1n8w:B (PRO115) to (GLY144) BIOCHEMICAL AND STRUCTURAL STUDIES OF MALATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS | MALATE SYNTHASE, GLYOXYLATE PATHWAY, MYCOBACTERIUM TUBERCULOSIS, MALATE, COENZYME A, GLCB, GLYOXYLATE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, LYASE
3roa:B (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 6- ETHYL-5-[(3R)-3-[3-METHOXY-5-(MORPHOLIN-4-YL)PHENYL]BUT-1-YN-1- YL]PYRIMIDINE-2,4-DIAMINE (UCP1004) | ANTIFUNGAL AGENTS, CANDIDA GLABRATA, DRUG DESIGN, ENZYME INHIBITORS, FUNGAL PROTEINS, MODELS, MOLECULAR STRUCTURE, STRUCTURE-ACTIVITY RELATIONSHIP, TETRAHYDROFOLATE DEHYDROGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3eej:A (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH 2,4-DIAMINO-5- [3-METHYL-3-(3-METHOXY-5-PHENYLPHENYL)PROP-1-YNYL]-6- METHYLPYRIMIDINE(UCP111D) AND NADPH | ENZYME, OXIDOREDUCTASE
3eej:B (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH 2,4-DIAMINO-5- [3-METHYL-3-(3-METHOXY-5-PHENYLPHENYL)PROP-1-YNYL]-6- METHYLPYRIMIDINE(UCP111D) AND NADPH | ENZYME, OXIDOREDUCTASE
3eek:A (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH 2,4-DIAMINO-5- [3-METHYL-3-(3-METHOXY-5-(4-METHYLPHENYL)PHENYL)PROP-1-YNYL]-6- METHYLPYRIMIDINE(UCP111D4M) AND NADPH | ENZYME, OXIDOREDUCTASE
3eek:B (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH 2,4-DIAMINO-5- [3-METHYL-3-(3-METHOXY-5-(4-METHYLPHENYL)PHENYL)PROP-1-YNYL]-6- METHYLPYRIMIDINE(UCP111D4M) AND NADPH | ENZYME, OXIDOREDUCTASE
3eel:B (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH 2,4-DIAMINO-5- [3-METHYL-3-(3-METHOXY-5-(3,5-DIMETHYLPHENYL)PHENYL)PROP-1-YNYL]-6- METHYLPYRIMIDINE(UCP11153TM) AND NADPH | ENZYME, OXIDOREDUCTASE
3eem:A (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH 2,4-DIAMINO-5- [3-METHYL-3-(3-METHOXY-5-(2,6-DIMETHYLPHENYL)PHENYL)PROP-1-YNYL]-6- METHYLPYRIMIDINE(UCP111D26M) AND NADPH | ENZYME, OXIDOREDUCTASE
4wkg:F (VAL390) to (GLY437) THE CRYSTAL STRUCTURE OF APO ARNA FEATURES AN UNEXPECTED CENTRAL BINDING POCKET AND PROVIDES AN EXPLANATION FOR ENZYMATIC COOP- ERATIVITY | ARNA, MULTI-DRUG RESISTANCE, MDR, POLYMYXIN, DEHYDROGENASE, TRANSFORMYLASE, COOPERATIVITY, ALLOSTERIC REGULATION, TRANSFERASE
4h2a:A (VAL501) to (ASN570) CRYSTAL STRUCTURE OF WILD TYPE PROTECTIVE ANTIGEN TO 1.62 A (PH 7.5) | TOXIN DELIVERY, METAL ION BINDING, PROTEIN BINDING, EXTRACELLULAR REGION, TOXIN
2oz5:B (ARG26) to (ARG64) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PROTEIN TYROSINE PHOSPHATASE PTPB IN COMPLEX WITH THE SPECIFIC INHIBITOR OMTS | PROTEIN TYROSINE PHOSPHATASE IN COMPLEX WITH SMALL MOLECULE INHIBITOR, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, UNKNOWN FUNCTION
3s1a:B (LYS102) to (VAL150) CRYSTAL STRUCTURE OF THE PHOSPHORYLATION-SITE DOUBLE MUTANT S431E/T432E OF THE KAIC CIRCADIAN CLOCK PROTEIN | HEXAMER, ATP BINDING, AUTO-KINASE, PHOPHATASE, SERINE THREONINE KINASE, MG BINDING, PHOSPHORYLATION, TRANSFERASE
2p4g:A (GLU34) to (ASN86) CRYSTAL STRUCTURE OF A PYRIMIDINE REDUCTASE-LIKE PROTEIN (DIP1392) FROM CORYNEBACTERIUM DIPHTHERIAE NCTC AT 2.30 A RESOLUTION | PYRIMIDINE REDUCTASE-LIKE PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, OXIDOREDUCTASE
4hdk:B (CYS123) to (CYS187) CRYSTAL STRUCTURE OF ARSAB IN COMPLEX WITH PHLOROGLUCINOL | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4hdm:A (GLY126) to (GLY194) CRYSTAL STRUCTURE OF ARSAB IN COMPLEX WITH P-CRESOL | TRANSFERASE, TRANSFERASE-SUBSTRATE COMPLEX
4hdn:A (GLY126) to (PHE192) CRYSTAL STRUCTURE OF ARSAB IN THE SUBSTRATE-FREE STATE. | TRANSFERASE
4hdr:A (GLY126) to (PHE192) CRYSTAL STRUCTURE OF ARSAB IN COMPLEX WITH 5,6-DIMETHYLBENZIMIDAZOLE | TRANSFERASE
4hdr:C (GLY126) to (PHE192) CRYSTAL STRUCTURE OF ARSAB IN COMPLEX WITH 5,6-DIMETHYLBENZIMIDAZOLE | TRANSFERASE
4hdr:D (CYS123) to (CYS187) CRYSTAL STRUCTURE OF ARSAB IN COMPLEX WITH 5,6-DIMETHYLBENZIMIDAZOLE | TRANSFERASE
3eye:A (LEU8) to (ASP44) CRYSTAL STRUCTURE OF PTS SYSTEM N-ACETYLGALACTOSAMINE- SPECIFIC IIB COMPONENT 1 FROM ESCHERICHIA COLI | STRUCTURAL GENOMICS, PHOSPHOTRANSFERASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
1ble:A (LEU6) to (ASP41) PHOSPHOENOLPYRUVATE-DEPENDENT PHOSPHOTRANSFERASE SYSTEM | PHOSPHOTRANSFERASE, SUGAR TRANSPORT
1o59:A (MSE1) to (GLY31) CRYSTAL STRUCTURE OF ALLANTOICASE (YIR029W) FROM SACCHAROMYCES CEREVISIAE AT 2.40 A RESOLUTION | YIR029W, ALLANTOICASE, STRUCTURAL GENOMICS, JCSG, PSI, PROTEIN STRUCTURE INITIATIVE, JOINT CENTER FOR STRUCTURAL GENOMICS, HYDROLASE
4hoe:B (VAL6) to (ILE62) CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 5- [3-(2,5-DIMETHOXY-4-PHENYLPHENYL)BUT-1-YN-1-YL]-6-METHYLPYRIMIDINE-2, 4-DIAMINE (UCP111E) | ANTIFUNGAL AGENTS, CANDIDA ALBICANS, DRUG DESIGN, ENZYME INHIBITORS, FUNGAL PROTEINS, STRUCTURE-ACTIVITY RELATIONSHIP, TETRAHYDROFOLATE DEHYDROGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4hof:B (ASN5) to (SER61) CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 5- [3-(2-METHOXY-4-PHENYLPHENYL)BUT-1-YN-1-YL]-6-METHYLPYRIMIDINE-2,4- DIAMINE (UCP111H) | ANTIFUNGAL AGENTS, CANDIDA ALBICANS, DRUG DESIGN, ENZYME INHIBITORS, FUNGAL PROTEINS, STRUCTURE-ACTIVITY RELATIONSHIP, TETRAHYDROFOLATE DEHYDROGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4hog:A (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 5- [3-(2-METHOXY-4-PHENYLPHENYL)BUT-1-YN-1-YL]-6-METHYLPYRIMIDINE-2,4- DIAMINE (UCP111H) | ANTIFUNGAL AGENTS, CANDIDA GLABRATA, DRUG DESIGN, ENZYME INHIBITORS, FUNGAL PROTEINS, STRUCTURE-ACTIVITY RELATIONSHIP, TETRAHYDROFOLATE DEHYDROGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3f91:A (LEU4) to (ILE60) STRUCTURAL DATA FOR HUMAN ACTIVE SITE MUTANT ENZYME COMPLEXES | ACTIVE SITE MUTANTS LIGAND COMPLEX DHFR, NADP, ONE-CARBON METABOLISM, OXIDOREDUCTASE
3f99:A (ARG255) to (ASN293) W354F YERSINIA ENTEROCOLITICA PTPASE APO FORM | HYDROLASE, P-LOOP, WPD-LOOP, PTP, PROTEIN PHOSPHATASE, APOENZYME, APO STRUCTURE OF THE W354F YOPH MUTANT, MEMBRANE, OUTER MEMBRANE, SECRETED, VIRULENCE
3f9a:A (ARG255) to (ASN293) W354F YERSINIA ENTEROCOLITICA PTPASE COMPLEXED WITH TUNGSTATE | HYDROLASE, P-LOOP, WPD-LOOP, PROTEIN PHOSPHATASE, TUNGSTATE, MEMBRANE, OUTER MEMBRANE, SECRETED, VIRULENCE
3f9b:A (ARG255) to (ASN293) W354F YERSINIA ENTEROCOLITICA PTPASE COMPLEXED WITH DIVANADATE | HYDROLASE, P-LOOP, WPD-LOOP, PTP, PROTEIN PHOSPHATASE, VANADATE, DIVANADATE, MEMBRANE, OUTER MEMBRANE, SECRETED, VIRULENCE
3s9i:A (PRO115) to (GLY144) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 2-4-DIOXO-4-PHENYLBUTANOIC ACID INHIBITOR | INHIBITOR COMPLEX, STRUCTURAL GENOMICS, MYCOBACTERIUM TUBERCULOSIS STRUCTURAL PROTEOMICS PROJECT, XMTB, MALATE SYNTHASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3sad:A (PRO115) to (ASP146) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 4-(2-MEHTYLPHENYL)-2,4-DIOXOBUTANOIC ACID INHIBITOR | INHIBITOR COMPLEX, STRUCTURAL GENOMICS, MYCOBACTERIUM TUBERCULOSIS STRUCTURAL PROTEOMICS PROJECT, XMTB, MALATE SYNTHASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3saz:A (PRO115) to (THR145) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 4-(3-BROMOPHENYL)-2,4-DIOXOBUTANOIC ACID INHIBITOR | INHIBITOR COMPLEX, STRUCTURAL GENOMICS, MYCOBACTERIUM TUBERCULOSIS STRUCTURAL PROTEOMICS PROJECT, XMTB, MALATE SYNTHASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3sb0:A (PRO115) to (GLY144) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 4-(2-CHLORO-6-FLUORO-3-METHYLPHENYL)-2,4-DIOXOBUTANOIC ACID INHIBITOR | INHIBITOR COMPLEX, STRUCTURAL GENOMICS, MYCOBACTERIUM TUBERCULOSIS STRUCTURAL PROTEOMICS PROJECT, XMTB, MALATE SYNTHASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3fd6:A (HIS261) to (GLY307) CRYSTAL STRUCTURE OF HUMAN SELENOPHOSPHATE SYNTHETASE 1 COMPLEX WITH ADP AND PHOSPHATE | SELENOPHOSPHATE SYNTHETASE 1, SELD, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, SELENIUM, TRANSFERASE
