4grs:C (ASP80) to (GLY100) CRYSTAL STRUCTURE OF A CHIMERIC DAH7PS | DAHP, DAHPS, DAH7PS, TIM BARREL, ACT DOMAIN, TRANSFERASE, ALLOSTERIC REGULATION, AROMATIC BIOSYNTHESIS, SHIKIMATE PATHWAY, TRANSFERABLE ALLOSTERY
3e6i:A (ASP375) to (THR392) HUMAN CYTOCHROME P450 2E1 IN COMPLEX WITH THE INHIBITOR INDAZOLE | CYP2E1, P450 2E1, MONOOXYGENASE, ACETAMINOPHEN, OXIDOREDUCTASE, HEME, ENDOPLASMIC RETICULUM, IRON, MEMBRANE, METAL-BINDING, MICROSOME
3e6i:B (ASP375) to (THR392) HUMAN CYTOCHROME P450 2E1 IN COMPLEX WITH THE INHIBITOR INDAZOLE | CYP2E1, P450 2E1, MONOOXYGENASE, ACETAMINOPHEN, OXIDOREDUCTASE, HEME, ENDOPLASMIC RETICULUM, IRON, MEMBRANE, METAL-BINDING, MICROSOME
2oah:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE COMPLEXED WITH INHIBITOR | ASPARTYL PROTEASE, BACE, HYDROLASE
4wci:A (GLY36) to (LYS58) CRYSTAL STRUCTURE OF THE 1ST SH3 DOMAIN FROM HUMAN CD2AP (CMS) IN COMPLEX WITH A PROLINE-RICH PEPTIDE (AA 378-393) FROM HUMAN RIN3 | ENDOCYTOSIS ADAPTOR PROTEIN PROTEIN-PEPTIDE BINARY COMPLEX KIDNEY, SIGNALING PROTEIN, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
4wci:C (GLY36) to (LYS58) CRYSTAL STRUCTURE OF THE 1ST SH3 DOMAIN FROM HUMAN CD2AP (CMS) IN COMPLEX WITH A PROLINE-RICH PEPTIDE (AA 378-393) FROM HUMAN RIN3 | ENDOCYTOSIS ADAPTOR PROTEIN PROTEIN-PEPTIDE BINARY COMPLEX KIDNEY, SIGNALING PROTEIN, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
4wci:E (GLY36) to (LYS58) CRYSTAL STRUCTURE OF THE 1ST SH3 DOMAIN FROM HUMAN CD2AP (CMS) IN COMPLEX WITH A PROLINE-RICH PEPTIDE (AA 378-393) FROM HUMAN RIN3 | ENDOCYTOSIS ADAPTOR PROTEIN PROTEIN-PEPTIDE BINARY COMPLEX KIDNEY, SIGNALING PROTEIN, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
4gui:A (LYS2) to (THR26) 1.78 ANGSTROM CRYSTAL STRUCTURE OF THE SALMONELLA ENTERICA 3- DEHYDROQUINATE DEHYDRATASE (AROD) IN COMPLEX WITH QUINATE | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, TIM BARREL, LYASE
1a5d:A (SER85) to (HIS111) GAMMAE CRYSTALLIN FROM RAT LENS | EYE LENS PROTEIN
1a5d:B (SER85) to (HIS111) GAMMAE CRYSTALLIN FROM RAT LENS | EYE LENS PROTEIN
4wfs:A (VAL63) to (GLY89) CRYSTAL STRUCTURE OF TRNA-DIHYDROURIDINE(20) SYNTHASE CATALYTIC DOMAIN | RNA BINDING PROTEIN, TRNA PROCESSING, FLAVOPROTEIN, OXIDOREDUCTASE
4gv7:B (VAL948) to (PHE1009) HUMAN ARTD1 (PARP1) - CATALYTIC DOMAIN IN COMPLEX WITH INHIBITOR ME0328 | NAD, ADP-RIBOSE, PARP1, ARTD1, ARTD TRANSFERASE DOMAIN, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, ADP-RIBOSE TRANSFERASE
3rou:B (GLY45) to (GLY71) DOMAIN-DOMAIN FLEXIBILITY LEADS TO ALLOSTERY WITHIN THE CAMP RECEPTOR PROTEIN (CRP) | CAMP RECEPTOR PROTEIN (CRP), ALLOSTERY, DNA BINDING CYCLIC AMP, TRANSCRIPTION REGULATOR, CATABOLITE ACTIVATOR PROTEIN (CAP), DNA BINDING PROTEIN
2ohm:A (TYR342) to (PRO373) X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH N~3~-BENZYLPYRIDINE-2,3-DIAMINE | ALTERNATIVE SPLICING, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, SIGNAL, TRANSMEMBRANE, ZYMOGEN
2ohu:A (TYR342) to (PRO373) X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 8B | ALTERNATIVE SPLICING, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, SIGNAL, TRANSMEMBRANE, ZYMOGEN
4gy7:A (ASP704) to (ASP733) CRYSTALLOGRAPHIC STRUCTURE ANALYSIS OF UREASE FROM JACK BEAN (CANAVALIA ENSIFORMIS) AT 1.49 A RESOLUTION | PLANT UREASE, JACK BEAN, CANAVALIA ENSIFORMIS, HYDROLASE, METAL- BINDING, NICKEL
3ecq:A (ARG946) to (TRP969) ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE FROM STREPTOCOCCUS PNEUMONIAE: SEMET STRUCTURE | DISTORTED (BETA/ALPHA)8 (TIM) BARREL GLYCOSIDE HYDROLASE DOMAIN, CELL WALL, PEPTIDOGLYCAN-ANCHOR, SECRETED, HYDROLASE
3ecq:B (ARG946) to (TRP969) ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE FROM STREPTOCOCCUS PNEUMONIAE: SEMET STRUCTURE | DISTORTED (BETA/ALPHA)8 (TIM) BARREL GLYCOSIDE HYDROLASE DOMAIN, CELL WALL, PEPTIDOGLYCAN-ANCHOR, SECRETED, HYDROLASE
3efr:A (GLY210) to (ARG232) BIOTIN PROTEIN LIGASE R40G MUTANT FROM AQUIFEX AEOLICUS IN COMPLEX WITH BIOTIN | PROTEIN BIOTIN COMPLEX, LIGASE
3efr:B (GLY210) to (ARG232) BIOTIN PROTEIN LIGASE R40G MUTANT FROM AQUIFEX AEOLICUS IN COMPLEX WITH BIOTIN | PROTEIN BIOTIN COMPLEX, LIGASE
3efs:A (GLY210) to (ARG232) BIOTIN PROTEIN LIGASE FROM AQUIFEX AEOLICUS IN COMPLEX WITH BIOTIN AND ATP | BPL ATP BIOTIN COMPLEX, LIGASE
3efs:B (ALA212) to (ARG232) BIOTIN PROTEIN LIGASE FROM AQUIFEX AEOLICUS IN COMPLEX WITH BIOTIN AND ATP | BPL ATP BIOTIN COMPLEX, LIGASE
3rth:A (TYR342) to (PRO373) STRUCTURE OF BACE-1 (BETA-SECRETASE) IN COMPLEX WITH 6-(2-(3,3- DIMETHYLBUT-1-YNYL)PHENYL)QUINOLIN-2-AMINE | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3rtn:A (TYR342) to (PRO373) STRUCTURE OF BACE-1 (BETA-SECRETASE) IN COMPLEX WITH 3-(2-AMINO-6-O- TOLYLQUINOLIN-3-YL)-N-CYCLOHEXYLPROPANAMIDE | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2axt:B (VAL368) to (TYR390) CRYSTAL STRUCTURE OF PHOTOSYSTEM II FROM THERMOSYNECHOCOCCUS ELONGATUS | PHOTOSYSTEM, PS II, PS2, MEMBRANE COMPLEX, TRANSMEMBRANE ALPHA-HELIX, ELECTRON TRANSPORT
3ehw:A (ARG27) to (TYR54) HUMAN DUTPASE IN COMPLEX WITH ALPHA,BETA-IMIDO-DUTP AND MG2+: VISUALIZATION OF THE FULL-LENGTH C-TERMINI IN ALL MONOMERS AND SUGGESTION FOR AN ADDITIONAL METAL ION BINDING SITE | JELLY-ROLL, FULL-LENGTH C-TERMINAL ARM, ENZYME-LIGAND COMPLEX, HYDROLASE
3rvi:A (TYR342) to (PRO373) STRUCTURE OF BACE-1 (BETA-SECRETASE) IN COMPLEX WITH 2-((2-AMINO-6-O- TOLYLQUINOLIN-3-YL)METHYL)-N-(CYCLOHEXYLMETHYL)PENTANAMIDE | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4wnv:A (ILE382) to (LEU399) HUMAN CYTOCHROME P450 2D6 QUININE COMPLEX | CYP2D6, P450 2D6, P450, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4wnv:C (ILE382) to (LEU399) HUMAN CYTOCHROME P450 2D6 QUININE COMPLEX | CYP2D6, P450 2D6, P450, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4h1e:A (TYR403) to (PRO434) STRUCTURE OF BACE-1 BOUND TO (7AR)-6-BENZOYL-7A-(4-(3-CYANOPHENYL) THIOPHEN-2-YL)-3-METHYL-4-OXOHEXAHYDRO-1H-PYRROLO[3,4-D]PYRIMIDIN- 2(3H)-IMINIUM | HYDROLASE/HYDROLASE INHIBITOR, BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4h1e:B (TYR403) to (PRO434) STRUCTURE OF BACE-1 BOUND TO (7AR)-6-BENZOYL-7A-(4-(3-CYANOPHENYL) THIOPHEN-2-YL)-3-METHYL-4-OXOHEXAHYDRO-1H-PYRROLO[3,4-D]PYRIMIDIN- 2(3H)-IMINIUM | HYDROLASE/HYDROLASE INHIBITOR, BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ei4:A (LYS74) to (ILE100) STRUCTURE OF THE HSDDB1-HSDDB2 COMPLEX | UV-DAMAGE; DDB, NUCLEOTIDE EXCISION REPAIR, XERODERMA PIGMENTOSUM, DISEASE MUTATION, DNA DAMAGE, DNA REPAIR, DNA-BINDING, NUCLEUS, PHOSPHOPROTEIN, WD REPEAT, DNA BINDING PROTEIN
3ei4:C (LYS74) to (ILE100) STRUCTURE OF THE HSDDB1-HSDDB2 COMPLEX | UV-DAMAGE; DDB, NUCLEOTIDE EXCISION REPAIR, XERODERMA PIGMENTOSUM, DISEASE MUTATION, DNA DAMAGE, DNA REPAIR, DNA-BINDING, NUCLEUS, PHOSPHOPROTEIN, WD REPEAT, DNA BINDING PROTEIN
3ei4:E (LYS74) to (ILE100) STRUCTURE OF THE HSDDB1-HSDDB2 COMPLEX | UV-DAMAGE; DDB, NUCLEOTIDE EXCISION REPAIR, XERODERMA PIGMENTOSUM, DISEASE MUTATION, DNA DAMAGE, DNA REPAIR, DNA-BINDING, NUCLEUS, PHOSPHOPROTEIN, WD REPEAT, DNA BINDING PROTEIN
3ryb:A (TYR535) to (SER572) LACTOCOCCAL OPPA COMPLEXED WITH SLSQSLSQS | SUBSTRATE-BINDING PROTEIN, PEPTIDE BINDING, MEMBRANE ANCHORED, PEPTIDE BINDING PROTEIN
4h3d:A (LYS2) to (LYS26) 1.95 ANGSTROM CRYSTAL STRUCTURE OF OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE (AROD) FROM CLOSTRIDIUM DIFFICILE WITH COVALENT MODIFIED COMENIC ACID. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, TIM BARREL, ALDOLASE CLASS I, 3-DEHYDROQUINATE DEHYDRATASE ACTIVITY, LYASE
4h3d:B (LYS2) to (LYS26) 1.95 ANGSTROM CRYSTAL STRUCTURE OF OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE (AROD) FROM CLOSTRIDIUM DIFFICILE WITH COVALENT MODIFIED COMENIC ACID. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, TIM BARREL, ALDOLASE CLASS I, 3-DEHYDROQUINATE DEHYDRATASE ACTIVITY, LYASE
4h3d:C (LYS2) to (LYS26) 1.95 ANGSTROM CRYSTAL STRUCTURE OF OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE (AROD) FROM CLOSTRIDIUM DIFFICILE WITH COVALENT MODIFIED COMENIC ACID. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, TIM BARREL, ALDOLASE CLASS I, 3-DEHYDROQUINATE DEHYDRATASE ACTIVITY, LYASE
4h3f:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 3-(5-((7AR)-2-IMINO-6-(6-METHOXYPYRIDIN-2- YL)-3-METHYL-4-OXOOCTAHYDRO-1H-PYRROLO[3,4-D]PYRIMIDIN-7A-YL) THIOPHEN-3-YL)BENZONITRILE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4h3f:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 3-(5-((7AR)-2-IMINO-6-(6-METHOXYPYRIDIN-2- YL)-3-METHYL-4-OXOOCTAHYDRO-1H-PYRROLO[3,4-D]PYRIMIDIN-7A-YL) THIOPHEN-3-YL)BENZONITRILE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4h3g:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 2-((7AR)-7A-(4-(3-CYANOPHENYL)THIOPHEN-2- YL)-2-IMINO-3-METHYL-4-OXOHEXAHYDRO-1H-PYRROLO[3,4-D]PYRIMIDIN-6(2H)- YL)NICOTINONITRILE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4h3g:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 2-((7AR)-7A-(4-(3-CYANOPHENYL)THIOPHEN-2- YL)-2-IMINO-3-METHYL-4-OXOHEXAHYDRO-1H-PYRROLO[3,4-D]PYRIMIDIN-6(2H)- YL)NICOTINONITRILE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4h3i:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 3-(5-((7AR)-2-IMINO-6-(3-METHOXYPYRIDIN-2- YL)-3-METHYL-4-OXOOCTAHYDRO-1H-PYRROLO[3,4-D]PYRIMIDIN-7A-YL) THIOPHEN-3-YL)BENZONITRILE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4h3i:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 3-(5-((7AR)-2-IMINO-6-(3-METHOXYPYRIDIN-2- YL)-3-METHYL-4-OXOOCTAHYDRO-1H-PYRROLO[3,4-D]PYRIMIDIN-7A-YL) THIOPHEN-3-YL)BENZONITRILE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4h3j:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 2-FLUORO-5-(5-(2-IMINO-3-METHYL-4-OXO-6- PHENYLOCTAHYDRO-1H-PYRROLO[3,4-D]PYRIMIDIN-7A-YL)THIOPHEN-2-YL) BENZONITRILE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2b4k:B (THR443) to (VAL471) ACETOBACTER TURBIDANS ALPHA-AMINO ACID ESTER HYDROLASE COMPLEXED WITH PHENYLGLYCINE | ALPHA-BETA HYDROLASE, HYDROLASE
4wqt:N (ARG209) to (VAL355) THERMUS THERMOPHILUS RNA POLYMERASE COMPLEXED WITH AN RNA CLEAVAGE STIMULATING FACTOR (A GREA/GFH1 CHIMERIC PROTEIN) | TRANSCRIPTION, RNA CLEAVAGE, TRANSFERASE-TRANSCRIPTION COMPLEX
2b5r:C (SER1108) to (SER1139) 1B LACTAMASE / B LACTAMASE INHIBITOR | PROTEIN-PROTEIN COMPLEX, STRUCTURAL GENOMICS, ISRAEL STRUCTURAL PROTEOMICS CENTER, ISPC, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
4ha5:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO (S)-3-(5-(2-IMINO-1,4-DIMETHYL-6- OXOHEXAHYDROPYRIMIDIN-4-YL)THIOPHEN-3-YL)BENZONITRILE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ha8:A (GLY119) to (ARG142) STRUCTURE OF STAPHYLOCOCCUS AUREUS BIOTIN PROTEIN LIGASE IN COMPLEX WITH BIOTIN ACETYLENE | LIGASE, DNA-BINDING DOMAIN
4wst:A (GLY286) to (GLY319) THE CRYSTAL STRUCTURE OF HEMAGGLUTININ FROM A/TAIWAN/1/2013 INFLUENZA VIRUS | HEMAGGLUTININ, INFLUENZA VIRUS, H6, VIRAL PROTEIN
4wtu:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH 2-AMINOOXAZOLINE 3-AZA-4- FLUORO-XANTHENE INHIBITOR 22 | ASPARTIC PROTEASE, AMYLOID PRECURSOR PROTEIN, ALZHEIMER'S DISEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1nxj:A (VAL132) to (ASP150) STRUCTURE OF RV3853 FROM MYCOBACTERIUM TUBERCULOSIS | BETA/BETA/ALPHA DOMAIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, UNKNOWN FUNCTION
1nxj:B (VAL132) to (ASP150) STRUCTURE OF RV3853 FROM MYCOBACTERIUM TUBERCULOSIS | BETA/BETA/ALPHA DOMAIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, UNKNOWN FUNCTION
1nxj:C (VAL132) to (ASP150) STRUCTURE OF RV3853 FROM MYCOBACTERIUM TUBERCULOSIS | BETA/BETA/ALPHA DOMAIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, UNKNOWN FUNCTION
2p4j:D (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SECRETASE BOND TO AN INHIBITOR WITH ISOPHTHALAMIDE DERIVATIVES AT P2-P3 | BETA-SECRETASE, MEMAPSIN, BACE, ASP, ASPARTIC PROTEASE, ACID PROTEASE, ALZHEIMER'S DISEASE, DRUG DESIGN, STRUCTURE BASED DRUG DESIGN, HYDROLASE
2bco:A (PHE293) to (ILE310) X-RAY STRUCTURE OF SUCCINYLGLUTAMATE DESUCCINALASE FROM VIBRIO PARAHAEMOLYTICUS (RIMD 2210633) AT THE RESOLUTION 2.3 A, NORTHEAST STRUCTURAL GENOMICS TARGET VPR14 | NESG, VPR14, X-RAY STRUCTURE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, HYDROLASE
4wy1:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BACE-1 BOUND TO COMPOUND 24B | BETA SECRETASE BACE PROTEASE
4wy6:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BACE-1 BOUND TO COMPOUND 36 | BACE BETA SECRETASE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4hfj:B (ALA2) to (PRO54) X-RAY CRYSTAL STRUCTURE OF A DOUBLE BOND REDUCTASE FROM NICOTIANA TABACUM | ROSSMANN FOLD, TWISTED B-BARREL, ALKENE REDUCTION, OXIDOREDUCTASE
2p83:A (TYR342) to (PRO373) POTENT AND SELECTIVE ISOPHTHALAMIDE S2 HYDROXYETHYLAMINE INHIBITOR OF BACE1 | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
1b98:M (ARG28) to (CYS61) NEUROTROPHIN 4 (HOMODIMER) | TARGET-DERIVED SURVIVAL FACTOR, NEUROTROPHIN 4, NEUROTROPHIN 5, HORMONE/GROWTH FACTOR COMPLEX
4hhy:B (VAL287) to (LYS349) CRYSTAL STRUCTURE OF PARP CATALYTIC DOMAIN IN COMPLEX WITH NOVEL INHIBITORS | POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4hhz:B (VAL287) to (PHE348) CRYSTAL STRUCTURE OF PARP CATALYTIC DOMAIN IN COMPLEX WITH NOVEL INHIBITORS | POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4hhz:C (VAL287) to (PHE348) CRYSTAL STRUCTURE OF PARP CATALYTIC DOMAIN IN COMPLEX WITH NOVEL INHIBITORS | POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3s2o:A (TYR342) to (PRO373) FRAGMENT BASED DISCOVERY AND OPTIMISATION OF BACE-1 INHIBITORS | PROTEASE, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, MEMAPSIN 2, AMYLOID PRECURSOR PROTEIN SECRETASES, ASPARTIC ENDOPEPTIDASES, FRAGMENT-BASED DRUG DESIGN, FLUORESCENCE POLARISATION, TRANSMEMBRANE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
2pcf:B (TYR146) to (ASN167) THE COMPLEX OF CYTOCHROME F AND PLASTOCYANIN DETERMINED WITH PARAMAGNETIC NMR. BASED ON THE STRUCTURES OF CYTOCHROME F AND PLASTOCYANIN, 10 STRUCTURES | ELECTRON TRANSPORT, PARAMAGNETIC, CHEMICAL SHIFT, COMPLEX FORMATION, DYNAMIC COMPLEX, PHOTOSYNTHESIS, PSEUDOCONTACT SHIFT, COMPLEX (ELECTRON TRANSPORT PROTEINS)
4x2l:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BACE-1 BOUND TO COMPOUND 6 | BETA-SECRETASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2pcn:A (VAL129) to (ASP147) CRYSTAL STRUCTURE OF S-ADENOSYLMETHIONINE: 2-DIMETHYLMENAQUINONE METHYLTRANSFERASE (GK_1813) FROM GEOBACILLUS KAUSTOPHILUS HTA426 | BETA, BETA ALPHA DOMAIN, 2-DIMETHYLMENAQUINONE METHYLTRANSFERASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
1bjn:B (PRO150) to (ALA173) STRUCTURE OF PHOSPHOSERINE AMINOTRANSFERASE FROM ESCHERICHIA COLI | AMINOTRANSFERASE, L-SERINE BIOSYNTHESIS
1blb:A (HIS88) to (SER111) CLOSE PACKING OF AN OLIGOMERIC EYE LENS BETA-CRYSTALLIN INDUCES LOSS OF SYMMETRY AND ORDERING OF SEQUENCE EXTENSIONS | EYE LENS PROTEIN
1o60:C (GLN2) to (MSE25) CRYSTAL STRUCTURE OF KDO-8-PHOSPHATE SYNTHASE | STRUCTURAL GENOMICS, TRANSFERASE
3s5u:A (ARG2) to (LYS23) CRYSTAL STRUCTURE OF CRISPR ASSOCIATED PROTEIN | CRISPR, CRISPR ADAPTATION MECHANISM, NEW SPACER AQUISITION, DSDNA BINDING, DNA BINDING PROTEIN
3s5u:D (ARG2) to (ILE22) CRYSTAL STRUCTURE OF CRISPR ASSOCIATED PROTEIN | CRISPR, CRISPR ADAPTATION MECHANISM, NEW SPACER AQUISITION, DSDNA BINDING, DNA BINDING PROTEIN
3s5u:G (ARG2) to (ASP24) CRYSTAL STRUCTURE OF CRISPR ASSOCIATED PROTEIN | CRISPR, CRISPR ADAPTATION MECHANISM, NEW SPACER AQUISITION, DSDNA BINDING, DNA BINDING PROTEIN
4x67:B (ARG497) to (SER546) CRYSTAL STRUCTURE OF ELONGATING YEAST RNA POLYMERASE II STALLED AT OXIDATIVE CYCLOPURINE DNA LESIONS. | POL II ELONGATION COMPLEX OXIDATIVE CYCLOPURINE DNA LESIONS, TRANSCRIPTION-DNA COMPLEX
4x7i:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE WITH AMINO THIAZINE INHIBITOR LY2886721 | BACE, BETA-SECRETASE, INHIBITOR, COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3sav:A (HIS95) to (VAL119) MUTM SLANTED COMPLEX 8 | DNA GLYCOSYLASE, DNA REPAIR, DAMAGE SEARCH, TRANSLOCATION, DISULFIDE CROSSLINKING, DNA DAMAGE, DNA-BINDING, GLYCOSIDASE, HYDROLASE, LYASE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, ZINC-FINGER, HYDROLASE-DNA COMPLEX
1ocj:A (GLY359) to (LYS399) MUTANT D416A OF THE CELLOBIOHYDROLASE CEL6A FROM HUMICOLA INSOLENS IN COMPLEX WITH A THIOPENTASACCHARIDE AT 1.3 ANGSTROM RESOLUTION | HYDROLASE, CELLULOSE DEGRADATION, PROCESSIVE MECHANISM GLYCOSIDE HYDROLASE FAMILY 6
4xbb:A (ALA48) to (GLU75) 1.85A RESOLUTION STRUCTURE OF NOROVIRUS 3CL PROTEASE COMPLEX WITH A COVALENTLY BOUND DIPEPTIDYL INHIBITOR DIETHYL [(1R,2S)-2-[(N-{[(3- CHLOROBENZYL)OXY]CARBONYL}-3-CYCLOHEXYL-L-ALANYL)AMINO]-1-HYDROXY-3- (2-OXO-2H-PYRROL-3-YL)PROPYL]PHOSPHONATE | PROTEASE, NOROVIRUS, NORWALK VIRUS, ANTIVIRAL INHIBITORS, DIPEPTIDYL INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4xbc:A (ALA48) to (GLU75) 1.60 A RESOLUTION STRUCTURE OF NOROVIRUS 3CL PROTEASE COMPLEX WITH A COVALENTLY BOUND DIPEPTIDYL INHIBITOR (1R,2S)-2-({N-[(BENZYLOXY) CARBONYL]-3-CYCLOHEXYL-L-ALANYL}AMINO)-1-HYDROXY-3-[(3S)-2- OXOPYRROLIDIN-3-YL]PROPANE-1-SULFONIC ACID (HEXAGONAL FORM) | PROTEASE, NOROVIRUS, NORWALK VIRUS, ANTIVIRAL INHIBITORS, DIPEPTIDYL INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2bvj:B (GLU300) to (LEU319) LIGAND-FREE STRUCTURE OF CYTOCHROME P450 PIKC (CYP107L1) | CYTOCHROME P450, PIKC, CYP107L1, MACROLIDE MONOOXYGENASE, ANTIBIOTIC BIOSYNTHESIS, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE
2ph8:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE COMPLEXED WITH INHIBITOR | ASPARTYL PROTEASE, BACE, HYDROLASE
2plm:A (ALA370) to (THR386) CRYSTAL STRUCTURE OF THE PROTEIN TM0936 FROM THERMOTOGA MARITIMA COMPLEXED WITH ZN AND S-INOSYLHOMOCYSTEINE | TM0936, FUNCTION PREDICTION, AMIDOHYDROLASE, UNKNOWN FUNCTION
4hyv:A (ARG171) to (PRO188) PYRUVATE KINASE (PYK) FROM TRYPANOSOMA BRUCEI IN THE PRESENCE OF MAGNESIUM, PEP AND F26BP | ALLOSTERIC REGULATION, TETRAMER, PYRUVATE KINASE, FRUCTOSE-2,6- DIPHOSPHATE BINDING, PHOSPHOENOLPYRUVATE BINDING, CYTOSOL, TRANSFERASE
4xe3:A (GLU302) to (PHE321) OLEP, THE CYTOCHROME P450 EPOXIDASE FROM STREPTOMYCES ANTIBIOTICUS INVOLVED IN OLEANDOMYCIN BIOSYNTHESIS: FUNCTIONAL ANALYSIS AND CRYSTALLOGRAPHIC STRUCTURE IN COMPLEX WITH CLOTRIMAZOLE. | P450, CLOTRIMAZOLE, EPOXIDASE, OLEANDOMYCIN, OXIDOREDUCTASE
2bz9:B (GLU331) to (SER348) LIGAND-FREE STRUCTURE OF STEROL 14ALPHA-DEMETHYLASE FROM MYCOBACTERIUM TUBERCULOSIS IN P2(1) SPACE GROUP | STEROL 14ALPHA-DEMETHYLASE, P450, ELECTRON TRANSPORT, HEME, IRON, LIPID SYNTHESIS, METAL-BINDING, MONOOXYGENASE
4i0h:B (TYR348) to (PRO379) SPR AND STRUCTURAL ANALYSIS YIELD INSIGHT TOWARDS MECHANISM OF INHIBITION OF BACE INHIBITORS. | BACE, ASP PROTEASE, HYDROLYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4i0h:C (TYR348) to (PRO379) SPR AND STRUCTURAL ANALYSIS YIELD INSIGHT TOWARDS MECHANISM OF INHIBITION OF BACE INHIBITORS. | BACE, ASP PROTEASE, HYDROLYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4i0i:A (TYR348) to (PRO379) SPR AND STRUCTURAL ANALYSIS YIELD INSIGHT TOWARDS MECHANISM OF INHIBITION OF BACE INHIBITORS | BACE, ASPARTIC PROTEASE, HYDROLYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4i0i:B (TYR348) to (PRO379) SPR AND STRUCTURAL ANALYSIS YIELD INSIGHT TOWARDS MECHANISM OF INHIBITION OF BACE INHIBITORS | BACE, ASPARTIC PROTEASE, HYDROLYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4i0i:C (TYR348) to (PRO379) SPR AND STRUCTURAL ANALYSIS YIELD INSIGHT TOWARDS MECHANISM OF INHIBITION OF BACE INHIBITORS | BACE, ASPARTIC PROTEASE, HYDROLYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4xhj:A (ASN217) to (SER245) GHGL OF VARICELLA-ZOSTER VIRUS IN COMPLEX WITH HUMAN NEUTRALIZING ANTIBODIES. | COMPLEX, NEUTRALIZATION EPITOPES, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
4xi7:A (TYR125) to (GLY150) CRYSTAL STRUCTURE OF THE MZM-REP DOMAINS OF MIND BOMB 1 IN COMPLEX WITH JAGGED1 N-BOX PEPTIDE | E3 LIGASE, NOTCH SIGNALING
4xib:A (TYR125) to (GLY150) CRYSTAL STRUCTURE OF THE MZM-REP DOMAINS OF MIND BOMB 1 IN COMPLEX WITH FLY DELTA N-BOX PEPTIDE | E3 LIGASE, NOTCH SIGNALING
3fjs:A (PRO25) to (SER50) CRYSTAL STRUCTURE OF A PUTATIVE BIOSYNTHETIC PROTEIN WITH RMLC-LIKE CUPIN FOLD (REUT_B4087) FROM RALSTONIA EUTROPHA JMP134 AT 1.90 A RESOLUTION | RMLC-LIKE CUPIN FOLD, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, BIOSYNTHETIC PROTEIN
1cb2:A (GLY355) to (LYS395) CELLOBIOHYDROLASE II, CATALYTIC DOMAIN, MUTANT Y169F | HYDROLASE (O-GLYCOSYL), GLYCOSIDASE, GLYCOPROTEIN
1cb2:B (GLY355) to (LYS395) CELLOBIOHYDROLASE II, CATALYTIC DOMAIN, MUTANT Y169F | HYDROLASE (O-GLYCOSYL), GLYCOSIDASE, GLYCOPROTEIN
1cb8:A (GLY495) to (PHE512) CHONDROITINASE AC LYASE FROM FLAVOBACTERIUM HEPARINUM | LYASE, CHONDROITIN DEGRADATION
2pso:A (LEU1015) to (MET1050) HUMAN STARD13 (DLC2) LIPID TRANSFER AND PROTEIN LOCALIZATION DOMAIN | ALPHA AND BETA PROTEIN, LIPID BINDING, HELIX SWAPPING, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, UNKNOWN FUNCTION
2pso:B (LEU1015) to (MET1050) HUMAN STARD13 (DLC2) LIPID TRANSFER AND PROTEIN LOCALIZATION DOMAIN | ALPHA AND BETA PROTEIN, LIPID BINDING, HELIX SWAPPING, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, UNKNOWN FUNCTION
1olz:A (PHE192) to (PRO230) THE LIGAND-BINDING FACE OF THE SEMAPHORINS REVEALED BY THE HIGH RESOLUTION CRYSTAL STRUCTURE OF SEMA4D | DEVELOPMENTAL PROTEIN, CD100, SEMAPHORIN, BETA-PROPELLER, PSI DOMAIN, IG-LIKE DOMAIN, EXTRACELLULAR RECEPTOR, NEUROGENESIS, GLYCOPROTEIN DEVELOPMENTAL PROTEIN, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, STRUCTURAL GENOMICS
3skg:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH (2S)-2-((3R)-3-ACETAMIDO-3-ISOBUTYL-2-OXO-1-PYRROLIDINYL)-N- ((1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-2-(1,2,3,4-TETRAHYDRO-3- ISOQUINOLINYL)ETHYL)-4-PHENYLBUTANAMIDE | ALZHEIMER'S DISEASE, BACE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3skg:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH (2S)-2-((3R)-3-ACETAMIDO-3-ISOBUTYL-2-OXO-1-PYRROLIDINYL)-N- ((1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-2-(1,2,3,4-TETRAHYDRO-3- ISOQUINOLINYL)ETHYL)-4-PHENYLBUTANAMIDE | ALZHEIMER'S DISEASE, BACE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3skg:E (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH (2S)-2-((3R)-3-ACETAMIDO-3-ISOBUTYL-2-OXO-1-PYRROLIDINYL)-N- ((1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-2-(1,2,3,4-TETRAHYDRO-3- ISOQUINOLINYL)ETHYL)-4-PHENYLBUTANAMIDE | ALZHEIMER'S DISEASE, BACE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4xkf:E (GLY286) to (GLY319) CRYSTAL STRUCTURE OF HEMAGGLUTININ FROM TAIWAN (2013) H6N1 INFLUENZA VIRUS IN COMPLEX WITH LSTA | VIRAL PROTEIN
3fnm:A (GLY86) to (THR139) CRYSTAL STRUCTURE OF ACIVICIN-INHIBITED GAMMA-GLUTAMYLTRANSPEPTIDASE REVEALS CRITICAL ROLES FOR ITS C-TERMINUS IN AUTOPROCESSING AND CATALYSIS | NTN-HYDROLASE, GLUTAMYLTRANSPEPTIDASE, TRANSFERASE
3fnm:C (GLY86) to (THR139) CRYSTAL STRUCTURE OF ACIVICIN-INHIBITED GAMMA-GLUTAMYLTRANSPEPTIDASE REVEALS CRITICAL ROLES FOR ITS C-TERMINUS IN AUTOPROCESSING AND CATALYSIS | NTN-HYDROLASE, GLUTAMYLTRANSPEPTIDASE, TRANSFERASE
2pxg:A (GLU68) to (GLN115) NMR SOLUTION STRUCTURE OF OMLA | TWO LAYER ALPHA/BETA PLAIT, TWO LAYER SANDWICH ARCHITECTURE, MEMBRANE PROTEIN
3fs2:A (SER6) to (ALA25) CRYSTAL STRUCTURE OF 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE FROM BRUCIELLA MELITENSIS AT 1.85A RESOLUTION | SSGCID, BRUCIELLLA MELITENSIS, DAHP SYNTHETASE I, 2-DEHYDRO- 3-DEOXYPHOSPHOOCTONATE ALDOLASE, CYTOPLASM, LIPOPOLYSACCHARIDE BIOSYNTHESIS, TRANSFERASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
2c7x:A (GLU300) to (LEU319) CRYSTAL STRUCTURE OF NARBOMYCIN-BOUND CYTOCHROME P450 PIKC (CYP107L1) | CYTOCHROME P450, PIKC, NARBOMYCIN, MACROLIDE MONOOXYGENASE, ANTIBIOTIC BIOSYNTHESIS, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE
3ste:B (MET1) to (GLY20) CRYSTAL STRUCTURE OF A MUTANT (Q202A) OF 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3ste:C (MET1) to (GLY20) CRYSTAL STRUCTURE OF A MUTANT (Q202A) OF 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3ste:D (MET1) to (GLY20) CRYSTAL STRUCTURE OF A MUTANT (Q202A) OF 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3stf:A (MET1) to (ILE22) CRYSTAL STRUCTURE OF A MUTANT (S211A) OF 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3stf:D (MET1) to (GLY20) CRYSTAL STRUCTURE OF A MUTANT (S211A) OF 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3stg:B (MET1) to (GLY20) CRYSTAL STRUCTURE OF A58P, DEL(N59), AND LOOP 7 TRUNCATED MUTANT OF 3- DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3stg:C (MET1) to (GLY20) CRYSTAL STRUCTURE OF A58P, DEL(N59), AND LOOP 7 TRUNCATED MUTANT OF 3- DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3stg:D (MET1) to (ILE22) CRYSTAL STRUCTURE OF A58P, DEL(N59), AND LOOP 7 TRUNCATED MUTANT OF 3- DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
2c9k:A (ASN547) to (PHE569) STRUCTURE OF THE FUNCTIONAL FORM OF THE MOSQUITO-LARVICIDAL CRY4AA TOXIN FROM BACILLUS THURINGIENSIS AT 2.8 A RESOLUTION | TOXIN, INSECT TOXIN, BIOINSECTICICIDE, PORE FORMATION, RECEPTOR RECOGNITION, SPORULATION
3fyp:D (MET1) to (GLY20) CRYSTAL STRUCTURE OF THE QUADRUPLE MUTANT (N23C/C246S/D247E/P249A) OF 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
2cd8:B (GLU300) to (LEU319) CRYSTAL STRUCTURE OF YC-17-BOUND CYTOCHROME P450 PIKC (CYP107L1) | OXIDOREDUCTASE, CYTOCHROME P450, PIKC, YC-17, MACROLIDE MONOOXYGENASE, ANTIBIOTIC BIOSYNTHESIS, HEME, IRON, METAL-BINDING
3swr:A (TYR924) to (PRO942) STRUCTURE OF HUMAN DNMT1 (601-1600) IN COMPLEX WITH SINEFUNGIN | EPIGENETICS, DNA METHYLTRANSFERASE FOLD, MAINTENANCE METHYLATION, TRANSFERASE
1d1s:C (ASN142) to (ASP161) WILD-TYPE HUMAN SIGMA (CLASS IV) ALCOHOL DEHYDROGENASE | ROSSMAN OR DINUCLEOTIDE FOLD, OXIDOREDUCTASE
3swz:A (ASP378) to (ASN395) HUMAN CYTOCHROME P450 17A1 IN COMPLEX WITH TOK-001 | CYTOCHROME P450, P450, CYP17A1, P450C17, P450 17A1, MONOOXYGENASE, 17A-HYDROXYLASE, 17,20-LYASE, HEME PROTEIN, CYTOCHROME P450 OXIDOREDUCTASE, GALETERONE, MEMBRANE, TOK-001, VN/124-1, MICROSOME, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
2qdf:A (SER148) to (GLY184) STRUCTURE OF N-TERMINAL DOMAIN OF E. COLI YAET | POTRA DOMAIN, MEMBRANE PROTEIN, PROTEIN TRANSPORT
2cgh:A (GLY244) to (LEU265) CRYSTAL STRUCTURE OF BIOTIN LIGASE FROM MYCOBACTERIUM TUBERCULOSIS | BIOTIN LIGASE, MYCOBACTERIUM TUBERCULOSIS, LIGASE
2cgh:B (GLY244) to (LEU265) CRYSTAL STRUCTURE OF BIOTIN LIGASE FROM MYCOBACTERIUM TUBERCULOSIS | BIOTIN LIGASE, MYCOBACTERIUM TUBERCULOSIS, LIGASE
3sz8:A (SER0) to (ILE23) CRYSTAL STRUCTURE OF 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE FROM BURKHOLDERIA PSEUDOMALLEI | SSGCID, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
1d7y:A (HIS90) to (LEU107) CRYSTAL STRUCTURE OF NADH-DEPENDENT FERREDOXIN REDUCTASE, BPHA4 | FLAVOPROTEIN ROSSMANN FOLD, OXIDOREDUCTASE
1d8t:A (GLY257) to (ALA270) CRYSTAL STRUCTURE OF ELONGATION FACTOR, TU (EF-TU-MGGDP) COMPLEXED WITH GE2270A, A THIAZOLYL PEPTIDE ANTIBIOTIC | HYDROLASE-ANTIBIOTIC COMPLEX, THIOPEPTIDE, ANTIBIOTIC, ANTIBACTERIAL, THIAZOLE, OXAZOLE, HYDROLASE, GTPASE, TRANSLATION ELONGATION FACTOR, PROTEIN SYNTHESIS, NUCLEOTIDE-BINDING, PHOSPHORYLATION
1d8t:B (GLY257) to (ALA270) CRYSTAL STRUCTURE OF ELONGATION FACTOR, TU (EF-TU-MGGDP) COMPLEXED WITH GE2270A, A THIAZOLYL PEPTIDE ANTIBIOTIC | HYDROLASE-ANTIBIOTIC COMPLEX, THIOPEPTIDE, ANTIBIOTIC, ANTIBACTERIAL, THIAZOLE, OXAZOLE, HYDROLASE, GTPASE, TRANSLATION ELONGATION FACTOR, PROTEIN SYNTHESIS, NUCLEOTIDE-BINDING, PHOSPHORYLATION
2qez:A (ILE141) to (ARG160) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE HEAVY CHAIN (YP_013784.1) FROM LISTERIA MONOCYTOGENES 4B F2365 AT 2.15 A RESOLUTION | YP_013784.1, ETHANOLAMINE AMMONIA-LYASE HEAVY CHAIN, ETHANOLAMINE AMMONIA LYASE LARGE SUBUNIT (EUTB), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
2qez:B (ILE141) to (ARG160) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE HEAVY CHAIN (YP_013784.1) FROM LISTERIA MONOCYTOGENES 4B F2365 AT 2.15 A RESOLUTION | YP_013784.1, ETHANOLAMINE AMMONIA-LYASE HEAVY CHAIN, ETHANOLAMINE AMMONIA LYASE LARGE SUBUNIT (EUTB), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
2qez:C (ILE141) to (ARG160) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE HEAVY CHAIN (YP_013784.1) FROM LISTERIA MONOCYTOGENES 4B F2365 AT 2.15 A RESOLUTION | YP_013784.1, ETHANOLAMINE AMMONIA-LYASE HEAVY CHAIN, ETHANOLAMINE AMMONIA LYASE LARGE SUBUNIT (EUTB), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
2qez:E (ILE141) to (ARG160) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE HEAVY CHAIN (YP_013784.1) FROM LISTERIA MONOCYTOGENES 4B F2365 AT 2.15 A RESOLUTION | YP_013784.1, ETHANOLAMINE AMMONIA-LYASE HEAVY CHAIN, ETHANOLAMINE AMMONIA LYASE LARGE SUBUNIT (EUTB), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
2qez:F (ILE141) to (ARG160) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE HEAVY CHAIN (YP_013784.1) FROM LISTERIA MONOCYTOGENES 4B F2365 AT 2.15 A RESOLUTION | YP_013784.1, ETHANOLAMINE AMMONIA-LYASE HEAVY CHAIN, ETHANOLAMINE AMMONIA LYASE LARGE SUBUNIT (EUTB), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
4xqm:A (MET363) to (GLN384) CRYSTAL STRUCTURE OF THE MRH DOMAIN OF GLUCOSIDASE II BETA BOUND TO MANNOSE | HYDROLASE, SUGAR BINDING PROTEIN
2qi9:D (VAL4) to (PRO34) ABC-TRANSPORTER BTUCD IN COMPLEX WITH ITS PERIPLASMIC BINDING PROTEIN BTUF | INNER MEMBRANE, MEMBRANE, TRANSMEMBRANE, TRANSPORT, ATP- BINDING, HYDROLASE, NUCLEOTIDE-BINDING, PERIPLASM, MEMBRANE PROTEIN
4imq:A (ALA48) to (GLU75) STRUCTURAL BASIS OF SUBSTRATE SPECIFICITY AND PROTEASE INHIBITION IN NORWALK VIRUS | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4imz:A (ALA48) to (GLU75) STRUCTURAL BASIS OF SUBSTRATE SPECIFICITY AND PROTEASE INHIBITION IN NORWALK VIRUS | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4in2:A (ALA48) to (GLU74) STRUCTURAL BASIS OF SUBSTRATE SPECIFICITY AND PROTEASE INHIBITION IN NORWALK VIRUS | PROTEASE, HYDROLASE
4inh:C (ALA48) to (GLU75) STRUCTURAL BASIS OF SUBSTRATE SPECIFICITY AND PROTEASE INHIBITION IN NORWALK VIRUS | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4inh:H (ALA48) to (GLU75) STRUCTURAL BASIS OF SUBSTRATE SPECIFICITY AND PROTEASE INHIBITION IN NORWALK VIRUS | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1dg1:H (GLY257) to (ALA270) WHOLE, UNMODIFIED, EF-TU(ELONGATION FACTOR TU). | ELONGATION FACTOR, TRNA BINDING, ALPHA BETA SHIFT, TS BINDING PROTEIN, GTPASE, GDP BINDING, RNA BINDING PROTEIN
3g6o:B (ALA28) to (PRO55) CRYSTAL STRUCTURE OF P. AERUGINOSA BACTERIOPHYTOCHROME PABPHP PHOTOSENSORY CORE DOMAIN MUTANT Q188L | ALPHA/BETA STRUCTURE, PAS DOMAIN, CHROMOPHORE, KINASE, PHOSPHOPROTEIN, PHOTORECEPTOR PROTEIN, RECEPTOR, SENSORY TRANSDUCTION, TRANSFERASE, SIGNALING PROTEIN
2qk5:A (TYR403) to (PRO434) STRUCTURE OF BACE1 BOUND TO SCH626485 | BACE1, PROTEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
2qkf:A (MET1) to (ILE22) CRYSTAL STRUCTURE OF 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, LIPOPOLYSACCHARIDE BIOSYNTHESIS, TRANSFERASE, LYASE
2qkf:B (MET1) to (GLY20) CRYSTAL STRUCTURE OF 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, LIPOPOLYSACCHARIDE BIOSYNTHESIS, TRANSFERASE, LYASE
2qkf:D (MET1) to (GLY20) CRYSTAL STRUCTURE OF 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, LIPOPOLYSACCHARIDE BIOSYNTHESIS, TRANSFERASE, LYASE
2qm6:A (GLY86) to (THR139) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI GAMMA-GLUTAMYLTRANSPEPTIDASE IN COMPLEX WITH GLUTAMATE | NTN-HYDROLASE, GLUTAMYLTRANSPEPTIDASE, TRANSFERASE
2qmc:A (GLY86) to (THR139) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI GAMMA-GLUTAMYLTRANSPEPTIDASE T380A MUTANT | NTN-HYDROLASE, GLUTAMYLTRANSPEPTIDASE, TRANSFERASE
2qmd:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH722924 | BACE1, PROTEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
2qmd:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH722924 | BACE1, PROTEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
2qmf:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH735310 | BACE1, PROTEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
2qmf:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH735310 | BACE1, PROTEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
2qmg:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH745966 | BACE1, PROTEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
1pht:A (GLY54) to (GLY78) PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT SH3 DOMAIN, RESIDUES 1-85 | PHOSPHATIDYLINOSITOL 3-KINASE, P85-ALPHA SUBUNIT, SH3 DOMAIN, PHOSPHOTRANSFERASE
4xtu:B (GLY66) to (VAL91) MYCOBACTERIUM TUBERCULOSIS BIOTIN LIGASE COMPLEXED WITH BISUBSTRATE INHIBITOR (N-({[(1R,2S,3R,4R)-4-(6-AMINO-9H-PURIN-9-YL)-2,3- DIHYDROXYCYCLOPENTYL]METHYL}SULFAMOYL)-5-[(3AS,4S,6AR)-2- OXOHEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL]PENTANAMIDE) | BIOTIN-PROTEIN LIGASE, BISUBSTRATE INHIBITOR, LIGASE-LIGASE INHIBITOR COMPLEX
4xtv:B (GLY66) to (ARG89) MYCOBACTERIUM TUBERCULOSIS BIOTIN LIGASE COMPLEXED WITH BISUBSTRATE INHIBITOR 36 (N-({[(1R,3S)-3-(6-AMINO-9H-PURIN-9-YL) CYCLOPENTYL]METHYL}SULFAMOYL)-5-[(3AS,4S,6AR)-2-OXOHEXAHYDRO-1H- THIENO[3,4-D]IMIDAZOL-4-YL]PENTANAMIDE) | BIOTIN-PROTEIN LIGASE, BISUBSTRATE INHIBITOR, LIGASE-LIGASE INHIBITOR COMPLEX
4xtx:A (GLY66) to (ARG89) MYCOBACTERIUM TUBERCULOSIS BIOTIN LIGASE COMPLEXED WITH BISUBSTRATE INHIBITOR 57 WITH AZIDE IN PLACE OF RIBOSE 2'OH | BIOTIN-PROTEIN LIGASE, BISUBSTRATE INHIBITOR, LIGASE-LIGASE INHIBITOR COMPLEX
4xu1:A (GLY66) to (ARG89) MYCOBACTERIUM TUBERCULOSIS BIOTIN LIGASE COMPLEXED WITH BISUBSTRATE INHIBITOR 82 THAT INCORPORATES A MORPHOLINE IN PLACE OF THE RIBOSE | BIOTIN-PROTEIN LIGASE, BISUBSTRATE INHIBITOR, LIGASE-LIGASE INHIBITOR COMPLEX
4xu1:B (GLY66) to (ARG89) MYCOBACTERIUM TUBERCULOSIS BIOTIN LIGASE COMPLEXED WITH BISUBSTRATE INHIBITOR 82 THAT INCORPORATES A MORPHOLINE IN PLACE OF THE RIBOSE | BIOTIN-PROTEIN LIGASE, BISUBSTRATE INHIBITOR, LIGASE-LIGASE INHIBITOR COMPLEX
