMPLEMENTED VARIANT OF FIMA, THE MAIN SUBUNIT OF TYPE 1 PILUS | PROTEIN/PILI/FIM, CELL PROJECTION, FIMBRIUM, CHIMERA, CHAPERONE, STRUCTURAL PROTEIN
2jz4:A (ALA228) to (ALA257) PUTATIVE 32 KDA MYROSINASE BINDING PROTEIN AT3G16450.1 FROM ARABIDOPSIS THALIANA | MYROSINASE BINDING PROTEIN, AT3G16450.1, SAIL, STEREO-ARRAY ISOTOPE LABELING, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS, CESG, UNKNOWN FUNCTION
4nkq:A (PRO291) to (GLN324) STRUCTURE OF A CYTOKINE RECEPTOR COMPLEX | GM-CSF, RECEPTOR COMPLEX, DODECAMER, DISEASE MUTATION, GLYCOPROTEIN, MEMBRANE, PHOSPHOPROTEIN, TRANSMEMBRANE, CYTOKINE, GROWTH FACTOR, SECRETED, CYTOKINE-CYTOKINE RECEPTOR COMPLEX
2knt:A (LYS9) to (ARG32) THE 1.2 ANGSTROM STRUCTURE OF KUNITZ TYPE DOMAIN C5 | KUNITZ INHIBITOR, EXTRACELLULAR MATRIX, CONNECTIVE TISSUE
3zr4:B (GLY154) to (GLN176) STRUCTURAL EVIDENCE FOR AMMONIA TUNNELING ACROSS THE (BETA- ALPHA)8 BARREL OF THE IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE BIENZYME COMPLEX | TRANSFERASE
3zr4:D (GLY154) to (GLN176) STRUCTURAL EVIDENCE FOR AMMONIA TUNNELING ACROSS THE (BETA- ALPHA)8 BARREL OF THE IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE BIENZYME COMPLEX | TRANSFERASE
4np9:A (ARG465) to (ASN503) STRUCTURE OF RABPHILIN C2A DOMAIN BOUND TO IP3 | RABPHILIN-3A, C2 DOMAIN, C2A, CALCIUM BINDING, SYNAPTIC EXOCYTOSIS METAL-BINDING, PROTEIN TRANSPORT, C-2 DOMAIN FOLD, EXOPHILIN-1
4ns0:A (THR467) to (ASN503) THE C2A DOMAIN OF RABPHILIN 3A IN COMPLEX WITH PI(4,5)P2 | C2 DOMAIN, CALCIUM BINDING, PHOSPHOLIPID BINDING, RABPHILIN-3A, C2A, SYNAPTIC EXOCYTOSIS METAL-BINDING, PROTEIN TRANSPORT, C-2 DOMAIN FOLD, EXOPHILIN-1
2yet:B (ILE91) to (ALA130) THERMOASCUS GH61 ISOZYME A | HYDROLASE, DEGRADATION OF BIOMASS
1kpq:A (ILE59) to (VAL89) STRUCTURE OF THE TSG101 UEV DOMAIN | E2 FOLD, CELL CYCLE
1kxj:A (GLY154) to (GLN176) THE CRYSTAL STRUCTURE OF GLUTAMINE AMIDOTRANSFERASE FROM THERMOTOGA MARITIMA | ALPHA-BETA-ALPHA, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, TRANSFERASE
2nmt:A (VAL310) to (GLY348) MYRISTOYL-COA:PROTEIN N-MYRISTOYLTRANSFERASE BOUND TO MYRISTOYL-COA AND PEPTIDE ANALOGS | TRANSFERASE ACYLTRANSFERASE, TRANSFERASE
3jd2:A (ASN56) to (SER96) GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, OPEN CONFORMATION | GLUTAMATE METABOLISM, MITOCHONDRIA, OXIDOREDUCTASE
3jd2:B (ASN56) to (SER96) GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, OPEN CONFORMATION | GLUTAMATE METABOLISM, MITOCHONDRIA, OXIDOREDUCTASE
3jd2:C (ASN56) to (SER96) GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, OPEN CONFORMATION | GLUTAMATE METABOLISM, MITOCHONDRIA, OXIDOREDUCTASE
3jd2:D (ASN56) to (SER96) GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, OPEN CONFORMATION | GLUTAMATE METABOLISM, MITOCHONDRIA, OXIDOREDUCTASE
3jd2:E (ASN56) to (SER96) GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, OPEN CONFORMATION | GLUTAMATE METABOLISM, MITOCHONDRIA, OXIDOREDUCTASE
3jd2:F (ASN56) to (SER96) GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, OPEN CONFORMATION | GLUTAMATE METABOLISM, MITOCHONDRIA, OXIDOREDUCTASE
1xfd:C (ASN206) to (SER231) STRUCTURE OF A HUMAN A-TYPE POTASSIUM CHANNEL ACCELERATING FACTOR DPPX, A MEMBER OF THE DIPEPTIDYL AMINOPEPTIDASE FAMILY | DPPX; DPP6; KV4; KV; KAF, MEMBRANE PROTEIN
1xgm:A (SER151) to (GLU199) METHIONINE AMINOPEPTIDASE FROM HYPERTHERMOPHILE PYROCOCCUS FURIOSUS | AMINOPEPTIDASE, HYPERTHERMOPHILE
5cfn:A (GLU266) to (ALA302) CRYSTAL STRUCTURE OF ANEMONE STING (NEMATOSTELLA VECTENSIS) IN COMPLEX WITH 3',3' C-DI-AMP, C[A(3',5')PA(3',5')P] | STING, CYCLIC-DINUCLEOTIDE BINDING DOMAIN, IMMUNE SYSTEM
1xkw:A (ARG637) to (ASN687) PYOCHELIN OUTER MEMBRANE RECEPTOR FPTA FROM PSEUDOMONAS AERUGINOSA | TONB DEPENDENT RECEPTOR, MEMBRANE PROTEIN
3k80:D (GLY29) to (HIS69) STRUCTURE OF ESSENTIAL PROTEIN FROM TRYPANOSOMA BRUCEI | RNA-EDITING, OB-FOLD, RNA-BINDING PROTEINS, IMMUNE SYSTEM, RNA BINDING PROTEIN
1xs1:A (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI IN COMPLEX WITH DUTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs1:C (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI IN COMPLEX WITH DUTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs1:D (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI IN COMPLEX WITH DUTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs1:E (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI IN COMPLEX WITH DUTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs1:F (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI IN COMPLEX WITH DUTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs4:A (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI- E138A MUTANT ENZYME IN COMPLEX WITH DCTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs4:B (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI- E138A