4i14:A (GLU29) to (GLY70) CRYSTAL STRUCTURE OF MTB-RIBA2 (RV1415) | DHBPS, GCHII, RIBA2, GTP, RIBOFLAVIN, ANTIMICROBIAL, HYDROLASE, LYASE
4i14:B (ASN30) to (GLY70) CRYSTAL STRUCTURE OF MTB-RIBA2 (RV1415) | DHBPS, GCHII, RIBA2, GTP, RIBOFLAVIN, ANTIMICROBIAL, HYDROLASE, LYASE
1cd2:A (SER6) to (ILE65) LIGAND INDUCED CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURES OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE COMPLEXES WITH FOLATE AND NADP+ | OXIDOREDUCTASE, ONE-CARBON METABOLISM
3fs6:A (LEU4) to (ILE60) CORRELATIONS OF INHIBITOR KINETICS FOR PNEUMOCYSTIS JIROVECII AND HUMAN DIHYDROFOLATE REDUCTASE WITH STRUCTURAL DATA FOR HUMAN ACTIVE SITE MUTANT ENZYME COMPLEXES | HUMAN WILD TYPE DHFR ACTIVE SITE INHIBITORS, NADP, ONE-CARBON METABOLISM, OXIDOREDUCTASE
2q7u:B (MET1001) to (GLY1042) CRYSTAL STRUCTURE OF THE F PLASMID TRAI RELAXASE DOMAIN WITH THE SCISSILE THYMIDINE BASE AND IMIDODIPHOSPHATE | RELAXASE, HYDROLASE, CONJUGATION, ALTERNATIVE INITIATION, ATP-BINDING, DNA-BINDING, HELICASE, NUCLEOTIDE-BINDING, PLASMID
1d0v:A (LYS109) to (GLY192) CRYSTAL STRUCTURE OF NICOTINATE MONONUCLEOTIDE:5,6- DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE (COBT) FROM SALMONELLA TYPHIMURIUM COMPLEXED WITH ITS REACTION PRODUCTS DETERMINED TO 1.9 A RESOLUTION | DINUCLEOTIDE-BINDING MOTIF, PHOSPHORIBOSYLTRANSFERASE, TRANSFERASE
1p7t:A (PRO115) to (SER145) STRUCTURE OF ESCHERICHIA COLI MALATE SYNTHASE G:PYRUVATE:ACETYL- COENZYME A ABORTIVE TERNARY COMPLEX AT 1.95 ANGSTROM RESOLUTION | TIM BARREL, GLYOXYLATE CYCLE, ACETYL-COA, CYSTEINE-SULFENIC ACID, LYASE
1del:B (LEU3) to (THR51) DEOXYNUCLEOSIDE MONOPHOSPHATE KINASE COMPLEXED WITH DEOXY-GMP AND AMP | TRANSFERASE, PHOSPHOTRANSFERASE
4xt5:A (GLY38) to (GLY92) CRYSTAL STRUCTURE OF RV2671 FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH NADP+ | REDUCTASE, COFACTOR, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, OXIDOREDUCTASE
4xt8:A (GLY38) to (GLY92) CRYSTAL STRUCTURE OF RV2671 FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH NADP+ AND TRIMETREXATE | TRIMETREXATE, REDUCTASE, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, OXIDOREDUCTASE
1dr1:A (SER3) to (SER59) 2.2 ANGSTROMS CRYSTAL STRUCTURE OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADP+ AND BIOPTERIN | OXIDOREDUCTASE
1dr2:A (LEU4) to (SER59) 2.3 ANGSTROMS CRYSTAL STRUCTURE OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXED WITH THIONADP+ AND BIOPTERIN | OXIDOREDUCTASE
3ghc:A (LEU4) to (ILE60) DESIGN, SYNTHESIS, AND X-RAY CRYSTAL STRUCTURE OF CLASSICAL AND NONCLASSICAL 2-AMINO-4-OXO-5-SUBSTITUTED-6-THIENO[2,3- D]PYRIMIDINES AS DUAL THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE INHIBITORS AND AS POTENTIAL ANTITUMOR AGENST | PROTEIN INHIBITOR COMPLEX FOLATE ANALOGUES, NADP, ONE-CARBON METABOLISM, OXIDOREDUCTASE
4y33:B (ARG271) to (SER305) CRYSTAL OF NO66 IN COMPLEX WITH NI(II)AND N-OXALYLGLYCINE (NOG) | COMPLEX, RIBOSOMAL OXYGENASE, OXIDOREDUCTASE
1pvw:A (GLY27) to (LEU66) 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE FROM M. JANNASCHII | RIBOFLAVIN BIOSYNTHESIS, ISOMERASE
1pvw:C (GLY27) to (LEU66) 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE FROM M. JANNASCHII | RIBOFLAVIN BIOSYNTHESIS, ISOMERASE
1pvy:A (GLY27) to (LEU66) 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE FROM M. JANNASCHII IN COMPLEX WITH RIBULOSE 5-PHOSPHATE | RIBOFLAVIN BIOSYNTHESIS, ISOMERASE
1pvy:B (GLY27) to (LEU66) 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE FROM M. JANNASCHII IN COMPLEX WITH RIBULOSE 5-PHOSPHATE | RIBOFLAVIN BIOSYNTHESIS, ISOMERASE
2r84:B (ASP47) to (GLY77) CRYSTAL STRUCTURE OF PURP FROM PYROCOCCUS FURIOSUS COMPLEXED WITH AMP AND AICAR | ATP-GRASP SUPERFAMILY, UNKNOWN FUNCTION
2r87:A (ASP47) to (GLY77) CRYSTAL STRUCTURE OF PURP FROM PYROCOCCUS FURIOSUS COMPLEXED WITH ADP | ATP-GRASP SUPERFAMILY, UNKNOWN FUNCTION
4yaa:A (ARG255) to (ASN293) YOPH W354Y YERSINIA ENTEROCOLITICA PTPASE APO FORM | PHOSPHATASE, PTP, HYDROLASE
1qcn:B (PRO708) to (GLU743) CRYSTAL STRUCTURE OF FUMARYLACETOACETATE HYDROLASE | MIXED BETA SANDWICH ROLL, HYDROLASE
2e0z:A (ILE214) to (LEU260) CRYSTAL STRUCTURE OF VIRUS-LIKE PARTICLE FROM PYROCOCCUS FURIOSUS | VIRUS-LIKE PARTICLE, VIRUS, BACTERIOPHAGE, HK97, T4, VIRUS LIKE PARTICLE
2ris:A (GLU30) to (GLU71) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE OF CANDIDA ALBICANS- ALTERNATE INTERPRETATION | ALTERNATE MODEL, MAGNESIUM, MANGANESE, METAL-BINDING, RIBOFLAVIN BIOSYNTHESIS, ISOMERASE
2riu:A (GLU32) to (GLU71) ALTERNATIVE MODELS FOR TWO CRYSTAL STRUCTURES OF CANDIDA ALBICANS 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE- ALTERNATE INTERPREATION | ALTERNATE MODEL, MAGNESIUM, MANGANESE, METAL-BINDING, RIBOFLAVIN BIOSYNTHESIS, ISOMERASE
1qsm:A (ASN91) to (LEU137) HISTONE ACETYLTRANSFERASE HPA2 FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH ACETYL COENZYME A | PROTEIN-ACETYL COENZYME A COMPLEX, ACETYLTRANSFERASE, TRANSFERASE
3u96:A (ARG255) to (ASN293) CRYSTAL STRUCTURE OF YOPHQ357F(CATALYTIC DOMAIN, RESIDUES 163-468) IN COMPLEX WITH PNCS | YOPH, PTPASE, HYDROLASE
2eqa:A (LEU40) to (VAL78) CRYSTAL STRUCTURE OF THE HYPOTHETICAL SUA5 PROTEIN FROM SULFOLOBUS TOKODAII | YRDC/RIBB FOLD, YRDC DOMAIN, SUA5 DOMAIN, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, RNA BINDING PROTEIN
1g57:A (GLU38) to (ASP79) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE | DIHYDROXYBUTANONE PHOSPHATE SYNTHASE, RIBOFLAVINE BIOSYNTHESIS, SKELETAL REARRANGEMENT, ANTIMICROBIAL TARGET, STRUCTURE-BASED DESIGN, ISOMERASE
1g57:B (ASN39) to (ASP79) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE | DIHYDROXYBUTANONE PHOSPHATE SYNTHASE, RIBOFLAVINE BIOSYNTHESIS, SKELETAL REARRANGEMENT, ANTIMICROBIAL TARGET, STRUCTURE-BASED DESIGN, ISOMERASE
1g58:A (ASN39) to (ASP79) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE GOLD DERIVATIVE | DIHYDROXYBUTANONE PHOSPHATE SYNTHASE, RIBOFLAVIN BIOSYNTHESIS, SKELETAL REARRANGEMENT, ANTIMICROBIAL TARGET, STRUCTURE-BASED DESIGN, ISOMERASE
1g58:B (ASN39) to (ASP79) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE GOLD DERIVATIVE | DIHYDROXYBUTANONE PHOSPHATE SYNTHASE, RIBOFLAVIN BIOSYNTHESIS, SKELETAL REARRANGEMENT, ANTIMICROBIAL TARGET, STRUCTURE-BASED DESIGN, ISOMERASE
4z6b:A (ARG255) to (ASN293) YOPH W354H YERSINIA ENTEROCOLITICA PTPASE IN THE APO FORM | PHOSPHATASE, YERSINIA, PTP, HYDROLASE
4kqf:A (VAL126) to (GLY192) CRYSTAL STRUCTURE OF COBT E174A COMPLEXED WITH ADENINE | TRANSFERASE
4kqg:A (VAL126) to (GLY192) CRYSTAL STRUCTURE OF COBT E174A COMPLEXED WITH DMB | TRANSFERASE
1snn:A (GLY27) to (LEU66) 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE FROM METHANOCOCCUS JANNASCHII | RIBOFLAVIN BIOSYNTHESIS, ISOMERASE
1snn:B (GLY27) to (LEU66) 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE FROM METHANOCOCCUS JANNASCHII | RIBOFLAVIN BIOSYNTHESIS, ISOMERASE
