1a2p:C (PHE7) to (GLY34) BARNASE WILDTYPE STRUCTURE AT 1.5 ANGSTROMS RESOLUTION | RIBONUCLEASE, MICROBIAL RIBONUCLEASE, ALPHA/BETA PROTEIN
4wg2:A (PRO25) to (ASP63) P411BM3-CIS T438S I263F REGIOSELECTIVE C-H AMINATION CATALYST | P411BM3-CIS, ENGINEERING, CATALYSIS, OXIDOREDUCTASE
4wg2:B (PRO25) to (ASP63) P411BM3-CIS T438S I263F REGIOSELECTIVE C-H AMINATION CATALYST | P411BM3-CIS, ENGINEERING, CATALYSIS, OXIDOREDUCTASE
4wg2:C (PRO25) to (ASP63) P411BM3-CIS T438S I263F REGIOSELECTIVE C-H AMINATION CATALYST | P411BM3-CIS, ENGINEERING, CATALYSIS, OXIDOREDUCTASE
3ebs:A (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A6 I208S/I300F/G301A/S369G IN COMPLEX WITH PHENACETIN | CYP2A6, P450 2A6, CYP2A13, P450 2A13, MONOOXYGENASE, OXIDOREDUCATASE, HEME, ENDOPLASMIC RETICULUM, IRON, MEMBRANE, METAL-BINDING, MICROSOME, PHENACETIN, OXIDOREDUCTASE, POLYMORPHISM
3ebs:B (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A6 I208S/I300F/G301A/S369G IN COMPLEX WITH PHENACETIN | CYP2A6, P450 2A6, CYP2A13, P450 2A13, MONOOXYGENASE, OXIDOREDUCATASE, HEME, ENDOPLASMIC RETICULUM, IRON, MEMBRANE, METAL-BINDING, MICROSOME, PHENACETIN, OXIDOREDUCTASE, POLYMORPHISM
3ebs:C (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A6 I208S/I300F/G301A/S369G IN COMPLEX WITH PHENACETIN | CYP2A6, P450 2A6, CYP2A13, P450 2A13, MONOOXYGENASE, OXIDOREDUCATASE, HEME, ENDOPLASMIC RETICULUM, IRON, MEMBRANE, METAL-BINDING, MICROSOME, PHENACETIN, OXIDOREDUCTASE, POLYMORPHISM
3ebs:D (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A6 I208S/I300F/G301A/S369G IN COMPLEX WITH PHENACETIN | CYP2A6, P450 2A6, CYP2A13, P450 2A13, MONOOXYGENASE, OXIDOREDUCATASE, HEME, ENDOPLASMIC RETICULUM, IRON, MEMBRANE, METAL-BINDING, MICROSOME, PHENACETIN, OXIDOREDUCTASE, POLYMORPHISM
3ruk:A (MET49) to (GLY90) HUMAN CYTOCHROME P450 CYP17A1 IN COMPLEX WITH ABIRATERONE | CYTOCHROME P450, CYP17A1, P450 17A1, MONOOXYGENASE, 17A-HYDROXYLASE, 17,20-LYASE, HEME PROTEIN, CYTOCHROME P450 OXIDOREDUCTASE, ABIRATERONE, ZYTIGA, 17A-HYDROXYLATION, MEMBRANE, MICROSOME, ENDOPLASMIC RETICULUM, GALETERONE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3ruk:B (MET49) to (GLY90) HUMAN CYTOCHROME P450 CYP17A1 IN COMPLEX WITH ABIRATERONE | CYTOCHROME P450, CYP17A1, P450 17A1, MONOOXYGENASE, 17A-HYDROXYLASE, 17,20-LYASE, HEME PROTEIN, CYTOCHROME P450 OXIDOREDUCTASE, ABIRATERONE, ZYTIGA, 17A-HYDROXYLATION, MEMBRANE, MICROSOME, ENDOPLASMIC RETICULUM, GALETERONE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4wnt:A (THR54) to (GLY95) HUMAN CYTOCHROME P450 2D6 AJMALICINE COMPLEX | CYP2D6, P450 2D6, CYTOCHROME P450, MONOOXYGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
4wnu:A (THR54) to (GLY95) HUMAN CYTOCHROME P450 2D6 QUINIDINE COMPLEX | CYP2D6, P450 2D6, CYTOCHROME P450, MONOOXYGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
4wnu:C (THR54) to (GLY95) HUMAN CYTOCHROME P450 2D6 QUINIDINE COMPLEX | CYP2D6, P450 2D6, CYTOCHROME P450, MONOOXYGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
4wnv:A (THR54) to (GLY95) HUMAN CYTOCHROME P450 2D6 QUININE COMPLEX | CYP2D6, P450 2D6, P450, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4wnw:A (THR54) to (GLY95) HUMAN CYTOCHROME P450 2D6 THIORIDAZINE COMPLEX | CYP2D6, P450 2D6, P450, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4wnw:B (THR54) to (GLY95) HUMAN CYTOCHROME P450 2D6 THIORIDAZINE COMPLEX | CYP2D6, P450 2D6, P450, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4h23:A (PRO25) to (ALA61) CYTOCHROME P411BM3-CIS CYCLOPROPANATION CATALYST | CYTOCHROME P450, ENZYMATIC CYCLOPROPANATION, DIRECTED EVOLUTION, NON- NATURAL FUNCTION, OXIDOREDUCTASE
4h23:B (PRO25) to (ASP63) CYTOCHROME P411BM3-CIS CYCLOPROPANATION CATALYST | CYTOCHROME P450, ENZYMATIC CYCLOPROPANATION, DIRECTED EVOLUTION, NON- NATURAL FUNCTION, OXIDOREDUCTASE
4h24:A (PRO25) to (ASP63) CYTOCHROME P450BM3-CIS CYCLOPROPANATION CATALYST | CYTOCHROME P450, ENZYMATIC CYCLOPROPANATION, DIRECTED EVOLUTION, NON- NATURAL FUNCTION, OXIDOREDUCTASE
4h24:B (PRO25) to (ASP63) CYTOCHROME P450BM3-CIS CYCLOPROPANATION CATALYST | CYTOCHROME P450, ENZYMATIC CYCLOPROPANATION, DIRECTED EVOLUTION, NON- NATURAL FUNCTION, OXIDOREDUCTASE
4h24:C (PRO25) to (ASP63) CYTOCHROME P450BM3-CIS CYCLOPROPANATION CATALYST | CYTOCHROME P450, ENZYMATIC CYCLOPROPANATION, DIRECTED EVOLUTION, NON- NATURAL FUNCTION, OXIDOREDUCTASE
4h24:D (PRO25) to (ASP63) CYTOCHROME P450BM3-CIS CYCLOPROPANATION CATALYST | CYTOCHROME P450, ENZYMATIC CYCLOPROPANATION, DIRECTED EVOLUTION, NON- NATURAL FUNCTION, OXIDOREDUCTASE
3ekb:A (PRO25) to (CYS62) CRYSTAL STRUCTURE OF THE A264C MUTANT HEME DOMAIN OF CYTOCHROME P450 BM3 | HEME LIGATION, P450, CYTOCHROME, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL- BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3ekb:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE A264C MUTANT HEME DOMAIN OF CYTOCHROME P450 BM3 | HEME LIGATION, P450, CYTOCHROME, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL- BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3ekd:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE A264M HEME DOMAIN OF CYTOCHROME P450 BM3 | HEME LIGATION, CYTOCHROME P450, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL- BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3ekf:A (PRO25) to (CYS62) CRYSTAL STRUCTURE OF THE A264Q HEME DOMAIN OF CYTOCHROME P450 BM3 | HEME LIGATION, CYTOCHROME P450, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL- BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3ekf:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE A264Q HEME DOMAIN OF CYTOCHROME P450 BM3 | HEME LIGATION, CYTOCHROME P450, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL- BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
4h6o:A (PHE55) to (PHE90) STEROL 14-ALPHA DEMETHYLASE (CYP51)FROM TRYPANOSOMA CRUZI IN COMPLEX WITH THE INHIBITOR NEU321 (1-(3-(4-CHLORO-3,5-DIMETHYLPHENOXY) BENZYL)-1H-IMIDAZOLE | STEROL 14-ALPHA DEMETHYLASE (CYP51), CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3el3:A (PRO44) to (ASN82) DISTINCT MONOOXYGENASE AND FARNESENE SYNTHASE ACTIVE SITES IN CYTOCHROME P450 170A1 | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP170A1, ANTIBIOTIC BIOSYNTHESIS, FARNESENE SYNTHASE, HEME, IRON, METAL-BINDING, MONOOXYGENASE
3el3:B (PRO44) to (ASN82) DISTINCT MONOOXYGENASE AND FARNESENE SYNTHASE ACTIVE SITES IN CYTOCHROME P450 170A1 | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP170A1, ANTIBIOTIC BIOSYNTHESIS, FARNESENE SYNTHASE, HEME, IRON, METAL-BINDING, MONOOXYGENASE
1b20:C (PHE7) to (GLY34) DELETION OF A BURIED SALT-BRIDGE IN BARNASE | MICROBIAL RIBONUCLEASE, ALPHA/BETA PROTEIN, HYDROLASE
1b21:C (PHE7) to (GLY34) DELETION OF A BURIED SALT BRIDGE IN BARNASE | MICROBIAL RIBONUCLEASE, ALPHA/BETA PROTEIN, HYDROLASE
3eqm:A (ILE70) to (HIS109) CRYSTAL STRUCTURE OF HUMAN PLACENTAL AROMATASE CYTOCHROME P450 IN COMPLEX WITH ANDROSTENEDIONE | HUMAN AROMATASE, CYTOCHROME P450, MEMBRANE PROTEIN, MICROSOMAL, ESTROGEN, BIOSYNTHESIS OF STEROID HORMONE, DISEASE MUTATION, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE, PHOSPHOPROTEIN
1b2s:C (PHE7) to (GLY34) STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE | RNASE-INHIBITOR COMPLEX, INTERFACIAL DOUBLE MUTANT, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1b2u:C (PHE7) to (GLY34) STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE | RNASE-INHIBITOR COMPLEX, INTERFACIAL DOUBLE MUTANT, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1b2x:C (PHE7) to (GLY34) BARNASE WILDTYPE STRUCTURE AT PH 7.5 FROM A CRYO_COOLED CRYSTAL AT 100K | MICROBIAL RIBONUCLEASE, ALPHA/BETA PROTEIN, HYDROLASE
1b2z:C (PHE7) to (GLY34) DELETION OF A BURIED SALT BRIDGE IN BARNASE | MICROBIAL RIBONUCLEASE, ALPHA/BETA PROTEIN, HYDROLASE
2p85:A (MET54) to (ALA95) STRUCTURE OF HUMAN LUNG CYTOCHROME P450 2A13 WITH INDOLE BOUND IN TWO ALTERNATE CONFORMATIONS | CYP2A13, P450 2A13, P450, MONOOXYGENASE, NICOTINE OXIDASE, COUMARINE 7-HYDROXYLASE, NNK OXIDASE, 4-(METHYLNITROSAMINO)- 1-(3-PYRIDYL)-1-BUTANONE OXIDASE, OXIDOREDUCTASE, HEME
2p85:B (MET54) to (ALA95) STRUCTURE OF HUMAN LUNG CYTOCHROME P450 2A13 WITH INDOLE BOUND IN TWO ALTERNATE CONFORMATIONS | CYP2A13, P450 2A13, P450, MONOOXYGENASE, NICOTINE OXIDASE, COUMARINE 7-HYDROXYLASE, NNK OXIDASE, 4-(METHYLNITROSAMINO)- 1-(3-PYRIDYL)-1-BUTANONE OXIDASE, OXIDOREDUCTASE, HEME
2p85:D (MET54) to (ALA95) STRUCTURE OF HUMAN LUNG CYTOCHROME P450 2A13 WITH INDOLE BOUND IN TWO ALTERNATE CONFORMATIONS | CYP2A13, P450 2A13, P450, MONOOXYGENASE, NICOTINE OXIDASE, COUMARINE 7-HYDROXYLASE, NNK OXIDASE, 4-(METHYLNITROSAMINO)- 1-(3-PYRIDYL)-1-BUTANONE OXIDASE, OXIDOREDUCTASE, HEME
2p85:E (MET54) to (ALA95) STRUCTURE OF HUMAN LUNG CYTOCHROME P450 2A13 WITH INDOLE BOUND IN TWO ALTERNATE CONFORMATIONS | CYP2A13, P450 2A13, P450, MONOOXYGENASE, NICOTINE OXIDASE, COUMARINE 7-HYDROXYLASE, NNK OXIDASE, 4-(METHYLNITROSAMINO)- 1-(3-PYRIDYL)-1-BUTANONE OXIDASE, OXIDOREDUCTASE, HEME
2p85:F (MET54) to (ALA95) STRUCTURE OF HUMAN LUNG CYTOCHROME P450 2A13 WITH INDOLE BOUND IN TWO ALTERNATE CONFORMATIONS | CYP2A13, P450 2A13, P450, MONOOXYGENASE, NICOTINE OXIDASE, COUMARINE 7-HYDROXYLASE, NNK OXIDASE, 4-(METHYLNITROSAMINO)- 1-(3-PYRIDYL)-1-BUTANONE OXIDASE, OXIDOREDUCTASE, HEME
4hgg:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF P450 BM3 5F5R HEME DOMAIN VARIANT COMPLEXED WITH STYRENE | OXIDOREDUCTASE, P450 BM3, HEMOPROTEIN, STYRENE EPOXIDATION, INVERTED ENANTIOSELECTIVITY, HEME BINDING
4hgg:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF P450 BM3 5F5R HEME DOMAIN VARIANT COMPLEXED WITH STYRENE | OXIDOREDUCTASE, P450 BM3, HEMOPROTEIN, STYRENE EPOXIDATION, INVERTED ENANTIOSELECTIVITY, HEME BINDING
2bfq:A (ALA55) to (PHE120) MACRO DOMAINS ARE ADP-RIBOSE BINDING MOLECULES | HISTONE MACROH2A, P-LOOP, NUCLEOTIDE, HYDROLASE, MACRO_H2A DOMAIN, ADP RIBOSE-BINDING PROTEIN
2bfr:A (ALA55) to (PHE120) THE MACRO DOMAIN IS AN ADP-RIBOSE BINDING MODULE | HISTONE MACROH2A, CRYSTAL STRUCTURE P-LOOP, NUCLEOTIDE, HYDROLASE, MACRO_H2A DOMAIN/HYDROLASE
4hgj:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF P450 BM3 5F5 HEME DOMAIN VARIANT | OXIDOREDUCTASE, P450 BM3, HEMOPROTEIN, STYRENE EPOXIDATION, INVERTED ENANTIOSELECTIVITY, HEME BINDING
4hgj:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF P450 BM3 5F5 HEME DOMAIN VARIANT | OXIDOREDUCTASE, P450 BM3, HEMOPROTEIN, STYRENE EPOXIDATION, INVERTED ENANTIOSELECTIVITY, HEME BINDING
1ban:B (PHE7) to (GLY34) THE CONTRIBUTION OF BURIED HYDROGEN BONDS TO PROTEIN STABILITY: THE CRYSTAL STRUCTURES OF TWO BARNASE MUTANTS | ENDONUCLEASE
1bao:A (PHE7) to (GLY34) THE CONTRIBUTION OF BURIED HYDROGEN BONDS TO PROTEIN STABILITY: THE CRYSTAL STRUCTURES OF TWO BARNASE MUTANTS | ENDONUCLEASE
1bao:B (PHE7) to (GLY34) THE CONTRIBUTION OF BURIED HYDROGEN BONDS TO PROTEIN STABILITY: THE CRYSTAL STRUCTURES OF TWO BARNASE MUTANTS | ENDONUCLEASE
1bao:C (PHE7) to (GLY34) THE CONTRIBUTION OF BURIED HYDROGEN BONDS TO PROTEIN STABILITY: THE CRYSTAL STRUCTURES OF TWO BARNASE MUTANTS | ENDONUCLEASE
2bmh:A (PRO25) to (ASP63) MODELING PROTEIN-SUBSTRATE INTERACTIONS IN THE HEME DOMAIN OF CYTOCHROME P450BM-3 | OXIDOREDUCTASE(OXYGENASE)
2bmh:B (PRO25) to (ALA61) MODELING PROTEIN-SUBSTRATE INTERACTIONS IN THE HEME DOMAIN OF CYTOCHROME P450BM-3 | OXIDOREDUCTASE(OXYGENASE)
1bne:A (THR6) to (GLY34) BARNASE A43C/S80C DISULFIDE MUTANT | ENDONUCLEASE
1bnf:A (PHE7) to (GLY34) BARNASE T70C/S92C DISULFIDE MUTANT | ENDONUCLEASE
1bnf:C (PHE7) to (GLY34) BARNASE T70C/S92C DISULFIDE MUTANT | ENDONUCLEASE
1bni:B (PHE7) to (GLY34) BARNASE WILDTYPE STRUCTURE AT PH 6.0 | ALPHA/BETA PROTEIN, MICROBIAL RIBONUCLEASE
1bni:C (PHE7) to (GLY34) BARNASE WILDTYPE STRUCTURE AT PH 6.0 | ALPHA/BETA PROTEIN, MICROBIAL RIBONUCLEASE
1bnj:B (PHE7) to (GLY34) BARNASE WILDTYPE STRUCTURE AT PH 9.0 | ALPHA/BETA PROTEIN, MICROBIAL RIBONUCLEASE
1bnj:C (PHE7) to (GLY34) BARNASE WILDTYPE STRUCTURE AT PH 9.0 | ALPHA/BETA PROTEIN, MICROBIAL RIBONUCLEASE
1bns:C (THR6) to (GLY34) STRUCTURAL STUDIES OF BARNASE MUTANTS | ENDONUCLEASE
3s79:A (ILE70) to (ASN110) HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1) REFINED AT 2.75 ANGSTROM | OXIDOREDUCTASE
1brh:A (PHE7) to (GLY34) BARNASE MUTANT WITH LEU 14 REPLACED BY ALA | ALPHA/BETA PROTEIN, ENDONUCLEASE
1brh:C (PHE7) to (GLY34) BARNASE MUTANT WITH LEU 14 REPLACED BY ALA | ALPHA/BETA PROTEIN, ENDONUCLEASE
1bri:B (PHE7) to (GLY34) BARNASE MUTANT WITH ILE 76 REPLACED BY ALA | ALPHA/BETA PROTEIN ALPHA/BETA PROTEIN, ENDONUCLEASE
1bri:C (PHE7) to (GLY34) BARNASE MUTANT WITH ILE 76 REPLACED BY ALA | ALPHA/BETA PROTEIN ALPHA/BETA PROTEIN, ENDONUCLEASE
1brj:A (PHE7) to (GLY34) BARNASE MUTANT WITH ILE 88 REPLACED BY ALA | ALPHA/BETA PROTEIN, ENDONUCLEASE
1brj:B (PHE7) to (GLY34) BARNASE MUTANT WITH ILE 88 REPLACED BY ALA | ALPHA/BETA PROTEIN, ENDONUCLEASE
1brj:C (PHE7) to (GLY34) BARNASE MUTANT WITH ILE 88 REPLACED BY ALA | ALPHA/BETA PROTEIN, ENDONUCLEASE
1brk:B (PHE7) to (GLY34) BARNASE MUTANT WITH ILE 96 REPLACED BY ALA | ALPHA/BETA PROTEIN, ENDONUCLEASE
1brk:C (PHE7) to (GLY34) BARNASE MUTANT WITH ILE 96 REPLACED BY ALA | ALPHA/BETA PROTEIN, ENDONUCLEASE
1bsa:B (PHE7) to (GLY34) CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE | ENDONUCLEASE
1bsa:C (PHE7) to (GLY34) CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE | ENDONUCLEASE
1bsb:C (PHE7) to (GLY34) CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE | ENDONUCLEASE
1bsc:B (PHE7) to (GLY34) CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE | ENDONUCLEASE
1bsc:C (PHE7) to (GLY34) CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE | ENDONUCLEASE
1bsd:A (THR6) to (GLY34) CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE | ENDONUCLEASE
1bse:B (PHE7) to (GLY34) CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE | ENDONUCLEASE
1bse:C (PHE7) to (GLY34) CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE | ENDONUCLEASE
1bu7:A (PRO25) to (ASP63) CRYOGENIC STRUCTURE OF CYTOCHROME P450BM-3 HEME DOMAIN | FATTY ACID MONOOXYGENASE, HEMOPROTEIN, P450, OXIDOREDUCTASE
1bu7:B (PRO25) to (ASP63) CRYOGENIC STRUCTURE OF CYTOCHROME P450BM-3 HEME DOMAIN | FATTY ACID MONOOXYGENASE, HEMOPROTEIN, P450, OXIDOREDUCTASE
2pg5:A (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 N297Q | CYP2A6, P450 2A6, P450, MONOOXYGENASES, DRUG METABOLIZING ENZYME, HEME, MUTANT, INDOLE, OXIDOREDUCTASE
2pg5:B (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 N297Q | CYP2A6, P450 2A6, P450, MONOOXYGENASES, DRUG METABOLIZING ENZYME, HEME, MUTANT, INDOLE, OXIDOREDUCTASE
2pg5:C (GLN53) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 N297Q | CYP2A6, P450 2A6, P450, MONOOXYGENASES, DRUG METABOLIZING ENZYME, HEME, MUTANT, INDOLE, OXIDOREDUCTASE
2pg5:D (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 N297Q | CYP2A6, P450 2A6, P450, MONOOXYGENASES, DRUG METABOLIZING ENZYME, HEME, MUTANT, INDOLE, OXIDOREDUCTASE
2bz9:A (PRO26) to (PHE63) LIGAND-FREE STRUCTURE OF STEROL 14ALPHA-DEMETHYLASE FROM MYCOBACTERIUM TUBERCULOSIS IN P2(1) SPACE GROUP | STEROL 14ALPHA-DEMETHYLASE, P450, ELECTRON TRANSPORT, HEME, IRON, LIPID SYNTHESIS, METAL-BINDING, MONOOXYGENASE
2bz9:B (PRO26) to (ARG64) LIGAND-FREE STRUCTURE OF STEROL 14ALPHA-DEMETHYLASE FROM MYCOBACTERIUM TUBERCULOSIS IN P2(1) SPACE GROUP | STEROL 14ALPHA-DEMETHYLASE, P450, ELECTRON TRANSPORT, HEME, IRON, LIPID SYNTHESIS, METAL-BINDING, MONOOXYGENASE
1og2:B (ASP49) to (GLY91) STRUCTURE OF HUMAN CYTOCHROME P450 CYP2C9 | DRUG METABOLISM, ELECTRON TRANSPORT, OXIDOREDUCTASE, HEME, MONOOXYGENASE
1og5:A (ILE50) to (GLY91) STRUCTURE OF HUMAN CYTOCHROME P450 CYP2C9 | DRUG METABOLISM, ELECTRON TRANSPORT, OXIDOREDUCTASE, HEME, MONOOXYGENASE
1og5:B (ILE50) to (GLY91) STRUCTURE OF HUMAN CYTOCHROME P450 CYP2C9 | DRUG METABOLISM, ELECTRON TRANSPORT, OXIDOREDUCTASE, HEME, MONOOXYGENASE
2c11:D (SER626) to (ASN693) CRYSTAL STRUCTURE OF THE 2-HYDRAZINOPYRIDINE OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE | OXIDOREDUCTASE, ADHESION PROTEIN-1, 2-HYDROXYPYRIDINE, METAL-BINDING, CELL ADHESION, GLYCOPROTEIN, SIGNAL-ANCHOR, TPQ, TRANSMEMBRANE
4i3q:A (CYS58) to (VAL93) CRYSTAL STRUCTURE OF HUMAN CYP3A4 COORDINATED TO A WATER MOLECULE | HEMOPROTEIN, MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, CYTOCHROME B5, ENDOPLASMIC RETICULUM, CYTOCHROME P450, OXIDOREDUCTASE
3fn6:A (GLY114) to (ARG160) CRYSTAL STRUCTURE OF SORTASE A FROM STREPTOCOCCUS PYOGENES SEROTYPE M1 STRAIN SF370 WITH THE ACTIVE SITE CYS IN ITS SULPHENIC ACID FORM | SORTASE-FOLD, HYDROLASE
2c4b:A (PHE7) to (GLY34) INHIBITOR CYSTINE KNOT PROTEIN MCOEETI FUSED TO THE CATALYTICALLY INACTIVE BARNASE MUTANT H102A | SQUASH INHIBITOR, HYBRID MICROPROTEIN, FUSION PROTEIN, RIBONUCLEASE, ENDONUCLEASE, HYDROLASE, NUCLEASE, PROTEASE INHIBITOR, SERINE PROTEASE INHIBITOR
1cl6:A (GLU21) to (ALA55) CRYSTAL STRUCTURES OF FERRIC-NO COMPLEXES OF FUNGAL NITRIC OXIDE REDUCTASE AND ITS SER286 MUTANTS AT CRYOGENIC TEMPERATURE | NITRIC OXIDE REDUCTASE, CYTOCHROME P450NOR, OXIDOREDUCTASE
4i8v:A (HIS60) to (GLY100) HUMAN CYTOCHROME P450 1A1 IN COMPLEX WITH ALPHA-NAPHTHOFLAVONE | MONOOXYGENASE, CYTOCHROME P450, P450, CYP1A1, P450 1A1,HEME, OXIDOREDUCTASE, ARYL HYDROCARBON HYDROXYLASE
4i8v:B (ASN58) to (GLY100) HUMAN CYTOCHROME P450 1A1 IN COMPLEX WITH ALPHA-NAPHTHOFLAVONE | MONOOXYGENASE, CYTOCHROME P450, P450, CYP1A1, P450 1A1,HEME, OXIDOREDUCTASE, ARYL HYDROCARBON HYDROXYLASE
4i8v:C (HIS60) to (GLY100) HUMAN CYTOCHROME P450 1A1 IN COMPLEX WITH ALPHA-NAPHTHOFLAVONE | MONOOXYGENASE, CYTOCHROME P450, P450, CYP1A1, P450 1A1,HEME, OXIDOREDUCTASE, ARYL HYDROCARBON HYDROXYLASE
4i8v:D (HIS60) to (GLY100) HUMAN CYTOCHROME P450 1A1 IN COMPLEX WITH ALPHA-NAPHTHOFLAVONE | MONOOXYGENASE, CYTOCHROME P450, P450, CYP1A1, P450 1A1,HEME, OXIDOREDUCTASE, ARYL HYDROCARBON HYDROXYLASE
1p0v:A (PRO25) to (CYS62) F393A MUTANT HEME DOMAIN OF FLAVOCYTOCHROME P450 BM3 | CYTOCHROME P450, FATTY ACID HYDROXYLASE, MONOOXYGENASE, OXIDOREDUCTASE
1p0v:B (PRO25) to (ASP63) F393A MUTANT HEME DOMAIN OF FLAVOCYTOCHROME P450 BM3 | CYTOCHROME P450, FATTY ACID HYDROXYLASE, MONOOXYGENASE, OXIDOREDUCTASE
1p0w:A (PRO25) to (ASP63) F393W MUTANT HEME DOMAIN OF FLAVOCYTOCHROME P450 BM3 | CYTOCHROME P450, FATTY ACID HYDROXYLASE, MONOOXYGENASE, OXIDOREDUCTASE
1p0w:B (PRO25) to (ASP63) F393W MUTANT HEME DOMAIN OF FLAVOCYTOCHROME P450 BM3 | CYTOCHROME P450, FATTY ACID HYDROXYLASE, MONOOXYGENASE, OXIDOREDUCTASE
1p0x:A (PRO25) to (ASP63) F393Y MUTANT HEME DOMAIN OF FLAVOCYTOCHROME P450 BM3 | CYTOCHROME P450, FATTY ACID HYDROXYLASE, MONOOXYGENASE, OXIDOREDUCTASE
1p0x:B (PRO25) to (ASP63) F393Y MUTANT HEME DOMAIN OF FLAVOCYTOCHROME P450 BM3 | CYTOCHROME P450, FATTY ACID HYDROXYLASE, MONOOXYGENASE, OXIDOREDUCTASE
2cd8:A (TYR29) to (LEU65) CRYSTAL STRUCTURE OF YC-17-BOUND CYTOCHROME P450 PIKC (CYP107L1) | OXIDOREDUCTASE, CYTOCHROME P450, PIKC, YC-17, MACROLIDE MONOOXYGENASE, ANTIBIOTIC BIOSYNTHESIS, HEME, IRON, METAL-BINDING
2q9f:A (GLN61) to (SER99) CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 46A1 IN COMPLEX WITH CHOLESTEROL-3-SULPHATE | CYP46A1, P450 46A1, P450, MONOOXYGENASE, CHOLESTEROL METABOLIC ENZYME, OXIDOREDUCTASE, HEME, CHOLESTEROL-3-SULPHATE
2ci0:A (PRO26) to (ALA65) HIGH THROUGHPUT SCREENING AND X-RAY CRYSTALLOGRAPHY ASSISTED EVALUATION OF SMALL MOLECULE SCAFFOLDS FOR CYP51 INHIBITORS | HEME, HEME LIPID SYNTHESIS, METAL-BINDING, MONOOXYGENASE, NADP, OXIDOREDUCTASE, PROTEIN-INHIBITOR COMPLEX, STEROID BIOSYNTHESIS, STEROL BIOSYNTHESIS
2cib:A (PRO26) to (ALA65) HIGH THROUGHPUT SCREENING AND X-RAY CRYSTALLOGRAPHY ASSISTED EVALUATION OF SMALL MOLECULE SCAFFOLDS FOR CYP51 INHIBITORS | HEME, HEME LIPID SYNTHESIS, METAL-BINDING, MONOOXYGENASE, NADP, OXIDOREDUCTASE, PROTEIN-INHIBITOR COMPLEX, STEROID BIOSYNTHESIS, STEROL BIOSYNTHESIS
4xry:A (THR54) to (GLY95) HUMAN CYTOCHROME P450 2D6 BACE1 INHIBITOR 5 COMPLEX | CYP2D6, P450 2D6, CYTOCHROME P450, MONOOXYGENASE, BACE1
4xry:B (THR54) to (GLY95) HUMAN CYTOCHROME P450 2D6 BACE1 INHIBITOR 5 COMPLEX | CYP2D6, P450 2D6, CYTOCHROME P450, MONOOXYGENASE, BACE1
4xry:C (THR54) to (GLY95) HUMAN CYTOCHROME P450 2D6 BACE1 INHIBITOR 5 COMPLEX | CYP2D6, P450 2D6, CYTOCHROME P450, MONOOXYGENASE, BACE1
4xry:D (THR54) to (GLY95) HUMAN CYTOCHROME P450 2D6 BACE1 INHIBITOR 5 COMPLEX | CYP2D6, P450 2D6, CYTOCHROME P450, MONOOXYGENASE, BACE1
4xrz:A (THR54) to (GLY95) HUMAN CYTOCHROME P450 2D6 BACE1 INHIBITOR 6 COMPLEX | CYP2D6, P450 2D6, CYTOCHROME P450, MONOOXYGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX, BACE1
4xrz:B (THR54) to (GLY95) HUMAN CYTOCHROME P450 2D6 BACE1 INHIBITOR 6 COMPLEX | CYP2D6, P450 2D6, CYTOCHROME P450, MONOOXYGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX, BACE1
3g69:A (SER129) to (LYS173) THE CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE SORTASE C PROVIDES NOVEL INSIGHTS INTO CATALYSIS AS WELL AS PILIN SUBSTRATE SPECIFICITY | SORTASE, PILUS, S. PNEUMONIAE, TRANSFERASE
3g69:B (SER129) to (LYS173) THE CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE SORTASE C PROVIDES NOVEL INSIGHTS INTO CATALYSIS AS WELL AS PILIN SUBSTRATE SPECIFICITY | SORTASE, PILUS, S. PNEUMONIAE, TRANSFERASE
3t3q:A (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A6 I208S/I300F/G301A/S369G IN COMPLEX WITH PILOCARPINE | CYP2A6, CYTOCHROME P450 2A6, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3q:B (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A6 I208S/I300F/G301A/S369G IN COMPLEX WITH PILOCARPINE | CYP2A6, CYTOCHROME P450 2A6, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3q:C (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A6 I208S/I300F/G301A/S369G IN COMPLEX WITH PILOCARPINE | CYP2A6, CYTOCHROME P450 2A6, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3q:D (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A6 I208S/I300F/G301A/S369G IN COMPLEX WITH PILOCARPINE | CYP2A6, CYTOCHROME P450 2A6, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3s:A (TYR55) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH PILOCARPINE | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3s:B (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH PILOCARPINE | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3s:C (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH PILOCARPINE | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3s:D (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH PILOCARPINE | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3s:E (TYR55) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH PILOCARPINE | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3s:F (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH PILOCARPINE | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3s:G (TYR55) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH PILOCARPINE | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3s:H (GLN53) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH PILOCARPINE | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
2qrv:F (ASN291) to (SER353) STRUCTURE OF DNMT3A-DNMT3L C-TERMINAL DOMAIN COMPLEX | DNA METHYLTRANSFERASE 3A (DNMT3A) AND ITS REGULATORY FACTOR, DNA METHYLTRANSFERASE 3-LIKE PROTEIN (DNMT3L), NUCLEUS, S- ADENOSYL-L-METHIONINE, TRANSFERASE/TRANSFERASE REGULATOR COMPLEX
4iwo:A (ARG228) to (ILE284) CRYSTAL STRUCTURE AND MECHANISM OF ACTIVATION OF TBK1 | KINASE, ATP BINDING, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1pq2:A (CYS51) to (GLY91) CRYSTAL STRUCTURE OF HUMAN DRUG METABOLIZING CYTOCHROME P450 2C8 | CYTOCHROME P450, CYP2C8, MEMBRANE PROTEIN, TAXOL 6- HYDROXYLASE, OXIDOREDUCTASE
1pq2:B (CYS51) to (GLY91) CRYSTAL STRUCTURE OF HUMAN DRUG METABOLIZING CYTOCHROME P450 2C8 | CYTOCHROME P450, CYP2C8, MEMBRANE PROTEIN, TAXOL 6- HYDROXYLASE, OXIDOREDUCTASE
2d09:A (ASP27) to (VAL63) A ROLE FOR ACTIVE SITE WATER MOLECULES AND HYDROXYL GROUPS OF SUBSTRATE FOR OXYGEN ACTIVATION IN CYTOCHROME P450 158A2 | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP158A2, PROTON TRANSFER, DIOXYGEN ACTIVATION, OXIDOREDUCTASE
2d0e:A (PRO28) to (ASP66) SUBSTRATE ASSITED IN OXYGEN ACTIVATION IN CYTOCHROME P450 158A2 | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP158A2, PROTON TRANSFER, DIOXYGEN ACTIVATION, 2-HYDROXY-1,4-NAPHTHOQUINONE, OXIDOREDUCTASE
4j14:A (GLN61) to (SER99) CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 CYP46A1 WITH POSACONAZOLE BOUND | ENZYME, P450, POSACONAZOLE, OXIDOREDUCTASE, ENDOPLASMIC RETICULUM, CHOLESTEROL 24-HYDROXYLASE
3gph:A (ILE53) to (LYS94) HUMAN CYTOCHROME P450 2E1 IN COMPLEX WITH OMEGA-IMIDAZOLYL-DECANOIC ACID | CYP2E1, P450 2E1, MONOOXYGENASE, ACETAMINOPHEN, OXIDOREDUCTASE, HEME, FATTY ACID HYDROXYLASE, METAL-BINDING
3tbg:A (PRO55) to (GLY95) HUMAN CYTOCHROME P450 2D6 WITH TWO THIORIDAZINES BOUND IN ACTIVE SITE | CYTOCHROME P450, MONOOXYGENASE, THIORIDAZINE, OXIDOREDUCTASE
3tcm:A (SER356) to (ASN417) CRYSTAL STRUCTURE OF ALANINE AMINOTRANSFERASE FROM HORDEUM VULGARE | AMINOTRANSFERASE, PYRIDOXAL PHOSPHATE (PLP)-BINDING, TRANSFERASE
3tcm:B (SER356) to (ASN417) CRYSTAL STRUCTURE OF ALANINE AMINOTRANSFERASE FROM HORDEUM VULGARE | AMINOTRANSFERASE, PYRIDOXAL PHOSPHATE (PLP)-BINDING, TRANSFERASE
3tda:A (THR54) to (GLY95) COMPETITIVE REPLACEMENT OF THIORIDAZINE BY PRINOMASTAT IN CRYSTALS OF CYTOCHROME P450 2D6 | MONOOXYGENASE, HEME, PRINOMASTAT, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4j6b:A (LEU19) to (ASP57) THE 2.2 A CRYSTAL STRUCTURE OF CYP154C5 FROM NOCARDIA FARCINICA IN COMPLEX WITH PREGNENOLONE | CYTOCHROM P450, STEROID HYDROXYLATING MONOOXYGENASE, STEROID BINDING, OXIDOREDUCTASE-SUBSTRATE COMPLEX
4j6b:B (LEU19) to (ASP57) THE 2.2 A CRYSTAL STRUCTURE OF CYP154C5 FROM NOCARDIA FARCINICA IN COMPLEX WITH PREGNENOLONE | CYTOCHROM P450, STEROID HYDROXYLATING MONOOXYGENASE, STEROID BINDING, OXIDOREDUCTASE-SUBSTRATE COMPLEX
4j6c:A (ASP18) to (ASP57) THE 1.9 A CRYSTAL STRUCTURE OF CYP154C5 FROM NOCARDIA FARCINICA IN COMPLEX WITH PROGESTERONE | CYTOCHROM P450, STEROID HYDROXYLATING MONOOXYGENASE, STEROID BINDING, OXIDOREDUCTASE-SUBSTRATE COMPLEX
4j6c:B (ASP18) to (ASP57) THE 1.9 A CRYSTAL STRUCTURE OF CYP154C5 FROM NOCARDIA FARCINICA IN COMPLEX WITH PROGESTERONE | CYTOCHROM P450, STEROID HYDROXYLATING MONOOXYGENASE, STEROID BINDING, OXIDOREDUCTASE-SUBSTRATE COMPLEX
3tfh:B (THR18) to (GLU53) DMSP-DEPENDENT DEMETHYLASE FROM P. UBIQUE - APO | DEMETHYLASE, THF, TRANSFERASE
3tfi:B (THR18) to (GLU53) DMSP-DEPENDENT DEMETHYLASE FROM P. UBIQUE - WITH SUBSTRATE DMSP | DEMETHYLASE, THF, TRANSFERASE
1e9x:A (PRO26) to (ALA65) CYTOCHROME P450 14 ALPHA-STEROL DEMETHYLASE (CYP51) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 4-PHENYLIMIDAZOLE | OXIDOREDUCTASE, CYTOCHROME P450, 14 ALPHA-STEROL DEMETHYLASE, AZOLE INHIBITORS
1ea1:A (PRO26) to (PHE63) CYTOCHROME P450 14 ALPHA-STEROL DEMETHYLASE (CYP51) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH FLUCONAZOLE | OXIDOREDUCTASE, CYTOCHROME P450, 14 ALPHA-STEROL DEMETHYLASE, AZOLE INHIBITORS
4jbt:A (LEU19) to (ASP57) THE 2.2 A CRYSTAL STRUCTURE OF CYP154C5 FROM NOCARDIA FARCINICA IN COMPLEX WITH ANDROSTENEDIONE | CYTOCHROM P450, STEROID HYDROXYLATING MONOOXYGENASE, STEROID BINDING, OXIDOREDUCTASE-SUBSTRATE COMPLEX
4jbt:B (LEU19) to (ASP57) THE 2.2 A CRYSTAL STRUCTURE OF CYP154C5 FROM NOCARDIA FARCINICA IN COMPLEX WITH ANDROSTENEDIONE | CYTOCHROM P450, STEROID HYDROXYLATING MONOOXYGENASE, STEROID BINDING, OXIDOREDUCTASE-SUBSTRATE COMPLEX
3tjs:A (GLY56) to (VAL93) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN HUMAN CYTOCHROME P450 3A4 AND DESTHIAZOLYLMETHYLOXYCARBONYL RITONAVIR | MONOOXYGENASE, CYTOCHROME P450, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3gw9:A (LEU53) to (PHE90) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI BOUND TO AN INHIBITOR N-(1-(2,4- DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3, 4-OXAZIAZOL-2-YL)BENZAMIDE | STEROL 14ALPHA-DEMETHYLASE, CYP51, CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, LIPIDS, ENDOPLASMIC RETICULUM, IRON, HEME-THIOLATE PROTEIN
3gw9:D (PHE55) to (PHE90) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI BOUND TO AN INHIBITOR N-(1-(2,4- DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3, 4-OXAZIAZOL-2-YL)BENZAMIDE | STEROL 14ALPHA-DEMETHYLASE, CYP51, CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, LIPIDS, ENDOPLASMIC RETICULUM, IRON, HEME-THIOLATE PROTEIN
2rbi:A (PHE6) to (GLY33) STRUCTURE OF BINASE MUTANT HIS 101 ASN | ENDORIBONUCLEASE, MICROBIAL EXTRACELLULAR RIBONUCLEASE, PHOSPHODIESTER TRANSFERASE, HYDROLASE
2rbi:B (PHE6) to (GLY33) STRUCTURE OF BINASE MUTANT HIS 101 ASN | ENDORIBONUCLEASE, MICROBIAL EXTRACELLULAR RIBONUCLEASE, PHOSPHODIESTER TRANSFERASE, HYDROLASE
4ycg:A (SER185) to (HIS255) PRO-BONE MORPHOGENETIC PROTEIN 9 | PRO-BMP COMPLEX, MORPHOGEN, TRANSFORMING GROWTH FACTOR-BETA FAMILY, CYTOKINE
4ycg:B (SER185) to (GLU258) PRO-BONE MORPHOGENETIC PROTEIN 9 | PRO-BMP COMPLEX, MORPHOGEN, TRANSFORMING GROWTH FACTOR-BETA FAMILY, CYTOKINE
4yci:A (SER185) to (GLU256) NON-LATENT PRO-BONE MORPHOGENETIC PROTEIN 9 | PRO-BMP COMPLEX, MORPHOGEN, TRANSFORMING GROWTH FACTOR-BETA FAMILY, CYTOKINE
2rt5:A (ILE3600) to (LEU3642) STRUCTURAL INSIGHTS INTO THE RECRUITMENT OF SMRT BY THE CO-REPRESSOR SHARP UNDER PHOSPHORYLATIVE REGULATION | SHARP, SPOC DOMAIN, SMRT, PHOSPHORYLATION, TRANSCRIPTION REGULATOR
1f24:A (GLU21) to (ALA55) CRYSTAL STRUCTURE OF NO COMPLEX OF THR243ALA MUTANTS OF CYTOCHROME P450NOR | NITRIC OXIDE REDUCTASE, CYTOCHROME P450NOR, OXIDOREDUCTASE
1f4t:B (MET1) to (ASN34) THERMOPHILIC P450: CYP119 FROM SULFOLOBUS SOLFACTARICUS WITH 4- PHENYLIMIDAZOLE BOUND | P450 FOLD, OXIDOREDUCTASE
1fah:B (PRO25) to (ASP63) STRUCTURE OF CYTOCHROME P450 | MONOOXYGENASE, ELECTRON TRANSPORT, HEME
2uwh:A (PRO25) to (ASP63) CYTOCHROME P450 BM3 MUTANT IN COMPLEX WITH PALMITIC ACID | FATTY-ACID BINDING, MULTIFUNCTIONAL ENZYME, METAL-BINDING, OXIDOREDUCTASE, ELECTRON TRANSPORT, TRANSPORT, HYDROXYLASE, FLAVOPROTEIN, MONOOXYGENASE, FMN, FAD, NADP, IRON, HEME, REDOX, MEMBRANE, CYTOCHROME P450 BM3 MUTANT
2uwh:B (PRO25) to (ASP63) CYTOCHROME P450 BM3 MUTANT IN COMPLEX WITH PALMITIC ACID | FATTY-ACID BINDING, MULTIFUNCTIONAL ENZYME, METAL-BINDING, OXIDOREDUCTASE, ELECTRON TRANSPORT, TRANSPORT, HYDROXYLASE, FLAVOPROTEIN, MONOOXYGENASE, FMN, FAD, NADP, IRON, HEME, REDOX, MEMBRANE, CYTOCHROME P450 BM3 MUTANT
2uwh:C (PRO25) to (ASP63) CYTOCHROME P450 BM3 MUTANT IN COMPLEX WITH PALMITIC ACID | FATTY-ACID BINDING, MULTIFUNCTIONAL ENZYME, METAL-BINDING, OXIDOREDUCTASE, ELECTRON TRANSPORT, TRANSPORT, HYDROXYLASE, FLAVOPROTEIN, MONOOXYGENASE, FMN, FAD, NADP, IRON, HEME, REDOX, MEMBRANE, CYTOCHROME P450 BM3 MUTANT
2uwh:D (PRO25) to (ASP63) CYTOCHROME P450 BM3 MUTANT IN COMPLEX WITH PALMITIC ACID | FATTY-ACID BINDING, MULTIFUNCTIONAL ENZYME, METAL-BINDING, OXIDOREDUCTASE, ELECTRON TRANSPORT, TRANSPORT, HYDROXYLASE, FLAVOPROTEIN, MONOOXYGENASE, FMN, FAD, NADP, IRON, HEME, REDOX, MEMBRANE, CYTOCHROME P450 BM3 MUTANT
2uwh:F (PRO25) to (CYS62) CYTOCHROME P450 BM3 MUTANT IN COMPLEX WITH PALMITIC ACID | FATTY-ACID BINDING, MULTIFUNCTIONAL ENZYME, METAL-BINDING, OXIDOREDUCTASE, ELECTRON TRANSPORT, TRANSPORT, HYDROXYLASE, FLAVOPROTEIN, MONOOXYGENASE, FMN, FAD, NADP, IRON, HEME, REDOX, MEMBRANE, CYTOCHROME P450 BM3 MUTANT
3hcy:A (GLU2) to (VAL48) THE CRYSTAL STRUCTURE OF THE DOMAIN OF PUTATIVE TWO-COMPONENT SENSOR HISTIDINE KINASE PROTEIN FROM SINORHIZOBIUM MELILOTI 1021 | TWO-COMPONENT SENSOR HISTIDINE KINASE PROTEIN, STRUCTURAL GENOMICS, PSI, MCSG, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, KINASE, UNKNOWN FUNCTION
3hf2:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE I401P MUTANT OF CYTOCHROME P450 BM3 | P450 FAMILY PROTEIN FOLD, OXIDOREDUCTASE, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, TRANSPORT
3hf2:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE I401P MUTANT OF CYTOCHROME P450 BM3 | P450 FAMILY PROTEIN FOLD, OXIDOREDUCTASE, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, TRANSPORT
2v0m:B (CYS58) to (VAL93) CRYSTAL STRUCTURE OF HUMAN P450 3A4 IN COMPLEX WITH KETOCONAZOLE | METAL-BINDING, TRANSMEMBRANE, OXIDOREDUCTASE, ENDOPLASMIC RETICULUM, DRUG METABOLIZING ENZYME, KETOCONAZOL, POLYMORPHISM, MONOOXYGENASE, P450, NADP, IRON, HEME, CYP3A4, MEMBRANE, MICROSOME
2v0m:C (CYS58) to (VAL93) CRYSTAL STRUCTURE OF HUMAN P450 3A4 IN COMPLEX WITH KETOCONAZOLE | METAL-BINDING, TRANSMEMBRANE, OXIDOREDUCTASE, ENDOPLASMIC RETICULUM, DRUG METABOLIZING ENZYME, KETOCONAZOL, POLYMORPHISM, MONOOXYGENASE, P450, NADP, IRON, HEME, CYP3A4, MEMBRANE, MICROSOME
2v0m:D (CYS58) to (VAL93) CRYSTAL STRUCTURE OF HUMAN P450 3A4 IN COMPLEX WITH KETOCONAZOLE | METAL-BINDING, TRANSMEMBRANE, OXIDOREDUCTASE, ENDOPLASMIC RETICULUM, DRUG METABOLIZING ENZYME, KETOCONAZOL, POLYMORPHISM, MONOOXYGENASE, P450, NADP, IRON, HEME, CYP3A4, MEMBRANE, MICROSOME
1r9o:A (ILE47) to (GLY91) CRYSTAL STRUCTURE OF P4502C9 WITH FLURBIPROFEN BOUND | P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, OXIDOREDUCTASE, HEME
4k9v:A (GLY56) to (VAL93) COMPLEX OF CYP3A4 WITH A DESOXYRITONAVIR ANALOG | CYTOCHROME P450 3A4, ALPHA-BETA PROTEIN, CYTOCHROME P450 FOLD, MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4k9x:A (PHE57) to (VAL93) COMPLEX OF HUMAN CYP3A4 WITH A DESOXYRITONAVIR ANALOG | CYTOCHROME P450 3A4, ALPHA-BETA PROTEIN, CYTOCHROME P450 FOLD, MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
2f4y:A (PHE5) to (GLY32) BARNASE CROSS-LINKED WITH GLUTARALDEHYDE | DENATURATION, LYSOZYME, BARNASE, CROSS-LINKED CRYSTALS, GLUTARALDEHYDE, UREA, THIOUREA, BROMOETHANOL, HYDROLASE
2f4y:B (PHE5) to (GLY32) BARNASE CROSS-LINKED WITH GLUTARALDEHYDE | DENATURATION, LYSOZYME, BARNASE, CROSS-LINKED CRYSTALS, GLUTARALDEHYDE, UREA, THIOUREA, BROMOETHANOL, HYDROLASE
2f4y:C (PHE5) to (GLY32) BARNASE CROSS-LINKED WITH GLUTARALDEHYDE | DENATURATION, LYSOZYME, BARNASE, CROSS-LINKED CRYSTALS, GLUTARALDEHYDE, UREA, THIOUREA, BROMOETHANOL, HYDROLASE
2f56:A (PHE5) to (GLY32) BARNASE CROSS-LINKED WITH GLUTARALDEHYDE SOAKED IN 6M UREA | DENATURATION, LYSOZYME, BARNASE, CROSS-LINKED CRYSTALS, GLUTARALDEHYDE, UREA, THIOUREA, BROMOETHANOL, HYDROLASE
2f56:B (PHE5) to (GLY32) BARNASE CROSS-LINKED WITH GLUTARALDEHYDE SOAKED IN 6M UREA | DENATURATION, LYSOZYME, BARNASE, CROSS-LINKED CRYSTALS, GLUTARALDEHYDE, UREA, THIOUREA, BROMOETHANOL, HYDROLASE
2f56:C (PHE5) to (GLY32) BARNASE CROSS-LINKED WITH GLUTARALDEHYDE SOAKED IN 6M UREA | DENATURATION, LYSOZYME, BARNASE, CROSS-LINKED CRYSTALS, GLUTARALDEHYDE, UREA, THIOUREA, BROMOETHANOL, HYDROLASE
4kew:A (PRO25) to (ASP63) STRUCTURE OF THE A82F BM3 HEME DOMAIN IN COMPLEX WITH OMEPRAZOLE | P450, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4kew:B (PRO25) to (ASP63) STRUCTURE OF THE A82F BM3 HEME DOMAIN IN COMPLEX WITH OMEPRAZOLE | P450, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4kf0:A (PRO25) to (CYS62) STRUCTURE OF THE A82F P450 BM3 HEME DOMAIN | P450, MONOOXYGENASE, OXIDOREDUCTASE
4kf0:B (PRO25) to (ASP63) STRUCTURE OF THE A82F P450 BM3 HEME DOMAIN | P450, MONOOXYGENASE, OXIDOREDUCTASE
4key:A (PRO25) to (ASP63) STRUCTURE OF P450 BM3 A82F F87V IN COMPLEX WITH OMEPRAZOLE | P450 HEME DOMAIN, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4key:B (PRO25) to (ASP63) STRUCTURE OF P450 BM3 A82F F87V IN COMPLEX WITH OMEPRAZOLE | P450 HEME DOMAIN, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4kf2:A (PRO25) to (CYS62) STRUCTURE OF THE P4509 BM3 A82F F87V HEME DOMAIN | P450, MONOOXYGENASE, OXIDOREDUCTASE
4kf2:B (PRO25) to (ASP63) STRUCTURE OF THE P4509 BM3 A82F F87V HEME DOMAIN | P450, MONOOXYGENASE, OXIDOREDUCTASE
2fdu:A (MET54) to (ALA95) MICROSOMAL P450 2A6 WITH THE INHIBITOR N,N-DIMETHYL(5- (PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdu:B (MET54) to (ALA95) MICROSOMAL P450 2A6 WITH THE INHIBITOR N,N-DIMETHYL(5- (PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdu:C (MET54) to (ALA95) MICROSOMAL P450 2A6 WITH THE INHIBITOR N,N-DIMETHYL(5- (PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdu:D (MET54) to (ALA95) MICROSOMAL P450 2A6 WITH THE INHIBITOR N,N-DIMETHYL(5- (PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdv:A (MET54) to (ALA95) MICROSOMAL P450 2A6 WITH THE INHIBITOR N-METHYL(5-(PYRIDIN- 3-YL)FURAN-2-YL)METHANAMINE BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdv:B (GLN53) to (ALA95) MICROSOMAL P450 2A6 WITH THE INHIBITOR N-METHYL(5-(PYRIDIN- 3-YL)FURAN-2-YL)METHANAMINE BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdv:C (GLN53) to (ALA95) MICROSOMAL P450 2A6 WITH THE INHIBITOR N-METHYL(5-(PYRIDIN- 3-YL)FURAN-2-YL)METHANAMINE BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdv:D (MET54) to (ALA95) MICROSOMAL P450 2A6 WITH THE INHIBITOR N-METHYL(5-(PYRIDIN- 3-YL)FURAN-2-YL)METHANAMINE BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdw:A (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH THE INHIBITOR (5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdw:B (GLN53) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH THE INHIBITOR (5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdw:C (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH THE INHIBITOR (5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdw:D (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH THE INHIBITOR (5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2ve4:A (ASP34) to (PHE69) SUBSTRATE FREE CYANOBACTERIAL CYP120A1 | OXIDOREDUCTASE, MONOOXYGENASE, METAL-BINDING, HEME, IRON
2ve3:A (PHE35) to (PHE69) RETINOIC ACID BOUND CYANOBACTERIAL CYP120A1 | OXIDOREDUCTASE, MONOOXYGENASE, METAL-BINDING, HEME, IRON
2ve3:B (GLY36) to (LEU68) RETINOIC ACID BOUND CYANOBACTERIAL CYP120A1 | OXIDOREDUCTASE, MONOOXYGENASE, METAL-BINDING, HEME, IRON
1s1f:A (ASP27) to (ASP66) CRYSTAL STRUCTURE OF STREPTOMYCES COELICOLOR A3(2) CYP158A2 FROM ANTIBIOTIC BIOSYNTHETIC PATHWAYS | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP158A2, ANTIBIOTIC BIOSYNTHESIS, OXIDOREDUCTASE
1ged:A (GLU21) to (ALA55) A POSITIVE CHARGE ROUTE FOR THE ACCESS OF NADH TO HEME FORMED IN THE DISTAL HEME POCKET OF CYTOCHROME P450NOR | CYTOCHROME P450NOR, NITRIC OXIDE REDUCTASE, X-RAY CRYSTALLOGRAPHY, OXIDOREDUCTASE
2vku:A (PRO26) to (ALA65) 4,4'-DIHYDROXYBENZOPHENONE MIMICS STEROL SUBSTRATE IN THE BINDING SITE OF STEROL 14ALPHA-DEMETHYLASE (CYP51) IN THE X-RAY STRUCTURE OF THE COMPLEX | STEROID BIOSYNTHESIS, CYP51-4, CYTOPLASM, ALPHA-BETA, HEME CO-FACTOR, LIPID SYNTHESIS, STEROL BIOSYNTHESIS, 4'- DIHYDROXYBENZOPHENONE COMPLEX, NADP, IRON, HEME, MONOOXYGENASE, METAL-BINDING, OXIDOREDUCTASE
4zdz:A (PRO76) to (VAL112) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) Y140F MUTANT COMPLEXED WITH FLUCONAZOLE | CYP51, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, RESISTANCE MUTATION
4zf8:A (PRO25) to (ASP63) CYTOCHROME P450 PENTAMUTANT FROM BM3 WITH BOUND METYRAPONE | CYTOCHROME P450, HEME OXIDASE DOMAIN, OXIDOREDUCTASE, BACILLUS MEGATERIUM
4zfa:A (PRO25) to (ASP63) CYTOCHROME P450 WILD TYPE FROM BM3 WITH BOUND PEG | CYTOCHROME P450, HEME OXIDASE DOMAIN, OXIDOREDUCTASE, BACILLUS MEGATERIUM
4zfb:A (PRO25) to (ASP63) CYTOCHROME P450 PENTAMUTANT FROM BM3 BOUND TO PALMITIC ACID | CYTOCHROME P450, HEME OXIDASE DOMAIN, OXIDOREDUCTASE, BACILLUS MEGATERIUM
1se6:A (PRO28) to (ASP66) CRYSTAL STRUCTURE OF STREPTOMYCES COELICOLOR A3(2) CYP158A2 FROM ANTIBIOTIC BIOSYNTHETIC PATHWAYS | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP158A2, ANTIBIOTIC BIOSYNTHESIS, OXIDOREDUCTASE
1se6:B (PRO28) to (ASP66) CRYSTAL STRUCTURE OF STREPTOMYCES COELICOLOR A3(2) CYP158A2 FROM ANTIBIOTIC BIOSYNTHETIC PATHWAYS | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP158A2, ANTIBIOTIC BIOSYNTHESIS, OXIDOREDUCTASE
4kpa:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM-3 IN COMPLEX WITH N- PALMITOYLGLYCINE (NPG) | HEME-DEPENDENT STEREOSPECIFIC OXIDATION OF SUBSTRATES, OXIDOREDUCTASE
2vn0:A (ILE50) to (GLY91) CYP2C8DH COMPLEXED WITH TROGLITAZONE | OXIDOREDUCTASE, ELECTRON TRANSPORT, ENDOPLASMIC RETICULUM, METAL-BINDING, PALMITIC ACID, HUMAN P450 2C8, TROGLITAZONE, POLYMORPHISM, MONOOXYGENASE, IRON, HEME, CYP2C8, MEMBRANE, MICROSOME, MONOOXYGENASES, INHIBITOR COMPLEX
4zgx:A (LEU64) to (ASP104) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
4zgx:B (LEU64) to (ASP104) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
4zgx:C (HIS63) to (ASP104) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
4zgx:D (LEU64) to (ASP104) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
4zgx:E (LEU64) to (SER105) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
4zgx:F (LEU64) to (ASP104) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
4zgx:G (LEU64) to (ASP104) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
4zgx:H (LEU64) to (ASP104) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
4zgx:J (HIS63) to (VAL103) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
4zgx:L (LEU64) to (ASP104) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
1gou:A (THR5) to (GLY33) RIBONUCLEASE BINASE (G SPECIFIC ENDONUCLEASE) UNLIGANDED FORM | HYDROLASE, ENDORIBONUCLEASE, NUCLEASE
1goy:A (THR5) to (GLY33) HYDROLASE(ENDORIBONUCLEASE)RIBONUCLEASE BI (G SPECIFIC ENDONUCLEASE) (E.C.3.1.27.-) COMPLEXED WITH GUANOSINE-3'-PHOSPHATE (3'-GMP) | HYDROLASE, ENDORIBONUCLEASE, NUCLEASE
1smi:A (PRO25) to (ASP63) A SINGLE MUTATION OF P450 BM3 INDUCES THE CONFORMATIONAL REARRANGEMENT SEEN UPON SUBSTRATE-BINDING IN WILD-TYPE ENZYME | MONOOXYGENASE; FATTY ACID OXYGENASE; CYTOCHROME P450; SUBSTRATE BINDING, OXIDOREDUCTASE
1smi:B (PRO25) to (CYS62) A SINGLE MUTATION OF P450 BM3 INDUCES THE CONFORMATIONAL REARRANGEMENT SEEN UPON SUBSTRATE-BINDING IN WILD-TYPE ENZYME | MONOOXYGENASE; FATTY ACID OXYGENASE; CYTOCHROME P450; SUBSTRATE BINDING, OXIDOREDUCTASE
4l40:A (TYR23) to (ASN60) STRUCTURE OF THE P450 OLET WITH A C20 FATTY ACID SUBSTRATE BOUND | CYTOCHROME P450, PEROXYGENASE, FATTY ACID DECARBOXYLASE, OXIDOREDUCTASE
4l54:A (TYR23) to (ASN60) STRUCTURE OF CYTOCHROME P450 OLET, LIGAND-FREE | PEROXIDASE, DECARBOXYLASE, OXIDOREDUCTASE
2w0a:A (PRO26) to (ALA65) CYP51 OF M. TUBERCULOSIS BOUND TO AN INHIBITOR N-[(1S)-2-METHYL-1-(PYRIDIN-4-YLCARBAMOYL)PROPYL] CYCLOHEXANECARBOXAMIDE | STEROID BIOSYNTHESIS, PROTEIN-INHIBITOR COMPLEX, METAL-BINDING, OXIDOREDUCTASE, LIPID SYNTHESIS, NADP, IRON, HEME, CYTOPLASM, MONOOXYGENASE, X-RAY DIFFRACTION, STEROL BIOSYNTHESIS
2w0b:A (PRO26) to (ALA65) CYP51 OF M. TUBERCULOSIS BOUND TO AN INHIBITOR 3-{[(4- METHYLPHENYL)SULFONYL]AMINO}PROPYL PYRIDIN-4-YLCARBAMATE | STEROID BIOSYNTHESIS, PROTEIN-INHIBITOR COMPLEX, METAL-BINDING, OXIDOREDUCTASE, LIPID SYNTHESIS, NADP, IRON, HEME, CYTOPLASM, MONOOXYGENASE, X-RAY DIFFRACTION, STEROL BIOSYNTHESIS
1h5z:A (PRO26) to (ARG64) CYTOCHROME P450 14 ALPHA-STEROL DEMETHYLASE (CYP51) FROM MYCOBACTERIUM TUBERCULOSIS IN FERRIC LOW-SPIN STATE | OXIDOREDUCTASE, CYTOCHROME P450, 14 ALPHA-STEROL DEMETHYLASE, FERRIC LOW-SPIN, STEROL BIOSYNTHESIS, MONOOXYGENASE, ELECTRON TRANSPORT