MUTANT ENZYME IN COMPLEX WITH DCTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs4:D (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI- E138A MUTANT ENZYME IN COMPLEX WITH DCTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs4:E (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI- E138A MUTANT ENZYME IN COMPLEX WITH DCTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs4:F (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI- E138A MUTANT ENZYME IN COMPLEX WITH DCTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs6:A (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI. E138A MUTANT ENZYME IN COMPLEX WITH DUTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs6:B (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI. E138A MUTANT ENZYME IN COMPLEX WITH DUTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs6:C (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI. E138A MUTANT ENZYME IN COMPLEX WITH DUTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs6:D (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI. E138A MUTANT ENZYME IN COMPLEX WITH DUTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs6:E (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI. E138A MUTANT ENZYME IN COMPLEX WITH DUTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1xs6:F (HIS125) to (PRO151) DCTP DEAMINASE FROM ESCHERICHIA COLI. E138A MUTANT ENZYME IN COMPLEX WITH DUTP | DCTP DEAMINASE, NUCLEOTIDE METABOLISM, TRIMER, HYDROLASE
1mj9:A (LEU272) to (THR307) CRYSTAL STRUCTURE OF YEAST ESA1(C304S) MUTANT COMPLEXED WITH COENZYME A | ESA1, HAT, HISTONE ACETYLTRANSFERASE, MYST, TRANSFERASE
4p1x:A (TYR246) to (LEU290) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL LUK PREPORE | PORE FORMING TOXIN, TOXIN
4p1x:C (SER220) to (LYS268) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL LUK PREPORE | PORE FORMING TOXIN, TOXIN
4p1x:E (SER220) to (LYS268) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL LUK PREPORE | PORE FORMING TOXIN, TOXIN
3km4:A (ILE268) to (ALA299) OPTIMIZATION OF ORALLY BIOAVAILABLE ALKYL AMINE RENIN INHIBITORS | RENIN, ASPARTATE PROTEASE, HYPERTENSION, RENIN EXPRESSION, RENIN INHIBITOR, ASPARTYL PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, PROTEASE, SECRETED, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3km4:B (ILE268) to (ALA299) OPTIMIZATION OF ORALLY BIOAVAILABLE ALKYL AMINE RENIN INHIBITORS | RENIN, ASPARTATE PROTEASE, HYPERTENSION, RENIN EXPRESSION, RENIN INHIBITOR, ASPARTYL PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, PROTEASE, SECRETED, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4p1y:E (TYR246) to (LEU290) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL GAMMA-HEMOLYSIN PREPORE | PORE FORMING TOXIN
4p3n:A (GLY541) to (LEU594) STRUCTURAL BASIS FOR FULL-SPECTRUM INHIBITION OF THREONYL-TRNA SYNTHETASE BY BORRELIDIN 1 | SYNTHETASE, INHIBITOR, LIGASE-LIGASE INHIBITOR COMPLEX
4p3n:D (LYS543) to (LEU594) STRUCTURAL BASIS FOR FULL-SPECTRUM INHIBITION OF THREONYL-TRNA SYNTHETASE BY BORRELIDIN 1 | SYNTHETASE, INHIBITOR, LIGASE-LIGASE INHIBITOR COMPLEX
3kpt:B (ASN163) to (GLU200) CRYSTAL STRUCTURE OF BCPA, THE MAJOR PILIN SUBUNIT OF BACILLUS CEREUS | INTRAMOLECULAR AMIDE BOND, PILIN SUBUNIT, BETA SHEET
3a3k:A (GLY370) to (ALA403) REVERSIBLY BOUND CHLORIDE IN THE ATRIAL NATRIURETIC PEPTIDE RECEPTOR HORMONE-BINDING DOMAIN | NATRIURETIC PEPTIDE RECEPTOR, GUANYLYL-CYCLASE-COUPLED RECEPTOR, CHLORIDE BINDING MOTIF, SIGNAL TRANSDUCTION, SIGNALING PROTEIN, MEMBRANE PROTEIN, CGMP BIOSYNTHESIS, CHLORIDE, DISULFIDE BOND, GLYCOPROTEIN, GTP-BINDING, LYASE, MEMBRANE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, RECEPTOR, TRANSMEMBRANE
3a3k:B (GLY370) to (ALA403) REVERSIBLY BOUND CHLORIDE IN THE ATRIAL NATRIURETIC PEPTIDE RECEPTOR HORMONE-BINDING DOMAIN | NATRIURETIC PEPTIDE RECEPTOR, GUANYLYL-CYCLASE-COUPLED RECEPTOR, CHLORIDE BINDING MOTIF, SIGNAL TRANSDUCTION, SIGNALING PROTEIN, MEMBRANE PROTEIN, CGMP BIOSYNTHESIS, CHLORIDE, DISULFIDE BOND, GLYCOPROTEIN, GTP-BINDING, LYASE, MEMBRANE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, RECEPTOR, TRANSMEMBRANE
1yk1:A (GLY365) to (MET399) STRUCTURE OF NATRIURETIC PEPTIDE RECEPTOR-C COMPLEXED WITH BRAIN NATRIURETIC PEPTIDE | HORMONE-RECEPTOR COMPLEX, NATRIURETIC PEPTIDE RECEPTOR, ALLOSTERIC ACTIVATION, HORMONE-GROWTH FACTOR RECEPTOR COMPLEX
1yk1:B (GLY365) to (MET399) STRUCTURE OF NATRIURETIC PEPTIDE RECEPTOR-C COMPLEXED WITH BRAIN NATRIURETIC PEPTIDE | HORMONE-RECEPTOR COMPLEX, NATRIURETIC PEPTIDE RECEPTOR, ALLOSTERIC ACTIVATION, HORMONE-GROWTH FACTOR RECEPTOR COMPLEX
4pkm:A (VAL244) to (SER293) CRYSTAL STRUCTURE OF BACILLUS THURINGIENSIS CRY51AA1 PROTOXIN AT 1.65 ANGSTROMS RESOLUTION | BACTERIAL TOXINS, CRY TOXINS, PORE-FORMING TOXINS, BETA-PORE-FORMING TOXINS, BEETLES, INSECTICIDAL TOXINS, PRO-TOXINS, TOXIN