4zi4:A (ARG255) to (ASN293) YOPH W354H YERSINIA ENTEROCOLITICA PTPASE BOND WITH DIVANADATE GLYCEROL ESTER IN THE ACTIVE SITE | PHOSPHATASE, YERSINIA, PTP, HYDROLASE
4kya:A (PRO4) to (MET87) CRYSTAL STRUCTURE OF NON-CLASSICAL TS INHIBITOR 3 IN COMPLEX WITH TOXOPLASMA GONDII TS-DHFR | SYNTHASE, BIFUNCTIONAL, CHIMERA PROTEIN, OXIDOREDUCTASE, TRANSFERASE- INHIBITOR COMPLEX
2gd9:B (ILE10) to (TRP60) CRYSTAL STRUCTURE OF A PUTATIVE DIHYDROFOLATE REDUCTASE (BSU40760, YYAP) FROM BACILLUS SUBTILIS AT 2.30 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, OXIDOREDUCTASE
3ven:A (ARG423) to (LEU464) CRYSTAL STRUCTURE OF THE O-CARBAMOYLTRANSFERASE TOBZ | ANTIBIOTIC BIOSYNTHESIS, SUBSTRATE ASSISTED CATALYSIS, SUBSTRATE CHANNELING, ADENYLATION, STRUCTURAL ENZYMOLOGY, ENZYME EVOLUTION, TRANSFERASE
3ver:A (ARG423) to (LEU464) CRYSTAL STRUCTURE OF THE O-CARBAMOYLTRANSFERASE TOBZ IN COMPLEX WITH CARBAMOYL ADENYLATE INTERMEDIATE | ANTIBIOTIC BIOSYNTHESIS, SUBSTRATE ASSISTED CATALYSIS, SUBSTRATE CHANNELING, ADENYLATION, STRUCTURAL ENZYMOLOGY, ENZYME EVOLUTION, TRANSFERASE
3ves:A (ARG423) to (LEU464) CRYSTAL STRUCTURE OF THE O-CARBAMOYLTRANSFERASE TOBZ IN COMPLEX WITH AMPCPP AND CARBAMOYL PHOSPHATE | ANTIBIOTIC BIOSYNTHESIS, SUBSTRATE ASSISTED CATALYSIS, SUBSTRATE CHANNELING, ADENYLATION, STRUCTURAL ENZYMOLOGY, ENZYME EVOLUTION, TRANSFERASE
3vew:A (ARG423) to (LEU464) CRYSTAL STRUCTURE OF THE O-CARBAMOYLTRANSFERASE TOBZ IN COMPLEX WITH ADP | ANTIBIOTIC BIOSYNTHESIS, SUBSTRATE ASSISTED CATALYSIS, SUBSTRATE CHANNELING, ADENYLATION, STRUCTURAL ENZYMOLOGY, ENZYME EVOLUTION, TRANSFERASE
3vex:A (ARG423) to (LEU464) CRYSTAL STRUCTURE OF THE O-CARBAMOYLTRANSFERASE TOBZ H14N VARIANT IN COMPLEX WITH CARBAMOYL ADENYLATE INTERMEDIATE | ANTIBIOTIC BIOSYNTHESIS, SUBSTRATE ASSISTED CATALYSIS, SUBSTRATE CHANNELING, ADENYLATION, STRUCTURAL ENZYMOLOGY, ENZYME EVOLUTION, TRANSFERASE
3vez:A (ARG423) to (LEU464) CRYSTAL STRUCTURE OF THE O-CARBAMOYLTRANSFERASE TOBZ K443A VARIANT IN COMPLEX WITH ATP, ADP AND CARBAMOYL PHOSPHATE | ANTIBIOTIC BIOSYNTHESIS, SUBSTRATE ASSISTED CATALYSIS, SUBSTRATE CHANNELING, ADENYLATION, STRUCTURAL ENZYMOLOGY, ENZYME EVOLUTION, TRANSFERASE
3vf4:A (ARG423) to (LEU464) CRYSTAL STRUCTURE OF THE O-CARBAMOYLTRANSFERASE TOBZ S530A VARIANT IN COMPLEX WITH CARBAMOYL PHOSPHATE AND ADP | ANTIBIOTIC BIOSYNTHESIS, SUBSTRATE ASSISTED CATALYSIS, SUBSTRATE CHANNELING, ADENYLATION, STRUCTURAL ENZYMOLOGY, ENZYME EVOLUTION, TRANSFERASE
3vf2:A (ARG423) to (LEU464) CRYSTAL STRUCTURE OF THE O-CARBAMOYLTRANSFERASE TOBZ M473I VARIANT IN COMPLEX WITH CARBAMOYL PHOSPHATE AND ADP | ANTIBIOTIC BIOSYNTHESIS, SUBSTRATE ASSISTED CATALYSIS, SUBSTRATE CHANNELING, ADENYLATION, STRUCTURAL ENZYMOLOGY, ENZYME EVOLUTION, TRANSFERASE
4zn5:A (ARG255) to (ASN293) YOPH W354Y YERSINIA ENTEROCOLITICA PTPASE BOND WITH DIVANADATE GLYCEROL ESTER IN THE ACTIVE SITE | INHIBITOR, PHOSPHATASE, HYDROLASE-INHIBITOR COMPLEX
1t6b:X (VAL501) to (ASN570) CRYSTAL STRUCTURE OF B. ANTHRACIS PROTECTIVE ANTIGEN COMPLEXED WITH HUMAN ANTHRAX TOXIN RECEPTOR | BACILLUS ANTHRACIS; ANTHRAX TOXIN; X-RAY CRYSTALLOGRAPHY, MEMBRANE PROTEIN-TOXIN COMPLEX
1tku:B (GLU32) to (GLU71) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE OF CANDIDA ALBICANS IN COMPLEX WITH RIBULOSE-5-PHOSPHATE | CANDIDA ALBICANS, RIBOFLAVIN BIOSYNTHESIS, 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE, SYNTHETIC GENE, ISOMERASE
1hru:B (GLY232) to (ILE272) THE STRUCTURE OF THE YRDC GENE PRODUCT FROM E.COLI | PROTEIN FOLDING, STRUCTURAL GENOMICS, RNA, SUA5, YRDC, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
3vti:A (GLY225) to (TYR265) CRYSTAL STRUCTURE OF HYPE-HYPF COMPLEX | TRANSFERASE, CARBAMOYLTRANSFER, MATURATION OF [NIFE]-HYDROGENASE, NITRILE SYNTHESIS, IRON, ATP-DEPENDENT DEHYDRATION
1hyo:B (PRO708) to (GLU743) CRYSTAL STRUCTURE OF FUMARYLACETOACETATE HYDROLASE COMPLEXED WITH 4-(HYDROXYMETHYLPHOSPHINOYL)-3-OXO-BUTANOIC ACID | BETA-SANDWICH ROLL, HYDROLASE
1j33:A (GLY112) to (LEU179) CRYSTAL STRUCTURE OF COBT FROM THERMUS THERMOPHILUS HB8 | PHOSPHORIBOSYLTRANSFERASE, COBALAMIN BIOSYNTHESIS, VITAMIN B12, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
3wn6:A (ASP142) to (SER209) CRYSTAL STRUCTURE OF ALPHA-AMYLASE AMYI-1 FROM ORYZA SATIVA | (ALPHA/BETA)8-BARREL, HYDROLASE, CARBOHYDRATE/SUGAR BINDING, GLYCOSYLATION
3wn6:B (ASP142) to (SER209) CRYSTAL STRUCTURE OF ALPHA-AMYLASE AMYI-1 FROM ORYZA SATIVA | (ALPHA/BETA)8-BARREL, HYDROLASE, CARBOHYDRATE/SUGAR BINDING, GLYCOSYLATION
3wn6:C (ASP142) to (SER209) CRYSTAL STRUCTURE OF ALPHA-AMYLASE AMYI-1 FROM ORYZA SATIVA | (ALPHA/BETA)8-BARREL, HYDROLASE, CARBOHYDRATE/SUGAR BINDING, GLYCOSYLATION
3wn6:D (ASP142) to (SER209) CRYSTAL STRUCTURE OF ALPHA-AMYLASE AMYI-1 FROM ORYZA SATIVA | (ALPHA/BETA)8-BARREL, HYDROLASE, CARBOHYDRATE/SUGAR BINDING, GLYCOSYLATION
1vdm:L (LYS3) to (LEU38) CRYSTAL STRUCTURE OF PURINE PHOSPHORIBOSYLTRANSFERASE FROM PYROCOCCUS HORIKOSHII OT3 | PURINE PHOSPHORIBOSYLTRANSFERASE, PYROCOCCUS HORIKOSHII, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
1jho:A (LYS109) to (GLY192) THREE-DIMENSIONAL STRUCTURE OF COBT IN COMPLEX WITH THE REACTION PRODUCTS OF 5-METHYLBENZIMIDAZOLE AND NAMN | COBT, COBALAMIN BIOSYNTHESIS, LOWER LIGAND, COBAMIDES, NN:DBI PRT, N1-ALPHA-PHOSPHORIBOSYLTRANSFERASE, TRANSFERASE
1vj3:A (SER6) to (ILE65) STRUCTURAL STUDIES ON BIO-ACTIVE COMPOUNDS. CRYSTAL STRUCTURE AND MOLECULAR MODELING STUDIES ON THE PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE COFACTOR COMPLEX WITH TAB, A HIGHLY SELECTIVE ANTIFOLATE. | TAB, NADPH, MOLECULAR MODELING, OXIDOREDUCTASE
1vsq:C (LEU166) to (THR202) SOLUTION NMR STRUCTURE OF THE PRODUCTIVE COMPLEX BETWEEN IIAMANNOSE AND IIBMANNOSE OF THE MANNOSE TRANSPORTER OF THE E. COLI PHOSPHOTRANSFERASE SYSTEM | PHOSPHOTRANSFERASE, SUGAR TRANSPORT, TRANSFERASE, COMPLEX (TRANSFERASE-PHOSPHOCARRIER, MEMBRANE, PHOSPHOPROTEIN, PHOSPHOTRANSFERASE SYSTEM
4nbs:A (VAL10) to (GLY44) THE STRUCTURE OF AIF2GAMMA SUBUNIT H20F FROM ARCHAEON SULFOLOBUS SOLFATARICUS COMPLEXED WITH GDPCP | TRANSLATION INITIATION, RNA-BINDING, GTP-BINDING, TRANSLATION
1k4i:A (ASN38) to (ASP78) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE IN COMPLEX WITH TWO MAGNESIUM IONS | DIHYDROXYBUTANONE PHOSPHATE SYNTHASE, RIBOFLAVIN BIOSYNTHESIS, ANTIMICROBIAL TARGET, STRUCTURE-BASED DESIGN, ISOMERASE
1k4l:A (ASN38) to (ASP78) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE IN COMPLEX WITH TWO MANGANESE IONS | DIHYDROXYBUTANONE PHOSPHATE SYNTHASE, RIBOFLAVIN BIOSYNTHESIS, ANTIMICROBIAL TARGET, STRUCTURE-BASED DESIGN, ISOMERASE
1k4o:A (ASN38) to (ASP78) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE IN COMPLEX WITH ONE MANGANESE, AND A GLYCEROL | DIHYDROXYBUTANONE PHOSPHATE SYNTHASE, RIBOFLAVIN BIOSYNTHESIS, ANTIMICROBIAL TARGET, STRUCTURE-BASED DESIGN, ISOMERASE
2jzh:A (LEU16) to (THR52) STRUCTURE OF IIB DOMAIN OF THE MANNOSE TRANSPORTER OF E. COLI | MANNOSE SPECIFIC PTS SYSTEM IIAB, IIB DOMAIN, IIBMAN PHOSPHOTRANSFERASE ENZYME II, B COMPONENT, CYTOPLASM, MEMBRANE, PHOSPHOPROTEIN, PHOSPHOTRANSFERASE SYSTEM, SUGAR TRANSPORT, TRANSPORT
2jzn:C (LEU216) to (THR252) SOLUTION NMR STRUCTURE OF THE PRODUCTIVE COMPLEX BETWEEN IIAMANNOSE AND IIBMANNOSE OF THE MANNOSE TRANSPORTER OF THE E. COLI PHOSPHOTRANSFERASE SYSTEM | PHOSPHOTRANSFERASE, SUGAR TRANSPORT, TRANSFERASE, COMPLEX (TRANSFERASE/PHOSPHOCARRIER, CYTOPLASM, MEMBRANE, PHOSPHOPROTEIN, PHOSPHOTRANSFERASE SYSTEM