4xu3:B (GLY66) to (VAL91) MYCOBACTERIUM TUBERCULOSIS BIOTIN LIGASE COMPLEXED WITH BISUBSTRATE INHIBITOR 90 THAT HAS AN ACYCLIC ETHER IN PLACE OF THE RIBOSE | BIOTIN-PROTEIN LIGASE, BISUBSTRATE INHIBITOR, LIGASE-LIGASE INHIBITOR COMPLEX
2qne:A (ALA68) to (PHE90) CRYSTAL STRUCTURE OF PUTATIVE METHYLTRANSFERASE (ZP_00558420.1) FROM DESULFITOBACTERIUM HAFNIENSE Y51 AT 2.30 A RESOLUTION | ZP_00558420.1, PUTATIVE METHYLTRANSFERASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNCHARACTERIZED PROTEIN, UNKNOWN FUNCTION, TRANSFERASE
2qp8:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH734723 | BACE1, PROTEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
2qp8:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH734723 | BACE1, PROTEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
3t4c:A (GLY-1) to (THR20) CRYSTAL STRUCTURE OF 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE FROM BURKHOLDERIA AMBIFARIA | SSGCID, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
3t4c:C (GLY-1) to (VAL22) CRYSTAL STRUCTURE OF 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE FROM BURKHOLDERIA AMBIFARIA | SSGCID, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
4xxs:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 WITH A PYRAZOLE-SUBSTITUTED TETRAHYDROPYRAN THIOAMIDINE | AMYLOID PRECURSOR PROTEIN SECRETASES, ASPARTIC ACID ENDOPEPTIDASES, DRUG DESIGN, STRUCTURE-ACTIVITY RELATIONSHIP
4iur:B (ASN219) to (SER246) CRYSTAL STRUCTURE OF SHH1 SAWADEE DOMAIN IN COMPLEX WITH H3K9ME3 PEPTIDE | TANDEM TUDOR, ZINC FINGER, H3K9ME3, MEDIATE INTERACTION, HISTONE, METHYLATION, GENE REGULATION
4ivs:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 WITH ITS INHIBITOR | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2qu2:A (TYR404) to (PRO435) BACE1 WITH COMPOUND 1 | BACE1, INHIBITOR, ACYLGUANIDINE, STRUCTURE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
2qu3:A (TYR404) to (PRO435) BACE1 WITH COMPOUND 2 | BACE1, ACYLGUANIDINE, INHIBITOR, STRUCTURE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
2d09:A (GLU299) to (SER317) A ROLE FOR ACTIVE SITE WATER MOLECULES AND HYDROXYL GROUPS OF SUBSTRATE FOR OXYGEN ACTIVATION IN CYTOCHROME P450 158A2 | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP158A2, PROTON TRANSFER, DIOXYGEN ACTIVATION, OXIDOREDUCTASE
2d0e:A (GLU299) to (SER317) SUBSTRATE ASSITED IN OXYGEN ACTIVATION IN CYTOCHROME P450 158A2 | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP158A2, PROTON TRANSFER, DIOXYGEN ACTIVATION, 2-HYDROXY-1,4-NAPHTHOQUINONE, OXIDOREDUCTASE
4y28:E (VAL104) to (LYS129) THE STRUCTURE OF PLANT PHOTOSYSTEM I SUPER-COMPLEX AT 2.8 ANGSTROM RESOLUTION. | PHOTOSYNTHESIS, LIGHT HARVESTING, ANTENNA, REACTION CENTER
4j0v:A (TYR403) to (PRO434) CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-CYANO-PYRIDINE-2- CARBOXYLIC ACID [3-((4R,5R)-2-AMINO-5-FLUORO-4-METHYL-5,6-DIHYDRO-4H- [1,3]OXAZIN-4-YL)-4-FLUORO-PHENYL]-AMIDE | PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4j0y:A (TYR403) to (PRO434) CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-CYANO-PYRIDINE-2- CARBOXYLIC ACID [3-((4R,5S)-2-AMINO-5-FLUORO-4-METHYL-5,6-DIHYDRO-4H- [1,3]OXAZIN-4-YL)-4-FLUORO-PHENYL]-AMIDE | PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4j17:A (TYR403) to (PRO434) CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-CYANO-PYRIDINE-2- CARBOXYLIC ACID [3-((S)-2-AMINO-4-DIFLUOROMETHYL-5,6-DIHYDRO-4H-[1, 3]OXAZIN-4-YL)-4-FLUORO-PHENYL]-AMIDE | PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4j1f:A (TYR403) to (PRO434) CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-CYANO-PYRIDINE-2- CARBOXYLIC ACID [3-((4S,6S)-2-AMINO-4-METHYL-6-TRIFLUOROMETHYL-5,6- DIHYDRO-4H-[1,3]OXAZIN-4-YL)-4-FLUORO-PHENYL]-AMIDE | PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2qzl:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE COMPLEXED WITH IXS | ASPARTYL PROTEASE, BACE, ALTERNATIVE SPLICING, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
1e2w:B (TYR146) to (ASN167) N168F MUTANT OF CYTOCHROME F FROM CHLAMYDOMONAS REINHARDTII | ELECTRON TRANSPORT PROTEINS, INTERNAL WATER CHAIN, PHOTOSYNTHETIC FUNCTION IMPAIRED
3gph:B (ASP375) to (THR392) HUMAN CYTOCHROME P450 2E1 IN COMPLEX WITH OMEGA-IMIDAZOLYL-DECANOIC ACID | CYP2E1, P450 2E1, MONOOXYGENASE, ACETAMINOPHEN, OXIDOREDUCTASE, HEME, FATTY ACID HYDROXYLASE, METAL-BINDING
3tc2:C (SER21) to (VAL52) CRYSTAL STRUCTURE OF POTATO SERINE PROTEASE INHIBITOR. | BETA-TREFOIL FOLD, PROTEASE INHIBITOR, HYDROLASE INHIBITOR
3tcf:B (TYR510) to (ILE540) CRYSTAL STRUCTURE OF E. COLI OPPA COMPLEXED WITH ENDOGENOUS LIGANDS | PEPTIDE-BINDING PROTEIN, PROTEIN TRANSPORT, PEPTIDE TRANSPORT, ABC TRANSPORTER
2dbw:A (GLY97) to (THR150) CRYSTAL STRUCTURE OF GAMMA-GLUTAMYLTRANSPEPTIDASE FROM ESCHERICHIA COLI ACYL-ENZYME INTERMEDIATE | GAMMA-GLUTAMYLTRANSFERASE, GGT, GAMMA-GTP, GLUTATHIONE, ACYL-ENZYME INTERMEDIATE, TRANSFERASE
2dbw:C (GLY97) to (THR150) CRYSTAL STRUCTURE OF GAMMA-GLUTAMYLTRANSPEPTIDASE FROM ESCHERICHIA COLI ACYL-ENZYME INTERMEDIATE | GAMMA-GLUTAMYLTRANSFERASE, GGT, GAMMA-GTP, GLUTATHIONE, ACYL-ENZYME INTERMEDIATE, TRANSFERASE
2r55:A (LEU119) to (HIS154) HUMAN STAR-RELATED LIPID TRANSFER PROTEIN 5 | ALPHA AND BETA PROTEIN, CHOLESTEROL BINDING, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, LIPID TRANSPORT, LIPID-BINDING, TRANSPORT, TRANSPORT PROTEIN
2de0:X (GLY538) to (ILE562) CRYSTAL STRUCTURE OF HUMAN ALPHA 1,6-FUCOSYLTRANSFERASE, FUT8 | FUT8, FUCOSYLTRANSFERASE, GLYCOSYLTRANSFERASE, N-GLYCAN, CORE FUCOSE, SH3 DOMAIN, TRANSFERASE
2r5h:C (TYR49) to (PRO78) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 16 | CAPSID, PENTAMER, PROTEIN, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID PROTEIN, VIRION, VIRAL PROTEIN
2r5i:L (TYR49) to (PRO78) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 18 | HPV18, PENTAMER, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID, CAPSID PROTEIN, VIRION, VIRAL PROTEIN
3teh:B (GLU281) to (ILE300) CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS PHENYLALANYL-TRNA SYNTHETASE COMLEXED WITH L-DOPA | AARS, L-DOPA, TRNA, LIGASE
3gtg:B (ARG497) to (ILE545) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 12MER RNA | TRANSCRIPTION, TRANSFERASE/DNA-RNA HYBRID, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, TRANSFERASE/DNA/RNA HYBRID COMPLEX
3tfc:B (THR105) to (GLY124) 1.95 ANGSTROM CRYSTAL STRUCTURE OF A BIFUNCTIONAL 3-DEOXY-7- PHOSPHOHEPTULONATE SYNTHASE/CHORISMATE MUTASE (AROA) FROM LISTERIA MONOCYTOGENES EGD-E IN COMPLEX WITH PHOSPHOENOLPYRUVATE | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, (BETA/ALPHA) BARREL, TIM BARREL, TRANSFERASE- ISOMERASE COMPLEX
3gtj:B (ARG497) to (ILE545) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 13MER RNA | TRANSCRIPTION, TRANSFERASE/DNA-RNA HYBRID, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR
3gtk:B (ARG497) to (ILE545) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 18MER RNA | TRANSCRIPTION, TRANSFERASE/DNA-RNA HYBRID, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR
1e8u:A (GLU401) to (PRO423) STRUCTURE OF THE MULTIFUNCTIONAL PARAMYXOVIRUS HEMAGGLUTININ-NEURAMINIDASE | SIALIDASE, NEURAMINIDASE, HYDROLASE, HEMAGGLUTININ
1e8v:A (GLU401) to (PRO423) STRUCTURE OF THE MULTIFUNCTIONAL PARAMYXOVIRUS HEMAGGLUTININ-NEURAMINIDASE | SIALIDASE, NEURAMINIDASE, HEMAGGLUTININ, HYDROLASE
1e8v:B (GLU401) to (PRO423) STRUCTURE OF THE MULTIFUNCTIONAL PARAMYXOVIRUS HEMAGGLUTININ-NEURAMINIDASE | SIALIDASE, NEURAMINIDASE, HEMAGGLUTININ, HYDROLASE
4j9i:E (GLU98) to (ASN120) CRYSTAL STRUCTURE OF THE ABL-SH3 DOMAIN COMPLEXED WITH THE DESIGNED HIGH-AFFINITY PEPTIDE LIGAND P17 | BETA SHANDWICH, SH3 DOMAIN, KINASE, POLY PROLINE RICH MOTIFS, TRANSFERASE-UNKNOWN FUNCTION COMPLEX
4j9o:A (PRO33) to (ARG61) HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: PRIMER EXTENSION AFTER A T:G MISPAIR | IMMUNOGLOBULIN, A TO G TRANSITION, MISINCORPORATION, WOBBLE BASE PAIR, DNA POLYMERASE, TRANSFERASE-DNA COMPLEX
1q3n:A (LYS4) to (MET25) CRYSTAL STRUCTURE OF KDO8P SYNTHASE IN ITS BINARY COMPLEX WITH SUBSTRATE PEP | BETA-ALPHA-BARRELS, LYASE, LIPOPOLYSACCHARIDE, PHOSPHOENOLPYRUVATE, TRANSFERASE
2dkg:B (GLY45) to (SER67) CRYSTAL STRUCTURE OF BIOTIN PROTEIN LIGASE FROM PYROCOCCUS HORIKOSHII OT3 IN COMPLEX WITH BIOTINYL-5'-AMP, PYROPHOSPHATE AND MG(2+) | BIOTIN BIOSYNTHESIS, DIMER, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LIGASE
3gtp:B (ARG497) to (ILE545) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 24MER RNA | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA- DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, TRANSFERASE/DNA-RNA HYBRID COMPLEX
2dm1:A (ASN15) to (ILE34) SOLUTION STRUCTURE OF THE SECOND SH3 DOMAIN OF HUMAN PROTEIN VAV-2 | RHO FAMILY GUANINE NUCLEOTIDE EXCHANGE FACTOR, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, SIGNALING PROTEIN
1ecb:A (PRO87) to (ASN106) ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE COMPLEXED WITH 2 GMP, 1 MG PER SUBUNIT | TRANSFERASE, GLUTAMINE AMIDOTRANSFERASE, PURINE BIOSYNTHESIS, GLYCOSYLTRANSFERASE, GMP, GUANINE 5'- MONOPHOSPHATE
1ecb:B (PRO87) to (ASN106) ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE COMPLEXED WITH 2 GMP, 1 MG PER SUBUNIT | TRANSFERASE, GLUTAMINE AMIDOTRANSFERASE, PURINE BIOSYNTHESIS, GLYCOSYLTRANSFERASE, GMP, GUANINE 5'- MONOPHOSPHATE
1ecb:C (PRO87) to (ASN106) ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE COMPLEXED WITH 2 GMP, 1 MG PER SUBUNIT | TRANSFERASE, GLUTAMINE AMIDOTRANSFERASE, PURINE BIOSYNTHESIS, GLYCOSYLTRANSFERASE, GMP, GUANINE 5'- MONOPHOSPHATE
1ecb:D (PRO87) to (ASN106) ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE COMPLEXED WITH 2 GMP, 1 MG PER SUBUNIT | TRANSFERASE, GLUTAMINE AMIDOTRANSFERASE, PURINE BIOSYNTHESIS, GLYCOSYLTRANSFERASE, GMP, GUANINE 5'- MONOPHOSPHATE
1ecc:A (PRO87) to (ASN106) ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE COMPLEXED WITH MN-CPRPP AND 5-OXO- NORLEUCINE | TRANSFERASE, GLUTAMINE AMIDOTRANSFERASE, PURINE BIOSYNTHESIS, GLYCOSYLTRANSFERASE
1ecf:A (PRO87) to (ASN106) ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE | PURINE BIOSYNTHESIS, TRANSFERASE, GLYCOSYLTRANSFERASE, GLUTAMINE AMIDOTRANSFERASE, TRANSFERASE (GLUTAMINE AMIDOTRANSFERASE)
1ecf:B (PRO87) to (ASN106) ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE | PURINE BIOSYNTHESIS, TRANSFERASE, GLYCOSYLTRANSFERASE, GLUTAMINE AMIDOTRANSFERASE, TRANSFERASE (GLUTAMINE AMIDOTRANSFERASE)
1ecg:A (PRO87) to (ASN106) DON INACTIVATED ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE | PURINE BIOSYNTHESIS, TRANSFERASE, GLYCOSYLTRANSFERASE, GLUTAMINE AMIDOTRANSFERASE, TRANSFERASE (GLUTAMINE AMIDOTRANSFERASE)
1ecg:B (PRO87) to (ASN106) DON INACTIVATED ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE | PURINE BIOSYNTHESIS, TRANSFERASE, GLYCOSYLTRANSFERASE, GLUTAMINE AMIDOTRANSFERASE, TRANSFERASE (GLUTAMINE AMIDOTRANSFERASE)
1ecj:B (GLN86) to (ASN106) ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE COMPLEXED WITH 2 AMP PER TETRAMER | TRANSFERASE, GLUTAMINE AMIDOTRANSFERASE, PURINE BIOSYNTHESIS, GLYCOSYLTRANSFERASE, AMP, ADENINE 5'- MONOPHOSPHATE
4y97:C (VAL270) to (PRO298) CRYSTAL STRUCTURE OF HUMAN POL ALPHA B-SUBUNIT IN COMPLEX WITH C- TERMINAL DOMAIN OF CATALYTIC SUBUNIT | HUMAN DNA POLYMERASE ALPHA, TRANSFERASE
4y97:G (VAL270) to (PRO298) CRYSTAL STRUCTURE OF HUMAN POL ALPHA B-SUBUNIT IN COMPLEX WITH C- TERMINAL DOMAIN OF CATALYTIC SUBUNIT | HUMAN DNA POLYMERASE ALPHA, TRANSFERASE
1q7q:A (PHE301) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM T. MARITIMA (OXIDIZED, ORTHORHOMBIC) | HOMOCYSTEINE, METHIONINE, FOLATE, COBALAMIN, VITAMIN B12, TRANSFERASE
1q7q:B (PHE301) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM T. MARITIMA (OXIDIZED, ORTHORHOMBIC) | HOMOCYSTEINE, METHIONINE, FOLATE, COBALAMIN, VITAMIN B12, TRANSFERASE
1q7z:A (ALA302) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM THERMOTOGA MARITIMA (CD2+ COMPLEX) | HOMOCYSTEINE, METHIONINE, FOLATE, COBALAMIN, VITAMIN B12, TRANSFERASE
1q7z:B (ALA302) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM THERMOTOGA MARITIMA (CD2+ COMPLEX) | HOMOCYSTEINE, METHIONINE, FOLATE, COBALAMIN, VITAMIN B12, TRANSFERASE
2dqw:A (ARG15) to (LEU37) CRYSTAL STRUCTURE OF DIHYDROPTEROATE SYNTHASE (FOLP) FROM THERMUS THERMOPHILUS HB8 | DIHYDROPTEROATE SYNTHASE, DIMER, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
1q85:A (ALA302) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM THERMOTOGA MARITIMA (CD2+ COMPLEX, SE-MET) | HOMOCYSTEINE, METHIONINE, FOLATE, COBALAMIN, VITAMIN B12, TRANSFERASE
1q85:B (PHE301) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM THERMOTOGA MARITIMA (CD2+ COMPLEX, SE-MET) | HOMOCYSTEINE, METHIONINE, FOLATE, COBALAMIN, VITAMIN B12, TRANSFERASE
1ee8:A (ARG83) to (GLY106) CRYSTAL STRUCTURE OF MUTM (FPG) PROTEIN FROM THERMUS THERMOPHILUS HB8 | BETA SANDWICH, ZINC FINGER, HELIX TWO-TURNS HELIX, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, DNA BINDING PROTEIN
1q8a:A (PHE301) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM THERMOTOGA MARITIMA (CD2+:L-HCY COMPLEX, SE-MET) | HOMOCYSTEINE, METHIONINE, FOLATE, COBALAMIN, VITAMIN B12, TRANSFERASE
1q8a:B (ALA302) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM THERMOTOGA MARITIMA (CD2+:L-HCY COMPLEX, SE-MET) | HOMOCYSTEINE, METHIONINE, FOLATE, COBALAMIN, VITAMIN B12, TRANSFERASE
1q8j:A (ALA302) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM THERMOTOGA MARITIMA (CD2+, HCY, METHYLTETRAHYDROFOLATE COMPLEX) | HOMOCYSTEINE, METHIONINE, FOLATE, COBALAMIN, VITAMIN B12, TRANSFERASE
1q8j:B (ALA302) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM THERMOTOGA MARITIMA (CD2+, HCY, METHYLTETRAHYDROFOLATE COMPLEX) | HOMOCYSTEINE, METHIONINE, FOLATE, COBALAMIN, VITAMIN B12, TRANSFERASE
3tmh:I (GLY389) to (ASP419) CRYSTAL STRUCTURE OF DUAL-SPECIFIC A-KINASE ANCHORING PROTEIN 2 IN COMPLEX WITH CAMP-DEPENDENT PROTEIN KINASE A TYPE II ALPHA AND PDZK1 | ALPHA HELICAL BUNDLE, PDZ FOLD, ANCHORING PROTEIN, PKA, PDZ PROTEINS, MEMBRANE, TRANSPORT PROTEIN-SIGNALING PROTEIN COMPLEX
2dti:A (GLY45) to (SER67) CRYSTAL STRUCTURE OF BIOTIN PROTEIN LIGASE FROM PYROCOCCUS HORIKOSHII OT3 IN COMPLEX WITH BIOTINYL-5'-AMP, PYROPHOSPHATE AND MN(2+) | BIOTIN BIOSYNTHESIS, DIMER, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LIGASE
2dti:B (GLY45) to (LYS69) CRYSTAL STRUCTURE OF BIOTIN PROTEIN LIGASE FROM PYROCOCCUS HORIKOSHII OT3 IN COMPLEX WITH BIOTINYL-5'-AMP, PYROPHOSPHATE AND MN(2+) | BIOTIN BIOSYNTHESIS, DIMER, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LIGASE
4jhn:C (GLY267) to (ILE289) THE CRYSTAL STRUCTURE OF THE RPGR RCC1-LIKE DOMAIN | RCC1, BETA PROPELLAR, SEVEN BLADED-PROPELLER, UNKNOWN FUNCTION
4ybi:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE WITH AMINO THIAZINE INHIBITOR LY2811376 | INHIBITOR, COMPLEX, ASPARTYL, PROTEASE, BETA-SECRETASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4ybi:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE WITH AMINO THIAZINE INHIBITOR LY2811376 | INHIBITOR, COMPLEX, ASPARTYL, PROTEASE, BETA-SECRETASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3tpl:C (TYR342) to (PRO373) APO STRUCTURE OF BACE1 | HYDROLASE, MEMAPSIN 2, PROTEASE, BETA-SECRETASE 1
4jjd:A (TYR70) to (LEU91) CRYSTAL STRUCTURE OF THE N114A ABL-SH3 DOMAIN MUTANT AT PH4 | BETA SHANDWICH, SH3 DOMAIN, KINASE, POLY PROLINE RICH MOTIFS, TRANSFERASE
3tsq:A (ASP361) to (PRO385) CRYSTAL STRUCTURE OF E. COLI HYPF WITH ATP AND CARBAMOYL PHOSPHATE | ZN FINGER, NUCLEOTIDE BINDING, HYDROGENASE MATURATION FACTOR, TRANSFERASE
3h0b:A (TYR342) to (PRO373) DISCOVERY OF AMINOHETEROCYCLES AS A NOVEL BETA-SECRETASE INHIBITOR CLASS | ASPARTYL PROTEASE, ALTERNATIVE SPLICING, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3h0b:B (TYR342) to (PRO373) DISCOVERY OF AMINOHETEROCYCLES AS A NOVEL BETA-SECRETASE INHIBITOR CLASS | ASPARTYL PROTEASE, ALTERNATIVE SPLICING, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3h0b:C (TYR342) to (PRO373) DISCOVERY OF AMINOHETEROCYCLES AS A NOVEL BETA-SECRETASE INHIBITOR CLASS | ASPARTYL PROTEASE, ALTERNATIVE SPLICING, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
2dxn:B (THR200) to (PRO220) GLYCEROPHOSPHODIESTERASE FROM ENTEROBACTER AEROGENES | DOMAIN-SWAPPING, BETA-SHEET EXTENSION, METALLOENZYME, DISULFIDE, ALPHA/BETA SANDWICH, HYDROLASE
4ye6:A (ILE590) to (GLU615) THE CRYSTAL STRUCTURE OF THE INTACT HUMAN GLNRS | AMINOACYL-TRNA SYNTHETASE, CLASS I AARS, L-GLUTAMINE, LIGASE
3ttc:A (ASP361) to (PRO385) CRYSTAL STRUCTURE OF E. COLI HYPF WITH ADP AND CARBAMOYL PHOSPHATE | ZN FINGER, NUCLEOTIDE BINDING, HYDROGENASE MATURATION FACTOR, TRANSFERASE
4jk1:C (ARG528) to (THR581) X-RAY CRYSTAL STRUCTURE OF ESCHERICHIA COLI SIGMA70 HOLOENZYME IN COMPLEX WITH GUANOSINE TETRAPHOSPHATE (PPGPP) | TRANSCRIPTION, DNA, TRANSFERASE
2dza:A (VAL14) to (THR38) CRYSTAL STRUCTURE OF DIHYDROPTEROATE SYNTHASE FROM THERMUS THERMOPHILUS HB8 IN COMPLEX WITH 4-AMINOBENZOATE | DIHYDROPTEROATE SYNTHASE, DIMER, 4-AMINOBENZOATE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
2dza:B (ARG15) to (THR38) CRYSTAL STRUCTURE OF DIHYDROPTEROATE SYNTHASE FROM THERMUS THERMOPHILUS HB8 IN COMPLEX WITH 4-AMINOBENZOATE | DIHYDROPTEROATE SYNTHASE, DIMER, 4-AMINOBENZOATE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
2dzb:A (VAL14) to (LEU37) CRYSTAL STRUCTURE OF DIHYDROPTEROATE SYNTHASE FROM THERMUS THERMOPHILUS HB8 IN COMPLEX WITH 6HMPPP | DIHYDROPTEROATE SYNTHASE, DIMER, X-RAY DIFFRACTION, 6HMPPP, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
1ep1:B (CYS234) to (LEU256) CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE B | HETEROTETRAMER, OXIDOREDUCTASE
1ep2:B (CYS234) to (LEU256) CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE B COMPLEXED WITH OROTATE | HETEROTETRAMER, OXIDOREDUCTASE
2e0w:B (GLY97) to (THR150) T391A PRECURSOR MUTANT PROTEIN OF GAMMA-GLUTAMYLTRANSPEPTIDASE FROM ESCHERICHIA COLI | NTN HYDROLASE, PRECURSOR, GAMMA-GTP, POST-TRANSLATIONAL PROCESSING, MATURATION, TRANSFERASE
2e0x:A (GLY97) to (THR150) CRYSTAL STRUCTURE OF GAMMA-GLUTAMYLTRANSPEPTIDASE FROM ESCHERICHIA COLI (MONOCLINIC FORM) | GAMMA-GLUTAMYLTRANSFERASE, GGT, GAMMA-GTP
1qk0:A (GLY355) to (LYS395) CEL6A IN COMPLEX WITH M-IODOBENZYL BETA-D-GLUCOPYRANOSYL- BETA(1,4)-D-XYLOPYRANOSIDE | HYDROLASE, GLYCOSIDASE, GLYCOPROTEIN
1qk0:B (GLY355) to (LYS395) CEL6A IN COMPLEX WITH M-IODOBENZYL BETA-D-GLUCOPYRANOSYL- BETA(1,4)-D-XYLOPYRANOSIDE | HYDROLASE, GLYCOSIDASE, GLYCOPROTEIN
2rkz:D (ALA62) to (LYS85) CRYSTAL STRUCTURE OF THE SECOND AND THIRD FIBRONECTIN F1 MODULES IN COMPLEX WITH A FRAGMENT OF STAPHYLOCOCCUS AUREUS FNBPA-1 | FIBRRONECTIN, 2F13F1, BETA ZIPPER, STAPHYLOCOCCUS AUREUS, ACUTE PHASE, ALTERNATIVE SPLICING, CELL ADHESION, EXTRACELLULAR MATRIX, GLYCOPROTEIN, HEPARIN-BINDING, PHOSPHORYLATION, PYRROLIDONE CARBOXYLIC ACID, SECRETED, SULFATION, CELL WALL, PEPTIDOGLYCAN-ANCHOR, VIRULENCE
3h1w:A (GLU349) to (GLY370) CRYSTAL STRUCTURE OF MANNOSE 6-PHOSPHATE ISOMERASE BOUND WITH ZINC AND YTTRIUM | ZINC BOUND, YTTRIUM BOUND, CUPIN, ISOMERASE
3h1y:A (GLU349) to (GLY370) CRYSTAL STRUCTURE OF MANNOSE 6-PHOSPHATE ISOMERASE FROM SALMONELLA TYPHIMURIUM BOUND TO SUBSTRATE (F6P)AND METAL ATOM (ZN) | MANNOSE 6-PHOSPAPHATE ISOMERASE, F6P COMPLEX STRUCTURE, CUPIN DOMAIN
3h21:A (ASP4) to (THR29) STRUCTURAL STUDIES OF PTERIN-BASED INHIBITORS OF DIHYDROPTEROATE SYNTHASE | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h23:B (ASP4) to (LEU26) STRUCTURAL STUDIES OF PTERIN-BASED INHIBITORS OF DIHYDROPTEROATE SYNTHASE | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h24:B (ASP4) to (LEU26) STRUCTURAL STUDIES OF PTERIN-BASED INHIBITORS OF DIHYDROPTEROATE SYNTHASE | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h2a:B (ASP4) to (LEU26) STRUCTURAL STUDIES OF PTERIN-BASED INHIBITORS OF DIHYDROPTEROATE SYNTHASE | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h2c:A (ASP4) to (LEU26) STRUCTURAL STUDIES OF PTERIN-BASED INHIBITORS OF DIHYDROPTEROATE SYNTHASE | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h2e:A (ASP4) to (VAL28) STRUCTURAL STUDIES OF PTERIN-BASED INHIBITORS OF DIHYDROPTEROATE SYNTHASE | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h2e:B (ASP4) to (THR29) STRUCTURAL STUDIES OF PTERIN-BASED INHIBITORS OF DIHYDROPTEROATE SYNTHASE | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h2f:A (ASP4) to (THR29) STRUCTURAL STUDIES OF PTERIN-BASED INHIBITORS OF DIHYDROPTEROATE SYNTHASE | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h2n:B (ASP4) to (THR29) STRUCTURAL STUDIES OF PTERIN-BASED INHIBITORS OF DIHYDROPTEROATE SYNTHASE | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h2o:A (ASP4) to (THR29) STRUCTURAL STUDIES OF PTERIN-BASED INHIBITORS OF DIHYDROPTEROATE SYNTHASE | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1qos:A (ASP5) to (SER29) LECTIN UEA-II COMPLEXED WITH CHITOBIOSE | LECTIN, CARBOHYDRATE BINDING, N-ACETYLGLUCOSAMINE
3twk:A (LYS109) to (LEU133) CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA FPG | HELIX TWO TURNS HELIX, ZINC-LESS FINGER, HYDROLASE, DNA DAMAGE, DNA REPAIR, DNA-BINDING, GLYCOSIDASE, LYASE, MULTIFUNCTIONAL ENZYME
3twk:B (LYS109) to (LEU133) CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA FPG | HELIX TWO TURNS HELIX, ZINC-LESS FINGER, HYDROLASE, DNA DAMAGE, DNA REPAIR, DNA-BINDING, GLYCOSIDASE, LYASE, MULTIFUNCTIONAL ENZYME
3twl:A (LYS109) to (LEU133) CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA FPG | HELIX TWO TURNS HELIX, ZINC-LESS FINGER, HYDROLASE, DNA DAMAGE, DNA REPAIR, DNA-BINDING, GLYCOSIDASE, LYASE, MULTIFUNCTIONAL ENZYME
3twm:A (LYS109) to (LEU133) CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA FPG | HELIX TWO TURNS HELIX, ZINC-LESS FINGER, HYDROLASE, DNA DAMAGE, DNA REPAIR, DNA-BINDING, GLYCOSIDASE, LYASE, MULTIFUNCTIONAL ENZYME, DNA CONTAINING STABLE ANALOG OF ABASIC SITE, TETRAHYDRO FURAN, HYDROLASE-DNA COMPLEX
3twm:B (LYS109) to (LEU133) CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA FPG | HELIX TWO TURNS HELIX, ZINC-LESS FINGER, HYDROLASE, DNA DAMAGE, DNA REPAIR, DNA-BINDING, GLYCOSIDASE, LYASE, MULTIFUNCTIONAL ENZYME, DNA CONTAINING STABLE ANALOG OF ABASIC SITE, TETRAHYDRO FURAN, HYDROLASE-DNA COMPLEX
3two:B (VAL92) to (ASP139) THE CRYSTAL STRUCTURE OF CAD FROM HELICOBACTER PYLORI COMPLEXED WITH NADP(H) | HELICOBACTER PYLORI, CINNAMYL-ALCOHOL DEHYDROGENASE, NADP(H), OXIDOREDUCTASE
3tya:A (ASP4) to (PRO30) DIHYDROPTEROATE SYNTHASE IN COMPLEX WITH PRODUCT | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TIM BARREL, TRANSFERASE
3tya:B (ASP4) to (THR29) DIHYDROPTEROATE SYNTHASE IN COMPLEX WITH PRODUCT | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TIM BARREL, TRANSFERASE
3tyc:A (ASP4) to (PRO30) DIHYDROPTEROATE SYNTHASE IN COMPLEX WITH DHP+ | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TIM BARREL, TRANSFERASE
3tye:B (ASP4) to (VAL28) DIHYDROPTEROATE SYNTHASE IN COMPLEX WITH DHP-STZ | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TIM BARREL, TRANSFERASE
3tyw:C (GLU306) to (LEU324) CRYSTAL STRUCTURE OF CYP105N1 FROM STREPTOMYCES COELICOLOR A3(2) | P450 MONOOXYGENASE, OXIDOREDUCTASE
3tyw:D (GLU306) to (LEU324) CRYSTAL STRUCTURE OF CYP105N1 FROM STREPTOMYCES COELICOLOR A3(2) | P450 MONOOXYGENASE, OXIDOREDUCTASE
3tyz:B (MET1) to (THR24) CRYSTAL STRUCTURE OF THE YERSINIA PESTIS DIHYDROPTEROATE SYNTHETASE WITH SUBSTRATE TRANSITION STATE COMPLEX. | DIHYDROPTEROATE SYNTHASE, TRANSITION STATE COMPLEX, PABA, TIM BARREL, TRANSFERASE-TRANSFERASE SUBSTRATE COMPLEX
1f39:A (PHE141) to (PRO176) CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR C-TERMINAL DOMAIN | COOPERATIVE OPERATOR BINDING, RECA-MEDIATED SELF-CLEAVAGE, GENE REGULATION, VIRAL PROTEIN
3u0z:B (VAL508) to (GLY528) TETRAMERIZATION DYNAMICS OF THE C-TERMINUS UNDERLIES ISOFORM-SPECIFIC CAMP-GATING IN HCN CHANNELS | HELIX, BETA SHEET, TRANSPORT PROTEIN, CNMP BINDING
3u11:B (GLY638) to (GLY659) TETRAMERIZATION DYNAMICS OF THE C-TERMINUS UNDERLIES ISOFORM-SPECIFIC CAMP-GATING IN HCN CHANNELS | TRANSPORT PROTEIN
3h8i:B (SER86) to (VAL107) THE FIRST X-RAY STRUCTURE OF A SULFIDE:QUINONE OXIDOREDUCTASE: INSIGHTS INTO SULFIDE OXIDATION MECHANISM | MEMBRANE PROTEIN, ROSSMAN-LIKE FOLD, OXIDOREDUCTASE
3h8l:B (SER86) to (VAL107) THE FIRST X-RAY STRUCTURE OF A SULFIDE:QUINONE OXIDOREDUCTASE: INSIGHTS INTO SULFIDE OXIDATION MECHANISM | MEMBRANE PROTEIN, COMPLETE FORM, ROSSMAN-LIKE FOLD, OXIDOREDUCTASE
2ea3:A (ALA48) to (ALA70) CRYSTAL STRUCTURE OF CELLULOMONAS BOGORIENSIS CHYMOTRYPSIN | CELLOULOMONAS, CHYMOTRYPSIN, PROTEASE, HYDROLASE
4jte:A (MET1) to (GLY20) CRYSTAL STRUCTURE OF F114A MUTANT OF 3-DEOXY-D-MANNO-OCTULOSONATE 8- PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4jte:B (MET1) to (GLY20) CRYSTAL STRUCTURE OF F114A MUTANT OF 3-DEOXY-D-MANNO-OCTULOSONATE 8- PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4jte:C (MET1) to (GLY20) CRYSTAL STRUCTURE OF F114A MUTANT OF 3-DEOXY-D-MANNO-OCTULOSONATE 8- PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4jtg:A (MET1) to (GLY20) CRYSTAL STRUCTURE OF F114R/R117A MUTANT OF 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4jtg:B (MET1) to (GLY20) CRYSTAL STRUCTURE OF F114R/R117A MUTANT OF 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4jtg:D (MET1) to (GLY20) CRYSTAL STRUCTURE OF F114R/R117A MUTANT OF 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4jth:A (MET1) to (GLY20) CRYSTAL STRUCTURE OF F114R/R117Q MUTANT OF 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4jth:B (MET1) to (GLY20) CRYSTAL STRUCTURE OF F114R/R117Q MUTANT OF 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4jti:B (MET1) to (GLY20) CRYSTAL STRUCTURE OF F114R/R117Q/F139G MUTANT OF 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4jtj:B (MET1) to (GLY20) CRYSTAL STRUCTURE OF R117K MUTANT OF 3-DEOXY-D-MANNO-OCTULOSONATE 8- PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4jtk:D (MET1) to (GLY20) CRYSTAL STRUCTURE OF R117Q MUTANT OF 3-DEOXY-D-MANNO-OCTULOSONATE 8- PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3u6b:A (GLY257) to (ALA270) EF-TU (ESCHERICHIA COLI) IN COMPLEX WITH NVP-LDI028 | TRANSLATION FACTOR-ANTIBIOTIC COMPLEX
3hcg:B (HIS480) to (PRO505) STRUCTURE OF THE C-TERMINAL DOMAIN (MSRB) OF NEISSERIA MENINGITIDIS PILB (REDUCED FORM) | PILB, METHIONINE SULFOXIDE REDUCTASE B, REDUCED FORM, DISULFIDE BOND, ELECTRON TRANSPORT, MULTIFUNCTIONAL ENZYME, OXIDOREDUCTASE, REDOX- ACTIVE CENTER, TRANSPORT
3hcg:D (HIS480) to (PRO505) STRUCTURE OF THE C-TERMINAL DOMAIN (MSRB) OF NEISSERIA MENINGITIDIS PILB (REDUCED FORM) | PILB, METHIONINE SULFOXIDE REDUCTASE B, REDUCED FORM, DISULFIDE BOND, ELECTRON TRANSPORT, MULTIFUNCTIONAL ENZYME, OXIDOREDUCTASE, REDOX- ACTIVE CENTER, TRANSPORT
3hch:A (HIS480) to (PRO505) STRUCTURE OF THE C-TERMINAL DOMAIN (MSRB) OF NEISSERIA MENINGITIDIS PILB (COMPLEX WITH SUBSTRATE) | PILB, METHIONINE SULFOXIDE REDUCTASE B, COMPLEX WITH SUBSTRATE, DISULFIDE BOND, ELECTRON TRANSPORT, MULTIFUNCTIONAL ENZYME, OXIDOREDUCTASE, REDOX-ACTIVE CENTER, TRANSPORT
2eig:D (VAL1) to (TRP23) LOTUS TETRAGONOLOBUS SEED LECTIN (ISOFORM) | LOTUS TETRAGONOLOBUS, L-FUCOSYL, N-ACETYL-D-GLUCOSAMINE, SUGAR BINDING PROTEIN
3u9h:A (SER1124) to (ARG1159) COMPLEX STRUCTURE OF HUMAN TANKYRASE 2 WITH NICOTINAMIDE | PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, TRANSFERASE, ADP- RIBOSYLATION
2ejf:A (GLY45) to (SER67) CRYSTAL STRUCTURE OF THE BIOTIN PROTEIN LIGASE (MUTATIONS R48A AND K111A) AND BIOTIN CARBOXYL CARRIER PROTEIN COMPLEX FROM PYROCOCCUS HORIKOSHII OT3 | BIOTINYLATION, DIMER, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LIGASE
3ua7:B (ASP118) to (PRO140) CRYSTAL STRUCTURE OF THE HUMAN FYN SH3 DOMAIN IN COMPLEX WITH A PEPTIDE FROM THE HEPATITIS C VIRUS NS5A-PROTEIN | BETA BARREL, KINASE, POLY PROLINE RICH MOTIF, TRANSFERASE-VIRAL PROTEIN COMPLEX
4yoc:A (TYR924) to (PRO942) CRYSTAL STRUCTURE OF HUMAN DNMT1 AND USP7/HAUSP COMPLEX | DNA METHYLATION, DEUBIQUITINATION, DNA METHYLTRANSFERASE, MODIFICATION, TRANSFERASE-HYDROLASE COMPLEX
3hhq:I (LYS10) to (GLN37) CRYSTAL STRUCTURE OF APO DUT1P FROM SACCHAROMYCES CEREVISIAE | TRIMER, BETA BARREL, APO STRUCTURE, DUTP PYROPHOSPHATASE, SACCHAROMYCES CEREVISIAE, MOLECULAR REPLACEMENT, HYDROLASE, NUCLEOTIDE METABOLISM, PHOSPHOPROTEIN
1fkn:A (TYR342) to (PRO373) STRUCTURE OF BETA-SECRETASE COMPLEXED WITH INHIBITOR | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2, BASE, ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1fkn:B (TYR342) to (PRO373) STRUCTURE OF BETA-SECRETASE COMPLEXED WITH INHIBITOR | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2, BASE, ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3udh:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE WITH COMPOUND 1 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1r9g:B (PHE116) to (GLU141) THREE-DIMENSIONAL STRUCTURE OF YAAE FROM BACILLUS SUBTILIS | TRIAD AMIDOTRANSFERASE, GLUTAMINASE, ALPHA/BETA PROTEIN, COFACTOR BIOSYNTHESIS
4k3c:A (ILE755) to (PHE785) THE CRYSTAL STRUCTURE OF BAMA FROM HAEMOPHILUS DUCREYI LACKING POTRA DOMAINS 1-3 | BETA-BARREL MEMBRANE PROTEIN, INSERTASE, MEMBRANE PROTEIN
3hjp:A (GLU10) to (PRO38) THE CRYSTAL STRUCTURE OF BCP4 FROM SULFOLOBUS SOLFATARICUS | PEROXIREDOXIN, BACTERIOFERRITIN COMIGRATORY PROTEIN, OXIDOREDUCTASE
3hjp:C (GLU10) to (PRO38) THE CRYSTAL STRUCTURE OF BCP4 FROM SULFOLOBUS SOLFATARICUS | PEROXIREDOXIN, BACTERIOFERRITIN COMIGRATORY PROTEIN, OXIDOREDUCTASE
3hjp:D (GLU10) to (PRO38) THE CRYSTAL STRUCTURE OF BCP4 FROM SULFOLOBUS SOLFATARICUS | PEROXIREDOXIN, BACTERIOFERRITIN COMIGRATORY PROTEIN, OXIDOREDUCTASE
4k3x:C (GLY286) to (GLY319) CRYSTAL STRUCTURE OF A SUBTYPE H18 HEMAGGLUTININ HOMOLOGUE FROM A/FLAT-FACED BAT/PERU/033/2010 (H18N11) | INFLUENZA VIRUS, HEMAGGLUTININ HOMOLOGUE, H18, ECTODOMAIN, VIRAL PROTEIN
3uf4:A (ASP118) to (PRO140) CRYSTAL STRUCTURE OF A SH3 AND SH2 DOMAINS OF FYN PROTEIN (PROTO- CONCOGENE TYROSINE-PROTEIN KINASE FYN) FROM MUS MUSCULUS AT 1.98 A RESOLUTION | PHOSPHORYLATION, HOST-VIRUS INTERACTION, PROTEIN-TYROSINE KINASES, SRC HOMOLOGY DOMAINS, SRC-FAMILY KINASES, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, TRANSFERASE, PARTNERSHIP FOR T-CELL BIOLOGY
1fnz:A (GLY2) to (THR27) A BARK LECTIN FROM ROBINIA PSEUDOACACIA IN COMPLEX WITH N- ACETYLGALACTOSAMINE | JELLY ROLL, SUGAR BINDING PROTEIN
4k4f:B (SER1277) to (LYS1312) CO-CRYSTAL STRUCTURE OF TNKS1 WITH COMPOUND 18 [4-[(4S)-5,5-DIMETHYL- 2-OXO-4-PHENYL-1,3-OXAZOLIDIN-3-YL]-N-(QUINOLIN-8-YL)BENZAMIDE] | PARP, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2ewn:A (ALA114) to (GLU140) ECOLI BIOTIN REPRESSOR WITH CO-REPRESSOR ANALOG | HELIX-TURN-HELIX, DISORDER-TO-ORDER TRANSITION, BIOTIN, LIGASE, TRANSCRIPTION
2ewn:B (GLY115) to (GLU140) ECOLI BIOTIN REPRESSOR WITH CO-REPRESSOR ANALOG | HELIX-TURN-HELIX, DISORDER-TO-ORDER TRANSITION, BIOTIN, LIGASE, TRANSCRIPTION
2eyz:A (ASP142) to (ILE161) CT10-REGULATED KINASE ISOFORM II | SH2, SH3, SIGNALING PROTEIN
4k76:C (GLY300) to (GLY333) CFTR ASSOCIATED LIGAND (CAL) PDZ DOMAIN BOUND TO PEPTIDE ICAL36-TRL (ANSRWPTTRL) | PDZ DOMAIN, CAL, PIST, FIG, PDZ-PEPTIDE COMPLEX, CFTR ASSOCIATED LIGAND, CFTR, PEPTIDE BINDING PROTEIN-PROTEIN BINDING COMPLEX
4k8s:B (TYR342) to (PRO373) HYDROXYETHYLAMINE-BASED INHIBITORS OF BACE1: P1-P3 MACROCYCLIZATION CAN IMPROVE POTENCY, SELECTIVITY, AND CELL ACTIVITY | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2f1z:B (GLY326) to (SER353) CRYSTAL STRUCTURE OF HAUSP | HAUSP, USP7, UBP, DEUBIQUITINATING ENZYME, SUBSTRATE RECOGNITION, HYDROLASE
1rid:B (CYS1) to (GLU32) VACCINIA COMPLEMENT PROTEIN IN COMPLEX WITH HEPARIN | COMPLEMENT, REGULATION, SCR, IMMUNE SYSTEM
2va6:A (TYR342) to (PRO373) X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 24 | BASE, ZYMOGEN, PROTEASE, MEMBRANE, HYDROLASE, ALZHEIMER'S DISEASE, ALTERNATIVE SPLICING, MEMAPSIN 2, GLYCOPROTEIN, TRANSMEMBRANE, BETA-SECRETASE, ASPARTYL PROTEASE, ASPARTIC PROTEASE
4k9h:B (TYR342) to (PRO373) BACE-1 INHIBITOR COMPLEX | ASPARTIC PROTEASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ukn:A (SER664) to (GLY684) STRUCTURE OF THE C-LINKER/CNBHD OF ZELK CHANNELS IN C 2 2 21 SPACE GROUP | KCNH, ELK, ERG, EAG, CNBD, CNBHD, C-LINKER, ION CHANNEL, CYCLIC NUCLEOTIDE, CYCLIC NUCLEOTIDE-BINDING DOMAIN, ION TRANSPORT, TRANSPORT PROTEIN, MEMBRANE PROTEIN
1fv3:A (ASN972) to (SER989) THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH AN ANALOGUE OF ITS GANGLIOSIDE RECEPTOR GT1B | TOXIN, CARBOHYDRATE, GANGLIOSIDE, MULTI-VALENT BINDING, RECEPTOR
2f3e:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF THE BACE COMPLEX WITH AXQ093, A MACROCYCLIC INHIBITOR | BETA-SECRETASE, MEMAPSIN2, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, MACROCYCLIC PEPTIDOMIMETIC INHIBITOR, HYDROLASE
2f3e:C (TYR342) to (PRO373) CRYSTAL STRUCTURE OF THE BACE COMPLEX WITH AXQ093, A MACROCYCLIC INHIBITOR | BETA-SECRETASE, MEMAPSIN2, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, MACROCYCLIC PEPTIDOMIMETIC INHIBITOR, HYDROLASE
2f3f:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF THE BACE COMPLEX WITH BDF488, A MACROCYCLIC INHIBITOR | BETA-SECRETASE, MEMAPSIN2, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, MACROCYCLIC PEPTIDOMIMETIC INHIBITOR, HYDROLASE
2f4e:A (SER42) to (GLY61) N-TERMINAL DOMAIN OF FKBP42 FROM ARABIDOPSIS THALIANA | FKBP-LIKE, ALPHA-BETA, SIGNALING PROTEIN
1fwk:C (PHE150) to (ASN178) CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP | KINASE, TRANSFERASE
1fx5:A (ASP2) to (ILE27) CRYSTAL STRUCTURE ANALYSIS OF ULEX EUROPAEUS LECTIN I | LEGUME LECTIN, UE-I, HOMO-DIMER, FUCOSE SPECIFIC LECTIN, SUGAR BINDING PROTEIN
4yy7:A (GLY286) to (GLY319) THE STRUCTURE OF HEMAGGLUTININ FROM A H6N1 INFLUENZA VIRUS (A/CHICKEN/TAIWAN/A2837/2013) IN COMPLEX WITH AVIAN RECEPTOR ANALOG 3'SLNLN | HEMAGGLUTININ, IMMUNE SYSTEM
4yy7:C (GLY286) to (GLY319) THE STRUCTURE OF HEMAGGLUTININ FROM A H6N1 INFLUENZA VIRUS (A/CHICKEN/TAIWAN/A2837/2013) IN COMPLEX WITH AVIAN RECEPTOR ANALOG 3'SLNLN | HEMAGGLUTININ, IMMUNE SYSTEM