3agy:B (CYS179) to (PHE220) CRYSTAL STRUCTURE OF HUMAN HSP40 HDJ1 PEPTIDE-BINDING DOMAIN COMPLEXED WITH A C-TERMINAL PEPTIDE OF HSP70 | CHAPERONE
5dmb:A (ASP88) to (GLN123) CRYSTAL STRUCTURE OF A TRANSLATIONAL REGULATOR BOUND TO A FLAGELLAR ASSEMBLY FACTOR | TRANSLATION, FLAGELLUM, ASSEMBLY FACTOR
4akm:A (GLY288) to (ALA325) CRYSTAL STRUCTURE OF THE HUMAN LYSOSOME-ASSOCIATED MEMBRANE PROTEIN LAMP-3 (AKA DC-LAMP) | MEMBRANE PROTEIN, GLYCOSYLATION, BETA PRISM
4akm:B (PHE289) to (ALA325) CRYSTAL STRUCTURE OF THE HUMAN LYSOSOME-ASSOCIATED MEMBRANE PROTEIN LAMP-3 (AKA DC-LAMP) | MEMBRANE PROTEIN, GLYCOSYLATION, BETA PRISM
4pph:C (VAL331) to (LEU360) CRYSTAL STRUCTURE OF CONGLUTIN GAMMA, A UNIQUE BASIC 7S GLOBULIN FROM LUPINE SEEDS | PLANT PROTEIN, LUPINE COTYLEDONS, NON-STORAGE ROLE, 7S BASIC GLOBULIN, GLYCOSIDE-HYDROLASE-INHIBITOR-LIKE PROTEIN, APIGENIN GLYCOSIDES, N-LINKED GLYCOSYLATION, INSULIN
4pv1:D (ASP87) to (ASP134) CYTOCHROME B6F STRUCTURE FROM M. LAMINOSUS WITH THE QUINONE ANALOG INHIBITOR STIGMATELLIN | ALPHA HELIX, BETA SHEET, PLASTOQUINOL:PLASTOCYANIN OXIDOREDUCTASE, PLASTOCYANIN, THYLAKOID MEMBRANE, ELECTRON TRANSPORT-INHIBITOR COMPLEX
4pyv:A (ASP257) to (ALA285) CRYSTAL STRUCTURE OF RENIN IN COMPLEX WITH COMPOUND4 | RENIN INHIBITOR, 3,5-SUBSTITUTED PIPERIDINES, HYDROLASE INHIBITOR COMPLEX, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3aog:J (LYS44) to (HIS84) CRYSTAL STRUCTURE OF GLUTAMATE DEHYDROGENASE (GDHB) FROM THERMUS THERMOPHILUS (GLU BOUND FORM) | GLUTAMATE DEHYDROGENASE, DEHYDROGENASE, NAD(H), OXIDOREDUCTASE
3axd:B (GLY67) to (THR100) THE TRUNCATED FIBROBACTER SUCCINOGENES 1,3-1,4-BETA-D-GLUCANASE V18Y/W203Y IN APO-FORM | GLUCANASE, CELLOBIOSE/CELLOTETRAOSE, HYDROLASE
3axe:A (GLY67) to (THR106) THE TRUNCATED FIBROBACTER SUCCINOGENES 1,3-1,4-BETA-D-GLUCANASE V18Y/W203Y IN COMPLEX WITH CELLOTETRAOSE (CELLOBIOSE DENSITY WAS OBSERVED) | GLUCANASE, CELLOBIOSE/CELLOTETRAOSE, HYDROLASE
3m3y:B (ILE90) to (GLY168) RNA POLYMERASE II ELONGATION COMPLEX C | TRANSCRIPTION, MRNA, MULTIPROTEIN COMPLEX, MOLECULAR MACHINE, DNA, DNA DAMAGE, CANCER, PLATINUM DRUG, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, METAL-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
4b4p:A (SER44) to (GLN84) CRYSTAL STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF. | CELL ADHESION, FIMBRIAE, BACTERIAL ADHESINS, PROTEIN-CARBOHYDRATE INTERACTIONS, ABH BLOOD GROUP BINDING, STEC, ETEC, SPR, MST, BSI
4b4q:A (SER58) to (SER97) CRYSTAL STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF IN COMPLEX WITH BLOOD GROUP A TYPE 1 HEXASACCHARIDE | CELL ADHESION, BACTERIAL ADHESINS, PROTEIN-CARBOHYDRATE INTERACTIONS, ABH BLOOD GROUP BINDING, STEC, ETEC, SPR, MST, BSI
4b4r:A (SER58) to (SER97) CRYSTAL STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF IN COMPLEX WITH BLOOD GROUP B TYPE 1 HEXASACCHARIDE | CELL ADHESION, FIMBRIAE, BACTERIAL ADHESINS, PROTEIN-CARBOHYDRATE INTERACTIONS, ABH BLOOD GROUP BINDING
4b60:A (GLU204) to (SER248) STRUCTURE OF RFNBPA(189-505) IN COMPLEX WITH FIBRINOGEN GAMMA CHAIN C-TERMINAL PEPTIDE | CELL ADHESION, FNBPA, FIBRINOGEN, FIBRINOGEN BINDING
3azy:A (TRP28) to (ARG68) CRYSTAL STRUCTURE OF THE LAMINARINASE CATALYTIC DOMAIN FROM THERMOTOGA MARITIMA MSB8 | BETA-JELLY ROLL FOLD, GLYCOSYL HYDROLASE FAMILY 16, LAMINARINASE, ENDO-1,3-BETA-GLUCANASE, HYDROLASE
3azy:D (TRP28) to (ARG68) CRYSTAL STRUCTURE OF THE LAMINARINASE CATALYTIC DOMAIN FROM THERMOTOGA MARITIMA MSB8 | BETA-JELLY ROLL FOLD, GLYCOSYL HYDROLASE FAMILY 16, LAMINARINASE, ENDO-1,3-BETA-GLUCANASE, HYDROLASE
3azz:A (ILE27) to (ARG68) CRYSTAL STRUCTURE OF THE LAMINARINASE CATALYTIC DOMAIN FROM THERMOTOGA MARITIMA MSB8 IN COMPLEX WITH GLUCONOLACTONE | BETA-JELLY ROLL FOLD, GLYCOSYL HYDROLASE FAMILY 16, LAMINARINASE, ENDO-1,3-BETA-GLUCANASE, HYDROLASE
3b00:A (TRP28) to (ARG68) CRYSTAL STRUCTURE OF THE LAMINARINASE CATALYTIC DOMAIN FROM THERMOTOGA MARITIMA MSB8 IN COMPLEX WITH CETYLTRIMETHYLAMMONIUM BROMIDE | BETA-JELLY ROLL FOLD, GLYCOSYL HYDROLASE FAMILY 16, LAMINARINASE, ENDO-1,3-BETA-GLUCANASE, HYDROLASE
3b00:D (TRP28) to (ARG68) CRYSTAL STRUCTURE OF THE LAMINARINASE CATALYTIC DOMAIN FROM THERMOTOGA MARITIMA MSB8 IN COMPLEX WITH CETYLTRIMETHYLAMMONIUM BROMIDE | BETA-JELLY ROLL FOLD, GLYCOSYL HYDROLASE FAMILY 16, LAMINARINASE, ENDO-1,3-BETA-GLUCANASE, HYDROLASE
3b01:A (TRP28) to (ARG68) CRYSTAL STRUCTURE OF THE LAMINARINASE CATALYTIC DOMAIN FROM THERMOTOGA MARITIMA MSB8 | BETA-JELLY ROLL FOLD, GLYCOSYL HYDROLASE FAMILY 16, LAMINARINASE, ENDO-1,3-BETA-GLUCANASE, HYDROLASE
3b01:D (TRP28) to (ARG68) CRYSTAL STRUCTURE OF THE LAMINARINASE CATALYTIC DOMAIN FROM THERMOTOGA MARITIMA MSB8 | BETA-JELLY ROLL FOLD, GLYCOSYL HYDROLASE FAMILY 16, LAMINARINASE, ENDO-1,3-BETA-GLUCANASE, HYDROLASE