2jzo:D (LEU166) to (THR202) SOLUTION NMR STRUCTURE OF THE NON-PRODUCTIVE COMPLEX BETWEEN IIAMANNOSE AND IIBMANNOSE OF THE MANNOSE TRANSPORTER OF THE E. COLI PHOSPHOTRANSFERASE SYSTEM | PHOSPHOTRANSFERASE, SUGAR TRANSPORT, TRANSFERASE, COMPLEX TRANSFERASE/PHOSPHOCARRIER, CYTOPLASM, MEMBRANE, PHOSPHOPROTEIN, PHOSPHOTRANSFERASE SYSTEM
3zpc:A (TYR152) to (ASP205) ACINETOBACTER BAUMANNII RIBD, FORM 1 | OXIDOREDUCTASE, REDUCTASE, DEAMINASE
1wx1:A (GLY112) to (LEU179) CRYSTAL STRUCTURE OF NICTINATE-NUCLEOTIDE-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE FROM THERMUS THERMOPHILUS HB8 | STRUCTURAL GENOMICS, THERMUS THERMOPHILUS HB8, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
1wx1:B (GLY112) to (GLY180) CRYSTAL STRUCTURE OF NICTINATE-NUCLEOTIDE-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE FROM THERMUS THERMOPHILUS HB8 | STRUCTURAL GENOMICS, THERMUS THERMOPHILUS HB8, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
1kk9:A (ALA39) to (TYR78) CRYSTAL STRUCTURE OF E. COLI YCIO | ALPHA/BETA OPEN TWISTED SHEET, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
2ydu:A (ARG255) to (ASN293) CRYSTAL STRUCTURE OF YOPH IN COMPLEX WITH 3-(1,1-DIOXIDO-3-OXOISOTHIAZOLIDIN-5-YL)BENZALDEYDE | HYDROLASE, ANTIPLAGUE DRUG DESIGN
5c7v:A (PRO115) to (GLY144) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 1H-PYRROLE-2-CARBOXYLIC ACID | FRAGMENT, COMPLEX, INHIBITOR, TRANSFERASE
5c9r:A (PRO115) to (GLY144) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 3-((4-CHLOROPHENYL)THIO)PROPANOIC ACID | COMPLEX, FRAGMENT, OXIDOREDUCTASE
5c9u:A (PRO115) to (GLY144) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 2-(2-(2,4-DICHLOROPHENYL)HYDRAZINYL)-2-OXOACETIC ACID | FRAGMENT, COMPLEX, ACETYL-TRANSFERASE, TRANSFERASE
5cak:A (PRO115) to (GLY144) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 2-HYDROXY-3-(1H-INDOL-3-YL)PROPANOIC ACID | FRAGMENT, COMPLEX, ACETYLTRANSFERASE, TRANSFERASE
5cbb:A (PRO115) to (GLY144) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 5-(3H-INDOL-3-YLIDENE)-2,5-DIHYDRO-1H-PYRAZOLE-3- CARBOXYLATE | FRAGMENT, COMPLEX, ACETYLTRANSFERASE, TRANSFERASE
1l4f:A (LYS109) to (GLY192) THE CRYSTAL STRUCTURE OF COBT COMPLEXED WITH 4,5-DIMETHYL-1,2- PHENYLENEDIAMINE AND NICOTINATE MONONUCLEOTIDE | COBT, COBALAMIN SYNTHETIC ENZYME, PHOSPHORIBOSYLTRANSFERASE, 5,6- DIMETHYLBENZIMIDAZOLE, NICOTINATE MONONUCLEOTIDE, TRANSFERASE
1l4h:A (LYS109) to (GLY192) CRYSTAL STRUCTURE OF COBT COMPLEXED WITH INDOLE AND NICOTINATE MONONUCLEOTIDE | COBT, COBALAMIN SYNTHETIC ENZYME, PHOSPHORIBOSYLTRANSFERASE, 5,6- DIMETHYLBENZIMIDAZOLE, NICOTINATE MONONUCLEOTIDE, TRANSFERASE
1l4k:A (LYS109) to (GLY192) CRYSTAL STRUCTURE OF COBT COMPLEXED WITH 3,4-DIMETHYLANILINE AND NICOTINATE MONONUCLEOTIDE | COBT, COBALAMIN SYNTHETIC ENZYME, PHOSPHORIBOSYLTRANSFERASE, 5,6- DIMETHYLBENZIMIDAZOLE, NICOTINATE MONONUCLEOTIDE, TRANSFERASE
1l4l:A (LYS109) to (GLY192) CRYSTAL STRUCTURE OF COBT COMPLEXED WITH 2,5-DIMETHYLANILINE AND NICOTINATE MONONUCLEOTIDE | COBT, COBALAMIN SYNTHETIC ENZYME, PHOSPHORIBOSYLTRANSFERASE, 5,6- DIMETHYLBENZIMIDAZOLE, NICOTINATE MONONUCLEOTIDE, TRANSFERASE
1l4m:A (LYS109) to (GLY192) CRYSTAL STRUCTURE OF COBT COMPLEXED WITH 2-AMINO-P-CRESOL AND NICOTINATE MONONUCLEOTIDE | COBT, COBALAMIN SYNTHETIC ENZYME, PHOSPHORIBOSYLTRANSFERASE, 5,6- DIMETHYLBENZIMIDAZOLE, NICOTINATE MONONUCLEOTIDE, TRANSFERASE
3jsn:A (ASN249) to (GLY294) CRYSTAL STRUCTURE OF THE ADENYLATION DOMAIN OF NAD+- DEPENDENT DNA LIGASE FROM STAPHYLOCOCCUS AUREUS | NAD+-DEPENDENT DNA LIGASE, ADENYLATION DOMAIN, STAPHYLOCOCCUS AUREUS, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, LIGASE, MAGNESIUM, MANGANESE, METAL-BINDING, NAD, ZINC
1l5k:A (LYS109) to (GLY192) CRYSTAL STRUCTURE OF COBT COMPLEXED WITH N1-(5'-PHOSPHORIBOSYL)- BENZIMIDAZOLE AND NICOTINATE | COBT, COBALAMIN SYNTHETIC ENZYME, PHOSPHORIBOSYLTRANSFERASE, 5,6- DIMETHYLBENZIMIDAZOLE, NICOTINATE MONONUCLEOTIDE, TRANSFERASE
1l5m:A (LYS109) to (GLY192) CRYSTAL STRUCTURE OF COBT COMPLEXED WITH N7-(5'-PHOSPHORIBOSYL)-2- AMINOPURINE AND NICOTINATE | COBT, COBALAMIN SYNTHETIC ENZYME, PHOSPHORIBOSYLTRANSFERASE, 5,6- DIMETHYLBENZIMIDAZOLE, NICOTINATE MONONUCLEOTIDE, TRANSFERASE
1l5o:A (LYS109) to (GLY192) CRYSTAL STRUCTURE OF COBT COMPLEXED WITH 3,4-DIMETHYLPHENOL AND NICOTINATE MONONUCLEOTIDE | COBT, COBALAMIN SYNTHETIC ENZYME, PHOSPHORIBOSYLTRANSFERASE, 5,6- DIMETHYLBENZIMIDAZOLE, NICOTINATE MONONUCLEOTIDE, TRANSFERASE
3jtw:B (VAL5) to (GLN62) CRYSTAL STRUCTURE OF PUTATIVE DIHYDROFOLATE REDUCTASE (YP_805003.1) FROM PEDIOCOCCUS PENTOSACEUS ATCC 25745 AT 1.90 A RESOLUTION | YP_805003.1, PUTATIVE DIHYDROFOLATE REDUCTASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, RIBD C-TERMINAL DOMAIN, OXIDOREDUCTASE
3jv2:A (LEU352) to (THR376) CRYSTAL STRUCTURE OF B. SUBTILIS SECA WITH BOUND PEPTIDE | PROTEIN TRANSLOCATION, ATPASE, CONFORMATIONAL CHANGE, PEPTIDE BINDING, ATP-BINDING, CELL MEMBRANE, CYTOPLASM, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PROTEIN TRANSPORT, TRANSLOCATION, TRANSPORT, ZINC
3k09:B (LYS102) to (VAL150) CRYSTAL STRUCTURE OF THE PHOSPHORYLATION-SITE MUTANT S431D OF THE KAIC CIRCADIAN CLOCK PROTEIN | KAIC, CIRCADIAN CLOCK PROTEIN, KINASE, HEXAMER, ATP-BINDING, BIOLOGICAL RHYTHMS, DNA-BINDING, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, REPRESSOR, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE
3k0c:A (LYS102) to (VAL150) CRYSTAL STRUCTURE OF THE PHOSPHORYLATION-SITE DOUBLE MUTANT S431A/T432E OF THE KAIC CIRCADIAN CLOCK PROTEIN | KAIC, CIRCADIAN CLOCK PROTEIN, KINASE, HEXAMER, ATP-BINDING, BIOLOGICAL RHYTHMS, DNA-BINDING, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, REPRESSOR, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE
5cjn:A (PRO115) to (GLY144) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 3-(3-OXO-3,4-DIHYDROQUINOXALIN-2-YL)ACRYLATE | FRAGMENT, COMPLEX, ACETYLTRANSFERASE, TRANSFERASE
3k45:A (PRO3) to (ILE60) ALTERNATE BINDING MODES OBSERVED FOR THE E- AND Z-ISOMERS OF 2,4- DIAMINOFURO[2,3D]PYRIMIDINES AS TERNARY COMPLEXES WITH NADPH AND MOUSE DIHYDROFOLATE REDUCTASE | PROTEIN LIGAND COFACTOR TERNARY COMPLEX, NADP, ONE-CARBON METABOLISM, OXIDOREDUCTASE
1ly4:A (SER6) to (ILE65) ANALYSIS OF QUINAZOLINE AND PYRIDO[2,3D]PYRIMIDINE N9-C10 REVERSED BRIDGE ANTIFOLATES IN COMPLEX WITH NADP+ AND PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE | PCDHFR, N9-C10 REVERSED BRIDGE PYRIDOPYRIMIDINE ANTIFOLATE, OXIDOREDUCTASE
1m2w:A (SER103) to (CYS137) PSEUDOMONAS FLUORESCENS MANNITOL 2-DEHYDROGENASE TERNARY COMPLEX WITH NAD AND D-MANNITOL | ROSSMANN FOLD, DI-NUCLEOTIDE BINDING MOTIF, LONG-CHAIN DEHYDROGENASE, POLYOL DEHYDROGENASE, SECONDARY ALCOHOL DEHYDROGENASE, OXIDOREDUCTASE
1m2w:B (SER103) to (CYS137) PSEUDOMONAS FLUORESCENS MANNITOL 2-DEHYDROGENASE TERNARY COMPLEX WITH NAD AND D-MANNITOL | ROSSMANN FOLD, DI-NUCLEOTIDE BINDING MOTIF, LONG-CHAIN DEHYDROGENASE, POLYOL DEHYDROGENASE, SECONDARY ALCOHOL DEHYDROGENASE, OXIDOREDUCTASE
1xxp:A (ARG255) to (ASN293) YERSINIA YOPH (RESIDUES 163-468) C403S BINDS PHOSPHOTYROSYL PEPTIDE AT TWO SITES | PEPTIDE BINDS AT SITE REMOTE FROM CATALYTIC SITE. IMPORTANT FOR PROTEIN LOCALIZATION IN INFECTED CELL., HYDROLASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
1xxp:B (ARG255) to (ASN293) YERSINIA YOPH (RESIDUES 163-468) C403S BINDS PHOSPHOTYROSYL PEPTIDE AT TWO SITES | PEPTIDE BINDS AT SITE REMOTE FROM CATALYTIC SITE. IMPORTANT FOR PROTEIN LOCALIZATION IN INFECTED CELL., HYDROLASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4p6c:A (ASN40) to (ALA80) STRUCTURE OF RIBB COMPLEXED WITH INHIBITOR 4PEH | RIBB, DHBPS, INHIBITOR, RIBOFLAVIN, COMPLEX, 4PEH, LYASE-LYASE INHIBITOR COMPLEX
4p6c:B (ASN40) to (ALA80) STRUCTURE OF RIBB COMPLEXED WITH INHIBITOR 4PEH | RIBB, DHBPS, INHIBITOR, RIBOFLAVIN, COMPLEX, 4PEH, LYASE-LYASE INHIBITOR COMPLEX
4p6d:A (ASN40) to (ARG78) STRUCTURE OF RIBB COMPLEXED WITH PO4 ION | RIBB, RIBOFLAVIN, LIGAND, COMPLEX, CRYSTAL, LYASE
4p6d:B (ASN40) to (ALA80) STRUCTURE OF RIBB COMPLEXED WITH PO4 ION | RIBB, RIBOFLAVIN, LIGAND, COMPLEX, CRYSTAL, LYASE
4p6p:A (ASN40) to (ALA80) STRUCTURE OF RIBB COMPLEXED WITH INHIBITOR (4PEH) AND METAL IONS | RIBB, RIBOFLVAIN, LIGAND, COMPLEX, CRYSTAL, LYASE-LYASE INHIBITOR COMPLEX
4p6p:B (ASN40) to (ALA80) STRUCTURE OF RIBB COMPLEXED WITH INHIBITOR (4PEH) AND METAL IONS | RIBB, RIBOFLVAIN, LIGAND, COMPLEX, CRYSTAL, LYASE-LYASE INHIBITOR COMPLEX
4p77:A (ASN40) to (ALA80) STRUCTURE OF RIBB COMPLEXED WITH SUBSTRATE RU5P | RIBB, RIBOFLVAIN, LIGAND, COMPLEX, CRYSTAL, RU5P, LYASE
4p77:B (ASN40) to (ALA80) STRUCTURE OF RIBB COMPLEXED WITH SUBSTRATE RU5P | RIBB, RIBOFLVAIN, LIGAND, COMPLEX, CRYSTAL, RU5P, LYASE
4p8e:A (ASN40) to (ALA80) STRUCTURE OF RIBB COMPLEXED WITH SUBSTRATE (RU5P) AND METAL IONS | RIBB, RIBOFLVAIN, LIGAND, COMPLEX, CRYSTAL, RU5P, ZN, LYASE
4p8e:B (ASN40) to (ALA80) STRUCTURE OF RIBB COMPLEXED WITH SUBSTRATE (RU5P) AND METAL IONS | RIBB, RIBOFLVAIN, LIGAND, COMPLEX, CRYSTAL, RU5P, ZN, LYASE
4p8j:B (ASN40) to (ALA80) STRUCTURE OF RIBB | RIBB, RIBOFLVAIN, CRYSTAL, DHBPS, RU5P
3kwv:B (VAL501) to (ASN570) STRUCTURAL BASIS FOR THE UNFOLDING OF ANTHRAX LETHAL FACTOR BY PROTECTIVE ANTIGEN OLIGOMERS | BACILLUS ANTHRACIS, PROTECTIVE ANTIGEN, LETHAL FACTOR, LETHAL TOXIN, OCTAMER, PROTEIN TRANSPORT, TOXIN, PROTEIN UNFOLDING, PROTEIN TRANSLOCATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, METAL-BINDING, SECRETED, VIRULENCE, HYDROLASE, METALLOPROTEASE, PROTEASE, TOXIN- PROTEIN TRANSPORT COMPLEX
3kwv:E (VAL501) to (ASN570) STRUCTURAL BASIS FOR THE UNFOLDING OF ANTHRAX LETHAL FACTOR BY PROTECTIVE ANTIGEN OLIGOMERS | BACILLUS ANTHRACIS, PROTECTIVE ANTIGEN, LETHAL FACTOR, LETHAL TOXIN, OCTAMER, PROTEIN TRANSPORT, TOXIN, PROTEIN UNFOLDING, PROTEIN TRANSLOCATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, METAL-BINDING, SECRETED, VIRULENCE, HYDROLASE, METALLOPROTEASE, PROTEASE, TOXIN- PROTEIN TRANSPORT COMPLEX
3adb:A (HIS-1) to (PRO44) CRYSTAL STRUCTURE OF O-PHOSPHOSERYL-TRNA KINASE COMPLEXED WITH SELENOCYSTEINE TRNA AND AMPPNP (CRYSTAL TYPE 1) | PROTEIN-RNA COMPLEX, TRNA, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, TRANSFERASE, TRANSFERASE-RNA COMPLEX
3adb:B (LEU2) to (PRO44) CRYSTAL STRUCTURE OF O-PHOSPHOSERYL-TRNA KINASE COMPLEXED WITH SELENOCYSTEINE TRNA AND AMPPNP (CRYSTAL TYPE 1) | PROTEIN-RNA COMPLEX, TRNA, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, TRANSFERASE, TRANSFERASE-RNA COMPLEX
3adc:A (HIS-1) to (PRO44) CRYSTAL STRUCTURE OF O-PHOSPHOSERYL-TRNA KINASE COMPLEXED WITH SELENOCYSTEINE TRNA AND AMPPNP (CRYSTAL TYPE 2) | PROTEIN-RNA COMPLEX, TRNA, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, TRANSFERASE, TRANSFERASE-RNA COMPLEX
3adc:B (HIS-1) to (PRO44) CRYSTAL STRUCTURE OF O-PHOSPHOSERYL-TRNA KINASE COMPLEXED WITH SELENOCYSTEINE TRNA AND AMPPNP (CRYSTAL TYPE 2) | PROTEIN-RNA COMPLEX, TRNA, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, TRANSFERASE, TRANSFERASE-RNA COMPLEX
3add:A (HIS-1) to (PRO44) CRYSTAL STRUCTURE OF O-PHOSPHOSERYL-TRNA KINASE COMPLEXED WITH SELENOCYSTEINE TRNA AND AMPPNP (CRYSTAL TYPE 3) | PROTEIN-RNA COMPLEX, TRNA, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, TRANSFERASE, TRANSFERASE-RNA COMPLEX
3add:B (HIS-1) to (PRO44) CRYSTAL STRUCTURE OF O-PHOSPHOSERYL-TRNA KINASE COMPLEXED WITH SELENOCYSTEINE TRNA AND AMPPNP (CRYSTAL TYPE 3) | PROTEIN-RNA COMPLEX, TRNA, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, TRANSFERASE, TRANSFERASE-RNA COMPLEX
5dm6:C (TRP166) to (LEU193) CRYSTAL STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS | PROTEIN SYNTHESIS, PEPTIDYLTRANSFERASE, RIBOZYME, RIBONUCLEOPROTEIN, RIBOSOME
3l7v:A (GLY33) to (LEU72) CRYSTAL STRUCTURE OF A HYPOTHETICAL PROTEIN SMU.1377C FROM STREPTOCOCCUS MUTANS UA159 | SMU.1377C, TRANSCRIPTION
1z7b:A (VAL390) to (GLY437) CRYSTAL STRUCTURE OF E.COLI ARNA DEHYDROGENASE (DECARBOXYLASE) DOMAIN, R619E MUTANT | ROSSMANN FOLD, HYDROLASE
3lfj:A (PHE6) to (ASP41) CRYSTAL STRUCTURE OF MANXB FROM THERMOANAEROBACTER TENGCONGENSIS | MANXB PTS, TRANSFERASE
3lfj:B (PHE6) to (ASP41) CRYSTAL STRUCTURE OF MANXB FROM THERMOANAEROBACTER TENGCONGENSIS | MANXB PTS, TRANSFERASE
3am1:A (ASP3) to (PRO48) CRYSTAL STRUCTURE OF O-PHOSPHOSERYL-TRNA KINASE COMPLEXED WITH ANTICODON-STEM/LOOP TRUNCATED TRNA(SEC) | KINASE, TRANSFERASE-RNA COMPLEX
5drc:A (PRO115) to (GLY144) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 2-HYDROXY-4-(1H-INDOL-3-YL)-4-OXOBUT-2-ENOIC ACID | ACETYLTRANSFERASE, TRANSFERASE
5dri:A (THR111) to (GLY144) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 2-HYDROXY-4-(1H-INDOL-5-YL)-4-OXOBUT-2-ENOIC ACID INHIBITOR | ACETYLTRANSFERASE, TRANSFERASE
1zau:A (HIS266) to (LEU310) ADENYLATION DOMAIN OF NAD+ DEPENDENT DNA LIGASE FROM M.TUBERCULOSIS | NAD+ DEPENDENT DNA LIGASE, AMP, M.TUBERCULOSIS
3lqu:A (ASN39) to (ASP79) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE COMPLEXED WITH RIBULOSE-5 PHOSPHATE | DHBPS, R5P, RIBB, LYASE, METAL BINDING, RIBOFLAVIN BIOSYNTHESIS
3lqu:B (ASN39) to (ASP79) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE COMPLEXED WITH RIBULOSE-5 PHOSPHATE | DHBPS, R5P, RIBB, LYASE, METAL BINDING, RIBOFLAVIN BIOSYNTHESIS
3lrj:A (ASN39) to (ASP79) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE IN COMPLEX WITH SULFATE ION. | ENZYME-SULFATE COMPLEX, ALPHA+BETA BARREL, DRUG TARGET, ANTIBACTERIAL, LYASE, METAL-BINDING, RIBOFLAVIN BIOSYNTHESIS
3lrj:B (ASN39) to (ASP79) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE IN COMPLEX WITH SULFATE ION. | ENZYME-SULFATE COMPLEX, ALPHA+BETA BARREL, DRUG TARGET, ANTIBACTERIAL, LYASE, METAL-BINDING, RIBOFLAVIN BIOSYNTHESIS
3lrj:C (GLU40) to (ASP79) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE IN COMPLEX WITH SULFATE ION. | ENZYME-SULFATE COMPLEX, ALPHA+BETA BARREL, DRUG TARGET, ANTIBACTERIAL, LYASE, METAL-BINDING, RIBOFLAVIN BIOSYNTHESIS
3lrj:D (ASN39) to (LEU78) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE IN COMPLEX WITH SULFATE ION. | ENZYME-SULFATE COMPLEX, ALPHA+BETA BARREL, DRUG TARGET, ANTIBACTERIAL, LYASE, METAL-BINDING, RIBOFLAVIN BIOSYNTHESIS
3ls6:A (ASN39) to (ASP79) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE IN COMPLEX WITH SULFATE AND ZINC | DHBPS, DIMETAL CENTER, DRUG TARGET, ANTIBACTERIAL, LYASE, MAGNESIUM, METAL-BINDING, RIBOFLAVIN BIOSYNTHESIS
3ls6:B (ASN39) to (ASP79) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE IN COMPLEX WITH SULFATE AND ZINC | DHBPS, DIMETAL CENTER, DRUG TARGET, ANTIBACTERIAL, LYASE, MAGNESIUM, METAL-BINDING, RIBOFLAVIN BIOSYNTHESIS
4qfm:A (VAL10) to (GLY44) THE STRUCTURE OF AIF2GAMMA SUBUNIT D152A FROM ARCHAEON SULFOLOBUS SOLFATARICUS COMPLEXED WITH GDPCP | GAMMA SUBUNIT, G-PROTEIN, TRANSLATION, TRANSLATION INITIATION,PROTEIN BIOSYNTHESIS, RNA-BINDING, GTP-BINDING,NUCLEOTIDE-BINDING