2w1j:A (ALA101) to (LYS145) CRYSTAL STRUCTURE OF SORTASE C-1 (SRTC-1) FROM STREPTOCOCCUS PNEUMONIAE | PATHOGENICITY, TRANSFERASE
2w1j:B (ALA101) to (LYS145) CRYSTAL STRUCTURE OF SORTASE C-1 (SRTC-1) FROM STREPTOCOCCUS PNEUMONIAE | PATHOGENICITY, TRANSFERASE
1tqn:A (CYS58) to (VAL93) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 3A4 | P450, CYP3A4, MONOOXYGENASE, DRUG METABOLIZING ENZYME, OXIDOREDUCTASE, HEME
3iw1:A (VAL40) to (SER86) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS CYTOCHROME P450 CYP125 IN COMPLEX WITH ANDROSTENEDIONE | ANDROSTENEDIONE, CHOLESTEROL, MONOXYGENASE, TUBERCULOSIS, CYTOCHROME P450, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE
2hi4:A (HIS62) to (GLY102) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 1A2 IN COMPLEX WITH ALPHA-NAPHTHOFLAVONE | CYP1A2, P450 1A2, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, ALPHA-NAPHTHOFLAVONE, BENZO(H)FLAVONE, 7,8- BENZOFLAVONE, OXIDOREDUCTASE, HEME
2wiy:A (TYR181) to (ALA213) CYTOCHROME P450 XPLA HEME DOMAIN P21212 | CYT-P450, HEME, RDX, BIOREMEDIATION, ELECTRON TRANSPORT
5a1p:A (GLY56) to (VAL93) CRYSTAL STRUCTURE OF CYTOCHROME P450 3A4 BOUND TO PROGESTERONE AND CITRATE | OXIDOREDUCTASE, CYTOCHROME P450 3A4, CYP3A4, MONOOXYGENASE, PROGESTERONE, CITRATE
2hpd:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF HEMOPROTEIN DOMAIN OF P450BM-3, A PROTOTYPE FOR MICROSOMAL P450'S | OXIDOREDUCTASE(OXYGENASE)
1u13:A (PRO26) to (PHE63) CRYSTAL STRUCTURE ANALYSIS OF THE C37L/C151T/C442A-TRIPLE MUTANT OF CYP51 FROM MYCOBACTERIUM TUBERCULOSIS | ALPHA-BETA, HEME CO-FACTOR, OXIDOREDUCTASE
4lxj:A (LYS75) to (VAL112) SACCHAROMYCES CEREVISIAE LANOSTEROL 14-ALPHA DEMETHYLASE WITH LANOSTEROL BOUND | CYTOCHROME P450, OXIDOREDUCTASE
2wts:A (ALA101) to (LYS145) CRYSTAL STRUCTURE OF SORTASE C-1 (SRTC-1) MUTANT H131D FROM S. PNEUMONIAE | TRANSFERASE, PILI, PATHOGENICITY
2wts:B (ALA101) to (LYS145) CRYSTAL STRUCTURE OF SORTASE C-1 (SRTC-1) MUTANT H131D FROM S. PNEUMONIAE | TRANSFERASE, PILI, PATHOGENICITY
5a5j:A (ILE47) to (GLY91) CYTOCHROME 2C9 P450 INHIBITOR COMPLEX | OXIDOREDUCTASE
2iag:A (ALA51) to (GLU89) CRYSTAL STRUCTURE OF HUMAN PROSTACYCLIN SYNTHASE | PROSTACYCLIN SYNTHASE, CLASS III CYTOCHORME P450, HEMOPROTEIN, CYP8A1, ISOMERASE
2wx2:A (PRO52) to (PHE90) X-RAY STRUCTURE OF CYP51 FROM THE HUMAN PATHOGEN TRYPANOSOMA CRUZI IN COMPLEX WITH FLUCONAZOLE | P450, HEME, IRON, METAL-BINDING, METHYLTRANSFERASE, ERGOSTEROL BIOSYNTHESIS, OXIDOREDUCTASE
2ij2:A (PRO25) to (CYS62) ATOMIC STRUCTURE OF THE HEME DOMAIN OF FLAVOCYTOCHROME P450- BM3 | CYTOCHROME P450, P450BM3, MONOXYGENASE, HEME BINDING PROTEIN, ATOMIC RESOLUTION, OXIDOREDUCTASE
2ij2:B (PRO25) to (ASP63) ATOMIC STRUCTURE OF THE HEME DOMAIN OF FLAVOCYTOCHROME P450- BM3 | CYTOCHROME P450, P450BM3, MONOXYGENASE, HEME BINDING PROTEIN, ATOMIC RESOLUTION, OXIDOREDUCTASE
2ij3:A (PRO25) to (ASP63) STRUCTURE OF THE A264H MUTANT OF CYTOCHROME P450 BM3 | HEME LIGATION, HISTIDINE LIGATION, CYTOCHROME P450, P450 BM3, OXIDOREDUCTASE
2ij3:B (PRO25) to (ASP63) STRUCTURE OF THE A264H MUTANT OF CYTOCHROME P450 BM3 | HEME LIGATION, HISTIDINE LIGATION, CYTOCHROME P450, P450 BM3, OXIDOREDUCTASE
1izo:B (LYS26) to (ASP60) CYTOCHROME P450 BS BETA COMPLEXED WITH FATTY ACID | HEME PROTEIN, PROTEIN-FATTY ACID COMPLEX, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, OXIDOREDUCTASE
1izo:C (LEU23) to (ASP60) CYTOCHROME P450 BS BETA COMPLEXED WITH FATTY ACID | HEME PROTEIN, PROTEIN-FATTY ACID COMPLEX, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, OXIDOREDUCTASE
2x5l:A (ALA41) to (SER86) X-RAY STRUCTURE OF THE SUBSTRATE-FREE MYCOBACTERIUM TUBERCULOSIS CYTOCHROME P450 CYP125, ALTERNATIVE CRYSTAL FORM | OXIDOREDUCTASE, CHOLESTEROL DEGRADATION, MONOOXYGENASE, METAL-BINDING
5ajr:A (PHE55) to (PHE90) STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA CRUZI IN COMPLEX WITH THE 1-TETRAZOLE DERIVATIVE VT-1161 ((R)-2-( 2,4-DIFLUOROPHENYL)-1,1-DIFLUORO-3-(1H-TETRAZOL-1-YL)-1-(5- (4-(2,2,2-TRIFLUOROETHOXY)PHENYL)PYRIDIN-2-YL)PROPAN-2-OL) | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE
2x7y:A (PRO25) to (ASP63) P450 BM3 F87A IN COMPLEX WITH DMSO | ELECTRON TRANSPORT, OXIDOREDUCTASE, DMSO-INHIBITION, METAL-BINDING
2x7y:B (PRO25) to (CYS62) P450 BM3 F87A IN COMPLEX WITH DMSO | ELECTRON TRANSPORT, OXIDOREDUCTASE, DMSO-INHIBITION, METAL-BINDING
2x80:B (PRO25) to (ASP63) P450 BM3 F87A IN COMPLEX WITH DMSO | ELECTRON TRANSPORT, OXIDOREDUCTASE, DMSO-INHIBITION, METAL-BINDING
2j0d:B (CYS58) to (VAL93) CRYSTAL STRUCTURE OF HUMAN P450 3A4 IN COMPLEX WITH ERYTHROMYCIN | POLYMORPHISM, ERYTHROMYCIN, MONOOXYGENASE, METAL-BINDING, TRANSMEMBRANE, OXIDOREDUCTASE, ENDOPLASMIC RETICULUM, DRUG METABOLIZING ENZYME, P450, NADP, IRON, HEME, CYP3A4, MEMBRANE, MICROSOME
2j1m:A (PRO25) to (CYS62) P450 BM3 HEME DOMAIN IN COMPLEX WITH DMSO | OXIDOREDUCTASE, DMSO-INHIBITION, P450, IRON, HEME, ORGANIC SOLVENT, FLAVOPROTEIN, MONOOXYGENASE, METAL-BINDING, MEMBRANE
2j1m:B (PRO25) to (ASP63) P450 BM3 HEME DOMAIN IN COMPLEX WITH DMSO | OXIDOREDUCTASE, DMSO-INHIBITION, P450, IRON, HEME, ORGANIC SOLVENT, FLAVOPROTEIN, MONOOXYGENASE, METAL-BINDING, MEMBRANE
1vhu:A (ALA62) to (PHE127) CRYSTAL STRUCTURE OF A PUTATIVE PHOSPHOESTERASE | STRUCTURAL GENOMICS, UNKNOWN FUNCTION
2j4s:A (PRO25) to (CYS62) P450 BM3 HEME DOMAIN IN COMPLEX WITH DMSO | FLAVOPROTEIN, MONOOXYGENASE, METAL-BINDING, P450, IRON, HEME, OXIDOREDUCTASE, DMSO-INHIBITION, ORGANIC SOLVENT
2j4s:B (VAL26) to (ALA61) P450 BM3 HEME DOMAIN IN COMPLEX WITH DMSO | FLAVOPROTEIN, MONOOXYGENASE, METAL-BINDING, P450, IRON, HEME, OXIDOREDUCTASE, DMSO-INHIBITION, ORGANIC SOLVENT
3wsp:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF P450BM3 WITH N-PERFLUORONONANOYL-L-TRYPTOPHAN | CYTOCHROME P450, OXIDOREDUCTASE
3wsp:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF P450BM3 WITH N-PERFLUORONONANOYL-L-TRYPTOPHAN | CYTOCHROME P450, OXIDOREDUCTASE
1jpz:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF A COMPLEX OF THE HEME DOMAIN OF P450BM- 3 WITH N-PALMITOYLGLYCINE | PROTEIN-SUBSTRATE COMPLEX, HEMEPROTEIN, OXIDOREDUCTASE
1jpz:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF A COMPLEX OF THE HEME DOMAIN OF P450BM- 3 WITH N-PALMITOYLGLYCINE | PROTEIN-SUBSTRATE COMPLEX, HEMEPROTEIN, OXIDOREDUCTASE
1w0g:A (CYS58) to (LYS96) CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 3A4 | OXIDOREDUCTASE, NIFEDIPINE OXIDASE, CYTOCHROME P450, ELECTRON TRANSPORT, MONOOXYGENASE
3zg2:A (PHE55) to (PHE90) STEROL 14 ALPHA-DEMETHYLASE (CYP51) FROM TRYPANOSOMA CRUZI IN COMPLEX WITH THE PYRIDINE INHIBITOR (S)-2-(4-CHLOROPHENYL)-2- (PYRIDIN-3-YL)-1-(4-(4-(TRIFLUOROMETHYL)PHENYL)PIPERAZIN-1-YL) ETHANONE (EPL-BS1246,UDO) | OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE, INHIBITOR
4nkv:A (MET49) to (GLY90) HUMAN STEROIDOGENIC CYTOCHROME P450 17A1 MUTANT A105L WITH INHIBITOR ABIRATERONE | HEME PROTEIN, MONOOXYGENASE, STEROID 17ALPHA-HYDROXYLASE, STEROID C17,20 LYASE, NADPH-CYTOCHROME P450 REDUCTASE, CYTOCHROME B5, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE, LYASE-INHIBITOR COMPLEX
4nkv:B (MET49) to (GLY90) HUMAN STEROIDOGENIC CYTOCHROME P450 17A1 MUTANT A105L WITH INHIBITOR ABIRATERONE | HEME PROTEIN, MONOOXYGENASE, STEROID 17ALPHA-HYDROXYLASE, STEROID C17,20 LYASE, NADPH-CYTOCHROME P450 REDUCTASE, CYTOCHROME B5, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE, LYASE-INHIBITOR COMPLEX
4nky:A (MET49) to (GLY90) HUMAN STEROIDOGENIC CYTOCHROME P450 17A1 MUTANT A105L WITH SUBSTRATE 17ALPHA-HYDROXYPROGESTERONE | HEME PROTEIN, MONOOXYGENASE, STEROID 17ALPHA-HYDROXYLASE, STEROID C17,20 LYASE, NADPH-CYTOCHROME P450 REDUCTASE, CYTOCHROME B5, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE, LYASE
4nky:B (MET49) to (GLY90) HUMAN STEROIDOGENIC CYTOCHROME P450 17A1 MUTANT A105L WITH SUBSTRATE 17ALPHA-HYDROXYPROGESTERONE | HEME PROTEIN, MONOOXYGENASE, STEROID 17ALPHA-HYDROXYLASE, STEROID C17,20 LYASE, NADPH-CYTOCHROME P450 REDUCTASE, CYTOCHROME B5, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE, LYASE
4nkz:B (MET49) to (GLY90) HUMAN STEROIDOGENIC CYTOCHROME P450 17A1 MUTANT A105L WITH SUBSTRATE 17ALPHA-HYDROXYPREGNENOLONE | HEME PROTEIN, MONOOXYGENASE, STEROID 17ALPHA-HYDROXYLASE, STEROID C17,20 LYASE, NADPH-CYTOCHROME P450 REDUCTASE, CYTOCHROME B5, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE, LYASE
5c0o:F (HIS36) to (HIS69) M1A58 TRNA METHYLTRANSFERASE MUTANT - Y78A | TRANSFERASE, TRMI, M1A
1x1w:B (THR6) to (GLY34) WATER-MEDIATE INTERACTION AT APROTEIN-PROTEIN INTERFACE | RNASE-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE/PROTEIN BINDING COMPLEX
1x1w:C (PHE7) to (GLY34) WATER-MEDIATE INTERACTION AT APROTEIN-PROTEIN INTERFACE | RNASE-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE/PROTEIN BINDING COMPLEX
1x1x:C (GLY9) to (GLY34) WATER-MEDIATE INTERACTION AT APROTEIN-PROTEIN INTERFACE | RNASE-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE/PROTEIN BINDING COMPLEX
1x1y:B (PHE7) to (GLY34) WATER-MEDIATE INTERACTION AT APROTEIN-PROTEIN INTERFACE | RNASE-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE/PROTEIN BINDING COMPLEX
4ny4:A (GLY56) to (CYS98) CRYSTAL STRUCTURE OF CYP3A4 IN COMPLEX WITH AN INHIBITOR | CYTOCHROME P-450, CYP3A4, INHIBITOR, STRUCTURE-BASED DRUG DESIGN, DRUG METABOLISM, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4nz2:B (ILE50) to (GLY91) CRYSTAL STRUCTURE OF CYP2C9 IN COMPLEX WITH AN INHIBITOR | CYTOCHROME P-450, CYP2C9, INHIBITOR, STRUCTURE-BASED DRUG DESIGN, DRUG METABOLISM, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
2nnb:A (PRO25) to (ASP63) THE Q403K MUTNAT HEME DOMAIN OF FLAVOCYTOCHROME P450 BM3 | FLAVOCYTOCHROME P450, HEME DOMAIN, FATTY-ACID HYDROXYLASE, OXIDOREDUCTASE
2nnb:B (PRO25) to (CYS62) THE Q403K MUTNAT HEME DOMAIN OF FLAVOCYTOCHROME P450 BM3 | FLAVOCYTOCHROME P450, HEME DOMAIN, FATTY-ACID HYDROXYLASE, OXIDOREDUCTASE
2nni:A (ILE50) to (GLY91) CYP2C8DH COMPLEXED WITH MONTELUKAST | CYP2C8; HUMAN P450 2C8; MONOOXYGENASES; MONTELUKAST; SINGULAIR; INHIBITOR COMPLEX; PALMITIC ACI, OXIDOREDUCTASE,ELECTRON TRANSPORT
2nnj:A (ILE50) to (GLY91) CYP2C8DH COMPLEXED WITH FELODIPINE | CYP2C8; HUMAN P450 2C8; MONOOXYGENASES; FELODIPINE; PLENDIL; INHIBITOR COMPLEX; PALMITIC ACID, OXIDOREDUCTASE,ELECTRON TRANSPORT
4o4p:A (PRO25) to (ASP63) STRUCTURE OF P450 BM3 A82F F87V IN COMPLEX WITH S-OMEPRAZOL | P450, MONOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4o4p:B (PRO25) to (ASP63) STRUCTURE OF P450 BM3 A82F F87V IN COMPLEX WITH S-OMEPRAZOL | P450, MONOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4o8l:A (ASP114) to (ASN159) STRUCTURE OF SORTASE A FROM STREPTOCOCCUS PNEUMONIAE | 8-STRANDED BETA BARREL, SORTASE-FOLD, CYSTEINE TRANSPEPTIDASE, HYDROLASE
3jzt:A (LYS89) to (GLY136) STRUCTURE OF A CUBIC CRYSTAL FORM OF X (ADRP) DOMAIN FROM FCOV WITH ADP-RIBOSE | ADRP DOMAIN, X DOMAIN, MACRO DOMAIN, ADP-RIBOSE, CORONAVIRUS, RNA BINDING PROTEIN
3jzt:E (LYS89) to (GLY136) STRUCTURE OF A CUBIC CRYSTAL FORM OF X (ADRP) DOMAIN FROM FCOV WITH ADP-RIBOSE | ADRP DOMAIN, X DOMAIN, MACRO DOMAIN, ADP-RIBOSE, CORONAVIRUS, RNA BINDING PROTEIN
3jzt:G (LYS89) to (GLY136) STRUCTURE OF A CUBIC CRYSTAL FORM OF X (ADRP) DOMAIN FROM FCOV WITH ADP-RIBOSE | ADRP DOMAIN, X DOMAIN, MACRO DOMAIN, ADP-RIBOSE, CORONAVIRUS, RNA BINDING PROTEIN
3jzt:H (LYS89) to (GLY136) STRUCTURE OF A CUBIC CRYSTAL FORM OF X (ADRP) DOMAIN FROM FCOV WITH ADP-RIBOSE | ADRP DOMAIN, X DOMAIN, MACRO DOMAIN, ADP-RIBOSE, CORONAVIRUS, RNA BINDING PROTEIN
2nz5:A (ASP30) to (ASP69) STRUCTURE AND FUNCTION STUDIES OF CYTOCHROME P450 158A1 FROM STREPTOMYCES COELICOLOR A3(2) | STREPTOMYCES; CYTOCHROME P450 OXIDOREDUCTASE; CYP158A1; FLAVIOLIN; C- C COUPLING ACTIVITY, OXIDOREDUCTASE
3k9v:A (GLN82) to (TYR119) CRYSTAL STRUCTURE OF RAT MITOCHONDRIAL P450 24A1 S57D IN COMPLEX WITH CHAPS | MITOCHONDRIAL CYTOCHROME P450, MONOTOPIC MEMBRANE PROTEIN, MONOOXYGENASE, VITAMIN D HORMONE METABOLISM, ADRENODOXIN, OXIDOREDUCTASE
3k9v:B (GLN82) to (ARG120) CRYSTAL STRUCTURE OF RAT MITOCHONDRIAL P450 24A1 S57D IN COMPLEX WITH CHAPS | MITOCHONDRIAL CYTOCHROME P450, MONOTOPIC MEMBRANE PROTEIN, MONOOXYGENASE, VITAMIN D HORMONE METABOLISM, ADRENODOXIN, OXIDOREDUCTASE
3k9y:A (GLN82) to (GLU122) CRYSTAL STRUCTURE OF RAT MITOCHONDRIAL P450 24A1 S57D IN COMPLEX WITH CYMAL-5 | MITOCHONDRIAL CYTOCHROME P450, MONOTOPIC MEMBRANE PROTEIN, MONOOXYGENASE, VITAMIN D HORMONE METABOLISM, ADRENODOXIN, OXIDOREDUCTASE
3k9y:B (GLN82) to (GLU122) CRYSTAL STRUCTURE OF RAT MITOCHONDRIAL P450 24A1 S57D IN COMPLEX WITH CYMAL-5 | MITOCHONDRIAL CYTOCHROME P450, MONOTOPIC MEMBRANE PROTEIN, MONOOXYGENASE, VITAMIN D HORMONE METABOLISM, ADRENODOXIN, OXIDOREDUCTASE
3kch:A (PHE7) to (GLY34) BARANASE CROSSLINKED BY GLUTARALDEHYDE | RIBONUCLEASE, MICROBIAL RIBONUCLEASE, GLUTARALDEHYDE, CROSSLINK, ENDONUCLEASE, HYDROLASE, NUCLEASE, SECRETED
3kch:B (PHE7) to (GLY34) BARANASE CROSSLINKED BY GLUTARALDEHYDE | RIBONUCLEASE, MICROBIAL RIBONUCLEASE, GLUTARALDEHYDE, CROSSLINK, ENDONUCLEASE, HYDROLASE, NUCLEASE, SECRETED
3kch:C (PHE7) to (GLY34) BARANASE CROSSLINKED BY GLUTARALDEHYDE | RIBONUCLEASE, MICROBIAL RIBONUCLEASE, GLUTARALDEHYDE, CROSSLINK, ENDONUCLEASE, HYDROLASE, NUCLEASE, SECRETED
3kx3:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF BACILLUS MEGATERIUM BM3 HEME DOMAIN MUTANT L86E | CYTOCHROME P450, L86E MUTANT, HEME DOMAIN, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3kx3:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF BACILLUS MEGATERIUM BM3 HEME DOMAIN MUTANT L86E | CYTOCHROME P450, L86E MUTANT, HEME DOMAIN, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3kx4:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF BACILLUS MEGATERIUM BM3 HEME DOMAIN MUTANT I401E | CYTOCHROME P450, I401E MUTANT, HEME DOMAIN, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3kx4:B (PRO25) to (CYS62) CRYSTAL STRUCTURE OF BACILLUS MEGATERIUM BM3 HEME DOMAIN MUTANT I401E | CYTOCHROME P450, I401E MUTANT, HEME DOMAIN, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
5de9:A (PRO28) to (ASP66) THE ROLE OF ILE87 OF CYP158A2 IN OXIDATIVE COUPLING REACTION | CYP158A2, CYTOCHROME P450, OXIDATIVE COUPLING REACTION, OXIDOREDUCTASE
5de9:B (PRO28) to (ASP66) THE ROLE OF ILE87 OF CYP158A2 IN OXIDATIVE COUPLING REACTION | CYP158A2, CYTOCHROME P450, OXIDATIVE COUPLING REACTION, OXIDOREDUCTASE
1yqo:A (PRO25) to (ASP63) T268A MUTANT HEME DOMAIN OF FLAVOCYTOCHROME P450 BM3 | CYTOCHROME P450, FATTY ACID HYDROXYLASE, OXIDOREDUCTASE
1yqo:B (PRO25) to (ASP63) T268A MUTANT HEME DOMAIN OF FLAVOCYTOCHROME P450 BM3 | CYTOCHROME P450, FATTY ACID HYDROXYLASE, OXIDOREDUCTASE
1yqp:A (PRO25) to (ASP63) T268N MUTANT CYTOCHROME DOMAIN OF FLAVOCYTOCHROME P450 BM3 | CYTOCHROME P450, FATTY ACID HYDROXYLASE, OXIDOREDUCTASE
1yqp:B (PRO25) to (ASP63) T268N MUTANT CYTOCHROME DOMAIN OF FLAVOCYTOCHROME P450 BM3 | CYTOCHROME P450, FATTY ACID HYDROXYLASE, OXIDOREDUCTASE
1n6b:A (ILE50) to (GLY91) MICROSOMAL CYTOCHROME P450 2C5/3LVDH COMPLEX WITH A DIMETHYL DERIVATIVE OF SULFAPHENAZOLE | MEMBRANE PROTEIN, PROGESTERONE 21-HYDROXYLASE, BENZO(A), PYRENE HYDROXYLASE, ESTRADIOL 2-HYDROXYLASE, P450, CYP2C5, DIMETHYLSULFAPHENAZOLE COMPLEX, OXIDOREDUCTASE
1z10:A (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH COUMARIN BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE, HEME
1z10:B (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH COUMARIN BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE, HEME
1z10:C (GLN53) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH COUMARIN BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE, HEME
1z10:D (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH COUMARIN BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE, HEME
1z11:A (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH METHOXSALEN BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE, HEME, METHOXSALEN
1z11:B (GLN53) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH METHOXSALEN BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE, HEME, METHOXSALEN
1z11:C (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH METHOXSALEN BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE, HEME, METHOXSALEN
1z11:D (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH METHOXSALEN BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE, HEME, METHOXSALEN
5dnc:C (LYS48) to (HIS103) CRYSTAL STRUCTURE OF THE ASN-BOUND GUINEA PIG L-ASPARAGINASE 1 CATALYTIC DOMAIN ACTIVE SITE MUTANT T19A | ASPARAGINASE, HYDROLASE
3lc4:A (ILE53) to (TYR93) HUMAN CYTOCHROME P450 2E1 IN COMPLEX WITH OMEGA-IMIDAZOLYL-DODECANOIC ACID | CYP2E1, P450 2E1, MONOOXYGENASE, ACETAMINOPHEN, HEME, ENDOPLASMIC RETICULUM, IRON, MEMBRANE, METAL-BINDING, MICROSOME, OXIDOREDUCTASE
5dqn:A (PRO23) to (SER69) POLYETHYLENE 600-BOUND FORM OF P450 CYP125A3 MUTANT FROM MYOBACTERIUM SMEGMATIS - W83Y | OXIDOREDUCTASE, CHOLESTEROL METABOLISM
1zo4:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF A328S MUTANT OF THE HEME DOMAIN OF P450BM-3 | CYTOCHROME P-450, HEMEPROTEIN A328S, OXIDOREDUCTASE
1zo4:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF A328S MUTANT OF THE HEME DOMAIN OF P450BM-3 | CYTOCHROME P-450, HEMEPROTEIN A328S, OXIDOREDUCTASE
1zo9:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE WILD TYPE HEME DOMAIN OF P450BM-3 WITH N- PALMITOYLMETHIONINE | CYTOCHROME P-450, WILD TYPE HEME PROTEIN, OXIDOREDUCTASE
1zo9:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE WILD TYPE HEME DOMAIN OF P450BM-3 WITH N- PALMITOYLMETHIONINE | CYTOCHROME P-450, WILD TYPE HEME PROTEIN, OXIDOREDUCTASE
1zoa:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF A328V MUTANT OF THE HEME DOMAIN OF P450BM-3 WITH N-PALMITOYLGLYCINE | CYTOCHROME P-450, HEMEPROTEIN A328V, OXIDOREDUCTASE
1zoa:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF A328V MUTANT OF THE HEME DOMAIN OF P450BM-3 WITH N-PALMITOYLGLYCINE | CYTOCHROME P-450, HEMEPROTEIN A328V, OXIDOREDUCTASE
5e58:A (LEU52) to (ALA92) CRYSTAL STRUCTURE OF CYTOCHROME P450 2B35 FROM DESERT WOODRAT NEOTOMA LEPIDA IN COMPLEX WITH 4-(4-CHLOROPHENYL)IMIDAZOLE | CYTOCHROME P450; CYP2B35; NEOTOMA LEPIDA; WOODRAT, OXIDOREDUCTASE
5e58:B (LEU52) to (ALA92) CRYSTAL STRUCTURE OF CYTOCHROME P450 2B35 FROM DESERT WOODRAT NEOTOMA LEPIDA IN COMPLEX WITH 4-(4-CHLOROPHENYL)IMIDAZOLE | CYTOCHROME P450; CYP2B35; NEOTOMA LEPIDA; WOODRAT, OXIDOREDUCTASE
5e58:C (LEU52) to (ALA92) CRYSTAL STRUCTURE OF CYTOCHROME P450 2B35 FROM DESERT WOODRAT NEOTOMA LEPIDA IN COMPLEX WITH 4-(4-CHLOROPHENYL)IMIDAZOLE | CYTOCHROME P450; CYP2B35; NEOTOMA LEPIDA; WOODRAT, OXIDOREDUCTASE
5e58:E (LEU52) to (ALA92) CRYSTAL STRUCTURE OF CYTOCHROME P450 2B35 FROM DESERT WOODRAT NEOTOMA LEPIDA IN COMPLEX WITH 4-(4-CHLOROPHENYL)IMIDAZOLE | CYTOCHROME P450; CYP2B35; NEOTOMA LEPIDA; WOODRAT, OXIDOREDUCTASE
5e78:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF P450 BM3 HEME DOMAIN VARIANT COMPLEXED WITH CO(III)SEP | BM3, P450, MEDIATED ELECTRON TRANSPORT, CO(III)SEP, OXIDOREDUCTASE
5e78:B (PRO25) to (CYS62) CRYSTAL STRUCTURE OF P450 BM3 HEME DOMAIN VARIANT COMPLEXED WITH CO(III)SEP | BM3, P450, MEDIATED ELECTRON TRANSPORT, CO(III)SEP, OXIDOREDUCTASE
3awi:D (ALA121) to (LEU164) BIFUNCTIONAL TRNA MODIFICATION ENZYME MNMC FROM ESCHERICHIA COLI | TRNA MODIFICATION, ROSSMANN FOLD, OXIDOREDUCTASE, RNA BINDING, TRANSFERASE
5e9z:A (PRO25) to (ASP63) CYTOCHROME P450 BM3 MUTANT M11 | METABOLISM, MOLECULAR DYNAMICS, FREE ENERGY CALCULATIONS, THERMODYNAMIC INTEGRATION, OXIDOREDUCTASE
5e9z:B (PRO25) to (ASP63) CYTOCHROME P450 BM3 MUTANT M11 | METABOLISM, MOLECULAR DYNAMICS, FREE ENERGY CALCULATIONS, THERMODYNAMIC INTEGRATION, OXIDOREDUCTASE
5e9z:C (PRO25) to (ASP63) CYTOCHROME P450 BM3 MUTANT M11 | METABOLISM, MOLECULAR DYNAMICS, FREE ENERGY CALCULATIONS, THERMODYNAMIC INTEGRATION, OXIDOREDUCTASE
5e9z:D (PRO25) to (ASP63) CYTOCHROME P450 BM3 MUTANT M11 | METABOLISM, MOLECULAR DYNAMICS, FREE ENERGY CALCULATIONS, THERMODYNAMIC INTEGRATION, OXIDOREDUCTASE
5eae:A (PRO76) to (VAL112) SACCHAROMYCES CEREVISIAE CYP51 COMPLEXED WITH THE PLANT PATHOGEN INHIBITOR R-DESTHIO-PROTHIOCONAZOLE | CYP51, R-DESTHIO-PROTHIOCONAZOLE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX
5eag:A (PRO76) to (VAL112) SACCHAROMYCES CEREVISIAE CYP51 COMPLEXED WITH THE PLANT PATHOGEN INHIBITOR PROCHLORAZ | CYP51, PROCHLORAZ, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX
3m4v:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE A330P MUTANT OF CYTOCHROME P450 BM3 | CYTOCHROME P450 FOLD, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE
3m4v:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE A330P MUTANT OF CYTOCHROME P450 BM3 | CYTOCHROME P450 FOLD, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE
3b0h:B (ILE414) to (LEU438) ASSIMILATORY NITRITE REDUCTASE (NII4) FROM TOBBACO ROOT | SIROHEME, FE4S4 BINDING PROTEIN, OXIDOREDUCTASE
3b6h:A (ALA51) to (GLU89) CRYSTAL STRUCTURE OF HUMAN PROSTACYCLIN SYNTHASE IN COMPLEX WITH INHIBITOR MINOXIDIL | PROSTACYCLIN SYNTHASE, ENZYME-INHIBITOR COMPLEX, CYP8A1, CYTOCHROME P450, ENDOPLASMIC RETICULUM, FATTY ACID BIOSYNTHESIS, HEME, IRON, ISOMERASE, LIPID SYNTHESIS, MEMBRANE, METAL-BINDING, POLYMORPHISM, PROSTAGLANDIN BIOSYNTHESIS, TRANSMEMBRANE
3b6h:B (ALA51) to (GLU89) CRYSTAL STRUCTURE OF HUMAN PROSTACYCLIN SYNTHASE IN COMPLEX WITH INHIBITOR MINOXIDIL | PROSTACYCLIN SYNTHASE, ENZYME-INHIBITOR COMPLEX, CYP8A1, CYTOCHROME P450, ENDOPLASMIC RETICULUM, FATTY ACID BIOSYNTHESIS, HEME, IRON, ISOMERASE, LIPID SYNTHESIS, MEMBRANE, METAL-BINDING, POLYMORPHISM, PROSTAGLANDIN BIOSYNTHESIS, TRANSMEMBRANE
3b99:A (PHE52) to (TYR82) CRYSTAL STRUCTURE OF ZEBRAFISH PROSTACYCLIN SYNTHASE (CYTOCHROME P450 8A1) IN COMPLEX WITH SUBSTRATE ANALOG U51605 | PROSTACYCLIN SYNTHASE, CYTOCHROME P450 8A1, CYP8A1, SUBSTRATE ANALOG- ENZYME COMPLEX, ISOMERASE
3b99:B (ASP48) to (TYR82) CRYSTAL STRUCTURE OF ZEBRAFISH PROSTACYCLIN SYNTHASE (CYTOCHROME P450 8A1) IN COMPLEX WITH SUBSTRATE ANALOG U51605 | PROSTACYCLIN SYNTHASE, CYTOCHROME P450 8A1, CYP8A1, SUBSTRATE ANALOG- ENZYME COMPLEX, ISOMERASE
3b98:A (PHE52) to (SER87) CRYSTAL STRUCTURE OF ZEBRAFISH PROSTACYCLIN SYNTHASE (CYTOCHROME P450 8A1) | PROSTACYCLIN SYNTHASE, CYTOCHROME P450 8A1, CYP8A1, ISOMERASE
3b98:B (PHE52) to (SER87) CRYSTAL STRUCTURE OF ZEBRAFISH PROSTACYCLIN SYNTHASE (CYTOCHROME P450 8A1) | PROSTACYCLIN SYNTHASE, CYTOCHROME P450 8A1, CYP8A1, ISOMERASE
5em4:B (GLY50) to (ALA92) STRUCTURE OF CYP2B4 F244W IN A LIGAND FREE CONFORMATION | CYTOCHROME P450, MONOOXYGENASE, OXIDOREDUCTASE
3ben:A (PRO25) to (ASP63) STRUCTURE OF N-(12-IMIDAZOLYL-DODECANOYL)-L-LEUCINE INHIBITOR BOUND TO THE HEME DOMAIN OF CYTOCHROME P450-BM3 | PROTEIN-SUBSTRATE COMPLEX, HEMEPROTEIN, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, IRON, MEMBRANE, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3ben:B (PRO25) to (ASP63) STRUCTURE OF N-(12-IMIDAZOLYL-DODECANOYL)-L-LEUCINE INHIBITOR BOUND TO THE HEME DOMAIN OF CYTOCHROME P450-BM3 | PROTEIN-SUBSTRATE COMPLEX, HEMEPROTEIN, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, IRON, MEMBRANE, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
5eqb:A (PRO76) to (VAL112) CRYSTAL STRUCTURE OF LANOSTEROL 14-ALPHA DEMETHYLASE WITH INTACT TRANSMEMBRANE DOMAIN BOUND TO ITRACONAZOLE | STEROL ANTIFUNGAL MEMBRANE CYTOCHROME, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, CENTER FOR STRUCTURES OF MEMBRANE PROTEINS, CSMP, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4bf4:A (TYR29) to (LEU65) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
4bf4:B (TYR29) to (ASP67) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
4bf4:G (TYR29) to (ALA66) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
4bf4:L (TYR29) to (ASP67) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
5esl:A (LYS75) to (VAL112) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) T322I MUTANT COMPLEXED WITH ITRACONAZOLE | CYP51, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4bjk:A (LEU53) to (PHE90) CYP51 OF TRYPANOSOMA BRUCEI BOUND TO (S)-N-(3-(1H-INDOL-3- YL)-1-OXO-1-(PYRIDIN-4-YLAMINO)PROPAN-2-YL)-3,3'-DIFLUORO-( 1,1'-BIPHENYL)-4-CARBOXAMIDE | OXIDOREDUCTASE, ERGOSTEROL BIOSYNTHESIS
4bjk:B (LEU53) to (PHE90) CYP51 OF TRYPANOSOMA BRUCEI BOUND TO (S)-N-(3-(1H-INDOL-3- YL)-1-OXO-1-(PYRIDIN-4-YLAMINO)PROPAN-2-YL)-3,3'-DIFLUORO-( 1,1'-BIPHENYL)-4-CARBOXAMIDE | OXIDOREDUCTASE, ERGOSTEROL BIOSYNTHESIS
4bjk:D (SER51) to (PHE90) CYP51 OF TRYPANOSOMA BRUCEI BOUND TO (S)-N-(3-(1H-INDOL-3- YL)-1-OXO-1-(PYRIDIN-4-YLAMINO)PROPAN-2-YL)-3,3'-DIFLUORO-( 1,1'-BIPHENYL)-4-CARBOXAMIDE | OXIDOREDUCTASE, ERGOSTEROL BIOSYNTHESIS
4bmm:C (ASN51) to (PHE90) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- YLAMINO)PROPAN-2-YL)- 2',3,5'-TRIFLUORO-(1,1'-BIPHENYL)-4-CARBOXAMIDE | OXIDOREDUCTASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
4bmm:D (LEU53) to (PHE90) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- YLAMINO)PROPAN-2-YL)- 2',3,5'-TRIFLUORO-(1,1'-BIPHENYL)-4-CARBOXAMIDE | OXIDOREDUCTASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
3mzs:A (ARG35) to (GLU76) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP11A1 IN COMPLEX WITH 22- HYDROXY-CHOLESTEROL | CYP11A1, CYTOCHROME P450, MONOOXYGENASE, SIDE CHAIN CLEAVAGE ENZYME, CHOLESTEROL, CHOLESTEROL 20-22-DESMOLASE, STEROID METABOLISM, OXIDOREDUCTASE, HEME
3mzs:B (ARG35) to (GLU76) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP11A1 IN COMPLEX WITH 22- HYDROXY-CHOLESTEROL | CYP11A1, CYTOCHROME P450, MONOOXYGENASE, SIDE CHAIN CLEAVAGE ENZYME, CHOLESTEROL, CHOLESTEROL 20-22-DESMOLASE, STEROID METABOLISM, OXIDOREDUCTASE, HEME
3mzs:C (ARG35) to (GLU76) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP11A1 IN COMPLEX WITH 22- HYDROXY-CHOLESTEROL | CYP11A1, CYTOCHROME P450, MONOOXYGENASE, SIDE CHAIN CLEAVAGE ENZYME, CHOLESTEROL, CHOLESTEROL 20-22-DESMOLASE, STEROID METABOLISM, OXIDOREDUCTASE, HEME
3mzs:D (ARG35) to (GLU76) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP11A1 IN COMPLEX WITH 22- HYDROXY-CHOLESTEROL | CYP11A1, CYTOCHROME P450, MONOOXYGENASE, SIDE CHAIN CLEAVAGE ENZYME, CHOLESTEROL, CHOLESTEROL 20-22-DESMOLASE, STEROID METABOLISM, OXIDOREDUCTASE, HEME
4by0:A (ASN51) to (PHE90) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- YLAMINO)PROPAN-2-YL)-3,3'-DIFLUORO-(1,1'-BIPHENYL)-4- CARBOXAMIDE | OXIDOREDUCTASE, STEROL 14-DEMETHYLASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
3c6g:A (PRO62) to (SER103) CRYSTAL STRUCTURE OF CYP2R1 IN COMPLEX WITH VITAMIN D3 | CYTOCHROME P450, VITAMIN D3, VITAMIN D 25-HYDROXYLASE, DRUG METABOLISM, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, DISEASE MUTATION, ENDOPLASMIC RETICULUM, HEME, IRON, MEMBRANE, METAL-BINDING, MICROSOME, MONOOXYGENASE, OXIDOREDUCTASE
3c6g:B (PRO62) to (SER103) CRYSTAL STRUCTURE OF CYP2R1 IN COMPLEX WITH VITAMIN D3 | CYTOCHROME P450, VITAMIN D3, VITAMIN D 25-HYDROXYLASE, DRUG METABOLISM, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, DISEASE MUTATION, ENDOPLASMIC RETICULUM, HEME, IRON, MEMBRANE, METAL-BINDING, MICROSOME, MONOOXYGENASE, OXIDOREDUCTASE
3n9y:A (VAL35) to (GLU75) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH CHOLESTEROL | CYTOCHROME P450, CHOLESTEROL SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3n9y:B (VAL35) to (GLU75) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH CHOLESTEROL | CYTOCHROME P450, CHOLESTEROL SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3n9z:A (VAL35) to (GLU75) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH 22- HYDROXYCHOLESTEROL | CYTOCHROME P450, 22-HYDROXYCHOLESTEROL, CHOLESTEROL SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3n9z:B (VAL35) to (GLU75) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH 22- HYDROXYCHOLESTEROL | CYTOCHROME P450, 22-HYDROXYCHOLESTEROL, CHOLESTEROL SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3na0:A (VAL74) to (GLU114) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH 20,22- DIHYDROXYCHOLESTEROL | CYTOCHROME P450, 20,22-DIHYDROXYCHOLESTEROL, SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3na0:B (VAL74) to (GLU114) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH 20,22- DIHYDROXYCHOLESTEROL | CYTOCHROME P450, 20,22-DIHYDROXYCHOLESTEROL, SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3na1:A (VAL35) to (GLU75) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH 20- HYDROXYCHOLESTEROL | CYTOCHROME P450, 20-HYDROXYCHOLESTEROL, CHOLESTEROL SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3na1:B (LYS34) to (GLU75) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH 20- HYDROXYCHOLESTEROL | CYTOCHROME P450, 20-HYDROXYCHOLESTEROL, CHOLESTEROL SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
3cbd:A (PRO25) to (ASP63) DIRECTED EVOLUTION OF CYTOCHROME P450 BM3, TO OCTANE MONOXYGENASE 139-3 | CYTOCHROME P450, HEMEPROTEIN 139-3, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, IRON, MEMBRANE, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3cbd:B (PRO25) to (ASP63) DIRECTED EVOLUTION OF CYTOCHROME P450 BM3, TO OCTANE MONOXYGENASE 139-3 | CYTOCHROME P450, HEMEPROTEIN 139-3, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, IRON, MEMBRANE, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
4c27:A (PHE55) to (PHE90) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- 4-YLAMINO)PROPAN-2-YL)-2-FLUORO-4-(4-(4-(TRIFLUOROMETHYL) PHENYL)PIPERAZIN-1-YL)BENZAMIDE | OXIDOREDUCTASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
3nc6:A (ASN18) to (LEU53) CYP134A1 1-PHENYLIMIDAZOLE BOUND STRUCTURE | CYTOCHROME P450 OXIDASE, HAEM PROTEIN, OXIDOREDUCTASE
4c3h:B (ILE457) to (ARG501) STRUCTURE OF 14-SUBUNIT RNA POLYMERASE I AT 3.27 A RESOLUTION, CRYSTAL FORM C2-93 | TRANSCRIPTION
4c3i:B (ILE457) to (ARG501) STRUCTURE OF 14-SUBUNIT RNA POLYMERASE I AT 3.0 A RESOLUTION, CRYSTAL FORM C2-100 | TRANSFERASE
4c3j:B (ILE457) to (ARG501) STRUCTURE OF 14-SUBUNIT RNA POLYMERASE I AT 3.35 A RESOLUTION, CRYSTAL FORM C2-90 | TRANSCRIPTION
3ngw:A (PRO98) to (GLY145) CRYSTAL STRUCTURE OF MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS PROTEIN A FROM ARCHAEOGLOBUS FULGIDUS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET GR189 | ALPHA-BETA PROTEIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, BIOSYNTHETIC PROTEIN
4rrt:A (LEU51) to (ALA92) CRYSTAL STRUCTURE OF A HUMAN CYTOCHROME P450 2B6 (Y226H/K262R) IN COMPLEX WITH (+)-3-CARENE | P450, CYTOCHROME P450 2B6, MONOOXYGENASE, MEMBRANE PROTEIN, CYP2B6, ENDOPLASMIC RETICULUM, HEME, IRON, METAL BINDING, MICROSOME, OXIDOREDUCTASE
4rrt:B (LEU51) to (ALA92) CRYSTAL STRUCTURE OF A HUMAN CYTOCHROME P450 2B6 (Y226H/K262R) IN COMPLEX WITH (+)-3-CARENE | P450, CYTOCHROME P450 2B6, MONOOXYGENASE, MEMBRANE PROTEIN, CYP2B6, ENDOPLASMIC RETICULUM, HEME, IRON, METAL BINDING, MICROSOME, OXIDOREDUCTASE
4rsn:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE E267V MUTANT OF CYTOCHROME P450 BM3 | BIFUNCTIONAL P-450/NADPH-P450 REDUCTASE, HEME DOMAIN, OXIDOREDUCTASE
4rsn:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE E267V MUTANT OF CYTOCHROME P450 BM3 | BIFUNCTIONAL P-450/NADPH-P450 REDUCTASE, HEME DOMAIN, OXIDOREDUCTASE
4rui:A (MET54) to (ALA95) CRYSTAL STRUCTURE OF A CYTOCHROME P450 2A6 IN COMPLEX WITH A MONOTERPENE - SABINENE. | P450, CYTOCHROME P450 2A6, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP2A6, ENDOPLASMIC RETICULUM, HEME, IRON, MEMBRANE, METAL BINDING, MICROSOME
4rui:B (GLN53) to (ALA95) CRYSTAL STRUCTURE OF A CYTOCHROME P450 2A6 IN COMPLEX WITH A MONOTERPENE - SABINENE. | P450, CYTOCHROME P450 2A6, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP2A6, ENDOPLASMIC RETICULUM, HEME, IRON, MEMBRANE, METAL BINDING, MICROSOME
4rui:C (GLN53) to (ALA95) CRYSTAL STRUCTURE OF A CYTOCHROME P450 2A6 IN COMPLEX WITH A MONOTERPENE - SABINENE. | P450, CYTOCHROME P450 2A6, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP2A6, ENDOPLASMIC RETICULUM, HEME, IRON, MEMBRANE, METAL BINDING, MICROSOME
4rui:E (GLN53) to (ALA95) CRYSTAL STRUCTURE OF A CYTOCHROME P450 2A6 IN COMPLEX WITH A MONOTERPENE - SABINENE. | P450, CYTOCHROME P450 2A6, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP2A6, ENDOPLASMIC RETICULUM, HEME, IRON, MEMBRANE, METAL BINDING, MICROSOME
3o0p:A (SER127) to (LYS171) PILUS-RELATED SORTASE C OF GROUP B STREPTOCOCCUS | SORTASE, PILI ASSEMBLY, PILI SUBUNITS, TRANSFERASE ,HYDROLASE, TRANSFERASE, HYDROLASE
3czh:A (HIS63) to (SER103) CRYSTAL STRUCTURE OF CYP2R1 IN COMPLEX WITH VITAMIN D2 | CYTOCHROME P450, VITAMIN D, VITAMIN S 25-HYDROXYLASE, DRUG METABOLISM, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, DISEASE MUTATION, ENDOPLASMIC RETICULUM, HEME, IRON, MEMBRANE, METAL-BINDING, MICROSOME, MONOOXYGENASE, OXIDOREDUCTASE
3czh:B (PRO62) to (SER103) CRYSTAL STRUCTURE OF CYP2R1 IN COMPLEX WITH VITAMIN D2 | CYTOCHROME P450, VITAMIN D, VITAMIN S 25-HYDROXYLASE, DRUG METABOLISM, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, DISEASE MUTATION, ENDOPLASMIC RETICULUM, HEME, IRON, MEMBRANE, METAL-BINDING, MICROSOME, MONOOXYGENASE, OXIDOREDUCTASE
3dbg:A (ASP43) to (ASN82) CRYSTAL STRUCTURE OF CYTOCHROME P450 170A1 (CYP170A1) FROM STREPTOMYCES COELICOLOR | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP170A1, MOLECULAR MECHANISM, HEME, IRON, METAL-BINDING, MONOOXYGENASE
3dbg:B (ASP43) to (ASN82) CRYSTAL STRUCTURE OF CYTOCHROME P450 170A1 (CYP170A1) FROM STREPTOMYCES COELICOLOR | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP170A1, MOLECULAR MECHANISM, HEME, IRON, METAL-BINDING, MONOOXYGENASE
5ghr:A (VAL373) to (GLY419) DNA REPLICATION PROTEIN | DNA REPLICATION, DNA BINDING PROTEIN-REPLICATION COMPLEX
3dgi:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF F87A/T268A MUTANT OF CYP BM3 | CYTOCHROME P450, BM3, DMSO, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3dgi:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF F87A/T268A MUTANT OF CYP BM3 | CYTOCHROME P450, BM3, DMSO, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3dl9:A (HIS63) to (SER103) CRYSTAL STRUCTURE OF CYP2R1 IN COMPLEX WITH 1-ALPHA-HYDROXY- VITAMIN D2 | CYTOCHROME P450, VITAMIN D, VITAMIN S 25-HYDROXYLASE, DRUG METABOLISM, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, DISEASE MUTATION, ENDOPLASMIC RETICULUM, HEME, IRON, MEMBRANE, METAL-BINDING, MICROSOME, MONOOXYGENASE, OXIDOREDUCTASE
3dl9:B (PRO62) to (SER103) CRYSTAL STRUCTURE OF CYP2R1 IN COMPLEX WITH 1-ALPHA-HYDROXY- VITAMIN D2 | CYTOCHROME P450, VITAMIN D, VITAMIN S 25-HYDROXYLASE, DRUG METABOLISM, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, DISEASE MUTATION, ENDOPLASMIC RETICULUM, HEME, IRON, MEMBRANE, METAL-BINDING, MICROSOME, MONOOXYGENASE, OXIDOREDUCTASE
4d75:A (CYS58) to (VAL93) CYTOCHROME P450 3A4 BOUND TO AN INHIBITOR | OXIDOREDUCTASE, MONOOXYGENASE, INHIBITORY COMPLEX
4d78:A (PHE57) to (VAL93) CYTOCHROME P450 3A4 BOUND TO AN INHIBITOR | OXIDOREDUCTASE, MONOOXYGENASE, HUMAN CYP3A4, INHIBITORY COMPLEX
4d7d:A (PHE57) to (CYS98) CYTOCHROME P450 3A4 BOUND TO AN INHIBITOR | OXIDOREDUCTASE, MONOOXYGENASE, HUMAN CYP3A4, INHIBITORY COMPLEX
4dls:A (GLY15) to (TYR64) H-RAS SET 1 CACL2 'MIXED' | GTP-BINDING, NUCLEOTIDE BINDING, SIGNALING PROTEIN
3p99:D (SER51) to (PHE90) STEROL 14ALPHA-DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH DELTA7-14ALPHA-METHYLENE-CYCLOPROPYL-DIHYDROLANOSTEROL | CYTOCHROME P450 FOLD/STEROL 14-ALPHA DEMETHYLASE, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, HEMOPROTEIN, STEROL BIOSYNTHESIS, CYTOCHROME P450 REDUCTASE (CPR), ENDOPLASMIC RETICULUM, MEMBRANE
5hs1:A (PRO76) to (VAL112) SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) COMPLEXED WITH VORICONAZOLE | VORICONAZOLE, CYP51, OXIDOREDUCTASE-OXIDOREDUCATSE INHIBITOR COMPLEX, RESISTANCE MUTATION, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3e4e:B (ILE53) to (TYR93) HUMAN CYTOCHROME P450 2E1 IN COMPLEX WITH THE INHIBITOR 4- METHYLPYRAZOLE | CYP2E1, P450 2E1, MONOOXYGENASE, ACETAMINOPHEN, OXIDOREDUCTASE, HEME, ENDOPLASMIC RETICULUM, IRON, MEMBRANE, METAL-BINDING, MICROSOME
4dtw:B (PRO25) to (ASP63) CYTOCHROME P450 BM3H-8C8 MRI SENSOR BOUND TO SEROTONIN | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4dtw:A (PRO25) to (ASP63) CYTOCHROME P450 BM3H-8C8 MRI SENSOR BOUND TO SEROTONIN | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4dty:B (PRO25) to (ASP63) CYTOCHROME P450 BM3H-8C8 MRI SENSOR, NO LIGAND | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4dty:A (PRO25) to (ASP63) CYTOCHROME P450 BM3H-8C8 MRI SENSOR, NO LIGAND | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4dtz:A (PRO25) to (ASP63) CYTOCHROME P450 BM3H-8C8 MRI SENSOR BOUND TO DOPAMINE | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4dtz:B (PRO25) to (ASP63) CYTOCHROME P450 BM3H-8C8 MRI SENSOR BOUND TO DOPAMINE | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4du2:B (PRO25) to (ASP63) CYTOCHROME P450 BM3H-B7 MRI SENSOR BOUND TO DOPAMINE | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4du2:A (PRO25) to (ASP63) CYTOCHROME P450 BM3H-B7 MRI SENSOR BOUND TO DOPAMINE | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4duf:A (PRO25) to (ASP63) CYTOCHROME P450 BM3H-2G9 MRI SENSOR BOUND TO SEROTONIN | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4duf:B (PRO25) to (ASP63) CYTOCHROME P450 BM3H-2G9 MRI SENSOR BOUND TO SEROTONIN | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4duf:C (PRO25) to (ASP63) CYTOCHROME P450 BM3H-2G9 MRI SENSOR BOUND TO SEROTONIN | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4duf:D (PRO25) to (CYS62) CYTOCHROME P450 BM3H-2G9 MRI SENSOR BOUND TO SEROTONIN | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4dua:A (PRO25) to (ASP63) CYTOCHROME P450 BM3H-9D7 MRI SENSOR, NO LIGAND | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4dua:B (PRO25) to (CYS62) CYTOCHROME P450 BM3H-9D7 MRI SENSOR, NO LIGAND | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4dub:A (PRO25) to (ASP63) CYTOCHROME P450 BM3H-9D7 MRI SENSOR BOUND TO DOPAMINE | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4dub:B (PRO25) to (ASP63) CYTOCHROME P450 BM3H-9D7 MRI SENSOR BOUND TO DOPAMINE | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4dud:A (PRO25) to (ASP63) CYTOCHROME P450 BM3H-2G9C6 MRI SENSOR, NO LIGAND | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4dud:B (PRO25) to (ASP63) CYTOCHROME P450 BM3H-2G9C6 MRI SENSOR, NO LIGAND | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4due:A (PRO25) to (ASP63) CYTOCHROME P450 BM3H-2G9C6 MRI SENSOR BOUND TO SEROTONIN | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4due:B (PRO25) to (ASP63) CYTOCHROME P450 BM3H-2G9C6 MRI SENSOR BOUND TO SEROTONIN | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4uhl:B (SER80) to (SER120) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhl:D (SER80) to (SER120) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4dvq:A (HIS63) to (ASP104) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, CORTICOSTEROID, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE
4dvq:B (HIS63) to (ASP104) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, CORTICOSTEROID, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE
4dvq:G (HIS63) to (ASP104) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, CORTICOSTEROID, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE
4dvq:J (LEU64) to (ASP104) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, CORTICOSTEROID, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE
4dvq:K (HIS63) to (ASP104) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, CORTICOSTEROID, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE
4dvq:L (LEU64) to (ASP104) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, CORTICOSTEROID, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE
3pm0:A (ALA70) to (GLY111) STRUCTURAL CHARACTERIZATION OF THE COMPLEX BETWEEN ALPHA- NAPHTHOFLAVONE AND HUMAN CYTOCHROME P450 1B1 (CYP1B1) | CYP1B1, P450 1B1, P450, MONOOXYGENASE, ALPHA-NAPHTHOFLAVONE, HEME, 17BETA-ESTRADIOL, OXIDOREDUCTASE
3psx:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE KT2 MUTANT OF CYTOCHROME P450 BM3 | CYTOCHROME P450 FOLD, OXIDOREDUCTASE
3psx:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE KT2 MUTANT OF CYTOCHROME P450 BM3 | CYTOCHROME P450 FOLD, OXIDOREDUCTASE
4ejg:A (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH NICOTINE | CYP2A13, CYTOCHROME P450 2A13, HEME PROTEIN, P450 2A13, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejg:B (GLN53) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH NICOTINE | CYP2A13, CYTOCHROME P450 2A13, HEME PROTEIN, P450 2A13, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejg:C (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH NICOTINE | CYP2A13, CYTOCHROME P450 2A13, HEME PROTEIN, P450 2A13, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejg:D (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH NICOTINE | CYP2A13, CYTOCHROME P450 2A13, HEME PROTEIN, P450 2A13, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejg:E (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH NICOTINE | CYP2A13, CYTOCHROME P450 2A13, HEME PROTEIN, P450 2A13, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejg:F (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH NICOTINE | CYP2A13, CYTOCHROME P450 2A13, HEME PROTEIN, P450 2A13, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejg:G (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH NICOTINE | CYP2A13, CYTOCHROME P450 2A13, HEME PROTEIN, P450 2A13, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejg:H (GLN53) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH NICOTINE | CYP2A13, CYTOCHROME P450 2A13, HEME PROTEIN, P450 2A13, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejh:A (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH 4-(METHYLNITROSAMINO)-1-(3- PYRIDYL)-1-BUTANONE (NNK) | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejh:B (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH 4-(METHYLNITROSAMINO)-1-(3- PYRIDYL)-1-BUTANONE (NNK) | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejh:C (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH 4-(METHYLNITROSAMINO)-1-(3- PYRIDYL)-1-BUTANONE (NNK) | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejh:D (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH 4-(METHYLNITROSAMINO)-1-(3- PYRIDYL)-1-BUTANONE (NNK) | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejh:E (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH 4-(METHYLNITROSAMINO)-1-(3- PYRIDYL)-1-BUTANONE (NNK) | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejh:F (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH 4-(METHYLNITROSAMINO)-1-(3- PYRIDYL)-1-BUTANONE (NNK) | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejh:G (GLN53) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH 4-(METHYLNITROSAMINO)-1-(3- PYRIDYL)-1-BUTANONE (NNK) | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4eji:A (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH TWO MOLECULES OF 4- (METHYLNITROSAMINO)-1-(3-PURIDYL)-1-BUTANONE | CYP2A13, CYTOCHROME P450 2A13, P450 2A13, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejj:A (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A6 IN COMPLEX WITH NICOTINE | CYTOCHROME P450 2A6, P450 2A6, HEME PROTEIN, MONOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejj:C (GLN53) to (ALA95) HUMAN CYTOCHROME P450 2A6 IN COMPLEX WITH NICOTINE | CYTOCHROME P450 2A6, P450 2A6, HEME PROTEIN, MONOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3qm4:A (THR54) to (GLY95) HUMAN CYTOCHROME P450 (CYP) 2D6 - PRINOMASTAT COMPLEX | CYP2D6, P450 2D6, P450, MONOOXYGENASE, PRINOMASTAT, HEME, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3qm4:B (THR54) to (GLY95) HUMAN CYTOCHROME P450 (CYP) 2D6 - PRINOMASTAT COMPLEX | CYP2D6, P450 2D6, P450, MONOOXYGENASE, PRINOMASTAT, HEME, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4uyl:B (ASP71) to (GLY111) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51B) FROM A PATHOGENIC FILAMENTOUS FUNGUS ASPERGILLUS FUMIGATUS IN COMPLEX WITH VNI | CYTOCHROME P450, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4uym:B (TYR73) to (GLY111) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51B) FROM A PATHOGENIC FILAMENTOUS FUNGUS ASPERGILLUS FUMIGATUS IN COMPLEX WITH VORICONAZOLE | CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE,
4fdh:A (HIS63) to (ASP104) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH FADROZOLE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, INHIBITOR, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4fdh:E (HIS63) to (ASP104) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH FADROZOLE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, INHIBITOR, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4fdh:H (HIS63) to (ASP104) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH FADROZOLE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, INHIBITOR, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4fdh:I (HIS63) to (ASP104) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH FADROZOLE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, INHIBITOR, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4fdh:K (LEU64) to (ASP104) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH FADROZOLE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, INHIBITOR, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4fdh:L (HIS63) to (ASP104) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH FADROZOLE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, INHIBITOR, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3qz1:A (LEU45) to (TRP86) CRYSTAL STRUCTURE OF BOVINE STEROID OF 21-HYDROXYLASE (P450C21) | P450 MONOOXYGENASE, 21-HYDROXYLASE, OXIDOREDUCTASE
3qz1:B (LEU45) to (TRP86) CRYSTAL STRUCTURE OF BOVINE STEROID OF 21-HYDROXYLASE (P450C21) | P450 MONOOXYGENASE, 21-HYDROXYLASE, OXIDOREDUCTASE
3qz1:C (ASN44) to (TRP86) CRYSTAL STRUCTURE OF BOVINE STEROID OF 21-HYDROXYLASE (P450C21) | P450 MONOOXYGENASE, 21-HYDROXYLASE, OXIDOREDUCTASE
3qz1:D (LEU45) to (TRP86) CRYSTAL STRUCTURE OF BOVINE STEROID OF 21-HYDROXYLASE (P450C21) | P450 MONOOXYGENASE, 21-HYDROXYLASE, OXIDOREDUCTASE
4fia:A (GLN61) to (MET98) CRYSTAL STRUCTURE OF HUMAN CYP46A1 P450 WITH BICALUTAMIDE BOUND | CYTOCHROME P450, CYP46A1, BICALUTAMIDE COMPLEX, OXIDOREDUCTASE
3r1a:H (GLY50) to (ALA92) CLOSED CRYSTAL STRUCTURE OF CYTOCHROME P450 2B4 COVALENTLY BOUND TO THE MECHANISM-BASED INACTIVATOR TERT-BUTYLPHENYLACETYLENE | CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, T302 COVALENTLY LINKED TO TERT-BUTYLPHENYLACETYLENE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3r1b:B (ARG48) to (ALA92) OPEN CRYSTAL STRUCTURE OF CYTOCHROME P450 2B4 COVALENTLY BOUND TO THE MECHANISM-BASED INACTIVATOR TERT-BUTYLPHENYLACETYLENE | CYTOCHROME P450 2B4, MONOOXYGENASE, MEMBRANE PROTEIN, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
5jq2:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE RU(BPY)2PHENA FUNCTIONALIZED P450 BM3 L407C HEME DOMAIN MUTANT IN COMPLEX WITH N-PALMITOYLGLYCINE | HYBRID P450 BM3 ENZYMES, ELECTRON TRANSFER, PHOTOSENSITIZER, PHOTOCATALYTIC ACTIVITY, OXIDOREDUCTASE
5jq2:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE RU(BPY)2PHENA FUNCTIONALIZED P450 BM3 L407C HEME DOMAIN MUTANT IN COMPLEX WITH N-PALMITOYLGLYCINE | HYBRID P450 BM3 ENZYMES, ELECTRON TRANSFER, PHOTOSENSITIZER, PHOTOCATALYTIC ACTIVITY, OXIDOREDUCTASE
5jqu:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN G265F/T269V/L272W/L322I/F405M/A406S (WIVS-FM) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqu:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN G265F/T269V/L272W/L322I/F405M/A406S (WIVS-FM) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqu:C (PRO25) to (ASP63) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN G265F/T269V/L272W/L322I/F405M/A406S (WIVS-FM) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqu:D (VAL26) to (ASP63) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN G265F/T269V/L272W/L322I/F405M/A406S (WIVS-FM) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqu:E (PRO25) to (ASP63) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN G265F/T269V/L272W/L322I/F405M/A406S (WIVS-FM) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqu:F (LYS24) to (ALA61) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN G265F/T269V/L272W/L322I/F405M/A406S (WIVS-FM) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqu:G (LYS24) to (ASP63) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN G265F/T269V/L272W/L322I/F405M/A406S (WIVS-FM) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqu:H (PRO25) to (CYS62) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN G265F/T269V/L272W/L322I/F405M/A406S (WIVS-FM) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqv:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN T269V/L272W/L322I/A406S (WIVS) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqv:B (PRO25) to (CYS62) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN T269V/L272W/L322I/A406S (WIVS) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqv:D (PRO25) to (ASP63) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN T269V/L272W/L322I/A406S (WIVS) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqv:E (PRO25) to (ASP63) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN T269V/L272W/L322I/A406S (WIVS) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqv:G (PRO25) to (CYS62) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN T269V/L272W/L322I/A406S (WIVS) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqv:H (PRO25) to (ASP63) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN T269V/L272W/L322I/A406S (WIVS) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jtd:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE RU(BPY)2PHENA FUNCTIONALIZED P450 BM3 L407C HEME DOMAIN MUTANT IN COMPLEX WITH DMSO. | HYBRID P450 BM3 ENZYMES, ELECTRON TRANSFER, PHOTOSENSITIZER, PHOTOCATALYTIC ACTIVITY, OXIDOREDUCTASE
5jtd:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF THE RU(BPY)2PHENA FUNCTIONALIZED P450 BM3 L407C HEME DOMAIN MUTANT IN COMPLEX WITH DMSO. | HYBRID P450 BM3 ENZYMES, ELECTRON TRANSFER, PHOTOSENSITIZER, PHOTOCATALYTIC ACTIVITY, OXIDOREDUCTASE
4g3j:C (PHE55) to (PHE90) STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH THE VNI DERIVATIVE (R)-N-(1-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4- TRIAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)BENZAMIDE [R- VNI-TRIAZOLE (VNT)] | CYTOCHROME P450 FOLD, HEME, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANE BIOGENESIS, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4gl7:A (ILE70) to (MET107) STRUCTURE OF HUMAN PLACENTAL AROMATASE COMPLEXED WITH DESIGNED INHIBITOR HDDG046 (COMPOUND 5) | NOVEL AROMATASE INHIBITOR, OXIDOREDUCTASE, ESTROGEN SYNTHETASE, CYTOCHROME P450 REDUCTASE, ER MEMBRANE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
5kxf:A (ARG502) to (GLN547) CRYSTAL STRUCTURE OF THE SPOC DOMAIN OF THE ARABIDOPSIS FLOWERING REGULATOR FPA | SPOC DOMAIN ARABIDOPSIS FLOWERING REGULATOR, RNA BINDING PROTEIN
5l90:B (PHE26) to (LEU59) THE CRYSTAL STRUCTURE OF SUBSTRATE-FREE CYP109E1 FROM BACILLUS MEGATERIUM AT 2.55 ANGSTROM RESOLUTION | BACILLUS, BACTERIAL PROTEINS, BINDING SITES, CATALYSIS, CYTOCHROME P- 450 ENZYME SYSTEM, CYTOCHROME P450, HYDROXYLATION, ESCHERICHIA COLI, HEME, LIGANDS, MOLECULAR STRUCTURE, OXIDATION-REDUCTION, OXYGEN, PROTEIN, PROTEIN STRUCTURE, SECONDARY, STEROIDS, SUBSTRATE SPECIFICITY, OXIDOREDUCTASE
5l92:B (PHE26) to (LEU59) THE 2.1 A CRYSTAL STRUCTURE OF CYP109E1 FROM BACILLUS MEGATERIUM IN COMPLEX WITH CORTICOSTERONE | BACILLUS, BACTERIAL PROTEINS, BINDING SITES, CATALYSIS, CORTICOSTERONE, CYTOCHROME P-450 ENZYME SYSTEM, CYTOCHROME P450, HYDROXYLATION, ESCHERICHIA COLI, HEME, LIGANDS, MOLECULAR STRUCTURE, OXIDATION-REDUCTION, OXYGEN, PROTEIN, PROTEIN STRUCTURE, SECONDARY, STEROIDS, SUBSTRATE SPECIFICITY, OXIDOREDUCTASE
5l94:B (PHE26) to (LEU59) THE 2.25 A CRYSTAL STRUCTURE OF CYP109E1 FROM BACILLUS MEGATERIUM IN COMPLEX WITH TESTOSTERONE | BACILLUS, BACTERIAL PROTEINS, BINDING SITES, CATALYSIS, CYTOCHROME P- 450 ENZYME SYSTEM, CYTOCHROME P450, HYDROXYLATION, ESCHERICHIA COLI, HEME, LIGANDS, MOLECULAR STRUCTURE, OXIDATION-REDUCTION, OXYGEN, PROTEIN, PROTEIN STRUCTURE, SECONDARY, STEROIDS, SUBSTRATE SPECIFICITY, TESTOSTERONE, OXIDOREDUCTASE
1nr6:A (ILE50) to (GLY91) MICROSOMAL CYTOCHROME P450 2C5/3LVDH COMPLEX WITH DICLOFENAC | MEMBRANE PROTEIN, PROGESTERONE 21-HYDROXYLASE, BENZO(A), PYRENE HYDROXYLASE, ESTRADIOL 2-HYDROXYLASE, P450, CYP2C5, DICLOFENAC COMPLEX, OXIDOREDUCTASE
4hgf:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF P450 BM3 5F5K HEME DOMAIN VARIANT COMPLEXED WITH STYRENE | OXIDOREDUCTASE, P450 BM3, HEMOPROTEIN, STYRENE EPOXIDATION, INVERTED ENANTIOSELECTIVITY, HEME BINDING
4hgf:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF P450 BM3 5F5K HEME DOMAIN VARIANT COMPLEXED WITH STYRENE | OXIDOREDUCTASE, P450 BM3, HEMOPROTEIN, STYRENE EPOXIDATION, INVERTED ENANTIOSELECTIVITY, HEME BINDING
4hgh:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF P450 BM3 5F5 HEME DOMAIN VARIANT COMPLEXED WITH STYRENE (DATASET I) | OXIDOREDUCTASE, P450 BM3, HEMOPROTEIN, STYRENE EPOXIDATION, INVERTED ENANTIOSELECTIVITY, HEME BINDING
4hgh:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF P450 BM3 5F5 HEME DOMAIN VARIANT COMPLEXED WITH STYRENE (DATASET I) | OXIDOREDUCTASE, P450 BM3, HEMOPROTEIN, STYRENE EPOXIDATION, INVERTED ENANTIOSELECTIVITY, HEME BINDING
4hgi:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF P450 BM3 5F5 HEME DOMAIN VARIANT COMPLEXED WITH STYRENE (DATASET II) | OXIDOREDUCTASE, P450 BM3, HEMOPROTEIN, STYRENE EPOXIDATION, INVERTED ENANTIOSELECTIVITY, HEME BINDING
4hgi:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF P450 BM3 5F5 HEME DOMAIN VARIANT COMPLEXED WITH STYRENE (DATASET II) | OXIDOREDUCTASE, P450 BM3, HEMOPROTEIN, STYRENE EPOXIDATION, INVERTED ENANTIOSELECTIVITY, HEME BINDING
1bng:A (PHE7) to (GLY34) BARNASE S85C/H102C DISULFIDE MUTANT | ENDONUCLEASE
1bng:C (PHE7) to (GLY34) BARNASE S85C/H102C DISULFIDE MUTANT | ENDONUCLEASE
1brg:B (LEU7) to (GLY34) CRYSTALLOGRAPHIC ANALYSIS OF PHE->LEU SUBSTITUTION IN THE HYDROPHOBIC CORE OF BARNASE | ENDONUCLEASE
1brg:C (LEU7) to (GLY34) CRYSTALLOGRAPHIC ANALYSIS OF PHE->LEU SUBSTITUTION IN THE HYDROPHOBIC CORE OF BARNASE | ENDONUCLEASE
2pg6:A (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 L240C/N297Q | CYP2A6, P450 2A6, P450, MONOOXYGENASES, DRUG METABOLIZING ENZYME, HEME, INDOLE, MUTANT, OXIDOREDUCTASE
2pg6:B (MET54) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 L240C/N297Q | CYP2A6, P450 2A6, P450, MONOOXYGENASES, DRUG METABOLIZING ENZYME, HEME, INDOLE, MUTANT, OXIDOREDUCTASE
2pg6:D (GLN53) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 L240C/N297Q | CYP2A6, P450 2A6, P450, MONOOXYGENASES, DRUG METABOLIZING ENZYME, HEME, INDOLE, MUTANT, OXIDOREDUCTASE
2pg7:B (GLN53) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 N297Q/I300V | CYP2A6, P450 2A6, P450, MONOOXYGENASES, DRUG METABOLIZING ENZYME, HEME, INDOLE, MUTANT, OXIDOREDUCTASE
2pg7:C (GLN53) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 N297Q/I300V | CYP2A6, P450 2A6, P450, MONOOXYGENASES, DRUG METABOLIZING ENZYME, HEME, INDOLE, MUTANT, OXIDOREDUCTASE
2pg7:D (GLN53) to (ALA95) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 N297Q/I300V | CYP2A6, P450 2A6, P450, MONOOXYGENASES, DRUG METABOLIZING ENZYME, HEME, INDOLE, MUTANT, OXIDOREDUCTASE
2pvc:A (LYS292) to (SER352) DNMT3L RECOGNIZES UNMETHYLATED HISTONE H3 LYSINE 4 | DNMT3L, UNMETHYLATED H3K4, DE NOVO DNA METHYLATION, TRANSFERASE REGULATOR
2pvc:C (ASN291) to (SER353) DNMT3L RECOGNIZES UNMETHYLATED HISTONE H3 LYSINE 4 | DNMT3L, UNMETHYLATED H3K4, DE NOVO DNA METHYLATION, TRANSFERASE REGULATOR
2pwy:A (HIS36) to (HIS69) CRYSTAL STRUCTURE OF A M1A58 TRNA METHYLTRANSFERASE | MTASE, ADOMET, TRMI, TRNA-M1A58, TRANSFERASE
2pwy:B (HIS36) to (HIS69) CRYSTAL STRUCTURE OF A M1A58 TRNA METHYLTRANSFERASE | MTASE, ADOMET, TRMI, TRNA-M1A58, TRANSFERASE
2q6n:D (LEU51) to (GLN91) STRUCTURE OF CYTOCHROME P450 2B4 WITH BOUND 1-(4- CHOLOROPHENYL)IMIDAZOLE | P450, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2
2ca0:B (TYR29) to (ALA66) CRYSTAL STRUCTURE OF YC-17-BOUND CYTOCHROME P450 PIKC ( CYP107L1) | OXIDOREDUCTASE, CYTOCHROME P450, PIKC, YC-17, MACROLIDE MONOOXYGENASE, ANTIBIOTIC BIOSYNTHESIS, HEME, IRON, METAL-BINDING
3g66:A (SER129) to (LYS173) THE CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE SORTASE C PROVIDES NOVEL INSIGHTS INTO CATALYSIS AS WELL AS PILIN SUBSTRATE SPECIFICITY | SORTASE, PILUS, S. PNEUMONIAE, TRANSFERASE
3g66:B (SER129) to (LYS173) THE CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE SORTASE C PROVIDES NOVEL INSIGHTS INTO CATALYSIS AS WELL AS PILIN SUBSTRATE SPECIFICITY | SORTASE, PILUS, S. PNEUMONIAE, TRANSFERASE
3t3r:A (GLN53) to (ALA95) HUMAN CYTOCHROME P450 2A6 IN COMPLEX WITH PILOCARPINE | CYP2A6, CYTOCHROME P450 2A6, P450 2A6, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3r:B (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A6 IN COMPLEX WITH PILOCARPINE | CYP2A6, CYTOCHROME P450 2A6, P450 2A6, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3r:C (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A6 IN COMPLEX WITH PILOCARPINE | CYP2A6, CYTOCHROME P450 2A6, P450 2A6, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3t3r:D (MET54) to (ALA95) HUMAN CYTOCHROME P450 2A6 IN COMPLEX WITH PILOCARPINE | CYP2A6, CYTOCHROME P450 2A6, P450 2A6, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
1dt6:A (ILE50) to (GLY91) STRUCTURE OF MAMMALIAN CYTOCHROME P450 2C5 | MEMBRANE PROTEIN, PROGESTERONE 21-HYDROXYLASE, BENZO(A)PYRENE HYDROXYLASE, ESTRADIOL 2-HYDROXYLASE, P450, CYP2C5, OXIDOREDUCTASE
4j6d:A (LEU19) to (ASP57) THE 2.4 A CRYSTAL STRUCTURE OF CYP154C5 FROM NOCARDIA FARCINICA IN COMPLEX WITH TESTOSTERONE | CYTOCHROM P450, STEROID HYDROXYLATING MONOOXYGENASE, STEROID BINDING, OXIDOREDUCTASE-SUBSTRATE COMPLEX
4j6d:B (LEU19) to (ASP57) THE 2.4 A CRYSTAL STRUCTURE OF CYP154C5 FROM NOCARDIA FARCINICA IN COMPLEX WITH TESTOSTERONE | CYTOCHROM P450, STEROID HYDROXYLATING MONOOXYGENASE, STEROID BINDING, OXIDOREDUCTASE-SUBSTRATE COMPLEX
4y8w:A (LEU45) to (TRP86) CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 21A2 PROGESTERONE COMPLEX | STEROID HYDROXYLATION, MONOOXYGENASES, ADRENAL STEROIDOGENESIS, CONGENITAL ADRENAL HYPERPLASIA, ADDISON'S DISEASE, KINETIC ISOTOPE EFFECTS, OXIDOREDUCTASE
4y8w:B (ASP44) to (TRP86) CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 21A2 PROGESTERONE COMPLEX | STEROID HYDROXYLATION, MONOOXYGENASES, ADRENAL STEROIDOGENESIS, CONGENITAL ADRENAL HYPERPLASIA, ADDISON'S DISEASE, KINETIC ISOTOPE EFFECTS, OXIDOREDUCTASE
4y8w:C (ASP44) to (LYS85) CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 21A2 PROGESTERONE COMPLEX | STEROID HYDROXYLATION, MONOOXYGENASES, ADRENAL STEROIDOGENESIS, CONGENITAL ADRENAL HYPERPLASIA, ADDISON'S DISEASE, KINETIC ISOTOPE EFFECTS, OXIDOREDUCTASE
3tk3:A (LEU51) to (ALA92) CYTOCHROME P450 2B4 MUTANT L437A IN COMPLEX WITH 4-(4-CHLOROPHENYL) IMIDAZOLE | P450, CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2
3tk3:C (GLY50) to (ALA92) CYTOCHROME P450 2B4 MUTANT L437A IN COMPLEX WITH 4-(4-CHLOROPHENYL) IMIDAZOLE | P450, CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2
3tzo:A (ASP27) to (ASP66) THE ROLE OF I87 OF CYP158A2 IN OXIDATIVE COUPLING REACTION | CYP158A2, PHENOLIC COUPLING REACTION, P450, MONOOXYGENASE, OXIDOREDUCTASE
3tzo:B (PRO28) to (ASP66) THE ROLE OF I87 OF CYP158A2 IN OXIDATIVE COUPLING REACTION | CYP158A2, PHENOLIC COUPLING REACTION, P450, MONOOXYGENASE, OXIDOREDUCTASE
1fag:A (PRO25) to (CYS62) STRUCTURE OF CYTOCHROME P450 | MONOOXYGENASE, ELECTRON TRANSPORT, HEME
1fag:B (PRO25) to (CYS62) STRUCTURE OF CYTOCHROME P450 | MONOOXYGENASE, ELECTRON TRANSPORT, HEME
1fag:D (PRO25) to (CYS62) STRUCTURE OF CYTOCHROME P450 | MONOOXYGENASE, ELECTRON TRANSPORT, HEME
4k9w:A (PHE57) to (GLU97) COMPLEX OF HUMAN CYP3A4 WITH A DESOXYRITONAVIR ANALOG | CYTOCHROME P450 3A4, ALPHA-BETA PROTEIN, CYTOCHROME P450 FOLD, MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4k9w:B (PHE57) to (VAL93) COMPLEX OF HUMAN CYP3A4 WITH A DESOXYRITONAVIR ANALOG | CYTOCHROME P450 3A4, ALPHA-BETA PROTEIN, CYTOCHROME P450 FOLD, MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4k9w:D (PHE57) to (CYS98) COMPLEX OF HUMAN CYP3A4 WITH A DESOXYRITONAVIR ANALOG | CYTOCHROME P450 3A4, ALPHA-BETA PROTEIN, CYTOCHROME P450 FOLD, MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
2f5m:A (PHE5) to (GLY32) CROSS-LINKED BARNASE SOAKED IN BROMO-ETHANOL | DENATURATION, LYSOZYME, BARNASE, CROSS-LINKED CRYSTALS, GLUTARALDEHYDE, UREA, THIOUREA, BROMOETHANOL, HYDROLASE
2f5m:B (PHE5) to (GLY32) CROSS-LINKED BARNASE SOAKED IN BROMO-ETHANOL | DENATURATION, LYSOZYME, BARNASE, CROSS-LINKED CRYSTALS, GLUTARALDEHYDE, UREA, THIOUREA, BROMOETHANOL, HYDROLASE
2f5m:C (PHE5) to (GLY32) CROSS-LINKED BARNASE SOAKED IN BROMO-ETHANOL | DENATURATION, LYSOZYME, BARNASE, CROSS-LINKED CRYSTALS, GLUTARALDEHYDE, UREA, THIOUREA, BROMOETHANOL, HYDROLASE
2f5w:A (PHE5) to (GLY32) CROSS-LINKED BARNASE SOAKED IN 3 M THIOUREA | DENATURATION, LYSOZYME, BARNASE, CROSS-LINKED CRYSTALS, GLUTARALDEHYDE, UREA, THIOUREA, BROMOETHANOL, HYDROLASE
2f5w:B (PHE5) to (GLY32) CROSS-LINKED BARNASE SOAKED IN 3 M THIOUREA | DENATURATION, LYSOZYME, BARNASE, CROSS-LINKED CRYSTALS, GLUTARALDEHYDE, UREA, THIOUREA, BROMOETHANOL, HYDROLASE
2f5w:C (PHE5) to (GLY32) CROSS-LINKED BARNASE SOAKED IN 3 M THIOUREA | DENATURATION, LYSOZYME, BARNASE, CROSS-LINKED CRYSTALS, GLUTARALDEHYDE, UREA, THIOUREA, BROMOETHANOL, HYDROLASE
2fdy:A (TYR55) to (ALA95) MICROSOMAL P450 2A6 WITH THE INHIBITOR ADRITHIOL BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdy:C (MET54) to (ALA95) MICROSOMAL P450 2A6 WITH THE INHIBITOR ADRITHIOL BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdy:D (TYR55) to (ALA95) MICROSOMAL P450 2A6 WITH THE INHIBITOR ADRITHIOL BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
4zf6:A (PRO25) to (ASP63) CYTOCHROME P450 PENTAMUTANT FROM BM3 WITH BOUND PEG | CYTOCHROME P450, HEME OXIDASE DOMAIN, OXIDOREDUCTASE, BACILLUS MEGATERIUM
4kpb:A (PRO25) to (CYS62) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM-3 R47E MUTANT | HEME-DEPENDENT STEREOSPECIFIC OXIDATION OF SUBSTRATES, OXIDOREDUCTASE
4kpb:B (VAL26) to (ASP63) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM-3 R47E MUTANT | HEME-DEPENDENT STEREOSPECIFIC OXIDATION OF SUBSTRATES, OXIDOREDUCTASE
1gov:A (THR5) to (GLY33) RIBONUCLEASE BI(G SPECIFIC ENDONUCLEASE) COMPLEXED WITH SULFATE IONS | HYDROLASE, ENDORIBONUCLEASE, NUCLEASE
1smj:A (LYS24) to (CYS62) STRUCTURE OF THE A264E MUTANT OF CYTOCHROME P450 BM3 COMPLEXED WITH PALMITOLEATE | MONOOXYGENASE; FATTY ACID OXYGENASE; CYTOCHROME P450; SUBSTRATE BINDING; PALMITOLEATE, OXIDOREDUCTASE
1smj:C (PRO25) to (ASP63) STRUCTURE OF THE A264E MUTANT OF CYTOCHROME P450 BM3 COMPLEXED WITH PALMITOLEATE | MONOOXYGENASE; FATTY ACID OXYGENASE; CYTOCHROME P450; SUBSTRATE BINDING; PALMITOLEATE, OXIDOREDUCTASE
1smj:D (PRO25) to (ASP63) STRUCTURE OF THE A264E MUTANT OF CYTOCHROME P450 BM3 COMPLEXED WITH PALMITOLEATE | MONOOXYGENASE; FATTY ACID OXYGENASE; CYTOCHROME P450; SUBSTRATE BINDING; PALMITOLEATE, OXIDOREDUCTASE
2w09:A (PRO26) to (ALA65) CYP51 OF M. TUBERCULOSIS BOUND TO AN INHIBITOR CIS-4- METHYL-N-[(1S)-3-(METHYLSULFANYL)-1-(PYRIDIN-4- YLCARBAMOYL)PROPYL]CYCLOHEXANECARBOXAMIDE | STEROID BIOSYNTHESIS, PROTEIN-INHIBITOR COMPLEX, METAL-BINDING, OXIDOREDUCTASE, LIPID SYNTHESIS, NADP, IRON, HEME, CYTOPLASM, MONOOXYGENASE, X-RAY DIFFRACTION, STEROL BIOSYNTHESIS
1t93:A (ASP27) to (ASP66) EVIDENCE FOR MULTIPLE SUBSTRATE RECOGNITION AND MOLECULAR MECHANISM OF C-C REACTION BY CYTOCHROME P450 CYP158A2 FROM STREPTOMYCES COELICOLOR A3(2) | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP158A2, SUBSTRATE RECOGNITION, MOLECULAR MECHANISM, OXIDOREDUCTASE
3ivy:A (VAL40) to (SER86) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS CYTOCHROME P450 CYP125, P212121 CRYSTAL FORM | CHOLESTEROL, CYTOCHROME P450, TUBERCULOSIS, MONOOXYGENASE, HEME, IRON, METAL-BINDING, OXIDOREDUCTASE
3voo:A (ILE24) to (ASP59) CYTOCHROME P450SP ALPHA (CYP152B1) MUTANT A245E | CYTOCHROME P450, OXIDOREDUCTASE
5a5i:A (ILE47) to (GLY91) CYTOCHROME 2C9 P450 INHIBITOR COMPLEX | OXIDOREDUCTASE
3wec:A (PRO26) to (SER61) STRUCTURE OF P450 RAUA (CYP1050A1) COMPLEXED WITH A BIOSYNTHETIC INTERMEDIATE OF AURACHIN RE | P450 FOLD, MONOOXYGENASE (HYDROXYLASE), HEME, CYTOSOLIC ENZYME, OXIDOREDUCTASE
2ij4:A (PRO25) to (ASP63) STRUCTURE OF THE A264K MUTANT OF CYTOCHROME P450 BM3 | LYSINE HEME LIGATION, CYTOCHROME P450, P450 BM3, OXIDOREDUCTASE
2ij4:B (PRO25) to (CYS62) STRUCTURE OF THE A264K MUTANT OF CYTOCHROME P450 BM3 | LYSINE HEME LIGATION, CYTOCHROME P450, P450 BM3, OXIDOREDUCTASE
5akb:A (GLU431) to (ALA485) MUTS IN COMPLEX WITH THE N-TERMINAL DOMAIN OF MUTL - CRYSTAL FORM 1 | DNA BINDING PROTEIN, HYDROLASE, DNA MISMATCH REPAIR, COMPLEX, SLIDING CLAMP, CROSSLINKING
5akb:B (GLU431) to (ALA485) MUTS IN COMPLEX WITH THE N-TERMINAL DOMAIN OF MUTL - CRYSTAL FORM 1 | DNA BINDING PROTEIN, HYDROLASE, DNA MISMATCH REPAIR, COMPLEX, SLIDING CLAMP, CROSSLINKING
1jme:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF PHE393HIS CYTOCHROME P450 BM3 | CYTOCHROME P450, FATTY ACID HYDROXYLASE, MONOOXYGENASE, OXIDOREDUCTASE
1jme:B (PRO25) to (ASP63) CRYSTAL STRUCTURE OF PHE393HIS CYTOCHROME P450 BM3 | CYTOCHROME P450, FATTY ACID HYDROXYLASE, MONOOXYGENASE, OXIDOREDUCTASE
4nkx:A (MET49) to (GLY90) HUMAN STEROIDOGENIC CYTOCHROME P450 17A1 MUTANT A105L WITH SUBSTRATE PROGESTERONE | HEME PROTEIN, MONOOXYGENASE, STEROID 17ALPHA-HYDROXYLASE, STEROID C17,20 LYASE, NADPH-CYTOCHROME P450 REDUCTASE, CYTOCHROME B5, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE, LYASE
1x1u:A (ASP8) to (GLY34) WATER-MEDIATE INTERACTION AT APROTEIN-PROTEIN INTERFACE | RNASE-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE/PROTEIN BINDING COMPLEX
1x8v:A (PRO26) to (PHE63) ESTRIOL-BOUND AND LIGAND-FREE STRUCTURES OF STEROL 14ALPHA- DEMETHYLASE (CYP51) | ALPHA-BETA, HEME CO-FACTOR, PROTEIN-ESTRIOL COMPLEX, OXIDOREDUCTASE
2nnh:A (ILE50) to (GLY91) CYP2C8DH COMPLEXED WITH 2 MOLECULES OF 9-CIS RETINOIC ACID | CYP2C8; HUMAN P450 2C8; MONOOXYGENASES; SUBSTRATE COMPLEX; PALMITIC ACID; 9-CIS RETINOIC ACID; PANRETIN, OXIDOREDUCTASE,ELECTRON TRANSPORT
2nnh:B (CYS51) to (GLY91) CYP2C8DH COMPLEXED WITH 2 MOLECULES OF 9-CIS RETINOIC ACID | CYP2C8; HUMAN P450 2C8; MONOOXYGENASES; SUBSTRATE COMPLEX; PALMITIC ACID; 9-CIS RETINOIC ACID; PANRETIN, OXIDOREDUCTASE,ELECTRON TRANSPORT
3kx5:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF BACILLUS MEGATERIUM BM3 HEME DOMAIN MUTANT F261E | CYTOCHROME P450, F261E MUTANT, HEME DOMAIN, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3kx5:B (PRO25) to (CYS62) CRYSTAL STRUCTURE OF BACILLUS MEGATERIUM BM3 HEME DOMAIN MUTANT F261E | CYTOCHROME P450, F261E MUTANT, HEME DOMAIN, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3lhd:C (GLU37) to (LYS69) CRYSTAL STRUCTURE OF P. ABYSSI TRNA M1A58 METHYLTRANSFERASE IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE | RNA METHYLTRANSFERASE, M1A, TRMI, INTERMOLECULAR CONTACTS, REGION- SPECIFICITY, TETRAMER, DISULFIDE BOND, HYPERTHERMOSTABILITY, METHYLTRANSFERASE, TRANSFERASE
3lhd:B (GLU37) to (LYS69) CRYSTAL STRUCTURE OF P. ABYSSI TRNA M1A58 METHYLTRANSFERASE IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE | RNA METHYLTRANSFERASE, M1A, TRMI, INTERMOLECULAR CONTACTS, REGION- SPECIFICITY, TETRAMER, DISULFIDE BOND, HYPERTHERMOSTABILITY, METHYLTRANSFERASE, TRANSFERASE
5dyp:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF ASP251GLY/GLN307HIS MUTANT OF CYTOCHROME P450 BM3 | CYTOCHROME P450, RANDOM MUTAGENESIS, DRUG METABOLISM, OXIDOREDUCTASE
5dyp:C (PRO25) to (ASP63) CRYSTAL STRUCTURE OF ASP251GLY/GLN307HIS MUTANT OF CYTOCHROME P450 BM3 | CYTOCHROME P450, RANDOM MUTAGENESIS, DRUG METABOLISM, OXIDOREDUCTASE
5dyz:A (PRO25) to (ASP63) CRYSTAL STRUCTURE OF ASP251GLY/GLN307HIS MUTANT OF CYTOCHROME P450 BM3 IN COMPLEX WITH N-PALMITOYLGLYCINE | CYTOCHROME P450, RANDOM MUTAGENESIS, DRUG METABOLISM, SUBSTRATE, OXIDOREDUCTASE
5dyz:C (PRO25) to (ASP63) CRYSTAL STRUCTURE OF ASP251GLY/GLN307HIS MUTANT OF CYTOCHROME P450 BM3 IN COMPLEX WITH N-PALMITOYLGLYCINE | CYTOCHROME P450, RANDOM MUTAGENESIS, DRUG METABOLISM, SUBSTRATE, OXIDOREDUCTASE
4qc6:B (THR42) to (HIS87) CRYSTAL STRUCTURE OF AMINOGLYCOSIDE 6'-ACETYLTRANSFERASE-IE | ANTIBIOTIC RESISTANCE, GNAT FAMILY, ACETYLTRANSFERASE, ACETYLCOENZYME-A, AMINOGLYCOSIDE, TRANSFERASE, TRANSFERASE- ANTIBIOTIC COMPLEX
4c28:A (PHE55) to (PHE90) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- YLAMINO)PROPAN-2-YL)-4-(4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)- 2-FLUOROBENZAMIDE. | OXIDOREDUCTASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
3npl:A (PRO25) to (ALA62) STRUCTURE OF RU(BPY)2(A-PHEN)(K97C) P450 BM3 HEME DOMAIN, A RUTHENIUM MODIFIED P450 BM3 MUTANT | P450 BM3 HEME DOMAIN, MUTANT PROTEINS, ELECTRON TRANSFER, OXIDOREDUCTASE
3npl:B (PRO25) to (ASP63) STRUCTURE OF RU(BPY)2(A-PHEN)(K97C) P450 BM3 HEME DOMAIN, A RUTHENIUM MODIFIED P450 BM3 MUTANT | P450 BM3 HEME DOMAIN, MUTANT PROTEINS, ELECTRON TRANSFER, OXIDOREDUCTASE
4ck8:A (PHE55) to (PHE90) STEROL 14-ALPHA DEMETHYLASE (CYP51)FROM TRYPANOSOMA CRUZI IN COMPLEX WITH (R)-1-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL)ETHYL 4-(4-(3,4-DICHLOROPHENYL)PIPERAZIN-1-YL)PHENYLCARBAMATE (LFD) | CYTOCHROME P450, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE
4ck8:B (LEU53) to (PHE90) STEROL 14-ALPHA DEMETHYLASE (CYP51)FROM TRYPANOSOMA CRUZI IN COMPLEX WITH (R)-1-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL)ETHYL 4-(4-(3,4-DICHLOROPHENYL)PIPERAZIN-1-YL)PHENYLCARBAMATE (LFD) | CYTOCHROME P450, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE
4cka:A (PHE55) to (PHE90) STEROL 14-ALPHA DEMETHYLASE (CYP51)FROM TRYPANOSOMA CRUZI IN COMPLEX WITH (S)-1-(4-FLUOROPHENYL)-2-(1H-IMIDAZOL-1-YL) ETHYL 4-ISOPROPYLPHENYLCARBAMATE (LFS) | HEME, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE
4duc:A (PRO25) to (ASP63) CYTOCHROME P450 BM3H-2G9 MRI SENSOR, NO LIGAND | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4duc:B (PRO25) to (ASP63) CYTOCHROME P450 BM3H-2G9 MRI SENSOR, NO LIGAND | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4uhi:A (SER80) to (SER120) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN C121 SPACE GROUP | OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhi:D (PRO81) to (SER120) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN C121 SPACE GROUP | OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
3qi8:B (PRO25) to (ASP63) EVOLVED VARIANT OF CYTOCHROME P450 (BM3, CYP102A1) | CYTOCHROME P450, OXIDATION (NAPROXEN, IBUPROFEN), OXIDOREDUCTASE
3qi8:A (PRO25) to (ASP63) EVOLVED VARIANT OF CYTOCHROME P450 (BM3, CYP102A1) | CYTOCHROME P450, OXIDATION (NAPROXEN, IBUPROFEN), OXIDOREDUCTASE
4gqs:A (VAL50) to (GLY91) STRUCTURE OF HUMAN MICROSOMAL CYTOCHROME P450 (CYP) 2C19 | MONOOXYGENASE, DRUG METABOLIZING ENZYME, OXIDOREDUCTASE, HEME PROTEIN