3mas:A (GLY150) to (GLN185) CRYSTAL STRUCTURE OF HETERODIMERIC R132H MUTANT OF HUMAN CYTOSOLIC NADP(+)-DEPENDENT ISOCITRATE DEHYDROGENASE IN COMPLEX WITH NADP AND ISOCITRATE | ISOCITRATE DEHYDROGENASE, NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE, ROSSMANN FOLD, OXIDOREDUCTASE
3mbc:A (GLU193) to (ALA227) CRYSTAL STRUCTURE OF MONOMERIC ISOCITRATE DEHYDROGENASE FROM CORYNEBACTERIUM GLUTAMICUM IN COMPLEX WITH NADP | HOLOENZYME, APOENZYME, OPEN CONFORMATION, NADP, GLYOXYLATE BYPASS, MAGNESIUM, METAL-BINDING, OXIDOREDUCTASE, TRICARBOXYLIC ACID CYCLE
3mbc:B (ASP192) to (ALA227) CRYSTAL STRUCTURE OF MONOMERIC ISOCITRATE DEHYDROGENASE FROM CORYNEBACTERIUM GLUTAMICUM IN COMPLEX WITH NADP | HOLOENZYME, APOENZYME, OPEN CONFORMATION, NADP, GLYOXYLATE BYPASS, MAGNESIUM, METAL-BINDING, OXIDOREDUCTASE, TRICARBOXYLIC ACID CYCLE
2aer:T (GLN110) to (TYR157) CRYSTAL STRUCTURE OF BENZAMIDINE-FACTOR VIIA/SOLUBLE TISSUE FACTOR COMPLEX. | SERINE PROTEASE, CALCIUM, MAGNESIUM, ZINC, SODIUM, FACTOR VIIA, TISSUE FACTOR, BENZAMIDINE, BLOOD COAGULATION, CLOTTING, BLOOD, COAGULATION, CLOTTING FACTOR, COAGULATION FACTOR, BLOOD CLOTTING
3mq4:A (PRO474) to (ILE506) METABOTROPIC GLUTAMATE RECEPTOR MGLUR7 COMPLEXED WITH LY341495 ANTAGONIST | GLUTAMATE RECEPTORS, MGLUR7, DIMERIZATION, GLUTAMIC ACID BINDING, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, SIGNALING PROTEIN
3bub:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II WITH AN EMPTY ACTIVE SITE | GLYCOSYL HYDROLASE FAMILY 38, GLYCOSIDASE, GOLGI APPARATUS, MEMBRANE, SIGNAL-ANCHOR, TRANSMEMBRANE, HYDROLASE
3bui:A (PHE804) to (GLY849) GOLGI MANNOSIDASE II D204A CATALYTIC NUCLEOPHILE MUTANT COMPLEX WITH TRIS | GLYCOSYL HYDROLASE FAMILY 38, GLYCOSIDASE, GOLGI APPARATUS, MEMBRANE, SIGNAL-ANCHOR, TRANSMEMBRANE
3bup:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II D341N ACID-BASE CATALYST MUTANT WITH BOUND MANNOSE | GLYCOSYL HYDROLASE FAMILY 38, GLYCOSIDASE, GOLGI APPARATUS, MEMBRANE, SIGNAL-ANCHOR, TRANSMEMBRANE, HYDROLASE
3buq:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II D204A CATALYTIC NUCLEOPHILE MUTANT WITH BOUND MANNOSE. | GLYCOSYL HYDROLASE FAMILY 38, GLYCOSIDASE, GOLGI APPARATUS, MEMBRANE, SIGNAL-ANCHOR, TRANSMEMBRANE, HYDROLASE
3bvu:A (PHE804) to (GLY849) GOLGI MANNOSIDASE II D204A CATALYTIC NUCLEOPHILE MUTANT COMPLEX WITH METHYL(ALPHA-D-MANNOPYRANOSYL)-(1->3)-S-[(ALPHA-D-MANNOPYRANOSYL)-(1- >6)]-ALPHA-D-MANNOPYRANOSIDE | FAMILY 38 GLYCOYSL HYDROLASE, GLYCOSIDASE, GOLGI APPARATUS, MEMBRANE, SIGNAL-ANCHOR, TRANSMEMBRANE, HYDROLASE
3bvv:A (PHE804) to (GLN850) GOLGI MANNOSIDASE II D204A CATALYTIC NUCLEOPHILE MUTANT COMPLEX WITH METHYL ALPHA-D-MANNOPYRANOSYL-(1->3)-[6-THIO- ALPHA-D-MANNOPYRANOSYL-(1->6)]-BETA-D-MANNOPYRANOSIDE | FAMILY 38 GLYCOYSL HYDROLASE, GLYCOSIDASE, GOLGI APPARATUS, MEMBRANE, SIGNAL-ANCHOR, TRANSMEMBRANE
3bvx:A (PHE804) to (GLY849) GOLGI MANNOSIDASE II D204A CATALYTIC NUCLEOPHILE MUTANT COMPLEX WITH METHYL (2-DEOXY-2-ACETAMIDO-BETA-D- GLUCOPYRANOSYL)-(1->2)-(ALPHA-D-MANNOPYRANOSYL)- (1->3)- [(ALPHA-D-MANNOPYRANOSYL)-(1->6)-(ALPHA-D-MANNOPYRANOSYL)- (1->6)]-BETA-D-MANNOPYRANOSIDE | FAMILY 38 GLYCOYSL HYDROLASE, GLYCOSIDASE, GOLGI APPARATUS, MEMBRANE, SIGNAL-ANCHOR, TRANSMEMBRANE
3bxb:B (PHE88) to (VAL119) MONOMERIC FAR-RED FLUORESCENT PROTEIN MKATE CRYSTALLIZED AT PH 7.0 | FAR-RED FLUORESCENT PROTEIN, E. QUADRICOLOR, CHROMOPHORE STRUCTURE, PH-INDUCED CIS-TRANS IZOMERIZATION
3bxb:E (PHE88) to (VAL119) MONOMERIC FAR-RED FLUORESCENT PROTEIN MKATE CRYSTALLIZED AT PH 7.0 | FAR-RED FLUORESCENT PROTEIN, E. QUADRICOLOR, CHROMOPHORE STRUCTURE, PH-INDUCED CIS-TRANS IZOMERIZATION
4r7v:A (LYS7) to (LYS45) CRYSTAL STRUCTURE OF N-LOBE OF HUMAN ARRDC3(1-165) | ARRESTIN FOLD, GPCR DOWN REGULATION, BETA 2 ADRENERGIC RECEPTOR, PROTEIN BINDING
4rap:L (TRP41) to (LEU92) CRYSTAL STRUCTURE OF BACTERIAL IRON-CONTAINING DODECAMERIC GLYCOSYLTRANSFERASE TIBC FROM ENTEROTOXIGENIC E.COLI H10407 | GT-B FOLD, TRANSFERASE, TIBA, ADP-HEPTOSE
3ci0:J (ASP144) to (ARG189) THE CRYSTAL STRUCTURE OF THE GSPK-GSPI-GSPJ COMPLEX FROM ENTEROTOXIGENIC ESCHERICHIA COLI TYPE 2 SECRETION SYSTEM | GENERAL SECRETORY PATHWAY, PSEUDOPILUS, TYPE 4 PILIN BIOGENESIS, METHYLATION, PROTEIN TRANSPORT
4cak:A (GLN611) to (GLU646) THREE-DIMENSIONAL RECONSTRUCTION OF INTACT HUMAN INTEGRIN ALPHAIIBBETA3 IN A PHOSPHOLIPID BILAYER NANODISC | CELL ADHESION, INTEGRIN, SINGLE PARTICLE RECONSTRUCTION
4rus:B (GLY18) to (ASN58) CARP FISHELECTIN, HOLO FORM | SIX-BLADE BETA PROPELLER, LECTIN, EGGS, SUGAR BINDING PROTEIN
3cv5:A (PHE804) to (GLN850) GOLGI MANNOSIDASE II D204A CATALYTIC NUCLEOPHILE MUTANT COMPLEX WITH 3ALPHA,6ALPHA-MANNOPENTAOSE | FAMILY 38 GLYCOSYL HYDROLASE, GLYCOSIDASE, GOLGI APPARATUS, MEMBRANE, METAL-BINDING, SIGNAL-ANCHOR, TRANSMEMBRANE, HYDROLASE