5ecv:A (PRO115) to (GLY144) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 2-HYDROXY-4-(4-METHYL-1H-INDOL-5-YL)-4-OXOBUT-2-ENOIC ACID | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4qhy:A (VAL10) to (GLY44) THE STRUCTURE OF AIF2GAMMA SUBUNIT H20F/D152A FROM ARCHAEON SULFOLOBUS SOLFATARICUS COMPLEXED WITH GDPCP | GAMMA SUBUNIT, G-PROTEIN, TRANSLATION, TRANSLATION INITIATION,PROTEIN BIOSYNTHESIS, RNA-BINDING, GTP-BINDING,NUCLEOTIDE-BINDING
4qjc:A (LEU4) to (ILE60) HUMAN DIHYDROFOLATE REDUCTASE TERNARY COMPLEX WITH NADPH AND INHIBITOR 26 (N~6~-METHYL-N~6~-(3,4,5-TRIFLUOROPHENYL)PYRIDO[2,3-D]PYRIMIDINE- 2,4,6-TRIAMINE) | DIHYDROFOLATE REDUCTASE, INHIBITOR BINDING, ROSSMAN FOLD, HYDROLASE, COFACTOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3mgz:A (GLU31) to (GLY70) CRYSTAL STRUCTURE OF DHBPS DOMAIN OF BI-FUNCTIONAL DHBPS/GTP CYCLOHYDROLASE II FROM MYCOBACTERIUM TUBERCULOSIS AT PH 4.0 | DHBPS, RIBA2, ANTIBACTERIAL, DRUG TARGET, RIBULOSE-5-PHOSPHATE, RIBOFLAVIN, LYASE
3bac:A (ARG259) to (GLY302) STRUCTURAL BASIS FOR THE INHIBITION OF BACTERIAL NAD+ DEPENDENT DNA LIGASE | ADENYLATION DOMAIN, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, LIGASE, NAD
3mio:A (ASN30) to (GLY70) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS AT PH 6.00 | DHBPS, RIBOFLAVIN, PHOSPHATE, RIBULOSE-5-PHOSPHATE, FAD, FMN, LYASE
3mio:B (GLU29) to (LEU69) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS AT PH 6.00 | DHBPS, RIBOFLAVIN, PHOSPHATE, RIBULOSE-5-PHOSPHATE, FAD, FMN, LYASE
3mk5:A (GLU31) to (GLY70) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS WITH SULFATE AND ZINC AT PH 4.00 | RIBOFLAVIN, FMN, FAD, DHBPS, SULFATE, LYASE
3bjq:B (LYS141) to (TYR191) CRYSTAL STRUCTURE OF A PHAGE-RELATED PROTEIN (BB3626) FROM BORDETELLA BRONCHISEPTICA RB50 AT 2.05 A RESOLUTION | PHAGE-RELATED PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, VIRAL PROTEIN
3bjq:E (LYS141) to (CYS189) CRYSTAL STRUCTURE OF A PHAGE-RELATED PROTEIN (BB3626) FROM BORDETELLA BRONCHISEPTICA RB50 AT 2.05 A RESOLUTION | PHAGE-RELATED PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, VIRAL PROTEIN
3bjq:I (LYS141) to (LYS190) CRYSTAL STRUCTURE OF A PHAGE-RELATED PROTEIN (BB3626) FROM BORDETELLA BRONCHISEPTICA RB50 AT 2.05 A RESOLUTION | PHAGE-RELATED PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, VIRAL PROTEIN
5ey8:H (HIS246) to (ALA291) STRUCTURE OF FADD32 FROM MYCOBACTERIUM SMEGMATIS COMPLEXED TO AMPC20 | LIGASE, FATTY-ACYL AMP LIGASE
3bqw:A (ILE170) to (SER219) CRYSTAL STRUCTURE OF THE PUTATIVE CAPSID PROTEIN OF PROPHAGE (E.COLI CFT073) | CAPSID PROTEIN, PROPHAGE, STRUCTURAL GENOMICS, MCSG, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, UNKNOWN FUNCTION
3ce9:B (LEU12) to (PHE48) CRYSTAL STRUCTURE OF GLYCEROL DEHYDROGENASE (NP_348253.1) FROM CLOSTRIDIUM ACETOBUTYLICUM AT 2.37 A RESOLUTION | NP_348253.1, GLYCEROL DEHYDROGENASE, 3-DEHYDROQUINATE SYNTHASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, OXIDOREDUCTASE
3ce9:C (LEU12) to (PHE48) CRYSTAL STRUCTURE OF GLYCEROL DEHYDROGENASE (NP_348253.1) FROM CLOSTRIDIUM ACETOBUTYLICUM AT 2.37 A RESOLUTION | NP_348253.1, GLYCEROL DEHYDROGENASE, 3-DEHYDROQUINATE SYNTHASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, OXIDOREDUCTASE
4rcy:A (VAL10) to (GLY44) STRUCTURE OF AIF2-GAMMA D19A VARIANT FROM SULFOLOBUS SOLFATARICUS BOUND TO GTP | ROSSMANN FOLD, TRANSLATION
4rd0:A (VAL10) to (GLY44) STRUCTURE OF AIF2-GAMMA D19A VARIANT FROM SULFOLOBUS SOLFATARICUS BOUND TO GDP | ROSSMANN FOLD, TRANSLATION
4rd1:A (VAL10) to (GLY44) STRUCTURE OF AIF2-GAMMA H97A VARIANT FROM SULFOLOBUS SOLFATARICUS BOUND TO GTP | ROSSMANN-FOLD, TRANSLATION
4rd2:A (VAL10) to (GLY44) STRUCTURE OF AIF2-GAMMA H97A VARIANT FROM SULFOLOBUS SOLFATARICUS BOUND TO GDPNP | ROSSMANN-FOLD, TRANSLATION
4rd3:A (VAL10) to (GLY44) STRUCTURE OF AIF2-GAMMA H97A VARIANT FROM SULFOLOBUS SOLFATARICUS BOUND TO GDP AND PI | ROSSMANN FOLD, TRANSLATION
4rjl:A (VAL10) to (GLY44) GAMMA SUBUNIT OF THE TRANSLATION INITIATION FACTOR 2 FROM SULFOLOBUS SOLFATARICUS COMPLEXED WITH GDPCP | GAMMA SUBUNIT, G-PROTEIN, TRANSLATION, TRANSLATION INITIATION,PROTEIN BIOSYNTHESIS, RNA-BINDING, GTP-BINDING, NUCLEOTIDE-BINDING
3nog:B (MET825) to (GLN872) DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) BINDERS TO ACRB: PLASTICITY OF THE INTERFACE | MEMBRANE PROTEIN, RND, DRUG-EFFLUX PUMP, TRANSPORT PROTEIN, DESIGNED ANKYRIN REPEAT PROTEIN, CRYSTALLIZATION CHAPERONE, TRANSPORT PROTEIN-PROTEIN BINDING COMPLEX
4ccj:D (ARG271) to (SER305) 60S RIBOSOMAL PROTEIN L8 HISTIDINE HYDROXYLASE (NO66) IN APO FORM | OXIDOREDUCTASE, NON-HEME, IRON-BINDING, DSBH, DIOXYGENASE, JMJC DOMAIN, RIBOSOME BIOGENESIS, NUCLEAR PROTEIN, RPL8, BETA-HYDROXYLATION, TRANSCRIPTION AND EPIGENETIC REGULATION, SIGNALING
4cck:C (ARG271) to (SER305) 60S RIBOSOMAL PROTEIN L8 HISTIDINE HYDROXYLASE (NO66) IN COMPLEX WITH MN(II) AND N-OXALYLGLYCINE (NOG) | OXIDOREDUCTASE, NON-HEME, IRON-BINDING, DSBH, 2-OXOGLUTARATE, DIOXYGENASE, JMJC DOMAIN, RIBOSOME BIOGENESIS, NUCLEAR PROTEIN, RPL8, BETA-HYDROXYLATION, TRANSCRIPTION AND EPIGENETIC REGULATION, SIGNALING
4cco:A (ARG271) to (SER305) 60S RIBOSOMAL PROTEIN L8 HISTIDINE HYDROXYLASE (NO66 S373C) IN COMPLEX WITH MN(II), N-OXALYLGLYCINE (NOG) AND 60S RIBOSOMAL PROTEIN L8 (RPL8 G214C) PEPTIDE FRAGMENT (COMPLEX-3) | OXIDOREDUCTASE, NON-HEME, IRON-BINDING, DSBH, 2-OXOGLUTARATE, DIOXYGENASE, JMJC DOMAIN, RIBOSOME BIOGENESIS, NUCLEAR PROTEIN, RPL8, BETA-HYDROXYLATION, TRANSCRIPTION AND EPIGENETIC REGULATION, SIGNALING
4cco:B (ARG271) to (SER305) 60S RIBOSOMAL PROTEIN L8 HISTIDINE HYDROXYLASE (NO66 S373C) IN COMPLEX WITH MN(II), N-OXALYLGLYCINE (NOG) AND 60S RIBOSOMAL PROTEIN L8 (RPL8 G214C) PEPTIDE FRAGMENT (COMPLEX-3) | OXIDOREDUCTASE, NON-HEME, IRON-BINDING, DSBH, 2-OXOGLUTARATE, DIOXYGENASE, JMJC DOMAIN, RIBOSOME BIOGENESIS, NUCLEAR PROTEIN, RPL8, BETA-HYDROXYLATION, TRANSCRIPTION AND EPIGENETIC REGULATION, SIGNALING
3nu0:A (LEU4) to (ILE60) DESIGN, SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTAL STRUCTURE OF NOVEL CLASSICAL 6,5,6-TRICYCLICBENZO[4,5]THIENO[2,3-D]PYRIMIDINES AS DUAL THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE INHIBITORS | DIHYDROFOLATE REDUCTASE, CYCLIZED INHIBITORS, OXIDOREDUCTASE HDHFR- 264-NADPH, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4rpj:C (ARG216) to (ASP252) CRYSTAL STRUCTURE OF MICOBACTERIUM TUBERCULOSIS UDP-GALACTOPYRANOSE MUTASE IN COMPLEX WITH UDP | UDP-GALACTOPYRANOSE MUTASE, MTUGM, FLAVOENZYME, FAD, ISOMERASE
3cse:A (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 2,4- DIAMINO-5-(3-(2,5-DIMETHOXYPHENYL)PROP-1-YNYL)-6-ETHYLPYRIMIDINE (UCP120B) | PROTEIN-LIGAND COMPLEX, REDUCTASE, OXIDOREDUCTASE
3cse:B (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 2,4- DIAMINO-5-(3-(2,5-DIMETHOXYPHENYL)PROP-1-YNYL)-6-ETHYLPYRIMIDINE (UCP120B) | PROTEIN-LIGAND COMPLEX, REDUCTASE, OXIDOREDUCTASE
3nxo:A (LEU4) to (ILE60) PERFERENTIAL SELECTION OF ISOMER BINDING FROM CHIRAL MIXTURES: ALTERNATE BINDING MODES OBSERVED FOR THE E- AND Z-ISOMERS OF A SERIES OF 5-SUBSTITUTED 2,4-DIAMINOFURO[2,3-D]PYRIMIDINES AS TERNARY COMPLEXES WITH NADPH AND HUMAN DIHYDROFOLATE REDUCTASE | E-Z-ISOMERS BINDING PREFERENCES, OXIDOREDUCTASE
3nzd:A (LEU4) to (ILE60) STRUCTURAL ANALYSIS OF PNEUMOCYSTIS CARINII AND HUMAN DHFR COMPLEXES WITH NADPH AND A SERIES OF FIVE 5-(OMEGA-CARBOXY(ALKYLOXY(PYRIDO[2,3- D]PYRIMIDINE DERIVATIVES | HUMAN DHFR INHIBITOR COMPLEXES, OXIDOREDUCTASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3nza:X (SER6) to (ILE65) STRUCTURAL ANALYSIS OF PNEUMOCYSTIS CARINII AND HUMAN DHFR COMPLEXES WITH NADPH AND A SERIES OF FIVE POTENT 5-(OMEGA-CARBOXY(ALKYLOXY) PYRIDO[2,3-D]PYRIMIDINE DERIVATIVES | PNEUMOCYSTSIS CARINII DIHYDROFOLARE REDUCTASE INHIBITOR COMPLEXES, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3nzb:X (SER6) to (ILE65) STRUCTURAL ANALYSIS OF PNEUMOCYSTIS CARINII AND HUMAN DHFR COMPLEXES WITH NADPH AND A SERIES OF POTENT 5-(OMEGA-CARBOXYL(ALKYLOXY) PYRIDO[2,-D]PYRIMIDINE DERIVATIVES | PNEUMOCYSTIUS CARINII DHFR INHIBITOR COMPLEXES, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3cwq:A (GLN69) to (LEU110) CRYSTAL STRUCTURE OF CHROMOSOME PARTITIONING PROTEIN (PARA) IN COMPLEX WITH ADP FROM SYNECHOCYSTIS SP. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SGR89 | ALPHA-BETA PROTEIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
3d80:A (LEU4) to (ILE60) STRUCTURAL ANALYSIS OF A HOLO ENZYME COMPLEX OF MOUSE DIHYDROFOLATE REDUCTASE WITH NADPH AND A TERNARY COMPLEX WTIH THE POTENT AND SELECTIVE INHIBITOR 2,4-DIAMINO-6-(2'-HYDROXYDIBENZ[B,F]AZEPIN-5-YL) METHYLPTERIDINE | MOUSE HOLO ENZYME TERNARY LIGAND COMPLEX DIHYDROFOLATE REDUCTASE, NADP, ONE-CARBON METABOLISM, OXIDOREDUCTASE
3dl6:E (VAL10) to (GLY63) CRYSTAL STRUCTURE OF THE A287F/S290G ACTIVE SITE MUTANT OF TS-DHFR FROM CRYPTOSPORIDIUM HOMINIS | ENZYME ACTIVE SITE MUTANT, ENZYME-LIGAND COMPLEX, OXIDOREDUCTASE
5hcn:A (GLN101) to (PRO147) GPN-LOOP GTPASE NPA3 IN COMPLEX WITH GMPPCP | GPN-LOOP GTPASE, CHAPERONE, ASSEMBLY, RNA POLYMERASE, HYDROLASE
5hgz:A (SER100) to (ASN143) CRYSTAL STRUCTURE OF HUMAN NAA60 IN COMPLEX WITH ACETYL-COA | N-TERMINAL ACETYLATION, COMPLEX, NATS, PROTEIN MODIFICAITON, TRANSFERASE
4diq:A (ARG271) to (SER305) CRYSTAL STRUCTURE OF HUMAN NO66 | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, HISTONE DEMETHYLASE, OXIDOREDUCTASE
3p3v:B (ILE7) to (ASP42) CRYSTAL STRUCTURE OF A PTS DEPENDENT N-ACETYL-GALACTOSAMINE-IIB COMPONENT (AGAV, SPY_0631) FROM STREPTOCOCCUS PYOGENES AT 1.65 A RESOLUTION | PTS IIB COMPONENT, PHOSPHOTRANSFERASE, SUGAR TRANSPORT, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, TRANSFERASE
4ucs:A (ARG259) to (GLY302) FRAGMENT BOUND TO H.INFLUENZA NAD DEPENDENT DNA LIGASE | LIGASE
4ucu:A (ARG259) to (GLY302) FRAGMENT BOUND TO H.INFLUENZA NAD DEPENDENT DNA LIGASE | LIGASE
3pe5:B (ARG190) to (GLU223) THREE-DIMENSIONAL STRUCTURE OF PROTEIN A7VV38_9CLOT FROM CLOSTRIDIUM LEPTUM DSM 753, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET QLR103 | STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
4e4h:D (ARG271) to (SER305) CRYSTAL STRUCTURE OF HISTONE DEMETHYLASE NO66 | JMJC DOMAIN, WHTH DOMAIN, HISTONE DEMETHYLASE, OXIDOREDUCTASE
3q8a:A (VAL501) to (ASN570) CRYSTAL STRUCTURE OF WT PROTECTIVE ANTIGEN (PH 5.5) | PROTECTIVE ANTIGEN, ANTHRAX, PH STABILITY, PROTEIN BINDING, TOXIN
3q8f:A (VAL501) to (ASN570) CRYSTAL STRUCTURE OF 2-FLUOROHISTINE LABELED PROTECTIVE ANTIGEN (PH 5.8) | PROTECTIVE ANTIGEN; 2-FLUOROHISTIDINE; ANTHRAX; PH STABILITY, PROTEIN BINDING
5j33:H (ILE114) to (LEU154) ISOPROPYLMALATE DEHYDROGENASE IN COMPLEX WITH NAD+ | DEHYDROGENASE, LEUCINE BIOSYNTHESIS, GLUCOSINOLATE BIOSYNTHESIS, OXIDOREDUCTASE
4f67:A (THR111) to (GLY141) THREE DIMENSIONAL STRUCTURE OF THE DOUBLE MUTANT OF UPF0176 PROTEIN LPG2838 FROM LEGIONELLA PNEUMOPHILA AT THE RESOLUTION 1.8A, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET LGR82 | STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UPF0176 PROTEIN LPQ2838, UNKNOWN FUNCTION
3qjg:C (ASP54) to (GLY93) EPIDERMIN BIOSYNTHESIS PROTEIN EPID FROM STAPHYLOCOCCUS AUREUS | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, OXIDOREDUCTASE
3qjg:E (ASP54) to (GLY93) EPIDERMIN BIOSYNTHESIS PROTEIN EPID FROM STAPHYLOCOCCUS AUREUS | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, OXIDOREDUCTASE
3qjg:G (ASP54) to (GLY93) EPIDERMIN BIOSYNTHESIS PROTEIN EPID FROM STAPHYLOCOCCUS AUREUS | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, OXIDOREDUCTASE
3qjg:I (ASP54) to (GLY93) EPIDERMIN BIOSYNTHESIS PROTEIN EPID FROM STAPHYLOCOCCUS AUREUS | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, OXIDOREDUCTASE
3qjg:J (ASP54) to (GLY93) EPIDERMIN BIOSYNTHESIS PROTEIN EPID FROM STAPHYLOCOCCUS AUREUS | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, OXIDOREDUCTASE
3qlz:A (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 5- [3-(2,5-DIMETHOXYPHENYL)PROP-1-YN-1-YL]-6-PROPYLPYRIMIDINE-2,4- DIAMINE (UCP130B) | ANTIFUNGAL AGENTS, CANDIDA GLABRATA, DRUG DESIGN, ENZYME INHIBITORS, FUNGAL PROTEINS, MODELS, MOLECULAR STRUCTURE, STRUCTURE-ACTIVITY RELATIONSHIP, TETRAHYDROFOLATE DEHYDROGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3qlz:B (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 5- [3-(2,5-DIMETHOXYPHENYL)PROP-1-YN-1-YL]-6-PROPYLPYRIMIDINE-2,4- DIAMINE (UCP130B) | ANTIFUNGAL AGENTS, CANDIDA GLABRATA, DRUG DESIGN, ENZYME INHIBITORS, FUNGAL PROTEINS, MODELS, MOLECULAR STRUCTURE, STRUCTURE-ACTIVITY RELATIONSHIP, TETRAHYDROFOLATE DEHYDROGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
4ffj:A (GLU30) to (MET69) THE CRYSTAL STRUCTURE OF SPDHBPS FROM S.PNEUMONIAE | BARREL STRUCTURE, LYASE
5jsz:F (GLY68) to (LEU98) FOLATE ECF TRANSPORTER: APO STATE | ECF TRANSPORTER, FOLATE, MEMBRANE PROTEIN, VITAMIN TRANSPORT, TRANSPORT PROTEIN
4gh8:B (MET1) to (ILE51) CRYSTAL STRUCTURE OF A 'HUMANIZED' E. COLI DIHYDROFOLATE REDUCTASE | TETRAHYDROFOLATE, ENZYME CATALYSIS, EVOLUTION, DIHYDROFOLATE REDUCTASE, OXIDOREDUCTASE
5t8g:A (PRO115) to (GLY144) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 2-OXO-4-((THIOPHENE-2-CARBONYL)OXY)BUTANOIC ACID | TRANSFERASE, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3f8y:A (LEU4) to (ILE60) CORRELATIONS OF HUMAN DIHYDROFOLATE REDUCTASE WITH STRUCTURAL DATA FOR HUMAN ACTIVE SITE MUTANT ENZYME COMPLEXES | ACTIVE SITE MUTANTS LIGAND COMPLEX DHFR, NADP, ONE-CARBON METABOLISM, OXIDOREDUCTASE
4xt7:A (GLY38) to (GLY92) CRYSTAL STRUCTURE OF RV2671 FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH NADP+ AND TRIMETHOPRIM | TRIMETHOPRIM, REDUCTASE, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, OXIDOREDUCTASE
2qpu:B (ASP118) to (SER186) SUGAR TONGS MUTANT S378P IN COMPLEX WITH ACARBOSE | ALPHA BETA 8 BARREL, SUGAR TONGS MUTANT COMPLEX, CARBOHYDRATE METABOLISM, GERMINATION, GLYCOSIDASE, HYDROLASE, METAL-BINDING, SECRETED
1dr6:A (LEU4) to (ILE60) CRYSTAL STRUCTURES OF ORGANOMERCURIAL-ACTIVATED CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXES | OXIDOREDUCTASE
4ixe:D (SER6) to (ILE65) PCDHFR-NADPH-270 | DIHYDROFOLATE REDUCTASE INHIBITOR COFACTOR TERNARY COMPLEX, REDUCTASE, OXIDOREDUCTASE-INHIBITOR COMPLEX
3gn6:A (GLN37) to (GLY109) CRYSTAL STRUCTURE OF CT0912, ORFAN PROTEIN FROM CHLOROBIUM TEPIDUM WITH A FERREDOXIN-LIKE DOMAIN REPEAT (NP_661805.1) FROM CHLOROBIUM TEPIDUM TLS AT 1.80 A RESOLUTION | NP_661805.1, CT0912, ORFAN PROTEIN FROM CHLOROBIUM TEPIDUM WITH A FERREDOXIN-LIKE DOMAIN REPEAT, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
3gn6:C (GLN37) to (GLY109) CRYSTAL STRUCTURE OF CT0912, ORFAN PROTEIN FROM CHLOROBIUM TEPIDUM WITH A FERREDOXIN-LIKE DOMAIN REPEAT (NP_661805.1) FROM CHLOROBIUM TEPIDUM TLS AT 1.80 A RESOLUTION | NP_661805.1, CT0912, ORFAN PROTEIN FROM CHLOROBIUM TEPIDUM WITH A FERREDOXIN-LIKE DOMAIN REPEAT, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
3gn6:D (GLN37) to (ALA108) CRYSTAL STRUCTURE OF CT0912, ORFAN PROTEIN FROM CHLOROBIUM TEPIDUM WITH A FERREDOXIN-LIKE DOMAIN REPEAT (NP_661805.1) FROM CHLOROBIUM TEPIDUM TLS AT 1.80 A RESOLUTION | NP_661805.1, CT0912, ORFAN PROTEIN FROM CHLOROBIUM TEPIDUM WITH A FERREDOXIN-LIKE DOMAIN REPEAT, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
3h07:A (GLU38) to (ASP79) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE FROM YERSINIA PESTIS CO92 | RIBB,3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE, BIOSYNTHESIS OF COENZYME, CSGID, LYASE, MAGNESIUM, MANGANESE, METAL-BINDING, RIBOFLAVIN BIOSYNTHESIS, STRUCTURAL GENOMICS, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES
3h07:B (ASN39) to (ASP79) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE FROM YERSINIA PESTIS CO92 | RIBB,3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE, BIOSYNTHESIS OF COENZYME, CSGID, LYASE, MAGNESIUM, MANGANESE, METAL-BINDING, RIBOFLAVIN BIOSYNTHESIS, STRUCTURAL GENOMICS, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES
4kqj:A (VAL126) to (GLY192) CRYSTAL STRUCTURE OF COBT S80Y/Q88M/L175M COMPLEXED WITH P-CRESOL AND NAMN | TRANSFERASE
3veo:A (ARG423) to (LEU464) CRYSTAL STRUCTURE OF THE O-CARBAMOYLTRANSFERASE TOBZ IN COMPLEX WITH CARBAMOYL PHOSPHATE | ANTIBIOTIC BIOSYNTHESIS, SUBSTRATE ASSISTED CATALYSIS, SUBSTRATE CHANNELING, ADENYLATION, STRUCTURAL ENZYMOLOGY, ENZYME EVOLUTION, TRANSFERASE
2h2q:B (PHE23) to (ILE84) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI DIHYDROFOLATE REDUCTASE- THYMIDYLATE SYNTHASE | BIFUNCTIONAL ENZYME IN COMPLEX WITH NADP AND DUMP, OXIDOREDUCTASE, TRANSFERASE
1tks:A (GLU30) to (GLU71) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE OF CANDIDA ALBICANS | CANDIDA ALBICANS, RIBOFLAVIN BIOSYNTHESIS, 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE, CRYSTAL STRUCTURE SYNTHETIC GENE, ISOMERASE
1tks:B (GLU30) to (GLU71) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE OF CANDIDA ALBICANS | CANDIDA ALBICANS, RIBOFLAVIN BIOSYNTHESIS, 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE, CRYSTAL STRUCTURE SYNTHETIC GENE, ISOMERASE
3vth:B (GLY225) to (LYS264) CRYSTAL STRUCTURE OF FULL-LENGTH HYPF IN THE PHOSPHATE- AND NUCLEOTIDE-BOUND FORM | CARBAMOYLTRANSFER, MATURATION OF [NIFE]-HYDROGENASE, CARBAMOYLPHOSPHATE, IRON, HYPE, TRANSFERASE
3j1c:H (LYS377) to (VAL436) CRYO-EM STRUCTURE OF 9-FOLD SYMMETRIC RATCPN-ALPHA IN APO STATE | GROUP II CHAPERONIN, CHAPERONE
4mdy:A (ALA235) to (ASP268) CRYSTAL STRUCTURE OF PERIPLASMIC SOLUTE BINDING PROTEIN FROM MYCOBACTERIUM SMEGMATIS STR. MC2 155 | MCSG, STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, ABC TRANSPORTER SYSTEM, SOLUTE BINDING PROTEIN, TRANSPORT PROTEIN
1k49:A (ASN38) to (ASP78) CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE (CATION FREE FORM) | DIHYDROXYBUTANONE PHOSPHATE SYNTHASE, RIBOFLAVIN BIOSYNTHESIS, ANTIMICROBIAL TARGET, STRUCTURE-BASED DESIGN, ISOMERASE
5c9x:A (GLY114) to (GLY144) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 2,4-DICHLORO-5-FLUOROBENZOIC ACID | FRAGMENT, COMPLEX, TRANSFERASE
1l4g:A (LYS109) to (GLY192) CRYSTAL STRUCTURE OF COBT COMPLEXED WITH 4-METHYLCATECHOL AND NICOTINATE MONONUCLEOTIDE | COBT, COBALAMIN SYNTHETIC ENZYME, PHOSPHORIBOSYLTRANSFERASE, 5,6- DIMETHYLBENZIMIDAZOLE, NICOTINATE MONONUCLEOTIDE, TRANSFERASE
3jzd:A (ALA13) to (GLN47) CRYSTAL STRUCTURE OF PUTATIVE ALCOHOL DEHEDROGENASE (YP_298327.1) FROM RALSTONIA EUTROPHA JMP134 AT 2.10 A RESOLUTION | YP_298327.1, PUTATIVE ALCOHOL DEHEDROGENASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, OXIDOREDUCTASE
1lj8:A (ASP104) to (CYS137) CRYSTAL STRUCTURE OF MANNITOL DEHYDROGENASE IN COMPLEX WITH NAD | OXIDOREDUCTASE, NAD, LONG-CHAIN DEHYDROGENASE
2o3i:B (LEU164) to (LEU220) X-RAY CRYSTAL STRUCTURE OF PROTEIN CV_3147 FROM CHROMOBACTERIUM VIOLACEUM. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET CVR68. | NESG, CVR68, Q7NTB2, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, UNKNOWN FUNCTION
5d2i:A (ALA118) to (ASN162) 4-OXALOCROTONATE DECARBOXYLASE FROM PSEUDOMONAS PUTIDA G7 - COMPLEXED WITH CALCIUM AND ACETATE | NAPHTHALENE DEGRADATION, LYASE
5d2i:B (ALA118) to (ASN162) 4-OXALOCROTONATE DECARBOXYLASE FROM PSEUDOMONAS PUTIDA G7 - COMPLEXED WITH CALCIUM AND ACETATE | NAPHTHALENE DEGRADATION, LYASE
1ypt:A (ARG255) to (ASN293) CRYSTAL STRUCTURE OF YERSINIA PROTEIN TYROSINE PHOSPHATASE AT 2.5 ANGSTROMS AND THE COMPLEX WITH TUNGSTATE | HYDROLASE, PROTEIN TYROSINE PHOSPHATASE
1ypt:B (ARG255) to (ASN293) CRYSTAL STRUCTURE OF YERSINIA PROTEIN TYROSINE PHOSPHATASE AT 2.5 ANGSTROMS AND THE COMPLEX WITH TUNGSTATE | HYDROLASE, PROTEIN TYROSINE PHOSPHATASE
4rcz:A (VAL10) to (GLY44) STRUCTURE OF AIF2-GAMMA D19A VARIANT FROM SULFOLOBUS SOLFATARICUS BOUND TO GDPNP | ROSSMANN FOLD, TRANSLATION
4rd4:A (VAL10) to (GLY44) STRUCTURE OF AIF2 GAMMA FROM SULFOLOBUS SOLFATARICUS BOUND TO GDPNP | ROSSMANN FOLD, TRANSLATION
4rpl:A (ARG216) to (ASP252) CRYSTAL STRUCTURE OF MICOBACTERIUM TUBERCULOSIS UDP-GALACTOPYRANOSE MUTASE IN COMPLEX WITH TETRAFLUORINATED SUBSTRATE ANALOG UDP-F4-GALP | UDP-GALACTOPYRANOSE MUTASE, MTUGM, FLAVOENZYME, FAD, ISOMERASE
3d84:X (PRO3) to (ILE60) STRUCTURAL ANALYSIS OF A HOLO ENZYME COMPLEX OF MOUSE DIHYDROFOLATE REDUCTASE WITH NADPH AND A TERNARY COMPLEX WITH THE POTENT AND SELECTIVE INHIBITOR 2.4-DIAMINO-6-(-2'-HYDROXYDIBENZ[B,F]AZEPIN-5- YL)METHYLPTERIDINE | MOUSE DHFR HOLO ENZYME AND TERNARY LIGAND COMPLEX, NADP, ONE-CARBON METABOLISM, OXIDOREDUCTASE
4ucr:A (ARG259) to (GLY302) FRAGMENT BOUND TO H.INFLUENZA NAD DEPENDENT DNA LIGASE | LIGASE
4ufz:A (ARG259) to (GLY302) SYNTHESIS OF NOVEL NAD DEPENDANT DNA LIGASE INHIBITORS VIA NEGISHI CROSS-COUPLING: DEVELOPMENT OF SAR AND RESISTANCE STUDIES | LIGASE
3pn1:A (ARG259) to (GLY302) NOVEL BACTERIAL NAD+-DEPENDENT DNA LIGASE INHIBITORS WITH BROAD SPECTRUM POTENCY AND ANTIBACTERIAL EFFICACY IN VIVO | ATP GRASP FOLD, LIGASE, DNA, BACTERIA, LIGASE-LIGASE INHIBITOR COMPLEX
3qlx:A (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 6- METHYL-5-[(3R)-3-(3,4,5-TRIMETHOXYPHENYL)PENT-1-YN-1-YL]PYRIMIDINE-2, 4-DIAMINE (UCP112A) | ANTIFUNGAL AGENTS, CANDIDA GLABRATA, DRUG DESIGN, ENZYME INHIBITORS, FUNGAL PROTEINS, MODELS, MOLECULAR STRUCTURE, STRUCTURE-ACTIVITY RELATIONSHIP, TETRAHYDROFOLATE DEHYDROGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3qlx:B (VAL6) to (ILE62) CANDIDA GLABRATA DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 6- METHYL-5-[(3R)-3-(3,4,5-TRIMETHOXYPHENYL)PENT-1-YN-1-YL]PYRIMIDINE-2, 4-DIAMINE (UCP112A) | ANTIFUNGAL AGENTS, CANDIDA GLABRATA, DRUG DESIGN, ENZYME INHIBITORS, FUNGAL PROTEINS, MODELS, MOLECULAR STRUCTURE, STRUCTURE-ACTIVITY RELATIONSHIP, TETRAHYDROFOLATE DEHYDROGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
4g9i:B (HIS225) to (ALA264) CRYSTAL STRUCTURE OF T.KODAKARENSIS HYPF | ZINC FINGER, HYDROGENASE MATURATION, ATP BINDING, CARBAMOYLATION, TRANSFERASE
4g9i:D (HIS225) to (ALA264) CRYSTAL STRUCTURE OF T.KODAKARENSIS HYPF | ZINC FINGER, HYDROGENASE MATURATION, ATP BINDING, CARBAMOYLATION, TRANSFERASE
4g9i:E (HIS225) to (ALA264) CRYSTAL STRUCTURE OF T.KODAKARENSIS HYPF | ZINC FINGER, HYDROGENASE MATURATION, ATP BINDING, CARBAMOYLATION, TRANSFERASE
4g9i:F (HIS225) to (ALA264) CRYSTAL STRUCTURE OF T.KODAKARENSIS HYPF | ZINC FINGER, HYDROGENASE MATURATION, ATP BINDING, CARBAMOYLATION, TRANSFERASE