4z07:E (GLY161) to (GLY182) CO-CRYSTAL STRUCTURE OF THE TANDEM CNB (CNB-A/B) DOMAINS OF HUMAN PKG I BETA WITH CGMP | CGMP-BINDING DOMAINS, CGMP MEDIATED DIMERIC INTERFACE, ALLOSTERIC REGULATORY DOMAIN, SERINE-THREONINE KINASE, TRANSFERASE
4ke0:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH HYDROXYETHYLAMINE- MACROCYCLIC INHIBITOR 13 | ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, AMYLOID PRECURSOR PROTEIN (APP), HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ke0:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH HYDROXYETHYLAMINE- MACROCYCLIC INHIBITOR 13 | ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, AMYLOID PRECURSOR PROTEIN (APP), HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2fdp:C (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SECRETASE COMPLEXED WITH AN AMINO- ETHYLENE INHIBITOR | ASPARTYL PROTEASE, BACE, HYDROLASE
2vdf:A (ALA33) to (GLY84) STRUCTURE OF THE OPCA ADHESION FROM NEISSERIA MENINGITIDIS DETERMINED BY CRYSTALLIZATION FROM THE CUBIC MESOPHASE | INVASIN, ADHESIN, BETA BARREL, OUTER MEMBRANE, MEMBRANE PROTEIN
1g7v:A (MET1) to (MET25) CRYSTAL STRUCTURES OF KDO8P SYNTHASE IN ITS BINARY COMPLEXES WITH THE MECHANISM-BASED INHIBITOR | BETA-ALPHA-BARRELS, LYASE, LIPOPOLYSACCHARIDE
3uqr:C (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 WITH ITS INHIBITOR | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ur6:A (ALA48) to (GLU74) 1.5A RESOLUTION STRUCTURE OF APO NORWALK VIRUS PROTEASE | PROTEASE, NOROVIRUS, NORWALK VIRUS, ANTIVIRAL INHIBITORS, DIPEPTIDYL INHIBITOR, HYDROLASE
4z4h:A (LEU265) to (ARG287) HUMAN ARGONAUTE2 A481T MUTANT BOUND TO T1-A TARGET RNA | ARGONAUTE2, GENE REGULATION-RNA COMPLEX
2viy:A (TYR403) to (PRO434) HUMAN BACE-1 IN COMPLEX WITH N-((1S,2R)-3-(((1S)-2-( CYCLOHEXYLAMINO)-1-METHYL-2-OXOETHYL)AMINO)-2-HYDROXY-1-( PHENYLMETHYL)PROPYL)-3-(PENTYLSULFONYL)BENZAMIDE | ALTERNATIVE SPLICING, BETA-SITE APP CLEAVING ENZYME, BETA-SECRETASE, ASPARTYL PROTEASE, ASP-2, BACE-1, ZYMOGEN, PROTEASE, MEMBRANE, HYDROLASE, MEMAPSIN-2, GLYCOPROTEIN, TRANSMEMBRANE
2vj7:A (TYR403) to (PRO434) HUMAN BACE-1 IN COMPLEX WITH 3-(ETHYLAMINO)-N-((1S,2R)-2- HYDROXY-1-(PHENYLMETHYL)-3-(((3-(TRIFLUOROMETHYL)PHENYL) METHYL)AMINO)PROPYL)-5-(2-OXO-1-PYRROLIDINYL)BENZAMIDE | ALTERNATIVE SPLICING, BETA-SITE APP CLEAVING ENZYME, BETA-SECRETASE, ASPARTYL PROTEASE, ASP-2, BACE-1, ZYMOGEN, PROTEASE, MEMBRANE, HYDROLASE, MEMAPSIN-2, GLYCOPROTEIN, TRANSMEMBRANE
2vj9:A (TYR403) to (PRO434) HUMAN BACE-1 IN COMPLEX WITH N-((1S,2R)-3-(CYCLOHEXYLAMINO)- 2-HYDROXY-1-(PHENYLMETHYL)PROPYL)-3-(ETHYLAMINO)-5-(2-OXO- 1-PYRROLIDINYL)BENZAMIDE | ALTERNATIVE SPLICING, BETA-SITE APP CLEAVING ENZYME, BETA-SECRETASE, ASPARTYL PROTEASE, ASP-2, BACE-1, ZYMOGEN, PROTEASE, MEMBRANE, HYDROLASE, MEMAPSIN-2, GLYCOPROTEIN, TRANSMEMBRANE
4kl1:B (GLY638) to (GLY659) HCN4 CNBD IN COMPLEX WITH CGMP | CNBD, CAMP, CGMP, C-DI-GMP, C-DI-AMP, ION CHANNEL, HCN, POTASSIUM/SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL, CAMP BINDING, CGMP BINDING, PROTEIN TRANSPORT
4kl5:A (GLU54) to (MET75) CRYSTAL STRUCTURE OF NPUDNAE INTEIN | HINT, INTEIN, NPUDNAE INTEN, UNKNOWN FUNCTION
3hs0:C (ARG1508) to (THR1530) COBRA VENOM FACTOR (CVF) IN COMPLEX WITH HUMAN FACTOR B | SERINE PROTEASE, GLYCOSILATED, MULTI-DOMAIN, COMPLEMENT SYSTEM, CONVERTASE, COMPLEMENT ALTERNATE PATHWAY, COMPLEMENT PATHWAY, DISULFIDE BOND, GLYCOPROTEIN, IMMUNE RESPONSE, INFLAMMATORY RESPONSE, INNATE IMMUNITY, SECRETED, THIOESTER BOND, CLEAVAGE ON PAIR OF BASIC RESIDUES, GLYCATION, HYDROLASE, PROTEASE, SUSHI, ZYMOGEN, IMMUNE SYSTEM
4kmu:H (ARG528) to (THR581) X-RAY CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH RIFAMPIN | TRANSCRIPTION, DNA, RNA, TRANSFERASE-ANTIBIOTIC COMPLEX
2fpe:G (TYR35) to (GLU57) CONSERVED DIMERIZATION OF THE IB1 SRC-HOMOLOGY 3 DOMAIN | SRC-HOMOLOGY 3 (SH3) DOMAIN, ALL BETA STRUCTURE, SIGNALING PROTEIN
2fpe:H (TYR35) to (LYS60) CONSERVED DIMERIZATION OF THE IB1 SRC-HOMOLOGY 3 DOMAIN | SRC-HOMOLOGY 3 (SH3) DOMAIN, ALL BETA STRUCTURE, SIGNALING PROTEIN
3hvg:B (TYR342) to (PRO373) STRUCTURE OF BACE (BETA SECRETASE) IN COMPLEX WITH EV0 | PROTEASE, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, AMYLOID PRECURSOR PROTEIN SECRETASES, ASPARTIC ENDOPEPTIDASES, FRAGMENT- BASED DRUG DESIGN, FLUORESCENCE POLARISATION, DISULFIDE BOND, TRANSMEMBRANE, ZYMOGEN
4ze9:A (PRO485) to (GLY521) SE-PBP ACCA FROM A. TUMEFACIENS C58 IN COMPLEX WITH AGROCINOPINE A | PBP FROM CLASS C, TRANSPORT PROTEIN
2fvk:A (ARG493) to (LYS510) CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINASE FROM SACCHAROMYCES KLUYVERI IN COMPLEX WITH THE SUBSTRATE DIHYDROURACIL | BETA/ALPHA BARREL, BETA SANDWICH, HYDROLASE
2fvk:C (ARG493) to (LYS510) CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINASE FROM SACCHAROMYCES KLUYVERI IN COMPLEX WITH THE SUBSTRATE DIHYDROURACIL | BETA/ALPHA BARREL, BETA SANDWICH, HYDROLASE
2fvk:D (ARG493) to (LYS510) CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINASE FROM SACCHAROMYCES KLUYVERI IN COMPLEX WITH THE SUBSTRATE DIHYDROURACIL | BETA/ALPHA BARREL, BETA SANDWICH, HYDROLASE
2fvm:A (ARG493) to (LYS510) CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINASE FROM SACCHAROMYCES KLUYVERI IN COMPLEX WITH THE REACTION PRODUCT N-CARBAMYL-BETA-ALANINE | BETA/ALPHA BARREL, BETA SANDWICH, HYDROLASE
2fvm:B (ARG493) to (LYS510) CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINASE FROM SACCHAROMYCES KLUYVERI IN COMPLEX WITH THE REACTION PRODUCT N-CARBAMYL-BETA-ALANINE | BETA/ALPHA BARREL, BETA SANDWICH, HYDROLASE
2fvm:C (ARG493) to (LYS510) CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINASE FROM SACCHAROMYCES KLUYVERI IN COMPLEX WITH THE REACTION PRODUCT N-CARBAMYL-BETA-ALANINE | BETA/ALPHA BARREL, BETA SANDWICH, HYDROLASE
2fvm:D (ARG493) to (LYS510) CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINASE FROM SACCHAROMYCES KLUYVERI IN COMPLEX WITH THE REACTION PRODUCT N-CARBAMYL-BETA-ALANINE | BETA/ALPHA BARREL, BETA SANDWICH, HYDROLASE
1sf0:A (ALA41) to (ASP56) BACKBONE SOLUTION STRUCTURE OF MIXED ALPHA/BETA PROTEIN PF1061 | RESIDUAL DIPOLAR COUPLINGS, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, SOUTHEAST COLLABORATORY FOR STRUCTURAL GENOMICS, SECSG, UNKNOWN FUNCTION
3hyx:F (ASN86) to (ILE103) 3-D X-RAY STRUCTURE OF THE SULFIDE:QUINONE OXIDOREDUCTASE FROM AQUIFEX AEOLICUS IN COMPLEX WITH AURACHIN C | MONOTOPIC MEMBRANE PROTEIN, SULFIDE OXIDATION, ROSSMANN-FOLD DOMAIN, FLAVOPROTEIN, QUINONE REDUCTION, OXIDOREDUCTASE
1gml:A (GLY348) to (GLY378) CRYSTAL STRUCTURE OF THE MOUSE CCT GAMMA APICAL DOMAIN (TRICLINIC) | CHAPERONE, CHAPERONIN, ACTIN, TUBULIN
1gml:B (GLY348) to (GLY378) CRYSTAL STRUCTURE OF THE MOUSE CCT GAMMA APICAL DOMAIN (TRICLINIC) | CHAPERONE, CHAPERONIN, ACTIN, TUBULIN
2fyq:A (ALA48) to (GLU75) CRYSTAL STRUCTURE OF THE NORWALK VIRUS PROTEASE | PROTEASE, NOROVIRUS, NORWALK VIRUS, CALICIVIRUS, VIRAL PROTEIN
2fyr:A (ALA48) to (GLU75) CRYSTAL STRUCTURE OF NORWALK VIRUS PROTEASE GROWN IN THE PRESENCE OF AEBSF | PROTEASE, NOROVIRUS, NORWALK VIRUS, CALICIVIRUS, VIRAL PROTEIN
2vnn:A (TYR403) to (PRO434) HUMAN BACE-1 IN COMPLEX WITH 7-ETHYL-N-((1S,2R)-2-HYDROXY-1- (PHENYLMETHYL)-3-(((3-(TRIFLUOROMETHYL)PHENYL)METHYL)AMINO) PROPYL)-1-METHYL-3,4-DIHYDRO-1H-(1,2,5)THIADIAZEPINO(3,4,5- HI)INDOLE-9-CARBOXAMIDE 2,2-DIOXIDE | HYDROLASE, ALTERNATIVE SPLICING, BETA-SITE APP CLEAVING ENZYME, BETA-SECRETASE, ASPARTYL PROTEASE, ASP-2, BACE-1, ZYMOGEN, PROTEASE, MEMBRANE, MEMAPSIN-2, GLYCOPROTEIN, TRANSMEMBRANE
4zgx:G (SER388) to (PHE406) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
4zgx:J (SER388) to (PHE406) STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH (+)-(R)-N- (4-(4-CHLORO-3-FLUOROPHENYL)-5,6,7,8-TETRAHYDROISOQUINOLIN-8-YL) PROPIONAMIDE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, OXIDOREDUCTASE
3v7c:A (GLY119) to (ARG142) CYSTAL STRUCTURE OF SABPL IN COMPLEX WITH INHIBITOR | BIOTIN, METABOLISM, BIOTIN CARBOXYL CARRIER PROTEIN, LIGASE-LIGASE INHIBITOR COMPLEX
2vob:A (LYS88) to (ALA114) TRYPANOTHIONE SYNTHETASE | LIGASE
4kr4:A (GLY132) to (ASP171) SALMONELLA TYPHI OMPF COMPLEX WITH AMPICILLIN | BETA BARREL, TRANSPORT, OUTER MEMBRANE, MEMBRANE PROTEIN
4kr4:B (THR136) to (ASP171) SALMONELLA TYPHI OMPF COMPLEX WITH AMPICILLIN | BETA BARREL, TRANSPORT, OUTER MEMBRANE, MEMBRANE PROTEIN
4kr8:A (GLY133) to (ASP171) SALMONELLA TYPHI OMPF COMPLEX WITH DAUNOMYCIN | BETA BARREL, TRANSPORT, OUTER MEMBRANE, MEMBRANE PROTEIN
4kra:B (MET1) to (ASP33) SALMONELLA TYPHI OMPF COMPLEX WITH CIPROFLOXACIN | BETA BARREL, TRANSPORT, OUTER MEMBRANE, MEMBRANE PROTEIN
2vpm:B (LYS88) to (ALA114) TRYPANOTHIONE SYNTHETASE | LIGASE
2vps:A (LYS88) to (ALA114) STRUCTURE OF THE BIFUNCTIONAL LEISHMANIA MAJOR TRYPANOTHIONE SYNTHETASE-AMIDASE | LIGASE
4krt:A (PHE286) to (ASP312) X-RAY STRUCTURE OF ENDOLYSIN FROM CLOSTRIDIUM PERFRINGENS PHAGE PHISM101 | BETA/ALPHA BARREL, MURAMIDASE AND PUTATIVE CELL-WALL BINDING, HYDROLASE
2g2u:B (SER108) to (SER139) CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) COMPLEX | BETA-LACTAMASE, BETA-LACTAMASE INHIBITOR, PROTEIN-PROTEIN COMPLEX, BLIP, SHV-1, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3v8u:A (GLU524) to (ASN566) THE CRYSTAL STRUCTURE OF TRANSFERRIN BINDING PROTEIN B (TBPB) FROM NEISSERIA MENINGITIDIS SEROGROUP B | TRANSFERRIN BINDING PROTEIN, LIPOPROTEIN, TRANSPORT PROTEIN
3v8u:B (VAL523) to (ASN566) THE CRYSTAL STRUCTURE OF TRANSFERRIN BINDING PROTEIN B (TBPB) FROM NEISSERIA MENINGITIDIS SEROGROUP B | TRANSFERRIN BINDING PROTEIN, LIPOPROTEIN, TRANSPORT PROTEIN
1gqn:A (MET1) to (ARG25) NATIVE 3-DEHYDROQUINASE FROM SALMONELLA TYPHI | LYASE, 3-DEHYDROQUINATE DEHYDRATASE, SHIKIMATE PATHWAY, A/B BARREL
2vr2:A (LEU438) to (ALA457) HUMAN DIHYDROPYRIMIDINASE | HYDANTOINASE, METAL-BINDING, DISEASE MUTATION, DIHYDROPYRIMIDINE AMIDOHYDROLASE, DIHYDROPYRIMIDINASE, NUCLEOTIDE METABOLISM, DHP, DPYS, DHPASE, HYDROLASE, ZN-BINDING
2vr5:A (GLY677) to (GLU706) CRYSTAL STRUCTURE OF TREX FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH ACARBOSE INTERMEDIATE AND GLUCOSE | HYDROLASE, GLYCOSIDASE, GLYCOSYL HYDROLASE
1soz:A (SER174) to (HIS198) CRYSTAL STRUCTURE OF DEGS PROTEASE IN COMPLEX WITH AN ACTIVATING PEPTIDE | STRESS RESPONSE, PROTEIN QUALITY CONTROL, PDZ, UPR, HTRA, HYDROLASE
2g94:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SECRETASE BOUND TO A POTENT AND HIGHLY SELECTIVE INHIBITOR. | BETA SECRETASE, ALZHEIMER'S DISEASE, MEMAPSIN, BACE, ASP2, ASPARTIC PROTEASE, DRUG DESIGN, PROTEASE INHIBITOR, HYDROLASE
2g94:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SECRETASE BOUND TO A POTENT AND HIGHLY SELECTIVE INHIBITOR. | BETA SECRETASE, ALZHEIMER'S DISEASE, MEMAPSIN, BACE, ASP2, ASPARTIC PROTEASE, DRUG DESIGN, PROTEASE INHIBITOR, HYDROLASE
2g94:C (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SECRETASE BOUND TO A POTENT AND HIGHLY SELECTIVE INHIBITOR. | BETA SECRETASE, ALZHEIMER'S DISEASE, MEMAPSIN, BACE, ASP2, ASPARTIC PROTEASE, DRUG DESIGN, PROTEASE INHIBITOR, HYDROLASE
2g94:D (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SECRETASE BOUND TO A POTENT AND HIGHLY SELECTIVE INHIBITOR. | BETA SECRETASE, ALZHEIMER'S DISEASE, MEMAPSIN, BACE, ASP2, ASPARTIC PROTEASE, DRUG DESIGN, PROTEASE INHIBITOR, HYDROLASE
2vw1:A (ASP184) to (GLY203) CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE | HYDROLASE, SIALIDASE, NEURAMINIDASE, VIRULENCE FACTOR, DRUG DESIGN
1suo:A (ASP374) to (VAL391) STRUCTURE OF MAMMALIAN CYTOCHROME P450 2B4 WITH BOUND 4-(4- CHLOROPHENYL)IMIDAZOLE | OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2, CYTOCHROME P450, MONOOXYGENASE
4kxt:A (THR173) to (LEU190) STRUCTURE OF HUMAN ARGONAUTE1 IN COMPLEX WITH GUIDE RNA | RNASE H FOLD, NUCLEASE, RNA, HYDROLASE-RNA COMPLEX
2gev:A (ALA174) to (GLU201) PANTOTHENATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS (MTPANK) IN COMPLEX WITH A COENZYME A DERIVATIVE, FORM-II (LT) | HOMODIMER, COA BIOSYNTHESIS, NUCLEOTIDE BINDING, TRANSFERASE
2vz7:A (GLU300) to (VAL318) CRYSTAL STRUCTURE OF THE YC-17-BOUND PIKC D50N MUTANT | OXIDOREDUCTASE, ANTIBIOTIC BIOSYNTHESIS, PIKC, IRON, HEME, CYP107L1, MONOOXYGENASE, MACROLIDE MONOOXYGENASE, METAL-BINDING, CYTOCHROME P450
2vz7:B (PRO301) to (VAL317) CRYSTAL STRUCTURE OF THE YC-17-BOUND PIKC D50N MUTANT | OXIDOREDUCTASE, ANTIBIOTIC BIOSYNTHESIS, PIKC, IRON, HEME, CYP107L1, MONOOXYGENASE, MACROLIDE MONOOXYGENASE, METAL-BINDING, CYTOCHROME P450
4l1m:B (GLY576) to (VAL597) STRUCTURE OF THE FIRST RCC1-LIKE DOMAIN OF HERC2 | RCC1, RLD, BETA-PROPELLER, HERC2, STRUCTURAL GENOMICS CONSORTIUM, SGC, LIGASE
4l1u:C (GLY384) to (GLU410) CRYSTAL STRUCTURE OF HUMAN RTF1 PLUS3 DOMAIN IN COMPLEX WITH SPT5 CTR PHOSPHOPEPTIDE | TUTOR, PLUS3, PEPTIDE BINDING PROTEIN, SPT5 CTR BINDING, TRANSCRIPTION, PAF1 COMPLEX, RTF1, ORF ASSOCIATION REGION, CHROMATIN, TRANSCRIPTION-PEPTIDE COMPLEX
3vk7:A (ALA98) to (PHE121) CRYSTAL STRUCTURE OF DNA-GLYCOSYLASE BOUND TO DNA CONTAINING 5- HYDROXYURACIL | DNA GLYCOSYLASE, HNEIL1 ORTHOLOG, DNA LESION, 5-HYDROXYURACIL, ZINCLESS FINGER, DNA BINDING, HYDROLASE-DNA COMPLEX
3vk7:B (ALA98) to (PHE121) CRYSTAL STRUCTURE OF DNA-GLYCOSYLASE BOUND TO DNA CONTAINING 5- HYDROXYURACIL | DNA GLYCOSYLASE, HNEIL1 ORTHOLOG, DNA LESION, 5-HYDROXYURACIL, ZINCLESS FINGER, DNA BINDING, HYDROLASE-DNA COMPLEX
3ibr:A (ALA28) to (PRO55) CRYSTAL STRUCTURE OF P. AERUGINOSA BACTERIOPHYTOCHROME PHOTOSENSORY CORE MODULE MUTANT Q188L IN THE MIXED PR/PFR STATE | PHYTOCHROME, RED-LIGHT PHOTORECEPTOR, PHOTOCONVERSION, CHROMOPHORE, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PHOTORECEPTOR PROTEIN, RECEPTOR, SENSORY TRANSDUCTION, TRANSFERASE
3vk8:A (ALA98) to (PHE121) CRYSTAL STRUCTURE OF DNA-GLYCOSYLASE BOUND TO DNA CONTAINING THYMINE GLYCOL | DNA GLYCOSYLASE, HNEIL1 ORTHOLOG, DNA LESION, THYMINE GLYCOL, ZINCLESS FINGER, DNA BINDING, HYDROLASE-DNA COMPLEX
3ic8:B (GLU283) to (LYS309) THE CRYSTAL STRUCTURE OF A GST-LIKE PROTEIN FROM PSEUDOMONAS SYRINGAE TO 2.4A | GLUTATHIONE, TRANSFERASE, PSEUDOMONAS, SYRINGAE, PSI, MCSG, STRUCTURAL GENOMICS, MIDWEST CENTER FOR STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, UNKNOWN FUNCTION
2vzm:A (GLU300) to (LEU319) CRYSTAL STRUCTURE OF THE NARBOMYCIN-BOUND PIKC D50N MUTANT | OXIDOREDUCTASE, PIKC, IRON, HEME, CYP107L1, MONOOXYGENASE, ANTIBIOTIC BIOSYNTHESIS, MACROLIDE MONOOXYGENASE, METAL-BINDING, CYTOCHROME P450
2vzm:B (GLU300) to (LEU319) CRYSTAL STRUCTURE OF THE NARBOMYCIN-BOUND PIKC D50N MUTANT | OXIDOREDUCTASE, PIKC, IRON, HEME, CYP107L1, MONOOXYGENASE, ANTIBIOTIC BIOSYNTHESIS, MACROLIDE MONOOXYGENASE, METAL-BINDING, CYTOCHROME P450
1h72:C (PHE150) to (ASN178) CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH HSE | TRANSFERASE, KINASE, THREONINE BIOSYNTHESIS
4l92:A (ALA199) to (THR221) STRUCTURE OF THE RBP FROM LACTOCOCCAL PHAGE 1358 IN COMPLEX WITH 2 GLCNAC MOLECULES | BETA SANDWICH DOMAIN, PHAGE RECEPTOR BINDING PROTEIN, LACTOCOCCUS LACTIS PELLICLE SACCHARIDE, VIRAL PROTEIN
4l92:B (ALA199) to (THR221) STRUCTURE OF THE RBP FROM LACTOCOCCAL PHAGE 1358 IN COMPLEX WITH 2 GLCNAC MOLECULES | BETA SANDWICH DOMAIN, PHAGE RECEPTOR BINDING PROTEIN, LACTOCOCCUS LACTIS PELLICLE SACCHARIDE, VIRAL PROTEIN
4l97:A (ALA199) to (THR221) STRUCTURE OF THE RBP OF LACTOCOCCAL PHAGE 1358 IN COMPLEX WITH GLUCOSE-1-PHOSPHATE | BETA SANDWICH DOMAIN, PHAGE RECEPTOR BINDING PROTEIN, LACTOCOCCUS LACTIS PELLICLE SACCHARIDES CELL WALL, VIRAL PROTEIN
4l97:B (ALA199) to (THR221) STRUCTURE OF THE RBP OF LACTOCOCCAL PHAGE 1358 IN COMPLEX WITH GLUCOSE-1-PHOSPHATE | BETA SANDWICH DOMAIN, PHAGE RECEPTOR BINDING PROTEIN, LACTOCOCCUS LACTIS PELLICLE SACCHARIDES CELL WALL, VIRAL PROTEIN
4zsm:B (TYR342) to (PRO373) BACE CRYSTAL STRUCTURE WITH BICYCLIC AMINOTHIAZINE FRAGMENT | ASPARTYL, PROTEASE, BETA-SECRETASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4zsp:A (TYR342) to (PRO373) BACE CRYSTAL STRUCTURE WITH BICYCLIC AMINOTHIAZINE INHIBITOR | ASPARTYL, PROTEASE, BETA-SECRETASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4zsp:B (TYR342) to (PRO373) BACE CRYSTAL STRUCTURE WITH BICYCLIC AMINOTHIAZINE INHIBITOR | ASPARTYL, PROTEASE, BETA-SECRETASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4zsq:A (TYR342) to (PRO373) BACE CRYSTAL STRUCTURE WITH TRICYCLIC AMINOTHIAZINE INHIBITOR | ASPARTYL, PROTEASE, BETA-SECRETASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4zsq:B (TYR342) to (PRO373) BACE CRYSTAL STRUCTURE WITH TRICYCLIC AMINOTHIAZINE INHIBITOR | ASPARTYL, PROTEASE, BETA-SECRETASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4zsr:A (TYR342) to (PRO373) BACE CRYSTAL STRUCTURE WITH TRICYCLIC AMINOTHIAZINE INHIBITOR | ASPARTYL, PROTEASE, BETA-SECRETASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4zsr:B (TYR342) to (PRO373) BACE CRYSTAL STRUCTURE WITH TRICYCLIC AMINOTHIAZINE INHIBITOR | ASPARTYL, PROTEASE, BETA-SECRETASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2w5o:A (GLN101) to (ILE135) COMPLEX STRUCTURE OF THE GH93 ALPHA-L-ARABINOFURANOSIDASE OF FUSARIUM GRAMINEARUM WITH ARABINOBIOSE | HYDROLASE, ALPHA-L-ARABINOFURANOSIDASE, GLYCOSYL HYDROLASE, GH93, ARABINOBIOSE
1tcz:A (ALA29) to (PHE74) CRYSTAL STRUCTURE OF A TRUNCATED VERSION OF THE PHAGE LAMDA PROTEIN GPD | PHAGE LAMDA PROTEIN GPD, VIRAL PROTEIN
1tcz:B (ALA229) to (PHE274) CRYSTAL STRUCTURE OF A TRUNCATED VERSION OF THE PHAGE LAMDA PROTEIN GPD | PHAGE LAMDA PROTEIN GPD, VIRAL PROTEIN
1tcz:C (ALA429) to (TYR475) CRYSTAL STRUCTURE OF A TRUNCATED VERSION OF THE PHAGE LAMDA PROTEIN GPD | PHAGE LAMDA PROTEIN GPD, VIRAL PROTEIN
1tcz:D (ALA629) to (PHE674) CRYSTAL STRUCTURE OF A TRUNCATED VERSION OF THE PHAGE LAMDA PROTEIN GPD | PHAGE LAMDA PROTEIN GPD, VIRAL PROTEIN
1tcz:E (ALA829) to (PHE874) CRYSTAL STRUCTURE OF A TRUNCATED VERSION OF THE PHAGE LAMDA PROTEIN GPD | PHAGE LAMDA PROTEIN GPD, VIRAL PROTEIN
1tcz:F (ALA1029) to (TYR1075) CRYSTAL STRUCTURE OF A TRUNCATED VERSION OF THE PHAGE LAMDA PROTEIN GPD | PHAGE LAMDA PROTEIN GPD, VIRAL PROTEIN
4ldu:A (PRO194) to (HIS221) CRYSTAL STRUCTURE OF THE DNA BINDING DOMAIN OF ARABIDOPSIS THALIANA AUXIN RESPONSE FACTOR 5 | TRANSCRIPTION FACTOR, DNA BINDING PROTEIN, NUCLEUS
1td3:A (SER32) to (SER80) CRYSTAL STRUCTURE OF VSHP_BPP21 IN SPACE GROUP C2 | SHP, VIRAL PROTEIN
1td3:B (SER232) to (SER280) CRYSTAL STRUCTURE OF VSHP_BPP21 IN SPACE GROUP C2 | SHP, VIRAL PROTEIN
1td3:C (SER432) to (SER480) CRYSTAL STRUCTURE OF VSHP_BPP21 IN SPACE GROUP C2 | SHP, VIRAL PROTEIN
4le9:A (GLY116) to (PRO139) CRYSTAL STRUCTURE OF A CHIMERIC C-SRC-SH3 DOMAIN | BETA SHANDWICH, SH3, KINASE, PROLY PROLINE RICH MOTIFS, PHOSPHORYLATION, TRANSFERASE
4lef:C (GLY7) to (LEU19) CRYSTAL STRUCTURE OF PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI COMPLEXED WITH PHOSPHATE IN ACTIVE SITE | PHP FOLD, HYDROLASE
4lef:D (GLY7) to (LEU19) CRYSTAL STRUCTURE OF PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI COMPLEXED WITH PHOSPHATE IN ACTIVE SITE | PHP FOLD, HYDROLASE
4lef:A (TYR8) to (LEU19) CRYSTAL STRUCTURE OF PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI COMPLEXED WITH PHOSPHATE IN ACTIVE SITE | PHP FOLD, HYDROLASE
4lef:B (GLY7) to (LEU19) CRYSTAL STRUCTURE OF PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI COMPLEXED WITH PHOSPHATE IN ACTIVE SITE | PHP FOLD, HYDROLASE
4lef:E (GLY7) to (LEU19) CRYSTAL STRUCTURE OF PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI COMPLEXED WITH PHOSPHATE IN ACTIVE SITE | PHP FOLD, HYDROLASE
4lef:F (GLY7) to (LEU19) CRYSTAL STRUCTURE OF PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI COMPLEXED WITH PHOSPHATE IN ACTIVE SITE | PHP FOLD, HYDROLASE
4lef:G (TYR8) to (LEU19) CRYSTAL STRUCTURE OF PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI COMPLEXED WITH PHOSPHATE IN ACTIVE SITE | PHP FOLD, HYDROLASE
1hbp:A (ASN40) to (CYS70) CRYSTAL STRUCTURE OF LIGANDED AND UNLIGANDED FORMS OF BOVINE PLASMA RETINOL-BINDING PROTEIN | RETINOL TRANSPORT
3ine:A (TYR404) to (PRO435) BACE1 WITH THE AMINOHYDANTOIN COMPOUND S-34 | BACE1, XRAY, INHIBITOR, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3inf:A (TYR404) to (PRO435) BACE1 WITH THE AMINOHYDANTOIN COMPOUND 37 | BACE1, INHIBITOR, XRAY, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
1hcc:A (GLU1) to (LYS32) THREE-DIMENSIONAL STRUCTURE OF A COMPLEMENT CONTROL PROTEIN MODULE IN SOLUTION | GLYCOPROTEIN
2w8h:A (LYS172) to (THR193) CRYSTAL STRUCTURE OF SPIN LABELED WZA24-345. | LIPOPROTEIN, MEMBRANE PROTEIN
2w8h:E (LYS172) to (THR193) CRYSTAL STRUCTURE OF SPIN LABELED WZA24-345. | LIPOPROTEIN, MEMBRANE PROTEIN
4zv4:B (GLY261) to (ALA274) STRUCTURE OF TSE6 IN COMPLEX WITH EF-TU | T6SS EFFECTOR, TRANSLATION ELONGATION FACTOR, TRANSLATION
1hgw:B (GLY355) to (LYS395) CEL6A D175A MUTANT | HYDROLASE (O-GLYCOSYL), GLYCOSIDASE, GLYCOPROTEIN
1hgy:A (GLY355) to (LYS395) CEL6A D221A MUTANT | HYDROLASE (O-GLYCOSYL), GLYCOSIDASE, GLYCOPROTEIN
1hgy:B (GLY355) to (LYS395) CEL6A D221A MUTANT | HYDROLASE (O-GLYCOSYL), GLYCOSIDASE, GLYCOPROTEIN
1hm2:A (GLY495) to (PHE512) ACTIVE SITE OF CHONDROITINASE AC LYASE REVEALED BY THE STRUCTURE OF ENZYME-OLIGOSACCHARIDE COMPLEXES AND MUTAGENESIS | PROTEIN-OLIGOSACCHARIDE COMPLEX, ACTIVE SITE, CATALYSIS, LYASE
4ljz:J (LEU1078) to (LEU1109) CRYSTAL STRUCTURE ANALYSIS OF THE E.COLI HOLOENZYME | DNA DIRECTED RNA POLYMERASE, TRANSFERASE
1hmy:A (GLY230) to (THR250) CRYSTAL STRUCTURE OF THE HHAI DNA METHYLTRANSFERASE COMPLEXED WITH S- ADENOSYL-L-METHIONINE | TRANSFERASE(METHYLTRANSFERASE)
3ivh:A (TYR403) to (PRO434) DESIGN AND SYNTHESIS OF POTENT BACE-1 INHIBITORS WITH CELLULAR ACTIVITY: STRUCTURE-ACTIVITY RELATIONSHIP OF P1 SUBSTITUENTS | ASPARTYL PROTEASE, BACE-1 INHIBITORS, ALZHEIMER'S DISEASE, STRUCTURE- BASED DRUG DESIGN, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
1tr7:B (PHE1) to (ASN23) FIMH ADHESIN RECEPTOR BINDING DOMAIN FROM UROPATHOGENIC E. COLI | TYPE-1 PILI, ADHESION, URINARY TRACT INFECTIONS, UROPATHOGENIC E. COLI, CARBOHYDRATE BINDING, CELL ADHESION
1tr7:A (PHE1) to (SER17) FIMH ADHESIN RECEPTOR BINDING DOMAIN FROM UROPATHOGENIC E. COLI | TYPE-1 PILI, ADHESION, URINARY TRACT INFECTIONS, UROPATHOGENIC E. COLI, CARBOHYDRATE BINDING, CELL ADHESION
3iwz:C (GLY61) to (GLY87) THE C-DI-GMP RESPONSIVE GLOBAL REGULATOR CLP LINKS CELL-CELL SIGNALING TO VIRULENCE GENE EXPRESSION IN XANTHOMONAS CAMPESTRIS | XCC, PATHOGENICITY, CRP, CLP, C-DI-GMP RECEPTOR, QUORUM SENSING, DNA- BINDING, TRANSCRIPTION, TRANSCRIPTION REGULATION
2wez:A (TYR403) to (PRO434) HUMAN BACE-1 IN COMPLEX WITH 1-ETHYL-N-((1S,2R)-2-HYDROXY-3- (((3-(METHYLOXY)PHENYL)METHYL)AMINO)-1-(PHENYLMETHYL) PROPYL)-4-(2-OXO-1-PYRROLIDINYL)-1H-INDOLE-6-CARBOXAMIDE | HYDROLASE, MEMAPSIN-2, POLYMORPHISM, GLYCOPROTEIN, ASP-2, BACE-1, ZYMOGEN, PROTEASE, MEMBRANE, TRANSMEMBRANE, BETA-SECRETASE, DISULFIDE BOND, ASPARTYL PROTEASE, ALTERNATIVE SPLICING, BETA-SITE APP CLEAVING ENZYME
2wf0:A (TYR403) to (PRO434) HUMAN BACE-1 IN COMPLEX WITH 4-ETHYL-N-((1S,2R)-2-HYDROXY-1- (PHENYLMETHYL)-3-(((3-(TRIFLUOROMETHYL)PHENYL)METHYL)AMINO) PROPYL)-8-(2-OXO-1-PYRROLIDINYL)-6-QUINOLINECARBOXAMIDE | HYDROLASE, MEMAPSIN-2, POLYMORPHISM, GLYCOPROTEIN, ASP-2, BACE-1, ZYMOGEN, PROTEASE, MEMBRANE, TRANSMEMBRANE, BETA-SECRETASE, DISULFIDE BOND, ASPARTYL PROTEASE, ALTERNATIVE SPLICING, BETA-SITE APP CLEAVING ENZYME
2hfs:B (LEU164) to (GLY193) CRYSTAL STRUCTURE OF L. MAJOR MEVALONATE KINASE | GHMP KINASE, MEVALONATE KINASE, TRYPANOSOMATID PARASITE, TRANSFERASE
2wf1:A (TYR403) to (PRO434) HUMAN BACE-1 IN COMPLEX WITH 7-ETHYL-N-((1S,2R)-2-HYDROXY-3- (((3-(METHYLOXY)PHENYL(METHYL)AMINO)-1-(PHENYLMETHYL) PROPYL)-1-METHYL-3,4-DIHYDRO-1H-(1,2,5)THIADIAZEPINO(3,4,5- HI)INDOLE-9-CARBOXAMIDE 2,2-DIOXIDE | HYDROLASE, MEMAPSIN-2, POLYMORPHISM, GLYCOPROTEIN, ASP-2, BACE-1, ZYMOGEN, PROTEASE, MEMBRANE, TRANSMEMBRANE, BETA-SECRETASE, DISULFIDE BOND, ASPARTYL PROTEASE, ALTERNATIVE SPLICING, BETA-SITE APP CLEAVING ENZYME
3ixj:C (TYR390) to (PRO421) CRYSTAL STRUCTURE OF BETA-SECRETASE 1 IN COMPLEX WITH SELECTIVE BETA-SECRETASE 1 INHIBITOR | BACE, BETA SECRETASE-1, INHIBITOR, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN, DISULFIDE BOND, POLYMORPHISM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2wf2:A (TYR403) to (PRO434) HUMAN BACE-1 IN COMPLEX WITH 8-ETHYL-N-((1S,2R)-2-HYDROXY-3- (((3-(METHYLOXY)PHENYL)METHYL)AMINO)-1-(PHENYLMETHYL) PROPYL)-1-METHYL-3,4,7,8-TETRAHYDRO-1H,6H-(1,2,5) THIADIAZEPINO(5,4,3-DE)QUINOXALINE-10-CARBOXAMIDE 2,2- DIOXIDE | HYDROLASE, MEMAPSIN-2, POLYMORPHISM, GLYCOPROTEIN, ASP-2, BACE-1, ZYMOGEN, PROTEASE, MEMBRANE, TRANSMEMBRANE, BETA-SECRETASE, DISULFIDE BOND, ASPARTYL PROTEASE, ALTERNATIVE SPLICING, BETA-SITE APP CLEAVING ENZYME
2wf3:A (TYR403) to (PRO434) HUMAN BACE-1 IN COMPLEX WITH 6-(ETHYLAMINO)-N-((1S,2R)-2- HYDROXY-3-(((3-(METHYLOXY)PHENYL)METHYL)AMINO)-1-( PHENYLMETHYL)PROPYL)-1-METHYL-1,3,4,5-TETRAHYDRO-2,1- BENZOTHIAZEPINE-8-CARBOXAMIDE 2,2-DIOXIDE | HYDROLASE, MEMAPSIN-2, POLYMORPHISM, GLYCOPROTEIN, ASP-2, BACE-1, ZYMOGEN, PROTEASE, MEMBRANE, TRANSMEMBRANE, BETA-SECRETASE, DISULFIDE BOND, ASPARTYL PROTEASE, ALTERNATIVE SPLICING, BETA-SITE APP CLEAVING ENZYME
2wf4:A (TYR403) to (PRO434) HUMAN BACE-1 IN COMPLEX WITH 6-ETHYL-1-METHYL-N-((1S)-2-OXO- 1-(PHENYLMETHYL)-3-(TETRAHYDRO-2H-PYRAN-4-YLAMINO)PROPYL)- 1,3,4,6-TETRAHYDRO(1,2)THIAZEPINO(5,4,3-CD)INDOLE-8- CARBOXAMIDE 2,2-DIOXIDE | HYDROLASE, MEMAPSIN-2, POLYMORPHISM, GLYCOPROTEIN, ASP-2, BACE-1, ZYMOGEN, PROTEASE, MEMBRANE, TRANSMEMBRANE, BETA-SECRETASE, DISULFIDE BOND, ASPARTYL PROTEASE, ALTERNATIVE SPLICING, BETA-SITE APP CLEAVING ENZYME
3ixk:C (TYR390) to (PRO421) POTENT BETA-SECRETASE 1 INHIBITOR | BACE, BETA-SECRETASE, STATINE, INHIBITOR, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN, DISULFIDE BOND
2wfp:A (GLU349) to (GLY370) CRYSTAL STRUCTURE OF MANNOSE 6-PHOSPHATE ISOMERASE (APO FORM) FROM SALMONELLA TYPHIMURIUM | ISOMERASE, APO-STRUCTURE, METAL-BINDING
1tu2:B (TYR147) to (ASN168) THE COMPLEX OF NOSTOC CYTOCHROME F AND PLASTOCYANIN DETERMIN WITH PARAMAGNETIC NMR. BASED ON THE STRUCTURES OF CYTOCHROME F AND PLASTOCYANIN, 10 STRUCTURES | ELECTRON TRANSPORT, PARAMAGNETIC, CHEMICAL SHIFT, COMPLEX FORMATION, DYNAMIC COMPLEX, PHOTOSYNTHESIS, PSEUDOCONTACT SHIFT, ELECTRON TRANSPORT PROTEINS COMPLEX
2wgg:C (GLY365) to (PHE404) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS C171Q KASA VARIANT WITH BOUND TLM | BETA KETOACYL SYNTHASE I, CYTOPLASM, TRANSFERASE, ACYLTRANSFERASE, LIPID SYNTHESIS, FATTY ACID BIOSYNTHESIS
2wgg:G (GLY365) to (PHE404) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS C171Q KASA VARIANT WITH BOUND TLM | BETA KETOACYL SYNTHASE I, CYTOPLASM, TRANSFERASE, ACYLTRANSFERASE, LIPID SYNTHESIS, FATTY ACID BIOSYNTHESIS
2hix:A (ARG512) to (SER534) ATP DEPENDENT DNA LIGASE FROM S. SOLFATARICUS BOUND TO ATP | ATP-DEPENDENT DNA LIGASE, DNA REPLICATION, LIGASE
2hiz:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA-SECRETASE (BACE) IN THE PRESENCE OF AN INHIBITOR | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
2hiz:C (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA-SECRETASE (BACE) IN THE PRESENCE OF AN INHIBITOR | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
2whw:A (GLU300) to (LEU319) SELECTIVE OXIDATION OF CARBOLIDE C-H BONDS BY ENGINEERED MACROLIDE P450 MONOOXYGENASE | ANTIBIOTIC BIOSYNTHESIS, CYP107L1, CYTOCHROME P450, HEME, IRON, MACROLIDE MONOOXYGENASE, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE ANTIBIOTIC BIOSYNTHESIS, PIKC
2whw:B (GLU300) to (LEU319) SELECTIVE OXIDATION OF CARBOLIDE C-H BONDS BY ENGINEERED MACROLIDE P450 MONOOXYGENASE | ANTIBIOTIC BIOSYNTHESIS, CYP107L1, CYTOCHROME P450, HEME, IRON, MACROLIDE MONOOXYGENASE, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE ANTIBIOTIC BIOSYNTHESIS, PIKC
2wi9:A (GLU300) to (LEU319) SELECTIVE OXIDATION OF CARBOLIDE C-H BONDS BY ENGINEERED MACROLIDE P450 MONOOXYGENASE | ANTIBIOTIC BIOSYNTHESIS, CYP107L1, CYTOCHROME P450, HEME, IRON, MACROLIDE MONOOXYGENASE, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE ANTIBIOTIC BIOSYNTHESIS, PIKC
2wi9:B (GLU300) to (LEU319) SELECTIVE OXIDATION OF CARBOLIDE C-H BONDS BY ENGINEERED MACROLIDE P450 MONOOXYGENASE | ANTIBIOTIC BIOSYNTHESIS, CYP107L1, CYTOCHROME P450, HEME, IRON, MACROLIDE MONOOXYGENASE, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE ANTIBIOTIC BIOSYNTHESIS, PIKC
3iyf:A (GLY319) to (GLY349) ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | GROUP II CHAPERONIN, PROTEIN FOLDING, MM-CPN, SINGLE PARTICLE RECONSTRUCTION, METHANOCOCCUS MARIPALUDIS, CHAPERONE, ATP-BINDING, NUCLEOTIDE-BINDING
3iyf:C (GLY319) to (GLY349) ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | GROUP II CHAPERONIN, PROTEIN FOLDING, MM-CPN, SINGLE PARTICLE RECONSTRUCTION, METHANOCOCCUS MARIPALUDIS, CHAPERONE, ATP-BINDING, NUCLEOTIDE-BINDING
3iyf:D (GLY319) to (GLY349) ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | GROUP II CHAPERONIN, PROTEIN FOLDING, MM-CPN, SINGLE PARTICLE RECONSTRUCTION, METHANOCOCCUS MARIPALUDIS, CHAPERONE, ATP-BINDING, NUCLEOTIDE-BINDING
3iyf:E (GLY319) to (GLY349) ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | GROUP II CHAPERONIN, PROTEIN FOLDING, MM-CPN, SINGLE PARTICLE RECONSTRUCTION, METHANOCOCCUS MARIPALUDIS, CHAPERONE, ATP-BINDING, NUCLEOTIDE-BINDING
3iyf:F (GLY319) to (GLY349) ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | GROUP II CHAPERONIN, PROTEIN FOLDING, MM-CPN, SINGLE PARTICLE RECONSTRUCTION, METHANOCOCCUS MARIPALUDIS, CHAPERONE, ATP-BINDING, NUCLEOTIDE-BINDING
3iyf:G (GLY319) to (GLY349) ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | GROUP II CHAPERONIN, PROTEIN FOLDING, MM-CPN, SINGLE PARTICLE RECONSTRUCTION, METHANOCOCCUS MARIPALUDIS, CHAPERONE, ATP-BINDING, NUCLEOTIDE-BINDING
3iyf:I (GLY319) to (GLY349) ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | GROUP II CHAPERONIN, PROTEIN FOLDING, MM-CPN, SINGLE PARTICLE RECONSTRUCTION, METHANOCOCCUS MARIPALUDIS, CHAPERONE, ATP-BINDING, NUCLEOTIDE-BINDING
3iyf:J (GLY319) to (GLY349) ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | GROUP II CHAPERONIN, PROTEIN FOLDING, MM-CPN, SINGLE PARTICLE RECONSTRUCTION, METHANOCOCCUS MARIPALUDIS, CHAPERONE, ATP-BINDING, NUCLEOTIDE-BINDING
3iyf:K (GLY319) to (GLY349) ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | GROUP II CHAPERONIN, PROTEIN FOLDING, MM-CPN, SINGLE PARTICLE RECONSTRUCTION, METHANOCOCCUS MARIPALUDIS, CHAPERONE, ATP-BINDING, NUCLEOTIDE-BINDING
3iyf:L (GLY319) to (GLY349) ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | GROUP II CHAPERONIN, PROTEIN FOLDING, MM-CPN, SINGLE PARTICLE RECONSTRUCTION, METHANOCOCCUS MARIPALUDIS, CHAPERONE, ATP-BINDING, NUCLEOTIDE-BINDING
3iyf:O (GLY319) to (GLY349) ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | GROUP II CHAPERONIN, PROTEIN FOLDING, MM-CPN, SINGLE PARTICLE RECONSTRUCTION, METHANOCOCCUS MARIPALUDIS, CHAPERONE, ATP-BINDING, NUCLEOTIDE-BINDING
3iyf:P (GLY319) to (THR350) ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | GROUP II CHAPERONIN, PROTEIN FOLDING, MM-CPN, SINGLE PARTICLE RECONSTRUCTION, METHANOCOCCUS MARIPALUDIS, CHAPERONE, ATP-BINDING, NUCLEOTIDE-BINDING
3vs7:A (GLU118) to (ARG140) CRYSTAL STRUCTURE OF HCK COMPLEXED WITH A PYRAZOLO-PYRIMIDINE INHIBITOR 1-CYCLOPENTYL-3-(1H-PYRROLO[2,3-B]PYRIDIN-5-YL)-1H- PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2win:B (LYS1529) to (SER1551) C3 CONVERTASE (C3BBB) STABILIZED BY SCIN | SERINE PROTEASE, IMMUNE RESPONSE, INNATE IMMUNITY, ZYMOGEN, SECRETED, PROTEASE, GLYCATION, ALTERNATIVE PATHWAY, DISEASE MUTATION, HYDROLASE, CONVERTASE, COMPLEMENT, POLYMORPHISM, IMMUNE EVASION, IMMUNE SYSTEM
2win:D (LYS1529) to (SER1551) C3 CONVERTASE (C3BBB) STABILIZED BY SCIN | SERINE PROTEASE, IMMUNE RESPONSE, INNATE IMMUNITY, ZYMOGEN, SECRETED, PROTEASE, GLYCATION, ALTERNATIVE PATHWAY, DISEASE MUTATION, HYDROLASE, CONVERTASE, COMPLEMENT, POLYMORPHISM, IMMUNE EVASION, IMMUNE SYSTEM
2win:F (LYS1529) to (GLY1550) C3 CONVERTASE (C3BBB) STABILIZED BY SCIN | SERINE PROTEASE, IMMUNE RESPONSE, INNATE IMMUNITY, ZYMOGEN, SECRETED, PROTEASE, GLYCATION, ALTERNATIVE PATHWAY, DISEASE MUTATION, HYDROLASE, CONVERTASE, COMPLEMENT, POLYMORPHISM, IMMUNE EVASION, IMMUNE SYSTEM
2win:H (LYS1529) to (GLY1550) C3 CONVERTASE (C3BBB) STABILIZED BY SCIN | SERINE PROTEASE, IMMUNE RESPONSE, INNATE IMMUNITY, ZYMOGEN, SECRETED, PROTEASE, GLYCATION, ALTERNATIVE PATHWAY, DISEASE MUTATION, HYDROLASE, CONVERTASE, COMPLEMENT, POLYMORPHISM, IMMUNE EVASION, IMMUNE SYSTEM
2hm1:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA-SECRETASE (BACE) IN THE PRESENCE OF AN INHIBITOR (2) | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
1hw5:A (GLY45) to (GLY71) THE CAP/CRP VARIANT T127L/S128A | CAMP RECEPTOR PROTEIN, CATABOLITE ACTIVATOR PROTEIN (CAP) TRANSCRIPTION, ALLOSTERY, CAMP, CYCLIC AMP MUTANT, GENE REGULATION
1tws:A (ASP4) to (VAL28) DIHYDROPTEROATE SYNTHETASE FROM BACILLUS ANTHRACIS | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE
1twz:A (ASP4) to (PRO30) DIHYDROPTEROATE SYNTHETASE, WITH BOUND SUBSTRATE ANALOGUE PTP, FROM BACILLUS ANTHRACIS | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE
1twz:B (ASP4) to (LEU26) DIHYDROPTEROATE SYNTHETASE, WITH BOUND SUBSTRATE ANALOGUE PTP, FROM BACILLUS ANTHRACIS | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE
1hxd:B (ALA114) to (GLU140) CRYSTAL STRUCTURE OF E. COLI BIOTIN REPRESSOR WITH BOUND BIOTIN | LIGASE, REPRESSOR, BIOTIN, DNA-BINDING
3vv7:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA SECETASE IN COMPLEX WITH 2-AMINO-6-((1S,2R)- 2-(3'-METHOXYBIPHENYL-3-YL)CYCLOPROPYL)-3-METHYLPYRIMIDIN-4(3H)-ONE | ASPARTYL PROTEASE, BASE, BETA-SECRETASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2hqu:C (MET24) to (TYR54) HUMAN DUTPASE IN COMPLEX WITH ALPHA,BETA-IMINODUTP AND MAGNESIUM ION | JELLY-ROLL, PROTEIN-SUBSTRATE ANALOGUE LIGAND COMPLEX, HYDROLASE
4lu0:C (LYS10) to (MET31) CRYSTAL STRUCTURE OF 2-KETO-3-DEOXY-D-MANNO-OCTULOSONATE-8-PHOSPHATE SYNTHASE FROM PSEUDOMONAS AERUGINOSA. | TIM ALPHA-BETA BARREL, ALDOLASE, PHOPHOENOL PYRUVATE, ARABINOSE 5 PHOSPHATE, KDO8P, TRANSFERASE
1u5g:D (VAL148) to (MET173) CRYSTAL STRUCTURE OF THE PH DOMAIN OF SKAP-HOM | PH DOMAIN, SIGNALING PROTEIN
4lxc:A (THR422) to (ASP450) THE ANTIMICROBIAL PEPTIDASE LYSOSTAPHIN FROM STAPHYLOCOCCUS SIMULANS | PEPTIDASE FAMILY M23, PEPTIDOGLYCAN HYDROLASE, METALLOPEPTIDASE, PEPTIDOGLYCAN, HYDROLASE
4lxc:C (ILE425) to (ASP450) THE ANTIMICROBIAL PEPTIDASE LYSOSTAPHIN FROM STAPHYLOCOCCUS SIMULANS | PEPTIDASE FAMILY M23, PEPTIDOGLYCAN HYDROLASE, METALLOPEPTIDASE, PEPTIDOGLYCAN, HYDROLASE
4lxk:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE IN COMPLEX WITH COMPOUND 11D | STRUCTURE-BASED DRUG DESIGN, ASPARTYL PROTEASE, MEMBRANE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4lxk:C (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE IN COMPLEX WITH COMPOUND 11D | STRUCTURE-BASED DRUG DESIGN, ASPARTYL PROTEASE, MEMBRANE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4lxm:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE IN COMPLEX WITH COMPOUND 12A | STRUCTURE-BASED DRUG DESIGN, ASPARTYL PROTEASE, MEMBRANE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4lxm:C (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE IN COMPLEX WITH COMPOUND 12A | STRUCTURE-BASED DRUG DESIGN, ASPARTYL PROTEASE, MEMBRANE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
2hym:A (ASP9) to (THR37) NMR BASED DOCKING MODEL OF THE COMPLEX BETWEEN THE HUMAN TYPE I INTERFERON RECEPTOR AND HUMAN INTERFERON ALPHA-2 | INTERFERON RECEPTOR COMPLEX, IMMUNE SYSTEM
2i2x:O (LYS23) to (TYR45) CRYSTAL STRUCTURE OF METHANOL:COBALAMIN METHYLTRANSFERASE COMPLEX MTABC FROM METHANOSARCINA BARKERI | TIM BARREL AND HELIX BUNDLE (MTAB); ROSSMAN FOLD AND HELIX BUNDLE (MTAC), TRANSFERASE
1ug1:A (ASN25) to (GLY43) SH3 DOMAIN OF HYPOTHETICAL PROTEIN BAA76854.1 | STRUCTURAL GENOMICS, SH3 DOMAIN, HYPOTHETICAL PROTEIN BAA76854.1, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, UNKNOWN FUNCTION
3w7s:B (ARG165) to (SER190) ESCHERICHIA COLI K12 YGJK COMPLEXED WITH GLUCOSE | GH63, PROCESSING ALPHA-GLUCOSIDASE I, ALPHA/ALPHA BARREL, HYDROLASE
1iko:P (GLU119) to (ILE138) CRYSTAL STRUCTURE OF THE MURINE EPHRIN-B2 ECTODOMAIN | GREEK KEY, GLYCOSYLATION, SIGNALING PROTEIN
4m3c:D (ASN2) to (THR27) STRUCTURE OF A BINARY COMPLEX BETWEEN HOMOLOGOUS TETRAMERIC LEGUME LECTINS FROM BUTEA MONOSPERMA AND SPATHOLOBUS PARVIFLORUS SEEDS | SUGAR BINDING PROTEIN, BUTEA MONOSPERMA SEED LECTIN, BML, SPATHOLOBUS PARVIFLORUS SEED LECTIN, SPL
4m4r:F (LEU120) to (ALA142) EPHA4 ECTODOMAIN COMPLEX WITH EPHRIN A5 | EPH RECEPTOR EPHRIN COMPLEX, TRANSFERASE
4m52:B (ASN119) to (THR146) STRUCTURE OF MTB LPD BOUND TO SL827 | OXIDOREDUCTASE, FLAVOPROTEIN, GLYCOLYSIS, REDOX-ACTIVE CENTER
4m52:C (ASN119) to (THR146) STRUCTURE OF MTB LPD BOUND TO SL827 | OXIDOREDUCTASE, FLAVOPROTEIN, GLYCOLYSIS, REDOX-ACTIVE CENTER
1is7:B (ILE126) to (GLY155) CRYSTAL STRUCTURE OF RAT GTPCHI/GFRP STIMULATORY COMPLEX | ENZYME-REGULATORY PROTEIN COMPLEX, HYDROLASE/PROTEIN BINDING COMPLEX
1is7:D (ILE126) to (GLY155) CRYSTAL STRUCTURE OF RAT GTPCHI/GFRP STIMULATORY COMPLEX | ENZYME-REGULATORY PROTEIN COMPLEX, HYDROLASE/PROTEIN BINDING COMPLEX
1is7:E (ILE126) to (GLY155) CRYSTAL STRUCTURE OF RAT GTPCHI/GFRP STIMULATORY COMPLEX | ENZYME-REGULATORY PROTEIN COMPLEX, HYDROLASE/PROTEIN BINDING COMPLEX
1is7:J (ILE126) to (GLY155) CRYSTAL STRUCTURE OF RAT GTPCHI/GFRP STIMULATORY COMPLEX | ENZYME-REGULATORY PROTEIN COMPLEX, HYDROLASE/PROTEIN BINDING COMPLEX
4m7b:A (SER1124) to (ARG1159) HUMAN TANKYRASE 2 - CATALYTIC PARP DOMAIN IN COMPLEX WITH AN INHIBITOR UPF1854 | DIPHTHERIA TOXIN LIKE ADP-RIBOSE TRANSFERASE DOMAIN, POLY ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1is8:C (ILE126) to (GLY155) CRYSTAL STRUCTURE OF RAT GTPCHI/GFRP STIMULATORY COMPLEX PLUS ZN | ENZYME-REGULATORY PROTEIN COMPLEX, HYDROLASE/PROTEIN BINDING COMPLEX
1is8:G (ILE126) to (GLY155) CRYSTAL STRUCTURE OF RAT GTPCHI/GFRP STIMULATORY COMPLEX PLUS ZN | ENZYME-REGULATORY PROTEIN COMPLEX, HYDROLASE/PROTEIN BINDING COMPLEX
1is8:J (ILE126) to (GLY155) CRYSTAL STRUCTURE OF RAT GTPCHI/GFRP STIMULATORY COMPLEX PLUS ZN | ENZYME-REGULATORY PROTEIN COMPLEX, HYDROLASE/PROTEIN BINDING COMPLEX
3wb4:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA SECETASE IN COMPLEX WITH 2-AMINO-3,6- DIMETHYL-6-(2-PHENYLETHYL)-3,4,5,6-TETRAHYDROPYRIMIDIN-4-ONE | PROTEASE 2, ASP2, MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2, MEMAPSIN- 2, HYDROLASE
1usr:A (GLU401) to (PRO423) NEWCASTLE DISEASE VIRUS HEMAGGLUTININ-NEURAMINIDASE: EVIDENCE FOR A SECOND SIALIC ACID BINDING SITE AND IMPLICATIONS FOR FUSION | HYDROLASE, SIALIDASE, NEURAMINIDASE, HEMAGGLUTININ-NEURAMINIDASE, HEMAGGLUTININ, GLYCOPROTEIN
2x11:B (LEU124) to (ALA146) CRYSTAL STRUCTURE OF THE COMPLETE EPHA2 ECTODOMAIN IN COMPLEX WITH EPHRIN A5 RECEPTOR BINDING DOMAIN | RECEPTOR-SIGNALING PROTEIN COMPLEX, DEVELOPMENTAL PROTEIN, SIGNALING PLATFORM, KINASE, TRANSFERASE, NEUROGENESIS, RECEPTOR, CATARACT, APOPTOSIS, ERYTHROPOIETIN-PRODUCING HEPATOCELLULAR CARCINOMA, ANGIOGENESIS, SIGNALING PROTEIN
1uwv:A (MSE246) to (GLN265) CRYSTAL STRUCTURE OF RUMA, THE IRON-SULFUR CLUSTER CONTAINING E. COLI 23S RIBOSOMAL RNA 5-METHYLURIDINE METHYLTRANSFERASE | METHYLTRANSFERASE, RNA MODIFICATION, IRON-SULFUR CLUSTER, TRANSFERASE, RNA PROCESSING
2x2j:D (ILE164) to (ASP186) CRYSTAL STRUCTURE OF THE GRACILARIOPSIS LEMANEIFORMIS ALPHA- 1,4-GLUCAN LYASE WITH DEOXYNOJIRIMYCIN | STARCH BINDING DOMAIN, ANHYDROFRUCTOSE PATHWAY, LYASE, GLYCOSIDE HYDROLASE FAMILY 31
2ipo:D (MET1) to (HIS20) E. COLI ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH N- PHOSPHONACETYL-L-ASPARAGINE | ASPARTATE TRANSCARBAMOYLASE, ALLOSTERIC, INHIBITOR DESIGN, DOMAIN CLOSURE, TRANSFERASE
1j3l:C (VAL128) to (ASP146) STRUCTURE OF THE RNA-PROCESSING INHIBITOR RRAA FROM THERMUS THERMOPHILIS | VITAMINE K2, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
1j3l:F (VAL128) to (ASP146) STRUCTURE OF THE RNA-PROCESSING INHIBITOR RRAA FROM THERMUS THERMOPHILIS | VITAMINE K2, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
3wku:B (ASP50) to (PRO80) CRYSTAL STRUCTURE OF THE ANAEROBIC DESB-GALLATE COMPLEX | TYPE II EXTRADIOL DIOXYGENASE, DOMAIN-SWAP DIMER, EXTRADIOL DIOXYGENASE, FE2+ BINDING, OXIDOREDUCTASE
1j6p:A (ALA370) to (THR386) CRYSTAL STRUCTURE OF METAL-DEPENDENT HYDROLASE OF CYTOSINEDEMANIASE/CHLOROHYDROLASE FAMILY (TM0936) FROM THERMOTOGA MARITIMA AT 1.9 A RESOLUTION | STRUCTURAL GENOMICS, TM0936, JCSG, METAL-DEPENDENT HYDROLASE OF CYTOSINEDEMANIASE/CHLOROHYDROLASE FAMILY, PSI, PROTEIN STRUCTURE INITIATIVE, JOINT CENTER FOR STRUCTURAL GENOMICS, HYDROLASE
5aku:B (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF TNKS2 IN COMPLEX WITH 2-(4-TERT- BUTYLPHENYL)-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5akw:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF TNKS2 IN COMPLEX WITH 2-(4- CHLOROPHENYL)-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5al1:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF TNKS2 IN COMPLEX WITH 2-(4-TERT- BUTYLPHENYL)-1H,2H,3H,4H-PYRIDO(2,3-D)PYRIMIDIN-4-ONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5al3:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF TNKS2 IN COMPLEX WITH 2-(2,4- DICHLOROPHENYL)-1-METHYL-1H,2H,3H,4H-PYRIDO(2,3-D) PYRIMIDIN-4-ONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5al4:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF TNKS2 IN COMPLEX WITH 2-(4- METHYLPIPERAZIN-1-YL)-3,4,5,6,7,8-HEXAHYDROQUINAZOLIN-4-ONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mmy:A (ASP751) to (SER791) INTEGRIN ALPHAVBETA3 ECTODOMAIN BOUND TO THE TENTH DOMAIN OF FIBRONECTIN WITH THE IAKGDWND MOTIF | INTEGRIN, A DOMAIN, HYBRID DOMAIN, PSI, EGF REPEATS, BETA TA THIGH, BETA PROPELLER, RGD MOTIF, FIBRONECTIN, VITRONECTIN, CELL ADHESION
4mol:D (HIS299) to (LEU318) PYRANOSE 2-OXIDASE H167A MUTANT WITH 2-FLUORINATED GALACTOSE | GMC OXIDOREDUCTASE, PHBH FOLD, HOMOTETRAMER, FAD-BINDING, SUBSTRATE COMPLEX, FLAVINYLATION, INTRACELLULAR, OXIDOREDUCTASE
3wpm:B (ASP50) to (PRO80) CRYSTAL STRUCTURE OF THE ANAEROBIC DESB-GALLATE COMPLEX BY CO- CRYSTALLIZATION | TYPE II EXTRADIOL DIOXYGENASE, DOMAIN-SWAP DIMER, EXTRADIOL DIOXYGENASE, FE2+ BINDING, OXIDOREDUCTASE
1jj7:A (LEU502) to (GLY538) CRYSTAL STRUCTURE OF THE C-TERMINAL ATPASE DOMAIN OF HUMAN TAP1 | P-LOOP, ABC ATPASE DOMAIN, HELICAL DOMAIN, PROTEIN TRANSPORT
1jjc:B (GLU281) to (ILE300) CRYSTAL STRUCTURE AT 2.6A RESOLUTION OF PHENYLALANYL-TRNA SYNTHETASE COMPLEXED WITH PHENYLALANYL-ADENYLATE IN THE PRESENCE OF MANGANESE | HETERODIMER, PHENYLALANYL-TRNA, THERMUS THERMOPHILUS, LIGASE
2j3j:B (MET1001) to (LEU1046) CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA DOUBLE BOND REDUCTASE (AT5G16970)-TERNARY COMPLEX I | OXIDOREDUCTASE, P-COUMARYL ALDEHYDE, ARABIDOPSIS THALIANA, NADP, TERNARY COMPLEX, DOUBLE BOND REDUCTASE (AT5G16970)
2j3i:B (MET1001) to (TYR1047) CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA DOUBLE BOND REDUCTASE (AT5G16970)-BINARY COMPLEX | DOUBLE BOND REDUCTASE (AT5G16970), BINARY COMPLEX NADP, APO FORM, OXIDOREDUCTASE, ARABIDOPSIS THALIANA
3wr8:A (ASP50) to (PRO80) CRYSTAL STRUCTURE OF DESB FROM SPHINGOBIUM SP. STRAIN SYK-6 | OXIDOREDUCTASE, EXTRADIOL DIOXYGENASE, FE2+ BINDING, DOMAIN-SWAP DIMER
3wr8:B (ASP50) to (PRO80) CRYSTAL STRUCTURE OF DESB FROM SPHINGOBIUM SP. STRAIN SYK-6 | OXIDOREDUCTASE, EXTRADIOL DIOXYGENASE, FE2+ BINDING, DOMAIN-SWAP DIMER
3wrb:A (ASP50) to (PRO80) CRYSTAL STRUCTURE OF THE ANAEROBIC H124F DESB-GALLATE COMPLEX | OXIDOREDUCTASE, EXTRADIOL DIOXYGENASE, FE2+ BINDING, DOMAIN-SWAP DIMER
2xgj:A (GLU681) to (LYS700) STRUCTURE OF MTR4, A DEXH HELICASE INVOLVED IN NUCLEAR RNA PROCESSING AND SURVEILLANCE | HYDROLASE-RNA COMPLEX, HYDROLASE, TRAMP, EXOSOME, DEAD, NUCLEOTIDE-BINDING
4msg:A (SER1277) to (LYS1312) CRYSTAL STRUCTURE OF TANKYRASE 1 WITH COMPOUND 22 | TANKYRASE, PARP, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1jov:A (VAL161) to (SER196) CRYSTAL STRUCTURE ANALYSIS OF HI1317 | HYPOTHETICAL PROTEIN, STRUCTURE 2 FUNCTION PROJECT, S2F, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
3wt3:A (GLY131) to (PRO148) NEW CRYSTAL FORM OF A HYPERTHERMOPHILIC ENDOCELLULASE | BETA-JELLY ROLL, GLYCOSIDE HYDROLASE, HYDROLASE
3wt3:B (GLY131) to (PRO148) NEW CRYSTAL FORM OF A HYPERTHERMOPHILIC ENDOCELLULASE | BETA-JELLY ROLL, GLYCOSIDE HYDROLASE, HYDROLASE
2j7i:B (GLY36) to (LYS58) ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETERODIMER | COILED COIL, POLYMORPHISM, GLYCOPROTEIN, CELL ADHESION, EGFR DOWNREGULATION, IMMUNOGLOBULIN DOMAIN, TRANSMEMBRANE, PHOSPHORYLATION, ADAPTOR PROTEIN, CMS, CD2AD, MEMBRANE, SH3 DOMAIN, SH3-BINDING, SH3 DOMAIN RECOGNITION, PROTEIN BINDING
4mwa:E (ARG11) to (THR34) 1.85 ANGSTROM CRYSTAL STRUCTURE OF GCPE PROTEIN FROM BACILLUS ANTHRACIS | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, GCPE PROTEIN, 4-HYDROXY-3-METHYLBUT-2-EN-1-YL DIPHOSPHATE SYNTHASE, OXIDOREDUCTASE
4mwa:G (ARG11) to (THR34) 1.85 ANGSTROM CRYSTAL STRUCTURE OF GCPE PROTEIN FROM BACILLUS ANTHRACIS | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, GCPE PROTEIN, 4-HYDROXY-3-METHYLBUT-2-EN-1-YL DIPHOSPHATE SYNTHASE, OXIDOREDUCTASE
4mx3:B (GLY296) to (GLY323) CRYSTAL STRUCTURE OF PKA RIALPHA HOMODIMER | PKA, RIALPHA HOMODIMER, COOPERATIVE CAMP BINDING, CARNEY COMPLEX DISEASE, SIGNALING PROTEIN
1vs1:A (ARG23) to (ALA43) CRYSTAL STRUCTURE OF 3-DEOXY-D-ARABINO-HEPTULOSONATE-7- PHOSPHATE SYNTHASE (DAHP SYNTHASE) FROM AEROPYRUM PERNIX IN COMPLEX WITH MN2+ AND PEP | (BETA/ALPHA)8 BARREL, TRANSFERASE
1vs1:B (ARG23) to (ALA43) CRYSTAL STRUCTURE OF 3-DEOXY-D-ARABINO-HEPTULOSONATE-7- PHOSPHATE SYNTHASE (DAHP SYNTHASE) FROM AEROPYRUM PERNIX IN COMPLEX WITH MN2+ AND PEP | (BETA/ALPHA)8 BARREL, TRANSFERASE
4myw:D (GLY120) to (LEU168) STRUCTURE OF HSV-2 GD BOUND TO NECTIN-1 | IGV-LIKE CORE, N-/C-TERMINAL EXTENSIONS, TANDEM ARRANGED V-C-C IG- LIKE DOMAINS, RECEPTOR BINDING, CELL SURFACE ATTACHMENT, VIRAL, CELLULAR SURFACE, VIRAL PROTEIN-CELL ADHESION COMPLEX
1jva:B (THR329) to (PRO369) CRYSTAL STRUCTURE OF THE VMA1-DERIVED ENDONUCLEASE BEARING THE N AND C EXTEIN PROPEPTIDES | PROTEIN-SPLICING, VMA1-DERIVED ENDONUCLEASE, INTEIN, THIAZOLIDINE INTERMEDIATE, VDE, HYDROLASE
1w0g:A (ASP380) to (ILE396) CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 3A4 | OXIDOREDUCTASE, NIFEDIPINE OXIDASE, CYTOCHROME P450, ELECTRON TRANSPORT, MONOOXYGENASE
1w0p:A (VAL352) to (THR372) VIBRIO CHOLERAE SIALIDASE WITH ALPHA-2,6-SIALYLLACTOSE | HYDROLASE, VIBRIO CHOLERAE, SIALIDASE, NEURAMINIDASE, LECTIN
1w18:B (SER485) to (GLY507) CRYSTAL STRUCTURE OF LEVANSUCRASE FROM GLUCONACETOBACTER DIAZOTROPHICUS | TRANSFERASE, FRUCTOSYL TRANSFERASE, GLYCOSYLTRANSFERASE
2jem:A (MET73) to (TRP98) NATIVE FAMILY 12 XYLOGLUCANASE FROM BACILLUS LICHENIFORMIS | PLANT CELL WALL, GLYCOSIDASE, XYLOGLUCANASE, HYDROLASE, FAMILY 12
5b5t:C (GLY97) to (THR150) CRYSTAL STRUCTURE OF ESCHERICHIA COLI GAMMA-GLUTAMYLTRANSPEPTIDASE IN COMPLEX WITH PEPTIDYL PHOSPHONATE INHIBITOR 1B | GLUTATHIONE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5bny:E (GLY285) to (GLY318) CRYSTAL STRUCTURE OF HEMAGGLUTININ OF A/CHICKEN/GUANGDONG/S1311/2010 (H6N6) | INFLUENZA, HEAMGGLUTININ, VIRAL PROTEIN
1w96:A (LEU475) to (ASP503) CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE DOMAIN OF ACETYL- COENZYME A CARBOXYLASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH SORAPHEN A | LIGASE, OBESITY, DIABETES, FATTY ACID METABOLISM, STRUCTURE-BASED DRUG DESIGN, ALLOSTERIC INHIBITION, POLYKETIDE
1w96:B (THR474) to (ASP503) CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE DOMAIN OF ACETYL- COENZYME A CARBOXYLASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH SORAPHEN A | LIGASE, OBESITY, DIABETES, FATTY ACID METABOLISM, STRUCTURE-BASED DRUG DESIGN, ALLOSTERIC INHIBITION, POLYKETIDE
4nc4:B (GLY353) to (ILE374) CRYSTAL STRUCTURE OF PHOTORECEPTOR ATUVR8 MUTANT W285F AND LIGHT- INDUCED STRUCTURAL CHANGES AT 120K | 7-BLADE BETA-PROPELLER, SIGNALING PROTEIN
4nc4:D (GLY353) to (ILE374) CRYSTAL STRUCTURE OF PHOTORECEPTOR ATUVR8 MUTANT W285F AND LIGHT- INDUCED STRUCTURAL CHANGES AT 120K | 7-BLADE BETA-PROPELLER, SIGNALING PROTEIN
5bv6:A (GLY329) to (GLY356) PKG II'S CARBOXYL TERMINAL CYCLIC NUCLEOTIDE BINDING DOMAIN (CNB-B) IN A COMPLEX WITH CGMP | CYCLIC GMP-DEPENDENT PROTEIN KINASE TYPE II, TRANSFERASE
4neh:A (LYS917) to (PRO947) AN INTERNAL LIGAND-BOUND, METASTABLE STATE OF A LEUKOCYTE INTEGRIN, AXB2 | ROSSMANN FOLD,, COMPLEMENT RECEPTOR, IC3B, ICAM-1, FIBRINOGEN, DENATURATED PROTEINS, HEPARIN, N-LINKED GLYCOSYLATION, MEMBRANE, CELL ADHESION
2y0f:C (PRO9) to (MET29) STRUCTURE OF GCPE (ISPG) FROM THERMUS THERMOPHILUS HB27 | OXIDOREDUCTASE, ISOPRENOID BIOSYNTHESIS, NON-MEVALONATE PATHWAY
2jm9:A (ASP14) to (LEU33) R21A SPC-SH3 BOUND | SH3 DOMAIN, P41-BOUND, STRUCTURAL PROTEIN
3zk5:A (GLU300) to (LEU319) PIKC D50N MUTANT BOUND TO THE 10-DML ANALOG WITH THE 3-(N,N-DIMETHYLAMINO)ETHANOATE ANCHORING GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
3zk5:B (GLU300) to (LEU319) PIKC D50N MUTANT BOUND TO THE 10-DML ANALOG WITH THE 3-(N,N-DIMETHYLAMINO)ETHANOATE ANCHORING GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
3zkg:A (TYR354) to (GLY384) BACE2 MUTANT APO STRUCTURE | HYDROLASE
3zkg:B (TYR354) to (GLY384) BACE2 MUTANT APO STRUCTURE | HYDROLASE
3zki:A (TYR354) to (GLY384) BACE2 MUTANT STRUCTURE WITH LIGAND | HYDROLASE
3zki:B (TYR354) to (GLY384) BACE2 MUTANT STRUCTURE WITH LIGAND | HYDROLASE
3zkm:A (TYR354) to (GLY384) BACE2 FAB COMPLEX | HYDROLASE-IMMUNE SYSTEM COMPLEX, HYDROLASE, ASPARTYL PROTEASE/FAB COMPLEX
1kbt:A (ARG1) to (LEU20) SOLUTION STRUCTURE OF CARDIOTOXIN IV, NMR, 12 STRUCTURES | VENOM, CYTOTOXIN, CARDIOTOXIN, MULTIGENE FAMILY
3zkn:B (TYR354) to (GLY384) BACE2 FAB INHIBITOR COMPLEX | IMMUNE SYSTEM-HYDROLASE COMPLEX, FAB COMPLEX
3zkq:A (TYR354) to (SER383) BACE2 XAPERONE COMPLEX | HYDROLASE-IMMUNE SYSTEM COMPLEX, NANOBODY
3zkx:A (TYR354) to (GLY384) TERNARY BACE2 XAPERONE COMPLEX | HYDROLASE
1kca:A (PHE141) to (PRO176) CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR C-TERMINAL DOMAIN OCTAMER | GENE REGULATION, DNA-BINDING, LAMBDA REPRESSOR, PROTEIN OLIGOMERIZATION, DNA-LOOPING
1kca:C (PHE141) to (PRO176) CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR C-TERMINAL DOMAIN OCTAMER | GENE REGULATION, DNA-BINDING, LAMBDA REPRESSOR, PROTEIN OLIGOMERIZATION, DNA-LOOPING
1kca:E (PHE141) to (PRO176) CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR C-TERMINAL DOMAIN OCTAMER | GENE REGULATION, DNA-BINDING, LAMBDA REPRESSOR, PROTEIN OLIGOMERIZATION, DNA-LOOPING
4nil:A (ASP4) to (PHE33) CRYSTAL STRUCTURE OF B. ANTHRACIS DHPS WITH COMPOUND 5: 4- [(TRIFLUOROMETHYL)SULFANYL]BENZAMIDE | TIM BARREL, TRANSFERASE, PTERIN AND PABA BINDING, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4nil:B (ASP4) to (LEU26) CRYSTAL STRUCTURE OF B. ANTHRACIS DHPS WITH COMPOUND 5: 4- [(TRIFLUOROMETHYL)SULFANYL]BENZAMIDE | TIM BARREL, TRANSFERASE, PTERIN AND PABA BINDING, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2kfb:A (CYS42) to (ALA64) THE STRUCTURE OF THE CATARACT CAUSING P23T MUTANT OF HUMAN GAMMA-D CRYSTALLIN | CRYSTALLIN, CATARACT, PROTEIN, LENS, DISEASE MUTATION, EYE LENS PROTEIN, OXIDATION, SENSORY TRANSDUCTION, VISION, STRUCTURAL PROTEIN
4nir:A (ASP4) to (VAL28) CRYSTAL STRUCTURE OF B. ANTHRACIS DHPS WITH COMPOUND 6: 3-[6- (TRIFLUOROMETHYL)-1H-BENZIMIDAZOL-2-YL]PROPAN-1-OL | TIM BARREL, TIM BAREL, TRANSFERASE, PTERIN, PABA, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4nj4:A (VAL124) to (TYR141) CRYSTAL STRUCTURE OF HUMAN ALKBH5 | DOUBLE-STRANDED BETA HELIX, JELLY-ROLL MOTIF, DIOXYGENASE, RNA DEMETHYLASE, RNA, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4nj4:B (VAL124) to (TYR141) CRYSTAL STRUCTURE OF HUMAN ALKBH5 | DOUBLE-STRANDED BETA HELIX, JELLY-ROLL MOTIF, DIOXYGENASE, RNA DEMETHYLASE, RNA, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
2y46:A (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG IN COMPLEX WITH MYCINAMICIN IV IN C 2 2 21 SPACE GROUP | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
2y46:B (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG IN COMPLEX WITH MYCINAMICIN IV IN C 2 2 21 SPACE GROUP | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
2y46:C (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG IN COMPLEX WITH MYCINAMICIN IV IN C 2 2 21 SPACE GROUP | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
2klj:A (GLY41) to (ALA64) SOLUTION STRUCTURE OF GAMMAD-CRYSTALLIN WITH RDC AND SAXS | GAMMAD-CRYSTALLIN, 3D STRUCTURE, RDC, SAXS, CATARACT, DISEASE MUTATION, EYE LENS PROTEIN, OXIDATION, POLYMORPHISM, SENSORY TRANSDUCTION, VISION, STRUCTURAL PROTEIN
3zmg:A (TYR403) to (PRO434) CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH CHEMICAL LIGAND | HYDROLASE
2y5n:A (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG IN COMPLEX WITH MYCINAMICIN V IN P21 SPACE GROUP | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
2y5n:B (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG IN COMPLEX WITH MYCINAMICIN V IN P21 SPACE GROUP | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
2y5z:A (GLU292) to (SER310) MIXED-FUNCTION P450 MYCG IN COMPLEX WITH MYCINAMICIN III IN C2221 SPACE GROUP | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
2y5z:B (GLU292) to (SER310) MIXED-FUNCTION P450 MYCG IN COMPLEX WITH MYCINAMICIN III IN C2221 SPACE GROUP | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
2y5z:C (GLU292) to (SER310) MIXED-FUNCTION P450 MYCG IN COMPLEX WITH MYCINAMICIN III IN C2221 SPACE GROUP | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
1wqs:C (ILE47) to (GLU75) CRYSTAL STRUCTURE OF NOROVIRUS 3C-LIKE PROTEASE | CRYSTAL STRUCTURE, NOROVIRUS, 3C-LIKE PROTEASE, CHYMOTRYPSIN LIKE PROTEASE, OXYANION HOLE, NORWALK-LIKE VIRUS, HYDROLASE
3zpi:A (GLU300) to (LEU319) PIKC D50N MUTANT IN P21 SPACE GROUP | PIKROMYCIN BIOSYNTHESIS, ELECTRON TRANSPORT
3zpi:B (GLU300) to (LEU319) PIKC D50N MUTANT IN P21 SPACE GROUP | PIKROMYCIN BIOSYNTHESIS, ELECTRON TRANSPORT
2y98:A (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG IN COMPLEX WITH MYCINAMICIN IV IN P21212 SPACE GROUP | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
1wxr:A (TYR147) to (GLY168) CRYSTAL STRUCTURE OF HEME BINDING PROTEIN, AN AUTOTRANSPORTER HEMOGLOBINE PROTEASE FROM PATHOGENIC ESCHERICHIA COLI | HEMOGLOBINE PROTEASE, AUTOTRANSPORTER, BETA HELIX, HEME UPTAKE, SPATE, HYDROLASE
1wxx:A (GLU171) to (ALA194) CRYSTAL STRUCTURE OF TT1595, A PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE FROM THERMUS THERMOPHILLUS HB8 | THERMUS THERMOPHILLUS, METHYLTRANSFERASE, ADOMET, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, TRANSFERASE
3zsn:A (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG F286A MUTANT IN COMPLEX WITH MYCINAMICIN IV | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
3zsn:B (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG F286A MUTANT IN COMPLEX WITH MYCINAMICIN IV | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
3zsn:C (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG F286A MUTANT IN COMPLEX WITH MYCINAMICIN IV | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
3jby:B (ALA76) to (SER105) CRYO-ELECTRON MICROSCOPY STRUCTURE OF RAG PAIRED COMPLEX (C2 SYMMETRY) | RAG1, RAG2, V(D)J RECOMBINATION, PAIRED COMPLEX, ANTIGEN RECEPTOR GENE RECOMBINATION, T AND B CELL DEVELOPMENT, RECOMBINATION-DNA COMPLEX
2m3t:A (THR46) to (GLU69) SOLUTION-STATE NMR STRUCTURE OF WILD-TYPE HUMAN GAMMA(S)-CRYSTALLIN | GAMMA-S, EYE LENS, AGGREGATION, CRYSTALLIN, CATARACT, CRYGS, STRUCTURAL PROTEIN
2ycl:B (VAL15) to (ASP55) COMPLETE STRUCTURE OF THE CORRINOID,IRON-SULFUR PROTEIN INCLUDING THE N-TERMINAL DOMAIN WITH A 4FE-4S CLUSTER | TRANSFERASE
4nrw:B (ALA98) to (PHE121) MVNEI1-G86D | ZINC-LESS FINGER DOMAIN, DNA GLYCOSYLASE, HELIX TWO-TURNS HELIX MOTIF, THF, DNA LYASE, HYDROLASE, LYASE-DNA COMPLEX
2ydt:A (TYR100) to (ILE135) STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEXE WITH AN IMINOSUGAR INHIBITOR | HYDROLASE
2yew:B (ALA300) to (ALA351) MODELING BARMAH FOREST VIRUS STRUCTURAL PROTEINS | ALPHAVIRUS, VIRUS, MOLECULAR DYNAMICS
1x6u:A (LYS4) to (MET25) KDO8P SYNTHASE IN IT'S BINARY COMPLEX WITH THE PRODUCT KDO8P | KDO8P, TRANSFERASE
4nvp:A (VAL639) to (GLY659) STRUCTURE OF THE CYCLIC NUCLEOTIDE-BINDING DOMAIN OF HCN4 CHANNEL COMPLEXED WITH 7-CH-CAMP | CYCLIC NUCLEOTIDE BINDING DOMAIN, POTASSIUM/SODIUM HYPERPOLARIZATION- ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL, CYTOPLASMIC DOMAIN, TRANSPORT PROTEIN
5c5c:A (ASN454) to (THR484) HUMAN METABOTROPIC GLUTAMATE RECEPTOR 7, EXTRACELLULAR LIGAND BINDING DOMAIN | GLUTAMATE RECEPTORS, GLUTAMIC ACID BINDING, MGLUR7, SIGNALING PROTEIN, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
4nwv:B (PRO279) to (VAL305) CRYSTAL STRUCTURE OF ORSAY VIRUS-LIKE PARTICLE | BETA BARREL, VIRUS
2ygx:A (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG IN P21 SPACE GROUP | ELECTRON TRANSPORT, MYCINAMICIN BIOSYNTHESIS, METAL BINDING
2ygx:B (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG IN P21 SPACE GROUP | ELECTRON TRANSPORT, MYCINAMICIN BIOSYNTHESIS, METAL BINDING
2ygx:C (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG IN P21 SPACE GROUP | ELECTRON TRANSPORT, MYCINAMICIN BIOSYNTHESIS, METAL BINDING
2ygx:D (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG IN P21 SPACE GROUP | ELECTRON TRANSPORT, MYCINAMICIN BIOSYNTHESIS, METAL BINDING
2nni:A (ASP373) to (LEU390) CYP2C8DH COMPLEXED WITH MONTELUKAST | CYP2C8; HUMAN P450 2C8; MONOOXYGENASES; MONTELUKAST; SINGULAIR; INHIBITOR COMPLEX; PALMITIC ACI, OXIDOREDUCTASE,ELECTRON TRANSPORT
1l1d:B (HIS480) to (PRO505) CRYSTAL STRUCTURE OF THE C-TERMINAL METHIONINE SULFOXIDE REDUCTASE DOMAIN (MSRB) OF N. GONORRHOEAE PILB | CACODYLATE COMPLEX, CYS-ARG-ASP CATALYTIC TRIAD, MET-R(O) REDUCTASE, OXIDOREDUCTASE, MSRB
5cad:A (HIS195) to (LEU214) CRYSTAL STRUCTURE OF THE VICILIN FROM SOLANUM MELONGENA REVEALED EXISTENCE OF DIFFERENT ANIONIC LIGANDS IN STRUCTURALLY SIMILAR POCKETS | SOLANACEAE; SOLANUM MELONGENA;7S VICILIN; SM80.1, PLANT PROTEIN
2yjt:A (VAL129) to (ASP147) CRYSTAL STRUCTURE OF E. COLI DEAD-BOX PROTEIN SRMB BOUND TO REGULATOR OF RIBONUCLEASE ACTIVITY A (RRAA) | HYDROLASE INHIBITOR-HYDROLASE COMPLEX, DEAD BOX RNA HELICASES
4o2w:A (GLY4052) to (ILE4073) CRYSTAL STRUCTURE OF THE THIRD RCC1-LIKE DOMAIN OF HERC1 | RCC1, RLD, BETA-PROPELLER, HERC1, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, LIGASE
4o2w:A (GLY4159) to (VAL4180) CRYSTAL STRUCTURE OF THE THIRD RCC1-LIKE DOMAIN OF HERC1 | RCC1, RLD, BETA-PROPELLER, HERC1, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, LIGASE
4o2w:B (GLY4107) to (ILE4128) CRYSTAL STRUCTURE OF THE THIRD RCC1-LIKE DOMAIN OF HERC1 | RCC1, RLD, BETA-PROPELLER, HERC1, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, LIGASE
4o2w:D (GLY4107) to (ILE4128) CRYSTAL STRUCTURE OF THE THIRD RCC1-LIKE DOMAIN OF HERC1 | RCC1, RLD, BETA-PROPELLER, HERC1, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, LIGASE
4o2w:D (GLY4316) to (VAL4337) CRYSTAL STRUCTURE OF THE THIRD RCC1-LIKE DOMAIN OF HERC1 | RCC1, RLD, BETA-PROPELLER, HERC1, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, LIGASE
3jr4:A (VAL96) to (VAL119) MUTM INTERROGATING AN EXTRAHELICAL G | DNA GLYCOSYLASE, DNA REPAIR, DAMAGE SEARCH, BASE EXTRUSION, DISULFIDE CROSSLINKING, DNA DAMAGE, DNA-BINDING, GLYCOSIDASE, HYDROLASE, LYASE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, ZINC, ZINC-FINGER, LYASE/DNA COMPLEX
5cct:A (GLN6) to (GLU33) STAPHYLOCOCCUS BACTERIOPHAGE 80ALPHA DUTPASE G164S MUTANT WITH DUPNHPP. | PHAGE, PATHOGENICITY ISLAND, SAPI INDUCTION, GENE TRANSFER, MOONLIGHTING PROTEINS, DUT, DUTP, G PROTEIN, P-LOOP, HYDROLASE
3js3:A (LYS2) to (LYS26) CRYSTAL STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE (AROD) FROM CLOSTRIDIUM DIFFICILE WITH COVALENT REACTION INTERMEDIATE | TYPE I 3-DEHYDROQUINATE DEHYDRATASE, AROD, COVALENT REACTION INTERMEDIATE, AMINO-ACID BIOSYNTHESIS, AROMATIC AMINO ACID BIOSYNTHESIS, LYASE, SCHIFF BASE, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
3js3:B (LYS2) to (LYS26) CRYSTAL STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE (AROD) FROM CLOSTRIDIUM DIFFICILE WITH COVALENT REACTION INTERMEDIATE | TYPE I 3-DEHYDROQUINATE DEHYDRATASE, AROD, COVALENT REACTION INTERMEDIATE, AMINO-ACID BIOSYNTHESIS, AROMATIC AMINO ACID BIOSYNTHESIS, LYASE, SCHIFF BASE, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
3js3:C (LYS2) to (LYS26) CRYSTAL STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE (AROD) FROM CLOSTRIDIUM DIFFICILE WITH COVALENT REACTION INTERMEDIATE | TYPE I 3-DEHYDROQUINATE DEHYDRATASE, AROD, COVALENT REACTION INTERMEDIATE, AMINO-ACID BIOSYNTHESIS, AROMATIC AMINO ACID BIOSYNTHESIS, LYASE, SCHIFF BASE, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
2ntr:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BACE-1 BOUND TO INHIBITOR | BACE, ASPARTYL PROTEASE, HYDROLASE
2nub:A (LYS238) to (THR260) STRUCTURE OF AQUIFEX AEOLICUS ARGONUATE | RNASEH, ARGONAUTE, RIBONUCLEASE, RNAI, RISC, SIGNALING PROTEIN
4a0o:I (LYS334) to (GLY364) SYMMETRY-FREE CRYO-EM MAP OF TRIC IN THE NUCLEOTIDE-FREE (APO) STATE | CHAPERONE, CHAPERONIN, PROTEIN FOLDING
2nv0:B (PHE116) to (GLU141) STRUCTURE OF THE GLUTAMINASE SUBUNIT PDX2 (YAAE) OF PLP SYNTHASE FROM BACILLUS SUBTILIS | 3-LAYER(ABA) SANDWICH, ROSSMANN FOLD, GLUTAMINASE, TRANSFERASE
2nv2:B (SER115) to (GLU141) STRUCTURE OF THE PLP SYNTHASE COMPLEX PDX1/2 (YAAD/E) FROM BACILLUS SUBTILIS | (BETA/ALPHA)8-BARREL,3-LAYER(ABA) SANDWICH, PLP SYNTHASE COMPLEX, LYASE-TRANSFERASE COMPLEX
2nv2:R (SER115) to (GLU141) STRUCTURE OF THE PLP SYNTHASE COMPLEX PDX1/2 (YAAD/E) FROM BACILLUS SUBTILIS | (BETA/ALPHA)8-BARREL,3-LAYER(ABA) SANDWICH, PLP SYNTHASE COMPLEX, LYASE-TRANSFERASE COMPLEX
2nv2:V (SER115) to (GLU141) STRUCTURE OF THE PLP SYNTHASE COMPLEX PDX1/2 (YAAD/E) FROM BACILLUS SUBTILIS | (BETA/ALPHA)8-BARREL,3-LAYER(ABA) SANDWICH, PLP SYNTHASE COMPLEX, LYASE-TRANSFERASE COMPLEX
2nv2:X (SER115) to (GLU141) STRUCTURE OF THE PLP SYNTHASE COMPLEX PDX1/2 (YAAD/E) FROM BACILLUS SUBTILIS | (BETA/ALPHA)8-BARREL,3-LAYER(ABA) SANDWICH, PLP SYNTHASE COMPLEX, LYASE-TRANSFERASE COMPLEX
1l7v:C (VAL4) to (PRO34) BACTERIAL ABC TRANSPORTER INVOLVED IN B12 UPTAKE | ABC TRANSPORTER, INTEGRAL MEMBRANE PROTEIN, ATP BINDING CASSETTE, ATP HYDROLYSIS, VITAMIN B12, TRANSPORT PROTEIN/HYDROLASE COMPLEX
1l7v:D (VAL4) to (PRO34) BACTERIAL ABC TRANSPORTER INVOLVED IN B12 UPTAKE | ABC TRANSPORTER, INTEGRAL MEMBRANE PROTEIN, ATP BINDING CASSETTE, ATP HYDROLYSIS, VITAMIN B12, TRANSPORT PROTEIN/HYDROLASE COMPLEX
1l9w:A (MET1) to (ARG25) CRYSTAL STRUCTURE OF 3-DEHYDROQUINASE FROM SALMONELLA TYPHI COMPLEXED WITH REACTION PRODUCT | TIM-BARREL, COMPLEX WITH PRODUCT, LYASE
1l9w:B (MET1) to (ARG25) CRYSTAL STRUCTURE OF 3-DEHYDROQUINASE FROM SALMONELLA TYPHI COMPLEXED WITH REACTION PRODUCT | TIM-BARREL, COMPLEX WITH PRODUCT, LYASE
1l9w:C (MET1) to (ARG25) CRYSTAL STRUCTURE OF 3-DEHYDROQUINASE FROM SALMONELLA TYPHI COMPLEXED WITH REACTION PRODUCT | TIM-BARREL, COMPLEX WITH PRODUCT, LYASE
1l9w:D (MET1) to (ARG25) CRYSTAL STRUCTURE OF 3-DEHYDROQUINASE FROM SALMONELLA TYPHI COMPLEXED WITH REACTION PRODUCT | TIM-BARREL, COMPLEX WITH PRODUCT, LYASE
4oa7:B (SER1277) to (LYS1312) CRYSTAL STRUCTURE OF TANKYRASE1 IN COMPLEX WITH IWR1 | TANKYRASE, INHIBITOR, IWR1, TRANSFERASE
4obm:A (GLU144) to (ALA167) CRYSTAL STRUCTURE OF A PUTATIVE TRANSCRIPTION REGULATOR (EUBSIR_01389) FROM EUBACTERIUM SIRAEUM DSM 15702 AT 2.15 A RESOLUTION | PF03816 FAMILY, LYTR_CPSA_PSR, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, TRANSCRIPTION REGULATOR
2yvj:A (HIS90) to (LEU107) CRYSTAL STRUCTURE OF THE FERREDOXIN-FERREDOXIN REDUCTASE (BPHA3-BPHA4)COMPLEX | ELECTRON TRANSFER, FERREDOXIN, FERREDOXIN REDUCTASE, OXIDOREDUCTASE/ELECTRON TRANSPORT COMPLEX
2ywj:A (ASP109) to (VAL133) CRYSTAL STRUCTURE OF UNCHARACTERIZED CONSERVED PROTEIN FROM METHANOCALDOCOCCUS JANNASCHII | UNCHARACTERIZED CONSERVED PROTEIN, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
2nyz:A (LYS243) to (LEU281) VIRAL CHEMOKINE BINDING PROTEIN M3 FROM MURINE GAMMAHERPESVIRUS68 IN COMPLEX WITH THE C- CHEMOKINE XCL1 | VIRAL DECOY RECEPTOR, CHEMOKINE, PROTEIN-PROTEIN COMPLEX, VIRAL PROTEIN/CYTOKINE COMPLEX
2nz5:B (GLU302) to (SER320) STRUCTURE AND FUNCTION STUDIES OF CYTOCHROME P450 158A1 FROM STREPTOMYCES COELICOLOR A3(2) | STREPTOMYCES; CYTOCHROME P450 OXIDOREDUCTASE; CYP158A1; FLAVIOLIN; C- C COUPLING ACTIVITY, OXIDOREDUCTASE
2nza:B (GLU302) to (SER320) STRUCTURE AND FUNCTION STUDIES OF CYTOCHROME P450 158A1 FROM STREPTOMYCES COELICOLOR A3(2) | STREPTOMYCES; CYTOCHROME P450 OXIDOREDUCTASE; CYP158A1; FLAVIOLIN; C- C COUPLING ACTIVITY, OXIDOREDUCTASE
4ogm:A (THR1128) to (ASN1147) MBP-FUSION PROTEIN OF PILA1 RESIDUES 26-159 | TYPE IV PILIN, FIMBRIAL PROTEIN, CELL ADHESION
5clm:A (TYR342) to (PRO373) 1,4-OXAZINE BACE1 INHIBITORS | BACE1 PROTEASE INHIBITOR, ORALLY BIOAVAILABLE, BRAIN PENETRANT, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
2z49:B (ARG94) to (ILE122) CRYSTAL STRUCTURE OF HEMOLYTIC LECTIN CEL-III COMPLEXED WITH METHYL-ALPHA-D-GALACTOPYLANOSIDE | LECTIN, CEL-III, HEMOLYSIS, HEMAGGLUTINATION, PORE-FORMING, CALCIUM, MAGNESIUM, METHYL-ALPHA-D-GALACTOPYLANOSIDE, TOXIN
4oif:C (GLU658) to (ASP676) 3D STRUCTURE OF GAN42B, A GH42 BETA-GALACTOSIDASE FROM G. | BETA-GALACTOSIDASE. GAN42B, BETA-GALACTOSIDASE, GH42, GAN42B, HOMO- TRIMER, HYDOLASE, CARBOHYDRATE/SUGAR BINDING, INTRACELLULAR, HYDROLASE
1ln2:A (LEU117) to (GLN154) CRYSTAL STRUCTURE OF HUMAN PHOSPHATIDYLCHOLINE TRANSFER PROTEIN IN COMPLEX WITH DILINOLEOYLPHOSPHATIDYLCHOLINE (SELENO-MET PROTEIN) | START DOMAIN, LIPID BINDING PROTEIN
3k5c:B (TYR342) to (PRO373) HUMAN BACE-1 COMPLEX WITH NB-216 | ASPARTYL PROTEINASE; ALZHEIMER'S DISEASE, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, MEMBRANE, PROTEASE, TRANSMEMBRANE
3k5c:C (TYR342) to (PRO373) HUMAN BACE-1 COMPLEX WITH NB-216 | ASPARTYL PROTEINASE; ALZHEIMER'S DISEASE, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, MEMBRANE, PROTEASE, TRANSMEMBRANE
3k5f:A (TYR342) to (PRO373) HUMAN BACE-1 COMPLEX WITH AYH011 | ASPARTYL PROTEASE, ALZHEIMER'S DISEASE, STRUCTURE-BASED DESIGN, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, MEMBRANE, PROTEASE, TRANSMEMBRANE
3k5f:C (TYR342) to (PRO373) HUMAN BACE-1 COMPLEX WITH AYH011 | ASPARTYL PROTEASE, ALZHEIMER'S DISEASE, STRUCTURE-BASED DESIGN, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, MEMBRANE, PROTEASE, TRANSMEMBRANE
2o3o:I (VAL171) to (THR202) CRYSTAL STRUCTURE OF THE SENSOR HISTIDINE KINASE REGULATOR YYCI FROM BACILLUS SUBTITLIS | TWO-COMPONENT SYSTEM, SIGNALING PROTEIN
2o3o:J (VAL171) to (THR202) CRYSTAL STRUCTURE OF THE SENSOR HISTIDINE KINASE REGULATOR YYCI FROM BACILLUS SUBTITLIS | TWO-COMPONENT SYSTEM, SIGNALING PROTEIN
1lqw:B (VAL59) to (ASP87) CRYSTAL STRUCTURE OF S.AUREUS PEPTIDE DEFORMYLASE | PDF, PEPTIDE DEFORMYLASE, HYDROLASE
2z8i:A (GLY97) to (THR150) CRYSTAL STRUCTURE OF ESCHERICHIA COLI GAMMA-GLUTAMYLTRANSPEPTIDASE IN COMPLEX WITH AZASERINE | THR391 FORMED A COVALENT BOND WITH AZASERINE, ACYLTRANSFERASE, GLUTATHIONE BIOSYNTHESIS, TRANSFERASE, ZYMOGEN
2z8i:C (GLY97) to (THR150) CRYSTAL STRUCTURE OF ESCHERICHIA COLI GAMMA-GLUTAMYLTRANSPEPTIDASE IN COMPLEX WITH AZASERINE | THR391 FORMED A COVALENT BOND WITH AZASERINE, ACYLTRANSFERASE, GLUTATHIONE BIOSYNTHESIS, TRANSFERASE, ZYMOGEN
2z8j:A (GLY97) to (THR150) CRYSTAL STRUCTURE OF ESCHERICHIA COLI GAMMA-GLUTAMYLTRANSPEPTIDASE IN COMPLEX WITH AZASERINE PREPARED IN THE DARK | AZASERINE WITH A DIAZO GROUP, COVALENT BOND WITH THR391, ACYLTRANSFERASE, GLUTATHIONE BIOSYNTHESIS, TRANSFERASE, ZYMOGEN
2z8k:A (GLY97) to (THR150) CRYSTAL STRUCTURE OF ESCHERICHIA COLI GAMMA-GLUTAMYLTRANSPEPTIDASE IN COMPLEX WITH ACIVICIN | ACIVICIN FORMED A COVALENT BOND WITH THR391, ACYLTRANSFERASE, GLUTATHIONE BIOSYNTHESIS, TRANSFERASE, ZYMOGEN
2z8k:C (GLY97) to (THR150) CRYSTAL STRUCTURE OF ESCHERICHIA COLI GAMMA-GLUTAMYLTRANSPEPTIDASE IN COMPLEX WITH ACIVICIN | ACIVICIN FORMED A COVALENT BOND WITH THR391, ACYLTRANSFERASE, GLUTATHIONE BIOSYNTHESIS, TRANSFERASE, ZYMOGEN
4a6f:A (LEU497) to (VAL522) CRYSTAL STRUCTURE OF SLM1-PH DOMAIN IN COMPLEX WITH PHOSPHOSERINE | SIGNALING PROTEIN, POST TRANSLATIONAL MODIFICATION
4a6f:B (LEU497) to (VAL522) CRYSTAL STRUCTURE OF SLM1-PH DOMAIN IN COMPLEX WITH PHOSPHOSERINE | SIGNALING PROTEIN, POST TRANSLATIONAL MODIFICATION
4a6h:A (LEU497) to (VAL522) CRYSTAL STRUCTURE OF SLM1-PH DOMAIN IN COMPLEX WITH INOSITOL-4-PHOSPHATE | SIGNALING PROTEIN
4a6h:B (LEU497) to (VAL522) CRYSTAL STRUCTURE OF SLM1-PH DOMAIN IN COMPLEX WITH INOSITOL-4-PHOSPHATE | SIGNALING PROTEIN
4ojy:A (GLU658) to (ASP676) 3D STRUCTURE OF THE E323A CATALYTIC MUTANT OF GAN42B, A GH42 BETA- GALACTOSIDASE FROM G. STEAROTHERMOPHILUS | BETA-GALACTOSIDASE. GAN42B, BETA-GALACTOSIDASE, GH42, GAN42B, HOMO- TRIMER, HYDOLASE, CARBOHYDRATE/SUGAR BINDING, INTRACELLULAR, HYDROLASE
4ojy:B (GLU658) to (ASP676) 3D STRUCTURE OF THE E323A CATALYTIC MUTANT OF GAN42B, A GH42 BETA- GALACTOSIDASE FROM G. STEAROTHERMOPHILUS | BETA-GALACTOSIDASE. GAN42B, BETA-GALACTOSIDASE, GH42, GAN42B, HOMO- TRIMER, HYDOLASE, CARBOHYDRATE/SUGAR BINDING, INTRACELLULAR, HYDROLASE
2zbz:A (ALA301) to (ASN320) CRYSTAL STRUCTURE OF VITAMIN D HYDROXYLASE CYTOCHROME P450 105A1 (R84A MUTANT) IN COMPLEX WITH 1,25-DIHYDROXYVITAMIN D3 | P450, BETA PRISM, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE
1xn2:A (TYR342) to (PRO373) NEW SUBSTRATE BINDING POCKETS FOR BETA-SECRETASE. | BETA SECRETASE, MEMAPSIN2, BACE, ASP2, ASPARTIC PROTEASE, ALZHEIMER'S DISEASE, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1xn2:B (TYR342) to (PRO373) NEW SUBSTRATE BINDING POCKETS FOR BETA-SECRETASE. | BETA SECRETASE, MEMAPSIN2, BACE, ASP2, ASPARTIC PROTEASE, ALZHEIMER'S DISEASE, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1xn2:C (TYR342) to (PRO373) NEW SUBSTRATE BINDING POCKETS FOR BETA-SECRETASE. | BETA SECRETASE, MEMAPSIN2, BACE, ASP2, ASPARTIC PROTEASE, ALZHEIMER'S DISEASE, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1xn2:D (TYR342) to (PRO373) NEW SUBSTRATE BINDING POCKETS FOR BETA-SECRETASE. | BETA SECRETASE, MEMAPSIN2, BACE, ASP2, ASPARTIC PROTEASE, ALZHEIMER'S DISEASE, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1xn3:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SECRETASE BOUND TO A LONG INHIBITOR WITH ADDITIONAL UPSTREAM RESIDUES. | BACE, ALZHEIMER'S DISEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1xn3:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SECRETASE BOUND TO A LONG INHIBITOR WITH ADDITIONAL UPSTREAM RESIDUES. | BACE, ALZHEIMER'S DISEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1xn3:C (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SECRETASE BOUND TO A LONG INHIBITOR WITH ADDITIONAL UPSTREAM RESIDUES. | BACE, ALZHEIMER'S DISEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1xn3:D (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SECRETASE BOUND TO A LONG INHIBITOR WITH ADDITIONAL UPSTREAM RESIDUES. | BACE, ALZHEIMER'S DISEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2ze1:A (TYR404) to (PRO435) X-RAY STRUCTURE OF BACE-1 IN COMPLEX WITH COMPOUND 6G | BACE, ASPARTYL PROTEASE, ACYLGUANIDINE INHIBITOR, ALTERNATIVE SPLICING, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
1m27:C (ASP118) to (PRO140) CRYSTAL STRUCTURE OF SAP/FYNSH3/SLAM TERNARY COMPLEX | SH2-SH3 INTERACTION, SIGNALING PROTEIN, TRANSFERASE
2zgw:A (GLY45) to (SER67) CRYSTAL STRUCTURE OF BIOTIN PROTEIN LIGASE FROM PYROCOCCUS HORIKOSHII COMPLEXED WITH ADENOSINE AND BIOTIN, MUTATIONS R48A AND K111A | BIOTIN BIOSYNTHESIS, DIMER, LIGASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2zgw:B (MET44) to (SER67) CRYSTAL STRUCTURE OF BIOTIN PROTEIN LIGASE FROM PYROCOCCUS HORIKOSHII COMPLEXED WITH ADENOSINE AND BIOTIN, MUTATIONS R48A AND K111A | BIOTIN BIOSYNTHESIS, DIMER, LIGASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2zhr:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH OM99-2 AT PH 5.0 | OM99-2 COMPLEX, PH 5.0, ASPARTYL PROTEASE, GLYCOPROTEIN, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2zhs:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 AT PH 4.0 | PH 4.0, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3kcc:B (GLY45) to (GLY71) CRYSTAL STRUCTURE OF D138L MUTANT OF CATABOLITE GENE ACTIVATOR PROTEIN | HELIX-TURN-HELIX, ACTIVATOR, CAMP, CAMP-BINDING, DNA-BINDING, NUCLEOTIDE-BINDING, TRANSCRIPTION, TRANSCRIPTION REGULATION
3kd9:C (TYR89) to (PHE108) CRYSTAL STRUCTURE OF PYRIDINE NUCLEOTIDE DISULFIDE OXIDOREDUCTASE FROM PYROCOCCUS HORIKOSHII | PSI-II, NYSGXRC, OXIDOREDUCTASE, 11140O, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, FAD, FLAVOPROTEIN, NAD, REDOX-ACTIVE CENTER
2zjj:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF THE HUMAN BACE1 CATALYTIC DOMAIN IN COMPLEX WITH 4-(4-FLUORO-BENZYL)-PIPERAZINE-2-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)- AMIDE | BACE1, SMALL-MOLECULE INHIBITOR, TETHERING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
2zjn:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF THE HUMAN BACE1 CATALYTIC DOMAIN IN COMPLEX WITH N-[1-(5-CHLORO-2-ISOPROPOXY-3-METHOXY-BENZYL)- PIPERIDIN-4-YL]-2-(2-METHYL-4-SULFAMOYL-PHENOXY)-ACETAMIDE | BACE1, SMALL-MOLECULE INHIBITOR, FRAGMENT-BASED DISCOVERY, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
4op0:B (GLY244) to (LEU265) CRYSTAL STRUCTURE OF BIOTIN PROTEIN LIGASE (RV3279C) OF MYCOBACTERIUM TUBERCULOSIS, COMPLEXED WITH BIOTINYL-5'-AMP | BIRA, LIGASE
1m6i:A (ASN241) to (ILE258) CRYSTAL STRUCTURE OF APOPTOSIS INDUCING FACTOR (AIF) | APOPTOSIS, AIF, OXIDOREDUCTASE
4oqr:A (GLU293) to (ILE310) STRUCTURE OF A CYP105AS1 MUTANT IN COMPLEX WITH COMPACTIN | CYTOCHROME P450, MONOOXYGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4orf:A (GLY60) to (GLY85) CAMP-BINDING ACYLTRANSFERASE FROM MYCOBACTERIUM SMEGMATIS, MUTANT R95K | ALPHA-BETA FOLD, LINKER PEPTIDE, CYCLIC NUCLEOTIDE BINDING DOMAIN, ACYL-TRANSFERASE DOMAIN, TRANSFERASE
3kg2:D (ASN359) to (SER388) AMPA SUBTYPE IONOTROPIC GLUTAMATE RECEPTOR IN COMPLEX WITH COMPETITIVE ANTAGONIST ZK 200775 | ION CHANNEL, MEMBRANE PROTEIN, CELL MEMBRANE, GLYCOPROTEIN, ION TRANSPORT, MEMBRANE, POSTSYNAPTIC CELL MEMBRANE, RECEPTOR, RNA EDITING, SYNAPSE, TRANSMEMBRANE, TRANSPORT, TETRAMER, TRANSPORT PROTEIN
1mc7:A (GLY13) to (PRO47) SOLUTION STRUCTURE OF MDVL1 PDZ DOMAIN | PDZ DOMAIN, WNT SIGNALING, SIGNALING PROTEIN
4p16:A (ALA220) to (GLY248) CRYSTAL STRUCTURE OF THE PAPAIN-LIKE PROTEASE OF MIDDLE-EAST RESPIRATORY SYNDROME CORONAVIRUS | MERS-COV, PAPAIN-LIKE PROTEASE, DEUBIQUITINASE, HYDROLASE
4afs:C (ASP37) to (PRO59) HUMAN CHYMASE - FYNOMER COMPLEX | HYDROLASE-DE NOVO PROTEIN COMPLEX, INHIBITOR, SERINE PROTEASE
5d3m:A (ASP3) to (GLY40) FOLATE ECF TRANSPORTER: AMPPNP BOUND STATE | ECF TRANSPORTER, FOLATE, MEMBRANE PROTEIN, VITAMIN TRANSPORT, TRANSPORT PROTEIN
5d3m:E (ASP3) to (GLY40) FOLATE ECF TRANSPORTER: AMPPNP BOUND STATE | ECF TRANSPORTER, FOLATE, MEMBRANE PROTEIN, VITAMIN TRANSPORT, TRANSPORT PROTEIN
3kmx:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH346572 | ALZHEIMER'S, BACE1, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3kmx:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH346572 | ALZHEIMER'S, BACE1, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3kmy:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH12472 | BACE1, ALZHEIMER'S, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3kmy:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH12472 | BACE1, ALZHEIMER'S, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3kn0:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH708236 | BACE1, ALZHEIMER'S, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3kn0:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH708236 | BACE1, ALZHEIMER'S, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
1y8e:A (ILE184) to (CYS215) VCP:SURAMIN COMPLEX | BETA BARREL, VIRAL PROTEIN
5d6f:A (ASN329) to (GLU357) STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 COMPLEXED WITH SPIROEPOXYTRIAZOLE INHIBITOR (+)-31B | METAP2, METHIONINE AMINOPEPTIDASE-2, INHIBITOR, SPIROEPOXYTRIAZOLE, HYDROLASE
3a45:B (ARG97) to (PHE121) CRYSTAL STRUCTURE OF MVNEI1_2 | HELIX TWO TURNS HELIX, ZINC-LESS FINGER, HYDROLASE, DNA DAMAGE, DNA REPAIR, DNA-BINDING, GLYCOSIDASE, LYASE, MULTIFUNCTIONAL ENZYME
3a46:B (ALA98) to (PHE121) CRYSTAL STRUCTURE OF MVNEI1/THF COMPLEX | HELIX TWO TURNS HELIX, ZINC-LESS FINGER, HYDROLASE, THF, DNA DAMAGE, DNA REPAIR, DNA-BINDING, GLYCOSIDASE, LYASE, MULTIFUNCTIONAL ENZYME
4pa0:A (LYS58) to (PRO81) OMECAMTIV MERCARBIL BINDING SITE ON THE HUMAN BETA-CARDIAC MYOSIN MOTOR DOMAIN | CARDIAC, MYOSIN, MOTOR, OMECAMTIV MERCARBIL, MOTOR-FLUORESCENT PROTEIN COMPLEX
3a4h:A (GLU293) to (GLY311) STRUCTURE OF CYTOCHROME P450 VDH FROM PSEUDONOCARDIA AUTOTROPHICA (ORTHORHOMBIC CRYSTAL FORM) | CYTOCHROME P450, VITAMIN D3 HYDROXYLASE, HEMOPROTEIN, MONOOXYGENASE, OXIDOREDUCTASE
3a50:E (GLU293) to (LEU312) STRUCTURE OF CYTOCHROME P450 VDH MUTANT (VDH-K1) OBTAINED BY DIRECTED EVOLUTION WITH BOUND VITAMIN D3 | CYTOCHROME P450, VITAMIN D3 HYDROXYLASE, HEMOPROTEIN, MONOOXYGENASE, DIRECTED EVOLUTION, OXIDOREDUCTASE
5dah:A (LEU39) to (ARG94) CRYSTAL STRUCTURE OF PZP DOMAIN OF HUMAN AF10 PROTEIN FUSED WITH HISTONE H3 PEPTIDE | PHD FINGER, HISTONE TAIL READER, EPIGENETICS, H3K27 RECOGNITION, PEPTIDE BINDING PROTEIN
3kw4:A (ASP374) to (VAL391) CRYSTAL STRUCTURE OF CYTOCHROME 2B4 IN COMPLEX WITH THE ANTI-PLATELET DRUG TICLOPIDINE | P450, CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2, ENDOPLASMIC RETICULUM, HEME, IRON, MEMBRANE, METAL-BINDING, MICROSOME
1ym4:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE COMPLEXED WITH NVP-AMK640 | BETA-SECRETASE, MEMAPSIN2, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5dca:A (GLU2052) to (GLU2097) CRYSTAL STRUCTURE OF YEAST FULL LENGTH BRR2 IN COMPLEX WITH PRP8 JAB1 DOMAIN | PROTEIN COMPLEX, HELICASE, RNP REMODELING, SPLICEOSOME ACTIVATION, HYDROLASE
3abo:A (MET141) to (THR166) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND ETHANOLAMINE | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
3abo:C (MET141) to (THR166) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND ETHANOLAMINE | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
3abq:A (MET141) to (THR166) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND 2-AMINO-1-PROPANOL | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
3abq:C (MET141) to (THR166) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND 2-AMINO-1-PROPANOL | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
3kyr:A (TYR342) to (PRO373) BACE-1 IN COMPLEX WITH A NORSTATINE TYPE INHIBITOR | BACE, BETA-SECRETASE, MEMAPSIN-2, ASPARTYL PROTEASE, INHIBITOR, NORSTATINE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3kyr:C (TYR342) to (PRO373) BACE-1 IN COMPLEX WITH A NORSTATINE TYPE INHIBITOR | BACE, BETA-SECRETASE, MEMAPSIN-2, ASPARTYL PROTEASE, INHIBITOR, NORSTATINE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3abr:C (MET141) to (THR166) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL (SUBSTRATE-FREE FORM) | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
3abs:C (MET141) to (THR166) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH ADENINYLPENTYLCOBALAMIN AND ETHANOLAMINE | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN
5dfa:A (GLU658) to (ASP676) 3D STRUCTURE OF THE E323A CATALYTIC MUTANT OF GAN42B, A GH42 BETA- GALACTOSIDASE FROM G. STEAROTHERMOPHILUS | GLYCOSIDE HYDROLASE, GEOBACILLUS STEAROTHERMOPHILUS, MUTANT PROTEINS, BETA-GALACTOSIDASE, HYDROLASE
5dfa:B (GLU658) to (ASP676) 3D STRUCTURE OF THE E323A CATALYTIC MUTANT OF GAN42B, A GH42 BETA- GALACTOSIDASE FROM G. STEAROTHERMOPHILUS | GLYCOSIDE HYDROLASE, GEOBACILLUS STEAROTHERMOPHILUS, MUTANT PROTEINS, BETA-GALACTOSIDASE, HYDROLASE
4ph6:B (PRO3) to (ALA24) STRUCTURE OF 3-DEHYDROQUINATE DEHYDRATASE FROM ENTEROCOCCUS FAECALIS | (BETA/ALPHA)8 BARREL, LYASE
5dg6:A (ALA48) to (GLU75) 2.35A RESOLUTION STRUCTURE OF NOROVIRUS 3CL PROTEASE IN COMPLEX AN OXADIAZOLE-BASED, CELL PERMEABLE MACROCYCLIC (21-MER) INHIBITOR | PROTEASE, NOROVIRUS, NORWALK VIRUS, ANTIVIRAL INHIBITORS, OXADIAZOLE INHIBITOR, CELL PERMEABLE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3l2z:A (ARG245) to (HIS264) CRYSTAL STRUCTURE OF HYDRATED BIOTIN PROTEIN LIGASE FROM M. TUBERCULOSIS | BIRA, HYDRATED STRUCTURE, DISORDERED LIGAND BINDING LOOPS, LIGASE
1ys5:A (LYS120) to (HIS149) SOLUTION STRUCTURE OF THE ANTIGENIC DOMAIN OF GNA1870 OF NEISSERIA MENINGITIDIS | VACCINE CANDIDATE, NEISSERIA MENINGITIDIS, BETA-BARREL STRUCTURE, SIGNALING PROTEIN
3l58:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH589432 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3l5b:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH713601 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3l5b:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH713601 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3l5c:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH723871 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3l5c:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH723871 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3l5d:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH723873 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3l5d:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH723873 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3l5e:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH736062 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3l5e:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH736062 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3l5n:B (LYS1529) to (SER1551) STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) IN COMPLEX WITH HUMAN COMPLEMENT COMPONENT C3B | COMPLEMENT ALTERNATE PATHWAY, COMPLEMENT PATHWAY, CONVERSTASE, IMMUNE RESPONSE, INFLAMMATORY RESPONSE, INNATE IMMUNITY, SECRETED, VIRULENCE, IMMUNE EVASION, IMMUNE SYSTEM
4po6:A (LEU28) to (THR52) CRYSTAL STRUCTURE OF THE HUMAN TYK2 FERM AND SH2 DOMAINS WITH AN IFNAR1 INTRACELLULAR PEPTIDE | FERM, SH2, KINASE, RECEPTOR, CYTOKINE, INTRACELLULAR, TRANSFERASE
3aii:A (GLY420) to (PRO449) ARCHAEAL NON-DISCRIMINATING GLUTAMYL-TRNA SYNTHETASE FROM METHANOTHERMOBACTER THERMAUTOTROPHICUS | AMINO-ACYL TRNA SYNTHETASE, LIGASE
4ani:E (GLY157) to (LYS210) STRUCTURAL BASIS FOR THE INTERMOLECULAR COMMUNICATION BETWEEN DNAK AND GRPE IN THE DNAK CHAPERONE SYSTEM FROM GEOBACILLUS KAUSTOPHILUS HTA426 | CHAPERONE, CHAPERONE CYCLE, COMPLEMENTARY ASSAY
1zco:B (LYS10) to (ALA28) CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS 3-DEOXY-D-ARABINO- HEPTULOSONATE 7-PHOSPHATE SYNTHASE | ARABINO-HEPTULOSONATE, SYNTHASE, SHIKIMATE, DAHP, DAH7P, DAHPS, DAH7PS, LYASE
3anx:A (MET5) to (PRO31) CRYSTAL STRUCTURE OF TRIAMINE/AGMATINE AMINOPROPYLTRANSFERASE (SPEE) FROM THERMUS THERMOPHILUS, COMPLEXED WITH MTA | SPEE, SPERMINE SYNTHASE, SPERMIDINE SYNTHASE, POLYAMINE, SPERMIDINE BIOSYNTHESIS, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3any:A (MET141) to (THR166) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND (R)-2-AMINO-1-PROPANOL | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN, TIM BARREL
3any:C (MET141) to (THR166) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND (R)-2-AMINO-1-PROPANOL | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN, TIM BARREL
3lnk:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH743813 | ALZHEIMER'S, BACE1, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3lnk:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH743813 | ALZHEIMER'S, BACE1, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
5dzc:A (GLY212) to (GLY233) CRYSTAL STRUCTURE OF PVX_084705 IN COMPLEX WITH AMP-PNP | STRUCTURAL GENOMICS CONSORTIUM (SGC), KINASE, TRANSFERASE
3lpj:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH743641 | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE
3lpj:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH743641 | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE
3lpk:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH747123 | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE
3lpk:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH747123 | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE
4au0:A (GLY355) to (LYS395) HYPOCREA JECORINA CEL6A D221A MUTANT SOAKED WITH 6-CHLORO-4- METHYLUMBELLIFERYL-BETA-CELLOBIOSIDE | HYDROLASE, HYDROLASE(O-GLYCOSYL), GLYCOSIDASE, GLYCOSIDE HYDROLASE, GH6, CLMUFG2, CELLULASE, GLYCOPROTEIN, FLUOROGENIC SUBSTRATE
4au0:B (GLY355) to (LYS395) HYPOCREA JECORINA CEL6A D221A MUTANT SOAKED WITH 6-CHLORO-4- METHYLUMBELLIFERYL-BETA-CELLOBIOSIDE | HYDROLASE, HYDROLASE(O-GLYCOSYL), GLYCOSIDASE, GLYCOSIDE HYDROLASE, GH6, CLMUFG2, CELLULASE, GLYCOPROTEIN, FLUOROGENIC SUBSTRATE
4q46:B (GLN323) to (ASP343) THE SECOND STRUCTURE OF INFLUENZA B PB2 CAP-BINDING DOMAIN COMPLEX WITH GDP | CAP BINDING, VIRAL PROTEIN
5e0h:B (ALA48) to (GLU74) 1.95 A RESOLUTION STRUCTURE OF NOROVIRUS 3CL PROTEASE IN COMPLEX WITH A TRIAZOLE-BASED MACROCYCLIC (18-MER) INHIBITOR | PROTEASE, NOROVIRUS, NORWALK VIRUS, ANTIVIRAL INHIBITORS, TRIAZOLE MACROCYCLIC INHIBITOR, CELL PERMEABLE, PROTEASE-PROTEASE INHIBITOR COMPLEX
4aui:B (GLY195) to (ASN220) STRUCTURE AND FUNCTION OF THE PORB PORIN FROM DISSEMINATING N. GONORRHOEAE | MEMBRANE PROTEIN, OUTER MEMBRANE PROTEIN, INFECTION, INVASION
4aui:C (GLY195) to (ASN220) STRUCTURE AND FUNCTION OF THE PORB PORIN FROM DISSEMINATING N. GONORRHOEAE | MEMBRANE PROTEIN, OUTER MEMBRANE PROTEIN, INFECTION, INVASION
1zsv:B (SER2) to (GLU40) CRYSTAL STRUCTURE OF HUMAN NADP-DEPENDENT LEUKOTRIENE B4 12- HYDROXYDEHYDROGENASE | MEDIUM-CHAIN DEHYDROGENASE/REDUCTASE FAMILY ,LEUKOTRIENE B4, HUMAN, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE
1zsv:D (SER2) to (GLU40) CRYSTAL STRUCTURE OF HUMAN NADP-DEPENDENT LEUKOTRIENE B4 12- HYDROXYDEHYDROGENASE | MEDIUM-CHAIN DEHYDROGENASE/REDUCTASE FAMILY ,LEUKOTRIENE B4, HUMAN, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE
5e1l:A (PRO143) to (MET161) STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE E. COLI FTSZ INTERACTING PROTEIN, ZAPC, REVEALS INSIGHT INTO MOLECULAR PROPERTIES OF A NOVEL Z RING STABILIZING PROTEIN | Z RING, CELL DIVISION, CELL CYCLE
3aq3:B (VAL39) to (TYR66) MOLECULAR INSIGHTS INTO PLANT CELL PROLIFERATION DISTURBANCE BY AGROBACTERIUM PROTEIN 6B | AGROBACTERIUM 6B, TOXIN, ADP-RIBOSYLATION, MIRNA MACHINERIES
3aqj:A (ALA22) to (VAL44) CRYSTAL STRUCTURE OF A C-TERMINAL DOMAIN OF THE BACTERIOPHAGE P2 TAIL SPIKE PROTEIN, GPV | BACTERIOPHAGE, TAIL SPIKE, IRON BINDING, BETA-HELIX, INFECTION, METAL BINDING PROTEIN
3aqj:R (LEU23) to (VAL44) CRYSTAL STRUCTURE OF A C-TERMINAL DOMAIN OF THE BACTERIOPHAGE P2 TAIL SPIKE PROTEIN, GPV | BACTERIOPHAGE, TAIL SPIKE, IRON BINDING, BETA-HELIX, INFECTION, METAL BINDING PROTEIN
4av5:A (PHE1) to (SER17) STRUCTURE OF A TRICLINIC CRYSTAL OF THE FIMH LECTIN DOMAIN IN COMPLEX WITH A PROPYNYL BIPHENYL ALPHA-D-MANNOSIDE, AT 1.4 A RESOLUTION | CELL ADHESION, BACTERIAL ADHESIN TYPE 1 FIMBRIAE, URINARY TRACT INFECTION, VARIABLE IMMUNOGLOBULIN FOLD
4aw3:A (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG F286V MUTANT IN COMPLEX WITH MYCINAMICIN V IN P1 SPACE GROUP | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
4aw3:B (GLU292) to (SER310) STRUCTURE OF THE MIXED-FUNCTION P450 MYCG F286V MUTANT IN COMPLEX WITH MYCINAMICIN V IN P1 SPACE GROUP | OXIDOREDUCTASE, MYCINAMICIN BIOSYNTHESIS
4ax6:A (GLY355) to (LYS395) HYPOCREA JECORINA CEL6A D221A MUTANT SOAKED WITH 6-CHLORO-4-PHENYLUMBELLIFERYL-BETA-CELLOBIOSIDE | HYDROLASE, HYDROLASE(O-GLYCOSYL), GLYCOSIDASE, GLYCOSIDE HYDROLASE, GH6, CLPHUFG2, CELLULASE, CELLOBIOHYDROLASE, GLYCOPROTEIN, FLUOROGENIC SUBSTRATE
4ax6:B (GLY355) to (LYS395) HYPOCREA JECORINA CEL6A D221A MUTANT SOAKED WITH 6-CHLORO-4-PHENYLUMBELLIFERYL-BETA-CELLOBIOSIDE | HYDROLASE, HYDROLASE(O-GLYCOSYL), GLYCOSIDASE, GLYCOSIDE HYDROLASE, GH6, CLPHUFG2, CELLULASE, CELLOBIOHYDROLASE, GLYCOPROTEIN, FLUOROGENIC SUBSTRATE
5e51:B (SER168) to (LEU192) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 1 WITH FAROPENEM ADDUCT | L, D-TRANSPEPTIDASE 1, PEPTIDOGLYCAN SYNTHESIS ENZYME, CELL WALL ENZYME, LDTMT1, MYCOBACTERIUM TUBERCULOSIS, TRANSFERASE
4ax7:A (GLY355) to (LYS395) HYPOCREA JECORINA CEL6A D221A MUTANT SOAKED WITH 4-METHYLUMBELLIFERYL-BETA-D-CELLOBIOSIDE | HYDROLASE, HYDROLASE(O-GLYCOSYL), GLYCOSIDASE, GLYCOSIDE HYDROLASE, GH6, MUFG2, CELLULASE, GLYCOPROTEIN, FLUOROGENIC SUBSTRATE
4ax7:B (GLY355) to (LYS395) HYPOCREA JECORINA CEL6A D221A MUTANT SOAKED WITH 4-METHYLUMBELLIFERYL-BETA-D-CELLOBIOSIDE | HYDROLASE, HYDROLASE(O-GLYCOSYL), GLYCOSIDASE, GLYCOSIDE HYDROLASE, GH6, MUFG2, CELLULASE, GLYCOPROTEIN, FLUOROGENIC SUBSTRATE
4ax7:C (GLY355) to (LYS395) HYPOCREA JECORINA CEL6A D221A MUTANT SOAKED WITH 4-METHYLUMBELLIFERYL-BETA-D-CELLOBIOSIDE | HYDROLASE, HYDROLASE(O-GLYCOSYL), GLYCOSIDASE, GLYCOSIDE HYDROLASE, GH6, MUFG2, CELLULASE, GLYCOPROTEIN, FLUOROGENIC SUBSTRATE
4ax7:D (GLY355) to (LYS395) HYPOCREA JECORINA CEL6A D221A MUTANT SOAKED WITH 4-METHYLUMBELLIFERYL-BETA-D-CELLOBIOSIDE | HYDROLASE, HYDROLASE(O-GLYCOSYL), GLYCOSIDASE, GLYCOSIDE HYDROLASE, GH6, MUFG2, CELLULASE, GLYCOPROTEIN, FLUOROGENIC SUBSTRATE
4q6u:B (LEU6) to (LYS26) CRYSTAL STRUCTURE OF A PUTATIVE UNCHARACTERIZED PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS | SEATTLE STRUCTURAL GENOICS FOR INFECTIOUS DISEASE, MYCOBACTERIUM TUBERCULOSIS, STRUCTURAL GENOMICS, SSGCID, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, UNKNOWN FUNCTION
5e5c:A (SER428) to (PRO447) CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINASE FROM PSEUDOMONAS AERUGINOSA PAO1 | DIHYDROPYRIMIDINASE, HYDROLASE
5e5c:C (SER428) to (PRO447) CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINASE FROM PSEUDOMONAS AERUGINOSA PAO1 | DIHYDROPYRIMIDINASE, HYDROLASE
3lwk:A (SER105) to (SER128) CRYSTAL STRUCTURE OF HUMAN BETA-CRYSTALLIN A4 (CRYBA4) | STRUCTURAL PROTEIN, BETA-CRYSTALLIN, STRUCTURAL GENOMICS CONSORTIUM, SGC, CATARACT, DISEASE MUTATION, EYE LENS PROTEIN, MICROPHTHALMIA, OXIDATION, PHOSPHOPROTEIN
5e7g:A (TYR345) to (ASN376) CRYSTAL STRUCTURE OF BACOVA_02650 WITH XYLOGLUCO-OLIGOSACCHARIDE | CARBOHYDRATE-BINDING PROTEIN, SUGAR BINDING PROTEIN
4b0q:A (TYR342) to (PRO373) LEAD GENERATION OF BACE1 INHIBITORS BY COUPLING NON-AMIDINE NEW WARHEADS TO A KNOWN BINDING SCAFFOLD | HYDROLASE, BACE1 INHIBITORS, LEAD GENERATION, STRUCTURE-BASED DRUG DESIGN
4qb5:D (TYR38) to (GLN71) CRYSTAL STRUCTURE OF A GLYOXALASE/BLEOMYCIN RESISTANCE PROTEIN FROM ALBIDIFERAX FERRIREDUCENS T118 | STRUCTURAL GENOMICS, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, PROTEIN STRUCTURE INITIATIVE, ALPHA/BETA, OXIDOREDUCTASE
5ec7:B (ASP91) to (ILE110) CRYSTAL STRUCTURE OF A CHIMERIC C-SRC-SH3 DOMAIN WITH THE SEQUENCE OF THE RT-LOOP FROM THE ABL-SH3 DOMAIN AT PH 5.0 | BETA SHANDWICH, TRANSFERASE
5ece:D (SER1277) to (LYS1312) TANKYRASE 1 WITH PHTHALAZINONE 1 | TANKYRASE, INHIBITOR, PARP, CENTROSOME CLUSTERING, ONCOLOGY, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3azo:A (GLU390) to (PRO419) CRYSTAL STRUCTURE OF PUROMYCIN HYDROLASE | POP FAMILY, HYDROLASE
4qfp:B (PRO499) to (LYS535) CRYSTAL STRUCTURE OF DIPEPTIDE BINDING PROTEIN FROM PSEUDOALTEROMONAS SP. SM9913 IN COMPLEX WITH VAL-THR | DIPEPTIDE BINDING PROTEIN, PEPTIDE BINDING PROTEIN
4b7d:B (PRO301) to (LEU319) PIKC BOUND TO THE 10-DML ANALOG WITH THE 3-(N,N-DIMETHYLAMINO) PROPANOATE ANCHORING GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
2a73:B (VAL1528) to (GLY1550) HUMAN COMPLEMENT COMPONENT C3 | INTACT THIOESTER, IMMUNE SYSTEM
3m7w:A (LYS2) to (THR26) CRYSTAL STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE (AROD) FROM SALMONELLA TYPHIMURIUM LT2 IN COVALENT COMPLEX WITH DEHYDROQUINATE | TYPE I 3-DEHYDROQUINASE, DHQASE_I, DEHYDROQUINATE, IDP90922, AMINO- ACID BIOSYNTHESIS, AROMATIC AMINO ACID BIOSYNTHESIS, LYASE, SCHIFF BASE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
3m7w:B (LYS2) to (LYS25) CRYSTAL STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE (AROD) FROM SALMONELLA TYPHIMURIUM LT2 IN COVALENT COMPLEX WITH DEHYDROQUINATE | TYPE I 3-DEHYDROQUINASE, DHQASE_I, DEHYDROQUINATE, IDP90922, AMINO- ACID BIOSYNTHESIS, AROMATIC AMINO ACID BIOSYNTHESIS, LYASE, SCHIFF BASE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
3m7w:D (MET1) to (THR26) CRYSTAL STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE (AROD) FROM SALMONELLA TYPHIMURIUM LT2 IN COVALENT COMPLEX WITH DEHYDROQUINATE | TYPE I 3-DEHYDROQUINASE, DHQASE_I, DEHYDROQUINATE, IDP90922, AMINO- ACID BIOSYNTHESIS, AROMATIC AMINO ACID BIOSYNTHESIS, LYASE, SCHIFF BASE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
4qi7:B (SER134) to (PHE159) CELLOBIOSE DEHYDROGENASE FROM NEUROSPORA CRASSA, NCCDH | IMMUNOGLOBULIN-LIKE BETA-SANDWICH (CYTOCHROME), FAD/NAD(P)-BINDING DOMAIN (DEHYDROGENASE DOMAIN), CELLOBIOSE OXIDIZING, ELECTRON TRANSFER, LIGNOCELLULOSE DEGRADATION, CELLOBIOSE, LPMO, OXIDOREDUCTASE
3m9z:A (ASP187) to (TYR215) CRYSTAL STRUCTURE OF EXTRACELLULAR DOMAIN OF MOUSE NKR-P1A | C-TYPE LECTIN-LIKE DOMAIN, DOMAIN SWAPPING, DISULFIDE BOND, RECEPTOR, TRANSMEMBRANE PROTEIN, NATURAL KILLER CELL RECEPTOR, SIGNALING PROTEIN
2abw:B (PHE131) to (GLU160) GLUTAMINASE SUBUNIT OF THE PLASMODIAL PLP SYNTHASE (VITAMIN B6 BIOSYNTHESIS) | GLUTAMINASE, PLP-SYNTHASE, VITAMIN B6, MALARIA, TRANSFERASE
4qiw:B (ARG441) to (THR490) CRYSTAL STRUCTURE OF EURYARCHAEAL RNA POLYMERASE FROM THERMOCOCCUS KODAKARENSIS | TRANSCRIPTION, DNA-DIRECTED RNA POLYMERASE
4qk0:D (LYS574) to (LYS616) CRYSTAL STRUCTURE OF ARA127N-SE, A GH127 BETA-L-ARABINOFURANOSIDASE FROM GEOBACILLUS STEAROTHERMOPHILUS T6 | GLYCOSIDE HYDROLASE, HYDROLASE
3mcy:A (PHE1) to (ASN23) CRYSTAL STRUCTURE OF FIMH LECTIN DOMAIN BOUND TO BIPHENYL MANNOSIDE META-METHYL ESTER. | LECTIN, MANNOSIDE, IMMUNOGOBULIN FOLD, CARBOHYDRATE BINDING PROTEIN
3mcy:D (PHE1) to (ASN23) CRYSTAL STRUCTURE OF FIMH LECTIN DOMAIN BOUND TO BIPHENYL MANNOSIDE META-METHYL ESTER. | LECTIN, MANNOSIDE, IMMUNOGOBULIN FOLD, CARBOHYDRATE BINDING PROTEIN
3me6:A (LYS373) to (VAL391) CRYSTAL STRUCTURE OF CYTOCHROME 2B4 IN COMPLEX WITH THE ANTI-PLATELET DRUG CLOPIDOGREL | P450, CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2
3me6:C (LYS373) to (VAL391) CRYSTAL STRUCTURE OF CYTOCHROME 2B4 IN COMPLEX WITH THE ANTI-PLATELET DRUG CLOPIDOGREL | P450, CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2
3mh7:A (ALA374) to (GLY404) HTRA PROTEASES ARE ACTIVATED BY A CONSERVED MECHANISM THAT CAN BE TRIGGERED BY DISTINCT MOLECULAR CUES | DEGP, HTRA, PROTEASE, OUTER MEMBRANE PROTEIN, HYDROLASE
3mhj:B (SER1124) to (ARG1159) HUMAN TANKYRASE 2 - CATALYTIC PARP DOMAIN IN COMPLEX WITH 1-METHYL-3- (TRIFLUOROMETHYL)-5H-BENZO[C][1,8]NAPHTYRIDINE-6-ONE | CATALYTIC FRAGMENT, PARP, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, ADP-RIBOSYLATION, ANK REPEAT, CHROMOSOMAL PROTEIN, GLYCOSYLTRANSFERASE, GOLGI APPARATUS, MEMBRANE, MRNA TRANSPORT, NAD, NUCLEUS, PHOSPHORYLATION, PROTEIN TRANSPORT, TELOMERE, TRANSFERASE, TRANSLOCATION, TRANSPORT, WNT-SIGNALLING
3mif:A (HIS108) to (GLY159) OXIDIZED (CU2+) PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE (PHM) WITH BOUND CARBON MONOOXIDE (CO) | OXIDOREDUCTASE, MONOOXYGENASE, BIOACTIVE PEPTIDE ACTIVATION, ASCORBATE
5enk:A (TYR390) to (PRO421) COMPOUND 18 | BACE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5enm:A (TYR390) to (PRO421) COMPOUND 10 | BACE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3mkr:B (PRO1165) to (CYS1185) CRYSTAL STRUCTURE OF YEAST ALPHA/EPSILON-COP SUBCOMPLEX OF THE COPI VESICULAR COAT | TETRATRICOPEPTIDE REPEATS (TPR), BETA-HAIRPIN, ALPHA-SOLENOID, TRANSPORT PROTEIN
4bel:A (TYR354) to (SER383) BACE2 XAPERONE COMPLEX | HYDROLASE-IMMUNE SYSTEM COMPLEX, NANOBODY
4bel:B (TYR354) to (SER383) BACE2 XAPERONE COMPLEX | HYDROLASE-IMMUNE SYSTEM COMPLEX, NANOBODY
3mkv:A (ASP377) to (LEU413) CRYSTAL STRUCTURE OF AMIDOHYDROLASE EAJ56179 | SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, PROLIDASE, HYDROLASE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3mkv:B (ASP377) to (LEU413) CRYSTAL STRUCTURE OF AMIDOHYDROLASE EAJ56179 | SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, PROLIDASE, HYDROLASE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3mkv:E (ASP377) to (LEU413) CRYSTAL STRUCTURE OF AMIDOHYDROLASE EAJ56179 | SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, PROLIDASE, HYDROLASE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3mkv:F (ASP377) to (LEU413) CRYSTAL STRUCTURE OF AMIDOHYDROLASE EAJ56179 | SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, PROLIDASE, HYDROLASE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
4bf4:D (GLU300) to (VAL317) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
4bf4:F (GLU300) to (LEU319) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
4bf4:G (PRO301) to (LEU319) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
4bf4:H (GLU300) to (VAL317) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
4bf4:I (GLU300) to (LEU319) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
4bf4:J (GLU300) to (VAL317) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
4bf4:K (GLU300) to (VAL318) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
4bf4:L (GLU300) to (LEU319) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
4bf4:M (GLU300) to (VAL317) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
4bf4:N (PRO301) to (VAL318) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED CYCLOALKANE SUBSTRATE MIMIC BEARING A TERMIANL N,N-DIMETHYLAMINO GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
4bfb:A (TYR354) to (SER383) BACE2 XAPERONE COMPLEX | HYDROLASE-IMMUNE SYSTEM COMPLEX, NANOBODY
4bfb:B (TYR354) to (SER383) BACE2 XAPERONE COMPLEX | HYDROLASE-IMMUNE SYSTEM COMPLEX, NANOBODY
4bfp:A (SER1124) to (PRO1149) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH WIKI4 | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP-RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5ety:C (SER1277) to (LYS1312) CRYSTAL STRUCTURE OF HUMAN TANKYRASE-1 BOUND TO K-756 | TANKYRASE, INHIBITOR, NON-COMPETITIVE, WNT SIGNAL, TRANSFERASE
5ety:D (SER1277) to (LYS1312) CRYSTAL STRUCTURE OF HUMAN TANKYRASE-1 BOUND TO K-756 | TANKYRASE, INHIBITOR, NON-COMPETITIVE, WNT SIGNAL, TRANSFERASE
4bjb:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH PJ-34 | TRANSFERASE, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, INHIBITOR
4bjc:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH RUCAPARIB | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE INHIBITOR COMPLEX
4bk5:C (LEU124) to (PRO148) CRYSTAL STRUCTURE OF THE HUMAN EPHA4 ECTODOMAIN IN COMPLEX WITH HUMAN EPHRIN A5 (AMINE-METHYLATED SAMPLE) | SIGNALING PROTEIN, CELL ADHESION, CELL REPULSION, RECEPTOR CLUSTERING, RECEPTOR CIS INTERACTION, ERYTHROPOETIN-PRODUCING HEPATOCELLULAR RECEPTOR, LBD, EGF, FN
4bka:C (LEU124) to (PRO148) CRYSTAL STRUCTURE OF THE HUMAN EPHA4 ECTODOMAIN IN COMPLEX WITH HUMAN EPHRIN A5 | CELL ADHESION, CELL REPULSION, RECEPTOR CLUSTERING, RECEPTOR CIS INTERACTION, EPH-EPHRIN, EPH ECTODOMAIN, ERYTHROPOETIN-PRODUCING HEPATOCELLULAR RECEPTOR, LBD, SUSHI, EGF, FN
3msj:A (TYR342) to (PRO373) STRUCTURE OF BACE (BETA SECRETASE) IN COMPLEX WITH INHIBITOR | PROTEASE, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, AMYLOID PRECURSOR PROTEIN SECRETASES, ASPARTIC ENDOPEPTIDASES, FRAGMENT- BASED DRUG DESIGN, FLUORESCENCE POLARISATION, TRANSMEMBRANE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3msj:B (TYR342) to (PRO373) STRUCTURE OF BACE (BETA SECRETASE) IN COMPLEX WITH INHIBITOR | PROTEASE, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, AMYLOID PRECURSOR PROTEIN SECRETASES, ASPARTIC ENDOPEPTIDASES, FRAGMENT- BASED DRUG DESIGN, FLUORESCENCE POLARISATION, TRANSMEMBRANE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3msj:C (TYR342) to (PRO373) STRUCTURE OF BACE (BETA SECRETASE) IN COMPLEX WITH INHIBITOR | PROTEASE, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, AMYLOID PRECURSOR PROTEIN SECRETASES, ASPARTIC ENDOPEPTIDASES, FRAGMENT- BASED DRUG DESIGN, FLUORESCENCE POLARISATION, TRANSMEMBRANE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5ewo:A (ALA520) to (ASN550) CRYSTAL STRUCTURE OF THE HUMAN ASTROVIRUS 1 CAPSID PROTEIN SPIKE DOMAIN AT 0.95-A RESOLUTION | VIRAL PROTEIN, CAPSID PROTEIN, ICOSAHEDRAL VIRUS, BETA BARREL
3msl:A (TYR342) to (PRO373) FRAGMENT BASED DISCOVERY AND OPTIMISATION OF BACE-1 INHIBITORS | PROTEASE, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, AMYLOID PRECURSOR PROTEIN SECRETASES, ASPARTIC ENDOPEPTIDASES, FRAGMENT- BASED DRUG DESIGN, FLUORESCENCE POLARISATION, TRANSMEMBRANE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4blo:G (GLY253) to (PHE275) P4 PROTEIN FROM BACTERIOPHAGE PHI6 IN COMPLEX WITH ADP | HYDROLASE, ATPASE, CYSTOVIRIDAE
5f01:A (TYR403) to (PRO434) CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH (1SR,2SR)-2-((R)-2-AMINO- 5,5-DIFLUORO-4-METHYL-5,6-DIHYDRO-4H-1,3-OXAZIN-4-YL)-N-(3- CHLOROQUINOLIN-8-YL)CYCLOPROPANECARBOXAMIDE | PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, HYDROLASE
3bof:A (ALA302) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM THERMOTOGA MARITIMA COMPLEXED WITH ZN2+ AND HOMOCYSTEINE | METH, TRANSFERASE, TIM BARREL, HOMOCYSTEINE, ZINC, ZINC INVERSION, METHYLTRANSFERASE
3bof:B (ALA302) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM THERMOTOGA MARITIMA COMPLEXED WITH ZN2+ AND HOMOCYSTEINE | METH, TRANSFERASE, TIM BARREL, HOMOCYSTEINE, ZINC, ZINC INVERSION, METHYLTRANSFERASE
3bol:A (PHE301) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM THERMOTOGA MARITIMA COMPLEXED WITH ZN2+ | METH, TRANSFERASE, TIM BARREL, ZINC, ZINC INVERSION, METHYLTRANSFERASE
3bol:B (ALA302) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (1-566) FROM THERMOTOGA MARITIMA COMPLEXED WITH ZN2+ | METH, TRANSFERASE, TIM BARREL, ZINC, ZINC INVERSION, METHYLTRANSFERASE
3mvr:A (ASP374) to (VAL391) CRYSTAL STRUCTURE OF CYTOCHROME P450 2B4-H226Y IN A CLOSED CONFORMATION | LIGAND FREE CLOSED CONFORMATION, P450, CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4.
3bug:A (TYR342) to (PRO373) BACE-1 COMPLEXED WITH COMPOUND 3 | ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, BETA-SECRETASE, MEMAPSIN 2, FRAGMENT SCREEN, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
3mzs:A (SER361) to (ALA379) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP11A1 IN COMPLEX WITH 22- HYDROXY-CHOLESTEROL | CYP11A1, CYTOCHROME P450, MONOOXYGENASE, SIDE CHAIN CLEAVAGE ENZYME, CHOLESTEROL, CHOLESTEROL 20-22-DESMOLASE, STEROID METABOLISM, OXIDOREDUCTASE, HEME
3mzs:D (LEU363) to (ALA379) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP11A1 IN COMPLEX WITH 22- HYDROXY-CHOLESTEROL | CYP11A1, CYTOCHROME P450, MONOOXYGENASE, SIDE CHAIN CLEAVAGE ENZYME, CHOLESTEROL, CHOLESTEROL 20-22-DESMOLASE, STEROID METABOLISM, OXIDOREDUCTASE, HEME
4bs4:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 4'-ISOPROPYLFLAVONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4bsr:A (CYS38) to (PHE67) STRUCTURE OF THE ECTODOMAIN OF LGR5 IN COMPLEX WITH R-SPONDIN-1 (FU1FU2) IN P22121 CRYSTAL FORM | SIGNALING PROTEIN, ADULT STEM CELL, LEUCINE-RICH REPEAT G-PROTEIN COUPLED RECEPTOR, LEUCINE-RICH REPEAT, FURIN DOMAIN, WNT SIGNALING, CONGENITAL ANONYCHIA
4bt2:A (GLY192) to (ASP214) ACETOLACTATE DECARBOXYLASE WITH A BOUND 1,2-ETHANEDIOL | LYASE, ACETOIN BIOSYNTHESIS, STEREOSELECTIVE DECARBOXYLATION, BIFUNCTIONAL ENZYME
4bt6:A (GLY192) to (ASP214) ACETOLACTATE DECARBOXYLASE WITH A BOUND GLYCEROL | LYASE, ACETOIN BIOSYNTHESIS, STEREOSELECTIVE DECARBOXYLATION, BIFUNCTIONAL ENZYME
4bu3:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 2-PHENYL-3,4-DIHYDROQUINAZOLIN-4-ONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4bu5:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 2-(4- HYDROXYPHENYL)-3,4-DIHYDROQUINAZOLIN-4-ONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4bud:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 2-(4- TERT-BUTYLPHENYL)-1,4-DIHYDROQUINAZOLIN-4-ONE | TRANSFERASE, DIPHTHERIA TOXIN LIKE FOLD, ADP-RIBOSYLATION, INHIBITOR
4bu9:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 2-(4- METHOXYPHENYL)-3,4-DIHYDROQUINAZOLIN-4-ONE | TRANSFERASE, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4bua:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 2-(4- (METHYLSULFANYL)PHENYL)-3,4-DIHYDROQUINAZOLIN-4-ONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4bue:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 3-METHYL- N-(4-(4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)PHENYL)BUTANAMIDE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4bui:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH METHYL 4-(4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)BENZOATE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP-RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5fbh:B (HIS466) to (SER497) CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CALCIUM SENSING RECEPTOR WITH BOUND GD3+ | MEMBRANE PROTEIN, G-PROTEIN COUPLED RECEPTOR, SIGNALING PROTEIN
5fbh:A (HIS466) to (SER497) CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CALCIUM SENSING RECEPTOR WITH BOUND GD3+ | MEMBRANE PROTEIN, G-PROTEIN COUPLED RECEPTOR, SIGNALING PROTEIN
5fbk:A (HIS466) to (SER497) CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CALCIUM SENSING RECEPTOR | MEMBRANE PROTEIN, G-PROTEIN COUPLED RECEPTOR, ECTODOMAIN, SIGNALING PROTEIN
5fbk:B (HIS466) to (SER497) CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CALCIUM SENSING RECEPTOR | MEMBRANE PROTEIN, G-PROTEIN COUPLED RECEPTOR, ECTODOMAIN, SIGNALING PROTEIN
4buq:A (PHE1) to (ASN23) CRYSTAL STRUCTURE OF WILD TYPE FIMH LECTIN DOMAIN IN COMPLEX WITH HEPTYL ALPHA-D-MANNOPYRANNOSIDE | CELL ADHESION, TYPE 1 FIMBRIAE, URINARY TRACT INFECTION, VARIABLE IMMUNOGLOBULIN FOLD
4but:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 4-(4- OXO-3,4-DIHYDROQUINAZOLIN-2-YL)BENZENE-1-SULFONAMIDE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4buu:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH (4- (4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)PHENYL)METHANESULFONAMIDE | TRANSFERASE, DIPHTHERIA TOXIN LIKE FOLD, ADP-RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4buv:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH N-(4- (4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)PHENYL)THIOPHENE-2-CARBOXAMIDE | TRANSFERASE, DIPHTHERIA TOXIN LIKE FOLD, ADP-RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4buw:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 2-(4- (2-OXO-1,3-OXAZOLIDIN-3-YL)PHENYL)-3,4- DIHYDROQUINAZOLIN-4-ONE | TRANSFERASE, DIPHTHERIA TOXIN LIKE FOLD, ADP-RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4buy:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 5- METHYL-5-(4-(4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)PHENYL) IMIDAZOLIDINE-2,4-DIONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP-RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4bv4:L (ARG11) to (CYS68) STRUCTURE AND ALLOSTERY IN TOLL-SPATZLE RECOGNITION | CYTOKINE RECOGNITION, EMBRYONIC DEVELOPMENT, IMMUNE SYSTEM, INNATE IMMUNITY, LEUCINE-RICH REPEATS, CYSTINE-KNOT, GLYCOPROTEIN
4r21:A (ASP378) to (ASN395) ZEBRA FISH CYTOCHROME P450 17A2 WITH PROGESTERONE | CYTOCHROME P450 17A2, PROGESTERONE, P450 17A2, 17 (ALPHA)- HYDROXYLATION, STEROID BIOSYNTHESIS, ENZYME KINETICS, OXIDOREDUCTASE
3c7u:B (SER108) to (SER139) STRUCTURAL INSIGHT INTO THE KINETICS AND CP OF INTERACTIONS BETWEEN TEM-1-LACTAMASE AND BLIP | ENZYME-INHIBITOR COMPLEX, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, SECRETED, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3c7v:B (SER108) to (SER139) STRUCTURAL INSIGHT INTO THE KINETICS AND DELTA-CP OF INTERACTIONS BETWEEN TEM-1 BETA-LACTAMASE AND BLIP | ENZYME-INHIBITOR COMPLEX, ANTIBIOTIC RESISTANCE, HYDROLASE, PLASMID, SECRETED, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3c8o:A (VAL129) to (ASP147) THE CRYSTAL STRUCTURE OF RRAA FROM PAO1 | RRAA, PAO1, RNASE E REGULATER, HYDROLASE REGULATOR
5fil:H (LEU62) to (ASN85) BOVINE MITOCHONDRIAL ATP SYNTHASE STATE 3B | ATP SYNTHASE, ROTARY ATPASE
3na1:A (ASN361) to (VAL378) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH 20- HYDROXYCHOLESTEROL | CYTOCHROME P450, 20-HYDROXYCHOLESTEROL, CHOLESTEROL SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
4c0g:C (SER695) to (ASP717) STRUCTURE OF THE NOT-BOX DOMAIN OF HUMAN CNOT3 | GENE REGULATION, DEADENYLATION, MRNA DECAY, CCR4-NOT, HYDROLASE, TRANSCRIPTION
4c0g:D (SER695) to (THR716) STRUCTURE OF THE NOT-BOX DOMAIN OF HUMAN CNOT3 | GENE REGULATION, DEADENYLATION, MRNA DECAY, CCR4-NOT, HYDROLASE, TRANSCRIPTION
4c0g:F (SER695) to (ASP717) STRUCTURE OF THE NOT-BOX DOMAIN OF HUMAN CNOT3 | GENE REGULATION, DEADENYLATION, MRNA DECAY, CCR4-NOT, HYDROLASE, TRANSCRIPTION
4r8y:A (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (R)-4-(2-CYCLOHEXYLETHYL)-4-(((R)-1-(2- CYCLOPENTYLACETYL)PYRROLIDIN-3-YL)METHYL)-1-METHYL-5-OXOIMIDAZOLIDIN- 2-IMINIUM | ASPARTYL PROTEASE, BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1, BETA-SITE APP CLEAVING ENZYME 1, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4r8y:B (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (R)-4-(2-CYCLOHEXYLETHYL)-4-(((R)-1-(2- CYCLOPENTYLACETYL)PYRROLIDIN-3-YL)METHYL)-1-METHYL-5-OXOIMIDAZOLIDIN- 2-IMINIUM | ASPARTYL PROTEASE, BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1, BETA-SITE APP CLEAVING ENZYME 1, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3cbn:A (SER84) to (ASP110) CRYSTAL STRUCTURE OF A CONSERVED PROTEIN (MTH639) FROM METHANOBACTERIUM THERMOAUTOTROPHICUM | RP-A, 10241D, PSI-II, NYSGXRC, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, UNKNOWN FUNCTION
4r91:A (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (R)-4-(2-CYCLOHEXYLETHYL)-4-(((1S,3R)-3- (CYCLOPENTYLAMINO)CYCLOHEXYL)METHYL)-1-METHYL-5-OXOIMIDAZOLIDIN-2- IMINIUM | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4r91:B (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (R)-4-(2-CYCLOHEXYLETHYL)-4-(((1S,3R)-3- (CYCLOPENTYLAMINO)CYCLOHEXYL)METHYL)-1-METHYL-5-OXOIMIDAZOLIDIN-2- IMINIUM | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4r92:A (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (R)-4-(2-CYCLOHEXYLETHYL)-4-(((1S,3R)-3- (ISONICOTINAMIDO)CYCLOHEXYL)METHYL)-1-METHYL-5-OXOIMIDAZOLIDIN-2- IMINIUM | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4r92:B (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (R)-4-(2-CYCLOHEXYLETHYL)-4-(((1S,3R)-3- (ISONICOTINAMIDO)CYCLOHEXYL)METHYL)-1-METHYL-5-OXOIMIDAZOLIDIN-2- IMINIUM | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4r93:A (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (R)-4-(2-CYCLOHEXYLETHYL)-1-METHYL-5-OXO-4- (((1S,3R)-3-(3-PHENYLUREIDO)CYCLOHEXYL)METHYL)IMIDAZOLIDIN-2-IMINIUM | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4r93:B (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (R)-4-(2-CYCLOHEXYLETHYL)-1-METHYL-5-OXO-4- (((1S,3R)-3-(3-PHENYLUREIDO)CYCLOHEXYL)METHYL)IMIDAZOLIDIN-2-IMINIUM | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4r95:A (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH 2-(((1R,3S)-3-(((R)-4-(2-CYCLOHEXYLETHYL)-2- IMINIO-1-METHYL-5-OXOIMIDAZOLIDIN-4-YL)METHYL)CYCLOHEXYL)AMINO) QUINOLIN-1-IUM | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4r95:B (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH 2-(((1R,3S)-3-(((R)-4-(2-CYCLOHEXYLETHYL)-2- IMINIO-1-METHYL-5-OXOIMIDAZOLIDIN-4-YL)METHYL)CYCLOHEXYL)AMINO) QUINOLIN-1-IUM | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4c1k:B (LYS10) to (ALA28) CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS 3-DEOXY-D-ARABINO- HEPTULOSONATE 7-PHOSPHATE SYNTHASE | TRANSFERASE, SHIKIMATE PATHWAY
4c1k:E (LYS10) to (ALA28) CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS 3-DEOXY-D-ARABINO- HEPTULOSONATE 7-PHOSPHATE SYNTHASE | TRANSFERASE, SHIKIMATE PATHWAY
4c1l:A (LYS10) to (ALA28) CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS 3-DEOXY-D-ARABINO- HEPTULOSONATE 7-PHOSPHATE SYNTHASE I181D INTERFACE MUTANT | TRANSFERASE, SHIKIMATE PATHWAY, INTERFACE MUTANT
4c1l:B (GLU9) to (ALA28) CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS 3-DEOXY-D-ARABINO- HEPTULOSONATE 7-PHOSPHATE SYNTHASE I181D INTERFACE MUTANT | TRANSFERASE, SHIKIMATE PATHWAY, INTERFACE MUTANT
4rap:L (ALA259) to (LYS280) CRYSTAL STRUCTURE OF BACTERIAL IRON-CONTAINING DODECAMERIC GLYCOSYLTRANSFERASE TIBC FROM ENTEROTOXIGENIC E.COLI H10407 | GT-B FOLD, TRANSFERASE, TIBA, ADP-HEPTOSE
4c1n:A (ALA62) to (ASP100) CORRINOID PROTEIN REACTIVATION COMPLEX WITH ACTIVATOR | OXIDOREDUCTASE-METAL BINDING PROTEIN COMPLEX
4c1n:D (VAL15) to (ASP55) CORRINOID PROTEIN REACTIVATION COMPLEX WITH ACTIVATOR | OXIDOREDUCTASE-METAL BINDING PROTEIN COMPLEX
4c1n:F (VAL15) to (ASP55) CORRINOID PROTEIN REACTIVATION COMPLEX WITH ACTIVATOR | OXIDOREDUCTASE-METAL BINDING PROTEIN COMPLEX
4rce:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH AMINOOXAZOLINE XANTHENE INHIBITOR 2 | ASPARTIC PROTEASE, ALZHEIMER'S DISEASE, APP, AMYLOID PRECURSOR PROTEIN, BRAIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4rcf:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH 2-AMINOOXAZOLINE 4- FLUOROXANTHENE INHIBITOR 49 | ASPARTIC PROTEASE, ALZHEIMER'S DISEASE, APP, AMYLOID PRECURSOR PROTEIN, BRAIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3cew:A (GLY59) to (ARG77) CRYSTAL STRUCTURE OF A CUPIN PROTEIN (BF4112) FROM BACTEROIDES FRAGILIS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET BFR205 | ALL BETA-PROTEIN, JELLY-ROLL (CUPIN-2), STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
3cew:B (GLY59) to (ARG77) CRYSTAL STRUCTURE OF A CUPIN PROTEIN (BF4112) FROM BACTEROIDES FRAGILIS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET BFR205 | ALL BETA-PROTEIN, JELLY-ROLL (CUPIN-2), STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
3cew:C (GLY59) to (ARG77) CRYSTAL STRUCTURE OF A CUPIN PROTEIN (BF4112) FROM BACTEROIDES FRAGILIS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET BFR205 | ALL BETA-PROTEIN, JELLY-ROLL (CUPIN-2), STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
3cew:D (GLY59) to (ARG77) CRYSTAL STRUCTURE OF A CUPIN PROTEIN (BF4112) FROM BACTEROIDES FRAGILIS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET BFR205 | ALL BETA-PROTEIN, JELLY-ROLL (CUPIN-2), STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
4re6:A (LYS294) to (PRO323) ACYLAMINOACYL PEPTIDASE COMPLEXED WITH A CHLOROMETHYLKETONE INHIBITOR | BETA-PROPELLER, ALPHA-BETA-HYDROLASE FOLD, CHLOROMETHYL-KETONE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3cib:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH727596 | BACE1, ASPARTYL PROTEASE, HYDROLASE
3cib:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH727596 | BACE1, ASPARTYL PROTEASE, HYDROLASE
3cid:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH726222 | BACE1, ASPARTYL PROTEASE, HYDROLASE
3cid:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH726222 | BACE1, ASPARTYL PROTEASE, HYDROLASE
3nhq:B (ALA28) to (PRO55) THE DARK PFR STRUCTURE OF THE PHOTOSENSORY CORE MODULE OF P. AERUGINOSA BACTERIOPHYTOCHROME | PHOTORECEPTOR, PHYTOCHROME, PAS, SIGNALING, SIGNALING PROTEIN
3nik:B (GLU131) to (CYS175) THE STRUCTURE OF UBR BOX (REAA) | E3 UBIQUITIN LIGASE, UBR BOX, ZINC-BINDING PROTEIN, N-END RULE, LIGASE, METAL BINDING PROTEIN
3nil:A (GLU131) to (CYS175) THE STRUCTURE OF UBR BOX (RDAA) | E3 UBIQUITIN LIGASE, UBR BOX, ZINC-BINDING PROTEIN, N-END RULE, LIGASE, METAL BINDING PROTEIN
3nil:B (GLU131) to (CYS175) THE STRUCTURE OF UBR BOX (RDAA) | E3 UBIQUITIN LIGASE, UBR BOX, ZINC-BINDING PROTEIN, N-END RULE, LIGASE, METAL BINDING PROTEIN
3nis:B (GLU131) to (CYS175) THE STRUCTURE OF UBR BOX (NATIVE2) | E3 UBIQUITIN LIGASE, UBR BOX, ZINC-BINDING PROTEIN, N-END RULE, LIGASE, METAL BINDING PROTEIN
3ckr:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH INHIBITOR | BETA-SECRETASE, ASPARTYL PROTEASE, ALTERNATIVE SPLICING, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
4c6n:A (ARG1784) to (VAL1801) CRYSTAL STRUCTURE OF THE DIHYDROOROTASE DOMAIN OF HUMAN CAD E1637T MUTANT BOUND TO SUBSTRATE AT PH 6.0 | HYDROLASE, DE NOVO PYRIMIDINE BIOSYNTHESIS, AMIDOHYDROLASE SUPERFAMILY, METALLOENZYME, ZINC BINDING, HISTIDINATE ANION
5fo3:A (CYS144) to (MSE161) ZAPC CELL DIVISION REGULATOR FROM E. COLI | CELL CYCLE, FTSZ, BACTERIAL CELL DIVISION, Z-RING ASSOCIATED PROTEIN C
5fo3:B (CYS144) to (MSE161) ZAPC CELL DIVISION REGULATOR FROM E. COLI | CELL CYCLE, FTSZ, BACTERIAL CELL DIVISION, Z-RING ASSOCIATED PROTEIN C
4c71:A (GLY365) to (PHE404) CRYSTAL STRUCTURE OF M. TUBERCULOSIS C171Q KASA IN COMPLEX WITH TLM18 | TRANSFERASE, BETO-KETOACYL-ACP SYNTHASE, KAS ENZYME, CONDENSING ENZYME, TYPE 2 FATTY ACID BIOSYNTHESIS, MYCOLIC ACID SYNTHESIS, THIOLACTOMYCIN
4c71:B (GLY365) to (PHE404) CRYSTAL STRUCTURE OF M. TUBERCULOSIS C171Q KASA IN COMPLEX WITH TLM18 | TRANSFERASE, BETO-KETOACYL-ACP SYNTHASE, KAS ENZYME, CONDENSING ENZYME, TYPE 2 FATTY ACID BIOSYNTHESIS, MYCOLIC ACID SYNTHESIS, THIOLACTOMYCIN
5fo9:B (LYS1546) to (SER1573) CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH CR1 (CCP15-17) | LIPID BINDING PROTEIN, COMPLEMENT SYSTEM, IMMUNE SYSTEM, PLASMA PROTEIN, REGULATORS OF COMPLEMENT ACTIVITY, COFACTOR ACTIVITY, DECAY ACCELERATING ACTIVITY
5fo9:E (LYS1551) to (SER1573) CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH CR1 (CCP15-17) | LIPID BINDING PROTEIN, COMPLEMENT SYSTEM, IMMUNE SYSTEM, PLASMA PROTEIN, REGULATORS OF COMPLEMENT ACTIVITY, COFACTOR ACTIVITY, DECAY ACCELERATING ACTIVITY
3nms:C (VAL1530) to (GLY1550) STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) IN COMPLEX WITH HUMAN COMPLEMENT C3C | COMPLEMENT ALTERNATE PATHWAY, COMPLEMENT PATHWAY, CONVERTASE, IMMUNE RESPONSE, INFLAMMATORY RESPONSE, INNATE IMMUNITY, SECRETED, VIRULENCE, IMMUNE EVASION, IMMUNE SYSTEM
4ca4:B (PHE1) to (ASN23) CRYSTAL STRUCTURE OF FIMH LECTIN DOMAIN WITH THE TYR48ALA MUTATION, IN COMPLEX WITH HEPTYL ALPHA-D-MANNOPYRANNOSIDE | CELL ADHESION, BACTERIAL ADHESIN, TYPE 1 FIMBRIAE, URINARY TRACT INFECTION, VARIABLE IMMUNOGLOBULIN FOLD, HEPTYL MANNOSE, FIMH ANTAGONIST
3nol:A (GLU46) to (ILE67) CRYSTAL STRUCTURE OF ZYMOMONAS MOBILIS GLUTAMINYL CYCLASE (TRIGONAL FORM) | BETA-PROPELLER, GLUTAMINYL CYCLASE, CYCLOTRANSFERASE, PYROGLUTAMATE, TRANSFERASE
3noy:A (ARG8) to (THR31) CRYSTAL STRUCTURE OF ISPG (GCPE) | IRON-SULFUR PROTEIN, NON-MEVALONATE PATHWAY, TERPENE BIOSYNTHESIS, ISOPRENOID BIOSYNTHESIS, TIM-BARREL N-DOMAIN, FERREDOXIN C-DOMAIN, CONVERTS 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE (ME-2,4CPP), 1- HYDROXY-2-METHYL-2-(E)-BUTENYL 4-DIPHOSPHATE, CYTOSOL, OXIDOREDUCTASE
3noy:B (ARG8) to (SER27) CRYSTAL STRUCTURE OF ISPG (GCPE) | IRON-SULFUR PROTEIN, NON-MEVALONATE PATHWAY, TERPENE BIOSYNTHESIS, ISOPRENOID BIOSYNTHESIS, TIM-BARREL N-DOMAIN, FERREDOXIN C-DOMAIN, CONVERTS 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE (ME-2,4CPP), 1- HYDROXY-2-METHYL-2-(E)-BUTENYL 4-DIPHOSPHATE, CYTOSOL, OXIDOREDUCTASE
3noy:C (ARG8) to (MET28) CRYSTAL STRUCTURE OF ISPG (GCPE) | IRON-SULFUR PROTEIN, NON-MEVALONATE PATHWAY, TERPENE BIOSYNTHESIS, ISOPRENOID BIOSYNTHESIS, TIM-BARREL N-DOMAIN, FERREDOXIN C-DOMAIN, CONVERTS 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE (ME-2,4CPP), 1- HYDROXY-2-METHYL-2-(E)-BUTENYL 4-DIPHOSPHATE, CYTOSOL, OXIDOREDUCTASE
5fs6:B (ASN241) to (ILE258) CRYSTAL STRUCTURE OF THE V243L MUTANT OF HUMAN APOPTOSIS INDUCING FACTOR | OXIDOREDUCTASE, MITOCHONDRIA, FLAVOPROTEIN
5fs7:B (ASN241) to (ILE258) CRYSTAL STRUCTURE OF THE G262S MUTANT OF HUMAN APOPTOSIS INDUCING FACTOR | MITOCHONDRIA, FLAVOPROTEIN, OXIDOREDUCTASE
5fs9:A (ASN241) to (PRO264) CRYSTAL STRUCTURE OF THE G338E MUTANT OF HUMAN APOPTOSIS INDUCING FACTOR | MITOCHONDRIA, FLAVOPROTEIN, OXIDOREDUCTASE
5fs9:B (ASN241) to (PRO264) CRYSTAL STRUCTURE OF THE G338E MUTANT OF HUMAN APOPTOSIS INDUCING FACTOR | MITOCHONDRIA, FLAVOPROTEIN, OXIDOREDUCTASE
3npf:B (VAL40) to (LEU66) CRYSTAL STRUCTURE OF A PUTATIVE DIPEPTIDYL-PEPTIDASE VI (BACOVA_00612) FROM BACTEROIDES OVATUS AT 1.72 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, HYDROLASE
3nsu:B (LEU497) to (VAL522) A SYSTEMATIC SCREEN FOR PROTEIN-LIPID INTERACTIONS IN SACCHAROMYCES CEREVISIAE | PLECKSTRIN HOMOLOGY DOMAIN, SIGNALING PROTEIN
4rqu:A (LYS138) to (ASN164) ALCOHOL DEHYDROGENASE CRYSTAL STRUCTURE IN COMPLEX WITH NAD | ROSSMANN FOLD, ALCOHOL DEHYDROGENASE, NAD, OXIDOREDUCTASE
3cs0:A (ALA374) to (GLY404) CRYSTAL STRUCTURE OF DEGP24 | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE
3nw8:C (SER560) to (VAL583) GLYCOPROTEIN B FROM HERPES SIMPLEX VIRUS TYPE 1, Y179S MUTANT, HIGH-PH | ENVELOPE GLYCOPROTEIN, MEMBRANE FUSION, VIRAL PROTEIN, GLYCOPROTEIN B, HERPESVIRUS 1, HSV-1, MEMBRANE
3nwd:C (VAL581) to (THR626) GLYCOPROTEIN B FROM HERPES SIMPLEX VIRUS TYPE 1, Y179S MUTANT, LOW-PH | COILED-COIL, ENVELOPE GLYCOPROTEIN, MEMBRANE FUSION, VIRAL PROTEIN, GLYCOPROTEIN B, HERPESVIRUS 1, HSV-1, MEMBRANE
3csn:A (GLY764) to (LYS809) STRUCTURE OF THE SERRATIA MARCESCENS HEMOPHORE RECEPTOR HASR IN COMPLEX WITH ITS HEMOPHORE HASA | OUTER MEMBRANE PROTEIN, BETA-BARREL, HEMOPHORE RECEPTOR, TONB BOX, HEME, IRON, METAL-BINDING, SECRETED, MEMBRANE PROTEIN-HEME BINDING PROTEIN COMPLEX
3csn:B (GLY764) to (LYS809) STRUCTURE OF THE SERRATIA MARCESCENS HEMOPHORE RECEPTOR HASR IN COMPLEX WITH ITS HEMOPHORE HASA | OUTER MEMBRANE PROTEIN, BETA-BARREL, HEMOPHORE RECEPTOR, TONB BOX, HEME, IRON, METAL-BINDING, SECRETED, MEMBRANE PROTEIN-HEME BINDING PROTEIN COMPLEX
4chv:A (GLY278) to (GLY297) THE ELECTRON CRYSTALLOGRAPHY STRUCTURE OF THE CAMP-BOUND POTASSIUM CHANNEL MLOK1 | TRANSPORT, 2DX, VOLTAGE GATED POTASSIUM CHANNEL, CNBD, 2D CRYSTAL
4chv:B (GLY278) to (GLY297) THE ELECTRON CRYSTALLOGRAPHY STRUCTURE OF THE CAMP-BOUND POTASSIUM CHANNEL MLOK1 | TRANSPORT, 2DX, VOLTAGE GATED POTASSIUM CHANNEL, CNBD, 2D CRYSTAL
4chv:D (GLY278) to (GLY297) THE ELECTRON CRYSTALLOGRAPHY STRUCTURE OF THE CAMP-BOUND POTASSIUM CHANNEL MLOK1 | TRANSPORT, 2DX, VOLTAGE GATED POTASSIUM CHANNEL, CNBD, 2D CRYSTAL
4rso:A (PRO482) to (GLY544) THE STRUCTURE OF THE NEUROTROPIC AAVRH.8 VIRAL VECTOR | BETA-BARREL, VIRUS, CAPSID PROTEIN, ICOSAHEDRAL VIRUS, ADENO- ASSOCIATED VIRUS, PARVOVIRIDAE, DEPENDOPARVOVIRUS, VIRUS CAPSID PROTEIN, SINGLE-STRANDED DNA BINDING
4clm:A (LYS2) to (ARG25) STRUCTURE OF SALMONELLA TYPHI TYPE I DEHYDROQUINASE IRREVERSIBLE INHIBITED WITH A 1,3,4-TRIHYDROXYCICLOHEXANE- 1-CARBOXYLIC ACID DERIVATIVE | TYPE I DEHYDROQUINASE, LYASE, INHIBITOR, SHIKIMIS ACID PATHWAY, SUBSTRATE SPECIFICITY
4clm:B (LYS2) to (ARG25) STRUCTURE OF SALMONELLA TYPHI TYPE I DEHYDROQUINASE IRREVERSIBLE INHIBITED WITH A 1,3,4-TRIHYDROXYCICLOHEXANE- 1-CARBOXYLIC ACID DERIVATIVE | TYPE I DEHYDROQUINASE, LYASE, INHIBITOR, SHIKIMIS ACID PATHWAY, SUBSTRATE SPECIFICITY
3cy1:A (ASP291) to (LEU308) CRYSTAL STRUCTURE OF THE CYTOCHROME P450 CYP121 S279A MUTANT FROM M. TUBERCULOSIS | CYTOCHROME P450, CYP121, MYCOBACTERIUM TUBERCULOSIS, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE
3o4j:C (LYS294) to (PRO323) STRUCTURE AND CATALYSIS OF ACYLAMINOACYL PEPTIDASE | ALPHA/BETA HYDROLASE FOLD, BETA PROPELLER, HYDROLASE, OLIGOPEPTIDASE, SIZE SELECTIVITY
4cnn:A (LYS2) to (ARG25) HIGH RESOLUTION STRUCTURE OF SALMONELLA TYPHI TYPE I DEHYDROQUINASE | BACTERIAL PROTEINS, BINDING SITES, SHIKIMIS ACID PATHWAY, LYASE
4cnn:B (LYS2) to (ARG25) HIGH RESOLUTION STRUCTURE OF SALMONELLA TYPHI TYPE I DEHYDROQUINASE | BACTERIAL PROTEINS, BINDING SITES, SHIKIMIS ACID PATHWAY, LYASE
4cno:A (LYS2) to (ARG25) STRUCTURE OF THE SALMONELLA TYPHI TYPE I DEHYDROQUINASE INHIBITED BY A 3-DEHYDROQUINIC ACID DERIVATIVE | LYASE, INHIBITOR, PROTEIN BINDING, SHIKIMIS ACID PATHWAY, SUBSTRATE SPECIFICITY
4cno:B (THR3) to (ARG25) STRUCTURE OF THE SALMONELLA TYPHI TYPE I DEHYDROQUINASE INHIBITED BY A 3-DEHYDROQUINIC ACID DERIVATIVE | LYASE, INHIBITOR, PROTEIN BINDING, SHIKIMIS ACID PATHWAY, SUBSTRATE SPECIFICITY
4cnp:A (MET1) to (ARG25) STRUCTURE OF THE SALMONELLA TYPHI TYPE I DEHYDROQUINASE INHIBITED BY A 3-EPIQUINIC ACID DERIVATIVE | SHIKIMIS ACID PATHWAY, LYASE
3o52:B (GLY45) to (ILE81) STRUCTURE OF THE E.COLI GDP-MANNOSE HYDROLASE (YFFH) IN COMPLEX WITH TARTRATE | NUDIX, GDP_MANNOSE, HYDROLASE, BIOFILM, TARTRATE, NUDIX FOLD, GDP- MANNOSE HYDROLASE
3o52:C (GLY45) to (ILE81) STRUCTURE OF THE E.COLI GDP-MANNOSE HYDROLASE (YFFH) IN COMPLEX WITH TARTRATE | NUDIX, GDP_MANNOSE, HYDROLASE, BIOFILM, TARTRATE, NUDIX FOLD, GDP- MANNOSE HYDROLASE
3o52:E (GLY45) to (ILE81) STRUCTURE OF THE E.COLI GDP-MANNOSE HYDROLASE (YFFH) IN COMPLEX WITH TARTRATE | NUDIX, GDP_MANNOSE, HYDROLASE, BIOFILM, TARTRATE, NUDIX FOLD, GDP- MANNOSE HYDROLASE
4s23:A (PRO9) to (THR32) STRUCTURE OF THE GCPE-HMBPP COMPLEX FROM THERMUS THERMOPHILIUS | TIM BARREL, ALPHA/BETA FOLD, OXIDOREDUCTASE
3d4r:A (ASP63) to (GLY90) CRYSTAL STRUCTURE OF A DUF2118 FAMILY PROTEIN (MMP0046) FROM METHANOCOCCUS MARIPALUDIS AT 2.20 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
3d4r:C (ASP63) to (GLY90) CRYSTAL STRUCTURE OF A DUF2118 FAMILY PROTEIN (MMP0046) FROM METHANOCOCCUS MARIPALUDIS AT 2.20 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
3d4r:E (ASP63) to (GLY90) CRYSTAL STRUCTURE OF A DUF2118 FAMILY PROTEIN (MMP0046) FROM METHANOCOCCUS MARIPALUDIS AT 2.20 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
3od0:A (GLY161) to (GLY182) CRYSTAL STRUCTURE OF CGMP BOUND CGMP-DEPENDENT PROTEIN KINASE(92-227) | SERINE/THREONINE KINASE, TF2I AND IRAG, TRANSFERASE
3oex:B (ALA0) to (THR26) CRYSTAL STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE (AROD) FROM SALMONELLA TYPHIMURIUM WITH CLOSE LOOP CONFORMATION. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, TIM BARREL, LYASE
3ofl:C (ALA164) to (GLY204) CRYSTAL STRUCTURE OF HUMANPAPILLOMAVIRUS18 (HPV18) CAPSID L1 PENTAMERS BOUND TO HEPARIN OLIGOSACCHARIDES | PROTEIN OLIGOSACCHARIDE COMPLEX, JELLY ROLL, CAPSID PROTEIN, BINDS TO HOST RECEPTOR, RECEPTOR HEPARIN OLIGO SACCHARIDES, VIRUS CAPSID, STRUCTURAL PROTEIN
3ofl:M (ALA164) to (GLY204) CRYSTAL STRUCTURE OF HUMANPAPILLOMAVIRUS18 (HPV18) CAPSID L1 PENTAMERS BOUND TO HEPARIN OLIGOSACCHARIDES | PROTEIN OLIGOSACCHARIDE COMPLEX, JELLY ROLL, CAPSID PROTEIN, BINDS TO HOST RECEPTOR, RECEPTOR HEPARIN OLIGO SACCHARIDES, VIRUS CAPSID, STRUCTURAL PROTEIN
3ofu:A (ALA289) to (PRO307) CRYSTAL STRUCTURE OF CYTOCHROME P450 CYP101C1 | OXIDOREDUCTASE
4trw:A (TYR403) to (PRO434) STRUCTURE OF BACE1 COMPLEX WITH A SYN-HEA-TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDRASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4trw:C (TYR403) to (PRO434) STRUCTURE OF BACE1 COMPLEX WITH A SYN-HEA-TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDRASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4trz:A (TYR403) to (PRO434) STRUCTURE OF BACE1 COMPLEX WITH 2-THIOPHENYL HEA-TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDRASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4tsm:A (THR1128) to (ASN1147) MBP-FUSION PROTEIN OF PILA1 FROM C. DIFFICILE R20291 RESIDUES 26-166 | PILIN, T4P, FUSION, CELL ADHESION
4tsm:C (THR1128) to (ASN1147) MBP-FUSION PROTEIN OF PILA1 FROM C. DIFFICILE R20291 RESIDUES 26-166 | PILIN, T4P, FUSION, CELL ADHESION
3ohh:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH BMS-681889 AKA N~1~-BUTYL-5-CYANO- N~3~-((1S,2R)-1-(3,5- DIFLUOROBENZYL)-2-HYDROXY-3-((3- METHOXYBENZYL)AMINO)PROPYL)-N~1~- METHYL-1H-INDOLE-1,3- DICARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2,ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ohh:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH BMS-681889 AKA N~1~-BUTYL-5-CYANO- N~3~-((1S,2R)-1-(3,5- DIFLUOROBENZYL)-2-HYDROXY-3-((3- METHOXYBENZYL)AMINO)PROPYL)-N~1~- METHYL-1H-INDOLE-1,3- DICARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2,ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5gke:A (LYS38) to (LYS59) STRUCTURE OF ENDOMS-DSDNA1 COMPLEX | ENDONUCLEASES, DNA-BINDING, HYDROLASE-DNA COMPLEX
5gke:B (LYS38) to (LYS59) STRUCTURE OF ENDOMS-DSDNA1 COMPLEX | ENDONUCLEASES, DNA-BINDING, HYDROLASE-DNA COMPLEX
5gki:B (LYS38) to (LYS59) STRUCTURE OF ENDOMS-DSDNA3 COMPLEX | ENDONUCLEASE, DNA COMPLEX, HYDROLASE-DNA COMPLEX
4tw1:H (GLY242) to (PRO283) CRYSTAL STRUCTURE OF THE OCTAMERIC PORE COMPLEX OF THE STAPHYLOCOCCUS AUREUS BI-COMPONENT TOXIN LUKGH | OCTAMER LEUKOCIDIN PORE-FORMING TOXIN, TOXIN
4tw1:N (GLY242) to (PRO283) CRYSTAL STRUCTURE OF THE OCTAMERIC PORE COMPLEX OF THE STAPHYLOCOCCUS AUREUS BI-COMPONENT TOXIN LUKGH | OCTAMER LEUKOCIDIN PORE-FORMING TOXIN, TOXIN
4tw1:P (GLY242) to (PRO283) CRYSTAL STRUCTURE OF THE OCTAMERIC PORE COMPLEX OF THE STAPHYLOCOCCUS AUREUS BI-COMPONENT TOXIN LUKGH | OCTAMER LEUKOCIDIN PORE-FORMING TOXIN, TOXIN
4d5d:B (ASN55) to (ASP88) CRYSTAL STRUCTURE OF CYMA FROM KLEBSIELLA OXYTOCA | STRUCTURAL PROTEIN, OUTER MEMBRANE CHANNEL CYCLODEXTRIN TRANSPORT BETA BARREL MONOMER
3ooq:F (ASP360) to (GLU389) CRYSTAL STRUCTURE OF AMIDOHYDROLASE FROM THERMOTOGA MARITIMA MSB8 | STRUCTURAL GENOMICS, CRYSTAL STRUCTURE,PROTEIN STRUCTURE INITIATIVE, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, HYDROLASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
4tz4:A (LEU76) to (ILE100) CRYSTAL STRUCTURE OF HUMAN CEREBLON IN COMPLEX WITH DDB1 AND LENALIDOMIDE | DCAF, DNA BINDING PROTEIN-LIGASE COMPLEX
3ooz:A (TYR404) to (PRO435) BACE1 IN COMPLEX WITH THE AMINOHYDANTOIN COMPOUND 102 | INHIBITOR, BETA-SECRETASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4d8c:C (TYR335) to (PRO366) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE IN COMPLEX WITH NVP-BXD552, DERIVED FROM A CO-CRYSTALLIZATION EXPERIMENT | BETA-SECRETASE, MEMAPSIN2, BACE1, ASPARTIC PROTEINASE, ALZHEIMER'S DISEASE, ENZYME INHIBITOR COMPLEX, STRUCTURE-BASED DRUG DESIGN, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4d9p:A (ASP4) to (THR29) CRYSTAL STRUCTURE OF B. ANTHRACIS DHPS WITH COMPOUND 17 | TIM BARREL, TRANSFERASE, DHPS INHIBITORS, PABA, PTERIN, DHPP, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4dai:B (ASP4) to (LEU26) CRYSTAL STRUCTURE OF B. ANTHRACIS DHPS WITH COMPOUND 23 | PABA, DHPP, PTERIN, DHPS INHIBITORS, TIM BARREL, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4u2q:A (GLN333) to (LEU361) FULL-LENGTH AMPA SUBTYPE IONOTROPIC GLUTAMATE RECEPTOR GLUA2 IN COMPLEX WITH PARTIAL AGONIST KAINATE | AMPA RECEPTOR, TRANSPORT PROTEIN, MEMBRANE PROTEIN
4u2q:B (GLN333) to (LYS362) FULL-LENGTH AMPA SUBTYPE IONOTROPIC GLUTAMATE RECEPTOR GLUA2 IN COMPLEX WITH PARTIAL AGONIST KAINATE | AMPA RECEPTOR, TRANSPORT PROTEIN, MEMBRANE PROTEIN
4u2q:D (GLN333) to (LYS362) FULL-LENGTH AMPA SUBTYPE IONOTROPIC GLUTAMATE RECEPTOR GLUA2 IN COMPLEX WITH PARTIAL AGONIST KAINATE | AMPA RECEPTOR, TRANSPORT PROTEIN, MEMBRANE PROTEIN
4db7:A (ASP4) to (ILE25) CRYSTAL STRUCTURE OF B. ANTHRACIS DHPS WITH COMPOUND 25 | TIM BARREL, TRANSFERASE, PABA, DHPP, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4dbl:C (VAL4) to (PRO34) CRYSTAL STRUCTURE OF E159Q MUTANT OF BTUCDF | ABC TRANSPORTER FOR VITAMIN B12, ATP BINDING, INNER MEMBRANE, TRANSPORT PROTEIN
4dbl:D (VAL4) to (PRO34) CRYSTAL STRUCTURE OF E159Q MUTANT OF BTUCDF | ABC TRANSPORTER FOR VITAMIN B12, ATP BINDING, INNER MEMBRANE, TRANSPORT PROTEIN
4dbl:H (VAL4) to (PRO34) CRYSTAL STRUCTURE OF E159Q MUTANT OF BTUCDF | ABC TRANSPORTER FOR VITAMIN B12, ATP BINDING, INNER MEMBRANE, TRANSPORT PROTEIN
4dbl:I (VAL4) to (PRO34) CRYSTAL STRUCTURE OF E159Q MUTANT OF BTUCDF | ABC TRANSPORTER FOR VITAMIN B12, ATP BINDING, INNER MEMBRANE, TRANSPORT PROTEIN
3duy:C (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA-SECRETASE IN COMPLEX WITH NVP-AFJ144 | BETA-SECRETASE, BACE1, MEMAPSIN2, ENZYME INHIBITOR COMPLEX, ALZHEIMER'S DISEASE, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3dv5:C (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA-SECRETASE IN COMPLEX WITH NVP-BAV544 | BETA-SECRETASE, MEMAPSIN2, BACE1, ASPARTIC PROTEASE, ALZHEIMER'S DISEASE, ENZYME INHIBITOR COMPLEX, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
5hce:A (SER1567) to (GLY1588) TERNARY COMPLEX OF HUMAN COMPLEMENT C5 WITH ORNITHODOROS MOUBATA OMCI AND RHIPICEPHALUS APPENDICULATUS RACI1 | COMPLEMENT, INFLAMMATION, INHIBITOR, TICK, IMMUNE SYSTEM
5hd0:A (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (7AR)-7A-(4-(3-CYANOPHENYL)THIOPHEN-2-YL)-6-(5- FLUOROPYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H-PYRROLO[3,4- D]PYRIMIDIN-2-IMINIUM | ASPARTYL PROTEASE, BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1, BETA-SITE APP CLEAVING ENZYME 1, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hd0:B (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (7AR)-7A-(4-(3-CYANOPHENYL)THIOPHEN-2-YL)-6-(5- FLUOROPYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H-PYRROLO[3,4- D]PYRIMIDIN-2-IMINIUM | ASPARTYL PROTEASE, BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1, BETA-SITE APP CLEAVING ENZYME 1, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hdv:A (TYR403) to (PRO434) BACE-1 INCOMPLEX WITH (7AR)-7A-(5-CYANOTHIOPHEN-2-YL)-6-(5-FLUORO-4- METHOXY-6-METHYLPYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H-PYRROLO[3, 4-D]PYRIMIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hdv:B (TYR403) to (PRO434) BACE-1 INCOMPLEX WITH (7AR)-7A-(5-CYANOTHIOPHEN-2-YL)-6-(5-FLUORO-4- METHOXY-6-METHYLPYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H-PYRROLO[3, 4-D]PYRIMIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hdu:A (TYR403) to (PRO434) BACE-1 INCOMPLEX WITH (7AR)-7A-(4-(3-CYANOPHENYL)THIOPHEN-2-YL)-6-(5- FLUORO-4-METHOXYPYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H-PYRROLO[3, 4-D]PYRIMIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hdu:B (TYR403) to (PRO434) BACE-1 INCOMPLEX WITH (7AR)-7A-(4-(3-CYANOPHENYL)THIOPHEN-2-YL)-6-(5- FLUORO-4-METHOXYPYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H-PYRROLO[3, 4-D]PYRIMIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4u4c:A (VAL696) to (CYS757) THE MOLECULAR ARCHITECTURE OF THE TRAMP COMPLEX REVEALS THE ORGANIZATION AND INTERPLAY OF ITS TWO CATALYTIC ACTIVITIES | HELICASE, ATPASE, POLY(A)POLYMERASE, RNA DEGRADATION, EXOSOME, HYDROLASE
5hdx:A (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (7AR)-7A-(5-CYANOTHIOPHEN-2-YL)-6-(4-ETHOXY-5- FLUORO-6-METHYLPYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H-PYRROLO[3, 4-D]PYRIMIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hdx:B (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (7AR)-7A-(5-CYANOTHIOPHEN-2-YL)-6-(4-ETHOXY-5- FLUORO-6-METHYLPYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H-PYRROLO[3, 4-D]PYRIMIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hdz:A (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (7AR)-7A-(5-CYANOTHIOPHEN-2-YL)-6-(5-FLUORO-4- METHYL-6-(METHYLTHIO)PYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H- PYRROLO[3,4-D]PYRIMIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hdz:B (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (7AR)-7A-(5-CYANOTHIOPHEN-2-YL)-6-(5-FLUORO-4- METHYL-6-(METHYLTHIO)PYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H- PYRROLO[3,4-D]PYRIMIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5he4:A (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (4AR,7AS)-7A-(2,6-DIFLUOROPHENYL)-6-(5-FLUORO- 4-METHOXY-6-METHYLPYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H- PYRROLO[3,4-D]PYRIMIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5he4:B (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (4AR,7AS)-7A-(2,6-DIFLUOROPHENYL)-6-(5-FLUORO- 4-METHOXY-6-METHYLPYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H- PYRROLO[3,4-D]PYRIMIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5he5:A (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (7AR)-7A-(5-CYANOTHIOPHEN-2-YL)-6-(5-FLUORO-4- METHYL-6-(METHYLAMINO)PYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H- PYRROLO[3,4-D]PYRIMIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5he5:B (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (7AR)-7A-(5-CYANOTHIOPHEN-2-YL)-6-(5-FLUORO-4- METHYL-6-(METHYLAMINO)PYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H- PYRROLO[3,4-D]PYRIMIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5he7:A (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (4AR,7AS)-7A-(2,4-DIFLUOROPHENYL)-6-(5-FLUORO- 4-METHOXY-6-METHYLPYRIMIDIN-2-YL)-2-IMINO-3-METHYLOCTAHYDRO-4H- PYRROLO[3,4-D]PYRIMIDIN-4-ONE | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5he7:B (TYR403) to (PRO434) BACE-1 IN COMPLEX WITH (4AR,7AS)-7A-(2,4-DIFLUOROPHENYL)-6-(5-FLUORO- 4-METHOXY-6-METHYLPYRIMIDIN-2-YL)-2-IMINO-3-METHYLOCTAHYDRO-4H- PYRROLO[3,4-D]PYRIMIDIN-4-ONE | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3dxj:D (ARG1151) to (MET1168) CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH THE ANTIBIOTIC MYXOPYRONIN | RNA POLYMERASE; RNAP; DRUG COMPLEX; INHIBITOR; CORALLOPYRONIN; RIPOSTATIN; TRANSCRIPTION; HOLOENZYME; CRYSTALLOGRAPHY; TWINNING; HEMIHEDRAL, DNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, TRANSFERASE, DNA-BINDING, SIGMA FACTOR, TRANSCRIPTION REGULATION, TRANSCRIPTION,TRANSFERASE
4u5b:B (GLN331) to (ASN355) CRYSTAL STRUCTURE OF GLUA2 A622T, CON-IKOT-IKOT SNAIL TOXIN, PARTIAL AGONIST KA AND POSTITIVE MODULATOR (R,R)-2B COMPLEX | AMPA RECEPTOR, TRANSPORT PROTEIN-TOXIN COMPLEX
4u5f:B (GLN331) to (ASN355) CRYSTAL STRUCTURE OF GLUA2, CON-IKOT-IKOT SNAIL TOXIN, PARTIAL AGONIST KA AND POSTITIVE MODULATOR (R,R)-2B COMPLEX, GLUA2CRYST2 CONSTRUCT | AMPA RECEPTOR, TRANSPORT PROTEIN-TOXIN COMPLEX
3p0q:A (SER1124) to (ARG1159) HUMAN TANKYRASE 2 - CATALYTIC PARP DOMAIN IN COMPLEX WITH AN INHIBITOR | PROTEIN-LIGAND COMPLEX, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, DIPHTHERIA TOXIN LIKE FOLD, TRANSFERASE, NAD+, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4djd:E (ALA62) to (SER99) CRYSTAL STRUCTURE OF FOLATE-FREE CORRINOID IRON-SULFUR PROTEIN (CFESP) IN COMPLEX WITH ITS METHYLTRANSFERASE (METR) | TIM BARREL, ROSSMANN FOLD, B12-DEPENDENT METHYLTRANSFERASE, TRANSFERASE-VITAMIN-BINDING PROTEIN COMPLEX
4dje:F (GLN15) to (ASP62) CRYSTAL STRUCTURE OF FOLATE-BOUND CORRINOID IRON-SULFUR PROTEIN (CFESP) IN COMPLEX WITH ITS METHYLTRANSFERASE (METR), CO-CRYSTALLIZED WITH FOLATE | TIM BARREL, ROSSMANN FOLD, B12-DEPENDENT METHYLTRANSFERASE, TRANSFERASE-VITAMIN-BINDING PROTEIN COMPLEX
4djf:D (GLN15) to (ASN52) CRYSTAL STRUCTURE OF FOLATE-BOUND CORRINOID IRON-SULFUR PROTEIN (CFESP) IN COMPLEX WITH ITS METHYLTRANSFERASE (METR), CO-CRYSTALLIZED WITH FOLATE AND TI(III) CITRATE REDUCTANT | TIM BARREL, ROSSMANN FOLD, B12-DEPENDENT METHYLTRANSFERASE, TRANSFERASE-VITAMIN-BINDING PROTEIN COMPLEX
4dju:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 2-IMINO-3-METHYL-5,5-DIPHENYLIMIDAZOLIDIN- 4-ONE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4dju:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 2-IMINO-3-METHYL-5,5-DIPHENYLIMIDAZOLIDIN- 4-ONE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4djv:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 2-IMINO-5-(3'-METHOXY-[1,1'-BIPHENYL]-3- YL)-3-METHYL-5-PHENYLIMIDAZOLIDIN-4-ONE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4djv:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 2-IMINO-5-(3'-METHOXY-[1,1'-BIPHENYL]-3- YL)-3-METHYL-5-PHENYLIMIDAZOLIDIN-4-ONE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4djw:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 2-IMINO-3-METHYL-5-PHENYL-5-(3-(PYRIDIN-3- YL)PHENYL)IMIDAZOLIDIN-4-ONE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4djw:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 2-IMINO-3-METHYL-5-PHENYL-5-(3-(PYRIDIN-3- YL)PHENYL)IMIDAZOLIDIN-4-ONE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4djy:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO (R)-5-CYCLOPROPYL-2-IMINO-3-METHYL-5-(3-(5- (PROP-1-YN-1-YL)PYRIDIN-3-YL)PHENYL)IMIDAZOLIDIN-4-ONE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3p3x:A (ASP301) to (MET317) CRYSTAL STRUCTURE OF THE CYTOCHROME P450 MONOOXYGENASE AURH (NTERM- AURH-I) FROM STREPTOMYCES THIOLUTEUS | CYTOCHROME P450 MONOOXYGENASE, OXIDATION OF DEOXYAUREOTHIN TO AUREOTHIN, OXIDOREDUCTASE
3e0m:B (HIS269) to (ALA294) CRYSTAL STRUCTURE OF FUSION PROTEIN OF MSRA AND MSRB | FUSION, MSRAB, LINKER, HINGE, CELL MEMBRANE, MEMBRANE, MULTIFUNCTIONAL ENZYME, OXIDOREDUCTASE
3e0o:D (HIS101) to (PRO125) CRYSTAL STRUCTURE OF MSRB | MSRB, OXIDOREDUCTASE
3e0o:E (HIS101) to (PRO125) CRYSTAL STRUCTURE OF MSRB | MSRB, OXIDOREDUCTASE
4dnu:A (GLY353) to (ILE374) CRYSTAL STRUCTURE OF THE W285A MUTANT OF UVB-RESISTANCE PROTEIN UVR8 | WD40 REPEATS, UV-B PERCEPTION, COP1, GENE REGULATION
4dnv:B (GLY353) to (ILE374) CRYSTAL STRUCTURE OF THE W285F MUTANT OF UVB-RESISTANCE PROTEIN UVR8 | WD40 REPEATS, UV-B PERCEPTION, COP1, GENE REGULATION
4dnv:C (GLY301) to (VAL322) CRYSTAL STRUCTURE OF THE W285F MUTANT OF UVB-RESISTANCE PROTEIN UVR8 | WD40 REPEATS, UV-B PERCEPTION, COP1, GENE REGULATION
4dnw:B (GLY353) to (ILE374) CRYSTAL STRUCTURE OF UVB-RESISTANCE PROTEIN UVR8 | WD40 REPEATS, UV-B PERCEPTION, COP1, GENE REGULATION
5hrm:B (LEU333) to (ASN357) CRYSTAL STRUCTURE OF PHOSPHOTRIESTERASE FROM SPHINGOBIUM SP. TCM1 | PHOSPHOTRIESTERASE, HYDROLASE, BETA-PROPELLER, ORGANOPHOSPHATE DEGRADATION
4dpi:A (TYR390) to (PRO421) BACE-1 IN COMPLEX WITH HEA-MACROCYCLIC INHIBITOR, MV078512 | BACE1, ASP2, BACE, MACROCYCLE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hu0:A (TYR403) to (PRO434) BACE1 IN COMPLEX WITH 4-(3-(FURAN-2-CARBOXAMIDO)PHENYL)-1-METHYL-5- OXO-4-PHENYLIMIDAZOLIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hu0:B (TYR403) to (PRO434) BACE1 IN COMPLEX WITH 4-(3-(FURAN-2-CARBOXAMIDO)PHENYL)-1-METHYL-5- OXO-4-PHENYLIMIDAZOLIDIN-2-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hu1:A (TYR403) to (PRO434) BACE1 IN COMPLEX WITH (R)-N-(3-(3-AMINO-2,5-DIMETHYL-1,1-DIOXIDO-5,6- DIHYDRO-2H-1,2,4-THIADIAZIN-5-YL)-4-FLUOROPHENYL)-5- FLUOROPICOLINAMIDE | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hu1:B (TYR403) to (PRO434) BACE1 IN COMPLEX WITH (R)-N-(3-(3-AMINO-2,5-DIMETHYL-1,1-DIOXIDO-5,6- DIHYDRO-2H-1,2,4-THIADIAZIN-5-YL)-4-FLUOROPHENYL)-5- FLUOROPICOLINAMIDE | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3e4e:A (ASP375) to (THR392) HUMAN CYTOCHROME P450 2E1 IN COMPLEX WITH THE INHIBITOR 4- METHYLPYRAZOLE | CYP2E1, P450 2E1, MONOOXYGENASE, ACETAMINOPHEN, OXIDOREDUCTASE, HEME, ENDOPLASMIC RETICULUM, IRON, MEMBRANE, METAL-BINDING, MICROSOME
3e4e:B (ASP375) to (THR392) HUMAN CYTOCHROME P450 2E1 IN COMPLEX WITH THE INHIBITOR 4- METHYLPYRAZOLE | CYP2E1, P450 2E1, MONOOXYGENASE, ACETAMINOPHEN, OXIDOREDUCTASE, HEME, ENDOPLASMIC RETICULUM, IRON, MEMBRANE, METAL-BINDING, MICROSOME
5hyt:H (SER0) to (THR32) STRUCTURE OF HUMAN C4B-BINIDNG PROTEIN ALPHA CHAIN CCP DOMAINS 1 AND 2 IN COMPLEX WITH THE HYPERVARIABLE REGION OF GROUP A STREPTOCOCCUS M22 PROTEIN | M PROTEIN, COMPLEMENT, STREPTOCOCCUS PYOGENES, HYPERVARIABLE ANTIGEN, IMMUNE SYSTEM
5hyu:B (SER0) to (THR32) STRUCTURE OF HUMAN C4B-BINDING PROTEIN ALPHA CHAIN CCP DOMAINS 1 AND 2 IN COMPLEX WITH THE HYPERVARIABLE REGION OF GROUP A STREPTOCOCCUS M2 PROTEIN | M PROTEIN, COMPLEMENT, STREPTOCOCCUS PYOGENES, HYPERVARIABLE ANTIGEN, IMMUNE SYSTEM
4ufj:A (MET543) to (GLY569) MOUSE GALACTOCEREBROSIDASE COMPLEXED WITH ISO-GALACTO- FAGOMINE LACTAM IGL | HYDROLASE, GLYCOSYL HYDROLASE, COMPLEX, LYSOSOME
5i0q:B (SER0) to (THR32) STRUCTURE OF HUMAN C4B-BINDING PROTEIN ALPHA CHAIN CCP DOMAINS 1 AND 2 IN COMPLEX WITH THE HYPERVARIABLE REGION OF MUTANT GROUP A STREPTOCOCCUS M2 (K65A, N66A) PROTEIN | M PROTEIN, COMPLEMENT, STREPTOCOCCUS PYOGENES, HYPERVARIABLE ANTIGEN, IMMUNE SYSTEM
4uhg:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH TA-21 | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4dv9:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 WITH ITS INHIBITOR | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4dvf:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 WITH ITS INHIBITOR | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4dvi:B (SER1277) to (LYS1312) CRYSTAL STRUCTURE OF TANKYRASE 1 WITH IWR2 | TANKYRASE, PARP, INHIBITOR, IWR2, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3pi5:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE IN COMPLEX WITH BFG356 | ENZYME INHIBITOR COMPLEX, ASPARTIC PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4uio:A (THR3) to (ARG25) STRUCTURE OF THE SALMONELLA TYPHI TYPE I DEHYDROQUINASE COVALENTLY INHIBITED BY A 3-DEHYDROQUINIC ACID DERIVATIVE | BACTERIAL PROTEINS, BINDING SITES, CRYSTALLIZATION, LYASE, INHIBITOR, PROTEIN BINDING, SHIKIMIS ACID PATHWAY, SUBSTRATE SPECIFICITY
4umz:A (GLU300) to (LEU319) PIKC D50N MUTANT IN COMPLEX WITH THE ENGINEERED SUBSTRATE MIMIC BEARING A 2-DIMETHYLAMINOMETHYLBENZOATE GROUP | ELECTRON TRANSPORT, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS
5i5k:A (SER1567) to (GLU1589) STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH ECULIZUMAB | COMPLEMENT, FAB, IMMUNE SYSTEM
5i5l:A (SER417) to (GLN471) THE PHOTOSENSORY MODULE (PAS-GAF-PHY) OF THE BACTERIAL PHYTOCHROME AGP1 (ATBPHP1) IN THE PR FORM, CHROMOPHORE MODELLED WITH AN ENDOCYCLIC DOUBLE BOND IN PYRROLE RING A | SIGNALING PROTEIN, BILIN PROTEIN, PHOTOISOMERIZATION, PARALLEL DIMER
4dx8:B (PHE110) to (ALA134) ICAP1 IN COMPLEX WITH KRIT1 N-TERMINUS | PROTEIN-PROTIEN COMPLEX, PTB DOMAIN, NUDIX FOLD, PROTEIN-PROTEIN INTERACTION, MEMBRANE, NUCLEUS, PROTEIN BINDING
4dyk:A (ARG404) to (ARG421) CRYSTAL STRUCTURE OF AN ADENOSINE DEAMINASE FROM PSEUDOMONAS AERUGINOSA PAO1 (TARGET NYSGRC-200449) WITH BOUND ZN | AMIDOHYDROLASE, ADENOSINE DEAMINASE, NYSGRC, STRUCTURAL GENOMICS, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, HYDROLASE
4dyk:B (ARG404) to (ARG421) CRYSTAL STRUCTURE OF AN ADENOSINE DEAMINASE FROM PSEUDOMONAS AERUGINOSA PAO1 (TARGET NYSGRC-200449) WITH BOUND ZN | AMIDOHYDROLASE, ADENOSINE DEAMINASE, NYSGRC, STRUCTURAL GENOMICS, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, HYDROLASE
5i8u:B (GLY44) to (TRP72) CRYSTAL STRUCTURE OF THE RV1700 (MT ADPRASE) E142Q MUTANT | NUDIX, NUDIX HYDROLASE, ADP-RIBOSE HYDROLASE, ADPRASE, ADPR HYDROLASE, HYDROLASE
4e80:C (SER308) to (ASP330) STRUCTURAL BASIS FOR THE ACTIVITY OF A CYTOPLASMIC RNA TERMINAL U- TRANSFERASE | BETA POLYMERASE-LIKE NUCLEOTIDYL TRANSFERASE, TERMINAL URIDINE TRANSFERASE, UTP, RNA, CYTOPLASMIC, TRANSFERASE
4e9i:D (LEU432) to (GLN459) GLUCOSE-6-P DEHYDROGENASE (APO FORM) FROM TRYPANOSOMA CRUZI | DEHYDROGENASE, PENTOSE PHOSPHATE PATHWAY, ALPHA BETA, NAD(P)-BINDING ROSSMANN-LIKE DOMAIN, OXIDOREDUCTASE
4uvn:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 5- AMINO-3-(4-CHLOROPHENYL)-1,2-DIHYDROISOQUINOLIN-1-ONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4uvo:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 5- AMINO-3-(4-METHOXYPHENYL)-1,2-DIHYDROISOQUINOLIN-1-ONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4uvs:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 5- AMINO-3-PENTYL-1,2-DIHYDROISOQUINOLIN-1-ONE | TRANSFERASE, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4uvu:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 1-(( 4-(5-METHYL-1-OXO-1,2-DIHYDROISOQUINOLIN-3-YL)PHENYL) METHYL)PYRROLIDIN-1-IUM | TRANSFERASE, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4uvv:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 3-(4- CHLOROPHENYL)-5-METHYL-1,2-DIHYDROISOQUINOLIN-1-ONE | TRANSFERASE, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4uvx:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 3-(4- CHLOROPHENYL)-5-FLUORO-1,2-DIHYDROISOQUINOLIN-1-ONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4uvz:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 5- AMINO-3-PHENYL-1,2-DIHYDROISOQUINOLIN-1-ONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4uw1:A (SER1277) to (PRO1302) X-RAY CRYSTAL STRUCTURE OF HUMAN TNKS IN COMPLEX WITH A SMALL MOLECULE INHIBITOR | TRANSFERASE, TNKS, INHIBITOR, WNT SIGNALLING
4uw1:D (SER1277) to (PRO1302) X-RAY CRYSTAL STRUCTURE OF HUMAN TNKS IN COMPLEX WITH A SMALL MOLECULE INHIBITOR | TRANSFERASE, TNKS, INHIBITOR, WNT SIGNALLING
4uw1:E (SER1277) to (PRO1302) X-RAY CRYSTAL STRUCTURE OF HUMAN TNKS IN COMPLEX WITH A SMALL MOLECULE INHIBITOR | TRANSFERASE, TNKS, INHIBITOR, WNT SIGNALLING
4uw1:F (SER1277) to (PRO1302) X-RAY CRYSTAL STRUCTURE OF HUMAN TNKS IN COMPLEX WITH A SMALL MOLECULE INHIBITOR | TRANSFERASE, TNKS, INHIBITOR, WNT SIGNALLING
3pvb:B (GLY178) to (GLY199) CRYSTAL STRUCTURE OF (73-244)RIA:C HOLOENZYME OF CAMP-DEPENDENT PROTEIN KINASE | KINASE, RIA HOLOENZYME, TETRAMERIC PROTEIN KINASE A, TRANSFERASE
3q4u:B (SER199) to (ARG218) CRYSTAL STRUCTURE OF THE ACVR1 KINASE DOMAIN IN COMPLEX WITH LDN- 193189 | STRUCTURAL GENOMICS CONSORTIUM, SGC, PROTEIN KINASE, TRANSFERASE
5itu:A (LEU99) to (LEU125) CRYSTAL STRUCTURE OF HUMAN NEIL1(242K) BOUND TO DUPLEX DNA CONTAINING THF | DNA GLYCOSYLASE NEIL1 FPG NEI BASE EXCISION REPAIR, DNA BINDING PROTEIN-DNA COMPLEX
5ixd:A (ALA79) to (VAL97) STRUCTURE OF HUMAN JAK1 FERM/SH2 IN COMPLEX WITH IFN LAMBDA RECEPTOR | JAK KINASE, JAK1, IFNLR1, INTERFERON, CYTOKINE
3qbh:A (TYR342) to (PRO373) STRUCTURE BASED DESIGN, SYNTHESIS AND SAR OF CYCLIC HYDROXYETHYLAMINE (HEA) BACE-1 INHIBITORS | ENZYME INHIBITOR COMPLEX, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3qbh:C (TYR342) to (PRO373) STRUCTURE BASED DESIGN, SYNTHESIS AND SAR OF CYCLIC HYDROXYETHYLAMINE (HEA) BACE-1 INHIBITORS | ENZYME INHIBITOR COMPLEX, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5j6f:A (THR105) to (MET123) CRYSTAL STRUCTURE OF DAH7PS-CM COMPLEX FROM GEOBACILLUS SP. WITH PREPHENATE | TIM BARREL, DAH7PS, DAH7P, TRANSFERASE, LYASE, ISOMERASE
4v1a:b (PRO172) to (PRO195) STRUCTURE OF THE LARGE SUBUNIT OF THE MAMMALIAN MITOCHONDRIAL RIBOSOME, PART 2 OF 2 | RIBOSOME, TRANSLATION, LARGE RIBOSOMAL SUBUNIT, MITORIBOSOME, MAMMALIAN MITOCHONDRIAL RIBOSOME, CRYO-EM
4fd9:A (LEU3) to (SER26) CRYSTAL STRUCTURE OF THE THIRD BETA-GAMMA-CRYSTALLIN DOMAIN OF CRYBG3 (BETAGAMMA-CRYSTALLIN DOMAIN-CONTAINING PROTEIN 3) FROM MUS MUSCULUS | NON-LENS VERTEBRATE BETA-GAMMA-CRYSTALLIN, BRAIN, STRUCTURAL PROTEIN
4fd9:B (LEU3) to (SER26) CRYSTAL STRUCTURE OF THE THIRD BETA-GAMMA-CRYSTALLIN DOMAIN OF CRYBG3 (BETAGAMMA-CRYSTALLIN DOMAIN-CONTAINING PROTEIN 3) FROM MUS MUSCULUS | NON-LENS VERTEBRATE BETA-GAMMA-CRYSTALLIN, BRAIN, STRUCTURAL PROTEIN
3qpy:A (MET1) to (ILE22) CRYSTAL STRUCTURE OF A MUTANT (K57A) OF 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3qpy:B (MET1) to (GLY20) CRYSTAL STRUCTURE OF A MUTANT (K57A) OF 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3qpy:C (MET1) to (GLY20) CRYSTAL STRUCTURE OF A MUTANT (K57A) OF 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3qpy:D (MET1) to (ILE22) CRYSTAL STRUCTURE OF A MUTANT (K57A) OF 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3qq0:A (MET1) to (ILE22) CRYSTAL STRUCTURE OF A DELETION MUTANT (N59) OF 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3qq0:C (MET1) to (GLY20) CRYSTAL STRUCTURE OF A DELETION MUTANT (N59) OF 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3qq0:D (MET1) to (GLY20) CRYSTAL STRUCTURE OF A DELETION MUTANT (N59) OF 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3qq1:C (MET1) to (ILE22) CRYSTAL STRUCTURE OF A DOUBLE MUTANT [A58P, DEL(N59)] OF 3-DEOXY-D- MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4fdh:C (LEU390) to (PHE406) STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH FADROZOLE | CYTOCHROME P450, CYP11B2, ALDOSTERONE SYNTHASE, MONOOXYGENASE, HEME PROTEIN, MINERALOCORTICOID, INHIBITOR, MITOCHONDRIA, MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3qsq:A (TYR519) to (ILE550) CRYSTAL STRUCTURE OF THE PROJECTION DOMAIN OF THE HUMAN ASTROVIRUS CAPSID PROTEIN | RECEPTOR BINDING DOMAIN, ASTROVIRUS CAPSID, VIRAL PROTEIN
3r1a:B (ASP374) to (VAL391) CLOSED CRYSTAL STRUCTURE OF CYTOCHROME P450 2B4 COVALENTLY BOUND TO THE MECHANISM-BASED INACTIVATOR TERT-BUTYLPHENYLACETYLENE | CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, T302 COVALENTLY LINKED TO TERT-BUTYLPHENYLACETYLENE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3r1a:C (ASP374) to (VAL391) CLOSED CRYSTAL STRUCTURE OF CYTOCHROME P450 2B4 COVALENTLY BOUND TO THE MECHANISM-BASED INACTIVATOR TERT-BUTYLPHENYLACETYLENE | CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, T302 COVALENTLY LINKED TO TERT-BUTYLPHENYLACETYLENE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3r1a:D (LYS373) to (VAL391) CLOSED CRYSTAL STRUCTURE OF CYTOCHROME P450 2B4 COVALENTLY BOUND TO THE MECHANISM-BASED INACTIVATOR TERT-BUTYLPHENYLACETYLENE | CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, T302 COVALENTLY LINKED TO TERT-BUTYLPHENYLACETYLENE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3r1a:G (LYS373) to (VAL391) CLOSED CRYSTAL STRUCTURE OF CYTOCHROME P450 2B4 COVALENTLY BOUND TO THE MECHANISM-BASED INACTIVATOR TERT-BUTYLPHENYLACETYLENE | CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, T302 COVALENTLY LINKED TO TERT-BUTYLPHENYLACETYLENE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3r1b:C (ASP374) to (VAL391) OPEN CRYSTAL STRUCTURE OF CYTOCHROME P450 2B4 COVALENTLY BOUND TO THE MECHANISM-BASED INACTIVATOR TERT-BUTYLPHENYLACETYLENE | CYTOCHROME P450 2B4, MONOOXYGENASE, MEMBRANE PROTEIN, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
4fm8:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE WITH COMPOUND 12A | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4w8s:A (GLY205) to (GLN223) CRYSTAL STRUCTURE OF TRUNCATED HEMOLYSIN A Q125S/Y134S FROM P. MIRABILIS AT 1.5 ANGSTROMS RESOLUTION | HEMOLYSIN, TWO PARTNER SECRETION, BETA SOLENOID, BETA HELIX, TOXIN
4w99:B (MET23) to (GLY64) APO-STRUCTURE OF THE Y79F,W322E-DOUBLE MUTANT OF ETR1P | REDUCTASE, MITOCHONDRIAL FATTY ACID SYNTHESIS, OXIDOREDUCTASE
4frj:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH AMINOOXAZOLINE XANTHENE 9L | MEMBRANE PROTEIN, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, HYDROLASE- INHIBITOR COMPLEX
4frk:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH AMINOOXAZOLINE XANTHENE 11A | MEMBRANE PROTEIN, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, HYDROLASE- INHIBITOR COMPLEX
4frs:A (TYR403) to (PRO434) STRUCTURE OF BACE IN COMPLEX WITH (S)-4-(3-CHLORO-5-(5-(PROP-1-YN-1- YL)PYRIDIN-3-YL)THIOPHEN-2-YL)-1,4-DIMETHYL-6-OXOTETRAHYDROPYRIMIDIN- 2(1H)-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4frs:B (TYR403) to (PRO434) STRUCTURE OF BACE IN COMPLEX WITH (S)-4-(3-CHLORO-5-(5-(PROP-1-YN-1- YL)PYRIDIN-3-YL)THIOPHEN-2-YL)-1,4-DIMETHYL-6-OXOTETRAHYDROPYRIMIDIN- 2(1H)-IMINIUM | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4fs4:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO (S)-4-(3'-METHOXY-[1,1'-BIPHENYL]-3-YL)-1, 4-DIMETHYL-6-OXOTETRAHYDROPYRIMIDIN-2(1H)-IMINIUM | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4fs4:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO (S)-4-(3'-METHOXY-[1,1'-BIPHENYL]-3-YL)-1, 4-DIMETHYL-6-OXOTETRAHYDROPYRIMIDIN-2(1H)-IMINIUM | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4fsl:A (TYR390) to (PRO421) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-DB-MUT) COMPLEX WITH N-(N-(4- ACETAMIDO-3-CHLORO-5-METHYLBENZYL) CARBAMIMIDOYL)-3-(4- METHOXYPHENYL)-5-METHYL-4-ISOTHIAZOLECARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2, BASE, ASPARTIC PROTEASE, HYDROLASE-INHIBITOR COMPLEX
4fsl:B (TYR390) to (PRO421) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-DB-MUT) COMPLEX WITH N-(N-(4- ACETAMIDO-3-CHLORO-5-METHYLBENZYL) CARBAMIMIDOYL)-3-(4- METHOXYPHENYL)-5-METHYL-4-ISOTHIAZOLECARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2, BASE, ASPARTIC PROTEASE, HYDROLASE-INHIBITOR COMPLEX
4fsl:D (TYR390) to (PRO421) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-DB-MUT) COMPLEX WITH N-(N-(4- ACETAMIDO-3-CHLORO-5-METHYLBENZYL) CARBAMIMIDOYL)-3-(4- METHOXYPHENYL)-5-METHYL-4-ISOTHIAZOLECARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2, BASE, ASPARTIC PROTEASE, HYDROLASE-INHIBITOR COMPLEX
4fsl:E (TYR390) to (PRO421) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-DB-MUT) COMPLEX WITH N-(N-(4- ACETAMIDO-3-CHLORO-5-METHYLBENZYL) CARBAMIMIDOYL)-3-(4- METHOXYPHENYL)-5-METHYL-4-ISOTHIAZOLECARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2, BASE, ASPARTIC PROTEASE, HYDROLASE-INHIBITOR COMPLEX
5jon:B (VAL561) to (GLY581) CRYSTAL STRUCTURE OF THE UNLIGANDED FORM OF HCN2 CNBD | HCN CHANNELS, CYCLIC NUCLEOTIDE REGULATED CHANNELS, CYCLIC NUCLEOTIDE BINDING DOMAIN, TRANSPORT PROTEIN
5jpn:C (ASP1635) to (LYS1655) STRUCTURE OF HUMAN COMPLEMENT C4 REBUILT USING IMDFF | COMPLEMENT, IMMUNE SYSTEM, BLOOD
5jq9:B (SER0) to (VAL23) YERSINIA PESTIS DHPS WITH PTERINE-SULFA CONJUGATE COMPOUND 16 | DIHYDROPTEROATE SYNTHESIS, ANTIBIOTIC, PTERINE-SULFA CONJUGATES, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4fzh:D (LEU476) to (ALA504) STRUCTURE OF THE ULSTER STRAIN NEWCASTLE DISEASE VIRUS HEMAGGLUTININ- NEURAMINIDASE REVEALS AUTO-INHIBITORY INTERACTIONS ASSOCIATED WITH LOW VIRULENCE | HYDROLASE
5k59:D (SER241) to (PRO283) CRYSTAL STRUCTURE OF LUKGH FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH A NEUTRALISING ANTIBODY | TOXIN NEUTRALIZING MONOCLONAL ANTIBODY, CONFORMATIONAL EPITOPE, X-RAY CRYSTAL STRUCTURE, IMMUNE SYSTEM
4g7z:C (ARG408) to (GLU463) CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS TRANSCRIPTION INITIATION COMPLEX CONTAINING 5-BRU AT TEMPLATE-STRAND POSITION +1 | PROTEIN-DNA COMPLEX, TRANSCRIPTION INITIATION COMPLEX, RNAP-PROMOTER COMPLEX, RNAP-PROMOTER OPEN COMPLEX, OPEN COMPLEX, RPO, RNA POLYMERASE, TRANSCRIPTION INITIATION, TRANSCRIPTION INITIATION FACTOR SIGMA A, PROMOTER DNA, NUCLEOID, TRANSCRIPTION, TRANSFERASE- DNA COMPLEX
5kbf:B (ASN356) to (GLY376) CAMP BOUND PFPKA-R (141-441) | PLASMODIUM FALCIPARUM, PKA, PROTEIN KINASE A, CAMP, CBD, CYCLIC NUCLEOTIDE BINDING, CNB, REGULATORY DOMAIN, R, TRANSFERASE
4gbd:A (ARG404) to (ARG421) CRYSTAL STRUCTURE OF ADENOSINE DEAMINASE FROM PSEUDOMONAS AERUGINOSA PAO1 WITH BOUND ZN AND METHYLTHIO-COFORMYCIN | DEAMINASE, METHYLTIHOADENOSINE, LYASE
4gbd:B (ARG404) to (ARG421) CRYSTAL STRUCTURE OF ADENOSINE DEAMINASE FROM PSEUDOMONAS AERUGINOSA PAO1 WITH BOUND ZN AND METHYLTHIO-COFORMYCIN | DEAMINASE, METHYLTIHOADENOSINE, LYASE
4gfs:B (MET1) to (LYS25) 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE 3-DEHYDROQUINATE DEHYDRATASE (AROD) FROM SALMONELLA TYPHIMURIUM LT2 WITH NICKEL BOUND AT ACTIVE SITE | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, TIM BARREL, LYASE
4gid:A (TYR390) to (PRO421) STRUCTURE OF BETA-SECRETASE COMPLEXED WITH INHIBITOR | ASPARTIC PROTEASE, BETA SECRETASE, APP, BACE, A-BETA, PROTEASE, MEMAPSIN, ALZHEIMER, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4gid:C (TYR390) to (PRO421) STRUCTURE OF BETA-SECRETASE COMPLEXED WITH INHIBITOR | ASPARTIC PROTEASE, BETA SECRETASE, APP, BACE, A-BETA, PROTEASE, MEMAPSIN, ALZHEIMER, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4gid:D (TYR390) to (PRO421) STRUCTURE OF BETA-SECRETASE COMPLEXED WITH INHIBITOR | ASPARTIC PROTEASE, BETA SECRETASE, APP, BACE, A-BETA, PROTEASE, MEMAPSIN, ALZHEIMER, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5kvi:A (ASN241) to (ILE258) CRYSTAL STRUCTURE OF MONOMERIC HUMAN APOPTOSIS-INDUCING FACTOR WITH E413A/R422A/R430A MUTATIONS | OXIDOREDUCTASE, FLAVOPROTEIN, MITOCHONDRIA CELL DEATH
5l92:B (GLU298) to (TRP316) THE 2.1 A CRYSTAL STRUCTURE OF CYP109E1 FROM BACILLUS MEGATERIUM IN COMPLEX WITH CORTICOSTERONE | BACILLUS, BACTERIAL PROTEINS, BINDING SITES, CATALYSIS, CORTICOSTERONE, CYTOCHROME P-450 ENZYME SYSTEM, CYTOCHROME P450, HYDROXYLATION, ESCHERICHIA COLI, HEME, LIGANDS, MOLECULAR STRUCTURE, OXIDATION-REDUCTION, OXYGEN, PROTEIN, PROTEIN STRUCTURE, SECONDARY, STEROIDS, SUBSTRATE SPECIFICITY, OXIDOREDUCTASE
5l94:A (GLU298) to (TRP316) THE 2.25 A CRYSTAL STRUCTURE OF CYP109E1 FROM BACILLUS MEGATERIUM IN COMPLEX WITH TESTOSTERONE | BACILLUS, BACTERIAL PROTEINS, BINDING SITES, CATALYSIS, CYTOCHROME P- 450 ENZYME SYSTEM, CYTOCHROME P450, HYDROXYLATION, ESCHERICHIA COLI, HEME, LIGANDS, MOLECULAR STRUCTURE, OXIDATION-REDUCTION, OXYGEN, PROTEIN, PROTEIN STRUCTURE, SECONDARY, STEROIDS, SUBSTRATE SPECIFICITY, TESTOSTERONE, OXIDOREDUCTASE
5szs:A (THR169) to (ASN198) GLYCAN SHIELD AND EPITOPE MASKING OF A CORONAVIRUS SPIKE PROTEIN OBSERVED BY CRYO-ELECTRON MICROSCOPY | CORONAVIRUS, VIRAL FUSION PROTEIN, VACCINE, NL63, VIRAL PROTEIN
5szs:B (THR169) to (ASN198) GLYCAN SHIELD AND EPITOPE MASKING OF A CORONAVIRUS SPIKE PROTEIN OBSERVED BY CRYO-ELECTRON MICROSCOPY | CORONAVIRUS, VIRAL FUSION PROTEIN, VACCINE, NL63, VIRAL PROTEIN
5szs:C (THR169) to (ASN198) GLYCAN SHIELD AND EPITOPE MASKING OF A CORONAVIRUS SPIKE PROTEIN OBSERVED BY CRYO-ELECTRON MICROSCOPY | CORONAVIRUS, VIRAL FUSION PROTEIN, VACCINE, NL63, VIRAL PROTEIN
5t5i:A (ALA494) to (HIS514) TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE FROM METHANOTHERMOBACTER WOLFEII, ORTHORHOMBIC FORM AT 1.9 A | CO2 FIXATION, METALLOHYDROLASE, FORMATE DEHYDROGENASE, TUNGSTOPTERIN, METHANOGENESIS, GREEN HOUSE GAS, METHANOTHERMOBACTER WOLFEII, IRON SULFUR CLUSTER, FERREDOXIN, BETA HELICOIDAL, CHANNEL, FORMATE, CO2, METHANOFURAN, FORMYLMETHANOFURAN, NANOMACHINE, BINUCLEAR CENTER, TUNGSTEN, GATE, COUPLING, ENZYME, ANAEROBIC, CARBOXYLYSINE, OXIDOREDUCTASE
5t5i:I (ALA494) to (HIS514) TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE FROM METHANOTHERMOBACTER WOLFEII, ORTHORHOMBIC FORM AT 1.9 A | CO2 FIXATION, METALLOHYDROLASE, FORMATE DEHYDROGENASE, TUNGSTOPTERIN, METHANOGENESIS, GREEN HOUSE GAS, METHANOTHERMOBACTER WOLFEII, IRON SULFUR CLUSTER, FERREDOXIN, BETA HELICOIDAL, CHANNEL, FORMATE, CO2, METHANOFURAN, FORMYLMETHANOFURAN, NANOMACHINE, BINUCLEAR CENTER, TUNGSTEN, GATE, COUPLING, ENZYME, ANAEROBIC, CARBOXYLYSINE, OXIDOREDUCTASE
5t5m:A (ALA494) to (HIS514) TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE FROM METHANOTHERMOBACTER WOLFEII, TRIGONAL FORM AT 2.5 A. | CO2 FIXATION, METALLOHYDROLASE, FORMATE DEHYDROGENASE, TUNGSTOPTERIN, METHANOGENESIS, GREEN HOUSE GAS, METHANOTHERMOBACTER WOLFEII, IRON SULFUR CLUSTER, FERREDOXIN, BETA HELICOIDAL, CHANNEL, FORMATE, CO2, METHANOFURAN, FORMYLMETHANOFURAN, NANOMACHINE, BINUCLEAR CENTER, TUNGSTEN, GATE, COUPLING, ENZYME, ANAEROBIC, CARBOXYLYSINE, OXIDOREDUCTASE
5tol:A (TYR390) to (PRO421) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 COMPLEXED WITH N- (3-((4AS,7AS)-2-AMINO-4,4A,5,6-TETRAHYDRO-7AH-FURO[2,3-D][1, 3]THIAZIN-7A-YL)-4-FLUOROPHENYL)-5-BROMO-2-PYRIDINECARBOXAMIDE | ASPARTYL PROTEASE, BACE1, KIAA1149, ASP2, FLJ90568, BACE, HSPC104, HYDROLASE
9rub:B (ALA348) to (GLY369) CRYSTAL STRUCTURE OF ACTIVATED RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE COMPLEXED WITH ITS SUBSTRATE, RIBULOSE-1,5- BISPHOSPHATE | LYASE(CARBON-CARBON)
4guj:B (LYS2) to (LYS25) 1.50 ANGSTROM CRYSTAL STRUCTURE OF THE SALMONELLA ENTERICA 3- DEHYDROQUINATE DEHYDRATASE (AROD) IN COMPLEX WITH SHIKIMATE | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, TIM BARREL, LYASE
2ohr:A (TYR342) to (PRO373) X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 6A | ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, TRANSMEMBRANE, ZYMOGEN
1aey:A (TYR13) to (ASN35) ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, SOLUTION NMR, 15 STRUCTURES | CYTOSKELETON, CAPPING PROTEIN, CALCIUM-BINDING, DUPLICATION, REPEAT, SH3 DOMAIN
3rsv:A (TYR342) to (PRO373) STRUCTURE OF BACE-1 (BETA-SECRETASE) IN COMPLEX WITH (R)-3-(2-AMINO-6- O-TOLYLQUINOLIN-3-YL)-N-((R)-2,2-DIMETHYLTETRAHYDRO-2H-PYRAN-4-YL)-2- METHYLPROPANAMIDE | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4h5i:A (TYR15) to (LEU42) CRYSTAL STRUCTURE OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR SEC12 (P1 FORM) | COPII VESICLE BUDDING, POTASSIUM BINDING SITE, BETA PROPELLER, PROTEIN TRANSPORT
4h5i:B (TYR15) to (LEU42) CRYSTAL STRUCTURE OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR SEC12 (P1 FORM) | COPII VESICLE BUDDING, POTASSIUM BINDING SITE, BETA PROPELLER, PROTEIN TRANSPORT
4h5j:A (TYR15) to (LEU42) CRYSTAL STRUCTURE OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR SEC12 (P64 FORM) | COPII VESICLE BUDDING, POTASSIUM BINDING SITE, BETA PROPELLER, PROTEIN TRANSPORT
2b9v:F (THR443) to (ASP473) ACETOBACTER TURBIDANS ALPHA-AMINO ACID ESTER HYDROLASE | CATALYTIC TRIAD, ALPHA/BETA-HYDROLASE, HYDROLASE
4i02:B (GLY46) to (GLY72) STRUCTURE OF THE MUTANT CATABOLITE GENE ACTIVATOR PROTEIN V140A | DNA BINDING, TRANSCRIPTION
1c5e:A (ALA29) to (TYR75) BACTERIOPHAGE LAMBDA HEAD PROTEIN D | BACTERIOPHAGE LAMBDA, HEAD PROTEIN D, PROTEIN CRYSTAL STRUCTURE, VIRUS ASSEMBLY, PHAGE DISPLAY, VIRAL PROTEIN
1c5e:B (ALA29) to (PHE74) BACTERIOPHAGE LAMBDA HEAD PROTEIN D | BACTERIOPHAGE LAMBDA, HEAD PROTEIN D, PROTEIN CRYSTAL STRUCTURE, VIRUS ASSEMBLY, PHAGE DISPLAY, VIRAL PROTEIN
1c5e:C (ALA29) to (TYR75) BACTERIOPHAGE LAMBDA HEAD PROTEIN D | BACTERIOPHAGE LAMBDA, HEAD PROTEIN D, PROTEIN CRYSTAL STRUCTURE, VIRUS ASSEMBLY, PHAGE DISPLAY, VIRAL PROTEIN
2c1w:B (GLY196) to (PRO225) THE STRUCTURE OF XENDOU: A SPLICING INDEPENDENT SNORNA PROCESSING ENDORIBONUCLEASE | NUCLEASE, SNORNA, ENDORIBONUCLEASE, SPLICING INDEPENDENT PROCESSING
2ptk:A (ASP117) to (PRO139) CHICKEN SRC TYROSINE KINASE | TYROSINE-PROTEIN KINASE, SRC, SH2, SH3
4xkx:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH 2-AMINOOXAZOLINE 3- AZAXANTHENE INHIBITOR 28 | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4i9i:C (SER1277) to (LYS1312) CRYSTAL STRUCTURE OF TANKYRASE 1 WITH COMPOUND 4 | TANKYRASE, PARP, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4i9i:D (SER1277) to (LYS1312) CRYSTAL STRUCTURE OF TANKYRASE 1 WITH COMPOUND 4 | TANKYRASE, PARP, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2c6h:B (GLU300) to (LEU319) CRYSTAL STRUCTURE OF YC-17-BOUND CYTOCHROME P450 PIKC (CYP107L1) | OXIDOREDUCTASE, CYTOCHROME P450, PIKC, CYP107L1, MACROLIDE MONOOXYGENASE, ANTIBIOTIC BIOSYNTHESIS, HEME, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE ANTIBIOTIC BIOSYNTHESIS
2q15:A (TYR342) to (PRO373) STRUCTURE OF BACE COMPLEXED TO COMPOUND 3A | BACE INHIBITOR COMPLEX, HYDROLASE
3stc:A (MET1) to (ILE22) CRYSTAL STRUCTURE OF LOOP 7 TRUNCATED MUTANT OF 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3stc:C (MET1) to (GLY20) CRYSTAL STRUCTURE OF LOOP 7 TRUNCATED MUTANT OF 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3stc:D (MET1) to (ILE22) CRYSTAL STRUCTURE OF LOOP 7 TRUNCATED MUTANT OF 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
2q6n:A (ASP374) to (VAL391) STRUCTURE OF CYTOCHROME P450 2B4 WITH BOUND 1-(4- CHOLOROPHENYL)IMIDAZOLE | P450, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2
2q6n:D (ASP374) to (VAL391) STRUCTURE OF CYTOCHROME P450 2B4 WITH BOUND 1-(4- CHOLOROPHENYL)IMIDAZOLE | P450, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2
2q6n:E (ASP374) to (VAL391) STRUCTURE OF CYTOCHROME P450 2B4 WITH BOUND 1-(4- CHOLOROPHENYL)IMIDAZOLE | P450, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2
2q6n:G (LYS373) to (PRO390) STRUCTURE OF CYTOCHROME P450 2B4 WITH BOUND 1-(4- CHOLOROPHENYL)IMIDAZOLE | P450, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2
2ca0:A (GLU300) to (LEU319) CRYSTAL STRUCTURE OF YC-17-BOUND CYTOCHROME P450 PIKC ( CYP107L1) | OXIDOREDUCTASE, CYTOCHROME P450, PIKC, YC-17, MACROLIDE MONOOXYGENASE, ANTIBIOTIC BIOSYNTHESIS, HEME, IRON, METAL-BINDING
3fyo:A (MET1) to (ILE22) CRYSTAL STRUCTURE OF THE TRIPLE MUTANT (N23C/D247E/P249A) OF 3-DEOXY- D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3fyo:B (MET1) to (GLY20) CRYSTAL STRUCTURE OF THE TRIPLE MUTANT (N23C/D247E/P249A) OF 3-DEOXY- D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3fyo:C (MET1) to (GLY20) CRYSTAL STRUCTURE OF THE TRIPLE MUTANT (N23C/D247E/P249A) OF 3-DEOXY- D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
3fyo:D (MET1) to (ILE22) CRYSTAL STRUCTURE OF THE TRIPLE MUTANT (N23C/D247E/P249A) OF 3-DEOXY- D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LYASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4xtz:A (GLY66) to (ARG89) MYCOBACTERIUM TUBERCULOSIS BIOTIN LIGASE COMPLEXED WITH BISUBSTRATE INHIBITOR 69 THAT HAS A FLUORINE IN PLACE OF THE RIBOSE 2'OH | BIOTIN-PROTEIN LIGASE, BISUBSTRATE INHIBITOR, LIGASE-LIGASE INHIBITOR COMPLEX
3gde:A (VAL485) to (GLN505) THE CLOSED CONFORMATION OF ATP-DEPENDENT DNA LIGASE FROM ARCHAEOGLOBUS FULGIDUS | ATP-DEPENDENT DNA LIGASE, DNA-BINDING DOMAIN, ADENYLATION DOMAIN, OB-FOLD DOMAIN, ATP-BINDING, CELL CYCLE, CELL DIVISION, DNA DAMAGE, DNA RECOMBINATION, DNA REPAIR, DNA REPLICATION, LIGASE, NUCLEOTIDE-BINDING
2qqp:G (SER340) to (MET359) CRYSTAL STRUCTURE OF AUTHENTIC PROVIDENCE VIRUS | VIRUS, CAPSID, COAT PROTEIN, PROTEIN-RNA COMPLEX, BETA BARREL, IG- LIKE DOMAIN, TETRAVIRUS, TETRAVIRIDAE, ICOSAHEDRAL VIRUS, QUASIEQUIVALENCE, AUTO-CATALYTIC CLEAVAGE, AUTO PROTEOLYSIS
2dbu:A (GLY97) to (THR150) CRYSTAL STRUCTURE OF GAMMA-GLUTAMYLTRANSPEPTIDASE FROM ESCHERICHIA COLI | GAMMA-GLUTAMYLTRANSFERASE, GGT, GAMMA-GTP, GLUTATHIONE
2dbu:C (GLY97) to (THR150) CRYSTAL STRUCTURE OF GAMMA-GLUTAMYLTRANSPEPTIDASE FROM ESCHERICHIA COLI | GAMMA-GLUTAMYLTRANSFERASE, GGT, GAMMA-GTP, GLUTATHIONE
2dbx:A (GLY97) to (THR150) CRYSTAL STRUCTURE OF GAMMA-GLUTAMYLTRANSPEPTIDASE FROM ESCHERICHIA COLI COMPLEXED WITH L-GLUTAMATE | GAMMA-GLUTAMYLTRANSFERASE, GGT, GAMMA-GTP, GLUTATHIONE, TRANSFERASE
2dbx:C (GLY97) to (THR150) CRYSTAL STRUCTURE OF GAMMA-GLUTAMYLTRANSPEPTIDASE FROM ESCHERICHIA COLI COMPLEXED WITH L-GLUTAMATE | GAMMA-GLUTAMYLTRANSFERASE, GGT, GAMMA-GTP, GLUTATHIONE, TRANSFERASE
2dg5:A (GLY97) to (THR150) CRYSTAL STRUCTURE OF GAMMA-GLUTAMYL TRANSPEPTIDASE FROM ESCHERICHIA COLI IN COMPLEX WITH HYDROLYZED GLUTATHIONE | GAMMA-GLUTAMYLTRANSFERASE, GGT, GAMMA-GT, GLUTATHIONE, TRANSFERASE
2dg5:C (GLY97) to (THR150) CRYSTAL STRUCTURE OF GAMMA-GLUTAMYL TRANSPEPTIDASE FROM ESCHERICHIA COLI IN COMPLEX WITH HYDROLYZED GLUTATHIONE | GAMMA-GLUTAMYLTRANSFERASE, GGT, GAMMA-GT, GLUTATHIONE, TRANSFERASE
1q3r:C (GLU348) to (GLY378) CRYSTAL STRUCTURE OF THE CHAPERONIN FROM THERMOCOCCUS STRAIN KS-1 (NUCLEOTIDE-FREE FORM OF SINGLE MUTANT) | CHAPERONE, CHAPERONIN, THERMOSOME
1q7m:A (ALA302) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (METH) FROM THERMOTOGA MARITIMA (OXIDIZED, MONOCLINIC) | HOMOCYSTEINE, METHIONINE, FOLATE, COBALAMIN, VITAMIN B12, TRANSFERASE
1q7m:B (ALA302) to (ARG321) COBALAMIN-DEPENDENT METHIONINE SYNTHASE (METH) FROM THERMOTOGA MARITIMA (OXIDIZED, MONOCLINIC) | HOMOCYSTEINE, METHIONINE, FOLATE, COBALAMIN, VITAMIN B12, TRANSFERASE
2dxl:A (THR200) to (PRO220) GLYCEROPHOSPHODIESTERASE FROM ENTEROBACTER AEROGENES | DOMAIN-SWAPPING, BETA-SHEET EXTENSION, METALLOENZYME, DISULFIDE, ALPHA/BETA SANDWICH, HYDROLASE
2dxl:B (THR200) to (PRO220) GLYCEROPHOSPHODIESTERASE FROM ENTEROBACTER AEROGENES | DOMAIN-SWAPPING, BETA-SHEET EXTENSION, METALLOENZYME, DISULFIDE, ALPHA/BETA SANDWICH, HYDROLASE
2rg0:B (GLY191) to (VAL215) CRYSTAL STRUCTURE OF CELLOBIOHYDROLASE FROM MELANOCARPUS ALBOMYCES COMPLEXED WITH CELLOTETRAOSE | HYDROLASE, GLYCOSIDASE
3h0i:A (ASP118) to (ASP142) HUMAN FYN SH3 DOMAIN R96I MUTANT, CRYSTAL FORM II | BETA BARREL, TRANSFERASE
2e0y:A (GLY97) to (THR150) CRYSTAL STRUCTURE OF THE SAMARIUM DERIVATIVE OF MATURE GAMMA- GLUTAMYLTRANSPEPTIDASE FROM ESCHERICHIA COLI | GAMMA-GLUTAMYLTRANSFERASE, GGT, GAMMA-GT, GLUTATHIONE, TRANSFERASE
2e0y:C (GLY97) to (THR150) CRYSTAL STRUCTURE OF THE SAMARIUM DERIVATIVE OF MATURE GAMMA- GLUTAMYLTRANSPEPTIDASE FROM ESCHERICHIA COLI | GAMMA-GLUTAMYLTRANSFERASE, GGT, GAMMA-GT, GLUTATHIONE, TRANSFERASE
1qk2:A (GLY355) to (LYS395) WILD TYPE CEL6A WITH A NON-HYDROLYSABLE CELLOTETRAOSE | HYDROLASE, GLYCOSIDASE, GLYCOPROTEIN
1qk2:B (GLY355) to (LYS395) WILD TYPE CEL6A WITH A NON-HYDROLYSABLE CELLOTETRAOSE | HYDROLASE, GLYCOSIDASE, GLYCOPROTEIN
3h1m:A (GLU349) to (GLY370) CRYSTAL STRUCTURE OF MANNOSE 6-PHOSPHATE ISOMERASE (HOLO; ZINC BOUND) | METAL BINDING PROTEIN ZINC BOUND, CUPIN DOMAIN, ISOMERASE, METAL- BINDING
3tyb:B (ASP4) to (THR29) DIHYDROPTEROATE SYNTHASE IN COMPLEX WITH PHBA AND DHP+ | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TIM BARREL, TRANSFERASE
4jtf:A (MET1) to (GLY20) CRYSTAL STRUCTURE OF F114R MUTANT OF 3-DEOXY-D-MANNO-OCTULOSONATE 8- PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4jtf:B (MET1) to (GLY20) CRYSTAL STRUCTURE OF F114R MUTANT OF 3-DEOXY-D-MANNO-OCTULOSONATE 8- PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
4jtf:D (MET1) to (ILE22) CRYSTAL STRUCTURE OF F114R MUTANT OF 3-DEOXY-D-MANNO-OCTULOSONATE 8- PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8 KDOPS, KDO8PS, TIM BARREL, BIOSYNTHESIS, TRANSFERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
2eay:B (GLY210) to (ARG232) CRYSTAL STRUCTURE OF BIOTIN PROTEIN LIGASE FROM AQUIFEX AEOLICUS | BIOTIN BIOSYNTHESIS, DIMER, X-RAY DIFFRACTION, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LIGASE
3ua9:B (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH A SELECTIVE INHIBITOR | PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP-RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2v3n:A (ARG354) to (GLY377) CRYSTALLOGRAPHIC ANALYSIS OF UPPER AXIAL LIGAND SUBSTITUTIONS IN COBALAMIN BOUND TO TRANSCOBALAMIN | TRANSPORT PROTEIN, COBALT, TRANSPORT, GLYCOPROTEIN, ION TRANSPORT, VITAMIN B12 TRANSPORT PROTEIN, COBALT TRANSPORT, BETA LIGAND SUBSTITUTION
4yry:D (ILE341) to (PRO370) INSIGHTS INTO FLAVIN-BASED ELECTRON BIFURCATION VIA THE NADH-DEPENDENT REDUCED FERREDOXIN-NADP OXIDOREDUCTASE STRUCTURE | OXIDOREDUCTASE
2va7:A (TYR342) to (PRO373) X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 27 | BASE, ZYMOGEN, PROTEASE, MEMBRANE, HYDROLASE, ALZHEIMER'S DISEASE, ALTERNATIVE SPLICING, MEMAPSIN 2, GLYCOPROTEIN, TRANSMEMBRANE, BETA-SECRETASE, ASPARTYL PROTEASE, ASPARTIC PROTEASE
1fwl:B (PHE150) to (ASN178) CRYSTAL STRUCTURE OF HOMOSERINE KINASE | KINASE, TRANSFERASE
1g83:B (ASP118) to (PRO140) CRYSTAL STRUCTURE OF FYN SH3-SH2 | BETA BARREL, ANTIPARALLEL BETA SHEET, ALPHA HELIX, 3-10 HELIX, TRANSFERASE
4khw:A (THR7) to (GLU30) TERNARY COMPLEX OF RB69 MUTANT L415F WITH RIBONUCLEOTIDE AT -2 POSITION | RIBONUCLEOTIDE, TRANSFERASE-DNA COMPLEX
2vkm:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF GRL-8234 BOUND TO BACE (BETA-SECRETASE) | ALTERNATIVE SPLICING, ASPARTYL PROTEASE, ASPARTIC PROTEASE, GLYCOPROTEIN, TRANSMEMBRANE, BETA SECRETASE, APP, BACE, A-BETA, X- RAY, ZYMOGEN, MEMBRANE, PROTEASE, MEMAPSIN, HYDROLASE, ALZHEIMER, DRUG DESIGN
2vkm:C (TYR342) to (PRO373) CRYSTAL STRUCTURE OF GRL-8234 BOUND TO BACE (BETA-SECRETASE) | ALTERNATIVE SPLICING, ASPARTYL PROTEASE, ASPARTIC PROTEASE, GLYCOPROTEIN, TRANSMEMBRANE, BETA SECRETASE, APP, BACE, A-BETA, X- RAY, ZYMOGEN, MEMBRANE, PROTEASE, MEMAPSIN, HYDROLASE, ALZHEIMER, DRUG DESIGN
2vkm:D (TYR342) to (PRO373) CRYSTAL STRUCTURE OF GRL-8234 BOUND TO BACE (BETA-SECRETASE) | ALTERNATIVE SPLICING, ASPARTYL PROTEASE, ASPARTIC PROTEASE, GLYCOPROTEIN, TRANSMEMBRANE, BETA SECRETASE, APP, BACE, A-BETA, X- RAY, ZYMOGEN, MEMBRANE, PROTEASE, MEMAPSIN, HYDROLASE, ALZHEIMER, DRUG DESIGN
4z89:B (ASP1325) to (GLY1354) SH3-II OF DROSOPHILA RIM-BINDING PROTEIN BOUND TO A CACOPHONY DERIVED PEPTIDE | SYNAPSE, ACTIVE ZONE, SH3 DOMAIN, RIM-BINDING PROTEIN, CACOPHONY PEPTIDE
3hw1:A (TYR342) to (PRO373) STRUCTURE OF BACE (BETA SECRETASE) IN COMPLEX WITH LIGAND EV2 | PROTEASE, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, AMYLOID PRECURSOR PROTEIN SECRETASES, ASPARTIC ENDOPEPTIDASES, FRAGMENT- BASED DRUG DESIGN, FLUORESCENCE POLARISATION, DISULFIDE BOND, TRANSMEMBRANE, ZYMOGEN
3hw1:B (TYR342) to (PRO373) STRUCTURE OF BACE (BETA SECRETASE) IN COMPLEX WITH LIGAND EV2 | PROTEASE, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, AMYLOID PRECURSOR PROTEIN SECRETASES, ASPARTIC ENDOPEPTIDASES, FRAGMENT- BASED DRUG DESIGN, FLUORESCENCE POLARISATION, DISULFIDE BOND, TRANSMEMBRANE, ZYMOGEN
4kn7:H (ARG528) to (ASN582) X-RAY CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH BENZOXAZINORIFAMYCIN-2C | TRANSCRIPTION, DNA, RNA, TRANSFERASE-ANTIBIOTIC COMPLEX
1sgz:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF UNBOUND BETA-SECRETASE CATALYTIC DOMAIN. | BETA-SECRETASE, MEMAPSIN, BACE, ASPARTIC PROTEASE, PROTEASE FLAP, DRUG DESIGN, ASP2, ALZHEIMER'S DISEASE, HYDROLASE
1sgz:C (TYR342) to (PRO373) CRYSTAL STRUCTURE OF UNBOUND BETA-SECRETASE CATALYTIC DOMAIN. | BETA-SECRETASE, MEMAPSIN, BACE, ASPARTIC PROTEASE, PROTEASE FLAP, DRUG DESIGN, ASP2, ALZHEIMER'S DISEASE, HYDROLASE
1sgz:D (TYR342) to (PRO373) CRYSTAL STRUCTURE OF UNBOUND BETA-SECRETASE CATALYTIC DOMAIN. | BETA-SECRETASE, MEMAPSIN, BACE, ASPARTIC PROTEASE, PROTEASE FLAP, DRUG DESIGN, ASP2, ALZHEIMER'S DISEASE, HYDROLASE
1shw:A (LEU124) to (PRO148) EPHB2 / EPHRINA5 COMPLEX STRUCTURE | RECEPTOR TYROSINE KINASE, EPHRIN SIGNALING, HORMONE-GROWTH FACTOR- RECEPTOR COMPLEX
4kre:A (THR173) to (LEU190) STRUCTURE OF HUMAN ARGONAUTE-1 BOUND TO ENDOGENOUS SF9 RNA | EUKARYOTIC ARGONAUTE, GENE REGULATION, RNAI, SLICER, TRANSCRIPTION- RNA COMPLEX
3i25:C (TYR342) to (PRO373) POTENT BETA-SECRETASE 1 HYDROXYETHYLENE INHIBITOR | BACE, BETA-SECRETASE, INHIBITOR, ASPARTYL PROTEASE, PROTEASE, ALTERNATIVE SPLICING, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, POLYMORPHISM, TRANSMEMBRANE, ZYMOGEN
2w09:A (GLY330) to (SER348) CYP51 OF M. TUBERCULOSIS BOUND TO AN INHIBITOR CIS-4- METHYL-N-[(1S)-3-(METHYLSULFANYL)-1-(PYRIDIN-4- YLCARBAMOYL)PROPYL]CYCLOHEXANECARBOXAMIDE | STEROID BIOSYNTHESIS, PROTEIN-INHIBITOR COMPLEX, METAL-BINDING, OXIDOREDUCTASE, LIPID SYNTHESIS, NADP, IRON, HEME, CYTOPLASM, MONOOXYGENASE, X-RAY DIFFRACTION, STEROL BIOSYNTHESIS
2w3p:A (HIS22) to (LYS51) BOXC CRYSTAL STRUCTURE | COA, BOXC, LYASE, CROTONASE, RING CLEAVING, BURKHOLDERIA XENOVORANS LB400 CROTONASE
2w3p:B (HIS22) to (LYS51) BOXC CRYSTAL STRUCTURE | COA, BOXC, LYASE, CROTONASE, RING CLEAVING, BURKHOLDERIA XENOVORANS LB400 CROTONASE
1td0:A (SER32) to (SER80) VIRAL CAPSID PROTEIN SHP AT PH 5.5 | SHP, VIRAL PROTEIN
1td0:B (SER232) to (SER280) VIRAL CAPSID PROTEIN SHP AT PH 5.5 | SHP, VIRAL PROTEIN
1td0:C (SER432) to (SER480) VIRAL CAPSID PROTEIN SHP AT PH 5.5 | SHP, VIRAL PROTEIN
1td0:D (SER632) to (SER680) VIRAL CAPSID PROTEIN SHP AT PH 5.5 | SHP, VIRAL PROTEIN
3ivi:A (TYR403) to (PRO434) DESIGN AND SYNTHESIS OF POTENT BACE-1 INHIBITORS WITH CELLULAR ACTIVITY: STRUCTURE-ACTIVITY RELATIONSHIP OF P1 SUBSTITUENTS | ASPARTYL PROTEASE, BACE-1 INHIBITORS, ALZHEIMER'S DISEASE, STRUCTURE- BASED DRUG DESIGN, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3ivi:B (TYR403) to (PRO434) DESIGN AND SYNTHESIS OF POTENT BACE-1 INHIBITORS WITH CELLULAR ACTIVITY: STRUCTURE-ACTIVITY RELATIONSHIP OF P1 SUBSTITUENTS | ASPARTYL PROTEASE, BACE-1 INHIBITORS, ALZHEIMER'S DISEASE, STRUCTURE- BASED DRUG DESIGN, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3ivi:C (TYR403) to (PRO434) DESIGN AND SYNTHESIS OF POTENT BACE-1 INHIBITORS WITH CELLULAR ACTIVITY: STRUCTURE-ACTIVITY RELATIONSHIP OF P1 SUBSTITUENTS | ASPARTYL PROTEASE, BACE-1 INHIBITORS, ALZHEIMER'S DISEASE, STRUCTURE- BASED DRUG DESIGN, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
2wgf:C (VAL366) to (PHE404) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS C171Q KASA VARIANT | BETA KETOACYL SYNTHASE I, CYTOPLASM, TRANSFERASE, ACYLTRANSFERASE, LIPID SYNTHESIS, FATTY ACID BIOSYNTHESIS
4lm8:A (LEU374) to (PRO405) CRYSTAL STRUCTURE OF THE OUTER MEMBRANE DECAHEME CYTOCHROME MTRC | GREEK KEY, C TYPE CYTOCHROME ELECTRON TRANSPORT, OUTER MEMBRANE, ELECTRON TRANSPORT
1tww:B (ASP4) to (THR29) DIHYDROPTEROATE SYNTHETASE, WITH BOUND SUBSTRATE ANALOGUE PTPP, FROM BACILLUS ANTHRACIS | ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, TRANSFERASE
3vv8:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA SECETASE IN COMPLEX WITH 2-AMINO-3-METHYL-6- ((1S,2R)-2-(3'-METHYLBIPHENYL-4-YL)CYCLOPROPYL)PYRIMIDIN-4(3H)-ONE | ASPARTYL PROTEASE, BASE, BETA-SECRETASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2i07:B (VAL1528) to (SER1551) HUMAN COMPLEMENT COMPONENT C3B | C3B CONSISTS OF 12 DOMAINS, IMMUNE SYSTEM
3j1c:I (GLU355) to (GLY385) CRYO-EM STRUCTURE OF 9-FOLD SYMMETRIC RATCPN-ALPHA IN APO STATE | GROUP II CHAPERONIN, CHAPERONE
3j1c:J (GLU355) to (ARG384) CRYO-EM STRUCTURE OF 9-FOLD SYMMETRIC RATCPN-ALPHA IN APO STATE | GROUP II CHAPERONIN, CHAPERONE
1iry:A (GLN69) to (GLY93) SOLUTION STRUCTURE OF THE HMTH1, A NUCLEOTIDE POOL SANITIZATION ENZYME | NUDIX MOTIF(G37-L59), HYDROLASE
3wb5:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA SECETASE IN COMPLEX WITH (6S)-2-AMINO-3,6- DIMETHYL-6-[(1R,2R)-2-PHENYLCYCLOPROPYL]-3,4,5,6-TETRAHYDROPYRIMIDIN- 4-ONE | PROTEASE 2, ASP2, MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2, MEMAPSIN- 2, HYDROLASE
3wec:A (ASP310) to (LEU327) STRUCTURE OF P450 RAUA (CYP1050A1) COMPLEXED WITH A BIOSYNTHETIC INTERMEDIATE OF AURACHIN RE | P450 FOLD, MONOOXYGENASE (HYDROXYLASE), HEME, CYTOSOLIC ENZYME, OXIDOREDUCTASE
2iph:B (ALA2048) to (GLU2075) X-RAY STRUCTURE AT 1.75 A RESOLUTION OF A NOROVIRUS PROTEASE LINKED TO AN ACTIVE SITE DIRECTED PEPTIDE INHIBITOR | BETA BARREL, ALPHA HELIX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2iqg:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF HYDROXYETHYL SECONDARY AMINE-BASED PEPTIDOMIMETIC INHIBITOR OF HUMAN BETA-SECRETASE (BACE) | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
2j3k:B (MET1001) to (TYR1047) CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA DOUBLE BOND REDUCTASE (AT5G16970)-TERNARY COMPLEX II | OXIDOREDUCTASE, ARABIDOPSIS THALIANA, 4-HYDROXY-2- NONENAL, NADP, TERNARY COMPLEX II, DOUBLE BOND REDUCTASE (AT5G16970)
3wr3:B (ASP50) to (PRO80) CRYSTAL STRUCTURE OF THE ANAEROBIC DESB-GALLATE COMPLEX | TYPE II EXTRADIOL DIOXYGENASE, DOMAIN-SWAP DIMER, EXTRADIOL DIOXYGENASE, FE2+ BINDING, OXIDOREDUCTASE
4msk:C (SER1277) to (LYS1312) CO-CRYSTAL STRUCTURE OF TANKYRASE 1 WITH COMPOUND 34 | TANKYRASE, PARP, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4msk:D (SER1277) to (LYS1312) CO-CRYSTAL STRUCTURE OF TANKYRASE 1 WITH COMPOUND 34 | TANKYRASE, PARP, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mt9:B (SER1277) to (LYS1312) CO-CRYSTAL STRUCTURE OF TANKYRASE 1 WITH COMPOUND 49 | TANKYRASE, PARP, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1w51:A (TYR342) to (PRO373) BACE (BETA SECRETASE) IN COMPLEX WITH A NANOMOLAR NON- PEPTIDIC INHIBITOR | HYDROLASE/INHIBITOR, HYDROLASE/INHIBITOR COMPLEX, ALTERNATIVE SPLICING, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ASPARTYL PROTEASE, BASE, BETA-SECRETASE, GLYCOPROTEIN, HYDROLASE, MEMAPSIN 2, SIGNAL, TRANSMEMBRANE, ZYMOGEN
5bpk:B (GLY86) to (THR139) VARYING BINDING MODES OF INHIBITORS AND STRUCTURAL DIFFERENCES IN THE BINDING POCKETS OF DIFFERENT GAMMA-GLUTAMYLTRANSPEPTIDASES | GAMMA-GLUTAMYLTRANSPEPTIDASE, NTN-HYDROLASE, ACIVICIN, PROTEROS BIOSTRUCTURES GMBH, HYDROLASE
4n9i:B (GLY45) to (GLY71) CRYSTAL STRUCTURE OF TRANSCRIPTION REGULATION PROTEIN CRP COMPLEXED WITH CGMP | DNA BINDING, TRANSCRIPTION REGULATOR
4nbm:A (GLY301) to (VAL322) CRYSTAL STRUCTURE OF UVB PHOTORECEPTOR UVR8 AND LIGHT-INDUCED STRUCTURAL CHANGES AT 180K | 7-BLADE BETA-PROPELLER, GENE REGULATION
4nbm:B (GLY301) to (VAL322) CRYSTAL STRUCTURE OF UVB PHOTORECEPTOR UVR8 AND LIGHT-INDUCED STRUCTURAL CHANGES AT 180K | 7-BLADE BETA-PROPELLER, GENE REGULATION
4nbm:B (GLY353) to (ILE374) CRYSTAL STRUCTURE OF UVB PHOTORECEPTOR UVR8 AND LIGHT-INDUCED STRUCTURAL CHANGES AT 180K | 7-BLADE BETA-PROPELLER, GENE REGULATION
4nbm:C (GLY145) to (GLN167) CRYSTAL STRUCTURE OF UVB PHOTORECEPTOR UVR8 AND LIGHT-INDUCED STRUCTURAL CHANGES AT 180K | 7-BLADE BETA-PROPELLER, GENE REGULATION
2y05:C (SER2) to (LEU42) CRYSTAL STRUCTURE OF HUMAN LEUKOTRIENE B4 12-HYDROXYDEHYDROGENASE IN COMPLEX WITH NADP AND RALOXIFENE | OXIDOREDUCTASE
4nen:A (LYS917) to (PRO947) AN INTERNAL LIGAND-BOUND, METASTABLE STATE OF A LEUKOCYTE INTEGRIN, AXB2 | COMPLEMENT RECEPTOR, IC3B, FIBRINOGEN, DENATURATED PROTEINS, HEPARIN, ICAM, N-LINKED GLYCOSYLATION, MEMBRANE, CELL ADHESION
4nhv:B (ASP4) to (LEU26) CRYSTAL STRUCTURE OF B. ANTHRACIS DHPS WITH INTERFACIAL COMPOUND 4: 5- (TRIFLUOROMETHYL)-1,2-BENZOXAZOL-3-AMINE | TIM BARREL, TIM BAREL, TRANSFERASE, PTERIN, PABA, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3zlq:A (TYR354) to (SER383) BACE2 XAPERONE COMPLEX | HYDROLASE-IMMUNE SYSTEM COMPLEX
3zlq:B (TYR354) to (GLY384) BACE2 XAPERONE COMPLEX | HYDROLASE-IMMUNE SYSTEM COMPLEX
1kgy:G (GLU1519) to (ILE1538) CRYSTAL STRUCTURE OF THE EPHB2-EPHRINB2 COMPLEX | DEVELOPMENTAL PROTEIN, TRANSFERASE/TRANSFERASE RECEPTOR COMPLEX
1kgy:H (GLU1719) to (ILE1738) CRYSTAL STRUCTURE OF THE EPHB2-EPHRINB2 COMPLEX | DEVELOPMENTAL PROTEIN, TRANSFERASE/TRANSFERASE RECEPTOR COMPLEX
2y83:T (SER33) to (ASN78) ACTIN FILAMENT POINTED END | CONTRACTILE PROTEIN, CYTOSKELETON, CELL MOTILITY
1lec:A (ASN2) to (ILE31) STRUCTURES OF THE LECTIN IV OF GRIFFONIA SIMPLICIFOLIA AND ITS COMPLEX WITH THE LEWIS B HUMAN BLOOD GROUP DETERMINANT AT 2.0 ANGSTROMS RESOLUTION | LECTIN
1ln3:A (LEU117) to (GLN154) STRUCTURE OF HUMAN PHOSPHATIDYLCHOLINE TRANSFER PROTEIN IN COMPLEX WITH PALMITOYL-LINOLEOYL PHOSPHATIDYLCHOLINE (SELENO-MET PROTEIN) | START DOMAIN, LIPID BINDING PROTEIN
3k5g:B (TYR342) to (PRO373) HUMAN BACE-1 COMPLEX WITH BJC060 | ASPARTYL PROTEASE, ALZHEIMER'S DISEASE, STRUCTURE-BASED DESIGN, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, MEMBRANE, PROTEASE, TRANSMEMBRANE
4a5k:A (LEU497) to (VAL522) STRUCTURAL ANALYSES OF SLM1-PH DOMAIN DEMONSTRATE LIGAND BINDING IN THE NON-CANONICAL SITE | SIGNALING PROTEIN, NON-CANONICAL BINDING SITE, INOSITOL PHOSPHATE, PHOSPHOSERINE
4a5k:B (LEU497) to (VAL522) STRUCTURAL ANALYSES OF SLM1-PH DOMAIN DEMONSTRATE LIGAND BINDING IN THE NON-CANONICAL SITE | SIGNALING PROTEIN, NON-CANONICAL BINDING SITE, INOSITOL PHOSPHATE, PHOSPHOSERINE
4a5k:C (LEU497) to (VAL522) STRUCTURAL ANALYSES OF SLM1-PH DOMAIN DEMONSTRATE LIGAND BINDING IN THE NON-CANONICAL SITE | SIGNALING PROTEIN, NON-CANONICAL BINDING SITE, INOSITOL PHOSPHATE, PHOSPHOSERINE
4a5k:D (LEU497) to (VAL522) STRUCTURAL ANALYSES OF SLM1-PH DOMAIN DEMONSTRATE LIGAND BINDING IN THE NON-CANONICAL SITE | SIGNALING PROTEIN, NON-CANONICAL BINDING SITE, INOSITOL PHOSPHATE, PHOSPHOSERINE
3kci:A (GLY4116) to (VAL4137) THE THIRD RLD DOMAIN OF HERC2 | WD40, RCC1, STRUCTURAL GENOMICS CONSORTIUM, SGC, COILED COIL, LIGASE, METAL-BINDING, PHOSPHOPROTEIN, UBL CONJUGATION PATHWAY, WD REPEAT, ZINC, ZINC-FINGER
3kci:A (GLY4274) to (VAL4295) THE THIRD RLD DOMAIN OF HERC2 | WD40, RCC1, STRUCTURAL GENOMICS CONSORTIUM, SGC, COILED COIL, LIGASE, METAL-BINDING, PHOSPHOPROTEIN, UBL CONJUGATION PATHWAY, WD REPEAT, ZINC, ZINC-FINGER
1m4h:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SECRETASE COMPLEXED WITH INHIBITOR OM00-3 | MEMAPSIN2, BASE, ASP2, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1m4h:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SECRETASE COMPLEXED WITH INHIBITOR OM00-3 | MEMAPSIN2, BASE, ASP2, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2zji:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF THE HUMAN BACE1 CATALYTIC DOMAIN IN COMPLEX WITH N-[1-(2,6-DIMETHOXY-BENZYL)-PIPERIDIN-4-YL]-4-MERCAPTO-BUTYRAMIDE | BACE1, SMALL-MOLECULE INHIBITOR, ASPARTYL PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN
4oqs:A (GLU293) to (LEU312) CRYSTAL STRUCTURE OF CYP105AS1 | CYTOCHROME P450, MONOOXYGENASE, OXIDOREDUCTASE
4or4:A (GLN323) to (LYS341) STRUCTURE OF INFLUENZA B PB2 CAP-BINDING DOMAIN WITH Q325F MUTATION COMPLEX WITH M7GDP | CAP BINDING, VIRAL PROTEIN
4or4:B (GLN323) to (LYS341) STRUCTURE OF INFLUENZA B PB2 CAP-BINDING DOMAIN WITH Q325F MUTATION COMPLEX WITH M7GDP | CAP BINDING, VIRAL PROTEIN
4ads:I (PHE131) to (GLU160) CRYSTAL STRUCTURE OF PLASMODIAL PLP SYNTHASE COMPLEX | TRANSFERASE-TRANSFERASE COMPLEX, PYRIDOXAL 5-PHOSPHATE BIOSYNTHESIS
4ads:L (PHE131) to (GLU160) CRYSTAL STRUCTURE OF PLASMODIAL PLP SYNTHASE COMPLEX | TRANSFERASE-TRANSFERASE COMPLEX, PYRIDOXAL 5-PHOSPHATE BIOSYNTHESIS
1y8t:B (GLY232) to (GLY263) CRYSTAL STRUCTURE OF RV0983 FROM MYCOBACTERIUM TUBERCULOSIS- PROTEOLYTICALLY ACTIVE FORM | SERINE PROTEASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, UNKNOWN FUNCTION
3a4z:E (GLU293) to (LEU312) STRUCTURE OF CYTOCHROME P450 VDH MUTANT (VDH-K1) OBTAINED BY DIRECTED EVOLUTION | CYTOCHROME P450, VITAMIN D3 HYDROXYLASE, HEMOPROTEIN, MONOOXYGENASE, DIRECTED EVOLUTION, OXIDOREDUCTASE
4pj1:P (GLY3) to (ALA22) CRYSTAL STRUCTURE OF THE HUMAN MITOCHONDRIAL CHAPERONIN SYMMETRICAL 'FOOTBALL' COMPLEX | HUMAN, MITOCHONDRIAL, CHAPERONIN, COMPLEX, SYMMETRIC, CHAPERONE
4pj1:X (GLY3) to (ALA22) CRYSTAL STRUCTURE OF THE HUMAN MITOCHONDRIAL CHAPERONIN SYMMETRICAL 'FOOTBALL' COMPLEX | HUMAN, MITOCHONDRIAL, CHAPERONIN, COMPLEX, SYMMETRIC, CHAPERONE
4pj1:Y (GLY3) to (ALA22) CRYSTAL STRUCTURE OF THE HUMAN MITOCHONDRIAL CHAPERONIN SYMMETRICAL 'FOOTBALL' COMPLEX | HUMAN, MITOCHONDRIAL, CHAPERONIN, COMPLEX, SYMMETRIC, CHAPERONE
3l4c:B (GLN590) to (SER610) STRUCTURAL BASIS OF MEMBRANE-TARGETING BY DOCK180 | DOCK180, DOCK1, PHOSPHOINOSITIDE SPECIFICITY, GUANINE EXCHANGE FACTOR, RHO GTPASE, CYTOSKELETON, CELL MIGRATION, CELL POLARITY, APOPTOSIS, CYTOPLASM, GUANINE-NUCLEOTIDE RELEASING FACTOR, MEMBRANE, PHAGOCYTOSIS, PHOSPHOPROTEIN, SH3 DOMAIN, SH3-BINDING, CELL ADHESION, CELL INVASION
4pjt:D (SER947) to (PHE1009) STRUCTURE OF PARP1 CATALYTIC DOMAIN BOUND TO INHIBITOR BMN 673 | PARP1, INHIBITOR, COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3l59:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH710413 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3l59:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH710413 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3l5f:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH736201 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3l5f:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH736201 | BACE1, ALZHEIMERS, ALTERNATIVE SPLICING, ASPARTYL PROTEASE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENDOSOME, GLYCOPROTEIN, GOLGI APPARATUS, HYDROLASE, MEMBRANE, POLYMORPHISM, PROTEASE, TRANSMEMBRANE, ZYMOGEN
3ao0:A (MET141) to (THR166) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND (S)-2-AMINO-1-PROPANOL | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN, TIM BARREL
3ao0:C (MET141) to (THR166) CRYSTAL STRUCTURE OF ETHANOLAMINE AMMONIA-LYASE FROM ESCHERICHIA COLI COMPLEXED WITH CN-CBL AND (S)-2-AMINO-1-PROPANOL | (BETA/ALPHA)8 FOLD, COBALT, LYASE, COBALAMIN, TIM BARREL
3lpi:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH745132 | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE
3lpi:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH745132 | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE
5e0j:A (ALA48) to (GLU75) 1.20 A RESOLUTION STRUCTURE OF NOROVIRUS 3CL PROTEASE IN COMPLEX WITH A TRIAZOLE-BASED MACROCYCLIC (21-MER) INHIBITOR | PROTEASE, NOROVIRUS, NORWALK VIRUS, ANTIVIRAL INHIBITORS, TRIAZOLE MACROCYCLIC INHIBITOR, CELL PERMEABLE, PROTEASE-PROTEASE INHIBITOR COMPLEX
4ava:A (GLY63) to (GLY88) CRYSTAL STRUCTURE OF PROTEIN LYSINE ACETYLTRANSFERASE RV0998 FROM MYCOBACTERIUM TUBERCULOSIS | TRANSFERASE, ALLOSTERIC REGULATION, DOMAIN COUPLING
3azp:A (TRP298) to (LEU318) CRYSTAL STRUCTURE OF PUROMYCIN HYDROLASE S511A MUTANT | POP FAMILY, HYDROLASE
3azp:A (GLU390) to (PRO419) CRYSTAL STRUCTURE OF PUROMYCIN HYDROLASE S511A MUTANT | POP FAMILY, HYDROLASE
4b7s:A (GLU300) to (LEU319) PIKC D50N MUTANT BOUND TO THE 10-DML ANALOG WITH THE 3-(N,N- DIMETHYLAMINO)PROPANOATE ANCHORING GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS, INHIBITOR
4b7s:B (GLU300) to (LEU319) PIKC D50N MUTANT BOUND TO THE 10-DML ANALOG WITH THE 3-(N,N- DIMETHYLAMINO)PROPANOATE ANCHORING GROUP | OXIDOREDUCTASE, MONOOXYGENASE, PIKROMYCIN BIOSYNTHESIS, INHIBITOR
3mp1:A (GLU1109) to (ARG1136) COMPLEX STRUCTURE OF SGF29 AND TRIMETHYLATED H3K4 | HISTONE, TUDOR DOMAIN, H3K4ME3, SAGA, HISTONE BINDING PROTEIN
4bss:E (CYS38) to (PHE67) STRUCTURE OF THE ECTODOMAIN OF LGR5 IN COMPLEX WITH R-SPONDIN-1 (FU1FU2) IN P21 CRYSTAL FORM | SIGNALING PROTEIN, ADULT STEM CELL, LEUCINE-RICH REPEAT G-PROTEIN COUPLED RECEPTOR, LEUCINE-RICH REPEAT, FURIN DOMAIN, WNT SIGNALING, CONGENITAL ANONYCHIA
4bt4:A (GLY192) to (ASP214) ACETOLACTATE DECARBOXYLASE WITH A BOUND (2S,3S)-2,3- DIHYDROXY-2-METHYLBUTANOIC ACID | LYASE, ACETOIN BIOSYNTHESIS, STEREOSELECTIVE DECARBOXYLATION, BIFUNCTIONAL ENZYME
4buf:A (SER1124) to (ARG1159) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 2-(4- ACETYLPHENYL)-3,4-DIHYDROQUINAZOLIN-4-ONE | TRANSFERASE, PROTEIN-LIGAND COMPLEX, DIPHTHERIA TOXIN LIKE FOLD, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3n4l:A (TYR348) to (PRO379) BACE-1 IN COMPLEX WITH ELN380842 | BACE, HYDROXYETHYLAMINE, BETA SECRETASE, ALZHEIMER'S DISEASE, AD, BETA-AMYLOID PRECURSOR PROTEIN, BETA-APP, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3n4l:B (TYR348) to (PRO379) BACE-1 IN COMPLEX WITH ELN380842 | BACE, HYDROXYETHYLAMINE, BETA SECRETASE, ALZHEIMER'S DISEASE, AD, BETA-AMYLOID PRECURSOR PROTEIN, BETA-APP, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3c2w:B (ALA28) to (PRO55) CRYSTAL STRUCTURE OF THE PHOTOSENSORY CORE DOMAIN OF P. AERUGINOSA BACTERIOPHYTOCHROME PABPHP IN THE PFR STATE | KNOT STRUCTURE, CHROMOPHORE, KINASE, PHOSPHOPROTEIN, PHOTORECEPTOR PROTEIN, RECEPTOR, SENSORY TRANSDUCTION, TRANSFERASE, SIGNALING PROTEIN
3c2w:D (ALA28) to (PRO55) CRYSTAL STRUCTURE OF THE PHOTOSENSORY CORE DOMAIN OF P. AERUGINOSA BACTERIOPHYTOCHROME PABPHP IN THE PFR STATE | KNOT STRUCTURE, CHROMOPHORE, KINASE, PHOSPHOPROTEIN, PHOTORECEPTOR PROTEIN, RECEPTOR, SENSORY TRANSDUCTION, TRANSFERASE, SIGNALING PROTEIN
4ra0:A (CYS283) to (LEU314) AN ENGINEERED AXL 'DECOY RECEPTOR' EFFECTIVELY SILENCES THE GAS6-AXL SIGNALING AXIS | AXL, GAS6, CANCER, METASTASIS, SIGNALING PROTEIN
4rcd:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH A 2-AMINOOXAZOLINE 4- AZAXANTHENE INHIBITOR | ASPARTYL PROTEASE, ALZHEIMER'S DISEASE, APP, AMYLOID PRECURSOR PROTEIN, BRAIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3cic:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH709583 | BACE1, ASPARTYL PROTEASE, HYDROLASE
3cic:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO SCH709583 | BACE1, ASPARTYL PROTEASE, HYDROLASE
4rga:A (ALA199) to (THR221) PHAGE 1358 RECEPTOR BINDING PROTEIN IN COMPLEX WITH THE TRISACCHARIDE GLCNAC-GALF-GLCOME | ALPHA/BETA PROTEIN, PHAGE RECEPTOR BINDING PROTEIN, LACTOCOCCUS LACTIS SMQ388, VIRAL PROTEIN
3nim:B (GLU131) to (CYS175) THE STRUCTURE OF UBR BOX (RRAA) | E3 UBIQUITIN LIGASE, UBR BOX, ZINC-BINDING PROTEIN, N-END RULE, LIGASE, METAL BINDING PROTEIN
3ckp:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH INHIBITOR | BETA-SECRETASE, ASPARTYL PROTEASE, ALTERNATIVE SPLICING, GLYCOPROTEIN, HYDROLASE, MEMBRANE, TRANSMEMBRANE, ZYMOGEN
4rj3:A (GLY11) to (ALA31) CDK2 WITH EGFR INHIBITOR COMPOUND 8 | PROTEIN KINASE, PHOSPHOTRANSFER CATALYST, LYSINE ACETYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3nsh:A (TYR348) to (PRO379) BACE-1 IN COMPLEX WITH ELN475957 | MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2, MEMAPSIN-2, ASPARTYL PROTEASE 2, ASP 2, ASP2, BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1, BETA-SITE APP CLEAVING ENZYME 1, HYDROLASE
3nsh:B (TYR348) to (PRO379) BACE-1 IN COMPLEX WITH ELN475957 | MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2, MEMAPSIN-2, ASPARTYL PROTEASE 2, ASP 2, ASP2, BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1, BETA-SITE APP CLEAVING ENZYME 1, HYDROLASE
3nsh:C (TYR348) to (PRO379) BACE-1 IN COMPLEX WITH ELN475957 | MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2, MEMAPSIN-2, ASPARTYL PROTEASE 2, ASP 2, ASP2, BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1, BETA-SITE APP CLEAVING ENZYME 1, HYDROLASE
3ocp:B (LYS162) to (GLY182) CRYSTAL STRUCTURE OF CAMP BOUND CGMP-DEPENDENT PROTEIN KINASE(92-227) | SERINE/THREONINE KINASE, TF2I AND IRAG, TRANSFERASE
4try:C (TYR403) to (PRO434) STRUCTURE OF BACE1 COMPLEX WITH A HEA-TYPE INHIBITOR | HYDRASE PROTEINASE CONVERTING, DESIGNED INHIBITOR, HYDRASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ohf:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH BMS-655295 AKA N~3~-((1S,2R)-1- BENZYL-2-HYDROXY-3-((3- METHOXYBENZYL)AMINO)PROPYL)-N~1~, N~1~-DIBUTYL-1H-INDOLE-1,3- DICARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2,ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4d5b:B (ASN55) to (ASP88) CRYSTAL STRUCTURE OF CYMA FROM KLEBSIELLA OXYTOCA | TRANSPORT PROTEIN, OUTER MEMBRANE CHANNEL, CYCLODEXTRIN TRANSPORT, BETA BARREL
4d83:C (TYR331) to (PRO362) CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE IN COMPLEX WITH NVP-BUR436, DERIVED FROM A CO-CRYSTALLIZATION EXPERIMENT | BETA-SECRETASE, MEMAPSIN2, BACE1, ASPARTIC PROTEINASE, ALZHEIMER'S DISEASE, ENZYME INHIBITOR COMPLEX, STRUCTURE-BASED DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4d9s:B (GLY145) to (GLN167) CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA UVR8 (UV RESISTANCE LOCUS 8) | UV RESISTANCE, UV-B PHOTORECEPTOR, TRYPTOPHAN CHROMOPHORES, HOMODIMER, COP1, CHROMATIN-BINDING PROTEIN
4daf:B (ASP4) to (ILE25) CRYSTAL STRUCTURE OF B. ANTHRACIS DHPS WITH COMPOUND 19 | TIM BARREL, DHPS INHIBITOR, TRANSFERASE, PABA, DHPP, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
5hh0:A (HIS159) to (PRO187) CRYSTAL STRUCTURE OF HUMAN NAA60 IN COMPLEX WITH COA | N-TERMINAL ACETYLATION, NATS, PROTEIN MODIFICATION, TRANSFERASE
4djx:A (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 5-(3-(5-CHLOROPYRIDIN-3-YL)PHENYL)-5- CYCLOPROPYL-2-IMINO-3-METHYLIMIDAZOLIDIN-4-ONE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4djx:B (TYR403) to (PRO434) STRUCTURE OF BACE BOUND TO 5-(3-(5-CHLOROPYRIDIN-3-YL)PHENYL)-5- CYCLOPROPYL-2-IMINO-3-METHYLIMIDAZOLIDIN-4-ONE | BACE1, ALZHEIMERS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5htz:A (TYR403) to (PRO434) BACE1 IN COMPLEX WITH (S)-5-(3-CHLORO-5-(5-(PROP-1-YN-1-YL)PYRIDIN-3- YL)THIOPHEN-2-YL)-2,5-DIMETHYL-1,2,4-THIADIAZINAN-3-IMINIUM 1,1- DIOXIDE | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5htz:B (TYR403) to (PRO434) BACE1 IN COMPLEX WITH (S)-5-(3-CHLORO-5-(5-(PROP-1-YN-1-YL)PYRIDIN-3- YL)THIOPHEN-2-YL)-2,5-DIMETHYL-1,2,4-THIADIAZINAN-3-IMINIUM 1,1- DIOXIDE | ALZHEIMER'S, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4exg:A (TYR390) to (PRO421) DESIGN AND SYNTHESIS OF POTENT HYDROXYETHYLAMINE (HEA) BACE-1 INHIBITORS | BACE, BETA-SECRETASE, STATINE, INHIBITOR, ASPARTYL PROTEASE, GLYCOPROTEIN, MEMBRANE, PROTEASE, TRANSMEMBRANE, ZYMOGEN, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3qpz:A (MET1) to (GLY20) CRYSTAL STRUCTURE OF THE N59A MUTANT OF THE 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8P, KDOPS, KDO8PS, TIM BARREL, TRANSFERASE
3qpz:B (MET1) to (GLY20) CRYSTAL STRUCTURE OF THE N59A MUTANT OF THE 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8P, KDOPS, KDO8PS, TIM BARREL, TRANSFERASE
3qpz:C (MET1) to (GLY20) CRYSTAL STRUCTURE OF THE N59A MUTANT OF THE 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8P, KDOPS, KDO8PS, TIM BARREL, TRANSFERASE
3qpz:D (MET1) to (GLY20) CRYSTAL STRUCTURE OF THE N59A MUTANT OF THE 3-DEOXY-D-MANNO- OCTULOSONATE 8-PHOSPHATE SYNTHASE (KDO8PS) FROM NEISSERIA MENINGITIDIS | MANNO-OCTULOSONATE, SYNTHASE, LIPOPOLYSACCHARIDE, KDOP, KDO8P, KDOPS, KDO8PS, TIM BARREL, TRANSFERASE
3r2f:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH BMS-693391 AKA (2S)-2-((3R)-3-ACETAMIDO-3-ISOBUTYL-2-OXO-1- PYRROLIDINYL)-N-((1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-2-((2R,4R)- 4-PROPOXY-2-PYRROLIDINYL)ETHYL)-4-PHENYLBUTANAMIDE | ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, BETA-SECRETASE, MEMAPSIN 2, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3r2f:B (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH BMS-693391 AKA (2S)-2-((3R)-3-ACETAMIDO-3-ISOBUTYL-2-OXO-1- PYRROLIDINYL)-N-((1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-2-((2R,4R)- 4-PROPOXY-2-PYRROLIDINYL)ETHYL)-4-PHENYLBUTANAMIDE | ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, BETA-SECRETASE, MEMAPSIN 2, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3r2f:D (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH BMS-693391 AKA (2S)-2-((3R)-3-ACETAMIDO-3-ISOBUTYL-2-OXO-1- PYRROLIDINYL)-N-((1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-2-((2R,4R)- 4-PROPOXY-2-PYRROLIDINYL)ETHYL)-4-PHENYLBUTANAMIDE | ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, BETA-SECRETASE, MEMAPSIN 2, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3r2f:E (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH BMS-693391 AKA (2S)-2-((3R)-3-ACETAMIDO-3-ISOBUTYL-2-OXO-1- PYRROLIDINYL)-N-((1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-2-((2R,4R)- 4-PROPOXY-2-PYRROLIDINYL)ETHYL)-4-PHENYLBUTANAMIDE | ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, BETA-SECRETASE, MEMAPSIN 2, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4fma:K (ASN277) to (MET312) ESPG STRUCTURE | ALPHA AND BETA FOLD, RAB1 GAP, RAB1 GTPASE, PROTEIN BINDING
3rbh:A (THR247) to (ASP306) STRUCTURE OF ALGINATE EXPORT PROTEIN ALGE FROM PSEUDOMONAS AERUGINOSA | BETA-BARREL, ALGINATE EXPORT, MEMBRANE PROTEIN, TRANSPORT PROTEIN
3rdi:B (GLY45) to (GLY71) DOMAIN-DOMAIN FLEXIBILITY LEADS TO ALLOSTERY WITHIN THE CAMP RECEPTOR PROTEIN (CRP) | CAMP RECEPTOR PROTEIN (CRP), ALLOSTERY, DNA BINDING CYCLIC AMP, TRANSCRIPTION REGULATOR, CATABOLITE ACTIVATOR PROTEIN (CAP), DNA BINDING PROTEIN
4fri:A (TYR342) to (PRO373) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH BIARYLSPIRO AMINOOXAZOLINE 6 | MEMBRANE PROTEIN, ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, HYDROLASE- INHIBITOR COMPLEX
4fse:A (TYR390) to (PRO421) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH N-(N-(4-AMINO-3,5- DICHLOROBENZYL)CARBAMIMIDOYL)-3-(4- METHOXYPHENYL)-5- METHYL-4-ISOTHIAZOLECARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2, BASE, ASPARTIC PROTEASE, HYDROLASE-INHIBITOR COMPLEX
4fse:B (TYR390) to (PRO421) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH N-(N-(4-AMINO-3,5- DICHLOROBENZYL)CARBAMIMIDOYL)-3-(4- METHOXYPHENYL)-5- METHYL-4-ISOTHIAZOLECARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2, BASE, ASPARTIC PROTEASE, HYDROLASE-INHIBITOR COMPLEX
4fse:D (TYR390) to (PRO421) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH N-(N-(4-AMINO-3,5- DICHLOROBENZYL)CARBAMIMIDOYL)-3-(4- METHOXYPHENYL)-5- METHYL-4-ISOTHIAZOLECARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2, BASE, ASPARTIC PROTEASE, HYDROLASE-INHIBITOR COMPLEX
4fse:E (TYR390) to (PRO421) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH N-(N-(4-AMINO-3,5- DICHLOROBENZYL)CARBAMIMIDOYL)-3-(4- METHOXYPHENYL)-5- METHYL-4-ISOTHIAZOLECARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2, BASE, ASPARTIC PROTEASE, HYDROLASE-INHIBITOR COMPLEX
5jyx:B (LEU10) to (ALA44) CRYSTAL STRUCTURE OF THE COVALENT THIOIMIDE INTERMEDIATE OF THE ARCHAEOSINE SYNTHASE QUEF-LIKE | THIOIMIDE, AMIDINOTRANSFERASE, C2 SPACE GROUP, HYDROLASE, TRANSFERASE
5jyx:C (LEU10) to (ALA44) CRYSTAL STRUCTURE OF THE COVALENT THIOIMIDE INTERMEDIATE OF THE ARCHAEOSINE SYNTHASE QUEF-LIKE | THIOIMIDE, AMIDINOTRANSFERASE, C2 SPACE GROUP, HYDROLASE, TRANSFERASE
5jyx:E (LEU10) to (ALA44) CRYSTAL STRUCTURE OF THE COVALENT THIOIMIDE INTERMEDIATE OF THE ARCHAEOSINE SYNTHASE QUEF-LIKE | THIOIMIDE, AMIDINOTRANSFERASE, C2 SPACE GROUP, HYDROLASE, TRANSFERASE
5jyx:F (LEU10) to (ILE45) CRYSTAL STRUCTURE OF THE COVALENT THIOIMIDE INTERMEDIATE OF THE ARCHAEOSINE SYNTHASE QUEF-LIKE | THIOIMIDE, AMIDINOTRANSFERASE, C2 SPACE GROUP, HYDROLASE, TRANSFERASE
5jyx:H (LEU10) to (ALA44) CRYSTAL STRUCTURE OF THE COVALENT THIOIMIDE INTERMEDIATE OF THE ARCHAEOSINE SYNTHASE QUEF-LIKE | THIOIMIDE, AMIDINOTRANSFERASE, C2 SPACE GROUP, HYDROLASE, TRANSFERASE
5jyx:I (LEU10) to (ALA44) CRYSTAL STRUCTURE OF THE COVALENT THIOIMIDE INTERMEDIATE OF THE ARCHAEOSINE SYNTHASE QUEF-LIKE | THIOIMIDE, AMIDINOTRANSFERASE, C2 SPACE GROUP, HYDROLASE, TRANSFERASE
5jyx:J (LEU10) to (ALA44) CRYSTAL STRUCTURE OF THE COVALENT THIOIMIDE INTERMEDIATE OF THE ARCHAEOSINE SYNTHASE QUEF-LIKE | THIOIMIDE, AMIDINOTRANSFERASE, C2 SPACE GROUP, HYDROLASE, TRANSFERASE
5jyx:K (LEU10) to (ALA44) CRYSTAL STRUCTURE OF THE COVALENT THIOIMIDE INTERMEDIATE OF THE ARCHAEOSINE SYNTHASE QUEF-LIKE | THIOIMIDE, AMIDINOTRANSFERASE, C2 SPACE GROUP, HYDROLASE, TRANSFERASE
5jyx:N (LEU10) to (ALA44) CRYSTAL STRUCTURE OF THE COVALENT THIOIMIDE INTERMEDIATE OF THE ARCHAEOSINE SYNTHASE QUEF-LIKE | THIOIMIDE, AMIDINOTRANSFERASE, C2 SPACE GROUP, HYDROLASE, TRANSFERASE
5jyx:O (LEU10) to (ALA44) CRYSTAL STRUCTURE OF THE COVALENT THIOIMIDE INTERMEDIATE OF THE ARCHAEOSINE SYNTHASE QUEF-LIKE | THIOIMIDE, AMIDINOTRANSFERASE, C2 SPACE GROUP, HYDROLASE, TRANSFERASE
4gqc:C (ASP13) to (PRO42) CRYSTAL STRUCTURE OF AEROPYRUM PERNIX PEROXIREDOXIN Q ENZYME IN FULLY- FOLDED AND LOCALLY-UNFOLDED CONFORMATIONS | CXXXXC MOTIF, FULLY FOLDED, LOCALLY UNFOLDED, PEROXIDE, DTT, STRUCTURAL GENOMICS, RIKEN, PEROXIREDOXIN, REDUCES PEROXIDES, DISULFIDE, OXIDOREDUCTASE
4gqc:D (PHE14) to (PRO42) CRYSTAL STRUCTURE OF AEROPYRUM PERNIX PEROXIREDOXIN Q ENZYME IN FULLY- FOLDED AND LOCALLY-UNFOLDED CONFORMATIONS | CXXXXC MOTIF, FULLY FOLDED, LOCALLY UNFOLDED, PEROXIDE, DTT, STRUCTURAL GENOMICS, RIKEN, PEROXIREDOXIN, REDUCES PEROXIDES, DISULFIDE, OXIDOREDUCTASE
4gqs:A (CYS372) to (SER390) STRUCTURE OF HUMAN MICROSOMAL CYTOCHROME P450 (CYP) 2C19 | MONOOXYGENASE, DRUG METABOLIZING ENZYME, OXIDOREDUCTASE, HEME PROTEIN
4gqs:B (CYS372) to (SER390) STRUCTURE OF HUMAN MICROSOMAL CYTOCHROME P450 (CYP) 2C19 | MONOOXYGENASE, DRUG METABOLIZING ENZYME, OXIDOREDUCTASE, HEME PROTEIN
5kqf:A (TYR390) to (PRO421) (4~{S},6~{S})-4-[2,4-BIS(FLUORANYL)PHENYL]-4-METHYL-6-PYRIMIDIN-5-YL- 5,6-DIHYDRO-1,3-THIAZIN-2-AMINE (COMPOUND 12) BOUND TO BACE1 | BACE-1, SMALL MOLECULE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5kr8:A (TYR390) to (PRO421) (4~{S},6~{S})-4-[2,4-BIS(FLUORANYL)PHENYL]-6-(3,5-DIMETHYL-1,2-OXAZOL- 4-YL)-4-METHYL-5,6-DIHYDRO-1,3-THIAZIN-2-AMINE (COMPOUND 5) BOUND TO BACE1 | BACE-1, SMALL MOLECULE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5l1e:C (GLN335) to (LEU363) AMPA SUBTYPE IONOTROPIC GLUTAMATE RECEPTOR GLUA2 IN COMPLEX WITH NONCOMPETITIVE INHIBITOR CP465022 | TRANSPORTER, MEMBRANE PROTEIN, TRANSPORT PROTEIN, TRANSPORT PROTEIN- INHIBITOR COMPLEX