3cxp:A (ASP83) to (VAL119) CRYSTAL STRUCTURE OF HUMAN GLUCOSAMINE 6-PHOSPHATE N- ACETYLTRANSFERASE 1 MUTANT E156A | GNA1, ACYLTRANSFERASE, ENDOSOME, GOLGI APPARATUS, MEMBRANE, TRANSFERASE
3cxq:A (ASP83) to (VAL119) CRYSTAL STRUCTURE OF HUMAN GLUCOSAMINE 6-PHOSPHATE N- ACETYLTRANSFERASE 1 BOUND TO GLCN6P | GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE 1, ACYLTRANSFERASE, ENDOSOME, GOLGI APPARATUS, MEMBRANE, TRANSFERASE
3cxs:A (ASP83) to (VAL119) CRYSTAL STRUCTURE OF HUMAN GNA1 | GLUCOSAMINE-6-PHOSPHATE N-ACETYLTRANSFERASE 1, ACYLTRANSFERASE, ENDOSOME, GOLGI APPARATUS, MEMBRANE, TRANSFERASE
4ryc:B (ASP257) to (LEU284) RENIN IN COMPLEXED WITH 4-METHOXY-3-(3-METHOXYPROPOXY)-N-{[(3S,4S)-4- {[(4-METHYLPHENYL)SULFONYL]AMINO}PYRROLIDIN-3-YL]METHYL}-N-(PROPAN-2- YL)BENZAMIDE INHIBITOR | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3d4z:A (PHE804) to (GLN850) GOLGI MANNOSIDASE II COMPLEX WITH GLUCO-IMIDAZOLE | GH38 GLYCOSIDASE, HYDROLASE
3d50:A (PHE804) to (GLN850) GOLGI MANNOSIDASE II COMPLEX WITH N-OCTYL-6-EPI-VALIENAMINE | GH38 GLYCOSIDASE, HYDROLASE
3d51:A (PHE804) to (GLN850) GOLGI MANNOSIDASE II COMPLEX WITH GLUCO-HYDROXYIMINOLACTAM | GH38 GLYCOSIDASE, HYDROLASE
3d52:A (PHE804) to (GLN850) GOLGI MANNOSIDASE II COMPLEX WITH AN N-ARYL CARBAMATE DERIVATIVE OF GLUCO-HYDROXYIMINOLACTAM | GH38 GLYCOSIDASE, GOLGI APPARATUS, HYDROLASE, MEMBRANE, METAL-BINDING, SIGNAL-ANCHOR, TRANSMEMBRANE, ZINC
4cu7:A (ASN157) to (PHE233) UNRAVELLING THE MULTIPLE FUNCTIONS OF THE ARCHITECTURALLY INTRICATE STREPTOCOCCUS PNEUMONIAE BETA-GALACTOSIDASE, BGAA | HYDROLASE
3ddf:A (PHE804) to (GLY849) GOLGI MANNOSIDASE II COMPLEX WITH (3R,4R,5R)-3,4-DIHYDROXY-5-({[(1R)- 2-HYDROXY-1 PHENYLETHYL]AMINO}METHYL) PYRROLIDIN-2-ONE | GH38 GLYCOSIDASE, HYDROLASE
4ttv:A (GLY541) to (LEU594) CRYSTAL STRUCTURE OF HUMAN THRRS COMPLEXING WITH A BIOENGINEERED MACROLIDE BC194 | TRNA, SYNTHETASE, INHIBITOR, MACROLIDE, LIGASE-ANTIBIOTIC COMPLEX
4ttv:C (GLY541) to (LEU594) CRYSTAL STRUCTURE OF HUMAN THRRS COMPLEXING WITH A BIOENGINEERED MACROLIDE BC194 | TRNA, SYNTHETASE, INHIBITOR, MACROLIDE, LIGASE-ANTIBIOTIC COMPLEX
4ttv:D (GLY541) to (LEU594) CRYSTAL STRUCTURE OF HUMAN THRRS COMPLEXING WITH A BIOENGINEERED MACROLIDE BC194 | TRNA, SYNTHETASE, INHIBITOR, MACROLIDE, LIGASE-ANTIBIOTIC COMPLEX
4tw1:P (ASN175) to (ASN206) CRYSTAL STRUCTURE OF THE OCTAMERIC PORE COMPLEX OF THE STAPHYLOCOCCUS AUREUS BI-COMPONENT TOXIN LUKGH | OCTAMER LEUKOCIDIN PORE-FORMING TOXIN, TOXIN
3doh:A (THR109) to (SER146) CRYSTAL STRUCTURE OF A THERMOSTABLE ESTERASE | ALPHA-BETA HYDROLASE, BETA SHEET
3op2:A (GLU7) to (SER53) CRYSTAL STRUCTURE OF PUTATIVE MANDELATE RACEMASE FROM BORDETELLA BRONCHISEPTICA RB50 COMPLEXED WITH 2-OXOGLUTARATE/PHOSPHATE | STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, RACEMASE, 2- OXOGLUTARATE, PSI-2, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, ISOMERASE
3oqk:A (ILE258) to (ALA285) CRYSTAL STRUCTURE ANALYSIS OF RENIN-INDOLE-PIPERAZIN INHIBITOR COMPLEXES | RENIN HUMAN, ASPARTYL PROTEASE, RENIN INHIBITION, HYPERTENSION, HYDROLASE
3dx0:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH MANNOSTATIN A AT PH 5.75 | GH38 GLYCOSIDASE, GLYCOSIDASE, GOLGI APPARATUS, HYDROLASE, MEMBRANE, METAL-BINDING, SIGNAL-ANCHOR, TRANSMEMBRANE
3dx3:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH MANNOSTATIN ANALOG (1R,2R, 3S,4R,5R)-5-AMINOCYCLOPENTANE-1,2,3,4-TETRAOL | GH38 GLYCOSIDASE, GLYCOSIDASE, GOLGI APPARATUS, HYDROLASE, MEMBRANE, METAL-BINDING, SIGNAL-ANCHOR, TRANSMEMBRANE
3dx2:A (PHE804) to (GLY849) GOLGI MANNOSIDASE II COMPLEX WITH MANNOSTATIN B | GH38 GLYCOSIDASE, GLYCOSIDASE, GOLGI APPARATUS, HYDROLASE, MEMBRANE, METAL-BINDING, SIGNAL-ANCHOR, TRANSMEMBRANE, ZINC
3dx4:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH MANNOSTATIN ANALOG (1R,2R, 3R,4S,5R)-4-AMINO-5-METHOXYCYCLOPENTANE-1,2,3-TRIOL | GH38 GLYCOSIDASE, GLYCOSIDASE, GOLGI APPARATUS, HYDROLASE, MEMBRANE, METAL-BINDING, SIGNAL-ANCHOR, TRANSMEMBRANE
5hhv:A (PRO50) to (PRO91) INHIBITING COMPLEX IL-17A AND IL-17RA INTERACTIONS WITH A LINEAR PEPTIDE | IL-17, INFLAMMATION, INHIBITOR, COMPLEX CRYSTAL STRUCTURE, IMMUNE SYSTEM-INHIBITOR COMPLEX
5hi3:A (PRO50) to (GLU95) BINDING SITE ELUCIDATION AND STRUCTURE GUIDED DESIGN OF MACROCYCLIC IL-17A ANTAGONISTS | IL-17A, PSORIASIS, MD SIMULATION, SULFONYL FLUORIDE, INHIBITOR, MACROCYCLE, IMMUNE SYSTEM-INHIBITOR COMPLEX
5hi3:B (PRO50) to (LEU99) BINDING SITE ELUCIDATION AND STRUCTURE GUIDED DESIGN OF MACROCYCLIC IL-17A ANTAGONISTS | IL-17A, PSORIASIS, MD SIMULATION, SULFONYL FLUORIDE, INHIBITOR, MACROCYCLE, IMMUNE SYSTEM-INHIBITOR COMPLEX
