2o8l:A (TYR24) to (THR48) STRUCTURE OF V8 PROTEASE FROM STAPHYLOCOCCUS AUREUS | SERINE PROTEASE; ENZYME, HYDROLASE
4wa0:A (ALA245) to (ASN262) THE STRUCTURE OF A POSSIBLE ADHESIN C-TERMINAL DOMAIN FROM CALDICELLULOSIRUPTOR KRONOTSKYENSIS | BETA-HELIX, CALDICELLULOSIRUPTOR, CELL ADHESION
4gs7:D (HIS11) to (ARG35) STRUCTURE OF THE INTERLEUKIN-15 QUATERNARY COMPLEX | CYTOKINE, CYTOKINE RECEPTOR, IMMUNOREGULATORY, ANTI-TUMOR, ANTI- VIRAL, REDUCTIVE METHYLATION, IMMUNE SYSTEM
2o9o:A (THR287) to (GLN310) CRYSTAL STRUCTURE OF THE BUFFALO SECRETORY SIGNALLING GLYCOPROTEIN AT 2.8 A RESOLUTION | SPB-40, TIM BARREL, SIGNALING PROTEIN
2o9r:A (SER415) to (GLN434) BETA-GLUCOSIDASE B COMPLEXED WITH THIOCELLOBIOSE | BETA-GLUCOSIDASE, GLYCOSYL HYDROLASE FAMILY 1, THIOCELLOBIOSE INHIBITOR
2o9t:A (SER415) to (GLN434) BETA-GLUCOSIDASE B FROM BACILLUS POLYMYXA COMPLEXED WITH GLUCOSE | BETA-GLUCOSIDASE, GLYCOSYL HYDROLASE FAMILY 1, GLUCOSE COMPLEX
3rkp:A (SER244) to (ASN266) CRYSTAL STRUCTURE OF BCPA*(D312A), THE MAJOR PILIN SUBUNIT OF BACILLUS CEREUS | INTRAMOLECULAR AMIDE BOND, JELLY-ROLL, IG, PILIN SUBUNIT, CELL ADHESION
1a0j:B (GLN30) to (SER54) CRYSTAL STRUCTURE OF A NON-PSYCHROPHILIC TRYPSIN FROM A COLD-ADAPTED FISH SPECIES. | SERINE PROTEINASE, TRYPSIN, HYDROLASE, SERINE PROTEASE
1a0j:C (TYR29) to (SER54) CRYSTAL STRUCTURE OF A NON-PSYCHROPHILIC TRYPSIN FROM A COLD-ADAPTED FISH SPECIES. | SERINE PROTEINASE, TRYPSIN, HYDROLASE, SERINE PROTEASE
3rlk:A (TYR251) to (SER279) CRYSTAL STRUCTURE OF THE READ-THROUGH DOMAIN FROM BACTERIOPHAGE QBETA A1 PROTEIN, MONOCLINIC CRYSTAL FORM | BETA-BARREL, POLYPROLINE HELIX, STRUCTURAL PROTEIN
3rlw:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH MI328 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, HIRUDIN, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3rly:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH MI329 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, HIRUDIN, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3rm0:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH MI354 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, HIRUDIN, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3rm4:B (GLN316) to (VAL339) AMCASE IN COMPLEX WITH COMPOUND 1 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3e8l:B (GLN30) to (SER52) THE CRYSTAL STRUCTURE OF THE DOUBLE-HEADED ARROWHEAD PROTEASE INHIBITOR A IN COMPLEX WITH TWO TRYPSINS | BETA-TREFOIL FOLD, PROTEASE INHIBITOR, TRYPSIN, COMPLEX, DIGESTION, HYDROLASE, METAL-BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, HYDROLASE INHIBITOR-HYDROLASE COMPLEX
3e90:B (VAL22) to (LEU49) WEST NILE VI RUS NS2B-NS3PROTEASE IN COMPLEXED WITH INHIBITOR NAPH-KKR-H | WEST NILE VIRUS, NS3 PROTEASE, TRYPSIN-LIKE SERINE PROTEASE, PROTEASE INHIBITOR, CRYSTAL STRUCTURE, CATALYTIC HISTIDINE, INDUCED FIT, ATP-BINDING, CAPSID PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, VIRION
3e90:D (VAL22) to (LEU49) WEST NILE VI RUS NS2B-NS3PROTEASE IN COMPLEXED WITH INHIBITOR NAPH-KKR-H | WEST NILE VIRUS, NS3 PROTEASE, TRYPSIN-LIKE SERINE PROTEASE, PROTEASE INHIBITOR, CRYSTAL STRUCTURE, CATALYTIC HISTIDINE, INDUCED FIT, ATP-BINDING, CAPSID PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, VIRION
4gu6:B (ARG421) to (ASN458) FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-{3-[(5-CYANO- 2-PHENYL-1H-PYRROLO[2,3-B]PYRIDIN-4-YLAMINO)- METHYL]-PYRIDIN-2-YL}- N-METHYL-METHANESULFONAMIDE | PROTEIN TYROSINE KINASE, ATP BINDING, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4gu8:F (GLY65) to (GLY96) CRYSTAL STRUCTURE OF BURKHOLDERIA OKLAHOMENSIS AGGLUTININ (BOA) | LECTIN, SUGAR BINDING, BETA BARREL, ANTI-HIV, MAN9, GLYCAN, GP120, SUGAR BINDING PROTEIN
4gu8:H (GLY198) to (GLY234) CRYSTAL STRUCTURE OF BURKHOLDERIA OKLAHOMENSIS AGGLUTININ (BOA) | LECTIN, SUGAR BINDING, BETA BARREL, ANTI-HIV, MAN9, GLYCAN, GP120, SUGAR BINDING PROTEIN
3rme:B (GLN316) to (VAL339) AMCASE IN COMPLEX WITH COMPOUND 5 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4wf8:A (LEU1104) to (LEU1127) CRYSTAL STRUCTURE OF NS3/4A PROTEASE IN COMPLEX WITH ASUNAPREVIR | HCV PROTEASE INHIBITOR COMPLEX, RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3rmm:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH MI332 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, HIRUDIN, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3rmn:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH MI341 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, HIRUDIN, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3eaj:B (VAL18) to (PRO39) CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE QUADRUPLE MUTANT STIF/A WITH TWO MOLECULES IN ONE ASYMMETRIC UNIT | SARS CORONAVIRUS MAIN PROTEASE MUTANT EXTRA HELICAL DOMAIN, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
1nd5:B (HIS1280) to (LEU1310) CRYSTAL STRUCTURES OF HUMAN PROSTATIC ACID PHOSPHATASE IN COMPLEX WITH A PHOSPHATE ION AND ALPHA-BENZYLAMINOBENZYLPHOSPHONIC ACID UPDATE THE MECHANISTIC PICTURE AND OFFER NEW INSIGHTS INTO INHIBITOR DESIGN | ACID PHOSPHATASE, PAP, PROSTATE, PHOSPHATE, INHIBITOR, HYDROLASE
1nd5:C (HIS2281) to (LEU2311) CRYSTAL STRUCTURES OF HUMAN PROSTATIC ACID PHOSPHATASE IN COMPLEX WITH A PHOSPHATE ION AND ALPHA-BENZYLAMINOBENZYLPHOSPHONIC ACID UPDATE THE MECHANISTIC PICTURE AND OFFER NEW INSIGHTS INTO INHIBITOR DESIGN | ACID PHOSPHATASE, PAP, PROSTATE, PHOSPHATE, INHIBITOR, HYDROLASE
1a79:A (GLY99) to (TYR128) CRYSTAL STRUCTURE OF THE TRNA SPLICING ENDONUCLEASE FROM METHANOCOCCUS JANNASCHII | ENDONUCLEASE, TRNA ENDONUCLEASE
1a8g:B (PRO9) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH SDZ283-910 | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ne8:A (ASP7) to (ALA49) YDCE PROTEIN FROM BACILLUS SUBTILIS | CONSERVED HYPOTHETICAL PROTEIN YDCE, STRUCTURAL GENOMICS, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NYSGXRC, UNKNOWN FUNCTION
1a94:A (ARG8) to (GLU34) STRUCTURAL BASIS FOR SPECIFICITY OF RETROVIRAL PROTEASES | HUMAN IMMUNODEFICIENCY VIRUS PROTEASE, ROUS SARCOMA VIRUS PROTEASE, PROTEIN-MEDIATED INTERACTION, VIRAL MATURATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4wh8:A (ASP1103) to (LEU1127) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH AN ASUNAPREVIR P1-P3 MACROCYCLIC ANALOG. | HCV DRUG RESISTANCE, PROTEASE-INHIBITOR COMPLEX, ASUNAPREVIR, MACROCYCLE
4wh8:B (ASP1103) to (LEU1127) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH AN ASUNAPREVIR P1-P3 MACROCYCLIC ANALOG. | HCV DRUG RESISTANCE, PROTEASE-INHIBITOR COMPLEX, ASUNAPREVIR, MACROCYCLE
4wha:A (SER39) to (GLU86) LIPOXYGENASE-1 (SOYBEAN) L546A/L754A MUTANT | LIPOXYGENASE, TUNNELING, C-H ACTIVATION, OXIDOREDUCTASE
3rp2:A (TYR29) to (THR54) THE STRUCTURE OF RAT MAST CELL PROTEASE II AT 1.9-ANGSTROMS RESOLUTION | SERINE PROTEINASE
1nfy:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH RPR200095 | HYDROLASE
2oit:A (GLN372) to (ASN407) CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE HUMAN PROTO-ONCOGENE NUP214/CAN | NH2 TERMINAL DOMAIN OF NUP214/CAN, X-RAY CRYSTALLOGRAPHY, BETA-PROPELLER, STRUCTURE, MRNA EXPORT, NPC ASSEMBLY, LEUKEMIA, NUP214/CAN FUSION, DBP5/DDX19, ONCOPROTEIN
2ar9:B (SER236) to (VAL260) CRYSTAL STRUCTURE OF A DIMERIC CASPASE-9 | CASPASE, CASPASE ACTIVATION, INITIATOR CASPASE, CYSTEINE PROTEASE, ENGINEERED CASPASE-9, HYDROLASE
2ar9:D (SER236) to (VAL260) CRYSTAL STRUCTURE OF A DIMERIC CASPASE-9 | CASPASE, CASPASE ACTIVATION, INITIATOR CASPASE, CYSTEINE PROTEASE, ENGINEERED CASPASE-9, HYDROLASE
2as9:A (GLY18) to (THR37) FUNCTIONAL AND STRUCTURAL CHARACTERIZATION OF SPL PROTEASES FROM STAPHYLOCOCCUS AUREUS | SERINE PROTEASE, TRYPSIN-LIKE FOLD, STAPHYLOCOCCUS AUREUS, HYDROLASE
2as9:A (GLY159) to (VAL188) FUNCTIONAL AND STRUCTURAL CHARACTERIZATION OF SPL PROTEASES FROM STAPHYLOCOCCUS AUREUS | SERINE PROTEASE, TRYPSIN-LIKE FOLD, STAPHYLOCOCCUS AUREUS, HYDROLASE
2as9:B (GLY18) to (THR37) FUNCTIONAL AND STRUCTURAL CHARACTERIZATION OF SPL PROTEASES FROM STAPHYLOCOCCUS AUREUS | SERINE PROTEASE, TRYPSIN-LIKE FOLD, STAPHYLOCOCCUS AUREUS, HYDROLASE
2as9:B (GLY159) to (PRO192) FUNCTIONAL AND STRUCTURAL CHARACTERIZATION OF SPL PROTEASES FROM STAPHYLOCOCCUS AUREUS | SERINE PROTEASE, TRYPSIN-LIKE FOLD, STAPHYLOCOCCUS AUREUS, HYDROLASE
2atf:A (ARG57) to (SER84) X-RAY STRUCTURE OF CYSTEINE DIOXYGENASE TYPE I FROM MUS MUSCULUS MM.241056 | MM.241056, PFAM05995.2 CDO_I, BC013638, CUPIN FAMILY, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS, CESG, OXIDOREDUCTASE
1ad8:H (GLN30) to (THR54) COMPLEX OF THROMBIN WITH AND INHIBITOR CONTAINING A NOVEL P1 MOIETY | COMPLEX (SERINE PROTEASE-INHIBITOR), HYDROLASE, SERINE PROTEASE, COAGULANT, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3rs1:B (GLY151) to (GLY177) MOUSE C-TYPE LECTIN-RELATED PROTEIN CLRG | C-TYPE LECTIN-LIKE, LIGAND OF NK RECEPTOR, NATURAL KILLER CELL RECEPTORS, SURFACE OF ACTIVATED T LYMPHOCYTES, IMMUNE SYSTEM
2olh:A (THR286) to (GLN310) CRYSTAL STRUCTURE OF A SIGNALLING PROTEIN (SPG-40) COMPLEX WITH CELLOBIOSE AT 2.78 A RESOLUTION | SUGAR, COMPLEX, SIGNALING PROTEIN
1nik:K (LYS18) to (HIS40) WILD TYPE RNA POLYMERASE II | TRANSFERASE, TRANSCRIPTION
1af9:A (LYS1174) to (GLY1210) TETANUS NEUROTOXIN C FRAGMENT | CLOSTRIDIAL NEUROTOXIN, TETANUS, RECEPTOR BINDING
1agj:B (LEU156) to (GLY188) EPIDERMOLYTIC TOXIN A FROM STAPHYLOCOCCUS AUREUS | HYDROLASE, SERINE PROTEASE
3efw:A (ASP132) to (PHE165) STRUCTURE OF AURORAA WITH PYRIDYL-PYRIMIDINE UREA INHIBITOR | AURORAA, STK6_HUMAN, ATP-BINDING, CELL CYCLE, KINASE, NUCLEOTIDE- BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE-INHIBITOR COMPLEX
2onc:D (PRO264) to (THR307) CRYSTAL STRUCTURE OF HUMAN DPP-4 | DPP4 PROTEIN-INHIBITOR COMPLEX, HYDROLASE
3egd:B (PHE441) to (GLU463) CRYSTAL STRUCTURE OF THE MAMMALIAN COPII-COAT PROTEIN SEC23A/24A COMPLEXED WITH THE SNARE PROTEIN SEC22 AND BOUND TO THE TRANSPORT SIGNAL SEQUENCE OF VESICULAR STOMATITIS VIRUS GLYCOPROTEIN | COPII COAT, TRANSPORT SIGNAL SEQUENCE, VESICLE, DISEASE MUTATION, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, GOLGI APPARATUS, MEMBRANE, PROTEIN TRANSPORT, TRANSPORT, PHOSPHOPROTEIN, TRANSMEMBRANE
3egx:B (PHE441) to (GLU463) CRYSTAL STRUCTURE OF THE MAMMALIAN COPII-COAT PROTEIN SEC23A/24A COMPLEXED WITH THE SNARE PROTEIN SEC22B AND BOUND TO THE TRANSPORT SIGNAL SEQUENCE OF THE SNARE PROTEIN BET1 | COPII COAT PROTEIN, VESICLE TRANSPORT, TRANSPORT SIGNAL SEQUENCE, DISEASE MUTATION, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, GOLGI APPARATUS, MEMBRANE, PROTEIN TRANSPORT, TRANSPORT, PHOSPHOPROTEIN, TRANSMEMBRANE
3eh1:A (PHE615) to (PRO636) CRYSTAL STRUCTURE OF THE HUMAN COPII-COAT PROTEIN SEC24B | COPII COAT PROTEIN, VESICLE TRANSPORT, TRANSPORT SIGNAL SEQUENCE, CYTOPLASM, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, GOLGI APPARATUS, MEMBRANE, PHOSPHOPROTEIN, PROTEIN TRANSPORT, TRANSPORT
4wmd:B (VAL18) to (PRO39) CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE MERS-COV 3CL PROTEASE (C148A) IN SPACEGROUP C2221 | 3CL PROTEASE, MERS, CORONAVIRUS, HYDROLASE
4wme:B (VAL18) to (PRO39) CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE MERS-COV 3CL PROTEASE (C148A) IN SPACEGROUP C2 | MERS, CORONAVIRUS, 3CL PROTEASE, HYDROLASE
4wmf:A (VAL18) to (PRO39) CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE MERS-COV 3CL PROTEASE (C148A) IN SPACEGROUP P212121 | MES, 3CL PROTEASE, CORONAVIRUS, HYDROLASE
3eh2:A (PHE108) to (GLN132) CRYSTAL STRUCTURE OF THE HUMAN COPII-COAT PROTEIN SEC24C | COPII-COAT PROTEIN, VESICLE TRANSPORT, CYTOPLASM, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, GOLGI APPARATUS, MEMBRANE, PHOSPHOPROTEIN, PROTEIN TRANSPORT, TRANSPORT
3eh2:B (PHE108) to (PRO131) CRYSTAL STRUCTURE OF THE HUMAN COPII-COAT PROTEIN SEC24C | COPII-COAT PROTEIN, VESICLE TRANSPORT, CYTOPLASM, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, GOLGI APPARATUS, MEMBRANE, PHOSPHOPROTEIN, PROTEIN TRANSPORT, TRANSPORT
1nmf:A (LEU2) to (PHE30) MAJOR COLD-SHOCK PROTEIN, NMR, 20 STRUCTURES | COLD SHOCK PROTEIN, TRANSCRIPTION REGULATION
2ool:B (ARG106) to (PRO135) CRYSTAL STRUCTURE OF THE CHROMOPHORE-BINDING DOMAIN OF AN UNUSUAL BACTERIOPHYTOCHROME RPBPHP3 FROM R. PALUSTRIS | BACTERIOPHYTOCHROME, PHOTOCONVERSION, PHOTORECEPTOR, BILIVERDIN, SIGNALING PROTEIN
1ak5:A (ARG393) to (ALA440) INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) FROM TRITRICHOMONAS FOETUS | DEHYDROGENASE, ALPHA-8-BETA-8 BARREL, TIM BARREL, PURINE METABOLISM, OXIDOREDUCTASE, TETRAMER, C4-TETRAMER
4h13:C (ASP100) to (PRO130) CRYSTAL STRUCTURE OF THE CYTOCHROME B6F COMPLEX FROM MASTIGOCLADUS LAMINOSUS WITH TDS | ALPHA HELIX, BETA SHEET, PLASTOQUINOL-PLASTOCYANIN OXIDOREDUCTASE, PLASTOCYANIN, THYLAKOID MEMBRANE, PHOTOSYNTHESIS
1no9:H (GLN30) to (THR54) DESIGN OF WEAKLY BASIC THROMBIN INHIBITORS INCORPORATING NOVEL P1 BINDING FUNCTIONS: MOLECULAR AND X-RAY CRYSTALLOGRAPHIC STUDIES. | COMPLEX (SERINE PROTEASE-INHIBITOR), BLOOD COAGULATION, SERINE PROTEINASE INHIBITION, N,N-DIPHENYLCARBAMOYL-AMINOGUANIDINE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4h1j:A (ASP424) to (CYS459) CRYSTAL STRUCTURE OF PYK2 WITH THE PYRAZOLE 13A | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2oq5:A (GLN30) to (SER54) CRYSTAL STRUCTURE OF DESC1, A NEW MEMBER OF THE TYPE II TRANSMEMBRANE SERINE PROTEINASES FAMILY | TYPE II TRANS-MEMBRANE SERINE PROTEINASES, TRYPSIN-LIKE SERINE PROTEASE, TUMOR MARKER, HYDROLASE
1an1:E (GLN30) to (SER54) LEECH-DERIVED TRYPTASE INHIBITOR/TRYPSIN COMPLEX | SERINE PROTEINASE INHIBITOR, TRYPTASE INHIBITION, NON- CLASSICAL KAZAL-TYPE INHIBITOR, COMPLEX (SERINE PROTEASE/INHIBITOR)
4wot:C (GLY209) to (ASP248) ROCK2 IN COMPLEX WITH 1426382-07-1 | TRANSFERASE
4wot:D (GLY209) to (CYS247) ROCK2 IN COMPLEX WITH 1426382-07-1 | TRANSFERASE
2b31:A (THR286) to (GLN310) CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN GOAT SIGNALLING PROTEIN WITH PENTASACCHARIDE AT 3.1 A RESOLUTION REVEALS LARGE SCALE CONFORMATIONAL CHANGES IN THE RESIDUES OF TIM BARREL | SIGNALLING PROTEIN, COMPLEX PENTASACCHARIDE, SIGNALING PROTEIN
1and:A (GLN30) to (SER54) ANIONIC TRYPSIN MUTANT WITH ARG 96 REPLACED BY HIS | TRYPSIN, ANIONIC, SERINE PROTEASE, HYDROLASE
3ry3:A (LEU61) to (SER81) PUTATIVE SOLUTE-BINDING PROTEIN FROM YERSINIA PESTIS. | STRUCTURAL GENOMICS, IDP00509, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, SOLUTE-BINDING, TRANSPORT PROTEIN
3ry8:A (ASP479) to (ALA508) STRUCTURAL BASIS FOR NOROVIRUS INHIBITION AND FUCOSE MIMICRY BY CITRATE | VIRAL PROTEIN
3ry8:B (ASP479) to (ALA508) STRUCTURAL BASIS FOR NOROVIRUS INHIBITION AND FUCOSE MIMICRY BY CITRATE | VIRAL PROTEIN
3rza:A (ASN88) to (ALA109) CRYSTAL STRUCTURE OF A TRIPEPTIDASE (SAV1512) FROM STAPHYLOCOCCUS AUREUS SUBSP. AUREUS MU50 AT 2.10 A RESOLUTION | PHOSPHORYLASE/HYDROLASE-LIKE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, HYDROLASE
3rza:B (ASN88) to (ALA109) CRYSTAL STRUCTURE OF A TRIPEPTIDASE (SAV1512) FROM STAPHYLOCOCCUS AUREUS SUBSP. AUREUS MU50 AT 2.10 A RESOLUTION | PHOSPHORYLASE/HYDROLASE-LIKE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, HYDROLASE
1aor:A (ARG284) to (GLU311) STRUCTURE OF A HYPERTHERMOPHILIC TUNGSTOPTERIN ENZYME, ALDEHYDE FERREDOXIN OXIDOREDUCTASE | OXIDOREDUCTASE
4h44:C (ASP100) to (PRO130) 2.70 A CYTOCHROME B6F COMPLEX STRUCTURE FROM NOSTOC PCC 7120 | ALPHA HELIX, BETA-SHEET, PLASTOQUINOL-PLASTOCYANIN OXIDOREDUCTASE, PLASTOCYANIN, THYLAKOID MEMBRANES, PHOTOSYNTHESIS
1nqy:A (ARG34) to (PHE68) THE STRUCTURE OF A COA PYROPHOSPHATASE FROM D. RADIODURANS | NUDIX, PYROPHOSPHATASE, DR1184, COA, HYDROLASE
3rzd:K (LYS18) to (HIS40) RNA POLYMERASE II INITIATION COMPLEX WITH A 5-NT RNA | RNA POLYMERASE II, INITIATION COMPLEX, TRANSCRIPTION-RNA-DNA COMPLEX
3rzh:A (LYS111) to (PRO133) DUPLEX INTERROGATION BY A DIRECT DNA REPAIR PROTEIN IN THE SEARCH OF DAMAGE | PROTEIN-DNA COMPLEX, JELLY-ROLL, DEMETHYLASE, NUCLEUS, OXIDOREDUCTASE-DNA COMPLEX
3rzj:A (LYS111) to (PRO133) DUPLEX INTERROGATION BY A DIRECT DNA REPAIR PROTEIN IN THE SEARCH OF DAMAGE | PROTEIN-DNA COMPLEX, JELLY-ROLL, DEMETHYLASE, NUCLEUS, OXIDOREDUCTASE-DNA COMPLEX
1arb:A (GLY26) to (THR54) THE PRIMARY STRUCTURE AND STRUCTURAL CHARACTERISTICS OF ACHROMOBACTER LYTICUS PROTEASE I, A LYSINE-SPECIFIC SERINE PROTEASE | HYDROLASE(SERINE PROTEASE)
1arc:A (VAL25) to (THR54) THE PRIMARY STRUCTURE AND STRUCTURAL CHARACTERISTICS OF ACHROMOBACTER LYTICUS PROTEASE I, A LYSINE-SPECIFIC SERINE PROTEASE | SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2b5h:A (ARG57) to (SER84) 1.5 A RESOLUTION CRYSTAL STRUCTURE OF RECOMBINANT R. NORVEGICUS CYSTEINE DIOXYGENASE | BETA-SANDWICH, JELLY-ROLL TOPOLOGY, CUPIN FOLD, TETRAHEDRAL IRON COORDINATION, OXIDOREDUCTASE
4wr3:B (GLY216) to (SER240) Y274F ALANINE RACEMASE FROM E. COLI | ISOMERASE
4wr3:D (GLY216) to (SER240) Y274F ALANINE RACEMASE FROM E. COLI | ISOMERASE
3el0:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF THE INHIBITOR NELFINAVIR (NFV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10I/G48V/I54V/V64I/V82A) (REFER: FLAP+ IN CITATION) | HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, NELFINAVIR, AIDS, HYDROLASE
3eln:A (ARG57) to (SER84) A PUTATIVE FE2+-BOUND PERSULFENATE INTERMEDIATE IN CYSTEINE DIOXYGENASE | PEROXYSULFENATE, NON-HEME DIOXYGENASES, FE2+ METALLOENZYME, CYSTEINE, TAURINE, THIOETHER, DIOXYGENASE, IRON, METAL- BINDING, OXIDOREDUCTASE, PHOSPHOPROTEIN, THIOETHER BOND
1auj:A (GLN30) to (SER54) BOVINE TRYPSIN COMPLEXED TO META-CYANO-BENZYLIC INHIBITOR | HYDROLASE, SERINE PROTEINASE
2owy:A (THR230) to (ARG252) THE RECOMBINATION-ASSOCIATED PROTEIN RDGC ADOPTS A NOVEL TOROIDAL ARCHITECTURE FOR DNA BINDING | HOMOLOGOUS RECOMBINATION, PSEUDOMONAS AERUGINOSA, RDGC, RECA, RING- SHAPED DNA BINDING PROTEINS, DNA BINDING PROTEIN
2oxe:B (SER437) to (TYR467) STRUCTURE OF THE HUMAN PANCREATIC LIPASE-RELATED PROTEIN 2 | GLYCOPROTEIN, HYDROLASE, LIPID DEGRADATION, PANCREATIC LIPASE, STRUCTURAL GENOMICS CONSORTIUM, SGC
1avg:H (GLN30) to (LEU53) THROMBIN INHIBITOR FROM TRIATOMA PALLIDIPENNIS | BOVINE THROMBIN, THROMBIN INHIBITOR, COMPLEX (BLOOD COAGULATION/INHIBITOR)
2oy3:A (GLN421) to (ASP447) CRYSTAL STRUCTURE ANALYSIS OF THE MONOMERIC SRCR DOMAIN OF MOUSE MARCO | EXTRACELLULAR MATRIX, SCAVENGER RECEPTOR CYSTEINE-RICH (SRCR), MACROPHAGE RECEPTOR, LIGAND BINDING DOMAIN, BASIC CLUSTER, ACIDIC CLUSTER, LIGAND BINDING PROTEIN
3ens:B (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN FXA IN COMPLEX WITH METHYL (2Z)-3-[(3- CHLORO-1H-INDOL-7-YL)AMINO]-2-CYANO-3-{[(3S)-2-OXO-1-(2-OXO-2- PYRROLIDIN-1-YLETHYL)AZEPAN-3-YL]AMINO}ACRYLATE | SERINE PROTEASE, HYDROLASE, EPIDERMAL GROWTH FACTOR LIKE DOMAIN, BLOOD COAGULATION FACTOR, CLEAVAGE ON PAIR OF BASIC RESIDUES, EGF- LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROXYLATION, ZYMOGEN, BLOOD CLOTTING
1avw:A (GLN30) to (SER54) COMPLEX PORCINE PANCREATIC TRYPSIN/SOYBEAN TRYPSIN INHIBITOR, ORTHORHOMBIC CRYSTAL FORM | COMPLEX (PROTEINASE/INHIBITOR), PORCINE TRYPSIN, SOYBEAN TRYPSIN INHIBITOR, KUNITZ-TYPE, BETA-TREFOIL FOLD
1avx:B (THR516) to (ASN548) COMPLEX PORCINE PANCREATIC TRYPSIN/SOYBEAN TRYPSIN INHIBITOR, TETRAGONAL CRYSTAL FORM | COMPLEX (PROTEINASE/INHIBITOR), PORCINE TRYPSIN, SOYBEAN TRYPSIN INHIBITOR, KUNITZ-TYPE, BETA-TREFOIL FOLD
2oyn:A (ILE80) to (PRO111) CRYSTAL STRUCTURE OF CDP-BOUND PROTEIN MJ0056 FROM METHANOCOCCUS JANNASCHII, PFAM DUF120 | STRUCTURAL GENOMICS, UNKNOWN FUNCTION, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
1awh:B (GLN30) to (THR54) NOVEL COVALENT THROMBIN INHIBITOR FROM PLANT EXTRACT | PROTEINASE, BLOOD COAGULATION, TRYPSIN LIKE PROTEINASE, COMPLEX (PROTEASE/INHIBITOR)
1awh:D (GLN30) to (THR54) NOVEL COVALENT THROMBIN INHIBITOR FROM PLANT EXTRACT | PROTEINASE, BLOOD COAGULATION, TRYPSIN LIKE PROTEINASE, COMPLEX (PROTEASE/INHIBITOR)
3s16:B (THR1170) to (HIS1195) RNA POLYMERASE II INITIATION COMPLEX WITH AN 8-NT RNA | RNA POLYMERASE II, INITIATION COMPLEX, TRANSCRIPTION-RNA-DNA COMPLEX
1axa:A (PRO9) to (GLU34) ACTIVE-SITE MOBILITY IN HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE AS DEMONSTRATED BY CRYSTAL STRUCTURE OF A28S MUTANT | HIV PROTEASE, MUTANT, X-RAY, ASPARTIC PROTEASE, HYDROLASE, ACID PROTEINASE, ASPARTYL PROTEASE
1axa:B (PRO9) to (GLU34) ACTIVE-SITE MOBILITY IN HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE AS DEMONSTRATED BY CRYSTAL STRUCTURE OF A28S MUTANT | HIV PROTEASE, MUTANT, X-RAY, ASPARTIC PROTEASE, HYDROLASE, ACID PROTEINASE, ASPARTYL PROTEASE
4ha2:A (VAL119) to (ASP148) CRYSTAL STRUCTURE OFA PHENYL ALANINE 91 MUTANT OF WCI | CHYMOTRYPSIN INHIBITOR, WCI, HYDROLASE INHIBITOR
4ha2:B (VAL319) to (ASP348) CRYSTAL STRUCTURE OFA PHENYL ALANINE 91 MUTANT OF WCI | CHYMOTRYPSIN INHIBITOR, WCI, HYDROLASE INHIBITOR
2ozf:A (GLY165) to (GLU201) THE CRYSTAL STRUCTURE OF THE 2ND PDZ DOMAIN OF THE HUMAN NHERF-1 (SLC9A3R1) | PDZ DOMAIN, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, PROTEIN BINDING
3s17:K (LYS18) to (HIS40) RNA POLYMERASE II INITIATION COMPLEX WITH A 9-NT RNA | RNA POLYMERASE II, INITIATION COMPLEX, TRANSCRIPTION-RNA-DNA HYBRID COMPLEX, TRANSCRIPTION-RNA-DNA COMPLEX
2b8k:I (GLU82) to (SER112) 12-SUBUNIT RNA POLYMERASE II | DNA-DIRECTED RNA POLYMERASE, DNA-DEPENDENT RNA POLYMERASE, CELLULAR RNA POLYMERASE, METAL-BINDING, NUCLEAR PROTEIN, TRANSCRIPTION, TRANSFERASE
4wt4:A (MET324) to (LEU347) THE C-TERMINAL DOMAIN OF RUBISCO ACCUMULATION FACTOR 1 FROM ARABIDOPSIS THALIANA, CRYSTAL FORM I | CHAPERONE
4hau:B (GLY109) to (PRO142) CRYSTAL STRUCTURE OF CRM1 INHIBITOR RATJADONE A IN COMPLEX WITH CRM1- RAN-RANBP1 | HEAT REPEAT, NUCLEAR EXPORT, RAN-RANBP1, RATJADONE A, PROTEIN TRANSPORT-ANTIBIOTIC COMPLEX
1azz:B (HIS29) to (THR54) FIDDLER CRAB COLLAGENASE COMPLEXED TO ECOTIN | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEASE, INHIBITOR, COMPLEX, PROTEASE-SUBSTRATE INTERACTIONS, COLLAGEN
1b04:B (VAL120) to (ILE144) STRUCTURE OF THE ADENYLATION DOMAIN OF AN NAD+ DEPENDENT LIGASE | LIGASE, DNA REPLICATION
3eq5:A (THR145) to (CYS166) CRYSTAL STRUCTURE OF FRAGMENT 137 TO 238 OF THE HUMAN SKI-LIKE PROTEIN | SKIL,SKI-LIKE PROTEIN,SNO,RECEPTOR SIGNALLING, TGF-BETA, SIGNALING PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC
3eq5:B (GLU143) to (CYS166) CRYSTAL STRUCTURE OF FRAGMENT 137 TO 238 OF THE HUMAN SKI-LIKE PROTEIN | SKIL,SKI-LIKE PROTEIN,SNO,RECEPTOR SIGNALLING, TGF-BETA, SIGNALING PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC
3eq5:C (THR145) to (CYS166) CRYSTAL STRUCTURE OF FRAGMENT 137 TO 238 OF THE HUMAN SKI-LIKE PROTEIN | SKIL,SKI-LIKE PROTEIN,SNO,RECEPTOR SIGNALLING, TGF-BETA, SIGNALING PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC
3eq5:D (THR145) to (CYS166) CRYSTAL STRUCTURE OF FRAGMENT 137 TO 238 OF THE HUMAN SKI-LIKE PROTEIN | SKIL,SKI-LIKE PROTEIN,SNO,RECEPTOR SIGNALLING, TGF-BETA, SIGNALING PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC
3eq5:F (THR145) to (CYS166) CRYSTAL STRUCTURE OF FRAGMENT 137 TO 238 OF THE HUMAN SKI-LIKE PROTEIN | SKIL,SKI-LIKE PROTEIN,SNO,RECEPTOR SIGNALLING, TGF-BETA, SIGNALING PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC
3eq5:G (THR145) to (CYS166) CRYSTAL STRUCTURE OF FRAGMENT 137 TO 238 OF THE HUMAN SKI-LIKE PROTEIN | SKIL,SKI-LIKE PROTEIN,SNO,RECEPTOR SIGNALLING, TGF-BETA, SIGNALING PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC
3eq5:H (GLU143) to (CYS166) CRYSTAL STRUCTURE OF FRAGMENT 137 TO 238 OF THE HUMAN SKI-LIKE PROTEIN | SKIL,SKI-LIKE PROTEIN,SNO,RECEPTOR SIGNALLING, TGF-BETA, SIGNALING PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC
3eq5:I (THR145) to (CYS166) CRYSTAL STRUCTURE OF FRAGMENT 137 TO 238 OF THE HUMAN SKI-LIKE PROTEIN | SKIL,SKI-LIKE PROTEIN,SNO,RECEPTOR SIGNALLING, TGF-BETA, SIGNALING PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC
3eq5:J (THR145) to (CYS166) CRYSTAL STRUCTURE OF FRAGMENT 137 TO 238 OF THE HUMAN SKI-LIKE PROTEIN | SKIL,SKI-LIKE PROTEIN,SNO,RECEPTOR SIGNALLING, TGF-BETA, SIGNALING PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC
3eq5:K (THR145) to (CYS166) CRYSTAL STRUCTURE OF FRAGMENT 137 TO 238 OF THE HUMAN SKI-LIKE PROTEIN | SKIL,SKI-LIKE PROTEIN,SNO,RECEPTOR SIGNALLING, TGF-BETA, SIGNALING PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC
3eq5:L (THR145) to (CYS166) CRYSTAL STRUCTURE OF FRAGMENT 137 TO 238 OF THE HUMAN SKI-LIKE PROTEIN | SKIL,SKI-LIKE PROTEIN,SNO,RECEPTOR SIGNALLING, TGF-BETA, SIGNALING PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC
3s1m:K (LYS18) to (HIS40) RNA POLYMERASE II INITIATION COMPLEX WITH A 5-NT RNA (VARIANT 1) | RNA POLYMERASE II, INITIATION COMPLEX, TRANSCRIPTION-RNA-DNA COMPLEX
2p16:A (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH THE INHIBITOR APIXABAN (BMS- 562247) AKA 1-(4-METHOXYPHENYL)-7-OXO-6-(4-(2-OXO-1- PIPERIDINYL)PHENYL)-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3, 4- C]PYRIDINE-3-CARBOXAMIDE | GLYCOPROTEIN, HYDROLASE, SERINE PROTEASE, PLASMA, BLOOD COAGULATION FACTOR, PROTEIN INHIBITOR COMPLEX, CALCIUM- BINDING
2p1g:A (ILE194) to (HIS223) CRYSTAL STRUCTURE OF A PUTATIVE XYLANASE FROM BACTEROIDES FRAGILIS | STRUCTURAL GENOMICS, UNKNOWN FUNCTION, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
2p1g:B (ILE194) to (HIS223) CRYSTAL STRUCTURE OF A PUTATIVE XYLANASE FROM BACTEROIDES FRAGILIS | STRUCTURAL GENOMICS, UNKNOWN FUNCTION, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
4haz:B (GLY109) to (PRO142) CRYSTAL STRUCTURE OF CRM1 INHIBITOR LEPTOMYCIN B IN COMPLEX WITH CRM1(R543S,K548E,K579Q)-RAN-RANBP1 | HEAT REPEAT, NUCLEAR EXPORT, RAN-RANBP1, LMB, LEPTOMYCIN B, PROTEIN TRANSPORT-ANTIBIOTIC COMPLEX
3s1n:K (LYS18) to (HIS40) RNA POLYMERASE II INITIATION COMPLEX WITH A 5-NT RNA (VARIANT 2) | RNA POLYMERASE II, INITIATION COMPLEX, TRANSCRIPTION-RNA-DNA COMPLEX
1nyk:A (GLY55) to (SER96) CRYSTAL STRUCTURE OF THE RIESKE PROTEIN FROM THERMUS THERMOPHILUS | BETA BARREL, IRON SULFUR CLUSTER, ELECTRON TRANSPORT
4hb2:B (GLY109) to (PRO142) CRYSTAL STRUCTURE OF CRM1-RAN-RANBP1 | HEAT REPEAT, NUCLEAR EXPORT, RAN-RANBP1, PROTEIN TRANSPORT
4hb3:B (GLU143) to (ALA165) CRYSTAL STRUCTURE OF CRM1(T539S)-RAN-RANBP1 WITH WEAKLY BOUND UNMODELED LEPTOMYCIN B | HEAT REPEAT, NUCLEAR EXPORT, RAN-RANBP1, LMB, LEPTOMYCIN B, PROTEIN TRANSPORT-ANTIBIOTIC COMPLEX
2bas:A (LEU15) to (GLY48) CRYSTAL STRUCTURE OF THE BACILLUS SUBTILIS YKUI PROTEIN, WITH AN EAL DOMAIN. | CRYSTAL STRUCTURE,YKUI PROTEIN, EAL DOMAIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, SIGNALING PROTEIN
3eqn:B (ASP488) to (ASP521) CRYSTAL STRUCTURE OF BETA-1,3-GLUCANASE FROM PHANEROCHAETE CHRYSOSPORIUM (LAM55A) | TANDEM BETA-HELIX DOMAINS, GLYCOSIDASE, HYDROLASE
2p4e:A (GLN454) to (SER485) CRYSTAL STRUCTURE OF PCSK9 | PROTEASE, SUBTILISIN, LDL RECEPTOR, LDL, ENDOCYTOSIS, HYDROLASE
2p4j:C (MET18) to (GLY41) CRYSTAL STRUCTURE OF BETA-SECRETASE BOND TO AN INHIBITOR WITH ISOPHTHALAMIDE DERIVATIVES AT P2-P3 | BETA-SECRETASE, MEMAPSIN, BACE, ASP, ASPARTIC PROTEASE, ACID PROTEASE, ALZHEIMER'S DISEASE, DRUG DESIGN, STRUCTURE BASED DRUG DESIGN, HYDROLASE
3s24:A (ASN465) to (THR504) CRYSTAL STRUCTURE OF HUMAN MRNA GUANYLYLTRANSFERASE | CAPPING ENZYME, CE, HCE, GTASE, M7GPPPN CAP, GT/DNA LIGASE FOLD, TRANSCRIPTION FACTOR SPT5, CTD, HYDROLASE, TRANSFERASE
2bdy:A (GLN51) to (THR76) THROMBIN IN COMPLEX WITH INHIBITOR | THROMBIN, COMPLEX STRUCTURE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4wz9:A (GLY524) to (MET559) APN1 FROM ANOPHELES GAMBIAE | AMINOPEPTIDASE, METALLOPROTEASE
4wz9:B (GLY524) to (MET559) APN1 FROM ANOPHELES GAMBIAE | AMINOPEPTIDASE, METALLOPROTEASE
2p8o:C (LEU199) to (ALA229) CRYSTAL STRUCTURE OF A BENZOHYDROXAMIC ACID/VANADATE COMPLEX BOUND TO CHYMOTRYPSIN A | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
2bfy:B (ASP92) to (PHE125) COMPLEX OF AURORA-B WITH INCENP AND HESPERADIN. | TRANSFERASE, KINASE, MITOSIS, INHIBITION, TRANSFERASE COMPLEX
3s2d:K (LYS18) to (HIS40) RNA POLYMERASE II INITIATION COMPLEX WITH A 5-NT RNA CONTAINING A 5BR- U | RNA POLYMERASE II, INITIATION COMPLEX, TRANSCRIPTION-RNA-DNA COMPLEX
4wzn:B (LEU864) to (ASN895) CRYSTAL STRUCTURE OF THE 2B PROTEIN SOLUBLE DOMAIN FROM HEPATITIS A VIRUS | FIBER, VIRAL RECRUITMENT MACHINERY, VIRAL PROTEIN, HEPATITIS A VIRUS, NON-STRUCTURAL PROTEIN
1bbg:A (GLY3) to (ASP30) RAGWEED POLLEN ALLERGEN FROM AMBROSIA TRIFIDA V, NMR, MINIMIZED AVERAGE STRUCTURE | PROTEIN ALLERGEN, SMALL HIGHLY DISULFIDE BONDED
1bbr:H (GLN30) to (THR54) THE STRUCTURE OF RESIDUES 7-16 OF THE A ALPHA CHAIN OF HUMAN FIBRINOGEN BOUND TO BOVINE THROMBIN AT 2.3 ANGSTROMS RESOLUTION | SERINE PROTEASE
1bbr:N (GLN30) to (THR54) THE STRUCTURE OF RESIDUES 7-16 OF THE A ALPHA CHAIN OF HUMAN FIBRINOGEN BOUND TO BOVINE THROMBIN AT 2.3 ANGSTROMS RESOLUTION | SERINE PROTEASE
2p94:A (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH THE INHIBITOR 3-CHLORO-N-((1R,2S)- 2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)CYCLOHEXYL)-1H- INDOLE-6-CARBOXAMIDE | GLYCOPROTEIN, HYDROLASE, SERINE PROTEASE, PLASMA, BLOOD COAGULATION FACTOR, PROTEIN INHIBITOR COMPLEX, CALCIUM- BINDING
2bgo:A (VAL64) to (GLN89) MANNAN BINDING MODULE FROM MAN5C | CARBOHYDRATE BINDING PROTEIN, MANNAN, CARBOHYDRATE BINDING MODULE
1bcu:H (GLN30) to (THR54) ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND PROFLAVIN | COMPLEX (SERINE PROTEASE INHIBITOR), HYDROLASE, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4x0l:C (ALA177) to (LEU198) HUMAN HAPTOGLOBIN-HAEMOGLOBIN COMPLEX | HAPTOGLOBIN-HAEMOGLOBIN COMPLEX, OXYGEN TRANSPORT
4hi8:B (SER-3) to (HIS32) STRUCTURE OF INTEGRIN-LINKED KINASE ANKYRIN REPEAT DOMAIN IN COMPLEX WITH PINCH1 LIM1 DOMAIN COLLECTED AT HIGH ENERGY, WAVELENGTH 0.32800 | ANKYRIN REPEAT LIM DOMAIN, SIGNALING PROTEIN-SIGNALING PROTEIN COMPLEX, ILK-PINCH, FOCAL ADHESION, SIGNALING PROTEIN
4hi9:B (SER-3) to (HIS32) 1.2 STRUCTURE OF INTEGRIN-LINKED KINASE ANKYRIN REPEAT DOMAIN IN COMPLEX WITH PINCH1 LIM1 DOMAIN COLLECTED AT WAVELENGTH 0.91974 | ANKYRIN REPEAT LIM DOMAIN, SIGNALING PROTEIN-SIGNALING PROTEIN COMPLEX, ILK-PINCH, FOCAL ADHESION, SIGNALING PROTEIN
4x1w:B (GLY510) to (GLY537) CRYSTAL STRUCTURE OF UNBOUND RHDVB P DOMAIN | MAJOR CAPSID PROTEIN, CAPSID SPIKE, PROTRUDING DOMAIN, DIMER, HBGA BINDING, VIRAL PROTEIN
4x1w:D (GLY510) to (GLY537) CRYSTAL STRUCTURE OF UNBOUND RHDVB P DOMAIN | MAJOR CAPSID PROTEIN, CAPSID SPIKE, PROTRUDING DOMAIN, DIMER, HBGA BINDING, VIRAL PROTEIN
4x1x:A (GLY510) to (GLY537) CRYSTAL STRUCTURE OF RHDVB P DOMAIN IN COMPLEX WITH LEWIS Y | MAJOR CAPSID PROTEIN, CAPSID SPIKE, PROTRUDING DOMAIN, HBGA BINDING, VIRAL PROTEIN
1bit:A (GLN30) to (SER54) THE CRYSTAL STRUCTURE OF ANIONIC SALMON TRYPSIN IN A SECOND CRYSTAL FORM | SERINE PROTEINASE
1o2z:A (GLN30) to (SER54) ELABORATE MANIFOLD OF SHORT HYDROGEN BOND ARRAYS MEDIATING BINDING OF ACTIVE SITE-DIRECTED SERINE PROTEASE INHIBITORS | SERINE PROTEASE, SHORT HYDROGEN BOND, INHIBITION MECHANISM, SHIFT OF PKA, TRYPSIN, THROMBIN, UROKINASE, FACTOR XA, HYDROLASE
4hnd:A (PRO127) to (PRO153) CRYSTAL STUCTURE OF THE CATALYTIC DOMAIN OF SELENOMETHIONINE SUBSTITUTED HUMAN PI4KIIALPHA IN COMPLEX WITH ADP | PI3K/PI4K KINASE, LIPID KINASE, ATP BINDING, PALMITOYLATION, MEMBRANE ANCHORING, TRANSFERASE
2bmc:B (ASP132) to (PHE165) AURORA-2 T287D T288D COMPLEXED WITH PHA-680632 | CELL CYCLE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, PHOSPHORYLATION
2bmc:C (ASP132) to (PHE165) AURORA-2 T287D T288D COMPLEXED WITH PHA-680632 | CELL CYCLE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, PHOSPHORYLATION
2bmc:E (ASP132) to (PHE165) AURORA-2 T287D T288D COMPLEXED WITH PHA-680632 | CELL CYCLE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, PHOSPHORYLATION
2pfe:A (ASN31) to (ALA55) CRYSTAL STRUCTURE OF THERMOBIFIDA FUSCA PROTEASE A (TFPA) | BETA-BARRELS; SERINE PROTEASE; THERMOPHILE; KINETIC STABILITY; THERMOSTABILITY; PROTEIN FOLDING; ALPHA-LYTIC PROTEASE; FOLDING TRANSITION STATE STRUCTURE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2pfe:B (ASN31) to (ALA55) CRYSTAL STRUCTURE OF THERMOBIFIDA FUSCA PROTEASE A (TFPA) | BETA-BARRELS; SERINE PROTEASE; THERMOPHILE; KINETIC STABILITY; THERMOSTABILITY; PROTEIN FOLDING; ALPHA-LYTIC PROTEASE; FOLDING TRANSITION STATE STRUCTURE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1o5d:H (GLN30) to (VAL53) DISSECTING AND DESIGNING INHIBITOR SELECTIVITY DETERMINANTS AT THE S1 SITE USING AN ARTIFICIAL ALA190 PROTEASE (ALA190 UPA) | ALA190 UPA, S1 SITE, SELECTIVITY, CONSERVED WATER DISPLACEMENT HYDROGEN BOND DEFICIT, TRYPSIN, THROMBIN, HEPSIN, FACTOR VIIA, BLOOD CLOTTING, HYDROLASE
1o5e:H (GLN30) to (LEU53) DISSECTING AND DESIGNING INHIBITOR SELECTIVITY DETERMINANTS AT THE S1 SITE USING AN ARTIFICIAL ALA190 PROTEASE (ALA190 UPA) | SRCR, SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN, SERINE PROTEASE ALA190 UPA, S1 SITE, SELECTIVITY, CONSERVED WATER DISPLACEMENT HYDROGEN BOND DEFICIT, TRYPSIN, THROMBIN, HEPSIN, FACTOR VIIA, SERINE PROTEASE, HYDROLASE
1o5f:H (GLN30) to (LEU53) DISSECTING AND DESIGNING INHIBITOR SELECTIVITY DETERMINANTS AT THE S1 SITE USING AN ARTIFICIAL ALA190 PROTEASE (ALA190 UPA) | SRCR, SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN, SERINE PROTEASE ALA190 UPA, S1 SITE, SELECTIVITY, CONSERVED WATER DISPLACEMENT HYDROGEN BOND DEFICIT, TRYPSIN, THROMBIN, HEPSIN, FACTOR VIIA, SERINE PROTEASE, HYDROLASE
1o5g:H (GLN30) to (THR54) DISSECTING AND DESIGNING INHIBITOR SELECTIVITY DETERMINANTS AT THE S1 SITE USING AN ARTIFICIAL ALA190 PROTEASE (ALA190 UPA) | ALA190 UPA, S1 SITE, SELECTIVITY, CONSERVED WATER DISPLACEMENT HYDROGEN BOND DEFICIT, TRYPSIN, THROMBIN, HEPSIN, FACTOR VIIA, BLOOD CLOTTING, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, BLOOD CLOTTING,HYDROLASE-INHIBITOR COMPLEX
1bmm:H (GLN30) to (LEU53) HUMAN ALPHA-THROMBIN COMPLEXED WITH [S-(R*,R*)]-4-[(AMINOIMINOMETHYL) AMINO]-N-[[1-[3-HYDROXY-2-[(2-NAPHTHALENYLSULFONYL)AMINO]-1- OXOPROPYL]-2-PYRROLIDINYL] METHYL]BUTANAMIDE (BMS-186282) | SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3f4a:A (VAL38) to (ALA55) STRUCTURE OF YGR203W, A YEAST PROTEIN TYROSINE PHOSPHATASE OF THE RHODANESE FAMILY | PROTEIN PHOSPHATASE, RHODANESE-LIKE FAMILY, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, HYDROLASE
3f4a:B (VAL38) to (ALA55) STRUCTURE OF YGR203W, A YEAST PROTEIN TYROSINE PHOSPHATASE OF THE RHODANESE FAMILY | PROTEIN PHOSPHATASE, RHODANESE-LIKE FAMILY, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, HYDROLASE
2bok:A (GLN30) to (THR54) FACTOR XA - CATION | SERINE PROTEASE, COAGULATION FACTOR, CATION, INHIBITOR, EGF- LIKE DOMAIN, HYDROLASE, PLASMA, PROTEASE
4x67:K (LYS18) to (HIS40) CRYSTAL STRUCTURE OF ELONGATING YEAST RNA POLYMERASE II STALLED AT OXIDATIVE CYCLOPURINE DNA LESIONS. | POL II ELONGATION COMPLEX OXIDATIVE CYCLOPURINE DNA LESIONS, TRANSCRIPTION-DNA COMPLEX
1bqb:A (LEU28) to (GLU55) AUREOLYSIN, STAPHYLOCOCCUS AUREUS METALLOPROTEINASE | HYDROLASE, METALLOPROTEINASE
1bqy:B (LEU30) to (THR54) PLASMINOGEN ACTIVATOR (TSV-PA) FROM SNAKE VENOM | FIBRINOLYSIS, PLASMINOGEN ACTIVATOR, SERINE PROTEINASE, SNAKE VENOM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, BLOOD CLOTTING
2bq6:B (GLN30) to (THR54) CRYSTAL STRUCTURE OF FACTOR XA IN COMPLEX WITH 21 | BLOOD COAGULATION, BLOOD COAGULATION FACTOR, CALCIUM- BINDING, EGF-LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, HYDROXYLATION, PLASMA, POLYMORPHISM, PROTEIN INHIBITOR COMPLEX, SERINE PROTEINASE, SERINE PROTEASE, VITAMIN K, ZYMOGEN
2bq7:B (GLN30) to (THR54) CRYSTAL STRUCTURE OF FACTOR XA IN COMPLEX WITH 43 | BLOOD COAGULATION, BLOOD COAGULATION FACTOR, CALCIUM- BINDING, EGF-LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, HYDROXYLATION, PLASMA, POLYMORPHISM, PROTEIN INHIBITOR COMPLEX, SERINE PROTEINASE, SERINE PROTEASE, VITAMIN K, ZYMOGEN
2bqv:A (ARG8) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR AHA455 | HYDROLASE/INHIBITOR, HYDROLASE/INHIBITOR COMPLEX, HIV-1 PROTEASE, INHIBITOR, DRUG DESIGN, HYDROLASE COMPLEX
3f6i:B (MSE138) to (PRO175) STRUCTURE OF THE SEMET LABELED F4 FIBRIAL CHAPERONE FAEE | IMMUNOGLOBULIN-LIKE FOLD, CELL PROJECTION, CHAPERONE, FIMBRIUM, IMMUNOGLOBULIN DOMAIN, PERIPLASM, PLASMID
1br1:A (ALA46) to (SER71) SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.ALF4 BOUND AT THE ACTIVE SITE | MUSCLE PROTEIN
1br1:C (ALA46) to (SER71) SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.ALF4 BOUND AT THE ACTIVE SITE | MUSCLE PROTEIN
1br1:E (ALA46) to (SER71) SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.ALF4 BOUND AT THE ACTIVE SITE | MUSCLE PROTEIN
1br1:G (ALA46) to (SER71) SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.ALF4 BOUND AT THE ACTIVE SITE | MUSCLE PROTEIN
3s7k:B (GLN30) to (THR54) STRUCTURE OF THROMBIN MUTANT Y225P IN THE E FORM | SERINE PROTEASE, HYDROLASE
4hok:O (LYS8) to (CYS41) CRYSTAL STRUCTURE OF APO CK1E | CK1E, KINASE, INHIBITOR, PF 4800567, TRANSFERASE
3s83:A (THR305) to (PRO338) EAL DOMAIN OF PHOSPHODIESTERASE PDEA | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, SIGNALING PROTEIN
1br4:A (ALA46) to (SER71) SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.BEF3 BOUND AT THE ACTIVE SITE | MUSCLE PROTEIN
1br4:C (ALA46) to (SER71) SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.BEF3 BOUND AT THE ACTIVE SITE | MUSCLE PROTEIN
1br4:E (ALA46) to (SER71) SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.BEF3 BOUND AT THE ACTIVE SITE | MUSCLE PROTEIN
1br4:G (ALA46) to (SER71) SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.BEF3 BOUND AT THE ACTIVE SITE | MUSCLE PROTEIN
1brb:E (GLN30) to (SER54) CRYSTAL STRUCTURES OF RAT ANIONIC TRYPSIN COMPLEXED WITH THE PROTEIN INHIBITORS APPI AND BPTI | COMPLEX(PROTEINASE/INHIBITOR)
4x7e:A (GLY332) to (TRP381) CRYSTAL STRUCTURE OF NOROVIRUS GII.10 P DOMAIN IN COMPLEX WITH NANO-85 | NANOBODY, VHH DOMAIN, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4x7e:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF NOROVIRUS GII.10 P DOMAIN IN COMPLEX WITH NANO-85 | NANOBODY, VHH DOMAIN, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4x7e:B (GLY332) to (TRP381) CRYSTAL STRUCTURE OF NOROVIRUS GII.10 P DOMAIN IN COMPLEX WITH NANO-85 | NANOBODY, VHH DOMAIN, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4x7e:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF NOROVIRUS GII.10 P DOMAIN IN COMPLEX WITH NANO-85 | NANOBODY, VHH DOMAIN, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
1brc:E (GLN30) to (SER54) RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN | COMPLEX(PROTEINASE/INHIBITOR)
4x7f:A (GLY332) to (TRP381) CRYSTAL STRUCTURE OF NOROVIRUS GII.10 P DOMAIN IN COMPLEX WITH NANO-25 | NANOBODY, VHH DOMAIN, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4x7f:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF NOROVIRUS GII.10 P DOMAIN IN COMPLEX WITH NANO-25 | NANOBODY, VHH DOMAIN, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4x7f:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF NOROVIRUS GII.10 P DOMAIN IN COMPLEX WITH NANO-25 | NANOBODY, VHH DOMAIN, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
3s8k:A (MET125) to (LYS181) CRYSTAL STRUCTURE OF A PAPAYA LATEX SERINE PROTEASE INHIBITOR (PPI) AT 1.7A RESOLUTION | KUNITZ-STI FOLD, PROTEASE INHIBITOR, HYDROLASE INHIBITOR
3s8k:B (MET125) to (LYS181) CRYSTAL STRUCTURE OF A PAPAYA LATEX SERINE PROTEASE INHIBITOR (PPI) AT 1.7A RESOLUTION | KUNITZ-STI FOLD, PROTEASE INHIBITOR, HYDROLASE INHIBITOR
3s8v:B (GLU631) to (ILE656) CRYSTAL STRUCTURE OF LRP6-DKK1 COMPLEX | WNT, RECEPTOR, LRP5, LRP6, LDL RECEPTOR-LIKE PROTEIN, DICKKOPF (DKK), YWTD B-PROPELLER, SIGNALING PROTEIN
2bsf:A (GLN196) to (GLY235) STRUCTURE OF THE C-TERMINAL RECEPTOR-BINDING DOMAIN OF AVIAN REOVIRUS FIBRE SIGMAC, ZN CRYSTAL FORM. | ORTHOREOVIRUS, TRIPLE BETA-SPIRAL, BETA-BARREL, VIRAL PROTEIN
3f9e:A (VAL18) to (PRO39) CRYSTAL STRUCTURE OF THE S139A MUTANT OF SARS-CORONOVIRUS 3C-LIKE PROTEASE | PROTEASE, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
1btp:A (GLN30) to (SER54) UNIQUE BINDING OF A NOVEL SYNTHETIC INHIBITOR, N-[3-[4-[4- (AMIDINOPHENOXY)-CARBONYL]PHENYL]-2-METHYL-2-PROPENOYL]-N- ALLYLGLYCINE METHANESULFONATE TO BOVINE TRYPSIN, REVEALED BY THE CRYSTAL STRUCTURE OF THE COMPLEX | HYDROLASE (SERINE PROTEINASE)
1btw:A (GLN30) to (SER54) EPISELECTION: NOVEL KI ~NANOMOLAR INHIBITORS OF SERINE PROTEASES SELECTED BY BINDING OR CHEMISTRY ON AN ENZYME SURFACE | TRIPEPTIDEBORONATE 1,3-PROPANEDIOL MONOESTER-INHIBITED, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1o9y:C (HIS51) to (ILE77) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE HRCQB PROTEIN FROM PSEUDOMONAS SYRINGAE PV. PHASEOLICOLA | SECRETORY PROTEIN, HRP, TYPE III SECRETION SYSTEM, PHYTOPATHOGENICITY, STRUCTURAL PROTEIN
1bui:A (GLN30) to (LEU53) STRUCTURE OF THE TERNARY MICROPLASMIN-STAPHYLOKINASE-MICROPLASMIN COMPLEX: A PROTEINASE-COFACTOR-SUBSTRATE COMPLEX IN ACTION | PLASMIN, STAPHYLOKINASE, SERINE PROTEINASE, FIBRINOLYSIS, COFACTOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1bui:B (GLN30) to (THR54) STRUCTURE OF THE TERNARY MICROPLASMIN-STAPHYLOKINASE-MICROPLASMIN COMPLEX: A PROTEINASE-COFACTOR-SUBSTRATE COMPLEX IN ACTION | PLASMIN, STAPHYLOKINASE, SERINE PROTEINASE, FIBRINOLYSIS, COFACTOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1bv9:B (PRO9) to (GLU34) HIV-1 PROTEASE (I84V) COMPLEXED WITH XV638 OF DUPONT PHARMACEUTICALS | HIV-1 PROTEASE (I84V) XV638, HYDROLASE
2bu8:A (GLN333) to (PRO364) CRYSTAL STRUCTURES OF HUMAN PYRUVATE DEHYDROGENASE KINASE 2 CONTAINING PHYSIOLOGICAL AND SYNTHETIC LIGANDS | TRANSFERASE, PYRUVATE DEHYDROGENASE KINASE 2 GHKL MOTIF REGULATION
3sa4:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF72 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3sa6:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF71 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3sa8:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KB83 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3saa:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF77 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3sac:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF80 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4xa9:c (GLN121) to (PRO171) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE N-TERMINAL DOMAIN OF RAVJ AND LEGL1 FROM LEGIONELLA PNEUMOPHILA STR. PHILADELPHIA | STRUCTURAL GENOMICS, INFECTION, EFFECTOR, PAPAIN-LIKE CYSTEINE PROTEASE FAMILY, LEUCINE-RICH-REPEAT, COMPLEX, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
4xa9:g (GLN121) to (PRO171) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE N-TERMINAL DOMAIN OF RAVJ AND LEGL1 FROM LEGIONELLA PNEUMOPHILA STR. PHILADELPHIA | STRUCTURAL GENOMICS, INFECTION, EFFECTOR, PAPAIN-LIKE CYSTEINE PROTEASE FAMILY, LEUCINE-RICH-REPEAT, COMPLEX, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
4xa9:h (GLN121) to (PRO171) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE N-TERMINAL DOMAIN OF RAVJ AND LEGL1 FROM LEGIONELLA PNEUMOPHILA STR. PHILADELPHIA | STRUCTURAL GENOMICS, INFECTION, EFFECTOR, PAPAIN-LIKE CYSTEINE PROTEASE FAMILY, LEUCINE-RICH-REPEAT, COMPLEX, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
4hsi:A (VAL602) to (LEU625) GLYCOPROTEIN B FROM HERPES SIMPLEX VIRUS TYPE 1, A504P/R505G/Q507G/N511G MUTANT, LOW-PH | VIRAL FUSION PROTEIN, VIRAL ENVELOPE, VIRAL PROTEIN
3sb4:A (LYS282) to (GLY311) CRYSTAL STRUCTURE OF A LEUCINE-RICH REPEAT PROTEIN (BT_1240) FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 AT 1.99 A RESOLUTION | LRR, RIGHT-HANDED BETA-ALPHA SUPERHELIX, LEUCINE-RICH REPEAT, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, PROTEIN BINDING
4htc:H (GLN30) to (THR54) THE REFINED STRUCTURE OF THE HIRUDIN-THROMBIN COMPLEX | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, SERINE PROTEASE
2pgb:B (GLN30) to (THR54) INHIBITOR-FREE HUMAN THROMBIN MUTANT C191A-C220A | SERINE PROTEASE, HYDROLASE
2bvr:H (GLN30) to (THR54) HUMAN THROMBIN COMPLEXED WITH FRAGMENT-BASED SMALL MOLECULES OCCUPYING THE S1 POCKET | SERINE PROTEASE, COAGULATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1by2:A (ASP5) to (ASP32) STRUCTURE OF M2BP SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN | EXTRACELLULAR MODULE, SCAVENGER RECEPTOR, TUMOUR-ASSOCIATED ANTIGEN, EXTRACELLULAR MATRIX, GLYCOSYLATED PROTEIN
1odw:B (VAL11) to (GLU34) NATIVE HIV-1 PROTEINASE | PROTEINASE, RETROPEPSIN, RETROVIRUS, HIV, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1bzx:E (GLN30) to (SER54) THE CRYSTAL STRUCTURE OF ANIONIC SALMON TRYPSIN IN COMPLEX WITH BOVINE PANCREATIC TRYPSIN INHIBITOR | TRYPSIN, SERINE PROTEINASES, COLD ADAPTATION, INHIBITOR, SUBSTRATE SPECIFICITY, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1c2d:A (GLN30) to (SER54) RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES | ZN(II)-MEDIATED SERINE PROTEASE INHIBITORS, PH DEPENDENCE, ZN(II) AFFINITY STUCTURE-BASED DRUG DESIGN, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
2pme:A (VAL222) to (LEU242) THE APO CRYSTAL STRUCTURE OF THE GLYCYL-TRNA SYNTHETASE | CLASSIIA AMINOACYL TRNA SYNTHETASE, LIGASE
2pmf:A (VAL222) to (LEU242) THE CRYSTAL STRUCTURE OF A HUMAN GLYCYL-TRNA SYNTHETASE MUTANT | CLASSIIA AMINOACYL-TRNA SYNTHETASE, LIGASE
4hyy:A (THR298) to (THR331) FILAMENT OF OCTAMERIC RINGS OF DMC1 RECOMBINASE FROM HOMO SAPIENS | RECA HOMOLOG, DNA STRAND EXCHANGE, DNA, NUCLEUS, RECOMBINATION
4xe9:A (GLY361) to (ARG386) CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH OPTACTIN | HYDROLASE, INTRAMOLECULAR TRANS-SIALIDASE, GLYCOSIDASE, DRUG DESIGN, NEURAMINIDASE, ALLOSTERIC INHIBITOR, SERENDIPITOUS ALLOSTERIC SITES, CRYSTALLIZATION ARTEFACTS
2bza:A (GLN30) to (SER54) BOVINE PANCREAS BETA-TRYPSIN IN COMPLEX WITH BENZYLAMINE | HYDROLASE (SERINE PROTEINASE)
4xey:B (ASP260) to (THR291) CRYSTAL STRUCTURE OF AN SH2-KINASE DOMAIN CONSTRUCT OF C-ABL TYROSINE KINASE | TYROSINE KINASE, KINASE DOMAIN, SH2 DOMAIN, DASATINIB, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4xf0:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE VARIANT - C93A AT PH 8.0 WITH CYSTEINE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, CYTOSOL, THIOL DIOXYGENASE, OXIDOREDUCTASE
4xf1:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE VARIANT - Y157F AT PH 8.0 WITH CYSTEINE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, CYTOSOL, THIOL DIOXYGENASE, OXIDOREDUCTASE
4xf4:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE AT PH 8.0 IN COMPLEX WITH HOMOCYSTEINE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, THIOL DIOXYGENASE, OXIDOREDUCTASE
4xf9:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE VARIANT - C93A AT PH 8.0 IN COMPLEX WITH HOMOCYSTEINE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, THIOL DIOXYGENASE, OXIDOREDUCTASE
4xfc:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE VARIANT - Y157F AT PH 6.2 UNLIGANDED | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, THIOL DIOXYGENASE, OXIDOREDUCTASE
4xfb:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE VARIANT - C93A AT PH 8.0 UNLIGANDED | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, THIOL DIOXYGENASE, OXIDOREDUCTASE
4xff:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE VARIANT - Y157F AT PH 6.2 WITH DITHIONITE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, THIOL DIOXYGENASE, OXIDOREDUCTASE
4xfi:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE VARIANT - Y157F AT PH 6.2 WITH HOMOCYSTEINE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, THIOL DIOXYGENASE, OXIDOREDUCTASE
1c4y:2 (GLN30) to (THR54) SELECTIVE NON-ELECTROPHILIC THROMBIN INHIBITORS | COMPLEX (SERINE PROTEASE-INHIBITOR), HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1c5n:H (GLN30) to (THR54) STRUCTURAL BASIS FOR SELECTIVITY OF A SMALL MOLECULE, S1-BINDING, SUB- MICROMOLAR INHIBITOR OF UROKINASE TYPE PLASMINOGEN ACTIVATOR | S1 SITE INHIBITOR, UROKINASE, TRYPSIN, BLOOD CLOTTING, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4i1e:A (SER313) to (TYR359) CRYSTAL STRUCTURE OF RABBIT RYANODINE RECEPTOR 1 (RESIDUES 1-536) DISEASE MUTANT G249R | CALCIUM CHANNEL, ER/SR MEMBRANE, METAL TRANSPORT
3sfj:A (PHE32) to (GLN80) CRYSTAL STRUCTURE OF TAX-INTERACTING PROTEIN-1 (TIP-1) PDZ DOMAIN BOUND TO ICAL36 INHIBITOR PEPTIDE | PDZ:PEPTIDE COMPLEX, SIGNALING PROTEIN-INHIBITOR COMPLEX
3sfj:C (PHE32) to (GLN80) CRYSTAL STRUCTURE OF TAX-INTERACTING PROTEIN-1 (TIP-1) PDZ DOMAIN BOUND TO ICAL36 INHIBITOR PEPTIDE | PDZ:PEPTIDE COMPLEX, SIGNALING PROTEIN-INHIBITOR COMPLEX
3sga:E (GLU29) to (ALA55) STRUCTURES OF PRODUCT AND INHIBITOR COMPLEXES OF STREPTOMYCES GRISEUS PROTEASE A AT 1.8 ANGSTROMS RESOLUTION. A MODEL FOR SERINE PROTEASE CATALYSIS | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, SERINE PROTEINASE
3sgz:A (THR59) to (PRO76) HIGH RESOLUTION CRYSTAL STRUCTURE OF RAT LONG CHAIN HYDROXY ACID OXIDASE IN COMPLEX WITH THE INHIBITOR 4-CARBOXY-5-[(4-CHIOROPHENYL) SULFANYL]-1, 2, 3-THIADIAZOLE. | FLAVOPROTEIN, HOMOLOGY, LONG CHAIN HYDROXY ACID OXIDASE, INHIBITOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3sgz:C (THR59) to (PRO76) HIGH RESOLUTION CRYSTAL STRUCTURE OF RAT LONG CHAIN HYDROXY ACID OXIDASE IN COMPLEX WITH THE INHIBITOR 4-CARBOXY-5-[(4-CHIOROPHENYL) SULFANYL]-1, 2, 3-THIADIAZOLE. | FLAVOPROTEIN, HOMOLOGY, LONG CHAIN HYDROXY ACID OXIDASE, INHIBITOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3sha:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH UBTHR97 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, THROMBIN INHIBITOR, GLYCOSYLATION, BLOOD, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3shc:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH UBTHR101 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, THROMBIN INHIBITOR, GLYCOSYLATION, BLOOD, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3fiv:A (GLY52) to (ASP94) CRYSTAL STRUCTURE OF FELINE IMMUNODEFICIENCY VIRUS PROTEASE COMPLEXED WITH A SUBSTRATE | ASPARTIC PROTEASE, RETROVIRAL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3fiv:B (GLY52) to (ASP94) CRYSTAL STRUCTURE OF FELINE IMMUNODEFICIENCY VIRUS PROTEASE COMPLEXED WITH A SUBSTRATE | ASPARTIC PROTEASE, RETROVIRAL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2ppd:C (LYS240) to (TRP265) OXIDIZED H145A MUTANT OF AFNIR BOUND TO NITRIC OXIDE | H145A, NITRITE REDUCTASE, NITRIC OXIDE, DENITRIFICATION, BACTERIA, OXIDOREDUCTASE
4i3j:A (PHE92) to (ARG124) STRUCTURES OF PR1 INTERMEDIATE OF PHOTOACTIVE YELLOW PRTEIN E46Q MUNTANT FROM TIME-RESOLVED LAUE CRYSTALLOGRAPHY COLLECTED AT 14ID APS | PHOTORECEPTOR, CHROMOPHORE, PHOTORECEPTOR PROTEIN, RECEPTOR, SENSORY TRANSDUCTION, LUMINESCENT PROTEIN
3fk9:B (GLN2) to (ALA28) CRYSTAL STRUCTURE OF MMUTATOR MUTT PROTEIN FROM BACILLUS HALODURANS | STRUCTURAL GENOMICS, HYDROLASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
2pqe:A (ALA12) to (LEU36) SOLUTION STRUCTURE OF PROLINE-FREE MUTANT OF STAPHYLOCOCCAL NUCLEASE | BETA BARREL, OB FOLD, HYDROLASE
2pqf:C (ARG636) to (PHE664) HUMAN POLY(ADP-RIBOSE) POLYMERASE 12, CATALYTIC FRAGMENT IN COMPLEX WITH AN INHIBITOR 3-AMINOBENZOIC ACID | ENZYME-INHIBITOR COMPLEX, CATALYTIC FRAGMENT, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
2pqf:E (PRO637) to (PHE664) HUMAN POLY(ADP-RIBOSE) POLYMERASE 12, CATALYTIC FRAGMENT IN COMPLEX WITH AN INHIBITOR 3-AMINOBENZOIC ACID | ENZYME-INHIBITOR COMPLEX, CATALYTIC FRAGMENT, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
4xil:A (GLY361) to (VAL385) CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH OPTACTIN AT PH 7.4 IN PBS WITH MPD AS THE CRYOPROTECTANT | HYDROLASE, INTRAMOLECULAR TRANS-SIALIDASE, GLYCOSIDASE, DRUG DESIGN, NEURAMINIDASE, ALLOSTERIC INHIBITOR, SERENDIPITOUS ALLOSTERIC SITES, CRYSTALLIZATION ARTEFACTS
4xik:A (GLY361) to (VAL385) CRYSTAL STRUCTURE OF NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH DMSO | HYDROLASE, INTRAMOLECULAR TRANS-SIALIDASE, GLYCOSIDASE, DRUG DESIGN, NEURAMINIDASE, ALLOSTERIC INHIBITOR, SERENDIPITOUS ALLOSTERIC SITES, CRYSTALLIZATION ARTEFACTS
1cbg:A (THR459) to (LEU479) THE CRYSTAL STRUCTURE OF A CYANOGENIC BETA-GLUCOSIDASE FROM WHITE CLOVER (TRIFOLIUM REPENS L.), A FAMILY 1 GLYCOSYL-HYDROLASE | CYANOGENIC BETA-GLUCOSIDASE, HYDROLASE (O-GLYCOSYL)
4xio:A (GLY361) to (VAL385) CRYSTAL STRUCTURE OF APO NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE AT PH 8.0 WITH MPD AS THE CRYOPROTECTANT | HYDROLASE, INTRAMOLECULAR TRANS-SIALIDASE, GLYCOSIDASE, DRUG DESIGN, NEURAMINIDASE, ALLOSTERIC INHIBITOR, SERENDIPITOUS ALLOSTERIC SITES, CRYSTALLIZATION ARTEFACTS
2prf:A (GLY59) to (LYS81) THREE DIMENSIONAL SOLUTION STRUCTURE OF ACANTHAMOEBA PROFILIN I | ACTIN-BINDING
3si4:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH UBTHR104 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, BLOOD CLOTTING INHIBITOR, THROMBIN INHIBITOR, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3fkt:A (GLY33) to (GLY61) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE COMPLEXED WITH SPIROPIPERDINE IMINOHYDANTOIN INHIBITOR | ASPARTYL PROTEASE, BACE, ALTERNATIVE SPLICING, GLYCOPROTEIN, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
2psy:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN KALLIKREIN 5 IN COMPLEX WITH LEUPEPTIN AND ZINC | ZINC INHIBITION, STRATUM CORNEUM, GLCOSYLATION, HYDROLASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
1ol2:A (ASN3) to (ARG36) CYCLIN A BINDING GROOVE INHIBITOR H-ARG-ARG-LEU-ASN-(P-F-PHE)-NH2 | CELL CYCLE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, CYCLIN A, LIGAND EXCHANGE, PEPTIDOMIMETICS, KINASE
1ol6:A (GLU134) to (PHE165) STRUCTURE OF UNPHOSPHORYLATED D274N MUTANT OF AURORA-A | TRANSFERASE, CELL CYCLE, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, PHOSPHORYLATION
4xjz:A (GLY361) to (ARG386) CRYSTAL STRUCTURE OF APO NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE AT PH 7.4 IN PBS WITH DMSO | HYDROLASE, INTRAMOLECULAR TRANS-SIALIDASE, GLYCOSIDASE, DRUG DESIGN, NEURAMINIDASE, ALLOSTERIC INHIBITOR, SERENDIPITOUS ALLOSTERIC SITES, CRYSTALLIZATION ARTEFACTS
4xkv:A (ALA675) to (ARG707) TAILSPIKE PROTEIN MUTANT D339N OF E. COLI BACTERIOPHAGE HK620 | BETA HELIX, PROTEIN-CARBOHYDRATE COMPLEX, PECTIN LYASE FOLD, METAL BINDING PROTEIN, VIRAL PROTEIN
2pvz:B (LEU201) to (ASN228) CRYSTAL STRUCTURE OF METHYLACONITATE ISOMERASE PRPF FROM SHEWANELLA ONEIDENSIS | PROPIONATE CATABOLISM, DIAMINOPIMELATE EPIMERASE LIKE, ACONITATE BINDING, UNKNOWN FUNCTION
1cgh:A (TYR29) to (THR54) HUMAN CATHEPSIN G | INFLAMMATION, SPECIFICITY, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4xl9:A (ALA675) to (ARG707) TAILSPIKE PROTEIN MUTANT D339A OF E. COLI BACTERIOPHAGE HK620 | BETA HELIX, PROTEIN-CARBOHYDRATE COMPLEX, PECTIN LYASE FOLD, VIRAL PROTEIN
3fnr:A (GLY261) to (ILE285) CRYSTAL STRUCTURE OF PUTATIVE ARGINYL T-RNA SYNTHETASE FROM CAMPYLOBACTER JEJUNI; | ARGINYL T-RNA SYNTHETASE, TRANSFERASE, PSI-2, NYSGXRC, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, AMINOACYL-TRNA SYNTHETASE, ATP-BINDING, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS
1op8:A (TYR29) to (THR54) CRYSTAL STRUCTURE OF HUMAN GRANZYME A | GRANZYME A, SERINE PROTEINASE, APOPTOSIS, HYDROLASE
1op8:D (TYR29) to (THR54) CRYSTAL STRUCTURE OF HUMAN GRANZYME A | GRANZYME A, SERINE PROTEINASE, APOPTOSIS, HYDROLASE
1op8:F (TYR29) to (THR54) CRYSTAL STRUCTURE OF HUMAN GRANZYME A | GRANZYME A, SERINE PROTEINASE, APOPTOSIS, HYDROLASE
2c47:B (PRO44) to (PRO78) STRUCTURE OF CASEIN KINASE 1 GAMMA 2 | SERINE/THREONINE KINASE, ACTIN CYTOSKELETON ORGANISATION, ATP-BINDING, TRANSFERASE, WNT SIGNALING PATHWAY
2c47:C (PHE46) to (PRO78) STRUCTURE OF CASEIN KINASE 1 GAMMA 2 | SERINE/THREONINE KINASE, ACTIN CYTOSKELETON ORGANISATION, ATP-BINDING, TRANSFERASE, WNT SIGNALING PATHWAY
2c47:D (PHE46) to (PRO78) STRUCTURE OF CASEIN KINASE 1 GAMMA 2 | SERINE/THREONINE KINASE, ACTIN CYTOSKELETON ORGANISATION, ATP-BINDING, TRANSFERASE, WNT SIGNALING PATHWAY
3fog:A (HIS2) to (TYR37) CRYSTAL STRUCTURE OF THE PX DOMAIN OF SORTING NEXIN-17 (SNX17) | HELIX, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, CYTOPLASM, ENDOSOME, PHOSPHOPROTEIN, PROTEIN TRANSPORT, TRANSPORT
2c4i:A (PRO7) to (THR40) CRYSTAL STRUCTURE OF ENGINEERED AVIDIN | BIOTIN, GLYCOPROTEIN, SIGNALOR
4i7i:A (GLU19) to (PRO51) CRYSTAL STRUCTURE OF RABBIT RYANODINE RECEPTOR 1 (RESIDUES 1-536) DISEASE MUTANT L14R | CALCIUM CHANNEL, SR/ER MEMBRANE, METAL TRANSPORT
3fou:A (GLY55) to (SER96) LOW PH STRUCTURE OF THE RIESKE PROTEIN FROM THERMUS THERMOPHILUS AT 2.1 A | RIESKE PROTEIN, PR, [2FE-2S], ELECTRON TRANSPORT
3fou:B (GLY55) to (SER96) LOW PH STRUCTURE OF THE RIESKE PROTEIN FROM THERMUS THERMOPHILUS AT 2.1 A | RIESKE PROTEIN, PR, [2FE-2S], ELECTRON TRANSPORT
4i7y:H (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN ALPHA THROMBIN IN COMPLEX WITH A 27-MER APTAMER BOUND TO EXOSITE II | PROTEIN-DNA COMPLEX, SERINE PROTEASE, BLOOD COAGULATION, APTAMER, HYDROLASE-HYDROLASE INHIBITOR-DNA COMPLEX, SERINE PROTEASE FOLD, DNA APTAMER, BLOOD, G-QUADRUPLEX, DUPLEX-QUADRUPLEX JUNCTION
4i7z:C (ASP100) to (PRO130) CRYSTAL STRUCTURE OF CYTOCHROME B6F IN DOPG, WITH DISORDERED RIESKE IRON-SULFUR PROTEIN SOLUBLE DOMAIN | CYTOCHROME, MEMBRANE PROTEIN, PLASTOQUINOL:PLASTOCYANIN OXIDOREDUCTASE, PLASTOCYANIN, THYLAKOID MEMBRANE, PHOTOSYNTHESIS
4i86:B (GLY49) to (ASN86) CRYSTAL STRUCTURE OF PILZ DOMAIN OF CESA FROM CELLULOSE SYNTHESIZING BACTERIUM | BETA-BARREL FOLD, C-DI-GMP BINDING, TRANSFERASE
2pyt:A (VAL139) to (PRO166) CRYSTAL STRUCTURE OF A PUTATIVE ETHANOLAMINE UTILIZATION PROTEIN Q (EUTQ, STM2468) FROM SALMONELLA TYPHIMURIUM LT2 AT 1.90 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
2pyt:B (VAL139) to (PRO166) CRYSTAL STRUCTURE OF A PUTATIVE ETHANOLAMINE UTILIZATION PROTEIN Q (EUTQ, STM2468) FROM SALMONELLA TYPHIMURIUM LT2 AT 1.90 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
1orf:A (VAL31) to (THR54) THE OLIGOMERIC STRUCTURE OF HUMAN GRANZYME A REVEALS THE MOLECULAR DETERMINANTS OF SUBSTRATE SPECIFICITY | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3soe:A (PHE615) to (GLU646) CRYSTAL STRUCTURE OF THE 3RD PDZ DOMAIN OF THE HUMAN MEMBRANE- ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 3 (MAGI3) | STRUCTURAL GENOMICS CONSORTIUM, SGC, PDZ DOMAIN, SIGNALING PROTEIN
3son:A (ARG2) to (PHE34) CRYSTAL STRUCTURE OF A PUTATIVEL NUDIX HYDROLASE (LMOF2365_2679) FROM LISTERIA MONOCYTOGENES STR. 4B F2365 AT 1.70 A RESOLUTION | NUDIX, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, HYDROLASE
3son:B (PHE5) to (PHE34) CRYSTAL STRUCTURE OF A PUTATIVEL NUDIX HYDROLASE (LMOF2365_2679) FROM LISTERIA MONOCYTOGENES STR. 4B F2365 AT 1.70 A RESOLUTION | NUDIX, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, HYDROLASE
2pzy:A (TYR63) to (GLN96) STRUCTURE OF MK2 COMPLEXED WITH COMPOUND 76 | MK2, PROTEIN KINASE, TRANSFERASE
3sov:A (PRO21) to (VAL46) THE STRUCTURE OF A BETA PROPELLER DOMAIN IN COMPLEX WITH PEPTIDE S | BETA PROPELLER, PROTEIN BINDING-ANTAGONIST COMPLEX
3frn:A (VAL258) to (GLU283) CRYSTAL STRUCTURE OF FLAGELLAR PROTEIN FLGA FROM THERMOTOGA MARITIMA MSB8 | STRUCTURAL GENOMICS, PERIPLASMIC, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, FLAGELLUM, UNKNOWN FUNCTION
1cr4:A (LEU513) to (PRO544) CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE 4 PROTEIN OF BACTERIOPHAGE T7: COMPLEX WITH DTDP | RECA-TYPE PROTEIN FOLD, TRANSFERASE
4ic5:A (VAL103) to (THR144) CRYSTAL STRUCTURE OF DEG5 | BETS-BARREL, ENDOPEPTIDASE, CALCIUM BINDING, CHLOROPLAST, HYDROLASE
4ic5:A (PRO269) to (ILE300) CRYSTAL STRUCTURE OF DEG5 | BETS-BARREL, ENDOPEPTIDASE, CALCIUM BINDING, CHLOROPLAST, HYDROLASE
4ic5:B (PRO269) to (ILE300) CRYSTAL STRUCTURE OF DEG5 | BETS-BARREL, ENDOPEPTIDASE, CALCIUM BINDING, CHLOROPLAST, HYDROLASE
4ic5:C (PRO269) to (ILE300) CRYSTAL STRUCTURE OF DEG5 | BETS-BARREL, ENDOPEPTIDASE, CALCIUM BINDING, CHLOROPLAST, HYDROLASE
4ic6:A (ARG189) to (LYS219) CRYSTAL STRUCTURE OF DEG8 | BETA-BARREL, HYDROLASE
4ic7:A (GLU54) to (ILE86) CRYSTAL STRUCTURE OF THE ERK5 KINASE DOMAIN IN COMPLEX WITH AN MKK5 BINDING FRAGMENT | KINASE DOMAIN, SIGNALING PROTEIN COMPLEX, TRANSFERASE
4ick:A (ARG4) to (PRO40) CRYSTAL STRUCTURE OF HUMAN AP4A HYDROLASE E58A MUTANT | NUDIX FOLD, HYDROLASE
1ovz:B (GLY103) to (LYS139) CRYSTAL STRUCTURE OF HUMAN FCARI | FCARI, CD89, IGA, FC RECEPTOR, IMMUNOGLOBULIN-LIKE DOMAIN, IMMUNE SYSTEM
1owb:A (ALA5) to (ASP30) THREE DIMENSIONAL STRUCTURE ANALYSIS OF THE VARIANT R109L NADH COMPLEX OF TYPE II CITRATE SYNTHASE FROM E. COLI | ALLOSTERY, NADH, TYPE II CITRATE SYNTHASE, E. COLI, R109L, TRANSFERASE
4idv:A (TRP399) to (ARG432) CRYSTAL STRUCTURE OF NIK WITH COMPOUND 4-{3-[2-AMINO-5-(2- METHOXYETHOXY)PYRIMIDIN-4-YL]-1H-INDOL-5-YL}-2-METHYLBUT-3-YN-2-OL (13V) | NIK, NUCLEAR FACTOR (NF)-KB, P100 PROCESSING, 2-AMINOPYRIMIDINE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4idv:B (TRP399) to (ARG432) CRYSTAL STRUCTURE OF NIK WITH COMPOUND 4-{3-[2-AMINO-5-(2- METHOXYETHOXY)PYRIMIDIN-4-YL]-1H-INDOL-5-YL}-2-METHYLBUT-3-YN-2-OL (13V) | NIK, NUCLEAR FACTOR (NF)-KB, P100 PROCESSING, 2-AMINOPYRIMIDINE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4idz:A (SER95) to (PRO119) CRYSTAL STRUCTURE OF THE HUMAN FAT MASS AND OBESITY ASSOCIATED PROTEIN (FTO) IN COMPLEX WITH N-OXALYLGLYCINE (NOG) | DOUBLE-STRANDED BETA HELIX, JELLY-ROLL MOTIF, OXIDOREDUCTASE, DIOXYGENASE, NUCLEIC ACID DEMETHYLASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
2q4s:A (ARG57) to (SER84) ENSEMBLE REFINEMENT OF THE PROTEIN CRYSTAL STRUCTURE OF CYSTEINE DIOXYGENASE TYPE I FROM MUS MUSCULUS MM.241056 | ENSEMBLE REFINEMENT, REFINEMENT METHODOLOGY DEVELOPMENT, MM.241056, PFAM05995.2 CDO_I, BC013638, CUPIN FAMILY, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS, CESG, OXIDOREDUCTASE
2q54:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF KB73 BOUND TO HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2q55:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF KK44 BOUND TO HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITOR, HYDROLASE
4ieo:A (ARG57) to (SER84) UNLIGANDED CYSTEINE DIOXYGENASE AT PH 4.0 IN THE PRESENCE OF CYS | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
4iep:A (ARG57) to (SER84) UNLIGANDED CYSTEINE DIOXYGENASE AT PH 4.5 IN THE PRESENCE OF CYS | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
4ieq:A (ARG57) to (SER84) UNLIGANDED CYSTEINE DIOXYGENASE AT PH 5.0 IN THE PRESENCE OF CYS | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
4ier:A (ARG57) to (SER84) CYS-PERSULFENATE BOUND CYSTEINE DIOXYGENASE AT PH 5.5 IN THE PRESENCE OF CYS | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
4ies:A (ARG57) to (SER84) CYS-PERSULFENATE BOUND CYSTEINE DIOXYGENASE AT PH 6.2 IN THE PRESENCE OF CYS | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
4iet:A (ARG57) to (SER84) CYS-PERSULFENATE BOUND CYSTEINE DIOXYGENASE AT PH 6.8 IN THE PRESENCE OF CYS | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
4ieu:A (ARG57) to (SER84) CYS-PERSULFENATE BOUND CYSTEINE DIOXYGENASE AT PH 7.0 IN THE PRESENCE OF CYS | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
4iev:A (ARG57) to (SER84) CYS-ONLY BOUND CYSTEINE DIOXYGENASE AT PH 8.0 IN THE PRESENCE OF CYS | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
4iew:A (ARG57) to (SER84) CYS-ONLY BOUND CYSTEINE DIOXYGENASE AT PH 9.0 IN THE PRESENCE OF CYS | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
4iex:A (ARG57) to (SER84) UNLIGANDED ROOM-TEMP CYSTEINE DIOXYGENASE AT PH 6.2 | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
4iey:A (ARG57) to (SER84) CYS-PERSULFENATE BOUND CYSTEINE DIOXYGENASE AT PH 7.0 IN THE PRESENCE OF CYS, HOME-SOURCE STRUCTURE | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
4iez:A (ARG57) to (SER84) UNLIGANDED CYSTEINE DIOXYGENASE AT PH 8.0 | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
2q5i:A (VAL222) to (LEU242) CRYSTAL STRUCTURE OF APO S581L GLYCYL-TRNA SYNTHETASE MUTANT | AMINOACYL-TRNA SYNTHETASE, ATP-BINDING, STRUCTURAL GENOMICS, GLYCYL- TRNA SYNTHETASE, OXFORD PROTEIN PRODUCTION FACILITY, OPPF, LIGASE
2q5k:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF LOPINAVIR BOUND TO WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
4xls:M (GLY22) to (PRO50) CRYSTAL STRUCTURE OF T. AQUATICUS TRANSCRIPTION INITIATION COMPLEX WITH CARD CONTAINING UPSTREAM FORK PROMOTER. | PROTEIN-DNA COMPLEX, BACTERIAL TRANSCRIPTION INITIATION COMPLEX, TRANSCRIPTION
1oyt:H (GLN30) to (THR54) COMPLEX OF RECOMBINANT HUMAN THROMBIN WITH A DESIGNED FLUORINATED INHIBITOR | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4xma:A (GLY361) to (ARG386) CRYSTAL STRUCTURE OF THE K499G MUTANT OF NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH OPTACTIN | HYDROLASE, INTRAMOLECULAR TRANS-SIALIDASE, GLYCOSIDASE, DRUG DESIGN, NEURAMINIDASE, ALLOSTERIC INHIBITOR, SERENDIPITOUS ALLOSTERIC SITES, CRYSTALLIZATION ARTEFACTS
3sti:C (LYS89) to (ASN120) CRYSTAL STRUCTURE OF THE PROTEASE DOMAIN OF DEGQ FROM ESCHERICHIA COLI | SERINE PROTEASE, PDZ DOMAIN, PROTEASE, CHAPERONE, HYDROLASE
4xmi:A (GLY361) to (ARG386) CRYSTAL STRUCTURE OF THE K499G MUTANT OF NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE | HYDROLASE, INTRAMOLECULAR TRANS-SIALIDASE, GLYCOSIDASE, DRUG DESIGN, NEURAMINIDASE, ALLOSTERIC INHIBITOR, SERENDIPITOUS ALLOSTERIC SITES, CRYSTALLIZATION ARTEFACTS
4ig2:A (TRP31) to (GLN55) 1.80 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF R51A AND R239A HETERODIMER 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE FROM PSEUDOMONAS FLUORESCENS | TIM-BARREL, DECARBOXYLASE, METAL-BINDING, LYASE
1p06:A (ILE29) to (ALA55) STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1p09:A (ILE29) to (ALA55) STRUCTURAL PLASTICITY AS A DETERMINANT OF ENZYME SPECIFICITY. CREATING BROADLY SPECIFIC PROTEASES | HYDROLASE (SERINE PROTEINASE)
3fxy:D (GLN316) to (VAL339) ACIDIC MAMMALIAN CHINASE, CATALYTIC DOMAIN | CHITINASE, STRUCTURE, CRYSTALLOGRAPHY, ASTHMA, CHITIN DEGRADATION, ALTERNATIVE SPLICING, CARBOHYDRATE METABOLISM, CHITIN-BINDING, CYTOPLASM, GLYCOSIDASE, HYDROLASE, POLYMORPHISM, POLYSACCHARIDE DEGRADATION, SECRETED
3fy1:A (GLN316) to (VAL339) THE ACIDIC MAMMALIAN CHITINASE CATALYTIC DOMAIN IN COMPLEX WITH METHYLALLOSAMIDIN | CHITINASE, STRUCTURE, CRYSTALLOGRAPHY, ASTHMA,INHIBITOR, CHITIN DEGRADATION, METHYLALLOSAMIDIN, ALTERNATIVE SPLICING, CARBOHYDRATE METABOLISM, CHITIN-BINDING, CYTOPLASM, GLYCOSIDASE, HYDROLASE, POLYMORPHISM, POLYSACCHARIDE DEGRADATION, SECRETED
3fy1:B (GLN316) to (VAL339) THE ACIDIC MAMMALIAN CHITINASE CATALYTIC DOMAIN IN COMPLEX WITH METHYLALLOSAMIDIN | CHITINASE, STRUCTURE, CRYSTALLOGRAPHY, ASTHMA,INHIBITOR, CHITIN DEGRADATION, METHYLALLOSAMIDIN, ALTERNATIVE SPLICING, CARBOHYDRATE METABOLISM, CHITIN-BINDING, CYTOPLASM, GLYCOSIDASE, HYDROLASE, POLYMORPHISM, POLYSACCHARIDE DEGRADATION, SECRETED
3sv2:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH UBTHR105 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, HIRUDIN, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3sw2:B (GLN30) to (THR54) X-RAY CRYSTAL STRUCTURE OF HUMAN FXA IN COMPLEX WITH 6-CHLORO-N-((3S)- 2-OXO-1-(2-OXO-2-((5S)-8-OXO-5,6-DIHYDRO-1H-1,5-METHANOPYRIDO[1,2- A][1,5]DIAZOCIN-3(2H,4H,8H)-YL)ETHYL)PIPERIDIN-3-YL)NAPHTHALENE-2- SULFONAMIDE | SERINE PROTEASE, EPIDERMAL GROWTH FACTOR-LIKE DOMAIN, BLOOD COAGULATION FACTOR, CLEAVAGE ON PAIR OF BASIC RESIDUES, EGF-LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROXYLATION, ZYMOGEN, HYDROLASE, BLOOD CLOTTING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2cci:C (ASN3) to (THR39) CRYSTAL STRUCTURE OF PHOSPHO-CDK2 CYCLIN A IN COMPLEX WITH A PEPTIDE CONTAINING BOTH THE SUBSTRATE AND RECRUITMENT SITES OF CDC6 | COMPLEX (TRANSFERASE/CELL DIVISION), PROTEIN KINASES, CELL CYCLE, RECRUITMENT, SUBSTRATE RECOGNITION, ATP-BINDING, CELL DIVISION, KINASE, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHORYLATION, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE, CYCLIN, DNA REPLICATION, NUCLEAR PROTEIN, COMPLEX
2q8h:A (GLN370) to (PRO401) STRUCTURE OF PYRUVATE DEHYDROGENASE KINASE ISOFORM 1 IN COMPLEX WITH DICHLOROACETATE (DCA) | GHKL ATPASE/KINASE FAMILY, PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL KINASE, DICHROLOACETATE, TRANSFERASE
3fzz:A (ALA36) to (ALA63) STRUCTURE OF GRC | HYDROLASE, CYTOLYSIS, PROTEASE, SERINE PROTEASE, ZYMOGEN
3fzz:B (ALA36) to (ALA63) STRUCTURE OF GRC | HYDROLASE, CYTOLYSIS, PROTEASE, SERINE PROTEASE, ZYMOGEN
1p3c:A (TYR24) to (THR44) GLUTAMYL ENDOPEPTIDASE FROM BACILLUS INTERMEDIUS | SERINE PROTEASE, HYDROLASE
1p3c:A (GLY172) to (PRO199) GLUTAMYL ENDOPEPTIDASE FROM BACILLUS INTERMEDIUS | SERINE PROTEASE, HYDROLASE
1p3e:A (TYR24) to (THR44) STRUCTURE OF GLU ENDOPEPTIDASE IN COMPLEX WITH MPD | SERINE PROTEASE, GLU SPECIFIC, HYDROLASE
1p3e:A (GLY172) to (PRO199) STRUCTURE OF GLU ENDOPEPTIDASE IN COMPLEX WITH MPD | SERINE PROTEASE, GLU SPECIFIC, HYDROLASE
3sxs:A (GLU416) to (LYS448) CRYSTAL STRUCTURE OF BMX NON-RECEPTOR TYROSINE KINASE COMPLEXED WITH PP2 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2qbw:A (PHE6) to (GLN49) THE CRYSTAL STRUCTURE OF PDZ-FIBRONECTIN FUSION PROTEIN | FIBRONECTIN PDZ, UNKNOWN FUNCTION
2qbx:A (ARG93) to (ALA151) EPHB2/SNEW ANTAGONISTIC PEPTIDE COMPLEX | RECEPTOR TYROSINE KINASE, BI-DIRECTIONAL SIGNALING, TUMORIGENESIS, ANGIOGENESIS, SIGNALING PROTEIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, ACCELERATED TECHNOLOGIES CENTER FOR GENE TO 3D STRUCTURE, ATCG3D
1p57:B (GLN30) to (LEU53) EXTRACELLULAR DOMAIN OF HUMAN HEPSIN | SRCR, SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1d4k:A (VAL11) to (GLU34) HIV-1 PROTEASE COMPLEXED WITH A MACROCYCLIC PEPTIDOMIMETIC INHIBITOR | HIV, PROTEASE, INHIBITOR, ANTIVIRAL, STRUCTURE, HYDROLASE
2qcy:A (VAL18) to (PRO39) CRYSTAL STRUCTURE OF A MONOMERIC FORM OF SEVERE ACUTE RESPIRATORY SYNDROME (SARS) 3C-LIKE PROTEASE MUTANT | HYDROLASE, CYSTEINE PEPTIDASE, 3C-LIKE, N-FINGER, CHYMOTRYPSIN-LIKE FOLD, CATALYTIC DYAD, C-TERMINAL DOMAIN
2cga:B (GLN30) to (THR54) BOVINE CHYMOTRYPSINOGEN A. X-RAY CRYSTAL STRUCTURE ANALYSIS AND REFINEMENT OF A NEW CRYSTAL FORM AT 1.8 ANGSTROMS RESOLUTION | HYDROLASE(ZYMOGEN)
4xqf:A (ALA675) to (ARG707) TAILSPIKE PROTEIN MUTANT E372Q (DELTA D470/N471) OF E. COLI BACTERIOPHAGE HK620 | BETA HELIX, PROTEIN-CARBOHYDRATE COMPLEX, PECTIN LYASE FOLD, VIRAL PROTEIN
3sze:A (ALA365) to (GLY387) CRYSTAL STRUCTURE OF THE PASSENGER DOMAIN OF THE E. COLI AUTOTRANSPORTER ESPP | PARALLEL BETA-HELIX, SERINE PROTEASE, HYDROLASE
3sze:A (ASN490) to (THR516) CRYSTAL STRUCTURE OF THE PASSENGER DOMAIN OF THE E. COLI AUTOTRANSPORTER ESPP | PARALLEL BETA-HELIX, SERINE PROTEASE, HYDROLASE
2qf0:A (VAL154) to (ASP193) STRUCTURE OF THE DELTA PDZ TRUNCATION OF THE DEGS PROTEASE | DEGS, PROTEASE, PERIPLASMIC STRESS SENSOR, HTRA, ALLOSTERIC ACTIVATION, HYDROLASE
2qf3:A (VAL154) to (ASP193) STRUCTURE OF THE DELTA PDZ TRUNCATION OF THE DEGS PROTEASE | DEGS, PROTEASE, PERIPLASMIC STRESS SENSOR, HTRA, ALLOSTERIC ACTIVATION, HYDROLASE
4ijx:A (ARG4) to (PRO40) CRYSTAL STRUCTURE OF HUMAN AP4A HYDROLASE E58A MUTANT COMPLEXED WITH DPO | NUDIX FOLD, HYDROLASE
4ikb:B (ASP23) to (TYR60) CRYSTAL STRUCTURE OF SNX11 PX DOMAIN | SNX11, PX DOMAIN, PROTEIN TRANSPORT
2qf8:A (THR287) to (GLN310) CRYSTAL STRUCTURE OF THE COMPLEX OF BUFFALO SECRETORY GLYCOPROTEIN WITH TETRASACCHARIDE AT 2.8A RESOLUTION | COMPLEX, BUFFALO, SECRETORY, GLYCOPROTEIN, TETRASACCHARIDE, SIGNALING PROTEIN
1dce:D (ARG222) to (VAL239) CRYSTAL STRUCTURE OF RAB GERANYLGERANYLTRANSFERASE FROM RAT BRAIN | CRYSTAL STRUCTURE, RAB GERANYLGERANYLTRANSFERASE, 2.0 A RESOLUTION, N-FORMYLMETHIONINE, ALPHA SUBUNIT, BETA SUBUNIT
2qgr:A (VAL154) to (ASP193) STRUCTURE OF THE R178A MUTANT OF DELTA PDZ DEGS PROTEASE | DEGS, PROTEASE, PERIPLASMIC STRESS SENSOR, HTRA, ALLOSTERIC ACTIVATION, HYDROLASE
2qh1:B (VAL151) to (GLU178) STRUCTURE OF TA289, A CBS-RUBREDOXIN-LIKE PROTEIN, IN ITS FE+2-BOUND STATE | CBS-RUBREDOXIN-LIKE PROTEIN, FE+2, HYPOTHETICAL PROTEIN, UNKNOWN FUNCTION, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG
4xrp:F (ASP420) to (ARG435) STRUCTURE OF THE PNKP1/RNL/HEN1 RNA REPAIR COMPLEX | RNA REPAIR, KINASE, PHOSPHATASE, METHYLTRANSFERASE, LIGASE, PROTEIN BINDING
2qhz:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-1-AC87 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2qi1:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-1-KK81 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
1de3:A (TYR93) to (HIS137) SOLUTION STRUCTURE OF THE CYTOTOXIC RIBONUCLEASE ALPHA- SARCIN | ALPHA-BETA PROTEIN, HYDROLASE
2qi3:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-2-AD94 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2qi7:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-2-AD86 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
1de7:K (GLN30) to (LEU53) INTERACTION OF FACTOR XIII ACTIVATION PEPTIDE WITH ALPHA-THROMBIN: CRYSTAL STRUCTURE OF THE ENZYME-SUBSTRATE COMPLEX | ENZYME-SUBSTRATE COMPLEX, ALPHA-THROMBIN, FACTOR XIII ACTIVATION PEPTIDE, HYDROLASE/PEPTIDE, BLOOD CLOTTING, HYDROLASE-HYDROLASE SUBSTRATE COMPLEX
2ckz:B (GLU117) to (PHE140) X-RAY STRUCTURE OF RNA POLYMERASE III SUBCOMPLEX C17-C25. | DNA-DIRECTED RNA POLYMERASE, MULTIPROTEIN COMPLEX, NUCLEOTIDYLTRANSFERASE, NUCLEAR PROTEIN, HYPOTHETICAL PROTEIN, EUKARYOTIC NUCLEIC ACID POLYMERASE, CLASS III GENE TRANSCRIPTION, TRANSFERASE, TRANSCRIPTION, TRNA SYNTHESIS
4ink:A (VAL18) to (ILE35) CRYSTAL STRUCTURE OF SPLD PROTEASE FROM STAPHYLOCOCCUS AUREUS AT 1.56 A RESOLUTION | CHYMOTRYPSIN-LIKE PROTEASE, SERINE ENDOPEPTIDASE, EXTRACELLULAR STAPHYLOCOCCAL PROTEASES, HYDROLASE
4inl:A (VAL18) to (ILE35) CRYSTAL STRUCTURE OF SPLD PROTEASE FROM STAPHYLOCOCCUS AUREUS AT 2.1 A RESOLUTION | CHYMOTRYPSIN-LIKE PROTEASE, SERINE ENDOPEPTIDASE, EXTRACELLULAR STAPHYLOCOCCAL PROTEASES, HYDROLASE
2qkm:B (ILE96) to (PHE125) THE CRYSTAL STRUCTURE OF FISSION YEAST MRNA DECAPPING ENZYME DCP1-DCP2 COMPLEX | PROTEIN-PROTEIN COMPLEX, HYDROLASE
3t1e:B (THR183) to (LEU223) THE STRUCTURE OF THE NEWCASTLE DISEASE VIRUS HEMAGGLUTININ- NEURAMINIDASE (HN) ECTODOMAIN REVEALS A 4-HELIX BUNDLE STALK | BETA-PROPELLER, 4 HELIX BUNDLE, HEMAGGLUTININ, NEURAMINIDASE, MEMBRANE PROTEIN, ECTODOMAIN, HYDROLASE
1pft:A (GLU15) to (GLU35) N-TERMINAL DOMAIN OF TFIIB, NMR | N-TERMINAL DOMAIN, TFIIB, TRANSCRIPTION INITIATION FACTOR
2co6:B (LEU146) to (SER169) SALMONELLA ENTERICA SAFA PILIN IN COMPLEX WITH THE SAFB CHAPERONE (TYPE I) | PILUS SUBUNIT, ADHESION, STRAND COMPLEMENTATION, PATHOGENESIS, CHAPERONE, FIBRIL PROTEIN
3t25:A (GLN30) to (SER54) TMAO-GROWN ORTHORHOMBIC TRYPSIN (BOVINE) | PROTEASE, HYDROLASE
3t27:A (GLN30) to (SER54) ORTHORHOMBIC TRYPSIN (BOVINE) IN THE PRESENCE OF BETAINE | PROTEASE, HYDROLASE
3gas:A (ASP99) to (SER131) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI HEME OXYGENASE HUGZ IN COMPLEX WITH HEME | HEME OXYGENASE, FMN-BINDING SPLIT BARREL, OXIDOREDUCTASE
3gas:B (ASP99) to (VAL133) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI HEME OXYGENASE HUGZ IN COMPLEX WITH HEME | HEME OXYGENASE, FMN-BINDING SPLIT BARREL, OXIDOREDUCTASE
3gas:C (ASP99) to (SER131) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI HEME OXYGENASE HUGZ IN COMPLEX WITH HEME | HEME OXYGENASE, FMN-BINDING SPLIT BARREL, OXIDOREDUCTASE
3gas:D (ASP99) to (VAL133) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI HEME OXYGENASE HUGZ IN COMPLEX WITH HEME | HEME OXYGENASE, FMN-BINDING SPLIT BARREL, OXIDOREDUCTASE
3gas:E (ASP99) to (VAL133) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI HEME OXYGENASE HUGZ IN COMPLEX WITH HEME | HEME OXYGENASE, FMN-BINDING SPLIT BARREL, OXIDOREDUCTASE
3gas:F (ASP99) to (VAL133) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI HEME OXYGENASE HUGZ IN COMPLEX WITH HEME | HEME OXYGENASE, FMN-BINDING SPLIT BARREL, OXIDOREDUCTASE
1djg:A (LYS655) to (TRP684) PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH LANTHANUM | PHOSPHORIC DIESTER HYDROLASE, HYDROLASE, LIPID DEGRADATION, TRANSDUCER, CALCIUM-BINDING, PHOSPHOLIPASE C, PHOSPHOINOSITIDE-SPECIFIC
1pgu:B (THR501) to (THR524) YEAST ACTIN INTERACTING PROTEIN 1 (AIP1), SE-MET PROTEIN, MONOCLINIC CRYSTAL FORM | WD REPEAT, SEVEN-BLADED BETA-PROPELLER, PROTEIN BINDING
2qmd:B (MET79) to (GLY102) STRUCTURE OF BACE BOUND TO SCH722924 | BACE1, PROTEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
2qmf:B (MET79) to (GLY102) STRUCTURE OF BACE BOUND TO SCH735310 | BACE1, PROTEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
1djx:A (LYS655) to (TRP684) PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-1,4,5-TRISPHOSPHATE | PHOSPHORIC DIESTER HYDROLASE, HYDROLASE, LIPID DEGRADATION, TRANSDUCER, CALCIUM-BINDING, PHOSPHOLIPASE C, PHOSPHOINOSITIDE-SPECIFIC
1dl6:A (LEU23) to (GLY42) SOLUTION STRUCTURE OF HUMAN TFIIB N-TERMINAL DOMAIN | ZINC RIBBON, GENE REGULATION
1dle:A (TRP29) to (ALA55) FACTOR B SERINE PROTEASE DOMAIN | SERINE PROTEASE, COMPLEMENT SYSTEM, FACTOR B, PROTEIN- PROTEIN INTERACTION, ACTIVATION MECHANISM, BETA-BARREL FOLD, , HYDROLASE
1dm4:B (GLN30) to (LEU53) SER195ALA MUTANT OF HUMAN THROMBIN COMPLEXED WITH FIBRINOPEPTIDE A (7- 16) | MUTANT THROMBIN, RESIDUAL CATALYTIC ACTIVITY, FIBRINOPEPTIDE A, HYDROLASE
3gco:A (VAL154) to (ASP193) CRYSTAL STRUCTURE OF DEGS H198P/D320A MUTANT MODIFIED BY DFP IN COMPLEX WITH DNRDGNVYQF OMP PEPTIDE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, ALLOSTERY, HYDROLASE, SERINE PROTEASE, HYDROLASE-HYDROLASE ACTIVATOR COMPLEX
3gdi:A (LYS266) to (ARG314) MAMMALIAN CLOCK PROTEIN MPER2 - CRYSTAL STRUTURE OF A PAS DOMAIN FRAGMENT | TANDEM PAS DOMAINS, BIOLOGICAL RHYTHMS, CYTOPLASM, NUCLEUS, PHOSPHOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION
4xvo:A (VAL133) to (GLY161) L,D-TRANSPEPTIDASE FROM MYCOBACTERIUM SMEGMATIS | L, D-TRANSPEPTIDASE, MYCOBACTERIUM, STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG
4xvo:C (VAL133) to (GLY161) L,D-TRANSPEPTIDASE FROM MYCOBACTERIUM SMEGMATIS | L, D-TRANSPEPTIDASE, MYCOBACTERIUM, STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG
3gds:A (VAL154) to (ASP193) CRYSTAL STRUCTURE OF DEGS H198P/D320A MUTANT MODIFIED BY DFP IN COMPLEX WITH DNRDGNVYYF PEPTIDE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE, HYDROLASE-HYDROLASE ACTIVATOR COMPLEX
3gdv:A (VAL154) to (ASP193) CRYSTAL STRUCTURE OF DEGS H198P/D320A MUTANT MODIFIED BY DFP AND IN COMPLEX WITH YQF PEPTIDE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, PERIPLASM, SERINE PROTEASE, HYDROLASE/HYDROLASE ACTIVATOR COMPLEX
3gdv:B (VAL154) to (ASP193) CRYSTAL STRUCTURE OF DEGS H198P/D320A MUTANT MODIFIED BY DFP AND IN COMPLEX WITH YQF PEPTIDE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, PERIPLASM, SERINE PROTEASE, HYDROLASE/HYDROLASE ACTIVATOR COMPLEX
4isq:B (VAL895) to (VAL919) BINDING DOMAIN OF BOTULINUM NEUROTOXIN DC IN COMPLEX WITH HUMAN SYNAPTOTAGMIN I | MEMBRANE BINDING, SYNAPTOTAGMIN AND GANGLIOSIDE BINDING, TOXIN
4isr:A (VAL895) to (ASN922) BINDING DOMAIN OF BOTULINUM NEUROTOXIN DC IN COMPLEX WITH RAT SYNAPTOTAGMIN II | MEMBRANE BINDING, SYNAPTOTAGMIN AND GANGLIOSIDE BINDING, TOXIN
2cvh:B (LEU190) to (GLU220) CRYSTAL STRUCTURE OF THE RADB RECOMBINASE | RADB, FILAMENT FORMATION, HOMOLOGOUS RECOMBINATION, ATPASE DOMAIN, HYPERTHERMOPHILE, DNA BINDING PROTEIN
2qrk:A (THR293) to (SER317) CRYSTAL STRUCTURE OF AMP-BOUND SACCHAROPINE DEHYDROGENASE (L-LYS FORMING) FROM SACCHAROMYCES CEREVISIAE | AMP, ROSSMANN FOLD, ALPHA-AMINOADIPATE PATHWAY, FUNGAL LYSINE BIOSYNTHESIS, ACETYLATION, AMINO-ACID BIOSYNTHESIS, CYTOPLASM, NAD, OXIDOREDUCTASE
2qrl:A (THR293) to (ASP319) CRYSTAL STRUCTURE OF OXALYLGLYCINE-BOUND SACCHAROPINE DEHYDROGENASE (L-LYS FORMING) FROM SACCHAROMYCES CEREVISIAE | OXALYLGLYCINE, ROSSMANN FOLD, ALPHA-AMINOADIPATE PATHWAY, FUNGAL LYSINE BIOSYNTHESIS, ACETYLATION, AMINO-ACID BIOSYNTHESIS, CYTOPLASM, NAD, OXIDOREDUCTASE
3t5f:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH MI340 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, HIRUDIN, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ggu:B (PRO9) to (GLU35) HIV PR DRUG RESISTANT PATIENT'S VARIANT IN COMPLEX WITH DARUNAVIR | DARUNVIR, RESISTANCE, MUTATION SCORE, HIV PROTEASE, TMC-114, HYDROLASE
4xyc:A (TYR16) to (PHE49) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
4xyc:N (TYR16) to (ASP50) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
4xyc:T (TYR16) to (PHE49) NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | LIGASE, ATP BINDING, LIGASE-LIGASE INHIBITOR COMPLEX
1dst:A (MET30) to (SER54) MUTANT OF FACTOR D WITH ENHANCED CATALYTIC ACTIVITY | COMPLEMENT ACTIVATING ENZYME, HYDROLASE, SERINE PROTEASE, FACTOR D, HYDROLASE (SERINE PROTEASE)
1dsu:A (MET30) to (SER54) HUMAN FACTOR D, COMPLEMENT ACTIVATING ENZYME | COMPLEMENT ACTIVATING ENZYME, HYDROLASE, SERINE PROTEASE, HYDROLASE (SERINE PROTEASE)
3gi3:A (THR7) to (PRO29) CRYSTAL STRUCTURE OF A N-PHENYL-N'-NAPHTHYLUREA ANALOG IN COMPLEX WITH P38 MAP KINASE | TWO LOBE KINASE STRUCTURE, N-LOBE BETA-SHEET, C-LOBE ALPHA- HELIX, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3gi5:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, KB62 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, PROTEASE INHIBITORS, HIV-1 PROTEASE, ASPARTYL PROTEASE, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1due:A (LEU156) to (GLY188) CRYSTAL STRUCTURE OF EXFOLIATIVE TOXIN A S195A MUTANT | SUPERANTIGENS, PROTEASE, EPIDERMIS, TOXIN, HYDROLASE
3gj9:A (PHE31) to (GLN79) CRYSTAL STRUCTURE OF TIP-1 IN COMPLEX WITH C-TERMINAL OF KIR2.3 | TIP-1, KIR2.3, PDZ DOMAIN, CYTOPLASM, NUCLEUS, PHOSPHOPROTEIN, WNT SIGNALING PATHWAY, SIGNALING PROTEIN
1dva:H (GLN30) to (SER54) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE PEPTIDE EXOSITE INHIBITOR E-76 AND COAGULATION FACTOR VIIA | PROTEIN-PEPTIDE COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1dva:I (GLN30) to (SER54) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE PEPTIDE EXOSITE INHIBITOR E-76 AND COAGULATION FACTOR VIIA | PROTEIN-PEPTIDE COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ixp:A (GLU12) to (ASP43) CRYSTAL STRUCTURE OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE (MELK) | PROTEIN KINASE, REGULATED BY PHOSPHORYLATION, TRANSFERASE
2qtw:B (LEU455) to (SER485) THE CRYSTAL STRUCTURE OF PCSK9 AT 1.9 ANGSTROMS RESOLUTION REVEALS STRUCTURAL HOMOLOGY TO RESISTIN WITHIN THE C-TERMINAL DOMAIN | PRO-PROTEIN CONVERTASE, CORONARY HEART DISEASE, HYPERCHOLESTEROLEMIA, LOW DENSITY LIPOPROTEIN RECEPTOR, AUTOCATALYTIC CLEAVAGE, CHOLESTEROL METABOLISM, DISEASE MUTATION, GLYCOPROTEIN, HYDROLASE, LIPID METABOLISM, PHOSPHORYLATION, PROTEASE, SECRETED, SERINE PROTEASE, STEROID METABOLISM, ZYMOGEN
4iyg:B (GLU306) to (TYR333) STRUCTURE OF STRICTOSIDINE SYNTHASE IN COMPLEX WITH 2-(1H-INDOL-3-YL)- N-METHYLETHANAMINE | STRICTOSIDINE SYNTHASE, LYASE-LYASE INHIBITOR COMPLEX
1dy7:B (VAL470) to (VAL505) CYTOCHROME CD1 NITRITE REDUCTASE, CO COMPLEX | ENZYME, NITRITE REDUCTASE, OXIDOREDUCTASE
1e0k:A (ASP497) to (ASN536) GP4D HELICASE FROM PHAGE T7 | HELICASE, ATPASE, DNA REPLICATION
1e0k:D (ASP497) to (ASN536) GP4D HELICASE FROM PHAGE T7 | HELICASE, ATPASE, DNA REPLICATION
1e0m:A (GLY7) to (THR29) PROTOTYPE WW DOMAIN | SH3 PROTOTYPE, WWPROTOTYPE, PROTEIN DESIGN, DE NOVO PROTEIN
1e0n:A (PRO7) to (LEU29) YJQ8WW DOMAIN FROM SACCHAROMYCES CEREVISAE | YJQ8WW DOMAIN, WW DOMAIN, SACCHAROMYCES CEREVISAE, YJQ8 PROTEIN
1ptq:A (HIS231) to (HIS269) PROTEIN KINASE C DELTA CYS2 DOMAIN | PHOSPHOTRANSFERASE
1ptr:A (HIS231) to (HIS269) PROTEIN KINASE C DELTA CYS2 DOMAIN COMPLEXED WITH PHORBOL- 13-ACETATE | PHOSPHOTRANSFERASE
1e0z:A (GLY78) to (VAL114) [2FE-2S]-FERREDOXIN FROM HALOBACTERIUM SALINARUM | ELECTRON TRANSPORT, IRON-SULFUR PROTEIN, NMR, FERREDOXIN, HALOPHILIC
4y2o:A (SER129) to (LYS158) STRUCTURE OF CFA/I PILI CHAPERONE-MAJOR SUBUNIT COMPLEX (CFAA-CFAB) | ENTEROTOXIGENIC ESCHERICHIA COLI, PERIPLASMIC CHAPERONE, MAJOR PILIN, SELF-ASSEMBLY, FIMBRIAE, STRUCTURAL PROTEIN
1e1e:A (THR470) to (GLU490) CRYSTAL STRUCTURE OF A MONOCOT (MAIZE ZMGLU1) BETA-GLUCOSIDASE | GLYCOSIDE HYDROLASE, BETA-GLUCOSIDASE, FAMILY 1, RETENTION OF THE ANOMERIC CONFIGURATION, HYDROLASE
2qxj:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN KALLIKREIN 7 IN COMPLEX WITH SUC- ALA-ALA-PRO-PHE-CHLOROMETHYLKETONE AND COPPER | COPPER, HISTIDINE LIGANDS, CATALYTIC TRIAD HIS, ALTERNATIVE SPLICING, GLYCOPROTEIN, HYDROLASE, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN
2qxi:A (GLN30) to (THR54) HIGH RESOLUTION STRUCTURE OF HUMAN KALLIKREIN 7 IN COMPLEX WITH SUC-ALA-ALA-PRO-PHE-CHLOROMETHYLKETONE | S1 POCKET, CHLOROMETHYL KETONE, ALTERNATE CONFORMATIONS, ALTERNATIVE SPLICING, GLYCOPROTEIN, HYDROLASE, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN
3gnq:C (GLY58) to (ALA78) CRYSTAL STRUCTURE OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, TYPE I FROM BURKHOLDERIA PSEUDOMALLEI | DECODE BIOSTRUCTURES, SSGCID, UWPPG, SBRI, NIAID, OXIDOREDUCTASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
1e1r:D (ASN34) to (ASP64) BOVINE MITOCHONDRIAL F1-ATPASE INHIBITED BY MG2+ADP AND ALUMINIUM FLUORIDE | ATP PHOSPHORYLASE, ATP PHOSPHORYLASE (H+ TRANSPORTING), ATP SYNTHASE, F1FO ATP SYNTHASE, F1-ATPASE
1pvu:B (GLY47) to (ASN73) THE CRYSTAL STRUCTURE OF PVUII ENDONUCLEASE REVEALS EXTENSIVE STRUCTURAL HOMOLOGIES TO ECORV | TYPE II RESTRICTION ENDONUCLEASE
2qyi:A (GLN30) to (SER54) CRYSTAL STRUCTURE OF A BINARY COMPLEX BETWEEN AN ENGINEERED TRYPSIN INHIBITOR AND BOVINE TRYPSIN | P1 MUTANT, TRYPSIN INHIBITOR, BOVINE TRYPSIN, COMPLEX, CALCIUM, DIGESTION, HYDROLASE, METAL-BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, PROTEASE INHIBITOR, SERINE PROTEASE INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
2qyi:D (VAL919) to (ASP948) CRYSTAL STRUCTURE OF A BINARY COMPLEX BETWEEN AN ENGINEERED TRYPSIN INHIBITOR AND BOVINE TRYPSIN | P1 MUTANT, TRYPSIN INHIBITOR, BOVINE TRYPSIN, COMPLEX, CALCIUM, DIGESTION, HYDROLASE, METAL-BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, PROTEASE INHIBITOR, SERINE PROTEASE INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1pwa:A (GLU123) to (LEU169) CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 19 | BETA TREFOIL, DISULPHIDE BONDS, HORMONE-GROWTH FACTOR COMPLEX
1e2r:B (VAL470) to (VAL505) CYTOCHROME CD1 NITRITE REDUCTASE, REDUCED AND CYANIDE BOUND | OXIDOREDUCTASE, DENITRIFICATION, ELECTRON TRANSPORT, PERIPLASMIC, CYANIDE
1e2w:A (ASN99) to (PRO129) N168F MUTANT OF CYTOCHROME F FROM CHLAMYDOMONAS REINHARDTII | ELECTRON TRANSPORT PROTEINS, INTERNAL WATER CHAIN, PHOTOSYNTHETIC FUNCTION IMPAIRED
1e2z:C (ASN99) to (PRO129) Q158L MUTANT OF CYTOCHROME F FROM CHLAMYDOMONAS REINHARDTII | ELECTRON TRANSPORT PROTEINS, INTERNAL WATER CHAIN, PHOTOSYNTHETIC FUNCTION IMPAIRED
1e30:A (THR23) to (ALA44) CRYSTAL STRUCTURE OF THE MET148GLN MUTANT OF RUSTICYANIN AT 1.5 ANGSTROM RESOLUTION | RUSTICYANIN, MUTANT, AXIAL LIGAND, CUPREDOXIN
2d5f:A (PRO160) to (SER203) CRYSTAL STRUCTURE OF RECOMBINANT SOYBEAN PROGLYCININ A3B4 SUBUNIT, ITS COMPARISON WITH MATURE GLYCININ A3B4 SUBUNIT, RESPONSIBLE FOR HEXAMER ASSEMBLY | GLYCININ, SOYBEAN, GLOBULIN, 11S,SEED STORAGE PROTEIN, PLANT PROTEIN
2d74:A (ILE381) to (ILE409) CRYSTAL STRUCTURE OF TRANSLATION INITIATION FACTOR AIF2BETAGAMMA HETERODIMER | PROTEIN COMPLEX, TRANSLATION
2d74:B (LYS116) to (PRO136) CRYSTAL STRUCTURE OF TRANSLATION INITIATION FACTOR AIF2BETAGAMMA HETERODIMER | PROTEIN COMPLEX, TRANSLATION
4y52:A (THR170) to (THR204) CRYSTAL STRUCTURE OF 5-CARBOXYCYTOSINE RECOGNITION BY RNA POLYMERASE II DURING TRANSCRIPTION ELONGATION. | RNA POLYMERASE II, 5-CARBOXYCYTOSINE, TRANSCRIPTION ELONGATION, DNA DEMETHYLATION, TRANSCRIPTION-DNA-RNA COMPLEX
2r2m:B (GLN51) to (THR76) 2-(2-CHLORO-6-FLUOROPHENYL)ACETAMIDES AS POTENT THROMBIN INHIBITORS | THROMBIN, ACUTE PHASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, KRINGLE, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, PROTEASE INHIBITOR, SERINE PROTEASE INHIBITOR, SULFATION, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3tcj:A (THR5) to (PRO42) CCDB DIMER FROM V. FISHERI IN COMPLEX WITH ONE C-TERMINAL DOMAIN OF F- PLASMID CCDA | ALPHA+BETA SH3 DOMAIN INTRINSICALLY DISORDERED, TOXIN-ANTITOXIN COMPLEX
3tdb:A (PRO9) to (TRP34) HUMAN PIN1 BOUND TO TRANS PEPTIDOMIMETIC INHIBITOR | PPIASE DOMAIN, WW DOMAIN, PEPTIDYL-PROLYL ISOMERASE, ISOMERASE- INHIBITOR COMPLEX
3gs9:A (ASP285) to (ASN321) CRYSTAL STRUCTURE OF PROPHAGE TAIL PROTEIN GP18 (NP_465809.1) FROM LISTERIA MONOCYTOGENES EGD-E AT 1.70 A RESOLUTION | NP_465809.1, PROPHAGE TAIL PROTEIN GP18, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, STRUCTURAL PROTEIN
3teh:B (GLY621) to (ALA654) CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS PHENYLALANYL-TRNA SYNTHETASE COMLEXED WITH L-DOPA | AARS, L-DOPA, TRNA, LIGASE
2r6a:B (ILE412) to (ASN440) CRYSTAL FORM BH1 | HELICASE, PRIMASE, REPLICATION, DNAB, DNAG
3gtj:K (LYS18) to (HIS40) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 13MER RNA | TRANSCRIPTION, TRANSFERASE/DNA-RNA HYBRID, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR
2dfs:A (ALA11) to (GLU43) 3-D STRUCTURE OF MYOSIN-V INHIBITED STATE | MYOSIN-V, INHIBITED STATE, CALMODULIN, CRYOELECTRON TOMOGRAPHY, CONTRACTILE PROTEIN-TRANSPORT PROTEIN COMPLEX
2dfs:M (ALA11) to (GLU43) 3-D STRUCTURE OF MYOSIN-V INHIBITED STATE | MYOSIN-V, INHIBITED STATE, CALMODULIN, CRYOELECTRON TOMOGRAPHY, CONTRACTILE PROTEIN-TRANSPORT PROTEIN COMPLEX
4y7n:A (THR173) to (THR204) THE STRUCTURE INSIGHT INTO 5-CARBOXYCYTOSINE RECOGNITION BY RNA POLYMERASE II DURING TRANSCRIPTION ELONGATION. | RNA POLYMERASE II, 5-CARBOXYCYTOSINE, TRANSCRIPTION ELONGATION, DNA DEMETHYLATION, TRANSCRIPTION-DNA-RNA COMPLEX
4j83:A (LEU169) to (PHE193) SET7/9 IN COMPLEX WITH TAF10K189A PEPTIDE AND ADOMET | SET DOMAIN, LYSINE METHYLTRANSFERASE, TRANSFERASE-PEPTIDE COMPLEX
3gtk:K (LYS18) to (HIS40) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 18MER RNA | TRANSCRIPTION, TRANSFERASE/DNA-RNA HYBRID, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR
1q31:A (HIS20) to (ASN44) CRYSTAL STRUCTURE OF THE TOBACCO ETCH VIRUS PROTEASE C151A MUTANT | 3C-TYPE PROTEASE, TEV, TWO-DOMAIN, ANTIPARALLEL, BETA-BARREL, TRYPSIN-LIKE, C151A, VIRAL PROTEIN, HYDROLASE
1q31:A (GLU107) to (TRP143) CRYSTAL STRUCTURE OF THE TOBACCO ETCH VIRUS PROTEASE C151A MUTANT | 3C-TYPE PROTEASE, TEV, TWO-DOMAIN, ANTIPARALLEL, BETA-BARREL, TRYPSIN-LIKE, C151A, VIRAL PROTEIN, HYDROLASE
1q31:B (HIS20) to (ASN44) CRYSTAL STRUCTURE OF THE TOBACCO ETCH VIRUS PROTEASE C151A MUTANT | 3C-TYPE PROTEASE, TEV, TWO-DOMAIN, ANTIPARALLEL, BETA-BARREL, TRYPSIN-LIKE, C151A, VIRAL PROTEIN, HYDROLASE
1q31:B (GLU107) to (TRP143) CRYSTAL STRUCTURE OF THE TOBACCO ETCH VIRUS PROTEASE C151A MUTANT | 3C-TYPE PROTEASE, TEV, TWO-DOMAIN, ANTIPARALLEL, BETA-BARREL, TRYPSIN-LIKE, C151A, VIRAL PROTEIN, HYDROLASE
3th3:H (GLN30) to (SER54) MG2+ IS REQUIRED FOR OPTIMAL FOLDING OF THE GAMMA-CARBOXYGLUTAMIC ACID (GLA) DOMAINS OF VITAMIN K-DEPENDENT CLOTTING FACTORS AT PHYSIOLOGICAL CA2+ | HYDROLASE, BLOOD CLOTTING, SERINE PROTEASE, BLOOD COAGULATION, SOLUBLE TISSUE FACTOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4j9a:E (PHE84) to (PHE118) ENGINEERED DIGOXIGENIN BINDER DIG10.3 | ENGINEERED, COMPUTATIONALLY DESIGNED, DIGOXIGENIN-BINDING, DIGOXIGENIN BINDING PROTEIN
3gtm:K (LYS18) to (HIS40) CO-COMPLEX OF BACKTRACKED RNA POLYMERASE II WITH TFIIS | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA- DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, TRANSCRIPTION REGULATION, TRANSFERASE/DNA-RNA HYBRID COMPLEX
1q3x:A (GLN459) to (THR480) CRYSTAL STRUCTURE OF THE CATALYTIC REGION OF HUMAN MASP-2 | COMPLEMENT, SERINE PROTEASE, MODULAR STRUCTURE, HINGE BENDING, AUTOACTIVATION, HYDROLASE
1q3x:B (GLN459) to (THR480) CRYSTAL STRUCTURE OF THE CATALYTIC REGION OF HUMAN MASP-2 | COMPLEMENT, SERINE PROTEASE, MODULAR STRUCTURE, HINGE BENDING, AUTOACTIVATION, HYDROLASE
3gto:K (LYS18) to (HIS40) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 15MER RNA | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, ZINC- FINGER, DNA DAMAGE, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
3gtp:I (MET13) to (GLU37) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 24MER RNA | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA- DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, TRANSFERASE/DNA-RNA HYBRID COMPLEX
4jbq:A (ASP132) to (PHE165) NOVEL AURORA KINASE INHIBITORS REVEAL MECHANISMS OF HURP IN NUCLEATION OF CENTROSOMAL AND KINETOCHORE MICROTUBULES | AURORA KINASE INHIBITORS, HURP, MITOTIC SPINDLE, TRANSFERASE
1ec3:A (ARG8) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR MSA367 | DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3gtq:I (ASN12) to (GLU37) BACKTRACKED RNA POLYMERASE II COMPLEX INDUCED BY DAMAGE | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, ZINC- FINGER, DNA DAMAGE, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
3gtq:K (LYS18) to (HIS40) BACKTRACKED RNA POLYMERASE II COMPLEX INDUCED BY DAMAGE | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, ZINC- FINGER, DNA DAMAGE, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
3tjn:D (VAL183) to (THR217) HTRA1 CATALYTIC DOMAIN, APO FORM | PROTEASE, HYDROLASE
3tjo:B (VAL184) to (THR217) HTRA1 CATALYTIC DOMAIN, MUTATIONALLY INACTIVATED | PEPTIDASE, HYDROLASE
3tjo:D (ARG227) to (ASP257) HTRA1 CATALYTIC DOMAIN, MUTATIONALLY INACTIVATED | PEPTIDASE, HYDROLASE
4jcn:A (SER89) to (THR114) STRUCTURE OF ESP, SERINE PROTEASE FROM STAPHYLOCOCCUS EPIDERMIDIS | EXTRACELLULAR SERINE PROTEASE, ESP, BIOFILM, GLUTAMYL ENDOPEPTIDASE, PROTEASE, HYDROLASE
3tk6:A (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH D46-5241 | GLYCOPROTEIN, HYDROLASE, SERINE PROTEASE, PLASMA, BLOOD, COAGULATION FACTOR, CALCIUM-BINDING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3tkk:C (GLY105) to (ILE132) CRYSTAL STRUCTURE ANALYSIS OF A RECOMBINANT PREDICTED ACETAMIDASE/ FORMAMIDASE FROM THE THERMOPHILE THERMOANAEROBACTER TENGCONGENSIS | BETA/ALPHA STRUCTURE, HYDROLASE
2dqy:A (PRO1023) to (GLY1052) CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH CHOLATE AND PALMITATE | CHOLESTEROL METABOLISM, FOAM CELLS, MACROPHAGE, MONOCYTE, ATHEROSCLEROSIS, HYDROLASE
2dqy:B (PRO2023) to (GLY2052) CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH CHOLATE AND PALMITATE | CHOLESTEROL METABOLISM, FOAM CELLS, MACROPHAGE, MONOCYTE, ATHEROSCLEROSIS, HYDROLASE
2dqy:C (PRO3023) to (GLY3052) CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH CHOLATE AND PALMITATE | CHOLESTEROL METABOLISM, FOAM CELLS, MACROPHAGE, MONOCYTE, ATHEROSCLEROSIS, HYDROLASE
2dqz:A (PRO1023) to (GLY1052) CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH HOMATROPINE, COENZYME A, AND PALMITATE | CHOLESTEROL, ESTERASE, HYDROLASE
2dqz:B (PRO2023) to (GLY2052) CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH HOMATROPINE, COENZYME A, AND PALMITATE | CHOLESTEROL, ESTERASE, HYDROLASE
3tl9:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV PROTEASE MODEL PRECURSOR/SAQUINAVIR COMPLEX | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1q90:A (ASN99) to (PRO129) STRUCTURE OF THE CYTOCHROME B6F (PLASTOHYDROQUINONE : PLASTOCYANIN OXIDOREDUCTASE) FROM CHLAMYDOMONAS REINHARDTII | MEMBRANE PROTEIN COMPLEX, PHOTOSYNTHESIS, ELECTRON TRANSFER, OXYDOREDUCTASE, CHLOROPHYLL, BETA-CAROTENE, STIGMATELLIN, SULFOQUINOVOSYLDIACYLGLYCEROL, MONOGALACTOSYLDIACYLGLYCEROL
3tmh:E (GLY389) to (GLU425) CRYSTAL STRUCTURE OF DUAL-SPECIFIC A-KINASE ANCHORING PROTEIN 2 IN COMPLEX WITH CAMP-DEPENDENT PROTEIN KINASE A TYPE II ALPHA AND PDZK1 | ALPHA HELICAL BUNDLE, PDZ FOLD, ANCHORING PROTEIN, PKA, PDZ PROTEINS, MEMBRANE, TRANSPORT PROTEIN-SIGNALING PROTEIN COMPLEX
2ra9:A (LEU61) to (GLU82) CRYSTAL STRUCTURE OF A DUF1285 FAMILY PROTEIN (SBAL_2486) FROM SHEWANELLA BALTICA OS155 AT 1.40 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
2dsv:A (THR286) to (GLN310) INTERACTIONS OF PROTECTIVE SIGNALLING FACTOR WITH CHITIN-LIKE POLYSACCHARIDE: CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN SIGNALLING PROTEIN FROM SHEEP (SPS-40) AND A HEXASACCHARIDE AT 2.5A RESOLUTION | SPS-40, HEXASACCHARIDE, COMPLEX, INVOLUTION, SIGNALING PROTEIN
2dsw:A (THR286) to (GLN310) BINDING OF CHITIN-LIKE POLYSACCHARIDES TO PROTECTIVE SIGNALLING FACTOR: CRYSTAL STRUCTURE OF THE COMPLEX OF SIGNALLING PROTEIN FROM SHEEP (SPS-40) WITH A PENTASACCHARIDE AT 2.8 A RESOLUTION | SPS-40, PENTASACCHARIDE, COMPLEX, SIGNALING PROTEIN
2dt2:A (THR286) to (GLN310) CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN GOAT SIGNALLING PROTEIN WITH PENTASACCHARIDE AT 2.9A RESOLUTION | SPG-40, PENTASACCHARIDE, COMPLEX, SIGNALING PROTEIN
3gy3:A (GLN30) to (SER54) A COMPARATIVE STUDY ON THE INHIBITION OF BOVINE BETA-TRYPSIN BY BIS- BENZAMIDINES DIMINAZENE AND PENTAMIDINE BY X-RAY CRYSTALLOGRAPHY AND ITC | BOVINE BETA-TRYPSIN, PENTAMIDINE, PROTEIN-LIGAND COMPLEX, PROTEIN- LIGAND INTERACTION, CALCIUM, DIGESTION, DISULFIDE BOND, HYDROLASE, METAL-BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN
1qb6:A (GLN21) to (SER43) BOVINE TRYPSIN 3,3'-[3,5-DIFLUORO-4-METHYL-2, 6- PYRIDINEDIYLBIS(OXY)]BIS(BENZENECARBOXIMIDAMIDE) (ZK- 805623) COMPLEX | HYDROLASE, SERINE PROTEINASE, PROTEIN-INHIBITOR COMPLEX, S1 POCKET, FACTOR XA
1qbn:A (GLN21) to (SER43) BOVINE TRYPSIN 2-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-6- [3-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)PHENOXY]PYRIDINE-4- CARBOXYLIC ACID (ZK-806688) COMPLEX | HYDROLASE, SERINE PROTEINASE, PROTEIN-INHIBITOR COMPLEX, S1 POCKET
4yc8:A (ASP241) to (LEU273) C-HELIX-OUT BINDING OF DASATINIB ANALOG TO C-ABL KINASE | KINASE, C-HELIX-OUT, TRANSFERASE
1qcp:A (GLN30) to (SER54) CRYSTAL STRUCTURE OF THE RWJ-51084 BOVINE PANCREATIC BETA- TRYPSIN AT 1.8 A | SERINE PROTEASE-INHIBITOR COMPLEX, HYDROLASE
3gyx:I (ARG190) to (ALA224) CRYSTAL STRUCTURE OF ADENYLYLSULFATE REDUCTASE FROM DESULFOVIBRIO GIGAS | ADENYLYLSULFATE REDUCTASE, OXIDOREDUCTASE
2duv:A (ASN3) to (LYS34) STRUCTURE OF CDK2 WITH A 3-HYDROXYCHROMONES | PROTEIN KINASE, SERINE/THREONINE-PROTEIN KINASE, CELL DIVISION, TRANSFERASE
3gzb:A (ASN98) to (LEU140) CRYSTAL STRUCTURE OF PUTATIVE SNOAL-LIKE POLYKETIDE CYCLASE (YP_001182657.1) FROM SHEWANELLA PUTREFACIENS CN-32 AT 1.44 A RESOLUTION | YP_001182657.1, PUTATIVE SNOAL-LIKE POLYKETIDE CYCLASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
3gzb:C (ASN98) to (ILE141) CRYSTAL STRUCTURE OF PUTATIVE SNOAL-LIKE POLYKETIDE CYCLASE (YP_001182657.1) FROM SHEWANELLA PUTREFACIENS CN-32 AT 1.44 A RESOLUTION | YP_001182657.1, PUTATIVE SNOAL-LIKE POLYKETIDE CYCLASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
3gzb:G (ASN98) to (LEU140) CRYSTAL STRUCTURE OF PUTATIVE SNOAL-LIKE POLYKETIDE CYCLASE (YP_001182657.1) FROM SHEWANELLA PUTREFACIENS CN-32 AT 1.44 A RESOLUTION | YP_001182657.1, PUTATIVE SNOAL-LIKE POLYKETIDE CYCLASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
1eja:A (GLN30) to (SER54) STRUCTURE OF PORCINE TRYPSIN COMPLEXED WITH BDELLASTASIN, AN ANTISTASIN-TYPE INHIBITOR | COMPLEX (HYDROLASE/INHIBITOR), HYDROLASE, INHIBITOR, BDELLASTASIN, ANTISTASIN, TRYPSIN
1qe3:A (HIS3) to (GLY26) PNB ESTERASE | ALPHA-BETA HYDROLASE DIRECTED EVOLUTION
1ekb:B (VAL31) to (SER54) THE SERINE PROTEASE DOMAIN OF ENTEROPEPTIDASE BOUND TO INHIBITOR VAL- ASP-ASP-ASP-ASP-LYS-CHLOROMETHANE | ENTEROPEPTIDASE, TRYPSINOGEN ACTIVATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3h09:A (ILE86) to (GLY111) THE STRUCTURE OF HAEMOPHILUS INFLUENZAE IGA1 PROTEASE | SERINE PROTEASE, IMMUNOGLOBULIN A1, BETA HELIX, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, TRANSMEMBRANE, VIRULENCE, ZYMOGEN
3h09:B (ILE86) to (GLY111) THE STRUCTURE OF HAEMOPHILUS INFLUENZAE IGA1 PROTEASE | SERINE PROTEASE, IMMUNOGLOBULIN A1, BETA HELIX, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, TRANSMEMBRANE, VIRULENCE, ZYMOGEN
3h09:B (GLY409) to (GLY429) THE STRUCTURE OF HAEMOPHILUS INFLUENZAE IGA1 PROTEASE | SERINE PROTEASE, IMMUNOGLOBULIN A1, BETA HELIX, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, TRANSMEMBRANE, VIRULENCE, ZYMOGEN
4ye9:A (ASP739) to (ARG764) THE CRYSTAL STRUCTURE OF THE G45V MUTANT OF HUMAN GLNRS | AMINOACYL-TRNA SYNTHETASE, CLASS I AARS, GLUTAMINE, LIGASE
1elv:A (ASN352) to (MET378) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN COMPLEMENT C1S PROTEASE | TRYPSIN-LIKE SERIN PROTEASE, CCP (OR SUSHI OR SCR)MODULE, HYDROLASE
4yes:B (GLN378) to (THR403) THROMBIN IN COMPLEX WITH (S)-(4-CHLORO-2-((1-(5-METHYL-1H-PYRROLE-2- CARBONYL)PYRROLIDINE-2-CARBOXAMIDO)METHYL)PHENYL)METHANAMINIUM | SULFO-HIRUDIN, INHIBITOR, COMPLEX, THROMBIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2rg3:A (MET30) to (SER54) COVALENT COMPLEX STRUCTURE OF ELASTASE | ELASTASE, COMPLEX, COVALENT, DISEASE MUTATION, GLYCOPROTEIN, HYDROLASE, PROTEASE, SERINE PROTEASE, ZYMOGEN
2rgk:A (SER27) to (LEU50) FUNCTIONAL ANNOTATION OF ESCHERICHIA COLI YIHS-ENCODED PROTEIN | N-ACYL-D-GLUCOSAMINE 2-EPIMERASE PROTEIN FAMILY, ISOMERASE
3ttp:B (LYS45) to (GLY78) STRUCTURE OF MULTIRESISTANT HIV-1 PROTEASE IN COMPLEX WITH DARUNAVIR | HYDROLASE, VIRAL PRATICLE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2e03:A (HIS369) to (THR407) CRYSTAL STRUCTURE OF NQ67E MUTANT OF YEAST BLEOMYCIN HYDROLASE | BLEOMYCIN HYDROLASE, THIOL PROTEASE, C1 PROTEAS, HYDROLASE
1ep5:B (GLY198) to (PRO217) CRYSTAL STRUCTURE OF THE CONSERVED CORE DOMAIN OF VENEZUALAN EQUINE ENCEPHALITIS CAPSID PROTEIN | BETA BARREL, HYDROLASE
1ep5:C (GLY198) to (PRO217) CRYSTAL STRUCTURE OF THE CONSERVED CORE DOMAIN OF VENEZUALAN EQUINE ENCEPHALITIS CAPSID PROTEIN | BETA BARREL, HYDROLASE
1ep6:A (GLY198) to (PRO217) CRYSTAL STRUCTURE OF THE CONSERVED CORE DOMAIN OF VENEZUALAN EQUINE ENCEPHALITIS CAPSID PROTEIN | BETA BARREL, HYDROLASE
1qhr:B (GLN30) to (THR54) NOVEL COVALENT ACTIVE SITE THROMBIN INHIBITORS | PROTEINASE, BLOOD COAGULATION, TRYPSIN LIKE PROTEINASE, COMPLEX (SERINE PROTEASE-INHIBITOR), BLOOD CLOTTING-HYDROLASE INHIBITOR COMPLEX
1eq9:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF FIRE ANT CHYMOTRYPSIN COMPLEXED TO PMSF | CHYMOTRYPSIN, FIRE ANT, SERINE PROTEINASE, HYDROLASE
1eq9:B (GLN330) to (THR354) CRYSTAL STRUCTURE OF FIRE ANT CHYMOTRYPSIN COMPLEXED TO PMSF | CHYMOTRYPSIN, FIRE ANT, SERINE PROTEINASE, HYDROLASE
2ri9:A (LEU1302) to (HIS1329) PENICILLIUM CITRINUM ALPHA-1,2-MANNOSIDASE IN COMPLEX WITH A SUBSTRATE ANALOG | ALTERNATIVE CONFORMATIONS, MODULATION OF ACTIVITY, GLYCOPROTEIN, GLYCOSIDASE, HYDROLASE, SECRETED
1qj6:B (GLN30) to (THR54) NOVEL COVALENT ACTIVE SITE THROMBIN INHIBITORS | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, BLOOD COAGULATION-INHIBITOR COMPLEX, PROTEINASE, BLOOD COAGULATION, TRYPSIN LIKE PROTEINASE, PROTEASE-INHIBITOR COMPLEX, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3h0z:B (ASP132) to (LEU164) AURORA A IN COMPLEX WITH A BISANILINOPYRIMIDINE | PROTEIN:INHIBITOR COMPLEX AURORA-A, CELL CYCLE, SERINE/THREONINE, PROTEIN KINASE, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
2rjg:A (GLY216) to (SER240) CRYSTAL STRUCTURE OF BIOSYNTHETIC ALAINE RACEMASE FROM ESCHERICHIA COLI | ALPHA/BETA BARREL, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, ISOMERASE, PEPTIDOGLYCAN SYNTHESIS, PYRIDOXAL PHOSPHATE
2rjh:B (GLY216) to (SER240) CRYSTAL STRUCTURE OF BIOSYNTHETIC ALAINE RACEMASE IN D- CYCLOSERINE-BOUND FORM FROM ESCHERICHIA COLI | ALPHA/BETA BARREL, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, ISOMERASE, PEPTIDOGLYCAN SYNTHESIS, PYRIDOXAL PHOSPHATE
1esp:A (LYS6) to (LEU31) NEUTRAL PROTEASE MUTANT E144S | INACTIVE MUTANT E144S, HYDROLASE (METALLOPROTEINASE)
1eth:A (SER417) to (ASN446) TRIACYLGLYCEROL LIPASE/COLIPASE COMPLEX | COMPLEX (HYDROLASE-COFACTOR), LIPID DEGRADATION, COMPLEX (HYDROLASE- COFACTOR) COMPLEX
1eth:C (SER417) to (ASN446) TRIACYLGLYCEROL LIPASE/COLIPASE COMPLEX | COMPLEX (HYDROLASE-COFACTOR), LIPID DEGRADATION, COMPLEX (HYDROLASE- COFACTOR) COMPLEX
1etr:H (GLN30) to (THR54) REFINED 2.3 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEXES FORMED WITH THE BENZAMIDINE AND ARGININE-BASED THROMBIN INHIBITORS NAPAP, 4-TAPAP AND MQPA: A STARTING POINT FOR IMPROVING ANTITHROMBOTICS | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3tty:F (GLY511) to (ILE545) CRYSTAL STRUCTURE OF BETA-GALACTOSIDASE FROM BACILLUS CIRCULANS SP. ALKALOPHILUS IN COMPLEX WITH GALACTOSE | TIM BARREL, GLYCOSIDE HYDROLASE, HYDROLASE
3tua:A (GLY170) to (GLN211) CRYSTAL STRUCTURE OF THE BURKHOLDERIA LETHAL FACTOR 1 (BLF1) C94S MUTANT | TOXIN, UNKNOWN FUNCTION
1ql8:A (GLN30) to (SER54) FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN | SERINE PROTEASE, HYDROLASE, SERINE PROTEINASE
1ql9:A (GLN30) to (SER54) FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH RAT TRYPSIN MUTANT X99RT | SERINE PROTEASE, HYDROLASE, SERINE PROTEINASE
3tv7:A (GLY193) to (ASP232) HUMAN RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH RKI1342 | KINASE, DIMER, DIMERIZATION, MYOSIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jmn:A (LEU125) to (GLY153) CRYSTAL STRUCTURE OF LD TRANSPEPTIDASE LDTMT1 FROM M. TUBERCULOSIS | IG-LIKE DOMAIN AND BETA BARREL, CELL WALL MODELLING, TRANSFERASE
4jmr:A (GLY33) to (GLN75) A UNIQUE SPUMAVIRUS GAG N-TERMINAL DOMAIN WITH FUNCTIONAL PROPERTIES OF ORTHORETROVIRAL MATRIX AND CAPSID | GAG, ENV, COILED-COIL, VIRAL PROTEIN, VIRAL PROTEIN-PEPTIDE COMPLEX
4jmr:D (GLU34) to (ARG76) A UNIQUE SPUMAVIRUS GAG N-TERMINAL DOMAIN WITH FUNCTIONAL PROPERTIES OF ORTHORETROVIRAL MATRIX AND CAPSID | GAG, ENV, COILED-COIL, VIRAL PROTEIN, VIRAL PROTEIN-PEPTIDE COMPLEX
2rpr:A (GLU12) to (LYS32) SOLUTION STRUCTURE OF THE FIFTH FLYWCH DOMAIN OF FLYWCH-TYPE ZINC FINGER-CONTAINING PROTEIN 1 | FLYWCH DOMAIN, ALTERNATIVE SPLICING, DNA-BINDING, METAL- BINDING, NUCLEUS, ZINC, ZINC-FINGER, METAL BINDING PROTEIN
3tvj:B (GLN459) to (THR480) CATALYTIC FRAGMENT OF MASP-2 IN COMPLEX WITH ITS SPECIFIC INHIBITOR DEVELOPED BY DIRECTED EVOLUTION ON SGCI SCAFFOLD | IN VITRO EVOLUTION, SPECIFIC INHIBITOR, ALLOSTERY, HYDROLASE
2rqx:A (ASP43) to (ARG66) SOLUTION NMR STRUCTURE OF PMRD FROM KLEBSIELLA PNEUMONIAE | SIGNALING PROTEIN
2rsv:A (GLU27) to (MET56) SOLUTION STRUCTURE OF HUMAN FULL-LENGTH VACCINIA RELATED KINASE 1 (VRK1) | VRK, KINASE, TRANSFERASE
3h3v:L (LYS18) to (HIS40) YEAST RNAP II CONTAINING POLY(A)-SIGNAL SEQUENCE IN THE ACTIVE SITE | TRANSFERASE/DNA/RNA, DNA-BINDING, PHOSPHORYLATION, RNA POLYMERASE II, METAL-BINDING, NUCLEAR PROTEIN, TRANSCRIPTION BUBBLE, ELONGATION COMPLEX, TRANSFERASE, TRANSCRIPTION, POLYADENYLATION, TERMINATION, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, ZINC-FINGER, DNA DAMAGE, DNA REPAIR, MRNA PROCESSING, TRANSFERASE-DNA-RNA COMPLEX
2e32:C (GLY149) to (ASP187) STRUCTURAL BASIS FOR SELECTION OF GLYCOSYLATED SUBSTRATE BY SCFFBS1 UBIQUITIN LIGASE | UBIQUITIN, SCF, UBIQUITIN LIGASE, FBS1
4jqr:A (GLY84) to (ILE130) CRYSTAL STRUCTURE OF A DUF4465 FAMILY PROTEIN (BACCAC_02373) FROM BACTEROIDES CACCAE ATCC 43185 AT 2.05 A RESOLUTION | PF14717 FAMILY PROTEIN, DUF4465, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
1f0r:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH RPR208815 | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
4yhj:B (THR186) to (GLN219) STRUCTURE AND FUNCTION OF THE HYPERTENSION VARIANT A486V OF G PROTEIN- COUPLED RECEPTOR KINASE 4 (GRK4) | TRANSFERASE
1f0s:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH RPR208707 | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
1f0t:A (GLN30) to (SER54) BOVINE TRYPSIN COMPLEXED WITH RPR131247 | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
4yhq:A (GLY40) to (GLY78) CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT CLINICAL ISOLATE PR20 WITH GRL-5010A | HIV PROTEASE, MUTANT, DRUG RESISTANT, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2e4h:A (GLY255) to (PRO274) SOLUTION STRUCTURE OF CYTOSKELETAL PROTEIN IN COMPLEX WITH TUBULIN TAIL | NMR, CYTOSKELETON, CAP-GLY, COMPLEX STRUCTURE, TUBULIN, SOLUTION STRUCTURE, CLIP, STRUCTURAL PROTEIN
2e4m:C (LEU86) to (TRP112) CRYSTAL STRUCTURE OF HEMAGGLUTININ SUBCOMPONENT COMPLEX (HA- 33/HA-17) FROM CLOSTRIDIUM BOTULINUM SEROTYPE D STRAIN 4947 | CLOSTRIDIUM BOTULINUM, BOTULINUM TOXIN, HEMAGGLUTININ SUBCOMPONENT COMPLEX
1qqu:A (GLN30) to (SER54) CRYSTAL STRUCTURE OF PORCINE BETA TRYPSIN WITH BOUND ACETATE ION | SERINE PROTEASE, HYDROLASE
1qr3:E (GLN30) to (THR54) STRUCTURE OF PORCINE PANCREATIC ELASTASE IN COMPLEX WITH FR901277, A NOVEL MACROCYCLIC INHIBITOR OF ELASTASES AT 1.6 ANGSTROM RESOLUTION | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2uuj:B (GLN30) to (THR54) THROMBIN-HIRUGEN-GW473178 TERNARY COMPLEX AT 1.32A RESOLUTION | BLOOD CLOTTING, GLYCOPROTEIN, SERINE PROTEASE, SERINE PROTEASE INHIBITOR, HIRUGEN, ZYMOGEN, THROMBIN, PROTEASE, SULFATION, HIGH RESOLUTION, SERINE PROTEINASE, BLOOD COAGULATION, PROTEASE INHIBITOR, NON-COVALENT ACTIVE SITE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2uuk:B (GLN30) to (THR54) THROMBIN-HIRUGEN-GW420128 TERNARY COMPLEX AT 1.39A RESOLUTION | BLOOD CLOTTING, GLYCOPROTEIN, SERINE PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, THROMBIN, SERINE PROTEASE INHIBITOR, HIRUGEN, ZYMOGEN, PROTEASE, SULFATION, HIGH RESOLUTION, SERINE PROTEINASE, BLOOD COAGULATION, PROTEASE INHIBITOR, NON-COVALENT ACTIVE SITE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2e74:C (ASP100) to (PRO130) CRYSTAL STRUCTURE OF THE CYTOCHROME B6F COMPLEX FROM M.LAMINOSUS | PHOTOSYNTHESIS, CYTOCHROME F, RIESKE IRON-SULFUR PROTEIN, HEME CN
2e74:D (GLY76) to (ALA106) CRYSTAL STRUCTURE OF THE CYTOCHROME B6F COMPLEX FROM M.LAMINOSUS | PHOTOSYNTHESIS, CYTOCHROME F, RIESKE IRON-SULFUR PROTEIN, HEME CN
2e75:C (ASP100) to (PRO130) CRYSTAL STRUCTURE OF THE CYTOCHROME B6F COMPLEX WITH 2-NONYL-4- HYDROXYQUINOLINE N-OXIDE (NQNO) FROM M.LAMINOSUS | PHOTOSYNTHESIS, CYTOCHROME F, RIESKE IRON-SULFUR PROTEIN, HEME CN
2e76:C (ASP100) to (PRO130) CRYSTAL STRUCTURE OF THE CYTOCHROME B6F COMPLEX WITH TRIDECYL- STIGMATELLIN (TDS) FROM M.LAMINOSUS | PHOTOSYNTHESIS, CYTOCHROME F, RIESKE IRON-SULFUR PROTEIN, HEME CN
2e76:D (GLY76) to (ALA106) CRYSTAL STRUCTURE OF THE CYTOCHROME B6F COMPLEX WITH TRIDECYL- STIGMATELLIN (TDS) FROM M.LAMINOSUS | PHOTOSYNTHESIS, CYTOCHROME F, RIESKE IRON-SULFUR PROTEIN, HEME CN
4yl2:D (ALA73) to (MET91) AEROCOCCUS VIRIDANS L-LACTATE OXIDASE Y191F MUTANT | FLAVIN, OXIDASE, TIM BARREL, OXIDOREDUCTASE
2e89:A (GLY294) to (VAL317) CRYSTAL STRUCTURE OF AQUIFEX AEOLICUS TILS IN A COMPLEX WITH ATP, MAGNESIUM ION, AND L-LYSINE | ROSSMANN-FOLD, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LIGASE
1qun:I (LYS130) to (GLU154) X-RAY STRUCTURE OF THE FIMC-FIMH CHAPERONE ADHESIN COMPLEX FROM UROPATHOGENIC E.COLI | CHAPERONE ADHESIN DONOR STRAND COMPLEMENTATION, CHAPERONE/STRUCTURAL PROTEIN COMPLEX
1qun:K (LEU131) to (GLU154) X-RAY STRUCTURE OF THE FIMC-FIMH CHAPERONE ADHESIN COMPLEX FROM UROPATHOGENIC E.COLI | CHAPERONE ADHESIN DONOR STRAND COMPLEMENTATION, CHAPERONE/STRUCTURAL PROTEIN COMPLEX
1qun:M (LYS130) to (GLU154) X-RAY STRUCTURE OF THE FIMC-FIMH CHAPERONE ADHESIN COMPLEX FROM UROPATHOGENIC E.COLI | CHAPERONE ADHESIN DONOR STRAND COMPLEMENTATION, CHAPERONE/STRUCTURAL PROTEIN COMPLEX
1qun:O (LEU131) to (GLU154) X-RAY STRUCTURE OF THE FIMC-FIMH CHAPERONE ADHESIN COMPLEX FROM UROPATHOGENIC E.COLI | CHAPERONE ADHESIN DONOR STRAND COMPLEMENTATION, CHAPERONE/STRUCTURAL PROTEIN COMPLEX
3h7o:B (VAL16) to (THR41) CRYSTAL STRUCTURE OF SCABIES MITE INACTIVATED PROTEASE PARALOGUE S-I1 (SMIPP-S-I1) | HYDROLASE
3h7t:A (ASP188) to (LEU215) CRYSTAL STRUCTURE OF SCABIES MITE INACTIVATED PROTEASE PARALOGUE S-D1 (SMIPP-S-D1) | HYDROLASE
3h7t:B (ASP188) to (LEU215) CRYSTAL STRUCTURE OF SCABIES MITE INACTIVATED PROTEASE PARALOGUE S-D1 (SMIPP-S-D1) | HYDROLASE
3h8o:A (LYS111) to (PRO133) STRUCTURE DETERMINATION OF DNA METHYLATION LESIONS N1-MEA AND N3-MEC IN DUPLEX DNA USING A CROSS-LINKED HOST-GUEST SYSTEM | PROTEIN-DNA COMPLEX, DIOXYGENASE, DNA DAMAGE, DNA REPAIR, IRON, METAL-BINDING, NUCLEUS, OXIDOREDUCTASE, OXIDOREDUCTASE-DNA COMPLEX
1qwf:A (GLU30) to (TYR55) C-SRC SH3 DOMAIN COMPLEXED WITH LIGAND VSL12 | SRC SH3 DOMAIN, CLASS I LIGAND COMPLEX, COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) COMPLEX
4jtn:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE AT PH 8.0 IN THE PRESENCE OF DITHIONITE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, CYTOSOL, OXIDOREDUCTASE
2eae:A (THR865) to (LYS895) CRYSTAL STRUCTURE OF 1,2-A-L-FUCOSIDASE FROM BIFIDOBACTERIUM BIFIDUM IN COMPLEXES WITH PRODUCTS | FUCOSIDASE, GLYCOSIDE HYDROLASE
1f6a:A (LYS6) to (PHE40) STRUCTURE OF THE HUMAN IGE-FC BOUND TO ITS HIGH AFFINITY RECEPTOR FC(EPSILON)RI(ALPHA) | IMMUNOGLOBULIN FOLD, GLYCOPROTEIN, RECEPTOR, IGE-BINDING PROTEIN, IGE ANTIBODY, IGE-FC, IMMUNE SYSTEM
3hay:A (LEU289) to (PHE327) CRYSTAL STRUCTURE OF A SUBSTRATE-BOUND FULL H/ACA RNP FROM PYROCOCCUS FURIOSUS | H/ACA, GUIDE RNA, RNA-PROTEIN COMPLEX, PSEUDOURIDINE SYNTHASE, ISOMERASE, TRNA PROCESSING, RIBONUCLEOPROTEIN, RIBOSOME BIOGENESIS, RRNA PROCESSING, RIBOSOMAL PROTEIN, RNA-BINDING, ISOMERASE/BIOSYNTHETIC PROTEIN/RNA COMPLEX
3u53:B (ARG4) to (PRO40) CRYSTAL STRUCTURE OF HUMAN AP4A HYDROLASE | HYDROLASE
3u53:C (ARG4) to (PRO40) CRYSTAL STRUCTURE OF HUMAN AP4A HYDROLASE | HYDROLASE
3u53:D (ARG4) to (PRO40) CRYSTAL STRUCTURE OF HUMAN AP4A HYDROLASE | HYDROLASE
3u57:A (GLY482) to (ASP502) STRUCTURES OF ALKALOID BIOSYNTHETIC GLUCOSIDASES DECODE SUBSTRATE SPECIFICITY | ALKALOID GLUCOSIDASES, HYDROLASE
3u57:B (GLY482) to (ASP502) STRUCTURES OF ALKALOID BIOSYNTHETIC GLUCOSIDASES DECODE SUBSTRATE SPECIFICITY | ALKALOID GLUCOSIDASES, HYDROLASE
1f9i:A (PHE92) to (ARG124) CRYSTAL STRUCTURE OF THE PHOTOACTIVE YELLOW PROTEIN MUTANT Y42F | PHOTORECEPTOR, LIGHT-SENSOR FOR NEGATIVE PHOTOTAXIS, SIGNALING PROTEIN
3u69:H (GLN335) to (LEU359) UNLIGANDED WILD-TYPE HUMAN THROMBIN | HYDROLASE
4jx3:A (TYR38) to (GLU70) CRYSTAL STRUCTURE OF PIM1 KINASE | HUMAN PROTEIN KINASES, SERINE/THREONINE-PROTEIN KINASE, ATP BINDING, PHOSPHORYLATION, TRANSFERASE
1far:A (THR138) to (HIS173) RAF-1 CYSTEINE RICH DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE | TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, PROTO- ONCOGENE, ZINC, ATP-BINDING, PHORBOL-ESTER BINDING, SERINE/THREONINE PROTEIN KINASE COMPLEX
2uwo:A (GLN30) to (THR54) SELECTIVE AND DUAL ACTION ORALLY ACTIVE INHIBITORS OF THROMBIN AND FACTOR XA | TARGET HOPPING, SERINE PROTEASE, EGF-LIKE DOMAIN, POLYMORPHISM, GLYCOPROTEIN, HYDROXYLATION, CALCIUM, ZYMOGEN, COMPLEX, PROTEASE, HYDROLASE, BLOOD COAGULATION, GAMMA- CARBOXYGLUTAMIC ACID, CLEAVAGE ON PAIR OF BASIC RESIDUES
1fb7:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF AN IN VIVO HIV-1 PROTEASE MUTANT IN COMPLEX WITH SAQUINAVIR: INSIGHTS INTO THE MECHANISMS OF DRUG RESISTANCE | HIV PROTEASE, MUTANT, DRUG RESISTANCE, VIRAL PROTEIN, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
2ehr:A (GLY30) to (LEU76) SOLUTION STRUCTURE OF THE SIXTH PDZ DOMAIN OF HUMAN INAD- LIKE PROTEIN | PDZ DOMAIN, INAD-LIKE PROTEIN, INADL PROTEIN, HINADL, PALS1- ASSOCIATED TIGHT JUNCTION PROTEIN, PROTEIN ASSOCIATED TO TIGHT JUNCTIONS, INADL, PATJ, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL PROTEIN
4jyt:A (GLN30) to (SER54) CRYSTAL STRUCTURE OF MATRIPTASE IN COMPLEX WITH INHIBITOR | MATRIPTASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3u8o:H (GLN335) to (LEU359) HUMAN THROMBIN COMPLEXED WITH D-PHE-PRO-D-ARG-D-THR | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3u8r:H (GLN335) to (THR360) HUMAN THROMBIN COMPLEXED WITH D-PHE-PRO-D-ARG-ILE | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3u98:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH MI001 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, HIRUDIN, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3hgu:A (LEU268) to (ASP298) STRUCTURE OF PHENAZINE ANTIBIOTIC BIOSYNTHESIS PROTEIN | PHENAZINE, ANTIBIOTIC, BIOSYNTHETIC PROTEIN
3hgv:A (GLY269) to (ASP298) STRUCTURE OF PHENAZINE ANTIBIOTIC BIOSYNTHESIS PROTEIN | PHENAZINE, ANTIBIOTIC, BIOSYNTHETIC PROTEIN
4yni:A (ARG57) to (SER84) IRON FREE SUCCINATE BOUND RAT CYSTEINE DIOXYGENASE | NON-HEME MONO-IRON, CUPIN, SUCCINATE, IRON FREE, OXIDOREDUCTASE
4yno:A (GLY8) to (GLY32) CRYSTAL STRUCTURE OF MAPK13 AT INACTIVE FORM | P38 KINASE, TRANSFERASE
4yo1:A (TYR138) to (ASP182) STRUCTURE OF LEGIONELLA PNEUMOPHILA DEGQ (DELTA PDZ2 VARIANT) | BACTERIAL PROTEINS, LEGIONELLA, MODELS, MOLECULAR, PEPTIDE HYDROLASES, PROTEIN CONFORMATION, HYDROLASE, CHAPERONE
3ubd:A (GLU69) to (LYS103) STRUCTURE OF N-TERMINAL DOMAIN OF RSK2 KINASE IN COMPLEX WITH FLAVONOID GLYCOSIDE SL0101 | KINASE-INHIBITOR COMPLEX, INDUCED FIT, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1r5u:K (LYS18) to (HIS40) RNA POLYMERASE II TFIIB COMPLEX | ZINC RIBBON, TRANSCRIPTION
1fi8:A (TYR29) to (THR54) RAT GRANZYME B [N66Q] COMPLEXED TO ECOTIN [81-84 IEPD] | COMPLEX (SERINE PROTEASE/INHIBITOR), PROTEASE SUBSTRATE INTERACTIONS, BETA STRAND STRUCTURE, CHYMOTRYPSIN FOLD, GRANZYME B, ECOTIN, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1fi8:B (TYR29) to (THR54) RAT GRANZYME B [N66Q] COMPLEXED TO ECOTIN [81-84 IEPD] | COMPLEX (SERINE PROTEASE/INHIBITOR), PROTEASE SUBSTRATE INTERACTIONS, BETA STRAND STRUCTURE, CHYMOTRYPSIN FOLD, GRANZYME B, ECOTIN, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
4k1s:A (GLY17) to (LEU35) GLY-SER-SPLB PROTEASE FROM STAPHYLOCOCCUS AUREUS AT 1.96 A RESOLUTION | CHYMOTRYPSIN-LIKE FOLD, SERINE PROTEASE, EXTRACELLULAR, HYDROLASE
2eq7:A (THR110) to (ARG131) CRYSTAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM THERMUS THERMOPHILUS HB8 WITH PSBDO | PROTEIN-PROTEIN COMPLEX, OXIDOREDUCTASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2eq7:B (THR110) to (ARG131) CRYSTAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM THERMUS THERMOPHILUS HB8 WITH PSBDO | PROTEIN-PROTEIN COMPLEX, OXIDOREDUCTASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
3hi7:B (ARG95) to (SER129) CRYSTAL STRUCTURE OF HUMAN DIAMINE OXIDASE | OXIDOREDUCTASE, COPPER AMINE OXIDASE, TOPAQUINONE, TPQ, DIAMINE OXIDASE, DAO, HUMAN, GLYCOPROTEIN, HEPARIN-BINDING, METAL-BINDING, SECRETED
1fjs:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF THE INHIBITOR ZK-807834 (CI-1031) COMPLEXED WITH FACTOR XA | PROTEIN INHIBITOR COMPLEX, COAGULATION COFACTOR, PROTEASE, BLOOD CLOTTING
3hig:A (ARG95) to (SER129) CRYSTAL STRUCTURE OF HUMAN DIAMINE OXIDASE IN COMPLEX WITH THE INHIBITOR BERENIL | OXIDOREDUCTASE, COPPER AMINE OXIDASE, TOPAQUINONE, TPQ, DIAMINE OXIDASE, DAO, HUMAN, BERENIL, DIMINAZENE, GLYCOPROTEIN, HEPARIN- BINDING, METAL-BINDING, SECRETED
3hii:B (ARG95) to (SER129) CRYSTAL STRUCTURE OF HUMAN DIAMINE OXIDASE IN COMPLEX WITH THE INHIBITOR PENTAMIDINE | OXIDOREDUCTASE, COPPER AMINE OXIDASE, TOPAQUINONE, TPQ, DIAMINE OXIDASE, DAO, HUMAN, PENTAMIDINE, GLYCOPROTEIN, HEPARIN-BINDING, METAL-BINDING, SECRETED
4k3d:H (GLY100) to (SER101) CRYSTAL STRUCTURE OF BOVINE ANTIBODY BLV1H12 WITH ULTRALONG CDR H3 | IMMUNOGLOBULIN, CYSTINE KNOT, IMMUNE RECOGNITION, IMMUNE SYSTEM
1fn6:A (GLN30) to (ALA55) CRYSTAL STRUCTURE OF PORCINE BETA TRYPSIN WITH 0.1% POLYDOCANOL | SERINE PROTEASE, HYDROLASE
3uej:B (SER230) to (HIS269) STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF AN ANESTHETIC BINDING SITE IN THE SECOND CYSTEINE-RICH DOMAIN OF PROTEIN KINASE CDELTA | PROTEINE KINASE CDELTA, PHOSPHOTRANSFERASE, ANESTHETIC BINDING SITE, METAL BINDING PROTEIN
1fni:A (GLN30) to (SER54) CRYSTAL STRUCTURE OF PORCINE BETA TRYPSIN WITH 0.01% POLYDOCANOL | SERINE PROTEASE, HYDROLASE
3uey:B (SER230) to (HIS269) STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF AN ANESTHETIC BINDING SITE IN THE SECOND CYSTEINE-RICH DOMAIN OF PROTEIN KINASE CDELTA | PROTEINE KINASE CDELTA, PHOSPHOTRANSFERASE, ANESTHETIC BINDING SITE, METAL BINDING PROTEIN
4ysf:A (ARG57) to (SER84) RESTING STATE OF RAT CYSTEINE DIOXYGENASE H155N VARIANT | CUPIN, CROSSLINK, OXIDOREDUCTASE
3hkj:B (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN THROMBIN MUTANT W215A/E217A IN COMPLEX WITH THE EXTRACELLULAR FRAGMENT OF HUMAN PAR1 | SERINE PROTEASE, ACUTE PHASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, DISULFIDE BOND, GAMMA- CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, KRINGLE, PROTEASE, SECRETED, ZYMOGEN, CELL MEMBRANE, G-PROTEIN COUPLED RECEPTOR, MEMBRANE, PHOSPHOPROTEIN, RECEPTOR, TRANSDUCER, TRANSMEMBRANE
1fon:B (GLN13) to (VAL39) CRYSTAL STRUCTURE OF BOVINE PROCARBOXYPEPTIDASE A-S6 SUBUNIT III, A HIGHLY STRUCTURED TRUNCATED ZYMOGEN E | TRUNCATED ZYMOGEN E, SERINE PROTEASE
3ugi:B (SER230) to (HIS269) STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF AN ANESTHETIC BINDING SITE IN THE SECOND CYSTEINE-RICH DOMAIN OF PROTEIN KINASE C DELTA | PROTEINE KINASE C DELTA, PHOSPHOTRANSFERASE, ANESTHETIC BINDING SITE, METAL BINDING PROTEIN
3ugl:A (SER230) to (HIS269) STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF AN ANESTHETIC BINDING SITE IN THE SECOND CYSTEINE-RICH DOMAIN OF PROTEIN KINASE C DELTA | PROTEINE KINASE C DELTA, PHOSPHOTRANSFERASE, ANESTHETIC BINDING SITE, METAL BINDING PROTEIN
3uh1:A (THR293) to (HIS320) CRYSTAL STRUCTURE OF SACCHAROPINE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE WITH BOUND SACCHAROPINE AND NADH | ENZYME MECHANISMS, LYSINE BIOSYNTHESIS, PROTON SHUTTLE, SACCHAROPINE AND NAD BINDING, OXIDOREDUCTASE
3uha:A (THR293) to (ASP319) CRYSTAL STRUCTURE OF SACCHAROPINE DEHYDROGENASE FROM SACCHAROMYCES CERVISIAE COMPLEXED WITH NAD. | LYSINE BIOSYNTHESIS, PROTON SHUTTLE, ENZYME MECHANISM, NAD BINDING, OXIDOREDUCTASE
3uha:B (THR293) to (SER317) CRYSTAL STRUCTURE OF SACCHAROPINE DEHYDROGENASE FROM SACCHAROMYCES CERVISIAE COMPLEXED WITH NAD. | LYSINE BIOSYNTHESIS, PROTON SHUTTLE, ENZYME MECHANISM, NAD BINDING, OXIDOREDUCTASE
4k73:A (VAL127) to (GLY173) X-RAY CRYSTAL STRUCTURE OF AN L,D-TRANSPEPTIDASE FROM MYCOBACTERIUM TUBERCULOSIS H37RV | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, L,D-TRANSPEPTIDASE, TRANSPEPTIDASE, TRANSFERASE
2f08:B (ASP4) to (GLY23) CRYSTAL STRUCTURE OF A MAJOR HOUSE DUST MITE ALLERGEN, DERF 2 | IMMUNOGLOBULIN FOLD, IMMUNE SYSTEM
2v91:A (GLU306) to (TYR333) STRUCTURE OF STRICTOSIDINE SYNTHASE IN COMPLEX WITH STRICTOSIDINE | ALKALOID METABOLISM, SIX BLADED BETA PROPELLER FOLD, STR1, LYASE, VACUOLE, SYNTHASE, GLYCOPROTEIN
4yvc:A (GLY193) to (ASP232) ROCK 1 BOUND TO THIAZOLE INHIBITOR | KINASE, DIMER, DIMERIZATION, MYOSIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1ri5:A (TYR194) to (PHE227) STRUCTURE AND MECHANISM OF MRNA CAP (GUANINE N-7) METHYLTRANSFERASE | METHYLTRANSFERASE, RNA, CAP, M7G, MESSENGER RNA CAP, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
1ri6:A (SER2) to (LEU30) STRUCTURE OF A PUTATIVE ISOMERASE FROM E. COLI | ISOMERASE, 7-BLADED PROPELLER, ENZYME, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
1fuj:C (MET30) to (THR54) PR3 (MYELOBLASTIN) | HYDROLASE, SERINE PROTEASE, GLYCOPROTEIN, ZYMOGEN, HYDROLASE (SERINE PROTEASE)
2f2u:A (GLY209) to (ASP248) CRYSTAL STRUCTURE OF THE RHO-KINASE KINASE DOMAIN | ENZYME-INHIBITOR COMPLEX, TRANSFERASE
1fv2:A (LYS1174) to (GLY1210) THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH AN ANALOGUE OF ITS GANGLIOSIDE RECEPTOR GT1B | TOXIN, CARBOHYDRATE, GANGLIOSIDE, MULTI-VALENT BINDING, RECEPTOR
1fv3:A (LYS1174) to (GLY1210) THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH AN ANALOGUE OF ITS GANGLIOSIDE RECEPTOR GT1B | TOXIN, CARBOHYDRATE, GANGLIOSIDE, MULTI-VALENT BINDING, RECEPTOR
4kab:A (ARG421) to (CYS456) FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 3-METHYL-1,4- DIHYDRO-PYRAZOLO[4,5-C]PYRAZOLE | TYROSINE PROTEIN KINASE, TRANSFERASE, ATP BINDING, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4kab:B (ARG421) to (CYS456) FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 3-METHYL-1,4- DIHYDRO-PYRAZOLO[4,5-C]PYRAZOLE | TYROSINE PROTEIN KINASE, TRANSFERASE, ATP BINDING, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4kao:B (ARG421) to (ASN458) FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 1-(5-TERT- BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-(4-PYRIDIN-3- YL-PHENYL)-UREA | TYROSINE PROTEIN KINASE, TRANSFERASE,ATP BINDING, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2vbv:A (ILE80) to (PRO111) RIBOFLAVIN KINASE MJ0056 FROM METHANOCALDOCOCCUS JANNASCHII IN COMPLEX WITH CDP AND FMN | TRANSFERASE, CRADLE-LOOP BARREL, CTP-DEPENDENT KINASE, FMN
2vbv:B (ILE80) to (PRO111) RIBOFLAVIN KINASE MJ0056 FROM METHANOCALDOCOCCUS JANNASCHII IN COMPLEX WITH CDP AND FMN | TRANSFERASE, CRADLE-LOOP BARREL, CTP-DEPENDENT KINASE, FMN
4yy8:A (PRO443) to (THR474) CRYSTAL STRUCTURE ANALYSIS OF KELCH PROTEIN FROM PLASMODIUM FALCIPARUM | STRUCTURAL GENOMICS CONSORTIUM, SGC, PUTATIVE KELCH PROTEIN, K13, UNKNOWN FUNCTION
1rp1:A (ALA418) to (THR447) DOG PANCREATIC LIPASE RELATED PROTEIN 1 | HYDROLASE, LIPID DEGRADATION, PANCREATIC LIPASE
2f7d:A (VAL164) to (ASN192) A MUTANT RABBIT CATHEPSIN K WITH A NITRILE INHIBITOR | PAPAIN CYSTEINE PROTEASE, HYDROLASE
4yzb:B (ARG27) to (SER60) CDPK1 FROM EIMERIA TENELLA IN COMPLEX WITH INHIBITOR UW1521 | SERINE/THREONINE PROTEIN KINASE, TRANSFERASE, CALCIUM-BINDING, ATP- BINDING, BUMPED KINASE INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4yzm:B (GLU1025) to (LEU1057) HUMANIZED ROCO4 BOUND TO LRRK2-IN1 | ROCO-PROTEIN, KINASE, LRRK2, INHIBITOR, TRANSFERASE
1rrl:A (SER57) to (GLU104) SOYBEAN LIPOXYGENASE (LOX-3) AT 93K AT 2.0 A RESOLUTION | OXIDOREDUCTASE, IRON METALLOPROTEIN, LIPOXYGENASE
1rrl:B (SER57) to (GLU104) SOYBEAN LIPOXYGENASE (LOX-3) AT 93K AT 2.0 A RESOLUTION | OXIDOREDUCTASE, IRON METALLOPROTEIN, LIPOXYGENASE
1rtf:B (GLN30) to (LEU53) COMPLEX OF BENZAMIDINE WITH THE CATALYTIC DOMAIN OF HUMAN TWO CHAIN TISSUE PLASMINOGEN ACTIVATOR [(TC)-T-PA] | SERINE PROTEASE, FIBRINOLYTIC ENZYMES
1g2l:A (GLN30) to (THR54) FACTOR XA INHIBITOR COMPLEX | BLOOD COAGULATION, FACTOR XA, INHIBITOR COMPLEXES, SERINE PROTEINASE, BLOOD COAGULATION CASCADE, HYDROLASE
1g36:A (GLN30) to (SER54) TRYPSIN INHIBITOR COMPLEX | BLOOD COAGULATION, FACTOR XA, INHIBITOR COMPLEXES, SERINE PROTEINASE, BLOOD COAGULATION CASCADE, HYDROLASE
1rv7:A (ARG8) to (GLU34) CRYSTAL STRUCTURES OF A MULTIDRUG-RESISTANT HIV-1 PROTEASE REVEAL AN EXPANDED ACTIVE SITE CAVITY | HIV PROTEASE, AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, MULTI-DRUG RESISTANCE, LOPINAVIR
3uns:A (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEPHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, PROTEIN BINDING, DUODENUM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1g43:A (LYS76) to (ARG120) CRYSTAL STRUCTURE OF A FAMILY IIIA CBD FROM CLOSTRIDIUM CELLULOLYTICUM | BETA-SANDWICH, STRUCTURAL PROTEIN
3uo4:A (ASP132) to (LEU164) AURORA A IN COMPLEX WITH RPM1680 | PROTEIN KINASE, AURORA A, INHIBITOR, DFG-IN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3uo5:A (ASP132) to (PHE165) AURORA A IN COMPLEX WITH YL1-038-31 | PROTEIN KINASE, AURORA A, INHIBITOR, DFG-IN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1rwm:A (SER236) to (ASN259) CRYSTAL STRUCTURE OF HUMAN CASPASE-1 IN COMPLEX WITH 4-OXO-3-[2-(5- {[4-(QUINOXALIN-2-YLAMINO)-BENZOYLAMINO]-METHYL}-THIOPHEN-2-YL)- ACETYLAMINO]-PENTANOIC ACID | PROTEIN-SMALL MOLECULE INHIBITOR COMPLEX, HYDROLASE
1g6l:A (PRO1009) to (GLU1034) 1.9A CRYSTAL STRUCTURE OF TETHERED HIV-1 PROTEASE | HYDROLASE
4kh6:B (SER527) to (ASN551) TOXOPLASMA GONDII NTPDASE1 C258S/C268S E493G CRYSTALLIZED WITH MG AND AMPNP | HYDROLASE, ACTIN-LIKE FOLD, NTPDASE
4kh8:A (HIS87) to (MSE117) CRYSTAL STRUCTURE OF A LIPOCALIN-LIKE PROTEIN (EF0376) FROM ENTEROCOCCUS FAECALIS V583 AT 1.60 A RESOLUTION | LIPOCALIN-LIKE FOLD, TWO DOMAINS, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
2vgb:A (GLY215) to (GLN239) HUMAN ERYTHROCYTE PYRUVATE KINASE | METAL-BINDING, PHOSPHORYLATION, PYRUVATE KINASE IN THE ACTIVE R-STATE, KINASE, PYRUVATE, MAGNESIUM, GLYCOLYSIS, TRANSFERASE, DISEASE MUTATION
3urd:A (ILE7) to (ALA34) T181A MUTANT OF ALPHA-LYTIC PROTEASE | SERINE PROTEASE, HYDROLASE
3urf:Z (LYS6) to (ALA35) HUMAN RANKL/OPG COMPLEX | CYSTEIN-RICH DOMAIN, BETA-SANDWICH, CYTOKINE
2vgg:C (GLY215) to (GLN239) HUMAN ERYTHROCYTE PYRUVATE KINASE: R479H MUTANT | METAL-BINDING, PHOSPHORYLATION, PYRUVATE KINASE IN THE ACTIVE R-STATE, KINASE, PYRUVATE, MAGNESIUM, GLYCOLYSIS, TRANSFERASE, DISEASE MUTATION
2vgg:D (GLY215) to (GLU241) HUMAN ERYTHROCYTE PYRUVATE KINASE: R479H MUTANT | METAL-BINDING, PHOSPHORYLATION, PYRUVATE KINASE IN THE ACTIVE R-STATE, KINASE, PYRUVATE, MAGNESIUM, GLYCOLYSIS, TRANSFERASE, DISEASE MUTATION
3hoy:B (THR1170) to (HIS1195) COMPLETE RNA POLYMERASE II ELONGATION COMPLEX VI | RNA POLYMERASE II, METAL-BINDING, TRANSCRIPTION BUBBLE, ELONGATION COMPLEX, TRANSCRIPTION, DNA-RNA MISMATCH, RNA FRAYING, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, MRNA PROCESSING, TRANSCRIPTION,TRANSFERASE/DNA/RNA HYBRID COMPLEX
4z4t:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 75MM FUCOSE | FUCOSE, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4z4s:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 150MM FUCOSE | FUCOSE, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4z4s:B (GLY332) to (TRP381) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 150MM FUCOSE | FUCOSE, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4z4s:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 150MM FUCOSE | FUCOSE, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4z4u:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 37.5MM FUCOSE | FUCOSE, NOROVIRUS, PROTRUDING DOMAIN,VIRAL PROTEIN
4z4u:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 37.5MM FUCOSE | FUCOSE, NOROVIRUS, PROTRUDING DOMAIN,VIRAL PROTEIN
4z4v:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 19MM FUCOSE | FUCOSE, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4z4w:A (GLY332) to (TRP381) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 4.7MM FUCOSE | FUCOSE, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4z4w:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 4.7MM FUCOSE | FUCOSE, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4z4w:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 4.7MM FUCOSE | FUCOSE, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
2vhe:B (ASP168) to (GLY189) PGLD-COA COMPLEX: AN ACETYL TRANSFERASE FROM CAMPYLOBACTER JEJUNI | COENZYME A, TRANSFERASE, N-ACETYL TRANSFERASE
4z4y:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 7.5MM B ANTIGEN (TRISACCHARIDE) | HBGA, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4z4y:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 7.5MM B ANTIGEN (TRISACCHARIDE) | HBGA, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4z4z:A (GLY332) to (TRP381) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 30MM B ANTIGEN (TRISACCHARIDE) | HBGA, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
2vid:B (GLY17) to (LEU35) SERINE PROTEASE SPLB FROM STAPHYLOCOCCUS AUREUS AT 1.8A RESOLUTION | PROTEASE, SERINE PROTEASE, STAPHYLOCOCCUS AUREUS, HYDROLASE
2fja:A (ARG173) to (ALA207) ADENOSINE 5'-PHOSPHOSULFATE REDUCTASE IN COMPLEX WITH SUBSTRATE | APS REDUCTASE, ADENYLYL-PHOSPHOSULFATE REDUCTASE, SULFUR CYCLE, OXIDOREDUCTASE
2fja:C (ARG2173) to (ALA2207) ADENOSINE 5'-PHOSPHOSULFATE REDUCTASE IN COMPLEX WITH SUBSTRATE | APS REDUCTASE, ADENYLYL-PHOSPHOSULFATE REDUCTASE, SULFUR CYCLE, OXIDOREDUCTASE
2fjb:A (ARG173) to (ALA207) ADENOSINE-5'-PHOSPHOSULFATE REDUCTASE IM COMPLEX WITH PRODUCTS | APS REDUCTASE, SULFUR CYCLE, OXIDOREDUCTASE
2fjb:C (ARG2173) to (ALA2207) ADENOSINE-5'-PHOSPHOSULFATE REDUCTASE IM COMPLEX WITH PRODUCTS | APS REDUCTASE, SULFUR CYCLE, OXIDOREDUCTASE
1g9i:E (GLN30) to (SER54) CRYSTAL STRUCTURE OF BETA-TRYSIN COMPLEX IN CYCLOHEXANE | TRYPSIN-INHIBITOR COMPLEX, ORGANIC MEDIA, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2fjd:A (ARG173) to (ALA207) ADENOSINE-5-PHOSPHOSULFATE REDUCTASE IN COMPLEX WITH SULFITE (COVALENT ADDUCT) | APS REDUCTASE, SULFUR CYCLE, OXIDOREDUCTASE
2fjd:C (ARG2173) to (ALA2207) ADENOSINE-5-PHOSPHOSULFATE REDUCTASE IN COMPLEX WITH SULFITE (COVALENT ADDUCT) | APS REDUCTASE, SULFUR CYCLE, OXIDOREDUCTASE
3hqo:B (ILE147) to (ASP173) CRYSTAL STRUCTURES OF LEISHMANIA MEXICANA PYRUVATE KINASE (LMPYK) IN COMPLEX WITH ATP AND OXALATE | TIM BARREL, R-STATE ENZYME, ALLOSTERIC ENZYME, GLYCOLYSIS, KINASE, MAGNESIUM, METAL-BINDING, PYRUVATE, TRANSFERASE
3hqp:I (ILE147) to (ASP173) CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA PYRUVATE KINASE (LMPYK) IN COMPLEX WITH ATP, OXALATE AND FRUCTOSE 2,6 BISPHOSPHATE | TIM BARREL, T-STATE ENZYME, ALLOSTERIC ENZYME, GLYCOLYSIS, KINASE, MAGNESIUM, METAL-BINDING, PYRUVATE, TRANSFERASE
3hqp:L (ILE147) to (ASP173) CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA PYRUVATE KINASE (LMPYK) IN COMPLEX WITH ATP, OXALATE AND FRUCTOSE 2,6 BISPHOSPHATE | TIM BARREL, T-STATE ENZYME, ALLOSTERIC ENZYME, GLYCOLYSIS, KINASE, MAGNESIUM, METAL-BINDING, PYRUVATE, TRANSFERASE
3uto:B (HIS155) to (MET188) TWITCHIN KINASE REGION FROM C.ELEGANS (FN31-NL-KIN-CRD-IG26) | KINASE, MUSCLE SARCOMERE, TRANSFERASE
1gba:A (ILE31) to (ALA55) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA | ACTIVE-SITE MUTATION, HYDROLASE (SERINE PROTEINASE)
1gbb:A (ILE31) to (ALA55) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gbc:A (ILE31) to (ALA55) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gbd:A (ILE31) to (ALA55) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gbf:A (ILE31) to (ALA55) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gbj:A (ILE31) to (ALA55) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA | ACTIVE-SITE MUTATION, HYDROLASE (SERINE PROTEINASE)
1gbk:A (ILE31) to (ALA55) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gbm:A (ILE31) to (ALA55) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gbt:A (GLN30) to (SER54) STRUCTURE OF AN ACYL-ENZYME INTERMEDIATE DURING CATALYSIS: (GUANIDINOBENZOYL) TRYPSIN | HYDROLASE(SERINE PROTEINASE)
1gcd:A (GLN30) to (THR54) REFINED CRYSTAL STRUCTURE OF "AGED" AND "NON-AGED" ORGANOPHOSPHORYL CONJUGATES OF GAMMA-CHYMOTRYPSIN | HYDROLASE(SERINE PROTEINASE)
1s1n:A (GLU177) to (LEU201) SH3 DOMAIN OF HUMAN NEPHROCYSTIN | BETA BARREL, CELL ADHESION
4z82:A (ARG57) to (SER84) CYSTEINE BOUND RAT CYSTEINE DIOXYGENASE C164S VARIANT AT PH 8.1 | THIOETHER BOND, POST-TRANSLATIONAL MODIFICATION, POST TRANSLATIONAL, POSTTRANSLATIONAL, SUBSTRATE BOUND, OXIDOREDUCTASE
3uwj:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH MI353 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, HIRUDIN, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gg6:B (GLN30) to (THR54) CRYSTAL STUCTURE OF GAMMA CHYMOTRYPSIN WITH N-ACETYL- PHENYLALANINE TRIFLUOROMETHYL KETONE BOUND AT THE ACTIVE SITE | CHYMOTRYPSIN, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
2fns:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE INACTIVE (D25N) HIV-1 PROTEASE COMPLEXED WITH WILD-TYPE HIV-1 NC-P1 SUBSTRATE. | STRUCTURAL INTERMEDIATE, SUBSTRATE RECOGNITION, HIV-1 PROTEASE, NC-P1 SUBSTRATE, DRUG RESISTANCE, FLAP CONFORMATION, HYDROLASE
2fnt:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF A DRUG-RESISTANT (V82A) INACTIVE (D25N) HIV-1 PROTEASE COMPLEXED WITH AP2V VARIANT OF HIV-1 NC-P1 SUBSTRATE. | STRUCTURAL INTERMEDIATE, SUBSTRATE RECOGNITION, HIV-1 PROTEASE, NC-P1 SUBSTRATE, DRUG RESISTANCE, FLAP CONFORMATION, HYDROLASE
1s3x:A (PHE92) to (TYR115) THE CRYSTAL STRUCTURE OF THE HUMAN HSP70 ATPASE DOMAIN | HSP70, ATPASE, MOLECULAR CHAPERONE
2fp8:B (ASN114) to (LEU138) STRUCTURE OF STRICTOSIDINE SYNTHASE, THE BIOSYNTHETIC ENTRY TO THE MONOTERPENOID INDOLE ALKALOID FAMILY | SIX BLADED BETA PROPELLER FOLD, STR1, SYNTHASE, LYASE
3uys:C (ARG8) to (CYS41) CRYSTAL STRUCTURE OF APO HUMAN CK1D | CK1D, KINASE, PF670462, TRANSFERASE
3uyt:D (ARG8) to (CYS41) CRYSTAL STRUCTURE OF CK1D WITH PF670462 FROM P1 CRYSTAL FORM | CK1D, KINASE, INHIBITOR, PF670462, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3uyu:A (GLY68) to (ALA90) STRUCTURAL BASIS FOR THE ANTIFREEZE ACTIVITY OF AN ICE-BINDING PROTEIN (LEIBP) FROM ARCTIC YEAST | RIGHT-HANDED BETA-HELIX FOLD, ICE BINDING PROTEIN, ANTIFREEZE PROTEIN
3uyv:A (GLY68) to (ALA90) CRYSTAL STRUCTURE OF A GLYCOSYLATED ICE-BINDING PROTEIN (LEIBP) FROM ARCTIC YEAST | RIGHT-HANDED BETA-HELIX FOLD, ICE BINDING PROTEIN, ANTIFREEZE PROTEIN
3ht2:A (GLU21) to (PRO51) ZINK CONTAINING POLYKETIDE CYCLASE REMF FROM STREPTOMYCES RESISTOMYCIFICUS | CUPIN FOLD, ZN-BINDING, ANTIBIOTIC BIOSYNTHESIS, RESISTOMYCIN, METALLOPROTEIN, CYCLASE, LYASE
3ht2:C (GLU21) to (PRO51) ZINK CONTAINING POLYKETIDE CYCLASE REMF FROM STREPTOMYCES RESISTOMYCIFICUS | CUPIN FOLD, ZN-BINDING, ANTIBIOTIC BIOSYNTHESIS, RESISTOMYCIN, METALLOPROTEIN, CYCLASE, LYASE
2fqp:D (ALA6) to (GLY31) CRYSTAL STRUCTURE OF A CUPIN DOMAIN (BP2299) FROM BORDETELLA PERTUSSIS TOHAMA I AT 1.80 A RESOLUTION | DOUBLE-STRANDED BETA-HELIX FOLD, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, METAL BINDING PROTEIN
4zc0:B (GLU436) to (MET467) STRUCTURE OF A DODECAMERIC BACTERIAL HELICASE | HELICASE ATPASE DNA REPLICATION, DODECAMER, HYDROLASE
1s5s:A (GLN30) to (SER54) PORCINE TRYPSIN COMPLEXED WITH GUANIDINE-3-PROPANOL INHIBITOR | HYDROLASE, SERINE PROTEASE
4zce:B (GLY52) to (GLY78) CRYSTAL STRUCTURE OF THE DUST MITE ALLERGEN DER P 23 FROM DERMATOPHAGOIDES PTERONYSSINUS | DUST, MITE, ALLERGEN, DER P 23
1s6h:A (GLN30) to (SER54) PORCINE TRYPSIN COMPLEXED WITH GUANIDINE-3-PROPANOL INHIBITOR | HYDROLASE, SERINE PROTEASE
3v0a:B (ASP866) to (ASN891) 2.7 ANGSTROM CRYSTAL STRUCTURE OF BONT/AI IN COMPLEX WITH NTNHA | BOTULINUM NEUROTOXIN, TOXIN, NEUROTOXIN ASSOCIATED PROTEIN, PROGENITOR TOXIN COMPLEX, VHH BOUND INTERLOCKED COMPLEX, NTNHA
4zcn:A (THR67) to (LEU91) CRYSTAL STRUCTURE OF NVPIZZA2-S16S58 | COMPUTATIONAL PROTEIN DESIGN, PERMUTATION, BETA-PROPELLER, SELF- ASSEMBLING
2fsm:X (THR7) to (PRO29) MITOGEN ACTIVATED PROTEIN KINASE P38ALPHA (D176A+F327S) ACTIVATING MUTANT FORM-B | MITOGEN ACTIVATED PROTEIN KINASE, P38, ACTIVE MUTANTS, LIPIDS, MAP KINASE INSERTION, AUTOPHOSPHORYLATION, TRANSFERASE
3hvd:A (GLU267) to (LEU338) THE PROTECTIVE ANTIGEN COMPONENT OF ANTHRAX TOXIN FORMS FUNCTIONAL OCTAMERIC COMPLEXES | BACILLUS ANTHRACIS, ANTHRAX PROTECTIVE ANTIGEN, OCTAMER, XRAY-CRYSTALLOGRAPHY, TRANSPORT PROTEIN, TOXIN
3hvd:B (ASN268) to (ASP335) THE PROTECTIVE ANTIGEN COMPONENT OF ANTHRAX TOXIN FORMS FUNCTIONAL OCTAMERIC COMPLEXES | BACILLUS ANTHRACIS, ANTHRAX PROTECTIVE ANTIGEN, OCTAMER, XRAY-CRYSTALLOGRAPHY, TRANSPORT PROTEIN, TOXIN
3hvd:D (ASN268) to (ASP335) THE PROTECTIVE ANTIGEN COMPONENT OF ANTHRAX TOXIN FORMS FUNCTIONAL OCTAMERIC COMPLEXES | BACILLUS ANTHRACIS, ANTHRAX PROTECTIVE ANTIGEN, OCTAMER, XRAY-CRYSTALLOGRAPHY, TRANSPORT PROTEIN, TOXIN
3hvd:F (ASN268) to (ASP335) THE PROTECTIVE ANTIGEN COMPONENT OF ANTHRAX TOXIN FORMS FUNCTIONAL OCTAMERIC COMPLEXES | BACILLUS ANTHRACIS, ANTHRAX PROTECTIVE ANTIGEN, OCTAMER, XRAY-CRYSTALLOGRAPHY, TRANSPORT PROTEIN, TOXIN
3hvd:H (ASN268) to (ASP335) THE PROTECTIVE ANTIGEN COMPONENT OF ANTHRAX TOXIN FORMS FUNCTIONAL OCTAMERIC COMPLEXES | BACILLUS ANTHRACIS, ANTHRAX PROTECTIVE ANTIGEN, OCTAMER, XRAY-CRYSTALLOGRAPHY, TRANSPORT PROTEIN, TOXIN
1ghy:H (GLN30) to (THR54) A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE | THREE-CENTERED, VERY SHORT HYDROGEN BOND, OXYANION HOLE WATER, SHIFT OF PKA OF HIS57, STRUCTURE-BASED DRUG DESIGN, SPECIFICITY, UROKINASE, TRYPSIN, THROMBIN, ZN+2-MEDIATED INHIBITION, BLOOD CLOTTING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ghv:H (GLN30) to (THR54) A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE | THREE-CENTERED, VERY SHORT HYDROGEN BOND, OXYANION HOLE WATER, SHIFT OF PKA OF HIS57, STRUCTURE-BASED DRUG DESIGN, SPECIFICITY, UROKINASE, TRYPSIN, THROMBIN, ZN+2-MEDIATED INHIBITION, BLOOD CLOTTING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ghw:H (GLN30) to (THR54) A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE | THREE-CENTERED, VERY SHORT HYDROGEN BOND, OXYANION HOLE WATER, SHIFT OF PKA OF HIS57, STRUCTURE-BASED DRUG DESIGN, SPECIFICITY, UROKINASE, TRYPSIN, THROMBIN, ZN+2-MEDIATED INHIBITION, BLOOD CLOTTING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1s81:A (GLN30) to (SER54) PORCINE TRYPSIN WITH NO INHIBITOR BOUND | HYDROLASE, SERINE PROTEASE
1s83:A (GLN30) to (SER54) PORCINE TRYPSIN COMPLEXED WITH 4-AMINO PROPANOL | HYDROLASE, SERINE PROTEASE
1s85:A (GLN30) to (SER54) PORCINE TRYPSIN COMPLEXED WITH P-HYDROXYMETHYL BENZAMIDINE AND BORATE | HYDROLASE, SERINE PROTEASE
1gj9:B (PHE30) to (ALA55) ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS | SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN, BLOOD CLOTTING, HYDROLASE
3v12:A (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3v1s:A (GLU306) to (TYR333) SCAFFOLD TAILORING BY A NEWLY DETECTED PICTET-SPENGLERASE AC-TIVITY OF STRICTOSIDINE SYNTHASE (STR1): FROM THE COMMON TRYP-TOLINE SKELETON TO THE RARE PIPERAZINO-INDOLE FRAMEWORK | STRICTOSIDINE SYNTHASE, ALKALOID BIOSYNTHESIS, STRICTOSIDINE SYNTHASE FAMILY, LYASE
1gkn:A (ASN971) to (GLY998) STRUCTURE DETERMINATION AND RATIONAL MUTAGENESIS REVEAL BINDING SURFACE OF IMMUNE ADHERENCE RECEPTOR, CR1 (CD35) | COMPLEMENT, MODULE, SCR, STRUCTURE
1sbg:A (PRO9) to (GLU34) AN ORALLY-BIOAVAILABLE HIV-1 PROTEASE INHIBITOR CONTAINING AN IMIDAZOLE-DERIVED PEPTIDE BOND REPLACEMENT. CRYSTALLOGRAPHIC AND PHARMACOKINETIC ANALYSIS | HYDROLASE(ACID PROTEASE)
1sbx:A (GLU99) to (CYS122) CRYSTAL STRUCTURE OF THE DACHSHUND-HOMOLOGY DOMAIN OF HUMAN SKI | WINGED HELIX, FORKHEAD, ONCOPROTEIN
1gl1:C (GLN30) to (THR54) STRUCTURE OF THE COMPLEX BETWEEN BOVINE ALPHA-CHYMOTRYPSIN AND PMP-C, AN INHIBITOR FROM THE INSECT LOCUSTA MIGRATORIA | HYDROLASE/INHIBITOR, COMPLEX (PROTEASE/INHIBITOR), HYDROLASE, SERINE PROTEASE, SERINE PROTEASE INHIBITOR
4kp0:A (TYR29) to (LEU53) CRYSTAL STRUCTURE OF THE HUMAN CHYMASE WITH TJK002 | HYDROLASE, PROTEASE, SERINE PROTEASE, BENZIMIDAZOLE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
2vlg:A (LEU72) to (VAL113) KINA PAS-A DOMAIN, HOMODIMER | HISTIDINE KINASE, TWO-COMPONENT REGULATORY SYSTEM, TWO-COMPONENT SIGNAL TRANSDUCTION, TRANSFERASE, SPORULATION, PHOSPHORYLATION, SCOD, SCOB, GSIC, SPOIIJ, KINASE, SPOIIF, PAS DOMAIN
2vmf:A (PRO678) to (GLN704) STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES | LINEAR FREE ENERGY RELATIONSHIP, TRANSITION STATE MIMIC, MANNOSIDASE, GLYCOSIDE HYDROLASE, HYDROLASE
1gmw:C (THR15) to (PRO45) STRUCTURE OF UREE | METALLOCHAPERONE, CHAPERONE
1sgc:A (GLU29) to (ALA55) THE 1.8 ANGSTROMS STRUCTURE OF THE COMPLEX BETWEEN CHYMOSTATIN AND STREPTOMYCES GRISEUS PROTEASE A. A MODEL FOR SERINE PROTEASE CATALYTIC TETRAHEDRAL INTERMEDIATES | HYDROLASE (SERINE PROTEINASE), HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1sgf:A (GLY197) to (THR229) CRYSTAL STRUCTURE OF 7S NGF: A COMPLEX OF NERVE GROWTH FACTOR WITH FOUR BINDING PROTEINS (SERINE PROTEINASES) | GROWTH FACTOR (BETA-NGF), HYDROLASE - SERINE PROTEINASE (GAMMA-NGF), INACTIVE SERINE PROTEINASE (ALPHA-NGF), GROWTH FACTOR
1sgf:X (GLY197) to (THR229) CRYSTAL STRUCTURE OF 7S NGF: A COMPLEX OF NERVE GROWTH FACTOR WITH FOUR BINDING PROTEINS (SERINE PROTEINASES) | GROWTH FACTOR (BETA-NGF), HYDROLASE - SERINE PROTEINASE (GAMMA-NGF), INACTIVE SERINE PROTEINASE (ALPHA-NGF), GROWTH FACTOR
2vo5:A (PRO678) to (GLN704) STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES | GLYCOSIDE, HYDROLASE, MANNOSIDASE, TRANSITION STATE MIMIC, LINEAR FREE ENERGY RELATIONSHIP
2voy:F (SER268) to (ARG304) CRYOEM MODEL OF COPA, THE COPPER TRANSPORTING ATPASE FROM ARCHAEOGLOBUS FULGIDUS | HYDROLASEP-TYPE ATPASE, CRYO-EM, HELICAL RECONSTRUCTION, MEMBRANE PROTEIN, COPPER TRANSPORTER, METAL BINDING DOMAIN, HYDROLASE
3i29:B (VAL116) to (ASP145) CRYSTAL STRUCTURE OF A BINARY COMPLEX BETWEEN AN MUTANT TRYPSIN INHIBITOR WITH BOVINE TRYPSIN | P1 AND P2 MUTANT, TRYPSIN INHIBITOR, BOVINE TRYPSIN, COMPLEX, DIGESTION, HYDROLASE, METAL-BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, PROTEASE INHIBITOR, SERINE PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, DISULFIDE BOND
4krz:B (GLY140) to (ASN168) APO CRYSTAL STRUCTURE OF PYRUVATE KINASE (PYK) FROM TRYPANOSOMA CRUZI | TETRAMER, PYRUVATE KINASE, ALLOSTERY, TRANSFERASE
3i2a:A (VAL119) to (ASP148) CRYSTAL STRUCTURE OF A CHIMERIC TRYPSIN INHIBITOR PROTEIN STI(L)- WCI(S) | STI(L)-WCI(S), MUTANT, TRYPSIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR, CHIMERA, DISULFIDE BOND, PROTEASE INHIBITOR, SERINE PROTEASE INHIBITOR, HYDROLASE INHIBITOR
2g2x:B (GLY44) to (HIS101) X-RAY CRYSTAL STRUCTURE PROTEIN Q88CH6 FROM PSEUDOMONAS PUTIDA. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET PPR72. | PPR72, NESG, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, UNKNOWN FUNCTION
2g2x:C (GLY44) to (HIS101) X-RAY CRYSTAL STRUCTURE PROTEIN Q88CH6 FROM PSEUDOMONAS PUTIDA. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET PPR72. | PPR72, NESG, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, UNKNOWN FUNCTION
2vq6:A (LEU7) to (LEU31) TORPEDO CALIFORNICA ACETYLCHOLINESTERASE COMPLEXED WITH 2- PAM | SERINE ESTERASE, ALTERNATIVE SPLICING, NEUROTRANSMITTER DEGRADATION, LIPOPROTEIN, GLYCOPROTEIN, TORPEDO ACHE, CELL JUNCTION, ANTICANCER PRODRUG CPT- 11, SYNAPSE, MEMBRANE, HYDROLASE, GPI-ANCHOR
1slv:B (GLN30) to (SER54) RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; COPPER- BOUND | SERINE PROTEASE, INHIBITOR, COMPLEX, METAL BINDING SITES, PROTEIN ENGINEERING, PROTEASE-SUBSTRATE INTERACTIONS, METALLOPROTEINS, COMPLEX (SERINE PROTEASE-INHIBITOR) COMPLEX
1slw:B (GLN30) to (SER54) RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; NICKEL- BOUND | SERINE PROTEASE, INHIBITOR, COMPLEX, METAL BINDING SITES, PROTEIN ENGINEERING, PROTEASE-SUBSTRATE INTERACTIONS, METALLOPROTEINS, COMPLEX (SERINE PROTEASE-INHIBITOR) COMPLEX
2vrs:B (ALA195) to (THR234) STRUCTURE OF AVIAN REOVIRUS SIGMA C 117-326, C2 CRYSTAL FORM | ALPHA-HELICAL COILED COIL, RECEPTOR-BINDING, TRIPLE BETA-SPIRAL, VIRAL PROTEIN, VIRION, COILED COIL, BETA-BARREL
2vrx:A (ASP92) to (PHE125) STRUCTURE OF AURORA B KINASE IN COMPLEX WITH ZM447439 | SERINE/THREONINE-PROTEIN KINASE, KINASE, NUCLEUS, MITOSIS, MAGNESIUM, CELL CYCLE/TRANSFERASE, CENTROMERE, MICROTUBULE, ATP-BINDING, TRANSFERASE, ANTI-CANCER DRUG TARGET, PHOSPHOPROTEIN, PROTEIN KINASE, NUCLEOTIDE-BINDING, COILED COIL, CELL DIVISION, METAL-BINDING
2g55:A (GLN21) to (SER43) ANOMALOUS SUBSTRUCTURE OF TRYPSIN (P3121) | ANOMALOUS SUBSTRUCTURE OF TRYPSIN (P3121), HYDROLASE
3vb5:B (VAL18) to (PRO39) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH C4Z | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3i4m:B (THR1170) to (HIS1195) 8-OXOGUANINE CONTAINING RNA POLYMERASE II ELONGATION COMPLEX D | RNA POLYMERASE II, METAL-BINDING, TRANSCRIPTION BUBBLE, ELONGATION COMPLEX, TRANSCRIPTION, 8-OXOGUANINE, OXIDATIVE DAMAGE, DNA DAMAGE, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, ZINC-FINGER, DNA REPAIR, MRNA PROCESSING, TRANSCRIPTION,TRANSFERASE-DNA-RNA HYBRID COMPLEX
2vtr:A (ASN3) to (ARG36) IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6- DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT- BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN. | TRANSFERASE, MITOSIS, CELL CYCLE, SERINE/THREONINE PROTEIN KINASE
3i4n:B (THR1170) to (HIS1195) 8-OXOGUANINE CONTAINING RNA POLYMERASE II ELONGATION COMPLEX E | RNA POLYMERASE II, METAL-BINDING, TRANSCRIPTION BUBBLE, ELONGATION COMPLEX, TRANSCRIPTION, 8-OXOGUANINE, DNA DAMAGE, OXIDATIVE DAMAGE, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, ZINC-FINGER, DNA REPAIR, MRNA PROCESSING, TRANSCRIPTION,TRANSFERASE-DNA-RNA HYBRID COMPLEX
2vub:A (PHE3) to (SER38) CCDB, A TOPOISOMERASE POISON FROM E. COLI | CCDB, TOPOISOMERASE POISON, PLASMID
2vub:B (LYS4) to (SER38) CCDB, A TOPOISOMERASE POISON FROM E. COLI | CCDB, TOPOISOMERASE POISON, PLASMID
2vub:G (LYS4) to (ALA37) CCDB, A TOPOISOMERASE POISON FROM E. COLI | CCDB, TOPOISOMERASE POISON, PLASMID
3i56:N (PRO32) to (LEU58) CO-CRYSTAL STRUCTURE OF TRIACETYLOLEANDOMCYIN BOUND TO THE LARGE RIBOSOMAL SUBUNIT | LARGE RIBOSOMAL SUBUNIT, TRIACETYLOLEANDOMCYIN, RIBONUCLEOPROTEIN, RIBOSOMAL PROTEIN, RNA-BINDING, RRNA- BINDING, TRNA-BINDING, METAL-BINDING, ZINC, ZINC-FINGER, ACETYLATION, RIBOSOME, RIBOSOME-ANTIBIOTIC COMPLEX
1gte:B (PHE390) to (ASP424) DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, BINARY COMPLEX WITH 5-IODOURACIL | ELECTRON TRANSFER, FLAVIN, IRON-SULFUR CLUSTERS, PYRIMIDINE CATABOLISM, 5-FLUOROURACIL DEGRADATION, OXIDOREDUCTASE
4kwk:A (ARG57) to (SER84) RAT CYSTEINE DIOXYGENASE WITH CYSTEINE PERSULFIDE BOUND TO ACTIVE SITE IRON | NON-HEME, MONO-IRON, CUPIN, DIOXYGENASE, CYSTEINE-TYROSINE CROSSLINK, OXIDOREDUCTASE
4kwl:A (ARG57) to (SER84) RAT CYSTEINE DIOXYGENASE WITH 3-MERCAPTOPROPIONIC ACID PERSULFIDE BOUND | NON-HEME, MONO-IRON, CUPIN, DIOXYGENASE, CYSTEINE-TYROSINE CROSSLINK, OXIDOREDUCTASE
1sr0:A (THR286) to (GLN310) CRYSTAL STRUCTURE OF SIGNALLING PROTEIN FROM SHEEP(SPS-40) AT 3.0A RESOLUTION USING CRYSTAL GROWN IN THE PRESENCE OF POLYSACCHARIDES | SIGNALLING PROTEIN,INVOLUTION,CRYSTAL STRUCTURE, UNKNOWN FUNCTION
2vvc:A (GLN30) to (THR54) AMINOPYRROLIDINE FACTOR XA INHIBITOR | HYDROLASE, ZYMOGEN, PROTEASE, GLYCOPROTEIN, GAMMA-CARBOXYGLUTAMIC ACID, BLOOD CLOTTING, COAGULATION FACTOR, HYDROXYLATION, SERINE PROTEASE, EGF-LIKE DOMAIN
2vvc:B (GLN30) to (THR54) AMINOPYRROLIDINE FACTOR XA INHIBITOR | HYDROLASE, ZYMOGEN, PROTEASE, GLYCOPROTEIN, GAMMA-CARBOXYGLUTAMIC ACID, BLOOD CLOTTING, COAGULATION FACTOR, HYDROXYLATION, SERINE PROTEASE, EGF-LIKE DOMAIN
1ssx:A (ILE31) to (ALA55) 0.83A RESOLUTION CRYSTAL STRUCTURE OF ALPHA-LYTIC PROTEASE AT PH 8 | A-LYTIC PROTEASE, SERINE PROTEASE, PROTEIN FOLDING, PROTEIN STABILITY, PACKING DISTORTION, HYDROLASE
2vw0:A (GLY361) to (ARG386) CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE | HYDROLASE, SIALIDASE, GLYCOSIDASE, DRUG DESIGN, NEURAMINIDASE, VIRULENCE FACTOR
2vwi:B (ASP16) to (ASN49) STRUCTURE OF THE OSR1 KINASE, A HYPERTENSION DRUG TARGET | KINASE, STE KINASE, HYPERTENSION, TRANSFERASE
2vwl:A (GLN30) to (THR54) AMINOPYRROLIDINE FACTOR XA INHIBITOR | HYDROLASE, CATION, PLASMA, CALCIUM, ZYMOGEN, PROTEASE, INHIBITOR, POLYMORPHISM, GLYCOPROTEIN, GAMMA-CARBOXYGLUTAMIC ACID, BLOOD CLOTTING, COAGULATION FACTOR, HYDROXYLATION, SERINE PROTEASE, EGF-LIKE DOMAIN, CLEAVAGE ON PAIR OF BASIC RESIDUES
2vwm:A (GLN30) to (ALA55) AMINOPYRROLIDINE FACTOR XA INHIBITOR | HYDROLASE, CATION, PLASMA, CALCIUM, ZYMOGEN, PROTEASE, INHIBITOR, POLYMORPHISM, GLYCOPROTEIN, GAMMA-CARBOXYGLUTAMIC ACID, BLOOD CLOTTING, COAGULATION FACTOR, HYDROXYLATION, SERINE PROTEASE, EGF-LIKE DOMAIN, CLEAVAGE ON PAIR OF BASIC RESIDUES
2vwm:B (GLN30) to (THR54) AMINOPYRROLIDINE FACTOR XA INHIBITOR | HYDROLASE, CATION, PLASMA, CALCIUM, ZYMOGEN, PROTEASE, INHIBITOR, POLYMORPHISM, GLYCOPROTEIN, GAMMA-CARBOXYGLUTAMIC ACID, BLOOD CLOTTING, COAGULATION FACTOR, HYDROXYLATION, SERINE PROTEASE, EGF-LIKE DOMAIN, CLEAVAGE ON PAIR OF BASIC RESIDUES
2vwn:A (GLN30) to (THR54) AMINOPYRROLIDINE FACTOR XA INHIBITOR | HYDROLASE, CATION, PLASMA, CALCIUM, ZYMOGEN, PROTEASE, INHIBITOR, POLYMORPHISM, GLYCOPROTEIN, GAMMA-CARBOXYGLUTAMIC ACID, BLOOD CLOTTING, COAGULATION FACTOR, HYDROXYLATION, SERINE PROTEASE, EGF-LIKE DOMAIN, CLEAVAGE ON PAIR OF BASIC RESIDUES
2vwu:A (TYR614) to (LEU649) EPHB4 KINASE DOMAIN INHIBITOR COMPLEX | TYROSINE-PROTEIN KINASE, RECEPTOR TYROSINE KINASE, KINASE, MUTANT, MEMBRANE, RECEPTOR, TRANSFERASE, ATP-BINDING, POLYMORPHISM, GLYCOPROTEIN, TRANSMEMBRANE, PHOSPHOPROTEIN, UNPHOSPHORYLATED, NUCLEOTIDE-BINDING
2vww:A (TYR614) to (LEU649) EPHB4 KINASE DOMAIN INHIBITOR COMPLEX | TYROSINE-PROTEIN KINASE, RECEPTOR TYROSINE KINASE, KINASE, MUTANT, MEMBRANE, RECEPTOR, TRANSFERASE, ATP-BINDING, POLYMORPHISM, GLYCOPROTEIN, TRANSMEMBRANE, PHOSPHOPROTEIN, UNPHOSPHORYLATED, NUCLEOTIDE-BINDING
2vwy:A (TYR614) to (LYS650) EPHB4 KINASE DOMAIN INHIBITOR COMPLEX | TYROSINE-PROTEIN KINASE, RECEPTOR TYROSINE KINASE, KINASE, MUTANT, MEMBRANE, RECEPTOR, TRANSFERASE, ATP-BINDING, POLYMORPHISM, GLYCOPROTEIN, TRANSMEMBRANE, PHOSPHOPROTEIN, UNPHOSPHORYLATED, NUCLEOTIDE-BINDING
2vwz:A (TYR614) to (LYS650) EPHB4 KINASE DOMAIN INHIBITOR COMPLEX | TYROSINE-PROTEIN KINASE, RECEPTOR TYROSINE KINASE, KINASE, MUTANT, MEMBRANE, RECEPTOR, TRANSFERASE, ATP-BINDING, POLYMORPHISM, GLYCOPROTEIN, TRANSMEMBRANE, PHOSPHOPROTEIN, UNPHOSPHORYLATED, NUCLEOTIDE-BINDING
2gch:G (LEU199) to (ALA229) REFINED CRYSTAL STRUCTURE OF GAMMA-CHYMOTRYPSIN AT 1.9 ANGSTROMS RESOLUTION | HYDROLASE (SERINE PROTEINASE)
2gde:H (GLN30) to (THR54) THROMBIN IN COMPLEX WITH INHIBITOR | THROMBIN, COMPLEX STRUCTURE, BLOOD CLOTTING-HYDROLASE INHIBITOR COMPLEX
2vz5:A (PHE31) to (GLN79) STRUCTURE OF THE PDZ DOMAIN OF TAX1 (HUMAN T-CELL LEUKEMIA VIRUS TYPE I) BINDING PROTEIN 3 | WNT SIGNALING PATHWAY, PROTEIN BINDING, NUCLEUS, CYTOPLASM, PDZ DOMAIN
2gg1:A (LYS311) to (ALA346) NMR SOLUTION STRUCTURE OF DOMAIN III OF THE E-PROTEIN OF TICK-BORNE LANGAT FLAVIVIRUS (INCLUDES RDC RESTRAINTS) | VIRAL PROTEIN, NMR, DOMAIN III
3veq:A (VAL719) to (ASP748) A BINARY COMPLEX BETWWEN BOVINE PANCREATIC TRYPSIN AND A ENGINEERED MUTANT TRYPSIN INHIBITOR | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1syt:A (THR286) to (GLN310) CRYSTAL STRUCTURE OF SIGNALLING PROTEIN FROM GOAT SPG-40 IN THE PRESENSE OF N,N',N''-TRIACETYL-CHITOTRIOSE AT 2.6A RESOLUTION | SIGNALLING PROTEIN, GOAT SPG-40, 2.6A RESOLUTION, SIGNALING PROTEIN
1szp:B (THR356) to (GLU389) A CRYSTAL STRUCTURE OF THE RAD51 FILAMENT | HOMOLOGOUS RECOMBINATION, ASYMMETRY, RAD51 FILAMENT, DNA BINDING PROTEIN
3vil:A (SER457) to (GLU478) CRYSTAL STRUCTURE OF BETA-GLUCOSIDASE FROM TERMITE NEOTERMES KOSHUNENSIS IN COMPLEX WITH SALICIN | CELLULASES, GLYCOSYL HYDROLASE, HYDROLASE
3vik:A (SER457) to (GLU478) CRYSTAL STRUCTURE OF BETA-GLUCOSIDASE FROM TERMITE NEOTERMES KOSHUNENSIS IN COMPLEX WITH CELLOBIOSE | CELLULASES, GLYCOSYL HYDROLASE, HYDROLASE
3vim:A (SER457) to (GLU478) CRYSTAL STRUCTURE OF BETA-GLUCOSIDASE FROM TERMITE NEOTERMES KOSHUNENSIS IN COMPLEX WITH A NEW GLUCOPYRANOSIDIC PRODUCT | CELLULASES, GLYCOSYL HYDROLASE, HYDROLASE
1t32:A (TYR29) to (THR54) A DUAL INHIBITOR OF THE LEUKOCYTE PROTEASES CATHEPSIN G AND CHYMASE WITH THERAPEUTIC EFFICACY IN ANIMALS MODELS OF INFLAMMATION | INFLAMMATION INHIBITOR SERINE PROTEASE, HYDROLASE
4zkt:A (LEU19) to (PRO43) CRYSTAL STRUCTURE OF THE PROGENITOR M COMPLEX OF CLOSTRIDIUM BOTULINUM TYPE E NEUROTOXIN | BONT/E-NTNHE HETERO-DIMER, ACIDIC CLUSTER, DOMAIN SWAP, PROGENITOR COMPLEX, HYDROLASE-TOXIN COMPLEX
4zkt:C (LEU19) to (PRO43) CRYSTAL STRUCTURE OF THE PROGENITOR M COMPLEX OF CLOSTRIDIUM BOTULINUM TYPE E NEUROTOXIN | BONT/E-NTNHE HETERO-DIMER, ACIDIC CLUSTER, DOMAIN SWAP, PROGENITOR COMPLEX, HYDROLASE-TOXIN COMPLEX
4zkt:E (LEU19) to (PRO43) CRYSTAL STRUCTURE OF THE PROGENITOR M COMPLEX OF CLOSTRIDIUM BOTULINUM TYPE E NEUROTOXIN | BONT/E-NTNHE HETERO-DIMER, ACIDIC CLUSTER, DOMAIN SWAP, PROGENITOR COMPLEX, HYDROLASE-TOXIN COMPLEX
1h3i:B (THR153) to (PHE193) CRYSTAL STRUCTURE OF THE HISTONE METHYLTRANSFERASE SET7/9 | TRANSFERASE, METHYLTRANSFERASE
2glw:A (ILE37) to (PRO65) THE SOLUTION STRUCTURE OF PHS018 FROM PYROCOCCUS HORIKOSHII | RIFT BARREL, BIOINFORMATICS, TRANSCRIPTION
1t60:D (MET118) to (TRP138) CRYSTAL STRUCTURE OF TYPE IV COLLAGEN NC1 DOMAIN FROM BOVINE LENS CAPSULE | BASEMENT MEMBRANE, TYPE IV COLLAGEN, NC1 DOMAIN, STRUCTURAL PROTEIN
1t60:G (ALA115) to (TRP138) CRYSTAL STRUCTURE OF TYPE IV COLLAGEN NC1 DOMAIN FROM BOVINE LENS CAPSULE | BASEMENT MEMBRANE, TYPE IV COLLAGEN, NC1 DOMAIN, STRUCTURAL PROTEIN
1t60:J (ALA115) to (TRP138) CRYSTAL STRUCTURE OF TYPE IV COLLAGEN NC1 DOMAIN FROM BOVINE LENS CAPSULE | BASEMENT MEMBRANE, TYPE IV COLLAGEN, NC1 DOMAIN, STRUCTURAL PROTEIN
1t60:K (MET116) to (TRP138) CRYSTAL STRUCTURE OF TYPE IV COLLAGEN NC1 DOMAIN FROM BOVINE LENS CAPSULE | BASEMENT MEMBRANE, TYPE IV COLLAGEN, NC1 DOMAIN, STRUCTURAL PROTEIN
1t60:N (ALA115) to (TRP138) CRYSTAL STRUCTURE OF TYPE IV COLLAGEN NC1 DOMAIN FROM BOVINE LENS CAPSULE | BASEMENT MEMBRANE, TYPE IV COLLAGEN, NC1 DOMAIN, STRUCTURAL PROTEIN
1t60:R (VAL113) to (TRP135) CRYSTAL STRUCTURE OF TYPE IV COLLAGEN NC1 DOMAIN FROM BOVINE LENS CAPSULE | BASEMENT MEMBRANE, TYPE IV COLLAGEN, NC1 DOMAIN, STRUCTURAL PROTEIN
1t60:T (MET116) to (TRP138) CRYSTAL STRUCTURE OF TYPE IV COLLAGEN NC1 DOMAIN FROM BOVINE LENS CAPSULE | BASEMENT MEMBRANE, TYPE IV COLLAGEN, NC1 DOMAIN, STRUCTURAL PROTEIN
1t60:W (PHE6) to (TYR28) CRYSTAL STRUCTURE OF TYPE IV COLLAGEN NC1 DOMAIN FROM BOVINE LENS CAPSULE | BASEMENT MEMBRANE, TYPE IV COLLAGEN, NC1 DOMAIN, STRUCTURAL PROTEIN
2goo:F (GLN9) to (ILE48) TERNARY COMPLEX OF BMP-2 BOUND TO BMPR-IA-ECD AND ACTRII-ECD | TGF-BETA, BMP-2, BMPR-IA, ACTRII, ALK-3,, TRANSFERASE
2w27:A (LEU15) to (LEU47) CRYSTAL STRUCTURE OF THE BACILLUS SUBTILIS YKUI PROTEIN, WITH AN EAL DOMAIN, IN COMPLEX WITH SUBSTRATE C-DI-GMP AND CALCIUM | PROTEIN STRUCTURE INITIATIVE, SIGNALING PROTEIN, STRUCTURAL GENOMICS, PSI, MCSG, EAL DOMAIN, YKUI PROTEIN, CYCLIC DI-GMP
2w27:B (LEU15) to (LEU47) CRYSTAL STRUCTURE OF THE BACILLUS SUBTILIS YKUI PROTEIN, WITH AN EAL DOMAIN, IN COMPLEX WITH SUBSTRATE C-DI-GMP AND CALCIUM | PROTEIN STRUCTURE INITIATIVE, SIGNALING PROTEIN, STRUCTURAL GENOMICS, PSI, MCSG, EAL DOMAIN, YKUI PROTEIN, CYCLIC DI-GMP
2w2x:D (LYS7) to (SER37) COMPLEX OF RAC2 AND PLCG2 SPPH DOMAIN | HYDROLASE, PHOSPHOLIPASE C, PHOSPHOINOSITIDES, RHO GTPASES, RAC, SH2 DOMAIN, SH3 DOMAIN, SIGNALING PROTEIN/HYDROLASE
1h7b:A (PRO284) to (ASN318) STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES, NATIVE NRDD | OXIDOREDUCTASE, REDUCTASE, ALLOSTERIC REGULATION, SUBSTRATE SPECIFICITY
1t8u:A (HIS340) to (LEU364) CRYSTAL STRUCTURE OF HUMAN 3-O-SULFOTRANSFERASE-3 WITH BOUND PAP AND TETRASACCHARIDE SUBSTRATE | ALPHA-BETA MOTIF, SUBSTRATE-BINDING CLEFT, TRANSFERASE
4zp5:B (ILE24) to (ASP57) MAP4K4 IN COMPLEX WITH INHIBITOR | KINASE, INHIBITOR, TRANSFERASE-INHIBITOR COMPLEX
4l9p:B (ARG348) to (GLY366) CRYSTAL STRUCTURE OF ASPERGILLUS FUMIGATUS PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE FII ANALOG, FPT-II, AND THE KCVVM PEPTIDE | TERNARY COMPLEX WITH ISOPRENOID AND CAAX PEPTIDE SUBSTRATE, CAAX FARNESYLTRANSFERASE, ISOPRENOID AND CAAX PROTEIN/PEPTIDE SUBSTRATE, TRANSFERASE
3iiq:A (ASN219) to (VAL247) CRYSTALLOGRAPHIC ANALYSIS OF BACTERIAL SIGNAL PEPTIDASE IN TERNARY COMPLEX WITH ARYLOMYCIN A2 AND A BETA-SULTAM INHIBITOR | SER/LYS DYAD, LIPOPEPTIDE, SERINE PROTEASE, BIARYL BRIDGE, MORPHOLINO BETA-SULTAM, ANTIBIOTIC, PEPTIDASE, HYDROLASE-ANTIBIOTIC-INHIBITOR COMPLEX
2w4r:B (TYR587) to (LYS626) CRYSTAL STRUCTURE OF THE REGULATORY DOMAIN OF HUMAN LGP2 | INNATE IMMUNITY, IMMUNE RESPONSE, NUCLEOTIDE-BINDING, COILED COIL, ATP-BINDING, POLYMORPHISM, DOUBLE-STRAND RNA BINDING PROTEIN, HELICASE, HYDROLASE, CYTOPLASM, RNA-BINDING
1h8d:H (GLN30) to (THR54) X-RAY STRUCTURE OF THE HUMAN ALPHA-THROMBIN COMPLEX WITH A TRIPEPTIDE PHOSPHONATE INHIBITOR. | SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1h9x:A (VAL470) to (VAL505) CYTOCHROME CD1 NITRITE REDUCTASE, REDUCED FORM | ENZYME, NITRITE REDUCTASE, OXIDOREDUCTASE
1h9y:A (VAL470) to (VAL505) CYTOCHROME CD1 NITRITE REDUCTASE, REDUCED FORM COMPLEXED TO CN | ENZYME, NITRITE REDUCTASE, OXIDOREDUCTASE, CN
4zsm:B (MET18) to (GLY41) BACE CRYSTAL STRUCTURE WITH BICYCLIC AMINOTHIAZINE FRAGMENT | ASPARTYL, PROTEASE, BETA-SECRETASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2gum:C (VAL602) to (LEU625) CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF GLYCOPROTEIN B FROM HERPES SIMPLEX VIRUS TYPE I | ENVELOPE GLYCOPROTEIN, MEMBRANE FUSION, VIRAL PROTEIN
2gv6:A (GLN30) to (SER54) CRYSTAL STRUCTURE OF MATRIPTASE WITH INHIBITOR CJ-730 | MATRIPTASE, INHIBITOR, COMPLEX STRUCTURE, HYDROLASE
2gv7:A (GLN30) to (SER54) STRUCTURE OF MATRIPTASE IN COMPLEX WITH INHIBITOR CJ-672 | MATRIPTASE, INHIBITOR, COMPLEX STRUCTURE, HYDROLASE
1tbn:A (LYS101) to (HIS140) NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, MINIMIZED AVERAGE STRUCTURE | CALCIUM-BINDING PROTEIN, PROTEIN KINASE C, PKC, TRANSFERASE
1tbr:K (GLN30) to (THR54) CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN | COMPLEX (SERINE PROTEASE-INHIBITOR), KAZAL-TYPE INHIBITOR, THROMBIN, COMPLEX (SERINE PROTEASE-INHIBITOR) COMPLEX
2w5p:B (ALA92) to (TYR115) DRAE ADHESIN IN COMPLEX WITH CHLORAMPHENICOL SUCCINATE ( MONOCLINIC FORM) | UPEC, DRAE, DAEC, ADHESIN, FIMBRIUM, HAEMAGGLUTININ, CELL PROJECTION, FIMBRIAL ADHESIN, CHLORAMPHENICOL SUCCINATE, CELL ADHESION
3ila:E (THR149) to (PRO204) CRYSTAL STRUCTURE OF RABBIT RYANODINE RECEPTOR 1 N-TERMINAL DOMAIN (9- 205) | BETA TREFOIL, CALCIUM CHANNEL, CALCIUM TRANSPORT, GLYCOPROTEIN, ION TRANSPORT, IONIC CHANNEL, MEMBRANE, PHOSPHOPROTEIN, RECEPTOR, S- NITROSYLATION, TRANSMEMBRANE, TRANSPORT, SIGNALING PROTEIN
4ldu:A (PHE329) to (ASP371) CRYSTAL STRUCTURE OF THE DNA BINDING DOMAIN OF ARABIDOPSIS THALIANA AUXIN RESPONSE FACTOR 5 | TRANSCRIPTION FACTOR, DNA BINDING PROTEIN, NUCLEUS
1te0:B (VAL59) to (THR93) STRUCTURAL ANALYSIS OF DEGS, A STRESS SENSOR OF THE BACTERIAL PERIPLASM | TWO DOMAINS, SERINE PROTEASE, PDZ, ALPHA-BETA PROTEIN, HYDROLASE
1hbn:C (ARG174) to (GLY202) METHYL-COENZYME M REDUCTASE | METHANOGENESIS, BIOLOGICAL METHANOGENESIS, NI-ENZYME, OXIDOREDUCTASE
1hbo:C (ARG174) to (GLY202) METHYL-COENZYME M REDUCTASE MCR-RED1-SILENT | METHANOGENESIS, BIOLOGICAL METHANOGENESIS, NI-ENZYME, OXIDOREDUCTASE
3ina:A (THR180) to (GLU222) CRYSTAL STRUCTURE OF HEPARIN LYASE I H151A MUTANT COMPLEXED WITH A DODECASACCHARIDE HEPARIN | JELLY ROLL, LYASE
1hbv:B (ARG8) to (GLU34) A CHECK ON RATIONAL DRUG DESIGN. CRYSTAL STRUCTURE OF A COMPLEX OF HIV-1 PROTEASE WITH A NOVEL GAMMA-TURN MIMETIC | HYDROLASE (ACID PROTEASE)
1hcg:A (GLN30) to (THR54) STRUCTURE OF HUMAN DES(1-45) FACTOR XA AT 2.2 ANGSTROMS RESOLUTION | COAGULATION FACTOR
1hcu:D (LEU280) to (HIS307) ALPHA-1,2-MANNOSIDASE FROM TRICHODERMA REESEI | GLYCOSYLATION, GLYCOSYL HYDROLASE
4ztq:A (ASP132) to (PHE165) HUMAN AURORA A CATALYTIC DOMAIN BOUND TO FK932 | AURORA, KINASE, INHIBITOR, TRANSFERASE
3io5:A (PHE281) to (GLU305) CRYSTAL STRUCTURE OF A DIMERIC FORM OF THE UVSX RECOMBINASE CORE DOMAIN FROM ENTEROBACTERIA PHAGE T4 | STORAGE DIMER, INACTIVE CONFORMATION, RECA LIKE CORE DOMAIN, ATP- BINDING, DNA DAMAGE, DNA RECOMBINATION, DNA REPAIR, DNA REPLICATION, NUCLEOTIDE-BINDING, DNA BINDING PROTEIN
3io5:B (PHE281) to (GLU306) CRYSTAL STRUCTURE OF A DIMERIC FORM OF THE UVSX RECOMBINASE CORE DOMAIN FROM ENTEROBACTERIA PHAGE T4 | STORAGE DIMER, INACTIVE CONFORMATION, RECA LIKE CORE DOMAIN, ATP- BINDING, DNA DAMAGE, DNA RECOMBINATION, DNA REPAIR, DNA REPLICATION, NUCLEOTIDE-BINDING, DNA BINDING PROTEIN
1tft:A (GLY288) to (ASP309) NMR STRUCTURE OF AN ANTAGONISTS OF THE XIAP-CASPASE-9 INTERACTION COMPLEXED TO THE BIR3 DOMAIN OF XIAP | COMPLEX, LIGAND-PROTEIN, APOPTOSIS, BIR, XIAP
1tfx:A (GLN30) to (SER54) COMPLEX OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR WITH PORCINE TRYPSIN | COMPLEX (SERINE PROTEASE/INHIBITOR), HYDROLASE, INHIBITOR, BLOOD COAGULATION
1hf2:C (ALA130) to (GLY146) CRYSTAL STRUCTURE OF THE BACTERIAL CELL-DIVISION INHIBITOR MINC FROM T. MARITIMA | CELL DIVISION PROTEIN, FTSZ, SEPTUM, BACTERIAL CELL DIVISION, BETA HELIX
1hf2:D (ALA130) to (GLY146) CRYSTAL STRUCTURE OF THE BACTERIAL CELL-DIVISION INHIBITOR MINC FROM T. MARITIMA | CELL DIVISION PROTEIN, FTSZ, SEPTUM, BACTERIAL CELL DIVISION, BETA HELIX
2w7s:C (VAL18) to (VAL35) SPLA SERINE PROTEASE OF STAPHYLOCOCCUS AUREUS (1.8A) | HYDROLASE, FAMILY S1
2w7s:D (VAL18) to (VAL35) SPLA SERINE PROTEASE OF STAPHYLOCOCCUS AUREUS (1.8A) | HYDROLASE, FAMILY S1
2w7u:D (VAL18) to (VAL35) SPLA SERINE PROTEASE OF STAPHYLOCOCCUS AUREUS (2.4A) | HYDROLASE, FAMILY S1
1thp:B (GLN30) to (THR54) STRUCTURE OF HUMAN ALPHA-THROMBIN Y225P MUTANT BOUND TO D-PHE-PRO-ARG- CHLOROMETHYLKETONE | SERINE PROTEASE, FPRCK, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1tie:A (PRO114) to (GLY143) CRYSTAL STRUCTURE OF A KUNITZ-TYPE TRYPSIN INHIBITOR FROM ERYTHRINA CAFFRA SEEDS | PROTEINASE INHIBITOR (TRYPSIN)
1tio:A (GLN30) to (SER54) HIGH PACKING DENSITY FORM OF BOVINE BETA-TRYPSIN IN CYCLOHEXANE | SERINE PROTEASE, BENZAMIDINE INHIBITED, HYDROLASE
4zv0:A (GLU385) to (PRO426) STRUCTURE OF TSE6 IN COMPLEX WITH TSI6 | T6SS EFFECTOR-IMMUNITY PAIR, PROTEIN BINDING
2h3l:B (PHE1334) to (GLN1377) CRYSTAL STRUCTURE OF ERBIN PDZ | PDZ DOMAIN, CELL ADHESION
1hih:B (VAL11) to (GLU34) COMPARATIVE ANALYSIS OF THE X-RAY STRUCTURES OF HIV-1 AND HIV-2 PROTEASES IN COMPLEX WITH CGP 53820, A NOVEL PSEUDOSYMMETRIC INHIBITOR | ASPARTATE PROTEASE, INHIBITED, HIV, HYDROLASE (ASPARTIC PROTEINASE)
1hj4:B (VAL470) to (VAL505) CYTOCHROME CD1 NITRITE REDUCTASE, X-RAY REDUCED DIOXYGEN COMPLEX | ENZYME, NITRITE REDUCTASE, OXIDOREDUCTASE
2h4y:A (SER236) to (LEU258) CRYSTAL STRUCTURE OF HUMAN CASPASE-1 (ARG286->LYS) IN COMPLEX WITH 3- [2-(2-BENZYLOXYCARBONYLAMINO-3-METHYL-BUTYRYLAMINO)-PROPIONYLAMINO]- 4-OXO-PENTANOIC ACID (Z-VAD-FMK) | ALLOSTERIC SITE, DIMER INTERFACE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2h5c:A (ILE31) to (ALA55) 0.82A RESOLUTION CRYSTAL STRUCTURE OF ALPHA-LYTIC PROTEASE AT PH 5 | A-LYTIC PROTEASE, SERINE PROTEASE, ACYLATION TRANSITION STATE, CATALYSIS, PROTEIN FOLDING, PROTEIN STABILITY, PACKING DISTORTION, HYDROLASE
2h5d:A (ILE31) to (ALA55) 0.9A RESOLUTION CRYSTAL STRUCTURE OF ALPHA-LYTIC PROTEASE COMPLEXED WITH A TRANSITION STATE ANALOGUE, MEOSUC-ALA-ALA-PRO-VAL BORONIC ACID | A-LYTIC PROTEASE, SERINE PROTEASE, ACYLATION TRANSITION STATE, CATALYSIS, PROTEIN FOLDING, PROTEIN STABILITY, PACKING DISTORTION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1hk8:A (PRO284) to (ASN318) STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES: NRDD IN COMPLEX WITH DGTP | OXIDOREDUCTASE, REDUCTASE, ALLOSTERIC REGULATION, SUBSTRATE SPECIFICITY
3isy:A (GLU5) to (SER38) CRYSTAL STRUCTURE OF AN INTRACELLULAR PROTEINASE INHIBITOR (IPI, BSU11130) FROM BACILLUS SUBTILIS AT 2.61 A RESOLUTION | INTRACELLULAR PROTEINASE INHIBITOR BSUPI, BETA SANDWICH, GREEK KEY, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, PROTEIN BINDING
1hkx:C (ILE432) to (SER470) CRYSTAL STRUCTURE OF CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE | TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, CALMODULIN- BINDING, PHOSPHORYLATION, ATP-BINDING, ALTERNATIVE SPLICING
1hkx:F (ILE432) to (SER470) CRYSTAL STRUCTURE OF CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE | TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, CALMODULIN- BINDING, PHOSPHORYLATION, ATP-BINDING, ALTERNATIVE SPLICING
2h7c:A (PRO1023) to (GLY1052) CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH COENZYME A | ENZYME, ESTERASE, CHOLESTERYL ESTERASE, HYDROLASE
2h7c:B (PRO2023) to (GLY2052) CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH COENZYME A | ENZYME, ESTERASE, CHOLESTERYL ESTERASE, HYDROLASE
2h7c:D (PRO4023) to (GLY4052) CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH COENZYME A | ENZYME, ESTERASE, CHOLESTERYL ESTERASE, HYDROLASE
2h7c:E (PRO5023) to (GLY5052) CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH COENZYME A | ENZYME, ESTERASE, CHOLESTERYL ESTERASE, HYDROLASE
2h7c:F (PRO6023) to (GLY6052) CRYSTAL STRUCTURE OF HUMAN CARBOXYLESTERASE IN COMPLEX WITH COENZYME A | ENZYME, ESTERASE, CHOLESTERYL ESTERASE, HYDROLASE
1tng:A (GLN30) to (SER54) PREDICTION OF NOVEL SERINE PROTEASE INHIBITORS | HYDROLASE/HYDROLASE INHIBITOR COMPLEX, SERINE PROTEINASE, TRYPSIN, INHIBITOR - AMINOMETHYLCYCLOHEXANE
1tnh:A (GLN30) to (SER54) PREDICTION OF NOVEL SERINE PROTEASE INHIBITORS | HYDROLASE/HYDROLASE INHIBITOR COMPLEX, SERINE PROTEINASE, TRYPSIN, INHIBITOR - FLUOROBENZYLAMINE
1tnk:A (GLN30) to (SER54) PREDICTION OF NOVEL SERINE PROTEASE INHIBITORS | HYDROLASE/HYDROLASE INHIBITOR COMPLEX, SERINE PROTEINASE, TRYPSIN, INHIBITOR - PHENYLPROPYLAMINE
1tnl:A (GLN30) to (SER54) PREDICTION OF NOVEL SERINE PROTEASE INHIBITORS | HYDROLASE/HYDROLASE INHIBITOR COMPLEX, SERINE PROTEINASE, TRYPSIN, INHIBITOR - TRANYLCYPROMINE
3iti:A (GLN15) to (SER37) STRUCTURE OF BOVINE TRYPSIN WITH THE MAD TRIANGLE B3C | PHASING TOOL, 5-AMINO-2,4,6-TRIBROMOISOPHTHALIC ACID, B3C, MAD TRIANGLE, I3C, MAGIC TRIANGLE, DIGESTION, DISULFIDE BOND, HYDROLASE, METAL-BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN
2wbk:A (PRO678) to (GLN704) STRUCTURE OF THE MICHAELIS COMPLEX OF BETA-MANNOSIDASE, MAN2A, PROVIDES INSIGHT INTO THE CONFORMATIONAL ITINERARY OF MANNOSIDE HYDROLYSIS | GLYCOSIDE HYDROLASE, CONFORMATIONAL ITINERARY, HYDROLASE, MANNOSIDASE, BETA-MANNOSIDE, MICHAELIS COMPLEX
2h9e:H (GLN30) to (THR54) CRYSTAL STRUCTURE OF FXA/SELECTIDE/NAPC2 TERNARY COMPLEX | FACTOR XA, NAPC2, SELECTIDE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, BLOOD CLOTTING
2h9v:A (GLY209) to (ASP248) STRUCTURAL BASIS FOR INDUCED-FIT BINDING OF RHO-KINASE TO THE INHIBITOR Y27632 | PROTEIN KINASE-INHIBITOR COMPLEX, TRANSFERASE
1tom:H (GLN30) to (THR54) ALPHA-THROMBIN COMPLEXED WITH HIRUGEN | HYDROLASE, SERINE PROTEASE, KRINGLE, DISEASE MUTATION, COMPLEX (HYDROLASE-INHIBITOR), HYDROLASE-HYDROLASE INHIBITOR COMPLEX, BLOOD COAGULATION-HYDROLASE INHIBITOR COMPLEX
3vlm:A (TYR329) to (LEU369) CRYSTAL STRUCTURE ANALYSIS OF THE MET244ALA VARIANT OF KATG FROM HALOARCULA MARISMORTUI | CATALASE-PEROXIDASE, OXIDOREDUCTASE
3vn3:A (SER48) to (ALA70) FUNGAL ANTIFREEZE PROTEIN EXERTS HYPERACTIVITY BY CONSTRUCTING AN INEQUABLE BETA-HELIX | RIGHT-HANDED BETA-HELIX, ANTIFREEZE PROTEIN
3vn3:B (SER48) to (ALA70) FUNGAL ANTIFREEZE PROTEIN EXERTS HYPERACTIVITY BY CONSTRUCTING AN INEQUABLE BETA-HELIX | RIGHT-HANDED BETA-HELIX, ANTIFREEZE PROTEIN
3iva:A (GLY1162) to (SER1183) STRUCTURE OF THE B12-DEPENDENT METHIONINE SYNTHASE (METH) C-TEMINAL HALF WITH ADOHCY BOUND | METH, TRANSFERASE, REACTIVATION CONFORMATION, H759, COBALAMIN, INTERMODULAR INTERACTIONS, AMINO-ACID BIOSYNTHESIS, COBALT, METAL- BINDING, METHIONINE BIOSYNTHESIS, METHYLTRANSFERASE, S-ADENOSYL-L- METHIONINE, S-ADENOSYL-HOMOCYSTEINE
1ho3:B (VAL146) to (ASN184) CRYSTAL STRUCTURE ANALYSIS OF E. COLI L-ASPARAGINASE II (Y25F MUTANT) | ASPARAGINASE, LEUKEMIA, HYDROLASE
1hos:B (PRO9) to (GLU34) INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE BY A C2- SYMMETRIC PHOSPHINATE SYNTHESIS AND CRYSTALLOGRAPHIC ANALYSIS | HYDROLASE(ACID PROTEINASE)
3iwm:A (VAL18) to (PRO39) THE OCTAMERIC SARS-COV MAIN PROTEASE | SARS-COV, MAIN PROTEASE, OCTAMER, ACTIVE CONFORMATION, HYDROLASE
3iwm:C (VAL18) to (PRO39) THE OCTAMERIC SARS-COV MAIN PROTEASE | SARS-COV, MAIN PROTEASE, OCTAMER, ACTIVE CONFORMATION, HYDROLASE
3iwm:D (MET17) to (PRO39) THE OCTAMERIC SARS-COV MAIN PROTEASE | SARS-COV, MAIN PROTEASE, OCTAMER, ACTIVE CONFORMATION, HYDROLASE
4lla:B (THR106) to (LYS140) CRYSTAL STRUCTURE OF D3D4 DOMAIN OF THE LILRB2 MOLECULE | IG-LIKE DOMAIN, IMMUNE-MODULATORY MOLECULE, IMMUNE SYSTEM
4zzm:A (PRO11) to (TYR30) HUMAN ERK2 IN COMPLEX WITH AN IRREVERSIBLE INHIBITOR | TRANSFERASE
5a0a:E (MET30) to (SER54) CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL ELASTASE IN COMPLEX WITH A DIHYDROPYRIMIDONE INHIBITOR | TRYPSIN FAMILY FOLD, PROTEASE, HYDROLASE, HYDROLASE- INHIBITOR COMPLEX
5a0d:A (LYS102) to (VAL135) N-TERMINAL THIOESTER DOMAIN OF SURFACE PROTEIN FROM CLOSTRIDIUM PERFRINGENS, CYS138ALA MUTANT | CELL ADHESION, SURFACE-ASSOCIATED PROTEIN, GRAM-POSITIVE, ADHESIN, INTERNAL THIOESTER, THIOESTER DOMAIN
2whh:A (PRO9) to (GLU34) HIV-1 PROTEASE TETHERED DIMER Q-PRODUCT COMPLEX ALONG WITH NUCLEOPHILIC WATER MOLECULE | PROTEASE, HYDROLASE, DRUG DESIGN, TRANSFERASE, NUCLEOTIDYLTRANSFERASE, RNA-DIRECTED DNA POLYMERASE, CATALYTIC MECHANISM, MULTIFUNCTIONAL ENZYME, TRANSITION STATE, ASPARTYL PROTEASE
2whh:A (PRO1009) to (GLU1034) HIV-1 PROTEASE TETHERED DIMER Q-PRODUCT COMPLEX ALONG WITH NUCLEOPHILIC WATER MOLECULE | PROTEASE, HYDROLASE, DRUG DESIGN, TRANSFERASE, NUCLEOTIDYLTRANSFERASE, RNA-DIRECTED DNA POLYMERASE, CATALYTIC MECHANISM, MULTIFUNCTIONAL ENZYME, TRANSITION STATE, ASPARTYL PROTEASE
2whx:A (GLU93) to (LEU128) A SECOND CONFORMATION OF THE NS3 PROTEASE-HELICASE FROM DENGUE VIRUS | TRANSCRIPTION, HYDROLASE, ATP-BINDING, RETICULUM, NUCLEOTIDYLTRANSFERASE, MULTIFUNCTIONAL ENZYME, TRANSCRIPTION REGULATION, RIBONUCLEOPROTEIN, RNA-DIRECTED RNA POLYMERASE, RNA REPLICATION, ENVELOPE PROTEIN,
4lmh:B (LYS398) to (GLY446) CRYSTAL STRUCTURE OF THE OUTER MEMBRANE DECAHEME CYTOCHROME OMCA | GREEK KEY BETA BARREL, ELECTRON TRANSPORT C-TYPE CYTOCHROME, OUTER MEMBRANE, ELECTRON TRANSPORT
4lmh:C (LYS398) to (GLY446) CRYSTAL STRUCTURE OF THE OUTER MEMBRANE DECAHEME CYTOCHROME OMCA | GREEK KEY BETA BARREL, ELECTRON TRANSPORT C-TYPE CYTOCHROME, OUTER MEMBRANE, ELECTRON TRANSPORT
2wii:C (PHE75) to (GLY104) COMPLEMENT C3B IN COMPLEX WITH FACTOR H DOMAINS 1-4 | IMMUNE SYSTEM, SUSHI, SECRETED, POLYMORPHISM, GLYCOPROTEIN, COMPLEMENT SYSTEM, COMPLEMENT PATHWAY, IMMUNE RESPONSE, INNATE IMMUNITY, DISEASE MUTATION, INFLAMMATORY RESPONSE, COMPLEMENT ALTERNATE PATHWAY, CLEAVAGE ON PAIR OF BASIC RESIDUES, AGE-RELATED MACULAR DEGENERATION, REGULATOR OF COMPLEMENT ACTIVATION, ALTERNATIVE PATHWAY, ALTERNATIVE SPLICING, PHOSPHOPROTEIN, DISULFIDE BOND, THIOESTER BOND
4lnb:B (ARG370) to (GLY388) ASPERGILLUS FUMIGATUS PROTEIN FARNESYLTRANSFERASE TERNARY COMPLEX WITH FARNESYLDIPHOSPHATE AND ETHYLENEDIAMINE SCAFFOLD INHIBITOR 5 | ISOPRENOID AND CAAX-CONTAINING PROTEIN SUBSTRATE, FARNESYLATION, TRANSFERASE
3vsm:A (ASN680) to (GLU702) THE CRYSTAL STRUCTURE OF NOVEL CHONDROITION LYASE ODV-E66, BACULOVIRUS ENVELOPE PROTEIN | ALPHA/ALPHA TROID, BETA-SANDWICH, LYASE ACTIVATOR
5a1h:A (ARG53) to (ASP88) CRYSTAL STRUCTURE OF HUMAN SPINDLIN3 | CELL CYCLE
5a1h:B (ARG53) to (ASP88) CRYSTAL STRUCTURE OF HUMAN SPINDLIN3 | CELL CYCLE
5a1h:C (ARG53) to (ASP88) CRYSTAL STRUCTURE OF HUMAN SPINDLIN3 | CELL CYCLE
5a1h:C (ARG148) to (TYR175) CRYSTAL STRUCTURE OF HUMAN SPINDLIN3 | CELL CYCLE
1hvi:A (VAL11) to (GLU34) INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEASE)
1hvj:B (VAL11) to (GLU34) INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEASE)
1hvk:B (VAL11) to (GLU34) INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEASE)
3vsn:A (ASN680) to (GLU702) THE CRYSTAL STRUCTURE OF NOVEL CHONDROITION LYASE ODV-E66, BACULOVIRUS ENVELOPE PROTEIN | ALPHA/ALPHA TROID, BETA-SANDWICH, LYASE ACTIVATOR
4lnv:B (PHE224) to (GLY257) CRYSTAL STRUCTURE OF TEP1S | IMMUNE SYSTEM, INNATE IMMUNITY, LRIM1 AND APL1C
4lo7:A (ASN594) to (ASN626) HA70(D3)-HA17-HA33 | PROGENITOR TOXIN COMPLEX, BOTULINUM NEUROTOXIN, BOTULISM, NEUROTOXIN ASSOCIATED PROTEIN, HEMAGGLUTININ, CARBOHYDRATE/SUGAR BINDING, SECRETED PROTEIN, PROTEIN TRANSPORT
4lo7:E (ASN594) to (ASN626) HA70(D3)-HA17-HA33 | PROGENITOR TOXIN COMPLEX, BOTULINUM NEUROTOXIN, BOTULISM, NEUROTOXIN ASSOCIATED PROTEIN, HEMAGGLUTININ, CARBOHYDRATE/SUGAR BINDING, SECRETED PROTEIN, PROTEIN TRANSPORT
4lo8:A (ASN594) to (ASN626) HA70(D3)-HA17 | PROGENITOR TOXIN COMPLEX, BOTULINUM NEUROTOXIN, BOTULISM, NEUROTOXIN ASSOCIATED PROTEIN, HEMAGGLUTININ, CARBOHYDRATE/SUGAR BINDING, SECRETED PROTEIN, PROTEIN TRANSPORT
1hxw:B (VAL11) to (GLU34) HIV-1 PROTEASE DIMER COMPLEXED WITH A-84538 | ASPARTYL PROTEASE, HYDROLASE, ASPARTIC PROTEINASE, HIV, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4lpc:A (THR696) to (GLU728) CRYSTAL STRUCTURE OF E.COLI BRANCHING ENZYME IN COMPLEX WITH MALTOHEPTAOSE | BRANCHING ENZYME, MALTOHEPTAOSE, LINEAR POLYSACCHARIDE, STARCH BIOSYNTHETIC PATHWAY, TRANSFERASE
4lpc:B (THR696) to (GLU728) CRYSTAL STRUCTURE OF E.COLI BRANCHING ENZYME IN COMPLEX WITH MALTOHEPTAOSE | BRANCHING ENZYME, MALTOHEPTAOSE, LINEAR POLYSACCHARIDE, STARCH BIOSYNTHETIC PATHWAY, TRANSFERASE
4lpc:D (GLY695) to (GLU728) CRYSTAL STRUCTURE OF E.COLI BRANCHING ENZYME IN COMPLEX WITH MALTOHEPTAOSE | BRANCHING ENZYME, MALTOHEPTAOSE, LINEAR POLYSACCHARIDE, STARCH BIOSYNTHETIC PATHWAY, TRANSFERASE
4lq1:B (THR696) to (GLU728) CRYSTAL STRUCTURE OF E.COLI BRANCHING ENZYME IN COMPLEX WITH MALTOHEXAOSE | BRANCHING ENZYME, MALTOHEXAOSE, LINEAR POLYSACCHARIDE, STARCH BIOSYNTHETIC PATHWAY, ALPHA/BETA BARREL, TRANSFERASE
1tzo:A (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1tzo:B (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1tzo:C (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1tzo:D (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1tzo:E (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1tzo:F (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1tzo:G (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1tzo:H (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1tzo:I (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1tzo:J (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1tzo:K (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1tzo:L (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1tzo:M (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1tzo:O (ASN268) to (SER337) CRYSTAL STRUCTURE OF THE ANTHRAX TOXIN PROTECTIVE ANTIGEN HEPTAMERIC PREPORE | HEPTAMER, TOXIN
1i1e:A (GLU1202) to (GLY1235) CRYSTAL STRUCTURE OF CLOSTRIDIUM BOTULINUM NEUROTOXIN B COMPLEXED WITH DOXORUBICIN | BOTULINUM, NEUROTOXIN, METALLOPROTEASE, COMPLEX, DOXORUBICIN, HYDROLASE
2wms:A (ASP8) to (ILE39) CRYSTAL STRUCTURE OF CHECKPOINT KINASE 1 (CHK1) IN COMPLEX WITH INHIBITORS | SERINE/THREONINE-PROTEIN KINASE, POLYMORPHISM, PHOSPHOPROTEIN, UBL CONJUGATION, ISOPEPTIDE BOND, CHECKPOINT KINASE, NUCLEOTIDE-BINDING, SERINE/THREONINE KINASE, DNA DAMAGE, DNA REPAIR, ATP-BINDING, TRANSFERASE, CHK1, KINASE, NUCLEUS, CYTOPLASM, CELL CYCLE
5a21:G (PRO94) to (ASN132) STRUCTURE OF BACTERIOPHAGE SPP1 HEAD-TO-TAIL INTERFACE WITHOUT DNA AND TAPE MEASURE PROTEIN | VIRAL PROTEIN, VIRAL INFECTION, TAILED BACTERIOPHAGE, SIPHOVIRIDAE, SPP1, VIRAL ASSEMBLY, HEAD-TO-TAIL INTERFACE, DNA GATEKEEPER, ALLOSTERIC MECHANISM, CONCERTED REORGANISATION, DIAPHRAGM GATING
2hrq:A (PRO1023) to (GLY1052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 (HCE1) IN COVALENT COMPLEX WITH THE NERVE AGENT SOMAN (GD) | HYDROLASE, CARBOXYLESTERASE, SOMAN
2hrq:B (PRO2023) to (GLY2052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 (HCE1) IN COVALENT COMPLEX WITH THE NERVE AGENT SOMAN (GD) | HYDROLASE, CARBOXYLESTERASE, SOMAN
2hrq:C (PRO3023) to (GLY3052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 (HCE1) IN COVALENT COMPLEX WITH THE NERVE AGENT SOMAN (GD) | HYDROLASE, CARBOXYLESTERASE, SOMAN
2hrq:D (PRO4023) to (GLY4052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 (HCE1) IN COVALENT COMPLEX WITH THE NERVE AGENT SOMAN (GD) | HYDROLASE, CARBOXYLESTERASE, SOMAN
2hrq:E (PRO5023) to (GLY5052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 (HCE1) IN COVALENT COMPLEX WITH THE NERVE AGENT SOMAN (GD) | HYDROLASE, CARBOXYLESTERASE, SOMAN
2hs1:A (VAL11) to (GLU34) ULTRA-HIGH RESOLUTION X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE V32I MUTANT WITH TMC114 (DARUNAVIR) INHIBITOR | ULTRA-HIGH RESOLUTION ACTIVE SITE SURFACE BINDING SITE, HYDROLASE
4lub:B (LYS76) to (HIS189) X-RAY STRUCTURE OF PREPHENATE DEHYDRATASE FROM STREPTOCOCCUS MUTANS | DEHYDRATASE, DEHYDRATION, LYASE
1u5u:A (LEU190) to (LYS222) THE STRUCTURE OF AN ALLENE OXIDE SYNTHASE REVEALS A NOVEL USE FOR A CATALASE FOLD | ALLENE OXIDE SYNTHASE, CATALASE, HEME, EICOSANOID, FUSION PROTEIN, LYASE
1u5z:A (LEU155) to (PHE185) THE CRYSTAL STRUCTURE OF MURINE APRIL, PH 8.5 | TNFSF, CYTOKINE, TRIMER, JELLY-ROLL, HORMONE-GROWTH FACTOR COMPLEX
1i5p:A (GLY593) to (PRO626) INSECTICIDAL CRYSTAL PROTEIN CRY2AA | HELICAL BUNDLE, BETA PRISM, LECTIN-LIKE BETA SANDWICH, JELLY ROLL, TOXIN
1i84:S (ALA46) to (SER71) CRYO-EM STRUCTURE OF THE HEAVY MEROMYOSIN SUBFRAGMENT OF CHICKEN GIZZARD SMOOTH MUSCLE MYOSIN WITH REGULATORY LIGHT CHAIN IN THE DEPHOSPHORYLATED STATE. ONLY C ALPHAS PROVIDED FOR REGULATORY LIGHT CHAIN. ONLY BACKBONE ATOMS PROVIDED FOR S2 FRAGMENT. | MUSCLE PROTEIN, SMOOTH MUSCLE, MYOSIN SUBFRAGMENT 2, HEAVY MEROMYOSIN, ESSENTIAL LIGHT CHAIN, REGULATORY LIGHT CHAIN, MOTOR PROTEIN, COILED-COIL, CONTRACTILE PROTEIN
1i84:V (ALA46) to (SER71) CRYO-EM STRUCTURE OF THE HEAVY MEROMYOSIN SUBFRAGMENT OF CHICKEN GIZZARD SMOOTH MUSCLE MYOSIN WITH REGULATORY LIGHT CHAIN IN THE DEPHOSPHORYLATED STATE. ONLY C ALPHAS PROVIDED FOR REGULATORY LIGHT CHAIN. ONLY BACKBONE ATOMS PROVIDED FOR S2 FRAGMENT. | MUSCLE PROTEIN, SMOOTH MUSCLE, MYOSIN SUBFRAGMENT 2, HEAVY MEROMYOSIN, ESSENTIAL LIGHT CHAIN, REGULATORY LIGHT CHAIN, MOTOR PROTEIN, COILED-COIL, CONTRACTILE PROTEIN
2hyx:A (TRP611) to (ASN630) STRUCTURE OF THE C-TERMINAL DOMAIN OF DIPZ FROM MYCOBACTERIUM TUBERCULOSIS | THIOREDOXIN FOLD, JELLY-ROLL, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, UNKNOWN FUNCTION
2hyx:B (TRP611) to (ASN630) STRUCTURE OF THE C-TERMINAL DOMAIN OF DIPZ FROM MYCOBACTERIUM TUBERCULOSIS | THIOREDOXIN FOLD, JELLY-ROLL, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, UNKNOWN FUNCTION
2hyx:D (TRP611) to (ASN630) STRUCTURE OF THE C-TERMINAL DOMAIN OF DIPZ FROM MYCOBACTERIUM TUBERCULOSIS | THIOREDOXIN FOLD, JELLY-ROLL, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, UNKNOWN FUNCTION
2hyy:C (ASP241) to (GLU275) HUMAN ABL KINASE DOMAIN IN COMPLEX WITH IMATINIB (STI571, GLIVEC) | TYROSINE KINASE, TRANSFERASE
2hz0:B (ASP241) to (LEU273) ABL KINASE DOMAIN IN COMPLEX WITH NVP-AEG082 | TYROSINE KINASE, TRANSFERASE
2hzi:A (GLY383) to (ILE418) ABL KINASE DOMAIN IN COMPLEX WITH PD180970 | TYROSINE KINASE, TRANSFERASE
4m0l:A (ARG384) to (ILE415) GAMMA SUBUNIT OF THE TRANSLATION INITIATION FACTOR 2 FROM SULFOLOBUS SOLFATARICUS COMPLEXED WITH GDP | AIF2, AIF2 GAMMA SUBUNIT, G-PROTEIN, TRANSLATION, TRANSLATION INITIATION, PROTEIN BIOSYNTHESIS, RNA-BINDING, GTP-BINDING, NUCLEOTIDE-BINDING
2i0a:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF KB-19 COMPLEXED WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2i0d:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF AD-81 COMPLEXED WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
1uf2:P (GLN182) to (VAL210) THE ATOMIC STRUCTURE OF RICE DWARF VIRUS (RDV) | VIRUS COMPONENTS, ICOSAHEDRAL VIRUS
1uf2:D (GLN182) to (VAL210) THE ATOMIC STRUCTURE OF RICE DWARF VIRUS (RDV) | VIRUS COMPONENTS, ICOSAHEDRAL VIRUS
1uf2:F (GLN182) to (VAL210) THE ATOMIC STRUCTURE OF RICE DWARF VIRUS (RDV) | VIRUS COMPONENTS, ICOSAHEDRAL VIRUS
1uf2:H (GLN182) to (VAL210) THE ATOMIC STRUCTURE OF RICE DWARF VIRUS (RDV) | VIRUS COMPONENTS, ICOSAHEDRAL VIRUS
1uf2:S (GLN182) to (VAL210) THE ATOMIC STRUCTURE OF RICE DWARF VIRUS (RDV) | VIRUS COMPONENTS, ICOSAHEDRAL VIRUS
1uf2:I (GLN182) to (VAL210) THE ATOMIC STRUCTURE OF RICE DWARF VIRUS (RDV) | VIRUS COMPONENTS, ICOSAHEDRAL VIRUS
2i32:B (LYS3) to (GLU36) STRUCTURE OF A HUMAN ASF1A-HIRA COMPLEX AND INSIGHTS INTO SPECIFICITY OF HISTONE CHAPERONE COMPLEX ASSEMBLY | HISTONE DEPOSITION, CHROMATIN REGULATION, HISTONE CHAPERONES, ASF1, HIRA, CAF-1, REPLICATION CHAPERONE
1igq:C (LYS306) to (TYR336) C-TERMINAL DOMAIN OF TRANSCRIPTIONAL REPRESSOR PROTEIN KORB | SH3 DOMAIN, DIMERIZATION DOMAIN, TRANSCRIPTION
1igq:D (LYS306) to (TYR336) C-TERMINAL DOMAIN OF TRANSCRIPTIONAL REPRESSOR PROTEIN KORB | SH3 DOMAIN, DIMERIZATION DOMAIN, TRANSCRIPTION
1igu:A (LYS306) to (ASP338) C-TERMINAL DOMAIN OF THE TRANSCRIPTIONAL REPRESSOR PROTEIN KORB | SH3 DOMAIN, DIMERIZATION DOMAIN, TRANSCRIPTION
3w6m:A (GLY38) to (GLY70) CONTRIBUTION OF DISULFIDE BOND TOWARD THERMOSTABILITY IN HYPERTHERMOSTABLE ENDOCELLULASE | HYPERTHERMOPHILIC, DISULFIDE BOND, TIM BARREL, GLYCOSYL HYDROLASE, HYDROLIZAITON, MEMBRANE-BOUND, HYDROLASE
3w6w:A (THR558) to (ALA603) CRYSTAL STRUCTURE OF MELB HOLO-PROTYROSINASE FROM ASPERUGILLUS ORYZAE | FOUR HELIX BUNDLE, METAL BINDING PROTEIN, OXIDOREDUCTASE
3j08:A (SER268) to (ARG304) HIGH RESOLUTION HELICAL RECONSTRUCTION OF THE BACTERIAL P-TYPE ATPASE COPPER TRANSPORTER COPA | P-TYPE ATPASE, COPPER TRANSPORTER, COPA, ADENOSINE TRIPHOSPHATASES, ARCHAEAL PROTEINS, CATION TRANSPORT PROTEINS, CRYOELECTRON MICROSCOPY, HYDROLASE, METAL TRANSPORT
3j08:B (SER268) to (ARG304) HIGH RESOLUTION HELICAL RECONSTRUCTION OF THE BACTERIAL P-TYPE ATPASE COPPER TRANSPORTER COPA | P-TYPE ATPASE, COPPER TRANSPORTER, COPA, ADENOSINE TRIPHOSPHATASES, ARCHAEAL PROTEINS, CATION TRANSPORT PROTEINS, CRYOELECTRON MICROSCOPY, HYDROLASE, METAL TRANSPORT
2wvu:B (TYR396) to (LYS421) CRYSTAL STRUCTURE OF A MICHAELIS COMPLEX OF ALPHA-L- FUCOSIDASE GH29 FROM BACTEROIDES THETAIOTAOMICRON WITH THE SYNTHETIC SUBSTRATE 4-NITROPHENYL-ALPHA-L-FUCOSE | ALPHA-L-FUCOSE, HYDROLASE, GLYCOSIDE HYDROLASE FAMILY 29
5a7h:A (PRO23) to (GLY52) COMPARISON OF THE STRUCTURE AND ACTIVITY OF GLYCOSYLATED AND AGLYCOSYLATED HUMAN CARBOXYLESTERASE 1 | HYDROLASE, ESTERASE, AGLYCOSYLATED
4m3q:B (LEU586) to (THR620) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE PROTO-ONCOGENE TYROSINE-PROTEIN KINASE MER IN COMPLEX WITH INHIBITOR UNC1917 | TYROSINE KINASE, ACUTE LYMPHOBLASTIC LEUKEMIA, RATIONAL STRUCTURE- BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3j0k:B (THR1170) to (ILE1194) ORIENTATION OF RNA POLYMERASE II WITHIN THE HUMAN VP16-MEDIATOR-POL II-TFIIF ASSEMBLY | TRANSFERASE-TRANSCRIPTION COMPLEX
3j0k:K (LYS18) to (HIS40) ORIENTATION OF RNA POLYMERASE II WITHIN THE HUMAN VP16-MEDIATOR-POL II-TFIIF ASSEMBLY | TRANSFERASE-TRANSCRIPTION COMPLEX
3w94:A (MET809) to (THR833) STRUCTURE OF ORYZIAS LATIPES ENTEROPEPTIDASE LIGHT CHAIN | SERINE PROTEASE, HYDROLASE
3w94:B (MET809) to (THR833) STRUCTURE OF ORYZIAS LATIPES ENTEROPEPTIDASE LIGHT CHAIN | SERINE PROTEASE, HYDROLASE
1io1:A (LEU220) to (ASP250) CRYSTAL STRUCTURE OF F41 FRAGMENT OF FLAGELLIN | BETA-FOLIUM, FLAGELLIN, STRUCTURAL PROTEIN
1ioe:A (GLN30) to (THR54) HUMAN COAGULATION FACTOR XA IN COMPLEX WITH M55532 | HYDROLASE, SERINE PROTEASE, BLOOD COAGULATION FACTOR, COMPLEX
5a9p:A (ALA108) to (VAL155) CRYSTAL STRUCTURE OF OPEROPHTERA BRUMATA CPV18 POLYHEDRA | VIRAL PROTEIN, INSECT VIRUS OCCLUSION BODY, MICROCRYSTAL
1umh:A (GLY149) to (ASP187) STRUCTURAL BASIS OF SUGAR-RECOGNIZING UBIQUITIN LIGASE | UBIQUITIN, SCF, UBIQUITIN LIGASE, LECTIN, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS
1umr:A (SER66) to (ALA119) CRYSTAL STRUCTURE OF THE PLATELET ACTIVATOR CONVULXIN, A DISULFIDE LINKED A4B4 CYCLIC TETRAMER FROM THE VENOM OF CROTALUS DURISSUS TERRIFICUS | LECTIN, C-TYPE LECTIN, PLATELET, SUGAR-BINDING PROTEIN, ACTIVATOR, SNAKE VENOM
2ic1:A (ARG57) to (SER84) CRYSTAL STRUCTURE OF HUMAN CYSTEINE DIOXYGENASE IN COMPLEX WITH SUBSTRATE CYSTEINE | CUPIN, ENZYME-SUBSTRATE COMPLEX, OXIDOREDUCTASE
2id0:D (LYS89) to (ALA114) ESCHERICHIA COLI RNASE II | RNASE, EXORIBONUCLEASE, RIBONUCLEASE, EXONUCLEASE, NUCLEASE, HYDROLYASE, MRNA DECAY, RNR FAMILY, HYDROLASE
2wyr:A (VAL96) to (GLY135) 3-D STRUCTURE OF PHTET1-12S, DODECAMER IN THE ASYMMETRIC UNIT | HYDROLASE, LARGE SELF-ASSEMBLED DODECAMER, HYPERTHERMOPHILIC
2wyr:B (VAL427) to (GLY466) 3-D STRUCTURE OF PHTET1-12S, DODECAMER IN THE ASYMMETRIC UNIT | HYDROLASE, LARGE SELF-ASSEMBLED DODECAMER, HYPERTHERMOPHILIC
2wyr:C (HIS757) to (ILE796) 3-D STRUCTURE OF PHTET1-12S, DODECAMER IN THE ASYMMETRIC UNIT | HYDROLASE, LARGE SELF-ASSEMBLED DODECAMER, HYPERTHERMOPHILIC
2wyr:D (VAL1089) to (GLY1128) 3-D STRUCTURE OF PHTET1-12S, DODECAMER IN THE ASYMMETRIC UNIT | HYDROLASE, LARGE SELF-ASSEMBLED DODECAMER, HYPERTHERMOPHILIC
2wyr:F (HIS1750) to (GLY1790) 3-D STRUCTURE OF PHTET1-12S, DODECAMER IN THE ASYMMETRIC UNIT | HYDROLASE, LARGE SELF-ASSEMBLED DODECAMER, HYPERTHERMOPHILIC
2wyr:G (HIS2081) to (GLY2121) 3-D STRUCTURE OF PHTET1-12S, DODECAMER IN THE ASYMMETRIC UNIT | HYDROLASE, LARGE SELF-ASSEMBLED DODECAMER, HYPERTHERMOPHILIC
2wyr:H (VAL2413) to (GLY2452) 3-D STRUCTURE OF PHTET1-12S, DODECAMER IN THE ASYMMETRIC UNIT | HYDROLASE, LARGE SELF-ASSEMBLED DODECAMER, HYPERTHERMOPHILIC
2wyr:I (VAL2744) to (GLY2783) 3-D STRUCTURE OF PHTET1-12S, DODECAMER IN THE ASYMMETRIC UNIT | HYDROLASE, LARGE SELF-ASSEMBLED DODECAMER, HYPERTHERMOPHILIC
2wyr:J (VAL3075) to (GLY3114) 3-D STRUCTURE OF PHTET1-12S, DODECAMER IN THE ASYMMETRIC UNIT | HYDROLASE, LARGE SELF-ASSEMBLED DODECAMER, HYPERTHERMOPHILIC
2wyr:K (HIS3405) to (GLY3445) 3-D STRUCTURE OF PHTET1-12S, DODECAMER IN THE ASYMMETRIC UNIT | HYDROLASE, LARGE SELF-ASSEMBLED DODECAMER, HYPERTHERMOPHILIC
2wyr:L (VAL3737) to (GLY3776) 3-D STRUCTURE OF PHTET1-12S, DODECAMER IN THE ASYMMETRIC UNIT | HYDROLASE, LARGE SELF-ASSEMBLED DODECAMER, HYPERTHERMOPHILIC
5ab2:B (PRO548) to (HIS587) CRYSTAL STRUCTURE OF AMINOPEPTIDASE ERAP2 WITH LIGAND | AMINOPEPTIDASE, ERAP2, ZINC ION BINDING, ENDOPLASMIC RETICULUM, HYDROLASE, METALLOPROTEASE, L-RAP, ANTIGEN PRESENTATION
2wzj:D (GLN47) to (LEU74) CATALYTIC AND UBA DOMAIN OF KINASE MARK2/(PAR-1) K82R, T208E DOUBLE MUTANT | UBA DOMAIN, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, SIGNALING PROTEIN, S/T PROTEIN KINASE, DIFFERENTIATION, DEVELOPMENTAL PROTEIN
1ivy:B (ARG396) to (LYS425) PHYSIOLOGICAL DIMER HPP PRECURSOR | CARBOXYPEPTIDASE, SERINE CARBOXYPEPTIDASE, PROTECTIVE PROTEIN, GLYCOPROTEIN, ZYMOGEN
1utk:A (GLN30) to (SER54) TRYPSIN SPECIFICITY AS ELUCIDATED BY LIE CALCULATIONS, X-RAY STRUCTURES AND ASSOCIATION CONSTANT MEASUREMENTS | HYDROLASE, TRYPSIN, INHIBITOR SPECIFICITY, ELECTROSTATIC INTERACTIONS, COLD-ADAPTATION, MOLECULAR DYNAMICS, BINDING FREE ENERGY
1utl:M (GLN30) to (SER54) TRYPSIN SPECIFICITY AS ELUCIDATED BY LIE CALCULATIONS, X-RAY STRUCTURES AND ASSOCIATION CONSTANT MEASUREMENTS | HYDROLASE, TRYPSIN, INHIBITOR SPECIFICITY, ELECTROSTATIC INTERACTIONS, COLD-ADAPTATION, MOLECULAR DYNAMICS, BINDING FREE ENERGY
1utn:A (GLN30) to (SER54) TRYPSIN SPECIFICITY AS ELUCIDATED BY LIE CALCULATIONS, X-RAY STRUCTURES AND ASSOCIATION CONSTANT MEASUREMENTS | HYDROLASE, TRYPSIN, INHIBITOR SPECIFICITY, ELECTROSTATIC INTERACTIONS, COLD-ADAPTATION, MOLECULAR DYNAMICS, BINDING FREE ENERGY HYDROLASE,
3wdt:C (GLY183) to (ALA218) THE APO-FORM STRUCTURE OF PTLIC16A FROM PAECILOMYCES THERMOPHILA | 1,3-1,4-BETA-GLUCANASE, 1,3(4)-BETA-GLUCANASE, PTLIC16A, BETA- JELLYROLL FOLD, HYDROLASE
4mct:B (GLY62) to (ILE85) P. VULGARIS HIGBA STRUCTURE, CRYSTAL FORM 1 | BACTERIAL TOXINS, BIOFILMS, CELL METABOLISM, ENERGY METABOLISM, HELIX-TURN-HELIX TRANSCRIPTION FACTORS, MICROBIAL PATHOGENESIS, STRESS RESPONSE, STRINGENT RESPONSE, TRANSCRIPTION REPRESSOR, TRANSLATION CONTROL, TOXIN
3j2w:B (TYR1001) to (LEU1044) ELECTRON CRYO-MICROSCOPY OF CHIKUNGUNYA VIRUS | E1-E2 GLYCOPROTEIN, NUCLEOCAPSID PROTEIN, TRANSMEMBRANE HELIX, VIRUS
3j2w:C (TYR2001) to (LEU2044) ELECTRON CRYO-MICROSCOPY OF CHIKUNGUNYA VIRUS | E1-E2 GLYCOPROTEIN, NUCLEOCAPSID PROTEIN, TRANSMEMBRANE HELIX, VIRUS
4md8:D (GLN117) to (THR145) CRYSTAL STRUCTURE OF FULL-LENGTH SYMMETRIC CK2 HOLOENZYME WITH MUTATED ALPHA SUBUNIT (F121E) | PROTEIN SERINE/THREONINE KINASE, TRANSFERASE
3wel:A (LYS845) to (GLU907) SUGAR BEET ALPHA-GLUCOSIDASE WITH ACARVIOSYL-MALTOTRIOSE | ALPHA-GLUCOSIDASE, GLYCOSIDE HYDROLASE FAMILY 31, (BETA/ALPHA)8- BARREL, ACARBOSE DERIVATIVE, HYDROLASE
3j31:K (ALA180) to (ARG214) LIFE IN THE EXTREMES: ATOMIC STRUCTURE OF SULFOLOBUS TURRETED ICOSAHEDRAL VIRUS | VIRUS ASSEMBLY, EVOLUTION, ARCHAEA, VIRUS
5adx:K (SER85) to (ASP107) CRYOEM STRUCTURE OF DYNACTIN COMPLEX AT 4.0 ANGSTROM RESOLUTION | STRUCTURAL PROTEIN, DYNEIN CO-FACTOR, ACTIN-LIKE FILAMENT, CELLULAR CARGO TRANSPORT
2ijm:B (ARG421) to (CYS456) CRYSTAL STRUCTURE OF FOCAL ADHESION KINASE DOMAIN WITH 2 MOLECULES IN THE ASYMMETRIC UNIT COMPLEXED WITH ADP AND ATP | KINASE CATALYTIC DOMAIN, SIGNALING PROTEIN,TRANSFERASE
5af9:H (GLN30) to (THR54) THROMBIN IN COMPLEX WITH 4-METHOXY-N-(2-PYRIDINYL)BENZAMIDE | HYDROLASE, HYDROLASE INHIBITOR COMPLEX, SERINE PROTEASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, BLOOD CLOTTING INHIBITOR, THROMBIN INHIBITOR, FRAGMENT, GLYCOSYLATION, BLOOD
5afu:K (SER85) to (ASP107) CRYO-EM STRUCTURE OF DYNEIN TAIL-DYNACTIN-BICD2N COMPLEX | DYNEIN, DYNACTIN, BICD2, MOTOR, TRANSPORT, MOTOR PROTEIN
5afy:H (GLN30) to (THR54) THROMBIN IN COMPLEX WITH 3-CHLORO-BENZAMIDE | HYDROLASE, HYDROLASE INHIBITOR COMPLEX, SERINE PROTEASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, BLOOD CLOTTING INHIBITOR, THROMBIN INHIBITOR, FRAGMENT, GLYCOSYLATION, BLOOD
1uz4:A (PHE24) to (ILE41) COMMON INHIBITION OF BETA-GLUCOSIDASE AND BETA-MANNOSIDASE BY ISOFAGOMINE LACTAM REFLECTS DIFFERENT CONFORMATIONAL INTINERARIES FOR GLUCOSIDE AND MANNOSIDE HYDROLYSIS | MANNOSIDASE, INHIBITOR, ISOFAGOMANINELACTAM, HYDROLASE
2io6:A (GLU298) to (LYS331) WEE1 KINASE COMPLEXED WITH INHIBITOR PD330961 | PROTEIN-INHIBITOR COMPLEX, TRANSFERASE
3wh9:B (PHE2) to (GLY17) THE LIGAND-FREE STRUCTURE OF MANBK FROM ASPERGILLUS NIGER BK01 | BETA-MANNANASE, RATIONAL DESIGN, THERMOPHILIC, TIM-BARREL FOLD, HYDROLASE
2x3a:A (GLY23) to (LEU55) ASAP1 INACTIVE MUTANT E294Q, AN EXTRACELLULAR TOXIC ZINC METALLOENDOPEPTIDASE | HYDROLASE
5ahg:H (GLN30) to (THR54) THROMBIN IN COMPLEX WITH ((4-CHLOROPHENYL)SULFAMOYL)) DIEMETHYLAMINE | HYDROLASE, HYDROLASE INHIBITOR COMPLEX, SERINE PROTEASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, BLOOD CLOTTING INHIBITOR, THROMBIN INHIBITOR, FRAGMENT, GLYCOSYLATION, BLOOD
1j14:A (GLN30) to (SER54) BENZAMIDINE IN COMPLEX WITH RAT TRYPSIN MUTANT X99RT | SERINE PROTEASE, HYDROLASE, SERINE PROTEINASE
3wi0:A (TRP449) to (LYS482) P453H/I471T MUTANT OF PB2 MIDDLE DOMAIN FROM INFLUENZA VIRUS A/PUERTO RICO/8/34(H1N1) | INFLUENZA A VIRUS, PB2, MIDDLE DOMAIN, CAP BINDING, VIRAL PROTEIN
1j17:T (GLN30) to (SER54) FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH RAT TRYPSIN MUTANT X99/175/190RT | SERINE PROTEASE, HYDROLASE, SERINE PROTEINASE
3wi1:A (TRP449) to (LYS482) P453H/I471T MUTANT OF PB2 MIDDLE DOMAIN FROM INFLUENZA VIRUS A/PUERTO RICO/8/34(H1N1) WITH M7GTP | INFLUENZA A VIRUS, PB2, MIDDLE DOMAIN, CAP BINDING, VIRAL PROTEIN
5aj8:B (ASN220) to (ALA238) TUBULIN BINDING COFACTOR C FROM LEISHMANIA MAJOR | STRUCTURAL PROTEIN
1v2j:T (GLN30) to (SER54) BENZAMIDINE IN COMPLEX WITH BOVINE TRYPSIN VARIANT X(SSRI) BT.C1 | SERINE PROTEASE, HYDROLASE, SERINE PROTEINASE
1v2o:T (GLN30) to (SER54) TRYPSIN INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN VARIANT X(SSYI)BT.B4 | SERINE PROTEASE, HYDROLASE, SERINE PROTEINASE
1v2s:T (GLN30) to (SER54) BENZAMIDINE IN COMPLEX WITH BOVINE TRYPSIN VARIANT X(SSFI.GLU)BT.D1 | SERINE PROTEASE, HYDROLASE, SERINE PROTEINASE
1v2t:T (GLN30) to (SER54) TRYPSIN INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN VARIANT X(SSFI.GLU)BT.B4 | SERINE PROTEASE, HYDROLASE, SERINE PROTEINASE
1v2u:T (GLN30) to (SER54) BENZAMIDINE IN COMPLEX WITH BOVINE TRYPSIN VARINAT X(SSAI) BT.D1 | SERINE PROTEASE, HYDROLASE, SERINE PROTEINASE
1v2v:T (GLN30) to (SER54) BENZAMIDINE IN COMPLEX WITH BOVINE TRYPSIN VARIANT X(SSAI) BT.C1 | SERINE PROTEASE, HYDROLASE, SERINE PROTEINASE
1v2w:T (GLN30) to (SER54) TRYPSIN INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN VARIANT X(SSAI)BT.B4 | SERINE PROTEASE, HYDROLASE, SERINE PROTEINASE
2itk:A (PRO9) to (TRP34) HUMAN PIN1 BOUND TO D-PEPTIDE | PIN1, ISOMERASE, WW DOMAIN, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
2x7f:E (ILE24) to (ASP57) CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF HUMAN TRAF2- AND NCK-INTERACTING KINASE WITH WEE1CHK1 INHIBITOR | SERINE/THREONINE-PROTEIN KINASE, PHOSPHOPROTEIN, KINASE, TRANSFERASE
2iuk:A (ASN65) to (GLU112) CRYSTAL STRUCTURE OF SOYBEAN LIPOXYGENASE-D | IRON, DIOXYGENASE, METAL-BINDING, OXIDOREDUCTASE, OXYLIPIN BIOSYNTHESIS, SOYBEAN LIPOXYGENASE-D, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS
1v6b:A (LEU32) to (ALA70) SOLUTION STRUCTURE OF THE THIRD PDZ DOMAIN OF MOUSE HARMONIN | STRUCTURAL GENOMICS, USHER SYNDROME, USH1, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, PROTEIN BINDING
1v6d:A (GLN30) to (SER54) THE CRYSTAL STRUCTURE OF THE TRYPSIN COMPLEX WITH SYNTHETIC HETEROCHIRAL PEPTIDE | TRYPSIN COMPLEX, SYNTHETIC PEPTIDE, HYDROLASE
2x9a:A (ASN19) to (GLY40) CRYSTAL STRUCTURE OF G3P FROM PHAGE IF1 IN COMPLEX WITH ITS CORECEPTOR, THE C-TERMINAL DOMAIN OF TOLA | TRANSMEMBRANE, PHAGE INFECTION, PHAGE RECOGNITION, HOST-VIRUS INTERACTION, VIRION, VIRAL PROTEIN, HOST MEMBRANE
2x9a:C (ASN19) to (GLY40) CRYSTAL STRUCTURE OF G3P FROM PHAGE IF1 IN COMPLEX WITH ITS CORECEPTOR, THE C-TERMINAL DOMAIN OF TOLA | TRANSMEMBRANE, PHAGE INFECTION, PHAGE RECOGNITION, HOST-VIRUS INTERACTION, VIRION, VIRAL PROTEIN, HOST MEMBRANE
2x9f:A (TYR614) to (LEU649) EPHB4 KINASE DOMAIN INHIBITOR COMPLEX | TRANSFERASE, ATP-BINDING, GLYCOPROTEIN, TRANSMEMBRANE
1jbj:A (LEU113) to (LYS140) CD3 EPSILON AND GAMMA ECTODOMAIN FRAGMENT COMPLEX IN SINGLE- CHAIN CONSTRUCT | BETA-SHEET, C2-SET IMMUNOGLOBULIN SUPERFAMILY, H-BONDED G STRAND PAIR, SINGLE-CHAIN, IMMUNE SYSTEM
2ivw:A (GLY99) to (VAL122) THE SOLUTION STRUCTURE OF A DOMAIN FROM THE NEISSERIA MENINGITIDIS PILP PILOT PROTEIN. | LIPOPROTEIN, PILUS BIOGENESIS, NEISSERIA MENINGITIDIS, SECRETIN, PILOT PROTEIN
3woi:A (VAL64) to (ASN84) CRYSTAL STRUCTURE OF THE DAP BII (S657A) | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE
3woi:B (VAL64) to (ASN84) CRYSTAL STRUCTURE OF THE DAP BII (S657A) | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE
3woj:A (VAL64) to (ASN84) CRYSTAL STRUCTURE OF THE DAP BII | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE
1jdy:B (SER371) to (LEU391) RABBIT MUSCLE PHOSPHOGLUCOMUTASE | PHOSPHOGLUCOMUTASE, PHOSPHOTRANSFERASE
3wok:A (VAL64) to (ASN84) CRYSTAL STRUCTURE OF THE DAP BII (SPACE) | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE
1vaz:A (ASP9) to (TYR31) SOLUTION STRUCTURES OF THE P47 SEP DOMAIN | BETA-BETA-BETA-ALPHA-ALPHA-BETA, NOVEL FOLD, LIPID BINDING PROTEIN
3wom:B (ASP195) to (ALA240) CRYSTAL STRUCTURE OF THE DAP BII DIPEPTIDE COMPLEX II | CHYMOTRYPSIN FOLD, HYDROLASE
2ixc:B (MET1) to (GLU28) RMLC M. TUBERCULOSIS WITH DTDP-RHAMNOSE | ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS, EPIMERISE, EPIMERASE, EPIMERIZE
1jeq:B (ASP388) to (MET427) CRYSTAL STRUCTURE OF THE KU HETERODIMER | DOUBLE-STRAND DNA BREAK REPAIR, NON-HOMOLOGOUS END-JOINING, ALPHA/BETA DOMAIN, BETA BARREL, HELICAL C-TERMINAL ARM, SAP DOMAIN, DNA BINDING PROTEIN
3woo:A (ASP195) to (ALA240) CRYSTAL STRUCTURE OF THE DAP BII HEXAPEPTIDE COMPLEX I | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE-HORMONE COMPLEX
3woq:A (VAL64) to (ASN84) CRYSTAL STRUCTURE OF THE DAP BII HEXAPEPTIDE COMPLEX III | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE-HORMONE COMPLEX
3woq:B (VAL64) to (ASN84) CRYSTAL STRUCTURE OF THE DAP BII HEXAPEPTIDE COMPLEX III | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE-HORMONE COMPLEX
2iy5:B (PHE624) to (ALA654) PHENYLALANYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH TRNA AND A PHENYLALANYL-ADENYLATE ANALOG | CLASS II AMINOACYL-TRNA SYNTHETASE, LIGASE, RBD DOMIN, MAGNESIUM, SH3 DOMAIN, PHENYLALANYL-TRNA SYNTHETASE, THERMUS THERMOPHILUS, PROTEIN BIOSYNTHESIS, METAL-BINDING, NUCLEOTIDE-BINDING, RNA-BINDING, ATP-BINDING, TRNA-BINDING, HELIX-TURN-HELIX MOTIF, AMINOACYL-TRNA SYNTHETASE
2xbv:A (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH A PYRROLIDINE-3,4-DICARBOXYLIC ACID INHIBITOR | BLOOD CLOTTING, COAGULATION FACTOR, HYDROLASE, HYDROXYLATION, SERINE PROTEASE, ZYMOGEN
2xbw:A (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH A PYRROLIDINE-3,4-DICARBOXYLIC ACID INHIBITOR | BLOOD CLOTTING, COAGULATION FACTOR, HYDROLASE, HYDROXYLATION, SERINE PROTEASE, ZYMOGEN
2xbx:A (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH A PYRROLIDINE-3,4-DICARBOXYLIC ACID INHIBITOR | BLOOD CLOTTING, COAGULATION, COAGULATION FACTOR, HYDROLASE, HYDROXYLATION, SERINE PROTEASE, ZYMOGEN
2xby:A (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH A PYRROLIDINE-3,4-DICARBOXYLIC ACID INHIBITOR | BLOOD CLOTTING, COAGULATION, COAGULATION FACTOR, HYDROLASE, HYDROXYLATION, SERINE PROTEASE, ZYMOGEN
3wor:A (VAL64) to (ASN84) CRYSTAL STRUCTURE OF THE DAP BII OCTAPEPTIDE COMPLEX | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE-HORMONE COMPLEX
3wp9:A (THR15) to (GLY32) CRYSTAL STRUCTURE OF ANTIFREEZE PROTEIN FROM AN ANTARCTIC SEA ICE BACTERIUM COLWELLIA SP. | RIGHT-HANDED BETA-HELIX, ANTIFREEZE PROTEIN
5ann:A (TYR157) to (LEU198) STRUCTURE OF FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS | HYDROLASE, DIMERIZATION, QUATERNARY, XANTHOPHYLLOMYCES DENDR GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, PROTEIN CONFORMATION, SUBSTRATE SPECIFICITY, INVERTASE, PREBIOTICS
5ann:A (ASP246) to (LEU279) STRUCTURE OF FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS | HYDROLASE, DIMERIZATION, QUATERNARY, XANTHOPHYLLOMYCES DENDR GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, PROTEIN CONFORMATION, SUBSTRATE SPECIFICITY, INVERTASE, PREBIOTICS
5ann:B (TYR157) to (LEU198) STRUCTURE OF FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS | HYDROLASE, DIMERIZATION, QUATERNARY, XANTHOPHYLLOMYCES DENDR GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, PROTEIN CONFORMATION, SUBSTRATE SPECIFICITY, INVERTASE, PREBIOTICS
5ann:B (ASP246) to (LEU279) STRUCTURE OF FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS | HYDROLASE, DIMERIZATION, QUATERNARY, XANTHOPHYLLOMYCES DENDR GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, PROTEIN CONFORMATION, SUBSTRATE SPECIFICITY, INVERTASE, PREBIOTICS
1vcp:B (CYS119) to (PRO143) SEMLIKI FOREST VIRUS CAPSID PROTEIN (CRYSTAL FORM I) | VIRUS COAT PROTEIN, POLYPROTEIN, TRANSMEMBRANE, GLYCOPROTEIN, NUCLEOCAPSID PROTEIN, VIRAL PROTEIN
1vcp:C (CYS119) to (PRO143) SEMLIKI FOREST VIRUS CAPSID PROTEIN (CRYSTAL FORM I) | VIRUS COAT PROTEIN, POLYPROTEIN, TRANSMEMBRANE, GLYCOPROTEIN, NUCLEOCAPSID PROTEIN, VIRAL PROTEIN
2xc5:A (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH A PYRROLIDINE-3,4-DICARBOXYLIC ACID INHIBITOR | BLOOD CLOTTING, COAGULATION, COAGULATION FACTOR, HYDROLASE, HYDROXYLATION, SERINE PROTEASE, ZYMOGEN
5ao6:A (ARG76) to (THR96) ENDO180 D1-4, TRIGONAL FORM | ENDOCYTOSIS, ENDOCYTIC RECEPTOR, FIBRONECTIN TYPE II DOMAIN, C-TYPE LECTIN DOMAIN, COLLAGEN, GELATIN
2j0j:A (LEU272) to (LEU293) CRYSTAL STRUCTURE OF A FRAGMENT OF FOCAL ADHESION KINASE CONTAINING THE FERM AND KINASE DOMAINS. | CELL MIGRATION, FERM, TRANSFERASE, INTEGRIN SIGNALING
2j0k:B (VAL270) to (LEU293) CRYSTAL STRUCTURE OF A FRAGMENT OF FOCAL ADHESION KINASE CONTAINING THE FERM AND KINASE DOMAINS. | CELL MIGRATION, TRANSFERASE, INTEGRIN SIGNALING
4mpc:A (GLN341) to (PRO372) CRYSTAL STRUCTURE OF PYRUVATE DEHYDROGENASE KINASE ISOFORM 2 IN COMPLEX WITH INHIBITOR PS2 | GHKL PROTEIN KINASE, PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL PROTEIN KINASES, IMPAIRED GLUCOSE OXIDATION, HEPATIC STEATOSIS, TYPE 2 DIABETES, CANCER, BERGERAT NUCLEOTIDE-BINDING FOLD, PROTEIN KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2j34:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX | GAMMA- CARBOXYGLUTAMIC ACID, SERINE PROTEASE, EGF-LIKE DOMAIN, BLOOD COAGULATION, POLYMORPHISM, GLYCOPROTEIN, HYDROXYLATION, GAMMA-CARBOXYGLUTAMIC ACID, CALCIUM, ZYMOGEN, COMPLEX, PROTEASE, HYDROLASE
2j38:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX | GAMMA- CARBOXYGLUTAMIC ACID, SERINE PROTEASE, EGF-LIKE DOMAIN, BLOOD COAGULATION, POLYMORPHISM, GLYCOPROTEIN, HYDROXYLATION, GAMMA-CARBOXYGLUTAMIC ACID, CALCIUM, ZYMOGEN, COMPLEX, PROTEASE, HYDROLASE
1jkn:A (ARG15) to (MET42) SOLUTION STRUCTURE OF THE NUDIX ENZYME DIADENOSINE TETRAPHOSPHATE HYDROLASE FROM LUPINUS ANGUSTIFOLIUS COMPLEXED WITH ATP | ALPHA-BETA-ALPHA SANDWICH, ENZYME-SUBSTRATE COMPLEX, HYDROLASE
2xfc:F (TYR1) to (PRO40) THE CHIKUNGUNYA E1 E2 ENVELOPE GLYCOPROTEIN COMPLEX FIT INTO THE SEMLIKI FOREST VIRUS CRYO-EM MAP | VIRUS, RECEPTOR BINDING, MEMBRANE FUSION, ICOSAHEDRAL ENVELOPED VIRUS
1vhy:A (GLU38) to (LEU71) CRYSTAL STRUCTURE OF HAEMOPHILUS INFLUENZAE PROTEIN HI0303, PFAM DUF558 | PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
1jm6:B (GLN1333) to (PRO1364) PYRUVATE DEHYDROGENASE KINASE, ISOZYME 2, CONTAINING ADP | KINASE, MITOCHONDION, SERINE KINASE, TRANSFERASE
1jnp:A (ARG17) to (PRO36) CRYSTAL STRUCTURE OF MURINE TCL1 AT 2.5 RESOLUTION | BETA BARREL, DIMER, IMMUNE SYSTEM
3wsj:A (ARG10) to (PRO41) HTLV-1 PROTEASE IN COMPLEX WITH THE HIV-1 PROTEASE INHIBITOR INDINAVIR | RETROVIRAL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1vkl:A (SER371) to (LEU391) RABBIT MUSCLE PHOSPHOGLUCOMUTASE | PHOSPHOGLUCOMUTASE, PHOSPHOTRANSFERASE
1vkl:B (SER371) to (LEU391) RABBIT MUSCLE PHOSPHOGLUCOMUTASE | PHOSPHOGLUCOMUTASE, PHOSPHOTRANSFERASE
1jnr:A (ARG173) to (ALA207) STRUCTURE OF ADENYLYLSULFATE REDUCTASE FROM THE HYPERTHERMOPHILIC ARCHAEOGLOBUS FULGIDUS AT 1.6 RESOLUTION | SULFUR METABOLISM/ ADENYLYLSULFATE REDUCTASE/ IRON-SULFUR FLAVOPROTEIN/ CRYSTAL STRUCTURE/CATALYSIS, OXIDOREDUCTASE
1jnr:C (ARG173) to (ALA207) STRUCTURE OF ADENYLYLSULFATE REDUCTASE FROM THE HYPERTHERMOPHILIC ARCHAEOGLOBUS FULGIDUS AT 1.6 RESOLUTION | SULFUR METABOLISM/ ADENYLYLSULFATE REDUCTASE/ IRON-SULFUR FLAVOPROTEIN/ CRYSTAL STRUCTURE/CATALYSIS, OXIDOREDUCTASE
1jnz:A (ARG173) to (ALA207) STRUCTURE OF ADENYLYLSULFATE REDUCTASE FROM THE HYPERTHERMOPHILIC ARCHAEOGLOBUS FULGIDUS AT 1.6 RESOLUTION | SULFUR METABOLISM, ADENYLYLSULFATE REDUCTASE, IRON-SULFUR FLAVOPROTEIN, CRYSTAL STRUCTURE, CATALYSIS, OXIDOREDUCTASE
1jnz:C (ARG2173) to (ALA2207) STRUCTURE OF ADENYLYLSULFATE REDUCTASE FROM THE HYPERTHERMOPHILIC ARCHAEOGLOBUS FULGIDUS AT 1.6 RESOLUTION | SULFUR METABOLISM, ADENYLYLSULFATE REDUCTASE, IRON-SULFUR FLAVOPROTEIN, CRYSTAL STRUCTURE, CATALYSIS, OXIDOREDUCTASE
4mtb:A (GLN30) to (SER54) BOVINE TRYPSIN IN COMPLEX WITH SMALL MOLECULE INHIBITOR | METAL-BINDING, DIGESTION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2j6k:G (ASN28) to (ASN52) N-TERMINAL SH3 DOMAIN OF CMS (CD2AP HUMAN HOMOLOG) | PHOSPHORYLATION, ADAPTOR PROTEIN, EGFR DOWNREGULATION, SH3, SH3 DOMAIN, SH3-BINDING, CD2 ASSOCIATED PROTEIN, CYTOSKELETAL REARRANGEMENTS, SURFACE ACTIVE PROTEIN, SIGNALING PROTEIN, PROTEIN BINDING
3wsz:A (LEU220) to (MET243) SORLA VPS10P DOMAIN IN COMPLEX WITH ABETA-DERIVED PEPTIDE | BETA-PROPELLER, RECEPTOR, PROTEIN BINDING
3wsz:A (LEU503) to (GLU532) SORLA VPS10P DOMAIN IN COMPLEX WITH ABETA-DERIVED PEPTIDE | BETA-PROPELLER, RECEPTOR, PROTEIN BINDING
3wt3:A (TYR158) to (ILE202) NEW CRYSTAL FORM OF A HYPERTHERMOPHILIC ENDOCELLULASE | BETA-JELLY ROLL, GLYCOSIDE HYDROLASE, HYDROLASE
3wt3:B (TYR158) to (ILE202) NEW CRYSTAL FORM OF A HYPERTHERMOPHILIC ENDOCELLULASE | BETA-JELLY ROLL, GLYCOSIDE HYDROLASE, HYDROLASE
2xi1:A (GLN125) to (LEU145) CRYSTAL STRUCTURE OF THE HIV-1 NEF SEQUENCED FROM A PATIENT'S SAMPLE | VIRAL PROTEIN, AIDS
2xi1:B (GLN125) to (LEU145) CRYSTAL STRUCTURE OF THE HIV-1 NEF SEQUENCED FROM A PATIENT'S SAMPLE | VIRAL PROTEIN, AIDS
4mvn:C (VAL19) to (THR36) CRYSTAL STRUCTURE OF THE STAPHYLOCOCCAL SERINE PROTEASE SPLA IN COMPLEX WITH A SPECIFIC PHOSPHONATE INHIBITOR | CHYMOTRYPSIN-LIKE FOLD, SERINE ENDOPEPTIDASE, EXTRACELLULAR STAPHYLOCOCCAL PROTEASES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2xk3:A (ASP7) to (GLY42) STRUCTURE OF NEK2 BOUND TO AMINOPYRAZINE COMPOUND 35 | TRANSFERASE, CENTROSOME, MITOSIS
2xk4:A (ASP7) to (GLY42) STRUCTURE OF NEK2 BOUND TO AMINOPYRAZINE COMPOUND 17 | TRANSFERASE, CENTROSOME, MITOSIS
2xk6:A (ASP7) to (GLY42) STRUCTURE OF NEK2 BOUND TO AMINOPYRAZINE COMPOUND 36 | TRANSFERASE, CENTROSOME, MITOSIS
2xk7:A (ASP7) to (GLY42) STRUCTURE OF NEK2 BOUND TO AMINOPYRAZINE COMPOUND 23 | TRANSFERASE, CENTROSOME, MITOSIS
2xk8:A (ASP7) to (GLY42) STRUCTURE OF NEK2 BOUND TO AMINOPYRAZINE COMPOUND 15 | TRANSFERASE, CENTROSOME, MITOSIS
2xkc:A (ASP7) to (GLY42) STRUCTURE OF NEK2 BOUND TO AMINOPYRAZINE COMPOUND 14 | TRANSFERASE, CENTROSOME, MITOSIS
2xke:A (ASP7) to (GLY42) STRUCTURE OF NEK2 BOUND TO AMINIPYRAZINE COMPOUND 5 | TRANSFERASE, CENTROSOME, MITOSIS
2xkf:A (ASP7) to (GLY42) STRUCTURE OF NEK2 BOUND TO AMINOPYRAZINE COMPOUND 2 | TRANSFERASE, CENTROSOME, MITOSIS
1vr1:H (GLN30) to (THR54) SPECIFITY FOR PLASMINOGEN ACTIVATOR INHIBITOR-1 | THROMBIN, BLOOD CLOTTING-HYDROLASE INHIBITOR COMPLEX
3wwg:B (MET232) to (LYS250) CRYSTAL STRUCTURE OF THE N-GLYCAN-DEFICIENT VARIANT N448A OF ISOPULLULANASE COMPLEXED WITH ISOPANOSE | BETA-HELIX, GLYCOSIDE HYDROLASE FAMILY 49, HYDROLASE
3wwj:A (LEU209) to (LYS231) CRYSTAL STRUCTURE OF AN ENGINEERED SITAGLIPTIN-PRODUCING TRANSAMINASE, ATA-117-RD11 | TRANSAMINASE, AMINE-PYRUVATE AMINOTRANSFERASE, PYRIDOXAL-5'- PHOSPHATE, MULTI-DOMAIN PROTEIN (ALPHA AND BETA), FOLD CLASS IV PLP- DEPENDENT ENZYME, TRANSFERASE
3wwj:E (LEU209) to (LYS231) CRYSTAL STRUCTURE OF AN ENGINEERED SITAGLIPTIN-PRODUCING TRANSAMINASE, ATA-117-RD11 | TRANSAMINASE, AMINE-PYRUVATE AMINOTRANSFERASE, PYRIDOXAL-5'- PHOSPHATE, MULTI-DOMAIN PROTEIN (ALPHA AND BETA), FOLD CLASS IV PLP- DEPENDENT ENZYME, TRANSFERASE
3wwj:H (LEU209) to (LYS231) CRYSTAL STRUCTURE OF AN ENGINEERED SITAGLIPTIN-PRODUCING TRANSAMINASE, ATA-117-RD11 | TRANSAMINASE, AMINE-PYRUVATE AMINOTRANSFERASE, PYRIDOXAL-5'- PHOSPHATE, MULTI-DOMAIN PROTEIN (ALPHA AND BETA), FOLD CLASS IV PLP- DEPENDENT ENZYME, TRANSFERASE
2j9n:A (GLN30) to (SER52) ROBOTICALLY HARVESTED TRYPSIN COMPLEXED WITH BENZAMIDINE CONTAINING POLYPEPTIDE MEDIATED CRYSTAL CONTACTS | ROBOTIC HARVEST, INTERMOLECULAR CONTACTS, TRYPSIN, CALCIUM, ZYMOGEN, PROTEASE, DIGESTION, SALMON PROTAMINE PEPTIDES, HYDROLASE, BENZAMIDINE, METAL-BINDING, SERINE PROTEASE
3wx7:A (ASP394) to (LEU427) CRYSTAL STRUCTURE OF COD | OLIGOSACCHARIDE DEACETYLACE, CARBOHYDRATE-BINDING, HYDROLASE
3wx7:B (ASP394) to (LEU427) CRYSTAL STRUCTURE OF COD | OLIGOSACCHARIDE DEACETYLACE, CARBOHYDRATE-BINDING, HYDROLASE
1vyu:A (LYS96) to (SER120) BETA3 SUBUNIT OF VOLTAGE-GATED CA2+-CHANNEL | CALCIUM CHANNEL BETA SUBUNIT, AID DOAMIN, ION TRANSPORT, IONIC CHANNEL, VOLTAGE-GATED CHANNEL, SH3 DOMAIN
5ayf:A (ARG215) to (GLY247) CRYSTAL STRUCTURE OF SET7/9 IN COMPLEX WITH CYPROHEPTADINE | SET DOMAIN, METHYLTRANSFERASE, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mzh:A (ARG57) to (ASP92) CRYSTAL STRUCTURE OF HUMAN SPINDLIN1 BOUND TO HISTONE H3(K4ME3-R8ME2S) PEPTIDE | WNT SIGNAL, HISTONE H3, NUCLEAR, GENE REGULATION
4mzm:A (GLY5) to (GLY48) MAZF FROM S. AUREUS CRYSTAL FORM I, P212121, 2.1 A | CCDB/MAZF FOLD, RIBONUCLEASE, MAZE, MRNA INTERFERASE, HYDROLASE
4mzm:B (GLY5) to (GLY48) MAZF FROM S. AUREUS CRYSTAL FORM I, P212121, 2.1 A | CCDB/MAZF FOLD, RIBONUCLEASE, MAZE, MRNA INTERFERASE, HYDROLASE
4mzm:D (GLY5) to (GLY48) MAZF FROM S. AUREUS CRYSTAL FORM I, P212121, 2.1 A | CCDB/MAZF FOLD, RIBONUCLEASE, MAZE, MRNA INTERFERASE, HYDROLASE
4mzp:A (GLY5) to (GLY48) MAZF FROM S. AUREUS CRYSTAL FORM III, C2221, 2.7 A | CCDB/MAZF FOLD, RIBONUCLEASE, MAZE, MRNA INTERFERASE, HYDROLASE
4mzp:B (GLY5) to (GLY48) MAZF FROM S. AUREUS CRYSTAL FORM III, C2221, 2.7 A | CCDB/MAZF FOLD, RIBONUCLEASE, MAZE, MRNA INTERFERASE, HYDROLASE
4mzp:C (GLY5) to (GLY48) MAZF FROM S. AUREUS CRYSTAL FORM III, C2221, 2.7 A | CCDB/MAZF FOLD, RIBONUCLEASE, MAZE, MRNA INTERFERASE, HYDROLASE
4mzp:D (GLY5) to (GLY48) MAZF FROM S. AUREUS CRYSTAL FORM III, C2221, 2.7 A | CCDB/MAZF FOLD, RIBONUCLEASE, MAZE, MRNA INTERFERASE, HYDROLASE
4mzp:E (GLY5) to (GLY48) MAZF FROM S. AUREUS CRYSTAL FORM III, C2221, 2.7 A | CCDB/MAZF FOLD, RIBONUCLEASE, MAZE, MRNA INTERFERASE, HYDROLASE
4mzp:F (GLY5) to (GLY48) MAZF FROM S. AUREUS CRYSTAL FORM III, C2221, 2.7 A | CCDB/MAZF FOLD, RIBONUCLEASE, MAZE, MRNA INTERFERASE, HYDROLASE
4mzp:G (GLY5) to (GLY48) MAZF FROM S. AUREUS CRYSTAL FORM III, C2221, 2.7 A | CCDB/MAZF FOLD, RIBONUCLEASE, MAZE, MRNA INTERFERASE, HYDROLASE
4mzp:H (GLY5) to (GLY48) MAZF FROM S. AUREUS CRYSTAL FORM III, C2221, 2.7 A | CCDB/MAZF FOLD, RIBONUCLEASE, MAZE, MRNA INTERFERASE, HYDROLASE
4mzt:A (GLY5) to (GLY48) MAZF FROM S. AUREUS CRYSTAL FORM II, C2221, 2.3 A | CCDB/MAZF FOLD, RIBONUCLEASE, MAZE, HYDROLASE
2xnn:A (ASP7) to (GLY42) STRUCTURE OF NEK2 BOUND TO CCT242430 | TRANSFERASE, CENTROSOME, MITOSIS, CELL CYCLE
2xnp:A (ASP7) to (GLY42) STRUCTURE OF NEK2 BOUND TO CCT244858 | TRANSFERASE, CENTROSOME, MITOSIS, CELL CYCLE
2xp3:A (PRO9) to (TRP34) DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION | ISOMERASE, PROLINE DIRECTED KINASE, CELL CYCLE, ONCOGENIC TRANSFORMATION
2xp6:A (PRO9) to (TRP34) DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION | ISOMERASE, PROLINE DIRECTED KINASE, CELL CYCLE, ONCOGENIC TRANSFORMATION
2xpa:A (PRO9) to (TRP34) DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION | ISOMERASE, ROTAMASE, PROLINE DIRECTED KINASE, CELL CYCLE, ONCOGENIC TRANSFORMATION
5b0w:D (GLY104) to (GLY122) CRYSTAL STRUCTURE OF THE 11-CIS ISOMER OF PHARAONIS HALORHODOPSIN IN THE ABSENCE OF HALIDE IONS | SEVEN TRANS-MEMBRANE HELICES, RETINYLIDENE PROTEIN, LIGHT-DRIVEN CHLORIDE ION PUMP MICROBIAL RHODOPSIN, MEMBRANE PROTEIN
5b0w:E (GLY104) to (GLY122) CRYSTAL STRUCTURE OF THE 11-CIS ISOMER OF PHARAONIS HALORHODOPSIN IN THE ABSENCE OF HALIDE IONS | SEVEN TRANS-MEMBRANE HELICES, RETINYLIDENE PROTEIN, LIGHT-DRIVEN CHLORIDE ION PUMP MICROBIAL RHODOPSIN, MEMBRANE PROTEIN
2jav:A (ASP7) to (GLY42) HUMAN KINASE WITH PYRROLE-INDOLINONE LIGAND | TRANSFERASE, PHOSPHORYLATION, NUCLEOTIDE-BINDING, ATP-BINDING, CELL DIVISION, METAL-BINDING, NUCLEAR PROTEIN, SERINE/THREONINE-PROTEIN KINASE, SERINE/THREONINE PROTEIN KINASE, KINASE, MEIOSIS, MITOSIS, MAGNESIUM, CELL CYCLE
3x2u:A (GLN42) to (ASP75) MICHAELIS-LIKE INITIAL COMPLEX OF CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT. | MICHAELIS-LIKE COMPLEX, PROTEIN-SUBSTRATE, PKAC-ATPMG2 TERNARY, SER/THR KINASE, ATP BINDING, PHOSPHORYLATION, TRANSFERASE-PEPTIDE COMPLEX
3x37:A (GLY46) to (TYR71) CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SLD7 IN COMPLEX WITH SLD3 | BETA-BARREL, REPLICATION REGULATOR
2xrc:A (GLN336) to (THR359) HUMAN COMPLEMENT FACTOR I | IMMUNE SYSTEM, HYDROLASE, CONGLUTINOGEN ACTIVATING FACTOR, SERINE PROTEASE, COMPLEMENT SYSTEM
2xrc:B (GLN336) to (THR359) HUMAN COMPLEMENT FACTOR I | IMMUNE SYSTEM, HYDROLASE, CONGLUTINOGEN ACTIVATING FACTOR, SERINE PROTEASE, COMPLEMENT SYSTEM
2xrc:C (GLN336) to (THR359) HUMAN COMPLEMENT FACTOR I | IMMUNE SYSTEM, HYDROLASE, CONGLUTINOGEN ACTIVATING FACTOR, SERINE PROTEASE, COMPLEMENT SYSTEM
2xrc:D (GLN336) to (THR359) HUMAN COMPLEMENT FACTOR I | IMMUNE SYSTEM, HYDROLASE, CONGLUTINOGEN ACTIVATING FACTOR, SERINE PROTEASE, COMPLEMENT SYSTEM
3j9u:A (ILE197) to (PRO216) YEAST V-ATPASE STATE 2 | V-ATPASE, V-TYPE ATPASE, VACUOLAR-TYPE ATPASE, PROTON PUMP, HYDROLASE
1w3f:A (ASN94) to (SER122) CRYSTAL STRUCTURE OF THE HEMOLYTIC LECTIN FROM THE MUSHROOM LAETIPORUS SULPHUREUS COMPLEXED WITH N-ACETYLLACTOSAMINE IN THE GAMMA MOTIF | TOXIN/LECTIN, PORE-FORMING TOXIN, HEMOLYTIC LECTIN, OLIGOMER, BETA-TREFOIL
2je8:A (PRO678) to (GLN704) STRUCTURE OF A BETA-MANNOSIDASE FROM BACTEROIDES THETAIOTAOMICRON | BETA-MANNOSIDASE, GLYCOSIDE HYDROLASE, HYDROLASE
2je8:B (PRO678) to (GLN704) STRUCTURE OF A BETA-MANNOSIDASE FROM BACTEROIDES THETAIOTAOMICRON | BETA-MANNOSIDASE, GLYCOSIDE HYDROLASE, HYDROLASE
5b7i:A (ARG980) to (ASP1008) CAS3-ACRF3 COMPLEX | DNA NUCLEASE, PHAGY PROTEIN, ANTI-CRISPR, HYDROLASE-UNKNOWN FUNCTION COMPLEX
5bn4:A (LYS111) to (VAL146) STRUCTURE OF A UNIQUE ATP SYNTHASE NEQA-NEQB IN COMPLEX WITH ANP FROM NANOARCHEAUM EQUITANS | ATP SYNTHASE, NANOARCHEAUM EQUITANS, CATALYTIC CORE, HYDROLASE
5bnb:A (GLY57) to (VAL96) CRYSTAL STRUCTURE OF A UBE2S-UBIQUITIN CONJUGATE | UBIQUITIN-CONJUGATING ENZYME, E2 ENZYME, UBC DOMAIN, UBIQUITINATION, CELL CYCLE
2xtt:B (GLN30) to (SER54) BOVINE TRYPSIN IN COMPLEX WITH EVOLUTIONARY ENHANCED SCHISTOCERCA GREGARIA PROTEASE INHIBITOR 1 (SGPI-1-P02) | HYDROLASE, CATALYTIC MECHANISM, INHIBITION, IN VITRO EVOLUTION
2jgd:A (ALA628) to (LEU659) E. COLI 2-OXOGLUTARATE DEHYDROGENASE (E1O) | 2-OXOGLUTARATE DEHYDROGENASE, FLAVOPROTEIN, OXIDOREDUCTASE, THIAMINE DIPHOSPHATE, THIAMINE PYROPHOSPHATE, ADENOSINE MONOPHOSPHATE, E1O, KGDH, OGDH, GLYCOLYSIS, OXALOACETATE
2jgd:B (ALA628) to (ASP656) E. COLI 2-OXOGLUTARATE DEHYDROGENASE (E1O) | 2-OXOGLUTARATE DEHYDROGENASE, FLAVOPROTEIN, OXIDOREDUCTASE, THIAMINE DIPHOSPHATE, THIAMINE PYROPHOSPHATE, ADENOSINE MONOPHOSPHATE, E1O, KGDH, OGDH, GLYCOLYSIS, OXALOACETATE
2xu1:D (VAL168) to (ASP204) CATHEPSIN L WITH A NITRILE INHIBITOR | HYDROLASE, DRUG DESIGN, THIOL PROTEASE
1w7g:H (GLN30) to (THR54) ALPHA-THROMBIN COMPLEX WITH SULFATED HIRUDIN (RESIDUES 54-65) AND L- ARGININE TEMPLATE INHIBITOR CS107 | BLOOD COAGULATION-INHIBITOR, THROMBIN, ARGATROBAN, SERINE PROTEASE, COAGULATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2jh0:D (GLN30) to (THR54) HUMAN THROMBIN HIRUGEN INHIBITOR COMPLEX | GLYCOPROTEIN, SERINE PROTEASE, KRINGLE, ZYMOGEN, THROMBIN, PROTEASE, DISEASE MUTATION, BLOOD COAGULATION, GAMMA-CARBOXYGLUTAMIC ACID, PROTEASE INHIBITOR, SERINE PROTEASE INHIBITOR, SULFATION, ACUTE PHASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5bom:A (GLY290) to (ASP314) DNA POLYMERASE BETA BINARY COMPLEX WITH A TEMPLATING 5CLC | TRANSFERASE, LYASE/DNA, LYASE-DNA COMPLEX
3zew:B (VAL615) to (LEU649) CRYSTAL STRUCTURE OF EPHB4 IN COMPLEX WITH STAUROSPORINE | TRANSFERASE, INHIBITOR
3zfx:B (VAL619) to (LEU653) CRYSTAL STRUCTURE OF EPHB1 | TRANSFERASE
3zfx:F (VAL619) to (LEU653) CRYSTAL STRUCTURE OF EPHB1 | TRANSFERASE
5bp2:C (ALA979) to (ALA1010) DEHYDRATASE DOMAIN (DH) OF THE MYCOCEROSIC ACID SYNTHASE (MAS), CRYSTAL FORM 1 | LYASE, PKS, DEHYDRATASE, DH, POLYKETIDE
4n8x:S (GLY8) to (ASN46) THE STRUCTURE OF NOSTOC SP. PCC 7120 CCML | CCML, STRANDED BETA BARREL, BACTERIAL MICROCOMPARTMENT VERTEX PROTEIN, CARBOXYSOME, STRUCTURAL PROTEIN
1w8b:H (GLN30) to (SER54) FACTOR7 - 413 COMPLEX | SERINE PROTEASE, COAGULATION, ENZYME COMPLEX, HYDROLASE
1jzd:C (ALA17) to (TYR42) DSBC-DSBDALPHA COMPLEX | THIOL DISULFIDE OXIDOREDUCTASE, REACTION INTERMEDIATE, PROTEIN-PROTEIN COMPLEX
2xvl:A (THR809) to (ASP831) CRYSTAL STRUCTURE OF ALPHA-XYLOSIDASE (GH31) FROM CELLVIBRIO JAPONICUS IN COMPLEX WITH PENTAERYTHRITOL PROPOXYLATE (5 4 PO OH) | HYDROLASE, GLYCOSYL HYDROLASE FAMILY 31, (BETA/ALPHA)8 BARREL
4n9f:4 (GLU41) to (PRO92) CRYSTAL STRUCTURE OF THE VIF-CBFBETA-CUL5-ELOB-ELOC PENTAMERIC COMPLEX | ZINC FINGER MOTIF, STABILIZE VIF INTERACTION WITH CUL5, CUL5, TRANSCRIPTION-VIRAL PROTEIN COMPLEX, LIGASE-VIRAL PROTEIN COMPLEX
2xw9:A (MET15) to (SER38) CRYSTAL STRUCTURE OF COMPLEMENT FACTOR D MUTANT S183A | IMMUNE SYSTEM, HYDROLASE, SERINE PROTEASE, ALTERNATIVE PATHWAY
2xwa:A (GLY185) to (THR214) CRYSTAL STRUCTURE OF COMPLEMENT FACTOR D MUTANT R202A | IMMUNE SYSTEM, HYDROLASE, SERINE PROTEASE, ALTERNATIVE PATHWAY
1k0z:A (GLY47) to (ASN73) CRYSTAL STRUCTURE OF THE PVUII ENDONUCLEASE WITH PR3+ AND SO4 IONS BOUND IN THE ACTIVE SITE AT 2.05A. | PVUII, ENDONUCLEASE, RESTRICTION ENZYME, CATALYSIS, IONS, XRAYS, LANTHANADES, HYDROLASE
1k0z:B (GLY47) to (ASN73) CRYSTAL STRUCTURE OF THE PVUII ENDONUCLEASE WITH PR3+ AND SO4 IONS BOUND IN THE ACTIVE SITE AT 2.05A. | PVUII, ENDONUCLEASE, RESTRICTION ENZYME, CATALYSIS, IONS, XRAYS, LANTHANADES, HYDROLASE
1k1i:A (GLN30) to (SER54) BOVINE TRYPSIN-INHIBITOR COMPLEX | HYDROLASE,SERINE PROTEASE
1k1j:A (GLN30) to (SER54) BOVINE TRYPSIN-INHIBITOR COMPLEX | HYDROLASE, SERINE PROTEASE
1k1l:A (GLN30) to (SER54) BOVINE TRYPSIN-INHIBITOR COMPLEX | HYDROLASE, SERINE PROTEASE
1k1m:A (GLN30) to (SER54) BOVINE TRYPSIN-INHIBITOR COMPLEX | HYDROLASE, SERINE PROTEINASE
1k1n:A (GLN30) to (SER54) BOVINE TRYPSIN-INHIBITOR COMPLEX | HYDROLASE, SERINE PROTEINASE
1k22:H (GLN30) to (THR54) HUMAN THROMBIN-INHIBITOR COMPLEX | COMPLEX (SERINE PROTEASE-INHIBITOR), HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1k24:A (SER105) to (PHE163) CRYSTAL STRUCTURE OF THE OPCA OUTER MEMBRANE ADHESIN/INVASIN FROM NEISSERIA MENINGITIDIS | ADHESIN, INVASIN, MEMBRANE PROTEIN, OUTER MEMBRANE, BETA BARREL
5bsx:A (GLY332) to (TRP381) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH DISINFECTANT PUREGREEN24 | CITRATE, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
5bsy:A (LEU482) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH LEMON JUICE | CITRATE, LEMON, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
5bsy:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH LEMON JUICE | CITRATE, LEMON, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
1wbg:B (GLN30) to (LEU53) ACTIVE SITE THROMBIN INHIBITORS | BLOOD COAGULATION-INHIBITOR, SERINE PROTEASE, BLOOD COAGULATION, ACUTE PHASE, CALCIUM-BINDING, DISEASE MUTATION, GAMMA- CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, KRINGLE, POLYMORPHISME, VITAMIN K, ZYMOGEN, SULFATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2jkh:A (GLN30) to (THR54) FACTOR XA - CATION INHIBITOR COMPLEX | PLASMA, CALCIUM, ZYMOGEN, SECRETED, PROTEASE, HYDROLASE, POLYMORPHISM, GLYCOPROTEIN, GAMMA-CARBOXYGLUTAMIC ACID, BLOOD COAGULATION, COAGULATION FACTOR, HYDROXYLATION, SERINE PROTEASE, EGF-LIKE DOMAIN, CLEAVAGE ON PAIR OF BASIC RESIDUES
2xyn:A (ASP287) to (LEU319) HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680 | CELL ADHESION, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
1k5j:B (ILE18) to (LEU47) THE CRYSTAL STRUCTURE OF NUCLEOPLASMIN-CORE | BETA-BARREL, JELLYROLL, BETA-BULGE, PENTAMER, CHAPERONE
1k5j:C (ILE18) to (LEU47) THE CRYSTAL STRUCTURE OF NUCLEOPLASMIN-CORE | BETA-BARREL, JELLYROLL, BETA-BULGE, PENTAMER, CHAPERONE
1k5j:D (ILE18) to (LEU47) THE CRYSTAL STRUCTURE OF NUCLEOPLASMIN-CORE | BETA-BARREL, JELLYROLL, BETA-BULGE, PENTAMER, CHAPERONE
1k5r:A (GLY16) to (GLN40) YAP65 WW DOMAIN S24-AMINO-ETHYLSULFANYL-ACETIC ACID MUTANT | WW DOMAIN, YAP65, BETA-SHEET PROTEINS, STABILITY OF BETA SHEETS, SIGNALING PROTEIN
1k5v:B (LEU86) to (LEU135) HUMAN ACIDIC FIBROBLAST GROWTH FACTOR. 141 AMINO ACID FORM WITH AMINO TERMINAL HIS TAG WITH ASN106 REPLACED BY GLY (N106G). | BETA-TREFOIL, HORMONE/GROWTH FACTOR COMPLEX
4ne9:A (GLN454) to (SER485) PCSK9 IN COMPLEX WITH LDLR PEPTIDE | PCSK9, LDL RECEPTOR, AUTOCATALYTIC CLEAVAGE, CHOLESTEROL METABOLISM, HYDROLASE
4ne9:B (GLN454) to (SER485) PCSK9 IN COMPLEX WITH LDLR PEPTIDE | PCSK9, LDL RECEPTOR, AUTOCATALYTIC CLEAVAGE, CHOLESTEROL METABOLISM, HYDROLASE
5bvb:B (TYR84) to (PHE118) ENGINEERED DIGOXIGENIN BINDER DIG5.1A | ENGINEERED, COMPUTATIONALLY DESIGNED, DESIGNED, LIGAND BINDER, DIGOXIGENIN, DE NOVO PROTEIN
2jqf:R (GLU147) to (TYR168) FULL LENGTH LEADER PROTEASE OF FOOT AND MOUTH DISEASE VIRUS C51A MUTANT | CYSTEINE, PROTEASE, LEADER, FOOT AND MOUTH DISEASE VIRUS, OLIGIMERISATION, VIRAL PROTEIN
2jqf:S (GLU347) to (TYR368) FULL LENGTH LEADER PROTEASE OF FOOT AND MOUTH DISEASE VIRUS C51A MUTANT | CYSTEINE, PROTEASE, LEADER, FOOT AND MOUTH DISEASE VIRUS, OLIGIMERISATION, VIRAL PROTEIN
2jsn:A (ASP27) to (ALA55) SOLUTION STRUCTURE OF THE ATYPICAL PDZ-LIKE DOMAIN OF SYNBINDIN | PROTEIN INTERACTION, PROTEIN TRANSPORT
4nfw:K (MET1) to (GLN33) STRUCTURE AND ATYPICAL HYDROLYSIS MECHANISM OF THE NUDIX HYDROLASE ORF153 (YMFB) FROM ESCHERICHIA COLI | NUDIX HYDROLASE; YMFB; NUCLEOSIDE TRIPHOSPHATASE; METAL IONS-BASED CATALYSIS, NUDIX MOTIF, PHOPHATASE, HYDROLASE
2jwy:A (ASN115) to (PRO157) SOLUTION NMR STRUCTURE OF UNCHARACTERIZED LIPOPROTEIN YAJI FROM ESCHERICHIA COLI. NORTHEAST STRUCTURAL GENOMICS TARGET ER540 | LIPOPROTEIN, YAJI, STRUCTURAL GENOMICS, GFT NMR, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, MEMBRANE, PALMITATE, PSI-2, PROTEIN STRUCTURE INITIATIVE
4ng9:H (GLN30) to (SER54) FACTOR VIIA IN COMPLEX WITH THE INHIBITOR (2R)-2-[(1-AMINOISOQUINOLIN- 6-YL)AMINO]-2-[3-ETHOXY-4-(PROPAN-2-YLOXY)PHENYL]-N-(3- SULFAMOYLBENZYL)ETHANAMIDE | GLYCOPROTEIN, HYDROLASE, SERINE PROTEASE, PLASMA, BLOOD COAGULATION FACTOR, PROTEIN INHIBITOR COMPLEX, CALCIUM-BINDING, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
2k45:A (LEU85) to (LYS128) C2A DOMAIN OF SYNAPTOTOTAGMIN I SOLUTION STRUCTURE IN THE FGF-1-C2A BINARY COMPLEX: KEY COMPONENT IN THE FIBROBLAST GROWTHFACTOR NON-CLASSICAL PATHWAY | BETA BARREL, CALCIUM, CELL JUNCTION, CYTOPLASMIC VESICLE, GLYCOPROTEIN, LIPOPROTEIN, MEMBRANE, METAL-BINDING, PALMITATE, PHOSPHOPROTEIN, SYNAPSE, TRANSMEMBRANE, PROTEIN TRANSPORT
2k4a:B (GLU80) to (LEU128) FGF-1-C2A BINARY COMPLEX STRUCTURE: A KEY COMPONENT IN THE FIBROBLAST GROWTHFACTOR NON-CLASSICAL PATHWAY | BETA BARREL, FGF1-C2A BINARY COMPLEX, CALCIUM, CELL JUNCTION, CYTOPLASMIC VESICLE, GLYCOPROTEIN, LIPOPROTEIN, MEMBRANE, METAL-BINDING, PALMITATE, PHOSPHOPROTEIN, SYNAPSE, TRANSMEMBRANE, ACETYLATION, ANGIOGENESIS, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, GROWTH FACTOR, HEPARIN-BINDING, MITOGEN, POLYMORPHISM, PROTEIN TRANSPORT
4nhf:D (LYS153) to (GLY203) CRYSTAL STRUCTURE OF THE SOLUBLE DOMAIN OF TRWG TYPE IV SECRETION MACHINERY FROM BARTONELLA GRAHAMII | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, HOST-SPECIFIC INTERACTION, OUTER MEMBRANE PROTEIN, PATHOGENESIS, TYPE IV SECRETION SYSTEM, VIRB8, PROTEIN TRANSPORT
1wlt:A (PRO2) to (GLU29) CRYSTAL STRUCTURE OF DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE HOMOLOGUE FROM SULFOLOBUS TOKODAII | JELLY ROLL-LIKE TOPOLOGY, FLATTENED BARREL, ISOMERASE
2kc5:A (GLU81) to (MET111) SOLUTION STRUCTURE OF HYBE FROM ESCHERICHIA COLI | CHAPERONE
2kcq:A (THR106) to (ASP136) SOLUTION STRUCTURE OF PROTEIN SRU_2040 FROM SALINIBACTER RUBER (STRAIN DSM 13855) . NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SRR106 | NMR, NESG, STRUCTURE, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, UNKNOWN FUNCTION, NUCLEOTIDE-BINDING PROTEIN
1kca:D (SER139) to (PRO176) CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR C-TERMINAL DOMAIN OCTAMER | GENE REGULATION, DNA-BINDING, LAMBDA REPRESSOR, PROTEIN OLIGOMERIZATION, DNA-LOOPING
2ked:A (LYS24) to (PRO53) STRUCTURE OF SDF-1/CXCL12 | STROMAL CELL DERIVED FACTOR-1, SDF1-ALPHA, CXCL12, CHEMOKINE, ALTERNATIVE SPLICING, CHEMOTAXIS, CYTOKINE, GROWTH FACTOR, SECRETED
2kee:A (LYS24) to (LYS54) STRUCTURE OF SDF-1/CXCL12 | STROMAL CELL DERIVED FACTOR-1, SDF1-ALPHA, CXCL12, CHEMOKINE, ALTERNATIVE SPLICING, CHEMOTAXIS, CYTOKINE, GROWTH FACTOR, SECRETED
4nj5:A (ILE235) to (GLY275) CRYSTAL STRUCTURE OF SUVH9 | SET DOMAIN, ZINC BINDING MOTIF, ZINC BINDING, METAL BINDING PROTEIN
2ki4:A (GLU80) to (LEU128) FGF1-S100A13 COMPLEX STRUCTURE: KEY COMPONENT IN NON-CLASSICAL PATH WAY OF FGF1 | ACIDIC FIBROBLAST GROWTH FACTOR, S100A13, TETRAMERIC COMPLEX, ACETYLATION, ALTERNATIVE SPLICING, ANGIOGENESIS, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, GROWTH FACTOR, HEPARIN-BINDING, MITOGEN, POLYMORPHISM, CALCIUM, PROTEIN TRANSPORT
2ki4:D (GLU80) to (LEU128) FGF1-S100A13 COMPLEX STRUCTURE: KEY COMPONENT IN NON-CLASSICAL PATH WAY OF FGF1 | ACIDIC FIBROBLAST GROWTH FACTOR, S100A13, TETRAMERIC COMPLEX, ACETYLATION, ALTERNATIVE SPLICING, ANGIOGENESIS, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, GROWTH FACTOR, HEPARIN-BINDING, MITOGEN, POLYMORPHISM, CALCIUM, PROTEIN TRANSPORT
2ki6:B (GLU80) to (LEU128) THE FGF1-S100A13-C2A HETERO-HEXAMERIC COMPLEX STRUCTURE: A COMPONENT IN THE NON-CLASSICAL PATHWAY FOR FGF1 SECRETION | FGF1-S100A13-C2A HETERO-HEXAMERIC COMPLEX, FGF1, S100A13, C2A, CALCIUM, CELL JUNCTION, CYTOPLASMIC VESICLE, GLYCOPROTEIN, LIPOPROTEIN, MEMBRANE, METAL-BINDING, PALMITATE, PHOSPHOPROTEIN, SYNAPSE, TRANSMEMBRANE, ACETYLATION, ALTERNATIVE SPLICING, ANGIOGENESIS, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, GROWTH FACTOR, HEPARIN-BINDING, MITOGEN, POLYMORPHISM, PROTEIN TRANSPORT
2ki6:E (GLU80) to (LEU128) THE FGF1-S100A13-C2A HETERO-HEXAMERIC COMPLEX STRUCTURE: A COMPONENT IN THE NON-CLASSICAL PATHWAY FOR FGF1 SECRETION | FGF1-S100A13-C2A HETERO-HEXAMERIC COMPLEX, FGF1, S100A13, C2A, CALCIUM, CELL JUNCTION, CYTOPLASMIC VESICLE, GLYCOPROTEIN, LIPOPROTEIN, MEMBRANE, METAL-BINDING, PALMITATE, PHOSPHOPROTEIN, SYNAPSE, TRANSMEMBRANE, ACETYLATION, ALTERNATIVE SPLICING, ANGIOGENESIS, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, GROWTH FACTOR, HEPARIN-BINDING, MITOGEN, POLYMORPHISM, PROTEIN TRANSPORT
2kid:A (GLY74) to (GLY119) SOLUTION STRUCTURE OF THE S. AUREUS SORTASE A-SUBSTRATE COMPLEX | SORTASE, EIGHT STRANDED BETA BARREL, TRANSPEPTIDASE, ENZYME-SUBSTRATE COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1kd7:M (PRO156) to (GLY175) CRYSTAL STRUCTURE OF AN EXTRACELLULAR DOMAIN FRAGMENT OF HUMAN BAFF | BETA-SHEET SHANDWICH, TNF, MEMBRANE PROTEIN
4nk9:A (ARG477) to (LEU516) CRYSTAL STRUCTURE OF HUMAN FIBROBLAST GROWTH FACTOR RECEPTOR 1 KINASE DOMAIN IN COMPLEX WITH PYRAZOLAMINOPYRIMIDINE 1 | KINASE, ATP BINDING, PHOSPHORYLATION, TRANS-MEMBRANE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2y3v:B (ARG104) to (LEU137) N-TERMINAL HEAD DOMAIN OF DANIO RERIO SAS-6 | STRUCTURAL PROTEIN, CYTOSKELETON, BASAL BODY, CENTRIOLE, CARTWHEEL, CARTWHEEL HUB
2y3v:C (ARG104) to (LEU137) N-TERMINAL HEAD DOMAIN OF DANIO RERIO SAS-6 | STRUCTURAL PROTEIN, CYTOSKELETON, BASAL BODY, CENTRIOLE, CARTWHEEL, CARTWHEEL HUB
5c0m:B (ARG246) to (ALA280) CRYSTAL STRUCTURE OF SGF29 TANDEM TUDOR DOMAIN IN COMPLEX WITH A CARBA CONTAINING PEPTIDE | SGF29, TANDEM TUDOR DOMAIN, CARBA CONTAINING PEPTIDE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSCRIPTION
5c0p:A (ARG116) to (PRO146) THE CRYSTAL STRUCTURE OF ENDO-ARABINASE FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 | ENDO-ARABINASE, STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG
2kul:A (LEU41) to (PRO74) SOLUTION STRUCTURE OF HUMAN VACCINIA RELATED KINASE 1(VRK1) | VRK1, VACCINIA RELATED KINASE, ATP-BINDING, KINASE, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
2y5f:A (GLN30) to (THR54) FACTOR XA - CATION INHIBITOR COMPLEX | BLOOD CLOTTING, PLASMA, ZYMOGEN, HYDROLASE, BLOOD COAGULATION, HYDROXYLATION, SERINE PROTEASE, EGF-LIKE DOMAIN
2y5g:A (GLN30) to (THR54) FACTOR XA - CATION INHIBITOR COMPLEX | BLOOD CLOTTING, PLASMA, ZYMOGEN, HYDROLASE, BLOOD COAGULATION, HYDROXYLATION, SERINE PROTEASE, EGF-LIKE DOMAIN
2y5h:A (GLN30) to (THR54) FACTOR XA - CATION INHIBITOR COMPLEX | BLOOD CLOTTING, PLASMA, ZYMOGEN, HYDROLASE, BLOOD COAGULATION, HYDROXYLATION, SERINE PROTEASE, EGF-LIKE DOMAIN
2kvb:A (ALA613) to (GLY634) SOLUTION STRUCTURE OF CI-MPR DOMAIN 5 BOUND TO N-ACETYLGLUCOSAMINYL 6- PHOSPHOMETHYLMANNOSIDE | TRANSPORT, LYSOSOME, MANNOSE, RECEPTOR, SUGAR BINDING, GLYCOPROTEIN, MEMBRANE, PHOSPHOPROTEIN, TRANSMEMBRANE, DISULFIDE BOND, PROTEIN TRANSPORT
1wqv:H (GLN30) to (SER54) HUMAN FACTOR VIIA-TISSUE FACTOR COMPLEXED WITH PROPYLSULFONAMIDE-D- THR-MET-P-AMINOBENZAMIDINE | SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1wss:H (GLN30) to (SER54) HUMAN FACTOR VIIA-TISSUE FACTOR IN COMPLEX WITH PEPTIDE-MIMETIC INHIBITOR THAT HAS TWO CHARGED GROUPS IN P2 AND P4 | SERINE PROTEASE, HYDROLASE-BLOOD CLOTTING COMPLEX
1wun:H (GLN30) to (SER54) HUMAN FACTOR VIIA-TISSUE FACTOR COMPLEXED WITH ETHYLSULFONAMIDE-D-TRP-GLN-P-AMINOBENZAMIDINE | SERINE PROTEASE, HYDROLASE/BLOOD CLOTTING COMPLEX
2y7x:A (GLN30) to (THR54) THE DISCOVERY OF POTENT AND LONG-ACTING ORAL FACTOR XA INHIBITORS WITH TETRAHYDROISOQUINOLINE AND BENZAZEPINE P4 MOTIFS | BLOOD CLOTTING, HYDROLASE, SERINE PROTEASE
1wv7:H (GLN30) to (SER54) HUMAN FACTOR VIIA-TISSUE FACTOR COMPLEXED WITH ETHYLSULFONAMIDE-D-5-PROPOXY-TRP-GLN-P-AMINOBENZAMIDINE | SERINE PROTEASE, HYDROLASE/BLOOD CLOTTING COMPLEX
2y9g:A (ASN94) to (SER122) HIGH-RESOLUTION STRUCTURAL INSIGHTS ON THE SUGAR-RECOGNITION AND FUSION TAG PROPERTIES OF A VERSATILE B-TREFOIL LECTIN DOMAIN | SUGAR BINDING PROTEIN
1ki1:B (TYR1479) to (LYS1516) GUANINE NUCLEOTIDE EXCHANGE REGION OF INTERSECTIN IN COMPLEX WITH CDC42 | PROTEIN-PROTEIN COMPLEX, DH DOMAIN, PH DOMAIN, RHO GTPASE, SIGNALING PROTEIN
1ki1:D (TYR1479) to (LYS1516) GUANINE NUCLEOTIDE EXCHANGE REGION OF INTERSECTIN IN COMPLEX WITH CDC42 | PROTEIN-PROTEIN COMPLEX, DH DOMAIN, PH DOMAIN, RHO GTPASE, SIGNALING PROTEIN
2lfi:A (MET1) to (ASP51) SOLUTION NMR STRUCTURE OF A MUCBP DOMAIN (FRAGMENT 187-294) OF THE PROTEIN LBA1460 FROM LACTOBACILLUS ACIDOPHILUS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET LAR80A | NESG, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, PUTATIVE ZN BINDING, STRUCTURAL GENOMICS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, METAL BINDING PROTEIN
4nnj:A (ASN209) to (GLY241) CRYSTAL STRUCTURE OF UBA1 IN COMPLEX WITH UBIQUITIN-AMP AND THIOESTERIFIED UBIQUITIN | UBIQUITIN ACTIVATING ENZYME (E1), UBA1, UBIQUITIN, ACYLADENYLATE, UBIQUITIN THIOESTER, UBIQUITIN ACTIVATION, AMP, THIOESTERIFIED UB, PROTEIN BINDING
4nnl:B (PHE31) to (GLN79) TAX-INTERACTING PROTEIN-1 (TIP-1) PDZ DOMAIN BOUND TO F-ICAL36 (ANSRFPTSII) PEPTIDE | TAX-INTERACTING PROTEIN-1, TIP-1, PDZ, PDZ-PEPTIDE, PROTEIN BINDING
1kig:H (GLN30) to (ALA55) BOVINE FACTOR XA | GLYCOPROTEIN, SERINE PROTEASE, PLASMA, BLOOD COAGULATION, COMPLEX (PROTEASE/INHIBITOR)
4no0:D (LYS5) to (ARG39) CRYSTAL STRUCTURE OF NON-PHOSPHORYLATED FORM OF RQA_V PHOSPHOPEPTIDE BOUND TO HLA-A2 IN COMPLEX WITH LILRB1 | NONPHOSPHORYLATED PEPTIDE, PEPTIDE-MHC COMPLEX, MHC, LILRB1, POST TRANSLATIONAL MODIFICATION, PEPTIDE CONFORMATION, TUMOR IMMUNOLOGY, TUMOR ANTIGEN, NEOEPITOPE, IMMUNE SYSTEM-ANTIGEN COMPLEX
1kjh:A (VAL11) to (GLU34) SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES | RNASE H, INTEGRASE, SUBSTRATE RECOGNITION, HYDROLASE
2ya8:B (ALA437) to (ARG461) CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE NANA (TIGR4) IN COMPLEX WITH OSELTAMIVIR CARBOXYLATE | HYDROLASE, SIALIDASE
3zr6:A (GLY496) to (GLY536) STRUCTURE OF GALACTOCEREBROSIDASE FROM MOUSE IN COMPLEX WITH GALACTOSE | HYDROLASE, GALC, GLYCOSYL HYDROLASE, KRABBE DISEASE, TIM BARREL, LECTIN DOMAIN
2lnu:A (LEU108) to (ASP145) SOLUTION NMR STRUCTURE OF THE UNCHARACTERIZED PROTEIN FROM GENE LOCUS RRNAC0354 OF HALOARCULA MARISMORTUI, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HMR11 | STRUCTURAL GENOMICS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG), PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, UNKNOWN FUNCTION
2lp6:A (ARG41) to (ARG70) REFINED SOLUTION NMR STRUCTURE OF THE 50S RIBOSOMAL PROTEIN L35AE FROM PYROCOCCUS FURIOSUS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET (NESG) PFR48 | STRUCTURAL GENOMICS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG), PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, RIBOSOMAL PROTEIN
1klf:A (LYS130) to (GLU154) FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE | ADHESIN-CHAPERONE COMPLEX, MANNOSE-BOUND, CHAPERONE/ADHESIN COMPLEX COMPLEX
1klf:C (LYS130) to (GLU154) FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE | ADHESIN-CHAPERONE COMPLEX, MANNOSE-BOUND, CHAPERONE/ADHESIN COMPLEX COMPLEX
1klf:I (LYS130) to (GLU154) FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE | ADHESIN-CHAPERONE COMPLEX, MANNOSE-BOUND, CHAPERONE/ADHESIN COMPLEX COMPLEX
1klf:K (LYS130) to (GLU154) FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE | ADHESIN-CHAPERONE COMPLEX, MANNOSE-BOUND, CHAPERONE/ADHESIN COMPLEX COMPLEX
1klf:M (LYS130) to (GLU154) FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE | ADHESIN-CHAPERONE COMPLEX, MANNOSE-BOUND, CHAPERONE/ADHESIN COMPLEX COMPLEX
1klf:O (LYS130) to (GLU154) FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE | ADHESIN-CHAPERONE COMPLEX, MANNOSE-BOUND, CHAPERONE/ADHESIN COMPLEX COMPLEX
2lu3:A (GLN16) to (HIS50) SOLUTION NMR STRUCTURE OF THE APO-FORM OF THE BETA2 CARBOHYDRATE MODULE OF AMP-ACTIVATED PROTEIN KINASE | CARBOHYDRATE BINDING MODULE, GLYCOGEN BINDING, SUGAR BINDING PROTEIN
2lwy:A (VAL111) to (ASN135) SOLUTION STRUCTURE OF BACTERIAL INTEIN-LIKE DOMAIN FROM CLOSTRIDIUM THERMOCELLUM | BIL, CTHBIL4, BACTERIAL INTEIN-LIKE, HINT, UNKNOWN FUNCTION
2m2a:A (GLY96) to (HIS127) NMR SOLUTION STRUCTURE OF THE TWO DOMAIN PPIASE SLPA FROM ESCHERICHIA COLI | FKBP FOLD, ISOMERASE
5c44:K (LYS18) to (HIS40) CRYSTAL STRUCTURE OF A TRANSCRIBING RNA POLYMERASE II COMPLEX REVEALS A COMPLETE TRANSCRIPTION BUBBLE | PROTEIN-DNA COMPLEX, RNA POLYERMASE II, TRANSCRIBING COMPLEX, TRANSFERASE-DNA-RNA COMPLEX
2m5c:A (VAL8) to (VAL27) SOLUTION STRUCTURE OF THE BACILLUS CEREUS METALLO-BETA-LACTAMASE BCII | BCII, METALLO-BETA-LACTAMASE, HYDROLASE
5c4a:K (LYS18) to (HIS40) CRYSTAL STRUCTURE OF A TRANSCRIBING RNA POLYMERASE II COMPLEX REVEALS A COMPLETE TRANSCRIPTION BUBBLE | PROTEIN-DNA COMPLEX, RNA POLYMERASE II, TRANSCRIBING COMPLEX, TRANSCRIPTION BUBBLE, TRANSFERASE-RNA-DNA COMPLEX
2m9q:A (GLY197) to (THR229) NMR STRUCTURE OF AN INHIBITOR BOUND DENGUE NS3 PROTEASE | NS2B COFACTOR, COVALENT LIGAND, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3zun:I (GLN73) to (PRO103) PVHL54-213-ELOB-ELOC COMPLEX_(2S,4R)-4-HYDROXY-1-(2-(3- METHYLISOXAZOL-5-YL)ACETYL)-N-(4-NITROBENZYL)PYRROLIDINE-2- CARBOXAMIDE BOUND | TRANSCRIPTION, TUMOUR SUPRESSOR PROTEIN, PVHL E3 UBIQUITIN LIGASE
3zun:L (GLN73) to (PRO103) PVHL54-213-ELOB-ELOC COMPLEX_(2S,4R)-4-HYDROXY-1-(2-(3- METHYLISOXAZOL-5-YL)ACETYL)-N-(4-NITROBENZYL)PYRROLIDINE-2- CARBOXAMIDE BOUND | TRANSCRIPTION, TUMOUR SUPRESSOR PROTEIN, PVHL E3 UBIQUITIN LIGASE
4nt9:B (GLU56) to (ASN77) CRYSTAL STRUCTURE OF AN L,D-CARBOXYPEPTIDASE DACB FROM STREPTOCOCCUS PNEUMONIA | HYDROLASE, ZINC-BINDING
4nt9:A (GLU56) to (ASN77) CRYSTAL STRUCTURE OF AN L,D-CARBOXYPEPTIDASE DACB FROM STREPTOCOCCUS PNEUMONIA | HYDROLASE, ZINC-BINDING
4nt9:C (GLU56) to (ASN77) CRYSTAL STRUCTURE OF AN L,D-CARBOXYPEPTIDASE DACB FROM STREPTOCOCCUS PNEUMONIA | HYDROLASE, ZINC-BINDING
4nts:B (GLN42) to (ASP75) APO STRUCTURE OF THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE | PROTEIN KINASE FOLD, PHOSPHORYL TRANSFERASE, KINASE, REGULATORY SUBUNIT OF PKA, PKI, PHOSPHORYLATION, TRANSFERASE
2mki:A (CYS128) to (TRP154) SOLUTION STRUCTURE OF TANDEM RRM DOMAINS OF CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN 4 (CPEB4) IN COMPLEX WITH RNA | CPEB4, CYTOPLASMIC POLYADENYLATION, RNA RECOGNITION MOTIF (RRM), PROTEIN-RNA INTERACTION, TRANSLATIONAL REGULATION, TRANSLATION REGULATOR-RNA COMPLEX
4nw4:A (GLY86) to (VAL116) CRYSTAL STRUCTURE OF A DUF4822 FAMILY PROTEIN (EF0375) FROM ENTEROCOCCUS FAECALIS V583 AT 1.85 A RESOLUTION | TWO LIPOCAIN-LIKE DOMAINS, PF16103 FAMILY (DUF4822), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, UNKNOWN FUNCTION
1ksn:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH FXV673 | HYDROLASE
1ktg:A (VAL3) to (PRO34) CRYSTAL STRUCTURE OF A C. ELEGANS AP4A HYDROLASE BINARY COMPLEX | NUDIX, AMP, MAGNESIUM CLUSTER, HYDROLASE
2mxw:A (TYR18) to (ASP37) SOLUTION NMR STRUCTURE OF THE OCRE DOMAIN OF RBM10 | UNKNOWN FUNCTION, OCRE DOMAIN, RBM10, STRUCTURAL GENOMICS, PSI- BIOLOGY, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG
1ktz:B (ILE99) to (SER127) CRYSTAL STRUCTURE OF THE HUMAN TGF-BETA TYPE II RECEPTOR EXTRACELLULAR DOMAIN IN COMPLEX WITH TGF-BETA3 | CYTOKINE-RECEPTOR COMPLEX, CYTOKINE/CYTOKINE RECEPTOR COMPLEX
4ny2:A (ASP398) to (LEU433) STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH ACETATE ION (ACT) IN P 21 | (BETA/ALPHA)7, CARBOHYDRATE ESTERASE, HYDROLASE
2n55:A (LYS24) to (LYS54) STRUCTURE OF CONSTITUTIVELY MONOMERIC CXCL12 IN COMPLEX WITH THE CXCR4 N-TERMINUS | CXL12, CXCR4, CHEMOKINE, GPCR, SDF1, CYTOKINE-SIGNALING PROTEIN COMPLEX
4nyu:A (GLU349) to (PRO384) STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH ACETATE ION (ACT) IN C 2 2 21 | (BETA/ALPHA)7, CARBOHYDRATE ESTERASE, HYDROLASE
4nz1:A (GLU349) to (PRO384) STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH DI(N-ACETYL-D-GLUCOSAMINE) (CBS) IN P 21 | (BETA/ALPHA)7, CARBOHYDRATE ESTERASE, HYDROLASE
4nz1:B (ASP398) to (GLU432) STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH DI(N-ACETYL-D-GLUCOSAMINE) (CBS) IN P 21 | (BETA/ALPHA)7, CARBOHYDRATE ESTERASE, HYDROLASE
4nz4:B (GLU349) to (PRO384) STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH 2- (ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE (NDG) AND ZINC ION | (BETA/ALPHA)7, CARBOHYDRATE ESTERASE, HYDROLASE
1kxt:B (GLY97) to (GLY104) CAMELID VHH DOMAINS IN COMPLEX WITH PORCINE PANCREATIC ALPHA-AMYLASE | ALPHA 8 BETA 8; BETA BARREL, HYDROLASE, IMMUNE SYSTEM
1kyn:B (ALA331) to (THR354) CATHEPSIN-G | SERINE PROTEASE, HYDROLASE
5c97:B (PHE616) to (HIS653) INSULIN REGULATED AMINOPEPTIDASE | AMINOPEPTIDASE, ANTIGEN PRESENTATION, HYDROLASE, IRAP
4o0u:A (ASP132) to (PHE165) CRYSTAL STRUCTURES OF HUMAN KINASE AURORA A | PROTEIN KINASE AURORA A, PROTEIN KINASE, TRANSFERASE
5caj:A (GLY232) to (TYR255) CRYSTAL STRUCTURE OF E. COLI YAAA, A MEMBER OF THE DUF328/UPF0246 FAMILY | UNKNOWN FUNCTION
5caj:B (GLY232) to (TYR255) CRYSTAL STRUCTURE OF E. COLI YAAA, A MEMBER OF THE DUF328/UPF0246 FAMILY | UNKNOWN FUNCTION
3jqo:J (GLY223) to (ASN273) CRYSTAL STRUCTURE OF THE OUTER MEMBRANE COMPLEX OF A TYPE IV SECRETION SYSTEM | HELICAL OUTER MEMBRANE TM, OUTER MEMBRANE PROTEIN COMPLEX, TRANSPORT PROTEIN
3jqo:V (GLY223) to (ASN273) CRYSTAL STRUCTURE OF THE OUTER MEMBRANE COMPLEX OF A TYPE IV SECRETION SYSTEM | HELICAL OUTER MEMBRANE TM, OUTER MEMBRANE PROTEIN COMPLEX, TRANSPORT PROTEIN
1l4d:A (GLN576) to (THR600) CRYSTAL STRUCTURE OF MICROPLASMINOGEN-STREPTOKINASE ALPHA DOMAIN COMPLEX | STREPTOKINASE, PLASMINOGEN, PROTEIN COMPLEX, CRYSTAL STRUCTURE, HYDROLASE/HYDROLASE ACTIVATOR COMPLEX
1l4i:A (LEU131) to (ASP154) CRYSTAL STRUCTURE OF THE PERIPLASMIC CHAPERONE SFAE | PERIPLASMIC CHAPERONE, IMMUNOGLOBULIN FOLD
2ynb:B (VAL18) to (PRO39) CRYSTAL STRUCTURE OF THE MAIN PROTEASE OF CORONAVIRUS HKU4 IN COMPLEX WITH A MICHAEL ACCEPTOR SG85 | HYDROLASE, SARS, MICHAEL ACCEPTOR
2nup:B (PHE441) to (GLU463) CRYSTAL STRUCTURE OF THE HUMAN SEC23A/24A HETERODIMER, COMPLEXED WITH THE SNARE PROTEIN SEC22B | HUMAN COPII SEC23/24 COMPLEXED WITH SEC22, PROTEIN TRANSPORT
2nut:B (PHE441) to (GLU463) CRYSTAL STRUCTURE OF THE HUMAN SEC23A/24A HETERODIMER, COMPLEXED WITH THE SNARE PROTEIN SEC22B | HUMAN COPII SEC23/24 COMPLEXED WITH SEC22, PROTEIN TRANSPORT
4a0p:A (ALA632) to (ILE656) CRYSTAL STRUCTURE OF LRP6P3E3P4E4 | SIGNALING, LRP6, WNT SIGNALLING, WNT3A, DKK1, MESD
1xhg:A (THR286) to (GLN310) CRYSTAL STRUCTURE OF A 40 KDA SIGNALLING PROTEIN FROM PORCINE (SPP-40) AT 2.89A RESOLUTION | SIGNALLING PROTEIN, PORCINE, SIGNALING PROTEIN
1l8r:A (GLU187) to (CYS210) STRUCTURE OF THE RETINAL DETERMINATION PROTEIN DACHSHUND REVEALS A DNA-BINDING MOTIF | WINGED-HELIX, TRANSCRIPTION
5cek:A (LEU95) to (VAL121) PSEUDOKINASE DOMAIN OF HUMAN TRIBBLES HOMOLOG 1 | KINASE, TRANSFERASE
5cfj:A (ILE6) to (PRO46) STRUCTURAL AND FUNCTIONAL ATTRIBUTES OF MALARIA PARASITE AP4A HYDROLASE | AP4A, PURINERGIC SIGNALLING, PLASMODIUM, NUDIX HYDROLYSE, HYDROLASE
3jz1:B (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN THROMBIN MUTANT N143P IN E:NA+ FORM | SERINE PROTEASE, ACUTE PHASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, DISULFIDE BOND, GAMMA- CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, KRINGLE, PROTEASE, SECRETED, ZYMOGEN
3jz2:B (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN THROMBIN MUTANT N143P IN E* FORM | SERINE PROTEASE, ACUTE PHASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, DISULFIDE BOND, GAMMA- CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, KRINGLE, PROTEASE, SECRETED, ZYMOGEN
2yu6:A (SER48) to (ARG95) SOLUTION STRUCTURE OF THE YTH DOMAIN IN YTH DOMAIN- CONTAINING PROTEIN 2 | NMR, YTH DOMAIN, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, RNA BINDING PROTEIN
2yvx:A (TYR170) to (LYS205) CRYSTAL STRUCTURE OF MAGNESIUM TRANSPORTER MGTE | MEMBRANE PROTEIN, TRANSPORT PROTEIN
2nwn:A (PHE30) to (SER54) NEW PHARMACOPHORE FOR SERINE PROTEASE INHIBITION REVEALED BY CRYSTAL STRUCTURE OF HUMAN UROKINASE-TYPE PLASMINOGEN ACTIVATOR COMPLEXED WITH A CYCLIC PEPTIDYL INHIBITOR, UPAIN-1 | UROKINASE-TYPE PLASMINOGEN ACTIVATOR, PEPTIDYL INHIBITOR, CRYSTAL STRUCTURE, PHARMACOPHORE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, HYDROLASE
1lhd:H (GLN30) to (THR54) HUMAN ALPHA-THROMBIN COMPLEXED WITH AC-(D)PHE-PRO-BOROLYS-OH | BLOOD COAGULATION, PLASMA, CALCIUM-BINDING, GLYCOPROTEIN, DUPLICATION, VITAMIN K, ZYMOGEN, GAMMA-CARBOXYGLUTAMIC ACID, ACUTE PHASE, LIVER, HYDROLASE, SERINE PROTEASE, KRINGLE, SIGNAL, DISEASE MUTATION, COMPLEX (SERINE PROTEASE/INHIBITOR)
1lhg:H (GLN30) to (THR54) HUMAN ALPHA-THROMBIN COMPLEXED WITH AC-(D)PHE-PRO- BOROORNITHINE-OH | BLOOD COAGULATION, PLASMA, CALCIUM-BINDING, GLYCOPROTEIN, DUPLICATION, VITAMIN K, ZYMOGEN, GAMMA-CARBOXYGLUTAMIC ACID, ACUTE PHASE, LIVER, HYDROLASE, SERINE PROTEASE, KRINGLE, SIGNAL, DISEASE MUTATION, COMPLEX (SERINE PROTEASE/INHIBITOR)
1li1:A (MET118) to (TRP138) THE 1.9-A CRYSTAL STRUCTURE OF THE NONCOLLAGENOUS (NC1) DOMAIN OF HUMAN PLACENTA COLLAGEN IV SHOWS STABILIZATION VIA A NOVEL TYPE OF COVALENT MET-LYS CROSS-LINK | BASEMENT MEMBRANE, COLLAGEN IV, NC1 DOMAIN, COVALENT CROSS- LINK, PROTEIN-PROTEIN INTERACTION, STRUCTURAL PROTEIN
1li1:B (MET116) to (TRP138) THE 1.9-A CRYSTAL STRUCTURE OF THE NONCOLLAGENOUS (NC1) DOMAIN OF HUMAN PLACENTA COLLAGEN IV SHOWS STABILIZATION VIA A NOVEL TYPE OF COVALENT MET-LYS CROSS-LINK | BASEMENT MEMBRANE, COLLAGEN IV, NC1 DOMAIN, COVALENT CROSS- LINK, PROTEIN-PROTEIN INTERACTION, STRUCTURAL PROTEIN
1li1:C (ILE116) to (TRP138) THE 1.9-A CRYSTAL STRUCTURE OF THE NONCOLLAGENOUS (NC1) DOMAIN OF HUMAN PLACENTA COLLAGEN IV SHOWS STABILIZATION VIA A NOVEL TYPE OF COVALENT MET-LYS CROSS-LINK | BASEMENT MEMBRANE, COLLAGEN IV, NC1 DOMAIN, COVALENT CROSS- LINK, PROTEIN-PROTEIN INTERACTION, STRUCTURAL PROTEIN
1li1:D (MET118) to (TRP138) THE 1.9-A CRYSTAL STRUCTURE OF THE NONCOLLAGENOUS (NC1) DOMAIN OF HUMAN PLACENTA COLLAGEN IV SHOWS STABILIZATION VIA A NOVEL TYPE OF COVALENT MET-LYS CROSS-LINK | BASEMENT MEMBRANE, COLLAGEN IV, NC1 DOMAIN, COVALENT CROSS- LINK, PROTEIN-PROTEIN INTERACTION, STRUCTURAL PROTEIN
1li1:E (MET116) to (TRP138) THE 1.9-A CRYSTAL STRUCTURE OF THE NONCOLLAGENOUS (NC1) DOMAIN OF HUMAN PLACENTA COLLAGEN IV SHOWS STABILIZATION VIA A NOVEL TYPE OF COVALENT MET-LYS CROSS-LINK | BASEMENT MEMBRANE, COLLAGEN IV, NC1 DOMAIN, COVALENT CROSS- LINK, PROTEIN-PROTEIN INTERACTION, STRUCTURAL PROTEIN
1li1:F (ILE116) to (TRP138) THE 1.9-A CRYSTAL STRUCTURE OF THE NONCOLLAGENOUS (NC1) DOMAIN OF HUMAN PLACENTA COLLAGEN IV SHOWS STABILIZATION VIA A NOVEL TYPE OF COVALENT MET-LYS CROSS-LINK | BASEMENT MEMBRANE, COLLAGEN IV, NC1 DOMAIN, COVALENT CROSS- LINK, PROTEIN-PROTEIN INTERACTION, STRUCTURAL PROTEIN
2yzq:A (ARG33) to (ASP69) CRYSTAL STRUCTURE OF UNCHARACTERIZED CONSERVED PROTEIN FROM PYROCOCCUS HORIKOSHII | SHEET/HELIX/SHEET/SHEET/HELIX, STRUCTURAL GENOMICS, UNKNOWN FUNCTION, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
4a3e:B (THR1170) to (HIS1195) RNA POLYMERASE II INITIAL TRANSCRIBING COMPLEX WITH A 5NT DNA-RNA HYBRID AND SOAKED WITH AMPCPP | TRANSCRIPTION, TRANSCRIPTION INITIATION
2z0b:A (GLY7) to (PRO47) CRYSTAL STRUCTURE OF CBM20 DOMAIN OF HUMAN PUTATIVE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 5 (KIAA1434) | GDE5, KIAA1434, CBM20 DOMAIN, STARCH-BINDING, HYDROLASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
4ofo:A (LEU35) to (SER55) CRYSTAL STRUCTURE OF YNTA FROM YERSINIA PESTIS, UNLIGANDED FORM | NICKEL IMPORT, PERIPLASMIC, ABC-TYPE IMPORTER, EXTRACYTOPLASMIC NICKEL-BINDING PROTEIN, TRANSPORT PROTEIN
4ofo:C (LEU35) to (SER55) CRYSTAL STRUCTURE OF YNTA FROM YERSINIA PESTIS, UNLIGANDED FORM | NICKEL IMPORT, PERIPLASMIC, ABC-TYPE IMPORTER, EXTRACYTOPLASMIC NICKEL-BINDING PROTEIN, TRANSPORT PROTEIN
4ofo:D (LEU35) to (SER55) CRYSTAL STRUCTURE OF YNTA FROM YERSINIA PESTIS, UNLIGANDED FORM | NICKEL IMPORT, PERIPLASMIC, ABC-TYPE IMPORTER, EXTRACYTOPLASMIC NICKEL-BINDING PROTEIN, TRANSPORT PROTEIN
4a3g:B (THR1170) to (GLN1193) RNA POLYMERASE II INITIAL TRANSCRIBING COMPLEX WITH A 2NT DNA-RNA HYBRID | TRANSCRIPTION, TRANSCRIPTION INITIATION
4ogy:A (GLN405) to (THR431) CRYSTAL STRUCTURE OF FAB DX-2930 IN COMPLEX WITH HUMAN PLASMA KALLIKREIN AT 2.1 ANGSTROM RESOLUTION | FAB, ANTIBODY, KALLIKREIN, BLOOD, PLASMA, PLASMA KALLIKREIN- MEDIATED EDEMA, ACUTE HEREDITARY ANGIOEDEMA, HAE, HMWK, SERPIN C1-INHIBITOR, C1-INH, HEREDITARY ANGIOEDEMA, HAW, BRADYKININ, FLETCHER FACTOR, KININOGENIN, SERINE PROTEASE, EDEMA, HYDROLASE-ANTIBODY COMPLEX
4ogy:B (GLN405) to (THR431) CRYSTAL STRUCTURE OF FAB DX-2930 IN COMPLEX WITH HUMAN PLASMA KALLIKREIN AT 2.1 ANGSTROM RESOLUTION | FAB, ANTIBODY, KALLIKREIN, BLOOD, PLASMA, PLASMA KALLIKREIN- MEDIATED EDEMA, ACUTE HEREDITARY ANGIOEDEMA, HAE, HMWK, SERPIN C1-INHIBITOR, C1-INH, HEREDITARY ANGIOEDEMA, HAW, BRADYKININ, FLETCHER FACTOR, KININOGENIN, SERINE PROTEASE, EDEMA, HYDROLASE-ANTIBODY COMPLEX
2z3f:B (ILE3) to (SER47) CRYSTAL STRUCTURE OF SPCIA1/ASF1 COMPLEXED WITH CAC2 PEPTIDE | HISTONE CHAPERONE, NUCLEOSOME DIASSEMBLY/ASSEMBLY, CHROMATIN REGULATION, CHROMATIN REGULATOR, COILED COIL, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, WD REPEAT, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2z3f:E (ILE3) to (SER47) CRYSTAL STRUCTURE OF SPCIA1/ASF1 COMPLEXED WITH CAC2 PEPTIDE | HISTONE CHAPERONE, NUCLEOSOME DIASSEMBLY/ASSEMBLY, CHROMATIN REGULATION, CHROMATIN REGULATOR, COILED COIL, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, WD REPEAT, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2z3f:G (ILE3) to (SER47) CRYSTAL STRUCTURE OF SPCIA1/ASF1 COMPLEXED WITH CAC2 PEPTIDE | HISTONE CHAPERONE, NUCLEOSOME DIASSEMBLY/ASSEMBLY, CHROMATIN REGULATION, CHROMATIN REGULATOR, COILED COIL, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, WD REPEAT, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2z3f:H (ILE3) to (SER47) CRYSTAL STRUCTURE OF SPCIA1/ASF1 COMPLEXED WITH CAC2 PEPTIDE | HISTONE CHAPERONE, NUCLEOSOME DIASSEMBLY/ASSEMBLY, CHROMATIN REGULATION, CHROMATIN REGULATOR, COILED COIL, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, WD REPEAT, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2z3q:D (HIS11) to (ARG35) CRYSTAL STRUCTURE OF THE IL-15/IL-15RA COMPLEX | PROTEIN-PROTEIN COMPLEX, CYTOKINE/CYTOKINE RECEPTOR COMPLEX
2z3r:B (HIS11) to (ARG35) CRYSTAL STRUCTURE OF THE IL-15/IL-15RA COMPLEX | PROTEIN-PROTEIN COMPLEX, CYTOKINE-CYTOKINE RECEPTOR COMPLEX
2z3r:L (HIS11) to (ARG35) CRYSTAL STRUCTURE OF THE IL-15/IL-15RA COMPLEX | PROTEIN-PROTEIN COMPLEX, CYTOKINE-CYTOKINE RECEPTOR COMPLEX
2z43:A (GLY282) to (THR315) STRUCTURE OF A TWINNED CRYSTAL OF RADA | ARCHAEA, FILAMENT, DNA BINDING, RECOMBINATION, MOLECULAR SWITCH, RECA, RAD51, DMC1
2z43:B (GLY282) to (GLU316) STRUCTURE OF A TWINNED CRYSTAL OF RADA | ARCHAEA, FILAMENT, DNA BINDING, RECOMBINATION, MOLECULAR SWITCH, RECA, RAD51, DMC1
2z43:C (GLY282) to (THR315) STRUCTURE OF A TWINNED CRYSTAL OF RADA | ARCHAEA, FILAMENT, DNA BINDING, RECOMBINATION, MOLECULAR SWITCH, RECA, RAD51, DMC1
2z49:B (MET231) to (GLU287) CRYSTAL STRUCTURE OF HEMOLYTIC LECTIN CEL-III COMPLEXED WITH METHYL-ALPHA-D-GALACTOPYLANOSIDE | LECTIN, CEL-III, HEMOLYSIS, HEMAGGLUTINATION, PORE-FORMING, CALCIUM, MAGNESIUM, METHYL-ALPHA-D-GALACTOPYLANOSIDE, TOXIN
5cmx:H (GLN30) to (THR54) X-RAY STRUCTURE OF THE COMPLEX BETWEEN HUMAN ALPHA THROMBIN AND A DUPLEX/QUADRUPLEX 31-MER DNA APTAMER | DNA APTAMER, DUPLEX/G-QUADRUPLEX FOLD, THROMBIN, EXOSITE I, HYDROLASE
4a3j:B (THR1170) to (HIS1195) RNA POLYMERASE II INITIAL TRANSCRIBING COMPLEX WITH A 2NT DNA-RNA HYBRID AND SOAKED WITH GMPCPP | TRANSCRIPTION, TRANSCRIPTION INITIATION
1lm8:V (GLN73) to (PRO103) STRUCTURE OF A HIF-1A-PVHL-ELONGINB-ELONGINC COMPLEX | REGULATION, TUMOR SUPPRESSOR, OXYGEN SENSING, TRANSCRIPTION
1lpg:B (GLN30) to (THR54) CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 79. | PROTEIN INHIBITOR COMPLEX, BLOOD COAGULATION FACTOR, SERINE PROTEINASE, HYDROLASE
2z7f:E (MET30) to (SER54) CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN NEUTROPHIL ELASTASE WITH 1/2SLPI | SERINE PROTEASE, SERINE PROTEASE INHIBITOR, DISEASE MUTATION, GLYCOPROTEIN, HYDROLASE, ZYMOGEN, SECRETED, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3k5t:A (ARG95) to (SER129) CRYSTAL STRUCTURE OF HUMAN DIAMINE OXIDASE IN SPACE GROUP C2221 | OXIDOREDUCTASE, COPPER AMINE OXIDASE, CAO, TOPAQUINONE, TPQ, DIAMINE OXIDASE, DAO, HUMAN, GLYCOPROTEIN, HEPARIN-BINDING, METAL-BINDING, SECRETED
1xjd:A (ASP379) to (LYS412) CRYSTAL STRUCTURE OF PKC-THETA COMPLEXED WITH STAUROSPORINE AT 2A RESOLUTION | KINASE, PKC-THETA, ATP, AMP,, TRANSFERASE
2z8r:B (ASN490) to (ASP513) CRYSTAL STRUCTURE OF RHAMNOGALACTURONAN LYASE YESW AT 1.40 A RESOLUTION | BETA-PROPELLER, LYASE
3k6z:B (LYS206) to (THR232) CRYSTAL STRUCTURE OF RV3671C PROTEASE, INACTIVE FORM | SERINE PROTEASE, DISULFIDE, OXIDATIVE STRESS, BENT HELIX, HYDROLASE, PROTEASE
4a57:D (GLN64) to (ASP96) CRYSTAL STRUCTURE OF TOXOPLASMA GONDII NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3 (NTPDASE3) | HYDROLASE, NTPDASE
4a57:D (SER527) to (ASN551) CRYSTAL STRUCTURE OF TOXOPLASMA GONDII NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3 (NTPDASE3) | HYDROLASE, NTPDASE
1xkb:C (GLN30) to (THR54) FACTOR XA COMPLEXED WITH A SYNTHETIC INHIBITOR FX-2212A,(2S)-(3'- AMIDINO-3-BIPHENYLYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID | BLOOD COAGULATION FACTOR, SERINE PROTEINASE, EPIDERMAL GROWTH FACTOR LIKE DOMAIN
4a5b:A (SER527) to (ASN551) CRYSTAL STRUCTURE OF THE C258S/C268S VARIANT OF TOXOPLASMA GONDII NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1 (NTPDASE1) | HYDROLASE, NTPDASE
4a5b:B (SER527) to (ASN551) CRYSTAL STRUCTURE OF THE C258S/C268S VARIANT OF TOXOPLASMA GONDII NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1 (NTPDASE1) | HYDROLASE, NTPDASE
1lul:A (ALA22) to (TYR50) DB58, A LEGUME LECTIN FROM DOLICHOS BIFLORUS | LEGUME LECTIN, QUATERNARY STRUCTURE, PLANT HORMONE BINDING, GLYCOPROTEIN
1lul:B (ALA22) to (TYR50) DB58, A LEGUME LECTIN FROM DOLICHOS BIFLORUS | LEGUME LECTIN, QUATERNARY STRUCTURE, PLANT HORMONE BINDING, GLYCOPROTEIN
1lul:C (ALA22) to (TYR50) DB58, A LEGUME LECTIN FROM DOLICHOS BIFLORUS | LEGUME LECTIN, QUATERNARY STRUCTURE, PLANT HORMONE BINDING, GLYCOPROTEIN
1lul:D (ALA22) to (TYR50) DB58, A LEGUME LECTIN FROM DOLICHOS BIFLORUS | LEGUME LECTIN, QUATERNARY STRUCTURE, PLANT HORMONE BINDING, GLYCOPROTEIN
1lul:E (ALA22) to (TYR50) DB58, A LEGUME LECTIN FROM DOLICHOS BIFLORUS | LEGUME LECTIN, QUATERNARY STRUCTURE, PLANT HORMONE BINDING, GLYCOPROTEIN
1lul:F (ALA22) to (TYR50) DB58, A LEGUME LECTIN FROM DOLICHOS BIFLORUS | LEGUME LECTIN, QUATERNARY STRUCTURE, PLANT HORMONE BINDING, GLYCOPROTEIN
1luz:B (ARG18) to (LEU40) CRYSTAL STRUCTURE OF THE K3L PROTEIN FROM VACCINIA VIRUS (WISCONSIN STRAIN) | 5 STRANDED ANTI-PARALLEL BETA BARREL, VIRAL PROTEIN
1lvb:A (HIS20) to (ASN44) CATALYTICALLY INACTIVE TOBACCO ETCH VIRUS PROTEASE COMPLEXED WITH SUBSTRATE | BETA BARREL, PROTEIN-PEPTIDE COMPLEX, CHYMOTRYPSIN-LIKE CYSTEIN PROTEASE, VIRAL PROTEIN
1lvb:B (HIS20) to (ASN44) CATALYTICALLY INACTIVE TOBACCO ETCH VIRUS PROTEASE COMPLEXED WITH SUBSTRATE | BETA BARREL, PROTEIN-PEPTIDE COMPLEX, CHYMOTRYPSIN-LIKE CYSTEIN PROTEASE, VIRAL PROTEIN
2zag:A (PRO726) to (ASN766) CRYSTAL STRUCTURE OF THE SEMET-SUBSTITUTED SOLUBLE DOMAIN OF STT3 FROM P. FURIOSUS | MULTI-DOMAIN PROTEINS (ALPHA AND BETA), TRANSFERASE
2zag:B (PRO726) to (ASN766) CRYSTAL STRUCTURE OF THE SEMET-SUBSTITUTED SOLUBLE DOMAIN OF STT3 FROM P. FURIOSUS | MULTI-DOMAIN PROTEINS (ALPHA AND BETA), TRANSFERASE
2zai:B (PRO726) to (ASN766) CRYSTAL STRUCTURE OF THE SOLUBLE DOMAIN OF STT3 FROM P. FURIOSUS | MULTI-DOMAIN PROTEINS (ALPHA AND BETA), TRANSFERASE
2zbi:A (ASN233) to (GLY257) CRYSATL STRUCTURE OF A BACTERIAL CELL-SURFACE FLAGELLIN | FLAGELLIN, FLAGELLUM, STRUCTURAL PROTEIN
2zbi:B (ASN233) to (GLY257) CRYSATL STRUCTURE OF A BACTERIAL CELL-SURFACE FLAGELLIN | FLAGELLIN, FLAGELLUM, STRUCTURAL PROTEIN
3k7a:K (LYS18) to (HIS40) CRYSTAL STRUCTURE OF AN RNA POLYMERASE II-TFIIB COMPLEX | RNA POLYMERASE II, TFIIB, TRANSCRIPTION, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, METAL-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, ZINC- FINGER, DNA DAMAGE, DNA REPAIR, TRANSCRIPTION REGULATION
1xmw:A (LEU114) to (GLN135) CD3 EPSILON AND DELTA ECTODOMAIN FRAGMENT COMPLEX IN SINGLE- CHAIN CONSTRUCT | BETA-SHEET, C1-SET IMMUNOGLOBULIN SUPERFAMILY, H-BONDED G STRAND PAIR, SINGLE-CHAIN, SIGNALING PROTEIN
4a7i:B (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH A POTENT 2-AMINO-ETHANE SULFONAMIDE INHIBITOR | BLOOD COAGULATION FACTOR, CALCIUM- BINDING, EGF-LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, HYDROXYLATION, SERINE PROTEINASE, SERINE PROTEASE
1xn3:D (MET18) to (GLY41) CRYSTAL STRUCTURE OF BETA-SECRETASE BOUND TO A LONG INHIBITOR WITH ADDITIONAL UPSTREAM RESIDUES. | BACE, ALZHEIMER'S DISEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2zda:H (GLN30) to (THR54) EXPLORING THROMBIN S1 POCKET | BLOOD CLOTTING/HYDROLASE INHIBITORS, ACUTE PHASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, GAMMA- CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, KRINGLE, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, BLOOD CLOTTING-HYDROLASE INHIBITOR COMPLEX
3k8w:A (ASN233) to (GLY257) CRYSATL STRUCTURE OF A BACTERIAL CELL-SURFACE FLAGELLIN N20C45 | FLAGELLIN, FLAGELLUM, STRUCTURAL PROTEIN, BACTERIAL FLAGELLUM
2zdl:A (GLN30) to (SER54) EXPLORING TRYPSIN S3 POCKET | HYDROLASE INHIBITORS, DIGESTION, METAL-BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2zdm:A (GLN30) to (SER54) EXPLORING TRYPSIN S3 POCKET | HYDROLASE INHIBITORS, DIGESTION, METAL-BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2zdn:A (GLN30) to (SER54) EXPLORING TRYPSIN S3 POCKET | HYDROLASE INHIBITORS, DIGESTION, METAL-BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2zdv:H (GLN30) to (THR54) EXPLORING THROMBIN S1 POCKET | BLOOD CLOTTING/HYDROLASE INHIBITORS, ACUTE PHASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, GAMMA- CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, KRINGLE, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, BLOOD CLOTTING-HYDROLASE INHIBITOR COMPLEX
2zdy:A (GLN345) to (PRO376) INHIBITOR-BOUND STRUCTURES OF HUMAN PYRUVATE DEHYDROGENASE KINASE 4 | PDK4, KINASE, ATP-BINDING, ADP, CARBOHYDRATE METABOLISM, GLUCOSE METABOLISM, MITOCHONDRION, PHOSPHOPROTEIN, TRANSFERASE, TRANSIT PEPTIDE
4oli:A (LEU1044) to (TYR1080) THE PSEUDOKINASE/KINASE PROTEIN FROM JAK-FAMILY MEMBER TYK2 | PROTEIN KINASE, PHOSPHO-TRANSFER, TRANSFERASE
3k9x:B (GLN30) to (THR54) X-RAY CRYSTAL STRUCTURE OF HUMAN FXA IN COMPLEX WITH (S)-N-((2- METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2- (PYRROLIDIN-1-YL) ETHYL)AZEPAN-3- YLAMINO)METHYLENE)NICOTINAMIDE | SERINE PROTEASE, HYDROLASE, EPIDERMAL GROWTH FACTOR LIKE DOMAIN, BLOOD COAGULATION FACTOR, CLEAVAGE ON PAIR OF BASIC RESIDUES, EGF- LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROXYLATION, ZYMOGEN, BLOOD CLOTTING, BLOOD COAGULATION, DISULFIDE BOND, PROTEASE, SECRETED
3k9x:D (GLN30) to (THR54) X-RAY CRYSTAL STRUCTURE OF HUMAN FXA IN COMPLEX WITH (S)-N-((2- METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2- (PYRROLIDIN-1-YL) ETHYL)AZEPAN-3- YLAMINO)METHYLENE)NICOTINAMIDE | SERINE PROTEASE, HYDROLASE, EPIDERMAL GROWTH FACTOR LIKE DOMAIN, BLOOD COAGULATION FACTOR, CLEAVAGE ON PAIR OF BASIC RESIDUES, EGF- LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROXYLATION, ZYMOGEN, BLOOD CLOTTING, BLOOD COAGULATION, DISULFIDE BOND, PROTEASE, SECRETED
2zfr:H (GLN30) to (THR54) EXPLORING THROMBIN S3 POCKET | BLOOD CLOTTING/HYDROLASE INHIBITORS, ACUTE PHASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, KRINGLE, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, PROTEASE INHIBITOR, SERINE PROTEASE INHIBITOR, SULFATION, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3kab:A (PRO9) to (TRP34) STRUCTURE-GUIDED DESIGN OF ALPHA-AMINO ACID-DERIVED PIN1 INHIBITORS | SBDD, PPIASE, ISOMERASE, ROTAMASE, SMALL MOLECULE, PROLINE DIRECTED KINASE, CELL CYCLE, ONCOGENIC TRANSFORMATION, NUCLEUS, PHOSPHOPROTEIN
3kaf:A (PRO9) to (TRP34) STRUCTURE-GUIDED DESIGN OF ALPHA-AMINO ACID-DERIVED PIN1 INHIBITORS | SBDD, PPIASE, ISOMERASE, ROTAMASE, SMALL MOLECULE, PROLINE DIRECTED KINASE, CELL CYCLE, ONCOGENIC TRANSFORMATION, NUCLEUS, PHOSPHOPROTEIN
2zg1:A (LYS150) to (GLY187) CRYSTAL STRUCTURE OF TWO N-TERMINAL DOMAINS OF SIGLEC-5 IN COMPLEX WITH 6'-SIALYLLACTOSE | SIGLEC-5 INHIBITORY RECEPTOR, TWO-DOMAIN STRUCTURE, V-SET, C2-SET, IG-LIKE DOMAIN, SIALIC ACID, 6'-SIALYLLACTOSE COMPLEX, CELL ADHESION, GLYCOPROTEIN, IMMUNOGLOBULIN DOMAIN, LECTIN, MEMBRANE, POLYMORPHISM, TRANSMEMBRANE, IMMUNE SYSTEM/CARBOHYDRATE BINDING PROTEIN COMPLEX
2zg2:A (PRO151) to (GLY187) CRYSTAL STRUCTURE OF TWO N-TERMINAL DOMAINS OF NATIVE SIGLEC-5 | SIGLEC-5 INHIBITORY RECEPTOR, TWO-DOMAIN STRUCTURE, V-SET, C2-SET, IG-LIKE DOMAIN, SIALIC ACID, CELL ADHESION, GLYCOPROTEIN, IMMUNOGLOBULIN DOMAIN, LECTIN, MEMBRANE, POLYMORPHISM, TRANSMEMBRANE, IMMUNE SYSTEM/CARBOHYDRATE BINDING PROTEIN COMPLEX
2zgh:A (MET15) to (THR38) CRYSTAL STRUCTURE OF ACTIVE GRANZYME M BOUND TO ITS PRODUCT | SERINE PROTEASE, SYNTHESIZED PEPTIDE, CYTOLYSIS, GLYCOPROTEIN, HYDROLASE, PROTEASE, SECRETED, ZYMOGEN
2zgj:A (MET15) to (THR38) CRYSTAL STRUCTURE OF D86N-GZMM COMPLEXED WITH ITS OPTIMAL SYNTHESIZED SUBSTRATE | SERINE PROTEASE, SYNTHESIZED PEPTIDE, CYTOLYSIS, GLYCOPROTEIN, HYDROLASE, SECRETED, ZYMOGEN
1xr1:A (TYR38) to (GLU70) CRYSTAL STRUCTURE OF HPIM-1 KINASE IN COMPLEX WITH AMP-PNP AT 2.1 A RESOLUTION | PROTEIN KINASE FOLD, TRANSFERASE
1m52:B (THR243) to (THR272) CRYSTAL STRUCTURE OF THE C-ABL KINASE DOMAIN IN COMPLEX WITH PD173955 | KINASE, KINASE INHIBITOR, PD173955, ACTIVATION LOOP, TRANSFERASE
5cu5:A (ILE547) to (HIS587) CRYSTAL STRUCTURE OF ERAP2 WITHOUT CATALYTIC ZN(II) ATOM | HYDROLASE, AMINOPEPTIDASE, ENDOPLASMIC RETICULUM, THERMOLYSIN-LIKE CATALYTIC DOMAIN
5cu5:B (ILE547) to (HIS587) CRYSTAL STRUCTURE OF ERAP2 WITHOUT CATALYTIC ZN(II) ATOM | HYDROLASE, AMINOPEPTIDASE, ENDOPLASMIC RETICULUM, THERMOLYSIN-LIKE CATALYTIC DOMAIN
4op7:B (ASP471) to (ALA500) CRYSTAL STRUCTURE OF P DOMAIN FROM NOROVIRUS STRAIN NSW0514 IN COMPLEX WITH HBGA TYPE B (TRIGLYCAN) | NOROVIRUS, VIRAL CAPSID PROTEIN, HISTO BLOOD GROUP ANTIGEN (HBGA), PROTRUDING DOMAIN, VIRAL PROTEIN
2zkj:A (GLN345) to (PRO376) CRYSTAL STRUCTURE OF HUMAN PDK4-ADP COMPLEX | PROTEIN-NUCLEOTIDE COMPLEX, HOMODIMER, GHKL SUPERFAMILY, CARBOHYDRATE METABOLISM, GLUCOSE METABOLISM, KINASE, MITOCHONDRION, PHOSPHOPROTEIN, TRANSFERASE, TRANSIT PEPTIDE
2zkj:B (GLN345) to (PRO376) CRYSTAL STRUCTURE OF HUMAN PDK4-ADP COMPLEX | PROTEIN-NUCLEOTIDE COMPLEX, HOMODIMER, GHKL SUPERFAMILY, CARBOHYDRATE METABOLISM, GLUCOSE METABOLISM, KINASE, MITOCHONDRION, PHOSPHOPROTEIN, TRANSFERASE, TRANSIT PEPTIDE
2zks:A (MET15) to (ALA39) STRUCTURAL INSIGHTS INTO THE PROTEOLYTIC MACHINERY OF APOPTOSIS- INDUCING GRANZYME M | SERINE PROTEASE, GRANZYME, CYTOLYSIS, GLYCOPROTEIN, HYDROLASE, SECRETED, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4opx:A (GLN301) to (GLN326) STRUCTURE OF HUMAN PARP-1 BOUND TO A DNA DOUBLE STRAND BREAK IN COMPLEX WITH (2R)-5-FLUORO-2-METHYL-2,3-DIHYDRO-1-BENZOFURAN-7- CARBOXAMIDE | ZINC FINGER, DNA BINDING, PARP, POLYMERASE, DNA REPAIR, POLY(ADP- RIBOSYL)ATION, TRANSFERASE-DNA-TRANSFERASE INHIBITOR COMPLEX
4opx:D (GLN301) to (GLN326) STRUCTURE OF HUMAN PARP-1 BOUND TO A DNA DOUBLE STRAND BREAK IN COMPLEX WITH (2R)-5-FLUORO-2-METHYL-2,3-DIHYDRO-1-BENZOFURAN-7- CARBOXAMIDE | ZINC FINGER, DNA BINDING, PARP, POLYMERASE, DNA REPAIR, POLY(ADP- RIBOSYL)ATION, TRANSFERASE-DNA-TRANSFERASE INHIBITOR COMPLEX
4oqb:A (GLN301) to (GLN326) STRUCTURE OF HUMAN PARP-1 BOUND TO A DNA DOUBLE STRAND BREAK IN COMPLEX WITH (2Z)-2-{4-[2-(MORPHOLIN-4-YL)ETHOXY]BENZYLIDENE}-3-OXO- 2,3-DIHYDRO-1-BENZOFURAN-7-CARBOXAMIDE | ZINC FINGER, DNA BINDING, PARP, POLYMERASE, DNA REPAIR, POLY(ADP- RIBOSYL)ATION, TRANSFERASE-DNA-TRANSFERASE INHIBITOR COMPLEX
4oqb:D (GLN301) to (GLN326) STRUCTURE OF HUMAN PARP-1 BOUND TO A DNA DOUBLE STRAND BREAK IN COMPLEX WITH (2Z)-2-{4-[2-(MORPHOLIN-4-YL)ETHOXY]BENZYLIDENE}-3-OXO- 2,3-DIHYDRO-1-BENZOFURAN-7-CARBOXAMIDE | ZINC FINGER, DNA BINDING, PARP, POLYMERASE, DNA REPAIR, POLY(ADP- RIBOSYL)ATION, TRANSFERASE-DNA-TRANSFERASE INHIBITOR COMPLEX
1xuf:A (GLN30) to (SER54) TRYPSIN-BABIM-ZN+2, PH 8.2 | COMPLEX, TRYPSIN-ZN+2-SMALL MOLECULE LIGAND, DESIGNED SMALL MOLECULE LIGAND WITH NANOMOLAR AFFINITY, SERINE PROTEASE
5cxf:B (VAL558) to (GLU596) CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF GLYCOPROTEIN B FROM HUMAN CYTOMEGALOVIRUS | TYPE III VIRAL FUSOGEN, GLYCOPROTEIN, CYTOMEGALOVIRUS, GB, POSTFUSION FORM, VIRAL PROTEIN
1m7x:B (GLY695) to (GLU728) THE X-RAY CRYSTALLOGRAPHIC STRUCTURE OF BRANCHING ENZYME | ALPHA/BETA BARREL, BETA SANDWICH, TRANSFERASE
3kg6:A (GLU1768) to (HIS1805) DEHYDRATASE DOMAIN FROM CURF MODULE OF CURACIN POLYKETIDE SYNTHASE | POLYKETIDE SYNTHASE, DOUBLE HOTDOG FOLD, DEHYDRATASE, LYASE
3kg6:B (GLU1768) to (HIS1805) DEHYDRATASE DOMAIN FROM CURF MODULE OF CURACIN POLYKETIDE SYNTHASE | POLYKETIDE SYNTHASE, DOUBLE HOTDOG FOLD, DEHYDRATASE, LYASE
3kg6:D (GLU1768) to (HIS1805) DEHYDRATASE DOMAIN FROM CURF MODULE OF CURACIN POLYKETIDE SYNTHASE | POLYKETIDE SYNTHASE, DOUBLE HOTDOG FOLD, DEHYDRATASE, LYASE
5cyu:A (GLN187) to (ASP209) STRUCTURE OF THE SOLUBLE DOMAIN OF ECCB1 FROM THE MYCOBACTERIUM SMEGMATIS ESX-1 SECRETION SYSTEM. | MEMBRANE PROTEIN, VIRULENCE, PROTEIN SECRETION, MYCOBACTERIA, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC
5cyy:A (TRP611) to (ASN630) STRUCTURE OF THE C-TERMINAL DOMAINS OF DIPZ FROM MYCOBACTERIUM TUBERCULOSIS | THIOREDOXIN, CARBOHYDRATE BINDING MODULE, REDOX, STRUCTURAL GENOMICS, PSI-BIOLOGY, MYCOBACTERIUM TUBERCULOSIS STRUCTURAL PROTEOMICS PROJECT, XMTB, MEMBRANE PROTEIN
5cyy:B (ARG610) to (ASN630) STRUCTURE OF THE C-TERMINAL DOMAINS OF DIPZ FROM MYCOBACTERIUM TUBERCULOSIS | THIOREDOXIN, CARBOHYDRATE BINDING MODULE, REDOX, STRUCTURAL GENOMICS, PSI-BIOLOGY, MYCOBACTERIUM TUBERCULOSIS STRUCTURAL PROTEOMICS PROJECT, XMTB, MEMBRANE PROTEIN
4ab1:A (PRO23) to (GLY52) RECOMBINANT HUMAN CARBOXYLESTERASE 1 FROM WHOLE CABBAGE LOOPERS | HYDROLASE, WHOLE INSECT EXPRESSION SYSTEMS
2zpr:B (GLN15) to (SER37) CRYSTAL STRUCTURE OF ANIONIC TRYPSIN ISOFORM 2 FROM CHUM SALMON | SERINE PROTEINASE, TRYPSIN, HYDROLASE, PROTEASE, SERINE PROTEASE
2zq1:A (GLN30) to (SER54) EXPLORING TRYPSIN S3 POCKET | HYDROLASE INHIBITORS, DIGESTION, HYDROLASE, METAL-BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1xxd:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF THE FXIA CATALYTIC DOMAIN IN COMPLEX WITH MUTATED ECOTIN | FXIA; CATALYTIC DOMAIN; SERINE PROTEIN; ECOTIN, BLOOD CLOTTING/HYDROLASE INHIBITOR COMPLEX
2zqv:A (PRO9) to (TRP34) CRYSTAL STRUCTURE OF A MUTANT PIN1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE | PIN1 MUTANT F25A, CELL CYCLE, ISOMERASE, NUCLEUS, PHOSPHOPROTEIN, ROTAMASE
4ou3:A (MET543) to (ILE581) CRYSTAL STRUCTURE OF PORCINE AMINOPEPTIDASE N COMPLEXED WITH CNGRCG TUMOR-HOMING PEPTIDE | ZINC-AMINOPEPTIDASE, HYDROLASE-PROTEIN BINDING COMPLEX
4abh:A (GLN30) to (SER54) FRAGMENTS BOUND TO BOVINE TRYPSIN FOR THE SAMPL CHALLENGE | HYDROLASE, FRAGMENT SCREENING, MODELLING
4oui:A (GLU349) to (PRO384) STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH TRIACETYLCHITOTRIOSE (CTO) | (BETA/ALPHA)7, CARBOHYDRATE ESTERASE, HYDROLASE
4oui:B (ASP398) to (GLU432) STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH TRIACETYLCHITOTRIOSE (CTO) | (BETA/ALPHA)7, CARBOHYDRATE ESTERASE, HYDROLASE
1may:A (GLN30) to (SER54) BETA-TRYPSIN PHOSPHONATE INHIBITED | HYDROLASE, SERINE PROTEASE, DIGESTION, PANCREAS, ZYMOGEN, HYDROLASE (SERINE PROTEASE)
1mbq:A (GLN30) to (SER54) ANIONIC TRYPSIN FROM PACIFIC CHUM SALMON | PSYCHROPHILIC ENZYMES, PROTEINASE-CATALYZED PEPTIDE COUPLING, HYDROLASE
1mc0:A (ILE422) to (PRO453) REGULATORY SEGMENT OF MOUSE 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 2A, CONTAINING THE GAF A AND GAF B DOMAINS | GAF DOMAIN, 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE, 3',5'- GUANOSINE MONOPHOSPHATE, HYDROLASE
1mct:A (GLN30) to (SER54) THE REFINED 1.6 ANGSTROMS RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PORCINE BETA-TRYPSIN AND MCTI-A, A TRYPSIN INHIBITOR OF SQUASH FAMILY | COMPLEX(PROTEINASE/INHIBITOR)
3kio:C (VAL52) to (VAL75) MOUSE RNASE H2 COMPLEX | RIBONUCLEASE, AICARDI-GOUTIERES SYNDROME, RNASE H2, PROTEIN COMPLEX, AUTOIMMUNE DISEASE, ENDONUCLEASE, HYDROLASE, METAL-BINDING, NUCLEASE, NUCLEUS, PHOSPHOPROTEIN, ACETYLATION
2zuc:A (GLY282) to (GLU316) CRYSTAL STRUCTURE OF LEFT-HANDED RADA FILAMENT | ARCHAEA, FILAMENT, LEFT-HANDED, DNA BINDING, RECOMBINATION, MOLECULAR SWITCH, RECA, RAD51, DMC1, ATP-BINDING, DNA DAMAGE, DNA RECOMBINATION, DNA-BINDING, NUCLEOTIDE-BINDING
2zuc:B (GLY282) to (GLU316) CRYSTAL STRUCTURE OF LEFT-HANDED RADA FILAMENT | ARCHAEA, FILAMENT, LEFT-HANDED, DNA BINDING, RECOMBINATION, MOLECULAR SWITCH, RECA, RAD51, DMC1, ATP-BINDING, DNA DAMAGE, DNA RECOMBINATION, DNA-BINDING, NUCLEOTIDE-BINDING
2zud:A (GLY282) to (GLU316) CRYSTAL STRUCTURE OF LEFT-HANDED RADA FILAMENT | ARCHAEA, LEFT-HANDED HELICAL FILAMENT, DNA-BINDING, RECOMBINATION, RECA, RAD51, DMC1, ATP-BINDING, DNA DAMAGE, DNA RECOMBINATION, NUCLEOTIDE-BINDING
4owj:F (VAL380) to (THR400) CRYSTAL STRUCTURE OF THE VIBRIO VULNIFICUS HEMOLYSIN/CYTOLYSIN BETA- TREFOIL LECTIN | LECTIN, PORE-FORMING TOXIN, BETA-TREFOIL, R-TYPE LECTIN, TOXIN
4owj:G (VAL380) to (THR400) CRYSTAL STRUCTURE OF THE VIBRIO VULNIFICUS HEMOLYSIN/CYTOLYSIN BETA- TREFOIL LECTIN | LECTIN, PORE-FORMING TOXIN, BETA-TREFOIL, R-TYPE LECTIN, TOXIN
4owl:B (GLN418) to (LEU441) CRYSTAL STRUCTURE OF THE VIBRIO VULNIFICUS HEMOLYSIN/CYTOLYSIN BETA- TREFOIL LECTIN WITH N-ACETYL-D-LACTOSAMINE BOUND | LECTIN, PORE-FORMING TOXIN, BETA-TREFOIL, R-TYPE LECTIN, TOXIN
4owl:C (VAL380) to (THR400) CRYSTAL STRUCTURE OF THE VIBRIO VULNIFICUS HEMOLYSIN/CYTOLYSIN BETA- TREFOIL LECTIN WITH N-ACETYL-D-LACTOSAMINE BOUND | LECTIN, PORE-FORMING TOXIN, BETA-TREFOIL, R-TYPE LECTIN, TOXIN
4owl:E (VAL380) to (THR400) CRYSTAL STRUCTURE OF THE VIBRIO VULNIFICUS HEMOLYSIN/CYTOLYSIN BETA- TREFOIL LECTIN WITH N-ACETYL-D-LACTOSAMINE BOUND | LECTIN, PORE-FORMING TOXIN, BETA-TREFOIL, R-TYPE LECTIN, TOXIN
4acq:A (PHE89) to (ASP134) ALPHA-2 MACROGLOBULIN | HYDROLASE INHIBITOR, PROTEINASE INHIBITOR, IRREVERSIBLE PROTEINASE INHIBITOR, CONFORMATIONAL CHANGE, BLOOD PLASMA INHIBITOR
4acq:B (PHE89) to (ASP134) ALPHA-2 MACROGLOBULIN | HYDROLASE INHIBITOR, PROTEINASE INHIBITOR, IRREVERSIBLE PROTEINASE INHIBITOR, CONFORMATIONAL CHANGE, BLOOD PLASMA INHIBITOR
4acq:D (PHE89) to (ASP134) ALPHA-2 MACROGLOBULIN | HYDROLASE INHIBITOR, PROTEINASE INHIBITOR, IRREVERSIBLE PROTEINASE INHIBITOR, CONFORMATIONAL CHANGE, BLOOD PLASMA INHIBITOR
1y1v:B (THR1170) to (ILE1194) REFINED RNA POLYMERASE II-TFIIS COMPLEX | RNA POLYMERASE II, TFIIS, TRANSCRIPTION, ELONGATION, TRANSFERASE/TRANSCRIPTION COMPLEX
1y1v:K (LYS18) to (HIS40) REFINED RNA POLYMERASE II-TFIIS COMPLEX | RNA POLYMERASE II, TFIIS, TRANSCRIPTION, ELONGATION, TRANSFERASE/TRANSCRIPTION COMPLEX
3kl6:A (GLN30) to (THR54) DISCOVERY OF TETRAHYDROPYRIMIDIN-2(1H)-ONE DERIVATIVE TAK-442: A POTENT, SELECTIVE AND ORALLY ACTIVE FACTOR XA INHIBITOR | COAGULATION FACTOR XA, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISULFIDE BOND, EGF-LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, HYDROXYLATION, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN
3kl9:A (ARG100) to (GLY141) CRYSTAL STRUCTURE OF PEPA FROM STREPTOCOCCUS PNEUMONIAE | GLUTAMYL AMINOPEPTIDASE, PEPA, TETRAHEDRAL AMINOPEPTIDASE, SUBSTRATE SPECIFICITY, METALLOPEPTIDASE M42, AMINOPEPTIDASE, HYDROLASE
3kl9:B (ARG100) to (GLY141) CRYSTAL STRUCTURE OF PEPA FROM STREPTOCOCCUS PNEUMONIAE | GLUTAMYL AMINOPEPTIDASE, PEPA, TETRAHEDRAL AMINOPEPTIDASE, SUBSTRATE SPECIFICITY, METALLOPEPTIDASE M42, AMINOPEPTIDASE, HYDROLASE
3kl9:C (ARG100) to (GLY141) CRYSTAL STRUCTURE OF PEPA FROM STREPTOCOCCUS PNEUMONIAE | GLUTAMYL AMINOPEPTIDASE, PEPA, TETRAHEDRAL AMINOPEPTIDASE, SUBSTRATE SPECIFICITY, METALLOPEPTIDASE M42, AMINOPEPTIDASE, HYDROLASE
3kl9:D (ARG100) to (GLY141) CRYSTAL STRUCTURE OF PEPA FROM STREPTOCOCCUS PNEUMONIAE | GLUTAMYL AMINOPEPTIDASE, PEPA, TETRAHEDRAL AMINOPEPTIDASE, SUBSTRATE SPECIFICITY, METALLOPEPTIDASE M42, AMINOPEPTIDASE, HYDROLASE
3kl9:E (ARG100) to (GLY141) CRYSTAL STRUCTURE OF PEPA FROM STREPTOCOCCUS PNEUMONIAE | GLUTAMYL AMINOPEPTIDASE, PEPA, TETRAHEDRAL AMINOPEPTIDASE, SUBSTRATE SPECIFICITY, METALLOPEPTIDASE M42, AMINOPEPTIDASE, HYDROLASE
3kl9:F (PHE101) to (GLY141) CRYSTAL STRUCTURE OF PEPA FROM STREPTOCOCCUS PNEUMONIAE | GLUTAMYL AMINOPEPTIDASE, PEPA, TETRAHEDRAL AMINOPEPTIDASE, SUBSTRATE SPECIFICITY, METALLOPEPTIDASE M42, AMINOPEPTIDASE, HYDROLASE
3kl9:G (ARG100) to (GLY141) CRYSTAL STRUCTURE OF PEPA FROM STREPTOCOCCUS PNEUMONIAE | GLUTAMYL AMINOPEPTIDASE, PEPA, TETRAHEDRAL AMINOPEPTIDASE, SUBSTRATE SPECIFICITY, METALLOPEPTIDASE M42, AMINOPEPTIDASE, HYDROLASE
3kl9:H (ARG100) to (GLY141) CRYSTAL STRUCTURE OF PEPA FROM STREPTOCOCCUS PNEUMONIAE | GLUTAMYL AMINOPEPTIDASE, PEPA, TETRAHEDRAL AMINOPEPTIDASE, SUBSTRATE SPECIFICITY, METALLOPEPTIDASE M42, AMINOPEPTIDASE, HYDROLASE
3kl9:I (PHE101) to (GLY141) CRYSTAL STRUCTURE OF PEPA FROM STREPTOCOCCUS PNEUMONIAE | GLUTAMYL AMINOPEPTIDASE, PEPA, TETRAHEDRAL AMINOPEPTIDASE, SUBSTRATE SPECIFICITY, METALLOPEPTIDASE M42, AMINOPEPTIDASE, HYDROLASE
3kl9:J (ARG100) to (GLY141) CRYSTAL STRUCTURE OF PEPA FROM STREPTOCOCCUS PNEUMONIAE | GLUTAMYL AMINOPEPTIDASE, PEPA, TETRAHEDRAL AMINOPEPTIDASE, SUBSTRATE SPECIFICITY, METALLOPEPTIDASE M42, AMINOPEPTIDASE, HYDROLASE
3kl9:K (ARG100) to (GLY141) CRYSTAL STRUCTURE OF PEPA FROM STREPTOCOCCUS PNEUMONIAE | GLUTAMYL AMINOPEPTIDASE, PEPA, TETRAHEDRAL AMINOPEPTIDASE, SUBSTRATE SPECIFICITY, METALLOPEPTIDASE M42, AMINOPEPTIDASE, HYDROLASE
3kl9:L (ARG100) to (GLY141) CRYSTAL STRUCTURE OF PEPA FROM STREPTOCOCCUS PNEUMONIAE | GLUTAMYL AMINOPEPTIDASE, PEPA, TETRAHEDRAL AMINOPEPTIDASE, SUBSTRATE SPECIFICITY, METALLOPEPTIDASE M42, AMINOPEPTIDASE, HYDROLASE
2zux:A (ASN490) to (TYR514) CRYSTAL STRUCTURE OF RHAMNOGALACTURONAN LYASE YESW COMPLEXED WITH RHAMNOSE | BETA-PROPELLER, LYASE, RHAMNOSE COMPLEX
2zux:B (ASN490) to (TYR514) CRYSTAL STRUCTURE OF RHAMNOGALACTURONAN LYASE YESW COMPLEXED WITH RHAMNOSE | BETA-PROPELLER, LYASE, RHAMNOSE COMPLEX
2zw9:B (LYS551) to (HIS592) CRYSTAL STRUCTURE OF TRNA WYBUTOSINE SYNTHESIZING ENZYME TYW4 | TRANSFERASE
1y3y:A (GLN30) to (SER54) TRYPSIN INHIBITOR COMPLEX | TRYPSIN, INHIBITOR COMPLEX, BARREL, 6 STRANDED BETA-SHEET, HYDROLASE
4afu:A (TYR14) to (THR42) HUMAN CHYMASE - FYNOMER COMPLEX | HYDROLASE-DE NOVO PROTEIN COMPLEX, INHIBITOR, SERINE PROTEASE
4afu:B (TYR14) to (THR42) HUMAN CHYMASE - FYNOMER COMPLEX | HYDROLASE-DE NOVO PROTEIN COMPLEX, INHIBITOR, SERINE PROTEASE
4ag1:A (TYR14) to (THR42) HUMAN CHYMASE - FYNOMER COMPLEX | HYDROLASE-DE NOVO PROTEIN COMPLEX, INHIBITOR, SERINE PROTEASE
4ag2:A (TYR14) to (THR42) HUMAN CHYMASE - FYNOMER COMPLEX | HYDROLASE-DE NOVO PROTEIN COMPLEX, INHIBITOR, SERINE PROTEASE
4ag2:B (TYR14) to (THR42) HUMAN CHYMASE - FYNOMER COMPLEX | HYDROLASE-DE NOVO PROTEIN COMPLEX, INHIBITOR, SERINE PROTEASE
1y59:T (GLN30) to (SER54) DIANHYDROSUGAR-BASED BENZAMIDINE, FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN MUTANT | HYDROLASE, SERINE PROTEASE, SERINE PROTEINASE
1y5b:T (GLN30) to (ALA55) DIANHYDROSUGAR-BASED BENZAMIDINE, FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN MUTANT | HYDROLASE, SERINE PROTEASE, SERINE PROTEINASE
1mkx:K (GLN30) to (THR54) THE CO-CRYSTAL STRUCTURE OF UNLIGANDED BOVINE ALPHA- THROMBIN AND PRETHROMBIN-2: MOVEMENT OF THE YPPW SEGMENT AND ACTIVE SITE RESIDUES UPON LIGAND BINDING | COMPLEX (BLOOD COAGULATION/PROENZYME), THROMBIN, PRETHROMBIN-2, PLASMA, SERINE PROTEASE
3kmv:C (GLN43) to (ASN74) CRYSTAL STRUCTURE OF CBM42A FROM CLOSTRIDIUM THERMOCELLUM | PROTEIN:CARBOYDRATE INTERACTIONS, CARBOHYDRATE-BINDING MODULE, BETA- TREFOIL FOLD, CBM42, SUGAR BINDING PROTEIN
3kmx:B (MET79) to (GLY102) STRUCTURE OF BACE BOUND TO SCH346572 | ALZHEIMER'S, BACE1, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
2zye:B (VAL111) to (GLU134) STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH POTENT INHIBITOR KNI-272 DETERMINED BY NEUTRON CRYSTALLOGRAPHY | HIV-1 PROTEASE, ACID PROTEASE, HOMODIMER, HYDROLASE, MULTIFUNCTIONAL ENZYME, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1mp8:A (ARG421) to (CYS456) CRYSTAL STRUCTURE OF FOCAL ADHESION KINASE (FAK) | TYROSINE PROTEIN KINASE, TRANSFERASE
2zzu:H (GLN30) to (SER54) HUMAN FACTOR VIIA-TISSUE FACTOR COMPLEXED WITH ETHYLSULFONAMIDE-D-5- (3-CARBOXYBENZYLOXY)-TRP-GLN-P-AMINOBENZAMIDINE | SERINE PROTEASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, EGF-LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, HYDROXYLATION, PROTEASE, ZYMOGEN, LIPOPROTEIN, MEMBRANE, PALMITATE, TRANSMEMBRANE, HYDROLASE-BLOOD CLOTTING COMPLEX, SECRETED
1y8f:A (GLN566) to (HIS605) SOLUTION STRUCTURE OF THE MUNC13-1 C1-DOMAIN | CYSTEINE-RICH DOMAIN, C1-DOMAIN, ZINC-BINDING DOMAIN, ENDOCYTOSIS/EXOCYTOSIS,SIGNALING PROTEIN COMPLEX
1y8p:A (GLN339) to (PRO370) CRYSTAL STRUCTURE OF THE PDK3-L2 COMPLEX | PYRUVATE DEHYDROGENASE KINASE 3, LIPOYL-BEARING DOMAIN, PROTEIN- PROTEIN COMPLEX, TRANSFERASE
3a0f:A (HIS451) to (LYS476) THE CRYSTAL STRUCTURE OF GEOTRICHUM SP. M128 XYLOGLUCANASE | BETA-PROPELLER, HYDROLASE
1ya4:A (PRO23) to (GLY52) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 IN COMPLEX WITH TAMOXIFEN | HYDROLASE DOMAIN, TAMOXIFEN COMPLEX, HYDROLASE
1ya4:B (PRO23) to (GLY52) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 IN COMPLEX WITH TAMOXIFEN | HYDROLASE DOMAIN, TAMOXIFEN COMPLEX, HYDROLASE
1ya4:C (PRO23) to (GLY52) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 IN COMPLEX WITH TAMOXIFEN | HYDROLASE DOMAIN, TAMOXIFEN COMPLEX, HYDROLASE
1ya8:A (PRO23) to (GLY52) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH CLEAVAGE PRODUCTS OF MEVASTATIN | HYDROLASE, CARBOXYLESTERASE, MEVASTATIN
1ya8:B (PRO23) to (GLY52) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH CLEAVAGE PRODUCTS OF MEVASTATIN | HYDROLASE, CARBOXYLESTERASE, MEVASTATIN
1ya8:C (PRO23) to (GLY52) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH CLEAVAGE PRODUCTS OF MEVASTATIN | HYDROLASE, CARBOXYLESTERASE, MEVASTATIN
1mro:F (ARG174) to (GLY202) METHYL-COENZYME M REDUCTASE | BIOLOGICAL METHANOGENESIS, NI-ENZYME, OXIDOREDUCTASE, METHANOGENESIS
1yah:A (PRO23) to (GLY52) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE COMPLEXED TO ETYL ACETATE; A FATTY ACID ETHYL ESTER ANALOGUE | HYDROLASE, CARBOXYLESTERASE, ETHYL ACETATE, FATTY ACID ACYL ESTER
1yah:B (PRO23) to (GLY52) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE COMPLEXED TO ETYL ACETATE; A FATTY ACID ETHYL ESTER ANALOGUE | HYDROLASE, CARBOXYLESTERASE, ETHYL ACETATE, FATTY ACID ACYL ESTER
1yah:C (PRO23) to (GLY52) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE COMPLEXED TO ETYL ACETATE; A FATTY ACID ETHYL ESTER ANALOGUE | HYDROLASE, CARBOXYLESTERASE, ETHYL ACETATE, FATTY ACID ACYL ESTER
3kqe:A (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH THE INHIBITOR 3-METHYL-1-(3-(5- OXO-4,5- DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-6-(2'- (PYRROLIDIN-1-YLMETHYL) BIPHENYL-4-YL)-5,6-DIHYDRO-1H- PYRAZOLO[3,4-C]PYRIDIN-7(4H)-ONE | GLYCOPROTEIN, SERINE PROTEASE, PLASMA, BLOOD COAGULATION FACTOR, PROTEIN INHIBITOR COMPLEX, CALCIUM- BINDING, BLOOD COAGULATION, CALCIUM, PROTEASE, SECRETED, EGF-LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, HYDROLASE
1yaj:A (PRO23) to (GLY52) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH BENZIL | HYDROLASE, CARBOXYLESTERASE, BENZIL, INHIBITION
1yaj:D (PRO23) to (GLY52) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH BENZIL | HYDROLASE, CARBOXYLESTERASE, BENZIL, INHIBITION
1yaj:G (PRO23) to (GLY52) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH BENZIL | HYDROLASE, CARBOXYLESTERASE, BENZIL, INHIBITION
1yaj:H (PRO23) to (GLY52) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH BENZIL | HYDROLASE, CARBOXYLESTERASE, BENZIL, INHIBITION
1msk:A (GLY1162) to (HIS1184) METHIONINE SYNTHASE (ACTIVATION DOMAIN) | METHYLTRANSFERASE, TRANSFERASE, METHIONINE BIOSYNTHESIS, VITAMIN B12
4p8q:A (PHE616) to (HIS653) CRYSTAL STRUCTURE OF HUMAN INSULIN REGULATED AMINOPEPTIDASE WITH ALANINE IN ACTIVE SITE | AMINOPEPTIDASE, METALLOPEPTIDASE, HYDROLASE
1mtv:A (GLN30) to (SER54) FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN | HYDROLASE, SERINE PROTEASE
1mtw:A (GLN30) to (SER54) FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN | HYDROLASE, SERINE PROTEASE
1mui:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH LOPINAVIR. | HYDROLASE
3ksc:C (ALA420) to (LEU446) CRYSTAL STRUCTURE OF PEA PROLEGUMIN, AN 11S SEED GLOBULIN FROM PISUM SATIVUM L. | PEA PROLEGUMIN, 11S SEED STORAGE PROTEIN, PISUM SATIVUM L., SEED STORAGE PROTEIN, STORAGE PROTEIN, PLANT PROTEIN
3ksk:A (GLY47) to (ASN73) CRYSTAL STRUCTURE OF SINGLE CHAIN PVUII | SINGLE CHAIN RESTRICTION ENDONUCLEASE, DNA-BINDING PROTEIN, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, NUCLEASE, RESTRICTION SYSTEM
3ksk:A (GLY207) to (ASN233) CRYSTAL STRUCTURE OF SINGLE CHAIN PVUII | SINGLE CHAIN RESTRICTION ENDONUCLEASE, DNA-BINDING PROTEIN, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, NUCLEASE, RESTRICTION SYSTEM
4ajy:V (GLN73) to (PRO103) VON HIPPEL-LINDAU PROTEIN-ELONGINB-ELONGINC COMPLEX, BOUND TO HIF1- ALPHA PEPTIDE | E3 UBIQUITIN LIGASE, TRANSCRIPTION FACTOR, HYPOXIC SIGNALING, TRANSCRIPTION
1mx1:A (PRO1023) to (GLY1052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH TACRINE | ESTERASE, HYDROLASE, ESTERASE INHIBITOR
1mx1:B (PRO2023) to (GLY2052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH TACRINE | ESTERASE, HYDROLASE, ESTERASE INHIBITOR
1mx1:C (PRO3023) to (GLY3052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH TACRINE | ESTERASE, HYDROLASE, ESTERASE INHIBITOR
1mx1:D (PRO4023) to (GLY4052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH TACRINE | ESTERASE, HYDROLASE, ESTERASE INHIBITOR
1mx1:F (PRO6023) to (GLY6052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEX WITH TACRINE | ESTERASE, HYDROLASE, ESTERASE INHIBITOR
1mx5:A (PRO1023) to (GLY1052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH HOMATROPINE, A COCAINE ANALOGUE | ESTERASE, HYDROLASE, COCAINE
1mx5:B (PRO2023) to (GLY2052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH HOMATROPINE, A COCAINE ANALOGUE | ESTERASE, HYDROLASE, COCAINE
1mx5:C (PRO3023) to (GLY3052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH HOMATROPINE, A COCAINE ANALOGUE | ESTERASE, HYDROLASE, COCAINE
1mx5:D (PRO4023) to (GLY4052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH HOMATROPINE, A COCAINE ANALOGUE | ESTERASE, HYDROLASE, COCAINE
1mx5:E (PRO5023) to (GLY5052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH HOMATROPINE, A COCAINE ANALOGUE | ESTERASE, HYDROLASE, COCAINE
1mx5:F (PRO6023) to (GLY6052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH HOMATROPINE, A COCAINE ANALOGUE | ESTERASE, HYDROLASE, COCAINE
1mx9:A (PRO1023) to (GLY1052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH NALOXONE METHIODIDE, A HEROIN ANALOGUE | ESTERASE, HYDROLASE, HEROIN
1mx9:B (PRO2023) to (GLY2052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH NALOXONE METHIODIDE, A HEROIN ANALOGUE | ESTERASE, HYDROLASE, HEROIN
1mx9:D (PRO4023) to (GLY4052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH NALOXONE METHIODIDE, A HEROIN ANALOGUE | ESTERASE, HYDROLASE, HEROIN
1mx9:E (PRO5023) to (GLY5052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH NALOXONE METHIODIDE, A HEROIN ANALOGUE | ESTERASE, HYDROLASE, HEROIN
1mx9:F (PRO6023) to (GLY6052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH NALOXONE METHIODIDE, A HEROIN ANALOGUE | ESTERASE, HYDROLASE, HEROIN
1mx9:H (PRO2023) to (GLY2052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH NALOXONE METHIODIDE, A HEROIN ANALOGUE | ESTERASE, HYDROLASE, HEROIN
1mx9:I (PRO3023) to (GLY3052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH NALOXONE METHIODIDE, A HEROIN ANALOGUE | ESTERASE, HYDROLASE, HEROIN
1mx9:J (PRO4023) to (GLY4052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH NALOXONE METHIODIDE, A HEROIN ANALOGUE | ESTERASE, HYDROLASE, HEROIN
1mx9:K (PRO5023) to (GLY5052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE IN COMPLEXED WITH NALOXONE METHIODIDE, A HEROIN ANALOGUE | ESTERASE, HYDROLASE, HEROIN
4pdo:A (CYS612) to (LEU648) STRUCTURE OF EPHRIN TYPE-A RECEPTOR 2 | EPHA2, TRANSFERASE
5da9:A (THR1167) to (ASP1202) ATP-GAMMA-S BOUND RAD50 FROM CHAETOMIUM THERMOPHILUM IN COMPLEX WITH THE RAD50-BINDING DOMAIN OF MRE11 | ATPASE, ATPYS BOUND, HYDROLASE
5da9:B (THR1167) to (ASP1202) ATP-GAMMA-S BOUND RAD50 FROM CHAETOMIUM THERMOPHILUM IN COMPLEX WITH THE RAD50-BINDING DOMAIN OF MRE11 | ATPASE, ATPYS BOUND, HYDROLASE
3a7x:A (GLN33) to (SER55) CRYSTAL STRUCTURE OF TRYPSIN COMPLEXED WITH (E)-2-(4- CARBAMIMIDOYLBENZYLIDENEAMINOOXY)ACETIC ACID (SOAKING 45SECONDS) | IN-CRYSTAL CHEMICAL LIGATION, DIGESTION, DISULFIDE BOND, HYDROLASE, METAL-BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN
3a85:A (GLN33) to (SER55) CRYSTAL STRUCTURE OF TRYPSIN COMPLEXED WITH (E)-2-(4- CARBAMIMIDOYLBENZYLIDENEAMINOOXY)ACETIC ACID (SOAKING 15 SECONDS) | IN-CRYSTAL CHEMICAL LIGATION, DISULFIDE BOND, HYDROLASE, METAL- BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN
3a86:A (GLN33) to (SER55) CRYSTAL STRUCTURE OF TRYPSIN COMPLEXED WITH (E)-2-(4- CARBAMIMIDOYLBENZYLIDENEAMINOOXY)ACETIC ACID (SOAKING 30 SECONDS) | IN-CRYSTAL CHEMICAL LIGATION, DISULFIDE BOND, HYDROLASE, METAL- BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN
3kvn:X (PHE489) to (TYR550) CRYSTAL STRUCTURE OF THE FULL-LENGTH AUTOTRANSPORTER ESTA FROM PSEUDOMONAS AERUGINOSA | BETA BARREL, ALPHA-BETA-ALPHA MOTIF, CELL MEMBRANE, CELL OUTER MEMBRANE, HYDROLASE, MEMBRANE, TRANSMEMBRANE
3kvn:A (PHE489) to (TYR550) CRYSTAL STRUCTURE OF THE FULL-LENGTH AUTOTRANSPORTER ESTA FROM PSEUDOMONAS AERUGINOSA | BETA BARREL, ALPHA-BETA-ALPHA MOTIF, CELL MEMBRANE, CELL OUTER MEMBRANE, HYDROLASE, MEMBRANE, TRANSMEMBRANE
1mza:A (MET30) to (THR54) CRYSTAL STRUCTURE OF HUMAN PRO-GRANZYME K | GRANZYME, APOPTOSIS, SERINE PROTEASE, S1 FAMILY, HYDROLASE
3kw3:B (GLN256) to (ARG276) CRYSTAL STRUCTURE OF ALANINE RACEMASE FROM BARTONELLA HENSELAE WITH COVALENTLY BOUND PYRIDOXAL PHOSPHATE | NIAID, SSGCID, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, IODIDE SOAK, ALANINE RACEMASE, LLP, CAT-SCRATCH DISEASE, ISOMERASE
1mzu:B (PHE94) to (LYS124) CRYSTAL STRUCTURE OF THE PHOTOACTIVE YELLOW PROTEIN DOMAIN FROM THE SENSOR HISTIDINE KINASE PPR FROM RHODOSPIRILLUM CENTENUM | PHOTOACTIVE YELLOW PROTEIN, PAS, PYP, PPR, SIGNALING PROTEIN
3aae:A (GLY85) to (ASP107) CRYSTAL STRUCTURE OF ACTIN CAPPING PROTEIN IN COMPLEX WITH CARMIL FRAGMENT | ACTIN CAPPING PROTEIN, BARBED END REGULATION, CARMIL FAMILY PROTEIN, CONFORMATIONAL CHANGE, CELL MOTILITY, ACTIN CAPPING, ACTIN-BINDING, CYTOSKELETON, ISOPEPTIDE BOND, LEUCINE-RICH REPEAT, PROTEIN BINDING
3aae:C (GLY85) to (ASP107) CRYSTAL STRUCTURE OF ACTIN CAPPING PROTEIN IN COMPLEX WITH CARMIL FRAGMENT | ACTIN CAPPING PROTEIN, BARBED END REGULATION, CARMIL FAMILY PROTEIN, CONFORMATIONAL CHANGE, CELL MOTILITY, ACTIN CAPPING, ACTIN-BINDING, CYTOSKELETON, ISOPEPTIDE BOND, LEUCINE-RICH REPEAT, PROTEIN BINDING
3aae:E (GLY85) to (ASP107) CRYSTAL STRUCTURE OF ACTIN CAPPING PROTEIN IN COMPLEX WITH CARMIL FRAGMENT | ACTIN CAPPING PROTEIN, BARBED END REGULATION, CARMIL FAMILY PROTEIN, CONFORMATIONAL CHANGE, CELL MOTILITY, ACTIN CAPPING, ACTIN-BINDING, CYTOSKELETON, ISOPEPTIDE BOND, LEUCINE-RICH REPEAT, PROTEIN BINDING
3aae:G (GLY85) to (ASP107) CRYSTAL STRUCTURE OF ACTIN CAPPING PROTEIN IN COMPLEX WITH CARMIL FRAGMENT | ACTIN CAPPING PROTEIN, BARBED END REGULATION, CARMIL FAMILY PROTEIN, CONFORMATIONAL CHANGE, CELL MOTILITY, ACTIN CAPPING, ACTIN-BINDING, CYTOSKELETON, ISOPEPTIDE BOND, LEUCINE-RICH REPEAT, PROTEIN BINDING
3aae:I (GLY85) to (ASP107) CRYSTAL STRUCTURE OF ACTIN CAPPING PROTEIN IN COMPLEX WITH CARMIL FRAGMENT | ACTIN CAPPING PROTEIN, BARBED END REGULATION, CARMIL FAMILY PROTEIN, CONFORMATIONAL CHANGE, CELL MOTILITY, ACTIN CAPPING, ACTIN-BINDING, CYTOSKELETON, ISOPEPTIDE BOND, LEUCINE-RICH REPEAT, PROTEIN BINDING
3ab0:C (ILE3) to (TYR32) CRYSTAL STRUCTURE OF COMPLEX OF THE BACILLUS ANTHRACIS MAJOR SPORE SURFACE PROTEIN BCLA WITH SCFV ANTIBODY FRAGMENT | EXOSPORIUM, ANTHRAX, TBCLA, SCFV COMPLEX, IMMUNE SYSTEM
1ymz:A (GLY6) to (TRP30) CC45, AN ARTIFICIAL WW DOMAIN DESIGNED USING STATISTICAL COUPLING ANALYSIS | ARTIFICIAL PROTEIN, COMPUTATIONAL DESIGN, UNKNOWN FUNCTION
3kyr:B (GLY13) to (ALA43) BACE-1 IN COMPLEX WITH A NORSTATINE TYPE INHIBITOR | BACE, BETA-SECRETASE, MEMAPSIN-2, ASPARTYL PROTEASE, INHIBITOR, NORSTATINE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ypj:H (GLN30) to (THR54) THROMBIN INHIBITOR COMPLEX | THROMBIN, INHIBITOR COMPLEX, BARREL, 6 STRANDED BETA-SHEET, BLOOD CLOTTING-HYDROLASE INHIBITOR COMPLEX
1ypq:B (GLY205) to (GLY232) HUMAN OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR LOX-1 DIOXANE COMPLEX | OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR, LOX-1, CTLD, C- TYPE LECTIN LIKE DOMAIN, NK CELL RECEPTOR, IMMUNE SYSTEM
5dgo:A (VAL492) to (PHE522) CRYSTAL STRUCTURE OF CELL DIVISION CYCLE PROTEIN 45 (CDC45) | DNA REPLICATION, CMG HELICASE SUBUNIT, RECJ FOLD, CELL CYCLE
4pix:A (ARG57) to (SER84) UNLIGANDED CYSTEINE DIOXYGENASE C93A VARIANT AT PH 6.2 | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, CYTOSOL, OXIDOREDUCTASE
4piy:A (ARG57) to (SER84) HOMOCYSTEINE BOUND CYSTEINE DIOXYGENASE C93A VARIANT AT PH 6.2 | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
4piz:A (ARG57) to (SER84) HOMOCYSTEINE-BOUND CYSTEINE DIOXYGENASE AT PH 6.2 | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
3l2k:B (LEU268) to (ASP298) STRUCTURE OF PHENAZINE ANTIBIOTIC BIOSYNTHESIS PROTEIN WITH SUBSTRATE | PHENAZINE, ANTIBIOTIC, BIOSYNTHETIC PROTEIN, PDC
5dh3:A (VAL26) to (PRO59) CRYSTAL STRUCTURE OF MST2 IN COMPLEX WITH XMU-MP-1 | MST2, MST1, HIPPO PATHWAY, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3aee:A (GLU176) to (ARG208) CRYSTAL STRUCTURE OF PORCINE HEART MITOCHONDRIAL COMPLEX II BOUND WITH ATPENIN A5 | RESPIRATORY COMPLEX II, INHIBITORS, ELECTRON TRANSPORT, IRON, IRON- SULFUR, METAL-BINDING, MITOCHONDRION, MITOCHONDRION INNER MEMBRANE, OXIDOREDUCTASE, TRANSIT PEPTIDE, TRANSPORT, TRICARBOXYLIC ACID CYCLE, HEME, TRANSMEMBRANE, FAD-BINDING PROTEIN, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
5dif:B (GLY109) to (PRO142) CRYSTAL STRUCTURE OF CPEB4 NES PEPTIDE IN COMPLEX WITH CRM1-RAN-RANBP1 | PEPTIDES, HEAT REPEAT, NUCLEAR EXPORT SIGNAL, EXPORTIN-1, NUCLEAR TRANSPORT, TRANSPORT PROTEIN
5dif:B (GLU143) to (ALA165) CRYSTAL STRUCTURE OF CPEB4 NES PEPTIDE IN COMPLEX WITH CRM1-RAN-RANBP1 | PEPTIDES, HEAT REPEAT, NUCLEAR EXPORT SIGNAL, EXPORTIN-1, NUCLEAR TRANSPORT, TRANSPORT PROTEIN
4pjy:A (ARG57) to (SER84) AZIDE BOUND CYSTEINE DIOXYGENASE AT PH 6.2 | CUPIN FOLD, CATALYZES OXIDATION, CYSTEINE TO CYSTEINE SULFINATE, C93- Y157 CROSSLINK, CYTOSOL, OXIDOREDUCTASE
3l58:A (MET79) to (GLY102) STRUCTURE OF BACE BOUND TO SCH589432 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3l58:B (MET79) to (GLY102) STRUCTURE OF BACE BOUND TO SCH589432 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
1ywj:A (MET16) to (THR38) STRUCTURE OF THE FBP11WW1 DOMAIN | WW DOMAIN, CLASS II, PROLINE-RICH PEPTIDES, PROTEIN-PROTEIN INTERACTIONS, STRUCTURAL PROTEIN
5dkx:A (ASP759) to (TRP784) CRYSTAL STRUCTURE OF GLUCOSIDASE II ALPHA SUBUNIT (TRIS-BOUND FROM) | ENDOPLASMIC RETICULUM, GLYCOSIDE HYDROLASE, GLYCOSYLATION, HYDROLASE
5dky:A (ASP759) to (TRP784) CRYSTAL STRUCTURE OF GLUCOSIDASE II ALPHA SUBUNIT (DNJ-BOUND FROM) | ENDOPLASMIC RETICULUM, GLYCOSIDE HYDROLASE, GLYCOSYLATION, HYDROLASE
1yzy:A (THR367) to (GLY396) CRYSTAL STRUCTURE OF HAEMOPHILUS INFLUENZAE PROTEIN HI1011, PFAM DUF1537 | PUTATIVE TRNA SYNTHASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, UNKNOWN FUNCTION
3ai0:A (SER457) to (GLU478) CRYSTAL STRUCTURE OF BETA-GLUCOSIDASE FROM TERMITE NEOTERMES KOSHUNENSIS IN COMPLEX WITH PARA-NITROPHENYL-BETA-D-GLUCOPYRANOSIDE | CELLULASES, GLYCOSYL HYDROLASE, MANGANESE ENHANCEMENT, HYDROLASE
4amh:A (PHE17) to (ALA59) INFLUENCE OF CIRCULAR PERMUTATION ON THE FOLDING PATHWAY OF A PDZ DOMAIN | PERMUTATION, PROTEIN FOLDING, STRUCTURAL PROTEIN
4amh:B (PHE17) to (ALA59) INFLUENCE OF CIRCULAR PERMUTATION ON THE FOLDING PATHWAY OF A PDZ DOMAIN | PERMUTATION, PROTEIN FOLDING, STRUCTURAL PROTEIN
4amv:C (GLY209) to (GLU235) E.COLI GLUCOSAMINE-6P SYNTHASE IN COMPLEX WITH FRUCTOSE-6P | TRANSFERASE, AMMONIA CHANNELING, GLUCOSAMINE 6- PHOSPHATE SYNTHASE, N TERMINAL NUCLEOPHILE, GLUTAMINE AMIDOTRANSFERASE
1z71:A (GLN30) to (THR54) THROMBIN AND P2 PYRIDINE N-OXIDE INHIBITOR COMPLEX STRUCTURE | THROMBIN INHIBITOR COMPLEX, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4psp:A (ARG406) to (VAL431) CRYSTAL STRUCTURE OF GH29 FAMILY ALPHA-L-FUCOSIDASE FROM FUSARIUM GRAMINEARUM IN THE OPEN FORM | FUCOSIDASE, GH29, GLYCOSIDE HYDROLASE, TIM BARREL, N-GLYCOSYLATION, HYDROLASE
4psp:B (ARG406) to (VAL431) CRYSTAL STRUCTURE OF GH29 FAMILY ALPHA-L-FUCOSIDASE FROM FUSARIUM GRAMINEARUM IN THE OPEN FORM | FUCOSIDASE, GH29, GLYCOSIDE HYDROLASE, TIM BARREL, N-GLYCOSYLATION, HYDROLASE
4psq:B (ASP72) to (ASP108) CRYSTAL STRUCTURE OF RETINOL-BINDING PROTEIN 4 (RBP4) IN COMPLEX WITH A NON-RETINOID LIGAND | RETINOL BINDING, DISEASE MUTATION, SECRETED, SENSORY TRANSDUCTION, VISION, VITAMIN A, TRANSPORT PROTEIN
3ldo:A (GLY28) to (TYR65) CRYSTAL STRUCTURE OF HUMAN GRP78 (70KDA HEAT SHOCK PROTEIN 5 / BIP) ATPASE DOMAIN IN COMPLEX WITH AMPPNP | GRP78, HSP70, HSC70, CHAPERONE, HEAT SHOCK, PROTEIN FOLDING, ATP- BINDING, ADENOSINE, NUCLEOSIDE, NUCLEOTIDE-BINDING, STRESS RESPONSE, SMALL MOLECULE INHIBITOR, SELECTIVITY, ENDOPLASMIC RETICULUM, PHOSPHOPROTEIN
3lem:A (TRP231) to (TYR264) CRYSTAL STRUCTURE OF FRUCTOSYLTRANSFERASE (D191A) FROM A. JAPONICUS IN COMPLEX WITH NYSTOSE | PROTEIN-OLIGOSACCHARIDE COMPLEX, FIVE BLADED BETA-PROPELLER FOLD, HYDROLASE
3lf7:A (TRP231) to (TYR264) CRYSTAL STRUCTURE OF FRUCTOSYLTRANSFERASE (WILD-TYPE) FROM A. JAPONICUS | FIVE BLADED BETA-PROPELLER FOLD, HYDROLASE
3lfi:A (TRP231) to (LEU265) CRYSTAL STRUCTURE OF FRUCTOSYLTRANSFERASE (WILD-TYPE) FROM A. JAPONICUS IN COMPLEX WITH GLUCOSE | PROTEIN-OLIGOSACCHARIDE COMPLEX, FIVE BLADED BETA-PROPELLER FOLD, HYDROLASE
3alq:S (ASP81) to (CYS104) CRYSTAL STRUCTURE OF TNF-TNFR2 COMPLEX | LIGAND-RECEPTOR COMPLEX, CYTOKINE, CYTOKINE-CYTOKINE RECEPTOR COMPLEX
3alq:T (ASP81) to (LEU106) CRYSTAL STRUCTURE OF TNF-TNFR2 COMPLEX | LIGAND-RECEPTOR COMPLEX, CYTOKINE, CYTOKINE-CYTOKINE RECEPTOR COMPLEX
3alt:A (LEU2) to (HIS21) CRYSTAL STRUCTURE OF CEL-IV COMPLEXED WITH MELIBIOSE | CEL-IV, C-TYPE LECTIN, MELIBIOSE, SUGAR BINDING PROTEIN
3alu:B (CYS1) to (HIS21) CRYSTAL STRUCTURE OF CEL-IV COMPLEXED WITH RAFFINOSE | CEL-IV, C-TYPE LECTIN, RAFFINOSE, SUGAR BINDING PROTEIN
3lgi:B (ASN60) to (THR93) STRUCTURE OF THE PROTEASE DOMAIN OF DEGS (DEGS-DELTAPDZ) AT 1.65 A | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgi:C (VAL59) to (ASN94) STRUCTURE OF THE PROTEASE DOMAIN OF DEGS (DEGS-DELTAPDZ) AT 1.65 A | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgt:A (GLN103) to (ASN133) Y162A/H198P DOUBLE MUTANT OF DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgv:A (VAL61) to (THR93) H198P MUTANT OF THE DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgv:B (ILE104) to (ASN133) H198P MUTANT OF THE DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgv:C (VAL61) to (THR93) H198P MUTANT OF THE DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgv:D (VAL154) to (ASP193) H198P MUTANT OF THE DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgv:E (VAL61) to (THR93) H198P MUTANT OF THE DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgv:E (VAL154) to (ASP193) H198P MUTANT OF THE DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgv:F (VAL61) to (THR93) H198P MUTANT OF THE DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgv:G (VAL59) to (THR93) H198P MUTANT OF THE DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgv:H (VAL154) to (ASP193) H198P MUTANT OF THE DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgv:I (VAL59) to (THR93) H198P MUTANT OF THE DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgv:I (VAL154) to (ASP193) H198P MUTANT OF THE DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lgy:A (GLY202) to (ILE236) R178A MUTANT OF THE DEGS-DELTAPDZ PROTEASE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lh1:A (GLN103) to (ASN133) Q191A MUTANT OF THE DEGS-DELTAPDZ | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lh3:C (VAL59) to (THR93) DFP MODIFIED DEGS DELTA PDZ | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lh3:D (ASN60) to (THR93) DFP MODIFIED DEGS DELTA PDZ | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lh3:E (VAL59) to (THR93) DFP MODIFIED DEGS DELTA PDZ | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lh3:F (VAL61) to (THR93) DFP MODIFIED DEGS DELTA PDZ | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lh3:G (VAL59) to (THR93) DFP MODIFIED DEGS DELTA PDZ | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lh3:H (VAL58) to (THR93) DFP MODIFIED DEGS DELTA PDZ | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lh3:I (VAL59) to (THR93) DFP MODIFIED DEGS DELTA PDZ | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
3lh3:I (VAL154) to (ASP193) DFP MODIFIED DEGS DELTA PDZ | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, SERINE PROTEASE
4aoq:C (GLN38) to (SER60) CATIONIC TRYPSIN IN COMPLEX WITH MUTATED SPINACIA OLERACEA TRYPSIN INHIBITOR III (SOTI-III) (F14A) | HYDROLASE-INHIBITOR COMPLEX, MINIPROTEIN SCAFFOLD, KNOTTINS, SERINE PROTEASE INHIBITOR
3lih:A (TRP231) to (LEU265) CRYSTAL STRUCTURE OF FRUCTOSYLTRANSFERASE (D191A) FROM A. JAPONICUS IN COMPLEX WITH RAFFINOSE | PROTEIN-OLIGOSACCHARIDE COMPLEX, FIVE BLADED BETA-PROPELLER FOLD, HYDROLASE
1zbv:A (THR286) to (GLN310) CRYSTAL STRUCTURE OF THE GOAT SIGNALLING PROTEIN (SPG-40) COMPLEXED WITH A DESIGNED PEPTIDE TRP-PRO-TRP AT 3.2A RESOLUTION | SIGNALLING PROTEIN, DESIGNED LIGAND, TRP-PRO-TRP
4px8:A (GLY62) to (ILE85) STRUCTURE OF P. VULGARIS HIGB TOXIN | BACTERIAL TOXINS, BIOFILMS, CELL METABOLISM, ENERGY METABOLISM, MICROBIAL PATHOGENESIS, STRESS RESPONSE, STRINGENT RESPONSE, TRANSLATION CONTROL, TOXIN, MICROBIAL RNASE FOLD, RIBOSOME-DEPENDENT MRNA INTERFERASE, HOST INHIBITION OF GROWTH A, MRNA, AND RIBOSOME
4pyg:A (GLY472) to (VAL504) TRANSGLUTAMINASE2 COMPLEXED WITH GTP | PROTEIN-GTP COMPLEX, TRANSGLUTAMINASE FOLD, CROSSLINKING, GTP BINDING, NO MODIFICATION, TRANSFERASE
1zhr:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH BENZAMIDINE (S434A-T475A-C482S-K437A MUTANT) | FACTOR XI; BENZAMIDINE, HYDROLASE, BLOOD CLOTTING
4pz6:B (ASN247) to (PHE286) PCE1 GUANYLYLTRANSFERASE BOUND TO SER2/SER5 PHOSPHORYLATED RNA POL II CTD | NUCLEOTIDYL TRANSFERASE, RNA CAPPING ENZYME, RNA POLYMERASE II, SPT5, GUANYLATION, NUCLEAR, TRANSFERASE-TRANSCRIPTION COMPLEX
4pz8:A (ASN247) to (PHE286) PCE1 GUANYLYLTRANSFERASE BOUND TO SPT5 CTD | NUCLEOTIDYL TRANSFERASE, RNA CAPPING ENZYME, RNA POLYMERASE II, SPT5, GUANYLATION, NUCLEAR, TRANSFERASE-TRANSCRIPTION COMPLEX
5dvh:A (GLU19) to (SER51) STRUCTURE OF THE KUNITZ-TYPE CYSTEINE PROTEASE INHIBITOR PCPI-3 FROM POTATO | PLANT KUNITZ-FAMILY INHIBITOR, PROTEASE INHIBITOR
3llp:B (THR213) to (GLN258) 1.8 ANGSTROM HUMAN FASCIN 1 CRYSTAL STRUCTURE | BETA-TREFOIL, ACTIN BUNDLING PROTEIN, CANCER, METASTASIS, CELL MIGRATION, ACETYLATION, ACTIN-BINDING, CYTOPLASM, PHOSPHOPROTEIN, PROTEIN BINDING
3lnm:C (PHE38) to (THR56) F233W MUTANT OF THE KV2.1 PADDLE-KV1.2 CHIMERA CHANNEL | VOLTAGE-GATED POTASSIUM CHANNEL-BETA SUBUNIT COMPLEX, ACETYLATION, CYTOPLASM, ION TRANSPORT, IONIC CHANNEL, NADP, PHOSPHOPROTEIN, POTASSIUM, POTASSIUM TRANSPORT, TRANSPORT, VOLTAGE-GATED CHANNEL, GLYCOPROTEIN, LIPOPROTEIN, MEMBRANE, PALMITATE, POTASSIUM CHANNEL, TRANSMEMBRANE, MEMBRANE PROTEIN, TRANSPORT PROTEIN
1zmn:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH (R)-1-(4-(4-(HYDROXYMETHYL)-1,3, 2-DIOXABOROLAN-2-YL)PHENYL)GUANIDINE | FXI, INHIBITOR, HYDROLASE
4q3h:A (GLY165) to (GLU201) THE CRYSTAL STRUCTURE OF NHERF1 PDZ2 CXCR2 COMPLEX REVEALED BY THE NHERF1 CXCR2 CHIMERIC PROTEIN | SCAFFOLD PROTEIN, DIMERIZATION, NEUTROPHIL CHEMOTAXIS, IMMUNE SYSTEM
4q46:B (GLN450) to (LYS483) THE SECOND STRUCTURE OF INFLUENZA B PB2 CAP-BINDING DOMAIN COMPLEX WITH GDP | CAP BINDING, VIRAL PROTEIN
1zom:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH A PEPTIDOMIMETIC INHIBITOR | FXIA, INHIBITOR, HYDROLASE
3lpr:A (ILE29) to (ALA55) STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1zpb:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH 4-METHYL-PENTANOIC ACID {1-[4- GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYLCARBAMOYL]-2-METHYL- PROPYL}-AMIDE | FXI, INHIBITOR, HYDROLASE
1zpc:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH 2-[2-(3-CHLORO-PHENYL)-2-HYDROXY- ACETYLAMINO]-N-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYL]- 3-METHYL-BUTYRAMIDE | FXI, INHIBITOR, HYDROLASE
1zqx:A (GLY290) to (LEU311) DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF KCL (150 MILLIMOLAR) | DNA-DIRECTED DNA POLYMERASE, DNA REPLICATION, DNA REPAIR, NUCLEOTIDYLTRANSFERASE
1zr0:A (GLN30) to (SER54) CRYSTAL STRUCTURE OF KUNITZ DOMAIN 1 OF TISSUE FACTOR PATHWAY INHIBITOR-2 WITH BOVINE TRYPSIN | SERINE PROTEASE; COMPLEX OF SERINE PROTEASE/INHIBITOR; KUNITZ TYPE INHIBITOR, HYDROLASE/BLOOD CLOTTING COMPLEX
1zsj:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH N-(7-CARBAMIMIDOYL-NAPHTHALEN-1- YL)-3-HYDROXY-2-METHYL-BENZAMIDE | FXIA, INHIBITORS, HYDROLASE
1zsk:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH 6-CARBAMIMIDOYL-4-(3-HYDROXY-2- METHYL-BENZOYLAMINO)-NAPHTHALENE-2-CARBOXYLIC ACID METHYL ESTER | FXIA, INHIBITORS, HYDROLASE
3apn:A (VAL74) to (ASP120) CRYSTAL STRUCTURE OF THE HUMAN WILD-TYPE PAD4 PROTEIN | ALPHA/BETA-PROPELLER, IMMUNOGLOBULIN-LIKE, ARGININE CITRULLINATION, HYDROLASE, PROTEIN-ARGININE DEIMINASE, POST-TRANSLATIONAL MODIFICATION, CALCIUM BINDING, HISTONE BINDING, BENZOYL-L-ARGININE AMIDE BINDING, NUCLEUS
1ztj:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH 2-(5-BENZYLAMINO-2- METHYLSULFANYL-6-OXO-6H-PYRIMIDIN-1-YL)-N-[4-GUANIDINO-1- (THIAZOLE-2-CARBONYL)-BUTYL]-ACETAMIDE | FXIA, INHIBITORS, HYDROLASE
1ztk:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH 2-(5-AMINO-6-OXO-2-M-TOLYL-6H- PYRIMIDIN-1-YL)-N-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)- BUTYL]-ACETAMIDE | FXIA, INHIBITORS, HYDROLASE
1zu8:A (THR286) to (GLN310) CRYSTAL STRUCTURE OF THE GOAT SIGNALLING PROTEIN WITH A BOUND TRISACCHARIDE REVEALS THAT TRP78 REDUCES THE CARBOHYDRATE BINDING SITE TO HALF | SIGNALLING PROTEIN,COMPLEX TRISACCHARIDE,CRYSTAL STRUCTURE, SIGNALING PROTEIN
3aqo:A (LYS202) to (GLU230) STRUCTURE AND FUNCTION OF A MEMBRANE COMPONENT SECDF THAT ENHANCES PROTEIN EXPORT | PERIPLASMIC DOMAIN, SECDF, SEC, TRANSLOCON, CELL MEMBRANE, MEMBRANE, PROTEIN TRANSPORT, TRANSLOCATION, TRANSMEMBRANE, TRANSPORT, MEMBRANE PROTEIN
3aqo:B (LYS202) to (GLU230) STRUCTURE AND FUNCTION OF A MEMBRANE COMPONENT SECDF THAT ENHANCES PROTEIN EXPORT | PERIPLASMIC DOMAIN, SECDF, SEC, TRANSLOCON, CELL MEMBRANE, MEMBRANE, PROTEIN TRANSPORT, TRANSLOCATION, TRANSMEMBRANE, TRANSPORT, MEMBRANE PROTEIN
3aqo:C (LYS202) to (GLU230) STRUCTURE AND FUNCTION OF A MEMBRANE COMPONENT SECDF THAT ENHANCES PROTEIN EXPORT | PERIPLASMIC DOMAIN, SECDF, SEC, TRANSLOCON, CELL MEMBRANE, MEMBRANE, PROTEIN TRANSPORT, TRANSLOCATION, TRANSMEMBRANE, TRANSPORT, MEMBRANE PROTEIN
3aqo:D (LYS202) to (GLU230) STRUCTURE AND FUNCTION OF A MEMBRANE COMPONENT SECDF THAT ENHANCES PROTEIN EXPORT | PERIPLASMIC DOMAIN, SECDF, SEC, TRANSLOCON, CELL MEMBRANE, MEMBRANE, PROTEIN TRANSPORT, TRANSLOCATION, TRANSMEMBRANE, TRANSPORT, MEMBRANE PROTEIN
4aw5:A (TYR90) to (LEU125) COMPLEX OF THE EPHB4 KINASE DOMAIN WITH AN OXINDOLE INHIBITOR | TRANSFERASE
1zxe:D (PHE599) to (ARG631) CRYSTAL STRUCTURE OF EIF2ALPHA PROTEIN KINASE GCN2: D835N INACTIVATING MUTANT IN APO FORM | TRANSLATION REGULATOR, PROTEIN KINASE, SIGNAL TRANSDUCTION, AMINO- ACID STARVATION, STARVATION STRESS RESPONSE, EIF2ALPHA KINASE, TRANSFERASE
4q68:A (ILE198) to (HIS227) CRYSTAL STRUCTURE OF A N-ACETYLMURAMOYL-L-ALANINE AMIDASE (BACUNI_02947) FROM BACTEROIDES UNIFORMIS ATCC 8492 AT 1.07 A RESOLUTION | PF07313 FAMILY PROTEIN, DUF 1460, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
4q6j:B (SER16) to (PRO50) CRYSTAL STRUCTURE OF EAL DOMAIN PROTEIN FROM LISTERIA MONOCYTOGENES EGD-E | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, TIM BARREL, ALPHA-BETAFOLD, UNKNOWN FUNCTION
4ax9:H (GLN30) to (THR54) HUMAN THROMBIN COMPLEXED WITH NAPSAGATRAN, RO0466240 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, HYDROLASE HYDROLASE INHIBITOR COMPLEX
5e5l:C (LEU125) to (GLY153) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 1 AT 1.89 ANGSTROM | PEPTIDOGLYCAN SYNTHESIS ENZYME, CELL WALL ENZYME, TRANSFERASE
5e5l:D (LEU125) to (GLY153) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 1 AT 1.89 ANGSTROM | PEPTIDOGLYCAN SYNTHESIS ENZYME, CELL WALL ENZYME, TRANSFERASE
3lvk:A (ASP198) to (GLU227) CRYSTAL STRUCTURE OF E.COLI ISCS-TUSA COMPLEX (FORM 2) | PROTEIN-PROTEIN COMPLEX, STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, TRANSFERASE, TRNA THIOLATION, SULFUR TRANSFER
3asq:B (LEU473) to (VAL499) CRYSTAL STRUCTURE OF P DOMAIN FROM NOROVIRUS FUNABASHI258 STAIN IN THE COMPLEX WITH H-ANTIGEN | PROTEIN-SUGAR COMPLEX, HISTO-BLOOD GROUP ANTIGEN, CAPSID PROTEIN, LECTIN-LIKE PROTEIN, VIRAL PROTEIN
3ast:B (LEU473) to (VAL499) CRYSTAL STRUCTURE OF P DOMAIN Q389N MUTANT FROM NOROVIRUS FUNABASHI258 STAIN IN THE COMPLEX WITH LEWIS-B | PROTEIN-SUGAR COMPLEX, HISTO-BLOOD GROUP ANTIGEN, CAPSID PROTEIN, LECTIN-LIKE PROTEIN, VIRAL PROTEIN
4q80:A (MET30) to (SER54) NEUTROPHIL SERINE PROTEASE 4 (PRSS57) WITH VAL-LEU-LYS- CHLOROMETHYLKETONE (VLK-CMK) | TRYPSIN HOMOLOGY, PEPTIDASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4q80:B (MET30) to (SER54) NEUTROPHIL SERINE PROTEASE 4 (PRSS57) WITH VAL-LEU-LYS- CHLOROMETHYLKETONE (VLK-CMK) | TRYPSIN HOMOLOGY, PEPTIDASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3lwh:A (GLU23) to (PRO55) CRYSTAL STRUCTURE OF CREN7-DSDNA COMPLEX | PROTEIN-DNA COMPLEX, BETA-SHEET, DNA-BINDING, METHYLATION, DNA BINDING PROTEIN-DNA COMPLEX
5e70:B (THR696) to (GLU728) CRYSTAL STRUCTURE OF ECOLI BRANCHING ENZYME WITH GAMMA CYCLODEXTRIN | BRANCHING ENZYME, CYCLODEXTRIN, GLYCOGEN, STARCH, GLUCAN, TRANSFERASE
2a1e:B (VAL11) to (GLU34) HIGH RESOLUTION STRUCTURE OF HIV-1 PR WITH TS-126 | HIV PR, PEPTIDOMIMETIC INHIBITOR, STEREOISOMER, SCREENING A MIXTURE, HYDROLASE
5e8e:H (GLN335) to (THR360) CRYSTAL STRUCTURE OF THROMBIN BOUND TO AN EXOSITE 1-SPECIFIC IGA FAB | IMMUNE SYSTEM-HYDROLASE COMPLEX, IMMUNE SYSTEM, INHIBITOR
3lza:B (GLY101) to (MSE145) CRYSTAL STRUCTURE OF PUTATIVE SNOAL-LIKE POLYKETIDE CYCLASE (YP_563807.1) FROM SHEWANELLA DENITRIFICANS OS-217 AT 1.70 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
3lza:C (GLY101) to (ASP146) CRYSTAL STRUCTURE OF PUTATIVE SNOAL-LIKE POLYKETIDE CYCLASE (YP_563807.1) FROM SHEWANELLA DENITRIFICANS OS-217 AT 1.70 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
3lza:D (GLY101) to (MSE145) CRYSTAL STRUCTURE OF PUTATIVE SNOAL-LIKE POLYKETIDE CYCLASE (YP_563807.1) FROM SHEWANELLA DENITRIFICANS OS-217 AT 1.70 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
2a2q:H (GLN30) to (SER54) COMPLEX OF ACTIVE-SITE INHIBITED HUMAN COAGULATION FACTOR VIIA WITH HUMAN SOLUBLE TISSUE FACTOR IN THE PRESENCE OF CA2+, MG2+, NA+, AND ZN2+ | FACTOR VIIA, SOLUBLE TISSUE FACTOR, MG2+, CA2+, NA+, ZN2+, HYDROLASE/BLOOD CLOTTING COMPLEX
4b2g:A (TYR366) to (GLY415) CRYSTAL STRUCTURE OF AN INDOLE-3-ACETIC ACID AMIDO SYNTHASE FROM VITIS VINIFERA INVOLVED IN AUXIN HOMEOSTASIS | SIGNALING PROTEIN, IGNALING PROTEIN, ADENYLATE, AMINO ACID CONJUGATION, PLANT GROWTH
4b2g:B (TYR366) to (GLY415) CRYSTAL STRUCTURE OF AN INDOLE-3-ACETIC ACID AMIDO SYNTHASE FROM VITIS VINIFERA INVOLVED IN AUXIN HOMEOSTASIS | SIGNALING PROTEIN, IGNALING PROTEIN, ADENYLATE, AMINO ACID CONJUGATION, PLANT GROWTH
3m0c:B (LEU455) to (SER485) THE X-RAY CRYSTAL STRUCTURE OF PCSK9 IN COMPLEX WITH THE LDL RECEPTOR | PROTEIN COMPLEX, BETA PROPELLER, CHOLESTEROL CLEARANCE, PCSK9, LDLR, AUTOCATALYTIC CLEAVAGE, CHOLESTEROL METABOLISM, DISEASE MUTATION, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, LIPID METABOLISM, PHOSPHOPROTEIN, PROTEASE, SECRETED, SERINE PROTEASE, STEROID METABOLISM, ZYMOGEN, COATED PIT, EGF-LIKE DOMAIN, ENDOCYTOSIS, HOST- VIRUS INTERACTION, LDL, LIPID TRANSPORT, MEMBRANE, RECEPTOR, TRANSMEMBRANE, TRANSPORT, PROTEIN BINDING
2a5z:C (ASP48) to (THR73) CRYSTAL STRUCTURE OF PROTEIN OF UNKNOWN FUNCTION SO2946 FROM SHEWANELLA ONEIDENSIS MR-1 | SHEWANELLA ONEIDENSIS MR-1, HYPOTHETICAL PROTEIN, SO2946, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
4qd2:A (ASN594) to (ASN626) MOLECULAR BASIS FOR DISRUPTION OF E-CADHERIN ADHESION BY BOTULINUM NEUROTOXIN A COMPLEX | ORAL TOXICITY, BOTULINUM NEUROTOXIN, E-CADHERIN, HA70, HA17, HA33, CELL ADHESION
3m2v:C (ARG174) to (GLY202) STRUCTURAL INSIGHT INTO METHYL-COENZYME M REDUCTASE CHEMISTRY USING COENZYME B ANALOGUES | METHYL-COENZYME M REDUCTASE, NICKEL, METAL-BINDING, METHANOGENESIS, METHYLATION, TRANSFERASE
3m37:A (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH THE INHIBITOR 1-[2-(AMINOMETHYL) PHENYL]-N-(3-FLUORO-2'-SULFAMOYLBIPHENYL-4-YL)-3- (TRIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXAMIDE (DPC602) | GLYCOPROTEIN, HYDROLASE, SERINE PROTEASE, PLASMA, BLOOD COAGULATION FACTOR, PROTEIN INHIBITOR COMPLEX, CALCIUM- BINDING, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISULFIDE BOND, EGF-LIKE DOMAIN, GAMMA- CARBOXYGLUTAMIC ACID, POLYMORPHISM, PROTEASE, SECRETED, ZYMOGEN
4qen:A (PRO406) to (CYS425) CRYSTAL STRUCTURE OF KRYPTONITE IN COMPLEX WITH MCHH DNA AND SAH | SRA, SET, HISTONE METHYLATION, METHYLATED DNA, TRANSCRIPTION-DNA COMPLEX
4qeo:A (PRO406) to (CYS425) CRYSTAL STRUCTURE OF KRYPTONITE IN COMPLEX WITH MCHH DNA, H3(1-15) PEPTIDE AND SAH | SRA, SET, HISTONE METHYLATION, METHYLATED DNA, METHYLATION, TRANSCRIPTION-DNA COMPLEX
4qep:A (PRO406) to (CYS425) CRYSTAL STRUCTURE OF KRYPTONITE IN COMPLEX WITH MCHG DNA AND SAH | SRA, SET, HISTONE METHYLATION, METHYLATED DNA, METHYLATION, TRANSCRIPTION-DNA COMPLEX
3m3y:A (THR170) to (THR204) RNA POLYMERASE II ELONGATION COMPLEX C | TRANSCRIPTION, MRNA, MULTIPROTEIN COMPLEX, MOLECULAR MACHINE, DNA, DNA DAMAGE, CANCER, PLATINUM DRUG, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, METAL-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
4qf3:A (LYS1931) to (HIS1957) CRYSTAL STRUCTURE OF HUMAN BAZ2B PHD ZINC FINGER IN THE FREE FORM | BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B, KIAA1476, TRANSCRIPTIONAL REGULATION INTERACTING WITH ISWI, TRANSCRIPTION
4qf3:B (LYS1931) to (HIS1957) CRYSTAL STRUCTURE OF HUMAN BAZ2B PHD ZINC FINGER IN THE FREE FORM | BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B, KIAA1476, TRANSCRIPTIONAL REGULATION INTERACTING WITH ISWI, TRANSCRIPTION
5ec5:A (TRP245) to (LEU271) CRYSTAL STRUCTURE OF LYSENIN PORE | INVERTEBRATE CYTOLYSIN, NONAMER, FUNCTIONAL PORE, NANOPORE, TOXIN
5ec5:B (TRP245) to (LEU271) CRYSTAL STRUCTURE OF LYSENIN PORE | INVERTEBRATE CYTOLYSIN, NONAMER, FUNCTIONAL PORE, NANOPORE, TOXIN
5ec5:E (TRP245) to (LEU271) CRYSTAL STRUCTURE OF LYSENIN PORE | INVERTEBRATE CYTOLYSIN, NONAMER, FUNCTIONAL PORE, NANOPORE, TOXIN
5ecn:D (TYR360) to (GLY404) CRYSTAL STRUCTURE OF FIN219-FIP1 COMPLEX WITH JA, LEU AND ATP | JASMONATE-AMIDO SYNTHETASE, GLUTATHIONE S-TRANSFERASE, LIGASE- TRANSFERASE COMPLEX
3m4o:K (LYS18) to (HIS40) RNA POLYMERASE II ELONGATION COMPLEX B | TRANSCRIPTION, MRNA, MULTIPROTEIN COMPLEX, MOLECULAR MACHINE, DNA, DNA DAMAGE, CANCER, PLATINUM DRUG, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, METAL-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
5ecq:D (TYR360) to (GLY404) CRYSTAL STRUCTURE OF FIN219-FIP1 COMPLEX WITH JA, VAL AND ATP | JASMONATE-AMIDO SYNTHETASE, GLUTATHIONE S-TRANSFERASE, LIGASE- TRANSFERASE COMPLEX
3azw:A (VAL895) to (GLN921) CRYSTAL STRUCTURE OF THE RECEPTOR BINDING DOMAIN | BETA-TREFOIL FOLD, BETA-SHEET JELLYROLL FOLD, TOXIN
3azw:B (VAL895) to (GLN921) CRYSTAL STRUCTURE OF THE RECEPTOR BINDING DOMAIN | BETA-TREFOIL FOLD, BETA-SHEET JELLYROLL FOLD, TOXIN
5edv:B (PHE796) to (CYS817) STRUCTURE OF THE HOIP-RBR/UBCH5B~UBIQUITIN TRANSFER COMPLEX | LUBAC, RBR, E3 UBIQUITIN LIGASE, E2, LIGASE-TRANSFERASE COMPLEX
4qg5:D (PRO392) to (ILE413) CRYSTAL STRUCTURE OF PHOSPHOGLUCOMUTASE FROM LEISHMANIA MAJOR AT 3.5 ANGSTROM RESOLUTION | PHOSPHOHEXOMUTASE, PHOSPHOTRANSFERASE, METAL-BINDING REGION, ALPHA AND BETA PROTEINS, ISOMERASE
2a74:D (SER209) to (GLY245) HUMAN COMPLEMENT COMPONENT C3C | IMMUNE SYSTEM
3m7u:A (ILE7) to (ALA34) CRYSTAL STRUCTURE OF ALPHA-LYTIC PROTEASE SB1+2 R64A/E182Q MUTANT | HYDROLASE, DISULFIDE BOND, PROTEASE, SERINE PROTEASE, ZYMOGEN
3b2z:H (ASP456) to (LYS485) CRYSTAL STRUCTURE OF ADAMTS4 (APO FORM) | METALLOPROTEASE, AGGRECANASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, EXTRACELLULAR MATRIX, GLYCOPROTEIN, HYDROLASE, METAL-BINDING, SECRETED, ZYMOGEN
5eft:B (LEU287) to (ILE318) STRUCTURAL BASIS FOR SPECIFIC RECOGNITION OF SSDNA BY SRBSDV P9-1 OCTAMERS | SPECIFIC RECOGNITION, SSDNA, SRBSDV P9-1, OCTAMERS, VIRAL PROTEIN
5eft:D (LEU287) to (ILE318) STRUCTURAL BASIS FOR SPECIFIC RECOGNITION OF SSDNA BY SRBSDV P9-1 OCTAMERS | SPECIFIC RECOGNITION, SSDNA, SRBSDV P9-1, OCTAMERS, VIRAL PROTEIN
5efu:A (ARG57) to (SER84) RESTING STATE OF RAT CYSTEINE DIOXYGENASE H155Q VARIANT | CYSTEINE DIOXYGENASE, NON-HEME MONO-IRON, CUPIN, HISTIDINE TO GLUTAMINE SUBSTITUTION, OXIDOREDUCTASE
5eg8:A (TRP449) to (LYS482) THE CAP BINDING SITE OF INFLUENZA VIRUS PROTEIN PB2 AS A DRUG TARGET | PB2 CAP NATIVE, VIRAL PROTEIN
5eg8:B (TRP449) to (LYS482) THE CAP BINDING SITE OF INFLUENZA VIRUS PROTEIN PB2 AS A DRUG TARGET | PB2 CAP NATIVE, VIRAL PROTEIN
5eg9:A (TRP445) to (LYS478) THE CAP BINDING SITE OF INFLUENZA VIRUS PROTEIN PB2 AS A DRUG TARGET | PB2 CAP, VIRAL PROTEIN
5eg9:B (TRP445) to (SER477) THE CAP BINDING SITE OF INFLUENZA VIRUS PROTEIN PB2 AS A DRUG TARGET | PB2 CAP, VIRAL PROTEIN
4b95:C (GLN73) to (PRO103) PVHL-ELOB-ELOB-ELOCC COMPLEX_(2S,4R)-1-(2-CHLOROPHENYL)CARBONYL-N-[ (4-CHLOROPHENYL)METHYL]-4-OXIDANYL-PYRROLIDINE-2-CARBOXAMIDE BOUND | TRANSCRIPTION, HYPOXIA INDUCIBLE FACTOR, HIF-1ALPHA INHIBITOR
4b95:F (GLN73) to (PRO103) PVHL-ELOB-ELOB-ELOCC COMPLEX_(2S,4R)-1-(2-CHLOROPHENYL)CARBONYL-N-[ (4-CHLOROPHENYL)METHYL]-4-OXIDANYL-PYRROLIDINE-2-CARBOXAMIDE BOUND | TRANSCRIPTION, HYPOXIA INDUCIBLE FACTOR, HIF-1ALPHA INHIBITOR
4b95:L (GLN73) to (PRO103) PVHL-ELOB-ELOB-ELOCC COMPLEX_(2S,4R)-1-(2-CHLOROPHENYL)CARBONYL-N-[ (4-CHLOROPHENYL)METHYL]-4-OXIDANYL-PYRROLIDINE-2-CARBOXAMIDE BOUND | TRANSCRIPTION, HYPOXIA INDUCIBLE FACTOR, HIF-1ALPHA INHIBITOR
4b99:A (GLU54) to (ILE86) CRYSTAL STRUCTURE OF MAPK7 (ERK5) WITH INHIBITOR | TRANSFERASE, INHIBITOR
2aa4:A (MET1) to (ASP26) CRYSTAL STRUCTURE OF ESCHERICHIA COLI PUTATIVE N- ACETYLMANNOSAMINE KINASE, NEW YORK STRUCTURAL GENOMICS CONSORTIUM | SUGAR METHABOLISM, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, TRANSFERASE
4b9y:A (THR607) to (PRO631) CRYSTAL STRUCTURE OF APO AGD31B, ALPHA-TRANSGLUCOSYLASE IN GLYCOSIDE HYDROLASE FAMILY 31 | HYDROLASE
4b9z:A (THR607) to (PRO631) CRYSTAL STRUCTURE OF AGD31B, ALPHA-TRANSGLUCOSYLASE, COMPLEXED WITH ACARBOSE | HYDROLASE
5eim:A (SER390) to (ILE435) YTH DOMAIN-CONTAINING PROTEIN MMI1 AND RNA COMPLEX | MMI1, DSR, YTH, RNA BINDING PROTEIN-RNA COMPLEX
4bb4:A (TYR614) to (LEU649) EPHB4 KINASE DOMAIN INHIBITOR COMPLEX | TRANSFERASE, UNPHOSPHORYLATED
2acx:A (THR185) to (GLU218) CRYSTAL STRUCTURE OF G PROTEIN COUPLED RECEPTOR KINASE 6 BOUND TO AMPPNP | KINASE, G PROTEIN, GRK, G PROTEIN COUPLED RECEPTOR KINASE, GRK6, TRANSFERASE
2acx:B (THR185) to (GLU218) CRYSTAL STRUCTURE OF G PROTEIN COUPLED RECEPTOR KINASE 6 BOUND TO AMPPNP | KINASE, G PROTEIN, GRK, G PROTEIN COUPLED RECEPTOR KINASE, GRK6, TRANSFERASE
2aer:H (GLN30) to (SER54) CRYSTAL STRUCTURE OF BENZAMIDINE-FACTOR VIIA/SOLUBLE TISSUE FACTOR COMPLEX. | SERINE PROTEASE, CALCIUM, MAGNESIUM, ZINC, SODIUM, FACTOR VIIA, TISSUE FACTOR, BENZAMIDINE, BLOOD COAGULATION, CLOTTING, BLOOD, COAGULATION, CLOTTING FACTOR, COAGULATION FACTOR, BLOOD CLOTTING
3b7c:A (ARG87) to (ASP121) CRYSTAL STRUCTURE OF A NTF-2 LIKE PROTEIN OF UNKNOWN FUNCTION (SO_0125) FROM SHEWANELLA ONEIDENSIS MR-1 AT 1.70 A RESOLUTION | NTF-2 LIKE PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
4bbr:B (THR1170) to (GLN1193) STRUCTURE OF RNA POLYMERASE II-TFIIB COMPLEX | TRANSCRIPTION, RNA POLYMERASE, TFIIB
3me9:B (ARG246) to (ALA280) CRYSTAL STRUCTURE OF SGF29 IN COMPLEX WITH H3K4ME3 PEPTIDE | STRUCTURAL GENOMICS CONSORTIUM, SGC, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, CHROMOSOMAL PROTEIN, DNA-BINDING, NUCLEOSOME CORE
3mea:A (ARG246) to (ALA280) CRYSTAL STRUCTURE OF THE SGF29 IN COMPLEX WITH H3K4ME3 | STRUCTURAL GENOMICS CONSORTIUM, SGC, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, CHROMOSOMAL PROTEIN, DNA-BINDING, NUCLEOSOME CORE
4bbs:B (THR1170) to (GLN1193) STRUCTURE OF AN INITIALLY TRANSCRIBING RNA POLYMERASE II- TFIIB COMPLEX | TRANSCRIPTION
4bbv:A (PHE92) to (ARG124) THE PB0 PHOTOCYCLE INTERMEDIATE OF PHOTOACTIVE YELLOW PROTEIN | PHOTORECEPTOR, LIGHT SENSOR, CHROMOPHORE, PHOTORECEPTOR PROTEIN, RECEPTOR, SENSORY TRANSDUCTION, SIGNALING PROTEIN, PAS, LOV
3met:B (ARG246) to (ALA280) CRYSTAL STRUCTURE OF SGF29 IN COMPLEX WITH H3K4ME2 | STRUCTURAL GENOMICS CONSORTIUM, SGC, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, CHROMOSOMAL PROTEIN, DNA-BINDING, NUCLEOSOME CORE
3meu:B (ARG246) to (ALA280) CRYSTAL STRUCTURE OF SGF29 IN COMPLEX WITH H3R2ME2SK4ME3 | STRUCTURAL GENOMICS CONSORTIUM, SGC, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, CHROMOSOMAL PROTEIN, DNA-BINDING, NUCLEOSOME CORE
3mev:B (ARG246) to (ALA280) CRYSTAL STRUCTURE OF SGF29 IN COMPLEX WITH R2AK4ME3 | STRUCTURAL GENOMICS CONSORTIUM, SGC, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, CHROMOSOMAL PROTEIN, DNA-BINDING, NUCLEOSOME CORE
4qmx:A (LEU23) to (ASP56) MST3 IN COMPLEX WITH SARACATINIB | PROTEIN KINASE, MST3, STK24, STERILE 20-LIKE KINASE, ATP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3b8t:A (GLY216) to (SER240) CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT P219A | ALPHA/BETA BARREL, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, ISOMERASE, PEPTIDOGLYCAN SYNTHESIS, PYRIDOXAL PHOSPHATE
3b8t:C (GLY216) to (SER240) CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT P219A | ALPHA/BETA BARREL, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, ISOMERASE, PEPTIDOGLYCAN SYNTHESIS, PYRIDOXAL PHOSPHATE
3b8u:A (GLY216) to (SER240) CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221A | ALPHA/BETA BARREL, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, ISOMERASE, PEPTIDOGLYCAN SYNTHESIS, PYRIDOXAL PHOSPHATE
3b8v:A (GLY216) to (SER240) CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221K | ALPHA/BETA BARREL, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, ISOMERASE, PEPTIDOGLYCAN SYNTHESIS, PYRIDOXAL PHOSPHATE
3b8v:B (GLY216) to (SER240) CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221K | ALPHA/BETA BARREL, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, ISOMERASE, PEPTIDOGLYCAN SYNTHESIS, PYRIDOXAL PHOSPHATE
3b8w:A (GLY216) to (SER240) CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221P | ALPHA/BETA BARREL, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, ISOMERASE, PEPTIDOGLYCAN SYNTHESIS, PYRIDOXAL PHOSPHATE
3b8w:B (GLY216) to (SER240) CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221P | ALPHA/BETA BARREL, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, ISOMERASE, PEPTIDOGLYCAN SYNTHESIS, PYRIDOXAL PHOSPHATE
3b8w:D (GLY216) to (SER240) CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221P | ALPHA/BETA BARREL, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, ISOMERASE, PEPTIDOGLYCAN SYNTHESIS, PYRIDOXAL PHOSPHATE
3mgf:C (MET9) to (MET41) CRYSTAL STRUCTURE OF MONOMERIC KUSABIRA-ORANGE (MKO), ORANGE-EMITTING GFP-LIKE PROTEIN, AT PH 7.5 | FLUORESCENT PROTEIN
3mh0:A (THR7) to (GLY31) MUTAGENESIS OF P38 MAP KINASE ESHTABLISHES KEY ROLES OF PHE169 IN FUNCTION AND STRUCTURAL DYNAMICS AND REVEALS A NOVEL DFG-OUT STATE | SIGNALING PROTEIN,TRANSFERASE, TRANSFERASE
3mh4:A (SER28) to (THR102) HTRA PROTEASES ARE ACTIVATED BY A CONSERVED MECHANISM THAT CAN BE TRIGGERED BY DISTINCT MOLECULAR CUES | DEGP, HTRA, PROTEASE, HYDROLASE
4be4:A (THR13) to (GLY37) CLOSED CONFORMATION OF O. PICEAE STEROL ESTERASE | HYDROLASE
4be9:A (THR13) to (GLY37) OPEN CONFORMATION OF O. PICEAE STEROL ESTERASE | HYDROLASE, OPHIOSTOMA
4be9:B (THR13) to (GLY37) OPEN CONFORMATION OF O. PICEAE STEROL ESTERASE | HYDROLASE, OPHIOSTOMA
3mj1:A (GLU362) to (ILE393) X-RAY CRYSTAL STRUCTURE OF ITK COMPLEXED WITH INHIBITOR RO5191614 | HELIX C-OUT, TRANSFERASE
5epc:A (SER372) to (LEU392) CRYSTAL STRUCTURE OF WILD-TYPE HUMAN PHOSPHOGLUCOMUTASE 1 | ISOMERASE METABOLISM, ISOMERASE
5epc:B (SER372) to (LEU392) CRYSTAL STRUCTURE OF WILD-TYPE HUMAN PHOSPHOGLUCOMUTASE 1 | ISOMERASE METABOLISM, ISOMERASE
3be5:C (VAL61) to (GLY95) CRYSTAL STRUCTURE OF FITE (CRYSTAL FORM 1), A GROUP III PERIPLASMIC SIDEROPHORE BINDING PROTEIN | OPEN FORM, CLOSED FORM, GROUP III PERIPLASMIC BINDING PROTEIN, STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, METAL TRANSPORT
5epn:A (ASP1103) to (LEU1127) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH 5172-MCP1P3 (MK-5172 P1-P3 MACROCYCLIC ANALOGUE) | MACROCYCLIZATION, MK-5172 ANALOGUE, GRAZOPREVIR, HCV PROTEASE INHIBITOR RESISTANCE, HYDROLASE
4beu:A (SER287) to (ARG307) STRUCTURE OF VIBRIO CHOLERAE BROAD SPECTRUM RACEMASE | TRANSFERASE
5eqq:A (ASP1103) to (LEU1127) CRYSTAL STRUCTURE OF HCV NS3/4A WT PROTEASE IN COMPLEX WITH 5172- LINEAR (MK-5172 LINEAR ANALOGUE) | MACROCYCLIZATION, MK-5172 ANALOGUE, GRAZOPREVIR, HCV PROTEASE INHIBITOR RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5eqr:A (ASP1103) to (LEU1127) CRYSTAL STRUCTURE OF A GENOTYPE 1A/3A CHIMERIC HCV NS3/4A PROTEASE IN COMPLEX WITH DANOPREVIR | DANOPREVIR, DRUG RESISTANCE, HCV PROTEASE INHIBITOR, GENOTYPE 3, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5eqs:A (ASP1103) to (LEU1127) CRYSTAL STRUCTURE OF A GENOTYPE 1A/3A CHIMERIC HCV NS3/4A PROTEASE IN COMPLEX WITH ASUNAPREVIR | ASUNAPREVIR, DRUG RESISTANCE, HCV PROTEASE INHIBITOR, GENOTYPE 3, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3bf6:H (GLN30) to (THR54) THROMBIN:SURAMIN COMPLEX | THROMBIN, SURAMIN, BLOOD, COAGULATION, ACUTE PHASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, KRINGLE, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN
4bf5:A (VAL279) to (ARG308) STRUCTURE OF BROAD SPECTRUM RACEMASE FROM AEROMONAS HYDROPHILA | ISOMERASE, D-AMINO ACIDS
4bf5:B (VAL279) to (ARG308) STRUCTURE OF BROAD SPECTRUM RACEMASE FROM AEROMONAS HYDROPHILA | ISOMERASE, D-AMINO ACIDS
3mmg:B (LEU20) to (ASN44) CRYSTAL STRUCTURE OF TOBACCO VEIN MOTTLING VIRUS PROTEASE | 3C-TYPE PROTEASE, TEV, TVMV, VIRAL PROTEIN, HYDROLASE
3mmg:B (ASP107) to (TRP143) CRYSTAL STRUCTURE OF TOBACCO VEIN MOTTLING VIRUS PROTEASE | 3C-TYPE PROTEASE, TEV, TVMV, VIRAL PROTEIN, HYDROLASE
3bg8:A (GLN384) to (THR410) CRYSTAL STRUCTURE OF FACTOR XIA IN COMPLEX WITH CLAVATADINE A | PROTEASE INHIBITOR, FACTOR XIA INHIBITOR COMPLEX, COVALENT INHIBITOR, ALTERNATIVE SPLICING, BLOOD COAGULATION, DISEASE MUTATION, GLYCOPROTEIN, HEPARIN-BINDING, HYDROLASE, POLYMORPHISM, SECRETED, SERINE PROTEASE
4bhn:A (TYR673) to (PRO712) CRYSTAL STRUCTURES OF ASK1-INHIBITOR COMPLEXES | TRANSFERASE, STRUCTURE BASED DESIGN
4bi4:A (VAL120) to (HIS147) STRUCTURE AND FUNCTION OF AMIDASE TOXIN - ANTITOXIN COMBINATIONS ASSOCIATED WITH THE TYPE VI SECRETION SYSTEM OF SERRATIA MARCESCENS. OF SERRATIA MARCESCENS. | TOXIN
4bi4:B (VAL120) to (HIS147) STRUCTURE AND FUNCTION OF AMIDASE TOXIN - ANTITOXIN COMBINATIONS ASSOCIATED WITH THE TYPE VI SECRETION SYSTEM OF SERRATIA MARCESCENS. OF SERRATIA MARCESCENS. | TOXIN
4bi8:B (VAL120) to (HIS147) CRYSTAL STRUCTURE OF THE TYPE VI EFFECTOR-IMMUNITY COMPLEX SSP1-RAP1A FROM SERRATIA MARCESCENS | TOXIN, PROTEIN RAP1A COMPLEX
3bgt:A (PRO57) to (LEU95) STRUCTURAL STUDIES OF ACETOACETATE DECARBOXYLASE | ACETOACETATE DECARBOXYLASE, LYASE, SCHIFF BASE
3bgt:D (PRO57) to (LEU95) STRUCTURAL STUDIES OF ACETOACETATE DECARBOXYLASE | ACETOACETATE DECARBOXYLASE, LYASE, SCHIFF BASE
4qt8:D (LEU665) to (THR695) CRYSTAL STRUCTURE OF RON SEMA-PSI-IPT1 EXTRACELLULAR DOMAINS IN COMPLEX WITH MSP BETA-CHAIN | GROWTH FACTOR RECEPTOR/GROWTH FACTOR, RECEPTOR-LIGAND COMPLEX, RON RECEPTOR TYROSINE KINASE, MACROPHAGE STIMULATING PROTEIN, HYDROLASE- SIGNALING PROTEIN COMPLEX
3bh2:B (PRO56) to (HIS94) STRUCTURAL STUDIES OF ACETOACETATE DECARBOXYLASE | ACETOACETATE DECARBOXYLASE, LYASE, PLASMID, SCHIFF BASE
3bh2:D (PRO56) to (HIS94) STRUCTURAL STUDIES OF ACETOACETATE DECARBOXYLASE | ACETOACETATE DECARBOXYLASE, LYASE, PLASMID, SCHIFF BASE
3bh3:A (PRO57) to (LEU95) CRYSTAL STRUCTURE OF ACETOACETATE DECARBOXYLASE FROM CHROMOBACTERIUM VIOLACEUM IN COMPLEX WITH ACETYL ACETONE SCHIFF BASE INTERMEDIATE | ACETOACETATE DECARBOXYLASE, SCHIFF BASE INTERMEDIATE, LYASE
3bh3:B (PRO57) to (LEU95) CRYSTAL STRUCTURE OF ACETOACETATE DECARBOXYLASE FROM CHROMOBACTERIUM VIOLACEUM IN COMPLEX WITH ACETYL ACETONE SCHIFF BASE INTERMEDIATE | ACETOACETATE DECARBOXYLASE, SCHIFF BASE INTERMEDIATE, LYASE
3bh3:D (PRO57) to (LEU95) CRYSTAL STRUCTURE OF ACETOACETATE DECARBOXYLASE FROM CHROMOBACTERIUM VIOLACEUM IN COMPLEX WITH ACETYL ACETONE SCHIFF BASE INTERMEDIATE | ACETOACETATE DECARBOXYLASE, SCHIFF BASE INTERMEDIATE, LYASE
5etx:A (LEU1104) to (LEU1127) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE A156T VARIANT IN COMPLEX WITH 5172-LINEAR (MK-5172 LINEAR ANALOGUE) | MACROCYCLIZATION, MK-5172 ANALOGUE, GRAZOPREVIR, HCV PROTEASE INHIBITOR RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5etx:B (LEU1104) to (LEU1127) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE A156T VARIANT IN COMPLEX WITH 5172-LINEAR (MK-5172 LINEAR ANALOGUE) | MACROCYCLIZATION, MK-5172 ANALOGUE, GRAZOPREVIR, HCV PROTEASE INHIBITOR RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5etx:C (LEU1104) to (LEU1127) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE A156T VARIANT IN COMPLEX WITH 5172-LINEAR (MK-5172 LINEAR ANALOGUE) | MACROCYCLIZATION, MK-5172 ANALOGUE, GRAZOPREVIR, HCV PROTEASE INHIBITOR RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5etz:A (GLY104) to (GLY122) STRUCTURE OF THE ALL-TRANS ISOMER OF PHARAONIS HALORHODOPSIN IN THE ABSENCE OF HALIDE IONS | RETINAL PROTEIN, LIGHT-DRIVEN, CHLORIDE ION PUMP, SEVEN- TRANSMEMBRANE, ALPHA HELICES, MEMBRANE PROTEIN
3biu:H (GLN30) to (THR54) HUMAN THROMBIN-IN COMPLEX WITH UB-THR10 | SERINE PROTEASE-INHIBITOR COMPLEX, BLOOD CLOTTING, ACUTE PHASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, KRINGLE, SECRETED, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4quz:A (LEU510) to (ALA536) CRYSTAL STRUCTURE OF FELINE NOROVIRUS P DOMAIN | FELINE NOROVIRUS, VIRAL CAPSID PROTEIN, P DOMAIN, PROTRUDING DOMAIN, VIRAL PROTEIN
4quz:B (LEU510) to (ALA536) CRYSTAL STRUCTURE OF FELINE NOROVIRUS P DOMAIN | FELINE NOROVIRUS, VIRAL CAPSID PROTEIN, P DOMAIN, PROTRUDING DOMAIN, VIRAL PROTEIN
3mru:B (PRO99) to (ALA118) CRYSTAL STRUCTURE OF AMINOACYLHISTIDINE DIPEPTIDASE FROM VIBRIO ALGINOLYTICUS | METALLOPROTEASE, HOMODIMER, HYDROLASE
5ew1:H (GLN30) to (THR54) HUMAN THROMBIN SANDWICHED BETWEEN TWO DNA APTAMERS: HD22 AND HD1- DELTAT3 | PROTEIN-DNA COMPLEX, BLOOD COAGULATION, DNA APTAMER, DNA-INHIBITOR, G-QUADRUPLEX, DUPLEX-QUADRUPLEX JUNCTION, SERINE PROTEASE, HYDROLASE, ABASIC FURAN, HYDROLASE-DNA COMPLEX
5ew2:H (GLN30) to (THR54) HUMAN THROMBIN SANDWICHED BETWEEN TWO DNA APTAMERS: HD22 AND HD1- DELTAT12 | PROTEIN-DNA COMPLEX, BLOOD COAGULATION, DNA APTAMER, DNA-INHIBITOR, G-QUADRUPLEX, DUPLEX-QUADRUPLEX JUNCTION, SERINE PROTEASE, HYDROLASE, ABASIC FURAN, HYDROLASE-DNA COMPLEX
3ms9:B (ASP241) to (LEU273) ABL KINASE IN COMPLEX WITH IMATINIB AND A FRAGMENT (FRAG1) IN THE MYRISTATE POCKET | KINASE, FRAGMENT-BASED SCREENING, FBS, TRANSFERASE, TRANSFERASE- TRANSFERASE REGULATOR COMPLEX
5ewn:B (THR309) to (THR329) CRYSTAL STRUCTURE OF THE HUMAN ASTROVIRUS 1 CAPSID PROTEIN CORE DOMAIN AT 2.6 A RESOLUTION | VIRUS PROTEIN, CAPSID PROTEIN, ICOSAHEDRAL VIRUS, JELLY-ROLL, VIRAL PROTEIN
3mss:A (ASP241) to (LEU273) ABL KINASE IN COMPLEX WITH IMATINIB AND FRAGMENT (FRAG2) IN THE MYRISTATE SITE | KINASE, FRAGMENT-BASED SCREENING, FBS, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3mss:D (ASP241) to (LEU273) ABL KINASE IN COMPLEX WITH IMATINIB AND FRAGMENT (FRAG2) IN THE MYRISTATE SITE | KINASE, FRAGMENT-BASED SCREENING, FBS, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4qvj:A (LEU510) to (ALA536) UNLIGANDED CRYSTAL STRUCTURE OF FELINE NOROVIRUS P DOMAIN CO- CRYSTALLIZED WITH N-ACETYLNEURAMINIC ACID | FELINE NOROVIRUS, VIRAL CAPSID PROTEIN, P DOMAIN, PROTRUDING DOMAIN, VIRAL PROTEIN
4qvj:B (LEU510) to (ALA536) UNLIGANDED CRYSTAL STRUCTURE OF FELINE NOROVIRUS P DOMAIN CO- CRYSTALLIZED WITH N-ACETYLNEURAMINIC ACID | FELINE NOROVIRUS, VIRAL CAPSID PROTEIN, P DOMAIN, PROTRUDING DOMAIN, VIRAL PROTEIN
5exw:A (GLY28) to (TYR65) CRYSTAL STRUCTURE OF HUMAN GRP78 (70KDA HEAT SHOCK PROTEIN 5 / BIP) ATPASE DOMAIN IN COMPLEX WITH 7-DEAZA-ATP | CHAPERONE, ATPASE DOMAIN, NUCLEOTIDE-BINDING, ENDOPLASMIC RETICULUM
5eyk:B (ASP92) to (PHE125) CRYSTAL STRUCTURE OF AURORA B IN COMPLEX WITH BI 847325 | KINASE, INHIBITOR, TRANSFERASE
4bmk:A (GLU52) to (LEU70) SERINE PALMITOYLTRANSFERASE K265A FROM S. PAUCIMOBILIS WITH BOUND PLP-MYRIOCIN ALDIMINE | TRANSFERASE-ANTIBIOTIC COMPLEX, TRANSFERASE, EXTERNAL ALDIMINE, INHIBITOR, SPHINGOLIPIDS, NATURAL PRODUCT, ANTIBIOTIC ISP-1
3bnc:A (SER39) to (GLY89) LIPOXYGENASE-1 (SOYBEAN) I553G MUTANT | DIOXYGENASE, LIPOXYGENASE, METALLOPROTEIN, FATTY ACIDS, FATTY ACID BIOSYNTHESIS, IRON, LIPID SYNTHESIS, METAL-BINDING, OXIDOREDUCTASE, OXYLIPIN BIOSYNTHESIS, ----
3bne:A (SER39) to (GLU86) LIPOXYGENASE-1 (SOYBEAN) I553A MUTANT | DIOXYGENASE, LIPOXYGENASE, METALLOPROTEIN, FATTY ACIDS, FATTY ACID BIOSYNTHESIS, IRON, LIPID SYNTHESIS, METAL-BINDING, OXIDOREDUCTASE, OXYLIPIN BIOSYNTHESIS, ----
5ezv:A (TYR16) to (ASN48) X-RAY CRYSTAL STRUCTURE OF AMP-ACTIVATED PROTEIN KINASE ALPHA-2/ALPHA- 1 RIM CHIMAERA (ALPHA-2(1-347)/ALPHA-1(349-401)/ALPHA-2(397-END) BETA-1 GAMMA-1) CO-CRYSTALLIZED WITH C2 (5-(5-HYDROXYL-ISOXAZOL-3- YL)-FURAN-2-PHOSPHONIC ACID) | TRANSFERASE, SERINE/THREONINE KINASE, ALLOSTERIC ACTIVATION, NUCLEOTIDE-BINDING
5ezw:A (ARG57) to (SER84) THIOSULFATE BOUND RAT CYSTEINE DIOXYGENASE Y157H VARIANT | THIOETHER BOND, POST-TRANSLATIONAL MODIFICATION, POST TRANSLATIONAL, POSTTRANSLATIONAL, CYSTEINE DIOXYGENASE, NON-HEME MONO-IRON, CUPIN, TYROSINE TO HISTIDINE SUBSTITUTION, BETA BARREL, OXIDOREDUCTASE
3bpu:A (PHE655) to (GLU688) CRYSTAL STRUCTURE OF THE 3RD PDZ DOMAIN OF HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASE, C677S AND C709S DOUBLE MUTANT | PDZ, MEMBRANE ASSOCIATED GUANYLATE KINASE, STRUCTURAL GENOMICS CONSORTIUM, SGC, ATP-BINDING, CELL JUNCTION, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TIGHT JUNCTION, TRANSFERASE
3bt7:A (MET46) to (ASP75) STRUCTURE OF E. COLI 5-METHYLURIDINE METHYLTRANSFERASE TRMA IN COMPLEX WITH 19 NUCLEOTIDE T-ARM ANALOGUE | METHYLURIDINE, METHYLTRANSFERASE, TRMA, RUMT, S-ADENOSYL-L- METHIONINE, TRNA PROCESSING, TRANSFERASE-RNA COMPLEX
3bt7:B (MET46) to (ASP75) STRUCTURE OF E. COLI 5-METHYLURIDINE METHYLTRANSFERASE TRMA IN COMPLEX WITH 19 NUCLEOTIDE T-ARM ANALOGUE | METHYLURIDINE, METHYLTRANSFERASE, TRMA, RUMT, S-ADENOSYL-L- METHIONINE, TRNA PROCESSING, TRANSFERASE-RNA COMPLEX
5f4j:A (ASP471) to (ALA500) PROTRUDING DOMAIN OF GII.17 NOROVIRUS SAITAMA/T87 | NOROVIRUS, VIRUS CAPSID, PROTRUDING DOMAIN, VIRAL PROTEIN
3mx0:A (PRO221) to (VAL255) CRYSTAL STRUCTURE OF EPHA2 ECTODOMAIN IN COMPLEX WITH EPHRIN-A5 | ECTODOMAIN, RECEPTOR-LIGAND COMPLEX, RECEPTOR-RECEPTOR INTERACTION, TRANSFERASE RECEPTOR-SIGNALLING PROTEIN COMPLEX
5f7s:A (ARG669) to (TYR693) CYCLOALTERNAN-DEGRADING ENZYME FROM TRUEPERELLA PYOGENES | HYDROLASE, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
3myw:A (GLN30) to (SER54) THE BOWMAN-BIRK TYPE INHIBITOR FROM MUNG BEAN IN TERNARY COMPLEX WITH PORCINE TRYPSIN | SERINE PROTEINASE, BOWMAN-BIRK-TYPE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3myw:B (GLN30) to (SER54) THE BOWMAN-BIRK TYPE INHIBITOR FROM MUNG BEAN IN TERNARY COMPLEX WITH PORCINE TRYPSIN | SERINE PROTEINASE, BOWMAN-BIRK-TYPE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3bwl:C (GLY474) to (ASP507) CRYSTAL STRUCTURE OF PAS DOMAIN OF HTR-LIKE PROTEIN FROM HALOARCULA MARISMORTUI | STRUCTURAL GENOMICS, APC87707.1, PAS DOMAIN, HTR-LIKE PROTEIN, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, KINASE, PHOSPHOPROTEIN, TRANSFERASE
3bwl:D (GLY474) to (ASP507) CRYSTAL STRUCTURE OF PAS DOMAIN OF HTR-LIKE PROTEIN FROM HALOARCULA MARISMORTUI | STRUCTURAL GENOMICS, APC87707.1, PAS DOMAIN, HTR-LIKE PROTEIN, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, KINASE, PHOSPHOPROTEIN, TRANSFERASE
5f9c:A (SER372) to (LEU392) CRYSTAL STRUCTURE OF THE G121R MUTANT OF HUMAN PHOSPHOGLUCOMUTASE 1 | ISOMERASE METABOLISM, ISOMERASE
5f9c:B (SER372) to (LEU392) CRYSTAL STRUCTURE OF THE G121R MUTANT OF HUMAN PHOSPHOGLUCOMUTASE 1 | ISOMERASE METABOLISM, ISOMERASE
3n25:F (SER171) to (ASN198) THE STRUCTURE OF MUSCLE PYRUVATE KINASE IN COMPLEX WITH PROLINE, PYRUVATE, AND MN2+ | PYRUVATE KINASE, GLYCOLYSIS, ALLOSTERIC REGULATION, TRANSFERASE
3by1:A (GLU455) to (VAL484) UNLIGANDED NORVALK VIRUS P DOMAIN | NORWALK VIRUS P DOMAIN, VIRAL PROTEIN
3bz3:A (ARG421) to (CYS456) CRYSTAL STRUCTURE ANALYSIS OF FOCAL ADHESION KINASE WITH A METHANESULFONAMIDE DIAMINOPYRIMIDINE INHIBITOR | KINASE, DFG-HELIX, ACETYLATION, ALTERNATIVE SPLICING, ATP- BINDING, CELL JUNCTION, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE, TYROSINE-PROTEIN KINASE
4btt:F (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH THE DUAL THROMBIN-FXA INHIBITOR 31. | HYDROLASE, SAR107375, FACTOR XA INHIBITOR, THROMBIN INHIBITOR, CHLOROTHIOPHENE P1 FRAGMENT, S3 SUBSITE, MICROSOMES STABILITY, ORAL ANTITHROMBOTIC, DUAL INHIBITOR, IV ANTITHROMBOTIC
4btu:F (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH THE DUAL THROMBIN-FXA INHIBITOR 57. | HYDROLASE, SAR107375, FACTOR XA INHIBITOR, THROMBIN INHIBITOR, CHLOROTHIOPHENE P1 FRAGMENT, S3 SUBSITE, MICROSOMES STABILITY, ORAL ANTITHROMBOTIC, DUAL INHIBITOR, IV ANTITHROMBOTIC
3c0t:A (SER121) to (ALA174) STRUCTURE OF THE SCHIZOSACCHAROMYCES POMBE MEDIATOR SUBCOMPLEX MED8C/18 | BETA BARREL, CHANNEL, PROTEIN-PROTEIN COMPLEX, ACTIVATOR, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION
3n3i:A (PRO9) to (GLU34) CRYSTAL STRUCTURE OF G48V/C95F TETHERED HIV-1 PROTEASE/SAQUINAVIR COMPLEX | HIV-1 PROTEASE, SAQUINAVIR, DRUG RESISTANCE, TETHERED-DIMER, FUSION PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3n3t:A (GLU503) to (PRO538) CRYSTAL STRUCTURE OF PUTATIVE DIGUANYLATE CYCLASE/PHOSPHODIESTERASE COMPLEX WITH CYCLIC DI-GMP | GGDEF & EAL DOMAINS, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
3n41:F (GLY0) to (PRO40) CRYSTAL STRUCTURE OF THE MATURE ENVELOPE GLYCOPROTEIN COMPLEX (SPONTANEOUS CLEAVAGE) OF CHIKUNGUNYA VIRUS. | VIRAL PROTEIN, IMMATURE HETERODIMER, ALPHAVIRUS, RECEPTOR BINDING, MEMBRANE FUSION
5fbi:A (MET30) to (SER54) COMPLEMENT FACTOR D IN COMPLEX WITH COMPOUND 3B | HYDROLASE
3c27:B (GLN51) to (THR76) CYANOFLUOROPHENYLACETAMIDES AS ORALLY EFFICACIOUS THROMBIN INHIBITORS | THROMBIN, SERINE PROTEASE, ACUTE PHASE, BLOOD COAGULATION, GAMMA- CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, KRINGLE, PROTEASE, SECRETED, ZYMOGEN, PROTEASE INHIBITOR, SERINE PROTEASE INHIBITOR, SULFATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3c2i:A (GLY103) to (ARG133) THE CRYSTAL STRUCTURE OF METHYL-CPG BINDING DOMAIN OF HUMAN MECP2 IN COMPLEX WITH A METHYLATED DNA SEQUENCE FROM BDNF | WATER MEDIATED RECOGNITION, PROTEIN-METHYLATED DNA COMPLEX, ASX-ST-MOTIF, ALTERNATIVE SPLICING, CHROMOSOMAL REARRANGEMENT, DISEASE MUTATION, DNA-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, REPRESSOR, TRANSCRIPTION REGULATOR
5fck:A (MET30) to (SER54) COMPLEMENT FACTOR D IN COMPLEX WITH COMPOUND 5 | HYDROLASE
4r3z:C (ASP739) to (ARG764) CRYSTAL STRUCTURE OF HUMAN ARGRS-GLNRS-AIMP1 COMPLEX | AMINO-ACYL TRNA SYNTHETASE COMPLEX, MULTI-SYNTHETASE COMPLEX, LIGATION AMINO ACID TO TRNA, PROTEIN BINDING-LIGASE COMPLEX
4bxw:A (GLN184) to (LEU207) CRYSTAL STRUCTURE OF THE PROTHROMBINASE COMPLEX FROM THE VENOM OF PSEUDONAJA TEXTILIS | BLOOD CLOTTING, BLOOD COAGULATION, PROTHROMBINASE, FACTOR V, FACTOR X, HYDROLASE, PROTEASE
3c4y:B (TRP186) to (ASN219) CRYSTAL STRUCTURE OF APO FORM OF G PROTEIN COUPLED RECEPTOR KINASE 1 AT 7.51A | SER/THR KINASE, RGS HOMOLOGY DOMAIN, G PROTEIN COUPLED RECEPTOR KINASE, GRK, GRK1, RHODOPSIN KINASE, P-LOOP, AUTOPHOSPHORYLATION, ATP-BINDING, LIPOPROTEIN, MEMBRANE, METHYLATION, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PRENYLATION, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3n7o:A (TYR29) to (THR54) X-RAY STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH SMALL MOLECULE INHIBITOR. | SERINE PROTEASE, HYDROLASE
5fhc:K (TYR214) to (GLU245) CRYSTAL STRUCTURE OF PROTECTIVE HUMAN ANTIBODIES 100 AND 114 IN COMPLEX WITH EBOLA VIRUS FUSION GLYCOPROTEIN (GP) | IG DOMAIN, FAB, IMMUNE SYSTEM, FUSION, EBOLA VIRUS, GLYCOPROTEIN, GP, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
4r71:E (ASP34) to (GLU76) STRUCTURE OF THE QBETA HOLOENZYME COMPLEX IN THE P1211 CRYSTAL FORM | OB FOLD, TRANSLATION, VIRAL PROTEIN-RIBOSOMAL PROTEIN COMPLEX
5fi0:C (GLN287) to (GLY329) CRYSTAL STRUCTURE OF THE P-REX1 DH/PH TANDEM IN COMPLEX WITH RAC1 | DBL HOMOLOGY DOMAIN, PLECKSTRIN HOMOLOGY DOMAIN, BETA SANDWICH, SMALL GTPASE, PROTEIN BINDING
5fix:A (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH SUCROSE | AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYTIC DOMAIN, DIMERIZATION, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, SUBSTRATE SPECIFICITY, INVERTASE, PREBIOTICS, SUCROSE, HYDROLASE
5fix:B (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH SUCROSE | AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYTIC DOMAIN, DIMERIZATION, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, SUBSTRATE SPECIFICITY, INVERTASE, PREBIOTICS, SUCROSE, HYDROLASE
3n9x:A (ASN27) to (ARG61) CRYSTAL STRUCTURE OF MAP KINASE FROM PLASMODIUM BERGHEI, PB000659.00.0 | MALARIA KINASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
4r8t:B (GLY21) to (LEU49) STRUCTURE OF JEV PROTEASE | SERINE PROTEASE, PROTEASE, NS2B, HYDROLASE
3cce:Q (GLU37) to (GLY78) STRUCTURE OF ANISOMYCIN RESISTANT 50S RIBOSOMAL SUBUNIT: 23S RRNA MUTATION U2535A | 23S RRNA MUTATION U2535A, RIBOSOME
3ccj:N (LYS31) to (LEU58) STRUCTURE OF ANISOMYCIN RESISTANT 50S RIBOSOMAL SUBUNIT: 23S RRNA MUTATION C2534U | C2534U MUTATION, 23S RRNA, LARGE RIBOSOMAL SUBUNIT, RIBOSOME
3ccm:N (LYS31) to (LEU58) STRUCTURE OF ANISOMYCIN RESISTANT 50S RIBOSOMAL SUBUNIT: 23S RRNA MUTATION G2611U | G2611U MUTATION, 23S RRNA, LARGE RIBOSOMAL SUBUNIT, RIBOSOME
3ccq:N (LYS31) to (LEU58) STRUCTURE OF ANISOMYCIN RESISTANT 50S RIBOSOMAL SUBUNIT: 23S RRNA MUTATION A2488U | GENOMIC SEQUNECE FOR R-PROTEINS, RIBOSOME
5fk7:A (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NEOKESTOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, NEOKESTOSE
5fk7:B (TYR157) to (LEU198) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NEOKESTOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, NEOKESTOSE
5fk7:B (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NEOKESTOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, NEOKESTOSE
5fk8:A (TYR157) to (LEU198) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NEO-ERLOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, NEOERLOSE
5fk8:A (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NEO-ERLOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, NEOERLOSE
5fk8:B (TYR157) to (LEU198) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NEO-ERLOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, NEOERLOSE
5fk8:B (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NEO-ERLOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, NEOERLOSE
4rct:A (PHE262) to (SER286) CRYSTAL STRUCTURE OF R-PROTEIN OF NGOAVII RESTRICTION ENDONUCLEASE | RESTRICTION ENDONUCLEASE, B3 DOMAIN, PLD NUCLEASE, HYDROLASE
4rct:B (PHE262) to (SER286) CRYSTAL STRUCTURE OF R-PROTEIN OF NGOAVII RESTRICTION ENDONUCLEASE | RESTRICTION ENDONUCLEASE, B3 DOMAIN, PLD NUCLEASE, HYDROLASE
5fkb:A (TYR157) to (LEU198) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH 1-KESTOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, 1-KESTOSE
5fkb:A (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH 1-KESTOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, 1-KESTOSE
5fkb:B (TYR157) to (LEU198) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH 1-KESTOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, 1-KESTOSE
5fkb:B (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH 1-KESTOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, 1-KESTOSE
5fkc:A (TYR157) to (LEU198) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH RAFFINOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, RAFFINOSE
5fkc:A (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH RAFFINOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, RAFFINOSE
5fkc:B (TYR157) to (LEU198) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH RAFFINOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, RAFFINOSE
5fkc:B (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH RAFFINOSE | HYDROLASE, AMINO ACID SEQUENCE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, RAFFINOSE
4rd5:A (PHE262) to (SER286) CRYSTAL STRUCTURE OF R.NGOAVII RESTRICTION ENDONUCLEASE B3 DOMAIN WITH COGNATE DNA | RESTRICTION ENDONUCLEASE, B3 DNA BINDING DOMAIN, PROTEIN-DNA COMPLEX, HYDROLASE-DNA COMPLEX
4rd5:B (PHE262) to (SER286) CRYSTAL STRUCTURE OF R.NGOAVII RESTRICTION ENDONUCLEASE B3 DOMAIN WITH COGNATE DNA | RESTRICTION ENDONUCLEASE, B3 DNA BINDING DOMAIN, PROTEIN-DNA COMPLEX, HYDROLASE-DNA COMPLEX
4rdm:A (PHE262) to (SER286) CRYSTAL STRUCTURE OF R.NGOAVII RESTRICTION ENDONUCLEASE B3 DOMAIN WITH COGNATE DNA | RESTRICTION ENDONUCLEASE, B3 DOMAIN, PROTEIN-DNA COMPLEX, HYDROLASE- DNA COMPLEX
4rdm:B (PHE262) to (SER286) CRYSTAL STRUCTURE OF R.NGOAVII RESTRICTION ENDONUCLEASE B3 DOMAIN WITH COGNATE DNA | RESTRICTION ENDONUCLEASE, B3 DOMAIN, PROTEIN-DNA COMPLEX, HYDROLASE- DNA COMPLEX
3ncw:B (LEU756) to (GLY771) CRYSTAL STRUCTURE OF EHEC O157:H7 INTIMIN | CELL MEMBRANE, CELL ADHESION, IMMUNOGLOBULIN-LIKE FOLD, C-TYPE AND LECTIN-LIKE FOLD
3ch8:A (PHE6) to (GLN49) THE CRYSTAL STRUCTURE OF PDZ-FIBRONECTIN FUSION PROTEIN | FIBRONECTIN, PDZ, STRUCTURAL PROTEIN
3nff:F (SER78) to (SER137) CRYSTAL STRUCTURE OF EXTENDED DIMERIZATION MODULE OF RNA POLYMERASE I SUBCOMPLEX A49/A34.5 | TRIPLE BARREL, TRANSCRIPTION, RNA POLYMERASE, DIMERIZATION
4rfq:A (ASN115) to (GLU163) HUMAN METHYLTRANSFERASE-LIKE 18 | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
5flm:K (LYS18) to (HIS40) STRUCTURE OF TRANSCRIBING MAMMALIAN RNA POLYMERASE II | TRANSCRIPTION, ELONGATION
5fmb:A (TYR157) to (LEU198) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH FRUCTOSE AND HEPES BUFFER | HYDROLASE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR CONFORMATION, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, FRUCTOSE, HEPES BUFFER
5fmb:A (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH FRUCTOSE AND HEPES BUFFER | HYDROLASE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR CONFORMATION, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, FRUCTOSE, HEPES BUFFER
5fmb:B (TYR157) to (LEU198) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH FRUCTOSE AND HEPES BUFFER | HYDROLASE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR CONFORMATION, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, FRUCTOSE, HEPES BUFFER
5fmb:B (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH FRUCTOSE AND HEPES BUFFER | HYDROLASE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR CONFORMATION, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, FRUCTOSE, HEPES BUFFER
5fmc:A (TYR157) to (LEU198) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH FRUCTOSE AND BIS-TRIS PROPANE BUFFER | HYDROLASE, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, FRUCTOSE, BUFFER, BIS-TRIS PROPANE
5fmc:A (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH FRUCTOSE AND BIS-TRIS PROPANE BUFFER | HYDROLASE, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, FRUCTOSE, BUFFER, BIS-TRIS PROPANE
5fmc:B (TYR157) to (LEU198) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH FRUCTOSE AND BIS-TRIS PROPANE BUFFER | HYDROLASE, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, FRUCTOSE, BUFFER, BIS-TRIS PROPANE
5fmc:B (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH FRUCTOSE AND BIS-TRIS PROPANE BUFFER | HYDROLASE, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR, MOLECULAR CONFORMATION, PROTEIN CONFORMATION, PROTEIN STRUCTURE, SECONDARY, SUBSTRATE SPECIFICITY, BETA-FRUCTOFURANOSIDASE, INVERTASE, PREBIOTICS, FRUCTOSE, BUFFER, BIS-TRIS PROPANE
5fmd:A (TYR157) to (LEU198) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NYSTOSE | HYDROLASE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR CONFORMATION, SUBSTRATE SPECIFICITY, INVERTASE, PREBIOTICS, NYSTOSE
5fmd:A (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NYSTOSE | HYDROLASE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR CONFORMATION, SUBSTRATE SPECIFICITY, INVERTASE, PREBIOTICS, NYSTOSE
5fmd:B (TYR157) to (LEU198) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NYSTOSE | HYDROLASE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR CONFORMATION, SUBSTRATE SPECIFICITY, INVERTASE, PREBIOTICS, NYSTOSE
5fmd:B (ASP246) to (LEU279) STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NYSTOSE | HYDROLASE, CARBOHYDRATES, CATALYSIS, CATALYTIC DOMAIN, CLONING, DIMERIZATION, QUATERNARY, PICHIA PASTORIS, GLYCOSIDE HYDROLASES, FUNGAL PROTEINS, KINETICS, MOLECULAR CONFORMATION, SUBSTRATE SPECIFICITY, INVERTASE, PREBIOTICS, NYSTOSE
4rh6:A (ILE131) to (LEU159) 2.9 ANGSTROM CRYSTAL STRUCTURE OF PUTATIVE EXOTOXIN 3 FROM STAPHYLOCOCCUS AUREUS. | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, SUPERANTIGEN-LIKE PROTEIN, EXOTOXIN 3, TOXIN
4rh6:B (ILE131) to (LEU159) 2.9 ANGSTROM CRYSTAL STRUCTURE OF PUTATIVE EXOTOXIN 3 FROM STAPHYLOCOCCUS AUREUS. | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, SUPERANTIGEN-LIKE PROTEIN, EXOTOXIN 3, TOXIN
3cma:N (LYS31) to (LEU58) THE STRUCTURE OF CCA AND CCA-PHE-CAP-BIO BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF HALOARCULA MARISMORTUI | RIBOSOME 50S, PROTEIN-PROTEIN COMPLEX, RNA-RNA COMPLEX, PROTEIN-RNA COMPLEX, PEPTIDYL-TRNA HYDROLYSIS, RIBOSOME
3cme:N (LYS31) to (LEU58) THE STRUCTURE OF CA AND CCA-PHE-CAP-BIO BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF HALOARCULA MARISMORTUI | RIBOSOME 50S, PROTEIN-PROTEIN COMPLEX, RNA-RNA COMPLEX, PROTEIN-RNA COMPLEX, HYDROLYSIS OF PEPTIDYL-TRNA, RIBOSOME
4ri0:C (VAL155) to (THR188) SERINE PROTEASE HTRA3, MUTATIONALLY INACTIVATED | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, NATIONAL SCIENCE CENTER - POLAND, PROTEASE, HYDROLASE
4cb4:A (TRP449) to (LYS482) STRUCTURE OF INFLUENZA A H5N1 PB2 CAP-BINDING DOMAIN WITH BOUND M7GTP | TRANSFERASE, CAP-BINDING INHIBITORS
4cb6:A (TRP449) to (LYS482) STRUCTURE OF INFLUENZA A H5N1 PB2 CAP-BINDING DOMAIN WITH BOUND CAP ANALOGUE (COMPOUND 11) | TRANSFERASE, INFLUENZA POLYMERASE, M7GTP, CAP-BINDING INHIBITORS
4cb6:B (TRP449) to (LYS482) STRUCTURE OF INFLUENZA A H5N1 PB2 CAP-BINDING DOMAIN WITH BOUND CAP ANALOGUE (COMPOUND 11) | TRANSFERASE, INFLUENZA POLYMERASE, M7GTP, CAP-BINDING INHIBITORS
4cb7:A (TRP445) to (SER477) STRUCTURE OF INFLUENZA A H5N1 PB2 CAP-BINDING DOMAIN WITH BOUND CAP ANALOGUE (COMPOUND 8E) | TRANSCRIPTION, CAP-BINDING INHIBITORS
4cbo:B (MET15) to (SER38) CRYSTAL STRUCTURE OF COMPLEMENT FACTOR D MUTANT R202A AFTER ENSEMBLE REFINEMENT | HYDROLASE, FACTOR D, ENSEMBLE REFINEMENT
4rko:B (GLN30) to (THR54) CRYSTAL STRUCTURE OF THROMBIN MUTANT S195T BOUND WITH PPACK | TRYPSIN-LIKE PROTEASES, CATALYSIS, ALLOSTERIC REGULATION, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4rkx:A (HIS340) to (ARG368) IDENTIFICATION AND CHARACTERIZATION OF A SMALL MOLECULE INHIBITOR OF S. PYOGENES SPEB. | PAPAIN FOLD, CYSTEINE PROTEASE, SECRETED, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3nqi:D (GLY35) to (PRO58) CRYSTAL STRUCTURE OF A PUTATIVE LIPOPROTEIN (BF3042) FROM BACTEROIDES FRAGILIS NCTC 9343 AT 1.87 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LIPID BINDING PROTEIN
3nrl:A (PHE37) to (VAL59) CRYSTAL STRUCTURE OF PROTEIN RUMGNA_01417 FROM RUMINOCOCCUS GNAVUS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET UGR76 | BETA PROTEIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
3nrl:B (PHE37) to (VAL59) CRYSTAL STRUCTURE OF PROTEIN RUMGNA_01417 FROM RUMINOCOCCUS GNAVUS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET UGR76 | BETA PROTEIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
4rny:B (ASN206) to (ALA227) STRUCTURE OF HELICOBACTER PYLORI CSD3 FROM THE ORTHORHOMBIC CRYSTAL | M23B METALLOPEPTIDASE, METALLOPEPTIDASE, PEPTIDOGLYCAN, HYDROLASE
3ntp:A (PRO9) to (TRP34) HUMAN PIN1 COMPLEXED WITH REDUCED AMIDE INHIBITOR | PROLYL ISOMERASE, PHOSPHORYLATION REGULATION, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
4rpb:A (GLU473) to (SER502) CRYSTAL STRUCTURE OF P DOMAIN OF SNOW MOUNTAIN NOROVIRUS | VIRUS INTERNALIZATION, HBGA, VIRUS SURFACE, VIRAL PROTEIN
4rpb:B (GLU473) to (SER502) CRYSTAL STRUCTURE OF P DOMAIN OF SNOW MOUNTAIN NOROVIRUS | VIRUS INTERNALIZATION, HBGA, VIRUS SURFACE, VIRAL PROTEIN
4rpb:C (GLU473) to (SER502) CRYSTAL STRUCTURE OF P DOMAIN OF SNOW MOUNTAIN NOROVIRUS | VIRUS INTERNALIZATION, HBGA, VIRUS SURFACE, VIRAL PROTEIN
3cqz:K (LYS18) to (HIS40) CRYSTAL STRUCTURE OF 10 SUBUNIT RNA POLYMERASE II IN COMPLEX WITH THE INHIBITOR ALPHA-AMANITIN | TRANSCRIPTION-TOXIN COMPLEX, ALPHA AMANITIN, TOXIN, INHIBITOR, POLYMERASE, TRANSFERASE, DNA BINDING, ZINC-FINGER, PHOSPHOPROTEIN, TRANSCRIPTION
4rq7:A (GLY290) to (ASP314) HUMAN DNA POLYMERASE BETA WITH GAPPED DNA CONTAINING AN 8-OXO-7,8- DIHYDRO-GUANINE (8-OXOG)AND DATP SOAKED WITH MGCL2 FOR 1HR | X-FAMILY, POL BETA, TRANSFERASE-DNA COMPLEX
4rqy:A (VAL59) to (THR93) RE-REFINED STRUCTURE OF 1TE0 - STRUCTURAL ANALYSIS OF DEGS, A STRESS SENSOR OF THE BACTERIAL PERIPLASM | TWO DOMAINS, SERINE PROTEASE, PDZ, ALPHA-BETA PROTEIN, STRESS RESPONSE, HTRA, HYDROLASE
4rqy:B (VAL59) to (THR93) RE-REFINED STRUCTURE OF 1TE0 - STRUCTURAL ANALYSIS OF DEGS, A STRESS SENSOR OF THE BACTERIAL PERIPLASM | TWO DOMAINS, SERINE PROTEASE, PDZ, ALPHA-BETA PROTEIN, STRESS RESPONSE, HTRA, HYDROLASE
4rqz:A (ASN60) to (THR93) RE-REFINEMENT OF 1SOZ, CRYSTAL STRUCTURE OF DEGS PROTEASE IN COMPLEX WITH AN ACTIVATING PEPTIDE | STRESS RESPONSE, PROTEIN QUALITY CONTROL, PDZ, UPR, HTRA, HYDROLASE, HYDROLASE-PEPTIDE COMPLEX
4rqz:B (VAL59) to (THR93) RE-REFINEMENT OF 1SOZ, CRYSTAL STRUCTURE OF DEGS PROTEASE IN COMPLEX WITH AN ACTIVATING PEPTIDE | STRESS RESPONSE, PROTEIN QUALITY CONTROL, PDZ, UPR, HTRA, HYDROLASE, HYDROLASE-PEPTIDE COMPLEX
4rqz:B (VAL154) to (ASP193) RE-REFINEMENT OF 1SOZ, CRYSTAL STRUCTURE OF DEGS PROTEASE IN COMPLEX WITH AN ACTIVATING PEPTIDE | STRESS RESPONSE, PROTEIN QUALITY CONTROL, PDZ, UPR, HTRA, HYDROLASE, HYDROLASE-PEPTIDE COMPLEX
4rqz:C (GLN103) to (ALA134) RE-REFINEMENT OF 1SOZ, CRYSTAL STRUCTURE OF DEGS PROTEASE IN COMPLEX WITH AN ACTIVATING PEPTIDE | STRESS RESPONSE, PROTEIN QUALITY CONTROL, PDZ, UPR, HTRA, HYDROLASE, HYDROLASE-PEPTIDE COMPLEX
4rr0:A (VAL59) to (THR93) RE-REFINED 1VCW, CRYSTAL STRUCTURE OF DEGS AFTER BACKSOAKING THE ACTIVATING PEPTIDE | STRESS RESPONSE, PROTEIN QUALITY CONTROL, PDZ, UPR, HTRA, HYDROLASE
4rr0:B (VAL59) to (THR93) RE-REFINED 1VCW, CRYSTAL STRUCTURE OF DEGS AFTER BACKSOAKING THE ACTIVATING PEPTIDE | STRESS RESPONSE, PROTEIN QUALITY CONTROL, PDZ, UPR, HTRA, HYDROLASE
4rr1:A (VAL59) to (THR93) RE-REFINEMENT OF ENTRY 1SOT, CRYSTAL STRUCTURE OF THE DEGS STRESS SENSOR | STRESS RESPONSE, PROTEIN QUALITY CONTROL, PDZ, UPR, HTRA, HYDROLASE
4rr1:A (GLN103) to (ASN133) RE-REFINEMENT OF ENTRY 1SOT, CRYSTAL STRUCTURE OF THE DEGS STRESS SENSOR | STRESS RESPONSE, PROTEIN QUALITY CONTROL, PDZ, UPR, HTRA, HYDROLASE
4rr1:B (ASN60) to (THR93) RE-REFINEMENT OF ENTRY 1SOT, CRYSTAL STRUCTURE OF THE DEGS STRESS SENSOR | STRESS RESPONSE, PROTEIN QUALITY CONTROL, PDZ, UPR, HTRA, HYDROLASE
4rr1:C (ASN60) to (THR93) RE-REFINEMENT OF ENTRY 1SOT, CRYSTAL STRUCTURE OF THE DEGS STRESS SENSOR | STRESS RESPONSE, PROTEIN QUALITY CONTROL, PDZ, UPR, HTRA, HYDROLASE
4rr1:C (GLN103) to (ASN133) RE-REFINEMENT OF ENTRY 1SOT, CRYSTAL STRUCTURE OF THE DEGS STRESS SENSOR | STRESS RESPONSE, PROTEIN QUALITY CONTROL, PDZ, UPR, HTRA, HYDROLASE
3cs9:B (ASP241) to (THR272) HUMAN ABL KINASE IN COMPLEX WITH NILOTINIB | NILOTINIB, AMN107, KINASE, ABL, ALTERNATIVE SPLICING, ATP- BINDING, CELL ADHESION, CHROMOSOMAL REARRANGEMENT, CYTOPLASM, CYTOSKELETON, LIPOPROTEIN, MAGNESIUM, MANGANESE, METAL-BINDING, MYRISTATE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, PROTO-ONCOGENE, SH2 DOMAIN, SH3 DOMAIN, TRANSFERASE, TYROSINE-PROTEIN KINASE, ABL KINASE WT IN COMPLEX WITH NVP-AMN107
3nw8:C (ASP231) to (GLU275) GLYCOPROTEIN B FROM HERPES SIMPLEX VIRUS TYPE 1, Y179S MUTANT, HIGH-PH | ENVELOPE GLYCOPROTEIN, MEMBRANE FUSION, VIRAL PROTEIN, GLYCOPROTEIN B, HERPESVIRUS 1, HSV-1, MEMBRANE
4ch2:B (GLN335) to (LEU359) LOW-SALT CRYSTAL STRUCTURE OF A THROMBIN-GPIBALPHA PEPTIDE COMPLEX | HYDROLASE-PEPTIDE COMPLEX
4ch2:D (GLN335) to (LEU359) LOW-SALT CRYSTAL STRUCTURE OF A THROMBIN-GPIBALPHA PEPTIDE COMPLEX | HYDROLASE-PEPTIDE COMPLEX
4ch8:B (GLN335) to (LEU359) HIGH-SALT CRYSTAL STRUCTURE OF A THROMBIN-GPIBALPHA PEPTIDE COMPLEX | HYDROLASE-PEPTIDE COMPLEX, COMPLEX
4ch8:D (GLN335) to (THR360) HIGH-SALT CRYSTAL STRUCTURE OF A THROMBIN-GPIBALPHA PEPTIDE COMPLEX | HYDROLASE-PEPTIDE COMPLEX, COMPLEX
4ch8:F (GLN335) to (LEU359) HIGH-SALT CRYSTAL STRUCTURE OF A THROMBIN-GPIBALPHA PEPTIDE COMPLEX | HYDROLASE-PEPTIDE COMPLEX, COMPLEX
4ch8:H (GLN335) to (LEU359) HIGH-SALT CRYSTAL STRUCTURE OF A THROMBIN-GPIBALPHA PEPTIDE COMPLEX | HYDROLASE-PEPTIDE COMPLEX, COMPLEX
3nwa:A (VAL602) to (LEU625) GLYCOPROTEIN B FROM HERPES SIMPLEX VIRUS TYPE 1, W174R MUTANT, LOW-PH | COILED-COIL, ENVELOPE GLYCOPROTEIN, MEMBRANE FUSION, VIRAL PROTEIN, GLYCOPROTEIN B, HERPESVIRUS 1, HSV-1, MEMBRANE
3csy:K (TYR214) to (GLU245) CRYSTAL STRUCTURE OF THE TRIMERIC PREFUSION EBOLA VIRUS GLYCOPROTEIN IN COMPLEX WITH A NEUTRALIZING ANTIBODY FROM A HUMAN SURVIVOR | GLYCOPROTEIN-ANTIBODY COMPLEX, IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX
3csy:M (THR216) to (GLU245) CRYSTAL STRUCTURE OF THE TRIMERIC PREFUSION EBOLA VIRUS GLYCOPROTEIN IN COMPLEX WITH A NEUTRALIZING ANTIBODY FROM A HUMAN SURVIVOR | GLYCOPROTEIN-ANTIBODY COMPLEX, IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX
3csy:O (THR216) to (GLU245) CRYSTAL STRUCTURE OF THE TRIMERIC PREFUSION EBOLA VIRUS GLYCOPROTEIN IN COMPLEX WITH A NEUTRALIZING ANTIBODY FROM A HUMAN SURVIVOR | GLYCOPROTEIN-ANTIBODY COMPLEX, IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX
4rt5:A (SER82) to (ASP107) THE CRYSTAL STRUCTURE OF A GLYOXALASE/BLEOMYCIN RESISTANCE PROTEIN/DIOXYGENASE PROTEIN FROM PLANCTOMYCES LIMNOPHILUS DSM 3776 | OXIDOREDUCTASE, STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, A/B FOLD, CYTOSOLIC
4rt5:B (SER82) to (ASP107) THE CRYSTAL STRUCTURE OF A GLYOXALASE/BLEOMYCIN RESISTANCE PROTEIN/DIOXYGENASE PROTEIN FROM PLANCTOMYCES LIMNOPHILUS DSM 3776 | OXIDOREDUCTASE, STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, A/B FOLD, CYTOSOLIC
3nyn:B (THR185) to (GLU218) CRYSTAL STRUCTURE OF G PROTEIN-COUPLED RECEPTOR KINASE 6 IN COMPLEX WITH SANGIVAMYCIN | KINASE, GRK, RGS HOMOLOGY DOMAIN, G PROTEIN-COUPLED RECEPTOR KINASE, TRANSFERASE
3nyo:A (THR185) to (GLU218) CRYSTAL STRUCTURE OF G PROTEIN-COUPLED RECEPTOR KINASE 6 IN COMPLEX WITH AMP | KINASE, GRK, RGS HOMOLOGY DOMAIN, G PROTEIN-COUPLED RECEPTOR KINASE, TRANSFERASE
3nyo:B (THR185) to (GLU218) CRYSTAL STRUCTURE OF G PROTEIN-COUPLED RECEPTOR KINASE 6 IN COMPLEX WITH AMP | KINASE, GRK, RGS HOMOLOGY DOMAIN, G PROTEIN-COUPLED RECEPTOR KINASE, TRANSFERASE
5fww:A (LEU936) to (ILE961) WNT MODULATOR KREMEN IN COMPLEX WITH DKK1 (CRD2) AND LRP6 (PE3PE4) | SIGNALING PROTEIN, WNT, CELL SURFACE, SIGNALLING, MEMBRANE PROTEIN
3cw2:F (ARG384) to (VAL413) CRYSTAL STRUCTURE OF THE INTACT ARCHAEAL TRANSLATION INITIATION FACTOR 2 FROM SULFOLOBUS SOLFATARICUS . | AIF2, INTACT AIF2, INITIATION FACTOR 2 ALPHA SUBUNIT, INITIATION FACTOR 2 BETA SUBUNIT, INITIATION FACTOR 2 GAMMA SUBUNIT, INITIATION OF THE TRANSLATION, INITIATION FACTOR, PROTEIN BIOSYNTHESIS, RNA-BINDING, GTP-BINDING, NUCLEOTIDE- BINDING
3o5n:A (GLY657) to (GLU706) TETRAHYDROQUINOLINE CARBOXYLATES ARE POTENT INHIBITORS OF THE SHANK PDZ DOMAIN, A PUTATIVE TARGET IN AUTISM DISORDERS | PDZ DOMAIN, PROTEIN-PROTEIN INTERACTION, GKAP, POSTSYNAPTIC DENSITY, PROTEIN BINDING
5fzp:A (THR13) to (THR35) STRUCTURE OF THE DISPASE AUTOLYSIS INDUCING PROTEIN FROM STREPTOMYCES MOBARAENSIS | SIGNALING PROTEIN, DISPASE-AUTOLYSIS INDUCING PROTEIN, DAIP, GLUTAMINE CROSS- LINKING SITES, STREPTOMYCES MOBARAENSIS, 7-BLADED BETA-PROPELLER
3d26:A (ALA288) to (LEU323) NORWALK P DOMAIN A-TRISACCHARIDE COMPLEX | NORWALK P DOMAIN A TRISACCARIDE COMPLEX, VIRAL PROTEIN
3d26:B (LEU458) to (VAL484) NORWALK P DOMAIN A-TRISACCHARIDE COMPLEX | NORWALK P DOMAIN A TRISACCARIDE COMPLEX, VIRAL PROTEIN
3d2r:A (GLN345) to (PRO376) CRYSTAL STRUCTURE OF PYRUVATE DEHYDROGENASE KINASE ISOFORM 4 IN COMPLEX WITH ADP | PROTEIN-NUCLEOTIDE COMPLEX, HOMODIMER, GHKL SUPERFAMILY, KINASE, CARBOHYDRATE METABOLISM, GLUCOSE METABOLISM, MITOCHONDRION, PHOSPHOPROTEIN, TRANSFERASE, TRANSIT PEPTIDE
3d2r:B (GLN345) to (PRO376) CRYSTAL STRUCTURE OF PYRUVATE DEHYDROGENASE KINASE ISOFORM 4 IN COMPLEX WITH ADP | PROTEIN-NUCLEOTIDE COMPLEX, HOMODIMER, GHKL SUPERFAMILY, KINASE, CARBOHYDRATE METABOLISM, GLUCOSE METABOLISM, MITOCHONDRION, PHOSPHOPROTEIN, TRANSFERASE, TRANSIT PEPTIDE
3d49:H (GLN30) to (THR54) THROMBIN INHIBITION | BLOOD CLOTTING/HYDROLASE INHIBITOR, ACUTE PHASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, GAMMA- CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, KRINGLE, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, BLOOD CLOTTING-HYDROLASE INHIBITOR COMPLEX
4s2x:A (PRO10) to (PHE36) STRUCTURE OF E. COLI RPPH BOUND TO RNA AND TWO MAGNESIUM IONS | NUDIX HYDROLASE, RNA PYROPHOSPHOHYDROLASE, HYDROLASE-RNA COMPLEX
3o9b:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD25 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3o9l:C (SER8) to (THR39) DESIGN AND OPTIMISATION OF NEW PIPERIDINES AS RENIN INHIBITORS | HYDROLASE, PROTEASE, GLYCOSILATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4cr5:A (GLN30) to (THR54) CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD GENERATION AND STRUCTURE AIDED DRUG DESIGN | HYDROLASE
4cr9:A (GLN30) to (THR54) CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD GENERATION AND STRUCTURE AIDED DRUG DESIGN | HYDROLASE
4crf:A (GLN30) to (THR54) CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD GENERATION AND STRUCTURE AIDED DRUG DESIGN | HYDROLASE
4crg:A (GLN30) to (THR54) CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD GENERATION AND STRUCTURE AIDED DRUG DESIGN | HYDROLASE
3d6e:B (HIS25) to (GLN55) CRYSTAL STRUCTURE OF THE ENGINEERED 1,3-1,4-BETA-GLUCANASE PROTEIN FROM BACILLUS LICHENIFORMIS | BETA-GLUCAN HYDROLYSIS, CALCIUM BINDING MOTIF, PROTEIN ENGINEERING, GLYCOSIDASE, HYDROLASE
3d6h:A (SER236) to (LEU258) CRYSTAL STRUCTURE OF HUMAN CASPASE-1 WITH A NATURALLY-OCCURRING ASN263->SER SUBSTITUTION IN COMPLEX WITH 3-[2-(2- BENZYLOXYCARBONYLAMINO-3-METHYL-BUTYRYLAMINO)-PROPIONYLAMINO]-4-OXO- PENTANOIC ACID (Z-VAD-FMK) | CATALYTIC DOMAIN, NATURALLY-OCCURRING MUTATION, APOPTOSIS, HYDROLASE, PROTEASE, THIOL PROTEASE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3d9v:A (GLY193) to (ASP232) CRYSTAL STRUCTURE OF ROCK I BOUND TO H-1152P A DI- METHYLATED VARIANT OF FASUDIL | DIMER, DIMERIZATION, KINASE, PHOSPHORYLATION, FASUDIL, APOPTOSIS, ATP-BINDING, COILED COIL, CYTOPLASM, GOLGI APPARATUS, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PHORBOL-ESTER BINDING, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, ZINC, ZINC- FINGER
3oc5:A (ASP228) to (ASN274) CRYSTAL STRUCTURE OF THE VIBRIO CHOLERAE SECRETED COLONIZATION FACTOR TCPF | MULTIDOMAIN PROTEIN, IMMUNOGLOBULIN-LIKE (IG-LIKE) FOLD, CELL ADHESION
3odk:A (PRO9) to (TRP34) DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION | SBDD, PPIASE, ISOMERASE, ROTAMASE, SMALL MOLECULE, PROLINE DIRECTED KINASE, CELL CYCLE, ONCOGENIC TRANSFORMATION, NUCLEUS, PHOSPHOPROTEIN
3oe7:W (ASN35) to (ASP65) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: GAMMA-I270T | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, ADP, PO4, MITOCHONDRIA, HYDROLASE
3oee:E (ASN35) to (ASP65) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: ALPHA-F405S | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, HYDROLASE, ADP, PO4, MITOCHONDRIA
4cxx:A (SER95) to (PRO119) CRYSTAL STRUCTURE OF HUMAN FTO IN COMPLEX WITH ACYLHYDRAZINE INHIBITOR 16 | OXIDOREDUCTASE, SMALL MOLECULAR PROBE
4cyi:E (GLY243) to (LYS275) CHAETOMIUM THERMOPHILUM PAN3 | TRANSFERASE
4tq7:A (PRO122) to (ILE151) N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P Q93E (NN10) | CENTRIOLE SAS-6, CARTWHEEL, STRUCTURAL PROTEIN, BETA-SANDWICH, ALPHA- BETA PROTEIN, CENTRIOLAR
3ogg:A (ASN894) to (ASN919) CRYSTAL STRUCTURE OF THE RECEPTOR BINDING DOMAIN OF BOTULINUM NEUROTOXIN D | BOTULINUM NEUROTOXIN, SEROTYPE D, RECEPTOR BINDING DOMAIN, JELLY ROLL TREFOIL FOLD, RECEPTOR BINDING, GANGLIOSIDES, MEMBRANE TO CYTOPLASM, TOXIN
4d05:A (ILE29) to (PRO49) STRUCTURE AND ACTIVITY OF A MINIMAL-TYPE ATP-DEPENDENT DNA LIGASE FROM A PSYCHROTOLERNT BACTERIUM | LIGASE
5gib:A (GLN15) to (SER37) SUCCINIC ACID BOUND TRYPSIN CRYSTALLIZED AS DIMER | TRYPSIN, DIMER, SUCCINIC ACID, HYDROLASE
4d0y:A (GLU56) to (ASN77) CRYSTAL STRUCTURE OF DACB FROM STREPTOCOCCUS PNEUMONIAE D39 | HYDROLASE, L-D-CARBOXIPEPTIDASE, PNEUMOCOCCUS
4d0y:B (GLU56) to (ASN77) CRYSTAL STRUCTURE OF DACB FROM STREPTOCOCCUS PNEUMONIAE D39 | HYDROLASE, L-D-CARBOXIPEPTIDASE, PNEUMOCOCCUS
3dj1:A (PHE31) to (GLN79) CRYSTAL STRUCTURE OF TIP-1 WILD TYPE | TAX-INTERACTING PROTEIN-1, PDZ DOMAIN, TIP-1, CYTOPLASM, NUCLEUS, WNT SIGNALING PATHWAY, SIGNALING PROTEIN
3dj1:B (GLY30) to (GLN79) CRYSTAL STRUCTURE OF TIP-1 WILD TYPE | TAX-INTERACTING PROTEIN-1, PDZ DOMAIN, TIP-1, CYTOPLASM, NUCLEUS, WNT SIGNALING PATHWAY, SIGNALING PROTEIN
5gkj:A (GLY149) to (ARG182) STRUCTURE OF ENDOMS IN APO FORM | ENDONUCLEASE, DNA-BINDING, HYDROLASE
3dj7:A (ASP145) to (PHE178) CRYSTAL STRUCTURE OF THE MOUSE AURORA-A CATALYTIC DOMAIN (ASN186->GLY, LYS240->ARG, MET302->LEU) IN COMPLEX WITH COMPOUND 130. | AURORA A, SMALL-MOLECULE INHIBITOR, FRAGMENT-BASED DRUG DISCOVERY, KINASE, TRANSFERASE
4ttx:B (PRO122) to (ILE151) N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P VARIANT G94C K146C (NN19) | HOMODIMER, STABILIZATION, MUTATION, CENTRIOLE SAS-6, CARTWHEEL, STRUCTURAL PROTEIN, BETA-SANDWICH, ALPHA-BETA PROTEIN, CENTRIOLAR
4ttx:D (PRO122) to (ILE151) N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P VARIANT G94C K146C (NN19) | HOMODIMER, STABILIZATION, MUTATION, CENTRIOLE SAS-6, CARTWHEEL, STRUCTURAL PROTEIN, BETA-SANDWICH, ALPHA-BETA PROTEIN, CENTRIOLAR
4ttx:E (PRO122) to (ILE151) N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P VARIANT G94C K146C (NN19) | HOMODIMER, STABILIZATION, MUTATION, CENTRIOLE SAS-6, CARTWHEEL, STRUCTURAL PROTEIN, BETA-SANDWICH, ALPHA-BETA PROTEIN, CENTRIOLAR
4tty:A (PRO122) to (ILE151) N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P G94D F145W Q147R (NN25) | CENTRIOLE SAS-6, CARTWHEEL, STRUCTURAL PROTEIN, BETA-SANDWICH, ALPHA- BETA PROTEIN
4ttz:D (ARG123) to (ILE151) N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P VARIANT G94E F145W Q147K (NN26) | STABILIZATION, CENTRIOLE SAS-6, CARTWHEEL, STRUCTURAL PROTEIN, BETA- SANDWICH, ALPHA-BETA PROTEIN, CENTRIOLAR
3dko:A (CYS632) to (LEU667) COMPLEX BETWEEN THE KINASE DOMAIN OF HUMAN EPHRIN TYPE-A RECEPTOR 7 (EPHA7) AND INHIBITOR ALW-II-49-7 | ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, RECEPTOR, SIGNAL, TRANSFERASE, PHOSPHORYLATION, TRANSMEMBRANE, TYROSINE- PROTEIN KINASE, ALTERNATIVE SPLICING, GLYCOPROTEIN, INHIBITOR, STRUCTURAL GENOMICS CONSORTIUM, SGC, MEMBRANE, PHOSPHOPROTEIN, POLYMORPHISM, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES
4tvc:A (PHE1806) to (PRO1827) N-TERMINALLY TRUNCATED DEXTRANSUCRASE DSR-E FROM LEUCONOSTOC MESENTEROIDES NRRL B-1299 IN COMPLEX WITH GLUCO-OLIGOSACCHARIDES | ALPHA-1, 2-BRANCHING-SUCRASE, GLUCAN BINDING DOMAIN, GLUCO- OLIGOSACCHARIDES, GLUCANSUCRASE, TRANSFERASE
4tvz:B (GLU264) to (VAL297) CRYSTAL STRUCTURE OF SCARB2 IN NEURAL CONDITION (PH7.5) | LIPID BINDING TUNNEL, PROTEIN BINDING
3dls:B (MET1002) to (LYS1031) CRYSTAL STRUCTURE OF HUMAN PAS KINASE BOUND TO ADP | PAS KINASE, PASK, PROTEIN KINASE, DRUG DISCOVERY, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
4txg:A (GLN556) to (GLU582) CRYSTAL STRUCTURE OF A FAMILY GH18 CHITINASE FROM CHROMOBACTERIUM VIOLACEUM | CHITINASE FAMILY GH18 CHITINASE, HYDROLASE
4d4y:A (ARG421) to (CYS456) FOCAL ADHESION KINASE CATALYTIC DOMAIN | TRANSFERASE, KINASE INHIBITOR, ATP-BINDING, INTEGRIN SIGNALING
4d58:A (ARG421) to (ASN458) FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH BIS- ANILINO PYRIMIDINE INHIBITOR | TRANSFERASE, KINASE INHIBITOR, ATP-BINDING, INTEGRIN SIGNALING
4d5h:A (ARG421) to (CYS456) FOCAL ADHESION KINASE CATALYTIC DOMAIN | TRANSFERASE, KINASE INHIBITOR, ATP-BINDING, INTEGRIN SIGNALING
3ony:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH FUCOSE | CAPSID PROTEIN, VIRAL PROTEIN
3ony:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH FUCOSE | CAPSID PROTEIN, VIRAL PROTEIN
3ony:C (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH FUCOSE | CAPSID PROTEIN, VIRAL PROTEIN
3dos:D (ASN157) to (GLY180) CRYSTAL STRUCTURE OF THE COMPLEX OF THE CAF1M CHAPERONE WITH THE MINI-FIBER OF TWO CAF1 SUBUNITS (CAF1:CAF1), CARRYING THE THR7PHE AND ALA9VAL MUTATIONS IN THE GD DONOR STRAND | BETA BARREL, PROTEIN-PROTEIN COMPLEX, DONOR STRAND COMPLEMENTATION, CHAPERONE, IMMUNOGLOBULIN DOMAIN, PERIPLASM, PLASMID, CAPSULE, SECRETED, CHAPERONE/STRUCTURAL PROTEIN COMPLEX
5gxp:B (GLN30) to (SER54) CATIONIC TRYPSIN WITH GOL/PGE AS DIMER AT PH 4.6 | CATIONIC TRYPSIN, GOL, PGE, HYDROLASE
4tz5:A (ILE497) to (GLY537) ENSEMBLE REFINEMENT OF THE E502A VARIANT OF SACTELAM55A FROM STREPTOMYCES SP. SIREXAA-E IN COMPLEX WITH LAMINARIHEXAOSE | EXO-BETA-1, 3-GLUCANASE, BETA-1, GH55, LAMINARITETRAOSE, SECRETED, BIOMASS DEGRADATION, HYDROLASE
5h2g:A (SER141) to (PRO167) CRYSTAL STRCUTURE OF OXIDIZED DAPF FROM CORYNEBACTERIUM GLUTAMICUM | ISOMERASE
5h2y:B (SER141) to (PRO167) CRYSTAL STRCUTURE OF REDUCED DAPF FROM CORYNEBACTERIUM GLUTAMICUM | ISOMERASE
4d8e:A (HIS340) to (ARG368) HIGH RESOLUTION STRUCTURES OF MONOMERIC S. PYOGENES SPEB REVEALS ROLE OF GLYCINE-RICH ACTIVE SITE LOOP | PAPAIN FOLD, CYSTEINE PROTEASE, E64 COMPLEX, SECRETED, HYDROLASE
3dri:A (GLY392) to (ALA414) CRYSTAL STRUCTURE OF LACTOCOCCAL OPPA CO-CRYSTALLIZED WITH AN OCTAMER PEPTIDE IN AN OPEN CONFORMATION | OLIGO-PEPTIDE BINDING, VOLUMINOUS BINDING CAVITY, VENUS FLY-TRAP, PEPTIDE BINDING PROTEIN
4d94:A (PHE224) to (GLY257) CRYSTAL STRUCTURE OF TEP1R | PLASMODIUM REFRACTORY ALLELE, IMMUNE SYSTEM, FULL-LENGTH PROTEIN, THIOESTER, MACROGLOBULIN DOMAINS, COMPONENT OF INNATE IMMUNE RESPONSE BY THE OPSINIZATION AND MELANIZATION OF PATHOGENS
3dsn:A (ASN157) to (GLY180) CRYSTAL STRUCTURE OF THE COMPLEX OF THE CAF1M CHAPERONE WITH THE MINI-FIBER OF TWO CAF1 SUBUNITS (CAF1:CAF1), CARRYING THE THR7PHE MUTATION IN THE GD DONOR STRAND | CHAPERONE, FIMBRIAL SUBUNIT, FIMBRIAE, DONOR STRAND COMPLEMENTATION, PROTEIN-PROTEIN COMPLEX, BETA BARREL, IMMUNOGLOBULIN DOMAIN, PERIPLASM, PLASMID, CAPSULE, SECRETED
4d9r:B (MET30) to (LEU53) INHIBITING ALTERNATIVE PATHWAY COMPLEMENT ACTIVATION BY TARGETING THE EXOSITE ON FACTOR D | FACTOR D, COMPLEMENT, ANTIBODY, EXOSITE, FAB, CHYMOTRYPSIN, PROTEASE, HYDROLASE-IMMUNE SYSTEM COMPLEX
4da2:A (GLY101) to (SER133) THE STRUCTURE OF PYROCOCCUS FURIOSUS SFSA IN COMPLEX WITH CA2+ | OB FOLD, PD-(D/E)XK DOMAIN, NUCLEASE, DNA BINDING PROTEIN
4da2:B (GLY52) to (ILE78) THE STRUCTURE OF PYROCOCCUS FURIOSUS SFSA IN COMPLEX WITH CA2+ | OB FOLD, PD-(D/E)XK DOMAIN, NUCLEASE, DNA BINDING PROTEIN
4dav:A (ARG50) to (ILE78) THE STRUCTURE OF PYROCOCCUS FURIOSUS SFSA IN COMPLEX WITH DNA | OB FOLD, PD-(D/E)XK DOMAIN, NUCLEASE, PROTEIN-DNA COMPLEX, HYDROLASE- DNA COMPLEX
4dav:B (ARG50) to (ILE78) THE STRUCTURE OF PYROCOCCUS FURIOSUS SFSA IN COMPLEX WITH DNA | OB FOLD, PD-(D/E)XK DOMAIN, NUCLEASE, PROTEIN-DNA COMPLEX, HYDROLASE- DNA COMPLEX
3oty:B (ARG41) to (GLY78) MDR769 HIV-1 PROTEASE COMPLEXED WITH RT/RH HEPTA-PEPTIDE | MDR HIV-1 PROTEASE, INHIBITOR, DRUG RESISTANCE, SUBSTRATE ENVELOPE, HIV-1 PROTEASE, PROTEASE, SUBSTRATE PEPTIDE, HYDROLASE, HYDROLASE- PEPTIDE COMPLEX
3oua:A (GLY40) to (GLY78) MDR769 HIV-1 PROTEASE COMPLEXED WITH P1/P6 HEPTA-PEPTIDE | MDR HIV-1 PROTEASE, INHIBITOR, DRUG RESISTANCE, SUBSTRATE ENVELOPE, HIV-1 PROTEASE, PROTEASE, P1/P6 SUBSTRATE PEPTIDE, NONE, HYDROLASE, HYDROLASE-PEPTIDE COMPLEX
3oua:B (GLY40) to (GLY78) MDR769 HIV-1 PROTEASE COMPLEXED WITH P1/P6 HEPTA-PEPTIDE | MDR HIV-1 PROTEASE, INHIBITOR, DRUG RESISTANCE, SUBSTRATE ENVELOPE, HIV-1 PROTEASE, PROTEASE, P1/P6 SUBSTRATE PEPTIDE, NONE, HYDROLASE, HYDROLASE-PEPTIDE COMPLEX
4u3y:B (ILE24) to (ASP57) APO MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 4 (MAP4K4) | KINASE, TRANSFERASE
4u41:B (PHE25) to (ASP57) MAP4K4 BOUND TO INHIBITOR COMPOUND 1 | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4u43:B (ILE24) to (ASP57) MAP4K4 IN COMPLEX WITH INHIBITOR (COMPOUND 6) | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4u44:B (ILE24) to (ASP57) MAP4K4 IN COMPLEX WITH INHIBITOR (COMPOUND 16) | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5hdc:A (GLU93) to (ARG124) FEMTOSECOND STRUCTURAL DYNAMICS DRIVES THE TRANS/CIS ISOMERIZATION IN PHOTOACTIVE YELLOW PROTEIN: 100 FS TO 400 FS STRUCTURE | PHOTORECEPTOR CIS TRANS ISOMERIZATION, TRANS CIS ISOMERIZATION, FREE ELECTRON LASER, SIGNALING PROTEIN
5hed:A (PHE325) to (SER361) THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A MUTANT C-TERMINAL PEPTIDE DERIVED FROM CRIPT (T-2F) | PDZ, GLGF, DHR, ADHESION, SYNAPSE, SYNAPTIC DENSITY, PEPTIDE-BINDING DOMAIN, PEPTIDE BINDING PROTEIN
3oxx:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 I50V, A71V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR ATAZANAVIR | HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3oxz:A (ASP241) to (THR272) CRYSTAL STRUCTURE OF ABL KINASE DOMAIN BOUND WITH A DFG-OUT INHIBITOR AP24534 | PROTEIN-INHIBITOR COMPLEX, PROTEIN KINASE TWO-DOMAIN FOLD, PHOSPHOTRANSFERASE, ATP BINDING, PHOSPHORYLATION, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
5hf1:A (PHE325) to (SER361) THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 (G330T MUTANT) IN COMPLEX WITH A MUTANT C-TERMINAL PEPTIDE DERIVED FROM CRIPT (T-2F) | PDZ, GLGF, DHR, ADHESION, SYNAPSE, SYNAPTIC DENSITY, PEPTIDE-BINDING DOMAIN, PEPTIDE BINDING PROTEIN
5hfb:A (PHE325) to (SER361) THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 (H372A MUTANT) IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT | PDZ, GLGF, DHR, ADHESION, SYNAPSE, SYNAPTIC DENSITY, PEPTIDE-BINDING DOMAIN, PEPTIDE BINDING PROTEIN
5hfc:A (PHE325) to (SER361) THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 (H372A MUTANT) IN COMPLEX WITH A MUTANT C-TERMINAL PEPTIDE DERIVED FROM CRIPT (T-2F) | PDZ, GLGF, DHR, ADHESION, SYNAPSE, SYNAPTIC DENSITY, PEPTIDE-BINDING DOMAIN, PEPTIDE BINDING PROTEIN
4dgj:A (VAL15) to (SER38) STRUCTURE OF A HUMAN ENTEROPEPTIDASE LIGHT CHAIN VARIANT | SERINE PROTEASE, HYDROLASE
4dgj:B (VAL15) to (SER38) STRUCTURE OF A HUMAN ENTEROPEPTIDASE LIGHT CHAIN VARIANT | SERINE PROTEASE, HYDROLASE
4dgj:D (VAL16) to (SER38) STRUCTURE OF A HUMAN ENTEROPEPTIDASE LIGHT CHAIN VARIANT | SERINE PROTEASE, HYDROLASE
3dy5:A (LEU190) to (LYS222) ALLENE OXIDE SYNTHASE 8R-LIPOXYGENASE FROM PLEXAURA HOMOMALLA | FUSION PROTEIN, BI-FUNCTIONAL ENZYME, DIOXYGENASE, FATTY ACID BIOSYNTHESIS, HEME, IRON, LIPID SYNTHESIS, LYASE, MEMBRANE, METAL- BINDING, MULTIFUNCTIONAL ENZYME, OXIDOREDUCTASE, OXYLIPIN BIOSYNTHESIS
5hj1:A (SER198) to (ALA235) CRYSTAL STRUCTURE OF PDZ DOMAIN OF PULLULANASE C PROTEIN OF TYPE II SECRETION SYSTEM FROM KLEBSIELLA PNEUMONIAE IN COMPLEX WITH FATTY ACID | GSPC PROTEIN, STRUCTURAL GENOMICS, CSGID, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, HYDROLASE
3p17:H (GLN30) to (THR54) THROMBIN INHIBITION BY PYRIDIN DERIVATIVES | SERINE PROTEASE, KRINGLE, DISULFIDE BONDS, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, THROMBIN INHIBITOR, GLYCOSYLATION, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4djm:B (VAL163) to (SER185) CRYSTAL STRUCTURE OF THE E. COLI CHAPERONE DRAB | DRAB, CHAPERONE, PILI
4dks:A (ASP225) to (HIS250) A SPINDLE-SHAPED VIRUS PROTEIN (CHYMOTRYPSIN TREATED) | CATALYTIC DOMAIN, INTEGRASE, THE C174 DOMAIN OF SSV1 INT, SEVEN- HELICES, THREE-STRANDED ANTIPARALLEL-SHEET', RECOMBINATION
4u85:A (PRO9) to (TRP34) HUMAN PIN1 WITH CYSTEINE SULFINIC ACID 113 | PIN1 OXIDATION ISOMERASE
4dm2:A (GLY38) to (GLY70) CONTRIBUTION OF DISULFIDE BOND TOWARD THERMOSTABILITY IN HYPERTHERMOSTABLE ENDOCELLULASE | TIM BARREL, GLYCOSYL HYDROLASE, MEMBRANE-BOUND, HYDROLASE
5hma:A (GLU79) to (GLN112) CRYSTAL STRUCTURE OF MAMO PROTEASE DOMAIN FROM MAGNETOSPIRILLUM MAGNETICUM (NI BOUND FORM) | TRYPSIN, BIOMINERALIZATION, PSEUDO-PROTEASE, MAGNETOSOME, HYDROLASE
3e0j:A (THR96) to (GLY146) X-RAY STRUCTURE OF THE COMPLEX OF REGULATORY SUBUNITS OF HUMAN DNA POLYMERASE DELTA | DNA POLYMERASE DELTA, P66 SUBUNIT, P50 SUBUNIT, HUMAN, DNA REPLICATION, DNA-DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, POLYMORPHISM, TRANSFERASE, PHOSPHOPROTEIN
3e0j:C (THR96) to (GLY146) X-RAY STRUCTURE OF THE COMPLEX OF REGULATORY SUBUNITS OF HUMAN DNA POLYMERASE DELTA | DNA POLYMERASE DELTA, P66 SUBUNIT, P50 SUBUNIT, HUMAN, DNA REPLICATION, DNA-DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, POLYMORPHISM, TRANSFERASE, PHOSPHOPROTEIN
3e0j:E (THR96) to (GLY146) X-RAY STRUCTURE OF THE COMPLEX OF REGULATORY SUBUNITS OF HUMAN DNA POLYMERASE DELTA | DNA POLYMERASE DELTA, P66 SUBUNIT, P50 SUBUNIT, HUMAN, DNA REPLICATION, DNA-DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, POLYMORPHISM, TRANSFERASE, PHOSPHOPROTEIN
3e0j:G (THR96) to (GLY146) X-RAY STRUCTURE OF THE COMPLEX OF REGULATORY SUBUNITS OF HUMAN DNA POLYMERASE DELTA | DNA POLYMERASE DELTA, P66 SUBUNIT, P50 SUBUNIT, HUMAN, DNA REPLICATION, DNA-DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, POLYMORPHISM, TRANSFERASE, PHOSPHOPROTEIN
3e0n:B (GLN30) to (LEU53) THE X-RAY STRUCTURE OF HUMAN PROSTASIN IN COMPLEX WITH DFFR- CHLOROMETHYL KETONE INHIBITOR | PROSTASIN, PROTEASE, CHLOROMETHYL-KETONE, CHANNEL, ENAC, CELL MEMBRANE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, SECRETED, SERINE PROTEASE, TRANSMEMBRANE, ZYMOGEN
3p5k:A (THR7) to (GLY31) P38 INHIBITOR-BOUND | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3e0v:A (ASN139) to (ASN167) CRYSTAL STRUCTURE OF PYRUVATE KINASE FROM LEISHMANIA MEXICANA IN COMPLEX WITH SULPHATE IONS | PYRUVATE, KINASE, NAD+ NADH, ADP, PHOSPHOENOLPYRUVATE, PEP, GLYCOLYSIS, TRYPANOSOMATID, LEISHMANIA, MEXICANA, ALLOSTERIC ENZYME, MAGNESIUM, METAL-BINDING, TRANSFERASE
4u8t:D (GLY220) to (ILE269) CRYSTAL STRUCTURE OF YTH DOMAIN OF ZYGOSACCHAROMYCES ROUXII MRB1 PROTEIN IN COMPLEX WITH N6-METHYLADENOSINE RNA | N6-METHYLADENOSINE RNA, YTH RNA BINDING DOMAIN, RNA BINDING PROTEIN- RNA COMPLEX
5hmq:B (ALA467) to (LEU495) XYLOSE ISOMERASE-LIKE TIM BARREL/4-HYDROXYPHENYLPYRUVATE DIOXYGENASE FUSION PROTEIN | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE, XYLOSE ISOMERASE-LIKE TIM BARREL, OXIDOREDUCTASE, LYASE
5hp5:A (ASN38) to (LYS65) SRTUCTURE OF HUMAN PEPTIDYLARGININE DEIMINASE TYPE I (PAD1) | PEPTIDYLARGININE DEIMINASE, PAD1, ISOZYME, MONOMER, HYDROLASE
5hp5:A (ASP75) to (ASP122) SRTUCTURE OF HUMAN PEPTIDYLARGININE DEIMINASE TYPE I (PAD1) | PEPTIDYLARGININE DEIMINASE, PAD1, ISOZYME, MONOMER, HYDROLASE
5hp5:B (ASN38) to (GLY64) SRTUCTURE OF HUMAN PEPTIDYLARGININE DEIMINASE TYPE I (PAD1) | PEPTIDYLARGININE DEIMINASE, PAD1, ISOZYME, MONOMER, HYDROLASE
5hp5:B (ASP75) to (ASP122) SRTUCTURE OF HUMAN PEPTIDYLARGININE DEIMINASE TYPE I (PAD1) | PEPTIDYLARGININE DEIMINASE, PAD1, ISOZYME, MONOMER, HYDROLASE
4doq:C (GLN30) to (SER54) CRYSTAL STRUCTURE OF THE COMPLEX OF PORCINE PANCREATIC TRYPSIN WITH 1/2SLPI | BETA BARREL, MAINLY BATA, PROTEASE, PROTEASE INHIBITOR, SECRETORY LEUKOCYTE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3p8g:A (GLN30) to (SER54) CRYSTAL STRUCTURE OF MT-SP1 IN COMPLEX WITH BENZAMIDINE | HYDROLASE
3p92:A (GLN30) to (SER54) HUMAN MESOTRYPSIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR VARIANT (BPTI-K15R/R17G) | MESOTRYPSIN, TRYPSIN IV, CANONICAL INHIBITOR, BOVINE PANCREATIC TRYPSIN INIBITOR, BPTI, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4dqy:B (GLN301) to (GLN326) STRUCTURE OF HUMAN PARP-1 BOUND TO A DNA DOUBLE STRAND BREAK | PARP, POLY(ADP-RIBOSE) POLYMERASE, DNA BINDING PROTEIN, ADP-RIBOSYL TRANSFERASE, PARP-LIKE ZINC FINGER, POLY(ADP-RIBOSYL)ATION, DNA DAMAGE DETECTION, TRANSFERASE-DNA COMPLEX
4dqy:E (GLN301) to (GLN326) STRUCTURE OF HUMAN PARP-1 BOUND TO A DNA DOUBLE STRAND BREAK | PARP, POLY(ADP-RIBOSE) POLYMERASE, DNA BINDING PROTEIN, ADP-RIBOSYL TRANSFERASE, PARP-LIKE ZINC FINGER, POLY(ADP-RIBOSYL)ATION, DNA DAMAGE DETECTION, TRANSFERASE-DNA COMPLEX
3pa1:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH HBGA TYPE A | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
3pa1:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH HBGA TYPE A | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
4ubg:A (ARG57) to (SER84) RESTING STATE OF RAT CYSTEINE DIOXYGENASE C93G VARIANT | CYSTEINE DIOXYGENASE, NON-HEME MONO-IRON, CUPIN, CYSTEINE TO GLYCINE SUBSTITUTION, OXIDOREDUCTASE
4ubh:A (ARG57) to (SER84) RESTING STATE OF RAT CYSTEINE DIOXYGENASE Y157F VARIANT | CYSTEINE DIOXYGENASE, NON-HEME MONO-IRON, CUPIN, TYROSINE TO PHENYLALANINE SUBSTITUTION, OXIDOREDUCTASE
3pa8:B (TYR199) to (LYS221) STRUCTURE OF THE C. DIFFICILE TCDB CYSTEINE PROTEASE DOMAIN IN COMPLEX WITH A PEPTIDE INHIBITOR | CLAN CD CYSTEINE PROTEASE, PROTEASE, TOXIN, TOXIN-PEPTIDE INHIBITOR COMPLEX
5hu6:C (ALA177) to (LEU198) STRUCTURE OF THE T. BRUCEI HAPTOGLOBIN-HAEMOGLOBIN RECEPTOR BOUND TO HUMAN HAPTOLGOBIN-HAEMOGLOBIN | TRYPANOSOME HAPTOGLOBIN-HAEMOGLOBIN, TRANSPORT PROTEIN
5hvy:A (LEU19) to (GLN53) CDK8/CYCC IN COMPLEX WITH COMPOUND 20 | TRANSFERASE-TRANSCRIPTION COMPLEX
4dt7:B (GLN30) to (THR54) CRYSTAL STRUCTURE OF THROMBIN BOUND TO THE ACTIVATION DOMAIN QEDQVDPRLIDGKMTRRGDS OF PROTEIN C | SERINE PROTEASE, HYDROLASE
4ud9:H (GLN30) to (THR54) THROMBIN IN COMPLEX WITH 5-CHLOROTHIOPHENE-2-CARBOXAMIDE | HYDROLASE, HYDROLASE INHIBITOR COMPLEX, SERINE PROTEASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, BLOOD CLOTTING INHIBITOR, THROMBIN INHIBITOR, FRAGMENT, GLYCOSYLATION, BLOOD
4udw:H (GLN30) to (THR54) THROMBIN IN COMPLEX WITH 1-(2R)-2-AMINO-3-PHENYL-PROPANOYL- N-(2,5DICHLOROPHENYL)METHYLPYRROLIDINE-2-CARBOXAMIDE | HYDROLASE, HYDROLASE INHIBITOR COMPLEX, SERINE PROTEASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, BLOOD CLOTTING INHIBITOR, THROMBIN INHIBITOR, FRAGMENT, GLYCOSYLATION, BLOOD
4ue7:H (GLN30) to (THR54) THROMBIN IN COMPLEX WITH 1-AMIDINOPIPERIDINE | HYDROLASE, HYDROLASE INHIBITOR COMPLEX, SERINE PROTEASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, BLOOD CLOTTING INHIBITOR, THROMBIN INHIBITOR, GLYCOSYLATION, BLOOD
4ueu:A (GLU7) to (GLY42) TYROSINE KINASE AS - A COMMON ANCESTOR OF SRC AND ABL | TRANSFERASE, ANCESTOR PROTEIN, AMPPCP, DFG-IN
5hza:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 3-FUCOSYLLACTOSE (3 FL) | NOROVIRUS, P DOMAIN, HMO, 3-FUCOSYLLACTOSE, HUMAN MILK, VIRUS, VIRAL PROTEIN
5hza:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 3-FUCOSYLLACTOSE (3 FL) | NOROVIRUS, P DOMAIN, HMO, 3-FUCOSYLLACTOSE, HUMAN MILK, VIRUS, VIRAL PROTEIN
5hzb:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 2-FUCOSYLLACTOSE (2'FL) | NOROVIRUS CAPSID, P DOMAIN, HMO, HUMAN MILK, 2-FUCOSYLLACTOSE, VIRUS, VIRAL PROTEIN
5hzb:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 2-FUCOSYLLACTOSE (2'FL) | NOROVIRUS CAPSID, P DOMAIN, HMO, HUMAN MILK, 2-FUCOSYLLACTOSE, VIRUS, VIRAL PROTEIN
3pee:B (TYR199) to (LYS221) STRUCTURE OF THE C. DIFFICILE TCDB CYSTEINE PROTEASE DOMAIN | CLAN CD CYSTEINE PROTEASE, PROTEASE, INOSITOL HEXAKISPHOSPHATE, TOXIN
4ufe:H (GLN30) to (THR54) THROMBIN IN COMPLEX WITH (2R)-2-(BENZYLSULFONYLAMINO)-N-(2-( (4-CARBAMIMIDOYLPHENYL)METHYLAMINO)-2-OXO-BUTYL)-3-PHENYL- PROPANAMIDE | HYDROLASE, HYDROLASE INHIBITOR COMPLEX, SERINE PROTEASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, BLOOD CLOTTING INHIBITOR, THROMBIN INHIBITOR, PREORGANIZATION, GLYCOSYLATION, BLOOD
3pfm:A (GLN427) to (ALA461) CRYSTAL STRUCTURE OF A EAL DOMAIN OF GGDEF DOMAIN PROTEIN FROM PSEUDOMONAS FLUORESCENS PF | PSI2, MCSG, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, EAL DOMAIN, SIGNALING PROTEIN
4dvk:A (ASN145) to (PHE159) CRYSTAL STRUCTURE OF THE GLYCOPROTEIN ERNS FROM THE PESTIVIRUS BVDV-1 STRAIN NCP-7 | T2 RIBONUCLEASE, VIRUS ENVELOPE GLYCOPROTEIN, VIRAL PROTEIN
4dvk:B (ASN145) to (PHE159) CRYSTAL STRUCTURE OF THE GLYCOPROTEIN ERNS FROM THE PESTIVIRUS BVDV-1 STRAIN NCP-7 | T2 RIBONUCLEASE, VIRUS ENVELOPE GLYCOPROTEIN, VIRAL PROTEIN
4dw2:U (PHE30) to (SER54) THE CRYSTAL STRUCTURE OF UPA IN COMPLEX WITH THE FAB FRAGMENT OF MAB- 112 | UROKINASE-TYPE PLASMINOGEN ACTIVATOR, ANTIBODY, SERINE PROTEASE, ZYMOGEN, HYDROLASE-IMMUNE SYSTEM COMPLEX
4dwh:A (LYS130) to (GLU154) STRUCTURE OF THE MAJOR TYPE 1 PILUS SUBUNIT FIMA BOUND TO THE FIMC (2.5 A RESOLUTION) | PROTEIN-CHAPERONE COMPLEX, IMMUNOGLOBIN-LIKE FOLD, INVOLVED IN TYPE 1 PILUS ASSEMBLY, STRUCTURAL PROTEIN-CHAPERONE COMPLEX
4dwh:C (LYS130) to (GLU154) STRUCTURE OF THE MAJOR TYPE 1 PILUS SUBUNIT FIMA BOUND TO THE FIMC (2.5 A RESOLUTION) | PROTEIN-CHAPERONE COMPLEX, IMMUNOGLOBIN-LIKE FOLD, INVOLVED IN TYPE 1 PILUS ASSEMBLY, STRUCTURAL PROTEIN-CHAPERONE COMPLEX
4uic:A (ASN652) to (ASN695) CRYSTAL STRUCTURE OF THE S-LAYER PROTEIN RSBSC(31-844) | SUGAR BINDING PROTEIN, S-LAYER, SBSC, G. STEAROTHERMOPHILUS
4umw:A (ALA280) to (GLU316) CRYSTAL STRUCTURE OF A ZINC-TRANSPORTING PIB-TYPE ATPASE IN E2.PI STATE | CPC, CXXC, ATP-BINDING, HYDROLASE, ION TRANSPORT, MAGNESIUM, ZN2+, METAL-BINDING, NUCLEOTIDE-BINDING, TRANSMEMBRANE, TRANSPORT, HEAVY-METAL BINDING, P-TYPE ATPASE, PIB-ATPASE, ZN2+ EXPORTING, ZINC TRANSPORT, PI-ATPASE, MEMBRANE PROTEIN
5i5w:A (LEU226) to (TRP247) X-RAY CRYSTAL STRUCTURE AT 2.40A RESOLUTION OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A BIARYL AMIDE COMPOUND AND AN INTERNAL ALDIMINE LINKED PLP COFACTOR. | FOLD TYPE IV, TRANSFERASE
5i5x:A (LEU226) to (TRP247) X-RAY CRYSTAL STRUCTURE AT 1.65A RESOLUTION OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A THIAZOLE COMPOUND AND PMP COFACTOR. | FOLD TYPE IV, TRANSFERASE
4dx8:E (GLU108) to (HIS131) ICAP1 IN COMPLEX WITH KRIT1 N-TERMINUS | PROTEIN-PROTIEN COMPLEX, PTB DOMAIN, NUDIX FOLD, PROTEIN-PROTEIN INTERACTION, MEMBRANE, NUCLEUS, PROTEIN BINDING
4dy7:E (GLN30) to (LEU53) CRYSTAL STRUCTURES OF PROTEASE NEXIN-1 IN COMPLEX WITH S195A THROMBIN | SERPIN, PROTEASE, HEPARIN, CELL SURFACE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4dyj:A (ALA280) to (ARG309) CRYSTAL STRUCTURE OF A BROAD SPECIFICITY AMINO ACID RACEMASE (BAR) WITHIN INTERNAL ALDIMINE LINKAGE | ISOMERASE, PLP BINDING, RACEMIZATION
4dyj:B (ALA280) to (ARG309) CRYSTAL STRUCTURE OF A BROAD SPECIFICITY AMINO ACID RACEMASE (BAR) WITHIN INTERNAL ALDIMINE LINKAGE | ISOMERASE, PLP BINDING, RACEMIZATION
3plk:A (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEILE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, PROTEIN BINDING, DUODENUM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3plp:A (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEILE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, PROTEIN BINDING, DUODENUM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4dza:A (VAL278) to (ARG307) CRYSTAL STRUCTURE OF A LYSINE RACEMASE WITHIN INTERNAL ALDIMINE LINKAGE | ISOMERASE, PLP BINDING, RACEMIZATION
3pmg:A (SER371) to (LEU391) STRUCTURE OF RABBIT MUSCLE PHOSPHOGLUCOMUTASE AT 2.4 ANGSTROMS RESOLUTION. USE OF FREEZING POINT DEPRESSANT AND REDUCED TEMPERATURE TO ENHANCE DIFFRACTIVITY | PHOSPHOGLUCOMUTASE, PHOSPHOTRANSFERASE
3pmg:B (SER371) to (LEU391) STRUCTURE OF RABBIT MUSCLE PHOSPHOGLUCOMUTASE AT 2.4 ANGSTROMS RESOLUTION. USE OF FREEZING POINT DEPRESSANT AND REDUCED TEMPERATURE TO ENHANCE DIFFRACTIVITY | PHOSPHOGLUCOMUTASE, PHOSPHOTRANSFERASE
3pmi:C (LYS431) to (SER459) PWWP DOMAIN OF HUMAN MUTATED MELANOMA-ASSOCIATED ANTIGEN 1 | STRUCTURAL GENOMICS CONSORTIUM, SGC, PROTEIN BINDING, NUCLEUS
3po1:B (GLN51) to (THR76) THROMBIN IN COMPLEX WITH BENZOTHIAZOLE GUANIDINE | SERINE PROTEASE, COAGULATION FACTOR II, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5i6i:B (ASP1471) to (VAL1507) CRYSTAL STRUCTURE OF A DBCCP-VARIANT OF CHAETOMIUM THERMOPHILUM ACETYL-COA CARBOXYLASE | CARBOXYLASE, FATTY ACID METABOLISM, MULTIENZYME, CARRIER PROTEIN- DEPENDENT ENZYME, LIGASE
4upd:A (THR13) to (GLY37) OPEN CONFORMATION OF O. PICEAE STEROL ESTERASE MUTANT I544W | HYDROLASE
4upd:B (THR13) to (GLY37) OPEN CONFORMATION OF O. PICEAE STEROL ESTERASE MUTANT I544W | HYDROLASE
4e3b:B (PHE32) to (GLN80) CRYSTAL STRUCTURE OF TAX-INTERACTING PROTEIN-1 (TIP-1) PDZ DOMAIN BOUND TO ICAL36-L (ANSRWPTSIL) PEPTIDE | PDZ-PEPTIDE COMPLEX, SIGNALING PROTEIN-PROTEIN BINDING COMPLEX
5ied:A (ASP766) to (TYR790) MURINE ENDOPLASMIC RETICULUM ALPHA-GLUCOSIDASE II WITH CASTANOSPERMINE | ENZYME GLYCOSYL HYDROLASE GH31 QUALITY CONTROL EXOGLYCOSIDASE, HYDROLASE
4e7l:A (GLN27) to (PRO50) PFV INTEGRASE STRAND TRANSFER COMPLEX (STC-MN*) FOLLOWING REACTION IN CRYSTALLO, AT 3.0 A RESOLUTION. | PROTEIN-DNA COMPLEX, TETRAMER, HHCC MOTIF, ENDONUCLEASE, METAL- BINDING, MULTIFUNCTIONAL ENZYME, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, TRANSFERASE, VIRION, DNA-BINDING, ZINC-BINDING, VIRAL PROTEIN, RECOMBINATION, VIRAL PROTEIN-DNA COMPLEX, RECOMBINATION-DNA COMPLEX
4ebw:A (ARG421) to (ASN458) STRUCTURE OF FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH NOVEL ALLOSTERIC INHIBITOR | KINASE DOMAIN, ALLOSTERIC INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ecl:B (LEU253) to (ARG273) CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF VANCOMYCIN RESISTANCE SERINE RACEMASE VANTG | ANTIBIOTIC RESISTANCE, VANCOMYCIN RESISTANCE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES (CSGID), ALPHA/BETA BARREL, TIM BARREL, TYPE III PYRIDOXAL 5-PHOSPHATE (PLP)-DEPENDENT ENZYME, ACYLTRANSFERASE FAMILY, L-SERINE RACEMASE, D-SERINE RACEMASE, ISOMERASE, L-SERINE, D-SERINE, PLP, PYRIDOXAL 5-PHOSPHATE, CYTOPLASMIC
3puf:H (MET36) to (LYS67) CRYSTAL STRUCTURE OF HUMAN RNASE H2 COMPLEX | RNASE H FOLD, TRIPLE BARREL FOLD, HYDROLASE, RNASE H
3pun:B (GLU468) to (ALA497) CRYSTAL STRUCTURE OF P DOMAIN DIMER OF NOROVIRUS VA207 WITH LEWIS Y TETRASACCHARIDE | GREEK KEY, MIXED ALPHA/BETA STRUCTURE, RECEPTOR BINDING, CARBOHYDRATE/SUGAR BINDING, CAPSID, VIRAL PROTEIN
3puy:F (ILE186) to (GLY206) CRYSTAL STRUCTURE OF AN OUTWARD-FACING MBP-MALTOSE TRANSPORTER COMPLEX BOUND TO AMP-PNP AFTER CRYSTAL SOAKING OF THE PRETRANSLOCATION STATE | ATP BINDING CASSETTE, NUCLEOTIDE BINDING DOMAIN, SUBSTRATE BINDING PROTEIN, ABC TRANSPORTER, IMPORTER, ATPASE, ATP BINDING, MALTODEXTRIN BINDING, TRANSMEMBRANE INTEGRAL MEMBRANE, TRANSPORT PROTEIN, MEMBRANE PROTEIN
5ikj:A (ASN139) to (SER171) STRUCTURE OF CLR2 BOUND TO THE CLR1 C-TERMINUS | METHYL-CPG-BINDING DOMAIN, BAH DOMAIN, CHROMOBARREL DOMAIN, COMPLEX, CELL CYCLE, TRANSCRIPTION
3pvq:A (LYS105) to (ALA131) CRYSTAL STRUCTURE OF A PUTATIVE DIPEPTIDYL-PEPTIDASE VI (BT_1314) FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 AT 2.10 A RESOLUTION | CYSTEINE PROTEINASE FOLD, SH3-LIKE BARREL, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, HYDROLASE
3pvq:B (LYS105) to (ALA131) CRYSTAL STRUCTURE OF A PUTATIVE DIPEPTIDYL-PEPTIDASE VI (BT_1314) FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 AT 2.10 A RESOLUTION | CYSTEINE PROTEINASE FOLD, SH3-LIKE BARREL, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, HYDROLASE
3pwb:A (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217ILE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, PROTEIN BINDING, DUODENUM
3pxk:A (ARG421) to (CYS456) FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH PYRROLO[2,3- D]THIAZOLE | TYROSINE PROTEIN KINASE, TRANSFERASE, ATP BINDING
3pxk:B (ARG421) to (CYS456) FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH PYRROLO[2,3- D]THIAZOLE | TYROSINE PROTEIN KINASE, TRANSFERASE, ATP BINDING
3pyh:A (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217ILE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, PROTEIN BINDING, DUODENUM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4elz:C (THR5) to (PRO42) CCDBVFI:GYRA14VFI | ALPHA+BETA, TOPOISOMERASE, TOXIN-ISOMERASE COMPLEX
4elz:D (LEU6) to (PRO42) CCDBVFI:GYRA14VFI | ALPHA+BETA, TOPOISOMERASE, TOXIN-ISOMERASE COMPLEX
5ip9:I (TYR15) to (GLU37) STRUCTURE OF RNA POLYMERASE II-TFIIF COMPLEX | TRANSCRIPTION
5ip9:K (LYS18) to (HIS40) STRUCTURE OF RNA POLYMERASE II-TFIIF COMPLEX | TRANSCRIPTION
4emz:B (VAL133) to (SER187) HIV-1 NEF IN COMPLEX WITH MHC-I CYTOPLASMIC DOMAIN AND MU1 ADAPTIN SUBUNIT OF AP1 ADAPTOR (SECOND DOMAIN) | HUMAN IMMUNODEFICIENCY VIRUS 1, HIV, NEF, MHC-I, ANTIGEN PRESENTATION, HOST DEFENSE, ADAPTOR PROTEIN COMPLEX 1, MU1 ADAPTIN SUBUNIT, SORTING MOTIF RECOGNITION, CLASP, MEMBRANE TRAFFICKING, VIRAL HIJACKING, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
3q0y:A (PRO122) to (ILE151) N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P | CENTROSOME PROTEIN, STRUCTURAL PROTEIN
3q0y:B (PRO122) to (ILE151) N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P | CENTROSOME PROTEIN, STRUCTURAL PROTEIN
3q0y:C (PRO122) to (ILE151) N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P | CENTROSOME PROTEIN, STRUCTURAL PROTEIN
3q0y:D (PRO122) to (ILE151) N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P | CENTROSOME PROTEIN, STRUCTURAL PROTEIN
3q0y:F (PRO122) to (ILE151) N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P | CENTROSOME PROTEIN, STRUCTURAL PROTEIN
4enf:A (TRP449) to (LYS482) CRYSTAL STRUCTURE OF THE CAP-BINDING DOMAIN OF POLYMERASE BASIC PROTEIN 2 FROM INFLUENZA VIRUS A/PUERTO RICO/8/34(H1N1) | CAP-BINDING PROTEIN, TRANSCRIPTION
4enz:A (ARG261) to (LYS288) STRUCTURE OF HUMAN CERULOPLASMIN AT 2.6 A RESOLUTION | PLASTOCYANIN-LIKE DOMAINS, OXIDOREDUCTASE
3q39:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH HBGA TYPE H2 (DIGLYCAN) | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
3q39:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH HBGA TYPE H2 (DIGLYCAN) | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
3q3a:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH HBGA TYPE H2 (TRIGLYCAN) | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
3q3a:B (GLY332) to (TRP381) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH HBGA TYPE H2 (TRIGLYCAN) | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
4eon:C (ASN3) to (ASP38) THR 160 PHOSPHORYLATED CDK2 H84S, Q85M, Q131E - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR RO3306 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eos:A (ASN3) to (ASP38) THR 160 PHOSPHORYLATED CDK2 WT - HUMAN CYCLIN A3 COMPLEX WITH THE INHIBITOR RO3306 | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ep2:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE SINGLE CHAIN WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH THE SUBSTRATE RT-RH | HIV-1 PROTEASE, SPECIFICITY DESIGN, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE SUBSTRATE COMPLEX
4epl:A (TYR360) to (GLY404) CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA GH3.11 (JAR1) IN COMPLEX WITH JA-ILE | ANL ADENYLATING ENZYME, ACYL ACID-AMIDO SYNTHETASE, ADENYLATION, LIGASE
4uwa:A (GLU19) to (PRO51) STRUCTURE OF THE RYANODINE RECEPTOR AT RESOLUTION OF 6.1 A IN CLOSED STATE | SIGNALING PROTEIN, SIGANLING PRTEIN, CALCIUM BINDING, ION CHANNEL, MUSCULAR CONTRACTION, CONFORMATIONAL CHANGES.
4uwa:B (GLU19) to (PRO51) STRUCTURE OF THE RYANODINE RECEPTOR AT RESOLUTION OF 6.1 A IN CLOSED STATE | SIGNALING PROTEIN, SIGANLING PRTEIN, CALCIUM BINDING, ION CHANNEL, MUSCULAR CONTRACTION, CONFORMATIONAL CHANGES.
4uwa:C (GLU19) to (PRO51) STRUCTURE OF THE RYANODINE RECEPTOR AT RESOLUTION OF 6.1 A IN CLOSED STATE | SIGNALING PROTEIN, SIGANLING PRTEIN, CALCIUM BINDING, ION CHANNEL, MUSCULAR CONTRACTION, CONFORMATIONAL CHANGES.
4uwa:D (GLU19) to (PRO51) STRUCTURE OF THE RYANODINE RECEPTOR AT RESOLUTION OF 6.1 A IN CLOSED STATE | SIGNALING PROTEIN, SIGANLING PRTEIN, CALCIUM BINDING, ION CHANNEL, MUSCULAR CONTRACTION, CONFORMATIONAL CHANGES.
3q6q:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH DISORDERED HBGA TYPE LEA | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
3q6q:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH DISORDERED HBGA TYPE LEA | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
3q6r:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH DISORDERED HBGA TYPE LEX | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
3q6r:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH DISORDERED HBGA TYPE LEX | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
5iuh:A (ILE1116) to (PRO1153) CRYSTAL STRUCTURE OF THE ANAPLASTIC LYMPHOMA KINASE (ALK) IN COMPLEX WITH 5D | CATALYTIC DOMAIN, TRANSFERASE
3q8a:A (LEU20) to (SER47) CRYSTAL STRUCTURE OF WT PROTECTIVE ANTIGEN (PH 5.5) | PROTECTIVE ANTIGEN, ANTHRAX, PH STABILITY, PROTEIN BINDING, TOXIN
3q8a:A (ASN268) to (LEU338) CRYSTAL STRUCTURE OF WT PROTECTIVE ANTIGEN (PH 5.5) | PROTECTIVE ANTIGEN, ANTHRAX, PH STABILITY, PROTEIN BINDING, TOXIN
5iw4:A (HIS103) to (ASP138) CRYSTAL STRUCTURE OF E. COLI NUDC IN COMPLEX WITH NAD | NAD, RNA, CAPPING, NUDIX, HYDROLASE
3q8f:A (LEU20) to (SER47) CRYSTAL STRUCTURE OF 2-FLUOROHISTINE LABELED PROTECTIVE ANTIGEN (PH 5.8) | PROTECTIVE ANTIGEN; 2-FLUOROHISTIDINE; ANTHRAX; PH STABILITY, PROTEIN BINDING
5iy6:U (ASN270) to (TRP298) HUMAN HOLO-PIC IN THE CLOSED STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
5iy7:I (TYR25) to (GLU47) HUMAN HOLO-PIC IN THE OPEN STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
5iy7:K (LYS18) to (HIS40) HUMAN HOLO-PIC IN THE OPEN STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
3qbg:A (GLY104) to (GLY122) ANION-FREE BLUE FORM OF PHARAONIS HALORHODOPSIN | MEMBRANE PROTEIN, ION PUMP, RETINAL, MEMBRANE
3qbg:B (GLY104) to (GLY122) ANION-FREE BLUE FORM OF PHARAONIS HALORHODOPSIN | MEMBRANE PROTEIN, ION PUMP, RETINAL, MEMBRANE
3qbl:A (GLY104) to (GLY122) PHARAONIS HALORHODOPSIN COMPLEXED WITH NITRATE | MEMBRANE PROTEIN, RETINAL PROTEIN, ION PUMP
5iyb:I (TYR25) to (GLU47) HUMAN CORE-PIC IN THE OPEN STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
5iyb:K (LYS18) to (HIS40) HUMAN CORE-PIC IN THE OPEN STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
4f4o:C (ALA118) to (LEU139) STRUCTURE OF THE HAPTOGLOBIN-HAEMOGLOBIN COMPLEX | GLOBIN FOLD, SERINE PROTEASE FOLD, COMPLEMENT CONTROL PROTEIN, HAEMOGLOBIN SCAVENGING, OXYGEN STORAGE-TRANSPORT COMPLEX, OXYGEN TRANSPORT-TRANSPORT PROTEIN COMPLEX
4f4o:I (ALA118) to (THR141) STRUCTURE OF THE HAPTOGLOBIN-HAEMOGLOBIN COMPLEX | GLOBIN FOLD, SERINE PROTEASE FOLD, COMPLEMENT CONTROL PROTEIN, HAEMOGLOBIN SCAVENGING, OXYGEN STORAGE-TRANSPORT COMPLEX, OXYGEN TRANSPORT-TRANSPORT PROTEIN COMPLEX
4f4o:L (ALA118) to (THR141) STRUCTURE OF THE HAPTOGLOBIN-HAEMOGLOBIN COMPLEX | GLOBIN FOLD, SERINE PROTEASE FOLD, COMPLEMENT CONTROL PROTEIN, HAEMOGLOBIN SCAVENGING, OXYGEN STORAGE-TRANSPORT COMPLEX, OXYGEN TRANSPORT-TRANSPORT PROTEIN COMPLEX
5j3t:B (ILE96) to (PHE125) CRYSTAL STRUCTURE OF S. POMBE DCP2:DCP1:EDC1 MRNA DECAPPING COMPLEX | HYDROLASE, DECAPPING, MRNA DECAY, EVH1, NUDIX
5j3y:B (ILE96) to (PHE125) CRYSTAL STRUCTURE OF S. POMBE DCP2:DCP1 MRNA DECAPPING COMPLEX | HYDROLASE, DECAPPING, MRNA DECAY, EVH1, NUDIX
5j3y:D (ILE96) to (PHE125) CRYSTAL STRUCTURE OF S. POMBE DCP2:DCP1 MRNA DECAPPING COMPLEX | HYDROLASE, DECAPPING, MRNA DECAY, EVH1, NUDIX
4uwe:A (GLU19) to (PRO51) STRUCTURE OF THE RYANODINE RECEPTOR AT RESOLUTION OF 8.5 A IN PARTIALLY OPEN STATE | SIGNALING PROTEIN, CALCIUM BINDING, ION CHANNEL, MUSCULAR CONTRACTION, CONFORMATIONAL CHANGES.
4uwe:B (GLU19) to (PRO51) STRUCTURE OF THE RYANODINE RECEPTOR AT RESOLUTION OF 8.5 A IN PARTIALLY OPEN STATE | SIGNALING PROTEIN, CALCIUM BINDING, ION CHANNEL, MUSCULAR CONTRACTION, CONFORMATIONAL CHANGES.
4uwe:C (GLU19) to (PRO51) STRUCTURE OF THE RYANODINE RECEPTOR AT RESOLUTION OF 8.5 A IN PARTIALLY OPEN STATE | SIGNALING PROTEIN, CALCIUM BINDING, ION CHANNEL, MUSCULAR CONTRACTION, CONFORMATIONAL CHANGES.
4uwe:D (GLU19) to (PRO51) STRUCTURE OF THE RYANODINE RECEPTOR AT RESOLUTION OF 8.5 A IN PARTIALLY OPEN STATE | SIGNALING PROTEIN, CALCIUM BINDING, ION CHANNEL, MUSCULAR CONTRACTION, CONFORMATIONAL CHANGES.
4uy4:A (ARG44) to (ASP79) 1.86 A STRUCTURE OF HUMAN SPINDLIN-4 PROTEIN IN COMPLEX WITH HISTONE H3K4ME3 PEPTIDE | PEPTIDE BINDING PROTEIN, SPINDLIN MEMBER 4, SPIN4, TUDOR DOMAIN, EPIGENETIC, CYSTICERCOSIS, MENINGOENCEPHALITIS
4uy4:A (VAL123) to (TYR152) 1.86 A STRUCTURE OF HUMAN SPINDLIN-4 PROTEIN IN COMPLEX WITH HISTONE H3K4ME3 PEPTIDE | PEPTIDE BINDING PROTEIN, SPINDLIN MEMBER 4, SPIN4, TUDOR DOMAIN, EPIGENETIC, CYSTICERCOSIS, MENINGOENCEPHALITIS
4uy4:A (LYS193) to (ASP225) 1.86 A STRUCTURE OF HUMAN SPINDLIN-4 PROTEIN IN COMPLEX WITH HISTONE H3K4ME3 PEPTIDE | PEPTIDE BINDING PROTEIN, SPINDLIN MEMBER 4, SPIN4, TUDOR DOMAIN, EPIGENETIC, CYSTICERCOSIS, MENINGOENCEPHALITIS
4uy4:B (CYS43) to (ASP79) 1.86 A STRUCTURE OF HUMAN SPINDLIN-4 PROTEIN IN COMPLEX WITH HISTONE H3K4ME3 PEPTIDE | PEPTIDE BINDING PROTEIN, SPINDLIN MEMBER 4, SPIN4, TUDOR DOMAIN, EPIGENETIC, CYSTICERCOSIS, MENINGOENCEPHALITIS
4uy4:B (VAL123) to (TYR156) 1.86 A STRUCTURE OF HUMAN SPINDLIN-4 PROTEIN IN COMPLEX WITH HISTONE H3K4ME3 PEPTIDE | PEPTIDE BINDING PROTEIN, SPINDLIN MEMBER 4, SPIN4, TUDOR DOMAIN, EPIGENETIC, CYSTICERCOSIS, MENINGOENCEPHALITIS
4uy4:B (LYS198) to (ASP230) 1.86 A STRUCTURE OF HUMAN SPINDLIN-4 PROTEIN IN COMPLEX WITH HISTONE H3K4ME3 PEPTIDE | PEPTIDE BINDING PROTEIN, SPINDLIN MEMBER 4, SPIN4, TUDOR DOMAIN, EPIGENETIC, CYSTICERCOSIS, MENINGOENCEPHALITIS
3qn7:A (PHE15) to (SER43) POTENT AND SELECTIVE BICYCLIC PEPTIDE INHIBITOR (UK18) OF HUMAN UROKINASE-TYPE PLASMINOGEN ACTIVATOR(UPA) | BICYCLIC PEPTIDE INHIBITOR, CHYMOTRYPSIN FOLD, SERINE PROTEASE, UROKINASE RECEPTOR (UPAR), EXTRACELLULAR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4uzm:A (ALA94) to (PRO120) SHOTGUN PROTEOLYSIS: A PRACTICAL APPLICATION | STRUCTURAL PROTEIN
4fbv:A (GLY191) to (GLY227) CRYSTAL STRUCTURE OF THE MYXOCOCCUS XANTHUS HEMAGGLUTININ IN COMPLEX WITH A3,A6-MANNOPENTAOSE | BETA-BARREL, HIV-INACTIVATING, CARBOHYDRATE BINDING PROTEIN
3qrj:A (ASP241) to (THR272) THE CRYSTAL STRUCTURE OF HUMAN ABL1 KINASE DOMAIN T315I MUTANT IN COMPLEX WITH DCC-2036 | ABL1, KINASE, KINASE DOMAIN, T315I, GATEKEEPER MUTATION, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3qrj:B (THR243) to (GLU275) THE CRYSTAL STRUCTURE OF HUMAN ABL1 KINASE DOMAIN T315I MUTANT IN COMPLEX WITH DCC-2036 | ABL1, KINASE, KINASE DOMAIN, T315I, GATEKEEPER MUTATION, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4fe9:A (LYS79) to (ALA106) CRYSTAL STRUCTURE OF SUSF FROM BACTEROIDES THETAIOTAOMICRON | STARCH BINDING, IG FOLD, EXTRACELLULAR SURFACE, OUTERMEMBRANE, CARBOHYDRATE-BINDING PROTEIN
4fes:A (LEU264) to (TYR290) STRUCTURE OF OSH4 IN COMPLEX WITH CHOLESTEROL ANALOGS | OXYSTEROL, STEROL BINDING PROTEIN, LIPID BINDING PROTEIN
3qtv:H (GLN30) to (THR54) THROMBIN INHIBITION BY PYRIDIN DERIVATIVES | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, BLOOD CLOTTING INHIBITOR, THROMBIN INHIBITOR, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4v25:A (GLN333) to (PRO364) VER-246608, A NOVEL PAN-ISOFORM ATP COMPETITIVE INHIBITOR OF PYRUVATE DEHYDROGENASE KINASE, DISRUPTS WARBURG METABOLISM AND INDUCES CONTEXT-DEPENDENT CYTOSTASIS IN CANCER CELLS | TRANSFERASE, GLYCOLYSIS, WARBURG METABOLISM, NOV3R
3qum:P (GLY197) to (TYR228) CRYSTAL STRUCTURE OF HUMAN PROSTATE SPECIFIC ANTIGEN (PSA) IN FAB SANDWICH WITH A HIGH AFFINITY AND A PCA SELECTIVE ANTIBODY | KALLIKREIN FOLD, PROSTATE-SPECIFIC ANTIGEN, SERINE PROTEASE, NEGATIVE REGULATION OF ANGIOGENESIS, NATURAL POST-TRANSDUCTIONAL MODIFICATION, N-LINKED AND O-LINKED GLYCOSYLATION, IMMUNE SYSTEM
3qv9:A (GLY140) to (ASN168) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI PYRUVATE KINASE(TCPYK)IN COMPLEX WITH PONCEAU S. | PYRUVATE KINASE, GLYCOLYSIS, TIM BARREL, SUGAR KINASE, ADP/ATP BINDING, CYTOSOL, TRANSFERASE
4v3l:C (LEU396) to (HIS436) RNF38-UB-UBCH5B-UB COMPLEX | LIGASE, UBIQUITIN, RING E3, E2
3qwc:H (GLN30) to (THR54) THROMBIN INHIBITION BY PYRIDIN DERIVATIVES | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, BLOOD CLOTTING INHIBITOR, THROMBIN INHIBITOR, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4w7p:A (GLY193) to (ASP232) CRYSTAL STRUCTURE OF ROCK 1 BOUND TO YB-15-QD37 | INHIBITOR, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3r3g:B (GLN30) to (THR54) STRUCTURE OF HUMAN THROMBIN WITH RESIDUES 145-150 OF MURINE THROMBIN. | SERINE PROTEASE, HYDROLASE
3ra8:A (TYR486) to (PRO522) STRUCTURAL STUDIES OF AAV8 CAPSID TRANSITIONS ASSOCIATED WITH ENDOSOMAL TRAFFICKING | BETA BARREL, VIRAL CAPSID, VIRUS
5jdu:B (GLN30) to (THR54) CRYSTAL STRUCTURE FOR HUMAN THROMBIN MUTANT D189A | SERINE PROTEASE, COAGULATION, CONFORMATIONAL EQUILIBRIUM, HYDROLASE
5jdu:D (GLN30) to (THR54) CRYSTAL STRUCTURE FOR HUMAN THROMBIN MUTANT D189A | SERINE PROTEASE, COAGULATION, CONFORMATIONAL EQUILIBRIUM, HYDROLASE
5jdz:B (GLY160) to (SER193) CRYSTAL STRUCTURE OF BURKHOLDERIA GLUMAE TOXA WITH BOUND S- ADENOSYLHOMOCYSTEINE (SAH) | N-METHYLTRANSFERASE, S-ADENOSYLMETHIONINE (SAM), PRODUCT, COMPLEX, TRANSFERASE
5je3:B (GLY160) to (SER193) CRYSTAL STRUCTURE OF BURKHOLDERIA GLUMAE TOXA Y7A MUTANT WITH BOUND S- ADENOSYLHOMOCYSTEINE (SAH) | N-METHYLTRANSFERASE, S-ADENOSYLMETHIONINE (SAM), MUTANT, PRODUCT COMPLEX, TRANSFERASE
3rbb:C (ILE137) to (SER191) HIV-1 NEF PROTEIN IN COMPLEX WITH ENGINEERED HCK SH3 DOMAIN | HIV-1 NEF, DILEUCINE MOTIF, SH3 DOMAIN, RECEPTOR INTERNALIZATION, PXXP MOTIF, PROTEIN BINDING, VIRAL PROTEIN
4fny:A (ASN1115) to (PRO1153) CRYSTAL STRUCTURE OF THE R1275Q ANAPLASTIC LYMPHOMA KINASE CATALYTIC DOMAIN IN COMPLEX WITH A BENZOXAZOLE INHIBITOR | RECEPTOR TYROSINE KINASE, INHIBITOR, CRIZOTINIB, NEUROBLASTOMA, CD246, PHOSPHOTRANSFERASE, NPM-ALK, EML4-ALK, TRANSFERASE-INHIBITOR COMPLEX
4foq:A (GLY361) to (ARG386) CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH 2-AMINOETHANESULFONIC ACID | HYDROLASE, GLYCOSIDASE, DRUG DESIGN, NEURAMINIDASE, INTRAMOLECULAR TRANS-SIALIDASE, HYDROLASE-INHIBITOR COMPLEX
3rfb:A (PHE50) to (LEU74) STRUCTURE OF FRMSR | FRMSR, GAF, OXIDOREDUCTASE, SME
3rgl:B (GLU112) to (TYR141) THE CRYSTAL STRUCTURE OF GLYCYL-TRNA SYNTHETASE SUBUNIT ALPHA FROM CAMPYLOBACTER JEJUNI SUBSP. JEJUNI NCTC IN COMPLEX WITH ATP AND GLYCINE | ALPHA/BETA PROTEIN, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, LIGASE
4fr4:B (HIS22) to (ASN55) CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE-PROTEIN KINASE 32A (YANK1) | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
4fr4:C (HIS22) to (ASN55) CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE-PROTEIN KINASE 32A (YANK1) | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
4fr4:D (HIS22) to (ASN55) CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE-PROTEIN KINASE 32A (YANK1) | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
4fr4:E (HIS22) to (ASN55) CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE-PROTEIN KINASE 32A (YANK1) | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
4fr4:F (HIS22) to (ASN55) CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE-PROTEIN KINASE 32A (YANK1) | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
4fsl:A (MET66) to (GLY89) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-DB-MUT) COMPLEX WITH N-(N-(4- ACETAMIDO-3-CHLORO-5-METHYLBENZYL) CARBAMIMIDOYL)-3-(4- METHOXYPHENYL)-5-METHYL-4-ISOTHIAZOLECARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2, BASE, ASPARTIC PROTEASE, HYDROLASE-INHIBITOR COMPLEX
4ft2:B (VAL192) to (ARG227) CRYSTAL STRUCTURE OF ZEA MAYS ZMET2 IN COMPLEX H3(1-15)K9ME2 PEPTIDE AND SAH | CHROMODOMAIN, BAH DOMAIN, DNA METHYLTRANSFERASE DOMAIN, DNA METHYLTRANSFERASE, H3K9ME2 BINDING, METHYLATION, TRANSFERASE
4ft4:B (VAL192) to (ARG227) CRYSTAL STRUCTURE OF ZEA MAYS ZMET2 IN COMPLEX H3(1-32)K9ME2 PEPTIDE AND SAH | CHROMODOMAIN, BAH DOMAIN, DNA METHYLTRANSFERASE DOMAIN, H3K9ME2 BINDING, METHYLATION, TRANSFERASE
4ft4:A (VAL192) to (ARG227) CRYSTAL STRUCTURE OF ZEA MAYS ZMET2 IN COMPLEX H3(1-32)K9ME2 PEPTIDE AND SAH | CHROMODOMAIN, BAH DOMAIN, DNA METHYLTRANSFERASE DOMAIN, H3K9ME2 BINDING, METHYLATION, TRANSFERASE
5jou:A (ASP778) to (GLU800) BACTEROIDES OVATUS XYLOGLUCAN PUL GH31 | GLYCOSIDE HYDROLASE, GH31, HYDROLASE
5jov:A (ASP778) to (GLU800) BACTEROIDES OVATUS XYLOGLUCAN PUL GH31 WITH BOUND 5FIDOF | GLYCOSIDE HYDROLASE, GH31, HYDROLASE
5jpm:H (GLN459) to (THR480) STRUCTURE OF THE COMPLEX OF HUMAN COMPLEMENT C4 WITH MASP-2 REBUILT USING IMDFF | COMPLEMENT, IMMUNE SYSTEM, BLOOD
5jpq:r (GLY54) to (ARG74) CRYO-EM STRUCTURE OF THE 90S PRE-RIBOSOME | NUCLEAR RNP, RIBOSOME
5jq3:A (GLY212) to (GLN243) CRYSTAL STRUCTURE OF EBOLA GLYCOPROTEIN | EBOLA VIRUS, FILOVIRIDAE, ENVELOPE GLYCOPROTEIN, PROTEIN INHIBITOR COMPLEX, IBUPROFEN, TOREMIFENE, VIRAL PROTEIN
5jq7:A (GLY212) to (GLN243) CRYSTAL STRUCTURE OF EBOLA GLYCOPROTEIN IN COMPLEX WITH TOREMIFENE | EBOLA VIRUS, FILOVIRIDAE, ENVELOPE GLYCOPROTEIN, PROTEIN INHIBITOR COMPLEX, IBUPROFEN, TOREMIFENE, VIRAL PROTEIN
5jqb:A (GLY212) to (GLN243) CRYSTAL STRUCTURE OF EBOLA GLYCOPROTEIN IN COMPLEX WITH IBUPROFEN | EBOLA VIRUS, FILOVIRIDAE, ENVELOPE GLYCOPROTEIN, PROTEIN INHIBITOR COMPLEX, IBUPROFEN, TOREMIFENE, VIRAL PROTEIN
4fxg:G (ASN308) to (GLN336) COMPLEMENT C4 IN COMPLEX WITH MASP-2 | IMMUNE SYSTEM, COMPLEMENT, PROTEOLYTIC CASCADE
4fxg:I (ASN308) to (GLN336) COMPLEMENT C4 IN COMPLEX WITH MASP-2 | IMMUNE SYSTEM, COMPLEMENT, PROTEOLYTIC CASCADE
5jsm:D (GLN456) to (ASN486) BRAFV600E KINASE DOMAIN IN COMPLEX WITH CHEMICALLY LINKED VEMURAFENIB INHIBITOR VEM-3-VEM | KINASE, DIMER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5jtw:F (SER1464) to (ALA1496) CRYSTAL STRUCTURE OF COMPLEMENT C4B RE-REFINED USING IMDFF | INNATE IMMUNE SYSTEM, COMPLEMENT, ACTIVE FORM, IMMUNE SYSTEM
4g6u:B (GLN7) to (ARG33) CDIA-CT/CDII TOXIN AND IMMUNITY COMPLEX FROM ESCHERICHIA COLI | BETA-AUGMENTATION, DNASE, TOXIN, IMMUNITY
4gaw:B (TYR29) to (THR56) CRYSTAL STRUCTURE OF ACTIVE HUMAN GRANZYME H | SERINE PROTEASE, CYTOLYSIS, HYDROLASE, CYTOTOXIC GRANULES
4gaw:D (TYR29) to (THR56) CRYSTAL STRUCTURE OF ACTIVE HUMAN GRANZYME H | SERINE PROTEASE, CYTOLYSIS, HYDROLASE, CYTOTOXIC GRANULES
4gaw:I (MET30) to (THR56) CRYSTAL STRUCTURE OF ACTIVE HUMAN GRANZYME H | SERINE PROTEASE, CYTOLYSIS, HYDROLASE, CYTOTOXIC GRANULES
5ked:B (ARG65) to (GLU101) STRUCTURE OF THE 2.65 ANGSTROM P2(1) CRYSTAL OF K. PNEUMONIA MRKH | MRKH, BIOFILM, K. PNEUMONIA, TRANSFERASE
5ked:C (LYS63) to (GLU101) STRUCTURE OF THE 2.65 ANGSTROM P2(1) CRYSTAL OF K. PNEUMONIA MRKH | MRKH, BIOFILM, K. PNEUMONIA, TRANSFERASE
5ken:E (THR217) to (SER246) EBOV GP IN COMPLEX WITH VARIABLE FAB DOMAINS OF IGGS C4G7 AND C13C6 | EBOLA VIRUS SURFACE GLYCOPROTEIN, THERAPEUTIC ANTIBODY COCKTAIL, ZMAPP, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
5ken:K (THR217) to (GLU245) EBOV GP IN COMPLEX WITH VARIABLE FAB DOMAINS OF IGGS C4G7 AND C13C6 | EBOLA VIRUS SURFACE GLYCOPROTEIN, THERAPEUTIC ANTIBODY COCKTAIL, ZMAPP, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
5kkr:B (GLN665) to (ASP695) KSR2:MEK1 COMPLEX BOUND TO THE SMALL MOLECULE APS-2-79 | KINASE SUPPRESSOR OF RAS SMALL MOLECULE COMPLEX, TRANSFERASE
4gnk:B (ARG359) to (ARG390) CRYSTAL STRUCTURE OF GALPHAQ IN COMPLEX WITH FULL-LENGTH HUMAN PLCBETA3 | GTP-BINDING PROTEIN ALPHA SUBUNITS, PHOSPHOLIPASE C BETA, COILED-COIL DOMAIN, PH DOMAIN, EF HAND, C2 DOMAIN, TIM BARREL DOMAIN, PHOSPHOLIPASE, GTP HYDROLYSIS, G-PROTEIN SIGNALING, MEMBRANE TARGETING, LIPASE, HYDROLASE, CALCIUM BINDING, GTP BINDING, PHOSPHOLIPIDS, GTP-BINDING PROTEIN-HYDROLASE COMPLEX
4gnk:D (ARG359) to (ARG390) CRYSTAL STRUCTURE OF GALPHAQ IN COMPLEX WITH FULL-LENGTH HUMAN PLCBETA3 | GTP-BINDING PROTEIN ALPHA SUBUNITS, PHOSPHOLIPASE C BETA, COILED-COIL DOMAIN, PH DOMAIN, EF HAND, C2 DOMAIN, TIM BARREL DOMAIN, PHOSPHOLIPASE, GTP HYDROLYSIS, G-PROTEIN SIGNALING, MEMBRANE TARGETING, LIPASE, HYDROLASE, CALCIUM BINDING, GTP BINDING, PHOSPHOLIPIDS, GTP-BINDING PROTEIN-HYDROLASE COMPLEX
4gnw:B (GLN65) to (THR108) CRYSTAL STRUCTURE OF NITROPHORIN 4 TRIPLE MUTANT COMPLEX WITH AMMONIA | BETA BARREL, LIPOCALIN, FERRIC HEME, NITRIC OXIDE TRANSPORT, NITRIC OXIDE BINDING, TRANSPORT PROTEIN
5knc:C (GLN117) to (VAL151) CRYSTAL STRUCTURE OF THE 3 ADP-BOUND V1 COMPLEX | P-LOOP, HYDROLASE, NA(+)-ATPASE, ATP BINDING
4goq:B (ALA35) to (VAL67) CRYSTAL STRUCTURE OF A DUF1491 FAMILY PROTEIN (CC_1065) FROM CAULOBACTER CRESCENTUS CB15 AT 1.87 A RESOLUTION | PF07372 FAMILY PROTEIN, DUF1491, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
4goq:C (ALA35) to (VAL67) CRYSTAL STRUCTURE OF A DUF1491 FAMILY PROTEIN (CC_1065) FROM CAULOBACTER CRESCENTUS CB15 AT 1.87 A RESOLUTION | PF07372 FAMILY PROTEIN, DUF1491, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
4goy:B (THR213) to (GLN258) THE CRYSTAL STRUCTURE OF HUMAN FASCIN 1 K41A MUTANT | BETA-TREFOIL, ACTIN BUNDLING PROTEIN, CANCER, METASTASIS, CELL MIGRATION, ACTIN-BINDING, PHOSPHOPROTEIN, PROTEIN BINDING, ACTIN
4gp3:B (THR213) to (GLN258) THE CRYSTAL STRUCTURE OF HUMAN FASCIN 1 K358A MUTANT | BETA-TREFOIL, ACTIN BUNDLING PROTEIN, CANCER, METASTASIS, CELL MIGRATION, ACTIN-BINDING, PHOSPHOPROTEIN, PROTEIN BINDING, ACTIN
5kq5:A (HIS15) to (ASN48) AMPK BOUND TO ALLOSTERIC ACTIVATOR | KINASE ALLOSTERIC ACTIVATOR, TRANSFERASE
5kqy:B (VAL11) to (GLU34) PROTEASE E35D-DRV | HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5kxa:A (HIS420) to (ARG456) SELECTIVE INHIBITION OF AUTOTAXIN IS EFFECTIVE IN MOUSE MODELS OF LIVER FIBROSIS | ENPP2, AUTOTAXIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5kz5:R (LEU251) to (VAL278) ARCHITECTURE OF THE HUMAN MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY MACHINERY: THE COMPLEX FORMED BY THE IRON DONOR, THE SULFUR DONOR, AND THE SCAFFOLD | FRATAXIN, IRON-SULFUR PROTEIN, MITOCHONDRIA, PROTEIN COMPLEX, TRANSFERASE-OXIDOREDUCTASE COMPLEX
5l02:A (TYR348) to (LEU386) S324T VARIANT OF B. PSEUDOMALLEI KATG | CATALASE, PEROXIDASE, KATG, S324T VARIANT, OXIDOREDUCTASE
5l04:A (LEU311) to (SER367) STRUCTURE OF INTERFERON LAMBDA 1 RECEPTOR WITH HUMAN KINASE JAK1 | COMPLEX OF JAK1 AND INTERFERON LAMBDA 1, JAK KINASE, INTRACELLULAR DOMAIN OF IFNLR1, FERM DOMAIN, SH2-LIKE DOMAIN, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
5l7z:A (ARG84) to (LYS106) STRUCTURE OF EXUPERANTIA EXO-LIKE DOMAIN | EXONUCLEASE, RNA, PSEUDO NUCLEASE, HYDROLASE, RNA BINDING PROTEIN
5l8j:A (GLU134) to (PHE165) AURORA-A KINASE DOMAIN IN COMPLEX WITH VNAR-D01 S93R | KINASE, VNAR, INHIBITOR, TRANSFERASE
5l8k:A (GLU134) to (PHE165) AURORA-A KINASE DOMAIN IN COMPLEX WITH VNAR-D01 (CRYSTAL FORM 2) | KINASE, VNAR, INHIBITOR, TRANSFERASE
5lf2:B (LEU582) to (SER617) CRYSTAL STRUCTURE OF LAMININ BETA2 LE5-LF-LE6 | EXTRACELLULAR MATRIX, CELL ADHESION
5lon:A (LYS100) to (PHE130) STRUCTURE OF /K. LACTIS/ DCP1-DCP2 DECAPPING COMPLEX. | RNA DECAY, MULTIPROTEIN COMPLEX, RNA BINDING PROTEIN
5lpe:A (GLN30) to (THR54) KALLIKREIN-RELATED PEPTIDASE 10 COMPLEX WITH ZN2+ | SERINE PROTEASE, ZYMOGEN-LIKE ENZYME, ZN2+ INHIBITION, TUMOR SUPPRESSOR, HYDROLASE
5lxc:B (TYR391) to (GLY416) CRYSTAL STRUCTURE OF DYRK2 IN COMPLEX WITH EHT 5372 (COMPOUND 1) | TRANSFERASE, KINASE, INHIBITOR, UNUSUAL BINDING MODE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
5lzl:D (PHE33) to (VAL59) PYROBACULUM CALIDIFONTIS 5-AMINOLAEVULINIC ACID DEHYDRATASE | TIM-BARREL, TETRAPYRROLE BIOSYNTHESIS, LYASE
5m47:A (SER141) to (PRO167) CRYSTAL STRCUTURE OF DAPF FROM CORYNEBACTERIUM GLUTAMICUM IN COMPLEX WITH D,L-DIAMINOPIMELATE | ISOMERASE
5m51:A (ASP7) to (GLY42) NEK2 BOUND TO ARYLAMINOPURINE COMPOUND 8 | PROTEIN KINASE, INHIBITOR, CENTROSOME SEPARATION, TRANSFERASE- INHIBITOR COMPLEX
5sga:E (GLU29) to (ALA55) STRUCTURES OF PRODUCT AND INHIBITOR COMPLEXES OF STREPTOMYCES GRISEUS PROTEASE A AT 1.8 ANGSTROMS RESOLUTION. A MODEL FOR SERINE PROTEASE CATALYSIS | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5t1v:A (ASP7) to (GLY102) CRYSTAL STRUCTURE OF ZIKA VIRUS NS2B-NS3 PROTEASE IN APO-FORM. | HYDROLASE, PEPTIDASE S7, FLAVIVIRUS NS3 SERINE PROTEASE., STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
5tca:A (MET30) to (SER53) COMPLEMENT FACTOR D INHIBITED WITH JH3 | SERINE PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5tca:B (MET30) to (SER53) COMPLEMENT FACTOR D INHIBITED WITH JH3 | SERINE PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5tca:C (MET30) to (SER53) COMPLEMENT FACTOR D INHIBITED WITH JH3 | SERINE PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5tca:D (MET30) to (SER53) COMPLEMENT FACTOR D INHIBITED WITH JH3 | SERINE PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5tcc:A (MET30) to (SER53) COMPLEMENT FACTOR D INHIBITED WITH JH4 | SERINE PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5tcc:B (MET30) to (SER53) COMPLEMENT FACTOR D INHIBITED WITH JH4 | SERINE PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5tcc:C (MET30) to (SER53) COMPLEMENT FACTOR D INHIBITED WITH JH4 | SERINE PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5tcc:D (MET30) to (SER53) COMPLEMENT FACTOR D INHIBITED WITH JH4 | SERINE PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5tcc:D (GLY200) to (THR229) COMPLEMENT FACTOR D INHIBITED WITH JH4 | SERINE PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5tcc:E (MET30) to (SER53) COMPLEMENT FACTOR D INHIBITED WITH JH4 | SERINE PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5tcc:F (MET30) to (SER53) COMPLEMENT FACTOR D INHIBITED WITH JH4 | SERINE PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5tcc:G (MET30) to (SER53) COMPLEMENT FACTOR D INHIBITED WITH JH4 | SERINE PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
6lpr:A (ILE29) to (ALA55) STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
7i1b:A (GLN38) to (LEU69) HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF INTERLEUKIN- 1 BETA IN SOLUTION BY THREE-AND FOUR-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY | CYTOKINE
8est:E (GLN30) to (THR54) REACTION OF PORCINE PANCREATIC ELASTASE WITH 7-SUBSTITUTED 3-ALKOXY-4-CHLOROISOCOUMARINS: DESIGN OF POTENT INHIBITORS USING THE CRYSTAL STRUCTURE OF THE COMPLEX FORMED WITH 4- CHLORO-3-ETHOXY-7-GUANIDINO-ISOCOUMARIN | HYDROLASE(SERINE PROTEINASE)
8lpr:A (ILE29) to (ALA55) STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
9lpr:A (ILE29) to (ALA55) STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2o8u:A (PHE30) to (SER54) CRYSTAL STRUCTURE AND BINDING EPITOPES OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR (C122A/N145Q/S195A) IN COMPLEX WITH INHIBITORS | UROKINASE-TYPE PLASMINOGEN ACTIVATOR, BENZAMIDINE, PHENYLGUANIDINE, CONTACT AREA, HYDROLASE
2o92:A (THR286) to (GLN310) CRYSTAL STRUCTURE OF A SIGNALLING PROTEIN (SPG-40) COMPLEX WITH TETRASACCHARIDE AT 3.0A RESOLUTION | SACCHARIDE, COMPLEX, SIGNALING PROTEIN
1nbc:A (VAL74) to (LYS115) BACTERIAL TYPE 3A CELLULOSE-BINDING DOMAIN | CELLULOSE DEGRADATION, CELLULOSE-BINDING DOMAIN, CELLULOSOME, SCAFOLDIN
3rmo:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH MI004 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN, HIRUDIN, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2akw:B (PHE624) to (ALA654) CRYSTAL STRUCTURE OF T.THERMOPHILUS PHENYLALANYL-TRNA SYNTHETASE COMPLEXED WITH P-CL-PHENYLALANINE | PROTEIN-UNNATURAL AMINO ACID COMPLEX, LIGASE
1nd6:B (HIS1281) to (LEU1311) CRYSTAL STRUCTURES OF HUMAN PROSTATIC ACID PHOSPHATASE IN COMPLEX WITH A PHOSPHATE ION AND ALPHA-BENZYLAMINOBENZYLPHOSPHONIC ACID UPDATE THE MECHANISTIC PICTURE AND OFFER NEW INSIGHTS INTO INHIBITOR DESIGN | PROSTATIC ACID PHOSPHATASE, PAP, PROSTATE, PHOSPHATE, INHIBITOR, HYDROLASE
3eb7:B (THR614) to (PRO650) CRYSTAL STRUCTURE OF INSECTICIDAL DELTA-ENDOTOXIN CRY8EA1 FROM BACILLUS THURINGIENSIS AT 2.2 ANGSTROMS RESOLUTION | ENDOTOXIN, CRY8E, BACILLUS THURINGIENSIS, TOXIN
2any:A (GLN30) to (THR54) EXPRESSION, CRYSTALLIZATION AND THE THREE-DIMENSIONAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN PLASMA KALLIKREIN: IMPLICATIONS FOR STRUCTURE-BASED DESIGN OF PROTEASE INHIBITORS | MUTAGENICALLY DEGLYCOSYALTED HUMAN PLASMA KALLIKREIN PROTEASE DOMAIN; TRYPSIN-LIKE SERINE PROTEASE, BLOOD CLOTTING, HYDROLASE
3efo:A (LEU73) to (PRO96) CRYSTAL STRUCTURE OF THE MAMMALIAN COPII-COAT PROTEIN SEC23/24 BOUND TO THE TRANSPORT SIGNAL SEQUENCE OF SYNTAXIN 5 | COPII, COAT PROTEIN, TRANSPORT SIGNAL, DISEASE MUTATION, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, GOLGI APPARATUS, MEMBRANE, PROTEIN TRANSPORT, TRANSPORT
2awx:B (PHE331) to (ALA373) SYNAPSE ASSOCIATED PROTEIN 97 PDZ2 DOMAIN VARIANT C378S | MEMBRANE PROTEIN, SYNAPTIC SIGNALING, TRAFFICKING PROTEIN
1nlf:A (PHE232) to (PRO262) CRYSTAL STRUCTURE OF DNA HELICASE REPA IN COMPLEX WITH SULFATE AT 1.95 A RESOLUTION | REPLICATIVE DNA HELICASE STRUCTURAL CHANGES, REPLICATION
4h0l:C (ASP100) to (PRO130) CYTOCHROME B6F COMPLEX CRYSTAL STRUCTURE FROM MASTIGOCLADUS LAMINOSUS WITH N-SIDE INHIBITOR NQNO | ALPHA-HELIX, BETA -SHEET, PLASTOQUINOL-PLASTOCYANIN OXIDOREDUCTASE, PLASTOCYANIN, NONE, THYLAKOID MEMBRANES, PHOTOSYNTHESIS
1anb:A (GLN30) to (SER54) ANIONIC TRYPSIN MUTANT WITH SER 214 REPLACED BY GLU | TRYPSIN, ANIONIC, SERINE PROTEASE, HYDROLASE
1ane:A (GLN30) to (SER54) ANIONIC TRYPSIN WILD TYPE | TRYPSIN, ANIONIC, SERINE PROTEASE, HYDROLASE
2os7:B (ASN157) to (GLY180) CAF1M PERIPLASMIC CHAPERONE TETRAMER | IMMUNOGLOBULIN FOLD, HETERO BETA BARREL, CHAPERONE
4h75:A (ARG57) to (ASP92) CRYSTAL STRUCTURE OF HUMAN SPINDLIN1 IN COMPLEX WITH A HISTONE H3K4(ME3) PEPTIDE | TUDOR DOMAIN, H3K4ME3 BINDING, METHYLATION, GENE REGULATION
4h75:A (VAL137) to (TYR170) CRYSTAL STRUCTURE OF HUMAN SPINDLIN1 IN COMPLEX WITH A HISTONE H3K4(ME3) PEPTIDE | TUDOR DOMAIN, H3K4ME3 BINDING, METHYLATION, GENE REGULATION
4h75:A (LYS216) to (ASP248) CRYSTAL STRUCTURE OF HUMAN SPINDLIN1 IN COMPLEX WITH A HISTONE H3K4(ME3) PEPTIDE | TUDOR DOMAIN, H3K4ME3 BINDING, METHYLATION, GENE REGULATION
1au8:A (TYR29) to (THR54) HUMAN CATHEPSIN G | INFLAMMATION, SPECIFICITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3en0:A (ASP202) to (ALA226) THE STRUCTURE OF CYANOPHYCINASE | SERINE PROTEASE, BETA PEPTIDE SPECIFIC, HYDROLASE, PROTEASE
3en0:B (ASP202) to (ALA226) THE STRUCTURE OF CYANOPHYCINASE | SERINE PROTEASE, BETA PEPTIDE SPECIFIC, HYDROLASE, PROTEASE
3en0:C (ASP202) to (ALA226) THE STRUCTURE OF CYANOPHYCINASE | SERINE PROTEASE, BETA PEPTIDE SPECIFIC, HYDROLASE, PROTEASE
1avu:A (THR16) to (ASN48) TRYPSIN INHIBITOR FROM SOYBEAN (STI) | SERINE PROTEASE INHIBITOR, TRYPSIN INHIBITOR, KUNITZ-TYPE, BETA-TREFOIL FOLD
1az8:A (GLN30) to (SER54) BOVINE TRYPSIN COMPLEXED TO BIS-PHENYLAMIDINE INHIBITOR | HYDROLASE, SERINE PROTEINASE, SERINE PROTEASE
4hat:B (GLY109) to (PRO142) CRYSTAL STRUCTURE OF CRM1 INHIBITOR LEPTOMYCIN B IN COMPLEX WITH CRM1- RAN-RANBP1 | HEAT REPEAT, NUCLEAR EXPORT, RAN-RANBP1, LMB, LEPTOMYCIN B, NUCLEAR, PROTEIN TRANSPORT-ANTIBIOTIC COMPLEX
3eq0:H (GLN30) to (THR54) THROMBIN INHIBITOR | BLOOD CLOTTING, HYDROLASE INHIBITOR, ACUTE PHASE, BLOOD COAGULATION, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, KRINGLE, PROTEASE, SECRETED, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2b9u:C (PRO2) to (GLU29) CRYSTAL STRUCTURE OF DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE FROM SULFOLOBUS TOKODAII | BETA CLASS, JELLY ROLL-LIKE TOPOLOGY, FLATTENED BARREL, ISOMERASE
2b9u:E (PRO2) to (GLU29) CRYSTAL STRUCTURE OF DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE FROM SULFOLOBUS TOKODAII | BETA CLASS, JELLY ROLL-LIKE TOPOLOGY, FLATTENED BARREL, ISOMERASE
1nye:D (ILE623) to (PHE656) CRYSTAL STRUCTURE OF OSMC FROM E. COLI | CRYSTAL STRUCTURE, OSMC, STRUCTURAL GENOMICS, PEROXIREDOXIN, BSGC STRUCTURE FUNDED BY NIH, PROTEIN STRUCTURE INITIATIVE, PSI, BERKELEY STRUCTURAL GENOMICS CENTER, UNKNOWN FUNCTION
4hb0:B (GLY109) to (PRO142) CRYSTAL STRUCTURE OF CRM1 INHIBITOR LEPTOMYCIN B IN COMPLEX WITH CRM1(K541Q,K542Q,R543S,K545Q,K548Q,K579Q)-RAN-RANBP1 | HEAT REPEAT, NUCLEAR EXPORT, RAN-RANBP1, LMB, LEPTOMYCIN B, PROTEIN TRANSPORT-ANTIBIOTIC COMPLEX
4hc5:C (GLY98) to (GLU130) CRYSTAL STRUCTURE OF MEMBER OF GLYOXALASE/BLEOMYCIN RESISTANCE PROTEIN/DIOXYGENASE SUPERFAMILY FROM SPHAEROBACTER THERMOPHILUS DSM 20745 | MCSG, GEBA GENOMES, STRUCTURAL GENOMICS, MIDWEST CENTER FOR STRUCTURAL GENOMICS, PFAM00903, PSI-BIOLOGY, OXIDOREDUCTASE
4hc5:D (GLY98) to (GLU130) CRYSTAL STRUCTURE OF MEMBER OF GLYOXALASE/BLEOMYCIN RESISTANCE PROTEIN/DIOXYGENASE SUPERFAMILY FROM SPHAEROBACTER THERMOPHILUS DSM 20745 | MCSG, GEBA GENOMES, STRUCTURAL GENOMICS, MIDWEST CENTER FOR STRUCTURAL GENOMICS, PFAM00903, PSI-BIOLOGY, OXIDOREDUCTASE
3eqo:B (ASN155) to (ASN182) CRYSTAL STRUCTURE OF BETA-1,3-GLUCANASE FROM PHANEROCHAETE CHRYSOSPORIUM (LAM55A) GLUCONOLACTONE COMPLEX | TANDEM BETA-HELIX DOMAINS, GLYCOSIDASE, HYDROLASE
2bbv:B (THR111) to (PRO146) THE REFINED THREE-DIMENSIONAL STRUCTURE OF AN INSECT VIRUS AT 2.8 ANGSTROMS RESOLUTION | PROTEIN-RNA COMPLEX, DOUBLE HELIX, ICOSAHEDRAL VIRUS, VIRUS/RNA COMPLEX
2bbv:C (THR111) to (PRO146) THE REFINED THREE-DIMENSIONAL STRUCTURE OF AN INSECT VIRUS AT 2.8 ANGSTROMS RESOLUTION | PROTEIN-RNA COMPLEX, DOUBLE HELIX, ICOSAHEDRAL VIRUS, VIRUS/RNA COMPLEX
2p3m:A (ILE80) to (PRO111) SOLUTION STRUCTURE OF MJ0056 | RIFT BARREL, PHOSPHOTRANSFERASE, RIBOFLAVIN KINASE
4hfq:A (LEU69) to (LEU95) CRYSTAL STRUCTURE OF UDP-X DIPHOSPHATASE | UDP-SUGAR DIPHOSPHATASE, NUDIX, HYDROLASE, RNA EXONUCLEASE, PYROPHOSPHATASE, MUR PATHWAY
4hfq:B (LEU69) to (LEU95) CRYSTAL STRUCTURE OF UDP-X DIPHOSPHATASE | UDP-SUGAR DIPHOSPHATASE, NUDIX, HYDROLASE, RNA EXONUCLEASE, PYROPHOSPHATASE, MUR PATHWAY
3s2h:I (MET13) to (GLU37) RNA POLYMERASE II INITIATION COMPLEX WITH A 6-NT RNA CONTAINING A 2[PRIME]-IODO ATP | RNA POLYMERASE II, INITIATION COMPLEX, TRANSCRIPTION-RNA-DNA COMPLEX
1bio:A (MET30) to (SER54) HUMAN COMPLEMENT FACTOR D IN COMPLEX WITH ISATOIC ANHYDRIDE INHIBITOR | SERINE PROTEASE, HYDROLASE, COMPLEMENT, FACTOR D, CATALYTIC TRIAD, SELF-REGULATION
1bju:A (GLN30) to (SER54) BETA-TRYPSIN COMPLEXED WITH ACPU | HYDROLASE, SERINE PROTEASE, DIGESTION, PANCREAS, ZYMOGEN
1o32:A (GLN30) to (SER54) ELABORATE MANIFOLD OF SHORT HYDROGEN BOND ARRAYS MEDIATING BINDING OF ACTIVE SITE-DIRECTED SERINE PROTEASE INHIBITORS | SERINE PROTEASE, SHORT HYDROGEN BOND, INHIBITION MECHANISM, SHIFT OF PKA, TRYPSIN, THROMBIN, UROKINASE, FACTOR XA, HYDROLASE
1o39:A (GLN30) to (SER54) ELABORATE MANIFOLD OF SHORT HYDROGEN BOND ARRAYS MEDIATING BINDING OF ACTIVE SITE-DIRECTED SERINE PROTEASE INHIBITORS | SERINE PROTEASE, SHORT HYDROGEN BOND, INHIBITION MECHANISM, SHIFT OF PKA, TRYPSIN, THROMBIN, UROKINASE, FACTOR XA, HYDROLASE
2bmg:B (GLN30) to (THR54) CRYSTAL STRUCTURE OF FACTOR XA IN COMPLEX WITH 50 | THROMBOSIS, PROTEIN INHIBITOR COMPLEX, BLOOD COAGULATION FACTOR, SERINE PROTEINASE, DRUG DESIGN, HYDROLASE
1boq:A (ILE7) to (ALA34) PRO REGION C-TERMINUS: PROTEASE ACTIVE SITE INTERACTIONS ARE CRITICAL IN CATALYZING THE FOLDING OF ALPHA-LYTIC PROTEASE | SERINE PROTEASE, FOLDING MUTANT, HYDROLASE
3f68:H (GLN30) to (THR54) THROMBIN INHIBITION | BLOOD CLOTTING, HYDROLASE INHIBITOR, ACUTE PHASE, BLOOD COAGULATION, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, KRINGLE, PROTEASE, SECRETED, SERINE PROTEASE, PROTEASE INHIBITOR, SERINE PROTEASE INHIBITOR, SULFATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4x6a:K (LYS18) to (HIS40) CRYSTAL STRUCTURE OF YEAST RNA POLYMERASE II ENCOUNTERING OXIDATIVE CYCLOPURINE DNA LESIONS | POL II ELONGATION COMPLEX OXIDATIVE CYCLOPURINE DNA LESIONS, TRANSCRIPTION-DNA COMPLEX
3f9h:A (VAL18) to (PRO39) CRYSTAL STRUCTURE OF THE F140A MUTANT OF SARS-CORONOVIRUS 3C-LIKE PROTEASE AT PH 7.6 | PROTEASE, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
3f9h:B (VAL18) to (PRO39) CRYSTAL STRUCTURE OF THE F140A MUTANT OF SARS-CORONOVIRUS 3C-LIKE PROTEASE AT PH 7.6 | PROTEASE, CYTOPLASM, HYDROLASE, MEMBRANE, METAL-BINDING, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, THIOL PROTEASE, TRANSMEMBRANE, ZINC, ZINC-FINGER
4x8t:H (GLN30) to (SER54) FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 7-CHLORO-3,4- DIHYDROISOQUINOLIN-1(2H)-ONE | GLYCOPROTEIN, HYDROLASE, SERINE PROTEASE, PLASMA, BLOOD COAGULATION FACTOR, PROTEIN INHIBITOR COMPLEX, CALCIUM- BINDING, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
2bu7:A (GLN333) to (PRO364) CRYSTAL STRUCTURES OF HUMAN PYRUVATE DEHYDROGENASE KINASE 2 CONTAINING PHYSIOLOGICAL AND SYNTHETIC LIGANDS | TRANSFERASE, PYRUVATE DEHYDROGENASE KINASE 2 GHKL MOTIF REGULATION
4xbj:A (GLY216) to (SER240) Y274F ALANINE RACEMASE FROM E. COLI INHIBITED BY L-ALA-P | ISOMERASE, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
4xbj:C (GLY216) to (SER240) Y274F ALANINE RACEMASE FROM E. COLI INHIBITED BY L-ALA-P | ISOMERASE, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
4xet:A (ARG57) to (SER84) FE-CL BOUND Y157F CDO AT PH ~7.0 IN THE PRESENCE OF AZIDE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, CYTOSOL, THIOL DIOXYGENASE, OXIDOREDUCTASE
4xez:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE VARIANT - Y157F AT PH 8.0 WITH DITHIONITE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, CYTOSOL, THIOL DIOXYGENASE, OXIDOREDUCTASE
4xf3:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE VARIANT - Y157F AT PH 8.0 WITH CYSTEINE AND DITHIONITE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, THIOL DIOXYGENASE, OXIDOREDUCTASE
4xfa:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE VARIANT - Y157F AT PH 8.0 IN COMPLEX WITH HOMOCYSTEINE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, THIOL DIOXYGENASE, OXIDOREDUCTASE
4xfg:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE VARIANT - C93A AT PH 6.2 WITH CYSTEINE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, THIOL DIOXYGENASE, OXIDOREDUCTASE
4xfh:A (ARG57) to (SER84) CYSTEINE DIOXYGENASE VARIANT - Y157F AT PH 6.2 WITH CYSTEINE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, THIOL DIOXYGENASE, OXIDOREDUCTASE
1c5m:D (GLN30) to (THR54) STRUCTURAL BASIS FOR SELECTIVITY OF A SMALL MOLECULE, S1- BINDING, SUB-MICROMOLAR INHIBITOR OF UROKINASE TYPE PLASMINOGEN ACTIVATOR | SELECTIVE, S1 SITE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, UROKINASE, TRYPSIN, THROMBIN, BLOOD CLOTTING
1c6x:B (ARG208) to (GLU234) ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP. | HYDROLASE
1ol5:A (GLU134) to (PHE165) STRUCTURE OF AURORA-A 122-403, PHOSPHORYLATED ON THR287, THR288 AND BOUND TO TPX2 1-43 | TRANSFERASE/CELL CYCLE, CELL CYCLE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, PHOSPHORYLATION
3snd:B (VAL18) to (PRO39) CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEASE COMPLEXED WITH AC- ESTLQ-H (COCRYSTALLIZATION) | 3C-LIKE PROTEINASE, PROTEASE, AC-ESTLQ-H, ACTIVE SITE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3sob:B (PRO21) to (VAL46) THE STRUCTURE OF THE FIRST YWTD BETA PROPELLER DOMAIN OF LRP6 IN COMPLEX WITH A FAB | BETA PROPELLER, PROTEIN BINDING-IMMUNE SYSTEM COMPLEX
1p0s:H (GLN30) to (THR54) CRYSTAL STRUCTURE OF BLOOD COAGULATION FACTOR XA IN COMPLEX WITH ECOTIN M84R | FACTOR XA, SERINE PROTEASE, ECOTIN M84R, SERINE PROTEASE INHIBITOR, HYDROLASE
2q99:A (THR293) to (ASP319) CRYSTAL STRUCTURE OF SACCHAROPINE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE | DEHYDROGENASE, ALPHA-AMINOADIPATE PATHWAY, FUNGAL LYSINE SYNTHESIS, ALPHA/BETA PROTEIN, ROSSMANN FOLD, OXIDOREDUCTASE
3sy8:C (GLU157) to (PRO190) CRYSTAL STRUCTURE OF THE RESPONSE REGULATOR ROCR | TIM BARREL PHOSPHODIESTERASE-A, TRANSCRIPTION REGULATOR
3sy8:D (GLU157) to (PRO190) CRYSTAL STRUCTURE OF THE RESPONSE REGULATOR ROCR | TIM BARREL PHOSPHODIESTERASE-A, TRANSCRIPTION REGULATOR
3g8e:A (PRO333) to (GLN352) CRYSTAL STRUCTURE OF RATTUS NORVEGICUS VISFATIN/PBEF/NAMPT IN COMPLEX WITH AN FK866-BASED INHIBITOR | PROTEIN-LIGAND COMPLEX, IS001, CYTOPLASM, GLYCOSYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PYRIDINE NUCLEOTIDE BIOSYNTHESIS, TRANSFERASE
3t29:A (GLN30) to (SER54) TMAO-GROWN TRIGONAL TRYPSIN (BOVINE) | PROTEASE, HYDROLASE
4ip7:D (GLY184) to (GLU210) STRUCTURE OF THE S12D VARIANT OF HUMAN LIVER PYRUVATE KINASE IN COMPLEX WITH CITRATE AND FBP. | KINASE, GLYCOLYSIS, ALLOSTERIC, PHOSPHORYLATION MIMIC, LIVER, TRANSFERASE
1dkg:D (PHE91) to (PRO112) CRYSTAL STRUCTURE OF THE NUCLEOTIDE EXCHANGE FACTOR GRPE BOUND TO THE ATPASE DOMAIN OF THE MOLECULAR CHAPERONE DNAK | HSP70, GRPE, MOLECULAR CHAPERONE, NUCLEOTIDE EXCHANGE FACTOR, COILED-COIL, COMPLEX (HSP24/HSP70)
1dki:A (HIS195) to (ARG223) CRYSTAL STRUCTURE OF THE ZYMOGEN FORM OF STREPTOCOCCAL PYROGENIC EXOTOXIN B ACTIVE SITE (C47S) MUTANT | ZYMOGEN, CYSTEINE PROTEASE, PAPAIN-LIKE, TOXIN
1dki:B (HIS195) to (ARG223) CRYSTAL STRUCTURE OF THE ZYMOGEN FORM OF STREPTOCOCCAL PYROGENIC EXOTOXIN B ACTIVE SITE (C47S) MUTANT | ZYMOGEN, CYSTEINE PROTEASE, PAPAIN-LIKE, TOXIN
2qoh:A (ASP241) to (THR272) CRYSTAL STRUCTURE OF ABL KINASE BOUND WITH PPY-A | ABL, KINASE, INHIBITOR, TRANSFERASE
4isn:A (GLN30) to (SER54) CRYSTAL STRUCTURE OF MATRIPTASE IN COMPLEX WITH ITS INHIBITOR HAI-1 | BETA BARREL, SERINE PROTEASE INHIBITOR, EPITHELIUM, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3gdu:A (VAL154) to (ASP193) CRYSTAL STRUCTURE OF DEGS H198P/D320A MUTANT MODIFIED BY DFP AND IN COMPLEX WITH YRF PEPTIDE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, PERIPLASM, SERINE PROTEASE, HYDROLASE/HYDROLASE ACTIVATOR COMPLEX
3gic:B (GLN30) to (LEU53) STRUCTURE OF THROMBIN MUTANT DELTA(146-149E) IN THE FREE FORM | SERINE PROTEASE, CHYMOTRYPSIN FOLD, ACUTE PHASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, DISULFIDE BOND, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, KRINGLE, PROTEASE, SECRETED, ZYMOGEN
1ppb:H (GLN30) to (THR54) THE REFINED 1.9 ANGSTROMS CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN: INTERACTION WITH D-PHE-PRO-ARG CHLOROMETHYLKETONE AND SIGNIFICANCE OF THE TYR-PRO-PRO-TRP INSERTION SEGMENT | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2qxh:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN KALLIKREIN 7 IN COMPLEX WITH SUC- ALA-ALA-PRO-PHE-CHLOROMETHYLKETONE | 70-80 LOOP, ACTIVE SITE INHIBITOR, CHLOROMETHYL KETONE, ALTERNATIVE SPLICING, GLYCOPROTEIN, HYDROLASE, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN
2qy0:A (PHE301) to (GLU329) ACTIVE DIMERIC STRUCTURE OF THE CATALYTIC DOMAIN OF C1R REVEALS ENZYME-PRODUCT LIKE CONTACTS | COMPLEMENT, SERINE PROTEASE, BETA BARREL, COMPLEMENT PATHWAY, EGF- LIKE DOMAIN, GLYCOPROTEIN, HYDROLASE, HYDROXYLATION, IMMUNE RESPONSE, INNATE IMMUNITY, PHOSPHORYLATION, SUSHI
2qy0:C (PHE301) to (GLU329) ACTIVE DIMERIC STRUCTURE OF THE CATALYTIC DOMAIN OF C1R REVEALS ENZYME-PRODUCT LIKE CONTACTS | COMPLEMENT, SERINE PROTEASE, BETA BARREL, COMPLEMENT PATHWAY, EGF- LIKE DOMAIN, GLYCOPROTEIN, HYDROLASE, HYDROXYLATION, IMMUNE RESPONSE, INNATE IMMUNITY, PHOSPHORYLATION, SUSHI
4j1y:A (TRP451) to (THR472) THE X-RAY CRYSTAL STRUCTURE OF HUMAN COMPLEMENT PROTEASE C1S ZYMOGEN | C4, C2, HYDROLYSIS, EXTRACELLULAR, HYDROLASE
4j1y:B (TRP451) to (THR472) THE X-RAY CRYSTAL STRUCTURE OF HUMAN COMPLEMENT PROTEASE C1S ZYMOGEN | C4, C2, HYDROLYSIS, EXTRACELLULAR, HYDROLASE
1e2v:A (ASN99) to (PRO129) N153Q MUTANT OF CYTOCHROME F FROM CHLAMYDOMONAS REINHARDTII | ELECTRON TRANSPORT, INTERNAL WATER CHAIN, PHOTOSYNTHETIC FUNCTION IMPAIRED
2d5h:D (PRO160) to (SER203) CRYSTAL STRUCTURE OF RECOMBINANT SOYBEAN PROGLYCININ A3B4 SUBUNIT, ITS COMPARISON WITH MATURE GLYCININ A3B4 SUBUNIT, RESPONSIBLE FOR HEXAMER ASSEMBLY | GLYCININ, SOYBEAN, GLOBULIN, 11S,SEED STORAGE PROTEIN, PLANT PROTEIN
2r6g:F (ASP185) to (GLY206) THE CRYSTAL STRUCTURE OF THE E. COLI MALTOSE TRANSPORTER | ABC TRANSPORTER, CATALYTIC INTERMEDIATE, E. COLI MALTOSE TRANSPORTER, MBP, MALTODEXTRIN BINDING PROTEIN, MALK, ATP BINDING CASSETTE, ATP- BINDING, HYDROLASE, INNER MEMBRANE, MEMBRANE, NUCLEOTIDE-BINDING, SUGAR TRANSPORT, TRANSMEMBRANE, HYDROLASE-TRANSPORT PROTEIN COMPLEX
2r9r:A (PHE38) to (THR56) SHAKER FAMILY VOLTAGE DEPENDENT POTASSIUM CHANNEL (KV1.2-KV2.1 PADDLE CHIMERA CHANNEL) IN ASSOCIATION WITH BETA SUBUNIT | POTASSIUM CHANNEL, VOLTAGE SENSOR, VOLTAGE DEPENDENT, ION CHANNEL, SHAKER, MEMBRANE PROTEIN, EUKARYOTIC, KV1.2, KV2.1, PADDLE CHIMERA CHANNEL, ION TRANSPORT, IONIC CHANNEL, NADP, PHOSPHORYLATION, POTASSIUM TRANSPORT, TRANSPORT, VOLTAGE-GATED CHANNEL, PROTEIN TRANSPORT, TRANSPORT PROTEIN
2ra0:A (GLN30) to (THR54) X-RAY STRUCTURE OF FXA IN COMPLEX WITH 7-FLUOROINDAZOLE | SERINE PROTEASE, BLOOD COAGULATION, CALCIUM, CLEAVAGE ON PAIR OF BASIC RESIDUES, EGF-LIKE DOMAIN, GAMMA- CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, HYDROXYLATION, POLYMORPHISM, ZYMOGEN
1qa0:A (GLN21) to (SER43) BOVINE TRYPSIN 2-AMINOBENZIMIDAZOLE COMPLEX | PROTEIN-INHIBITOR COMPLEX, S1 POCKET, SERINE PROTEASE, HYDROLASE
2dsz:A (THR286) to (GLN310) THREE DIMENSIONAL STRUCTURE OF A GOAT SIGNALLING PROTEIN SECRETED DURING INVOLUTION | SPG-40, NATIVE, INVOLUTION, SIGNALING PROTEIN
2e0a:A (GLN345) to (PRO376) CRYSTAL STRUCTURE OF HUMAN PYRUVATE DEHYDROGENASE KINASE 4 IN COMPLEX WITH AMPPNP | PDK4, KINASE, ATP-BINDING, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
3tu8:A (GLY170) to (GLN211) CRYSTAL STRUCTURE OF THE BURKHOLDERIA LETHAL FACTOR 1 (BLF1) | TOXIN, UNKNOWN FUNCTION
1ql7:A (GLN30) to (SER54) FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN | SERINE PROTEASE, HYDROLASE, SERINE PROTEINASE
3h31:A (LEU40) to (PRO62) STRUCTURE OF RHODOTHERMUS MARINUS HIPIP AT 1.0 A RESOLUTION | IRON-SULFUR PROTEIN, ELECTRON TRANSPORT, IRON, METAL-BINDING, TRANSPORT
1ewh:C (ASN99) to (PRO129) STRUCTURE OF CYTOCHROME F FROM CHLAMYDOMONAS REINHARDTII | BETA SANDWICH, HEME PROTEIN, ELECTRON TRANSPORT
1exh:A (SER3) to (PHE42) SOLUTION STRUCTURE OF A CELLULOSE BINDING DOMAIN FROM CELLULOMONAS FIMI BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY | CELLULOSE BINDING DOMAIN, CELLULOSE DEGRADATION
1ezq:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH RPR128515 | HYDROLASE
1f0u:A (GLN30) to (SER54) BOVINE TRYPSIN COMPLEXED WITH RPR128515 | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
2uuf:B (GLN30) to (THR54) THROMBIN-HIRUGEN BINARY COMPLEX AT 1.26A RESOLUTION | SERINE PROTEASE INHIBITOR, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, SERINE PROTEASE, THROMBIN, PROTEASE, SULFATION, ACUTE PHASE, HIGH RESOLUTION, DISEASE MUTATION, SERINE PROTEINASE, BLOOD COAGULATION, PROTEASE INHIBITOR, BLOOD CLOTTING, CLEAVAGE ON PAIR OF BASIC RESIDUES, HIRUGEN, KRINGLE, ZYMOGEN, SECRETED, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1f31:A (GLU1202) to (GLY1235) CRYSTAL STRUCTURE OF CLOSTRIDIUM BOTULINUM NEUROTOXIN B COMPLEXED WITH A TRISACCHARIDE | BOTULINUM, ZINC, METALLOPROTEASE, TRANSMEMBRANE, NEUROTOXIN, COMPLEX, GANGLIOSIDE
4jto:A (ARG57) to (SER84) CYSTEINE BOUND CYSTEINE DIOXYGENASE AT PH 8.0 IN THE PRESENCE OF CYS AND DITHIONITE | CUPIN FOLD, CYSTEINE TO CYSTEINE SULFINIC ACID CATALYSIS, CYTOSOL, OXIDOREDUCTASE
1faq:A (THR138) to (HIS173) RAF-1 CYSTEINE RICH DOMAIN, NMR, 27 STRUCTURES | TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, PROTO- ONCOGENE, ZINC, ATP-BINDING, PHORBOL-ESTER BINDING, SERINE/THREONINE PROTEIN KINASE COMPLEX
3u9a:H (GLN30) to (THR54) HUMAN THROMBIN IN COMPLEX WITH MI330 | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, HIRUDIN, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2eli:A (LYS19) to (HIS56) SOLUTION STRUCTURE OF THE SECOND PHORBOL ESTERS/DIACYLGLYCEROL BINDING DOMAIN OF HUMAN PROTEIN KINASE C ALPHA TYPE | PKC-ALPHA, PKC-A, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
4k1t:C (GLY17) to (LEU35) GLY-SER-SPLB PROTEASE FROM STAPHYLOCOCCUS AUREUS AT 1.60 A RESOLUTION | CHYMOTRYPSIN-LIKE FOLD, SERINE PROTEASE, EXTRACELLULAR, HYDROLASE
1r79:A (PRO27) to (HIS67) SOLUTION STRUCTURE OF THE C1 DOMAIN OF THE HUMAN DIACYLGLYCEROL KINASE DELTA | C1 DOMAIN, CYSTEIN-RICH ZINC BINDING DOMAIN, DIACYLGLYCEROL KINASE DELTA, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
1fmg:A (GLN30) to (SER54) CRYSTAL STRUCTURE OF PORCINE BETA TRYPSIN WITH 0.04% POLYDOCANOL | SERINE PROTEASE, HYDROLASE
3ufl:A (GLY13) to (GLY41) DISCOVERY OF PYRROLIDINE-BASED B-SECRETASE INHIBITORS: LEAD ADVANCEMENT THROUGH CONFORMATIONAL DESIGN FOR MAINTENANCE OF LIGAND BINDING EFFICIENCY | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1rh7:F (THR23) to (THR45) CRYSTAL STRUCTURE OF RESISTIN-LIKE BETA | HORMONE; GLUCOSE UPTAKE; RESISTIN/FIZZ FAMILY, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, HORMONE/GROWTH FACTOR COMPLEX
4yx1:B (VAL40) to (ILE65) SPAO(SPOA2) | TYPE III SECRETION SYSTEM, PROTEIN TRANSPORT
4yyo:A (ARG57) to (SER84) RESTING STATE OF RAT CYSTEINE DIOXYGENASE C164S VARIANT | OXIDOREDUCTASE
1g2m:A (GLN30) to (THR54) FACTOR XA INHIBITOR COMPLEX | BLOOD COAGULATION, FACTOR XA, INHIBITOR COMPLEXES, SERINE PROTEINASE, BLOOD COAGULATION CASCADE, HYDROLASE
3urc:A (ILE31) to (ALA55) T181G MUTANT OF ALPHA-LYTIC PROTEASE | SERINE PROTEASE, HYDROLASE
4z4r:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 300MM FUCOSE | FUCOSE, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
4z4r:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF GII.10 P DOMAIN IN COMPLEX WITH 300MM FUCOSE | FUCOSE, NOROVIRUS, PROTRUDING DOMAIN, VIRAL PROTEIN
3hpt:B (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN FXA IN COMPLEX WITH (S)-2-CYANO-1-(2- METHYLBENZOFURAN-5-YL)-3-(2-OXO-1-(2-OXO-2-(PYRROLIDIN-1-YL)ETHYL) AZEPAN-3-YL)GUANIDINE | SERINE PROTEASE, HYDROLASE, EPIDERMAL GROWTH FACTOR LIKE DOMAIN, BLOOD COAGULATION FACTOR, CLEAVAGE ON PAIR OF BASIC RESIDUES, EGF- LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROXYLATION, ZYMOGEN, BLOOD CLOTTING, BLOOD COAGULATION, DISULFIDE BOND, PROTEASE, SECRETED
3hpt:D (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN FXA IN COMPLEX WITH (S)-2-CYANO-1-(2- METHYLBENZOFURAN-5-YL)-3-(2-OXO-1-(2-OXO-2-(PYRROLIDIN-1-YL)ETHYL) AZEPAN-3-YL)GUANIDINE | SERINE PROTEASE, HYDROLASE, EPIDERMAL GROWTH FACTOR LIKE DOMAIN, BLOOD COAGULATION FACTOR, CLEAVAGE ON PAIR OF BASIC RESIDUES, EGF- LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROXYLATION, ZYMOGEN, BLOOD CLOTTING, BLOOD COAGULATION, DISULFIDE BOND, PROTEASE, SECRETED
2fje:A (ARG173) to (ALA207) ADENOSINE-5-PHOSPHOSULFATE REDUCTASE OXIDIZED STATE | APS REDUCTASE, SULFUR CYCLE, OXIDOREDUCTASE
2fje:C (ARG2173) to (ALA2207) ADENOSINE-5-PHOSPHOSULFATE REDUCTASE OXIDIZED STATE | APS REDUCTASE, SULFUR CYCLE, OXIDOREDUCTASE
2fkb:B (HIS37) to (THR70) CRYSTAL STRUCTURE OF A PUTATIVE ENZYME (POSSIBLE NUDIX HYDROLASE) FROM ESCHERICHIA COLI K12 | PUTATIVE PROTEIN, MAD, STRUCTURAL GENOMICS, ESCHERICHIA COLI K12, PUTATIVE NUDIX HYDROLASE, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
2fkb:C (HIS37) to (THR70) CRYSTAL STRUCTURE OF A PUTATIVE ENZYME (POSSIBLE NUDIX HYDROLASE) FROM ESCHERICHIA COLI K12 | PUTATIVE PROTEIN, MAD, STRUCTURAL GENOMICS, ESCHERICHIA COLI K12, PUTATIVE NUDIX HYDROLASE, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
4z7i:A (GLY615) to (ILE654) CRYSTAL STRUCTURE OF INSULIN REGULATED AMINOPEPTIDASE IN COMPLEX WITH LIGAND | AMINOPEPTIDASE, ANTIGEN PRESENTATION, TRANSITION-STATE ANALOGUE, ENZYME INHIBITOR, HYDROLASE, IRAP
3uy9:A (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uy9:C (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uy9:D (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uy9:E (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uy9:F (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uy9:G (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uy9:I (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uy9:J (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uy9:K (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uy9:L (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uy9:M (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uy9:N (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uy9:O (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uy9:P (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217PHE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3uze:C (THR305) to (ASP341) CRYSTAL STRUCTURE OF THE DENGUE VIRUS SEROTYPE 3 ENVELOPE PROTEIN DOMAIN III IN COMPLEX WITH THE VARIABLE DOMAINS OF MAB 4E11 | DENGUE ANTIBODY NEUTRALIZATION, IMMUNE SYSTEM
3uze:D (THR305) to (ASP341) CRYSTAL STRUCTURE OF THE DENGUE VIRUS SEROTYPE 3 ENVELOPE PROTEIN DOMAIN III IN COMPLEX WITH THE VARIABLE DOMAINS OF MAB 4E11 | DENGUE ANTIBODY NEUTRALIZATION, IMMUNE SYSTEM
3v0b:B (ASP866) to (ASN891) 3.9 ANGSTROM CRYSTAL STRUCTURE OF BONT/AI IN COMPLEX WITH NTNHA | VHH FREE INLOCKED COMPLEX, BOTULINUM NEUROTOXIN, TOXIN
3v11:A (GLY31) to (HIS97) STRUCTURE OF THE TERNARY INITIATION COMPLEX AIF2:GDPNP:METHIONYLATED INITIATOR TRNA | GTP BINDING MODULE, INITIATOR TRNA CARRIER, GTP AND TRNA, TRANSLATION-RNA COMPLEX
3v8s:C (GLY193) to (ASP232) HUMAN RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH INDAZOLE DERIVATIVE (COMPOUND 18) | KINASE, DIMERIZATION, MYOSIN, TRANSFERASE, INHIBITOR, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2g3p:B (ASN19) to (GLY42) STRUCTURE OF THE N-TERMINAL TWO DOMAINS OF THE INFECTIVITY PROTEIN G3P OF FILAMENTOUS PHAGE FD | INFECTION, FILAMENTOUS PHAGE, PILUS BINDING, BETA BARREL, CONFORMATIONAL CHANGE, VIRAL PROTEIN
3vb3:B (VAL18) to (PRO39) CRYSTAL STRUCTURE OF SARS-COV 3C-LIKE PROTEASE IN APO FORM | HYDROLASE
2g5n:A (GLN21) to (SER43) INDOLE-AMIDINE COMPLEXES WITH BOVINE TRYPSIN | TRYPSIN AMIDINE INDOLE INHIBITION, HYDROLASE
4kwj:A (ARG57) to (SER84) RESTING STATE OF RAT CYSTEINE DIOXYGENASE | NON-HEME, MONO-IRON, CUPIN, DIOXYGENASE, CYSTEINE-TYROSINE CROSSLINK, OXIDOREDUCTASE
2gb5:A (HIS103) to (ASP138) CRYSTAL STRUCTURE OF NADH PYROPHOSPHATASE (EC 3.6.1.22) (1790429) FROM ESCHERICHIA COLI K12 AT 2.30 A RESOLUTION | 1790429, NADH PYROPHOSPHATASE (EC 3.6.1.22), STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, HYDROLASE
2vwo:A (GLN30) to (THR54) AMINOPYRROLIDINE FACTOR XA INHIBITOR | HYDROLASE, CATION, PLASMA, CALCIUM, ZYMOGEN, PROTEASE, INHIBITOR, POLYMORPHISM, GLYCOPROTEIN, GAMMA-CARBOXYGLUTAMIC ACID, BLOOD CLOTTING, COAGULATION FACTOR, HYDROXYLATION, SERINE PROTEASE, EGF-LIKE DOMAIN, CLEAVAGE ON PAIR OF BASIC RESIDUES
2gh2:A (ARG57) to (SER84) 1.5 A RESOLUTION R. NORVEGICUS CYSTEINE DIOXYGENASE STRUCTURE CRYSTALLIZED IN THE PRESENCE OF CYSTEINE | THIOETHER, CYSTEINYL-TYROSINE, CUPIN, BETA-SANDWICH, TETRAHEDRAL IRON COORDINATION, OXIDOREDUCTASE
3vin:A (SER457) to (GLU478) CRYSTAL STRUCTURE OF BETA-GLUCOSIDASE FROM TERMITE NEOTERMES KOSHUNENSIS IN COMPLEX WITH A NEW GLUCOPYRANOSIDIC PRODUCT | CELLULASES, GLYCOSYL HYDROLASE, HYDROLASE
3vio:A (SER457) to (GLU478) CRYSTAL STRUCTURE OF BETA-GLUCOSIDASE FROM TERMITE NEOTERMES KOSHUNENSIS IN COMPLEX WITH A NEW GLUCOPYRANOSIDIC PRODUCT | CELLULASES, GLYCOSYL HYDROLASE, HYDROLASE
3vip:A (SER457) to (GLU478) CRYSTAL STRUCTURE OF BETA-GLUCOSIDASE FROM TERMITE NEOTERMES KOSHUNENSIS IN COMPLEX WITH A NEW GLUCOPYRANOSIDIC PRODUCT | CELLULASES, GLYCOSYL HYDROLASE, HYDROLASE
1t3c:B (LEU18) to (PRO42) CLOSTRIDIUM BOTULINUM TYPE E CATALYTIC DOMAIN E212Q MUTANT | CLOSTRIDIUM BOTULINUM, CATALYTIC DOMAIN, E212Q MUTANT, LIGHT CHAIN, HYDROLASE, TOXIN
1t7j:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INHIBITOR AMPRENAVIR IN COMPLEX WITH A MULTI-DRUG RESISTANT VARIANT OF HIV-1 PROTEASE (L63P/V82T/I84V) | HIV-1 PROTEASE, DRUG RESITANCE, THERMODYNAMICS, SUBSTRATE ENVELOPE, HYDROLASE
2w2w:A (LYS7) to (SER37) PLCG2 SPLIT PLECKSTRIN HOMOLOGY (PH) DOMAIN | HYDROLASE, PHOSPHOLIPASE C, PHOSPHOINOSITIDES, RHO GTPASES, RAC, SH2 DOMAIN, SH3 DOMAIN
2w2w:C (LYS7) to (SER37) PLCG2 SPLIT PLECKSTRIN HOMOLOGY (PH) DOMAIN | HYDROLASE, PHOSPHOLIPASE C, PHOSPHOINOSITIDES, RHO GTPASES, RAC, SH2 DOMAIN, SH3 DOMAIN
4l9g:A (LEU88) to (ARG121) STRUCTURE OF PPSR N-Q-PAS1 FROM RB. SPHAEROIDES | PAS DOMAIN, PER-ARNT-SIM, OLIGOMERIZATION, APPA, TRANSCRIPTION
1hbm:C (ARG174) to (GLY202) METHYL-COENZYME M REDUCTASE ENZYME PRODUCT COMPLEX | METHANOGENESIS, BIOLOGICAL METHANOGENESIS, NI-ENZYME, OXIDOREDUCTASE
2gwd:A (THR373) to (GLY388) CRYSTAL STRUCTURE OF PLANT GLUTAMATE CYSTEINE LIGASE IN COMPLEX WITH MG2+ AND L-GLUTAMATE | DISULFIDE BRIDGES, GLUTATHIONE BIOSYNTHESIS, BETA-HAIRPIN, REDOX REGULATION, LIGASE
1tfq:A (GLY288) to (ASP309) NMR STRUCTURE OF AN ANTAGONISTS OF THE XIAP-CASPASE-9 INTERACTION COMPLEXED TO THE BIR3 DOMAIN OF XIAP | COMPLEX, LIGAND-PROTEIN, APOPTOSIS, BIR, XIAP
4lg4:E (VAL26) to (GLN57) STRUCTURAL BASIS FOR AUTOACTIVATION OF HUMAN MST2 KINASE AND ITS REGULATION BY RASSF5 | HIPPO, MST AUTOACTIVATION, DIMERIZATION, SIGNALING PROTEIN
1hj9:A (GLN30) to (SER54) ATOMIC RESOLUTION STRUCTURES OF TRYPSIN PROVIDE INSIGHT INTO STRUCTURAL RADIATION DAMAGE | HYDROLASE, RADIATION DAMAGE, DISULPHID BOND BREAKAGE, TRYPSIN, ATOMIC RESOLUTION, SERINE PROTEINASE
2h9t:H (GLN30) to (THR54) CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN IN COMPLEX WITH SURAMIN | THROMBIN, COAGULATION FACTOR II, SURAMIN, INHIBITOR, HYDROLASE
2hc8:A (SER268) to (ARG304) STRUCTURE OF THE A. FULGIDUS COPA A-DOMAIN | COPPER, ATPASE, COPA, COPB, ACTUATOR, TRANSPORT PROTEIN
3iw4:B (ASP338) to (LYS371) CRYSTAL STRUCTURE OF PKC ALPHA IN COMPLEX WITH NVP-AEB071 | KINASE, ATP-BINDING, CELL MEMBRANE, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PHORBOL-ESTER BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, ZINC-FINGER
1hpg:A (GLY29) to (ALA55) A GLUTAMIC ACID SPECIFIC SERINE PROTEASE UTILIZES A NOVEL HISTIDINE TRIAD IN SUBSTRATE BINDING | SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2hgo:A (SER5) to (ALA23) NMR STRUCTURE OF CASSIICOLIN | TOXIN, DISULFIDE BRIDGE, GLYCOPROTEIN
1hrt:H (GLN30) to (THR54) THE STRUCTURE OF A COMPLEX OF BOVINE ALPHA-THROMBIN AND RECOMBINANT HIRUDIN AT 2.8 ANGSTROMS RESOLUTION | HYDROLASE(SERINE PROTEINASE)
1twc:K (LYS18) to (HIS40) RNA POLYMERASE II COMPLEXED WITH GTP | TRANSCRIPTION, MRNA, MULTIPROTEIN COMPLEX, MOLECULAR MACHINE, ZINC MOTIFS
3iyl:W (THR1133) to (VAL1165) ATOMIC CRYOEM STRUCTURE OF A NONENVELOPED VIRUS SUGGESTS HOW MEMBRANE PENETRATION PROTEIN IS PRIMED FOR CELL ENTRY | NON-ENVELOPED VIRUS, MEMBRANE PENETRATION PROTEIN, AUTOCLEAVAGE, MYRISTOL GROUP, ICOSAHEDRAL VIRUS, VIRUS
1tx6:C (GLN30) to (SER54) TRYPSIN:BBI COMPLEX | ANTICARCINOGENIC ACTIVITY, DOUBLE-HEADED INHIBITOR, GENE DUPLICATION, MONOCOTYLEDONOUS PLANT, INHIBITORY LOOP, HYDROLASE/PROTEIN BINDING COMPLEX
1hyl:B (TYR29) to (THR54) THE 1.8 A STRUCTURE OF COLLAGENASE FROM HYPODERMA LINEATUM | HYDROLASE (SERINE PROTEASE)
2hrr:A (PRO1023) to (LEU1051) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 (HCE1) IN COVALENT COMPLEX WITH THE NERVE AGENT TABUN (GA) | HYDROLASE, CARBOXYLESTERASE, TABUN
2hrr:B (PRO2023) to (GLY2052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 (HCE1) IN COVALENT COMPLEX WITH THE NERVE AGENT TABUN (GA) | HYDROLASE, CARBOXYLESTERASE, TABUN
2hrr:C (PRO3023) to (GLY3052) CRYSTAL STRUCTURE OF HUMAN LIVER CARBOXYLESTERASE 1 (HCE1) IN COVALENT COMPLEX WITH THE NERVE AGENT TABUN (GA) | HYDROLASE, CARBOXYLESTERASE, TABUN
5a2m:H (GLN30) to (THR54) THROMBIN INHIBITOR | HYDROLASE, HYDROLASE INHIBITOR COMPLEX, SERINE PROTEASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, BLOOD CLOTTING INHIBITOR, THROMBIN INHIBITOR, PREORGANIZATION, GLYCOSYLATION, BLOOD
1iau:A (TYR29) to (THR54) HUMAN GRANZYME B IN COMPLEX WITH AC-IEPD-CHO | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ucu:A (LEU220) to (ASP250) R-TYPE STRAIGHT FLAGELLAR FILAMENT MADE OF FULL-LENGTH FLAGELLIN | FLAGELLIN, FLAGELLAR FILAMENT, CRYO-ELECTRON MICROSCOPY, HELICAL RECONSTRUCTION, STRUCTURAL PROTEIN
3w6q:A (THR558) to (ALA603) CRYSTAL STRUCTURE OF MELB APO-PROTYROSINASE FROM ASPERUGILLUS ORYZAE | FOUR HELIX BUNDLE, METAL BINDING PROTEIN, OXIDOREDUCTASE
3w6q:B (THR558) to (ALA603) CRYSTAL STRUCTURE OF MELB APO-PROTYROSINASE FROM ASPERUGILLUS ORYZAE | FOUR HELIX BUNDLE, METAL BINDING PROTEIN, OXIDOREDUCTASE
5a7g:A (PRO23) to (GLY52) COMPARISON OF THE STRUCTURE AND ACTIVITY OF GLYCOSYLATED AND AGLYCOSYLATED HUMAN CARBOXYLESTERASE 1 | HYDROLASE, ESTERASE
2i6q:A (TRP460) to (THR484) COMPLEMENT COMPONENT C2A | SERINE PROTEASE DOMAIN, VON WILLEBRAND FACTOR-A DOMAIN, HYDROLASE
1iqj:A (GLN30) to (THR54) HUMAN COAGULATION FACTOR XA IN COMPLEX WITH M55124 | HYDROLASE, SERINE PROTEASE, BLOOD COAGULATION FACTOR, COMPLEX
1iry:A (SER4) to (GLY34) SOLUTION STRUCTURE OF THE HMTH1, A NUCLEOTIDE POOL SANITIZATION ENZYME | NUDIX MOTIF(G37-L59), HYDROLASE
3j1p:B (GLY510) to (GLY537) ATOMIC MODEL OF RABBIT HEMORRHAGIC DISEASE VIRUS | ICOSAHEDRAL VIRUS, CALICIVIRUS, LAGOVIRUS, VIRUS
5aag:A (ASP132) to (PHE165) AURORA A KINASE BOUND TO AN IMIDAZOPYRIDINE INHIBITOR (14B) | TRANSFERASE, AURORA-A, IMIDAZOPYRIDINE, AURORA KINASE, INHIBITOR
2if7:A (ILE111) to (LEU147) CRYSTAL STRUCTURE OF NTB-A | NTB-A, SLAM6, LY108, HOMOPHILIC RECEPTOR, IMMUNE SYSTEM
4mcx:F (GLY62) to (ILE85) P. VULGARIS HIGBA STRUCTURE, CRYSTAL FORM 2 | BACTERIAL TOXINS, BIOFILMS, CELL METABOLISM, ENERGY METABOLISM, HELIX-TURN-HELIX TRANSCRIPTION FACTORS, MICROBIAL PATHOGENESIS, STRESS RESPONSE, STRINGENT RESPONSE, TRANSCRIPTION REPRESSOR, TRANSLATION CONTROL, ANTITOXIN, TOXIN
4md9:D (GLN117) to (THR145) CRYSTAL STRUCTURE OF SYMMETRIC CK2 HOLOENZYME WITH MUTATED ALPHA SUBUNIT (F121E TRUNCATED AT AA 336) | PROTEIN SERINE/THREONINE KINASE, TRANSFERASE
4md9:I (GLN117) to (THR145) CRYSTAL STRUCTURE OF SYMMETRIC CK2 HOLOENZYME WITH MUTATED ALPHA SUBUNIT (F121E TRUNCATED AT AA 336) | PROTEIN SERINE/THREONINE KINASE, TRANSFERASE
4md9:N (GLN117) to (THR145) CRYSTAL STRUCTURE OF SYMMETRIC CK2 HOLOENZYME WITH MUTATED ALPHA SUBUNIT (F121E TRUNCATED AT AA 336) | PROTEIN SERINE/THREONINE KINASE, TRANSFERASE
1v2q:T (GLN30) to (SER54) TRYPSIN INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN VARIANT X(SSWI)BT.B4 | SERINE PROTEASE, HYDROLASE, SERINE PROTEINASE
2ivf:C (ARG113) to (MET141) ETHYLBENZENE DEHYDROGENASE FROM AROMATOLEUM AROMATICUM | ANAEROBIC HYDROCARBON DEGRADATION, MOCO, FE/S CLUSTER, MO- BISMGD ENZYME, DMSO REDUCTASE FAMILY, OXIDOREDUCTASE
3wo2:A (THR45) to (CYS76) CRYSTAL STRUCTURE OF HUMAN INTERLEUKIN-18 | BETA TREFOIL FOLD, IL-1 SUPERFAMILY, IMMUNITY, INFLAMMATION, AUTOIMMUNITY, ALLERGY, INTERLEUKIN-18 RECEPTOR ALPHA, INTERLEUKIN-18 RECEPTOR BETA, SERUM, IMMUNE SYSTEM
3wo2:D (THR45) to (CYS76) CRYSTAL STRUCTURE OF HUMAN INTERLEUKIN-18 | BETA TREFOIL FOLD, IL-1 SUPERFAMILY, IMMUNITY, INFLAMMATION, AUTOIMMUNITY, ALLERGY, INTERLEUKIN-18 RECEPTOR ALPHA, INTERLEUKIN-18 RECEPTOR BETA, SERUM, IMMUNE SYSTEM
3wol:A (VAL64) to (ASN84) CRYSTAL STRUCTURE OF THE DAP BII DIPEPTIDE COMPLEX I | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE
3wol:A (ASP195) to (ALA240) CRYSTAL STRUCTURE OF THE DAP BII DIPEPTIDE COMPLEX I | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE
3wol:B (VAL64) to (ASN84) CRYSTAL STRUCTURE OF THE DAP BII DIPEPTIDE COMPLEX I | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE
3wol:B (ASP195) to (ALA240) CRYSTAL STRUCTURE OF THE DAP BII DIPEPTIDE COMPLEX I | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE
3won:B (VAL64) to (ASN84) CRYSTAL STRUCTURE OF THE DAP BII DIPEPTIDE COMPLEX III | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE
3won:B (ASP195) to (ALA240) CRYSTAL STRUCTURE OF THE DAP BII DIPEPTIDE COMPLEX III | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE
2xc0:A (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH A PYRROLIDINE-3,4-DICARBOXYLIC ACID INHIBITOR | BLOOD CLOTTING, COAGULATION FACTOR, HYDROLASE, HYDROXYLATION, SERINE PROTEASE, ZYMOGEN
2xc4:A (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH A PYRROLIDINE-3,4-DICARBOXYLIC ACID INHIBITOR | BLOOD CLOTTING, COAGULATION FACTOR, EGF-LIKE DOMAIN, GAMMA- CARBOXYGLUTAMIC ACID, HYDROLASE, HYDROXYLATION, ZYMOGEN
1vcq:B (CYS119) to (PRO143) SEMLIKI FOREST VIRUS CAPSID PROTEIN (CRYSTAL FORM II) | VIRUS COAT PROTEIN, POLYPROTEIN, TRANSMEMBRANE, GLYCOPROTEIN, NUCLEOCAPSID PROTEIN, VIRAL PROTEIN
1vit:H (GLN30) to (LEU53) THROMBIN:HIRUDIN 51-65 COMPLEX | COMPLEX (SERINE PROTEASE-INHIBITOR), HYDROLASE, SERINE PROTEASE, BLOOD COAGULATION, COMPLEX (SERINE PROTEASE-INHIBITOR) COMPLEX
1jpa:B (CYS628) to (LEU663) CRYSTAL STRUCTURE OF UNPHOSPHORYLATED EPHB2 RECEPTOR TYROSINE KINASE AND JUXTAMEMBRANE REGION | RECEPTOR TYROSINE KINASE, AUTOINHIBITED, UNPHOSPHORYLATED, JUXTAMEMBRANE, TRANSFERASE
3wsy:A (LEU220) to (MET243) SORLA VPS10P DOMAIN IN COMPLEX WITH ITS OWN PROPEPTIDE FRAGMENT | BETA-PROPELLER, RECEPTOR, PROTEIN BINDING
3wvq:C (ARG250) to (PRO283) STRUCTURE OF ATP GRASP PROTEIN | ATP GRASP DOMAIN, LIGASE, BIOSYNTHETIC PROTEIN
4mzf:B (VAL137) to (TYR170) CRYSTAL STRUCTURE OF HUMAN SPINDLIN1 BOUND TO HISTONE H3(K4ME3-R8ME2A) PEPTIDE | WNT SIGNAL, HISTONE H3, NUCLEAR, GENE REGULATION
5b4n:B (GLY149) to (ASP186) STRUCTURE ANALYSIS OF FUNCTION ASSOCIATED LOOP MUTANT OF SUBSTRATE RECOGNITION DOMAIN OF FBS1 UBIQUITIN LIGASE | SCF E3 UBIQUITIN LIGASE, F-BOX PROTEIN, GLYCOPROTEINS, SEQUENCE- STRUCTURE RELATIONSHIP, LIGASE
5bn3:A (LYS111) to (VAL146) STRUCTURE OF A UNIQUE ATP SYNTHASE NEQA-NEQB IN COMPLEX WITH ADP FROM NANOARCHEAUM EQUITANS | ATP SYNTHASE, NANOARCHEAUM EQUITANS, CATALYTIC CORE, HYDROLASE
5bt2:A (GLY103) to (SER134) MECP2 MBD DOMAIN (A140V) IN COMPLEX WITH METHYLATED DNA | A/T RUN, MECP2, HYDRATION SPINE, METHYLATED DNA, DNA BINDING PROTEIN- DNA COMPLEX
1wcm:I (GLU82) to (SER112) COMPLETE 12-SUBUNIT RNA POLYMERASE II AT 3.8 ANG | DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, DNA-DEPENDENT RNA POLYMERASE, CELLULAR RNA POLYMERASE, MULTISUBUNIT CO, METAL- BINDING, NUCLEAR PROTEIN, REPEAT, TRANSCRIPTION, PHOSPHORYLATION, TRANSFERASE, ZINC, ZINC-FINGER
2jn9:A (THR49) to (THR89) NMR SOLUTION STRUCTURE OF YKVR PROTEIN FROM BACILLUS SUBTILIS: NESG TARGET SR358 | YKVR, SR358, BACILLUS SUBTILIS, NESG, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, UNKNOWN FUNCTION
2k03:A (HIS25) to (ASP52) STRUCTURE OF SDF1 IN COMPLEX WITH THE CXCR4 N-TERMINUS CONTAINING A SULFOTYROSINE AT POSTITION 21 | STROMAL CELL DERIVED FACTOR-1, SDF1-ALPHA, CXCL12, CXCR4, CHEMOKINE, SULFOTYROSINE, LOCKED DIMER, ALTERNATIVE SPLICING, CHEMOTAXIS, CYTOKINE, GROWTH FACTOR, SECRETED, G- PROTEIN COUPLED RECEPTOR, GLYCOPROTEIN, HOST-VIRUS INTERACTION, MEMBRANE, RECEPTOR, SULFATION, TRANSDUCER, TRANSMEMBRANE
3zm8:A (GLY100) to (PRO129) CRYSTAL STRUCTURE OF PODOSPORA ANSERINA GH26-CBM35 BETA-(1,4)-MANNANASE | HYDROLASE, GLYCOSYL HYDROLASE, CAZY, GH5
3zmn:B (VAL43) to (ALA87) VP17, A CAPSID PROTEIN OF BACTERIOPHAGE P23-77 | VIRAL PROTEIN
2y82:A (GLN30) to (THR54) STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: PYRROLIDIN-2-ONES WITH AMINOINDANE AND PHENYLPYRROLIDINE P4 MOTIFS | BLOOD CLOTTING, HYDROLASE, SERINE PROTEASE, BLOOD COAGULATION
2ya4:B (ALA437) to (ARG461) CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE NANA (TIGR4) | HYDROLASE, SIALIDASE
1x2t:A (VAL66) to (ILE117) CRYSTAL STRUCTURE OF HABU IX-BP AT PH 6.5 | HETERODIMER, DOMAIN SWAPPING, C-TYPE LECTIN-LIKE PROTEIN, PROTEIN BINDING
2mjp:A (ASP109) to (GLU158) STRUCTURE-BASED IDENTIFICATION OF THE BIOCHEMICAL FUNCTION OF A HYPOTHETICAL PROTEIN FROM METHANOCOCCUS JANNASCHII:MJ0226 | STRUCTURAL GENOMICS, PYROPHOSPHATASE, HYPERTHERMAL PROTEIN, BSGC STRUCTURE FUNDED BY NIH, PROTEIN STRUCTURE INITIATIVE, PSI, BERKELEY STRUCTURAL GENOMICS CENTER
1x75:C (LYS4) to (ALA37) CCDB:GYRA14 COMPLEX | GYRASE, CCDB, TOPOISOMERASE, PLASMID ADDICTION, TA SYSTEM, BACTERIAL CELL DEATH, ISOMERASE/SIGNALING PROTEIN COMPLEX
1kta:A (LEU226) to (TRP247) HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE : THREE DIMENSIONAL STRUCTURE OF THE ENZYME IN ITS PYRIDOXAMINE PHOSPHATE FORM. | FOLD TYPE IV, TRANSFERASE
2mx4:A (ASP33) to (ARG56) NMR STRUCTURE OF PHOSPHORYLATED 4E-BP2 | PHOSPHORYLATION, INTRINSIC DISORDER, TRANSLATION, PROTEIN BINDING, TRANSLATION,PROTEIN BINDING
4o1s:A (ASP145) to (ALA170) CRYSTAL STRUCTURE OF TVOVMA INTEIN | SPLICING
1xfn:A (ASN89) to (VAL125) NMR STRUCTURE OF THE GROUND STATE OF THE PHOTOACTIVE YELLOW PROTEIN LACKING THE N-TERMINAL PART | PAS DOMAIN, SIGNALING PROTEIN
3k1w:B (ASN5) to (THR39) NEW CLASSES OF POTENT AND BIOAVAILABLE HUMAN RENIN INHIBITORS | RENIN, PROTEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, POLYMORPHISM, SECRETED, ZYMOGEN
2z54:A (PRO9) to (GLU34) THE INFLUENCE OF I47A MUTATION ON REDUCED SUSCEPTIBILITY TO THE PROTEASE INHIBITOR LOPINAVIR | COMPLEX (ASPARTIC PROTEASE/INHIBITOR), ASPARTIC PROTEASE, RESISTANT STRAIN, HYDROLASE
2z54:B (PRO9) to (GLU34) THE INFLUENCE OF I47A MUTATION ON REDUCED SUSCEPTIBILITY TO THE PROTEASE INHIBITOR LOPINAVIR | COMPLEX (ASPARTIC PROTEASE/INHIBITOR), ASPARTIC PROTEASE, RESISTANT STRAIN, HYDROLASE
4a3k:B (THR1170) to (HIS1195) RNA POLYMERASE II INITIAL TRANSCRIBING COMPLEX WITH A 7NT DNA-RNA HYBRID | TRANSCRIPTION, TRANSCRIPTION INITIATION
4a59:A (GLN64) to (ASP96) CRYSTAL STRUCTURE OF TOXOPLASMA GONDII NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3 (NTPDASE3) IN COMPLEX WITH AMP | HYDROLASE, NTPDASE
1xka:C (GLN30) to (THR54) FACTOR XA COMPLEXED WITH A SYNTHETIC INHIBITOR FX-2212A,(2S)-(3'- AMIDINO-3-BIPHENYLYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID | BLOOD COAGULATION FACTOR, SERINE PROTEINASE, EPIDERMAL GROWTH FACTOR LIKE DOMAIN
2z9l:A (VAL18) to (PRO39) COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH JMF1586 | COMPLEX, HYDROLASE
2zez:C (TYR22) to (GLY49) FAMILY 16 CARBOHYDRATE BINDING MODULE-2 | FAMILY 16 CARBOHYDRATE BINDING MODULE-2, GLYCOSIDASE, HYDROLASE
4om9:A (GLY449) to (HIS474) X-RAY CRYSTAL STRUCTURE OF THE PASSENGER DOMAIN OF PLASMID ENCODED TOXIN, AN AUTROTANSPORTER ENTEROTOXIN FROM ENTEROAGGREGATIVE ESCHERICHIA COLI (EAEC) | BETA-HELIX, PEPTIDASE, ALPHA-FODRIN, HYDROLASE, EAEC, PLASMID ENCODED TOXIN(PET)
3kai:A (PRO9) to (TRP34) STRUCTURE-GUIDED DESIGN OF ALPHA-AMINO ACID-DERIVED PIN1 INHIBITORS | SBDD, PPIASE, ISOMERASE, ROTAMASE, SMALL MOLECULE, PROLINE DIRECTED KINASE, CELL CYCLE, ONCOGENIC TRANSFORMATION, NUCLEUS, PHOSPHOPROTEIN
2zg3:A (PRO151) to (GLY187) CRYSTAL STRUCTURE OF TWO N-TERMINAL DOMAINS OF NATIVE SIGLEC-5 IN COMPLEX WITH 3'-SIALYLLACTOSE | SIGLEC-5 INHIBITORY RECEPTOR, TWO-DOMAIN STRUCTURE, V-SET, C2-SET, IG-LIKE DOMAIN, SIALIC ACID, 3'-SIALYLLACTOSE COMPLEX, CELL ADHESION, GLYCOPROTEIN, IMMUNOGLOBULIN DOMAIN, LECTIN, MEMBRANE, POLYMORPHISM, TRANSMEMBRANE, IMMUNE SYSTEM/CARBOHYDRATE BINDING PROTEIN COMPLEX
2zgc:A (MET15) to (THR38) CRYSTAL STRUCTURE OF ACTIVE HUMAN GRANZYME M | SERINE PROTEASE, CYTOLYSIS, GLYCOPROTEIN, HYDROLASE, SECRETED, ZYMOGEN
2zi2:H (GLN30) to (THR54) THROMBIN INHIBITION | BLOOD CLOTTING, HYDROLASE INHIBITORS, ACUTE PHASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, GAMMA- CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, KRINGLE, PROTEASE, SECRETED, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1m3d:A (ALA115) to (TRP138) STRUCTURE OF TYPE IV COLLAGEN NC1 DOMAINS | BASEMENT MEMBRANE, TYPE IV COLLAGEN, NC1 DOMAIN, NETWORK ASSEMBLY, 3D DOMAIN SWAPPING, BR-MAD, STRUCTURAL PROTEIN
1m3d:G (ALA115) to (TRP138) STRUCTURE OF TYPE IV COLLAGEN NC1 DOMAINS | BASEMENT MEMBRANE, TYPE IV COLLAGEN, NC1 DOMAIN, NETWORK ASSEMBLY, 3D DOMAIN SWAPPING, BR-MAD, STRUCTURAL PROTEIN
1m3d:H (MET116) to (TRP138) STRUCTURE OF TYPE IV COLLAGEN NC1 DOMAINS | BASEMENT MEMBRANE, TYPE IV COLLAGEN, NC1 DOMAIN, NETWORK ASSEMBLY, 3D DOMAIN SWAPPING, BR-MAD, STRUCTURAL PROTEIN
4oqa:A (GLN301) to (GLN326) STRUCTURE OF HUMAN PARP-1 BOUND TO A DNA DOUBLE STRAND BREAK IN COMPLEX WITH (2Z)-2-(2,4-DIHYDROXYBENZYLIDENE)-3-OXO-2,3-DIHYDRO-1- BENZOFURAN-7-CARBOXAMIDE | ZINC FINGER, DNA BINDING, PARP, POLYMERASE, DNA REPAIR, POLY(ADP- RIBOSYL)ATION, TRANSFERASE-DNA-TRANSFERASE INHIBITOR COMPLEX
4oqa:D (GLN301) to (GLN326) STRUCTURE OF HUMAN PARP-1 BOUND TO A DNA DOUBLE STRAND BREAK IN COMPLEX WITH (2Z)-2-(2,4-DIHYDROXYBENZYLIDENE)-3-OXO-2,3-DIHYDRO-1- BENZOFURAN-7-CARBOXAMIDE | ZINC FINGER, DNA BINDING, PARP, POLYMERASE, DNA REPAIR, POLY(ADP- RIBOSYL)ATION, TRANSFERASE-DNA-TRANSFERASE INHIBITOR COMPLEX
2zr6:A (PRO9) to (TRP34) CRYSTAL STRUCTURE OF A MUTANT PIN1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE | PIN1 MUTANT (R14A), CELL CYCLE, ISOMERASE, NUCLEUS, PHOSPHOPROTEIN, ROTAMASE
2zt9:C (ASP100) to (PRO130) CRYSTAL STRUCTURE OF THE CYTOCHROME B6F COMPLEX FROM NOSTOC SP. PCC 7120 | PHOTOSYNTHESIS, CYTOCHROME B6F COMPLEX, HEME B,2FE-2S PROTEIN, CYTOCHROME F
1y14:B (GLY36) to (PRO81) CRYSTAL STRUCTURE OF YEAST SUBCOMPLEX OF RPB4 AND RPB7 | TRANSFERASE
4owk:B (LYS419) to (LEU441) CRYSTAL STRUCTURE OF THE VIBRIO VULNIFICUS HEMOLYSIN/CYTOLYSIN BETA- TREFOIL LECTIN WITH N-ACETYL-D-GALACTOSAMINE BOUND | LECTIN, PORE-FORMING TOXIN, BETA-TREFOIL, R-TYPE LECTIN, TOXIN
1mq4:A (ASP132) to (LEU164) CRYSTAL STRUCTURE OF AURORA-A PROTEIN KINASE | PROTEIN KINASE STRUCTURE, TRANSFERASE
1y9q:A (ASN89) to (SER120) CRYSTAL STRUCTURE OF HTH_3 FAMILY TRANSCRIPTIONAL REGULATOR FROM VIBRIO CHOLERAE | HTH_3 FAMILY, TRANSCRIPTIONAL REGULAATOR, STRUCUTRAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, DIMER, TWO-DOMAIN STRUCTURE, STRUCTURAL GENOMICS, TRANSCRIPTION REGULATOR
3a8d:A (GLN33) to (SER55) CRYSTAL STRUCTURE OF TRYPSIN COMPLEXED WITH (E)-2-(4- CARBAMIMIDOYLBENZYLIDENEAMINOOXY)ACETIC ACID (UNDER ANILINE-FREE CONDITION) | IN-CRYSTAL CHEMICAL LIGATION, DISULFIDE BOND, HYDROLASE, METAL- BINDING, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN
3kwf:A (PRO264) to (THR307) HUMAN DPP-IV WITH CARMEGLIPTIN (S)-1-((2S,3S,11BS)-2-AMINO- 9,10-DIMETHOXY-1,3,4,6,7,11B-HEXAHYDRO-2H-PYRIDO[2,1- A]ISOQUINOLIN-3-YL)-4-FLUOROMETHYL-PYRROLIDIN-2-ONE | DIABETES TYPE II, AMINOPEPTIDASE, CELL MEMBRANE, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, SERINE PROTEASE, SIGNAL-ANCHOR, TRANSMEMBRANE
1ymh:B (GLN3) to (ALA40) ANTI-HCV FAB 19D9D6 COMPLEXED WITH PROTEIN L (PPL) MUTANT A66W | ENGINEERING OF CRYSTAL CONTACTS, PPL-FAB COMPLEX, IMMUNE SYSTEM
3l3t:A (GLN30) to (SER54) HUMAN MESOTRYPSIN COMPLEXED WITH AMYLOID PRECURSOR PROTEIN INHIBITOR VARIANT (APPIR15K) | HUMAN MESOTRYPSIN, CANONICAL INHIBITOR, ALZHEIMER'S AMYLOID PRECURSOR PROTEIN INHIBITOR,APPI, APPI-R15K, HYDROLASE-CELL ADHESION COMPLEX
3l5f:B (MET79) to (GLY102) STRUCTURE OF BACE BOUND TO SCH736201 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
1yze:B (LEU95) to (HIS133) CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF USP7/HAUSP. | DEUBIQUITINATING ENZYME, APO FORM, TRAF DOMAIN, HYDROLASE
4pqx:A (THR40) to (ASN65) CRYSTAL STRUCTURE OF A NIGD-LIKE PROTEIN (BACCAC_02139) FROM BACTEROIDES CACCAE ATCC 43185 AT 2.39 A RESOLUTION | NIGD-LIKE PROTEIN, PF12667 FAMILY, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
4pqx:B (THR40) to (ASN65) CRYSTAL STRUCTURE OF A NIGD-LIKE PROTEIN (BACCAC_02139) FROM BACTEROIDES CACCAE ATCC 43185 AT 2.39 A RESOLUTION | NIGD-LIKE PROTEIN, PF12667 FAMILY, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
4pqx:C (SER39) to (ASN65) CRYSTAL STRUCTURE OF A NIGD-LIKE PROTEIN (BACCAC_02139) FROM BACTEROIDES CACCAE ATCC 43185 AT 2.39 A RESOLUTION | NIGD-LIKE PROTEIN, PF12667 FAMILY, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
4psr:A (ARG406) to (VAL431) CRYSTAL STRUCTURE OF ALPHA-L-FUCOSIDASE FROM FUSARIUM GRAMINEARUM IN THE OPEN FORM IN COMPLEX WITH L-FUCOSE | FUCOSIDASE, GH29, GLYCOSIDE HYDROLASE, TIM BARREL, N-GLYCOSYLATION, HYDROLASE
4psr:B (ARG406) to (VAL431) CRYSTAL STRUCTURE OF ALPHA-L-FUCOSIDASE FROM FUSARIUM GRAMINEARUM IN THE OPEN FORM IN COMPLEX WITH L-FUCOSE | FUCOSIDASE, GH29, GLYCOSIDE HYDROLASE, TIM BARREL, N-GLYCOSYLATION, HYDROLASE
3ak5:D (HIS507) to (ASP531) HEMOGLOBIN PROTEASE (HBP) PASSENGER MISSING DOMAIN-2 | AUTOTRANSPORTER, BETA HELIX, MUTANT, HYDROLASE
1zbw:A (THR286) to (GLN310) CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN SIGNALLING PROTEIN FROM GOAT MAMMARY GLAND (SPG-40) AND A TRIPEPTIDE TRP-PRO-TRP AT 2.8A RESOLUTION | SIGNALLING PROTEIN, LIGAND, WPW, 2.8A
4ap5:A (LEU166) to (LEU188) CRYSTAL STRUCTURE OF HUMAN POFUT2 | TRANSFERASE, GT-B, GT68
4ap5:B (LEU166) to (LEU188) CRYSTAL STRUCTURE OF HUMAN POFUT2 | TRANSFERASE, GT-B, GT68
4pwq:A (PRO32) to (ASP55) HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE E1-DOMAIN OF THE AMYLOID PRECURSOR PROTEIN | HEPARIN BINDING, DIMERIZATION, HEPARIN BINDING PROTEIN
1zlr:A (GLN30) to (THR54) FACTOR XI CATALYTIC DOMAIN COMPLEXED WITH 2-GUANIDINO-1-(4-(4,4,5,5- TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL)ETHYL NICOTINATE | SERINE PROTEASE, BORON, COVALENT INHIBITOR, HYDROLASE
1zmj:A (GLN30) to (THR54) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF FACTOR XI IN COMPLEX WITH 4-(GUANIDINOMETHYL)-PHENYLBORONIC ACID | FXI, INHIBITOR, HYDROLASE
3lpi:A (MET79) to (GLY102) STRUCTURE OF BACE BOUND TO SCH745132 | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE
3lqc:A (HIS56) to (LEU88) X-RAY CRYSTAL STRUCTURE OF OXIDIZED XRCC1 BOUND TO DNA POL BETA PALM THUMB DOMAIN | ALLOSTERIC DISULFIDE, SCAFFOLDING PROTEIN, DNA REPAIR, DNA DAMAGE, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, DNA REPLICATION, DNA SYNTHESIS, DNA-BINDING, DNA-DIRECTED DNA POLYMERASE, LYASE, MAGNESIUM, METAL-BINDING, NUCLEOTIDYLTRANSFERASE, SODIUM, TRANSFERASE, DNA-BINDING PROTEIN
4q5k:A (ILE198) to (HIS227) CRYSTAL STRUCTURE OF A N-ACETYLMURAMOYL-L-ALANINE AMIDASE (BACUNI_02947) FROM BACTEROIDES UNIFORMIS ATCC 8492 AT 1.30 A RESOLUTION | PF07313 FAMILY PROTEIN, DUF 1460, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
4ay0:B (ASN140) to (GLY163) HIGH RESOLUTION CRYSTAL STRUCTURE OF THE MONOMERIC SUBUNIT-FREE CAF1M CHAPERONE | CHAPERONE, AMINO ACID MOTIFS, BACTERIAL CAPSULES, BACTERIAL PROTEINS, GENE EXPRESSION REGULATION, MOLECULAR CHAPERONES, PROTEIN BINDING, PROTEIN CONFORMATION
5e5j:A (VAL11) to (GLU34) JOINT X-RAY/NEUTRON STRUCTURE OF HIV-1 PROTEASE TRIPLE MUTANT (V32I, I47V,V82I) WITH DARUNAVIR AT PH 6.0 | PROTEASE HIV-1 DRUG RESISTANT MUTANT INHIBITOR COMPLEX, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
5e6y:D (THR696) to (ALA727) CRYSTAL STRUCTURE OF E.COLI BRANCHING ENZYME IN COMPLEX WITH ALPHA CYCLODEXTRIN | BRANCHING ENZYME, CYCLODEXTRIN, GLYCOGEN, STARCH, GLUCAN, TRANSFERASE
5e7r:A (GLU35) to (ILE65) CRYSTAL STRUCTURE OF TL10-81 BOUND TO TAK1-TAB1 | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7/TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3lyy:A (ALA3) to (THR52) CRYSTAL STRUCTURE OF THE MUCBP DOMAIN OF THE ADHESION PROTEIN PEPE_0118 FROM PEDIOCOCCUS PENTOSACEUS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ID PTR41A | STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, CELL WALL, PEPTIDOGLYCAN-ANCHOR, CELL ADHESION
4q9s:A (ARG421) to (CYS456) CRYSTAL STRUCTURE OF HUMAN FOCAL ADHESION KINASE (FAK) BOUND TO COMPOUND1 (3,5-DIHYDRO[1,2,4]TRIAZINO[3,4-C][1,4]BENZOXAZIN-2(1H)- ONE) | KINASE CATALYTIC DOMAIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3m1u:A (LEU236) to (ILE259) CRYSTAL STRUCTURE OF A PUTATIVE GAMMA-D-GLUTAMYL-L-DIAMINO ACID ENDOPEPTIDASE (DVU_0896) FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH AT 1.75 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LIPOPROTEIN, HYDROLASE, SPORULATION
3m1u:B (LEU236) to (ILE259) CRYSTAL STRUCTURE OF A PUTATIVE GAMMA-D-GLUTAMYL-L-DIAMINO ACID ENDOPEPTIDASE (DVU_0896) FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH AT 1.75 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LIPOPROTEIN, HYDROLASE, SPORULATION
3m1u:B (MSE384) to (HIS408) CRYSTAL STRUCTURE OF A PUTATIVE GAMMA-D-GLUTAMYL-L-DIAMINO ACID ENDOPEPTIDASE (DVU_0896) FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH AT 1.75 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LIPOPROTEIN, HYDROLASE, SPORULATION
3azp:A (LEU318) to (ALA340) CRYSTAL STRUCTURE OF PUROMYCIN HYDROLASE S511A MUTANT | POP FAMILY, HYDROLASE
5edk:A (PHE507) to (THR539) CRYSTAL STRUCTURE OF PROTHROMBIN DELETION MUTANT RESIDUES 146-167 ( FORM II ). | PROTHROMBIN, KRINGLE, PROTEASE, COAGULATION FACTOR, ENZYME MECHANISM, KINETICS, STRUCTURE-FUNCTION, HYDROLASE
5eg7:A (TRP445) to (LYS478) THE CAP BINDING SITE OF INFLUENZA VIRUS PROTEIN PB2 AS A DRUG TARGET | PB2 CAP, VIRAL PROTEIN
4qlh:A (PRO1009) to (GLU1034) CRYSTAL STRUCTURE OF DRUG RESISTANT V82S/V1082S HIV-1 PROTEASE | TETHERED HIV-1 PROTEASE DIMER, PEPTIDE BOND HYDROLYSIS, HYDROLASE
3mew:A (ARG246) to (ALA280) CRYSTAL STRUCTURE OF NOVEL TUDOR DOMAIN-CONTAINING PROTEIN SGF29 | STRUCTURAL GENOMICS CONSORTIUM, SGC, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, CHROMOSOMAL PROTEIN, DNA-BINDING, NUCLEOSOME CORE
3b8j:A (GLN103) to (ASN133) Q191A MUTANT OF DEGS-DELTAPDZ | DEGS, PROTEASE, PERIPLASMIC STRESS SENSOR, HTRA, ALLOSTERIC ACTIVATION, HYDROLASE, SERINE PROTEASE
4beq:A (SER287) to (ARG307) STRUCTURE OF VIBRIO CHOLERAE BROAD SPECTRUM RACEMASE DOUBLE MUTANT R173A, N174A | ISOMERASE
5epy:A (ASP1103) to (LEU1127) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE A156T VARIANT IN COMPLEX WITH 5172-MCP1P3 (MK-5172 P1-P3 MACROCYCLIC ANALOGUE) | GRAZOPREVIR ANALOGUE, MACROCYCLE, DRUG RESISTANCE, HCV PROTEASE INHIBITOR, MK-5172, HYDROLASE
3mlq:E (VAL332) to (PRO364) CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS TRANSCRIPTION-REPAIR COUPLING FACTOR RNA POLYMERASE INTERACTING DOMAIN WITH THE THERMUS AQUATICUS RNA POLYMERASE BETA1 DOMAIN | TUDOR, TRANSFERASE-TRANSCRIPTION COMPLEX
3my2:A (LEU161) to (SER181) CRYSTAL STRUCTURE OF LPTC | LPTC, LIPOPOLYSACCHARIDE EXPORT PATHWAY, STRUCTURAL GENOMICS, SCOTTISH STRUCTURAL PROTEOMICS FACILITY, SSPF, TRANSPORT PROTEIN
4bti:B (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH THE DUAL THROMBIN-FXA INHIBITOR 58. | HYDROLASE, SAR107375, FACTOR XA INHIBITOR, THROMBIN INHIBITOR, CHLOROTHIOPHENE P1 FRAGMENT, S3 SUBSITE, MICROSOMES STABILITY, ORAL ANTITHROMBOTIC, DUAL INHIBITOR, IV ANTITHROMBOTIC
4bti:F (GLN30) to (THR54) FACTOR XA IN COMPLEX WITH THE DUAL THROMBIN-FXA INHIBITOR 58. | HYDROLASE, SAR107375, FACTOR XA INHIBITOR, THROMBIN INHIBITOR, CHLOROTHIOPHENE P1 FRAGMENT, S3 SUBSITE, MICROSOMES STABILITY, ORAL ANTITHROMBOTIC, DUAL INHIBITOR, IV ANTITHROMBOTIC
4bx9:A (ILE253) to (ASN290) HUMAN VPS33A IN COMPLEX WITH A FRAGMENT OF HUMAN VPS16 | PROTEIN TRANSPORT, HOPS, MEMBRANE TRAFFICKING, SEC1/MUNC18 PROTEINS, TETHERING
3nby:B (GLY126) to (PHE151) CRYSTAL STRUCTURE OF THE PKI NES-CRM1-RANGTP NUCLEAR EXPORT COMPLEX | PROTEIN TRANSPORT, GTP-BINDING PROTEIN-TRANSPORT PROTEIN COMPLEX
3ncl:A (GLN25) to (SER49) CRYSTAL STRUCTURE OF MT-SP1 BOUND TO BENZAMIDINE PHOSPHONATE INHIBITOR | PROTEINASE-INHIBITOR COMPLEX, SERINE PROTEINASE, BENZAMIDINE, PHOSPHONATE, SERINE ENDOPEPTIDASES, HYDROLASE
4rew:A (HIS17) to (ASN50) CRYSTAL STRUCTURE OF THE NON-PHOSPHORYLATED HUMAN ALPHA1 BETA2 GAMMA1 HOLO-AMPK COMPLEX | HUMAN ALPHA1 BETA2 GAMMA1 HOLO-AMPK COMPLEX, SERINE/THREONINE PROTEIN KINASE, AXIN, CAMKKBETA, LKB1, GLYCOGEN, PHOSPHORYLATION, TRANSFERASE
3cng:A (LYS38) to (LEU67) CRYSTAL STRUCTURE OF NUDIX HYDROLASE FROM NITROSOMONAS EUROPAEA | STRUCTURAL GENOMICS, APC7497, NUDIX HYDROLASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, HYDROLASE
3d23:B (VAL18) to (PRO39) MAIN PROTEASE OF HCOV-HKU1 | MAIN PROTEASE, ATP-BINDING, ENDONUCLEASE, EXONUCLEASE, HELICASE, MEMBRANE, METAL-BINDING, NUCLEASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, PROTEASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, THIOL PROTEASE, TRANSFERASE, TRANSMEMBRANE, ZINC-FINGER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4cre:A (GLN30) to (THR54) CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD GENERATION AND STRUCTURE AIDED DRUG DESIGN | HYDROLASE
4tlp:A (VAL119) to (ASP148) CRYSTAL STRUCTURE OF A ALANINE91 MUTANT OF WCI | HYDROLASE, INHIBITOR, CHYMOTRYPSIN INHIBITOR, TRYPTOPHAN
3oct:A (ASP401) to (ILE432) CRYSTAL STRUCTURE OF BRUTON'S TYROSINE KINASE MUTANT V555R IN COMPLEX WITH DASATINIB | TYROSINE KINASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ddp:C (ASN3) to (ASP38) STRUCTURE OF PHOSPHORYLATED THR160 CDK2/CYCLIN A IN COMPLEX WITH THE INHIBITOR CR8 | SER/THR PROTEIN KINASE; PHOSPHORYLATION; CELL CYCLE, ATP- BINDING, CELL DIVISION, MITOSIS, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, CYCLIN, CYTOPLASM, NUCLEUS, TRANSFERASE/CELL CYCLE COMPLEX
5gjq:Z (ARG828) to (HIS876) STRUCTURE OF THE HUMAN 26S PROTEASOME BOUND TO USP14-UBAL | PROTEIN COMPLEX, HUMAN PROTEASOME, HYDROLASE
3onu:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 | VIRAL CAPSID DOMAIN, VIRAL PROTEIN
3onu:B (GLY332) to (TRP381) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 | VIRAL CAPSID DOMAIN, VIRAL PROTEIN
3onu:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 | VIRAL CAPSID DOMAIN, VIRAL PROTEIN
4d9q:A (MET30) to (SER54) INHIBITING ALTERNATIVE PATHWAY COMPLEMENT ACTIVATION BY TARGETING THE EXOSITE ON FACTOR D | FACTOR D, COMPLEMENT, ANTIBODY, EXOSITE, FAB, CHYMOTRYPSIN, PROTEASE, HYDROLASE-IMMUNE SYSTEM COMPLEX
4d9q:B (MET30) to (SER54) INHIBITING ALTERNATIVE PATHWAY COMPLEMENT ACTIVATION BY TARGETING THE EXOSITE ON FACTOR D | FACTOR D, COMPLEMENT, ANTIBODY, EXOSITE, FAB, CHYMOTRYPSIN, PROTEASE, HYDROLASE-IMMUNE SYSTEM COMPLEX
5h9o:A (ASP766) to (TYR790) COMPLEX OF MURINE ENDOPLASMIC RETICULUM ALPHA-GLUCOSIDASE II WITH D- GLUCOSE | ENZYME GLYCOSYL HYDROLASE GH31 QUALITY CONTROL EXOGLYCOSIDASE, HYDROLASE
5h9o:C (ASP766) to (TYR790) COMPLEX OF MURINE ENDOPLASMIC RETICULUM ALPHA-GLUCOSIDASE II WITH D- GLUCOSE | ENZYME GLYCOSYL HYDROLASE GH31 QUALITY CONTROL EXOGLYCOSIDASE, HYDROLASE
3ou3:A (GLY40) to (GLY78) MDR769 HIV-1 PROTEASE COMPLEXED WITH PR/RT HEPTA-PEPTIDE | MDR HIV-1 PROTEASE, INHIBITOR, DRUG RESISTANCE, SUBSTRATE ENVELOPE, HIV-1 PROTEASE, PROTEASE, PR/RT SUBSTRATE PEPTIDE, NONE, HYDROLASE, HYDROLASE-PEPTIDE COMPLEX
4u42:B (ILE24) to (ASP57) MAP4K4 T181E MUTANT BOUND TO INHIBITOR COMPOUND 1 | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5heb:A (PHE325) to (SER361) THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT | PDZ, GLGF, DHR, ADHESION, SYNAPSE, SYNAPTIC DENSITY, PEPTIDE-BINDING DOMAIN, PEPTIDE BINDING PROTEIN
3oyi:A (GLN27) to (PRO50) CRYSTAL STRUCTURE OF THE PFV S217Q MUTANT INTASOME IN COMPLEX WITH MANGANESE | PROTEIN-DNA COMPLEX, TETRAMER, DNA INTEGRATION, ENDONUCLEASE, METAL- BINDING, MULTIFUNCTIONAL ENZYME, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, DNA-BINDING, ZINC BINDING, HHCC MOTIF, VIRAL PROTEIN, RECOMBINATION, INHIBITOR, DNA- BINDING PROTEIN-DNA COMPLEX, RECOMBINATION,VIRAL PROTEIN-DNA COMPLEX
3p95:A (GLN30) to (SER54) HUMAN MESOTRYPSIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR VARIANT (BPTI-K15R/R17D) | HUMAN MESOTRYPSIN-CANONICAL INHIBITOR COMPLEX, MESOTRYPSIN, TRYPSIN IV, BOVINE PANCREATIC TRYPSIN INHIBITOR, CANONICAL INHIBITOR, BPTI- K15R/R17D, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3pa2:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH HBGA TYPE LEY | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
3pa2:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH HBGA TYPE LEY | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
4ueh:H (GLN30) to (THR54) THROMBIN IN COMPLEX WITH BENZAMIDINE | HYDROLASE, HYDROLASE INHIBITOR COMPLEX, SERINE PROTEASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, BLOOD CLOTTING INHIBITOR, THROMBIN INHIBITOR, FRAGMENT, GLYCOSYLATION, BLOOD
5id8:C (ILE30) to (PRO54) CRYSTAL STRUCTURE OF CGL1 FROM CRASSOSTREA GIGAS, LIGAND FREE FORM (CGL1/FREE) | CGL1, LECTIN, N-TYPE, CRASSOSTREA GIGAS, UNKNOWN FUNCTION, SUGAR BINDING PROTEIN
5ief:A (ASP766) to (TYR790) MURINE ENDOPLASMIC RETICULUM ALPHA-GLUCOSIDASE II WITH N-BUTYL-1- DEOXYNOJIRIMYCIN | ENZYME GLYCOSYL HYDROLASE GH31 QUALITY CONTROL EXOGLYCOSIDASE, HYDROLASE, NB-DNJ
3pvd:A (GLU468) to (ALA497) CRYSTAL STRUCTURE OF P DOMAIN DIMER OF NOROVIRUS VA207 COMPLEXED WITH 3'-SIALYL-LEWIS X TETRASACCHARIDE | GREEK KEY, MIXED ALPHA/BETA STRUCTURE, RECEPTOR BINDING, CARBOHYDRATE/SUGAR BINDING, CAPSID, VIRAL PROTEIN
3pvd:B (GLU468) to (ALA497) CRYSTAL STRUCTURE OF P DOMAIN DIMER OF NOROVIRUS VA207 COMPLEXED WITH 3'-SIALYL-LEWIS X TETRASACCHARIDE | GREEK KEY, MIXED ALPHA/BETA STRUCTURE, RECEPTOR BINDING, CARBOHYDRATE/SUGAR BINDING, CAPSID, VIRAL PROTEIN
3q00:A (GLN30) to (SER54) BOVINE TRYPSIN VARIANT X(TRIPLEGLU217ILE227) IN COMPLEX WITH SMALL MOLECULE INHIBITOR | TRYPSIN-LIKE SERINE PROTEASE, HYDROLASE, PROTEIN BINDING, DUODENUM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4en8:B (ASN401) to (GLU430) CRYSTAL STRUCTURE OF HA70 (HA3) SUBCOMPONENT OF CLOSTRIDIUM BOTULINUM TYPE C PROGENITOR TOXIN IN COMPLEX WITH ALPHA 2-6-SIALYLLACTOSE | CARBOHYDRATE/SUGAR BINDING, SUGAR BINDING PROTEIN
3q38:A (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH HBGA TYPE B (TRIGLYCAN) | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
3q38:B (ASP479) to (ALA508) CRYSTAL STRUCTURE OF P DOMAIN FROM NORWALK VIRUS STRAIN VIETNAM 026 IN COMPLEX WITH HBGA TYPE B (TRIGLYCAN) | NOROVIRUS, P-DOMAIN, CAPSID, RECEPTOR, HISTO BLOOD GROUP ANTIGEN (HBGA), VIRAL PROTEIN
3q48:B (LEU159) to (ALA188) CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA CUPB2 CHAPERONE | IG FOLD, PERIPLASMIC CHAPERONE, CUPB1, CHAPERONE
4es5:A (TRP449) to (LYS482) CRYSTAL STRUCTURE OF THE CAP-BINDING DOMAIN OF POLYMERASE BASIC PROTEIN 2 FROM INFLUENZA VIRUS A/BAR-HEADED GS/QINGHAI/15C/2005 (H5N1) WITH BOUND M7GTP | CAP-BINDING PROTEIN, TRANSCRIPTION
4es5:B (TRP449) to (LYS482) CRYSTAL STRUCTURE OF THE CAP-BINDING DOMAIN OF POLYMERASE BASIC PROTEIN 2 FROM INFLUENZA VIRUS A/BAR-HEADED GS/QINGHAI/15C/2005 (H5N1) WITH BOUND M7GTP | CAP-BINDING PROTEIN, TRANSCRIPTION
4es5:C (TRP449) to (LYS482) CRYSTAL STRUCTURE OF THE CAP-BINDING DOMAIN OF POLYMERASE BASIC PROTEIN 2 FROM INFLUENZA VIRUS A/BAR-HEADED GS/QINGHAI/15C/2005 (H5N1) WITH BOUND M7GTP | CAP-BINDING PROTEIN, TRANSCRIPTION
4es5:D (TRP449) to (SER481) CRYSTAL STRUCTURE OF THE CAP-BINDING DOMAIN OF POLYMERASE BASIC PROTEIN 2 FROM INFLUENZA VIRUS A/BAR-HEADED GS/QINGHAI/15C/2005 (H5N1) WITH BOUND M7GTP | CAP-BINDING PROTEIN, TRANSCRIPTION
5iw7:A (PRO734) to (ASP760) CRYSTAL STRUCTURE OF YEAST TSR1, A PRE-40S RIBOSOME SYNTHESIS FACTOR | TRANSLATIONAL GTPASE RIBOSOME SYNTHESIS, TRANSLATION
5ixl:A (GLY62) to (ILE85) STRUCTURE OF P. VULGARIS HIGB TOXIN Y91A VARIANT | BACTERIAL TOXINS, BIOFILMS, CELL METABOLISM, ENERGY METABOLISM, MICROBIAL PATHOGENESIS, STRESS RESPONSE, STRINGENT RESPONSE, TRANSLATION CONTROL, HYDROLASE
5ixl:D (GLY62) to (ILE85) STRUCTURE OF P. VULGARIS HIGB TOXIN Y91A VARIANT | BACTERIAL TOXINS, BIOFILMS, CELL METABOLISM, ENERGY METABOLISM, MICROBIAL PATHOGENESIS, STRESS RESPONSE, STRINGENT RESPONSE, TRANSLATION CONTROL, HYDROLASE
5iya:U (ASN270) to (TRP298) HUMAN CORE-PIC IN THE CLOSED STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
3qdz:D (GLN30) to (THR54) CRYSTAL STRUCTURE OF THE HUMAN THROMBIN MUTANT D102N IN COMPLEX WITH THE EXTRACELLULAR FRAGMENT OF HUMAN PAR4. | SERINE PROTEASE, PROTEIN FUNCTION, PROTEASE-ACTIVATED RECEPTORS, HYDROLASE-HYDROLASE RECEPTOR COMPLEX
4f1m:A (GLU1025) to (ASP1061) CRYSTAL STRUCTURE OF THE G1179S ROCO4 KINASE DOMAIN BOUND TO APPCP FROM D. DISCOIDEUM. | PROTEIN KINASE, LRRK2, ROCO, KINASE, ATP-BINDING, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, SIGNALING PROTEIN
3qx5:H (GLN30) to (THR54) THROMBIN INHIBITION BY PYRIDIN DERIVATIVES | SERINE PROTEASE, KRINGLE, HYDROLASE, BLOOD COAGULATION, BLOOD CLOTTING, CONVERTION OF FIBRINOGEN TO FIBRIN, CLEAVAGE ON PAIRS OF BASIC RESIDUES, BLOOD CLOTTING INHIBITOR, THROMBIN INHIBITOR, GLYCOSYLATION, BLOOD, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3r4d:C (PRO113) to (PHE145) CRYSTAL STRUCTURE OF MOUSE CORONAVIRUS RECEPTOR-BINDING DOMAIN COMPLEXED WITH ITS MURINE RECEPTOR | IMMUNOGLOBULIN, BETA-SANDWICH, MCEACAM1A - IMMUNOGLOBULIN FOLD MHV SPIKE NTD - GALECTIN-LIKE BETA-SANDWICH FOLD, MCEACAM1A - CELL ADHESION MHV SPIKE NTD - MCEACAM1A BINDING, MCEACAM1A - ITSELF AND MHV SPIKE NTD MHV SPIKE NTD - MCEACAM1A, N-GLYCOSYLATIONS, MCEACAM1A - 37, 55, 70 MHV SPIKE NTD - 192, CELL ADHESION-VIRAL PROTEIN COMPLEX
4w8t:A (PHE71) to (SER115) CRYSTAL STRUCTURE OF TRUNCATED HEMOLYSIN A Q125S FROM P. MIRABILIS AT 1.5 ANGSTROMS RESOLUTION | HEMOLYSIN, TWO PARTNER SECRETION, BETA SOLENOID, BETA HELIX, TOXIN
5jb9:S (GLN30) to (THR54) CRYSTAL STRUCTURE OF FACTOR IXA K98T VARIANT IN COMPLEX WITH PPACK | BLOOD CLOTTING, HYDROLASE, GLYCOPROTEIN, HAEMOSTASIS
5jkn:A (SER312) to (LEU333) CRYSTAL STRUCTURE OF DEUBIQUITINASE MINDY-1 | HYDROLASE, CYSTEINE PROTEASE, ISOPEPTIDASE AND UBIQUITIN BINDING
4fse:A (MET66) to (GLY89) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH N-(N-(4-AMINO-3,5- DICHLOROBENZYL)CARBAMIMIDOYL)-3-(4- METHOXYPHENYL)-5- METHYL-4-ISOTHIAZOLECARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2, BASE, ASPARTIC PROTEASE, HYDROLASE-INHIBITOR COMPLEX
5jod:A (LEU14) to (PRO43) STRUCTURE OF PROPLASMEPSIN IV FROM PLASMODIUM FALCIPARUM | MALARIA, HYDROLASE
5jqp:A (ASP759) to (TRP784) CRYSTAL STRUCTURE OF ER GLUCOSIDASE II HETERODIMERIC COMPLEX CONSISTING OF CATALYTIC SUBUNIT AND THE BINDING DOMAIN OF REGULATORY SUBUNIT | PROTEIN TRANSPORT, HYDROLASE
5k3y:B (ASP92) to (PHE125) CRYSTAL STRUCTURE OF AURORAB/INCENP IN COMPLEX WITH BI 811283 | KINASE, INHIBITOR, TRANSFERASE
5kod:A (PHE345) to (PRO373) CRYSTAL STRUCTURE OF GH3.5 ACYL ACID AMIDO SYNTHETASE FROM ARABIDOPSIS THALIANA | ANL, ADENYLATING ENZYME, ACYL ACID AMIDO SYNTHETASE, ADENYLATION LIGASE, LIGASE
5kod:C (PHE345) to (PRO373) CRYSTAL STRUCTURE OF GH3.5 ACYL ACID AMIDO SYNTHETASE FROM ARABIDOPSIS THALIANA | ANL, ADENYLATING ENZYME, ACYL ACID AMIDO SYNTHETASE, ADENYLATION LIGASE, LIGASE
5kod:D (TYR368) to (GLY426) CRYSTAL STRUCTURE OF GH3.5 ACYL ACID AMIDO SYNTHETASE FROM ARABIDOPSIS THALIANA | ANL, ADENYLATING ENZYME, ACYL ACID AMIDO SYNTHETASE, ADENYLATION LIGASE, LIGASE
5l1e:A (TYR356) to (GLU384) AMPA SUBTYPE IONOTROPIC GLUTAMATE RECEPTOR GLUA2 IN COMPLEX WITH NONCOMPETITIVE INHIBITOR CP465022 | TRANSPORTER, MEMBRANE PROTEIN, TRANSPORT PROTEIN, TRANSPORT PROTEIN- INHIBITOR COMPLEX
5l1f:C (ASN355) to (GLU384) AMPA SUBTYPE IONOTROPIC GLUTAMATE RECEPTOR GLUA2 IN COMPLEX WITH NONCOMPETITIVE INHIBITOR PERAMPANEL | TRANSPORTER, MEMBRANE PROTEIN, TRANSPORT PROTEIN, TRANSPORT PROTEIN- INHIBITOR COMPLEX
5l4k:U (VAL120) to (THR159) THE HUMAN 26S PROTEASOME LID | PROTEOSTASIS, AAA-ATPASE, STRUCTURAL PROTEIN
5sx3:A (TYR348) to (LEU386) CRYSTAL STRUCTURE OF THE CATALASE-PEROXIDASE KATG OF B. PSEUDOMAALLEI AT PH 4.5 | CATALASE-PEROXIDASE, KATG, PH CHANGES, OXIDOREDUCTASE
5t3h:A (GLN30) to (SER54) BOVINE TRYPSIN SOAKED WITH SELENOUREA FOR 5 MIN | TRYPSIN, SELENOUREA, HYDROLASE
7lpr:A (ILE29) to (ALA55) STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX