2o8m:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF THE S139A MUTANT OF HEPATITIS C VIRUS NS3/4A PROTEASE | SERINE PROTEASE, NS3, NS4A, HEPATITIS C VIRUS, VIRAL PROTEIN
2o8m:B (GLY140) to (ILE170) CRYSTAL STRUCTURE OF THE S139A MUTANT OF HEPATITIS C VIRUS NS3/4A PROTEASE | SERINE PROTEASE, NS3, NS4A, HEPATITIS C VIRUS, VIRAL PROTEIN
1a0l:B (GLY197) to (THR229) HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE | TRYPSIN-LIKE SERINE PROTEINASE, TETRAMER, HEPARIN, ALLERGY, ASTHMA, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1a0l:C (GLY197) to (THR229) HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE | TRYPSIN-LIKE SERINE PROTEINASE, TETRAMER, HEPARIN, ALLERGY, ASTHMA, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1a1r:A (GLY166) to (ILE196) HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX | VIRAL PROTEIN, SERINE PROTEASE, NONSTRUCTURAL PROTEINS, COFACTOR PEPTIDE, HELICASE
1a1r:B (GLY166) to (ILE196) HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX | VIRAL PROTEIN, SERINE PROTEASE, NONSTRUCTURAL PROTEINS, COFACTOR PEPTIDE, HELICASE
2obo:A (GLY140) to (ILE170) STRUCTURE OF HEPATITIS C VIRAL NS3 PROTEASE DOMAIN COMPLEXED WITH NS4A PEPTIDE AND KETOAMIDE SCH476776 | KETOAMIDE INHIBITOR, VIRAL PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2obq:C (GLY140) to (ILE170) DISCOVERY OF THE HCV NS3/4A PROTEASE INHIBITOR SCH503034. KEY STEPS IN STRUCTURE-BASED OPTIMIZATION | HCV, HEPATITIS C VIRUS, NS3 PROTEASE,, VIRAL PROTEIN
2oc0:A (GLY140) to (ILE170) STRUCTURE OF NS3 COMPLEXED WITH A KETOAMIDE INHIBITOR SCH491762 | HEPATITIS C VIRUS, HCV, NS3 PROTEASE DOMAIN, KETOAMIDE INHIBITOR, VIRAL PROTEIN
2oc1:A (GLY140) to (ILE170) STRUCTURE OF THE HCV NS3/4A PROTEASE INHIBITOR CVS4819 | HEPATITIS C VIRUS, HCV, NS3 PROTEASE DOMAIN, KETOAMIDE INHIBITOR, VIRAL PROTEIN
2oc7:A (GLY140) to (ILE170) STRUCTURE OF HEPATITIS C VIRAL NS3 PROTEASE DOMAIN COMPLEXED WITH NS4A PEPTIDE AND KETOAMIDE SCH571696 | HEPATITIS C VIRUS, HCV, NS3 PROTEASE DOMAIN, KETOAMIDE INHIBITOR, VIRAL PROTEIN
2oc7:C (GLY140) to (ILE170) STRUCTURE OF HEPATITIS C VIRAL NS3 PROTEASE DOMAIN COMPLEXED WITH NS4A PEPTIDE AND KETOAMIDE SCH571696 | HEPATITIS C VIRUS, HCV, NS3 PROTEASE DOMAIN, KETOAMIDE INHIBITOR, VIRAL PROTEIN
2oc8:A (GLY140) to (ILE170) STRUCTURE OF HEPATITIS C VIRAL NS3 PROTEASE DOMAIN COMPLEXED WITH NS4A PEPTIDE AND KETOAMIDE SCH503034 | HEPATITIS C VIRUS, HCV, NS3 PROTEASE DOMAIN, KETOAMIDE INHIBITOR, VIRAL PROTEIN
2oc8:C (GLY140) to (ILE170) STRUCTURE OF HEPATITIS C VIRAL NS3 PROTEASE DOMAIN COMPLEXED WITH NS4A PEPTIDE AND KETOAMIDE SCH503034 | HEPATITIS C VIRUS, HCV, NS3 PROTEASE DOMAIN, KETOAMIDE INHIBITOR, VIRAL PROTEIN
3e8r:A (GLY349) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TACE WITH HYDROXAMATE INHIBITOR | TACE ADAM17 ZN-ENDOPEPTIDASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, GLYCOPROTEIN, HYDROLASE, MEMBRANE, METAL-BINDING, METALLOPROTEASE, NOTCH SIGNALING PATHWAY, PHOSPHOPROTEIN, PROTEASE, SH3-BINDING, TRANSMEMBRANE, ZYMOGEN
3e8r:B (LEU348) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TACE WITH HYDROXAMATE INHIBITOR | TACE ADAM17 ZN-ENDOPEPTIDASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, GLYCOPROTEIN, HYDROLASE, MEMBRANE, METAL-BINDING, METALLOPROTEASE, NOTCH SIGNALING PATHWAY, PHOSPHOPROTEIN, PROTEASE, SH3-BINDING, TRANSMEMBRANE, ZYMOGEN
1a5h:A (ASN179) to (GLY211) CATALYTIC DOMAIN OF HUMAN TWO-CHAIN TISSUE PLASMINOGEN ACTIVATOR COMPLEX OF A BIS-BENZAMIDINE | TRYPSIN LIKE SERINE PROTEASE, FIBRINOLYTIC ENZYME, HYDROLASE
1a5h:B (ASN179) to (GLY211) CATALYTIC DOMAIN OF HUMAN TWO-CHAIN TISSUE PLASMINOGEN ACTIVATOR COMPLEX OF A BIS-BENZAMIDINE | TRYPSIN LIKE SERINE PROTEASE, FIBRINOLYTIC ENZYME, HYDROLASE
1nc6:A (GLY197) to (THR229) POTENT, SMALL MOLECULE INHIBITORS OF HUMAN MAST CELL TRYPTASE. ANTI-ASTHMATIC ACTION OF A DIPEPTIDE-BASED TRANSITION STATE ANALOGUE CONTAINING BENZOTHIAZOLE KETONE | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
3eay:A (HIS794) to (PRO867) CRYSTAL STRUCTURE OF THE HUMAN SENP7 CATALYTIC DOMAIN | PROTEASE, SENTRIN-SPECIFIC PROTEASE, ULP, SENP, SUMO, UBIQUITIN, CRYSTAL, ALTERNATIVE SPLICING, HYDROLASE, PHOSPHOPROTEIN, POLYMORPHISM, THIOL PROTEASE, UBL CONJUGATION PATHWAY
2amp:A (ASN64) to (ASN91) CRYSTAL STRUCTURE OF PORCINE TRANSMISSIBLE GASTROENTERITIS VIRUS MPRO IN COMPLEX WITH AN INHIBITOR N1 | ANTI-PARALLEL B-BARREL, ANTI-PARALLEL A-HELICES, HYDROLASE
2ogj:B (ARG346) to (LYS372) CRYSTAL STRUCTURE OF A DIHYDROOROTASE | TIM BARREL, BINUCLEAR ZINC, IMIDAZOLE COMPLEX, AMIDO HYDROLASE, 9244B, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, HYDROLASE
2ogv:A (ASN773) to (ILE794) CRYSTAL STRUCTURE OF THE AUTOINHIBITED HUMAN C-FMS KINASE DOMAIN | RECEPTOR TYROSINE KINASE, MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR, TRANSFERASE
4wh6:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE VARIANT R155K IN COMPLEX WITH ASUNAPREVIR | HCV DRUG RESISTANT, PROTEASE-INHIBITOR COMPLEX, ASUNAPREVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2oi0:A (LEU348) to (LEU380) CRYSTAL STRUCTURE ANALYSIS 0F THE TNF-A COVERTING ENZYME (TACE) IN COMPLEXED WITH ARYL-SULFONAMIDE | TNF-A COVERTING ENZYME, ARYL-SULFONAMIDE, TACE INHIBITORS, HYDROLASE
2oin:A (GLY166) to (ILE196) CRYSTAL STRUCTURE OF HCV NS3-4A R155K MUNTANT | HCV, PROTEASE, NS3-4A, R155K MUTANT, HYDROLASE
2oin:B (GLY1166) to (ILE1196) CRYSTAL STRUCTURE OF HCV NS3-4A R155K MUNTANT | HCV, PROTEASE, NS3-4A, R155K MUTANT, HYDROLASE
3rqw:J (GLU159) to (PRO201) CRYSTAL STRUCTURE OF ACETYLCHOLINE BOUND TO A PROKARYOTIC PENTAMERIC LIGAND-GATED ION CHANNEL, ELIC | ION CHANNEL, MEMBRANE, TRANSPORT PROTEIN
1nhc:C (ASP251) to (ASN280) STRUCTURAL INSIGHTS INTO THE PROCESSIVITY OF ENDOPOLYGALACTURONASE I FROM ASPERGILLUS NIGER | BETA-HELIX, HYDROLASE
1nhc:D (ASP251) to (ASN280) STRUCTURAL INSIGHTS INTO THE PROCESSIVITY OF ENDOPOLYGALACTURONASE I FROM ASPERGILLUS NIGER | BETA-HELIX, HYDROLASE
1nhc:E (ASP251) to (ASN280) STRUCTURAL INSIGHTS INTO THE PROCESSIVITY OF ENDOPOLYGALACTURONASE I FROM ASPERGILLUS NIGER | BETA-HELIX, HYDROLASE
4wjg:C (LEU217) to (LYS247) STRUCTURE OF T. BRUCEI HAPTOGLOBIN-HEMOGLOBIN RECEPTOR BINDING TO HUMAN HAPTOGLOBIN-HEMOGLOBIN | ENDOCYTOSIS, TRYPANOSOME, RECEPTOR
4wjg:H (LEU217) to (LYS247) STRUCTURE OF T. BRUCEI HAPTOGLOBIN-HEMOGLOBIN RECEPTOR BINDING TO HUMAN HAPTOGLOBIN-HEMOGLOBIN | ENDOCYTOSIS, TRYPANOSOME, RECEPTOR
4wjg:M (LEU217) to (LYS247) STRUCTURE OF T. BRUCEI HAPTOGLOBIN-HEMOGLOBIN RECEPTOR BINDING TO HUMAN HAPTOGLOBIN-HEMOGLOBIN | ENDOCYTOSIS, TRYPANOSOME, RECEPTOR
4wjg:R (LEU217) to (LYS247) STRUCTURE OF T. BRUCEI HAPTOGLOBIN-HEMOGLOBIN RECEPTOR BINDING TO HUMAN HAPTOGLOBIN-HEMOGLOBIN | ENDOCYTOSIS, TRYPANOSOME, RECEPTOR
4wjg:W (LEU217) to (LYS247) STRUCTURE OF T. BRUCEI HAPTOGLOBIN-HEMOGLOBIN RECEPTOR BINDING TO HUMAN HAPTOGLOBIN-HEMOGLOBIN | ENDOCYTOSIS, TRYPANOSOME, RECEPTOR
4wjg:2 (LEU217) to (LYS247) STRUCTURE OF T. BRUCEI HAPTOGLOBIN-HEMOGLOBIN RECEPTOR BINDING TO HUMAN HAPTOGLOBIN-HEMOGLOBIN | ENDOCYTOSIS, TRYPANOSOME, RECEPTOR
3edz:B (GLY349) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TACE WITH HYDROXAMATE INHIBITOR | HYDROLASE, ZN-ENDOPEPTIDASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, GLYCOPROTEIN, MEMBRANE, METAL-BINDING, METALLOPROTEASE, NOTCH SIGNALING PATHWAY, PHOSPHOPROTEIN, PROTEASE, SH3-BINDING, TRANSMEMBRANE, ZYMOGEN
2olq:A (GLY227) to (GLY248) HOW DOES AN ENZYME RECOGNIZE CO2? | PHOSPHOENOLPYRUVATE CARBOXYKINASE, CO2, LYASE
2olr:A (GLY227) to (GLY248) CRYSTAL STRUCTURE OF ESCHERICHIA COLI PHOSPHOENOLPYRUVATE CARBOXYKINASE COMPLEXED WITH CARBON DIOXIDE, MG2+, ATP | CARBON DIOXIDE, CARBOXYKINASE, LYASE
1njj:A (VAL335) to (ARG369) CRYSTAL STRUCTURE DETERMINATION OF T. BRUCEI ORNITHINE DECARBOXYLASE BOUND TO D-ORNITHINE AND TO G418 | ORNITHINE DECARBOXYLASE, ODC, PLP, PYRIDOXAL 5'-PHOSPHATE, D-ORNITHINE, G418, LYASE
1njj:B (VAL335) to (ARG369) CRYSTAL STRUCTURE DETERMINATION OF T. BRUCEI ORNITHINE DECARBOXYLASE BOUND TO D-ORNITHINE AND TO G418 | ORNITHINE DECARBOXYLASE, ODC, PLP, PYRIDOXAL 5'-PHOSPHATE, D-ORNITHINE, G418, LYASE
1ai4:B (VAL118) to (ALA142) PENICILLIN ACYLASE COMPLEXED WITH 3,4-DIHYDROXYPHENYLACETIC ACID | ANTIBIOTIC RESISTANCE, LIGAND INDUCED CONFORMATIONAL CHANGE, HYDROLASE
4wme:D (SER65) to (THR93) CRYSTAL STRUCTURE OF CATALYTICALLY INACTIVE MERS-COV 3CL PROTEASE (C148A) IN SPACEGROUP C2 | MERS, CORONAVIRUS, 3CL PROTEASE, HYDROLASE
1ajq:B (VAL118) to (ALA142) PENICILLIN ACYLASE COMPLEXED WITH THIOPHENEACETIC ACID | ANTIBIOTIC RESISTANCE, LIGAND INDUCED CONFORMATIONAL CHANGE, HYDROLASE
1nn6:A (GLY198) to (THR225) HUMAN PRO-CHYMASE | SERINE PROTEASE, ZYMOGEN, CHYMASE, CONFORMATIONAL CHANGE, HYDROLASE
4h19:E (THR4) to (THR28) CRYSTAL STRUCTURE OF AN ENOLASE (MANDELATE RACEMASE SUBGROUP, TARGET EFI-502087) FROM AGROBACTERIUM TUMEFACIENS, WITH BOUND MG AND D- RIBONOHYDROXAMATE, ORDERED LOOP | ENOLASE, MANDELATE RACEMASE SUBGROUP, ENZYME FUNCTION INITIATIVE, EFI, STRUCTURAL GENOMICS, LYASE
4h1z:B (LYS7) to (PHE49) CRYSTAL STRUCTURE OF PUTATIVE ISOMERASE FROM SINORHIZOBIUM MELILOTI, OPEN LOOP CONFORMATION (TARGET EFI-502104) | DEHYDRATASE, MAGNESIUM BINDING SITE, ENZYME FUNCTION INITIATIVE, EFI, ISOMERASE
4h1z:F (LYS7) to (PHE49) CRYSTAL STRUCTURE OF PUTATIVE ISOMERASE FROM SINORHIZOBIUM MELILOTI, OPEN LOOP CONFORMATION (TARGET EFI-502104) | DEHYDRATASE, MAGNESIUM BINDING SITE, ENZYME FUNCTION INITIATIVE, EFI, ISOMERASE
4h1z:G (LYS7) to (PHE49) CRYSTAL STRUCTURE OF PUTATIVE ISOMERASE FROM SINORHIZOBIUM MELILOTI, OPEN LOOP CONFORMATION (TARGET EFI-502104) | DEHYDRATASE, MAGNESIUM BINDING SITE, ENZYME FUNCTION INITIATIVE, EFI, ISOMERASE
1nol:A (THR482) to (HIS503) OXYGENATED HEMOCYANIN (SUBUNIT TYPE II) | OXYGEN TRANSPORT
1npl:A (ILE72) to (THR99) MANNOSE-SPECIFIC AGGLUTININ (LECTIN) FROM DAFFODIL (NARCISSUS PSEUDONARCISSUS) BULBS IN COMPLEX WITH MANNOSE-ALPHA1,3-MANNOSE | LECTIN, AGGLUTININ, MANNOBIOSE, MANNOSE-ALPHA1, 3-MANNOSE, DAFFODIL, SUGAR BINDING PROTEIN
1aq2:A (GLY227) to (GLY248) PHOSPHOENOLPYRUVATE CARBOXYKINASE | KINASE, TRANSPHOSPHORYLATING, P-LOOP, PROTEIN-ATP COMPLEX, NUCLEOTIDE-TRIPHOSPHATE HYDROLASE, LYASE, GLUCONEOGENESIS
1arc:A (SER196) to (GLY228) THE PRIMARY STRUCTURE AND STRUCTURAL CHARACTERISTICS OF ACHROMOBACTER LYTICUS PROTEASE I, A LYSINE-SPECIFIC SERINE PROTEASE | SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ns3:A (GLY140) to (VAL170) STRUCTURE OF HCV PROTEASE (BK STRAIN) | HYDROLASE, SERINE PROTEINASE, COMPLEX (HYDROLASE-PEPTIDE), COMPLEX (HYDROLASE-PEPTIDE) COMPLEX
1ns3:B (GLY140) to (VAL170) STRUCTURE OF HCV PROTEASE (BK STRAIN) | HYDROLASE, SERINE PROTEINASE, COMPLEX (HYDROLASE-PEPTIDE), COMPLEX (HYDROLASE-PEPTIDE) COMPLEX
2b5r:C (GLY1141) to (ASP1163) 1B LACTAMASE / B LACTAMASE INHIBITOR | PROTEIN-PROTEIN COMPLEX, STRUCTURAL GENOMICS, ISRAEL STRUCTURAL PROTEOMICS CENTER, ISPC, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1ntg:D (VAL62) to (GLY80) CRYSTAL STRUCTURE OF THE EMAP II-LIKE CYTOKINE RELEASED FROM HUMAN TYROSYL-TRNA SYNTHETASE | BETA BARREL, LIGASE
3s15:B (GLY902) to (LEU941) RNA POLYMERASE II INITIATION COMPLEX WITH A 7-NT RNA | RNA POLYMERASE II, INITIATION COMPLEX, TRANSCRIPTION-RNA-DNA COMPLEX
3ent:A (PRO69) to (GLU84) CRYSTAL STRUCTURE OF NITROLLIN, A BETAGAMMA-CRYSTALLIN FROM NITROSOSPIRA MULTIFORMIS-IN ALTERNATE SPACE GROUP (P65) | BETAGAMMA CRYSTALLIN, STRUCTURAL PROTEIN
3ent:B (PRO69) to (GLU84) CRYSTAL STRUCTURE OF NITROLLIN, A BETAGAMMA-CRYSTALLIN FROM NITROSOSPIRA MULTIFORMIS-IN ALTERNATE SPACE GROUP (P65) | BETAGAMMA CRYSTALLIN, STRUCTURAL PROTEIN
3enu:A (ALA70) to (GLU84) CRYSTAL STRUCTURE OF NITROLLIN, A BETAGAMMA-CRYSTALLIN FROM NITROSOSPIRA MULTIFORMIS | BETAGAMMA CRYSTALLIN, STRUCTURAL PROTEIN
1nu9:D (ARG206) to (THR229) STAPHYLOCOAGULASE-PRETHROMBIN-2 COMPLEX | THROMBIN NON-PROTEOLYTIC ACTIVATOR, ENDOCARDITIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEIN BINDING
4h8w:G (GLY263) to (ASN289) CRYSTAL STRUCTURE OF NON-NEUTRALIZING AND ADCC-POTENT ANTIBODY N5-I5 IN COMPLEX WITH HIV-1 CLADE A/E GP120 AND SCD4. | HIV-1 GP120, CLADE A/E 93TH057, VIRAL PROTEIN, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
1ayl:A (GLY227) to (GLY248) PHOSPHOENOLPYRUVATE CARBOXYKINASE | P-LOOP, PROTEIN-ATP COMPLEX, NUCLEOTIDE-TRIPHOSPHATE HYDROLASE, KINASE (TRANSPHOSPHORYLATING)
2b8k:B (GLY902) to (LEU941) 12-SUBUNIT RNA POLYMERASE II | DNA-DIRECTED RNA POLYMERASE, DNA-DEPENDENT RNA POLYMERASE, CELLULAR RNA POLYMERASE, METAL-BINDING, NUCLEAR PROTEIN, TRANSCRIPTION, TRANSFERASE
4wt5:B (LYS342) to (ASP386) THE C-TERMINAL DOMAIN OF RUBISCO ACCUMULATION FACTOR 1 FROM ARABIDOPSIS THALIANA, CRYSTAL FORM II | ASSEMBLY CHAPERONE, CHAPERONE
2b8t:B (ASP144) to (CYS191) CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM U.UREALYTICUM IN COMPLEX WITH THYMIDINE | DEOXYRIBONUCLEOSIDE KINASE, ZINC-BINDING DOMAIN, TK1, UU-TK, THYMIDINE, TRANSFERASE
1b0f:A (SER197) to (ALA229) CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL ELASTASE WITH MDL 101, 146 | SERINE PROTEASE, FLUOROETHYL KETONES, HYDROLASE
2p1f:A (LEU224) to (SER245) HUMAN UMP SYNTHASE (C-TERMINAL DOMAIN-OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE) | UMP SYNTHASE, C-TERMINAL DOMAIN, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, HUMAN, HYDROLASE
1b1z:D (PRO29) to (GLU61) STREPTOCOCCAL PYROGENIC EXOTOXIN A1 | SUPERANTIGEN, ZINC BINDING, PYROGENIC EXOTOXIN
4wvp:E (SER197) to (ALA229) CRYSTAL STRUCTURE OF AN ACTIVITY-BASED PROBE HNE COMPLEX | NEUTROPHIL ELASTASE, ACITIVITY-BASED PROBE, INHIBITOR, PROTEASE, COMPLEX, HNE, HYCOSUL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2bd9:A (GLY197) to (THR229) PORCINE PANCREATIC ELASTASE COMPLEXED WITH BETA-CASOMORPHIN-7 AND ARG- PHE AT PH 5.0 (50 MIN SOAK) AND IMMERSED IN PH 9 BUFFER FOR 28 SECONDS (2ND PH JUMP) | SERINE PROTEINASE, HYDROLASE
2p59:A (GLY166) to (ILE196) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS3.4A PROTEASE | HCV PROTEASE, VIRAL PROTEIN
3est:A (GLY197) to (THR229) STRUCTURE OF NATIVE PORCINE PANCREATIC ELASTASE AT 1.65 ANGSTROMS RESOLUTION | HYDROLASE(SERINE PROTEINASE)
4wy1:A (THR59) to (GLU79) CRYSTAL STRUCTURE OF HUMAN BACE-1 BOUND TO COMPOUND 24B | BETA SECRETASE BACE PROTEASE
2p6w:A (ASP80) to (HIS126) CRYSTAL STRUCTURE OF A GLYCOSYLTRANSFERASE INVOLVED IN THE GLYCOSYLATION OF THE MAJOR CAPSID OF PBCV-1 | GLYCOSYLTRANSFERASE, PBCV, TRANSFERASE
4hg3:C (LEU122) to (SER144) STRUCTURAL INSIGHTS INTO YEAST NIT2: WILD-TYPE YEAST NIT2 IN COMPLEX WITH ALPHA-KETOGLUTARATE | NITRILASE SUPERFAMILY, OMEGA-AMIDASE, HYDROLASE
1b9m:A (ARG128) to (ALA161) REGULATOR FROM ESCHERICHIA COLI | DNA-BINDING, GENE REGULATION, WINGED HELIX TURN HELIX, MOLYBDATE, OB FOLD, TRANSCRIPTION
4wze:A (GLY428) to (LEU452) CRYSTAL STRUCTURE OF P DOMAIN FROM NOROVIRUS STRAIN SAGA4 IN COMPLEX WITH HBGA TYPE LEY (TETRAGLYCAN) | VIRAL PROTEIN, PROTRUDING DOMAIN
1ba3:A (ILE336) to (GLY394) FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM | OXIDOREDUCTASE, MONOOXYGENASE, PHOTOPROTEIN, LUMINESCENCE
4wzl:A (GLY428) to (LEU452) CRYSTAL STRUCTURE OF P DOMAIN FROM NOROVIRUS STRAIN SAGA4 IN COMPLEX WITH HBGA TYPE LEA (TRIGLYCAN) | VIRAL CAPSID PROTEIN, PROTRUDING DOMAIN, VIRAL PROTEIN
4wzl:B (GLY428) to (LEU452) CRYSTAL STRUCTURE OF P DOMAIN FROM NOROVIRUS STRAIN SAGA4 IN COMPLEX WITH HBGA TYPE LEA (TRIGLYCAN) | VIRAL CAPSID PROTEIN, PROTRUDING DOMAIN, VIRAL PROTEIN
2p8y:T (ARG564) to (PRO592) FITTED STRUCTURE OF ADPR-EEF2 IN THE 80S:ADPR- EEF2:GDP:SORDARIN CRYO-EM RECONSTRUCTION | ELONGATION, TRANSLOCATION, GTPASE, 80S RIBOSOME, TRANSLATION
2p8x:T (ARG564) to (PRO592) FITTED STRUCTURE OF ADPR-EEF2 IN THE 80S:ADPR-EEF2:GDPNP CRYO-EM RECONSTRUCTION | ELONGATION, TRANSLOCATION, GTPASE, 80S RIBOSOME, TRANSLATION
3ewj:A (LEU348) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TACE WITH CARBOXYLATE INHIBITOR | TACE, ADAM17, HYDROLASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, GLYCOPROTEIN, MEMBRANE, METAL-BINDING, METALLOPROTEASE, NOTCH SIGNALING PATHWAY, PHOSPHOPROTEIN, PROTEASE, SH3-BINDING, TRANSMEMBRANE, ZYMOGEN
2p8z:T (ARG564) to (PRO592) FITTED STRUCTURE OF ADPR-EEF2 IN THE 80S:ADPR- EEF2:GDPNP:SORDARIN CRYO-EM RECONSTRUCTION | ELONGATION, TRANSLOCATION, GTPASE, 80S RIBOSOME, TRANSLATION
3ewx:A (LEU413) to (SER434) K314A MUTANT OF HUMAN OROTIDYL-5'-MONOPHOSPHATE DECARBOXYLASE IN COMPLEX WITH 6-AZIDO-UMP, DEGRADED TO BMP | DECARBOXYLASE, TIM BARREL, UNUSUAL CATALYSIS, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
3ex1:A (LEU413) to (SER434) HUMAN OROTIDYL-5'-MONOPHOSPHATE DECARBOXYLASE SOAKED WITH 6-CYANO-UMP, CONVERTED TO UMP | DECARBOXYLASE, TIM BARREL, UNUSUAL CATALYSIS, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
3ex4:A (LEU413) to (SER434) HUMAN OROTIDYL-5'-MONOPHOSPHATE DECARBOXYLASE IN COMPLEX WITH BMP | DECARBOXYLASE, TIM BARREL, UNUSUAL CATALYSIS, ALTERNATIVE SPLICING, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, POLYMORPHISM, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
3ex6:B (LEU413) to (SER434) D312N MUTANT OF HUMAN OROTIDYL-5'-MONOPHOSPHATE DECARBOXYLASE IN COMPLEX WITH 6-AZIDO-UMP, COVALENT ADDUCT | DECARBOXYLASE, TIM BARREL, UNUSUAL CATALYSIS, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
4x07:A (GLY428) to (LEU452) CRYSTAL STRUCTURE OF P DOMAIN FROM NOROVIRUS STRAIN SAGA4 IN COMPLEX WITH HBGA TYPE A (TRIGLYCAN) | VIRAL CAPSID PROTEIN, PROTRUDING DOMAIN, VIRAL PROTEIN
4hib:A (LEU224) to (SER245) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH CMP-N4-OH | ALPA-BETA BARREL, TIM BARREL, DECARBOXYLASE, LYASE-LYASE INHIBITOR COMPLEX
4hit:A (PHE37) to (ASP81) CRYSTAL STRUCTURE OF H112W MUTANT OF BORNA DISEASE VIRUS MATRIX PROTEIN | VIRAL MATRIX PROTEIN, RNA BINDING, MEMBRANE BINDING, VIRUSES, SSRNA, NEGATIVE-STRAND VIRUSES, MONONEGAVIRALES, BORNAVIRIDAE, BORNA VIRUS, VIRION, VIRAL PROTEIN
2pbc:A (ASN73) to (LYS135) FK506-BINDING PROTEIN 2 | ENDOPLASMIC RETICULUM, ISOMERASE, POLYMORPHISM, ROTAMASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
2pbc:B (ASN73) to (LYS135) FK506-BINDING PROTEIN 2 | ENDOPLASMIC RETICULUM, ISOMERASE, POLYMORPHISM, ROTAMASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
2pbc:C (ASN73) to (LYS135) FK506-BINDING PROTEIN 2 | ENDOPLASMIC RETICULUM, ISOMERASE, POLYMORPHISM, ROTAMASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
3eyd:A (GLY140) to (ILE170) STRUCTURE OF HCV NS3-4A PROTEASE WITH AN INHIBITOR DERIVED FROM A BORONIC ACID | HEPATITIS C VIRUS, NS3 PROTEASE DOMAIN, SERINE PROTEASE, BORONIC ACID INHIBITOR, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, VIRAL PROTEIN
4x1s:U (GLY197) to (THR229) THE CRYSTAL STRUCTURE OF MUPAIN-1-16-D9A IN COMPLEX WITH MURINISED HUMAN UPA AT PH7.4 | SERINE PROTEASE, PEPTIDIC INHIBITOR, UPA, HYDROLASE INHIBITOR- HYDROLASE COMPLEX
2pcd:F (GLY119) to (ARG142) STRUCTURE OF PROTOCATECHUATE 3,4-DIOXYGENASE FROM PSEUDOMONAS AERUGINOSA AT 2.15 ANGSTROMS RESOLUTION | DIOXYGENASE
2pce:A (ARG5) to (HIS29) CRYSTAL STRUCTURE OF PUTATIVE MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME FROM ROSEOVARIUS NUBINHIBENS ISM | STRUCTURAL GENOMICS, ENOLASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, LYASE
2pce:G (ARG5) to (HIS29) CRYSTAL STRUCTURE OF PUTATIVE MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME FROM ROSEOVARIUS NUBINHIBENS ISM | STRUCTURAL GENOMICS, ENOLASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, LYASE
3ezy:D (GLY246) to (SER269) CRYSTAL STRUCTURE OF PROBABLE DEHYDROGENASE TM_0414 FROM THERMOTOGA MARITIMA | STRUCTURAL GENOMICS, UNKNOWN FUNCTION, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
4hmc:A (VAL33) to (CYS53) CRYSTAL STRUCTURE OF COLD-ADAPTED CHITINASE FROM MORITELLA MARINA | CHITINASE, HYDROLAZE, TIM-BARREL, IG-LIKE, IMMUNOGLOBULIN LIKE DOMAIN, CHBD, CHITIN BINDING DOMAIN, HYDROLASE
4hmd:A (VAL33) to (PRO52) CRYSTAL STRUCTURE OF COLD-ADAPTED CHITINASE FROM MORITELLA MARINA WITH A REACTION INTERMEDIATE - OXAZOLINIUM ION (NGO) | CHITINASE, HYDROLAZE, TIM-BARREL, IG-LIKE, IMMUNOGLOBULIN LIKE DOMAIN, CHB D, CHITIN BINDING DOMAIN, HYDROLASE
4hme:A (VAL33) to (CYS53) CRYSTAL STRUCTURE OF COLD-ADAPTED CHITINASE FROM MORITELLA MARINA WITH A REACTION PRODUCT - NAG2 | CHITINASE, HYDROLAZE, TIM-BARREL, IG-LIKE, IMMUNOGLOBULIN LIKE DOMAIN, CHBD, CHITIN BINDING DOMAIN, HYDROLASE
1o23:B (ASP254) to (SER297) CRYSTAL STRUCTURE OF LACTOSE SYNTHASE IN THE PRESENCE OF UDP-GLUCOSE | ALPHA-LACTALBUMIN; BETA,1,4-GALACTOSYLTRANSFERASE; UDP-GLUCOSE, TRANSFERASE ACTIVATOR-TRANSFERASE COMPLEX
1o23:D (ASP656) to (SER699) CRYSTAL STRUCTURE OF LACTOSE SYNTHASE IN THE PRESENCE OF UDP-GLUCOSE | ALPHA-LACTALBUMIN; BETA,1,4-GALACTOSYLTRANSFERASE; UDP-GLUCOSE, TRANSFERASE ACTIVATOR-TRANSFERASE COMPLEX
1bkc:C (LEU348) to (ASN381) CATALYTIC DOMAIN OF TNF-ALPHA CONVERTING ENZYME (TACE) | ZN-ENDOPEPTIDASE, HYDROLASE, TNF-ALPHA
1bkc:E (LEU348) to (ASN381) CATALYTIC DOMAIN OF TNF-ALPHA CONVERTING ENZYME (TACE) | ZN-ENDOPEPTIDASE, HYDROLASE, TNF-ALPHA
1o5a:B (GLY197) to (THR229) DISSECTING AND DESIGNING INHIBITOR SELECTIVITY DETERMINANTS AT THE S1 SITE USING AN ARTIFICIAL ALA190 PROTEASE (ALA190 UPA) | ALA190 UPA, S1 SITE, SELECTIVITY, CONSERVED WATER DISPLACEMENT HYDROGEN BOND DEFICIT, TRYPSIN, THROMBIN, HEPSIN, FACTOR VIIA, BLOOD CLOTTING, HYDROLASE
1o5b:B (GLY197) to (THR229) DISSECTING AND DESIGNING INHIBITOR SELECTIVITY DETERMINANTS AT THE S1 SITE USING AN ARTIFICIAL ALA190 PROTEASE (ALA190 UPA) | ALA190 UPA, S1 SITE, SELECTIVITY, CONSERVED WATER DISPLACEMENT HYDROGEN BOND DEFICIT, TRYPSIN, THROMBIN, HEPSIN, FACTOR VIIA, BLOOD CLOTTING, HYDROLASE
1o5c:B (GLY197) to (THR229) DISSECTING AND DESIGNING INHIBITOR SELECTIVITY DETERMINANTS AT THE S1 SITE USING AN ARTIFICIAL ALA190 PROTEASE (ALA190 UPA) | ALA190 UPA, S1 SITE, SELECTIVITY, CONSERVED WATER DISPLACEMENT HYDROGEN BOND DEFICIT, TRYPSIN, THROMBIN, HEPSIN, FACTOR VIIA, BLOOD CLOTTING, HYDROLASE
3s5s:A (ARG9) to (ARG32) CRYSTAL STRUCTURE OF PUTATIVE MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME (PSI/COM TARGET 200551) FROM SORANGIUM CELLULOSUM | PSI-BIOLOGY, STRUCTURAL GENOMICS, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, ISOMERASE
4x67:B (GLY902) to (LEU941) CRYSTAL STRUCTURE OF ELONGATING YEAST RNA POLYMERASE II STALLED AT OXIDATIVE CYCLOPURINE DNA LESIONS. | POL II ELONGATION COMPLEX OXIDATIVE CYCLOPURINE DNA LESIONS, TRANSCRIPTION-DNA COMPLEX
4x67:B (THR944) to (PRO974) CRYSTAL STRUCTURE OF ELONGATING YEAST RNA POLYMERASE II STALLED AT OXIDATIVE CYCLOPURINE DNA LESIONS. | POL II ELONGATION COMPLEX OXIDATIVE CYCLOPURINE DNA LESIONS, TRANSCRIPTION-DNA COMPLEX
4hpn:A (VAL6) to (ARG28) CRYSTAL STRUCTURE OF A PROPOSED GALACTAROLACTONE CYCLOISOMERASE FROM AGROBACTERIUM TUMEFACIENS, TARGET EFI-500704, WITH BOUND CA, ORDERED LOOPS | ENOLASE, ENZYME FUNCTION INITIATIVE, EFI, STRUCTURAL GENOMICS, ISOMERASE
4x8v:H (THR206) to (THR229) FACTOR VIIA IN COMPLEX WITH THE INHIBITOR (METHYL {3-[(2R)-1-{(2R)-2- (3,4-DIMETHOXYPHENYL)-2-[(1-OXO-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL) AMINO]ACETYL}PYRROLIDIN-2-YL]-4-(PROPAN-2-YLSULFONYL) PHENYL}CARBAMATE) | GLYCOPROTEIN, HYDROLASE, SERINE PROTEASE, PLASMA, BLOOD COAGULATION FACTOR, PROTEIN INHIBITOR COMPLEX, CALCIUM- BINDING
3fce:A (LEU391) to (GLU410) CRYSTAL STRUCTURE OF BACILLUS CEREUS D-ALANYL CARRIER PROTEIN LIGASE DLTA IN COMPLEX WITH ATP: IMPLICATIONS FOR ADENYLATION MECHANISM | DLTA, AMP-FORMING DOMAIN, D-ALANINE, ADENYLATION, D-ALANINE CARRIER PROTEIN LIGASE, ATP COMPLEX, LIGASE
4hvs:A (ASN787) to (ILE808) CRYSTAL STRUCTURE OF KIT KINASE DOMAIN WITH A SMALL MOLECULE INHIBITOR, PLX647 | TRANSFERASE, TYROSINE-PROTEIN KINASE, ATP-BINDING, KINASE-KINASE INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1c1o:A (GLY197) to (THR229) RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES | ZN(II)-MEDIATED SERINE PROTEASE INHIBITORS, PH DEPENDENCE, ZN(II) AFFINITY STUCTURE-BASED DRUG DESIGN, SERINE PROTEASE SERINE PROTEASE/INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1c1s:A (GLY197) to (THR229) RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES | ZN(II)-MEDIATED SERINE PROTEASE INHIBITORS, PH DEPENDENCE, ZN(II) AFFINITY STUCTURE-BASED DRUG DESIGN, SERINE PROTEASE/INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1c2k:A (GLY197) to (THR229) RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES | ZN(II)-MEDIATED SERINE PROTEASE INHIBITORS, PH DEPENDENCE, ZN(II) AFFINITY STUCTURE-BASED DRUG DESIGN, SERINE PROTEASE/INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1og0:A (THR311) to (GLY346) CRYSTAL STRUCTURE OF THE MUTANT G226S OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH PHENYLALANINE AND MANGANESE | BETA-ALPHA-BARREL, LYASE
1c5w:B (GLY197) to (THR229) STRUCTURAL BASIS FOR SELECTIVITY OF A SMALL MOLECULE, S1- BINDING, SUB-MICROMOLAR INHIBITOR OF UROKINASE TYPE PLASMINOGEN ACTIVATOR | SELECTIVE, S1 SITE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, UROKINASE, TRYPSIN, THROMBIN, BLOOD CLOTTING
1c5x:B (GLY197) to (THR229) STRUCTURAL BASIS FOR SELECTIVITY OF A SMALL MOLECULE, S1- BINDING, SUB-MICROMOLAR INHIBITOR OF UROKINASE TYPE PLASMINOGEN ACTIVATOR | SELECTIVE, S1 SITE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, UROKINASE, TRYPSIN, THROMBIN, BLOOD CLOTTING
1c5y:B (GLY197) to (THR229) STRUCTURAL BASIS FOR SELECTIVITY OF A SMALL MOLECULE, S1- BINDING, SUB-MICROMOLAR INHIBITOR OF UROKINASE TYPE PLASMINOGEN ACTIVATOR | SELECTIVE, S1 SITE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, UROKINASE, TRYPSIN, THROMBIN, BLOOD CLOTTING
3sgb:E (GLY196) to (GLN229) STRUCTURE OF THE COMPLEX OF STREPTOMYCES GRISEUS PROTEASE B AND THE THIRD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR AT 1.8 ANGSTROMS RESOLUTION | COMPLEX(SERINE PROTEINASE-INHIBITOR)
4i31:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3/NS4A PROTEASE COMPLEXED WITH COMPOUND 4 | HEPATITIS C VIRUS, NS3, NS4A, PROTEIN-INHIBITOR COMPLEX COMPOUND 4, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4i31:B (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3/NS4A PROTEASE COMPLEXED WITH COMPOUND 4 | HEPATITIS C VIRUS, NS3, NS4A, PROTEIN-INHIBITOR COMPLEX COMPOUND 4, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4i32:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3/4A D168V PROTEASE COMPLEXED WITH COMPOUND 4 | HEPATITIS C VIRUS, NS3, NS4A, PROTEIN-INHIBITOR COMPLEX COMPOUND 4, SERINE PROTEASE, D168V, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4i32:B (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3/4A D168V PROTEASE COMPLEXED WITH COMPOUND 4 | HEPATITIS C VIRUS, NS3, NS4A, PROTEIN-INHIBITOR COMPLEX COMPOUND 4, SERINE PROTEASE, D168V, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4i33:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3/4A R155K PROTEASE COMPLEXED WITH COMPOUND 4 | HEPATITIS C VIRUS, NS3, NS4A, PROTEIN-INHIBITOR COMPLEX COMPOUND 4, SERINE PROTEASE, R155K, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4i33:B (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3/4A R155K PROTEASE COMPLEXED WITH COMPOUND 4 | HEPATITIS C VIRUS, NS3, NS4A, PROTEIN-INHIBITOR COMPLEX COMPOUND 4, SERINE PROTEASE, R155K, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ca0:C (ALA179) to (GLY211) BOVINE CHYMOTRYPSIN COMPLEXED TO APPI | SERINE PROTEASE, INHIBITOR, PROTEASE-SUBSTRATE INTERACTIONS, COMPLEX (SERINE PROTEASE/INHIBITOR)
1ca0:H (ALA179) to (GLY211) BOVINE CHYMOTRYPSIN COMPLEXED TO APPI | SERINE PROTEASE, INHIBITOR, PROTEASE-SUBSTRATE INTERACTIONS, COMPLEX (SERINE PROTEASE/INHIBITOR)
2ppg:A (LYS6) to (PHE49) CRYSTAL STRUCTURE OF PUTATIVE ISOMERASE FROM SINORHIZOBIUM MELILOTI | STRUCTURAL GENOMICS, ISOMERASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
2ppg:B (LYS7) to (PHE49) CRYSTAL STRUCTURE OF PUTATIVE ISOMERASE FROM SINORHIZOBIUM MELILOTI | STRUCTURAL GENOMICS, ISOMERASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
1cb5:A (ASP266) to (ASN302) HUMAN BLEOMYCIN HYDROLASE. | HYDROLASE, AMINOPEPTIDASE, CYSTEINE PROTEASE, SELF- COMPARTMENTALIZING, BLEOMYCIN
1cb5:B (ASP266) to (ASN302) HUMAN BLEOMYCIN HYDROLASE. | HYDROLASE, AMINOPEPTIDASE, CYSTEINE PROTEASE, SELF- COMPARTMENTALIZING, BLEOMYCIN
1cb5:C (ASP266) to (ASN302) HUMAN BLEOMYCIN HYDROLASE. | HYDROLASE, AMINOPEPTIDASE, CYSTEINE PROTEASE, SELF- COMPARTMENTALIZING, BLEOMYCIN
2pxz:X (GLY227) to (GLY248) E. COLI PHOSPHOENOLPYRUVATE CARBOXYKINASE (PEPCK) COMPLEXED WITH ATP, MG2+, MN2+, CARBON DIOXIDE AND OXALOACETATE | P-LOOP, OXALOACETATE, CARBON DIOXIDE, CO2, LYASE
3fp9:B (ASP181) to (ALA236) CRYSTAL STRUCTURE OF INTERN DOMAIN OF PROTEASOME-ASSOCIATED ATPASE, MYCOBACTERIUM TUBERCULOSIS | FIVE STRAND BETA BARREL, HEXAMER, ATP-BINDING, NUCLEOTIDE- BINDING, HYDROLASE, AAA ATPASE, PROTEASOMAL ATPASE
3fp9:J (ASP181) to (ALA236) CRYSTAL STRUCTURE OF INTERN DOMAIN OF PROTEASOME-ASSOCIATED ATPASE, MYCOBACTERIUM TUBERCULOSIS | FIVE STRAND BETA BARREL, HEXAMER, ATP-BINDING, NUCLEOTIDE- BINDING, HYDROLASE, AAA ATPASE, PROTEASOMAL ATPASE
3fqg:A (SER153) to (CYS202) CRYSTAL STRUCTURE OF THE S. POMBE RAI1 | HYDROLASE, MRNA PROCESSING, NUCLEUS, PHOSPHOPROTEIN, RRNA PROCESSING, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSCRIPTION TERMINATION, PROTEIN BINDING
1cr5:A (ASN43) to (THR67) N-TERMINAL DOMAIN OF SEC18P | DOUBLE-PSI BETA BARREL, VESICLE FUSION, ENDOCYTOSIS/EXOCYTOSIS COMPLEX
1cr5:B (ASN43) to (THR67) N-TERMINAL DOMAIN OF SEC18P | DOUBLE-PSI BETA BARREL, VESICLE FUSION, ENDOCYTOSIS/EXOCYTOSIS COMPLEX
1owk:A (LYS179) to (GLY213) SUBSTITUTED 2-NAPHTHAMIDINE INHIBITORS OF UROKINASE | PLASMINOGEN ACTIVATION, HYDROLASE, SERINE PROTEASE, GLYCOPROTEIN, KRINGLE, EGF-LIKE DOMAIN
1csk:C (GLN26) to (PRO61) THE CRYSTAL STRUCTURE OF HUMAN CSKSH3: STRUCTURAL DIVERSITY NEAR THE RT-SRC AND N-SRC LOOP | PHOSPHOTRANSFERASE
1ct0:E (GLY196) to (GLN229) CRYSTAL STRUCTURE OF THE OMTKY3 P1 VARIANT OMTKY3-SER18I IN COMPLEX WITH SGPB | ENZYME-INHIBITOR COMPLEX, BETA-BRANCHED P1 RESIDUE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1ct2:E (GLY196) to (GLN229) CRYSTAL STRUCTURE OF THE OMTKY3 P1 VARIANT OMTKY3-THR18I IN COMPLEX WITH SGPB | ENZYME-INHIBITOR COMPLEX, BETA-BRANCHED P1 RESIDUE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1ct4:E (GLY196) to (GLN229) CRYSTAL STRUCTURE OF THE OMTKY3 P1 VARIANT OMTKY3-VAL18I IN COMPLEX WITH SGPB | ENZYME-INHIBITOR COMPLEX, BETA-BRANCHED P1 RESIDUE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1cu1:A (GLY140) to (VAL170) CRYSTAL STRUCTURE OF AN ENZYME COMPLEX FROM HEPATITIS C VIRUS | HEPATITIS C VIRUS, BIFUNCTIONAL,PROTEASE-HELICASE, HYDROLASE
3su1:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT D168A IN COMPLEX WITH DANOPREVIR | NS3, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3su0:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT R155K IN COMPLEX WITH DANOPREVIR | NS3, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3su2:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT A156T IN COMPLEX WITH DANOPREVIR | NS3, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3su3:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE IN COMPLEX WITH VANIPREVIR | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3su4:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT R155K IN COMPLEX WITH VANIPREVIR | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3su4:B (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT R155K IN COMPLEX WITH VANIPREVIR | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3su5:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT D168A IN COMPLEX WITH VANIPREVIR | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3su6:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT A156T IN COMPLEX WITH VANIPREVIR | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3sud:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE IN COMPLEX WITH MK-5172 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3sud:B (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE IN COMPLEX WITH MK-5172 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3sud:C (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE IN COMPLEX WITH MK-5172 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3sud:D (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE IN COMPLEX WITH MK-5172 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3sue:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT R155K IN COMPLEX WITH MK- 5172 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3sue:B (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT R155K IN COMPLEX WITH MK- 5172 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3sue:C (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT R155K IN COMPLEX WITH MK- 5172 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3sue:D (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT R155K IN COMPLEX WITH MK- 5172 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3suf:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT D168A IN COMPLEX WITH MK- 5172 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3suf:B (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT D168A IN COMPLEX WITH MK- 5172 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3suf:C (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT D168A IN COMPLEX WITH MK- 5172 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3suf:D (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT D168A IN COMPLEX WITH MK- 5172 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3sug:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT A156T IN COMPLEX WITH MK- 5172 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
2cb5:A (ASP266) to (ASN301) HUMAN BLEOMYCIN HYDROLASE, C73S/DELE455 MUTANT | HYDROLASE, AMINOPEPTIDASE, CYSTEINE PROTEASE, SELF- COMPARTMENTALIZING, BLEOMYCIN, CYLINASE
2cb5:B (ASP266) to (ASN302) HUMAN BLEOMYCIN HYDROLASE, C73S/DELE455 MUTANT | HYDROLASE, AMINOPEPTIDASE, CYSTEINE PROTEASE, SELF- COMPARTMENTALIZING, BLEOMYCIN, CYLINASE
3sv6:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE IN COMPLEX WITH TELAPREVIR | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, SERINE PROTEASE, HYDROLASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3sv7:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT R155K IN COMPLEX WITH TELAPREVIR | NS3, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, HCV, SERINE PROTEASE, HYDROLASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3sv8:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT D168A IN COMPLEX WITH TELAPREVIR | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, SERINE PROTEASE, HYDROLASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
3sv9:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF NS3/4A PROTEASE VARIANT A156T IN COMPLEX WITH TELAPREVIR | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, SERINE PROTEASE, HYDROLASE, VIRAL PROTEIN, HYDROLASE-INHIBITOR COMPLEX
1p2m:C (ALA179) to (GLY211) STRUCTURAL CONSEQUENCES OF ACCOMMODATION OF FOUR NON- COGNATE AMINO-ACID RESIDUES IN THE S1 POCKET OF BOVINE TRYPSIN AND CHYMOTRYPSIN | TRYPSIN; CHYMOTRYPSIN; SERINE PROTEINASE; BOVINE PANCREATIC TRYPSIN INHIBITOR; PROTEIN-PROTEIN INTERACTION; NON-COGNATE BINDING; S1 POCKET; PRIMARY SPECIFICITY; CRYSTAL STRUCTURE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1p2n:C (ALA179) to (GLY211) STRUCTURAL CONSEQUENCES OF ACCOMMODATION OF FOUR NON- COGNATE AMINO-ACID RESIDUES IN THE S1 POCKET OF BOVINE TRYPSIN AND CHYMOTRYPSIN | TRYPSIN; CHYMOTRYPSIN; SERINE PROTEINASE; BOVINE PANCREATIC TRYPSIN INHIBITOR; PROTEIN-PROTEIN INTERACTION; NON-COGNATE BINDING; S1 POCKET; PRIMARY SPECIFICITY; CRYSTAL STRUCTURE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1p2q:A (ALA179) to (GLY211) STRUCTURAL CONSEQUENCES OF ACCOMMODATION OF FOUR NON- COGNATE AMINO-ACID RESIDUES IN THE S1 POCKET OF BOVINE TRYPSIN AND CHYMOTRYPSIN | TRYPSIN; CHYMOTRYPSIN; SERINE PROTEINASE; BOVINE PANCREATIC TRYPSIN INHIBITOR; PROTEIN-PROTEIN INTERACTION; NON-COGNATE BINDING; S1 POCKET; PRIMARY SPECIFICITY; CRYSTAL STRUCTURE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1p2q:C (ALA179) to (GLY211) STRUCTURAL CONSEQUENCES OF ACCOMMODATION OF FOUR NON- COGNATE AMINO-ACID RESIDUES IN THE S1 POCKET OF BOVINE TRYPSIN AND CHYMOTRYPSIN | TRYPSIN; CHYMOTRYPSIN; SERINE PROTEINASE; BOVINE PANCREATIC TRYPSIN INHIBITOR; PROTEIN-PROTEIN INTERACTION; NON-COGNATE BINDING; S1 POCKET; PRIMARY SPECIFICITY; CRYSTAL STRUCTURE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3swz:D (PRO372) to (LYS388) HUMAN CYTOCHROME P450 17A1 IN COMPLEX WITH TOK-001 | CYTOCHROME P450, P450, CYP17A1, P450C17, P450 17A1, MONOOXYGENASE, 17A-HYDROXYLASE, 17,20-LYASE, HEME PROTEIN, CYTOCHROME P450 OXIDOREDUCTASE, GALETERONE, MEMBRANE, TOK-001, VN/124-1, MICROSOME, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
2qa9:E (GLY196) to (GLN229) CRYSTAL STRUCTURE OF THE SECOND TETRAHEDRAL INTERMEDIATES OF SGPB AT PH 4.2 | CHYMOTRYPSIN-TYPE SERINE PEPTIDASE, SECOND TETRAHEDRAL INTERMEDIATE, TETRAPEPTIDE, BETA BARRELS, ALPHA HELIX, HYDROLASE
2qaa:A (THR64) to (ARG107) CRYSTAL STRUCTURE OF THE SECOND TETRAHEDRAL INTERMEDIATES OF SGPB AT PH 7.3 | CHYMOTRYPSIN-TYPE SERINE PEPTIDASE, SECOND TETRAHEDRAL INTERMEDIATES, SINGLE AMINO ACIDS, BETA BARRELS, ALPHA HELIX, HYDROLASE
2qaa:B (THR64) to (ARG107) CRYSTAL STRUCTURE OF THE SECOND TETRAHEDRAL INTERMEDIATES OF SGPB AT PH 7.3 | CHYMOTRYPSIN-TYPE SERINE PEPTIDASE, SECOND TETRAHEDRAL INTERMEDIATES, SINGLE AMINO ACIDS, BETA BARRELS, ALPHA HELIX, HYDROLASE
3g0e:A (ASN787) to (ILE808) KIT KINASE DOMAIN IN COMPLEX WITH SUNITINIB | KIT KINASE DOMAIN, SUTENT BINDING, DRUG RESISTANCE, ATP- BINDING, DISEASE MUTATION, GLYCOPROTEIN, IMMUNOGLOBULIN DOMAIN, KINASE, MEMBRANE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, POLYMORPHISM, PROTO-ONCOGENE, RECEPTOR, TRANSMEMBRANE, TYROSINE-PROTEIN KINASE, TRANSFERASE
4xob:A (ALA115) to (ASN152) CRYSTAL STRUCTURE OF A FIMH*DSF COMPLEX FROM E.COLI K12 WITH BOUND HEPTYL ALPHA-D-MANNOPYRANNOSIDE | FOLDASE, PROLYL ISOMERASE, PROTEIN SECRETION, GRAM-POSITIVE, ISOMERASE, CELL ADHESION
4xob:C (ALA115) to (ASN152) CRYSTAL STRUCTURE OF A FIMH*DSF COMPLEX FROM E.COLI K12 WITH BOUND HEPTYL ALPHA-D-MANNOPYRANNOSIDE | FOLDASE, PROLYL ISOMERASE, PROTEIN SECRETION, GRAM-POSITIVE, ISOMERASE, CELL ADHESION
2qcd:A (LEU413) to (SER434) CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE BOUND TO UMP | UMP SYNTHASE, DECARBOXYLASE, CATALYTIC PROFICIENCY, LYASE
2qce:A (LEU413) to (SER434) CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE BOUND TO SULFATE, GLYCEROL, AND CHLORIDE | UMP SYNTHASE, DECARBOXYLASE, CATALYTIC PROFICIENCY, LYASE
2qch:A (LEU413) to (SER434) CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE BOUND TO 5-IODO-UMP | UMP SYNTHASE, DECARBOXYLASE, CATALYTIC PROFICIENCY, LYASE
2qch:B (LEU413) to (SER434) CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE BOUND TO 5-IODO-UMP | UMP SYNTHASE, DECARBOXYLASE, CATALYTIC PROFICIENCY, LYASE
2qcm:A (LEU413) to (SER434) CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN (ASP312ASN MUTANT) OF HUMAN UMP SYNTHASE BOUND TO 6-HYDROXYMETHYL-UMP | UMP SYNTHASE, DECARBOXYLASE, CATALYTIC PROFICIENCY, LYASE
2cga:A (ALA179) to (GLY211) BOVINE CHYMOTRYPSINOGEN A. X-RAY CRYSTAL STRUCTURE ANALYSIS AND REFINEMENT OF A NEW CRYSTAL FORM AT 1.8 ANGSTROMS RESOLUTION | HYDROLASE(ZYMOGEN)
3g3d:A (LEU224) to (SER245) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 5-FLUORO-6-AZIDO-UMP | UMP SYNTHASE, C-TERMINAL DOMAIN, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, HUMAN, 5-FLUORO-6-AZIDO-UMP, DECARBOXYLASE, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PHOSPHOPROTEIN, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
2ch8:D (SER39) to (HIS65) STRUCTURE OF THE EPSTEIN-BARR VIRUS ONCOGENE BARF1 | VIRAL PROTEIN, BARF1, IMMUNOGLOBULIN DOMAIN, ONCOGENE, EARLY PROTEIN
2qf0:D (GLY202) to (ILE236) STRUCTURE OF THE DELTA PDZ TRUNCATION OF THE DEGS PROTEASE | DEGS, PROTEASE, PERIPLASMIC STRESS SENSOR, HTRA, ALLOSTERIC ACTIVATION, HYDROLASE
3g3m:A (LEU224) to (SER245) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 5-FLUORO-6-IODO-UMP | HUMAN, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, C-TERMINAL DOMAIN, 5-FLUORO-6-IODO-UMP, ALTERNATIVE SPLICING, DECARBOXYLASE, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PHOSPHOPROTEIN, POLYMORPHISM, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
2qf4:A (ASN143) to (ASN167) HIGH RESOLUTION STRUCTURE OF THE MAJOR PERIPLASMIC DOMAIN FROM THE CELL SHAPE-DETERMINING FILAMENT MREC (ORTHORHOMBIC FORM) | FILAMENT A-LYTIC PROTEASE FOLD, STRUCTURAL PROTEIN
2qf4:A (ASP218) to (LYS255) HIGH RESOLUTION STRUCTURE OF THE MAJOR PERIPLASMIC DOMAIN FROM THE CELL SHAPE-DETERMINING FILAMENT MREC (ORTHORHOMBIC FORM) | FILAMENT A-LYTIC PROTEASE FOLD, STRUCTURAL PROTEIN
2qf5:A (ASN143) to (ASN167) HIGH RESOLUTION STRUCTURE OF THE MAJOR PERIPLASMIC DOMAIN FROM THE CELL SHAPE-DETERMINING FILAMENT MREC (MONOCLINIC FORM) | FILAMENT A-LYTIC PROTEASE FOLD, STRUCTURAL PROTEIN
1p8v:C (ARG218) to (THR241) CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A | PLATELET GLYCOPROTEIN RECEPTOR, LEUCINE RICH REPEAT DOMAIN, MEMBRANE PROTEIN-HYDROLASE COMPLEX
1pbc:A (ASP68) to (ASP87) CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY- 4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2- HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING | OXIDOREDUCTASE
4ink:A (ASP48) to (GLU85) CRYSTAL STRUCTURE OF SPLD PROTEASE FROM STAPHYLOCOCCUS AUREUS AT 1.56 A RESOLUTION | CHYMOTRYPSIN-LIKE PROTEASE, SERINE ENDOPEPTIDASE, EXTRACELLULAR STAPHYLOCOCCAL PROTEASES, HYDROLASE
4ink:A (GLY157) to (VAL187) CRYSTAL STRUCTURE OF SPLD PROTEASE FROM STAPHYLOCOCCUS AUREUS AT 1.56 A RESOLUTION | CHYMOTRYPSIN-LIKE PROTEASE, SERINE ENDOPEPTIDASE, EXTRACELLULAR STAPHYLOCOCCAL PROTEASES, HYDROLASE
4inl:A (GLY157) to (VAL187) CRYSTAL STRUCTURE OF SPLD PROTEASE FROM STAPHYLOCOCCUS AUREUS AT 2.1 A RESOLUTION | CHYMOTRYPSIN-LIKE PROTEASE, SERINE ENDOPEPTIDASE, EXTRACELLULAR STAPHYLOCOCCAL PROTEASES, HYDROLASE
1dit:H (ARG206) to (THR229) COMPLEX OF A DIVALENT INHIBITOR WITH THROMBIN | HYDROLASE, BLOOD COAGULATION, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1dle:A (ILE64) to (LYS107) FACTOR B SERINE PROTEASE DOMAIN | SERINE PROTEASE, COMPLEMENT SYSTEM, FACTOR B, PROTEIN- PROTEIN INTERACTION, ACTIVATION MECHANISM, BETA-BARREL FOLD, , HYDROLASE
1dle:B (ILE64) to (LYS107) FACTOR B SERINE PROTEASE DOMAIN | SERINE PROTEASE, COMPLEMENT SYSTEM, FACTOR B, PROTEIN- PROTEIN INTERACTION, ACTIVATION MECHANISM, BETA-BARREL FOLD, , HYDROLASE
3gch:C (ALA179) to (GLY211) CHEMISTRY OF CAGED ENZYMES. BINDING OF PHOTOREVERSIBLE CINNAMATES TO CHYMOTRYPSIN | HYDROLASE (SERINE PROTEINASE)
4irq:B (ASP165) to (SER207) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN BETA1, 4GALACTOSYLTRANSFERASE 7 IN CLOSED CONFORMATION IN COMPLEX WITH MANGANESE AND UDP | GT-A FOLD, CLOSED CONFORMATION, MANGANESE AND UDP COMPLEX, GLYCOSYLTRANSFERASE, GOLGI, TRANSFERASE
4irq:C (ASP165) to (SER207) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN BETA1, 4GALACTOSYLTRANSFERASE 7 IN CLOSED CONFORMATION IN COMPLEX WITH MANGANESE AND UDP | GT-A FOLD, CLOSED CONFORMATION, MANGANESE AND UDP COMPLEX, GLYCOSYLTRANSFERASE, GOLGI, TRANSFERASE
4irz:A (GLN66) to (CYS111) CRYSTAL STRUCTURE OF A4B7 HEADPIECE COMPLEXED WITH FAB NATALIZUMAB | ROLLING AND FIRM ADHESION, MADCAM, IMMUNE SYSTEM
1dob:A (ASP68) to (ASP87) THE MOBIL FLAVIN OF 4-OH BENZOATE HYDROXYLASE: MOTION OF A PROSTHETIC GROUP REGULATES CATALYSIS | OXIDOREDUCTASE
1dod:A (ASP68) to (ASP87) THE MOBIL FLAVIN OF 4-OH BENZOATE HYDROXYLASE: MOTION OF A PROSTHETIC GROUP REGULATES CATALYSIS | OXIDOREDUCTASE
3gdv:C (GLY202) to (ILE236) CRYSTAL STRUCTURE OF DEGS H198P/D320A MUTANT MODIFIED BY DFP AND IN COMPLEX WITH YQF PEPTIDE | PROTEASE, STRESS-SENSOR, HTRA, PDZ OMP, HYDROLASE, PERIPLASM, SERINE PROTEASE, HYDROLASE/HYDROLASE ACTIVATOR COMPLEX
4iuu:B (CYS202) to (ARG237) CRYSTAL STRUCTURE OF SHH1 SAWADEE DOMAIN IN COMPLEX WITH H3K9ME1 PEPTIDE | TANDEM TUDOR, ZINC FINGER, H3K9ME2, MEDIATE INTERACTION, HISTONE, METHYLATION, GENE REGULATION
3gis:F (ARG206) to (THR229) CRYSTAL STRUCTURE OF NA-FREE THROMBIN IN COMPLEX WITH THROMBOMODULIN | PROTEIN-PROTEIN COMPLEX, COAGULATION, ACUTE PHASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, DISULFIDE BOND, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, KRINGLE, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, EGF-LIKE DOMAIN, HYDROXYLATION, MEMBRANE, RECEPTOR, THROMBOPHILIA, TRANSMEMBRANE, BLOOD CLOTTING
1ppf:E (SER197) to (ALA229) X-RAY CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN LEUKOCYTE ELASTASE (PMN ELASTASE) AND THE THIRD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ppg:E (SER197) to (ALA229) THE REFINED 2.3 ANGSTROMS CRYSTAL STRUCTURE OF HUMAN LEUKOCYTE ELASTASE IN A COMPLEX WITH A VALINE CHLOROMETHYL KETONE INHIBITOR | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1dwc:H (ARG206) to (THR229) CRYSTALLOGRAPHIC ANALYSIS AT 3.0-ANGSTROMS RESOLUTION OF THE BINDING TO HUMAN THROMBIN OF FOUR ACTIVE SITE-DIRECTED INHIBITORS | SERINE PROTEINASE, HYDROLASE-HYROLASE INHIBITOR COMPLEX
1dxp:A (GLY140) to (ILE170) INHIBITION OF THE HEPATITIS C VIRUS NS3/4A PROTEASE. THE CRYSTAL STRUCTURES OF TWO PROTEASE-INHIBITOR COMPLEXES (APO STRUCTURE) | SERINE PROTEASE, NS3, NS4A, HEPATITIS C VIRUS, PROTEASE INHIBITION, HYDROLASE
1dxp:B (GLY140) to (ILE170) INHIBITION OF THE HEPATITIS C VIRUS NS3/4A PROTEASE. THE CRYSTAL STRUCTURES OF TWO PROTEASE-INHIBITOR COMPLEXES (APO STRUCTURE) | SERINE PROTEASE, NS3, NS4A, HEPATITIS C VIRUS, PROTEASE INHIBITION, HYDROLASE
1dy8:A (GLY140) to (ILE170) INHIBITION OF THE HEPATITIS C VIRUS NS3/4A PROTEASE. THE CRYSTAL STRUCTURES OF TWO PROTEASE-INHIBITOR COMPLEXES (INHIBITOR II) | SERINE PROTEASE, PROTEASE INHIBITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1dy8:B (GLY140) to (ILE170) INHIBITION OF THE HEPATITIS C VIRUS NS3/4A PROTEASE. THE CRYSTAL STRUCTURES OF TWO PROTEASE-INHIBITOR COMPLEXES (INHIBITOR II) | SERINE PROTEASE, PROTEASE INHIBITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1dyo:B (TYR10) to (ASN48) XYLAN-BINDING DOMAIN FROM CBM 22, FORMALLY X6B DOMAIN | CARBOHYDRATE-BINDING MODULE, XYLAN-BINDING, XYLANASE
2qv1:A (GLY166) to (ILE196) CRYSTAL STRUCTURE OF HCV NS3-4A V36M MUTANT | HCV, PROTEASE, NS3-4A, V36M MUTNAT, CRYSTAL STRUCTURE, HYDROLASE
2qv1:B (GLY1166) to (ILE1196) CRYSTAL STRUCTURE OF HCV NS3-4A V36M MUTANT | HCV, PROTEASE, NS3-4A, V36M MUTNAT, CRYSTAL STRUCTURE, HYDROLASE
3gni:B (GLY190) to (LEU211) STRUCTURE OF STRAD AND MO25 | KINASE FOLD, PSEUDOKINASE, ALPHA HELICAL REPEAT PROTEIN, ADAPTOR PROTEIN, ATP-BINDING, CELL CYCLE, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, METAL BINDING PROTEIN- TRANSFERASE COMPLEX, SIGNALING PROTEIN-SIGNALING PROTEIN COMPLEX
2qya:D (ASP13) to (ILE38) CRYSTAL STRUCTURE OF AN UNCHARACTERIZED CONSERVED PROTEIN FROM METHANOPYRUS KANDLERI | STRUCTURAL GENOMICS, UNKNOWN FUNCTION, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
3gqb:A (ASP26) to (GLN50) CRYSTAL STRUCTURE OF THE A3B3 COMPLEX FROM V-ATPASE | A3B3, V-ATPASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, HYDROLASE, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
3gqb:C (ASP26) to (GLN50) CRYSTAL STRUCTURE OF THE A3B3 COMPLEX FROM V-ATPASE | A3B3, V-ATPASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, HYDROLASE, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
3gqh:B (HIS796) to (LYS854) CRYSTAL STRUCTURE OF THE BACTERIOPHAGE PHI29 GENE PRODUCT 12 C- TERMINAL FRAGMENT | BETA BARREL, VIRAL PROTEIN
3gqk:A (HIS796) to (LYS854) CRYSTAL STRUCTURE OF THE BACTERIOPHAGE PHI29 GENE PRODUCT 12 C- TERMINAL FRAGMENT IN COMPLEX WITH ATP | BETA BARREL, VIRAL PROTEIN
2ddx:A (ALA34) to (ILE61) CRYSTAL STRUCTURE OF BETA-1,3-XYLANASE FROM VIBRIO SP. AX-4 | BETA-1, 3-XYLANASE, GLYCOSIDE HYDROLASE, TIM BARREL, HYDROLASE
2r5h:A (LEU43) to (GLY67) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 16 | CAPSID, PENTAMER, PROTEIN, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID PROTEIN, VIRION, VIRAL PROTEIN
2r5h:L (ARG41) to (SER66) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 16 | CAPSID, PENTAMER, PROTEIN, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID PROTEIN, VIRION, VIRAL PROTEIN
2r5h:O (ARG41) to (SER66) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 16 | CAPSID, PENTAMER, PROTEIN, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID PROTEIN, VIRION, VIRAL PROTEIN
2r5i:C (LEU42) to (ALA67) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 18 | HPV18, PENTAMER, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID, CAPSID PROTEIN, VIRION, VIRAL PROTEIN
2r5i:F (LEU42) to (ALA67) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 18 | HPV18, PENTAMER, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID, CAPSID PROTEIN, VIRION, VIRAL PROTEIN
2r5i:I (LEU42) to (ALA67) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 18 | HPV18, PENTAMER, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID, CAPSID PROTEIN, VIRION, VIRAL PROTEIN
2r5i:M (LEU42) to (ALA67) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 18 | HPV18, PENTAMER, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID, CAPSID PROTEIN, VIRION, VIRAL PROTEIN
2r5k:B (SER39) to (GLY64) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 11 | HPV11, CAPSID, PENTAMER, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID PROTEIN, LATE PROTEIN, VIRION, VIRAL PROTEIN
2r5k:D (SER39) to (GLY64) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 11 | HPV11, CAPSID, PENTAMER, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID PROTEIN, LATE PROTEIN, VIRION, VIRAL PROTEIN
3tgt:A (GLY263) to (LEU288) CRYSTAL STRUCTURE OF UNLIGANDED HIV-1 CLADE A/E STRAIN 93TH057 GP120 CORE | HIV-1 GP120, UNLIGANDED STRUCTURE, CLADE A/E 93TH057, VIRAL PROTEIN
1q31:A (SER153) to (THR180) CRYSTAL STRUCTURE OF THE TOBACCO ETCH VIRUS PROTEASE C151A MUTANT | 3C-TYPE PROTEASE, TEV, TWO-DOMAIN, ANTIPARALLEL, BETA-BARREL, TRYPSIN-LIKE, C151A, VIRAL PROTEIN, HYDROLASE
1q31:B (SER153) to (THR180) CRYSTAL STRUCTURE OF THE TOBACCO ETCH VIRUS PROTEASE C151A MUTANT | 3C-TYPE PROTEASE, TEV, TWO-DOMAIN, ANTIPARALLEL, BETA-BARREL, TRYPSIN-LIKE, C151A, VIRAL PROTEIN, HYDROLASE
3th2:H (THR206) to (THR229) MG2+ IS REQUIRED FOR OPTIMAL FOLDING OF THE GAMMA-CARBOXYGLUTAMIC ACID (GLA) DOMAINS OF VITAMIN K-DEPENDENT CLOTTING FACTORS AT PHYSIOLOGICAL CA2+ | HYDROLASE, BLOOD CLOTTING, SERINE PROTEASE, BLOOD COAGULATION, SOLUBLE TISSUE FACTOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4j9g:E (GLU86) to (PRO112) CRYSTAL STRUCTURE OF THE ABL-SH3 DOMAIN COMPLEXED WITH THE DESIGNED HIGH-AFFINITY PEPTIDE LIGAND P7 AT PH7 | BETA SHANDWICH, SH3 DOMAIN, KINASE, POLY PROLINE RICH MOTIFS, TRANSFERASE, TRANSFERASE-UNKNOWN FUNCTION COMPLEX
4j9h:B (ASN64) to (THR83) CRYSTAL STRUCTURE OF THE ABL-SH3 DOMAIN COMPLEXED WITH THE DESIGNED HIGH-AFFINITY PEPTIDE LIGAND P7 AT PH 8 | BETA SHANDWICH, SH3 DOMAIN, KINASE, POLY PROLINE RICH MOTIFS, TRANSFERASE, TRANSFERASE-UNKNOWN FUNCTION COMPLEX
3gtm:B (GLY902) to (LEU941) CO-COMPLEX OF BACKTRACKED RNA POLYMERASE II WITH TFIIS | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA- DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, TRANSCRIPTION REGULATION, TRANSFERASE/DNA-RNA HYBRID COMPLEX
3gtp:B (GLY902) to (LEU941) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 24MER RNA | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA- DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, TRANSFERASE/DNA-RNA HYBRID COMPLEX
3gtp:B (THR944) to (PRO974) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 24MER RNA | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA- DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, TRANSFERASE/DNA-RNA HYBRID COMPLEX
1q7x:A (ILE10) to (LEU68) SOLUTION STRUCTURE OF THE ALTERNATIVELY SPLICED PDZ2 DOMAIN (PDZ2B) OF PTP-BAS (HPTP1E) | PHOSPHATASE, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, STRUCTURAL GENOMICS, HYDROLASE
1ecz:B (LYS94) to (GLU133) PROTEASE INHIBITOR ECOTIN | BETA-SHEET STRUCTURE, SERINE PROTEASE INHIBITOR, PERIPLASMIC
3tl8:D (LYS411) to (VAL432) THE AVRPTOB-BAK1 COMPLEX REVEALS TWO STRUCTURALLY SIMILAR KINASEINTERACTING DOMAINS IN A SINGLE TYPE III EFFECTOR | PLANT IMMUNITY, PSEUDOMONAS SYRINGAE, SOLANUM LYCOPERSICUM, PAMP- TRIGGERED IMMUNITY, BACTERIAL PATHOGENESIS, TRANSFERASE-LIGASE COMPLEX
4jdt:G (GLY263) to (LEU288) CRYSTAL STRUCTURE OF CHIMERIC GERM-LINE PRECURSOR OF NIH45-46 FAB IN COMPLEX WITH GP120 OF 93TH057 HIV-1 | IG FOLD, ANTI HIV, ANTIBODY, IMMUNE SYSTEM COMPLEX, VIRAL PROTEIN- IMMUNE SYSTEM COMPLEX
2r9c:A (SER246) to (ARG295) CALPAIN 1 PROTEOLYTIC CORE INACTIVATED BY ZLAK-3001, AN ALPHA- KETOAMIDE | PROTEASE, PEPTIDASE, INHIBITOR, ALPHA-KETOAMIDE, HYDROLASE, MEMBRANE, THIOL PROTEASE
2r9f:A (SER246) to (ARG295) CALPAIN 1 PROTEOLYTIC CORE INACTIVATED BY ZLAK-3002, AN ALPHA- KETOAMIDE | PROTEASE, PEPTIDASE, INHIBITOR, ALPHA-KETOAMIDE, HYDROLASE, MEMBRANE, THIOL PROTEASE
1qcs:A (ASN20) to (PHE47) N-TERMINAL DOMAIN OF N-ETHYLMALEIMIDE SENSITIVE FACTOR (NSF) | DOUBLE-PSI BETA BARREL ALPHA BETA ROLL, FUSION PROTEIN
1qdn:A (ASN20) to (PHE47) AMINO TERMINAL DOMAIN OF THE N-ETHYLMALEIMIDE SENSITIVE FUSION PROTEIN (NSF) | DOUBLE-PSI BETA BARREL ALPHA/BETA BARREL, VESICULAR-FUSION PROTEIN
1qdn:C (ASN20) to (PHE47) AMINO TERMINAL DOMAIN OF THE N-ETHYLMALEIMIDE SENSITIVE FUSION PROTEIN (NSF) | DOUBLE-PSI BETA BARREL ALPHA/BETA BARREL, VESICULAR-FUSION PROTEIN
1ekv:A (ARG306) to (PRO333) HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL): THREE DIMENSIONAL STRUCTURE OF ENZYME INACTIVATED BY TRIS BOUND TO THE PYRIDOXAL-5'-PHOSPHATE ON ONE END AND ACTIVE SITE LYS202 NZ ON THE OTHER. | FOLD TYPE IV, TRANSFERASE
1ekv:B (ARG306) to (PRO333) HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL): THREE DIMENSIONAL STRUCTURE OF ENZYME INACTIVATED BY TRIS BOUND TO THE PYRIDOXAL-5'-PHOSPHATE ON ONE END AND ACTIVE SITE LYS202 NZ ON THE OTHER. | FOLD TYPE IV, TRANSFERASE
1ela:A (GLY205) to (THR239) ANALOGOUS INHIBITORS OF ELASTASE DO NOT ALWAYS BIND ANALOGOUSLY | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, SERINE PROTEINASE
1eld:E (GLY205) to (THR239) STRUCTURAL ANALYSIS OF THE ACTIVE SITE OF PORCINE PANCREATIC ELASTASE BASED ON THE X-RAY CRYSTAL STRUCTURES OF COMPLEXES WITH TRIFLUOROACETYL-DIPEPTIDE-ANILIDE INHIBITORS | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, SERINE PROTEINASE
1ele:E (GLY205) to (THR239) STRUCTURAL ANALYSIS OF THE ACTIVE SITE OF PORCINE PANCREATIC ELASTASE BASED ON THE X-RAY CRYSTAL STRUCTURES OF COMPLEXES WITH TRIFLUOROACETYL-DIPEPTIDE-ANILIDE INHIBITORS | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, SERINE PROTEINASE
2rg3:A (SER197) to (ALA229) COVALENT COMPLEX STRUCTURE OF ELASTASE | ELASTASE, COMPLEX, COVALENT, DISEASE MUTATION, GLYCOPROTEIN, HYDROLASE, PROTEASE, SERINE PROTEASE, ZYMOGEN
1enf:A (PHE25) to (ALA58) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN H DETERMINED TO 1.69 A RESOLUTION | BETA-BARREL, BETA-GRASP, TOXIN
2e00:A (VAL269) to (LEU300) CRYSTAL STRUCTURE OF N392L MUTANT OF YEAST BLEOMYCIN HYDROLASE | BLEOMYCIN HYDROLASE, THIOL PROTEASE, C1 PROTEASE, HYDROLASE
2e03:A (VAL269) to (LEU300) CRYSTAL STRUCTURE OF NQ67E MUTANT OF YEAST BLEOMYCIN HYDROLASE | BLEOMYCIN HYDROLASE, THIOL PROTEASE, C1 PROTEAS, HYDROLASE
1ep5:B (GLY227) to (SER254) CRYSTAL STRUCTURE OF THE CONSERVED CORE DOMAIN OF VENEZUALAN EQUINE ENCEPHALITIS CAPSID PROTEIN | BETA BARREL, HYDROLASE
1ep6:C (GLY227) to (SER254) CRYSTAL STRUCTURE OF THE CONSERVED CORE DOMAIN OF VENEZUALAN EQUINE ENCEPHALITIS CAPSID PROTEIN | BETA BARREL, HYDROLASE
4jkp:G (GLY263) to (LEU288) RESTRICTING HIV-1 PATHWAYS FOR ESCAPE USING RATIONALLY-DESIGNED ANTI- HIV-1 ANTIBODIES | IGG, ANTIBODY, GP120, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
1esa:A (GLY205) to (THR239) DIRECT STRUCTURE OBSERVATION OF AN ACYL-ENZYME INTERMEDIATE IN THE HYDROLYSIS OF AN ESTER SUBSTRATE BY ELASTASE | HYDROLASE(SERINE PROTEINASE)
1eu4:A (ASN20) to (PHE52) CRYSTAL STRUCTURE OF THE SUPERANTIGEN SPE-H (ZINC BOUND) FROM STREPTOCOCCUS PYOGENES | BETA GRASP, OB FOLD, SUPERANTIGEN FOLD, IMMUNE SYSTEM
2rov:A (TYR47) to (LEU96) THE SPLIT PH DOMAIN OF ROCK II | PROTEIN, ATP-BINDING, COILED COIL, CYTOPLASM, KINASE, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PHORBOL-ESTER BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, ZINC, ZINC-FINGER
4jmy:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3/NS4A PROTEASE COMPLEXED WITH DDIVPC PEPTIDE | HEPATITIS C VIRUS, SERINE PROTEASE, DDIVPC, HYDROLASE-PROTEIN BINDING COMPLEX
4jmy:B (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3/NS4A PROTEASE COMPLEXED WITH DDIVPC PEPTIDE | HEPATITIS C VIRUS, SERINE PROTEASE, DDIVPC, HYDROLASE-PROTEIN BINDING COMPLEX
3h32:B (ILE252) to (GLU291) CRYSTAL STRUCTURE OF D-DIMER FROM HUMAN FIBRIN COMPLEXED WITH GLY-HIS- ARG-PRO-TYR-AMIDE | FIBRINOGEN, FIBRIN CLOTS, BLOOD CLOTTING, AMYLOID, AMYLOIDOSIS, BLOOD COAGULATION, DISEASE MUTATION, DISULFIDE BOND, GLYCOPROTEIN, ISOPEPTIDE BOND, PHOSPHOPROTEIN, SECRETED, PYRROLIDONE CARBOXYLIC ACID, SULFATION, CDNA FLJ75335, TRANSCRIPT VARIANT GAMMA-A, MRNA, ISOFORM CRA_M
4jo3:I (THR107) to (PRO147) CRYSTAL STRUCTURE OF RABBIT MAB R20 FAB IN COMPLEX WITH V3 C-TERMINUS OF HIV-1 CONSENSUS B GP120 | IG, ANTIBODY, IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX
2sfa:A (GLY148) to (GLN177) SERINE PROTEINASE FROM STREPTOMYCES FRADIAE ATCC 14544 | HYDROLASE, SERINE PROTEASE
2sgd:E (GLY196) to (GLN229) ASP 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7 | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
4joo:A (THR107) to (GLU127) SPIROCYCLIC BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1 (BACE1) INHIBITORS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4jp9:A (THR107) to (GLU127) SPIROCYCLIC BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1 (BACE1) INHIBITORS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4jpc:A (THR107) to (GLU127) SPIROCYCLIC BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1 (BACE1) INHIBITORS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3h3v:C (GLY902) to (LEU941) YEAST RNAP II CONTAINING POLY(A)-SIGNAL SEQUENCE IN THE ACTIVE SITE | TRANSFERASE/DNA/RNA, DNA-BINDING, PHOSPHORYLATION, RNA POLYMERASE II, METAL-BINDING, NUCLEAR PROTEIN, TRANSCRIPTION BUBBLE, ELONGATION COMPLEX, TRANSFERASE, TRANSCRIPTION, POLYADENYLATION, TERMINATION, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, ZINC-FINGER, DNA DAMAGE, DNA REPAIR, MRNA PROCESSING, TRANSFERASE-DNA-RNA COMPLEX
4jpe:A (THR107) to (GLU127) SPIROCYCLIC BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1 (BACE1) INHIBITORS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1eys:H (THR155) to (GLU185) CRYSTAL STRUCTURE OF PHOTOSYNTHETIC REACTION CENTER FROM A THERMOPHILIC BACTERIUM, THERMOCHROMATIUM TEPIDUM | MEMBRANE PROTEIN COMPLEX, ELECTRON TRANSPORT
3h43:C (LEU117) to (PRO149) N-TERMINAL DOMAIN OF THE PROTEASOME-ACTIVATING NUCLEOTIDASE OF METHANOCALDOCOCCUS JANNASCHII | PROTEASOME, REGULATORY PARTICLE, NUCLEOSIDASE, ATP-BINDING, CYTOPLASM, NUCLEOTIDE-BINDING, HYDROLASE
3h43:D (LEU117) to (PRO149) N-TERMINAL DOMAIN OF THE PROTEASOME-ACTIVATING NUCLEOTIDASE OF METHANOCALDOCOCCUS JANNASCHII | PROTEASOME, REGULATORY PARTICLE, NUCLEOSIDASE, ATP-BINDING, CYTOPLASM, NUCLEOTIDE-BINDING, HYDROLASE
3h43:F (LEU117) to (PRO149) N-TERMINAL DOMAIN OF THE PROTEASOME-ACTIVATING NUCLEOTIDASE OF METHANOCALDOCOCCUS JANNASCHII | PROTEASOME, REGULATORY PARTICLE, NUCLEOSIDASE, ATP-BINDING, CYTOPLASM, NUCLEOTIDE-BINDING, HYDROLASE
3h43:G (PRO114) to (PRO149) N-TERMINAL DOMAIN OF THE PROTEASOME-ACTIVATING NUCLEOTIDASE OF METHANOCALDOCOCCUS JANNASCHII | PROTEASOME, REGULATORY PARTICLE, NUCLEOSIDASE, ATP-BINDING, CYTOPLASM, NUCLEOTIDE-BINDING, HYDROLASE
3two:A (VAL85) to (THR115) THE CRYSTAL STRUCTURE OF CAD FROM HELICOBACTER PYLORI COMPLEXED WITH NADP(H) | HELICOBACTER PYLORI, CINNAMYL-ALCOHOL DEHYDROGENASE, NADP(H), OXIDOREDUCTASE
1qp3:A (LYS7) to (GLU41) SOLUTION STRUCTURE OF PHOTOSYSTEM I ACCESSORY PROTEIN E FROM THE CYANOBACTERIUM NOSTOC SP. STRAIN PCC 8009 | MAINLY BETA, ROLL, PLECKSTRIN TOPOLOGY, SH3-LIKE, ELECTRON TRANSPORT
4yjf:B (GLY277) to (TYR309) CRYSTAL STRUCTURE OF DAAO(Y228L/R283G) VARIANT (S-METHYLBENZYLAMINE BINDING FORM) | AMINE OXIDASE, VARIANT OF D-AMINO ACID OXIDASE, S-METHYLBENZYLAMINE BINDING FORM, OXIDOREDUCTASE
2e5p:A (VAL16) to (GLN43) SOLUTION STRUCTURE OF THE TUDOR DOMAIN OF PHD FINGER PROTEIN 1 (PHF1 PROTEIN) | NMR, TUDOR DOMAIN, PHD FINGER PROTEIN 1, PHF1 PROTEIN, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSCRIPTION
4yjd:B (GLY277) to (TYR309) CRYSTAL STRUCTURE OF DAAO(Y228L/R283G) VARIANT (APO FORM) | AMINE OXIDASE, VARIANT OF D-AMINO ACID OXIDASE, APO FORM, OXIDOREDUCTASE
1f3t:A (VAL335) to (VAL367) CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI ORNITHINE DECARBOXYLASE (ODC) COMPLEXED WITH PUTRESCINE, ODC'S REACTION PRODUCT. | BETA-ALPHA-BARREL, MODIFIED GREEK KEY BETA-SHEET, LYASE
1f3t:C (VAL335) to (VAL367) CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI ORNITHINE DECARBOXYLASE (ODC) COMPLEXED WITH PUTRESCINE, ODC'S REACTION PRODUCT. | BETA-ALPHA-BARREL, MODIFIED GREEK KEY BETA-SHEET, LYASE
1f3t:D (ARG337) to (VAL367) CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI ORNITHINE DECARBOXYLASE (ODC) COMPLEXED WITH PUTRESCINE, ODC'S REACTION PRODUCT. | BETA-ALPHA-BARREL, MODIFIED GREEK KEY BETA-SHEET, LYASE
1qu4:B (VAL335) to (VAL367) CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI ORNITHINE DECARBOXYLASE | POLYAMINE METABOLISM, PYRIDOXAL 5'-PHOSPHATE, ALPHA-BETA BARREL, LYASE
1qu4:C (VAL335) to (VAL367) CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI ORNITHINE DECARBOXYLASE | POLYAMINE METABOLISM, PYRIDOXAL 5'-PHOSPHATE, ALPHA-BETA BARREL, LYASE
3u28:C (ALA65) to (ASP96) CRYSTAL STRUCTURE OF A CBF5-NOP10-GAR1 COMPLEX FROM SACCHAROMYCES CEREVISIAE | PSEUDOURIDINE SYNTHASE, PSEUDOURIDYLATION, H/ACA RNA, NUCLEOLUS, ISOMERASE-PROTEIN BINDING COMPLEX
1f77:A (PRO24) to (ALA58) STAPHYLOCOCCAL ENTEROTOXIN H DETERMINED TO 2.4 A RESOLUTION | BETA-BARREL, BETA-GRASP, TOXIN
1f77:B (PHE25) to (ALA58) STAPHYLOCOCCAL ENTEROTOXIN H DETERMINED TO 2.4 A RESOLUTION | BETA-BARREL, BETA-GRASP, TOXIN
1f92:A (GLY197) to (THR229) UROKINASE PLASMINOGEN ACTIVATOR B CHAIN-UKI-1D COMPLEX | UROKINASE, INHIBITOR, SERINE PROTEASE, HUMAN, HYDROLASE
4jwx:A (THR77) to (GLY98) GLUN2A LIGAND-BINDING CORE IN COMPLEX WITH PROPYL-NHP5G | BILOBED STRUCTURE, UNKNOWN FUNCTION
3he1:B (TYR6) to (THR71) SECRETED PROTEIN HCP3 FROM PSEUDOMONAS AERUGINOSA. | STRUCTURAL GENOMICS, APC22128, HCP3, HCPC, SECRETION, VIRULENCE, PSI- 2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, SECRETED, UNKNOWN FUNCTION
3he1:C (THR3) to (THR71) SECRETED PROTEIN HCP3 FROM PSEUDOMONAS AERUGINOSA. | STRUCTURAL GENOMICS, APC22128, HCP3, HCPC, SECRETION, VIRULENCE, PSI- 2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, SECRETED, UNKNOWN FUNCTION
3he1:F (TYR6) to (THR71) SECRETED PROTEIN HCP3 FROM PSEUDOMONAS AERUGINOSA. | STRUCTURAL GENOMICS, APC22128, HCP3, HCPC, SECRETION, VIRULENCE, PSI- 2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, SECRETED, UNKNOWN FUNCTION
4jzz:A (GLY263) to (ASN289) CRYSTAL STRUCTURE OF CD4-MIMETIC MINIPROTEIN M48U1 IN COMPLEX WITH HIV-1 YU2 GP120 IN C2221 SPACE GROUP | HIV-1 ATTACHMENT PROTEIN GP120, HIV-1 ENVELOPE, VIRAL PROTEIN- INHIBITOR COMPLEX
4k1s:B (ASP48) to (GLU84) GLY-SER-SPLB PROTEASE FROM STAPHYLOCOCCUS AUREUS AT 1.96 A RESOLUTION | CHYMOTRYPSIN-LIKE FOLD, SERINE PROTEASE, EXTRACELLULAR, HYDROLASE
2v3m:B (SER168) to (PRO198) STRUCTURE OF THE GAR1 DOMAIN OF NAF1 | RIBOSOMAL PROTEIN, NAF1, GAR1, SNORNP, PHOSPHORYLATION, HYPOTHETICAL PROTEIN
2v3m:C (GLY167) to (PRO198) STRUCTURE OF THE GAR1 DOMAIN OF NAF1 | RIBOSOMAL PROTEIN, NAF1, GAR1, SNORNP, PHOSPHORYLATION, HYPOTHETICAL PROTEIN
2v3m:D (SER168) to (PRO198) STRUCTURE OF THE GAR1 DOMAIN OF NAF1 | RIBOSOMAL PROTEIN, NAF1, GAR1, SNORNP, PHOSPHORYLATION, HYPOTHETICAL PROTEIN
2v3m:E (GLY167) to (PRO198) STRUCTURE OF THE GAR1 DOMAIN OF NAF1 | RIBOSOMAL PROTEIN, NAF1, GAR1, SNORNP, PHOSPHORYLATION, HYPOTHETICAL PROTEIN
3ue4:A (ASN358) to (VAL379) STRUCTURAL AND SPECTROSCOPIC ANALYSIS OF THE KINASE INHIBITOR BOSUTINIB BINDING TO THE ABL TYROSINE KINASE DOMAIN | PROTEIN KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4k3y:D (GLY96) to (VAL134) CRYSTAL STRUCTURE OF A SUBTYPE N11 NEURAMINIDASE-LIKE PROTEIN OF A/FLAT-FACED BAT/PERU/033/2010 (H18N11) | INFLUENZA VIRUS, NEURAMINIDASE-LIKE, N11, BETA PROPELLER, VIRAL PROTEIN
1fnv:A (PRO29) to (GLU61) STRUCTURE OF STREPTOCOCCAL PYROGENIC EXOTOXIN A | EXOTOXIN A, SUPERANTIGEN
1fnv:C (PRO629) to (GLU661) STRUCTURE OF STREPTOCOCCAL PYROGENIC EXOTOXIN A | EXOTOXIN A, SUPERANTIGEN
1fnw:C (PRO629) to (GLU661) CRYSTAL STRUCTURE OF STREPTOCOCCAL PYROGENIC EXOTOXIN A | EXOTOXIN A, SUPERANTIGEN
1fnw:H (PRO2129) to (GLU2161) CRYSTAL STRUCTURE OF STREPTOCOCCAL PYROGENIC EXOTOXIN A | EXOTOXIN A, SUPERANTIGEN
2ey4:C (ASP28) to (LYS56) CRYSTAL STRUCTURE OF A CBF5-NOP10-GAR1 COMPLEX | TRIMERIC COMPLEX, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, SOUTHEAST COLLABORATORY FOR STRUCTURAL GENOMICS, SECSG, ISOMERASE-BIOSYNTHETIC PROTEIN COMPLEX
2ey4:D (ASP28) to (LYS56) CRYSTAL STRUCTURE OF A CBF5-NOP10-GAR1 COMPLEX | TRIMERIC COMPLEX, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, SOUTHEAST COLLABORATORY FOR STRUCTURAL GENOMICS, SECSG, ISOMERASE-BIOSYNTHETIC PROTEIN COMPLEX
1frf:L (GLY314) to (TYR376) CRYSTAL STRUCTURE OF THE NI-FE HYDROGENASE FROM DESULFOVIBRIO FRUCTOSOVORANS | NI-FE HYDROGENASE, OXIDOREDUCTASE
4k8b:A (GLY140) to (VAL170) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE COMPLEXED WITH INHIBITOR | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4k8b:B (GLY140) to (VAL170) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE COMPLEXED WITH INHIBITOR | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1fuj:C (GLY196) to (THR229) PR3 (MYELOBLASTIN) | HYDROLASE, SERINE PROTEASE, GLYCOPROTEIN, ZYMOGEN, HYDROLASE (SERINE PROTEASE)
2f43:A (GLU51) to (VAL74) RAT LIVER F1-ATPASE | ATP SYNTHASE, F0F1-ATPASE, OXIDATIVE PHOSPHORYLATION, MITOCHONDRIA, HYDROLASE, VANADATE
1fxv:B (VAL118) to (ALA142) PENICILLIN ACYLASE MUTANT IMPAIRED IN CATALYSIS WITH PENICILLIN G IN THE ACTIVE SITE | NTN-HYDROLASE FOLD
1fxy:A (GLY197) to (THR229) COAGULATION FACTOR XA-TRYPSIN CHIMERA INHIBITED WITH D-PHE-PRO-ARG- CHLOROMETHYLKETONE | CHIMERA, PROTEASE, CHLOROMETHYLKETONE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1fy3:A (THR177) to (THR204) [G175Q]HBP, A MUTANT OF HUMAN HEPARIN BINDING PROTEIN (CAP37) | SERINE PROTEASE HOMOLOG, BPTI BINDING SITE, ANTIMICROBIAL PROTEIN
4yz0:B (GLY99) to (LYS121) C. BESCII FAMILY 3 PECTATE LYASE DOUBLE MUTANT K108A/E39Q IN COMPLEX WITH TRIGALACTURONIC ACID | PL3, PARALLEL BETA-HELIX, LYASE
4yz0:B (PHE123) to (ASP148) C. BESCII FAMILY 3 PECTATE LYASE DOUBLE MUTANT K108A/E39Q IN COMPLEX WITH TRIGALACTURONIC ACID | PL3, PARALLEL BETA-HELIX, LYASE
4yza:B (GLY99) to (LYS121) C. BESCII FAMILY 3 PECTATE LYASE DOUBLE MUTANT K108A/Q111A IN COMPLEX WITH TRIGALACTURONIC ACID | PL3, PARALLEL BETA-HELIX, LYASE
4yza:B (PHE123) to (ASP148) C. BESCII FAMILY 3 PECTATE LYASE DOUBLE MUTANT K108A/Q111A IN COMPLEX WITH TRIGALACTURONIC ACID | PL3, PARALLEL BETA-HELIX, LYASE
4z06:A (GLY99) to (LYS121) C. BESCII FAMILY 3 PECTATE LYASE DOUBLE MUTANT K108A/R133A IN COMPLEX WITH ALPHA-D-GALACTOPYRANURONIC ACID | PL3, PARALLEL BETA-HELIX, LYASE
4z06:A (PHE123) to (ASP148) C. BESCII FAMILY 3 PECTATE LYASE DOUBLE MUTANT K108A/R133A IN COMPLEX WITH ALPHA-D-GALACTOPYRANURONIC ACID | PL3, PARALLEL BETA-HELIX, LYASE
4z06:B (GLY99) to (LYS121) C. BESCII FAMILY 3 PECTATE LYASE DOUBLE MUTANT K108A/R133A IN COMPLEX WITH ALPHA-D-GALACTOPYRANURONIC ACID | PL3, PARALLEL BETA-HELIX, LYASE
4z06:B (PHE123) to (ASP148) C. BESCII FAMILY 3 PECTATE LYASE DOUBLE MUTANT K108A/R133A IN COMPLEX WITH ALPHA-D-GALACTOPYRANURONIC ACID | PL3, PARALLEL BETA-HELIX, LYASE
2f9o:A (GLY197) to (THR229) CRYSTAL STRUCTURE OF THE RECOMBINANT HUMAN ALPHA I TRYPTASE MUTANT D216G | SERINE PROTEINASE, TRYPSIN-LIKE, DIFUCOSYLATION, HYDROLASE
2f9o:C (GLY197) to (THR229) CRYSTAL STRUCTURE OF THE RECOMBINANT HUMAN ALPHA I TRYPTASE MUTANT D216G | SERINE PROTEINASE, TRYPSIN-LIKE, DIFUCOSYLATION, HYDROLASE
2f9v:A (GLY140) to (ILE170) HCV NS3 PROTEASE DOMAIN WITH NS4A PEPTIDE AND A KETOAMIDE INHIBITOR WITH P1 AND P2 CYCLOPROPYLALANNINES | HCV, HEPATITIS C PROTEASE, NS3 PROTEASE, KETOAMIDE INHIBITOR, VIRAL PROTEIN
1rtl:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3 PROTEASE DOMAIN: NS4A PEPTIDE COMPLEX WITH COVALENTLY BOUND PYRROLIDINE-5,5-TRANSLACTAM INHIBITOR | VIRAL PROTEIN, SERINE PROTEASE, NONSTRUCTURAL PROTEIN, COFACTOR PEPTIDE, HELICASE, INHIBITOR, TRANSLACTAM, VIRAL PROTEIN COMPLEX
1rtl:B (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3 PROTEASE DOMAIN: NS4A PEPTIDE COMPLEX WITH COVALENTLY BOUND PYRROLIDINE-5,5-TRANSLACTAM INHIBITOR | VIRAL PROTEIN, SERINE PROTEASE, NONSTRUCTURAL PROTEIN, COFACTOR PEPTIDE, HELICASE, INHIBITOR, TRANSLACTAM, VIRAL PROTEIN COMPLEX
2fd4:A (ARG449) to (ASP518) CRYSTAL STRUCTURE OF AVRPTOB (436-553) | PSEUDOMONAS, AVRPTOB, RING FINGER, U-BOX, UBIQUITIN LIGASE, LIGASE
2fdw:C (LEU370) to (LYS387) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH THE INHIBITOR (5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
3uou:A (GLY216) to (THR250) CRYSTAL STRUCTURE OF THE KUNITZ-TYPE PROTEASE INHIBITOR SHPI-1 LYS13LEU MUTANT IN COMPLEX WITH PANCREATIC ELASTASE | PROTEIN-PROTEIN INTERACTION, HYDROLASE (SERINE PROTEASE), KUNITZ-TYPE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3hov:B (GLY902) to (LEU941) COMPLETE RNA POLYMERASE II ELONGATION COMPLEX II | RNA POLYMERASE II, METAL-BINDING, TRANSCRIPTION BUBBLE, ELONGATION COMPLEX, TRANSCRIPTION, DNA-RNA MISMATCH, DNA- BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, MRNA PROCESSING, TRANSFERASE/DNA/RNA HYBRID COMPLEX, TRANSFERASE/DNA/RNA COMPLEX
4z3t:B (GLN87) to (GLU112) MENINGOCOCCAL FACTOR H BINDING PROTEIN MUTANT L130R/G133D | VIRULENCE FACTOR, LIPOPROTEIN, LIGAND FOR COMPLEMENT FACTOR H, PROTEIN BINDING
2vgc:C (ALA179) to (GLY211) GAMMA-CHYMOTRYPSIN D-PARA-CHLORO-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX | HYDROLASE, SERINE PROTEASE
3ure:B (GLY196) to (GLU229) REPACK MUTANT (T181I, W199L, Q210I) OF ALPHA-LYTIC PROTEASE | SERINE PROTEASE, HYDROLASE
1rzk:G (GLY263) to (ASN289) HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B | COMPLEX (HIV ENVELOPE PROTEIN-CD4-FAB); HIV-1 EXTERIOR ENVELOPE GP120 FROM LABORATORY-ADAPTED ISOLATE; HXBC2; SURFACE T-CELL GLYCOPROTEIN CD4; ANTIGEN-BINDING FRAGMENT OF HUMAN IMMUNOGLOBULIN 17B, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
2vhc:A (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 N234G MUTANT IN COMPLEX WITH AMPCPP AND MN | NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE, VIRUS DSRNA, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE
2vhc:B (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 N234G MUTANT IN COMPLEX WITH AMPCPP AND MN | NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE, VIRUS DSRNA, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE
2vhc:C (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 N234G MUTANT IN COMPLEX WITH AMPCPP AND MN | NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE, VIRUS DSRNA, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE
2vhj:A (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 S252A MUTANT IN COMPLEX WITH ADP | NON- HYDROLYSABLE ATP ANALOGUE, HYDROLASE, VIRUS DSRNA, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE
2vhj:B (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 S252A MUTANT IN COMPLEX WITH ADP | NON- HYDROLYSABLE ATP ANALOGUE, HYDROLASE, VIRUS DSRNA, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE
2vhj:C (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 S252A MUTANT IN COMPLEX WITH ADP | NON- HYDROLYSABLE ATP ANALOGUE, HYDROLASE, VIRUS DSRNA, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE
2vhq:A (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 S252A MUTANT IN COMPLEX WITH ATP AND MG | NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE, VIRUS DSRNA, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE
2vhq:B (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 S252A MUTANT IN COMPLEX WITH ATP AND MG | NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE, VIRUS DSRNA, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE
2vhq:C (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 S252A MUTANT IN COMPLEX WITH ATP AND MG | NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE, VIRUS DSRNA, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE
2vht:A (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 R279A MUTANT IN COMPLEX WITH ATP | NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE, VIRUS DSRNA, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE
2vhu:A (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 K241C MUTANT IN COMPLEX WITH ADP AND MGCL | VIRUS DSRNA, HYDROLASE, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE, NON-HYDROLYSABLE ATP ANALOGUE
2vhu:C (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 K241C MUTANT IN COMPLEX WITH ADP AND MGCL | VIRUS DSRNA, HYDROLASE, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE, NON-HYDROLYSABLE ATP ANALOGUE
2vid:B (ASP48) to (GLU84) SERINE PROTEASE SPLB FROM STAPHYLOCOCCUS AUREUS AT 1.8A RESOLUTION | PROTEASE, SERINE PROTEASE, STAPHYLOCOCCUS AUREUS, HYDROLASE
2vit:B (THR116) to (PRO156) INFLUENZA VIRUS HEMAGGLUTININ, MUTANT WITH THR 155 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY | COMPLEX (HEMAGGLUTININ/IMMMUNOGLOBULIN), GLYCOPROTEIN
1g9n:G (GLY263) to (ASN289) HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B | COMPLEX (HIV ENVELOPE PROTEIN-CD4-FAB), HIV-1 EXTERIOR ENVELOPE GP120 FROM CLINICAL PRIMARY ISOLATE, YU2, T-CELL SURFACE GLYCOPROTEIN CD4, ANTIGEN-BINDING FRAGMENT OF HUMAN IMMUNOGLOBULIN 17B, VIRAL PROTEIN- IMMUNE SYSTEM COMPLEX
3hqp:C (ASP122) to (SER154) CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA PYRUVATE KINASE (LMPYK) IN COMPLEX WITH ATP, OXALATE AND FRUCTOSE 2,6 BISPHOSPHATE | TIM BARREL, T-STATE ENZYME, ALLOSTERIC ENZYME, GLYCOLYSIS, KINASE, MAGNESIUM, METAL-BINDING, PYRUVATE, TRANSFERASE
3hqp:D (ASP122) to (SER154) CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA PYRUVATE KINASE (LMPYK) IN COMPLEX WITH ATP, OXALATE AND FRUCTOSE 2,6 BISPHOSPHATE | TIM BARREL, T-STATE ENZYME, ALLOSTERIC ENZYME, GLYCOLYSIS, KINASE, MAGNESIUM, METAL-BINDING, PYRUVATE, TRANSFERASE
3hqp:E (ASP122) to (SER154) CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA PYRUVATE KINASE (LMPYK) IN COMPLEX WITH ATP, OXALATE AND FRUCTOSE 2,6 BISPHOSPHATE | TIM BARREL, T-STATE ENZYME, ALLOSTERIC ENZYME, GLYCOLYSIS, KINASE, MAGNESIUM, METAL-BINDING, PYRUVATE, TRANSFERASE
3hqp:F (LYS123) to (GLN151) CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA PYRUVATE KINASE (LMPYK) IN COMPLEX WITH ATP, OXALATE AND FRUCTOSE 2,6 BISPHOSPHATE | TIM BARREL, T-STATE ENZYME, ALLOSTERIC ENZYME, GLYCOLYSIS, KINASE, MAGNESIUM, METAL-BINDING, PYRUVATE, TRANSFERASE
3hqp:O (ASP122) to (SER154) CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA PYRUVATE KINASE (LMPYK) IN COMPLEX WITH ATP, OXALATE AND FRUCTOSE 2,6 BISPHOSPHATE | TIM BARREL, T-STATE ENZYME, ALLOSTERIC ENZYME, GLYCOLYSIS, KINASE, MAGNESIUM, METAL-BINDING, PYRUVATE, TRANSFERASE
1gba:A (GLY196) to (GLU229) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA | ACTIVE-SITE MUTATION, HYDROLASE (SERINE PROTEINASE)
1gbb:A (GLY196) to (GLU229) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gbc:A (GLY196) to (GLU229) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gbd:A (GLY196) to (GLU229) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gbf:A (GLY196) to (GLU229) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gbh:A (GLY196) to (GLU229) ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID | ACTIVE-SITE MUTATION, SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1gd7:C (LEU62) to (VAL81) CRYSTAL STRUCTURE OF A BIFUNCTIONAL PROTEIN (CSAA) WITH EXPORT-RELATED CHAPERONE AND TRNA-BINDING ACTIVITIES. | OLIGONUCLEOTIDE-BINDING FOLD, FUNCTIONAL DIMER, HYDROPHOBIC CAVITY, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, RNA BINDING PROTEIN
2fm2:A (GLY140) to (ILE170) HCV NS3-4A PROTEASE DOMAIN COMPLEXED WITH A KETOAMIDE INHIBITOR, SCH446211 | HEPATITIS C VIRUS, HCV, NS3/4A PROTEASE, KETOAMIDE INHIBITOR, HYDROLASE
2fm2:C (GLY140) to (ILE170) HCV NS3-4A PROTEASE DOMAIN COMPLEXED WITH A KETOAMIDE INHIBITOR, SCH446211 | HEPATITIS C VIRUS, HCV, NS3/4A PROTEASE, KETOAMIDE INHIBITOR, HYDROLASE
4z91:B (GLU159) to (PRO201) ELIC COCRYSTALLIZED WITH ISOFLUORANE IN A DESENSITIZED STATE | ELIC, ISOFLURANE, ANESTHETICS, DESENSITIZED STATE, TRANSPORT PROTEIN
4z91:I (GLU159) to (PRO201) ELIC COCRYSTALLIZED WITH ISOFLUORANE IN A DESENSITIZED STATE | ELIC, ISOFLURANE, ANESTHETICS, DESENSITIZED STATE, TRANSPORT PROTEIN
1ggd:C (ALA179) to (GLY211) CRYSTAL STUCTURE OF GAMMA CHYMOTRYPSIN WITH N-ACETYL-LEUCIL- PHENYLALANINE ALDEHYDE BOUND AT THE ACTIVE SITE | CHYMOTRYPSIN, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3uyy:A (SER297) to (TYR324) CRYSTAL STRUCTURES OF BRANCHED-CHAIN AMINOTRANSFERASE FROM DEINOCOCCUS RADIODURANS COMPLEXES WITH ALPHA-KETOISOCAPROATE AND L-GLUTAMATE SUGGEST ITS RADIO-RESISTANCE FOR CATALYSIS | BCAT, AMINO-ACID BIOSYNTHESIS, AMINOTRANSFERASE, BRANCHED-CHAIN AMINO ACID BIOSYNTHESIS, PYRIDOXAL PHOSPHATE, TRANSFERASE
3uyy:B (SER297) to (PHE323) CRYSTAL STRUCTURES OF BRANCHED-CHAIN AMINOTRANSFERASE FROM DEINOCOCCUS RADIODURANS COMPLEXES WITH ALPHA-KETOISOCAPROATE AND L-GLUTAMATE SUGGEST ITS RADIO-RESISTANCE FOR CATALYSIS | BCAT, AMINO-ACID BIOSYNTHESIS, AMINOTRANSFERASE, BRANCHED-CHAIN AMINO ACID BIOSYNTHESIS, PYRIDOXAL PHOSPHATE, TRANSFERASE
2fpz:D (GLY197) to (THR229) HUMAN TRYPTASE WITH 2-AMINO BENZIMIDAZOLE | SERINE PROTEASE, DRUG DESIGN, HYDROLASE
3uzo:A (SER297) to (PHE323) CRYSTAL STRUCTURES OF BRANCHED-CHAIN AMINOTRANSFERASE FROM DEINOCOCCUS RADIODURANS COMPLEXES WITH ALPHA-KETOISOCAPROATE AND L-GLUTAMATE SUGGEST ITS RADIO-RESISTANCE FOR CATALYSIS | BCAT, AMINO-ACID BIOSYNTHESIS, AMINOTRANSFERASE, BRANCHED-CHAIN AMINO ACID BIOSYNTHESIS, PYRIDOXAL PHOSPHATE, TRANSFERASE, L-GLUTAMATE
2fs9:D (THR206) to (THR229) HUMAN BETA TRYPTASE II WITH INHIBITOR CRA-28427 | SERINE PROTEASE, SERINE PROTEINASE, 28427, HYDROLASE
1gi7:B (GLY197) to (THR229) A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE | THREE-CENTERED, VERY SHORT HYDROGEN BOND, OXYANION HOLE WATER, SHIFT OF PKA OF HIS57, STRUCTURE-BASED DRUG DESIGN, SPECIFICITY, UROKINASE, TRYPSIN, THROMBIN, ZN+2-MEDIATED INHIBITION, BLOOD CLOTTING, HYDROLASE
1gj7:B (GLY197) to (THR229) ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS | SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN, BLOOD CLOTTING, HYDROLASE
1gjd:B (GLY197) to (THR229) ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS | SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN, BLOOD CLOTTING, HYDROLASE
1gja:B (GLY197) to (THR229) ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS | SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN, BLOOD CLOTTING, HYDROLASE
2fv5:A (LEU348) to (ASN381) CRYSTAL STRUCTURE OF TACE IN COMPLEX WITH IK682 | TACE ADAM17 ZN-ENDOPEPTIDASE, HYDROLASE
2fv9:A (GLY349) to (ASN381) CRYSTAL STUCTURE OF TACE IN COMPLEX WITH JMV 390-1 | TACE ADAM33 ZN-ENDOPEPTIDASE, HYDROLASE
2fxr:C (GLY197) to (THR229) HUMAN BETA TRYPTASE II COMPLEXED WITH ACTIVATED KETONE INHIBITOR CRA-29382 | SERINE PROTEASE, ACTIVATED KETONE INHIBITOR, PYRROLIDINE, CRA-29382, HYDROLASE
1gm8:B (VAL118) to (ALA142) CRYSTAL STRUCTURES OF PENICILLIN ACYLASE ENZYME-SUBSTRATE COMPLEXES: STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM | ANTIBIOTIC RESISTANCE, HYDROLASE
2vmk:C (GLY66) to (THR118) CRYSTAL STRUCTURE OF E. COLI RNASE E APOPROTEIN - CATALYTIC DOMAIN | NUCLEASE, HYDROLASE, CYTOPLASM, RNA-BINDING, RNA TURNOVER, ENDONUCLEASE, RNA PROCESSING
2fyd:D (ASP254) to (SER297) CATALYTIC DOMAIN OF BOVINE BETA 1, 4-GALACTOSYLTRANSFERASE IN COMPLEX WITH ALPHA-LACTALBUMIN, GLUCOSE, MN, AND UDP-N- ACETYLGALACTOSAMINE | LACTOSE SYTHASE, CATALYTIC INTERMEDIATE, TRANSFERASE
1gmh:G (ALA179) to (GLY211) REFINED CRYSTAL STRUCTURE OF "AGED" AND "NON-AGED" ORGANOPHOSPHORYL CONJUGATES OF GAMMA-CHYMOTRYPSIN | HYDROLASE(SERINE PROTEINASE)
1sge:E (GLY196) to (GLN229) GLU 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5 | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1sgi:E (ARG206) to (THR229) CRYSTAL STRUCTURE OF THE ANTICOAGULANT SLOW FORM OF THROMBIN | THROMBIN, ALLOSTERY, HYDROLASE
1sgn:E (GLY196) to (GLN229) ASN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1sgr:E (GLY196) to (GLN229) LEU 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B | SERINE PROTEINASE, PROTEIN INHIBITOR, COMPLEX (SERINE PROTEASE/INHIBITOR) COMPLEX
1sgp:E (GLY196) to (GLN229) ALA 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B | SERINE PROTEINASE, PROTEIN INHIBITOR, COMPLEX (SERINE PROTEASE/INHIBITOR) COMPLEX
1sgq:E (GLY196) to (GLN229) GLY 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B | SERINE PROTEINASE, PROTEIN INHIBITOR, COMPLEX (SERINE PROTEASE/INHIBITOR) COMPLEX
1sgy:E (GLY196) to (GLN229) TYR 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5 | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1shm:A (SER30) to (ASN52) CONVERGENT SOLUTIONS TO VHH DOMAIN STABILIZATION FROM NATURAL AND IN VITRO EVOLUTION | HEAVY CHAIN VARIABLE DOMAIN, VHH DOMAIN, IMMUNOGLOBULIN, IMMUNE SYSTEM
1shm:B (SER30) to (ASN52) CONVERGENT SOLUTIONS TO VHH DOMAIN STABILIZATION FROM NATURAL AND IN VITRO EVOLUTION | HEAVY CHAIN VARIABLE DOMAIN, VHH DOMAIN, IMMUNOGLOBULIN, IMMUNE SYSTEM
2vpf:G (GLY65) to (CYS104) VASCULAR ENDOTHELIAL GROWTH FACTOR REFINED TO 1.93 ANGSTROMS RESOLUTION | GROWTH FACTOR, CYSTINE KNOT, ANGIOGENESIS, VASCULOGENESIS
2g2u:B (GLY141) to (ASP163) CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) COMPLEX | BETA-LACTAMASE, BETA-LACTAMASE INHIBITOR, PROTEIN-PROTEIN COMPLEX, BLIP, SHV-1, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1slh:B (THR3) to (GLY48) MYCOBACTERIUM TUBERCULOSIS DUTPASE COMPLEXED WITH MAGNESIUM AND DUDP | JELLY-ROLL, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, HYDROLASE
1sn8:B (GLY66) to (THR118) CRYSTAL STRUCTURE OF THE S1 DOMAIN OF RNASE E FROM E. COLI (PB DERIVATIVE) | OB-FOLD, RNA-BINDING, HYDROLASE
3i4m:B (GLY902) to (LEU941) 8-OXOGUANINE CONTAINING RNA POLYMERASE II ELONGATION COMPLEX D | RNA POLYMERASE II, METAL-BINDING, TRANSCRIPTION BUBBLE, ELONGATION COMPLEX, TRANSCRIPTION, 8-OXOGUANINE, OXIDATIVE DAMAGE, DNA DAMAGE, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, ZINC-FINGER, DNA REPAIR, MRNA PROCESSING, TRANSCRIPTION,TRANSFERASE-DNA-RNA HYBRID COMPLEX
2vu8:E (GLY197) to (TYR228) CRYSTAL STRUCTURE OF AN INSECT INHIBITOR WITH A FUNGAL TRYPSIN | HYDROLASE/INHIBITOR, CANONICAL INHIBITOR, INHIBITOR, SERINE PROTEASE, SPECIES SELECTIVITY, INSECT, ZYMOGEN, PROTEASE, SECRETED, HYDROLASE
2g8j:A (SER246) to (ARG295) CALPAIN 1 PROTEOLYTIC CORE IN COMPLEX WITH SNJ-1945, A ALPHA-KETOAMIDE-TYPE INHIBITOR. | PROTEASE, PEPTIDASE, INHIBITOR, ALPHA-KETOAMIDE, HYDROLASE
1sqo:A (GLY213) to (THR245) SUBSTITUTED 2-NAPHTHAMIDINE INHIBITORS OF UROKINASE | PLASMINOGEN ACTIVATION, HYDROLASE, SERINE PROTEASE, GLYCOPROTEIN, KRINGLE, EGF-LIKE DOMAIN
1gvm:A (ASN227) to (ASN252) CHOLINE BINDING DOMAIN OF THE MAJOR AUTOLYSIN (C-LYTA) FROM STREPTOCOCCUS PNEUMONIAE | CHOLINE-BINDING DOMAIN, CELL WALL ATTACHMENT
1gvm:A (GLY291) to (LYS318) CHOLINE BINDING DOMAIN OF THE MAJOR AUTOLYSIN (C-LYTA) FROM STREPTOCOCCUS PNEUMONIAE | CHOLINE-BINDING DOMAIN, CELL WALL ATTACHMENT
1gvm:B (LYS247) to (ASP272) CHOLINE BINDING DOMAIN OF THE MAJOR AUTOLYSIN (C-LYTA) FROM STREPTOCOCCUS PNEUMONIAE | CHOLINE-BINDING DOMAIN, CELL WALL ATTACHMENT
1gvm:C (ASN227) to (ASN252) CHOLINE BINDING DOMAIN OF THE MAJOR AUTOLYSIN (C-LYTA) FROM STREPTOCOCCUS PNEUMONIAE | CHOLINE-BINDING DOMAIN, CELL WALL ATTACHMENT
1gvm:C (GLY291) to (LYS318) CHOLINE BINDING DOMAIN OF THE MAJOR AUTOLYSIN (C-LYTA) FROM STREPTOCOCCUS PNEUMONIAE | CHOLINE-BINDING DOMAIN, CELL WALL ATTACHMENT
1gvm:D (GLY291) to (LYS318) CHOLINE BINDING DOMAIN OF THE MAJOR AUTOLYSIN (C-LYTA) FROM STREPTOCOCCUS PNEUMONIAE | CHOLINE-BINDING DOMAIN, CELL WALL ATTACHMENT
1gvm:E (GLY291) to (LYS318) CHOLINE BINDING DOMAIN OF THE MAJOR AUTOLYSIN (C-LYTA) FROM STREPTOCOCCUS PNEUMONIAE | CHOLINE-BINDING DOMAIN, CELL WALL ATTACHMENT
1gvm:F (GLY291) to (LYS318) CHOLINE BINDING DOMAIN OF THE MAJOR AUTOLYSIN (C-LYTA) FROM STREPTOCOCCUS PNEUMONIAE | CHOLINE-BINDING DOMAIN, CELL WALL ATTACHMENT
4zj4:A (VAL65) to (LYS107) THE CRYSTAL STRUCTURE OF HUMAN PLASMA KALLIKREIN IN COMPLEX WITH ITS PEPTIDE INHIBITOR PKALIN-1 | PEPTIDE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR
4zj5:A (VAL65) to (LYS107) THE CRYSTAL STRUCTURE OF HUMAN PLASMA KALLIKREIN IN COMPLEX WITH ITS PEPTIDE INHIBITOR PKALIN-2 | PEPTIDE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2vyu:A (LYS32) to (GLY79) CRYSTAL STRUCTURE OF CHOLINE BINDING PROTEIN F FROM STREPTOCOCCUS PNEUMONIAE IN THE PRESENCE OF A PEPTIDOGLYCAN ANALOGUE (TETRASACCHARIDE-PENTAPEPTIDE) | CHOLINE-BINDING PROTEIN, CBPF, PEPTIDOGLYCAN, CHOLINE-BINDING-PROTEIN, LIPID-BINDING PROTEIN
3veq:B (GLY194) to (THR222) A BINARY COMPLEX BETWWEN BOVINE PANCREATIC TRYPSIN AND A ENGINEERED MUTANT TRYPSIN INHIBITOR | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vgc:C (ALA179) to (GLY211) GAMMA-CHYMOTRYPSIN L-NAPHTHYL-1-ACETAMIDO BORONIC ACID ACID INHIBITOR COMPLEX | HYDROLASE, SERINE PROTEASE
4zkr:U (GLY197) to (THR229) THE CRYSTAL STRUCTURE OF UPAIN-1-W3A IN COMPLEX WITH UPA AT PH9.0 | PEPTIDES INHIBITOR, UPA, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2gix:D (ASN55) to (LEU217) CYTOPLASMIC DOMAIN STRUCTURE OF KIR2.1 CONTAINING ANDERSEN'S MUTATION R218Q AND RESCUE MUTATION T309K | CYTOPLASMIC DOMAINS OF KIR2.1, ANDERSEN'S MUTATION, METAL TRANSPORT
2gkv:E (GLY196) to (GLN229) CRYSTAL STRUCTURE OF THE SGPB:P14'-ALA32 OMTKY3-DEL(1-5) COMPLEX | BETA-BARRELS, CATALYTIC TRIAD, SUBSTRATE-BINDING REGION, REACTIVE-SITE LOOP, ALPHA-HELIX, BETA-SHEET, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1t7c:C (ALA179) to (GLY211) CRYSTAL STRUCTURE OF THE P1 GLU BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX | CHYMOTRYPSIN; SERINE PROTEINASE; BOVINE PANCREATIC TRYPSIN INHIBITOR; BPTI; PROTEIN-PROTEIN INTERACTION; NON-COGNATE BINDING; S1 POCKET; PRIMARY SPECIFICITY; CRYSTAL STRUCTURE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1t8l:C (ALA179) to (GLY211) CRYSTAL STRUCTURE OF THE P1 MET BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX | CHYMOTRYPSIN; SERINE PROTEINASE; BOVINE PANCREATIC TRYPSIN INHIBITOR; BPTI; PROTEIN-PROTEIN INTERACTION; NON-COGNATE BINDING; S1 POCKET; PRIMARY SPECIFICITY; CRYSTAL STRUCTURE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1t8m:C (ALA179) to (GLY211) CRYSTAL STRUCTURE OF THE P1 HIS BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX | CHYMOTRYPSIN, SERINE PROTEINASE, BOVINE PANCREATIC TRYPSIN INHIBITOR, BPTI, PROTEIN-PROTEIN INTERACTION, NON-COGNATE BINDING; S1 POCKET, PRIMARY SPECIFICITY, CRYSTAL STRUCTURE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1t8o:A (ALA179) to (GLY211) CRYSTAL STRUCTURE OF THE P1 TRP BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX | CHYMOTRYPSIN, SERINE PROTEINASE, BOVINE PANCREATIC TRYPSIN INHIBITOR, BPTI, PROTEIN-PROTEIN INTERACTION, NON-COGNATE BINDING, S1 POCKET, PRIMARY SPECIFICITY, CRYSTAL STRUCTURE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1t8o:C (ALA179) to (GLY211) CRYSTAL STRUCTURE OF THE P1 TRP BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX | CHYMOTRYPSIN, SERINE PROTEINASE, BOVINE PANCREATIC TRYPSIN INHIBITOR, BPTI, PROTEIN-PROTEIN INTERACTION, NON-COGNATE BINDING, S1 POCKET, PRIMARY SPECIFICITY, CRYSTAL STRUCTURE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
4laj:J (GLY263) to (LEU288) CRYSTAL STRUCTURE OF HIV-1 YU2 ENVELOPE GP120 GLYCOPROTEIN IN COMPLEX WITH CD4-MIMETIC MINIPROTEIN, M48U1, AND LLAMA SINGLE-DOMAIN, BROADLY NEUTRALIZING, CO-RECEPTOR BINDING SITE ANTIBODY, JM4 | CD4-INDUCED ANTIBODY, HIV-1 NEUTRALIZING ANTIBODY, HIV-1 GP120 REACTIVE, VIRAL PROTEIN-INHIBITOR COMPLEX
2w5e:A (GLY552) to (VAL577) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF HUMAN PATHOGENIC ASTROVIRUS SERINE PROTEASE AT 2.0 ANGSTROM RESOLUTION | COILED COIL, TRANSMEMBRANE, THIOL PROTEASE, RNA REPLICATION, RIBOSOMAL FRAMESHIFTING, SERINE PROTEASE, CATALYTIC TRIAD, PROTEASE, MEMBRANE, HYDROLASE, ANTIVIRAL, ASTROVIRUS
2w5e:B (GLY552) to (VAL577) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF HUMAN PATHOGENIC ASTROVIRUS SERINE PROTEASE AT 2.0 ANGSTROM RESOLUTION | COILED COIL, TRANSMEMBRANE, THIOL PROTEASE, RNA REPLICATION, RIBOSOMAL FRAMESHIFTING, SERINE PROTEASE, CATALYTIC TRIAD, PROTEASE, MEMBRANE, HYDROLASE, ANTIVIRAL, ASTROVIRUS
2w5e:C (GLY552) to (VAL577) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF HUMAN PATHOGENIC ASTROVIRUS SERINE PROTEASE AT 2.0 ANGSTROM RESOLUTION | COILED COIL, TRANSMEMBRANE, THIOL PROTEASE, RNA REPLICATION, RIBOSOMAL FRAMESHIFTING, SERINE PROTEASE, CATALYTIC TRIAD, PROTEASE, MEMBRANE, HYDROLASE, ANTIVIRAL, ASTROVIRUS
2w5e:D (GLY552) to (VAL577) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF HUMAN PATHOGENIC ASTROVIRUS SERINE PROTEASE AT 2.0 ANGSTROM RESOLUTION | COILED COIL, TRANSMEMBRANE, THIOL PROTEASE, RNA REPLICATION, RIBOSOMAL FRAMESHIFTING, SERINE PROTEASE, CATALYTIC TRIAD, PROTEASE, MEMBRANE, HYDROLASE, ANTIVIRAL, ASTROVIRUS
2w5e:E (GLY552) to (VAL577) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF HUMAN PATHOGENIC ASTROVIRUS SERINE PROTEASE AT 2.0 ANGSTROM RESOLUTION | COILED COIL, TRANSMEMBRANE, THIOL PROTEASE, RNA REPLICATION, RIBOSOMAL FRAMESHIFTING, SERINE PROTEASE, CATALYTIC TRIAD, PROTEASE, MEMBRANE, HYDROLASE, ANTIVIRAL, ASTROVIRUS
2w5e:F (GLY552) to (VAL577) STRUCTURAL AND BIOCHEMICAL ANALYSIS OF HUMAN PATHOGENIC ASTROVIRUS SERINE PROTEASE AT 2.0 ANGSTROM RESOLUTION | COILED COIL, TRANSMEMBRANE, THIOL PROTEASE, RNA REPLICATION, RIBOSOMAL FRAMESHIFTING, SERINE PROTEASE, CATALYTIC TRIAD, PROTEASE, MEMBRANE, HYDROLASE, ANTIVIRAL, ASTROVIRUS
1tbq:H (ARG206) to (THR229) CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN | COMPLEX (SERINE PROTEASE/INHIBITOR), KAZAL-TYPE INHIBITOR, THROMBIN
1tbr:H (ARG206) to (THR229) CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN | COMPLEX (SERINE PROTEASE-INHIBITOR), KAZAL-TYPE INHIBITOR, THROMBIN, COMPLEX (SERINE PROTEASE-INHIBITOR) COMPLEX
2gvf:C (GLY140) to (ILE170) HCV NS3-4A PROTEASE DOMAIN COMPLEXED WITH A MACROCYCLIC KETOAMIDE INHIBITOR, SCH419021 | HEPATITIS C, PROTEASE, KETOAMIDE INHIBITOR, HYDROLASE
4le7:B (GLN217) to (PRO252) THE CRYSTAL STRUCTURE OF PYOCIN L1 AT 2.09 ANGSTROMS | MONOCOT MANNOSE BINDING LECTIN, MMBL, GALANTHUS NIVALIS AGGLUTININ, GNA, BETA PRISM, BACTERIOCIN, PROTEIN ANTIMICROBIAL, SUGAR BINDING PROTEIN
1hia:Y (GLY197) to (THR229) KALLIKREIN COMPLEXED WITH HIRUSTASIN | COMPLEX (PROTEASE/INHIBITOR), TISSUE KALLIKREIN, SERINE PROTEASE, TRYPSIN, PSA, KININ, SERPIN
3is6:A (LYS168) to (PRO203) THE CRYSTAL STRUCTURE OF A DOMAIN OF A PUTATIVE PERMEASE PROTEIN FROM PORPHYROMONAS GINGIVALIS TO 2A | ABC, TRANSPORTER, PERMEASE, PORPHYROMONAS, GINGIVALIS, PSI, MCSG, STRUCTURAL GENOMICS, MIDWEST CENTER FOR STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, CELL MEMBRANE, MEMBRANE, TRANSMEMBRANE, TRANSPORT PROTEIN
1hne:E (SER197) to (ALA229) STRUCTURE OF HUMAN NEUTROPHIL ELASTASE IN COMPLEX WITH A PEPTIDE CHLOROMETHYL KETONE INHIBITOR AT 1.84-ANGSTROMS RESOLUTION | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1trn:B (GLY197) to (THR229) CRYSTAL STRUCTURE OF HUMAN TRYPSIN 1: UNEXPECTED PHOSPHORYLATION OF TYROSINE 151 | HUMAN TRYPSIN, DFP INHIBITED, HYDROLASE (SERINE PROTEINASE)
3vpl:A (ALA34) to (ILE61) CRYSTAL STRUCTURE OF A 2-FLUOROXYLOTRIOSYL COMPLEX OF THE VIBRIO SP. AX-4 BETA-1,3-XYLANASE | BETA-1, 3-XYLANASE, GLYCOSIDE HYDROLASE, TIM BARREL, HYDROLASE
5a09:A (SER197) to (ALA229) CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL ELASTASE IN COMPLEX WITH A DIHYDROPYRIMIDONE INHIBITOR | TRYPSIN FAMILY FOLD, PROTEASE, HYDROLASE, HYDROLASE- INHIBITOR COMPLEX
5a0a:E (SER197) to (ALA229) CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL ELASTASE IN COMPLEX WITH A DIHYDROPYRIMIDONE INHIBITOR | TRYPSIN FAMILY FOLD, PROTEASE, HYDROLASE, HYDROLASE- INHIBITOR COMPLEX
3vr4:B (ASP26) to (GLN50) CRYSTAL STRUCTURE OF ENTEROCOCCUS HIRAE V1-ATPASE [EV1] | V-ATPASE, ENTEROCOCCUS HIRAE, ROTARY MOTOR, P-LOOP, HYDROLASE, NA(+)- ATPASE, ATP BINDING
3vr5:B (ASP26) to (GLN50) CRYSTAL STRUCTURE OF NUCLEOTIDE-FREE ENTEROCOCCUS HIRAE V1-ATPASE [EV1(L)] | V-ATPASE, ENTEROCOCCUS HIRAE, ROTARY MOTOR, P-LOOP, HYDROLASE, NA(+)- ATPASE, ATP BINDING
3vr6:B (ASP26) to (GLN50) CRYSTAL STRUCTURE OF AMP-PNP BOUND ENTEROCOCCUS HIRAE V1-ATPASE [BV1] | V-ATPASE, ENTEROCOCCUS HIRAE, ROTARY MOTOR, P-LOOP, HYDROLASE, NA(+)- ATPASE, ATP BINDING
3iyj:F (ARG40) to (ALA63) BOVINE PAPILLOMAVIRUS TYPE 1 OUTER CAPSID | BOVINE PAPILLOMAVIRUS BPV1, MAJOR CAPSID PROTEIN L1, SINGLE PARTICLE CRYO-EM, HIGH RESOLUTION, CAPSID PROTEIN, LATE PROTEIN, VIRION, VIRUS
3iyj:A (ARG40) to (ALA63) BOVINE PAPILLOMAVIRUS TYPE 1 OUTER CAPSID | BOVINE PAPILLOMAVIRUS BPV1, MAJOR CAPSID PROTEIN L1, SINGLE PARTICLE CRYO-EM, HIGH RESOLUTION, CAPSID PROTEIN, LATE PROTEIN, VIRION, VIRUS
3iyj:C (ARG40) to (ALA63) BOVINE PAPILLOMAVIRUS TYPE 1 OUTER CAPSID | BOVINE PAPILLOMAVIRUS BPV1, MAJOR CAPSID PROTEIN L1, SINGLE PARTICLE CRYO-EM, HIGH RESOLUTION, CAPSID PROTEIN, LATE PROTEIN, VIRION, VIRUS
3iyj:D (ARG40) to (ALA63) BOVINE PAPILLOMAVIRUS TYPE 1 OUTER CAPSID | BOVINE PAPILLOMAVIRUS BPV1, MAJOR CAPSID PROTEIN L1, SINGLE PARTICLE CRYO-EM, HIGH RESOLUTION, CAPSID PROTEIN, LATE PROTEIN, VIRION, VIRUS
3iyj:E (ARG40) to (ALA63) BOVINE PAPILLOMAVIRUS TYPE 1 OUTER CAPSID | BOVINE PAPILLOMAVIRUS BPV1, MAJOR CAPSID PROTEIN L1, SINGLE PARTICLE CRYO-EM, HIGH RESOLUTION, CAPSID PROTEIN, LATE PROTEIN, VIRION, VIRUS
3vsg:C (GLN59) to (ASP89) CRYSTAL STRUCTURE OF IRON FREE 1,6-APD, 2-ANIMOPHENOL-1,6-DIOXYGENASE | EXTRADIOL DIOXYGENASE, CNBC, 2-HIS-1-CARBOXYLATE FACIAL TRIAD MOTIF, OXIDOREDUCTASE
3vsi:A (GLN59) to (ASP89) CRYSTAL STRUCTURE OF NATIVE 1,6-APD (2-ANIMOPHENOL-1,6-DIOXYGENASE) COMPLEX WITH 4-NITROCATECHOL | EXTRADIOL DIOXYGENASE, CNBC, 2-HIS-1-CARBOXYLATE FACIAL TRIAD MOTIF, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
1hxy:D (PRO24) to (ALA58) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN H IN COMPLEX WITH HUMAN MHC CLASS II | COMPLEX, IMMUNE SYSTEM/TOXIN COMPLEX
2hql:C (LYS62) to (ILE85) CRYSTAL STRUCTURE OF A SMALL SINGLE-STRANDED DNA BINDING PROTEIN FROM MYCOPLASMA PNEUMONIAE | STRUCTURAL GENOMICS, CONSERVED HYPOTHETICAL PROTEIN, MYCOPLASMA PNEUMONIAE, GI:1673959, MPN554, MG376, OB FOLD, SINGLE-STRANDED DNA BINDING PROTEIN, CRYSTAL STRUCTURE, PSI, PROTEIN STRUCTURE INITIATIVE, BERKELEY STRUCTURAL GENOMICS CENTER, BSGC
4lsr:G (GLY263) to (ASN289) CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC- CH31 IN COMPLEX WITH HIV-1 CLADE A/E STRAN 93TH057 GP120 WITH LOOP D AND LOOP V5 FROM CLADE A STRAIN KER_2018_11 | NEUTRALIZING ANTIBODY VRC-CH31, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
4lst:G (GLY263) to (LEU288) CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC01 IN COMPLEX WITH HIV-1 CLADE C STRAIN ZM176.66 GP120 | NEUTRALIZING ANTIBODY VRC01, HIV ENVELOPE GLYCOPROTEIN GP120, ANTIBODY ANTIGEN, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
1u2r:A (PRO559) to (PRO592) CRYSTAL STRUCTURE OF ADP-RIBOSYLATED RIBOSOMAL TRANSLOCASE FROM SACCHAROMYCES CEREVISIAE | ADP-RIBOSYLATION, EUKARYOTIC ELONGATION FACTOR 2, DIPHTHAMIDE, GDP, SORDARIN, TRANSLATION
2ht8:A (LYS95) to (LEU134) N8 NEURAMINIDASE IN COMPLEX WITH OSELTAMIVIR | N8, NEURAMINIDASE, OSELTAMIVIR, HYDROLASE
4lw3:A (ASP147) to (ARG190) CRYSTAL STRUCTURE OF THE DROSOPHILA BETA1,4GALACTOSYLTRANSFERASE7 CATALYTIC DOMAIN D211N SINGLE MUTANT ENZYME COMPLEX WITH MANGANESE AND UDP-GALACTOSE | GT-A GLYCOSYLTRANSFERASE FAMILY, MANGANESE AND UDP-GALACTOSE, GOLGI, TRANSFERASE
4lw6:A (ASP147) to (ARG190) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF DROSOPHILA BETA1, 4GALACTOSYLTRANSFERASE 7 COMPLEX WITH XYLOBIOSE | GT-A GLYCOSYLTRANSFERASE FAMILY, XYLOSE, GOLGI, TRANSFERASE
4ly6:O (GLU189) to (PHE226) NUCLEOTIDE-INDUCED ASYMMETRY WITHIN ATPASE ACTIVATOR RING DRIVES S54- RNAP INTERACTION AND ATP HYDROLYSIS | AAA+ ATPASE, BACTERIAL ENHANCER BINDING PROTEIN, S54-DEPENDENT TRANSCRIPTION ACTIVATOR, MOLECULAR MACHINE, SIGMA54, S54-RNAP, TRANSCRIPTION REGULATOR
1i8d:B (ALA40) to (MET64) CRYSTAL STRUCTURE OF RIBOFLAVIN SYNTHASE | RIBOFLAVIN SYNTHASE, RIBOFLAVIN BIOSYNTHESIS, ANTIMICROBIAL TARGET, STRUCTURE-BASED DESIGN, ESCHERICHIA COLI, TRANSFERASE
4lz4:B (ARG206) to (THR229) X-RAY STRUCTURE OF THE COMPLEX BETWEEN HUMAN THROMBIN AND THE TBA DELETION MUTANT LACKING THYMINE 3 NUCLEOBASE | PROTEIN-DNA COMPLEX, DNA APTAMER, G-QUADRUPLEX, TBA DELETION MUTANT, SERINE PROTEASE, HYDROLASE, BLOOD COAGULATION, BLOOD, HYDROLASE-DNA COMPLEX, HYDROLASE-HYDROLASE INHIBITOR-DNA COMPLEX
2hzi:A (ASN358) to (VAL379) ABL KINASE DOMAIN IN COMPLEX WITH PD180970 | TYROSINE KINASE, TRANSFERASE
1iai:H (THR115) to (PRO155) IDIOTYPE-ANTI-IDIOTYPE FAB COMPLEX | COMPLEX (IMMUNOGLOBULIN IGG1/IGG2A)
2i60:G (GLY263) to (LEU288) CRYSTAL STRUCTURE OF [PHE23]M47, A SCORPION-TOXIN MIMIC OF CD4, IN COMPLEX WITH HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN AND ANTI-HIV-1 ANTIBODY 17B | HIV-1, GP120, YU2, SCORPION TOXIN, CD4 MIMIC, [PHE23]M47, ANTIBODY, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
5a7x:A (GLY263) to (ASN289) NEGATIVE STAIN EM OF BG505 SOSIP.664 IN COMPLEX WITH SCD4, 17B, AND 8ANC195 | VIRAL PROTEIN
5a7x:I (GLY263) to (ASN289) NEGATIVE STAIN EM OF BG505 SOSIP.664 IN COMPLEX WITH SCD4, 17B, AND 8ANC195 | VIRAL PROTEIN
3j0j:A (GLY164) to (MET183) FITTED ATOMIC MODELS OF THERMUS THERMOPHILUS V-ATPASE SUBUNITS INTO CRYO-EM MAP | FLEXIBLE FITTING, RIGID BODY FITTING, MEMBRANE PROTEIN COMPLEX, HYDROLASE
3j0j:B (GLY164) to (MET183) FITTED ATOMIC MODELS OF THERMUS THERMOPHILUS V-ATPASE SUBUNITS INTO CRYO-EM MAP | FLEXIBLE FITTING, RIGID BODY FITTING, MEMBRANE PROTEIN COMPLEX, HYDROLASE
3j0j:C (GLY164) to (MET183) FITTED ATOMIC MODELS OF THERMUS THERMOPHILUS V-ATPASE SUBUNITS INTO CRYO-EM MAP | FLEXIBLE FITTING, RIGID BODY FITTING, MEMBRANE PROTEIN COMPLEX, HYDROLASE
5a8h:A (GLY263) to (ASN289) CRYO-ET SUBTOMOGRAM AVERAGING OF BG505 SOSIP.664 IN COMPLEX WITH SCD4, 17B, AND 8ANC195 | VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX, VIRUS
5a8h:G (GLY263) to (ASN289) CRYO-ET SUBTOMOGRAM AVERAGING OF BG505 SOSIP.664 IN COMPLEX WITH SCD4, 17B, AND 8ANC195 | VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX, VIRUS
5a8h:M (GLY263) to (ASN289) CRYO-ET SUBTOMOGRAM AVERAGING OF BG505 SOSIP.664 IN COMPLEX WITH SCD4, 17B, AND 8ANC195 | VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX, VIRUS
5a8x:A (SER197) to (ALA229) CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL ELASTASE IN COMPLEX WITH A DIHYDROPYRIMIDONE INHIBITOR | TRYPSIN FAMILY FOLD, PROTEASE, HYDROLASE, HYDROLASE- INHIBITOR COMPLEX
4m46:A (ARG337) to (GLY394) CRYSTAL STRUCTURE OF A GREEN-EMITTER NATIVE OF LAMPYRIS TURKESTANICUS LUCIFERASE | BIOLUMINESCENCE, OXIDOREDUCTASE ACTIVITY, MONOOXYGENASE, ATP BINDING, OXIDOREDUCTASE, LUCIFERIN-BINDING, LIGHT EMITTING
4m6j:A (LYS155) to (ASN185) CRYSTAL STRUCTURE OF HUMAN DIHYDROFOLATE REDUCTASE (DHFR) BOUND TO NADPH | ROSSMANN FOLD, NADPH BINDING, FOLATE BINDING, OXIDOREDUCTASE
4m8n:B (GLY755) to (LEU806) CRYSTAL STRUCTURE OF PLEXINC1/RAP1B COMPLEX | GTPASE, GTPASE ACTIVATING PROTEIN, RAP,GTP BINDING, MAGNESIUM BINDING, MEMBRANE, SIGNALING PROTEIN
4mb3:A (VAL33) to (GLU55) CRYSTAL STRUCTURE OF E153Q MUTANT OF COLD-ADAPTED CHITINASE FROM MORITELLA MARINA | TIM-BARREL, ALPHA/BETA-BARREL IG-LIKE, IMMUNOGLOBULIN LIKE DOMAIN, CHBD, CHITIN BINDING DOMAIN, NAG4, CHITINASE, HYDROLAZE, LOW ACTIVITY MUTANT, HYDROLASE
4mb4:A (VAL33) to (GLU55) CRYSTAL STRUCTURE OF E153Q MUTANT OF COLD-ADAPTED CHITINASE FROM MORITELLA COMPLEX WITH NAG4 | TIM-BARREL, ALPHA/BETA-BARREL IG-LIKE, IMMUNOGLOBULIN LIKE DOMAIN, CHBD, CHITIN BINDING DOMAIN, NAG4, CHITINASE, HYDROLAZE, LOW ACTIVITY MUTANT, HYDROLASE
2igt:A (ARG79) to (PHE104) CRYSTAL STRUCTURE OF THE SAM DEPENDENT METHYLTRANSFERASE FROM AGROBACTERIUM TUMEFACIENS | ALPHA-BETA SANDWICH, BETA-BARREL, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, TRANSFERASE
2igt:B (ARG79) to (PHE104) CRYSTAL STRUCTURE OF THE SAM DEPENDENT METHYLTRANSFERASE FROM AGROBACTERIUM TUMEFACIENS | ALPHA-BETA SANDWICH, BETA-BARREL, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, TRANSFERASE
1uvt:H (ARG206) to (THR229) BOVINE THROMBIN--BM14.1248 COMPLEX | SERINE PROTEASE, HYDROLASE, THROMBIN, BLOOD COAGULATION
2in2:A (GLY154) to (ALA171) NMR STRUCTURE OF THE APO HUMAN RHINOVIRUS 3C PROTEASE (SEROTYPE 14) | HYDROLASE, PROTEASE, BETA BARREL, RNA BINDING, RNA POLYMERASE BINDING
4mg3:B (GLY112) to (ALA135) CRYSTAL STRUCTURAL ANALYSIS OF 2A PROTEASE FROM COXSACKIEVIRUS A16 | BETA BARREL, HYDROLASE
2x4w:A (PRO1100) to (PRO1123) MOLECULAR BASIS OF HISTONE H3K36ME3 RECOGNITION BY THE PWWP DOMAIN OF BRPF1. | TRANSCRIPTION, METAL-BINDING, ZINC-FINGER, CHROMATIN REGULATOR, TRANSCRIPTION REGULATION
2iq7:A (ASN243) to (GLY272) CRYSTAL STRUCTURE OF THE POLYGALACTURONASE FROM COLLETOTRICHUM LUPINI AND ITS IMPLICATIONS FOR THE INTERACTION WITH POLYGALACTURONASE- INHIBITING PROTEINS | PARALLEL BETA HELIX, HYDROLASE
2iq7:B (ASN243) to (GLY272) CRYSTAL STRUCTURE OF THE POLYGALACTURONASE FROM COLLETOTRICHUM LUPINI AND ITS IMPLICATIONS FOR THE INTERACTION WITH POLYGALACTURONASE- INHIBITING PROTEINS | PARALLEL BETA HELIX, HYDROLASE
2iq7:C (ASN243) to (GLY272) CRYSTAL STRUCTURE OF THE POLYGALACTURONASE FROM COLLETOTRICHUM LUPINI AND ITS IMPLICATIONS FOR THE INTERACTION WITH POLYGALACTURONASE- INHIBITING PROTEINS | PARALLEL BETA HELIX, HYDROLASE
2iq7:E (ASN243) to (GLY272) CRYSTAL STRUCTURE OF THE POLYGALACTURONASE FROM COLLETOTRICHUM LUPINI AND ITS IMPLICATIONS FOR THE INTERACTION WITH POLYGALACTURONASE- INHIBITING PROTEINS | PARALLEL BETA HELIX, HYDROLASE
2iq7:G (ASN243) to (GLY272) CRYSTAL STRUCTURE OF THE POLYGALACTURONASE FROM COLLETOTRICHUM LUPINI AND ITS IMPLICATIONS FOR THE INTERACTION WITH POLYGALACTURONASE- INHIBITING PROTEINS | PARALLEL BETA HELIX, HYDROLASE
1v1o:A (SER34) to (LEU69) STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN 7 | VIRULENCE FACTOR, ANTIGEN PRESENTING CELL, SECRETED PROTEIN, STAPHYLOCOCCAL EXOTOXIN 1, SET1
2iru:B (PRO64) to (PRO94) CRYSTAL STRUCTURE OF THE POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D | POLYMERASE, PRIMASE, LIGASE, NHEJ, TRANSFERASE
1v47:A (LEU59) to (VAL87) CRYSTAL STRUCTURE OF ATP SULFURYLASE FROM THERMUS THERMOPHILLUS HB8 IN COMPLEX WITH APS | PRODUCT BINDING COMPLEX, ZINC, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
4mj1:D (GLY251) to (LYS296) UNLIGANDED BK POLYOMAVIRUS VP1 PENTAMER | ANTIPARALLEL BETA SANDWICH, JELLY-ROLL TOPOLOGY, VIRAL PROTEIN, POLYOMAVIRUS, RECEPTOR SWITCH, VIRUS MAJOR CAPSID PROTEIN, ATTACHMENT TO HOST-CELL SURFACE RECEPTORS
1v5v:B (TYR330) to (PHE359) CRYSTAL STRUCTURE OF A COMPONENT OF GLYCINE CLEAVAGE SYSTEM: T-PROTEIN FROM PYROCOCCUS HORIKOSHII OT3 AT 1.5 A RESOLUTION | GLYCINE-CLEAVAGE SYTEM, AMINOMETHYL TRANSFERASE, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
4mky:C (PRO64) to (PRO94) POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D IN COMPLEX WITH AN ANNEALED DOUBLE-STRAND DNA BREAK. | PROTEIN-DNA COMPLEX, TRANSFERASE-DNA COMPLEX, NUCLEOTIDE-BINDING, POLYMERASE, PRIMASE, TRANSFERASE
4mky:D (PRO64) to (PRO94) POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D IN COMPLEX WITH AN ANNEALED DOUBLE-STRAND DNA BREAK. | PROTEIN-DNA COMPLEX, TRANSFERASE-DNA COMPLEX, NUCLEOTIDE-BINDING, POLYMERASE, PRIMASE, TRANSFERASE
4mlg:K (GLU198) to (SER239) STRUCTURE OF RS223-BETA-XYLOSIDASE | BETA-PROPELLER, BETA-XYLOSIDASE, HYDROLASE
2xcn:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR | HYDROLASE, SERINE PROTEASE
2xcn:B (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR | HYDROLASE, SERINE PROTEASE
3wqe:B (GLN300) to (ALA325) D-THREO-3-HYDROXYASPARTATE DEHYDRATASE FROM DELFTIA SP. HT23 COMPLEXED WITH D-ALLOTHREONINE | DEHYDRATASE, PLP, LYASE
3wqd:B (GLN300) to (ALA325) D-THREO-3-HYDROXYASPARTATE DEHYDRATASE FROM DELFTIA SP. HT23 COMPLEXED WITH D-ERYTHRO-3-HYDROXYASPARTATE | DEHYDRATASE, PLP, LYASE
3wqf:B (GLN300) to (ALA325) D-THREO-3-HYDROXYASPARTATE DEHYDRATASE FROM DELFTIA SP. HT23 IN THE METAL-FREE FORM | DEHYDRATASE, PLP, LYASE
3wqg:B (GLN300) to (ALA325) D-THREO-3-HYDROXYASPARTATE DEHYDRATASE C353A MUTANT IN THE METAL-FREE FORM | DEHYDRATASE, PLP, LYASE
1vgc:C (ALA179) to (GLY211) GAMMA-CHYMOTRYPSIN L-PARA-CHLORO-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX | HYDROLASE, SERINE PROTEASE
1jmo:H (ARG206) to (THR229) CRYSTAL STRUCTURE OF THE HEPARIN COFACTOR II-S195A THROMBIN COMPLEX | SERPIN, THROMBIN, PROTEASE, INHIBITION, INHIBITOR, BLOOD CLOTTING
1vj9:U (GLY197) to (THR229) UROKINASE PLASMINOGEN ACTIVATOR B-CHAIN-JT464 COMPLEX | UROKINASE, INHIBITOR, SERINE PROTEASE, HUMAN, HYDROLASE
2j5u:A (GLN222) to (ALA262) MREC LYSTERIA MONOCYTOGENES | BACTERIAL CELL SHAPE DETERMINING PROTEIN MREC, CELL SHAPE REGULATION
2j5u:B (GLN222) to (ALA262) MREC LYSTERIA MONOCYTOGENES | BACTERIAL CELL SHAPE DETERMINING PROTEIN MREC, CELL SHAPE REGULATION
4msp:B (GLN54) to (GLY118) CRYSTAL STRUCTURE OF HUMAN PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP22 (AKA FKBP14) CONTAINING TWO EF-HAND MOTIFS | FKBP-TYPE DOMAIN, EF-HAND MOTIF, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE, CALCIUM BINDING, ENDOPLASMIC RETICULUM, ISOMERASE
1jou:D (ARG206) to (THR229) CRYSTAL STRUCTURE OF NATIVE S195A THROMBIN WITH AN UNOCCUPIED ACTIVE SITE | PROTEASE, PROTEINASE, THROMBIN, FACTOR IIA, ENZYME, BLOOD CLOTTING
4mtk:D (VAL7) to (GLU42) CRYSTAL STRUCTURE OF PA0091 VGRG1, THE CENTRAL SPIKE OF THE TYPE VI SECRETION SYSTEM | BETA-BARREL, OB-FOLD, BETA-HELIX, TYPE VI SECRETION SYSTEM CENTRAL SPIKE, SECRETED OUTSIDE OF THE CELL, TOXIN
3j6r:D (LEU42) to (GLY67) ELECTRON CRYO-MICROSCOPY OF HUMAN PAPILLOMAVIRUS TYPE 16 CAPSID | CAPSID PROTEIN, VIRUS
3j6r:C (LEU42) to (GLY67) ELECTRON CRYO-MICROSCOPY OF HUMAN PAPILLOMAVIRUS TYPE 16 CAPSID | CAPSID PROTEIN, VIRUS
3j7g:A (LEU42) to (GLY67) ELECTRON CRYO-MICROSCOPY OF HUMAN PAPILLOMAVIRUS 16 AND H16.V5 FAB FRAGMENTS | PENTAMER OF HUMAN PAPILLOMAVIRUS, QV16-V5 COMPLEX, VIRUS-FAB COMPLEX, NEUTRALIZATION ANTIBODY, MATURATION, VIRUS
3j7g:C (LEU42) to (GLY67) ELECTRON CRYO-MICROSCOPY OF HUMAN PAPILLOMAVIRUS 16 AND H16.V5 FAB FRAGMENTS | PENTAMER OF HUMAN PAPILLOMAVIRUS, QV16-V5 COMPLEX, VIRUS-FAB COMPLEX, NEUTRALIZATION ANTIBODY, MATURATION, VIRUS
3j7g:D (LEU42) to (GLY67) ELECTRON CRYO-MICROSCOPY OF HUMAN PAPILLOMAVIRUS 16 AND H16.V5 FAB FRAGMENTS | PENTAMER OF HUMAN PAPILLOMAVIRUS, QV16-V5 COMPLEX, VIRUS-FAB COMPLEX, NEUTRALIZATION ANTIBODY, MATURATION, VIRUS
3j7g:E (LEU42) to (GLY67) ELECTRON CRYO-MICROSCOPY OF HUMAN PAPILLOMAVIRUS 16 AND H16.V5 FAB FRAGMENTS | PENTAMER OF HUMAN PAPILLOMAVIRUS, QV16-V5 COMPLEX, VIRUS-FAB COMPLEX, NEUTRALIZATION ANTIBODY, MATURATION, VIRUS
2ja5:B (GLY902) to (LEU941) CPD LESION CONTAINING RNA POLYMERASE II ELONGATION COMPLEX A | DNA-DIRECTED RNA POLYMERASE, LESION RECOGNITION, TRANSFERASE/DNA/RNA, DNA DAMAGE, ZINC-FINGER, DNA-BINDING, PHOTOLESION, PHOSPHORYLATION, MISINCORPORATION, RNA POLYMERASE II, TRANSCRIPTION- COUPLED REPAIR, CYCLOBUTANE PYRIMIDINE DIMER, TCR, CPD, ZINC, ARREST, STALLING, DNA LESION, METAL-BINDING, NUCLEAR PROTEIN, TRANSCRIPTION BUBBLE, NUCLEOTIDYLTRANSFERASE, DAMAGE RECOGNITION, ELONGATION COMPLEX, TRANSFERASE, THYMINE DIMER, TRANSCRIPTION
5az4:A (TYR193) to (VAL229) CRYSTAL STRUCTURE OF A 79KDA FRAGMENT OF FLGE, THE HOOK PROTEIN FROM CAMPYLOBACTER JEJUNI | FLAGELLUM, HOOK, UNIVERSAL JOINT, MOTOR PROTEIN
2xn9:C (PRO24) to (ALA58) CRYSTAL STRUCTURE OF THE TERNARY COMPLEX BETWEEN HUMAN T CELL RECEPTOR, STAPHYLOCOCCAL ENTEROTOXIN H AND HUMAN MAJOR HISTOCOMPATIBILITY COMPLEX CLASS II | IMMUNE SYSTEM, SUPERANTIGEN, IMMUNORECEPTORS, TERNARY COMPLEX
2xna:C (PRO24) to (ALA58) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN HUMAN T CELL RECEPTOR AND STAPHYLOCOCCAL ENTEROTOXIN | IMMUNE SYSTEM, SUPERANTIGEN
3j8v:A (LEU42) to (GLY67) CRYO-EM RECONSTRUCTION OF QUASI-HPV16 COMPLEX WITH H16.14J FAB | L1 PENTAMER, QUASI-HPV16, L1 CAPSOMER, ROSIE ONLINE, VIRUS-IMMUNE SYSTEM COMPLEX
3j8v:C (LEU42) to (GLY67) CRYO-EM RECONSTRUCTION OF QUASI-HPV16 COMPLEX WITH H16.14J FAB | L1 PENTAMER, QUASI-HPV16, L1 CAPSOMER, ROSIE ONLINE, VIRUS-IMMUNE SYSTEM COMPLEX
3j8v:D (LEU42) to (GLY67) CRYO-EM RECONSTRUCTION OF QUASI-HPV16 COMPLEX WITH H16.14J FAB | L1 PENTAMER, QUASI-HPV16, L1 CAPSOMER, ROSIE ONLINE, VIRUS-IMMUNE SYSTEM COMPLEX
3j8v:E (LEU42) to (GLY67) CRYO-EM RECONSTRUCTION OF QUASI-HPV16 COMPLEX WITH H16.14J FAB | L1 PENTAMER, QUASI-HPV16, L1 CAPSOMER, ROSIE ONLINE, VIRUS-IMMUNE SYSTEM COMPLEX
2xni:A (GLY140) to (ILE170) PROTEIN-LIGAND COMPLEX OF A NOVEL MACROCYCLIC HCV NS3 PROTEASE INHIBITOR DERIVED FROM AMINO CYCLIC BORONATES | HYDROLASE-HYDROLASE REGULATOR COMPLEX, SERINE PROTEASE
2xni:B (GLY140) to (ILE170) PROTEIN-LIGAND COMPLEX OF A NOVEL MACROCYCLIC HCV NS3 PROTEASE INHIBITOR DERIVED FROM AMINO CYCLIC BORONATES | HYDROLASE-HYDROLASE REGULATOR COMPLEX, SERINE PROTEASE
3j8w:A (LEU42) to (GLY67) CRYO-EM RECONSTRUCTION OF QUASI-HPV16 COMPLEX WITH H263.A2 FAB | L1 PENTAMER, QUASI-HPV16, L1 CAPSOMER, ROSIE ONLINE, VIRUS-IMMUNE SYSTEM COMPLEX
3j8w:C (LEU42) to (GLY67) CRYO-EM RECONSTRUCTION OF QUASI-HPV16 COMPLEX WITH H263.A2 FAB | L1 PENTAMER, QUASI-HPV16, L1 CAPSOMER, ROSIE ONLINE, VIRUS-IMMUNE SYSTEM COMPLEX
3j8w:D (LEU42) to (GLY67) CRYO-EM RECONSTRUCTION OF QUASI-HPV16 COMPLEX WITH H263.A2 FAB | L1 PENTAMER, QUASI-HPV16, L1 CAPSOMER, ROSIE ONLINE, VIRUS-IMMUNE SYSTEM COMPLEX
3j8w:E (LEU42) to (GLY67) CRYO-EM RECONSTRUCTION OF QUASI-HPV16 COMPLEX WITH H263.A2 FAB | L1 PENTAMER, QUASI-HPV16, L1 CAPSOMER, ROSIE ONLINE, VIRUS-IMMUNE SYSTEM COMPLEX
4n00:A (THR120) to (GLU140) DISCOVERY OF 7-THP CHROMANS: BACE1 INHIBITORS THAT REDUCE A-BETA IN THE CNS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3j8z:A (LEU42) to (GLY67) CRYO-EM RECONSTRUCTION OF QUASI-HPV16 COMPLEX WITH H16.1A FAB | L1 PENTAMER, QUASI-HPV16, L1 CAPSOMER, ROSIE ONLINE, VIRUS-IMMUNE SYSTEM COMPLEX
3j8z:C (LEU42) to (GLY67) CRYO-EM RECONSTRUCTION OF QUASI-HPV16 COMPLEX WITH H16.1A FAB | L1 PENTAMER, QUASI-HPV16, L1 CAPSOMER, ROSIE ONLINE, VIRUS-IMMUNE SYSTEM COMPLEX
3j8z:D (LEU42) to (GLY67) CRYO-EM RECONSTRUCTION OF QUASI-HPV16 COMPLEX WITH H16.1A FAB | L1 PENTAMER, QUASI-HPV16, L1 CAPSOMER, ROSIE ONLINE, VIRUS-IMMUNE SYSTEM COMPLEX
3j8z:E (LEU42) to (GLY67) CRYO-EM RECONSTRUCTION OF QUASI-HPV16 COMPLEX WITH H16.1A FAB | L1 PENTAMER, QUASI-HPV16, L1 CAPSOMER, ROSIE ONLINE, VIRUS-IMMUNE SYSTEM COMPLEX
1w18:B (THR283) to (PHE326) CRYSTAL STRUCTURE OF LEVANSUCRASE FROM GLUCONACETOBACTER DIAZOTROPHICUS | TRANSFERASE, FRUCTOSYL TRANSFERASE, GLYCOSYLTRANSFERASE
2xnx:H (ILE252) to (GLU291) BC1 FRAGMENT OF STREPTOCOCCAL M1 PROTEIN IN COMPLEX WITH HUMAN FIBRINOGEN | CELL ADHESION, VIRULENCE FACTOR, STREPTOCOCCAL TOXIC SHOCK SYNDROME
2xnx:K (ILE252) to (GLU291) BC1 FRAGMENT OF STREPTOCOCCAL M1 PROTEIN IN COMPLEX WITH HUMAN FIBRINOGEN | CELL ADHESION, VIRULENCE FACTOR, STREPTOCOCCAL TOXIC SHOCK SYNDROME
1jxp:A (GLY140) to (VAL170) BK STRAIN HEPATITIS C VIRUS (HCV) NS3-NS4A | COMPLEX (VIRAL NONSTRUCTURAL PROTEINS), HYDROLASE, SERINE PROTEINASE, VIRAL PROTEIN COMPLEX
2ja8:B (GLY902) to (LEU941) CPD LESION CONTAINING RNA POLYMERASE II ELONGATION COMPLEX D | DNA-DIRECTED RNA POLYMERASE, LESION RECOGNITION, TRANSFERASE/DNA/RNA, DNA DAMAGE, ZINC-FINGER, DNA-BINDING, PHOTOLESION, PHOSPHORYLATION, MISINCORPORATION, RNA POLYMERASE II, TRANSCRIPTION-COUPLED REPAIR, CYCLOBUTANE PYRIMIDINE DIMER TCR, CPD, ARREST, STALLING, DNA LESION, METAL-BINDING, NUCLEAR PROTEIN, TRANSCRIPTION BUBBLE, NUCLEOTIDYLTRANSFERASE, DAMAGE RECOGNITION, ELONGATION COMPLEX, TRANSFERASE, THYMINE DIMER, TRANSCRIPTION
2xq1:B (GLY68) to (ARG98) CRYSTAL STRUCTURE OF PEROXISOMAL CATALASE FROM THE YEAST HANSENULA POLYMORPHA | OXIDOREDUCTASE, HYDROGEN PEROXIDE DETOXIFICATION, PTS1
2xqr:E (ASN19) to (GLN39) CRYSTAL STRUCTURE OF PLANT CELL WALL INVERTASE IN COMPLEX WITH A SPECIFIC PROTEIN INHIBITOR | HYDROLASE-INHIBITOR COMPLEX, APOPLAST, CELL WALL, HYDROLASE, PROTEIN INHIBITOR, SUGAR METABOLISM, GLYCOSIDASE
2xqr:I (ASN19) to (GLN39) CRYSTAL STRUCTURE OF PLANT CELL WALL INVERTASE IN COMPLEX WITH A SPECIFIC PROTEIN INHIBITOR | HYDROLASE-INHIBITOR COMPLEX, APOPLAST, CELL WALL, HYDROLASE, PROTEIN INHIBITOR, SUGAR METABOLISM, GLYCOSIDASE
2xrc:B (GLU489) to (GLY524) HUMAN COMPLEMENT FACTOR I | IMMUNE SYSTEM, HYDROLASE, CONGLUTINOGEN ACTIVATING FACTOR, SERINE PROTEASE, COMPLEMENT SYSTEM
2xrc:D (GLU489) to (GLY524) HUMAN COMPLEMENT FACTOR I | IMMUNE SYSTEM, HYDROLASE, CONGLUTINOGEN ACTIVATING FACTOR, SERINE PROTEASE, COMPLEMENT SYSTEM
3j9u:C (GLU47) to (GLN71) YEAST V-ATPASE STATE 2 | V-ATPASE, V-TYPE ATPASE, VACUOLAR-TYPE ATPASE, PROTON PUMP, HYDROLASE
3j9u:E (ASP150) to (LEU174) YEAST V-ATPASE STATE 2 | V-ATPASE, V-TYPE ATPASE, VACUOLAR-TYPE ATPASE, PROTON PUMP, HYDROLASE
1w44:A (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH ADP | VIRUS DSRNA, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w44:B (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH ADP | VIRUS DSRNA, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w44:C (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH ADP | VIRUS DSRNA, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w46:A (ASP55) to (GLU87) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH ADP AND MG | DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w46:B (ASP55) to (GLU87) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH ADP AND MG | DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w46:C (ASP55) to (GLU87) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH ADP AND MG | DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w47:A (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH ADP AND MN | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE
1w47:B (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH ADP AND MN | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE
1w47:C (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH ADP AND MN | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE
1w48:A (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH AMPCPP | DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w48:B (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH AMPCPP | DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w48:C (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH AMPCPP | DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w49:A (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH AMPCPP AND MG | DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w49:B (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH AMPCPP AND MG | DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w49:C (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH AMPCPP AND MG | DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w4a:B (ASP55) to (ASN88) P4 PROTEIN FROM PHI12 IN COMPLEX WITH AMPCPP AND MN | VIRUS DSRNA, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w4b:A (ASP55) to (GLU87) P4 PROTEIN FROM PHI12 IN COMPLEX WITH PRODUCT (AMPCPP MG 22C) | VIRUS DSRNA, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w4b:B (ASP55) to (GLU87) P4 PROTEIN FROM PHI12 IN COMPLEX WITH PRODUCT (AMPCPP MG 22C) | VIRUS DSRNA, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w4b:C (ASP55) to (GLU87) P4 PROTEIN FROM PHI12 IN COMPLEX WITH PRODUCT (AMPCPP MG 22C) | VIRUS DSRNA, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
5b5r:A (MSE155) to (PRO199) CRYSTAL STRUCTURE OF GSDMA3 | PYROPTOSIS EXCUTIONER, TRANSPORT PROTEIN
5bn5:A (GLU22) to (GLN46) STRUCTURAL BASIS FOR A UNIQUE ATP SYNTHASE CORE COMPLEX FROM NANOARCHEAUM EQUITANS | ATP SYNTHASE, NANOARCHEAUM EQUITANS, CATALYTIC CORE, HYDROLASE
1w91:D (ASP223) to (GLU246) CRYSTAL STRUCTURE OF 1,4-BETA-D-XYLAN XYLOHYDROLASE SOLVE USING ANOMALOUS SIGNAL FROM SELENIOMETHIONINE | XYLOSIDASE, MAD, SEMET, TETRAMER, HYDROLASE
5brr:E (GLY197) to (THR229) MICHAELIS COMPLEX OF TPA-S195A:PAI-1 | TISSUE-TYPE PLASMINOGEN ACTIVATOR CATALYTIC DOMAIN, PLASMINOGEN ACTIVATOR INHIBITOR 1, STRUCTURE-ACTIVITY RELATIONSHIP, THROMBOLYSIS, HYDROLASE INHIBITOR-HYDROLASE COMPLEX
4nbz:A (ASN106) to (GLY133) CRYSTAL STRUCTURE OF TCDA-A1 BOUND TO A26.8 VHH | ANTIBODY-ANTIGEN COMPLEX, IMMUNE SYSTEM
1k3c:A (GLY227) to (GLY248) PHOSPHOENOLPYRUVATE CARBOXYKINASE IN COMPLEX WITH ADP, ALF3 AND PYRUVATE | KINASE, P-LOOP, GLUCONEOGENESIS, NUCLEOTIDE-TRIPHOSPHATE HYDROLASE, LYASE
1k3d:A (GLY227) to (GLY248) PHOSPHOENOLPYRUVATE CARBOXYKINASE IN COMPLEX WITH ADP AND ALF3 | KINASE, GLUCONEOGENESIS, NUCLEOTIDE-TRIPHOSPHATE HYDROLASE., LYASE
5bur:A (PHE376) to (PRO396) O-SUCCINYLBENZOATE COENZYME A SYNTHETASE (MENE) FROM BACILLUS SUBTILIS, IN COMPLEX WITH ATP AND MAGNESIUM ION | ATP, ENZYME MECHANISM, PROTEIN CONFORMATION, VITAMIN K2, ADENYLATE FORMING ENZYME, DOMAIN ALTERATION, OPEN-CLOSED CONFORMATIONAL CHANGE, LIGASE
4nei:A (PHE560) to (ASN585) ALG17C PL17 FAMILY ALGINATE LYASE | PL17, LYASE
4nei:B (PHE560) to (ASN585) ALG17C PL17 FAMILY ALGINATE LYASE | PL17, LYASE
2jqx:A (SER177) to (LYS203) SOLUTION STRUCTURE OF MALATE SYNTHASE G FROM JOINT REFINEMENT AGAINST NMR AND SAXS DATA | APO-MALATE SYNTHASE G, 82 KDA ENZYME, SAXS, SMALL-ANGLE X- RAY SCATTERING, RDC, RESIDUAL DIPOLAR COUPLING, RESIDUAL CHEMICAL SHIFT ANISOTROPY, ALIGNMENT, DEUTERATION, TRANSFERASE
1k83:B (GLY902) to (LEU941) CRYSTAL STRUCTURE OF YEAST RNA POLYMERASE II COMPLEXED WITH THE INHIBITOR ALPHA AMANITIN | TRANSCRIPTION-TOXIN COMPLEX, ALPHA AMANITIN, TOXIN, INHIBITOR, POLYMERASE, TRANSFERASE, DNA BINDING, ZINC-FINGER, PHOSPHOPROTEIN, TRANSCRIPTION, UBL TRANSCRIPTION-TOXIN COMPLEX
2jwp:A (ILE11) to (ARG30) MALECTIN | LECTIN, SUGAR BINDING, SUGAR BINDING PROTEIN
3zkr:D (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH BROMOFORM | TRANSPORT PROTEIN, CYS-LOOP RECEPTOR, GABA-A RECEPTOR, GENERAL ANESTHETICS
2kt1:A (PHE7) to (PRO27) SOLUTION NMR STRUCTURE OF THE SH3 DOMAIN FROM THE P85BETA SUBUNIT OF PHOSPHATIDYLINOSITOL 3-KINASE FROM H.SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR5531E | STRUCTURAL GENOMICS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG), TARGET HR5531E, PSI-2, PROTEIN STRUCTURE INITIATIVE, P85BETA SUBUNIT OF PI3K, SH3 DOMAIN, PHOSPHOPROTEIN, POLYMORPHISM
3znn:A (GLY277) to (TYR309) IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN | OXIDOREDUCTASE, FLAVOOXIDASE, NEUROTRANSMISSION
3zno:A (GLY277) to (GLY312) IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN | OXIDOREDUCTASE, NEUROTRANSMISSION
1wqv:H (THR206) to (THR229) HUMAN FACTOR VIIA-TISSUE FACTOR COMPLEXED WITH PROPYLSULFONAMIDE-D- THR-MET-P-AMINOBENZAMIDINE | SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1wss:H (THR206) to (THR229) HUMAN FACTOR VIIA-TISSUE FACTOR IN COMPLEX WITH PEPTIDE-MIMETIC INHIBITOR THAT HAS TWO CHARGED GROUPS IN P2 AND P4 | SERINE PROTEASE, HYDROLASE-BLOOD CLOTTING COMPLEX
1wtg:H (THR206) to (THR229) HUMAN FACTOR VIIA-TISSUE FACTOR COMPLEXED WITH ETHYLSULFONAMIDE-D-BIPHENYLALANINE-GLN-P-AMINOBENZAMIDINE | SERINE PROTEASE, HYDROLASE/BLOOD CLOTTING COMPLEX
5c1e:A (SER262) to (ASN288) CRYSTAL STRUCTURE OF THE PECTIN METHYLESTERASE FROM ASPERGILLUS NIGER IN PENULTIMATELY DEGLYCOSYLATED FORM (N-ACETYLGLUCOSAMINE STUB AT ASN84) | PARALLEL BETA HELIX, PECTIN METHYLESTERASE, HYDROLASE
5c1u:B (GLY148) to (ALA172) CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND XB | HYDROLASE, CYSTEINE PROTEINASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1wv7:H (THR206) to (THR229) HUMAN FACTOR VIIA-TISSUE FACTOR COMPLEXED WITH ETHYLSULFONAMIDE-D-5-PROPOXY-TRP-GLN-P-AMINOBENZAMIDINE | SERINE PROTEASE, HYDROLASE/BLOOD CLOTTING COMPLEX
2lq8:A (ASP127) to (ASN156) DOMAIN INTERACTION IN THERMOTOGA MARITIMA NUSG | TRANSCRIPTION
5c3e:B (VAL903) to (LEU941) CRYSTAL STRUCTURE OF A TRANSCRIBING RNA POLYMERASE II COMPLEX REVEALS A COMPLETE TRANSCRIPTION BUBBLE | PROTEIN-DNA COMPLEX, RNA POLYERMASE II, TRANSCRIBING COMPLEX, TRANSFERASE-DNA-RNA COMPLEX
1klt:A (GLY196) to (THR229) CRYSTAL STRUCTURE OF PMSF-TREATED HUMAN CHYMASE AT 1.9 ANGSTROMS RESOLUTION | SERINE PROTEASE, HYDROLASE, MAST CELL, ANGIOTENSIN, ALPHA TOLUENESULFONIC ACID
3zu0:B (LYS33) to (PHE70) STRUCTURE OF HAEMOPHILUS INFLUENZAE NAD NUCLEOTIDASE (NADN) | HYDROLASE, PERIPLASMIC ENZYME HAEMOPHILUS INFLUENZAE, CD73
4nsy:A (SER196) to (GLY228) WILD-TYPE LYSOBACTER ENZYMOGENES LYSC ENDOPROTEINASE COVALENTLY INHIBITED BY TLCK | HYDROLASE, ENDOPROTEINASE, AROMATIC STACK, ATOMIC RESOLUTION, SERINE PROTEASE, CATALYTIC TRIAD, COVALENT INHIBITION, TLCK, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4nsy:B (SER196) to (GLY228) WILD-TYPE LYSOBACTER ENZYMOGENES LYSC ENDOPROTEINASE COVALENTLY INHIBITED BY TLCK | HYDROLASE, ENDOPROTEINASE, AROMATIC STACK, ATOMIC RESOLUTION, SERINE PROTEASE, CATALYTIC TRIAD, COVALENT INHIBITION, TLCK, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
2yew:I (CYS27) to (SER50) MODELING BARMAH FOREST VIRUS STRUCTURAL PROTEINS | ALPHAVIRUS, VIRUS, MOLECULAR DYNAMICS
5c4w:A (ALA29) to (HIS72) CRYSTAL STRUCTURE OF COXSACKIEVIRUS A16 | HAND-FOOT-AND-MOUTH DISEASE, IMMUNOGENICITY, PICORNAVIRUS, ICOSAHEDRAL VIRUS, VIRUS
4nwl:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HEPATIS C VIRUS PROTEASE (NS3) COMPLEXED WITH BMS-650032 AKA N-(TERT-BUTOXYCARBONYL)-3-ME THYL-L-VALYL-(4R)-4-((7- CHLORO-4-METHOXY-1-ISOQUINOLINYL)O XY)-N-((1R,2S)-1- ((CYCLOPROPYLSULFONYL)CARBAMOYL)-2-VINYLC YCLOPROPYL)-L-PROLINAMIDE | HYDROLASE/HYDROLASE INHIBITOR, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4nwl:B (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HEPATIS C VIRUS PROTEASE (NS3) COMPLEXED WITH BMS-650032 AKA N-(TERT-BUTOXYCARBONYL)-3-ME THYL-L-VALYL-(4R)-4-((7- CHLORO-4-METHOXY-1-ISOQUINOLINYL)O XY)-N-((1R,2S)-1- ((CYCLOPROPYLSULFONYL)CARBAMOYL)-2-VINYLC YCLOPROPYL)-L-PROLINAMIDE | HYDROLASE/HYDROLASE INHIBITOR, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3jcm:H (PRO673) to (PRO714) CRYO-EM STRUCTURE OF THE SPLICEOSOMAL U4/U6.U5 TRI-SNRNP | U4/U6.U5 TRI-SNRNP, PRE-MRNA, TRANSCRIPTION
2n0a:B (GLY73) to (ALA90) ATOMIC-RESOLUTION STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS | PROTEIN FIBRIL, AMYLOID, PARKINSON'S DISEASE, STRUCTURAL PROTEIN
2n0a:C (GLY73) to (ALA90) ATOMIC-RESOLUTION STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS | PROTEIN FIBRIL, AMYLOID, PARKINSON'S DISEASE, STRUCTURAL PROTEIN
2n0a:E (GLY73) to (ALA90) ATOMIC-RESOLUTION STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS | PROTEIN FIBRIL, AMYLOID, PARKINSON'S DISEASE, STRUCTURAL PROTEIN
2n0a:F (GLY73) to (ALA90) ATOMIC-RESOLUTION STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS | PROTEIN FIBRIL, AMYLOID, PARKINSON'S DISEASE, STRUCTURAL PROTEIN
2n0a:G (GLY73) to (ALA90) ATOMIC-RESOLUTION STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS | PROTEIN FIBRIL, AMYLOID, PARKINSON'S DISEASE, STRUCTURAL PROTEIN
2n0a:H (GLY73) to (ALA90) ATOMIC-RESOLUTION STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS | PROTEIN FIBRIL, AMYLOID, PARKINSON'S DISEASE, STRUCTURAL PROTEIN
2n0a:I (GLY73) to (ALA90) ATOMIC-RESOLUTION STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS | PROTEIN FIBRIL, AMYLOID, PARKINSON'S DISEASE, STRUCTURAL PROTEIN
2n0a:J (GLY73) to (ALA90) ATOMIC-RESOLUTION STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS | PROTEIN FIBRIL, AMYLOID, PARKINSON'S DISEASE, STRUCTURAL PROTEIN
1kzl:A (GLY138) to (ILE162) RIBOFLAVIN SYNTHASE FROM S.POMBE BOUND TO CARBOXYETHYLLUMAZINE | BIOSYNTHESIS OF RIBOFLAVIN, RIBOFLAVIN SYNTHASE, X-RAY STRUCTURE, SCHIZOSACCHAROMYCES POMBE, LIGAND BINDING, TRANSFERASE
2npf:A (PRO559) to (PRO592) STRUCTURE OF EEF2 IN COMPLEX WITH MORINIAFUNGIN | PROTEIN-INHIBITOR COMPLEX, G-PROTEIN, TRANSLATION
2npf:B (PRO559) to (PRO592) STRUCTURE OF EEF2 IN COMPLEX WITH MORINIAFUNGIN | PROTEIN-INHIBITOR COMPLEX, G-PROTEIN, TRANSLATION
3jr1:A (LYS187) to (ASN211) CRYSTAL STRUCTURE OF PUTATIVE FRUCTOSAMINE-3-KINASE (YP_719053.1) FROM HAEMOPHILUS SOMNUS 129PT AT 2.32 A RESOLUTION | YP_719053.1, PUTATIVE FRUCTOSAMINE-3-KINASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, FRUCTOSAMINE KINASE, TRANSFERASE
2ns2:B (SER201) to (ASP232) CRYSTAL STRUCTURE OF SPINDLIN1 | BETA BARREL, REPEAT DOMAINS, CELL CYCLE
4o5h:B (MET25) to (GLU59) X-RAY CRYSTAL STRUCTURE OF A PUTATIVE PHENYLACETALDEHYDE DEHYDROGENASE FROM BURKHOLDERIA CENOCEPACIA | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, PHENYLACETALDEHYDE DEHYDROGENASE, OXIDOREDUCTASE
2nu3:E (GLY196) to (GLN229) ACCOMMODATION OF POSITIVELY-CHARGED RESIDUES IN A HYDROPHOBIC SPECIFICITY POCKET: CRYSTAL STRUCTURES OF SGPB IN COMPLEX WITH OMTKY3 VARIANTS LYS18I AND ARG18I | ENZYME-INHIBITOR COMPLEX, CHARGED P1 RESIDUE, HYDROLASE
2nu4:E (GLY196) to (GLN229) ACCOMMODATION OF POSITIVELY-CHARGED RESIDUES IN A HYDROPHOBIC SPECIFICITY POCKET: CRYSTAL STRUCTURES OF SGPB IN COMPLEX WITH OMTKY3 VARIANTS LYS18I AND ARG18I | ENZYME-INHIBITOR COMPLEX, CHARGED P1 RESIDUE, HYDROLASE
4a1t:A (GLY140) to (VAL170) CO-COMPLEX OF THE OF NS3-4A PROTEASE WITH THE INHIBITORY PEPTIDE CP5-46-A (IN-HOUSE DATA) | HYDROLASE-PEPTIDE COMPLEX, UNMODIFIED INHIBITORY PEPTIDES
4a1t:B (GLY140) to (VAL170) CO-COMPLEX OF THE OF NS3-4A PROTEASE WITH THE INHIBITORY PEPTIDE CP5-46-A (IN-HOUSE DATA) | HYDROLASE-PEPTIDE COMPLEX, UNMODIFIED INHIBITORY PEPTIDES
4a1v:A (GLY140) to (VAL170) CO-COMPLEX STRUCTURE OF NS3-4A PROTEASE WITH THE OPTIMIZED INHIBITORY PEPTIDE CP5-46A-4D5E | HYDROLASE-PEPTIDE COMPLEX
4a1v:B (GLY140) to (VAL170) CO-COMPLEX STRUCTURE OF NS3-4A PROTEASE WITH THE OPTIMIZED INHIBITORY PEPTIDE CP5-46A-4D5E | HYDROLASE-PEPTIDE COMPLEX
4a1x:A (GLY140) to (VAL170) CO-COMPLEX STRUCTURE OF NS3-4A PROTEASE WITH THE INHIBITORY PEPTIDE CP5-46-A (SYNCHROTRON DATA) | HYDROLASE-PEPTIDE COMPLEX, UNMODIFIED INHIBITORY PEPTIDES
2nvy:B (GLY902) to (LEU941) RNA POLYMERASE II FORM II IN 150 MM MN+2 | TRANSCRIPTION, MRNA, MULTIPROTEIN COMPLEX, MOLECULAR MACHINE, DNA
2nvy:B (THR944) to (PRO974) RNA POLYMERASE II FORM II IN 150 MM MN+2 | TRANSCRIPTION, MRNA, MULTIPROTEIN COMPLEX, MOLECULAR MACHINE, DNA
2yuy:A (LYS10) to (ILE86) SOLUTION STRUCTURE OF PDZ DOMAIN OF RHO GTPASE ACTIVATING PROTEIN 21 | PDZ DOMAIN, RHO GTPASE ACTIVATING PROTEIN 21, NMR, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, SIGNALING PROTEIN
3k1f:B (VAL903) to (LEU941) CRYSTAL STRUCTURE OF RNA POLYMERASE II IN COMPLEX WITH TFIIB | RNA POLYMERASE II, TFIIB, TRANSCRIPTION FACTOR, TRANSCRIPTION INITIATION, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, METAL-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSCRIPTION, TRANSFERASE, ZINC-FINGER, DNA DAMAGE, DNA REPAIR, MRNA PROCESSING, INITIATION FACTOR
1lhg:H (ARG206) to (THR229) HUMAN ALPHA-THROMBIN COMPLEXED WITH AC-(D)PHE-PRO- BOROORNITHINE-OH | BLOOD COAGULATION, PLASMA, CALCIUM-BINDING, GLYCOPROTEIN, DUPLICATION, VITAMIN K, ZYMOGEN, GAMMA-CARBOXYGLUTAMIC ACID, ACUTE PHASE, LIVER, HYDROLASE, SERINE PROTEASE, KRINGLE, SIGNAL, DISEASE MUTATION, COMPLEX (SERINE PROTEASE/INHIBITOR)
3k2w:D (LYS11) to (PRO43) CRYSTAL STRUCTURE OF BETAINE-ALDEHYDE DEHYDROGENASE FROM PSEUDOALTEROMONAS ATLANTICA T6C | STRUCTURAL GENOMICS, PSI-2, ALDEHYDE DEHYDROGENASE, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, OXIDOREDUCTASE
3k2w:H (LYS11) to (PRO43) CRYSTAL STRUCTURE OF BETAINE-ALDEHYDE DEHYDROGENASE FROM PSEUDOALTEROMONAS ATLANTICA T6C | STRUCTURAL GENOMICS, PSI-2, ALDEHYDE DEHYDROGENASE, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, OXIDOREDUCTASE
2z1a:A (ASN140) to (THR173) CRYSTAL STRUCTURE OF 5'-NUCLEOTIDASE PRECURSOR FROM THERMUS THERMOPHILUS HB8 | NUCLEOTIDASE, METAL-BINDING, NUCLEOTIDE-BINDING, HYDROLASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2z1b:D (ASN30) to (VAL58) CRYSTAL STRUCTURE OF 5-AMINOLEVULINIC ACID DEHYDRATASE (ALAD) FROM MUS MUSCULS | STRUCTURE GENOMICS, CONSERVED HYPOTHETICAL PROTEIN, LYASE, PORPHYRIN BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2nzh:A (LYS62) to (VAL82) CRYSTAL STRUCTURE OF A SECRETION CHAPERONE CSAA FROM BACILLUS SUBTILIS IN THE SPACE GROUP P 4 21 2 | BETA BARREL, OLIGONUCLEOTIDE/OLIGOSACCHARIDE BINDING FOLD, HOMODIMER, CHAPERONE
2nzo:B (LYS62) to (VAL82) CRYSTAL STRUCTURE OF A SECRETION CHAPERONE CSAA FROM BACILLUS SUBTILIS IN THE SPACE GROUP P 32 2 1 | BETA BARREL, OLIGONUCLEOTIDE/OLIGOSACCHARIDE BINDING FOLD, OB FOLD, HOMODIMER, CHAPERONE
2nzo:D (VAL64) to (VAL82) CRYSTAL STRUCTURE OF A SECRETION CHAPERONE CSAA FROM BACILLUS SUBTILIS IN THE SPACE GROUP P 32 2 1 | BETA BARREL, OLIGONUCLEOTIDE/OLIGOSACCHARIDE BINDING FOLD, OB FOLD, HOMODIMER, CHAPERONE
1lla:A (THR482) to (HIS503) CRYSTAL STRUCTURE OF DEOXYGENATED LIMULUS POLYPHEMUS SUBUNIT II HEMOCYANIN AT 2.18 ANGSTROMS RESOLUTION: CLUES FOR A MECHANISM FOR ALLOSTERIC REGULATION | OXYGEN TRANSPORT
4ogx:A (VAL444) to (LYS488) CRYSTAL STRUCTURE OF FAB DX-2930 IN COMPLEX WITH HUMAN PLASMA KALLIKREIN AT 2.4 ANGSTROM RESOLUTION | FAB, ANTIBODY, KALLIKREIN, BLOOD, PLASMA, PLASMA KALLIKREIN- MEDIATED EDEMA, ACUTE HEREDITARY ANGIOEDEMA, HAE, HMWK, SERPIN C1-INHIBITOR, C1-INH, HEREDITARY ANGIOEDEMA, HAW, BRADYKININ, FLETCHER FACTOR, KININOGENIN, SERINE PROTEASE, EDEMA, HYDROLASE-ANTIBODY COMPLEX
4ogy:A (VAL444) to (LYS488) CRYSTAL STRUCTURE OF FAB DX-2930 IN COMPLEX WITH HUMAN PLASMA KALLIKREIN AT 2.1 ANGSTROM RESOLUTION | FAB, ANTIBODY, KALLIKREIN, BLOOD, PLASMA, PLASMA KALLIKREIN- MEDIATED EDEMA, ACUTE HEREDITARY ANGIOEDEMA, HAE, HMWK, SERPIN C1-INHIBITOR, C1-INH, HEREDITARY ANGIOEDEMA, HAW, BRADYKININ, FLETCHER FACTOR, KININOGENIN, SERINE PROTEASE, EDEMA, HYDROLASE-ANTIBODY COMPLEX
5cmx:H (ARG206) to (THR229) X-RAY STRUCTURE OF THE COMPLEX BETWEEN HUMAN ALPHA THROMBIN AND A DUPLEX/QUADRUPLEX 31-MER DNA APTAMER | DNA APTAMER, DUPLEX/G-QUADRUPLEX FOLD, THROMBIN, EXOSITE I, HYDROLASE
2z7f:E (SER197) to (ALA229) CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN NEUTROPHIL ELASTASE WITH 1/2SLPI | SERINE PROTEASE, SERINE PROTEASE INHIBITOR, DISEASE MUTATION, GLYCOPROTEIN, HYDROLASE, ZYMOGEN, SECRETED, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2z9i:A (GLY170) to (ILE208) CRYSTAL STRUCTURE OF RV0983 FROM MYCOBACTERIUM TUBERCULOSIS- PROTEOLYTICALLY ACTIVE FORM | SERINE PROTEASE, HTRA, HYDROLASE
1xkv:A (GLY211) to (GLY232) CRYSTAL STRUCTURE OF ATP-DEPENDENT PHOSPHOENOLPYRUVATE CARBOXYKINASE FROM THERMUS THERMOPHILUS HB8 | PHOSPHOENOLPYRUVATE CARBOXYKINASE, ADENOSINE TRIPHOSPHATE, THERMUS THERMOPHILUS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, LYASE
1xkw:A (ALA542) to (SER568) PYOCHELIN OUTER MEMBRANE RECEPTOR FPTA FROM PSEUDOMONAS AERUGINOSA | TONB DEPENDENT RECEPTOR, MEMBRANE PROTEIN
1lvb:A (SER153) to (THR180) CATALYTICALLY INACTIVE TOBACCO ETCH VIRUS PROTEASE COMPLEXED WITH SUBSTRATE | BETA BARREL, PROTEIN-PEPTIDE COMPLEX, CHYMOTRYPSIN-LIKE CYSTEIN PROTEASE, VIRAL PROTEIN
1lvb:B (SER153) to (THR180) CATALYTICALLY INACTIVE TOBACCO ETCH VIRUS PROTEASE COMPLEXED WITH SUBSTRATE | BETA BARREL, PROTEIN-PEPTIDE COMPLEX, CHYMOTRYPSIN-LIKE CYSTEIN PROTEASE, VIRAL PROTEIN
1lvo:A (ASN64) to (LYS89) STRUCTURE OF CORONAVIRUS MAIN PROTEINASE REVEALS COMBINATION OF A CHYMOTRYPSIN FOLD WITH AN EXTRA ALPHA- HELICAL DOMAIN | 3C LIKE, CORONA, PROTEINASE, CHYMOTRYPSIN, CYSTEINE HISTIDINE DYAD, BETA BARREL, HYDROLASE
4ojl:A (CYS697) to (LEU720) CRYSTAL STRUCTURE OF PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 IN COMPLEX WITH GLUCOSE | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
4ojl:C (CYS697) to (LEU720) CRYSTAL STRUCTURE OF PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 IN COMPLEX WITH GLUCOSE | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
4ojo:A (CYS697) to (LEU720) CRYSTAL STRUCTURE OF PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 IN COMPLEX WITH LACTOSE | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
4ojo:C (CYS697) to (LEU720) CRYSTAL STRUCTURE OF PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 IN COMPLEX WITH LACTOSE | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
4ojz:B (PHE560) to (ASN585) CRYSTAL STRUCTURE OF ALG17C MUTANT Y258A COMPLEXED WITH ALGINATE TRISACCHARIDE | ALGINATE LYASE, LYASE
3k7a:B (GLY902) to (LEU941) CRYSTAL STRUCTURE OF AN RNA POLYMERASE II-TFIIB COMPLEX | RNA POLYMERASE II, TFIIB, TRANSCRIPTION, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, METAL-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, ZINC- FINGER, DNA DAMAGE, DNA REPAIR, TRANSCRIPTION REGULATION
1xmn:F (ARG206) to (THR229) CRYSTAL STRUCTURE OF THROMBIN BOUND TO HEPARIN | BLOOD CLOTTING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ok2:A (PHE560) to (ASN585) CRYSTAL STRUCTURE OF ALG17C MUTANT Y258A | ALGINATE LYASE, LYASE
4ok4:A (PHE560) to (ASN585) CRYSTAL STRUCTURE OF ALG17C MUTANT H202L | ALGINATE LYASE, LYASE
4ok4:B (PHE560) to (ASN585) CRYSTAL STRUCTURE OF ALG17C MUTANT H202L | ALGINATE LYASE, LYASE
4olw:G (GLY263) to (ASN289) CRYSTAL STRUCTURE OF ANTIBODY VRC07-G54H IN COMPLEX WITH CLADE A/E 93TH057 HIV-1 GP120 CORE | VRC07 ANTIBODY, PASSIVE TRANSFER, NEUTRALIZATION, IN VIVO PROTECTION, AUTOREACTIVITY, LENTIVIRAL INFECTION, ENHANCED POTENCY, HIV-1 GP120, VRC07-G54H, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
4olz:G (GLY263) to (ASN289) CRYSTAL STRUCTURE OF ANTIBODY VRC07-G54W IN COMPLEX WITH CLADE A/E 93TH057 HIV-1 GP120 CORE | VRC07 ANTIBODY, PASSIVE TRANSFER, NEUTRALIZATION, IN VIVO PROTECTION, AUTOREACTIVITY, LENTIVIRAL INFECTION, ENHANCED POTENCY, HIV-1 GP120, VRC07-G54W, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
4omo:B (GLU106) to (PRO133) CRYSTAL STRUCTURE OF THE C-SRC TYROSINE KINASE SH3 DOMAIN MUTANT Q128E | BETA-BARREL SANDWICH, KINASE, PROLINE RICH MOTIFS, TRANSFERASE
2zhs:A (THR59) to (GLU79) CRYSTAL STRUCTURE OF BACE1 AT PH 4.0 | PH 4.0, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
4onw:A (PRO61) to (ARG97) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF DAPE PROTEIN FROM V.CHOLEREA | DAPE, M20, AMINOPEPTIDASE, CSGID, STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, ZN BINDING, HYDROLASE
2zit:A (LEU554) to (PRO592) STRUCTURE OF THE EEF2-EXOA-NAD+ COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, TOXIN-SUBSTRATE COMPLEX, CYTOPLASM, GTP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PROTEIN BIOSYNTHESIS, RNA-BINDING, RRNA- BINDING, GLYCOSYLTRANSFERASE, NAD, TRANSFERASE, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
2zit:E (PRO559) to (PRO592) STRUCTURE OF THE EEF2-EXOA-NAD+ COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, TOXIN-SUBSTRATE COMPLEX, CYTOPLASM, GTP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PROTEIN BIOSYNTHESIS, RNA-BINDING, RRNA- BINDING, GLYCOSYLTRANSFERASE, NAD, TRANSFERASE, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
4a97:D (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH ZOPICLONE | TRANSPORT PROTEIN, CYS-LOOP RECEPTOR, GABA-A RECEPTOR, BENZODIAZEPINE
4a97:E (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH ZOPICLONE | TRANSPORT PROTEIN, CYS-LOOP RECEPTOR, GABA-A RECEPTOR, BENZODIAZEPINE
4a97:F (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH ZOPICLONE | TRANSPORT PROTEIN, CYS-LOOP RECEPTOR, GABA-A RECEPTOR, BENZODIAZEPINE
5cus:D (PHE560) to (PRO593) CRYSTAL STRUCTURE OF SERBB3-FAB3379 COMPLEX | ERBB3, ANTIBODY, TRANSFERASE
4op7:A (GLY428) to (LEU452) CRYSTAL STRUCTURE OF P DOMAIN FROM NOROVIRUS STRAIN NSW0514 IN COMPLEX WITH HBGA TYPE B (TRIGLYCAN) | NOROVIRUS, VIRAL CAPSID PROTEIN, HISTO BLOOD GROUP ANTIGEN (HBGA), PROTRUDING DOMAIN, VIRAL PROTEIN
4op7:B (GLY428) to (LEU452) CRYSTAL STRUCTURE OF P DOMAIN FROM NOROVIRUS STRAIN NSW0514 IN COMPLEX WITH HBGA TYPE B (TRIGLYCAN) | NOROVIRUS, VIRAL CAPSID PROTEIN, HISTO BLOOD GROUP ANTIGEN (HBGA), PROTRUDING DOMAIN, VIRAL PROTEIN
5cwe:A (TYR285) to (GLU301) STRUCTURE OF CYP107L2 FROM STREPTOMYCES AVERMITILIS WITH LAURIC ACID | STREPTOMYCES AVERMITILIS, P450, CYP107L2, LAURIC ACID, OXIDOREDUCTASE
3kee:A (GLY140) to (VAL170) HCV NS3/NS4A COMPLEXED WITH NON-COVALENT MACROCYCLIC COMPOUND TMC435 | HCV, NS3, NS4A, MACROCYCLE, NONCOVALENT, TMC435, HYDROLASE
3kee:B (GLY140) to (VAL170) HCV NS3/NS4A COMPLEXED WITH NON-COVALENT MACROCYCLIC COMPOUND TMC435 | HCV, NS3, NS4A, MACROCYCLE, NONCOVALENT, TMC435, HYDROLASE
3kee:C (GLY140) to (VAL170) HCV NS3/NS4A COMPLEXED WITH NON-COVALENT MACROCYCLIC COMPOUND TMC435 | HCV, NS3, NS4A, MACROCYCLE, NONCOVALENT, TMC435, HYDROLASE
3kee:D (GLY140) to (VAL170) HCV NS3/NS4A COMPLEXED WITH NON-COVALENT MACROCYCLIC COMPOUND TMC435 | HCV, NS3, NS4A, MACROCYCLE, NONCOVALENT, TMC435, HYDROLASE
3kf2:A (GLY140) to (ILE170) THE HCV NS3/NS4A PROTEASE APO STRUCTURE | HCV, NS3, PROTEASE, APO, HYDROLASE
3kf2:B (GLY140) to (ILE170) THE HCV NS3/NS4A PROTEASE APO STRUCTURE | HCV, NS3, PROTEASE, APO, HYDROLASE
3kfd:G (LYS42) to (VAL77) TERNARY COMPLEX OF TGF-B1 REVEALS ISOFORM-SPECIFIC LIGAND RECOGNITION AND RECEPTOR RECRUITMENT IN THE SUPERFAMILY | TGF-BETA, TGF-B1, TGF-BETA RECEPTOR TYPE-1, TGF-BETA RECEPTOR TYPE-2, TBRII, TBRI, GROWTH FACTOR, RECEPTOR, SERINE/THREONINE-PROTEIN KINASE, CYTOKINE-CYTOKINE RECEPTOR COMPLEX
3kfd:H (LYS42) to (VAL77) TERNARY COMPLEX OF TGF-B1 REVEALS ISOFORM-SPECIFIC LIGAND RECOGNITION AND RECEPTOR RECRUITMENT IN THE SUPERFAMILY | TGF-BETA, TGF-B1, TGF-BETA RECEPTOR TYPE-1, TGF-BETA RECEPTOR TYPE-2, TBRII, TBRI, GROWTH FACTOR, RECEPTOR, SERINE/THREONINE-PROTEIN KINASE, CYTOKINE-CYTOKINE RECEPTOR COMPLEX
4os6:A (GLY197) to (THR229) CRYSTAL STRUCTURE OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR (UPA) COMPLEXED WITH BICYCLIC PEPTIDE UK604 (BICYCLIC 2) | BICYCLIC PEPTIDE, INHIBITOR, PROTEASE, DISULFIDE BRIDGES, CYCLIZATION, EXTRACELLULAR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ose:A (ILE3) to (GLN22) X-RAY CRYSTAL STRUCTURE OF A PUTATIVE HYDROLASE FROM RICKETTSIA TYPHI | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, HYDROLASE
2zp0:H (THR206) to (THR229) HUMAN FACTOR VIIA-TISSUE FACTOR COMPLEXED WITH BENZYLSULFONAMIDE-D- ILE-GLN-P-AMINOBENZAMIDINE | SERINE PROTEASE, BLOOD COAGULATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISEASE MUTATION, EGF-LIKE DOMAIN, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, HYDROXYLATION, PROTEASE, ZYMOGEN, LIPOPROTEIN, MEMBRANE, PALMITATE, TRANSMEMBRANE, HYDROLASE-BLOOD CLOTTING COMPLEX
1xxd:A (VAL202) to (THR229) CRYSTAL STRUCTURE OF THE FXIA CATALYTIC DOMAIN IN COMPLEX WITH MUTATED ECOTIN | FXIA; CATALYTIC DOMAIN; SERINE PROTEIN; ECOTIN, BLOOD CLOTTING/HYDROLASE INHIBITOR COMPLEX
1xxd:B (GLY197) to (THR229) CRYSTAL STRUCTURE OF THE FXIA CATALYTIC DOMAIN IN COMPLEX WITH MUTATED ECOTIN | FXIA; CATALYTIC DOMAIN; SERINE PROTEIN; ECOTIN, BLOOD CLOTTING/HYDROLASE INHIBITOR COMPLEX
3khv:A (GLY197) to (THR229) CRYSTAL STRUCTURES OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR IN COMPLEX WITH 4-(AMINOMETHYL) BENZOIC ACID AND 4- (AMINOMETHYL-PHENYL)-METHANOL | PROTEIN-LIGAND COMPLEX, DISULFIDE BOND, FIBRINOLYSIS, HYDROLASE, PLASMINOGEN ACTIVATION, SERINE PROTEASE
3khz:A (ASN76) to (ARG111) CRYSTAL STRUCTURE OF R350A MUTANT OF STAPHYLOCOCCUS AUREUS METALLOPEPTIDASE (SAPEP/DAPE) IN THE APO-FORM | R350A MUTANT-DIPEPTIDASE, DAPE, METALLOPEPTIDASE, DIPEPTIDASE, HYDROLASE, METAL-BINDING, METALLOPROTEASE, PROTEASE
3khz:B (ASN76) to (ARG111) CRYSTAL STRUCTURE OF R350A MUTANT OF STAPHYLOCOCCUS AUREUS METALLOPEPTIDASE (SAPEP/DAPE) IN THE APO-FORM | R350A MUTANT-DIPEPTIDASE, DAPE, METALLOPEPTIDASE, DIPEPTIDASE, HYDROLASE, METAL-BINDING, METALLOPROTEASE, PROTEASE
4abg:A (GLY197) to (THR229) FRAGMENTS BOUND TO BOVINE TRYPSIN FOR THE SAMPL CHALLENGE | HYDROLASE, FRAGMENT SCREENING, MODELLING
1mab:A (GLU51) to (VAL74) RAT LIVER F1-ATPASE | ATP SYNTHASE, FOF1-ATPASE, OXIDATIVE PHOSPHORYLATION, MITOCHONDRIA, HYDROLASE
1max:A (GLY197) to (THR229) BETA-TRYPSIN PHOSPHONATE INHIBITED | HYDROLASE, SERINE PROTEASE, DIGESTION, PANCREAS, ZYMOGEN, HYDROLASE (SERINE PROTEASE)
1mbm:D (SER122) to (THR147) NSP4 PROTEINASE FROM EQUINE ARTERITIS VIRUS | SERINE PROTEINASE, CHYMOTRYPSIN-LIKE PROTEINASE, COLLAPSED OXYANION HOLE, TRANSFERASE
3klk:A (ASN1648) to (ASP1675) CRYSTAL STRUCTURE OF LACTOBACILLUS REUTERI N-TERMINALLY TRUNCATED GLUCANSUCRASE GTF180 IN TRICLINIC APO- FORM | NATIVE FORM, OPEN CONFORMATION, MULTIDOMAIN PROTEIN, GLYCOSYLTRANSFERASE, TRANSFERASE
4afq:A (GLY184) to (THR210) HUMAN CHYMASE - FYNOMER COMPLEX | HYDROLASE-DE NOVO PROTEIN COMPLEX, INHIBITOR, SERINE PROTEASE
4afq:B (GLY184) to (THR210) HUMAN CHYMASE - FYNOMER COMPLEX | HYDROLASE-DE NOVO PROTEIN COMPLEX, INHIBITOR, SERINE PROTEASE
4afu:B (GLY184) to (THR210) HUMAN CHYMASE - FYNOMER COMPLEX | HYDROLASE-DE NOVO PROTEIN COMPLEX, INHIBITOR, SERINE PROTEASE
4p1v:D (GLY301) to (ASN357) STRUCTURE OF THE P DOMAIN FROM A GI.7 NOROVIRUS VARIANT IN COMPLEX WITH H-TYPE 2 HBGA | P DOMAIN, CAPSID PROTEIN, NOROVIRUS, HBGA, H-TYPE2, SECRETOR, VIRAL PROTEIN
4p25:A (GLY301) to (GLN356) STRUCTURE OF THE P DOMAIN FROM A GI.7 NOROVIRUS VARIANT IN COMPLEX WITH LEY HBGA. | P DOMAIN, CAPSID PROTEIN, NOROVIRUS, HBGA, LEY, LEWIS HBGA, VIRAL PROTEIN
4p26:B (GLY301) to (GLN356) STRUCTURE OF THE P DOMAIN FROM A GI.7 NOROVIRUS VARIANT IN COMPLEX WITH A-TYPE 2 HBGA | P DOMAIN, CAPSID PROTEIN, NOROVIRUS, HBGA, A TYPE 2, TYPE 2 HBGA, SECRETOR, VIRAL PROTEIN
4p2n:C (GLY301) to (GLN356) STRUCTURE OF THE P DOMAIN FROM A GI.7 NOROVIRUS VARIANT IN COMPLEX WITH LEX HBGA | P DOMAIN, CAPSID PROTEIN, NOROVIRUS, HBGA, LEY, LEWIS HBGA, NONSECRETOR, VIRAL PROTEIN
3kmc:B (LEU348) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TACE WITH TARTRATE-BASED INHIBITOR | A DISINTEGRIN AND METALLOPROTEINASE DOMAIN 17, TNF-ALPHA-CONVERTING ENZYME, TNF-ALPHA CONVERTASE, SNAKE VENOM-LIKE PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, GLYCOPROTEIN, MEMBRANE, METAL-BINDING, METALLOPROTEASE, NOTCH SIGNALING PATHWAY, PHOSPHOPROTEIN, PROTEASE, ZYMOGEN, HYDROLASE
3kn2:A (GLY140) to (ILE170) HCV NS3 PROTEASE DOMAIN WITH KETOAMIDE INHIBITOR | HEPATITIS C VIRUS, NS3 PROTEASE DOMAIN, SERINE PROTEASE, KETOAMIDE INHIBITOR, ATP-BINDING, CAPSID PROTEIN, ENVELOPE PROTEIN, HELICASE, HOST MEMBRANE, HYDROLASE, MEMBRANE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, VIRION
3kn2:C (GLY140) to (ILE170) HCV NS3 PROTEASE DOMAIN WITH KETOAMIDE INHIBITOR | HEPATITIS C VIRUS, NS3 PROTEASE DOMAIN, SERINE PROTEASE, KETOAMIDE INHIBITOR, ATP-BINDING, CAPSID PROTEIN, ENVELOPE PROTEIN, HELICASE, HOST MEMBRANE, HYDROLASE, MEMBRANE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, VIRION
3knx:A (GLY140) to (ILE170) HCV NS3 PROTEASE DOMAIN WITH P1-P3 MACROCYCLIC KETOAMIDE INHIBITOR | HEPATITIS C VIRUS, NS3 PROTEASE DOMAIN, SERINE PROTEASE, MACROCYCLIC KETOAMIDE INHIBITOR, ATP-BINDING, ENVELOPE PROTEIN, HELICASE, HYDROLASE, MEMBRANE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, VIRAL PROTEIN
3knx:C (GLY140) to (ILE170) HCV NS3 PROTEASE DOMAIN WITH P1-P3 MACROCYCLIC KETOAMIDE INHIBITOR | HEPATITIS C VIRUS, NS3 PROTEASE DOMAIN, SERINE PROTEASE, MACROCYCLIC KETOAMIDE INHIBITOR, ATP-BINDING, ENVELOPE PROTEIN, HELICASE, HYDROLASE, MEMBRANE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, VIRAL PROTEIN
3kow:D (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE BACKSOAKED COMPLEX | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), BACKSOAKED, METAL BINDING PROTEIN
3kox:A (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE IN COMPLEX WITH 2,4- DIAMINOBUTYRATE (ANAEROBIC) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), 2, 4-DIAMINOBUTYRATE (DAB) COMPLEX, ANAEROBIC, METAL BINDING PROTEIN
3kox:B (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE IN COMPLEX WITH 2,4- DIAMINOBUTYRATE (ANAEROBIC) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), 2, 4-DIAMINOBUTYRATE (DAB) COMPLEX, ANAEROBIC, METAL BINDING PROTEIN
3kox:C (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE IN COMPLEX WITH 2,4- DIAMINOBUTYRATE (ANAEROBIC) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), 2, 4-DIAMINOBUTYRATE (DAB) COMPLEX, ANAEROBIC, METAL BINDING PROTEIN
3kox:D (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE IN COMPLEX WITH 2,4- DIAMINOBUTYRATE (ANAEROBIC) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), 2, 4-DIAMINOBUTYRATE (DAB) COMPLEX, ANAEROBIC, METAL BINDING PROTEIN
1y8q:C (TYR161) to (CYS214) SUMO E1 ACTIVATING ENZYME SAE1-SAE2-MG-ATP COMPLEX | SUMO; E1; HETERODIMER; ACTIVATING ENZYME; UBL, LIGASE
3koy:A (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE IN COMPLEX WITH ORNITHINE (AEROBIC) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), ORNITHINE COMPLEX, AEROBIC, METAL BINDING PROTEIN
3koy:B (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE IN COMPLEX WITH ORNITHINE (AEROBIC) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), ORNITHINE COMPLEX, AEROBIC, METAL BINDING PROTEIN
3koy:C (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE IN COMPLEX WITH ORNITHINE (AEROBIC) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), ORNITHINE COMPLEX, AEROBIC, METAL BINDING PROTEIN
3koy:D (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE IN COMPLEX WITH ORNITHINE (AEROBIC) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), ORNITHINE COMPLEX, AEROBIC, METAL BINDING PROTEIN
3koz:A (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE IN COMPLEX WITH ORNITHINE (ANAEROBIC) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), ORNITHINE COMPLEX, ANAEROBIC, METAL BINDING PROTEIN
3koz:C (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE IN COMPLEX WITH ORNITHINE (ANAEROBIC) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), ORNITHINE COMPLEX, ANAEROBIC, METAL BINDING PROTEIN
3koz:D (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE IN COMPLEX WITH ORNITHINE (ANAEROBIC) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), ORNITHINE COMPLEX, ANAEROBIC, METAL BINDING PROTEIN
3kp0:A (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE IN COMPLEX WITH 2,4- DIAMINOBUTYRATE (DAB) (AEROBIC) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), DAB COMPLEX, AEROBIC, METAL BINDING PROTEIN
3kp0:B (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE IN COMPLEX WITH 2,4- DIAMINOBUTYRATE (DAB) (AEROBIC) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), DAB COMPLEX, AEROBIC, METAL BINDING PROTEIN
3kp1:A (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE (RESTING STATE) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), METAL BINDING PROTEIN
3kp1:D (ASP103) to (THR133) CRYSTAL STRUCTURE OF ORNITHINE 4,5 AMINOMUTASE (RESTING STATE) | D-ORNITHINE 4, 5 AMINOMUTASE (OAM), METAL BINDING PROTEIN
3a35:A (ASP136) to (ASN158) CRYSTAL STRUCTURE OF LUMP COMPLEXED WITH RIBOFLAVIN | LUMINOUS BACTERIA, LUMAZINE PROTEIN, HOMOLOGUE OF RIBOFLAVIN SYNTHASE, LUMINESCENT PROTEIN
3a35:B (ASP136) to (ASN158) CRYSTAL STRUCTURE OF LUMP COMPLEXED WITH RIBOFLAVIN | LUMINOUS BACTERIA, LUMAZINE PROTEIN, HOMOLOGUE OF RIBOFLAVIN SYNTHASE, LUMINESCENT PROTEIN
3a3b:B (ASP136) to (ASN158) CRYSTAL STRUCTURE OF LUMP COMPLEXED WITH FLAVIN MONONUCLEOTIDE | LUMINOUS BACTERIA, LUMAZINE PROTEIN, FLAVIN MONONUCLEOTIDE, LUMINESCENT PROTEIN
3a3b:A (ASP136) to (ASN158) CRYSTAL STRUCTURE OF LUMP COMPLEXED WITH FLAVIN MONONUCLEOTIDE | LUMINOUS BACTERIA, LUMAZINE PROTEIN, FLAVIN MONONUCLEOTIDE, LUMINESCENT PROTEIN
3krj:A (ASN773) to (ILE794) CFMS TYROSINE KINASE IN COMPLEX WITH 4-CYANO-1H-IMIDAZOLE-2-CARBOXYLIC ACID (2-CYCLOHEX-1-ENYL-4-PIPERIDIN-4-YL-PHENYL)-AMIDE | KINASE, INHIBITOR, CHIMERA, ATP-BINDING, DISULFIDE BOND, GLYCOPROTEIN, IMMUNOGLOBULIN DOMAIN, MEMBRANE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PROTO-ONCOGENE, RECEPTOR, TRANSFERASE, TRANSMEMBRANE, TYROSINE-PROTEIN KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4pb3:B (GLN300) to (ALA325) D-THREO-3-HYDROXYASPARTATE DEHYDRATASE H351A MUTANT | PLP ENZYME, DEHYDRATASE, METALLOPROTEIN, LYASE
3a5c:A (GLY164) to (MET183) INTER-SUBUNIT INTERACTION AND QUATERNARY REARRANGEMENT DEFINED BY THE CENTRAL STALK OF PROKARYOTIC V1-ATPASE | V-ATPASE, ASYMMETRIC, CRYSTAL STRUCTURE, ROTATION, VACUOLAR TYPE, HYDROLASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
3a5c:B (GLY164) to (MET183) INTER-SUBUNIT INTERACTION AND QUATERNARY REARRANGEMENT DEFINED BY THE CENTRAL STALK OF PROKARYOTIC V1-ATPASE | V-ATPASE, ASYMMETRIC, CRYSTAL STRUCTURE, ROTATION, VACUOLAR TYPE, HYDROLASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
3a5c:C (GLY164) to (MET183) INTER-SUBUNIT INTERACTION AND QUATERNARY REARRANGEMENT DEFINED BY THE CENTRAL STALK OF PROKARYOTIC V1-ATPASE | V-ATPASE, ASYMMETRIC, CRYSTAL STRUCTURE, ROTATION, VACUOLAR TYPE, HYDROLASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
3a5c:I (GLY164) to (MET183) INTER-SUBUNIT INTERACTION AND QUATERNARY REARRANGEMENT DEFINED BY THE CENTRAL STALK OF PROKARYOTIC V1-ATPASE | V-ATPASE, ASYMMETRIC, CRYSTAL STRUCTURE, ROTATION, VACUOLAR TYPE, HYDROLASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
3a5c:J (GLY164) to (MET183) INTER-SUBUNIT INTERACTION AND QUATERNARY REARRANGEMENT DEFINED BY THE CENTRAL STALK OF PROKARYOTIC V1-ATPASE | V-ATPASE, ASYMMETRIC, CRYSTAL STRUCTURE, ROTATION, VACUOLAR TYPE, HYDROLASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
3a5c:K (GLY164) to (MET183) INTER-SUBUNIT INTERACTION AND QUATERNARY REARRANGEMENT DEFINED BY THE CENTRAL STALK OF PROKARYOTIC V1-ATPASE | V-ATPASE, ASYMMETRIC, CRYSTAL STRUCTURE, ROTATION, VACUOLAR TYPE, HYDROLASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
1n0u:A (PRO559) to (PRO592) CRYSTAL STRUCTURE OF YEAST ELONGATION FACTOR 2 IN COMPLEX WITH SORDARIN | G-PROTEIN, CIS-PROLINE, TRANSLATION
1n0v:D (LEU554) to (PRO592) CRYSTAL STRUCTURE OF ELONGATION FACTOR 2 | G-PROTEIN CIS-PROLINE, TRANSLATION
1n1l:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX WITH COVALENTLY BOUND INHIBITOR (GW472467X) | VIRAL PROTEIN, SERINE PROTEASE, NONSTRUCTURAL PROTEINS, COFACTOR PEPTIDE, HELICASE, INHIBITOR
1n1l:B (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX WITH COVALENTLY BOUND INHIBITOR (GW472467X) | VIRAL PROTEIN, SERINE PROTEASE, NONSTRUCTURAL PROTEINS, COFACTOR PEPTIDE, HELICASE, INHIBITOR
3kyc:A (TYR161) to (CYS214) HUMAN SUMO E1 COMPLEX WITH A SUMO1-AMP MIMIC | E1, SUMO, UBIQUITIN, THIOESTER, ADENYLATION, INHIBITOR, ACYL-ADENYLATE INTERMEDIATE, ACETYLATION, LIGASE, NUCLEUS, PHOSPHOPROTEIN, UBL CONJUGATION PATHWAY, ATP-BINDING, NUCLEOTIDE-BINDING, POLYMORPHISM, CYTOPLASM, ISOPEPTIDE BOND, MEMBRANE
1ype:H (ARG206) to (THR229) THROMBIN INHIBITOR COMPLEX | THROMBIN, INHIBITOR COMPLEX, BARREL, 6 STRANDED BETA-SHEET, BLOOD CLOTTING-HYDROLASE INHIBITOR COMPLEX
1yph:E (ALA179) to (GLY211) HIGH RESOLUTION STRUCTURE OF BOVINE ALPHA-CHYMOTRYPSIN | SERINE PROTEASE, HYDROLASE
3l0k:A (LEU189) to (SER210) HUMAN OROTIDYL-5'-MONOPHOSPHATE DECARBOXYLASE IN COMPLEX WITH 6-ACETYL-UMP | DECARBOXYLASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS
3l0k:B (LEU189) to (SER210) HUMAN OROTIDYL-5'-MONOPHOSPHATE DECARBOXYLASE IN COMPLEX WITH 6-ACETYL-UMP | DECARBOXYLASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS
3l0v:A (LEU348) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TACE WITH THE FIRST HYDANTOIN INHIBITOR OCCUPYING THE S1' POCKET | METAL-BINDING, METALLOPROTEASE, NOTCH SIGNALING PATHWAY, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4pim:B (ARG249) to (ALA274) ERGOTHIONEINE-BIOSYNTHETIC METHYLTRANSFERASE EGTD, APO FORM | METHYLTRANSFERASE, ERGOTHIONEINE, HISTIDINE BETAINE, TRANSFERASE
4pip:B (ARG249) to (ALA274) ENGINEERED EGTD VARIANT EGTD-M252V,E282A IN COMPLEX WITH TRYPTOPHAN AND SAH | METHYLTRANSFERASE, ERGOTHIONEINE, HISTIDINE BETAINE, TRANSFERASE
3l3o:A (GLN258) to (SER281) STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) IN COMPLEX WITH HUMAN COMPLEMENT COMPONENT C3C | COMPLEMENT ALTERNATE PATHWAY, COMPLEMENT PATHWAY, CONVERSTASE, IMMUNE RESPONSE, INFLAMMATORY RESPONSE, INNATE IMMUNITY, SECRETED, VIRULENCE, IMMUNE EVASION, IMMUNE SYSTEM
3l3o:D (GLN258) to (SER281) STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) IN COMPLEX WITH HUMAN COMPLEMENT COMPONENT C3C | COMPLEMENT ALTERNATE PATHWAY, COMPLEMENT PATHWAY, CONVERSTASE, IMMUNE RESPONSE, INFLAMMATORY RESPONSE, INNATE IMMUNITY, SECRETED, VIRULENCE, IMMUNE EVASION, IMMUNE SYSTEM
1yrq:J (GLY314) to (TYR376) STRUCTURE OF THE READY OXIDIZED FORM OF [NIFE]-HYDROGENASE | NIB STATE, HYDROXIDE BRIDGE, OXIDOREDUCTASE
1ytm:A (GLY220) to (GLY242) CRYSTAL STRUCTURE OF PHOSPHOENOLPYRUVATE CARBOXYKINASE OF ANAEROBIOSPIRILLUM SUCCINICIPRODUCENS COMPLEXED WITH ATP, OXALATE, MAGNESIUM AND MANGANESE IONS | KINASE; DOMAIN CLOSURE; NUCLEOTIDE BINDING; PARALLEL BETA SHEET-LIKE HYDROGEN BOND, LYASE
1ytm:B (GLY1220) to (GLY1242) CRYSTAL STRUCTURE OF PHOSPHOENOLPYRUVATE CARBOXYKINASE OF ANAEROBIOSPIRILLUM SUCCINICIPRODUCENS COMPLEXED WITH ATP, OXALATE, MAGNESIUM AND MANGANESE IONS | KINASE; DOMAIN CLOSURE; NUCLEOTIDE BINDING; PARALLEL BETA SHEET-LIKE HYDROGEN BOND, LYASE
1ywh:E (GLY148) to (ASN172) CRYSTAL STRUCTURE OF UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR | UPAR, THREE-FINGER FOLD, PROTEIN-PEPTIDE COMPLEX, HYDROLASE RECEPTOR
1ywh:K (CYS147) to (CYS171) CRYSTAL STRUCTURE OF UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR | UPAR, THREE-FINGER FOLD, PROTEIN-PEPTIDE COMPLEX, HYDROLASE RECEPTOR
3l6p:A (SER187) to (ALA216) CRYSTAL STRUCTURE OF DENGUE VIRUS 1 NS2B/NS3 PROTEASE | VIRAL PROTEASE, SERINE PROTEASE, NS3 PROTEASE, NS2B COFACTOR, VIRAL PROTEIN, HYDROLASE
1yyl:G (GLY263) to (ASN289) CRYSTAL STRUCTURE OF CD4M33, A SCORPION-TOXIN MIMIC OF CD4, IN COMPLEX WITH HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN AND ANTI-HIV-1 ANTIBODY 17B | HIV-1, GP120, YU2, SCORPION TOXIN, CD4 MIMIC, CD4M33, ANTIBODY, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
1yym:G (GLY263) to (LEU288) CRYSTAL STRUCTURE OF F23, A SCORPION-TOXIN MIMIC OF CD4, IN COMPLEX WITH HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN AND ANTI-HIV-1 ANTIBODY 17B | HIV-1, GP120, YU2, SCORPION TOXIN, CD4 MIMIC, F23, ANTIBODY, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
3le9:A (GLY349) to (ASN381) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF TACE WITH INDAZOLINONE- PHENYL-HYDANTOIN INHIBITOR | GLYCOPROTEIN, MEMBRANE, METAL-BINDING, METALLOPROTEASE, NOTCH SIGNALING PATHWAY, PHOSPHOPROTEIN, PROTEASE, TRANSMEMBRANE, ZYMOGEN, HYDROLASE
5dp4:C (GLY148) to (ALA172) CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 3 | HAND, FOOT AND MOUTH DISEASE, 3C PROTEINASE, PEPTIDOMIMETICS, DRUG DESIGN, RUPINTRIVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1z8t:A (ASP62) to (LEU115) STRUCTURE OF MUTANT PYRROLIDONE CARBOXYL PEPTIDASE (E192Q) FROM A HYPERTHERMOPHILE, PYROCOCCUS FURIOSUS | PROTEIN STABILITY, HYDROLASE
1z8t:B (ASP62) to (LEU115) STRUCTURE OF MUTANT PYRROLIDONE CARBOXYL PEPTIDASE (E192Q) FROM A HYPERTHERMOPHILE, PYROCOCCUS FURIOSUS | PROTEIN STABILITY, HYDROLASE
1z8t:C (ASP62) to (LEU115) STRUCTURE OF MUTANT PYRROLIDONE CARBOXYL PEPTIDASE (E192Q) FROM A HYPERTHERMOPHILE, PYROCOCCUS FURIOSUS | PROTEIN STABILITY, HYDROLASE
1z8t:D (ASP62) to (LEU115) STRUCTURE OF MUTANT PYRROLIDONE CARBOXYL PEPTIDASE (E192Q) FROM A HYPERTHERMOPHILE, PYROCOCCUS FURIOSUS | PROTEIN STABILITY, HYDROLASE
3lgp:A (GLY349) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TACE WITH BENZIMIDAZOLYL- THIENYL-TARTRATE BASED INHIBITOR | GLYCOPROTEIN, MEMBRANE, METAL-BINDING, METALLOPROTEASE, NOTCH SIGNALING PATHWAY, PHOSPHOPROTEIN, PROTEASE, TRANSMEMBRANE, ZYMOGEN, CLEAVAGE ON PAIR OF BASIC RESIDUES, DISULFIDE BOND, HYDROLASE, SH3- BINDING
5dud:D (GLU124) to (GLY171) CRYSTAL STRUCTURE OF E. COLI YBGJK | PROTEIN COMPLEX, UNKNOWN FUNCTION
1zhm:A (VAL202) to (THR229) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE COAGULATION FACTOR XIA IN COMPLEX WITH BENZAMIDINE (S434A- T475A-K437 MUTANT) | FACTOR XI; BENZAMIDINE, HYDROLASE, BLOOD CLOTTING
3lkw:A (SER187) to (LYS219) CRYSTAL STRUCTURE OF DENGUE VIRUS 1 NS2B/NS3 PROTEASE ACTIVE SITE MUTANT | VIRAL PROTEASE, SERINE PROTEASE, NS3 PROTEASE, NS2B COFACTOR, VIRAL PROTEIN, HYDROLASE
3llx:A (GLN299) to (GLU324) CRYSTAL STRUCTURE OF AN ALA RACEMASE-LIKE PROTEIN (IL1761) FROM IDIOMARINA LOIHIENSIS AT 1.50 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, ISOMERASE
4pzx:A (THR120) to (GLU140) SYNTHESIS, CHARACTERIZATION AND PK/PD STUDIES OF A SERIES OF SPIROCYCLIC PYRANOCHROMENE BACE1 INHIBITORS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1zjd:A (GLY197) to (THR229) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH KUNITZ PROTEASE INHIBITOR DOMAIN OF PROTEASE NEXIN II | COAGULATION FACTOR XI; KUNITZ PROTEASE INHIBITORY DOMAIN; NEXIN II, HYDROLASE, BLOOD CLOTTING
3lnx:D (ILE6) to (ALA60) SECOND PDZ DOMAIN FROM HUMAN PTP1E | PDZ2, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI-2, CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS, CESG, CYTOSKELETON, SIGNALING PROTEIN
1zm2:A (LEU554) to (PRO592) STRUCTURE OF ADP-RIBOSYLATED EEF2 IN COMPLEX WITH CATALYTIC FRAGMENT OF ETA | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
1zm2:E (PRO559) to (PRO592) STRUCTURE OF ADP-RIBOSYLATED EEF2 IN COMPLEX WITH CATALYTIC FRAGMENT OF ETA | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
3lon:A (GLY140) to (ILE170) HCV NS3-4A PROTEASE DOMAIN WITH KETOAMIDE INHIBITOR NARLAPREVIR | HEPATITIS C VIRUS, NS3 PROTEASE DOMAIN, SERINE PROTEASE, MACROCYCLIC KETOAMIDE INHIBITOR, HYDROLASE, ATP-BINDING, CAPSID PROTEIN, ENVELOPE PROTEIN, HELICASE, HOST MEMBRANE, MEMBRANE, NUCLEOTIDE- BINDING, RNA REPLICATION, TRANSMEMBRANE, VIRION, VIRAL PROTEIN, VIRAL PROTEIN-INHIBITOR COMPLEX
3lon:C (GLY140) to (ILE170) HCV NS3-4A PROTEASE DOMAIN WITH KETOAMIDE INHIBITOR NARLAPREVIR | HEPATITIS C VIRUS, NS3 PROTEASE DOMAIN, SERINE PROTEASE, MACROCYCLIC KETOAMIDE INHIBITOR, HYDROLASE, ATP-BINDING, CAPSID PROTEIN, ENVELOPE PROTEIN, HELICASE, HOST MEMBRANE, MEMBRANE, NUCLEOTIDE- BINDING, RNA REPLICATION, TRANSMEMBRANE, VIRION, VIRAL PROTEIN, VIRAL PROTEIN-INHIBITOR COMPLEX
1zm3:E (PRO559) to (PRO592) STRUCTURE OF THE APO EEF2-ETA COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
3lox:A (GLY140) to (ILE170) HCV NS3-4A PROTEASE DOMAIN WITH A KETOAMIDE INHIBITOR DERIVATIVE OF BOCEPREVIR BOUND | NS3 PROTEASE DOMAIN, SERINE PROTEASE, KETOAMIDE INHIBITOR, ATP- BINDING, HYDROLASE, MEMBRANE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3lox:C (GLY140) to (ILE170) HCV NS3-4A PROTEASE DOMAIN WITH A KETOAMIDE INHIBITOR DERIVATIVE OF BOCEPREVIR BOUND | NS3 PROTEASE DOMAIN, SERINE PROTEASE, KETOAMIDE INHIBITOR, ATP- BINDING, HYDROLASE, MEMBRANE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1zm9:C (ALA562) to (PRO592) STRUCTURE OF EEF2-ETA IN COMPLEX WITH PJ34 | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
1zm9:E (PRO559) to (PRO592) STRUCTURE OF EEF2-ETA IN COMPLEX WITH PJ34 | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
3lt3:A (GLY344) to (LEU372) CRYSTAL STRUCTURE OF RV3671C FROM M. TUBERCULOSIS H37RV, SER343ALA MUTANT, INACTIVE FORM | SERINE PROTEASE, H37RV, HTRA, HYDROLASE, PROTEASE
4avr:A (MET29) to (ASN58) CRYSTAL STRUCTURE OF THE HYPOTHETICAL PROTEIN PA4485 FROM PSEUDOMONAS AERUGINOSA | UNKNOWN FUNCTION, GRAM-NEGATIVE BACTERIA, INFECTIOUS DISEASE, STRUCTURE-BASED INHIBITOR DESIGN
4avr:B (MET29) to (VAL54) CRYSTAL STRUCTURE OF THE HYPOTHETICAL PROTEIN PA4485 FROM PSEUDOMONAS AERUGINOSA | UNKNOWN FUNCTION, GRAM-NEGATIVE BACTERIA, INFECTIOUS DISEASE, STRUCTURE-BASED INHIBITOR DESIGN
1zxc:A (LEU348) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TNF-ALPHA CONVERTING ENZYME (TACE) WITH INHIBITOR | TACE/ADAM-17, TACE-INHIBITOR COMPLEX, ZN-ENDOPEPTIDASE, HYDROLASE
5e6i:L (ASN204) to (THR230) CRYSTAL STRUCTURE OF TCR PF8 IN COMPLEX WITH FLU MP(58-66) EPITOPE PRESENTED BY HLA-A2 | IMMUNE SYSTEM, TCR, HLA-A2, FLU, COMPLEX
3lw6:A (ASP147) to (ARG190) CRYSTAL STRUCTURE OF DROSOPHILA BETA1,4-GALACTOSYLTRANSFERASE-7 | PROTEIN-MN-UDP COMPLEX, GLYCOSYLTRANSFERASE, TRANSFERASE
2a4r:A (GLY140) to (ILE170) HCV NS3 PROTEASE DOMAIN WITH A KETOAMIDE INHIBITOR COVALENTLY BOUND. | VIRAL PROTEIN
4b54:A (MET108) to (ASP132) THE STRUCTURE OF THE INACTIVE MUTANT G153R OF LPTC FROM E.COLI | TRANSPORT PROTEIN, INACTIVE MUTANT
4qfg:A (MET134) to (ASP157) STRUCTURE OF AMPK IN COMPLEX WITH STAUROSPORINE INHIBITOR AND IN THE ABSENCE OF A SYNTHETIC ACTIVATOR | CBM, KINASE, AMPK, SIGNALING PROTEIN-INHIBITOR COMPLEX
3m4o:B (GLY902) to (LEU941) RNA POLYMERASE II ELONGATION COMPLEX B | TRANSCRIPTION, MRNA, MULTIPROTEIN COMPLEX, MOLECULAR MACHINE, DNA, DNA DAMAGE, CANCER, PLATINUM DRUG, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, METAL-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
3m4o:B (THR944) to (PRO974) RNA POLYMERASE II ELONGATION COMPLEX B | TRANSCRIPTION, MRNA, MULTIPROTEIN COMPLEX, MOLECULAR MACHINE, DNA, DNA DAMAGE, CANCER, PLATINUM DRUG, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, METAL-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
4b6m:A (ARG159) to (GLU189) TRYPANSOMA BRUCEI TUBULIN BINDING COFACTOR B CAP-GLY DOMAIN | STRUCTURAL PROTEIN
3m5l:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH ITMN-191 | HCV, HEPATITIS C VIRUS, NS3, PROTEASE, DRUG RESISTANCE, SERINE PROTEASE, CHIMERA PROTEIN, FUSION PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3m5m:A (GLY1140) to (ILE1170) AVOIDING DRUG RESISTANCE AGAINST HCV NS3/4A PROTEASE INHIBITORS | HCV, HEPATITIS C VIRUS, NS3, PROTEASE, DRUG RESISTANCE, SERINE PROTEASE, CHIMERA PROTEIN, FUSION PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3m5m:B (GLY1140) to (ILE1170) AVOIDING DRUG RESISTANCE AGAINST HCV NS3/4A PROTEASE INHIBITORS | HCV, HEPATITIS C VIRUS, NS3, PROTEASE, DRUG RESISTANCE, SERINE PROTEASE, CHIMERA PROTEIN, FUSION PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3m5n:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH N-TERMINAL PRODUCT 4B5A | HCV, HEPATITIS C VIRUS, NS3, PROTEASE, DRUG RESISTANCE, SERINE PROTEASE, CHIMERA PROTEIN, FUSION PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3m5n:B (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH N-TERMINAL PRODUCT 4B5A | HCV, HEPATITIS C VIRUS, NS3, PROTEASE, DRUG RESISTANCE, SERINE PROTEASE, CHIMERA PROTEIN, FUSION PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3m5n:C (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH N-TERMINAL PRODUCT 4B5A | HCV, HEPATITIS C VIRUS, NS3, PROTEASE, DRUG RESISTANCE, SERINE PROTEASE, CHIMERA PROTEIN, FUSION PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3m5n:D (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH N-TERMINAL PRODUCT 4B5A | HCV, HEPATITIS C VIRUS, NS3, PROTEASE, DRUG RESISTANCE, SERINE PROTEASE, CHIMERA PROTEIN, FUSION PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4b74:B (GLY140) to (VAL170) DISCOVERY OF AN ALLOSTERIC MECHANISM FOR THE REGULATION OF HCV NS3 PROTEIN FUNCTION | HYDROLASE, HCV, HELICASE-PROTEASE, ALLOSTERIC POCKET, FUSION PROTEIN
4b75:B (GLY140) to (VAL170) DISCOVERY OF AN ALLOSTERIC MECHANISM FOR THE REGULATION OF HCV NS3 PROTEIN FUNCTION | HYDROLASE, HELICASE-PROTEASE, ALLOSTERIC POCKET, FUSION PROTEIN
4b76:A (GLY140) to (VAL170) DISCOVERY OF AN ALLOSTERIC MECHANISM FOR THE REGULATION OF HCV NS3 PROTEIN FUNCTION | HYDROLASE, HELICASE-PROTEASE, ALLOSTERIC POCKET, FUSION PROTEIN
4b76:B (GLY140) to (VAL170) DISCOVERY OF AN ALLOSTERIC MECHANISM FOR THE REGULATION OF HCV NS3 PROTEIN FUNCTION | HYDROLASE, HELICASE-PROTEASE, ALLOSTERIC POCKET, FUSION PROTEIN
2a8h:A (LEU348) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TACE WITH THIOMORPHOLINE SULFONAMIDE HYDROXAMATE INHIBITOR | TACE/ADAM-17, TACE-INHIBITOR COMPLEX, ZN-ENDOPEPTIDASE, HYDROLASE
3m9b:A (ASP181) to (VAL236) CRYSTAL STRUCTURE OF THE AMINO TERMINAL COILED COIL DOMAIN AND THE INTER DOMAIN OF THE MYCOBACTERIUM TUBERCULOSIS PROTEASOMAL ATPASE MPA | COIL COIL WITH 5 BETA-STRAND BARREL INTER DOMAIN, CHAPERONE
3b78:A (ARG564) to (PRO592) STRUCTURE OF THE EEF2-EXOA(R551H)-NAD+ COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, TOXIN-SUBSTRATE COMPLEX, CYTOPLASM, GTP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PROTEIN BIOSYNTHESIS, RNA-BINDING, RRNA- BINDING, GLYCOSYLTRANSFERASE, NAD, TRANSFERASE, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
3b78:E (PRO559) to (PRO592) STRUCTURE OF THE EEF2-EXOA(R551H)-NAD+ COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, TOXIN-SUBSTRATE COMPLEX, CYTOPLASM, GTP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PROTEIN BIOSYNTHESIS, RNA-BINDING, RRNA- BINDING, GLYCOSYLTRANSFERASE, NAD, TRANSFERASE, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
3b82:E (ARG564) to (PRO592) STRUCTURE OF THE EEF2-EXOA(E546H)-NAD+ COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, TOXIN-SUBSTRATE COMPLEX, CYTOPLASM, GTP-BINDING, NUCLEOTIDE-BINDING, PHOSPHORYLATION, PROTEIN BIOSYNTHESIS, RNA-BINDING, RRNA- BINDING, GLYCOSYLTRANSFERASE, NAD, TRANSFERASE, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
4bbs:B (VAL903) to (LEU941) STRUCTURE OF AN INITIALLY TRANSCRIBING RNA POLYMERASE II- TFIIB COMPLEX | TRANSCRIPTION
3b8h:C (PRO559) to (PRO592) STRUCTURE OF THE EEF2-EXOA(E546A)-NAD+ COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, TOXIN-SUBSTRATE COMPLEX, CYTOPLASM, GTP-BINDING, NUCLEOTIDE-BINDING, PHOSPHORYLATION, PROTEIN BIOSYNTHESIS, RNA-BINDING, RRNA- BINDING, GLYCOSYLTRANSFERASE, NAD, TRANSFERASE, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
3b8h:E (PRO559) to (PRO592) STRUCTURE OF THE EEF2-EXOA(E546A)-NAD+ COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, TOXIN-SUBSTRATE COMPLEX, CYTOPLASM, GTP-BINDING, NUCLEOTIDE-BINDING, PHOSPHORYLATION, PROTEIN BIOSYNTHESIS, RNA-BINDING, RRNA- BINDING, GLYCOSYLTRANSFERASE, NAD, TRANSFERASE, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
5eqq:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF HCV NS3/4A WT PROTEASE IN COMPLEX WITH 5172- LINEAR (MK-5172 LINEAR ANALOGUE) | MACROCYCLIZATION, MK-5172 ANALOGUE, GRAZOPREVIR, HCV PROTEASE INHIBITOR RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5eqr:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF A GENOTYPE 1A/3A CHIMERIC HCV NS3/4A PROTEASE IN COMPLEX WITH DANOPREVIR | DANOPREVIR, DRUG RESISTANCE, HCV PROTEASE INHIBITOR, GENOTYPE 3, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5eqs:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF A GENOTYPE 1A/3A CHIMERIC HCV NS3/4A PROTEASE IN COMPLEX WITH ASUNAPREVIR | ASUNAPREVIR, DRUG RESISTANCE, HCV PROTEASE INHIBITOR, GENOTYPE 3, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3mo7:A (LEU224) to (SER245) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 2'-FLUORO-6-IODO-UMP | UMP SYNTHASE, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, 2'-FLUORO-6- IODO-UMP, LYASE
5esb:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF A GENOTYPE 1A/3A CHIMERIC HCV NS3/4A PROTEASE IN COMPLEX WITH VANIPREVIR | VANIPREVIR, DRUG RESISTANCE, HCV PROTEASE INHIBITOR, GENOTYPE 3, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3bgj:A (LEU224) to (SER245) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 6-IODO-UMP | UMP SYNTHASE, C-TERMINAL DOMAIN, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, HUMAN, 6-IODO-UMP, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
4qti:U (CYS147) to (CYS171) CRYSTAL STRUCTURE OF HUMAN UPAR IN COMPLEX WITH ANTI-UPAR FAB 8B12 | ALLOSTERIC REGULATION, CELL SURFACE, IMMUNE SYSTEM
3mqk:C (ASP28) to (LYS56) CBF5-NOP10-GAR1 COMPLEX BINDING WITH 17MER RNA CONTAINING ACA TRINUCLEOTIDE | PROTEIN-RNA COMPLEX, BOX H/ACA, PSEUDOURIDINE SYNTHASE, POST- TRANSCRIPTIONAL MODIFICATION, ISOMERASE, TRNA PROCESSING, RNA- BINDING, ISOMERASE-RNA BINDING PROTEIN-RNA COMPLEX
3msl:A (THR59) to (GLU79) FRAGMENT BASED DISCOVERY AND OPTIMISATION OF BACE-1 INHIBITORS | PROTEASE, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, AMYLOID PRECURSOR PROTEIN SECRETASES, ASPARTIC ENDOPEPTIDASES, FRAGMENT- BASED DRUG DESIGN, FLUORESCENCE POLARISATION, TRANSMEMBRANE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3mt1:A (SER239) to (ASP260) CRYSTAL STRUCTURE OF PUTATIVE CARBOXYNORSPERMIDINE DECARBOXYLASE PROTEIN FROM SINORHIZOBIUM MELILOTI | PSI2, MCSG, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, CARBOXYNORSPERMIDINE DECARBOXYLASE, LYASE
3bk0:A (LEU224) to (SER245) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 5-CN-UMP | UMP SYNTHASE, C-TERMINAL DOMAIN, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, HUMAN, 5-CN-UMP, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
3bkj:H (THR107) to (PRO147) CRYSTAL STRUCTURE OF FAB WO2 BOUND TO THE N TERMINAL DOMAIN OF AMYLOID BETA PEPTIDE (1-16) | ABETA, AMYLOID BETA PEPTIDE, FAB, WO2, ALZHEIMER'S DISEASE, IMMUNOTHERAPIES, APP, IMMUNE SYSTEM
5exr:C (GLU338) to (PHE362) CRYSTAL STRUCTURE OF HUMAN PRIMOSOME | HUMAN PRIMOSOME, COMPLEX, PRIMASE, DNA POLYMERASE ALPHA, PRIMER, DNA REPLICATION, DNA, RNA, REPLICASE, REPLICATION
4bls:A (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 Q278A MUTANT IN COMPLEX WITH AMPCPP | HYDROLASE, PACKAGING, CYSTOVIRIDAE
4bls:B (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 Q278A MUTANT IN COMPLEX WITH AMPCPP | HYDROLASE, PACKAGING, CYSTOVIRIDAE
4bls:C (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 Q278A MUTANT IN COMPLEX WITH AMPCPP | HYDROLASE, PACKAGING, CYSTOVIRIDAE
4blt:C (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 S292A MUTANT IN COMPLEX WITH AMPCPP | HYDROLASE, CYSTOVIRIDAE
3mw7:A (LEU224) to (SER245) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 5-FLUORO-UMP(PRODUCED FROM 5-FLUORO-6-AMINO-UMP) | UMP SYNTHASE, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, HUMAN, 5- FLUORO-6-AMINO-UMP, LYASE
3mwi:U (GLY197) to (THR229) THE COMPLEX CRYSTAL STRUCTURE OF UROKIANSE AND 5-NITRO-1H-INDOLE-2- AMIDINE | HYDROLASE
3bvj:A (LEU224) to (SER245) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH XMP | HUMAN, UMP SYNTHASE, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, XMP, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
3bvj:B (LEU224) to (SER245) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH XMP | HUMAN, UMP SYNTHASE, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, XMP, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
3byy:B (TYR32) to (GLU67) MANIPULATING THE COUPLED FOLDING AND BINDING PROCESS DRIVES AFFINITY MATURATION IN A PROTEIN-PROTEIN COMPLEX | SECRETED, SUPERANTIGEN, TOXIN
5fa2:A (GLY263) to (LEU288) CRYSTAL STRUCTURE OF 426C.TM4DELTAV1-3 P120 | ANTIBODY, IMMUNE SYSTEM, HIV-1
5fa2:B (GLY263) to (LEU288) CRYSTAL STRUCTURE OF 426C.TM4DELTAV1-3 P120 | ANTIBODY, IMMUNE SYSTEM, HIV-1
4r1z:B (ILE382) to (LYS399) ZEBRA FISH CYTOCHROME P450 17A1 WITH ABIRATERONE | CYTOCHROME P450 17A1, ABIRATERONE, 17 (ALPHA)-HYDROXYLATION, 17ALPHA, 20-LYASE, STEROID BIOSYNTHESIS, ENZYME KINETICS, OXIDOREDUCTASE
4r5n:A (THR120) to (GLU140) 8-TETRAHYDROPYRAN-2-YL CHROMANS: HIGHLY SELECTIVE BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1 (BACE1) INHIBITORS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3c4p:B (GLY141) to (ASP163) CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA- LACTAMASE INHIBITOR PROTEIN (BLIP) E73M COMPLEX | BETA-LACTAMASE, BETA-LACTAMASE INHIBITORY PROTEIN, PROTEIN- PROTEIN COMPLEX, BLIP, SHV-1, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, SECRETED, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3n7o:A (GLY197) to (THR229) X-RAY STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH SMALL MOLECULE INHIBITOR. | SERINE PROTEASE, HYDROLASE
5fhg:A (ARG282) to (ARG313) STRUCTURE OF UNLIGANDED PIF1 FROM BACTEROIDES SP | PIF1 HELICASE, DNA HELICASE, HYDROLASE
5fht:A (GLY174) to (ILE200) HTRA2 PROTEASE MUTANT V226K | HYDROLASE, APOPTOSIS
3c7u:B (GLY141) to (ASP163) STRUCTURAL INSIGHT INTO THE KINETICS AND CP OF INTERACTIONS BETWEEN TEM-1-LACTAMASE AND BLIP | ENZYME-INHIBITOR COMPLEX, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, SECRETED, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3c7v:B (GLY141) to (ASP163) STRUCTURAL INSIGHT INTO THE KINETICS AND DELTA-CP OF INTERACTIONS BETWEEN TEM-1 BETA-LACTAMASE AND BLIP | ENZYME-INHIBITOR COMPLEX, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, SECRETED, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3n93:A (LEU59) to (THR76) CRYSTAL STRUCTURE OF HUMAN CRFR2 ALPHA EXTRACELLULAR DOMAIN IN COMPLEX WITH UROCORTIN 3 | CLASS B-GPCR, EXTRACELLULAR DOMAIN, CRFR2 ALPHA EXTRACELLULAR DOMAIN, NEUROPEPTIDE, SELECTIVITY, MEMBRANE PROTEIN, HORMONE
4r7h:A (ASN773) to (ILE794) CRYSTAL STRUCTURE OF FMS KINASE DOMAIN WITH A SMALL MOLECULAR INHIBITOR, PLX3397 | CSF-1-R, FMS PROTO-ONCOGENE, C-FMS, CD115 ANTIGEN, KINASE, ATP- BINDING, PLX3397, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3n95:C (LEU59) to (THR76) CRYSTAL STRUCTURE OF HUMAN CRFR2 ALPHA EXTRACELLULAR DOMAIN IN COMPLEX WITH UROCORTIN 2 | CLASS B-GPCR, EXTRACELLULAR DOMAIN, CRFR2 ALPHA EXTRACELLULAR DOMAIN, NEUROPEPTIDE,SELECTIVITY, MEMBRANE PROTEIN, HORMONE
3n96:A (LEU59) to (THR76) CRYSTAL STRUCTURE OF HUMAN CRFR2 ALPHA EXTRACELLULAR DOMAIN IN COMPLEX WITH UROCORTIN 1 | CLASS B-GPCR, EXTRACELLULAR DOMAIN, CRFR2 ALPHA EXTRACELLULAR DOMAIN, NEUROPEPTIDE,SELECTIVITY, MEMBRANE PROTEIN, HORMONE
3n96:B (LEU59) to (THR76) CRYSTAL STRUCTURE OF HUMAN CRFR2 ALPHA EXTRACELLULAR DOMAIN IN COMPLEX WITH UROCORTIN 1 | CLASS B-GPCR, EXTRACELLULAR DOMAIN, CRFR2 ALPHA EXTRACELLULAR DOMAIN, NEUROPEPTIDE,SELECTIVITY, MEMBRANE PROTEIN, HORMONE
3n96:C (LEU59) to (THR76) CRYSTAL STRUCTURE OF HUMAN CRFR2 ALPHA EXTRACELLULAR DOMAIN IN COMPLEX WITH UROCORTIN 1 | CLASS B-GPCR, EXTRACELLULAR DOMAIN, CRFR2 ALPHA EXTRACELLULAR DOMAIN, NEUROPEPTIDE,SELECTIVITY, MEMBRANE PROTEIN, HORMONE
3cdd:C (THR301) to (ARG338) CRYSTAL STRUCTURE OF PROPHAGE MUSO2, 43 KDA TAIL PROTEIN FROM SHEWANELLA ONEIDENSIS | MUSO2, SHEWANELLA ONEIDENSIS MR-1, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, STRUCTURAL PROTEIN
4rdp:B (ASP134) to (LEU156) CRYSTAL STRUCTURE OF CMR4 | RRM, RNA BINDING PROTEIN, FERREDOXIN-LIKE FOLD
4c2m:B (TYR851) to (SER877) STRUCTURE OF RNA POLYMERASE I AT 2.8 A RESOLUTION | TRANSCRIPTION, RIBOSOME BIOGENESIS
4rft:e (THR165) to (VAL209) T=1 SUBVIRAL PARTICLE OF GROUPER NERVOUS NECROSIS VIRUS CAPSID PROTEIN DELETION MUTANT (DELTA 1-34 & 218-338) | VIRUS, SHELL DOMAIN
3ngb:A (GLY263) to (LEU288) CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC01 IN COMPLEX WITH HIV-1 GP120 | HIV, GP120, ANTIBODY, VRC01, NEUTRALIZATION, VACCINE, ENVELOPE GLYCOPROTEIN, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
3ngb:D (GLY263) to (LEU288) CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC01 IN COMPLEX WITH HIV-1 GP120 | HIV, GP120, ANTIBODY, VRC01, NEUTRALIZATION, VACCINE, ENVELOPE GLYCOPROTEIN, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
5flm:B (VAL858) to (LEU896) STRUCTURE OF TRANSCRIBING MAMMALIAN RNA POLYMERASE II | TRANSCRIPTION, ELONGATION
5fn0:A (GLU77) to (PRO97) CRYSTAL STRUCTURE OF PSEUDOMONAS FLUORESCENS KYNURENINE-3- MONOOXYGENASE (KMO) IN COMPLEX WITH GSK180 | OXIDOREDUCTASE, KMO
5fn0:B (GLU77) to (PRO97) CRYSTAL STRUCTURE OF PSEUDOMONAS FLUORESCENS KYNURENINE-3- MONOOXYGENASE (KMO) IN COMPLEX WITH GSK180 | OXIDOREDUCTASE, KMO
5fn0:C (GLU77) to (PRO97) CRYSTAL STRUCTURE OF PSEUDOMONAS FLUORESCENS KYNURENINE-3- MONOOXYGENASE (KMO) IN COMPLEX WITH GSK180 | OXIDOREDUCTASE, KMO
5fn0:D (GLU77) to (PRO97) CRYSTAL STRUCTURE OF PSEUDOMONAS FLUORESCENS KYNURENINE-3- MONOOXYGENASE (KMO) IN COMPLEX WITH GSK180 | OXIDOREDUCTASE, KMO
4c7l:A (GLY214) to (SER247) CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS STRAIN S HEMAGGLUTININ-ESTERASE | HYDROLASE, RECEPTOR DESTROYING, RECEPTOR BINDING, 4-O-ACETYLATED SIALIC ACID
4c7w:A (GLY214) to (SER247) CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS STRAIN S HEMAGGLUTININ-ESTERASE IN COMPLEX WITH 4-O-ACETYLATED SIALIC ACID | HYDROLASE, RECEPTOR DESTROYING, RECEPTOR BINDING
4ri0:B (GLY306) to (ILE332) SERINE PROTEASE HTRA3, MUTATIONALLY INACTIVATED | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, NATIONAL SCIENCE CENTER - POLAND, PROTEASE, HYDROLASE
5fps:A (GLY140) to (VAL170) STRUCTURE OF HEPATITIS C VIRUS (HCV) FULL-LENGTH NS3 COMPLEX WITH SMALL-MOLECULE LIGAND 3-AMINOBENZENE-1,2- DICARBOXYLIC ACID (AT1246) IN AN ALTERNATE BINDING SITE. | HEPATITIS C VIRUS, HCV, NS3 COMPLEX, PROTEASE-HELICASE, HYDROLASE, PROTEIN-LIGAND COMPLEX, FRAGMENT SCREENING, ALTERNATE BINDING SITE, AT1246.
5fpt:A (GLY140) to (VAL170) STRUCTURE OF HEPATITIS C VIRUS (HCV) FULL-LENGTH NS3 COMPLEX WITH SMALL-MOLECULE LIGAND 2-(1-METHYL-1H-INDOL-3- YL)ACETIC ACID (AT3437) IN AN ALTERNATE BINDING SITE. | HEPATITIS C VIRUS, HCV, NS3 COMPLEX, PROTEASE-HELICASE, HYDROLASE, PROTEIN-LIGAND COMPLEX, FRAGMENT SCREENING, ALTERNATE BINDING SITE, AT3437.
5fpt:B (GLY140) to (VAL170) STRUCTURE OF HEPATITIS C VIRUS (HCV) FULL-LENGTH NS3 COMPLEX WITH SMALL-MOLECULE LIGAND 2-(1-METHYL-1H-INDOL-3- YL)ACETIC ACID (AT3437) IN AN ALTERNATE BINDING SITE. | HEPATITIS C VIRUS, HCV, NS3 COMPLEX, PROTEASE-HELICASE, HYDROLASE, PROTEIN-LIGAND COMPLEX, FRAGMENT SCREENING, ALTERNATE BINDING SITE, AT3437.
5fpy:A (GLY140) to (VAL170) STRUCTURE OF HEPATITIS C VIRUS (HCV) FULL-LENGTH NS3 COMPLEX WITH SMALL-MOLECULE LIGAND 5-BROMO-1-METHYL-1H-INDOLE-2- CARBOXYLIC ACID (AT21457) IN AN ALTERNATE BINDING SITE. | HEPATITIS C VIRUS, HCV, NS3 COMPLEX, PROTEASE-HELICASE, HYDROLASE, PROTEIN-LIGAND COMPLEX, FRAGMENT SCREENING, ALTERNATE BINDING SITE, AT21457.
4rko:B (ARG206) to (THR229) CRYSTAL STRUCTURE OF THROMBIN MUTANT S195T BOUND WITH PPACK | TRYPSIN-LIKE PROTEASES, CATALYSIS, ALLOSTERIC REGULATION, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4cc4:F (ASN1515) to (SER1535) COMPLEX OF INLC OF LISTERIA MONOCYTOGENES AND HUMAN TUBA C- TERMINAL SH3 DOMAIN | CELL INVASION, BACTERIAL INFECTION, PATHOGENESIS, LISTERIAL CELL-CELL SPREAD, VIRULENCE FACTOR, PROTEIN-PROTEIN INTERACTIONS, LEUCINE-RICH REPEAT, SRC HOMOLOGY 3 DOMAIN, DISRUPTION OF CORTICAL TENSION, CELL MEMBRANE PROTRUSIONS
5ftb:A (ARG282) to (ARG313) CRYSTAL STRUCTURE OF PIF1 HELICASE FROM BACTEROIDES IN COMPLEX WITH AMPPNP | HYDROLASE, SF1B, G QUADRUPLEX, SH3 DOMAIN, CONFORMATIONAL CHANGE
5fte:A (ARG282) to (ARG313) CRYSTAL STRUCTURE OF PIF1 HELICASE FROM BACTEROIDES IN COMPLEX WITH ADP-ALF3 AND SSDNA | HYDROLASE, SF1B, G QUADRUPLEX, SH3 DOMAIN, CONFORMATIONAL CHANGE
3nsm:A (GLY291) to (ASN335) CRYSTAL STRUCTURE OF INSECT BETA-N-ACETYL-D-HEXOSAMINIDASE OFHEX1 FROM OSTRINIA FURNACALIS | BETA-N-ACETYL-D-HEXOSAMINIDASE, HYDROLASE
3nsn:A (GLY291) to (LEU334) CRYSTAL STRUCTURE OF INSECT BETA-N-ACETYL-D-HEXOSAMINIDASE OFHEX1 COMPLEXED WITH TMG-CHITOTRIOMYCIN | BETA-N-ACETYL-D-HEXOSAMINIDASE, HYDROLASE
3nsw:E (SER54) to (LEU88) CRYSTAL STRUCTURE OF ANCYLOSTOMA CEYLANICUM EXCRETORY-SECRETORY PROTEIN 2 | ANCYLOSTOMA CEYLANICUM, HOOKWORM, EXCRETORY-SECRETORY PROTEIN, MEROHEDRAL TWINNING, IMMUNOMODULATOR, NETRIN DOMAIN, IMMUNE SYSTEM
4rnl:B (ASN84) to (THR101) THE CRYSTAL STRUCTURE OF A POSSIBLE GALACTOSE MUTAROTASE FROM STREPTOMYCES PLATENSIS SUBSP. ROSACEUS | STRUCTURAL GENOMICS, PSI-BIOLOGY, MCSG, ENZYME DISCOVERY FOR NATURAL PRODUCT BIOSYNTHESIS, NATPRO, MIDWEST CENTER FOR STRUCTURAL GENOMICS, UNKNOWN FUNCTION
3cp7:A (GLY171) to (PRO201) CRYSTAL STRUCTURE OF A THERMOSTABLE SERINE PROTEASE AL20 FROM EXTREMOPHILIC MICROOGANISM | TRYPSIN-LIKE, HYDROLASE
3cp7:B (GLY171) to (PRO201) CRYSTAL STRUCTURE OF A THERMOSTABLE SERINE PROTEASE AL20 FROM EXTREMOPHILIC MICROOGANISM | TRYPSIN-LIKE, HYDROLASE
3num:A (GLY329) to (ILE355) SUBSTRATE INDUCED REMODELING OF THE ACTIVE SITE REGULATES HTRA1 ACTIVITY | SERINE PROTEASE, DEGP, HTRA, PROTEASE, HYDROLASE
4rqs:G (GLY263) to (ASN289) CRYSTAL STRUCTURE OF FULLY GLYCOSYLATED HIV-1 GP120 CORE BOUND TO CD4 AND 17B FAB | IMMUNOGLOBULIN FOLD, N-LINKED GLYCOSYLATION, IMMUNE SYSTEM
3nwu:A (GLY329) to (ILE355) SUBSTRATE INDUCED REMODELING OF THE ACTIVE SITE REGULATES HTRA1 ACTIVITY | SERINE PROTEASE, DEGP, HTRA, PROTEASE, HYDROLASE
3nwu:C (GLY329) to (ILE355) SUBSTRATE INDUCED REMODELING OF THE ACTIVE SITE REGULATES HTRA1 ACTIVITY | SERINE PROTEASE, DEGP, HTRA, PROTEASE, HYDROLASE
4ru4:A (GLY594) to (SER624) CRYSTAL STRUCTURE OF THE TAILSPIKE PROTEIN GP49 FROM PSEUDOMONAS PHAGE LKA1 | TAIL SPIKE PROTEIN, BASEPLATE, PHAGE LKA1, LYASE, STRUCTURAL PROTEIN
4ru4:B (THR484) to (ASN509) CRYSTAL STRUCTURE OF THE TAILSPIKE PROTEIN GP49 FROM PSEUDOMONAS PHAGE LKA1 | TAIL SPIKE PROTEIN, BASEPLATE, PHAGE LKA1, LYASE, STRUCTURAL PROTEIN
4ru4:C (THR484) to (ASN509) CRYSTAL STRUCTURE OF THE TAILSPIKE PROTEIN GP49 FROM PSEUDOMONAS PHAGE LKA1 | TAIL SPIKE PROTEIN, BASEPLATE, PHAGE LKA1, LYASE, STRUCTURAL PROTEIN
4ru4:D (GLY594) to (SER624) CRYSTAL STRUCTURE OF THE TAILSPIKE PROTEIN GP49 FROM PSEUDOMONAS PHAGE LKA1 | TAIL SPIKE PROTEIN, BASEPLATE, PHAGE LKA1, LYASE, STRUCTURAL PROTEIN
4ru4:E (GLY594) to (SER624) CRYSTAL STRUCTURE OF THE TAILSPIKE PROTEIN GP49 FROM PSEUDOMONAS PHAGE LKA1 | TAIL SPIKE PROTEIN, BASEPLATE, PHAGE LKA1, LYASE, STRUCTURAL PROTEIN
3nzi:A (GLY329) to (ILE355) SUBSTRATE INDUCED REMODELING OF THE ACTIVE SITE REGULATES HTRA1 ACTIVITY | SERINE PROTEASE, DEGP, HTRA, PROTEASE, HYDROLASE-PEPTIDE INHIBITOR COMPLEX, HYDROLASE-HYDROLASE SUBSTRATE COMPLEX
3cw8:X (THR394) to (PRO414) 4-CHLOROBENZOYL-COA LIGASE/SYNTHETASE, BOUND TO 4CBA-ADENYLATE | ADENYLATE-FORMING ENZYMES, ACYL-COA LIGASE, LIGASE
5fyj:G (GLY263) to (LYS289) CRYSTAL STRUCTURE AT 3.4 A RESOLUTION OF FULLY GLYCOSYLATED HIV-1 CLADE G X1193.C1 SOSIP.664 PREFUSION ENV TRIMER IN COMPLEX WITH BROADLY NEUTRALIZING ANTIBODIES PGT122, 35O22 AND VRC01 | VIRAL PROTEIN, HIV, ENVELOPE, GLYCAN, TRIMER
4rz8:D (GLY263) to (ASN289) CRYSTAL STRUCTURE OF HIV-1 GP120 CORE IN COMPLEX WITH NBD-11021, A SMALL MOLECULE CD4-ANTAGONIST | HIV-1 GP120, NBD-11021, SMALL MOLECULE CD4-ANTAGONIST, PHE 43 CAVITY, VIRAL PROTEIN
3o64:A (GLY349) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TACE WITH 2-(2-AMINOTHIAZOL- 4-YL)PYRROLIDINE-BASED TARTRATE DIAMIDES | HYDROLASE, ADAM PROTEINS, ENZYME INHIBITORS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3o64:B (LEU348) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TACE WITH 2-(2-AMINOTHIAZOL- 4-YL)PYRROLIDINE-BASED TARTRATE DIAMIDES | HYDROLASE, ADAM PROTEINS, ENZYME INHIBITORS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3d12:D (ASN478) to (GLY523) CRYSTAL STRUCTURES OF NIPAH VIRUS G ATTACHMENT GLYCOPROTEIN IN COMPLEX WITH ITS RECEPTOR EPHRIN-B3 | BETA PROPELLER, PROTEIN-RECEPTOR COMPLEX, ENVELOPE PROTEIN, GLYCOPROTEIN, HEMAGGLUTININ, HYDROLASE, MEMBRANE, SIGNAL-ANCHOR, TRANSMEMBRANE, VIRION, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, NEUROGENESIS, HYDROLASE-MEMBRANE PROTEIN COMPLEX
3o8b:A (GLY140) to (VAL170) VISUALIZING ATP-DEPENDENT RNA TRANSLOCATION BY THE NS3 HELICASE FROM HCV | HELICASE, NTPASE, HCV, RNA, TRANSLOCATION, PROTEIN-RNA COMPLEX, PROTEASE/NTPASE/HELICASE, HYDROLASE
4sgb:E (GLY196) to (GLN229) STRUCTURE OF THE COMPLEX OF STREPTOMYCES GRISEUS PROTEINASE B AND POLYPEPTIDE CHYMOTRYPSIN INHIBITOR-1 FROM RUSSET BURBANK POTATO TUBERS AT 2.1 ANGSTROMS RESOLUTION | COMPLEX(SERINE PROTEINASE-INHIBITOR)
3oae:A (LEU42) to (GLY67) CRYSTAL STRUCTURE OF HPV16 L1 PENTAMER BOUND TO HEPARIN OLIGOSACCHARIDES | JELLY ROLL, CAPSID PROTEIN, RECEPTOR HSPG, VIRUS CAPSID, VIRAL PROTEIN
3oae:C (LEU42) to (GLY67) CRYSTAL STRUCTURE OF HPV16 L1 PENTAMER BOUND TO HEPARIN OLIGOSACCHARIDES | JELLY ROLL, CAPSID PROTEIN, RECEPTOR HSPG, VIRUS CAPSID, VIRAL PROTEIN
3oae:D (LEU42) to (GLY67) CRYSTAL STRUCTURE OF HPV16 L1 PENTAMER BOUND TO HEPARIN OLIGOSACCHARIDES | JELLY ROLL, CAPSID PROTEIN, RECEPTOR HSPG, VIRUS CAPSID, VIRAL PROTEIN
3oae:E (LEU42) to (GLY67) CRYSTAL STRUCTURE OF HPV16 L1 PENTAMER BOUND TO HEPARIN OLIGOSACCHARIDES | JELLY ROLL, CAPSID PROTEIN, RECEPTOR HSPG, VIRUS CAPSID, VIRAL PROTEIN
3oe7:D (SER6) to (GLU26) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: GAMMA-I270T | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, ADP, PO4, MITOCHONDRIA, HYDROLASE
3der:C (ASN6) to (SER28) CRYSTAL STRUCTURE OF DIPEPTIDE EPIMERASE FROM THERMOTOGA MARITIMA COMPLEXED WITH L-ALA-L-LYS DIPEPTIDE | DIPEPTIDE EPIMERASE, THERMOTOGA MARITIMA, ENZYMATIC FUNCTION, ISOMERASE
3ofn:K (GLU53) to (VAL76) STRUCTURE OF FOUR MUTANT FORMS OF YEAST F1 ATPASE: ALPHA-N67I | ATP SYNTHASE, ATP PHOSPHATASE, F1F0 ATPASE, ATP SYNTHESIS, HYDROLASE, ADP, PO4, MITOCHONDRIA
3ogj:C (TYR135) to (MET158) CRYSTAL STRUCTURE OF PARTIAL APO (92-227) OF CGMP-DEPENDENT PROTEIN KINASE | SERINE/THREONINE KINASE, TF2I AND IRAG, TRANSFERASE
3ohx:A (GLN258) to (SER281) MOLECULAR BASIS FOR COMPLEMENT RECOGNITION AND INHIBITION DETERMINED BY CRYSTALLOGRAPHIC STUDIES OF THE STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) BOUND TO C3C AND C3B | COMPLEMENT COMPONENT C3, COMPLEMENT ALTERNATE PATHWAY, COMPLEMENT PATHWAY, CONVERTASE, IMMUNE EVASION, INNATE IMMUNITY, SECRETED VIRULENCE FACTOR, IMMUNE SYSTEM
3ohx:D (GLN258) to (SER281) MOLECULAR BASIS FOR COMPLEMENT RECOGNITION AND INHIBITION DETERMINED BY CRYSTALLOGRAPHIC STUDIES OF THE STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) BOUND TO C3C AND C3B | COMPLEMENT COMPONENT C3, COMPLEMENT ALTERNATE PATHWAY, COMPLEMENT PATHWAY, CONVERTASE, IMMUNE EVASION, INNATE IMMUNITY, SECRETED VIRULENCE FACTOR, IMMUNE SYSTEM
3dlp:X (THR394) to (PRO414) 4-CHLOROBENZOYL-COA LIGASE/SYNTHETASE, MUTANT D402P, BOUND TO 4CB | ADENYLATE-FORMING ENZYMES ACYL-COA LIGASE DOMAIN ALTERNATION
4twd:F (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH MEMANTINE | ELIC, LGIC, CYS-LOOP, CHANNEL, MEMANTINE, PORE BLOCKER, TRANSPORT PROTEIN
4twd:I (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH MEMANTINE | ELIC, LGIC, CYS-LOOP, CHANNEL, MEMANTINE, PORE BLOCKER, TRANSPORT PROTEIN
4twf:A (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH BROMOMEMANTINE | ELIC, LGIC, CYS-LOOP, CHANNEL, MEMANTINE, PORE BLOCKER, TRANSPORT PROTEIN
4twf:G (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH BROMOMEMANTINE | ELIC, LGIC, CYS-LOOP, CHANNEL, MEMANTINE, PORE BLOCKER, TRANSPORT PROTEIN
4twh:D (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F16'S | ELIC, LGIC, CYS-LOOP, CHANNEL, TRANSPORT PROTEIN
4twh:E (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F16'S | ELIC, LGIC, CYS-LOOP, CHANNEL, TRANSPORT PROTEIN
4twh:I (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F16'S | ELIC, LGIC, CYS-LOOP, CHANNEL, TRANSPORT PROTEIN
4twh:J (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F16'S | ELIC, LGIC, CYS-LOOP, CHANNEL, TRANSPORT PROTEIN
4d47:C (GLN178) to (GLU220) X-RAY STRUCTURE OF THE LEVANSUCRASE FROM ERWINIA AMYLOVORA | TRANSFERASE, GLYCOSIDE HYDROLASE FAMILY 68, SUCROSE HYDROLYSIS, FIVE- BLADED BETA-PROPELLER, FIRE BLIGHT
4twp:A (ASN358) to (VAL379) THE CRYSTAL STRUCTURE OF HUMAN ABL1 T315I GATEKEEPER MUTANT KINASE DOMAIN IN COMPLEX WITH AXITINIB | GATEKEEPER MUTANT KINASE DOMAIN DFGIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4tyd:A (GLY140) to (VAL170) STRUCTURE-BASED DESIGN OF A NOVEL SERIES OF AZETIDINE INHIBITORS OF THE HEPATITIS C VIRUS NS3/4A SERINE PROTEASE | STRUCTURE-BASED DESIGN, HCV NS3/4A SERINE PROTEASE, AZETIDINE INHIBITORS, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4tyd:B (GLY140) to (VAL170) STRUCTURE-BASED DESIGN OF A NOVEL SERIES OF AZETIDINE INHIBITORS OF THE HEPATITIS C VIRUS NS3/4A SERINE PROTEASE | STRUCTURE-BASED DESIGN, HCV NS3/4A SERINE PROTEASE, AZETIDINE INHIBITORS, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4tyd:C (GLY140) to (VAL170) STRUCTURE-BASED DESIGN OF A NOVEL SERIES OF AZETIDINE INHIBITORS OF THE HEPATITIS C VIRUS NS3/4A SERINE PROTEASE | STRUCTURE-BASED DESIGN, HCV NS3/4A SERINE PROTEASE, AZETIDINE INHIBITORS, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4tyd:D (GLY140) to (VAL170) STRUCTURE-BASED DESIGN OF A NOVEL SERIES OF AZETIDINE INHIBITORS OF THE HEPATITIS C VIRUS NS3/4A SERINE PROTEASE | STRUCTURE-BASED DESIGN, HCV NS3/4A SERINE PROTEASE, AZETIDINE INHIBITORS, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4tyd:H (GLY140) to (VAL170) STRUCTURE-BASED DESIGN OF A NOVEL SERIES OF AZETIDINE INHIBITORS OF THE HEPATITIS C VIRUS NS3/4A SERINE PROTEASE | STRUCTURE-BASED DESIGN, HCV NS3/4A SERINE PROTEASE, AZETIDINE INHIBITORS, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4tyd:J (GLY140) to (VAL170) STRUCTURE-BASED DESIGN OF A NOVEL SERIES OF AZETIDINE INHIBITORS OF THE HEPATITIS C VIRUS NS3/4A SERINE PROTEASE | STRUCTURE-BASED DESIGN, HCV NS3/4A SERINE PROTEASE, AZETIDINE INHIBITORS, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4tyd:L (GLY140) to (VAL170) STRUCTURE-BASED DESIGN OF A NOVEL SERIES OF AZETIDINE INHIBITORS OF THE HEPATITIS C VIRUS NS3/4A SERINE PROTEASE | STRUCTURE-BASED DESIGN, HCV NS3/4A SERINE PROTEASE, AZETIDINE INHIBITORS, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4tyd:M (GLY140) to (VAL170) STRUCTURE-BASED DESIGN OF A NOVEL SERIES OF AZETIDINE INHIBITORS OF THE HEPATITIS C VIRUS NS3/4A SERINE PROTEASE | STRUCTURE-BASED DESIGN, HCV NS3/4A SERINE PROTEASE, AZETIDINE INHIBITORS, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4u01:A (GLY140) to (VAL170) HCV NS3/4A SERINE PROTEASE IN COMPLEX WITH 6570 | HVC, NS3/4A PROTEASE, DRUG DESIGN, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4u01:B (GLY140) to (VAL170) HCV NS3/4A SERINE PROTEASE IN COMPLEX WITH 6570 | HVC, NS3/4A PROTEASE, DRUG DESIGN, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4u01:C (GLY140) to (VAL170) HCV NS3/4A SERINE PROTEASE IN COMPLEX WITH 6570 | HVC, NS3/4A PROTEASE, DRUG DESIGN, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4u01:D (GLY140) to (VAL170) HCV NS3/4A SERINE PROTEASE IN COMPLEX WITH 6570 | HVC, NS3/4A PROTEASE, DRUG DESIGN, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4u01:G (GLY140) to (VAL170) HCV NS3/4A SERINE PROTEASE IN COMPLEX WITH 6570 | HVC, NS3/4A PROTEASE, DRUG DESIGN, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4u01:H (GLY140) to (VAL170) HCV NS3/4A SERINE PROTEASE IN COMPLEX WITH 6570 | HVC, NS3/4A PROTEASE, DRUG DESIGN, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4u01:J (GLY140) to (VAL170) HCV NS3/4A SERINE PROTEASE IN COMPLEX WITH 6570 | HVC, NS3/4A PROTEASE, DRUG DESIGN, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
3opt:A (ILE68) to (ASN93) CRYSTAL STRUCTURE OF THE RPH1 CATALYTIC CORE WITH A-KETOGLUTARATE | RPH1, HISTONE DEMETHYLASE, CATALYTIC CORE, OXIDOREDUCTASE
5he0:A (GLN598) to (GLN633) BOVINE GRK2 IN COMPLEX WITH GBETAGAMMA SUBUNITS AND CCG215022 | RGS, KINASE, PH, WD-40, INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5hej:B (GLU159) to (PRO201) PENTAMERIC LIGAND-GATED ION CHANNEL ELIC MUTANT F116A | PENTAMERIC LIGAND-GATED ION CHANNELS, MEMBRANE PROTEIN, LIGAND-GATED ION CHANNEL, TRANSPORT PROTEIN
5hej:G (GLU159) to (PRO201) PENTAMERIC LIGAND-GATED ION CHANNEL ELIC MUTANT F116A | PENTAMERIC LIGAND-GATED ION CHANNELS, MEMBRANE PROTEIN, LIGAND-GATED ION CHANNEL, TRANSPORT PROTEIN
3ox7:U (GLY197) to (THR229) THE CRYSTAL STRUCTURE OF UPA COMPLEX WITH PEPTIDE INHIBITOR MH027 AT PH4.6 | UROKINASE-TYPE PLASMINOGEN ACTIVATOR, PEPTIDYL INHIBITOR, PHARMACOPHORE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5heu:B (GLU159) to (PRO201) PENTAMERIC LIGAND-GATED ION CHANNEL ELIC MUTANT A257Y | PENTAMERIC LIGAND-GATED ION CHANNELS, MEMBRANE PROTEIN, LIGAND-GATED ION CHANNEL, TRANSPORT PROTEIN
5heu:D (GLU159) to (PRO201) PENTAMERIC LIGAND-GATED ION CHANNEL ELIC MUTANT A257Y | PENTAMERIC LIGAND-GATED ION CHANNELS, MEMBRANE PROTEIN, LIGAND-GATED ION CHANNEL, TRANSPORT PROTEIN
3oy6:U (GLY197) to (THR229) THE CRYSTAL STRUCTURE OF UPA COMPLEX WITH PEPTIDE INHIBITOR MH036 AT PH4.6 | UROKINASE-TYPE PLASMINOGEN ACTIVATOR, PEPTIDYL INHIBITOR, PHARMACOPHORE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3oyp:A (GLY140) to (ILE170) HCV NS3/4A IN COMPLEX WITH LIGAND 3 | SERINE PROTEASE, NS3, NS4A, HEPATITIS C VIRUS, PROTEASE INHIBITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3oyp:B (GLY140) to (ILE170) HCV NS3/4A IN COMPLEX WITH LIGAND 3 | SERINE PROTEASE, NS3, NS4A, HEPATITIS C VIRUS, PROTEASE INHIBITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ozo:A (GLY291) to (LEU334) CRYSTAL STRUCTURE OF INSECT BETA-N-ACETYL-D-HEXOSAMINIDASE OFHEX1 COMPLEXED WITH NGT | BETA-N-ACETYL-D-HEXOSAMINIDASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ozp:A (GLY291) to (LEU334) CRYSTAL STRUCTURE OF INSECT BETA-N-ACETYL-D-HEXOSAMINIDASE OFHEX1 COMPLEXED WITH PUGNAC | BETA-N-ACETYL-D-HEXOSAMINIDASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4dip:G (GLN73) to (ASN136) CRYSTAL STRUCTURE OF HUMAN PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP14 | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, PEPTIDYL- PROLYL CIS-TRANS ISOMERASE, ISOMERASE
4dkq:A (GLY263) to (ASN289) CRYSTAL STRUCTURE OF CLADE A/E 93TH057 HIV-1 GP120 CORE IN COMPLEX WITH DMJ-I-228 | HIV-1 GP120, CLADE A/E, CD4 MIMIC, DMJ-I-228, VIRAL PROTEIN-INHIBITOR COMPLEX
4dkr:A (GLY263) to (LEU288) CRYSTAL STRUCTURE OF CLADE A/E 93TH057 HIV-1 GP120 CORE IN COMPLEX WITH AWS-I-169 | HIV-1 GP120, CLADE A/E, CD4 MIMIC, AWS-I-169, VIRAL PROTEIN-INHIBITOR COMPLEX
4dkv:A (GLY263) to (ASN289) CRYSTAL STRUCTURE OF CLADE A/E 93TH057 HIV-1 GP120 CORE IN COMPLEX WITH NBD-10007 | HIV-1 GP120, CLADE A/E, CD4 MIMIC, NBD-10007, HYDROLASE
3dzw:A (ILE72) to (THR99) STRUCTURE OF NARCISSUS PSEUDONARCISSUS LECTIN COMPLEX WITH MANNOBIOSE AT 1.7 A RESOLUTION, FORM II | LECTIN, AGGLUTININ, MANNOBIOSE, MANNOSE-ALPHA1, 3-MANNOSE, DAFFODIL, SUGAR BINDING PROTEIN
3dzw:B (ILE72) to (THR99) STRUCTURE OF NARCISSUS PSEUDONARCISSUS LECTIN COMPLEX WITH MANNOBIOSE AT 1.7 A RESOLUTION, FORM II | LECTIN, AGGLUTININ, MANNOBIOSE, MANNOSE-ALPHA1, 3-MANNOSE, DAFFODIL, SUGAR BINDING PROTEIN
5hm2:D (ASP53) to (LEU90) CRYSTAL STRUCTURE OF THE 3C PROTEASE FROM SOUTH AFRICAN TERRITORIES TYPE 2 FOOT-AND-MOUTH DISEASE VIRUS | PICORNAVIRUS, 3C PROTEASE, TRYPSIN-LIKE PROTEASE, HYDROLASE
3p6l:A (ILE209) to (ILE230) CRYSTAL STRUCTURE OF A SUGAR PHOSPHATE ISOMERASE/EPIMERASE (BDI_1903) FROM PARABACTEROIDES DISTASONIS ATCC 8503 AT 1.85 A RESOLUTION | TIM BARREL, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, ISOMERASE
3p8n:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3/NS4A PROTEASE COMPLEXED WITH BI 201335 | HEPATITIS C VIRUS, NS3, NS4A, HALOGEN BOND, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3p8n:B (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3/NS4A PROTEASE COMPLEXED WITH BI 201335 | HEPATITIS C VIRUS, NS3, NS4A, HALOGEN BOND, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3p8o:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3/NS4A PROTEASE COMPLEXED WITH DES-BROMINE ANALOGUE OF BI 201335 | HEPATITIS C VIRUS, NS3, NS4A, HALOGEN BOND, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3p8o:B (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3/NS4A PROTEASE COMPLEXED WITH DES-BROMINE ANALOGUE OF BI 201335 | HEPATITIS C VIRUS, NS3, NS4A, HALOGEN BOND, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3pca:F (GLY119) to (ARG142) STRUCTURE OF PROTOCATECHUATE 3,4-DIOXYGENASE COMPLEXED WITH 3,4- DIHYDROXYBENZOATE | DIOXYGENASE, IRON, NONHEME, METALLOPROTEIN, OXIDOREDUCTASE, SUBSTRATE COMPLEX
5hwv:A (ARG121) to (ASN149) CRYSTAL STRUCTURE OF PAS1 COMPLEXED WITH TOLUENE | PAS, TWO-COMPONENT SIGNAL TRANSDUCTION, TOLUENE, TRANSFERASE
3pcm:F (GLY119) to (ARG142) STRUCTURE OF PROTOCATECHUATE 3,4-DIOXYGENASE COMPLEXED WITH 6- HYDROXYNICOTINIC ACID N-OXIDE AND CYANIDE | DIOXYGENASE, IRON, NONHEME, METALLOPROTEIN, OXIDOREDUCTASE, TRANSITION-STATE ANALOG COMPLEX
3pf2:A (THR472) to (ASN516) THE CRYSTAL STRUCTURE OF THE MAJOR PILIN GBS80 OF STREPTOCOCCUS AGALACTIAE 35KDA C-TERMINAL FRAGMENT | PILUS SHAFT COMPONENT, IGG-DEV FOLD, IGG-REV FOLD, CNA A TYPE, CNA B TYPE, IG-LIKE FOLD, MAJOR PILIN, BACKBONE PILIN, PILUS SUBUNIT, MAJOR PILIN GBS80, ISOPEPTIDE BOND FORMATION, GRAM-POSITIVE BACTERIAL CELL SURFACE, GBS80, CELL ADHESION
3pg2:A (THR472) to (ASN516) THE CRYSTAL STRUCTURE OF THE MAJOR PILIN GBS80 OF STREPTOCOCCUS AGALACTIAE 35 KDA C-TERMINAL FRAGMENT | IG-LIKE FOLD, MAJOR PILIN, GROUP B STREPTOCOCCUS, GBS PILI, BACKBONE PILIN, ISOPEPTIDE BOND, IGG-DEV FOLD, IGG-REV FOLD, CNA A TYPE, CNA B TYPE, GBS, GBS80, PILUS SHAFT COMPONENT, ISOPEPTIDE FORMATION, GRAM-POSITIVE BACTERIAL (GROUP B STREPTOCOCCUS) CELL SURFACE, CELL ADHESION, STRUCTURAL PROTEIN
4uhv:B (HIS283) to (VAL317) THE STRUCTURE OF VGRG1, THE NEEDLE TIP OF THE BACTERIAL TYPE VI SECRETION SYSTEM | STRUCTURAL PROTEIN, VGRG1, VIRULENCE, TOXIN, EFFECTOR, PUNCTURING DEVICE, SPIKE, T6SS, P. AERUGINOSA
4dvs:A (GLY263) to (ASN289) CRYSTAL STRUCTURE OF CLADE A/E 93TH057 HIV-1 GP120 CORE IN COMPLEX WITH NBD-557 | HIV-1 GP120, SMALL MOLECULE INHIBITOR, CD4 BINDING SITE, NBD-557, VIRAL PROTEIN-TRANSCRIPTION INHIBITOR COMPLEX
4dvt:A (GLY263) to (ASN289) CRYSTAL STRUCTURE OF CLADE A/E 93TH057 HIV-1 GP120 CORE IN COMPLEX WITH AS-II-37 | HIV-1 GP120, SMALL MOLECULE INHIBITOR, CD4 BINDING SITE, AS-II-37, VIRAL PROTEIN-TRANSCRIPTION INHIBITOR COMPLEX
4dvv:A (GLY263) to (ASN289) CRYSTAL STRUCTURE OF CLADE A/E 93TH057 HIV-1 GP120 CORE IN COMPLEX WITH AS-I-261 | HIV-1 GP120, SMALL MOLECULE INHIBITOR, CD4 BINDING SITE, AS-I-261, VIRAL PROTEIN-TRANSCRIPTION INHIBITOR COMPLEX
4dvw:A (GLY263) to (ASN289) CRYSTAL STRUCTURE OF CLADE A/E 93TH057 HIV-1 GP120 CORE IN COMPLEX WITH MAE-II-167 | HIV-1 GP120, SMALL MOLECULE INHIBITOR, CD4 BINDING SITE, MAE-II-167, VIRAL PROTEIN-TRANSCRIPTION INHIBITOR COMPLEX
3pif:C (VAL928) to (SER958) CRYSTAL STRUCTURE OF THE 5'->3' EXORIBONUCLEASE XRN1, E178Q MUTANT IN COMPLEX WITH MANGANESE | BETA BERREL, TUDOR DOMAIN, CHROMO DOMAIN, MRNA TURNOVER, RRNA PROCESSING, RNA BINDING, DNA BINDING, HYDROLASE
4dza:A (VAL310) to (GLY343) CRYSTAL STRUCTURE OF A LYSINE RACEMASE WITHIN INTERNAL ALDIMINE LINKAGE | ISOMERASE, PLP BINDING, RACEMIZATION
4e0f:C (GLY141) to (ILE165) CRYSTALLOGRAPHIC STRUCTURE OF TRIMERIC RIBOFLAVIN SYNTHASE FROM BRUCELLA ABORTUS IN COMPLEX WITH RIBOFLAVIN | BETA BARREL, ALPHA + BETA PROTEIN, RIBOFLAVIN BIOSYNTHESIS, TRANSFERASE
3pop:D (PRO7) to (GLU33) THE CRYSTAL STRUCTURE OF GILR, AN OXIDOREDUCTASE THAT CATALYZES THE TERMINAL STEP OF GILVOCARCIN BIOSYNTHESIS | FAD BINDING PROTEIN, GILVOCARCIN, GILVOCARCIN BIOSYNTHESIS, COVALENTLY BOUND FAD, OXIDOREDUCTASE
3pqb:A (PRO7) to (GLU33) THE CRYSTAL STRUCTURE OF PREGILVOCARCIN IN COMPLEX WITH GILR, AN OXIDOREDUCTASE THAT CATALYZES THE TERMINAL STEP OF GILVOCARCIN BIOSYNTHESIS | OXIDOREDUCTASE, FAD BINDING PROTEIN, COVALENTLY BOUND FAD
3pqb:B (PRO7) to (GLU33) THE CRYSTAL STRUCTURE OF PREGILVOCARCIN IN COMPLEX WITH GILR, AN OXIDOREDUCTASE THAT CATALYZES THE TERMINAL STEP OF GILVOCARCIN BIOSYNTHESIS | OXIDOREDUCTASE, FAD BINDING PROTEIN, COVALENTLY BOUND FAD
3pqb:C (PRO7) to (GLU33) THE CRYSTAL STRUCTURE OF PREGILVOCARCIN IN COMPLEX WITH GILR, AN OXIDOREDUCTASE THAT CATALYZES THE TERMINAL STEP OF GILVOCARCIN BIOSYNTHESIS | OXIDOREDUCTASE, FAD BINDING PROTEIN, COVALENTLY BOUND FAD
3pqb:D (PRO7) to (GLU33) THE CRYSTAL STRUCTURE OF PREGILVOCARCIN IN COMPLEX WITH GILR, AN OXIDOREDUCTASE THAT CATALYZES THE TERMINAL STEP OF GILVOCARCIN BIOSYNTHESIS | OXIDOREDUCTASE, FAD BINDING PROTEIN, COVALENTLY BOUND FAD
5ifi:B (TYR536) to (SER555) CRYSTAL STRUCTURE OF ACETYL-COA SYNTHETASE IN COMPLEX WITH ADENOSINE- 5'-PROPYLPHOSPHATE FROM CRYPTOCOCCUS NEOFORMANS H99 | SSGCID, NIH, NIAID, SBRI, UW, BERYLLIUM, SYNTHETASE, ACS1, PRX, PROPYL-AMP, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, LIGASE
3pro:B (GLY152) to (GLU182) ALPHA-LYTIC PROTEASE COMPLEXED WITH C-TERMINAL TRUNCATED PRO REGION | PRO REGION, FOLDASE, PROTEIN FOLDING, SERINE PROTEASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4eeo:A (ASP250) to (SER293) CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH GLCNAC-BETA1,6-GLCNAC-ALPHA-BENZYL | GT-A FOLD, GLYCOSYLTANSFERASE, UDP-GALACOTSE, TRANSFERASE
4ejg:F (LEU370) to (LYS387) HUMAN CYTOCHROME P450 2A13 IN COMPLEX WITH NICOTINE | CYP2A13, CYTOCHROME P450 2A13, HEME PROTEIN, P450 2A13, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4ejj:C (LEU370) to (LYS387) HUMAN CYTOCHROME P450 2A6 IN COMPLEX WITH NICOTINE | CYTOCHROME P450 2A6, P450 2A6, HEME PROTEIN, MONOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
3q4d:A (GLN5) to (THR27) CRYSTAL STRUCTURE OF DIPEPTIDE EPIMERASE FROM CYTOPHAGA HUTCHINSONII COMPLEXED WITH MG AND DIPEPTIDE D-ALA-L-ALA | (BETA/ALPHA)8-BARREL, ISOMERASE
3q4d:B (GLN5) to (THR27) CRYSTAL STRUCTURE OF DIPEPTIDE EPIMERASE FROM CYTOPHAGA HUTCHINSONII COMPLEXED WITH MG AND DIPEPTIDE D-ALA-L-ALA | (BETA/ALPHA)8-BARREL, ISOMERASE
3q4d:C (GLN5) to (THR27) CRYSTAL STRUCTURE OF DIPEPTIDE EPIMERASE FROM CYTOPHAGA HUTCHINSONII COMPLEXED WITH MG AND DIPEPTIDE D-ALA-L-ALA | (BETA/ALPHA)8-BARREL, ISOMERASE
3q4d:D (GLN5) to (THR27) CRYSTAL STRUCTURE OF DIPEPTIDE EPIMERASE FROM CYTOPHAGA HUTCHINSONII COMPLEXED WITH MG AND DIPEPTIDE D-ALA-L-ALA | (BETA/ALPHA)8-BARREL, ISOMERASE
3q4d:E (GLN5) to (THR27) CRYSTAL STRUCTURE OF DIPEPTIDE EPIMERASE FROM CYTOPHAGA HUTCHINSONII COMPLEXED WITH MG AND DIPEPTIDE D-ALA-L-ALA | (BETA/ALPHA)8-BARREL, ISOMERASE
3q4d:F (GLN5) to (THR27) CRYSTAL STRUCTURE OF DIPEPTIDE EPIMERASE FROM CYTOPHAGA HUTCHINSONII COMPLEXED WITH MG AND DIPEPTIDE D-ALA-L-ALA | (BETA/ALPHA)8-BARREL, ISOMERASE
3q4d:G (GLN5) to (THR27) CRYSTAL STRUCTURE OF DIPEPTIDE EPIMERASE FROM CYTOPHAGA HUTCHINSONII COMPLEXED WITH MG AND DIPEPTIDE D-ALA-L-ALA | (BETA/ALPHA)8-BARREL, ISOMERASE
3q4d:H (GLN5) to (THR27) CRYSTAL STRUCTURE OF DIPEPTIDE EPIMERASE FROM CYTOPHAGA HUTCHINSONII COMPLEXED WITH MG AND DIPEPTIDE D-ALA-L-ALA | (BETA/ALPHA)8-BARREL, ISOMERASE
3q4d:I (GLN5) to (THR27) CRYSTAL STRUCTURE OF DIPEPTIDE EPIMERASE FROM CYTOPHAGA HUTCHINSONII COMPLEXED WITH MG AND DIPEPTIDE D-ALA-L-ALA | (BETA/ALPHA)8-BARREL, ISOMERASE
3q76:A (SER197) to (ALA229) STRUCTURE OF HUMAN NEUTROPHIL ELASTASE (UNCOMPLEXED) | TRYPSIN FAMILY FOLD, PROTEASE, HYDROLASE
3q77:A (SER197) to (ALA229) STRUCTURE OF HUMAN NEUTROPHIL ELASTASE IN COMPLEX WITH A DIHYDROPYRIMIDONE INHIBITOR | TRYPSIN FAMILY FOLD, PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4est:E (GLY197) to (THR229) CRYSTAL STRUCTURE OF THE COVALENT COMPLEX FORMED BY A PEPTIDYL ALPHA, ALPHA-DIFLUORO-BETA-KETO AMIDE WITH PORCINE PANCREATIC ELASTASE AT 1.78-ANGSTROMS RESOLUTION | SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4f4o:F (LEU162) to (LYS192) STRUCTURE OF THE HAPTOGLOBIN-HAEMOGLOBIN COMPLEX | GLOBIN FOLD, SERINE PROTEASE FOLD, COMPLEMENT CONTROL PROTEIN, HAEMOGLOBIN SCAVENGING, OXYGEN STORAGE-TRANSPORT COMPLEX, OXYGEN TRANSPORT-TRANSPORT PROTEIN COMPLEX
5j7o:A (SER242) to (ASN267) FAUSTOVIRUS MAJOR CAPSID PROTEIN | VIRUS, CAPSID, DOUBLE JELLY-ROLL, VIRAL PROTEIN
5j7v:A (SER242) to (ASN267) FAUSTOVIRUS MAJOR CAPSID PROTEIN | VIRUS, DOUBLE JELLY-ROLL
4uxj:H (GLU131) to (CYS173) LEISHMANIA MAJOR THYMIDINE KINASE IN COMPLEX WITH DTTP | TRANSFERASE
4uy7:A (ARG249) to (ALA274) CRYSTAL STRUCTURE OF HISTIDINE BOUND HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD FROM MYCOBACTERIUM SMEGMATIS | TRANSFERASE, ANTIOXIDANT
3qt1:B (GLY902) to (LEU941) RNA POLYMERASE II VARIANT CONTAINING A CHIMERIC RPB9-C11 SUBUNIT | TRANSFERASE-TRANSCRIPTION COMPLEX, RNA POLYMERASE II, TRANSCRIPTION, ELONGATION, MRNA CLEAVAGE, TRANSFERASE
4fft:B (MET32) to (TYR68) CRYSTAL STRUCTURE OF BACILLUS SUBTILIS EXPANSIN (EXLX1) IN COMPLEX WITH MIXED-LINKAGE GLUCAN | CELLULOSE, CELLULOSE-BINDING PROTEIN
3qz1:D (PRO363) to (GLU379) CRYSTAL STRUCTURE OF BOVINE STEROID OF 21-HYDROXYLASE (P450C21) | P450 MONOOXYGENASE, 21-HYDROXYLASE, OXIDOREDUCTASE
3r0u:A (ASP7) to (ASN29) CRYSTAL STRUCTURE OF NYSGRC ENOLASE TARGET 200555, A PUTATIVE DIPEPTIDE EPIMERASE FROM FRANCISELLA PHILOMIRAGIA : TARTRATE AND MG COMPLEX | ENOLASE, STRUCTURAL GENOMICS, PUTATIVE EPIMERASE, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, LYASE
3r10:A (ASP7) to (ASN29) CRYSTAL STRUCTURE OF NYSGRC ENOLASE TARGET 200555, A PUTATIVE DIPEPTIDE EPIMERASE FROM FRANCISELLA PHILOMIRAGIA : MG COMPLEX | ENOLASE, STRUCTURAL GENOMICS, PUTATIVE EPIMERASE, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, LYASE
4w8o:A (GLY401) to (GLU425) STRUCTURE OF THE LUCIFERASE-LIKE ENZYME FROM THE NONLUMINESCENT ZOPHOBAS MORIO MEALWORM | LUCIFERASE-LIKE ENZYME, OXIDOREDUCTASE
4w8w:C (THR135) to (LEU156) CRYSTAL STRUCTURE OF OLIGOMERIC CMR4 FROM PYROCOCCUS FURIOSUS | CMR4, CMR COMPLEX, OLIGOMERIC, CRIPSR, HYDROLASE
4fmj:I (PRO275) to (LYS319) MERKEL CELL POLYOMAVIRUS VP1 IN COMPLEX WITH GD1A OLIGOSACCHARIDE | VIRAL CAPSID PROTEIN, JELLY ROLL, ENCAPSIDATION, RECEPTOR BINDING, SIALYLATED OLIGOSACCHARIDES, VIRAL PROTEIN
4fmj:Q (GLY274) to (LYS319) MERKEL CELL POLYOMAVIRUS VP1 IN COMPLEX WITH GD1A OLIGOSACCHARIDE | VIRAL CAPSID PROTEIN, JELLY ROLL, ENCAPSIDATION, RECEPTOR BINDING, SIALYLATED OLIGOSACCHARIDES, VIRAL PROTEIN
4fn5:A (PRO486) to (ALA524) ELONGATION FACTOR G 1 (PSEUDOMONAS AERUGINOSA) IN COMPLEX WITH ARGYRIN B | ELONGATION FACTOR, TRANSLATION, TRANSLATION-ANTIBIOTIC COMPLEX
3rc5:A (GLY1140) to (ILE1170) MOLECULAR MECHANISMS OF VIRAL AND HOST-CELL SUBSTRATE RECOGNITION BY HCV NS3/4A PROTEASE | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3rc4:A (GLY1140) to (ILE1170) MOLECULAR MECHANISMS OF VIRAL AND HOST-CELL SUBSTRATE RECOGNITION BY HCV NS3/4A PROTEASE | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, SERINE PROTEASE, HYDROLASE, CHYMOTRYPSIN-LIKE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3rc6:A (GLY1140) to (ILE1170) MOLECULAR MECHANISMS OF VIRAL AND HOST-CELL SUBSTRATE RECOGNITION BY HCV NS3/4A PROTEASE | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, SERINE PROTEASE, VIRAL PROTEIN, HYDROLASE
5jpm:J (ARG646) to (THR670) STRUCTURE OF THE COMPLEX OF HUMAN COMPLEMENT C4 WITH MASP-2 REBUILT USING IMDFF | COMPLEMENT, IMMUNE SYSTEM, BLOOD
4fw9:A (PRO265) to (ALA301) CRYSTAL STRUCTURE OF THE LON-LIKE PROTEASE MTALONC | LON PROTEASE, HYDROLASE
4fwd:A (PRO265) to (ALA301) CRYSTAL STRUCTURE OF THE LON-LIKE PROTEASE MTALONC IN COMPLEX WITH BORTEZOMIB | LON PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4fwg:A (PRO265) to (ALA301) CRYSTAL STRUCTURE OF THE LON-LIKE PROTEASE MTALONC IN COMPLEX WITH LACTACYSTIN | LON PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4fxu:B (GLY141) to (ILE165) CRYSTALLOGRAPHIC STRUCTURE OF TRIMERIC RIBOFLAVIN SYNTHASE FROM BRUCELLA ABORTUS | BETA BARREL, ALPHA + BETA PROTEIN, RIBOFLAVIN BIOSYNTHESIS, TRANSFERASE
4fxu:C (GLY141) to (ILE165) CRYSTALLOGRAPHIC STRUCTURE OF TRIMERIC RIBOFLAVIN SYNTHASE FROM BRUCELLA ABORTUS | BETA BARREL, ALPHA + BETA PROTEIN, RIBOFLAVIN BIOSYNTHESIS, TRANSFERASE
4g36:A (ARG337) to (GLY394) PHOTINUS PYRALIS LUCIFERASE IN THE ADENYLATE-FORMING CONFORMATION BOUND TO DLSA | ANL SUPERFAMILY, LIGASE, ADENYLATING ENZYMES, LUCIFERASE, DOMAIN ALTERNATION, FIREFLY LUCIFERASE
4g6i:A (GLY141) to (ILE165) CRYSTALLOGRAPHIC STRUCTURE OF TRIMERIC RIBOFLAVIN SYNTHASE FROM BRUCELLA ABORTUS IN COMPLEX WITH ROSEOFLAVIN | TRANSFERASE, BETA BARREL, ALPHA + BETA PROTEIN, RIBOFLAVIN BIOSYNTHESIS
5k70:D (GLN1) to (CYS28) SIDEKICK-2 IMMUNOGLOBULIN DOMAINS 1-4 H18R/N22S MUTANT | CELL ADHESION, IMMUNOGLOBULIN
5knc:A (CYS28) to (GLN50) CRYSTAL STRUCTURE OF THE 3 ADP-BOUND V1 COMPLEX | P-LOOP, HYDROLASE, NA(+)-ATPASE, ATP BINDING
4gov:A (VAL264) to (THR309) THE CRYSTAL STRUCTURE OF HUMAN FASCIN 1 S39D MUTANT | BETA-TREFOIL, ACTIN BUNDLING PROTEIN, CANCER, METASTASIS, CELL MIGRATION, ACTIN-BINDING, PHOSPHOPROTEIN, PROTEIN BINDING, ACTIN
5l56:A (TRP976) to (SER1002) PLEXIN A1 FULL EXTRACELLULAR REGION, DOMAINS 1 TO 10, TO 4 ANGSTROM | RECEPTOR, SIGNALING, AXON GUIDANCE, SIGNALING PROTEIN
5l59:B (TRP976) to (SER1002) PLEXIN A1 FULL EXTRACELLULAR REGION, DOMAINS 1 TO 10, TO 6 ANGSTROM, SPACEGROUP P2(1) | RECEPTOR, SIGNALING, AXON GUIDANCE, SIGNALING PROTEIN
5l5c:A (TRP976) to (SER1002) PLEXIN A1 FULL EXTRACELLULAR REGION, DOMAINS 1 TO 10, TO 6 ANGSTROM, SPACEGROUP P4(3)2(1)2 | RECEPTOR, SIGNALING, AXON GUIDANCE, SIGNALING PROTEIN
5ljx:A (GLY187) to (HIS213) STRUCTURE OF HANTAVIRUS ENVELOPE GLYCOPROTEIN GC IN POSTFUSION CONFORMATION IN PRESENCE OF 600 MM KCL | HANTAVIRUS, GLYCOPROTEIN, VIRAL FUSION, VIRAL PROTEIN
5lk0:A (GLY187) to (PHE211) STRUCTURE OF HANTAVIRUS ENVELOPE GLYCOPROTEIN GC IN POSTFUSION CONFORMATION IN PRESENCE OF 100 MM KCL | HANTAVIRUS, GLYCOPROTEIN, VIRAL FUSION, VIRAL PROTEIN
5lk2:A (GLY187) to (HIS213) STRUCTURE OF HANTAVIRUS ENVELOPE GLYCOPROTEIN GC IN POSTFUSION CONFORMATION IN PRESENCE OF 300 MM KCL | HANTAVIRUS, GLYCOPROTEIN, VIRAL FUSION, VIRAL PROTEIN
5lk3:A (GLY187) to (HIS213) STRUCTURE OF HANTAVIRUS ENVELOPE GLYCOPROTEIN GC IN POSTFUSION CONFORMATION IN PRESENCE OF 500 MM KCL | HANTAVIRUS, GLYCOPROTEIN, VIRAL FUSION, VIRAL PROTEIN
5t12:A (PRO367) to (ASP396) N-TERMINAL DOMAIN OF ENZYME 1 - NITROGEN | PTSNTR, PHOSPHOTRANSFER, TRANSFERASE
6cha:G (ALA179) to (GLY211) STRUCTURE OF A TETRAHEDRAL TRANSITION STATE COMPLEX OF ALPHA-*CHYMOTRYPSIN AT 1.8-*ANGSTROMS RESOLUTION | HYDROLASE (SERINE PROTEINASE)
6taa:A (GLY111) to (ASP177) STRUCTURE AND MOLECULAR MODEL REFINEMENT OF ASPERGILLUS ORYZAE (TAKA) ALPHA-AMYLASE: AN APPLICATION OF THE SIMULATED-ANNEALING METHOD | HYDROLASE(O-GLYCOSYL)
7gch:G (ALA179) to (GLY211) STRUCTURE OF CHYMOTRYPSIN-*TRIFLUOROMETHYL KETONE INHIBITOR COMPLEXES. COMPARISON OF SLOWLY AND RAPIDLY EQUILIBRATING INHIBITORS | HYDROLASE (SERINE PROTEINASE)
7taa:A (GLY111) to (ASP177) FAMILY 13 ALPHA AMYLASE IN COMPLEX WITH ACARBOSE | HYDROLASE, GLYCOSYL HYDROLASE, TAKA, AMYLASE, ACARBOSE
8est:E (GLY197) to (THR229) REACTION OF PORCINE PANCREATIC ELASTASE WITH 7-SUBSTITUTED 3-ALKOXY-4-CHLOROISOCOUMARINS: DESIGN OF POTENT INHIBITORS USING THE CRYSTAL STRUCTURE OF THE COMPLEX FORMED WITH 4- CHLORO-3-ETHOXY-7-GUANIDINO-ISOCOUMARIN | HYDROLASE(SERINE PROTEINASE)
2ody:B (ARG206) to (THR229) THROMBIN-BOUND BOOPHILIN DISPLAYS A FUNCTIONAL AND ACCESSIBLE REACTIVE-SITE LOOP | KUNITZ-TYPE THROMBIN INHIBITOR, BLOOD CLOTTING-BLOOD CLOTTING INHIBITOR COMPLEX
1a6r:A (VAL269) to (LEU300) GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A | BLEOMYCIN HYDROLASE, PEPTIDASE, PROTEASE, DNA-BINDING PROTEIN, SELF- COMPARTMENTALIZING PROTEASE, HYDROLASE
2any:A (VAL65) to (LYS107) EXPRESSION, CRYSTALLIZATION AND THE THREE-DIMENSIONAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN PLASMA KALLIKREIN: IMPLICATIONS FOR STRUCTURE-BASED DESIGN OF PROTEASE INHIBITORS | MUTAGENICALLY DEGLYCOSYALTED HUMAN PLASMA KALLIKREIN PROTEASE DOMAIN; TRYPSIN-LIKE SERINE PROTEASE, BLOOD CLOTTING, HYDROLASE
1ae5:A (THR177) to (THR204) HUMAN HEPARIN BINDING PROTEIN | SERINE PROTEASE HOMOLOG, ENDOTOXIN BINDING, HEPARIN BINDING, INFLAMMATION, ANTIBACTERIAL, CAP37, AZUROCIDIN, GLYCOSYLATED PROTEIN
4wnz:A (ASP134) to (LEU156) CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS CMR4 (CAS7) | NUCLEASE, RAMP DOMAIN, CRISPR-CAS SYSTEM, CMR CMPLEX
4wnz:B (ASP134) to (LEU156) CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS CMR4 (CAS7) | NUCLEASE, RAMP DOMAIN, CRISPR-CAS SYSTEM, CMR CMPLEX
3ewy:A (LEU413) to (SER434) K314A MUTANT OF HUMAN OROTIDYL-5'-MONOPHOSPHATE DECARBOXYLASE SOAKED WITH OMP, DECARBOXYLATED TO UMP | DECARBOXYLASE, TIM BARREL, UNUSUAL CATALYSIS, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
3ewz:B (LEU413) to (SER434) HUMAN OROTIDYL-5'-MONOPHOSPHATE DECARBOXYLASE IN COMPLEX WITH 5-CYANO-UMP | DECARBOXYLASE, TIM BARREL, UNUSUAL CATALYSIS, ALTERNATIVE SPLICING, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, POLYMORPHISM, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
4hkp:B (LEU224) to (SER245) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH CMP-N3-OXIDE | ALPHA-BETA BARREL, DECARBOXYLASE, LYASE-LYASE INHIBITOR COMPLEX
2bml:A (GLY291) to (LYS318) OFLOXACIN-LIKE ANTIBIOTICS INHIBIT PNEUMOCOCCAL CELL WALL DEGRADING VIRULENCE FACTORS | CHOLINE-BINDING DOMAIN, CELL WALL ATTACHMENT, OFLOXACIN- LIKE ANTIBIOTICS
2bml:B (GLY291) to (LYS318) OFLOXACIN-LIKE ANTIBIOTICS INHIBIT PNEUMOCOCCAL CELL WALL DEGRADING VIRULENCE FACTORS | CHOLINE-BINDING DOMAIN, CELL WALL ATTACHMENT, OFLOXACIN- LIKE ANTIBIOTICS
1boq:A (GLY144) to (GLU182) PRO REGION C-TERMINUS: PROTEASE ACTIVE SITE INTERACTIONS ARE CRITICAL IN CATALYZING THE FOLDING OF ALPHA-LYTIC PROTEASE | SERINE PROTEASE, FOLDING MUTANT, HYDROLASE
4x6a:B (GLY902) to (LEU941) CRYSTAL STRUCTURE OF YEAST RNA POLYMERASE II ENCOUNTERING OXIDATIVE CYCLOPURINE DNA LESIONS | POL II ELONGATION COMPLEX OXIDATIVE CYCLOPURINE DNA LESIONS, TRANSCRIPTION-DNA COMPLEX
2pg7:D (LEU370) to (LYS387) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 N297Q/I300V | CYP2A6, P450 2A6, P450, MONOOXYGENASES, DRUG METABOLIZING ENZYME, HEME, INDOLE, MUTANT, OXIDOREDUCTASE
1c5z:B (GLY197) to (THR229) STRUCTURAL BASIS FOR SELECTIVITY OF A SMALL MOLECULE, S1- BINDING, SUB-MICROMOLAR INHIBITOR OF UROKINASE TYPE PLASMINOGEN ACTIVATOR | SELECTIVE, S1 SITE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, UROKINASE, TRYPSIN, THROMBIN, BLOOD CLOTTING
1cbw:H (ALA179) to (GLY211) BOVINE CHYMOTRYPSIN COMPLEXED TO BPTI | SERINE PROTEASE, INHIBITOR, PROTEASE-SUBSTRATE INTERACTIONS, COMPLEX (SERINE PROTEASE/INHIBITOR)
2py7:X (GLY227) to (GLY248) CRYSTAL STRUCTURE OF E. COLI PHOSPHOENOLPYRUVATE CARBOXYKINASE MUTANT LYS213SER COMPLEXED WITH ATP-MG2+-MN2+ | PHOSPHOENOLPYRUVATE CARBOXYKINASE, ACTIVE SITE LYSINE, TETRAHEDRAL MANGANESE COORDINATION, LYASE
2qcf:A (LEU413) to (SER434) CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN (ASP312ASN MUTANT) OF HUMAN UMP SYNTHASE BOUND TO 5-FLUORO-UMP | UMP SYNTHASE, DECARBOXYLASE, CATALYTIC PROFICIENCY, LYASE
2qcn:A (LEU413) to (SER434) COVALENT COMPLEX OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE WITH 6-IODO-UMP | UMP SYNTHASE, DECARBOXYLASE, CATALYTIC PROFICIENCY, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
1phh:A (ASP68) to (ASP87) CRYSTAL STRUCTURE OF P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH ITS REACTION PRODUCT 3,4-DIHYDROXYBENZOATE | OXIDOREDUCTASE
1pjp:A (GLY197) to (THR229) THE 2.2 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH SUCCINYL- ALA-ALA-PRO-PHE-CHLOROMETHYLKETONE | HUMAN CHYMASE, SERINE PROTEINASE, DIPEPTIDYL CARBOXYPEPTIDASE, ANGIOTENSIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4xvs:G (GLY263) to (LEU288) CRYSTAL STRUCTURE OF HIV-1 DONOR 45 D45-01DG5 COREE GP120 WITH ANTIBODY 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 (VRC07_1995) | HIV-1 ANTIBODYOMICS NEUTRALIZING ANTIBODY GERMLINE BINDING, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
4xvt:G (GLY263) to (LEU288) CRYSTAL STRUCTURE OF HIV-1 93TH057 COREE GP120 WITH ANTIBODY 45- VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 (VRC07_1995) | HIV-1 ANTIBODYOMICS NEUTRALIZING ANTIBODY GERMLINE BINDING, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
3t3r:B (LEU370) to (LYS387) HUMAN CYTOCHROME P450 2A6 IN COMPLEX WITH PILOCARPINE | CYP2A6, CYTOCHROME P450 2A6, P450 2A6, HEME PROTEIN, MONOOXYGENASE, DRUG METABOLISM, XENOBIOTIC METABOLISM, ENDOPLASMIC RETICULUM, MEMBRANE, OXIDOREDUCTASE
4iut:B (LEU201) to (ARG237) CRYSTAL STRUCTURE OF SHH1 SAWADEE DOMAIN IN COMPLEX WITH H3K9ME2 PEPTIDE | TANDEM TUDOR, ZINC FINGER, H3K9ME2, MEDIATE INTERACTION, HISTONE, METHYLATION, GENE REGULATION
1ds2:E (GLY196) to (GLN229) CRYSTAL STRUCTURE OF SGPB:OMTKY3-COO-LEU18I | SERINE PROTEINASE, PROTEIN INHIBITOR, OVOMUCOID, CANONICAL INHIBITOR, ESTER BOND, SGPB, OMTKY3, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4iw4:C (LYS94) to (GLU134) CRYSTAL STRUCTURE OF THE SERINE PROTEASE DOMAIN OF MASP-3 IN COMPLEX WITH ECOTIN | TRYPSIN-LIKE FOLD, PROTEASE, INHIBITOR, EXTRACELLULAR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
1dy9:A (GLY140) to (ILE170) INHIBITION OF THE HEPATITIS C VIRUS NS3/4A PROTEASE. THE CRYSTAL STRUCTURES OF TWO PROTEASE-INHIBITOR COMPLEXES (INHIBITOR I) | SERINE PROTEASE, NS3, NS4A, HEPATITIS C VIRUS, PROTEASE INHIBITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1dy9:B (GLY140) to (ILE170) INHIBITION OF THE HEPATITIS C VIRUS NS3/4A PROTEASE. THE CRYSTAL STRUCTURES OF TWO PROTEASE-INHIBITOR COMPLEXES (INHIBITOR I) | SERINE PROTEASE, NS3, NS4A, HEPATITIS C VIRUS, PROTEASE INHIBITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2qvy:X (THR394) to (SER415) 4-CHLOROBENZOYL-COA LIGASE/SYNTHETASE, I303G MUTATION, BOUND TO 3,4- DICHLOROBENZOATE | ADENYLATE-FORMING ENZYMES, ACYL-COA LIGASE, LIGASE
2qw0:X (THR394) to (PRO414) 4-CHLOROBENZOYL-COA LIGASE/SYNTHETASE, I303A MUTATION, BOUND TO 3,4 DICHLOROBENZOATE | ADENYLATE-FORMING ENZYMES, ACYL-COA LIGASE, LIGASE
4j2g:B (LEU76) to (CYS106) ATG13 HORMA DOMAIN | AUTOPHAGY, HORMA, ATG13, UNKNOWN FUNCTION
2r5j:L (LEU42) to (GLY67) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 35 | HPV35, CAPSID, PENTAMER, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID PROTEIN, LATE PROTEIN, VIRION, VIRAL PROTEIN
2r5j:O (LEU42) to (GLY67) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 35 | HPV35, CAPSID, PENTAMER, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID PROTEIN, LATE PROTEIN, VIRION, VIRAL PROTEIN
1elb:A (GLY205) to (THR239) ANALOGOUS INHIBITORS OF ELASTASE DO NOT ALWAYS BIND ANALOGOUSLY | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, SERINE PROTEINASE
2dyi:A (LEU97) to (ARG124) CRYSTAL STRUCTURE OF 16S RIBOSOMAL RNA PROCESSING PROTEIN RIMM FROM THERMUS THERMOPHILUS HB8 | RIBOSOMAL PROTEIN S19, 16S RRNA PROCESSING, PRC-BARREL, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, RIBOSOME
1esb:A (GLY205) to (THR239) DIRECT STRUCTURE OBSERVATION OF AN ACYL-ENZYME INTERMEDIATE IN THE HYDROLYSIS OF AN ESTER SUBSTRATE BY ELASTASE | HYDROLASE, SERINE PROTEINASE
2e1r:A (PRO559) to (PRO592) STRUCTURE OF EEF2 IN COMPLEX WITH A SORDARIN DERIVATIVE | PROTEIN-LIGAND COMPLEX, G-PROTEIN, TRANSLATION
1evi:A (GLY277) to (TYR309) THREE-DIMENSIONAL STRUCTURE OF THE PURPLE INTERMEDIATE OF PORCINE KIDNEY D-AMINO ACID OXIDASE | FLAVOENZYME, OXIDOREDUCTASE
1evi:B (GLY277) to (TYR309) THREE-DIMENSIONAL STRUCTURE OF THE PURPLE INTERMEDIATE OF PORCINE KIDNEY D-AMINO ACID OXIDASE | FLAVOENZYME, OXIDOREDUCTASE
4jo2:L (ASP77) to (ASP109) CRYSTAL STRUCTURE OF RABBIT MAB R56 FAB IN COMPLEX WITH V3 CROWN OF HIV-1 CONSENSUS A GP120 | IG, ANTIBODY, IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX
4joi:B (PHE23) to (GLN56) CRYSTAL STRUCTURE OF THE HUMAN TELOMERIC STN1-TEN1 COMPLEX | OB FOLD, DNA BINDING PROTEIN
2sgp:E (GLY196) to (GLN229) PRO 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5 | COMPLEX (SERINE PROTEASE/INHIBITOR), SERINE PROTEINASE, PROTEIN INHIBITOR, HYDROLASE/INHIBITOR COMPLEX
4jpw:G (GLY263) to (ASN289) CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY 12A21 IN COMPLEX WITH HIV-1 STRAIN 93TH057 GP120 MUTANT | HIV, GP120, CD4-BINDING SITE, 12A21, NEUTRALIZATION, VACCINE, ANTIBODY, ENVELOPE PROTEIN, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
2tod:A (VAL335) to (VAL367) ORNITHINE DECARBOXYLASE FROM TRYPANOSOMA BRUCEI K69A MUTANT IN COMPLEX WITH ALPHA-DIFLUOROMETHYLORNITHINE | POLYAMINE METABOLISM, PYRIDOXAL 5'-PHOSPHATE, ALPHA-BETA BARREL, LYASE
2tod:B (VAL335) to (VAL367) ORNITHINE DECARBOXYLASE FROM TRYPANOSOMA BRUCEI K69A MUTANT IN COMPLEX WITH ALPHA-DIFLUOROMETHYLORNITHINE | POLYAMINE METABOLISM, PYRIDOXAL 5'-PHOSPHATE, ALPHA-BETA BARREL, LYASE
2tod:C (VAL335) to (VAL367) ORNITHINE DECARBOXYLASE FROM TRYPANOSOMA BRUCEI K69A MUTANT IN COMPLEX WITH ALPHA-DIFLUOROMETHYLORNITHINE | POLYAMINE METABOLISM, PYRIDOXAL 5'-PHOSPHATE, ALPHA-BETA BARREL, LYASE
2eaw:A (LEU224) to (SER245) HUMAN UMP SYNTHASE (C-TERMINAL DOMAIN- OROTIDINE 5'- MONOPHOSPHATE DECARBOXYLASE) | UMP SYNTHASE, C-TERMINAL DOMAIN, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, HUMAN, LYASE
1fgt:A (GLY77) to (LYS110) LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q697N MUTANT | DIOXYGENASE, LIPOXYGENASE, METALLOPROTEIN, FATTY ACIDS, OXIDOREDUCTASE
4k1t:C (ASP48) to (GLU84) GLY-SER-SPLB PROTEASE FROM STAPHYLOCOCCUS AUREUS AT 1.60 A RESOLUTION | CHYMOTRYPSIN-LIKE FOLD, SERINE PROTEASE, EXTRACELLULAR, HYDROLASE
4k2y:A (GLY197) to (THR229) CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH FRAGMENT INHIBITOR 6-CHLORO-1,3-DIHYDRO-2H-INDOL-2-ONE | SERINE PROTEASE, GLYCOSYLATED, MAST CELLS, SECRETED, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
1fnu:A (PRO29) to (GLU61) STRUCTURE OF STREPTOCOCCAL PYROGENIC EXOTOXIN A | SUPERANTIGEN, EXOTOXIN A
1fnu:B (PRO329) to (GLU361) STRUCTURE OF STREPTOCOCCAL PYROGENIC EXOTOXIN A | SUPERANTIGEN, EXOTOXIN A
1fnu:C (PRO629) to (GLU661) STRUCTURE OF STREPTOCOCCAL PYROGENIC EXOTOXIN A | SUPERANTIGEN, EXOTOXIN A
1fnu:D (PRO929) to (GLU961) STRUCTURE OF STREPTOCOCCAL PYROGENIC EXOTOXIN A | SUPERANTIGEN, EXOTOXIN A
3hm7:C (ASP5) to (ARG21) CRYSTAL STRUCTURE OF ALLANTOINASE FROM BACILLUS HALODURANS C-125 | ALLANTOINASE, METALLO-DEPENDENT HYDROLASE, PROTEIN STRUCTURE INITIATIVE, PSI-2, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, STRUCTURAL GENOMICS, DNA-BINDING, HYDROLASE, METAL-BINDING, PURINE METABOLISM, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
1rgq:A (GLY143) to (ILE173) M9A HCV PROTEASE COMPLEX WITH PENTAPEPTIDE KETO-AMIDE INHIBITOR | HEPATITIS C VIRUS PROTEASE KETO AMIDE PEPTIDE INHIBITOR, VIRAL PROTEIN, HYDROLASE
2vbc:A (SER137) to (ILE165) CRYSTAL STRUCTURE OF THE NS3 PROTEASE-HELICASE FROM DENGUE VIRUS | TRANSMEMBRANE, RNA REPLICATION, NS2B-NS3 PROTEASE, NS3 BIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, HYDROLASE
2f8h:A (LEU73) to (LEU99) STRUCTURE OF ACETYLCITRULLINE DEACETYLASE FROM XANTHOMONAS CAMPESTRIS IN METAL-FREE FORM | ALPHA/BETA, HYDROLASE
2f9u:A (GLY140) to (ILE170) HCV NS3 PROTEASE DOMAIN WITH NS4A PEPTIDE AND A KETOAMIDE INHIBITOR WITH A P2 NORBORANE | HCV, HEPATITIS C PROTEASE, NS3 PROTEASE, KETOAMIDE INHIBITOR, VIRAL PROTEIN
2f9u:C (GLY140) to (ILE170) HCV NS3 PROTEASE DOMAIN WITH NS4A PEPTIDE AND A KETOAMIDE INHIBITOR WITH A P2 NORBORANE | HCV, HEPATITIS C PROTEASE, NS3 PROTEASE, KETOAMIDE INHIBITOR, VIRAL PROTEIN
2fdy:C (LEU370) to (LYS387) MICROSOMAL P450 2A6 WITH THE INHIBITOR ADRITHIOL BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
2fdy:D (LEU370) to (LYS387) MICROSOMAL P450 2A6 WITH THE INHIBITOR ADRITHIOL BOUND | CYP2A6, P450 2A6, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, COUMARIN 7-HYDROXYLASE, NICOTINE OXIDASE, OXIDOREDUCTASE
3uq4:A (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F247L (F16L) | MEMBRANE PROTEIN, LIGANDED-GATED ION CHANNEL, TRANSPORT PROTEIN
3uq4:B (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F247L (F16L) | MEMBRANE PROTEIN, LIGANDED-GATED ION CHANNEL, TRANSPORT PROTEIN
3uq4:C (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F247L (F16L) | MEMBRANE PROTEIN, LIGANDED-GATED ION CHANNEL, TRANSPORT PROTEIN
3uq4:D (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F247L (F16L) | MEMBRANE PROTEIN, LIGANDED-GATED ION CHANNEL, TRANSPORT PROTEIN
3uq4:E (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F247L (F16L) | MEMBRANE PROTEIN, LIGANDED-GATED ION CHANNEL, TRANSPORT PROTEIN
3uq4:F (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F247L (F16L) | MEMBRANE PROTEIN, LIGANDED-GATED ION CHANNEL, TRANSPORT PROTEIN
3uq4:G (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F247L (F16L) | MEMBRANE PROTEIN, LIGANDED-GATED ION CHANNEL, TRANSPORT PROTEIN
3uq4:H (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F247L (F16L) | MEMBRANE PROTEIN, LIGANDED-GATED ION CHANNEL, TRANSPORT PROTEIN
3uq4:I (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F247L (F16L) | MEMBRANE PROTEIN, LIGANDED-GATED ION CHANNEL, TRANSPORT PROTEIN
3uq4:J (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) MUTANT F247L (F16L) | MEMBRANE PROTEIN, LIGANDED-GATED ION CHANNEL, TRANSPORT PROTEIN
3uzb:A (SER297) to (TYR324) CRYSTAL STRUCTURES OF BRANCHED-CHAIN AMINOTRANSFERASE FROM DEINOCOCCUS RADIODURANS COMPLEXES WITH ALPHA-KETOISOCAPROATE AND L-GLUTAMATE SUGGEST ITS RADIO-RESISTANCE FOR CATALYSIS | BCAT, AMINO-ACID BIOSYNTHESIS, AMINOTRANSFERASE, BRANCHED-CHAIN AMINO ACID BIOSYNTHESIS, PYRIDOXAL PHOSPHATE, TRANSFERASE, ALPHA- KETOISOCAPROATE
3uzb:D (SER297) to (PHE323) CRYSTAL STRUCTURES OF BRANCHED-CHAIN AMINOTRANSFERASE FROM DEINOCOCCUS RADIODURANS COMPLEXES WITH ALPHA-KETOISOCAPROATE AND L-GLUTAMATE SUGGEST ITS RADIO-RESISTANCE FOR CATALYSIS | BCAT, AMINO-ACID BIOSYNTHESIS, AMINOTRANSFERASE, BRANCHED-CHAIN AMINO ACID BIOSYNTHESIS, PYRIDOXAL PHOSPHATE, TRANSFERASE, ALPHA- KETOISOCAPROATE
1gk9:B (VAL118) to (ALA142) CRYSTAL STRUCTURES OF PENICILLIN ACYLASE ENZYME-SUBSTRATE COMPLEXES: STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM | ANTIBIOTIC RESISTANCE, AMIDASE, NTN-HYDROLASE,
3hz3:A (ASN1648) to (ASP1675) LACTOBACILLUS REUTERI N-TERMINALLY TRUNCATED GLUCANSUCRASE GTF180(D1025N)-SUCROSE COMPLEX | PROTEIN-SUCROSE COMPLEX, MULTIDOMAIN PROTEIN, GLYCOSYLTRANSFERASE, TRANSFERASE
4ktc:A (GLY140) to (ILE170) NS3/NS4A PROTEASE WITH INHIBITOR | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ktc:C (GLY140) to (ILE170) NS3/NS4A PROTEASE WITH INHIBITOR | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1smx:B (GLY66) to (THR118) CRYSTAL STRUCTURE OF THE S1 DOMAIN OF RNASE E FROM E. COLI (NATIVE) | OB-FOLD, RNA-BINDING, HYDROLASE
1sqa:A (GLY213) to (TYR244) SUBSTITUTED 2-NAPHTHAMIDINE INHIBITORS OF UROKINASE | PLASMINOGEN ACTIVATION, HYDROLASE, SERINE PROTEASE, GLYCOPROTEIN, KRINGLE, EGF-LIKE DOMAIN
4zj6:A (VAL65) to (LYS107) THE CRYSTAL STRUCTURE OF HUMAN PLASMA KALLIKREIN IN COMPLEX WITH ITS PEPTIDE INHIBITOR PKALIN-3 | PEPTIDE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1h1b:A (SER197) to (ALA229) CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL ELASTASE COMPLEXED WITH AN INHIBITOR (GW475151) | HYDROLASE, SERINE PROTEASE,
1h1b:B (SER197) to (ALA229) CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL ELASTASE COMPLEXED WITH AN INHIBITOR (GW475151) | HYDROLASE, SERINE PROTEASE,
1t31:A (GLY197) to (THR229) A DUAL INHIBITOR OF THE LEUKOCYTE PROTEASES CATHEPSIN G AND CHYMASE WITH THERAPEUTIC EFFICACY IN ANIMALS MODELS OF INFLAMMATION | HUMAN CHYMASE, SERINE PROTEINASE, HYDROLASE
3ies:A (ARG337) to (GLY394) FIREFLY LUCIFERASE INHIBITOR COMPLEX | OXIDOREDUCTASE, MONOOXYGENASE, PHOTOPROTEIN, LUMINESCENCE, ATP-BINDING, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, PEROXISOME
1t8n:C (ALA179) to (GLY211) CRYSTAL STRUCTURE OF THE P1 THR BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX | CHYMOTRYPSIN, SERINE PROTEINASE, BOVINE PANCREATIC TRYPSIN INHIBITOR, BPTI, PROTEIN-PROTEIN INTERACTION, NON-COGNATE BINDING, S1 POCKET, PRIMARY SPECIFICITY, CRYSTAL STRUCTURE, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
4zro:D (ASN64) to (LYS89) 2.1 A X-RAY STRUCTURE OF FIPV-3CLPRO BOUND TO COVALENT INHIBITOR | CORONAVIRUS, MAIN PROTEASE, 3CLPRO, MPRO, FIPV, FCOV, INHIBITOR COMPLEX, FELINE INFECTIOUS PERITONITIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1hcx:A (LYS247) to (ASP272) CHOLINE BINDING DOMAIN OF THE MAJOR AUTOLYSIN (C-LYTA) FROM STREPTOCOCCUS PNEUMONIAE | CHOLINE-BINDING DOMAIN, CELL WALL ATTACHMENT
1hcx:B (GLY291) to (LYS318) CHOLINE BINDING DOMAIN OF THE MAJOR AUTOLYSIN (C-LYTA) FROM STREPTOCOCCUS PNEUMONIAE | CHOLINE-BINDING DOMAIN, CELL WALL ATTACHMENT
2w86:A (THR44) to (ASN61) CRYSTAL STRUCTURE OF FIBRILLIN-1 DOMAINS CBEGF9HYB2CBEGF10, CALCIUM SATURATED FORM | FIBRILLIN, PHOSPHOPROTEIN, EGF-LIKE DOMAIN, DISEASE MUTATION, CRANIOSYNOSTOSIS, EXTRACELLULAR MATRIX, FIBRILLIN CALCIUM CBEGF HYBRID, CALCIUM, SECRETED, POLYMORPHISM, GLYCOPROTEIN
2h23:A (LEU232) to (SER273) STRUCTURE OF RUBISCO LSMT BOUND TO TRIMETHYLLYSINE AND ADOHCY | SET DOMAIN, PROTEIN LYSINE METHYLTRANSFERASE, TRANSFERASE
3vml:A (LYS128) to (SER166) CHIMERA 3-ISOPROPYLMALATE DEHYDROGENASE BETWEEN SHEWANELLA ONEIDENSIS MR-1 (O) AND SHEWANELLA BENTHICA DB21 MT-2 (M) FROM N-TERMINAL: 20% O MIDDLE 70% M RESIDUAL 10% O | OXIDOREDUCTASE, DECARBOXYLATING DEHYDROGENASE
2hrv:A (GLY108) to (ILE131) 2A CYSTEINE PROTEINASE FROM HUMAN RHINOVIRUS 2 | HYDROLASE (CYSTEINE PROTEINASE)
2hrv:B (GLY108) to (ILE131) 2A CYSTEINE PROTEINASE FROM HUMAN RHINOVIRUS 2 | HYDROLASE (CYSTEINE PROTEINASE)
1id5:H (ARG206) to (THR229) CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEX WITH PROTEASE INHIBITOR ECOTIN | THROMBIN, ECOTIN M84R, CONFORMATIONAL CHANGES, HYDROLASE
2i47:D (LEU348) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TACE WITH INHIBITOR | TACE/ADAM-17, TACE-INHIBITOR COMPLEX, HYDROLASE
2i9u:A (ASN9) to (ASP31) CRYSTAL STRUCTURE OF GUANINE DEAMINASE FROM C. ACETOBUTYLICUM WITH BOUND GUANINE IN THE ACTIVE SITE | PROTEIN STRUCTURE INITIATIVE II (PSI-II), 9246A, AMIDOHYDROLASE, GUANINE DEAMINASE, NUCLEOTIDE TRANSPORT AND METABOLISM, STRUCTURAL GENOMICS, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, HYDROLASE
4mb5:A (VAL33) to (GLU55) CRYSTAL STRUCTURE OF E153Q MUTANT OF COLD-ADAPTED CHITINASE FROM MORITELLA COMPLEX WITH NAG5 | TIM-BARREL, ALPHA/BETA-BARREL IG-LIKE, IMMUNOGLOBULIN LIKE DOMAIN, CHBD, CHITIN BINDING DOMAIN, CHITINASE, HYDROLAZE, LOW ACTIVITY MUTANT, NAG5, HYDROLASE, LIGAND BINDING
1izd:A (SER62) to (ASP84) CRYSTAL STRUCTURE OF ASPERGILLUS ORYZAE ASPARTIC PROTEINASE | SUGAR BINDING, ACID PROTEASE, HYDROLASE
1j3b:B (GLY211) to (GLY232) CRYSTAL STRUCTURE OF ATP-DEPENDENT PHOSPHOENOLPYRUVATE CARBOXYKINASE FROM THERMUS THERMOPHILUS HB8 | PHOSPHOENOLPYRUVATE CARBOXYKINASE, ADENOSINE TRIPHOSPHATE, THERMUS THERMOPHILUS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
3wmc:A (GLY291) to (ASN335) CRYSTAL STRUCTURE OF INSECT BETA-N-ACETYL-D-HEXOSAMINIDASE OFHEX1 COMPLEXED WITH NAPHTHALIMIDE DERIVATIVE Q2 | CHITINASE, GLYCOSYL HYDROLASE, INSECT, OSTRINIA FURNACALIS, HYDROLASE
1vcq:B (GLY220) to (SER247) SEMLIKI FOREST VIRUS CAPSID PROTEIN (CRYSTAL FORM II) | VIRUS COAT PROTEIN, POLYPROTEIN, TRANSMEMBRANE, GLYCOPROTEIN, NUCLEOCAPSID PROTEIN, VIRAL PROTEIN
2xcf:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR | PROTEASE, BORONATE INHIBITOR, VIRAL REPRODUCTION, HYDROLASE
2xcf:B (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR | PROTEASE, BORONATE INHIBITOR, VIRAL REPRODUCTION, HYDROLASE
4mpx:A (THR235) to (THR258) HUMAN BETA-TRYPTASE CO-CRYSTAL STRUCTURE WITH [(1,1,3,3- TETRAMETHYLDISILOXANE-1,3-DIYL)DI-1-BENZOTHIENE-4,2-DIYL]BIS({4-[3- (AMINOMETHYL)PHENYL]PIPERIDIN-1-YL}METHANONE) | COFERON, ALPHA-HYDROXYKETONE, SMALL MOLECULE INHIBITOR, DRUG DISCOVERY, SELF-ASSEMBLY, CRYSTAL CATALYSIS, SILANOL, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3j9t:E (GLU47) to (GLN71) YEAST V-ATPASE STATE 1 | V-ATPASE, V-TYPE ATPASE, VACUOLAR-TYPE ATPASE, PROTON PUMP, HYDROLASE
3j9t:E (ASP150) to (LEU174) YEAST V-ATPASE STATE 1 | V-ATPASE, V-TYPE ATPASE, VACUOLAR-TYPE ATPASE, PROTON PUMP, HYDROLASE
1w3c:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS3 PROTEASE IN COMPLEX WITH A PEPTIDOMIMETIC INHIBITOR | HYDROLASE, SERINE PROTEASE, HCV, INDOLINE-BASED PEPTIDOMIMETIC INHIBITOR
1w3c:B (GLY140) to (ILE170) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS3 PROTEASE IN COMPLEX WITH A PEPTIDOMIMETIC INHIBITOR | HYDROLASE, SERINE PROTEASE, HCV, INDOLINE-BASED PEPTIDOMIMETIC INHIBITOR
1w4c:A (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:B (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:C (ASP55) to (VAL86) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:D (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:E (ASP55) to (VAL86) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:F (ASP55) to (VAL86) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:G (ASP55) to (VAL86) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:H (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:I (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:J (ASP55) to (VAL86) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:K (ASP55) to (VAL86) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:L (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:M (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:N (ASP55) to (VAL86) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:O (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:P (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:Q (ASP55) to (VAL86) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:R (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:S (ASP55) to (VAL86) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:T (ASP55) to (VAL86) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:U (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:V (ASP55) to (VAL86) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:W (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
1w4c:X (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 APO STATE | HYDROLASE, DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE HYDROLASE
4nc1:B (ASN224) to (GLY251) CRYSTAL STRUCTURE OF TCDA-A2 BOUND TO A20.1 VHH AND A26.8 VHH | ANTIBODY-ANTIGEN COMPLEX, IMMUNE SYSTEM
3jba:D (LEU42) to (GLY67) THE U4 ANTIBODY EPITOPE ON HUMAN PAPILLOMAVIRUS 16 IDENTIFIED BY CRYO- EM | HPV16, ANTIBODY, U4, NEUTRALIZATION, FAB, VIRUS-IMMUNE SYSTEM COMPLEX
3jba:C (LEU42) to (GLY67) THE U4 ANTIBODY EPITOPE ON HUMAN PAPILLOMAVIRUS 16 IDENTIFIED BY CRYO- EM | HPV16, ANTIBODY, U4, NEUTRALIZATION, FAB, VIRUS-IMMUNE SYSTEM COMPLEX
5c1c:A (SER262) to (ASN288) CRYSTAL STRUCTURE OF THE PECTIN METHYLESTERASE FROM ASPERGILLUS NIGER IN DEGLYCOSYLATED FORM | PARALLEL BETA HELIX, PECTIN METHYLESTERASE, HYDROLASE
2m5t:A (GLY107) to (THR130) SOLUTION STRUCTURE OF THE 2A PROTEINASE FROM A COMMON COLD AGENT, HUMAN RHINOVIRUS RV-C02, STRAIN W12 | HUMAN RHINOVIRUS C, 2A PROTEINASE, CYSTEINE PROTEINASE, VIRAL PROTEIN
4nsv:A (SER196) to (GLY228) LYSOBACTER ENZYMOGENES LYSC ENDOPROTEINASE K30R MUTANT COVALENTLY INHIBITED BY TLCK | HYDROLASE, ENDOPROTEINASE, AROMATIC STACK, ATOMIC RESOLUTION, SERINE PROTEASE, CATALYTIC TRIAD, COVALENT INHIBITION, TLCK;, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4nsv:B (SER196) to (GLY228) LYSOBACTER ENZYMOGENES LYSC ENDOPROTEINASE K30R MUTANT COVALENTLY INHIBITED BY TLCK | HYDROLASE, ENDOPROTEINASE, AROMATIC STACK, ATOMIC RESOLUTION, SERINE PROTEASE, CATALYTIC TRIAD, COVALENT INHIBITION, TLCK;, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4nwk:A (GLY140) to (ILE170) CRYSTAL STRUCTURE OF HEPATIS C VIRUS PROTEASE (NS3) COMPLEXED WITH BMS-605339 AKA N-(TERT-BUTOXYCARBONYL)-3-ME THYL-L-VALYL-(4R)-N-((1R, 2S)-1-((CYCLOPROPYLSULFONYL)CARBA MOYL)-2-VINYLCYCLOPROPYL)-4-((6- METHOXY-1-ISOQUINOLINYL)OX Y)-L-PROLINAMIDE | HYDROLASE/HYDROLASE INHIBITOR, SERINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2yoe:D (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH GABA AND FLURAZEPAM | TRANSPORT PROTEIN, CYS-LOOP RECEPTOR, GABA-A RECEPTOR, BENZODIAZEPINE
2yoe:F (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH GABA AND FLURAZEPAM | TRANSPORT PROTEIN, CYS-LOOP RECEPTOR, GABA-A RECEPTOR, BENZODIAZEPINE
1lci:A (ILE336) to (GLY394) FIREFLY LUCIFERASE | OXIDOREDUCTASE, MONOOXYGENASE, PHOTOPROTEIN, LUMINESCENCE
4om9:A (SER210) to (THR243) X-RAY CRYSTAL STRUCTURE OF THE PASSENGER DOMAIN OF PLASMID ENCODED TOXIN, AN AUTROTANSPORTER ENTEROTOXIN FROM ENTEROAGGREGATIVE ESCHERICHIA COLI (EAEC) | BETA-HELIX, PEPTIDASE, ALPHA-FODRIN, HYDROLASE, EAEC, PLASMID ENCODED TOXIN(PET)
4a92:A (GLY140) to (VAL170) FULL-LENGTH HCV NS3-4A PROTEASE-HELICASE IN COMPLEX WITH A MACROCYCLIC PROTEASE INHIBITOR. | HYDROLASE, DRUG DESIGN
4a92:B (GLY140) to (VAL170) FULL-LENGTH HCV NS3-4A PROTEASE-HELICASE IN COMPLEX WITH A MACROCYCLIC PROTEASE INHIBITOR. | HYDROLASE, DRUG DESIGN
3khx:A (ASN76) to (ARG111) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS METALLOPEPTIDASE (SAPEP/DAPE) IN THE APO-FORM | DIPEPTIDASE, DAPE, METALLOPEPTIDASE, HYDROLASE, METAL-BINDING, METALLOPROTEASE, PROTEASE
4acu:A (THR59) to (ASP83) AMINOIMIDAZOLES AS BACE-1 INHIBITORS. X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 14 | HYDROLASE, ALZHEIMER'S DISEASE
4p0r:C (THR297) to (ASP329) HUMAN MUS81-EME1-3'FLAP DNA COMPLEX | RESOLVASE, HYDROLASE-DNA COMPLEX
4afz:A (GLY184) to (THR210) HUMAN CHYMASE - FYNOMER COMPLEX | HYDROLASE-DE NOVO PROTEIN COMPLEX, INHIBITOR, SERINE PROTEASE
4afz:B (GLY184) to (THR210) HUMAN CHYMASE - FYNOMER COMPLEX | HYDROLASE-DE NOVO PROTEIN COMPLEX, INHIBITOR, SERINE PROTEASE
1mkw:H (ARG206) to (THR229) THE CO-CRYSTAL STRUCTURE OF UNLIGANDED BOVINE ALPHA- THROMBIN AND PRETHROMBIN-2: MOVEMENT OF THE YPPW SEGMENT AND ACTIVE SITE RESIDUES UPON LIGAND BINDING | COMPLEX (BLOOD COAGULATION/PROENZYME), THROMBIN, PRETHROMBIN-2, PLASMA, SERINE PROTEASE
3kme:A (GLY349) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TACE WITH PHENYL- PYRROLIDINYL-TARTRATE INHIBITOR | A DISINTEGRIN AND METALLOPROTEINASE DOMAIN 17, TNF-ALPHA-CONVERTING ENZYME, TNF-ALPHA CONVERTASE, SNAKE VENOM-LIKE PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, GLYCOPROTEIN, MEMBRANE, METAL-BINDING, METALLOPROTEASE, NOTCH SIGNALING PATHWAY, PHOSPHOPROTEIN, PROTEASE, ZYMOGEN, HYDROLASE
3kme:B (LEU348) to (ASN381) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF TACE WITH PHENYL- PYRROLIDINYL-TARTRATE INHIBITOR | A DISINTEGRIN AND METALLOPROTEINASE DOMAIN 17, TNF-ALPHA-CONVERTING ENZYME, TNF-ALPHA CONVERTASE, SNAKE VENOM-LIKE PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, GLYCOPROTEIN, MEMBRANE, METAL-BINDING, METALLOPROTEASE, NOTCH SIGNALING PATHWAY, PHOSPHOPROTEIN, PROTEASE, ZYMOGEN, HYDROLASE
1y8t:C (GLY170) to (ILE208) CRYSTAL STRUCTURE OF RV0983 FROM MYCOBACTERIUM TUBERCULOSIS- PROTEOLYTICALLY ACTIVE FORM | SERINE PROTEASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, UNKNOWN FUNCTION
3a5d:A (GLY164) to (MET183) INTER-SUBUNIT INTERACTION AND QUATERNARY REARRANGEMENT DEFINED BY THE CENTRAL STALK OF PROKARYOTIC V1-ATPASE | V-ATPASE, ASYMMETRIC, CRYSTAL STRUCTURE, ROTATION, VACUOLAR TYPE, HYDROLASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
3a5d:B (GLY164) to (MET183) INTER-SUBUNIT INTERACTION AND QUATERNARY REARRANGEMENT DEFINED BY THE CENTRAL STALK OF PROKARYOTIC V1-ATPASE | V-ATPASE, ASYMMETRIC, CRYSTAL STRUCTURE, ROTATION, VACUOLAR TYPE, HYDROLASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
3a5d:C (GLY164) to (MET183) INTER-SUBUNIT INTERACTION AND QUATERNARY REARRANGEMENT DEFINED BY THE CENTRAL STALK OF PROKARYOTIC V1-ATPASE | V-ATPASE, ASYMMETRIC, CRYSTAL STRUCTURE, ROTATION, VACUOLAR TYPE, HYDROLASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
3a5d:I (GLY164) to (MET183) INTER-SUBUNIT INTERACTION AND QUATERNARY REARRANGEMENT DEFINED BY THE CENTRAL STALK OF PROKARYOTIC V1-ATPASE | V-ATPASE, ASYMMETRIC, CRYSTAL STRUCTURE, ROTATION, VACUOLAR TYPE, HYDROLASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
3a5d:J (GLY164) to (MET183) INTER-SUBUNIT INTERACTION AND QUATERNARY REARRANGEMENT DEFINED BY THE CENTRAL STALK OF PROKARYOTIC V1-ATPASE | V-ATPASE, ASYMMETRIC, CRYSTAL STRUCTURE, ROTATION, VACUOLAR TYPE, HYDROLASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
3a5d:K (GLY164) to (MET183) INTER-SUBUNIT INTERACTION AND QUATERNARY REARRANGEMENT DEFINED BY THE CENTRAL STALK OF PROKARYOTIC V1-ATPASE | V-ATPASE, ASYMMETRIC, CRYSTAL STRUCTURE, ROTATION, VACUOLAR TYPE, HYDROLASE, ATP SYNTHESIS, ATP-BINDING, HYDROGEN ION TRANSPORT, ION TRANSPORT, NUCLEOTIDE-BINDING, TRANSPORT
1yjl:A (VAL154) to (ARG195) REDUCED PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE IN A NEW CRYSTAL FORM | MONOOXYGENASE, BIOACTIVE PEPTIDE ACTIVATION, COPPER, ASCORBATE, OXIDOREDUCTASE
1ykj:A (ASP1068) to (ASP1087) A45G P-HYDROXYBENZOATE HYDROXYLASE WITH P-HYDROXYBENZOATE BOUND | PHBH, CATALYSIS, CONFORMATIONS, OXIDOREDUCTASE
3ak5:A (HIS507) to (ASP531) HEMOGLOBIN PROTEASE (HBP) PASSENGER MISSING DOMAIN-2 | AUTOTRANSPORTER, BETA HELIX, MUTANT, HYDROLASE
3ak5:B (HIS507) to (ASP531) HEMOGLOBIN PROTEASE (HBP) PASSENGER MISSING DOMAIN-2 | AUTOTRANSPORTER, BETA HELIX, MUTANT, HYDROLASE
1zm4:C (PRO559) to (PRO592) STRUCTURE OF THE EEF2-ETA-BTAD COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
1zm4:E (ALA562) to (PRO592) STRUCTURE OF THE EEF2-ETA-BTAD COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
2a4g:C (GLY140) to (ILE170) HEPATITIS C PROTEASE NS3-4A SERINE PROTEASE WITH KETOAMIDE INHIBITOR SCH225724 BOUND | VIRAL PROTEIN
2a4q:A (GLY140) to (ILE170) HCV NS3 PROTEASE WITH NS4A PEPTIDE AND A COVALENTLY BOUND MACROCYCLIC KETOAMIDE COMPOUND. | VIRAL PROTEIN
2a4q:C (GLY140) to (ILE170) HCV NS3 PROTEASE WITH NS4A PEPTIDE AND A COVALENTLY BOUND MACROCYCLIC KETOAMIDE COMPOUND. | VIRAL PROTEIN
4b6e:A (GLY140) to (VAL170) DISCOVERY OF AN ALLOSTERIC MECHANISM FOR THE REGULATION OF HCV NS3 PROTEIN FUNCTION | HYDROLASE, HELICASE-PROTEASE, ALLOSTERIC POCKET, FUSION PROTEIN
4b6f:A (GLY140) to (VAL170) DISCOVERY OF AN ALLOSTERIC MECHANISM FOR THE REGULATION OF HCV NS3 PROTEIN FUNCTION | HYDROLASE, HELICASE-PROTEASE, ALLOSTERIC POCKET, FUSION PROTEIN
4b6f:B (GLY140) to (VAL170) DISCOVERY OF AN ALLOSTERIC MECHANISM FOR THE REGULATION OF HCV NS3 PROTEIN FUNCTION | HYDROLASE, HELICASE-PROTEASE, ALLOSTERIC POCKET, FUSION PROTEIN
3m5o:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH N-TERMINAL PRODUCT 5A5B | HCV, HEPATITIS C VIRUS, NS3, PROTEASE, DRUG RESISTANCE, SERINE PROTEASE, CHIMERA PROTEIN, FUSION PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3m5o:B (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH N-TERMINAL PRODUCT 5A5B | HCV, HEPATITIS C VIRUS, NS3, PROTEASE, DRUG RESISTANCE, SERINE PROTEASE, CHIMERA PROTEIN, FUSION PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3mi2:A (LEU224) to (SER245) CRYSTAL STRUCTURE OF HUMAN OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH PYRAZOFURIN MONOPHOSPHATE | UMP SYNTHASE, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, PYRAZOFURIN MONOPHOSPHATE, LYASE
3mi2:B (LEU224) to (SER245) CRYSTAL STRUCTURE OF HUMAN OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH PYRAZOFURIN MONOPHOSPHATE | UMP SYNTHASE, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, PYRAZOFURIN MONOPHOSPHATE, LYASE
5epy:A (GLY1140) to (ILE1170) CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE A156T VARIANT IN COMPLEX WITH 5172-MCP1P3 (MK-5172 P1-P3 MACROCYCLIC ANALOGUE) | GRAZOPREVIR ANALOGUE, MACROCYCLE, DRUG RESISTANCE, HCV PROTEASE INHIBITOR, MK-5172, HYDROLASE
3mlv:N (THR107) to (PRO147) CRYSTAL STRUCTURE OF ANTI-HIV-1 V3 FAB 2557 IN COMPLEX WITH AN NOF V3 PEPTIDE | HUMAN MONOCLONAL ANTIBODY, FAB, HIV-1, GP120, THIRD VARIABLE LOOP, ANTIBODY-ANTIGEN INTERACTION, IMMUNE SYSTEM
3bg4:C (ALA179) to (GLY211) THE CRYSTAL STRUCTURE OF GUAMERIN IN COMPLEX WITH CHYMOTRYPSIN AND THE DEVELOPMENT OF AN ELASTASE-SPECIFIC INHIBITOR | GUAMERIN, CHYMOTRYPSIN, ELASTASE, INHIBITOR, DIGESTION, HYDROLASE, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, PROTEASE INHIBITOR, SERINE PROTEASE INHIBITOR, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
4blr:A (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH UTP | HYDROLASE, PACKAGING, CYSTOVIRIDAE
4blr:B (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH UTP | HYDROLASE, PACKAGING, CYSTOVIRIDAE
4blr:C (ASP55) to (ASN88) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH UTP | HYDROLASE, PACKAGING, CYSTOVIRIDAE
4rrs:A (THR120) to (GLU140) 8-TETRAHYDROPYRAN-2-YL CHROMANS: HIGHLY SELECTIVE BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1 (BACE1) INHIBITORS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4s0n:A (ASP56) to (ASN102) CRYSTAL STRUCTURE OF HLTF HIRAN DOMAIN BOUND TO DNA | ALPHA+BETA, DNA 3'-END BINDING, DNA BINDING PROTEIN-DNA COMPLEX
4s0n:B (ASP56) to (ASN102) CRYSTAL STRUCTURE OF HLTF HIRAN DOMAIN BOUND TO DNA | ALPHA+BETA, DNA 3'-END BINDING, DNA BINDING PROTEIN-DNA COMPLEX
4s0n:C (ASP56) to (ASN102) CRYSTAL STRUCTURE OF HLTF HIRAN DOMAIN BOUND TO DNA | ALPHA+BETA, DNA 3'-END BINDING, DNA BINDING PROTEIN-DNA COMPLEX
4s0n:D (ASP56) to (ASN102) CRYSTAL STRUCTURE OF HLTF HIRAN DOMAIN BOUND TO DNA | ALPHA+BETA, DNA 3'-END BINDING, DNA BINDING PROTEIN-DNA COMPLEX
3dbp:A (LEU224) to (SER245) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 6-NH2-UMP | HUMAN, UMP SYNTHASE, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, 6-NH2-UMP, ALTERNATIVE SPLICING, DECARBOXYLASE, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, POLYMORPHISM, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
5gw5:a (TYR354) to (GLY376) STRUCTURE OF TRIC-AMP-PNP | CHAPERONIN, YEAST, CHAPERONE
3otp:A (VAL112) to (GLN140) CRYSTAL STRUCTURE OF THE DEGP DODECAMER WITH A MODEL SUBSTRATE | TYPSIN-LIKE PROTEASE DOMAIN PDZ DOMAINS, PROTEASE, HYDROLASE
3otp:B (GLY211) to (ILE242) CRYSTAL STRUCTURE OF THE DEGP DODECAMER WITH A MODEL SUBSTRATE | TYPSIN-LIKE PROTEASE DOMAIN PDZ DOMAINS, PROTEASE, HYDROLASE
3otp:C (VAL112) to (GLN140) CRYSTAL STRUCTURE OF THE DEGP DODECAMER WITH A MODEL SUBSTRATE | TYPSIN-LIKE PROTEASE DOMAIN PDZ DOMAINS, PROTEASE, HYDROLASE
3otp:D (VAL112) to (GLN140) CRYSTAL STRUCTURE OF THE DEGP DODECAMER WITH A MODEL SUBSTRATE | TYPSIN-LIKE PROTEASE DOMAIN PDZ DOMAINS, PROTEASE, HYDROLASE
3otp:E (VAL112) to (GLN140) CRYSTAL STRUCTURE OF THE DEGP DODECAMER WITH A MODEL SUBSTRATE | TYPSIN-LIKE PROTEASE DOMAIN PDZ DOMAINS, PROTEASE, HYDROLASE
3owe:F (VAL35) to (GLU68) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN G (SEG) IN COMPLEX WITH A HIGH AFFINITY MUTANT MOUSE T-CELL RECEPTOR CHAIN | T-CELL RECEPTOR V BETA DOMAIN, COMPLEX STRUCTURE, IGG DOMAINS, B GRASP, VIRULENCE FACTORS, IMMUNE SYSTEM
3owe:H (PRO34) to (GLU68) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN G (SEG) IN COMPLEX WITH A HIGH AFFINITY MUTANT MOUSE T-CELL RECEPTOR CHAIN | T-CELL RECEPTOR V BETA DOMAIN, COMPLEX STRUCTURE, IGG DOMAINS, B GRASP, VIRULENCE FACTORS, IMMUNE SYSTEM
3owe:J (PRO34) to (GLU68) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN G (SEG) IN COMPLEX WITH A HIGH AFFINITY MUTANT MOUSE T-CELL RECEPTOR CHAIN | T-CELL RECEPTOR V BETA DOMAIN, COMPLEX STRUCTURE, IGG DOMAINS, B GRASP, VIRULENCE FACTORS, IMMUNE SYSTEM
4dku:A (GLY263) to (ASN289) CRYSTAL STRUCTURE OF CLADE A/E 93TH057 HIV-1 GP120 CORE IN COMPLEX WITH NBD-09027 | HIV-1 GP120, CLADE A/E, CD4 MIMIC, NBD-09027, HYDROLASE
3pcf:F (GLY119) to (ARG142) STRUCTURE OF PROTOCATECHUATE 3,4-DIOXYGENASE COMPLEXED WITH 3-FLURO-4- HYDROXYBENZOATE | DIOXYGENASE, IRON, NONHEME, METALLOPROTEIN, OXIDOREDUCTASE, INHIBITOR COMPLEX
3pky:A (PRO61) to (ASP94) POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D IN COMPLEX WITH DNA, UTP AND MANGANESE. | PROTEIN-DNA COMPLEX, TRANSFERASE-DNA COMPLEX, NUCLEOTIDE-BINDING, POLYMERASE, PRIMASE, TRANSFERASE, NHEJ
3pky:B (PRO61) to (ASP94) POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D IN COMPLEX WITH DNA, UTP AND MANGANESE. | PROTEIN-DNA COMPLEX, TRANSFERASE-DNA COMPLEX, NUCLEOTIDE-BINDING, POLYMERASE, PRIMASE, TRANSFERASE, NHEJ
5ife:A (VAL773) to (HIS804) CRYSTAL STRUCTURE OF THE HUMAN SF3B CORE COMPLEX | PRE-MRNA SPLICING, U2 SNRNP, ESSENTIAL SPLICING FACTOR, SPLICING
4vgc:C (ALA179) to (GLY211) GAMMA-CHYMOTRYPSIN D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX | HYDROLASE, SERINE PROTEASE
4fig:A (GLY435) to (LEU456) CATALYTIC DOMAIN OF HUMAN PAK4 | SERINE/THREONINE-PROTEIN KINASE PAK4, KINASE DOMAIN, PROTEIN KINASE, ATP BINDING, PHOSPHORYLATION, TRANSFERASE
4fig:B (GLY435) to (LEU456) CATALYTIC DOMAIN OF HUMAN PAK4 | SERINE/THREONINE-PROTEIN KINASE PAK4, KINASE DOMAIN, PROTEIN KINASE, ATP BINDING, PHOSPHORYLATION, TRANSFERASE
3r11:A (ASP7) to (ASN29) CRYSTAL STRUCTURE OF NYSGRC ENOLASE TARGET 200555, A PUTATIVE DIPEPTIDE EPIMERASE FROM FRANCISELLA PHILOMIRAGIA : MG AND FUMARATE COMPLEX | ENOLASE, STRUCTURAL GENOMICS, PUTATIVE EPIMERASE, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, ISOMERASE
5knd:C (ASP26) to (GLN50) CRYSTAL STRUCTURE OF THE PI-BOUND V1 COMPLEX | P-LOOP, HYDROLASE, NA(+)-ATPASE, ATP BINDING
4gpg:A (SER196) to (GLY228) X/N JOINT REFINEMENT OF ACHROMOBACTER LYTICUS PROTEASE I FREE FORM AT PD8.0 | LYSINE SPECIFIC SERINE PROTEASE, HYDROLASE
5kzc:C (GLY66) to (ALA92) CRYSTAL STRUCTURE OF AN HIV-1 GP120 ENGINEERED OUTER DOMAIN WITH A MAN9 GLYCAN AT POSITION N276, IN COMPLEX WITH BROADLY NEUTRALIZING ANTIBODY VRC01 | HIV, ENV, GP120, NEUTRALIZING ANTIBODY, N-LINKED GLYCAN, IMMUNE SYSTEM
5lc0:A (GLY1136) to (ILE1165) CRYSTAL STRUCTURE OF ZIKA VIRUS NS2B-NS3 PROTEASE IN COMPLEX WITH A BORONATE INHIBITOR | ZIKA VIRUS NS2B-NS3 PROTEASE, ANTIVIRAL AGENTS, BORONIC-ACID INHIBITOR, CYCLIC DIESTER WITH GLYCEROL, HYDROLASE
5lid:D (GLU159) to (PRO201) X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH BROMOPROMAZINE | LIGAND-GATED ION CHANNEL, TRANSPORT PROTEIN
5ljz:A (GLY187) to (HIS213) STRUCTURE OF HANTAVIRUS ENVELOPE GLYCOPROTEIN GC IN POSTFUSION CONFORMATION | HANTAVIRUS, GLYCOPROTEIN, VIRAL FUSION, VIRAL PROTEIN
5lk1:A (GLY187) to (PHE211) STRUCTURE OF HANTAVIRUS ENVELOPE GLYCOPROTEIN GC IN POSTFUSION CONFORMATION IN PRESENCE OF 200 MM KCL | HANTAVIRUS, GLYCOPROTEIN, VIRAL FUSION, VIRAL PROTEIN