5hi4:A (PRO50) to (GLU95) BINDING SITE ELUCIDATION AND STRUCTURE GUIDED DESIGN OF MACROCYCLIC IL-17A ANTAGONISTS | IL-17A, PSORIASIS, MD SIMULATION, SULFONYL FLUORIDE, INHIBITOR, MACROCYCLE, IMMUNE SYSTEM-INHIBITOR COMPLEX
5hi5:B (PRO50) to (LEU99) BINDING SITE ELUCIDATION AND STRUCTURE GUIDED DESIGN OF MACROCYCLIC IL-17A ANTAGONISTS | IL-17A, PSORIASIS, MD SIMULATION, SULFONYL FLUORIDE, INHIBITOR, MACROCYCLE, IMMUNE SYSTEM-INHIBITOR COMPLEX
3dzq:A (ASN620) to (SER649) HUMAN EPHA3 KINASE DOMAIN IN COMPLEX WITH INHIBITOR AWL-II- 38.3 | RECEPTOR TYROSINE KINASE, STRUCTURAL GENOMICS CONSORTIUM, SGC, ATP-BINDING, MEMBRANE, NUCLEOTIDE BINDING, PHOSPHORYLATION, TRANSFERASE, TRANSMEMBRANE, TYROSINE- PROTEIN KINASE, INHIBITOR-COMPLEX, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN
3pay:A (HIS144) to (PRO200) CRYSTAL STRUCTURE OF A PUTATIVE ADHESIN (BACOVA_04077) FROM BACTEROIDES OVATUS AT 2.50 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, CELL ADHESION
3pay:B (HIS144) to (PRO200) CRYSTAL STRUCTURE OF A PUTATIVE ADHESIN (BACOVA_04077) FROM BACTEROIDES OVATUS AT 2.50 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, CELL ADHESION
5i70:A (LEU257) to (LEU287) CRYSTAL STRUCTURE OF PLASMEPSIN IV | PLASMEPSIN, ASPARTIC PROTEASE, MALARIA, CATHEPSIN D LIKE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4uun:A (HIS178) to (LYS207) TRICHOMONAS VAGINALIS LACTATE DEHYDROGENASE IN COMPLEX WITH NADH | OXIDOREDUCTASE
4uum:A (HIS178) to (LYS207) APO TRICHOMONAS VAGINALIS LACTATE DEHYDROGENASE | OXIDOREDUCTASE
3q3t:A (ILE258) to (ALA285) ALKYL AMINE RENIN INHIBITORS: FILLING S1 FROM S3 | ASPARTATE PROTEASE, HYPERTENSION, RENIN INHIBITORS, GLYCOPROTEIN, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3q3t:B (ASP257) to (ALA285) ALKYL AMINE RENIN INHIBITORS: FILLING S1 FROM S3 | ASPARTATE PROTEASE, HYPERTENSION, RENIN INHIBITORS, GLYCOPROTEIN, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3q4b:A (ILE258) to (ALA285) CLINICALLY USEFUL ALKYL AMINE RENIN INHIBITORS | ASPARTATE PROTEASE, HYPERTENSION, RENIN EXPRESSION, RENIN INHIBITOR, ASPARTYL PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, GLYCOPROTEIN, MEMBRANE, PROTEASE, SECRETED, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3q5h:A (ILE258) to (ALA285) CLINICALLY USEFUL ALKYL AMINE RENIN INHIBITORS | ASPARTATE PROTEASE, HYPERTENSION, RENIN EXPRESSION, RENIN INHIBITOR, ASPARTYL PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, GLYCOPROTEIN, MEMBRANE, PROTEASE, SECRETED, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3qar:A (ALA427) to (HIS483) CRYSTAL STRUCTURE OF PI3K-GAMMA IN COMPLEX WITH TRIAZINE-BENZIMIDAZOLE 32 | INHIBITOR, P110, KINASE, TRANSFERASE, ATP-BINDING, P84, P101, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qlb:A (LEU613) to (ASN667) ENANTIOPYOCHELIN OUTER MEMBRANE TONB-DEPENDENT TRANSPORTER FROM PSEUDOMONAS FLUORESCENS BOUND TO THE FERRI-ENANTIOPYOCHELIN | MEMBRANE PROTEIN, TRANSPORT, FERRI-ENANTIOPYOCHELIN, OUTER MEMBRANE, METAL TRANSPORT
4uzn:A (GLY535) to (ALA564) THE NATIVE STRUCTURE OF THE FAMILY 46 CARBOHYDRATE-BINDING MODULE (CBM46) OF ENDO-BETA-1,4-GLUCANASE B (CEL5B) FROM BACILLUS HALODURANS | HYDROLASE
4uzn:B (GLY535) to (ALA564) THE NATIVE STRUCTURE OF THE FAMILY 46 CARBOHYDRATE-BINDING MODULE (CBM46) OF ENDO-BETA-1,4-GLUCANASE B (CEL5B) FROM BACILLUS HALODURANS | HYDROLASE
4w6x:A (SER58) to (SER97) CO-COMPLEX STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF WITH INHIBITORY NANOBODY NBFEDF7 | LECTIN, FIMBRIAE, CELL ADHESION, INHIBITOR
5jea:E (PRO184) to (SER228) STRUCTURE OF A CYTOPLASMIC 11-SUBUNIT RNA EXOSOME COMPLEX INCLUDING SKI7, BOUND TO RNA | EXOSOME, SKI7, NUCLEASE, RNA DEGRADATION, HYDROLASE- RNA COMPLEX, HYDROLASE-RNA COMPLEX
5jmc:C (TYR1122) to (SER1152) RECEPTOR BINDING DOMAIN OF BOTULINUM NEUROTOXIN A IN COMPLEX WITH RAT SV2C | HYDROLASE
4fup:B (GLU138) to (VAL193) STRUCTURAL BASIS FOR ZN2+-DEPENDENT INTERCELLULAR ADHESION IN STAPHYLOCOCCAL BIOFILMS | HYDROPHILIC PROTEIN, NON-GLOBULAR, FREESTANDING BETA SHEET, ZINC DEPENDENT DIMER, MEMBRANE PROTEIN
5ldt:B (ASN57) to (GLY106) CRYSTAL STRUCTURES OF MOMP FROM CAMPYLOBACTER JEJUNI | OUTERMENBRANE PROTEIN, PORIN, MEMBRANE PROTEIN
5ldt:C (ASN57) to (GLY106) CRYSTAL STRUCTURES OF MOMP FROM CAMPYLOBACTER JEJUNI | OUTERMENBRANE PROTEIN, PORIN, MEMBRANE PROTEIN
2omy:B (SER1) to (GLY40) CRYSTAL STRUCTURE OF INLA S192N/HEC1 COMPLEX | LEUCINE-RICH-REPEAT, INVASION PROTEIN, IG-LIKE DOMAIN, ADHESION PROTEIN, CELL INVASION-CELL ADHESION COMPLEX
2q7t:A (ALA121) to (VAL161) CRYSTAL STRUCTURE OF THE F PLASMID TRAI RELAXASE DOMAIN WITH THE SCISSILE THYMIDINE BASE | RELAXASE, HYDROLASE, CONJUGATION
1pkk:B (ALA131) to (TYR156) STRUCTURAL BASIS FOR RECOGNITION AND CATALYSIS BY THE BIFUNCTIONAL DCTP DEAMINASE AND DUTPASE FROM METHANOCOCCUS JANNASCHII | DCTP DEAMINASE, DUTPASE, DCD-DUT, MJ0430, DCTP, DUTP, HYDROLASE
1e4e:B (CYS213) to (VAL260) D-ALANYL-D-LACATE LIGASE | LIGASE, CELL WALL, ANTIBIOTIC RESISTANCE, MEMBRANE, PEPTIDOGLYCAN SYNTHESIS
2r4n:A (PRO43) to (ILE98) CRYSTAL STRUCTURE OF THE LONG-CHAIN FATTY ACID TRANSPORTER FADL MUTANT N33A | BETA BARREL, OUTER MEMBRANE PROTEIN, LIPID TRANSPORT, PHAGE RECOGNITION, TRANSMEMBRANE, TRANSPORT, TRANSPORT PROTEIN
1r33:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH 5-THIO-D-MANNOPYRANOSYLAMINE | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
2f7o:A (PHE804) to (GLY849) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH MANNOSTATIN A | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
2f7q:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH AMINOCYCLOPENTITETROL | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
2f7r:A (PHE804) to (GLN850) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH BENZYL-AMINOCYCLOPENTITETROL | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
1s68:A (SER93) to (TYR132) STRUCTURE AND MECHANISM OF RNA LIGASE | RIBONUCLEIC ACID LIGASE, RNA REPAIR, T4
4kzo:C (GLY150) to (GLN185) CRYSTAL STRUCTURE ANALYSIS OF HUMAN IDH1 MUTANTS IN COMPLEX WITH NADP+ AND CA2+/ALPHA-KETOGLUTARATE | CYTOSOLIC, OXIDOREDUCTASE
3vye:A (ILE268) to (ALA299) HUMAN RENIN IN COMPLEX WITH INHIBITOR 7 | ASPARTYL PROTEASE, RAS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2hvq:A (SER93) to (TYR132) STRUCTURE OF ADENYLATED FULL-LENGTH T4 RNA LIGASE 2 | RNA, LIGASE, LYSINE ADENYLATE, T4
3wau:A (GLY267) to (ALA304) CRYSTAL STRUCTURE OF 4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE MGP COMPLEXED WITH M1P | 5-BLADED BETA PROPELLER FOLD, PHOSPHORYLASE, MANNAN BIODEGRADATION, TRANSFERASE
1k9v:F (GLY454) to (GLN476) STRUCTURAL EVIDENCE FOR AMMONIA TUNELLING ACROSS THE (BETA- ALPHA)8-BARREL OF THE IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE BIENZYME COMPLEX | GLUTAMINASE, IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE, (BETA- ALPHA)8-BARREL, AMMONIA TUNNEL, X-RAY STRUCTURE, TRANSFERASE
1kiu:J (VAL168) to (GLY199) FIMH ADHESIN Q133N MUTANT-FIMC CHAPERONE COMPLEX WITH METHYL-ALPHA-D-MANNOSE | ADHESIN-CHAPERONE COMPLEX, MANNOSE-BOUND, CHAPERONE/CELL ADHESION COMPLEX
1kiu:L (VAL168) to (GLY199) FIMH ADHESIN Q133N MUTANT-FIMC CHAPERONE COMPLEX WITH METHYL-ALPHA-D-MANNOSE | ADHESIN-CHAPERONE COMPLEX, MANNOSE-BOUND, CHAPERONE/CELL ADHESION COMPLEX
1kiu:N (VAL168) to (GLY199) FIMH ADHESIN Q133N MUTANT-FIMC CHAPERONE COMPLEX WITH METHYL-ALPHA-D-MANNOSE | ADHESIN-CHAPERONE COMPLEX, MANNOSE-BOUND, CHAPERONE/CELL ADHESION COMPLEX
1kiu:P (VAL168) to (GLY199) FIMH ADHESIN Q133N MUTANT-FIMC CHAPERONE COMPLEX WITH METHYL-ALPHA-D-MANNOSE | ADHESIN-CHAPERONE COMPLEX, MANNOSE-BOUND, CHAPERONE/CELL ADHESION COMPLEX
2o28:A (ASP83) to (VAL119) CRYSTAL STRUCTURE OF GNPNAT1 | ACETYLTRANSFERASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
2o28:B (ASP83) to (VAL119) CRYSTAL STRUCTURE OF GNPNAT1 | ACETYLTRANSFERASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
4a6a:A (GLY116) to (TRP141) A115V VARIANT OF DCTP DEAMINASE-DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH DTTP | HYDROLASE, DEOXY-RIBONUCLEOTIDE METABOLISM, DTTP INHIBITION
4a6a:B (GLY116) to (TRP141) A115V VARIANT OF DCTP DEAMINASE-DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH DTTP | HYDROLASE, DEOXY-RIBONUCLEOTIDE METABOLISM, DTTP INHIBITION
4a6a:C (GLY116) to (TRP141) A115V VARIANT OF DCTP DEAMINASE-DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH DTTP | HYDROLASE, DEOXY-RIBONUCLEOTIDE METABOLISM, DTTP INHIBITION
4a6a:D (GLY116) to (TRP141) A115V VARIANT OF DCTP DEAMINASE-DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH DTTP | HYDROLASE, DEOXY-RIBONUCLEOTIDE METABOLISM, DTTP INHIBITION
4a6a:E (GLY116) to (TRP141) A115V VARIANT OF DCTP DEAMINASE-DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH DTTP | HYDROLASE, DEOXY-RIBONUCLEOTIDE METABOLISM, DTTP INHIBITION
4a6a:G (GLY116) to (TRP141) A115V VARIANT OF DCTP DEAMINASE-DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH DTTP | HYDROLASE, DEOXY-RIBONUCLEOTIDE METABOLISM, DTTP INHIBITION
4a6a:J (GLY116) to (TRP141) A115V VARIANT OF DCTP DEAMINASE-DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH DTTP | HYDROLASE, DEOXY-RIBONUCLEOTIDE METABOLISM, DTTP INHIBITION
5cyl:H (GLY221) to (ASP259) CRYSTAL STRUCTURE OF THE CUPB6 TIP ADHESIN FROM PSEUDOMONAS AERUGINOSA | BIOFILM, ADHESION, CHAPERONE-USHER, PILIN, CELL ADHESION
4pcg:A (ASP144) to (GLY211) STRUCTURE OF HUMAN POLYOMAVIRUS 6 (HPYV6) VP1 PENTAMER | MAJOR VIRAL CAPSID PROTEIN, JELLY-ROLL TOPOLOGY, ATTACHMENT TO HOST- CELL RECEPTORS, VIRAL PROTEIN
4pcg:C (ASP144) to (GLY211) STRUCTURE OF HUMAN POLYOMAVIRUS 6 (HPYV6) VP1 PENTAMER | MAJOR VIRAL CAPSID PROTEIN, JELLY-ROLL TOPOLOGY, ATTACHMENT TO HOST- CELL RECEPTORS, VIRAL PROTEIN
4pcg:D (ASP144) to (GLY211) STRUCTURE OF HUMAN POLYOMAVIRUS 6 (HPYV6) VP1 PENTAMER | MAJOR VIRAL CAPSID PROTEIN, JELLY-ROLL TOPOLOGY, ATTACHMENT TO HOST- CELL RECEPTORS, VIRAL PROTEIN
4pcg:E (ASP144) to (GLY211) STRUCTURE OF HUMAN POLYOMAVIRUS 6 (HPYV6) VP1 PENTAMER | MAJOR VIRAL CAPSID PROTEIN, JELLY-ROLL TOPOLOGY, ATTACHMENT TO HOST- CELL RECEPTORS, VIRAL PROTEIN
3l6t:A (ALA124) to (PHE164) CRYSTAL STRUCTURE OF AN N-TERMINAL MUTANT OF THE PLASMID PCU1 TRAI RELAXASE DOMAIN | TRWC SUPERFAMILY OF RELAXASE ENZYMES, CONJUGATIVE RELAXASE, MOB CLASS RELAXASE, CONJUGAL NICKASE, HYDROLASE, HISTIDINE TRIAD, HUH+H MOTIF
4q1n:A (ASP257) to (ALA285) STRUCTURE-BASED DESIGN OF 4-HYDROXY-3,5-SUBSTITUTED PIPERIDINES AS DIRECT RENIN INHIBITORS | ASPARTIC PROTEASE, ANGIOTENSIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1zm1:A (GLY67) to (THR106) CRYSTAL STRUCTURES OF COMPLEX F. SUCCINOGENES 1,3-1,4-BETA- D-GLUCANASE AND BETA-1,3-1,4-CELLOTRIOSE | GLUCANASE/1,3-1,4-BETA-D-GLUCANASE, BETA-1,3-1,4-CELLOTRIOSE (CLTR), ACTIVE CLEFT, HYDROLASE
1zm1:B (GLY67) to (THR100) CRYSTAL STRUCTURES OF COMPLEX F. SUCCINOGENES 1,3-1,4-BETA- D-GLUCANASE AND BETA-1,3-1,4-CELLOTRIOSE | GLUCANASE/1,3-1,4-BETA-D-GLUCANASE, BETA-1,3-1,4-CELLOTRIOSE (CLTR), ACTIVE CLEFT, HYDROLASE
3b07:A (SER220) to (ASN266) CRYSTAL STRUCTURE OF OCTAMERIC PORE FORM OF GAMMA-HEMOLYSIN FROM STAPHYLOCOCCUS AUREUS | PROTEIN COMPLEX, TOXIN
3b07:C (SER220) to (ASN266) CRYSTAL STRUCTURE OF OCTAMERIC PORE FORM OF GAMMA-HEMOLYSIN FROM STAPHYLOCOCCUS AUREUS | PROTEIN COMPLEX, TOXIN
3b07:E (SER220) to (ASN266) CRYSTAL STRUCTURE OF OCTAMERIC PORE FORM OF GAMMA-HEMOLYSIN FROM STAPHYLOCOCCUS AUREUS | PROTEIN COMPLEX, TOXIN
3b07:G (SER220) to (ASN266) CRYSTAL STRUCTURE OF OCTAMERIC PORE FORM OF GAMMA-HEMOLYSIN FROM STAPHYLOCOCCUS AUREUS | PROTEIN COMPLEX, TOXIN
3bvw:A (PHE804) to (GLY849) GOLGI MANNOSIDASE II D204A CATALYTIC NUCLEOPHILE MUTANT COMPLEX WITH METHYL (2-DEOXY-2-ACETAMIDO-BETA-D- GLUCOPYRANOSYL)-(1->2)-ALPHA-D-MANNOPYRANOSYL- (1->3)- [ALPHA-D-MANNOPYRANOSYL-(1->6)-6-THIO-ALPHA-D- MANNOPYRANOSYL- (1->6)]-BETA-D-MANNOPYRANOSIDE | FAMILY 38 GLYCOYSL HYDROLASE, GLYCOSIDASE, GOLGI APPARATUS, MEMBRANE, SIGNAL-ANCHOR, TRANSMEMBRANE
3cqf:B (LYS466) to (GLY500) CRYSTAL STRUCTURE OF ANTHROLYSIN O (ALO) | ANTHROLYSIN O, X-RAY CRYSTALLOGRAPHY, CYTOLYSIN, ANTHRAX, TOXIN
5fxi:A (PHE369) to (ASN396) GLUN1B-GLUN2B NMDA RECEPTOR STRUCTURE IN NON-ACTIVE-2 | TRANSPORT PROTEIN, SIGNALING PROTEIN, NMDA RECEPTOR, GLUTAMATE RECEPTOR, GLUN1, GLUN2B, ION CHANNEL
5fxi:C (PHE369) to (ASN396) GLUN1B-GLUN2B NMDA RECEPTOR STRUCTURE IN NON-ACTIVE-2 | TRANSPORT PROTEIN, SIGNALING PROTEIN, NMDA RECEPTOR, GLUTAMATE RECEPTOR, GLUN1, GLUN2B, ION CHANNEL
3ddg:A (PHE804) to (GLN850) GOLGI MANNOSIDASE II COMPLEX WITH (3R,4R,5R)-3,4-DIHYDROXY-5-({[(1R)- 2-HYDROXY-1 PHENYLETHYL]AMINO}METHYL) METHYLPYRROLIDIN-2-ONE | GH38 GLYCOSIDASE, HYDROLASE
5h4z:B (GLY188) to (GLU228) CRYSTAL STRUCTURE OF S202G MUTANT OF HUMAN SYT-5 C2A DOMAIN | METAL BINDING PROTEIN, MUTANT
4e6f:A (LEU117) to (LYS149) CRYSTAL STRUCTURE OF A DUF4468 FAMILY PROTEIN (BACOVA_04320) FROM BACTEROIDES OVATUS ATCC 8483 AT 1.49 A RESOLUTION | PF14730 FAMILY PROTEIN, DUF4468 WITH TBP-LIKE FOLD,STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, UNKNOWN FUNCTION
4e6f:B (THR116) to (LYS149) CRYSTAL STRUCTURE OF A DUF4468 FAMILY PROTEIN (BACOVA_04320) FROM BACTEROIDES OVATUS ATCC 8483 AT 1.49 A RESOLUTION | PF14730 FAMILY PROTEIN, DUF4468 WITH TBP-LIKE FOLD,STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, UNKNOWN FUNCTION
3pvk:A (VAL262) to (PHE298) SECRETED ASPARTIC PROTEASE 2 IN COMPLEX WITH BENZAMIDINE | HYDROLASE
5jod:A (LEU257) to (LEU287) STRUCTURE OF PROPLASMEPSIN IV FROM PLASMODIUM FALCIPARUM | MALARIA, HYDROLASE
5jod:B (LEU257) to (TYR288) STRUCTURE OF PROPLASMEPSIN IV FROM PLASMODIUM FALCIPARUM | MALARIA, HYDROLASE
4gdi:B (ARG419) to (ASP459) A SUBTYPE N10 NEURAMINIDASE-LIKE PROTEIN OF A/LITTLE YELLOW-SHOULDERED BAT/GUATEMALA/164/2009 | INFLUENZA VIRUS, NEURAMINIDASE-LIKE, N10, BETA-PROPELLER, ECTODOMAIN, VIRAL PROTEIN
4gdi:D (CYS417) to (ASP459) A SUBTYPE N10 NEURAMINIDASE-LIKE PROTEIN OF A/LITTLE YELLOW-SHOULDERED BAT/GUATEMALA/164/2009 | INFLUENZA VIRUS, NEURAMINIDASE-LIKE, N10, BETA-PROPELLER, ECTODOMAIN, VIRAL PROTEIN
4gdi:F (LEU424) to (ASP459) A SUBTYPE N10 NEURAMINIDASE-LIKE PROTEIN OF A/LITTLE YELLOW-SHOULDERED BAT/GUATEMALA/164/2009 | INFLUENZA VIRUS, NEURAMINIDASE-LIKE, N10, BETA-PROPELLER, ECTODOMAIN, VIRAL PROTEIN
4gj6:B (ASP257) to (ALA285) CRYSTAL STRUCTURE OF RENIN IN COMPLEX WITH NVP-AYZ832 (COMPOUND 6A) | RENIN INHIBITOR, PHARMACOPHORE SEARCH, TRANS-3,4-DISUBSTITUTED PYRROLIDINE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX