2aid:A (VAL11) to (GLU34) STRUCTURE OF A NON-PEPTIDE INHIBITOR COMPLEXED WITH HIV-1 PROTEASE: DEVELOPING A CYCLE OF STRUCTURE-BASED DRUG DESIGN | ASPARTYL PROTEASE, HIV, NON-PEPTIDE INHIBITOR, DRUG DESIGN
1a30:B (VAL11) to (GLU34) HIV-1 PROTEASE COMPLEXED WITH A TRIPEPTIDE INHIBITOR | ASPARTIC PROTEASE, HIV PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1a8k:B (ARG8) to (GLU34) CRYSTALLOGRAPHIC ANALYSIS OF HUMAN IMMUNODEFICIENCY VIRUS 1 PROTEASE WITH AN ANALOG OF THE CONSERVED CA-P2 SUBSTRATE: INTERACTIONS WITH FREQUENTLY OCCURRING GLUTAMIC ACID RESIDUE AT P2' POSITION OF SUBSTRATES | HUMAN IMMUNODEFICIENCY VIRUS PROTEASE, PROTON-MEDIATED INTERACTION, VIRAL MATURATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1a94:B (ARG8) to (GLU34) STRUCTURAL BASIS FOR SPECIFICITY OF RETROVIRAL PROTEASES | HUMAN IMMUNODEFICIENCY VIRUS PROTEASE, ROUS SARCOMA VIRUS PROTEASE, PROTEIN-MEDIATED INTERACTION, VIRAL MATURATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2anu:D (ILE171) to (SER192) CRYSTAL STRUCTURE OF PREDICTED METAL-DEPENDENT PHOSPHOESTERASE (PHP FAMILY) (TM0559) FROM THERMOTOGA MARITIMA AT 2.40 A RESOLUTION | TM0559, PREDICTED METAL-DEPENDENT PHOSPHOESTERASE (PHP FAMILY), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI, METAL BINDING PROTEIN
2aoi:B (VAL111) to (GLU134) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE WITH A SUBSTRATE ANALOG P1-P6 | HIV-1 PROTEASE, MUTANT, DIMER, SUBSTRATE ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2aoj:B (VAL111) to (GLU134) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE WITH A SUBSTRATE ANALOG P6-PR | HIV-1 PROTEASE, MUTANT, DIMER, SUBSTRATE ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ebz:B (VAL111) to (GLY135) HIGH RESOLUTION HIV-2 PROTEASE STRUCTURE IN COMPLEX WITH CLINICAL DRUG DARUNAVIR | HIV-2, ASPARTIC PROTEASE, INHIBITOR,PROTEASE-DRUG COMPLEX, HYDROLASE
3ec0:B (VAL111) to (GLY135) HIGH RESOLUTION HIV-2 PROTEASE STRUCTURE IN COMPLEX WITH ANTIVIRAL INHIBITOR GRL-06579A | HIV-2, ASPARTIC PROTEASE, INHIBITOR, PROTEASE-INHIBITOR COMPLEX, HYDROLASE
2aqu:A (PRO9) to (GLU34) STRUCTURE OF HIV-1 PROTEASE BOUND TO ATAZANAVIR | AIDS, ASPARTYL PROTEASE, HYDROLASE,, HYDROLASE
2aqu:B (PRO9) to (GLU34) STRUCTURE OF HIV-1 PROTEASE BOUND TO ATAZANAVIR | AIDS, ASPARTYL PROTEASE, HYDROLASE,, HYDROLASE
1aaq:A (PRO9) to (GLU34) HYDROXYETHYLENE ISOSTERE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE: STRUCTURE-ACTIVITY ANALYSIS USING ENZYME KINETICS, X-RAY CRYSTALLOGRAPHY, AND INFECTED T-CELL ASSAYS | ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4gye:B (PRO9) to (GLU34) MDR 769 HIV-1 PROTEASE IN COMPLEX WITH REDUCED P1F | MULTI-DRUG RESISTANCE, PROTEASE INHIBITOR, DRUG RESISTANCE, SUBSTRATE PEPTIDE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2ok7:A (HIS52) to (GLU124) FERREDOXIN-NADP+ REDUCTASE FROM PLASMODIUM FALCIPARUM WITH 2'P-AMP | DISULFIDE-STABILIZED DIMER, OXIDOREDUCTASE
1acx:A (ALA3) to (GLN33) ACTINOXANTHIN STRUCTURE AT THE ATOMIC LEVEL (RUSSIAN) | ANTIBACTERIAL PROTEIN
2okx:B (TRP10) to (ASP47) CRYSTAL STRUCTURE OF GH78 FAMILY RHAMNOSIDASE OF BACILLUS SP. GL1 AT 1.9 A | ALPHA BARREL, RHAMNOSIDASE, GLYCOSIDE HYDROLASE FAMILY 78, INVERTASE, HYDROLASE
2auk:E (THR106) to (ALA138) STRUCTURE OF E. COLI RNA POLYMERASE BETA' G/G' INSERT | SANDWICH-BARREL HYBRID MOTIF, TRANSFERASE
3ef4:B (ALA1) to (ASP38) CRYSTAL STRUCTURE OF NATIVE PSEUDOAZURIN FROM HYPHOMICROBIUM DENITRIFICANS | COPPER, ELECTRON TRANSFER, BLUE COPPER PROTEIN, ELECTRON TRANSPORT
2avv:B (THR12) to (GLU34) KINETICS, STABILITY, AND STRUCTURAL CHANGES IN HIGH RESOLUTION CRYSTAL STRUCTURES OF HIV-1 PROTEASE WITH DRUG RESISTANT MUTATIONS L24I, I50V, AND G73S | DRUG RESISTANCE, HIV-1 PROTEASE,INDINAVIR, SUBSTRATE ANALOG, NON-ACTIVE SITE MUTANTS., HYDROLASE
4gzf:A (PRO9) to (GLU34) MULTI-DRUG RESISTANT HIV-1 PROTEASE 769 VARIANT WITH REDUCED LRF PEPTIDE | MULTI-DRUG RESISTANCE, PROTEASE INHIBITOR, DRUG RESISTANCE, SUBSTRATE PEPTIDES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ahs:B (ARG147) to (GLY168) CRYSTAL STRUCTURE OF THE TOP DOMAIN OF AFRICAN HORSE SICKNESS VIRUS VP7 | CORE PROTEIN, GLYCOPROTEIN, COAT PROTEIN (VIRAL), VIRAL PROTEIN
2onl:A (THR7) to (PRO29) CRYSTAL STRUCTURE OF THE P38A-MAPKAP KINASE 2 HETERODIMER | HETERODIMER, KINASE, NLS, NES, DOCKING GROOVE, TRANSFERASE
2onl:B (THR7) to (PRO29) CRYSTAL STRUCTURE OF THE P38A-MAPKAP KINASE 2 HETERODIMER | HETERODIMER, KINASE, NLS, NES, DOCKING GROOVE, TRANSFERASE
4wm8:B (VAL13) to (ALA34) CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS D68 | ENTEROVIRUS, CAPSID, BETA JELLY ROLL, VIRUS
2az9:A (THR12) to (GLU34) HIV-1 PROTEASE NL4-3 1X MUTANT | HIV, PROTEASE, INHIBITOR, TL-3, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ehk:A (ALA189) to (LEU224) CRYSTAL STRUCTURE OF PRU DU AMANDIN, AN ALLERGENIC PROTEIN FROM PRUNUS DULCIS | GLOBULIN, 11S SEED STORAGE PROTEIN, PLANT PROTEIN
1ajv:B (VAL11) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH THE CYCLIC SULFAMIDE INHIBITOR AHA006 | PROTEASE, ASPARTYL PROTEASE, NON-PEPTIDE INHIBITOR, DRUG DESIGN, HIV-1
1ajx:B (VAL11) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH THE CYCLIC UREA INHIBITOR AHA001 | PROTEASE, ASPARTYL PROTEASE, NON-PEPTIDE INHIBITOR, DRUG DESIGN, HIV-1
2oot:A (SER129) to (GLY172) A HIGH RESOLUTION STRUCTURE OF LIGAND-FREE HUMAN GLUTAMATE CARBOXYPEPTIDASE II | METALLOPEPTIDASE, FOLATE HYDROLASE, PROSTATE-SPECIFIC MEMBRANE ANTIGEN, NAALADASE, GCPII, HYDROLASE
4h12:A (ILE1602) to (LYS1639) THE CRYSTAL STRUCTURE OF METHYLTRANSFERASE DOMAIN OF HUMAN SET DOMAIN- CONTAINING PROTEIN 2 IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE | METHYLTRANSFERASE, SET DOMAIN-CONTAINING PROTEIN 2, S-ADENOSYL-L- HOMOCYSTEINE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, ACTIVATOR, CHROMATIN REGULATOR, DNA-BINDING, METHYLATION, NUCLEUS, PHOSPHOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE
3rwt:G (PHE1) to (ARG49) CRYSTAL STRUCTURE OF CIRCULAR PERMUTATED RED FLUORESCENT PROTEIN MKATE(CP 154-153) | GFP-LIKE FLUORESCENT PROTEIN, MKATE, CIRCULAR PERMUTATED, RED FLUORESCENTPROTEIN, FLUORESCENT PROTEIN
1anu:A (VAL1) to (ASP40) COHESIN-2 DOMAIN OF THE CELLULOSOME FROM CLOSTRIDIUM THERMOCELLUM | COHESIN, SCAFFOLDING, CELLULOSE DIGESTION, BETA SANDWICH, THERMOPHILE
1npa:A (ARG8) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE-HUP | PROTEASE, HIV, ASPARTYL PROTEASE, HYDROLASE
1npa:B (PRO9) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE-HUP | PROTEASE, HIV, ASPARTYL PROTEASE, HYDROLASE
1npv:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH LDC271 | PROTEASE, HYDROLASE
1npv:B (PRO209) to (GLU234) CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH LDC271 | PROTEASE, HYDROLASE
1npw:A (ARG8) to (GLU34) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH LGZ479 | PROTEASE, HYDROLASE
1npw:B (PRO209) to (GLU234) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH LGZ479 | PROTEASE, HYDROLASE
4h45:A (CYS92) to (PHE117) PRODUCT COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE WITH MUTATION E192Q | ALLOSTERIC ENZYMES, COOPERATIVITY, OLIGOMERIZATION, HYDROLASE
3ekp:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF THE INHIBITOR AMPRENAVIR (APV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10I/G48V/I54V/V64I/V82A)REFER: FLAP+ IN CITATION | HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, AMPRENAVIR, AIDS, HYDROLASE
3ekp:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF THE INHIBITOR AMPRENAVIR (APV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10I/G48V/I54V/V64I/V82A)REFER: FLAP+ IN CITATION | HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, AMPRENAVIR, AIDS, HYDROLASE
3ekp:C (VAL11) to (GLU34) CRYSTAL STRUCTURE OF THE INHIBITOR AMPRENAVIR (APV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10I/G48V/I54V/V64I/V82A)REFER: FLAP+ IN CITATION | HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, AMPRENAVIR, AIDS, HYDROLASE
3ekq:B (PRO9) to (GLU34) CRYSTAL STRUCTURE OF INHIBITOR SAQUINAVIR (SQV) IN COMPLEX WITH MULTI- DRUG RESISTANT HIV-1 PROTEASE (L63P/V82T/I84V) (REFERRED TO AS ACT IN PAPER) | PROTEASE INHIBITOR, DRUG RESISTANCE, ENTROPY ENTHALPY COMPENSATION, AIDS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASE
3ekt:C (VAL11) to (GLU34) CRYSTAL STRUCTURE OF THE INHIBITOR DARUNAVIR (DRV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10F/G48V/I54V/V64I/V82A) (REFER: FLAP+ IN CITATION.) | HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, DARUNAVIR, AIDS, HYDROLASE
3ekt:D (VAL11) to (GLU34) CRYSTAL STRUCTURE OF THE INHIBITOR DARUNAVIR (DRV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10F/G48V/I54V/V64I/V82A) (REFER: FLAP+ IN CITATION.) | HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, DARUNAVIR, AIDS, HYDROLASE
3ekv:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF THE WILD TYPE HIV-1 PROTEASE WITH THE INHIBITOR, AMPRENAVIR | PROTEASE INHIBITOR, DRUG RESISTANCE, AMPRENAVIR, HIV PROTEASE, AIDS, PROTEASE, HYDROLASE
3ekv:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF THE WILD TYPE HIV-1 PROTEASE WITH THE INHIBITOR, AMPRENAVIR | PROTEASE INHIBITOR, DRUG RESISTANCE, AMPRENAVIR, HIV PROTEASE, AIDS, PROTEASE, HYDROLASE
3eky:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV PROTEASE IN COMPLEX WITH THE INHIBITOR, ATAZANAVIR | HIV PROTEASE, PROTEASE INHIBITORS, DRUG RESISTANCE, ATAZANAVIR, AIDS, HYDROLASE, PROTEASE
3el0:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF THE INHIBITOR NELFINAVIR (NFV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10I/G48V/I54V/V64I/V82A) (REFER: FLAP+ IN CITATION) | HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, NELFINAVIR, AIDS, HYDROLASE
3el1:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV PROTEASE IN COMPLEX WITH THE INHIBITOR, ATAZANAVIR | HIV PROTEASE, PROTEASE INHIBITORS, DRUG RESISTANCE, ATAZANAVIR, AIDS, HYDROLASE, PROTEASE
3el5:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF NELFINAVIR (NFV) COMPLEXED WITH A MULTIDRUG VARIANT (ACT) (V82T/I84V) OF HIV-1 PROTEASE | PROTEASE INHIBITOR, DRUG RESISTANCE, NELFINAVIR, HIV-1 PROTEASE, ENTROPY-ENTHALPY COMPENSATION, HYDROLASE
3el5:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF NELFINAVIR (NFV) COMPLEXED WITH A MULTIDRUG VARIANT (ACT) (V82T/I84V) OF HIV-1 PROTEASE | PROTEASE INHIBITOR, DRUG RESISTANCE, NELFINAVIR, HIV-1 PROTEASE, ENTROPY-ENTHALPY COMPENSATION, HYDROLASE
3el9:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF ATAZANAVIR (ATV) IN COMPLEX WITH A MULTIDRUG HIV- 1 PROTEASE (V82T/I84V) | DRUG RESISTANCE, ENTROPY ENTHALPY COMPENSATION, HIV PROTEASE, ATAZANAVIR, AIDS, HYDROLASE
3el9:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF ATAZANAVIR (ATV) IN COMPLEX WITH A MULTIDRUG HIV- 1 PROTEASE (V82T/I84V) | DRUG RESISTANCE, ENTROPY ENTHALPY COMPENSATION, HIV PROTEASE, ATAZANAVIR, AIDS, HYDROLASE
2b60:B (PRO9) to (GLU34) STRUCTURE OF HIV-1 PROTEASE MUTANT BOUND TO RITONAVIR | HIV-1 PROTEASE, PROTEASE INHIBITORS, RITONAVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3em3:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF AMPRENAVIR (APV) IN COMPLEX WITH A DRUG RESISTANT HIV-1 PROTEASE VARIANT (I50L/A71V). | PROTEASE INHIBITOR, HYPER SUSCEPTIBILITY, DRUG RESISTANCE, HIV, AMPRENAVIR, AIDS, HYDROLASE, PROTEASE
3em4:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF ATAZANAVIR (ATV) IN COMPLEX WITH I50L/A71V DRUG- RESISTANT HIV-1 PROTEASE | DRUG RESISTANCE, HYPERSUSCEPTIBILITY, PROTEASE INHIBITOR, HIV, ATAZANAVIR, AIDS, HYDROLASE, PROTEASE
3em4:U (VAL11) to (GLU34) CRYSTAL STRUCTURE OF ATAZANAVIR (ATV) IN COMPLEX WITH I50L/A71V DRUG- RESISTANT HIV-1 PROTEASE | DRUG RESISTANCE, HYPERSUSCEPTIBILITY, PROTEASE INHIBITOR, HIV, ATAZANAVIR, AIDS, HYDROLASE, PROTEASE
3em4:V (VAL11) to (GLU34) CRYSTAL STRUCTURE OF ATAZANAVIR (ATV) IN COMPLEX WITH I50L/A71V DRUG- RESISTANT HIV-1 PROTEASE | DRUG RESISTANCE, HYPERSUSCEPTIBILITY, PROTEASE INHIBITOR, HIV, ATAZANAVIR, AIDS, HYDROLASE, PROTEASE
3em6:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF I50L/A71V MUTANT OF HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR DARUNAVIR | PROTEASE INHIBITOR, HYPER SUSCEPTIBILITY, DRUG RESISTANCE, HIV, DARUNAVIR, AIDS, HYDROLASE, PROTEASE
3em6:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF I50L/A71V MUTANT OF HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR DARUNAVIR | PROTEASE INHIBITOR, HYPER SUSCEPTIBILITY, DRUG RESISTANCE, HIV, DARUNAVIR, AIDS, HYDROLASE, PROTEASE
1nu8:A (ASN263) to (THR307) CRYSTAL STRUCTURE OF HUMAN DIPEPTIDYL PEPTIDASE IV (DPP-IV) IN COMPLEX WITH DIPROTIN A (IPI) | B-BARREL, ALPHA/BETA HYDROLASE FOLD, EXOPEPTIDASE, DIPROTIN A, HYDROLASE
1nu8:B (THR265) to (THR307) CRYSTAL STRUCTURE OF HUMAN DIPEPTIDYL PEPTIDASE IV (DPP-IV) IN COMPLEX WITH DIPROTIN A (IPI) | B-BARREL, ALPHA/BETA HYDROLASE FOLD, EXOPEPTIDASE, DIPROTIN A, HYDROLASE
1nv1:A (CYS1092) to (PHE1117) FRUCTOSE-1,6-BISPHOSPHATASE COMPLEX WITH MAGNESIUM, FRUCTOSE-6- PHOSPHATE, PHOSPHATE AND THALLIUM (5 MM) | BISPHOSPHATASE, ALLOSTERIC ENZYMES, GLUCONEOGENESIS, HYDROLASE
1nv5:A (CYS1092) to (PHE1117) FRUCTOSE-1,6-BISPHOSPHATASE COMPLEX WITH MAGNESIUM, FRUCTOSE-6- PHOSPHATE, PHOSPHATE, EDTA AND THALLIUM (5 MM) | BISPHOSPHATASE, ALLOSTERIC ENZYMES, GLUCONEOGENESIS, HYDROLASE
1nv6:A (CYS1092) to (PHE1117) FRUCTOSE-1,6-BISPHOSPHATASE COMPLEX WITH MAGNESIUM, FRUCTOSE-6- PHOSPHATE, PHOSPHATE, EDTA AND THALLIUM (20 MM) | BISPHOSPHATASE, ALLOSTERIC ENZYMES, GLUCONEOGENESIS, HYDROLASE
1nv7:A (CYS1092) to (PHE1117) FRUCTOSE-1,6-BISPHOSPHATASE COMPLEX WITH AMP, MAGNESIUM, FRUCTOSE-6-PHOSPHATE, PHOSPHATE AND THALLIUM (20 MM) | BISPHOSPHATASE, ALLOSTERIC ENZYMES, GLUCONEOGENESIS, HYDROLASE
2b7z:B (PRO9) to (GLU34) STRUCTURE OF HIV-1 PROTEASE MUTANT BOUND TO INDINAVIR | HIV-1, PROTEASE, INDINAVIR, DRUG RESISTANCE, ACTIVE SITE MUTATIONS, NON-ACTIVE SITE MUTATIONS,VIRAL PROTEIN, VIRAL PROTEIN
2bb9:A (VAL11) to (GLU34) STRUCTURE OF HIV1 PROTEASE AND AKC4P_133A COMPLEX. | PROTEASE, HYDROLASE
2bb9:B (VAL211) to (GLU234) STRUCTURE OF HIV1 PROTEASE AND AKC4P_133A COMPLEX. | PROTEASE, HYDROLASE
2bbb:B (VAL211) to (GLU234) STRUCTURE OF HIV1 PROTEASE AND HH1_173_3A COMPLEX. | PROTEASE, HYDROLASE
2p3b:A (ARG8) to (GLU34) CRYSTAL STRUCTURE OF THE SUBTYPE B WILD TYPE HIV PROTEASE COMPLEXED WITH TL-3 INHIBITOR | WILD TYPE SUBTYPE B HIV PROTEASE, TL-3 INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4hcx:B (THR154) to (PHE188) STRUCTURE OF ICDH-1 FROM M.TUBERCULOSIS COMPLEXED WITH NADPH & MN2+ | ICDH-1, ROSSMANN FOLD, DEHYDROGENASE, NADP BINDING, OXIDOREDUCTASE
4hdb:B (ARG108) to (GLU134) CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANTS D30N COMPLEXED WITH INHIBITOR GRL-0519 | ASPARTIC ACID PROTEASE, DRUG RESISTANCE, HIV-1 PROTEASE INHIBITOR GRL-0519, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4hdp:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANTS I50V COMPLEXED WITH INHIBITOR GRL-0519 | ASPARTIC ACID PROTEASE, DRUG RESISTANCE, HIV-1 PROTEASE INHIBITOR GRL-0519, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4he0:A (CYS92) to (PHE117) CRYSTAL STRUCTURE OF HUMAN MUSCLE FRUCTOSE-1,6-BISPHOSPHATASE | ALLOSTERIC ENZYME, HYDROLASE
1b6j:A (VAL11) to (GLU34) HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 1 | COMPLEX (ACID PROTEINASE-PEPTIDE), HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ba9:A (GLY85) to (VAL119) THE SOLUTION STRUCTURE OF REDUCED MONOMERIC SUPEROXIDE DISMUTASE, NMR, 36 STRUCTURES | OXIDOREDUCTASE, SUPEROXIDE DISMUTASE, COPPER-ZINC ENZYME, DISMUTATION OF UPEROXIDE RADICALS TO MOLECULAR OXYGEN AND HYDROGEN PEROXIDE
2bgj:A (GLU48) to (PRO85) X-RAY STRUCTURE OF THE FERREDOXIN-NADP(H) REDUCTASE FROM RHODOBACTER CAPSULATUS AT 2.1 ANGSTROMS | FERREDOXIN(FLAVODOXIN)-NADP(H) REDUCTASE, FLAVOPROTEINS, ELECTRON TRANSFER, RHODOBACTER CAPSULATUS, OXIDOREDUCTASE
4hi6:A (TRP19) to (GLY69) CRYSTAL STRUCTURE OF H112W MUTANT OF BORNA DISEASE VIRUS MATRIX PROTEIN | VIRAL MATRIX PROTEIN, RNA BINDING, MEMBRANE BINDING,VIRUSES, SSRNA NEGATIVE-STRAND VIRUSES, MONONEGAVIRALES;BORNAVIRIDAE, BORNAVIRUS, VIRION, VIRAL PROTEIN
4hit:C (TRP19) to (GLY69) CRYSTAL STRUCTURE OF H112W MUTANT OF BORNA DISEASE VIRUS MATRIX PROTEIN | VIRAL MATRIX PROTEIN, RNA BINDING, MEMBRANE BINDING, VIRUSES, SSRNA, NEGATIVE-STRAND VIRUSES, MONONEGAVIRALES, BORNAVIRIDAE, BORNA VIRUS, VIRION, VIRAL PROTEIN
3s43:A (THR12) to (GLU34) HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH ANTIVIRAL DRUG AMPRENAVIR | AMPRENAVIR, HIV/AIDS, DRUG RESISTANCE, ASPARTIC PROTEASE, MOLECULAR RECOGNITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4hla:A (PRO9) to (GLU34) CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH DARUNAVIR | DARUNAVIR, PROTEASE, HYDROLASE, GAG, GAG-POL, TMC114, UIC-94017, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4hla:B (PRO9) to (GLU34) CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH DARUNAVIR | DARUNAVIR, PROTEASE, HYDROLASE, GAG, GAG-POL, TMC114, UIC-94017, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4hmw:A (LEU51) to (HIS80) CRYSTAL STRUCTURE OF PHZG FROM BURKHOLDERIA LATA 383 | APO STRUCTURE, OXIDOREDUCTASE
4hmx:A (LEU51) to (HIS80) CRYSTAL STRUCTURE OF PHZG FROM BURKHOLDERIA LATA 383 IN COMPLEX WITH TETRAHYDROPHENAZINE-1-CARBOXYLIC ACID | APO STRUCTURE, OXIDOREDUCTASE
4hmx:B (LEU51) to (HIS80) CRYSTAL STRUCTURE OF PHZG FROM BURKHOLDERIA LATA 383 IN COMPLEX WITH TETRAHYDROPHENAZINE-1-CARBOXYLIC ACID | APO STRUCTURE, OXIDOREDUCTASE
3s56:B (ARG8) to (GLU34) HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH ANTIVIRAL DRUG SAQUINAVIR | SAQUINAVIR,HIV/AIDS, DRUG RESISTANCE, ASPARTIC PROTEASE, MOLECULAR RECOGNITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2bpv:A (ARG8) to (GLU34) HIV-1 PROTEASE-INHIBITOR COMPLEX | ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2bpv:B (VAL11) to (GLU34) HIV-1 PROTEASE-INHIBITOR COMPLEX | ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2bpw:A (VAL11) to (GLU34) HIV-1 PROTEASE-INHIBITOR COMPLEX | ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2bpx:B (PRO9) to (GLU34) HIV-1 PROTEASE-INHIBITOR COMPLEX | ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2bpy:A (ARG8) to (GLU34) HIV-1 PROTEASE-INHIBITOR COMPLEX | ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2bpz:A (ARG8) to (GLU34) HIV-1 PROTEASE-INHIBITOR COMPLEX | ACID PROTEASE, HYDROLASE-HYDROLASE COMPLEX
3s85:A (VAL11) to (GLU34) DISCOVERY OF NEW HIV PROTEASE INHIBITORS WITH POTENTIAL FOR CONVENIENT DOSING AND REDUCED SIDE EFFECTS: A-790742 AND A-792611. | BETA BARREL, ACID PROTEASE, ASPARTIC-TYPE ENDOPEPIDASE ACTIVITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3s85:E (ARG8) to (GLU34) DISCOVERY OF NEW HIV PROTEASE INHIBITORS WITH POTENTIAL FOR CONVENIENT DOSING AND REDUCED SIDE EFFECTS: A-790742 AND A-792611. | BETA BARREL, ACID PROTEASE, ASPARTIC-TYPE ENDOPEPIDASE ACTIVITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3s85:F (VAL11) to (GLU34) DISCOVERY OF NEW HIV PROTEASE INHIBITORS WITH POTENTIAL FOR CONVENIENT DOSING AND REDUCED SIDE EFFECTS: A-790742 AND A-792611. | BETA BARREL, ACID PROTEASE, ASPARTIC-TYPE ENDOPEPIDASE ACTIVITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3s85:G (VAL11) to (GLU34) DISCOVERY OF NEW HIV PROTEASE INHIBITORS WITH POTENTIAL FOR CONVENIENT DOSING AND REDUCED SIDE EFFECTS: A-790742 AND A-792611. | BETA BARREL, ACID PROTEASE, ASPARTIC-TYPE ENDOPEPIDASE ACTIVITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3s85:J (VAL11) to (GLU34) DISCOVERY OF NEW HIV PROTEASE INHIBITORS WITH POTENTIAL FOR CONVENIENT DOSING AND REDUCED SIDE EFFECTS: A-790742 AND A-792611. | BETA BARREL, ACID PROTEASE, ASPARTIC-TYPE ENDOPEPIDASE ACTIVITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3s85:K (VAL11) to (GLU34) DISCOVERY OF NEW HIV PROTEASE INHIBITORS WITH POTENTIAL FOR CONVENIENT DOSING AND REDUCED SIDE EFFECTS: A-790742 AND A-792611. | BETA BARREL, ACID PROTEASE, ASPARTIC-TYPE ENDOPEPIDASE ACTIVITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3s85:L (ARG8) to (GLU34) DISCOVERY OF NEW HIV PROTEASE INHIBITORS WITH POTENTIAL FOR CONVENIENT DOSING AND REDUCED SIDE EFFECTS: A-790742 AND A-792611. | BETA BARREL, ACID PROTEASE, ASPARTIC-TYPE ENDOPEPIDASE ACTIVITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3s8i:B (MET243) to (SER269) THE RETROVIRAL-LIKE PROTEASE (RVP) DOMAIN OF HUMAN DDI1 | PROTEASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, RETROPEPSIN-LIKE DOMAIN, PROTEIN TURNOVER, HYDROLASE
3f8s:A (ASN263) to (THR307) CRYSTAL STRUCTURE OF DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH INHIBITOR | DIPEPTIDYL PEPTIDASE 4, COMPLEX, AMINOPEPTIDASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, SERINE PROTEASE, SIGNAL- ANCHOR, TRANSMEMBRANE
3f8s:B (ASN263) to (THR307) CRYSTAL STRUCTURE OF DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH INHIBITOR | DIPEPTIDYL PEPTIDASE 4, COMPLEX, AMINOPEPTIDASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, SERINE PROTEASE, SIGNAL- ANCHOR, TRANSMEMBRANE
1bte:A (GLN9) to (SER49) CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF THE TYPE II ACTIVIN RECEPTOR | RECEPTOR, SERINE KINASE, LIGAND BINDING DOMAIN, THREE-FINGER TOXIN, TRANSFERASE
1bv7:B (PRO9) to (GLU34) COUNTERACTING HIV-1 PROTEASE DRUG RESISTANCE: STRUCTURAL ANALYSIS OF MUTANT PROTEASES COMPLEXED WITH XV638 AND SD146, CYCLIC UREA AMIDES WITH BROAD SPECIFICITIES | HYDROLASE(ACID PROTEINASE)
2btv:C (ALA148) to (ASP170) ATOMIC MODEL FOR BLUETONGUE VIRUS (BTV) CORE | VIRUS/VIRAL PROTEIN, ICOSAHEDRAL VIRUS
2btv:Q (ALA148) to (ASP170) ATOMIC MODEL FOR BLUETONGUE VIRUS (BTV) CORE | VIRUS/VIRAL PROTEIN, ICOSAHEDRAL VIRUS
2btv:R (ALA148) to (ASP170) ATOMIC MODEL FOR BLUETONGUE VIRUS (BTV) CORE | VIRUS/VIRAL PROTEIN, ICOSAHEDRAL VIRUS
2btv:H (ALA148) to (ASP170) ATOMIC MODEL FOR BLUETONGUE VIRUS (BTV) CORE | VIRUS/VIRAL PROTEIN, ICOSAHEDRAL VIRUS
2btv:S (ALA148) to (ASP170) ATOMIC MODEL FOR BLUETONGUE VIRUS (BTV) CORE | VIRUS/VIRAL PROTEIN, ICOSAHEDRAL VIRUS
2btv:I (ALA148) to (ASP170) ATOMIC MODEL FOR BLUETONGUE VIRUS (BTV) CORE | VIRUS/VIRAL PROTEIN, ICOSAHEDRAL VIRUS
2btv:J (ALA148) to (ASP170) ATOMIC MODEL FOR BLUETONGUE VIRUS (BTV) CORE | VIRUS/VIRAL PROTEIN, ICOSAHEDRAL VIRUS
2btv:T (ALA148) to (ASP170) ATOMIC MODEL FOR BLUETONGUE VIRUS (BTV) CORE | VIRUS/VIRAL PROTEIN, ICOSAHEDRAL VIRUS
1bw8:A (PRO286) to (LYS319) MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH EGFR INTERNALIZATION PEPTIDE FYRALM | ENDOCYTOSIS, ADAPTOR, PEPTIDE COMPLEX, PEPTIDE BINDING PROTEIN
1ob9:A (LYS81) to (THR110) HOLLIDAY JUNCTION RESOLVING ENZYME | HYDROLASE, ENZYME, HOMOLOGOUS RECOMBINATION, HOLLIDAY JUNCTION RESOLVING ENZYME, NUCLEASE, ARCHAEA, THERMOPHILE
3sa7:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF55 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3sa7:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF55 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3sab:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF78 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1bxx:A (ASN171) to (ASN217) MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH TGN38 INTERNALIZATION PEPTIDE DYQRLN | ENDOCYTOSIS, ADAPTOR, PEPTIDE COMPLEX, ENDOCYTOSIS/EXOCYTOSIS COMPLEX
1bxx:A (PRO286) to (LYS319) MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH TGN38 INTERNALIZATION PEPTIDE DYQRLN | ENDOCYTOSIS, ADAPTOR, PEPTIDE COMPLEX, ENDOCYTOSIS/EXOCYTOSIS COMPLEX
1ogo:X (ASP364) to (ASP388) DEX49A FROM PENICILLIUM MINIOLUTEUM COMPLEX WITH ISOMALTOSE | HYDROLASE, DEXTRAN DEGRADATION, GLYCOSIDASE
2bzu:A (ALA250) to (ASP291) HUMAN ADENOVIRUS SEROTYPE 41 FIBER HEAD | ADENOVIRUS, FIBER, RECEPTOR, AD41, FIBER PROTEIN, VIRAL PROTEIN
2bzv:A (ALA250) to (ASP291) HUMAN ENTERIC ADENOVIRUS SEROTYPE 41 SHORT FIBER HEAD (PH8) | ADENOVIRUS, FIBER, RECEPTOR, AD41, FIBER PROTEIN, VIRAL PROTEIN
1c6y:A (VAL11) to (GLU34) ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP. | HYDROLASE
1c6y:B (THR212) to (GLU234) ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP. | HYDROLASE
4xgo:A (SER173) to (PRO197) CRYSTAL STRUCTURE OF LEUCINE-RICH REPEAT DOMAIN OF APL1B | PROTEIN BINDING
4xgo:B (SER173) to (PRO197) CRYSTAL STRUCTURE OF LEUCINE-RICH REPEAT DOMAIN OF APL1B | PROTEIN BINDING
4xhb:A (TYR458) to (GLY493) CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH PENTANEDIOL AND CHES | HYDROLASE, INTRAMOLECULAR TRANS-SIALIDASE, GLYCOSIDASE, DRUG DESIGN, NEURAMINIDASE, ALLOSTERIC INHIBITOR, SERENDIPITOUS ALLOSTERIC SITES, CRYSTALLIZATION ARTEFACTS
1ohr:A (VAL11) to (GLU34) VIRACEPT (R) (NELFINAVIR MESYLATE, AG1343): A POTENT ORALLY BIOAVAILABLE INHIBITOR OF HIV-1 PROTEASE | ASPARTYL PROTEASE, HYDROLASE, HIV-I PROTEASE
1ohr:B (ARG8) to (GLU34) VIRACEPT (R) (NELFINAVIR MESYLATE, AG1343): A POTENT ORALLY BIOAVAILABLE INHIBITOR OF HIV-1 PROTEASE | ASPARTYL PROTEASE, HYDROLASE, HIV-I PROTEASE
2pqz:B (VAL11) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH A PYRROLIDINE-BASED INHIBITOR | PROTEIN-LIGAND COMPLEX, HYDROLASE
2pr9:A (PRO286) to (LYS319) MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH GABAA RECEPTOR-GAMMA2 SUBUNIT-DERIVED INTERNALIZATION PEPTIDE DEEYGYECL | ENDOCYTOSIS, ADAPTOR, INTERNALIZATION PEPTIDE COMPLEX, INHIBITORY NEUROTRANSMITTER RECEPTOR
2psu:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH CARB- AD37 | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITOR, HYDROLASE
2psu:B (ARG8) to (GLU34) CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH CARB- AD37 | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITOR, HYDROLASE
2psv:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH CARB- KB45 | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
4xjz:A (TYR458) to (GLY493) CRYSTAL STRUCTURE OF APO NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE AT PH 7.4 IN PBS WITH DMSO | HYDROLASE, INTRAMOLECULAR TRANS-SIALIDASE, GLYCOSIDASE, DRUG DESIGN, NEURAMINIDASE, ALLOSTERIC INHIBITOR, SERENDIPITOUS ALLOSTERIC SITES, CRYSTALLIZATION ARTEFACTS
3flq:A (THR7) to (GLY31) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH 6-(2,4- DIFLUORO-PHENOXY)-2-((S)-2-METHANESULFONYL-1-METHYL- ETHYLAMINO)-8-METHYL-8H-PYRIDO[2,3-D]PYRIMIDIN | P38; MAP KINASE; SERINE/THREONINE KINASE, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, SIGNALING PROTEIN
3fly:A (THR7) to (GLY31) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH 6-(2,4- DIFLUORO-PHENOXY)-2-ISOPROPYLAMINO-8-METHYL-8H-PYRIDO[2,3- D]PYRIMIDIN-7-ONE | P38; MAP KINASE; SERINE/THREONINE KINASE, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, SIGNALING PROTEIN
3flz:A (THR7) to (GLY31) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH 8-METHYL-6-PHENOXY-2- (TETRAHYDRO-PYRAN-4-YLAMINO)-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE | P38; MAP KINASE; SERINE/THREONINE KINASE, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE, SIGNALING PROTEIN
2pwc:B (ARG8) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH A AMINO DECORATED PYRROLIDINE-BASED INHIBITOR | PROTEIN-LIGAND COMPLEX, HYDROLASE
3fnk:B (THR13) to (ASP49) CRYSTAL STRUCTURE OF THE SECOND TYPE II COHESIN MODULE FROM THE CELLULOSOMAL ADAPTOR SCAA SCAFFOLDIN OF ACETIVIBRIO CELLULOLYTICUS | COHB, DOCKERIN-BINDING MODULE, BETA BARREL, ALPHA HELIX, BETA FLAPS, STRUCTURAL PROTEIN
2pwr:B (VAL11) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH A CARBAMOYL DECORATED PYRROLIDINE-BASED INHIBITOR | PROTEIN-LIGAND COMPLEX, HYDROLASE
4i6l:A (SER230) to (PRO263) CRYSTAL STRUCTURE OF OTUB1 IN COMPLEX WITH UBIQUITIN VARIANT | DEUBIQUITINASE, HYDROLASE
2pyn:A (PRO9) to (GLU34) HIV-1 PR MUTANT IN COMPLEX WITH NELFINAVIR | RESISTANCE; NELFINAVIR, HYDROLASE
2pyn:B (ARG8) to (GLU34) HIV-1 PR MUTANT IN COMPLEX WITH NELFINAVIR | RESISTANCE; NELFINAVIR, HYDROLASE
4i8w:B (PRO9) to (GLU34) CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH NON- PEPTIDIC INHIBITOR, GRL007 | HIV-1 PROTEASE, HIV-1 PROTEASE-INHIBITOR COMPLEX, HYDROLASE, GRL007, PROTEASE INHIBITOR, NON-PEPTIDIC PROTEASE INHIBITOR, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
2c6g:A (TYR127) to (GLY172) MEMBRANE-BOUND GLUTAMATE CARBOXYPEPTIDASE II (GCPII) WITH BOUND GLUTAMATE | NAALADASE, NEURODEGENERATIVE DISEASE, PEPTIDASE, PROSTATE CANCER, PSMA, GLYCOPROTEIN, HYDROLASE, ALTERNATIVE SPLICING, ANTIGEN, CARBOXYPEPTIDASE, DIPEPTIDASE, METAL-BINDING, METALLOPROTEASE, MULTIFUNCTIONAL ENZYME, POLYMORPHISM, SIGNAL-ANCHOR, TRANSMEMBRANE, ZINC
1cnq:A (CYS92) to (PHE117) FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH FRUCTOSE-6-PHOSPHATE AND ZINC IONS | BISPHOSPHATASE, HYDROLASE
4xlq:B (THR97) to (ASN124) CRYSTAL STRUCTURE OF T.AQUATICUS TRANSCRIPTION INITIATION COMPLEX CONTAINING UPSTREAM FORK (-11 BASE-PAIRED) PROMOTER | PROTEIN-DNA COMPLEX, BACTERIAL TRANSCRIPTION INITIATION COMPLEX, TRANSCRIPTION-DNA COMPLEX
4xlq:H (THR97) to (ASN124) CRYSTAL STRUCTURE OF T.AQUATICUS TRANSCRIPTION INITIATION COMPLEX CONTAINING UPSTREAM FORK (-11 BASE-PAIRED) PROMOTER | PROTEIN-DNA COMPLEX, BACTERIAL TRANSCRIPTION INITIATION COMPLEX, TRANSCRIPTION-DNA COMPLEX
2q54:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF KB73 BOUND TO HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2q55:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF KK44 BOUND TO HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITOR, HYDROLASE
1cvm:A (GLY125) to (GLY160) CADMIUM INHIBITED CRYSTAL STRUCTURE OF PHYTASE FROM BACILLUS AMYLOLIQUEFACIENS | THERMOSTABLE BACILLUS PHYTASE PHYTATE PHOSPHATASE CADMIUM CALCIUM, HYDROLASE
2q5k:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF LOPINAVIR BOUND TO WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2q63:A (PRO9) to (GLU34) HIV-1 PR MUTANT IN COMPLEX WITH NELFINAVIR | RESISTANCE; NELFINAVIR, HYDROLASE
2q63:B (PRO9) to (GLU34) HIV-1 PR MUTANT IN COMPLEX WITH NELFINAVIR | RESISTANCE; NELFINAVIR, HYDROLASE
1p0k:A (ILE45) to (ALA62) IPP:DMAPP ISOMERASE TYPE II APO STRUCTURE | TERPENE BIOSYNTHESIS, ISOPENTENYL DIPHOSPHATE, DIMETHYLALLYL DIPHOSPHATE, ISOMERASE, FLAVOPROTEIN
1p0k:B (ILE45) to (ALA62) IPP:DMAPP ISOMERASE TYPE II APO STRUCTURE | TERPENE BIOSYNTHESIS, ISOPENTENYL DIPHOSPHATE, DIMETHYLALLYL DIPHOSPHATE, ISOMERASE, FLAVOPROTEIN
1p0n:B (ILE45) to (ALA62) IPP:DMAPP ISOMERASE TYPE II, FMN COMPLEX | TERPENE BIOSYNTHESIS, ISOPENTENYL DIPHOSPHATE, DIMETHYLALLYL DIPHOSPHATE, ISOMERASE, FLAVOPROTEIN
1czf:A (ASN52) to (GLY76) ENDO-POLYGALACTURONASE II FROM ASPERGILLUS NIGER | BETA HELIX, HYDROLASE
1czf:B (ASN52) to (GLY76) ENDO-POLYGALACTURONASE II FROM ASPERGILLUS NIGER | BETA HELIX, HYDROLASE
2qak:B (ARG8) to (GLU34) HIV-1 PR MUTANT IN COMPLEX WITH NELFINAVIR | HIV PROTEASE INHIBITORS; PROTEASE-INHIBITOR STRUCTURE; ISOTHERMAL CALORIMETRY; ANTIVIRAL RESISTANCE DEVELOPMENT, HYDROLASE
1d4j:B (VAL111) to (GLU134) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR MSL370 | DIMER, HYDROLASE
2qd8:B (VAL111) to (GLU134) HIV-1 PROTEASE MUTANT I84V WITH POTENT ANTIVIRAL INHIBITOR GRL-98065 | HIV-1 PROTEASE MUTANT I84V, PROTEASE INHIBITOR, HYDROLASE
3syo:A (LEU205) to (LEU243) CRYSTAL STRUCTURE OF THE G PROTEIN-GATED INWARD RECTIFIER K+ CHANNEL GIRK2 (KIR3.2) IN COMPLEX WITH SODIUM | ION CHANNEL, POTASSIUM CHANNEL, INWARD RECTIFICATION, SODIUM BINDING, PIP2 BINDING, G PROTEIN BINDING, METAL TRANSPORT
2cge:A (ILE341) to (GLU372) CRYSTAL STRUCTURE OF AN HSP90-SBA1 CLOSED CHAPERONE COMPLEX | CHAPERONE COMPLEX, HSP90, HEAT SHOCK PROTEIN, CO-CHAPERONE, ATP-BINDING, CHAPERONE, HEAT SHOCK, NUCLEOTIDE-BINDING
2qfw:B (GLY151) to (THR187) CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVESIAE MITOCHONDRIAL NADP(+)- DEPENDENT ISOCITRATE DEHYDROGENASE IN COMPLEX WITH ISOCITRATE | ROSSMANN FOLD, OXIDOREDUCTASE
2qfy:B (GLY151) to (THR187) CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVESIAE MITOCHONDRIAL NADP(+)- DEPENDENT ISOCITRATE DEHYDROGENASE IN COMPLEX WITH A-KETOGLUTARATE | ROSSMANN FOLD, OXIDOREDUCTASE
2qgo:A (ILE25) to (SER77) CRYSTAL STRUCTURE OF A PUTATIVE FE-S BIOSYNTHESIS PROTEIN FROM LACTOBACILLUS ACIDOPHILUS | PSI-2, NYSGXRC, 10399G, FE-S CLUSTER PROTEIN, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, BIOSYNTHETIC PROTEIN
2qhc:B (ARG8) to (GLU34) THE INFLUENCE OF I47A MUTATION ON REDUCED SUSCEPTIBILITY TO THE PROTEASE INHIBITOR LOPINAVIR | HIV PROTEASE INHIBITORS; PROTEASE-INHIBITOR STRUCTURE; ASPARTIC PROTEASE, RESISTANT STRAIN, HYDROLASE
2qi0:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-1-KK80 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2qi5:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-2-KC08 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2qi5:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-2-KC08 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2qi6:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-2-KB98 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2qj9:D (PHE35) to (GLU64) CRYSTAL STRUCTURE ANALYSIS OF BMP-2 IN COMPLEX WITH BMPR-IA VARIANT B1 | LIGAND-RECEPTOR COMPLEX, CHONDROGENESIS, CLEAVAGE ON PAIR OF BASIC RESIDUES, CYTOKINE, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, GLYCOPROTEIN, GROWTH FACTOR, OSTEOGENESIS, ATP-BINDING, DISEASE MUTATION, KINASE, MAGNESIUM, MANGANESE, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PHOSPHORYLATION, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, TRANSMEMBRANE, CYTOKINE-RECEPTOR COMPLEX
2qja:D (PHE35) to (GLU64) CRYSTAL STRUCTURE ANALYSIS OF BMP-2 IN COMPLEX WITH BMPR-IA VARIANT B12 | LIGAND-RECEPTOR COMPLEX, CHONDROGENESIS, CLEAVAGE ON PAIR OF BASIC RESIDUES, CYTOKINE, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, GLYCOPROTEIN, GROWTH FACTOR, OSTEOGENESIS, ATP-BINDING, DISEASE MUTATION, KINASE, MAGNESIUM, MANGANESE, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PHOSPHORYLATION, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, TRANSMEMBRANE, CYTOKINE-RECEPTOR COMPLEX
1pfq:A (ASN263) to (THR307) CRYSTAL STRUCTURE OF HUMAN APO DIPEPTIDYL PEPTIDASE IV / CD26 | MCH_1, HYDROLASE
2qmp:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH PL-100 | HIV-1 PROTEASE, ASPARTYL PROTEASE, HYDROLASE, MULTIFUNCTIONAL ENZYME, NUCLEOTIDYLTRANSFERASE, RNA- DIRECTED DNA POLYMERASE, TRANSFERASE
3t2p:C (PHE626) to (ALA657) E. COLI (LACZ) BETA-GALACTOSIDASE (S796D) IN COMPLEX WITH IPTG | DYNAMIC LOOP CONFORMATION, SER-796, TIM BARREL (ALPHA/BETA BARREL), JELLY-ROLL BARREL, IMMUNOGLOBULIN, BETA SUPERSANDWICH, GLYCOSIDASE, HYDROLASE
3t2p:D (PHE626) to (ALA657) E. COLI (LACZ) BETA-GALACTOSIDASE (S796D) IN COMPLEX WITH IPTG | DYNAMIC LOOP CONFORMATION, SER-796, TIM BARREL (ALPHA/BETA BARREL), JELLY-ROLL BARREL, IMMUNOGLOBULIN, BETA SUPERSANDWICH, GLYCOSIDASE, HYDROLASE
2qnn:B (VAL11) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH A MULTIPLE DECORATED PYRROLIDINE-BASED INHIBITOR | PROTEIN-LIGAND COMPLEX, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, PHOSPHORYLATION, PROTEASE, RNA- BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC-FINGER
2qnp:B (VAL11) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH A IODO DECORATED PYRROLIDINE- BASED INHIBITOR | PROTEIN-LIGAND COMPLEX, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, PHOSPHORYLATION, PROTEASE, RNA- BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER
2qnq:B (ARG8) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH A CHLORO DECORATED PYRROLIDINE-BASED INHIBITOR | PROTEIN-LIGAND COMPLEX, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, PHOSPHORYLATION, PROTEASE, RNA- BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER
3gfe:A (PRO6) to (GLY31) CRYSTAL STRUCTURE OF P38A MITOGEN-ACTIVATED PROTEIN KINASE IN COMPLEX WITH A PYRAZOLOPYRIDINONE INHIBITOR | SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM
2qqo:A (GLY473) to (GLY509) CRYSTAL STRUCTURE OF THE A2B1B2 DOMAINS FROM HUMAN NEUROPILIN-2 | VEGF RECEPTOR, SEMAPHORIN RECEPTOR, CALCIUM-BINDING DOMAIN, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, GLYCOPROTEIN, MEMBRANE, NEUROGENESIS, TRANSMEMBRANE, HORMONE, SIGNALING PROTEIN
3gga:G (ARG8) to (GLU34) HIV PROTEASE INHIBITORS WITH PSEUDO-SYMMETRIC CORES | PSEUDO-SYMMETRICAL HIV PROTEASE INHIBITORS, HYDROLASE, PROTEASE
3gga:H (VAL11) to (GLU34) HIV PROTEASE INHIBITORS WITH PSEUDO-SYMMETRIC CORES | PSEUDO-SYMMETRICAL HIV PROTEASE INHIBITORS, HYDROLASE, PROTEASE
3gga:B (VAL11) to (GLU34) HIV PROTEASE INHIBITORS WITH PSEUDO-SYMMETRIC CORES | PSEUDO-SYMMETRICAL HIV PROTEASE INHIBITORS, HYDROLASE, PROTEASE
3gga:D (VAL11) to (GLU34) HIV PROTEASE INHIBITORS WITH PSEUDO-SYMMETRIC CORES | PSEUDO-SYMMETRICAL HIV PROTEASE INHIBITORS, HYDROLASE, PROTEASE
3ggv:A (VAL11) to (GLU34) HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS | HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE
3ggv:F (VAL11) to (GLU34) HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS | HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE
3ggv:H (VAL11) to (GLU34) HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS | HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE
3ggv:I (VAL11) to (GLU34) HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS | HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE
3gi4:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, KB60 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, PROTEASE INHIBITORS, HIV-1 PROTEASE, ASPARTYL PROTEASE, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3gi6:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, AD78 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, PROTEASE INHIBITORS, HIV-1 PROTEASE, ASPARTYL PROTEASE, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3gi6:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, AD78 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, PROTEASE INHIBITORS, HIV-1 PROTEASE, ASPARTYL PROTEASE, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2qt9:A (PRO264) to (THR307) HUMAN DIPEPTIDYL PEPTIDASE IV/CD26 IN COMPLEX WITH A 4-ARYL CYCLOHEXYLALANINE INHIBITOR | ALPHA/BETA, BETA-PROPELLER, DIMER, AMINOPEPTIDASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, SERINE PROTEASE, SIGNAL- ANCHOR, TRANSMEMBRANE
2qtb:A (ASN263) to (THR307) HUMAN DIPEPTIDYL PEPTIDASE IV/CD26 IN COMPLEX WITH A 4-ARYL CYCLOHEXYLALANINE INHIBITOR | ALPHA/BETA, BETA-PROPELLER, DIMER, AMINOPEPTIDASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, SERINE PROTEASE, SIGNAL- ANCHOR, TRANSMEMBRANE
2d3v:A (ASN99) to (ARG129) CRYSTAL STRUCTURE OF LEUKOCYTE IG-LIKE RECEPTOR A5 (LILRA5/LIR9/ILT11) | IMMUNOGLOBULIN-LIKE FOLD, IMMUNE SYSTEM
2d4l:A (GLY168) to (GLN199) CRYSTAL STRUCTURE OF TRUNCATED IN C-TERMINAL M-PMV DUTPASE | JELLY ROLL, HYDROLASE
2qzx:A (THR13) to (PRO41) SECRETED ASPARTIC PROTEINASE (SAP) 5 FROM CANDIDA ALBICANS | ASPARTIC PROTEINASE, CANDIDA ALBICANS, ASPARTYL PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, GLYCOPROTEIN, PROTEASE, SECRETED, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2r3t:B (VAL11) to (GLU34) I50V HIV-1 PROTEASE MUTANT IN COMPLEX WITH A CARBAMOYL DECORATED PYRROLIDINE-BASED INHIBITOR | PROTEIN-LIGAND COMPLEX, ASPARTYL PROTEASE, HYDROLASE, PROTEASE
4j7f:A (LEU169) to (PHE193) SET7/9Y335PAF IN COMPLEX WITH TAF10 PEPTIDE AND ADOHCY | SET DOMAIN, LYSINE METHYLTRANSFERASE, Y335PAF MUTATION, TRANSFERASE- PEPTIDE COMPLEX
4j7i:A (LEU169) to (PHE193) SET7/9Y335F IN COMPLEX WITH TAF10 PEPTIDE AND ADOHCY | SET DOMAIN, LYSINE METHYLTRANSFERASE, TRANSFERASE-PEPTIDE COMPLEX
4j8o:A (LEU169) to (PHE193) SET7/9 IN COMPLEX WITH TAF10K189A PEPTIDE AND ADOHCY | SET DOMAIN, LYSINE METHYLTRANSFERASE, TRANSFERASE-PEPTIDE COMPLEX
1eby:A (ARG8) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA369 | DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1eby:B (VAL111) to (GLU134) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA369 | DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3tjo:D (HIS185) to (THR217) HTRA1 CATALYTIC DOMAIN, MUTATIONALLY INACTIVATED | PEPTIDASE, HYDROLASE
3tlh:A (ARG8) to (GLU34) STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITHAN EFFICIENT INHIBITOR OF FIV PR | HIV PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4jdz:B (ILE242) to (SER289) STRUCTURES OF SDRD FROM STAPHYLOCOCCUS AUREUS REVEAL THE MOLECULAR MECHANISM OF HOW THE CELL SURFACE RECEPTORS RECOGNIZE THEIR LIGANDS | RECEPTOR, SURFACE, MSCRAMM, STAPHYLOCOCCUS AUREUS, CELL ADHESION
4jdz:A (ILE242) to (TYR288) STRUCTURES OF SDRD FROM STAPHYLOCOCCUS AUREUS REVEAL THE MOLECULAR MECHANISM OF HOW THE CELL SURFACE RECEPTORS RECOGNIZE THEIR LIGANDS | RECEPTOR, SURFACE, MSCRAMM, STAPHYLOCOCCUS AUREUS, CELL ADHESION
4je0:A (ILE7) to (SER54) STRUCTURES OF SDRD FROM STAPHYLOCOCCUS AUREUS REVEAL THE MOLECULAR MECHANISM OF HOW THE CELL SURFACE RECEPTORS RECOGNIZE THEIR LIGANDS | RECEPTOR, SURFACE, MSCRAMM, STAPHYLOCOCCUS AUREUS, CELL ADHESION
4je0:B (ILE7) to (SER54) STRUCTURES OF SDRD FROM STAPHYLOCOCCUS AUREUS REVEAL THE MOLECULAR MECHANISM OF HOW THE CELL SURFACE RECEPTORS RECOGNIZE THEIR LIGANDS | RECEPTOR, SURFACE, MSCRAMM, STAPHYLOCOCCUS AUREUS, CELL ADHESION
4jf7:D (ILE358) to (GLY397) STRUCTURE OF THE PARAINFLUENZA VIRUS 5 (PIV5) HEMAGGLUTININ- NEURAMINIDASE (HN) ECTODOMAIN | PARAMYXOVIRUS, PIV5, ATTACHMENT PROTEIN, HN, RECEPTOR BINDING PROTEIN, ECTODOMAIN, VIRAL PROTEIN
4jf7:A (MET357) to (GLY397) STRUCTURE OF THE PARAINFLUENZA VIRUS 5 (PIV5) HEMAGGLUTININ- NEURAMINIDASE (HN) ECTODOMAIN | PARAMYXOVIRUS, PIV5, ATTACHMENT PROTEIN, HN, RECEPTOR BINDING PROTEIN, ECTODOMAIN, VIRAL PROTEIN
3tof:B (THR12) to (GLU34) HIV-1 PROTEASE - EPOXYDIC INHIBITOR COMPLEX (PH 6 - ORTHOROMBIC CRYSTAL FORM P212121) | HIV PR, EPOXIDE, IN-CRYSTAL REACTION, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3toh:B (THR12) to (GLU34) HIV-1 PROTEASE - EPOXYDIC INHIBITOR COMPLEX (PH 9 - ORTHOROMBIC CRYSTAL FORM P212121) | HIV PR, EPOXIDE, IN-CRYSTAL REACTION, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1qbr:B (PRO9) to (GLU34) HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY | HYDROLASE (ACID PROTEINASE), ASPARTYL PROTEASE
1qbt:A (PRO9) to (GLU34) HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY | HYDROLASE (ACID PROTEINASE), ASPARTYL PROTEASE
3gza:A (ILE365) to (ASN386) CRYSTAL STRUCTURE OF PUTATIVE ALPHA-L-FUCOSIDASE (NP_812709.1) FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 AT 1.60 A RESOLUTION | NP_812709.1, PUTATIVE ALPHA-L-FUCOSIDASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, HYDROLASE
2rdr:A (ARG178) to (PRO214) CRYSTAL STRUCTURE OF PTLH WITH FE/OXALYLGLYCINE BOUND | DOUBLE STRANDED BARREL HELIX, DIOXYGENASE, OXIDOREDUCTASE
3trl:A (GLY86) to (SER116) CRYSTAL STRUCTURE OF M-PMV DUTPASE POST-INVERSION PRODUCT (DUMP) COMPLEX | JELLY ROLL, HYDROLASE
2rdy:B (LEU694) to (GLY719) CRYSTAL STRUCTURE OF A PUTATIVE GLYCOSIDE HYDROLASE FAMILY PROTEIN FROM BACILLUS HALODURANS | 10436A, PSI-II, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, HYDROLASE
4ydj:I (PHE382) to (SER447) CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY 44- VRC13.01 IN COMPLEX WITH HIV-1 CLADE AE STRAIN 93TH057 GP120 | ANTIBODY, HIV-1, IMMUNE SYSTEM
1qiu:D (ASP418) to (ASP462) A TRIPLE BETA-SPIRAL IN THE ADENOVIRUS FIBRE SHAFT REVEALS A NEW STRUCTURAL MOTIF FOR BIOLOGICAL FIBRES | FIBRE PROTEIN, TRIPLE BETA-SPIRAL, ADENOVIRUS
1qiu:E (ASP418) to (ASP462) A TRIPLE BETA-SPIRAL IN THE ADENOVIRUS FIBRE SHAFT REVEALS A NEW STRUCTURAL MOTIF FOR BIOLOGICAL FIBRES | FIBRE PROTEIN, TRIPLE BETA-SPIRAL, ADENOVIRUS
1qjq:A (HIS339) to (LEU402) FERRIC HYDROXAMATE RECEPTOR FROM ESCHERICHIA COLI (FHUA) | TONB DEPENDENT RECEPTOR, LIPOPOLYSACCHARIDE, FERRICHROME-IRON RECEPTOR, INTEGRAL OUTER MEMBRANE PROTEIN, TONB-DEPENDENT RECEPTOR, SIDEROPHORE RECEPTOR, ACTIVE TRANSPORT, IRON TRANSPORT, SIDEROPHORE-ANTIBIOTIC CONJUGATE
2rkg:B (PRO9) to (GLU34) HIV-1 PR RESISTANT MUTANT + LPV | RESISTENCE, INSERTION, HYDROLASE
4jlg:B (LEU169) to (PHE193) SETD7 IN COMPLEX WITH INHIBITOR (R)-PFI-2 AND S-ADENOSYL-METHIONINE | METHYLTRANSFERASE, SET DOMAIN, HISTONE MODIFICATION, TRANSCRIPTION REGULATION, HISTONE LYSINE METHYLTRANSFERASE, INHIBITOR, S-ADENOSYL- L-METHIONINE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1ev1:2 (VAL13) to (GLY34) ECHOVIRUS 1 | VIRAL COAT PROTEIN, CAPSID, PICORNAVIRUS, ECHOVIRUS, ICOSAHEDRAL VIRUS
1ext:B (GLY18) to (ASN41) EXTRACELLULAR DOMAIN OF THE 55KDA TUMOR NECROSIS FACTOR RECEPTOR. CRYSTALLIZED AT PH3.7 IN P 21 21 21. | BINDING PROTEIN, CYTOKINE, SIGNALLING PROTEIN
4jqt:B (ALA41) to (LEU63) CRYSTAL STRUCTURE OF A PUTATIVE GLYCOSYL HYDROLASE (BT3469) FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 AT 2.49 A RESOLUTION | PF06439 FAMILY PROTEIN, DUF1080, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
1f0l:B (ARG133) to (LEU163) 1.55 ANGSTROM CRYSTAL STRUCTURE OF WILD TYPE DIPHTHERIA TOXIN | BACTERIAL TOXIN, ADP-RIBOSYLATION, TRANSMEMBRANE
2upj:A (PRO9) to (GLU34) HIV-1 PROTEASE COMPLEX WITH U100313 ([3-[[3-[CYCLOPROPYL [4-HYDROXY- 2OXO-6-[1-(PHENYLMETHYL)PROPYL]-2H-PYRAN-3-YL] METHYL]PHENYL]AMINO]- 3-OXO-PROPYL]CARBAMIC ACID TERT-BUTYL ESTER) | HYDROLASE (ACID PROTEASE)
2upj:B (VAL11) to (GLU34) HIV-1 PROTEASE COMPLEX WITH U100313 ([3-[[3-[CYCLOPROPYL [4-HYDROXY- 2OXO-6-[1-(PHENYLMETHYL)PROPYL]-2H-PYRAN-3-YL] METHYL]PHENYL]AMINO]- 3-OXO-PROPYL]CARBAMIC ACID TERT-BUTYL ESTER) | HYDROLASE (ACID PROTEASE)
1f1a:A (GLY85) to (ILE119) CRYSTAL STRUCTURE OF YEAST H48Q CUZNSOD FALS MUTANT ANALOG | FALS, CUZNSOD, LOU GEHRIG'S DISEASE, OXIDOREDUCTASE
3h5b:B (VAL111) to (GLU134) CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE WITH NOVEL P1'-LIGAND GRL-02031 | HIV-1, WILD TYPE PROTEASE, PROTEASE INHIBITOR, P1'-LIGAND, AIDS, HYDROLASE
3h85:A (PRO286) to (LYS319) MOLECULAR BASIS FOR THE ASSOCIATION OF PIPKI GAMMA-P90 WITH THE CLATHRIN ADAPTOR AP-2 | PHOSPHATIDYLINOSITOL 4, 5-BISPHOSPHATE, CLATHRIN, ADAPTOR COMPLEX AP-2, ENDOCYTOSIS, CELL MEMBRANE, COATED PIT, LIPID-BINDING, MEMBRANE, PHOSPHOPROTEIN, DISEASE MUTATION, KINASE, TRANSFERASE
2ead:A (GLU253) to (ALA280) CRYSTAL STRUCTURE OF 1,2-A-L-FUCOSIDASE FROM BIFIDOBACTERIUM BIFIDUM IN COMPLEX WITH SUBSTRATE | FUCOSIDASE, GLYCOSIDE HYDROLASE
1f7a:B (VAL11) to (GLU34) HOW DOES A SYMMETRIC DIMER RECOGNIZE AN ASYMMETRIC SUBSTRATE? A SUBSTRATE COMPLEX OF HIV-1 PROTEASE. | CAPSID, SUBSTRATE RECOGNITION, HYDROLASE
1qxp:B (ALA263) to (TRP293) CRYSTAL STRUCTURE OF A MU-LIKE CALPAIN | M-CALPAIN, MU-CALPAIN, CATALYTIC TRIAD, CA(2+) REQUIREMENT, HYDROLASE CHIMERA
2eep:A (VAL231) to (HIS267) PROLYL TRIPEPTIDYL AMINOPEPTIDASE COMPLEXED WITH AN INHIBITOR | PEPTIDASE FAMILY S9, PROLYL OLIGOPEPTIDASE FAMILY, SERINE PEPTIDASE, INHIBITOR COMPLEX, HYDROLASE
1fbc:A (CYS92) to (LEU120) CRYSTALLOGRAPHIC STUDIES OF THE CATALYTIC MECHANISM OF THE NEUTRAL FORM OF FRUCTOSE-1,6-BISPHOSPHATASE | HYDROLASE(PHOSPHORIC MONOESTER)
3u73:U (ARG53) to (SER101) CRYSTAL STRUCTURE OF STABILIZED HUMAN UPAR MUTANT IN COMPLEX WITH ATF | GLYCOSYLATION, HYDROLASE-HYDROLASE RECEPTOR COMPLEX
3u74:U (ASN52) to (SER101) CRYSTAL STRUCTURE OF STABILIZED HUMAN UPAR MUTANT | GLYCOSYLATION, HYDROLASE RECEPTOR
2uxz:B (VAL111) to (GLU134) TWO-CARBON-ELONGATED HIV-1 PROTEASE INHIBITORS WITH A TERTIARY-ALCOHOL-CONTAINING TRANSITION-STATE MIMIC | HIV-1, PROTEASE, HYDROLASE, INHIBITOR, ASPARTYL PROTEASE
2uy0:B (VAL111) to (GLU134) TWO-CARBON-ELONGATED HIV-1 PROTEASE INHIBITORS WITH A TERTIARY-ALCOHOL-CONTAINING TRANSITION-STATE MIMIC | HIV-1, PROTEASE, HYDROLASE, INHIBITOR, ASPARTYL PROTEASE
2uy6:C (ASP120) to (TYR162) CRYSTAL STRUCTURE OF THE P PILUS ROD SUBUNIT PAPA | DONOR STRAND COMPLEMENTATION, PILI/N-TERMINAL EXTENSION, PILUS BIOGENESIS, DONOR-STRAND EXCHANGE, NTE, DSC, DSE, PAPA, PAPD, FIMBRIA, CHAPERONE
1ffi:C (VAL11) to (GLU34) STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1fgc:C (VAL11) to (GLU34) STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ubm:A (VAL376) to (ALA403) FORMYL-COA:OXALATE COA-TRANSFERASE FROM ACETOBACTER ACETI | TRANSFERASE
1fj9:A (CYS92) to (PHE117) FRUCTOSE-1,6-BISPHOSPHATASE (MUTANT Y57W) PRODUCTS/ZN/AMP COMPLEX (T- STATE) | BISPHOSPHATASE, ALLOSTERIC ENZYMES, GLUCONEOGENESIS, HYDROLASE
4yr8:F (TYR11) to (PRO31) CRYSTAL STRUCTURE OF JNK IN COMPLEX WITH A REGULATOR PROTEIN | KINASE DOMAIN, CATALYTIC DOMAIN, TRANSFERASE-HYDROLASE COMPLEX
3uej:A (GLY258) to (ILE283) STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF AN ANESTHETIC BINDING SITE IN THE SECOND CYSTEINE-RICH DOMAIN OF PROTEIN KINASE CDELTA | PROTEINE KINASE CDELTA, PHOSPHOTRANSFERASE, ANESTHETIC BINDING SITE, METAL BINDING PROTEIN
4k4q:B (THR12) to (GLU34) TL-3 INHIBITED TRP6ALA HIV PROTEASE WITH 3-BROMO-2,6-DIMETHOXYBENZOIC ACID BOUND IN FLAP SITE | FRAGMENT BINDING, EXOSITE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ugi:A (GLY258) to (ILE283) STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF AN ANESTHETIC BINDING SITE IN THE SECOND CYSTEINE-RICH DOMAIN OF PROTEIN KINASE C DELTA | PROTEINE KINASE C DELTA, PHOSPHOTRANSFERASE, ANESTHETIC BINDING SITE, METAL BINDING PROTEIN
3ugl:B (GLY258) to (ILE283) STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF AN ANESTHETIC BINDING SITE IN THE SECOND CYSTEINE-RICH DOMAIN OF PROTEIN KINASE C DELTA | PROTEINE KINASE C DELTA, PHOSPHOTRANSFERASE, ANESTHETIC BINDING SITE, METAL BINDING PROTEIN
1fpn:2 (ARG12) to (ALA34) HUMAN RHINOVIRUS SEROTYPE 2 (HRV2) | HUMAN RHINOVIRUS, POCKET FACTOR, RHINOVIRUS COAT PROTEIN, ICOSAHEDRAL VIRUS
3uhl:C (THR12) to (ASP35) CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20 IN COMPLEX WITH P2-NC SUBSTRATE ANALOG | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1rdx:B (CYS92) to (PHE117) R-STATE STRUCTURE OF THE ARG 243 TO ALA MUTANT OF PIG KIDNEY FRUCTOSE 1,6-BISPHOSPHATASE EXPRESSED IN E. COLI | HYDROLASE R243A MUTANT IN THE R-STATE, HYDROLASE
1rdz:B (CYS92) to (LEU120) T-STATE STRUCTURE OF THE ARG 243 TO ALA MUTANT OF PIG KIDNEY FRUCTOSE 1,6-BISPHOSPHATASE EXPRESSED IN E. COLI | HYDROLASE R243A MUTANT IN THE T-STATE, HYDROLASE
3uiz:A (LEU3) to (LEU43) CRYSTAL STRUCTURE OF SEFD_DSCA IN D2O | DEUTERIUM, PILIN, IMMUNOGLOBULIN, IMMUNOGLOBULIN LIKE FOLD, CHAPERONE-USHER MINOR PILIN DOMAIN, EXTRACELLULAR MEMBRANE SURFACE, STRUCTURAL PROTEIN
3uiz:C (ASP73) to (TYR96) CRYSTAL STRUCTURE OF SEFD_DSCA IN D2O | DEUTERIUM, PILIN, IMMUNOGLOBULIN, IMMUNOGLOBULIN LIKE FOLD, CHAPERONE-USHER MINOR PILIN DOMAIN, EXTRACELLULAR MEMBRANE SURFACE, STRUCTURAL PROTEIN
1rew:C (PHE35) to (ASP67) STRUCTURAL REFINEMENT OF THE COMPLEX OF BONE MORPHOGENETIC PROTEIN 2 AND ITS TYPE IA RECEPTOR | TGF-BETA FOLD; BRIA-FOLD; 3-FINGER TOXIN FOLD, HORMONE-GROWTH FACTOR- SIGNALING PROTEIN COMPLEX
2f26:A (ARG123) to (VAL159) CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 E111Q-Q112E DOUBLE MUTANT | SIALIDASE, NEURAMINIDASE, GANGLIOSIDE, DRUG DESIGN, HYDROLASE
2f3k:B (ARG8) to (GLU34) SUBSTRATE ENVELOPE AND DRUG RESISTANCE: CRYSTAL STRUCTURE OF R01 IN COMPLEX WITH WILD-TYPE HIV-1 PROTEASE | SUBSTRATE ENVELOPE, DRUG RESISTANCE, HIV PROTEASE, RO1, HYDROLASE
2f69:A (LEU169) to (PHE193) TERNARY COMPLEX OF SET7/9 BOUND TO ADOHCY AND A TAF10 PEPTIDE | SET DOMAIN, PROTEIN LYSINE METHYLTRANSFERASE, ENZYME- PEPTIDE-ADOHCY COMPLEX
1rpi:B (VAL11) to (GLU34) CRYSTAL STRUCTURES OF A MULTIDRUG-RESISTANT HIV-1 PROTEASE REVEAL AN EXPANDED ACTIVE SITE CAVITY | HIV PROTEASE, AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PORTEASE, MULTI-DRUG RESISTANCE
1rq9:B (THR12) to (GLU34) CRYSTAL STRUCTURES OF A MULTIDRUG-RESISTANT HIV-1 PROTEASE REVEAL AN EXPANDED ACTIVE SITE CAVITY | HIV PROTEASE, AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, MULTI-DRUG RESISTANCE
2fbe:B (TYR22) to (THR57) CRYSTAL STRUCTURE OF THE PRYSPRY-DOMAIN | DIMER, JELLYROLL BETA-SANDWICH FOLD, UNKNOWN FUNCTION
1g35:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR, AHA024 | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
1rw9:A (ALA726) to (LYS754) CRYSTAL STRUCTURE OF THE ARTHROBACTER AURESCENS CHONDROITIN AC LYASE | CHONDROITINASE, CHONDROITIN LYASE, LYASE
1rwf:A (ALA726) to (ARG757) CRYSTAL STRUCTURE OF ARTHROBACTER AURESCENS CHONDROITIN AC LYASE IN COMPLEX WITH CHONDROITIN TETRASACCHARIDE | CHONDROITINASE, CHONDROITIN, CHONDROITIN LYASE, LYASE
1rwg:A (ALA726) to (ARG757) CRYSTAL STRUCTURE OF ARTHROBACTER AURESCENS CHONDROITIN AC LYASE IN COMPLEX WITH CHONDROITIN TETRASACCHARIDE | CHONDROITINASE, CHONDROITIN, CHONDROITIN LYASE, LYASE
1rwh:A (ALA726) to (LYS754) CRYSTAL STRUCTURE OF ARTHROBACTER AURESCENS CHONDROITIN AC LYASE IN COMPLEX WITH CHONDROITIN TETRASACCHARIDE | CHONDROITINASE, CHONDROITIN, CHONDROITIN LYASE, LYASE
1rwq:A (THR265) to (THR307) HUMAN DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH 5-AMINOMETHYL-6-(2,4- DICHLORO-PHENYL)-2-(3,5-DIMETHOXY-PHENYL)-PYRIMIDIN-4-YLAMINE | DIPEPTIDYL PEPTIDASE IV, EXOPEPTIDASE, ADENOSINE BINDING, DRUG DESIGN, COMPLEX STRUCTURE, HYDROLASE
4z2z:A (LEU204) to (SER229) NEW CRYSTAL STRUCTURE OF YEAST DDI1 ASPARTYL PROTEASE REVEALS SUBSTRATE ENGAGEMENT MODE | PROTEASE, DDI1, HYDROLASE
4z2z:B (LEU204) to (SER229) NEW CRYSTAL STRUCTURE OF YEAST DDI1 ASPARTYL PROTEASE REVEALS SUBSTRATE ENGAGEMENT MODE | PROTEASE, DDI1, HYDROLASE
2fgu:B (VAL11) to (GLU34) X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE T80S VARIANT IN COMPLEX WITH THE INHIBITOR SAQUINAVIR USED TO EXPLORE THE ROLE OF INVARIANT THR80 IN HIV-1 PROTEASE STRUCTURE, FUNCTION, AND VIRAL INFECTIVITY. | HIV PROTEASE, DRUG RESISTANCE, ENZYME KINETICS, SEQUENCE CONSERVATION, PROTEIN STRUCTURE, HYDROLASE
2fgv:A (VAL11) to (GLU34) X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE T80N VARIANT IN COMPLEX WITH THE INHIBITOR SAQUINAVIR USED TO EXPLORE THE ROLE OF INVARIANT THR80 IN HIV-1 PROTEASE STRUCTURE, FUNCTION, AND VIRAL INFECTIVITY. | HIV PROTEASE, DRUG RESISTANCE, ENZYME KINETICS, SEQUENCE CONSERVATION, PROTEIN STRUCTURE, HYDROLASE
2fgv:B (VAL11) to (GLU34) X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE T80N VARIANT IN COMPLEX WITH THE INHIBITOR SAQUINAVIR USED TO EXPLORE THE ROLE OF INVARIANT THR80 IN HIV-1 PROTEASE STRUCTURE, FUNCTION, AND VIRAL INFECTIVITY. | HIV PROTEASE, DRUG RESISTANCE, ENZYME KINETICS, SEQUENCE CONSERVATION, PROTEIN STRUCTURE, HYDROLASE
3us8:B (GLY150) to (LEU183) CRYSTAL STRUCTURE OF AN ISOCITRATE DEHYDROGENASE FROM SINORHIZOBIUM MELILOTI 1021 | PSI-BIOLOGY, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, ISOCITRATE DEHYDROGENASE, ROSSMANN FOLD, ISOCITRATE, OXIDOREDUCTASE
2vjo:B (VAL369) to (ARG397) FORMYL-COA TRANSFERASE MUTANT VARIANT Q17A WITH ASPARTYL- COA THIOESTER INTERMEDIATES AND OXALATE | CYTOPLASM, TRANSFERASE, CLASS III COA TRANSFERASE
4z70:B (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH CA IONS | PYROPHOSPHATASE, PHOSPHATASE, HYDROLASE, INORGANIC PYROPHOSPHATE
4z70:C (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH CA IONS | PYROPHOSPHATASE, PHOSPHATASE, HYDROLASE, INORGANIC PYROPHOSPHATE
4z71:B (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MG IONS | PYROPHOSPHATASE, PHOSPHATASE, HYDROLASE, INORGANIC PYROPHOSPHATE
4z72:A (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH TWO PHOSPHATE IONS | PYROPHOSPHATASE, PHOSPHATASE, HYDROLASE, INORGANIC PYROPHOSPHATE
4z73:A (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH A PHOSPHATE ION AND AN INORGANIC PYROPHOSPHATE | INORGANIC PYROPHOSPHATASE, TUBERCULOSIS, DRUG TARGET, HYDROLASE
4z73:C (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH A PHOSPHATE ION AND AN INORGANIC PYROPHOSPHATE | INORGANIC PYROPHOSPHATASE, TUBERCULOSIS, DRUG TARGET, HYDROLASE
4z73:E (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH A PHOSPHATE ION AND AN INORGANIC PYROPHOSPHATE | INORGANIC PYROPHOSPHATASE, TUBERCULOSIS, DRUG TARGET, HYDROLASE
4z73:H (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH A PHOSPHATE ION AND AN INORGANIC PYROPHOSPHATE | INORGANIC PYROPHOSPHATASE, TUBERCULOSIS, DRUG TARGET, HYDROLASE
4z73:K (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH A PHOSPHATE ION AND AN INORGANIC PYROPHOSPHATE | INORGANIC PYROPHOSPHATASE, TUBERCULOSIS, DRUG TARGET, HYDROLASE
4z74:A (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH INORGANIC PYROPHOSPHATE | PYROPHOSPHATASE, PHOSPHATASE, HYDROLASE, INORGANIC PYROPHOSPHATE
4z74:B (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH INORGANIC PYROPHOSPHATE | PYROPHOSPHATASE, PHOSPHATASE, HYDROLASE, INORGANIC PYROPHOSPHATE
4z74:C (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH INORGANIC PYROPHOSPHATE | PYROPHOSPHATASE, PHOSPHATASE, HYDROLASE, INORGANIC PYROPHOSPHATE
4z74:D (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH INORGANIC PYROPHOSPHATE | PYROPHOSPHATASE, PHOSPHATASE, HYDROLASE, INORGANIC PYROPHOSPHATE
4z74:H (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH INORGANIC PYROPHOSPHATE | PYROPHOSPHATASE, PHOSPHATASE, HYDROLASE, INORGANIC PYROPHOSPHATE
4z74:I (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH INORGANIC PYROPHOSPHATE | PYROPHOSPHATASE, PHOSPHATASE, HYDROLASE, INORGANIC PYROPHOSPHATE
4z74:K (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH INORGANIC PYROPHOSPHATE | PYROPHOSPHATASE, PHOSPHATASE, HYDROLASE, INORGANIC PYROPHOSPHATE
4z74:L (TYR42) to (ALA73) CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH INORGANIC PYROPHOSPHATE | PYROPHOSPHATASE, PHOSPHATASE, HYDROLASE, INORGANIC PYROPHOSPHATE
2vjx:B (THR787) to (ASP812) STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES | LINEAR FREE ENERGY RELATIONSHIP, HYDROLASE, TRANSITION STATE MIMIC, MANNOSIDASE, GLYCOSIDE HYDROLASE
2fle:A (PRO9) to (GLU34) STRUCTURAL ANALYSIS OF ASYMMETRIC INHIBITOR BOUND TO THE HIV-1 PROTEASE V82A MUTANT | HIV-1 PROTEASE, INHIBITOR, RESISTANCE, INDUCED FIT, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
2frw:A (MET28) to (VAL56) SOLUTION STRUCTURE OF THE SECOND SH3 DOMAIN OF HUMAN ADAPTOR PROTEIN NCK2 | SH3, PROTEIN BINDING
4zdg:B (CYS156) to (ASP200) STRUCTURE OF THE ADENOVIRUS 14P1 KNOB DOMAIN | ADENOVIRUS 14, STRAIN P1, FIBRE KNOB, HEAD DOMAIN, VIRAL PROTEIN
4knu:A (GLU209) to (PRO238) COPPER NITRITE REDUCTASE FROM NITROSOMONAS EUROPAEA AT PH 6.5 | NITRITE REDUCTASE, OXIDOREDUCTASE
4knu:D (GLU209) to (PRO238) COPPER NITRITE REDUCTASE FROM NITROSOMONAS EUROPAEA AT PH 6.5 | NITRITE REDUCTASE, OXIDOREDUCTASE
4knu:E (GLU209) to (PRO238) COPPER NITRITE REDUCTASE FROM NITROSOMONAS EUROPAEA AT PH 6.5 | NITRITE REDUCTASE, OXIDOREDUCTASE
4knu:F (GLU209) to (PRO238) COPPER NITRITE REDUCTASE FROM NITROSOMONAS EUROPAEA AT PH 6.5 | NITRITE REDUCTASE, OXIDOREDUCTASE
1sbg:B (PRO9) to (GLU34) AN ORALLY-BIOAVAILABLE HIV-1 PROTEASE INHIBITOR CONTAINING AN IMIDAZOLE-DERIVED PEPTIDE BOND REPLACEMENT. CRYSTALLOGRAPHIC AND PHARMACOKINETIC ANALYSIS | HYDROLASE(ACID PROTEASE)
3v47:B (SER354) to (GLN382) CRYSTAL STRUCTURE OF THE N-TETMINAL FRAGMENT OF ZEBRAFISH TLR5 IN COMPLEX WITH SALMONELLA FLAGELLIN | INNATE IMMUNITY, LEUCINE-RICH REPEAT, INNATE IMMUNE RECEPTOR, IMMUNE SYSTEM
2vl4:B (THR787) to (ASP812) STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES | LINEAR FREE ENERGY RELATIONSHIP, HYDROLASE, TRANSITION STATE MIMIC, MANNOSIDASE, GLYCOSIDE HYDROLASE
1sdt:B (VAL111) to (GLU134) CRYSTAL STRUCTURES OF HIV PROTEASE V82A AND L90M MUTANTS REVEAL CHANGES IN INDINAVIR BINDING SITE. | DRUG RESISTANCE; HIV-1, HYDROLASE
1sdv:B (VAL111) to (GLU134) CRYSTAL STRUCTURES OF HIV PROTEASE V82A AND L90M MUTANTS REVEAL CHANGES IN INDINAVIR BINDING SITE. | DRUG RESISTANCE; HIV-1 PROTEASE, HYDROLASE
1se4:A (ASP127) to (ALA157) STAPHYLOCOCCAL ENTEROTOXIN B COMPLEXED WITH LACTOSE | TOXIN, SUPERANTIGEN, SEB, 3D STRUCTURE, LACTOSE, COMPLEX
4zfq:A (GLU203) to (LYS237) STRUCTURE OF M. TUBERCULOSIS (3,3) L,D-TRANSPEPTIDASE, LDTMT5. (MEROPENEN-ADDUCT FORM) | PEPTIDOGLYCAN LINKAGE, CELL WALL BIOSYNTHESIS, CARBAPENEMS, MYCOBATERIUM TUBERCULOSIS, L.D-TRANSPEPTIDASES, TRANSFERASE
2vmf:B (THR787) to (ASP812) STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES | LINEAR FREE ENERGY RELATIONSHIP, TRANSITION STATE MIMIC, MANNOSIDASE, GLYCOSIDE HYDROLASE, HYDROLASE
2vn5:A (LEU13) to (ASP53) THE CLOSTRIDIUM CELLULOLYTICUM DOCKERIN DISPLAYS A DUAL BINDING MODE FOR ITS COHESIN PARTNER | CARBOHYDRATE METABOLISM, POLYSACCHARIDE DEGRADATION, COHESIN, DOCKERIN, HYDROLASE, CELLULOSOME, GLYCOSIDASE, CELLULOSE DEGRADATION, CELL ADHESION
2vn6:A (LEU13) to (ASP53) THE CLOSTRIDIUM CELLULOLYTICUM DOCKERIN DISPLAYS A DUAL BINDING MODE FOR ITS COHESIN PARTNER | CELL ADHESION, CARBOHYDRATE METABOLISM, POLYSACCHARIDE DEGRADATION, HYDROLASE, GLYCOSIDASE, CELLULOSE DEGRADATION
1gnn:A (PRO9) to (GLU34) HIV-1 PROTEASE MUTANT WITH VAL 82 REPLACED BY ASN (V82N) COMPLEXED WITH U89360E (INHIBITOR) | ASPARTIC PROTEASE, HIV, MUTANT, INHIBITOR, U-89360E, HYDROLASE (ACID PROTEASE)
1gno:A (PRO9) to (GLU34) HIV-1 PROTEASE (WILD TYPE) COMPLEXED WITH U89360E (INHIBITOR) | ASPARTIC PROTEASE, HIV, MUTANT, INHIBITOR, U-89360E, HYDROLASE (ACID PROTEASE)
3v6o:B (ASN433) to (SER470) LEPTIN RECEPTOR-ANTIBODY COMPLEX | RECEPTOR-ANTIBODY COMPLEX, CYTOKINE RECEPTOR, ANTIBODY FAB FRAGMENT, IMMUNOGLOBULIN FOLD, LEPTIN RECEPTOR-ANTIBODY COMPLEX, IMMUNE SYSTEM
2vo5:B (THR787) to (ASP812) STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES | GLYCOSIDE, HYDROLASE, MANNOSIDASE, TRANSITION STATE MIMIC, LINEAR FREE ENERGY RELATIONSHIP
1goz:B (LYS2128) to (ALA2157) STRUCTURAL BASIS FOR THE ALTERED T-CELL RECEPTOR BINDING SPECIFICTY IN A SUPERANTIGENIC STAPHYLOCOCCUS AUREUS ENTEROTOXIN-B MUTANT | ENTEROTOXIN, STAPHYLOCOCCAL ENTEROTOXINS, SEB, ENTEROTOXIN B
2vot:A (THR787) to (ASP812) STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES | LINEAR FREE ENERGY RELATIONSHIP, HYDROLASE, TRANSITION STATE MIMIC, MANNOSIDASE, GLYCOSIDE HYDROLASE
2vot:B (THR787) to (ASP812) STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES | LINEAR FREE ENERGY RELATIONSHIP, HYDROLASE, TRANSITION STATE MIMIC, MANNOSIDASE, GLYCOSIDE HYDROLASE
4kro:A (ASN274) to (LYS304) NANOBODY/VHH DOMAIN EGA1 IN COMPLEX WITH THE EXTRACELLULAR REGION OF EGFR | CELL SURFACE RECEPTOR, GLYCOPROTEIN, NANOBODY, VHH DOMAIN, CAMELID VH DOMAIN, ANTIBODY, ANTIGEN, ANTIBODY COMPLEX, TRANSFERASE-IMMUNE SYSTEM COMPLEX
2g2n:D (GLY33) to (VAL65) CRYSTAL STRUCTURE OF E.COLI TRANSTHYRETIN-RELATED PROTEIN WITH BOUND ZN | TRANSTHYRETIN, TRANSTHYRETIN-RELATED PROTEIN, UNKNOWN FUNCTION
3i3b:C (PHE626) to (ALA657) E.COLI (LACZ) BETA-GALACTOSIDASE (M542A) IN COMPLEX WITH D- GALACTOPYRANOSYL-1-ON | BETA-GALACTOSIDASE, TIM BARREL (ALPHA/BETA BARREL), JELLY-ROLL BARREL, IMMUNOGLOBULIN BETA SUPERSANDWHICH, GLYCOSIDASE, HYDROLASE
3i3b:D (PHE626) to (ALA657) E.COLI (LACZ) BETA-GALACTOSIDASE (M542A) IN COMPLEX WITH D- GALACTOPYRANOSYL-1-ON | BETA-GALACTOSIDASE, TIM BARREL (ALPHA/BETA BARREL), JELLY-ROLL BARREL, IMMUNOGLOBULIN BETA SUPERSANDWHICH, GLYCOSIDASE, HYDROLASE
2vqt:B (THR787) to (ASP812) STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES | LINEAR FREE ENERGY RELATIONSHIP, TRANSITION STATE MIMIC, HYDROLASE, MANNOSIDASE, GLYCOSIDE HYDROLASE
3i3d:C (PHE626) to (VAL656) E. COLI (LACZ) BETA-GALACTOSIDASE (M542A) IN COMPLEX WITH IPTG | BETA-GALACTOSIDASE, TIM BARREL (ALPHA/BETA BARREL), JELLY-ROLL BARREL, IMMUNOGLOBULIN BETA SUPERSANDWHICH, GLYCOSIDASE, HYDROLASE
2vt5:E (CYS92) to (LEU120) FRUCTOSE-1,6-BISPHOSPHATASE(D-FRUCTOSE-1,6-BISPHOSPHATE -1-PHOSPHOHYDROLASE) (E.C.3.1.3.11) COMPLEXED WITH A DUAL BINDING AMP SITE INHIBITOR | HYDROLASE (PHOSPHORIC MONOESTER), DISEASE MUTATION, ALLOSTERIC ENZYME, ZINC, HYDROLASE, POLYMORPHISM, GLUCONEOGENESIS, CARBOHYDRATE METABOLISM
1so7:A (ARG123) to (VAL159) MALTOSE-INDUCED STRUCTURE OF THE HUMAN CYTOLSOLIC SIALIDASE NEU2 | SIALIDASE, NEURAMINIDASE, GANGLIOSIDE, SUGAR-INDUCED FORM, HYDROLASE
4zip:B (VAL11) to (GLU34) HIV-1 WILD TYPE PROTEASE WITH GRL-0648A (A ISOPHTHALAMIDE-DERIVED P2- LIGAND) | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1sp5:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH A PRODUCT OF AUTOPROTEOLYSIS | PRODUCT, PEPTIDE, AUTOPROTEOLYSIS, SELF-DIGESTION, AUTODIGESTION, ASPARTIC PROTEASE, HIV, PROTEASE, COMPLEX(ASPARTIC PROTEASE/PEPTIDE), HYDROLASE
2vtx:B (LEU17) to (LEU47) ACTIVATION OF NUCLEOPLASMIN, AN OLIGOMERIC HISTONE CHAPERONE, CHALLENGES ITS STABILITY | NUCLEOPLASMIN, PHOSPHORYLATION, PROTEIN STABILITY, OLIGOMERIC PROTEIN, NUCLEAR PROTEIN
2vtx:H (LEU17) to (LEU47) ACTIVATION OF NUCLEOPLASMIN, AN OLIGOMERIC HISTONE CHAPERONE, CHALLENGES ITS STABILITY | NUCLEOPLASMIN, PHOSPHORYLATION, PROTEIN STABILITY, OLIGOMERIC PROTEIN, NUCLEAR PROTEIN
1spi:B (GLY102) to (LEU130) CRYSTAL STRUCTURE OF SPINACH CHLOROPLAST FRUCTOSE-1,6- BISPHOSPHATASE AT 2.8 ANGSTROMS RESOLUTION | HYDROLASE (PHOSPHORIC MONOESTER)
4ziq:A (LYS1444) to (ASN1465) CRYSTAL STRUCTURE OF TRYPSIN ACTIVATED ALPHA-2-MACROGLOBULIN FROM ESCHERICHIA COLI. | BACTERIAL PAN-PROTEINASE INHIBITOR, MEMBRANE PROTEIN
3vd4:C (PHE626) to (ALA657) E. COLI (LACZ) BETA-GALACTOSIDASE (N460D) IN COMPLEX WITH IPTG | TRANSITION STATE STABILIZATION, SUBSTRATE BINDING, 2-STAGE BINDING, TIM BARREL (ALPHA/BETA BARREL), JELLY-ROLL BARREL, IMMUNOGLOBULIN, BETA SUPERSANDWICH, GLYCOSIDASE, HYDROLASE
2vvf:A (LEU144) to (ALA179) CRYSTAL STRUCTURE OF THE MAJOR CAPSID PROTEIN P2 FROM BACTERIOPHAGE PM2 | DOUBLE JELLY-ROLL VIRAL CAPSID, VIRAL PROTEIN
2vvf:B (LEU144) to (ALA179) CRYSTAL STRUCTURE OF THE MAJOR CAPSID PROTEIN P2 FROM BACTERIOPHAGE PM2 | DOUBLE JELLY-ROLL VIRAL CAPSID, VIRAL PROTEIN
2vvf:C (LEU144) to (ALA179) CRYSTAL STRUCTURE OF THE MAJOR CAPSID PROTEIN P2 FROM BACTERIOPHAGE PM2 | DOUBLE JELLY-ROLL VIRAL CAPSID, VIRAL PROTEIN
2vvf:D (LEU144) to (ALA179) CRYSTAL STRUCTURE OF THE MAJOR CAPSID PROTEIN P2 FROM BACTERIOPHAGE PM2 | DOUBLE JELLY-ROLL VIRAL CAPSID, VIRAL PROTEIN
2vvf:E (LEU144) to (ALA179) CRYSTAL STRUCTURE OF THE MAJOR CAPSID PROTEIN P2 FROM BACTERIOPHAGE PM2 | DOUBLE JELLY-ROLL VIRAL CAPSID, VIRAL PROTEIN
2vvf:F (LEU144) to (ALA179) CRYSTAL STRUCTURE OF THE MAJOR CAPSID PROTEIN P2 FROM BACTERIOPHAGE PM2 | DOUBLE JELLY-ROLL VIRAL CAPSID, VIRAL PROTEIN
4kx9:A (PRO582) to (ASN607) CRYSTAL STRUCTURE OF HUMAN AMINOPEPTIDASE A COMPLEXED WITH ARGININE | ZINC-AMINOPEPTIDASE, HYDROLASE
3i6o:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE WITH MACROCYCLIC INHIBITOR GRL-0216A | HIV-1, WILD TYPE PROTEASE, PROTEASE INHIBITOR, MACROCYCLIC LIGAND, AIDS, ASPARTYL PROTEASE, HYDROLASE
4kxc:A (PRO582) to (ASN607) CRYSTAL STRUCTURE OF HUMAN AMINOPEPTIDASE A COMPLEXED WITH GLUTAMATE | ZINC-AMINOPEPTIDASE, HYDROLASE
1stm:A (ALA17) to (VAL57) SATELLITE PANICUM MOSAIC VIRUS | VIRUS, ICOSAHEDRAL VIRUS
1stm:B (ALA17) to (VAL57) SATELLITE PANICUM MOSAIC VIRUS | VIRUS, ICOSAHEDRAL VIRUS
1stm:C (ALA17) to (VAL57) SATELLITE PANICUM MOSAIC VIRUS | VIRUS, ICOSAHEDRAL VIRUS
1stm:D (ALA17) to (VAL57) SATELLITE PANICUM MOSAIC VIRUS | VIRUS, ICOSAHEDRAL VIRUS
1stm:E (ALA17) to (VAL57) SATELLITE PANICUM MOSAIC VIRUS | VIRUS, ICOSAHEDRAL VIRUS
2vw1:A (TYR458) to (GLY493) CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE | HYDROLASE, SIALIDASE, NEURAMINIDASE, VIRULENCE FACTOR, DRUG DESIGN
3i7e:A (VAL11) to (GLU34) CO-CRYSTAL STRUCTURE OF HIV-1 PROTEASE BOUND TO A MUTANT RESISTANT INHIBITOR UIC-98038 | AIDS, HIV, HIV PRTEASE, HIV-PROTEASE INHIBITOR, DRUG DESIGN, ASPARTIC PROTEASE, ACID PROTEASE, STRUCTURE BASED DRUG DESIGN, ASPARTYL PROTEASE, HYDROLASE, PROTEASE
3vd9:C (PHE626) to (VAL656) E. COLI (LACZ) BETA-GALACTOSIDASE (N460S) IN COMPLEX WITH IPTG | TRANSITION STATE STABILIZATION, SUBSTRATE BINDING, 2-STAGE BINDING, TIM BARREL (ALPHA/BETA BARREL), JELLY-ROLL BARREL, IMMUNOGLOBULIN, BETA SUPERSANDWICH, GLYCOSIDASE, HYDROLASE
1sva:4 (SER43) to (VAL119) SIMIAN VIRUS 40 | VIRUS COAT PROTEIN, ICOSAHEDRAL VIRUS
2gfs:A (THR7) to (PRO29) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH RO3201195 | P38; MAP KINASE; SERINE/THREONINE KINASE, SIGNALING PROTEIN, TRANSFERASE
1sxv:A (TYR42) to (ALA73) 1.3A CRYSTAL STRUCTURE OF RV3628, MYCOBACTERIUM TUBERCULOSIS INORGANIC PYROPHOSPHATASE (PPASE) AT PH5.0 | MYCOBACTERIUM TUBERCULOSIS, STRUCTURAL GENOMICS, INORGANIC PYROPHOSPHATASE, PPASE,, HYDROLASE
3vfa:B (PRO9) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT V82A WITH NOVEL P1'-LIGANDS GRL-02031 | PROTEASE INHIBITOR,P1'-LIGAND, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1h0j:C (LEU1) to (MET26) STRUCTURAL BASIS OF THE MEMBRANE-INDUCED CARDIOTOXIN A3 OLIGOMERIZATION | CARDIOTOXIN, SODIUM DODECYL SULFATE, VENOM, CYTOTOXIN
4zmu:A (ARG111) to (LEU141) DCSBIS, A DIGUANYLATE CYCLASE FROM PSEUDOMONAS AERUGINOSA | CELL MOTILITIES, DIGUANYL CYCLASE, GGDEF DOMAIN, GAF DOMAIN, LYASE
2gn4:A (LEU275) to (LYS301) CRYSTAL STRUCTURE OF UDP-GLCNAC INVERTING 4,6-DEHYDRATASE IN COMPLEX WITH NADPH AND UDP-GLCNAC | ROSSMANN FOLD, TYK TRIAD, SDR, ENZYME, DEHYDRATASE, UDP- GLCNAC, NADP, NADPH, LYASE
2gn4:B (LEU275) to (LYS301) CRYSTAL STRUCTURE OF UDP-GLCNAC INVERTING 4,6-DEHYDRATASE IN COMPLEX WITH NADPH AND UDP-GLCNAC | ROSSMANN FOLD, TYK TRIAD, SDR, ENZYME, DEHYDRATASE, UDP- GLCNAC, NADP, NADPH, LYASE
2gn8:A (LEU275) to (LYS301) CRYSTAL STRUCTURE OF UDP-GLCNAC INVERTING 4,6-DEHYDRATASE IN COMPLEX WITH NADP AND UDP | ROSSMANN FOLD, TYK TRIAD, SDR, ENZYME, DEHYDRATASE, UDP-GLCNAC, NADP, LYASE
2w0c:A (LEU144) to (ALA179) X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2 | VIRUS, MEMBER OF PRD1-ADENO VIRAL LINEAGE, MEMBRANE-CONTAINING BACTERIOPHAGE, VIRUS VIRION, MEMBRANE, TRANSMEMBRANE, CAPSID PROTEIN
2w0c:B (LEU144) to (ALA179) X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2 | VIRUS, MEMBER OF PRD1-ADENO VIRAL LINEAGE, MEMBRANE-CONTAINING BACTERIOPHAGE, VIRUS VIRION, MEMBRANE, TRANSMEMBRANE, CAPSID PROTEIN
2w0c:C (LEU144) to (ALA179) X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2 | VIRUS, MEMBER OF PRD1-ADENO VIRAL LINEAGE, MEMBRANE-CONTAINING BACTERIOPHAGE, VIRUS VIRION, MEMBRANE, TRANSMEMBRANE, CAPSID PROTEIN
2w0c:D (LEU144) to (ALA179) X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2 | VIRUS, MEMBER OF PRD1-ADENO VIRAL LINEAGE, MEMBRANE-CONTAINING BACTERIOPHAGE, VIRUS VIRION, MEMBRANE, TRANSMEMBRANE, CAPSID PROTEIN
2w0c:E (LEU144) to (ALA179) X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2 | VIRUS, MEMBER OF PRD1-ADENO VIRAL LINEAGE, MEMBRANE-CONTAINING BACTERIOPHAGE, VIRUS VIRION, MEMBRANE, TRANSMEMBRANE, CAPSID PROTEIN
2w0c:F (LEU144) to (ALA179) X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2 | VIRUS, MEMBER OF PRD1-ADENO VIRAL LINEAGE, MEMBRANE-CONTAINING BACTERIOPHAGE, VIRUS VIRION, MEMBRANE, TRANSMEMBRANE, CAPSID PROTEIN
2w0c:G (LEU144) to (ALA179) X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2 | VIRUS, MEMBER OF PRD1-ADENO VIRAL LINEAGE, MEMBRANE-CONTAINING BACTERIOPHAGE, VIRUS VIRION, MEMBRANE, TRANSMEMBRANE, CAPSID PROTEIN
2w0c:H (LEU144) to (ALA179) X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2 | VIRUS, MEMBER OF PRD1-ADENO VIRAL LINEAGE, MEMBRANE-CONTAINING BACTERIOPHAGE, VIRUS VIRION, MEMBRANE, TRANSMEMBRANE, CAPSID PROTEIN
2w0c:I (LEU144) to (ALA179) X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2 | VIRUS, MEMBER OF PRD1-ADENO VIRAL LINEAGE, MEMBRANE-CONTAINING BACTERIOPHAGE, VIRUS VIRION, MEMBRANE, TRANSMEMBRANE, CAPSID PROTEIN
2w0c:J (LEU144) to (ALA179) X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2 | VIRUS, MEMBER OF PRD1-ADENO VIRAL LINEAGE, MEMBRANE-CONTAINING BACTERIOPHAGE, VIRUS VIRION, MEMBRANE, TRANSMEMBRANE, CAPSID PROTEIN
2goo:B (PHE35) to (ASP67) TERNARY COMPLEX OF BMP-2 BOUND TO BMPR-IA-ECD AND ACTRII-ECD | TGF-BETA, BMP-2, BMPR-IA, ACTRII, ALK-3,, TRANSFERASE
2w1s:A (GLU898) to (GLU930) UNIQUE LIGAND BINDING SPECIFICITY OF A FAMILY 32 CARBOHYDRATE-BINDING MODULE FROM THE MU TOXIN PRODUCED BY CLOSTRIDIUM PERFRINGENS | HEXOSAMINIDASE, CLOSTRIDIUM PERFRINGENS, FAMILY 32 CARBOHYDRATE BINDING MODULE, TOXIN, SECRETED, VIRULENCE, HYDROLASE, GLYCOSIDASE, FAMILY 84 GLYCOSIDE HYDROLASE
1t7i:B (VAL11) to (GLU34) THE STRUCTURAL AND THERMODYNAMIC BASIS FOR THE BINDING OF TMC114, A NEXT-GENERATION HIV-1 PROTEASE INHIBITOR. | HIV-1 PROTEASE, DRUG RESITANCE, THERMODYNAMICS, SUBSTRATE ENVELOPE, HYDROLASE
1t7k:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH ARYLSULFONAMIDE AZACYCLIC UREA | HIV PROTEASE, ARYLSULFONAMIDE AZACYCLIC UREA, HYDROLASE
2gq8:A (GLN7) to (SER28) STRUCTURE OF SYE1, AN OYE HOMOLOGUE FROM S. ONDEIDENSIS, IN COMPLEX WITH P-HYDROXYACETOPHENONE | OLD YELLOW ENZYME, FLAVOENZYME, FMN, PHENOLIC LIGANDS, OXIDOREDUCTASE
2gqa:A (GLN7) to (SER28) STRUCTURE OF NADH-REDUCED SYE1, AN OYE HOMOLOGUE FROM S. ONEIDENSIS | OLD YELLOW ENZYME, FLAVOENZYME, FMN, REDUCTION BY NADH, OXIDOREDUCTASE
4zpn:B (TYR50) to (GLN83) CRYSTAL STRUCTURE OF PROTOCADHERIN GAMMA C5 EC1-3 WITH EXTENDED N- TERMINUS | CELL ADHESION
1hb5:C (SER255) to (PHE291) QUASI-ATOMIC RESOLUTION MODEL OF BACTERIOPHAGE PRD1 P3-SHELL, OBTAINED BY COMBINED CRYO-EM AND X-RAY CRYSTALLOGRAPHY. | VIRUS, VIRUS/VIRAL PROTEIN, TECTIVIRIDAE, BACTERIOPHAGE PRD1, CRYO- EM, IMAGE RECONSTRUCTION, ICOSAHEDRAL VIRUS
1hb5:F (SER255) to (PHE291) QUASI-ATOMIC RESOLUTION MODEL OF BACTERIOPHAGE PRD1 P3-SHELL, OBTAINED BY COMBINED CRYO-EM AND X-RAY CRYSTALLOGRAPHY. | VIRUS, VIRUS/VIRAL PROTEIN, TECTIVIRIDAE, BACTERIOPHAGE PRD1, CRYO- EM, IMAGE RECONSTRUCTION, ICOSAHEDRAL VIRUS
1hb5:I (SER255) to (PHE291) QUASI-ATOMIC RESOLUTION MODEL OF BACTERIOPHAGE PRD1 P3-SHELL, OBTAINED BY COMBINED CRYO-EM AND X-RAY CRYSTALLOGRAPHY. | VIRUS, VIRUS/VIRAL PROTEIN, TECTIVIRIDAE, BACTERIOPHAGE PRD1, CRYO- EM, IMAGE RECONSTRUCTION, ICOSAHEDRAL VIRUS
1tcx:A (ARG8) to (GLU34) HIV TRIPLE MUTANT PROTEASE COMPLEXED WITH INHIBITOR SB203386 | AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE, RNA-DIRECTED DNA POLYMERASE, ACID PROTEASE, HYDROLASE (ACID PROTEASE)
1tcx:B (ARG8) to (GLU34) HIV TRIPLE MUTANT PROTEASE COMPLEXED WITH INHIBITOR SB203386 | AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE, RNA-DIRECTED DNA POLYMERASE, ACID PROTEASE, HYDROLASE (ACID PROTEASE)
4ldt:A (GLY226) to (PRO265) THE STRUCTURE OF H/CEOTUB1-UBIQUITIN ALDEHYDE-UBCH5B~UB | ISOPEPTIDASE, UBIQUITIN-CONJUGATING, POST-TRANSLATIONAL MODIFICATION, UBIQUITIN, UBIQUITIN-ALDEHYDE, HYDROLASE REGULATOR
1hb9:C (SER255) to (PHE291) QUASI-ATOMIC RESOLUTION MODEL OF BACTERIOPHAGE PRD1 WILD TYPE VIRION, OBTAINED BY COMBINED CRYO-EM AND X-RAY CRYSTALLOGRAPHY. | VIRUS, VIRUS/VIRAL PROTEIN, TECTIVIRIDAE, BACTERIOPHAGE PRD1, CRYO- EM, IMAGE RECONSTRUCTION, ICOSAHEDRAL VIRUS
1hb9:F (SER255) to (PHE291) QUASI-ATOMIC RESOLUTION MODEL OF BACTERIOPHAGE PRD1 WILD TYPE VIRION, OBTAINED BY COMBINED CRYO-EM AND X-RAY CRYSTALLOGRAPHY. | VIRUS, VIRUS/VIRAL PROTEIN, TECTIVIRIDAE, BACTERIOPHAGE PRD1, CRYO- EM, IMAGE RECONSTRUCTION, ICOSAHEDRAL VIRUS
1hb9:I (SER255) to (PHE291) QUASI-ATOMIC RESOLUTION MODEL OF BACTERIOPHAGE PRD1 WILD TYPE VIRION, OBTAINED BY COMBINED CRYO-EM AND X-RAY CRYSTALLOGRAPHY. | VIRUS, VIRUS/VIRAL PROTEIN, TECTIVIRIDAE, BACTERIOPHAGE PRD1, CRYO- EM, IMAGE RECONSTRUCTION, ICOSAHEDRAL VIRUS
1hb9:L (SER255) to (PHE291) QUASI-ATOMIC RESOLUTION MODEL OF BACTERIOPHAGE PRD1 WILD TYPE VIRION, OBTAINED BY COMBINED CRYO-EM AND X-RAY CRYSTALLOGRAPHY. | VIRUS, VIRUS/VIRAL PROTEIN, TECTIVIRIDAE, BACTERIOPHAGE PRD1, CRYO- EM, IMAGE RECONSTRUCTION, ICOSAHEDRAL VIRUS
4lej:A (PRO380) to (ALA409) CRYSTAL STRUCTURE OF THE KOREAN PINE (PINUS KORAIENSIS) VICILIN | SEED STORAGE PROTEIN, ALLERGEN, CUPIN, SEED STORAGE, PLANT PROTEIN
4zu7:A (TRP96) to (ASN124) X-RAY STRUCTURE IF THE QDTA 3,4-KETOISOMERASE FROM THERMOANAEROBACTERIUM THERMOSACCHAROLYTICUM, DOUBLE MUTANT Y17R/R97H, IN COMPLEX WITH TDP | CUPIN ISOMERASE 3-4-KETOISOMERASE, ISOMERASE
1hef:E (ARG8) to (GLU34) THE CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF HYDROXYETHYLENE- BASED INHIBITORS BOUND TO HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE SHOW THAT THE INHIBITORS ARE PRESENT IN TWO DISTINCT ORIENTATIONS | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1hes:A (PHE287) to (LYS319) MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH P-SELECTIN INTERNALIZATION PEPTIDE SHLGTYGVFTNAA | ENDOCYTOSIS/EXOCYTOSIS, ENDOCYTOSIS, ADAPTOR, PEPTIDE COMPLEX, PEPTIDE BINDING PROTE
4li1:B (SER193) to (HIS222) CRYSTAL STRUCTURES OF LGR4 AND ITS COMPLEX WITH R-SPONDIN1 | LRR, HORMONE RECEPTOR
1hih:A (ARG8) to (GLU34) COMPARATIVE ANALYSIS OF THE X-RAY STRUCTURES OF HIV-1 AND HIV-2 PROTEASES IN COMPLEX WITH CGP 53820, A NOVEL PSEUDOSYMMETRIC INHIBITOR | ASPARTATE PROTEASE, INHIBITED, HIV, HYDROLASE (ASPARTIC PROTEINASE)
3isr:D (TYR-5) to (ASP35) THE CRYSTAL STRUCTURE OF A PUTATIVE CYSTEINE PROTEASE FROM CYTOPHAGA HUTCHINSONII TO 1.9A | TRANSGLUTAMINASE, CYSTEINE, PROTEASE, CYTOPHAGA, HUTCHINSONII, PSI, MCSG, STRUCTURAL GENOMICS, MIDWEST CENTER FOR STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, HYDROLASE
1tme:2 (VAL14) to (GLY35) THREE-DIMENSIONAL STRUCTURE OF THEILER VIRUS | VIRUS, ICOSAHEDRAL VIRUS
1tmf:2 (VAL14) to (GLY35) THREE-DIMENSIONAL STRUCTURE OF THEILER MURINE ENCEPHALOMYELITIS VIRUS (BEAN STRAIN) | COAT PROTEIN, ICOSAHEDRAL VIRUS
3isy:A (GLY40) to (GLU74) CRYSTAL STRUCTURE OF AN INTRACELLULAR PROTEINASE INHIBITOR (IPI, BSU11130) FROM BACILLUS SUBTILIS AT 2.61 A RESOLUTION | INTRACELLULAR PROTEINASE INHIBITOR BSUPI, BETA SANDWICH, GREEK KEY, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, PROTEIN BINDING
2wbd:E (CYS92) to (PHE117) FRUCTOSE-1,6-BISPHOSPHATASE(D-FRUCTOSE-1,6-BISPHOSPHATE-1- PHOSPHOHYDROLASE) (E.C.3.1.3.11) COMPLEXED WITH AN AMP SITE INHIBITOR | PHOSPHORIC MONOESTER, ALLOSTERIC ENZYME, CARBOHYDRATE METABOLISM, GLUCONEOGENESIS, HYDROLASE
2h8x:A (GLU6) to (TYR27) XENOBIOTIC REDUCTASE A-OXIDIZED | BETA-ALPHA BARREL, OXIDOREDUCTASE
2h8u:B (ARG1) to (GLU29) BUCAIN, A CARDIOTOXIN FROM THE MALAYAN KRAIT BUNGARUS CANDIDUS | BUCAIN, CARDIOTOXIN
2wbk:B (SER788) to (ASP812) STRUCTURE OF THE MICHAELIS COMPLEX OF BETA-MANNOSIDASE, MAN2A, PROVIDES INSIGHT INTO THE CONFORMATIONAL ITINERARY OF MANNOSIDE HYDROLYSIS | GLYCOSIDE HYDROLASE, CONFORMATIONAL ITINERARY, HYDROLASE, MANNOSIDASE, BETA-MANNOSIDE, MICHAELIS COMPLEX
3itz:A (THR7) to (PRO29) CRYSTAL STRUCTURE OF P38A MITOGEN-ACTIVATED PROTEIN KINASE IN COMPLEX WITH A PYRAZOLOPYRIDAZINE INHIBITOR | SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM
2hb3:B (ARG8) to (GLU34) WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH POTENT INHIBITOR GRL06579 | ACTIVE-SITE CAVITY PROTEASE INHIBITOR CATALYTIC ASPARTIC ACID, HYDROLASE
2hc0:A (VAL1011) to (GLU1034) STRUCTURE OF HIV PROTEASE 6X MUTANT IN COMPLEX WITH AB-2. | HIV, PROTEASE, MUTANT, ASPARTYL, HYDROLASE
2hc0:B (VAL2111) to (GLU2134) STRUCTURE OF HIV PROTEASE 6X MUTANT IN COMPLEX WITH AB-2. | HIV, PROTEASE, MUTANT, ASPARTYL, HYDROLASE
2wdb:D (SER892) to (GLU930) A FAMILY 32 CARBOHYDRATE-BINDING MODULE, FROM THE MU TOXIN PRODUCED BY CLOSTRIDIUM PERFRINGENS, IN COMPLEX WITH BETA- D-GLCNAC-BETA(1,2)MANNOSE | FAMILY 32 CARBOHYDRATE BINDING MODULE, FAMILY 84 GLYCOSIDE HYDROLASE, GLYCOSIDASE, HEXOSAMINIDASE, CLOSTRIDIUM PERFRINGENS, CBM, TOXIN, SECRETED, VIRULENCE, HYDROLASE
1hos:A (PRO9) to (GLU34) INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE BY A C2- SYMMETRIC PHOSPHINATE SYNTHESIS AND CRYSTALLOGRAPHIC ANALYSIS | HYDROLASE(ACID PROTEINASE)
1hps:A (ARG8) to (GLU34) RATIONAL DESIGN, SYNTHESIS AND CRYSTALLOGRAPHIC ANALYSIS OF A HYDROXYETHYLENE-BASED HIV-1 PROTEASE INHIBITOR CONTAINING A HETEROCYCLIC P1'-P2' AMIDE BOND ISOSTERE | HYDROLASE(ACID PROTEINASE)
1hps:B (VAL11) to (GLU34) RATIONAL DESIGN, SYNTHESIS AND CRYSTALLOGRAPHIC ANALYSIS OF A HYDROXYETHYLENE-BASED HIV-1 PROTEASE INHIBITOR CONTAINING A HETEROCYCLIC P1'-P2' AMIDE BOND ISOSTERE | HYDROLASE(ACID PROTEINASE)
4lk6:J (ALA64) to (ASN88) CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN LECA COMPLEXED WITH CHLOROPHENOL RED-B-D-GALACTOPYRANOSIDE AT 2.86 A RESOLUTION | LECTIN FOLD, SUGAR BINDING PROTEIN, GALACTOSE
3von:A (SER230) to (PRO263) CRYSTALSTRUCTURE OF THE UBIQUITIN PROTEASE | UBIQUITIN PROTEASE, HYDROLASE-LIGASE COMPLEX
3von:V (SER230) to (PRO263) CRYSTALSTRUCTURE OF THE UBIQUITIN PROTEASE | UBIQUITIN PROTEASE, HYDROLASE-LIGASE COMPLEX
3von:c (VAL229) to (PRO263) CRYSTALSTRUCTURE OF THE UBIQUITIN PROTEASE | UBIQUITIN PROTEASE, HYDROLASE-LIGASE COMPLEX
1tsu:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF DECAMER NCP1 SUBSTRATE PEPTIDE IN COMPLEX WITH WILD-TYPE D25N HIV-1 PROTEASE VARIANT | CO-EVOLUTION, NUCLEOCAPDIS, SUBSTRATE RECOGNITION, HIV-1 PROTEASE, VIRAL PROTEIN/HYDROLASE COMPLEX
1hsg:B (PRO9) to (GLU34) CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L- 735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES | HYDROLASE (ACID PROTEINASE)
1hte:B (ARG8) to (GLU34) X-RAY CRYSTALLOGRAPHIC STUDIES OF A SERIES OF PENICILLIN- DERIVED ASYMMETRIC INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEINASE)
1htf:B (ARG8) to (GLU34) X-RAY CRYSTALLOGRAPHIC STUDIES OF A SERIES OF PENICILLIN- DERIVED ASYMMETRIC INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEINASE)
1htg:A (VAL11) to (GLU34) X-RAY CRYSTALLOGRAPHIC STUDIES OF A SERIES OF PENICILLIN- DERIVED ASYMMETRIC INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEINASE)
1htg:B (VAL11) to (GLU34) X-RAY CRYSTALLOGRAPHIC STUDIES OF A SERIES OF PENICILLIN- DERIVED ASYMMETRIC INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEINASE)
2wii:B (MET916) to (ALA966) COMPLEMENT C3B IN COMPLEX WITH FACTOR H DOMAINS 1-4 | IMMUNE SYSTEM, SUSHI, SECRETED, POLYMORPHISM, GLYCOPROTEIN, COMPLEMENT SYSTEM, COMPLEMENT PATHWAY, IMMUNE RESPONSE, INNATE IMMUNITY, DISEASE MUTATION, INFLAMMATORY RESPONSE, COMPLEMENT ALTERNATE PATHWAY, CLEAVAGE ON PAIR OF BASIC RESIDUES, AGE-RELATED MACULAR DEGENERATION, REGULATOR OF COMPLEMENT ACTIVATION, ALTERNATIVE PATHWAY, ALTERNATIVE SPLICING, PHOSPHOPROTEIN, DISULFIDE BOND, THIOESTER BOND
4lnn:K (LYS19) to (ASP53) B. SUBTILIS GLUTAMINE SYNTHETASE STRUCTURES REVEAL LARGE ACTIVE SITE CONFORMATIONAL CHANGES AND BASIS FOR ISOENZYME SPECIFIC REGULATION: STRUCTURE OF APO FORM OF GS | GLUTAMINE SYNTHETASE, ENZYME, DODECAMER, ALPHA/BETA, LIGASE
1hx6:C (SER255) to (PHE291) P3, THE MAJOR COAT PROTEIN OF THE LIPID-CONTAINING BACTERIOPHAGE PRD1. | BACTERIOPHAGE PRD1, COAT PROTEIN, JELLY ROLL, VIRAL BETA BARREL, VIRAL PROTEIN
1tye:E (LEU264) to (VAL295) STRUCTURAL BASIS FOR ALLOSTERY IN INTEGRINS AND BINDING OF LIGAND- MIMETIC THERAPEUTICS TO THE PLATELET RECEPTOR FOR FIBRINOGEN | CRYSTAL STRUCTURE; PLATELET INTEGRIN ALPHAIIBBETA3; FIBRINOGEN BINDING; ALLOSTERY; THERAPEUTIC ANTAGONISM, CELL ADHESION
3iyp:C (VAL12) to (GLY33) THE INTERACTION OF DECAY-ACCELERATING FACTOR WITH ECHOVIRUS 7 | VIRUS, RECEPTOR, COMPLEX, ECHOVIRUS, DAF, ICOSAHEDRAL VIRUS
2wkz:B (VAL111) to (GLU134) HIV-1 PROTEASE INHIBITORS CONTAINING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMIC WITH IMPROVED CELL-BASED ANTIVIRAL ACTIVITY | TRANSITION-STATE MIMIC, INHIBITOR, HYDROLASE
3vv0:A (LEU169) to (PHE193) CRYSTAL STRUCTURE OF HISTONE METHYLTRANSFERASE SET7/9 IN COMPLEX WITH DAAM-3 | SET DOMAIN, TRANSFERASE, ADENOSYLMETHIONINE BINDING, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
1i02:A (LEU1) to (PHE25) NMR STRUCTURE OF CTX A3 AT NEUTRAL PH (20 STRUCTURES) | CARDIOTOXIN, CTX, CYTOTOXIN, HEMOLYSIS, MEMBRANE BINDING PROTEIN, GAG BINDING PROTEIN, BOUND WATER, THREE-FINGER TYPE
1i31:A (PRO286) to (LYS319) MU2 ADAPTIN SUBUNIT (AP50) OF AP2 CLATHRIN ADAPTOR, COMPLEXED WITH EGFR INTERNALIZATION PEPTIDE FYRALM AT 2.5 A RESOLUTION | BETA-SANDWICH, PEPTIDE-BINDING SITE, PROTEIN-PEPTIDE COMPLEX, CLATHRIN ADAPTOR, ENDOCYTOSIS/EXOCYTOSIS COMPLEX
2hs2:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF M46L MUTANT OF HIV-1 PROTEASE COMPLEXED WITH TMC114 (DARUNAVIR) | ASPARTIC PROTEASE ACTIVE SITE SURFACE BINDING SITE, HYDROLASE
4lub:A (LYS76) to (HIS189) X-RAY STRUCTURE OF PREPHENATE DEHYDRATASE FROM STREPTOCOCCUS MUTANS | DEHYDRATASE, DEHYDRATION, LYASE
3w37:A (LYS845) to (GLU907) SUGAR BEET ALPHA-GLUCOSIDASE WITH ACARBOSE | ALPHA-GLUCOSIDASE, GLYCOSIDE HYDROLASE FAMILY 31, (BETA/ALPHA)8- BARREL, ACARBOSE, HYDROLASE, CARBOHYDRATE
3w38:A (LYS845) to (GLU907) SUGAR BEET ALPHA-GLUCOSIDASE | ALPHA-GLUCOSIDASE, GLYCOSIDE HYDROLASE FAMILY 31, (BETA/ALPHA)8- BARREL, HYDROLASE, CARBOHYDRATE
1u8e:A (PRO264) to (THR307) HUMAN DIPEPTIDYL PEPTIDASE IV/CD26 MUTANT Y547F | ALPHA/BETA HYDROLASE, BETA-PROPELLER, HOMODIMER, HYDROLASE
2i0a:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF KB-19 COMPLEXED WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2i4u:B (VAL211) to (GLU234) HIV-1 PROTEASE WITH TMC-126 | PROTEIN INHIBITOR COMPLEX, HYDROLASE
2i4v:B (ARG208) to (GLU234) HIV-1 PROTEASE I84V, L90M WITH TMC126 | HIV-1 PROTEIN INHIBITOR MUTANT, HYDROLASE
2i4x:B (ARG208) to (GLU234) HIV-1 PROTEASE I84V, L90M WITH GS-8374 | HIV-1 PROTEASE I84VL90M INHIBITOR, HYDROLASE
1ijc:A (MET1) to (ASN29) SOLUTION STRUCTURE OF BUCANDIN, A NEUROTOXIN FROM THE VENOM OF THE MALAYAN KRAIT | THREE-FINGER MOTIF, TWO ANTIPARALLEL BETA-SHEETS, TWO AND FOUR STRANDED BETA-SHEETS, TOXIN
1ukh:A (ASN9) to (PRO31) STRUCTURAL BASIS FOR THE SELECTIVE INHIBITION OF JNK1 BY THE SCAFFOLDING PROTEIN JIP1 AND SP600125 | TRANSFERASE, PHOSPHORYLATION
5a8f:C (VAL14) to (GLY35) STRUCTURE AND GENOME RELEASE MECHANISM OF HUMAN CARDIOVIRUS SAFFOLD VIRUS-3 | VIRAL PROTEIN, SAFFOLD, VIRUS, CARDIOVIRUS, PICORNAVIRALES, A, ALTERED, VIRION, PARTICLE, CAPSID, GENOME, RNA, SSRNA
2i9b:G (ASN52) to (SER100) CRYSTAL STRUCTURE OF ATF-UROKINASE RECEPTOR COMPLEX | UROKINASE RECEPTOR, KRINGLE DOMAIN, GROWTH FACTOR-LIKE DOMAIN, HYDROLASE
2i9b:H (ASN52) to (SER100) CRYSTAL STRUCTURE OF ATF-UROKINASE RECEPTOR COMPLEX | UROKINASE RECEPTOR, KRINGLE DOMAIN, GROWTH FACTOR-LIKE DOMAIN, HYDROLASE
1uoj:B (ALA64) to (ALA86) CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN 1 IN THE CALCIUM-FREE STATE | SUGAR BINDING PROTEIN, GALACTOSE BINDING
4m5d:A (ASP437) to (ASP469) CRYSTAL STRUCTURE OF THE UTP22 AND RRP7 COMPLEX FROM SACCHAROMYCES CEREVISIAE | NUCLEOLUS, RNA BINDING PROTEIN
5aam:J (LYS305) to (ASP341) STRUCTURE OF A REDESIGNED CROSS-REACTIVE ANTIBODY TO DENGUE VIRUS WITH INCREASED IN VIVO POTENCY | IMMUNE SYSTEM, SCFV DENGUE ANTIBODY ENVELOPE DOMAIN III
4m8x:A (PRO9) to (GLU34) GS-8374, A NOVEL PHOSPHONATE-CONTAINING INHIBITOR OF HIV-1 PROTEASE, EFFECTIVELY INHIBITS HIV PR MUTANTS WITH AMINO ACID INSERTIONS | HIV PROTEASE, ASPARTIC PROTEASE, GS8374, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2ieo:B (VAL111) to (GLU134) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT I84V WITH A POTENT NON-PEPTIDE INHIBITOR (UIC-94017) | HIV-1 PROTEASE, MUTANT, I84V, DIMER, INHIBITOR, UIC-94017, TMC114, DARUNAVIR, HYDROLASE
5ab2:B (SER221) to (GLU245) CRYSTAL STRUCTURE OF AMINOPEPTIDASE ERAP2 WITH LIGAND | AMINOPEPTIDASE, ERAP2, ZINC ION BINDING, ENDOPLASMIC RETICULUM, HYDROLASE, METALLOPROTEASE, L-RAP, ANTIGEN PRESENTATION
5abj:B (VAL13) to (ALA34) STRUCTURE OF COXSACKIEVIRUS A16 IN COMPLEX WITH GPP3 | VIRUS, INHIBITOR
1usv:G (ASN340) to (GLU372) THE STRUCTURE OF THE COMPLEX BETWEEN AHA1 AND HSP90 | CHAPERONE/COMPLEX, CHAPERONE, ACTIVATOR, HSP90
4mc1:B (VAL11) to (GLU34) HIV PROTEASE IN COMPLEX WITH SA526P | CARBAMATES, DRUG DESIGN, HIV PROTEASE INHIBITORS, PROTEIN BINDING, STEREOISOMERISM, STRUCTURE-ACTIVITY RELATIONSHIP, THIAZEPINES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4mc2:B (VAL11) to (GLU34) HIV PROTEASE IN COMPLEX WITH SA525P | CARBAMATES, DRUG DESIGN, HIV PROTEASE INHIBITORS, PROTEIN BINDING, STEREOISOMERISM, STRUCTURE-ACTIVITY RELATIONSHIP, THIAZEPINES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3wem:A (LYS845) to (GLU907) SUGAR BEET ALPHA-GLUCOSIDASE WITH ACARVIOSYL-MALTOTETRAOSE | ALPHA-GLUCOSIDASE, GLYCOSIDE HYDROLASE FAMILY 31, (BETA/ALPHA)8- BARREL, ACARBOSE DERIVATIVE, HYDROLASE
3j31:Q (ASP18) to (GLY47) LIFE IN THE EXTREMES: ATOMIC STRUCTURE OF SULFOLOBUS TURRETED ICOSAHEDRAL VIRUS | VIRUS ASSEMBLY, EVOLUTION, ARCHAEA, VIRUS
3j31:E (THR12) to (LEU38) LIFE IN THE EXTREMES: ATOMIC STRUCTURE OF SULFOLOBUS TURRETED ICOSAHEDRAL VIRUS | VIRUS ASSEMBLY, EVOLUTION, ARCHAEA, VIRUS
1ux6:A (ASP956) to (VAL980) STRUCTURE OF A THROMBOSPONDIN C-TERMINAL FRAGMENT REVEALS A NOVEL CALCIUM CORE IN THE TYPE 3 REPEATS | EXTRACELLULAR MATRIX, CALCIUM BINDING, L-TYPE LECTIN, GLYCOPROTEIN, CELL ADHESION, CALCIUM-BINDING, HEPARIN- BINDING, EGF-LIKE DOMAIN
1uxz:A (GLY16) to (TYR42) CARBOHYDRATE BINDING MODULE (CBM6CM-2) FROM CELLVIBRIO MIXTUS LICHENASE 5A | CARBOHYDRATE BINDING MODULE, CBM6, MIXTED BETA1, 3-1, 4 LINKED GLUCAN
1uy0:A (GLY16) to (TYR42) CARBOHYDRATE BINDING MODULE (CBM6CM-2) FROM CELLVIBRIO MIXTUS LICHENASE 5A IN COMPLEX WITH GLC-1,3-GLC-1,4-GLC-1,3-GLC | CARBOHYDRATE BINDING MODULE, CBM6, MIXTED BETA1, 3-1, 4 LINKED GLUCAN
1uy0:B (GLY16) to (TYR42) CARBOHYDRATE BINDING MODULE (CBM6CM-2) FROM CELLVIBRIO MIXTUS LICHENASE 5A IN COMPLEX WITH GLC-1,3-GLC-1,4-GLC-1,3-GLC | CARBOHYDRATE BINDING MODULE, CBM6, MIXTED BETA1, 3-1, 4 LINKED GLUCAN
1uyj:A (LEU252) to (ARG286) CLOSTRIDIUM PERFRINGENS EPSILON TOXIN SHOWS STRUCTURAL SIMILARITY WITH THE PORE FORMING TOXIN AEROLYSIN | TOXIN, BETA PORE FORMING TOXIN
1izi:A (PRO9) to (GLU34) INHIBITOR OF HIV PROTEASE WITH UNUSUAL BINDING MODE POTENTLY INHIBITING MULTI-RESISTANT PROTEASE MUTANTS | HIV-1 PROTEINASE, TRIPLE MUTANT, POTENT INHIBITOR, SUBSITE BINDING, HYDROLASE
2in0:A (ARG54) to (ALA94) CRYSTAL STRUCTURE OF MTU RECA INTEIN SPLICING DOMAIN | HYDROLASE
1uyx:A (GLY16) to (TYR42) CARBOHYDRATE BINDING MODULE (CBM6CM-2) FROM CELLVIBRIO MIXTUS LICHENASE 5A IN COMPLEX WITH CELLOBIOSE | CARBOHYDRATE BINDING MODULE, CBM6, MIXTED BETA1, 3-1, 4 LINKED GLUCAN, CELLOBIOSE
1uyx:B (GLY16) to (TYR42) CARBOHYDRATE BINDING MODULE (CBM6CM-2) FROM CELLVIBRIO MIXTUS LICHENASE 5A IN COMPLEX WITH CELLOBIOSE | CARBOHYDRATE BINDING MODULE, CBM6, MIXTED BETA1, 3-1, 4 LINKED GLUCAN, CELLOBIOSE
1uz0:A (GLY16) to (TYR42) CARBOHYDRATE BINDING MODULE (CBM6CM-2) FROM CELLVIBRIO MIXTUS LICHENASE 5A IN COMPLEX WITH GLC-4GLC-3GLC-4GLC | CARBOHYDRATE BINDING MODULE, CBM6, MIXED BETA1, 3-1, 4 LINKED GLUCAN
1uz6:E (ILE2) to (LEU33) ANTI-LEWIS X FAB FRAGMENT UNCOMPLEXED | IMMUNE SYSTEM, ANTIBODY/COMPLEX, ANTIBODY, ANTI-CARBOHYDRATE
5agz:A (VAL11) to (GLU34) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
5ah6:A (VAL11) to (GLU34) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
5ah6:B (VAL111) to (GLU134) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
5ah7:A (VAL11) to (GLU34) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON-PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
5ah7:B (VAL111) to (GLU134) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON-PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
5ah8:A (VAL11) to (GLU34) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON-PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
5ah8:B (VAL111) to (GLU134) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON-PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
5ah9:B (VAL111) to (GLU134) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
5aha:A (VAL11) to (GLU34) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
5aha:B (VAL111) to (GLU134) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
5ahb:A (VAL11) to (GLU34) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON-PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
5ahb:B (VAL111) to (GLU134) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON-PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
2iou:A (THR274) to (ASN311) MAJOR TROPISM DETERMINANT P1 (MTD-P1) VARIANT COMPLEXED WITH BORDETELLA BROCHISEPTICA VIRULENCE FACTOR PERTACTIN EXTRACELLULAR DOMAIN (PRN-E). | MTD; PRN; PERTACTIN, VIRAL PROTEIN-MEMBRANE PROTEIN COMPLEX
1j1l:A (GLY154) to (ASP177) CRYSTAL STRUCTURE OF HUMAN PIRIN: A BCL-3 AND NUCLEAR FACTOR I INTERACTING PROTEIN AND A CUPIN SUPERFAMILY MEMBER | BETA SANDWICH, CUPIN, IRON, METATL BINDING PROTEIN
4mhh:C (ASN150) to (PRO185) CRYSTAL STRUCTURE OF FAB H5M9 IN COMPLEX WITH INFLUENZA VIRUS HEMAGGLUTININ FROM A/VIET NAM/1203/2004 (H5N1) | H5N1 INFLUENZA VIRUS, BROADLY NEUTRALIZING MURINE ANTIBODY, ESCAPE MUTANT, PASSIVE IMMUNOTHERAPY, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
2iq7:C (GLY48) to (GLY72) CRYSTAL STRUCTURE OF THE POLYGALACTURONASE FROM COLLETOTRICHUM LUPINI AND ITS IMPLICATIONS FOR THE INTERACTION WITH POLYGALACTURONASE- INHIBITING PROTEINS | PARALLEL BETA HELIX, HYDROLASE
2iq7:D (GLY48) to (GLY72) CRYSTAL STRUCTURE OF THE POLYGALACTURONASE FROM COLLETOTRICHUM LUPINI AND ITS IMPLICATIONS FOR THE INTERACTION WITH POLYGALACTURONASE- INHIBITING PROTEINS | PARALLEL BETA HELIX, HYDROLASE
2iq7:E (GLY48) to (GLY72) CRYSTAL STRUCTURE OF THE POLYGALACTURONASE FROM COLLETOTRICHUM LUPINI AND ITS IMPLICATIONS FOR THE INTERACTION WITH POLYGALACTURONASE- INHIBITING PROTEINS | PARALLEL BETA HELIX, HYDROLASE
2iq7:F (GLY48) to (GLY72) CRYSTAL STRUCTURE OF THE POLYGALACTURONASE FROM COLLETOTRICHUM LUPINI AND ITS IMPLICATIONS FOR THE INTERACTION WITH POLYGALACTURONASE- INHIBITING PROTEINS | PARALLEL BETA HELIX, HYDROLASE
2iq7:G (GLY48) to (GLY72) CRYSTAL STRUCTURE OF THE POLYGALACTURONASE FROM COLLETOTRICHUM LUPINI AND ITS IMPLICATIONS FOR THE INTERACTION WITH POLYGALACTURONASE- INHIBITING PROTEINS | PARALLEL BETA HELIX, HYDROLASE
2x5i:B (VAL12) to (GLY33) CRYSTAL STRUCTURE ECHOVIRUS 7 | VIRUS, CAPSID PROTEIN
2iuk:B (GLY1082) to (LYS1126) CRYSTAL STRUCTURE OF SOYBEAN LIPOXYGENASE-D | IRON, DIOXYGENASE, METAL-BINDING, OXIDOREDUCTASE, OXYLIPIN BIOSYNTHESIS, SOYBEAN LIPOXYGENASE-D, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS
1jcv:A (GLY85) to (ILE119) REDUCED BRIDGE-BROKEN YEAST CU/ZN SUPEROXIDE DISMUTASE LOW TEMPERATURE (-180C) STRUCTURE | OXIDOREDUCTASE, OXIDOREDUCTASE (SUPEROXIDE ACCEPTOR)
3wnp:A (VAL433) to (ALA461) D308A, F268V, D469Y, A513V, AND Y515S QUINTUPLE MUTANT OF BACILLUS CIRCULANS T-3040 CYCLOISOMALTOOLIGOSACCHARIDE GLUCANOTRANSFERASE COMPLEXED WITH ISOMALTOUNDECAOSE | C2 TYPE IMMUNOGLOBULIN FOLD, (BETA/ALPHA)8-BARREL, BETA-JELLY ROLL, GREEK KEY, GLYCOSIDE HYDROLASE, ALPHA-1,6-GLUCAN, TRANSFERASE
1jd9:A (VAL420) to (LYS443) CRYSTAL STRUCTURE ANALYSIS OF THE MUTANT K300Q OF PSEUDOALTEROMONAS HALOPLANCTIS ALPHA-AMYLASE | ALPHA-BETA BARREL, GLYCOSYL HYDROLASE, ALLOSTERIC ACTIVATION
3wov:A (PHE735) to (ASN774) CRYSTAL STRUCTURE OF THE C-TERMINAL GLOBULAR DOMAIN OF OLIGOSACCHARYLTRANSFERASE (PAAGLB-L, Q9V250_PYRAB, PAB2202) FROM PYROCOCCUS ABYSSI | TRANFERASE, OLIGOSACCHARIDE, TRANSFERASE
1vf5:Q (GLY130) to (HIS152) CRYSTAL STRUCTURE OF CYTOCHROME B6F COMPLEX FROM M.LAMINOSUS | PHOTOSYNTHESIS, MEMBRANE PROTEIN COMPLEX, ELECTRON TRANSFER COMPLEX
3wqh:B (ASN263) to (THR307) CRYSTAL STRUCTURE OF HUMAN DPP-IV IN COMPLEX WITH ANAGLIPTIN | DIABETES, BETA-PROPELLER, AMINOPEPTIDASE, MEMBRANE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
1jm6:A (GLN1333) to (PRO1364) PYRUVATE DEHYDROGENASE KINASE, ISOZYME 2, CONTAINING ADP | KINASE, MITOCHONDION, SERINE KINASE, TRANSFERASE
1jma:B (ASP7) to (VAL25) CRYSTAL STRUCTURE OF THE HERPES SIMPLEX VIRUS GLYCOPROTEIN D BOUND TO THE CELLULAR RECEPTOR HVEA/HVEM | V-TYPE IG MOLECULE AND TNFR SUPERFAMILY, VIRAL PROTEIN
1vik:A (VAL11) to (GLU34) HIV-1 PROTEASE COMPLEXED WITH THE INHIBITOR HOE/BAY 793 ORTHORHOMBIC FORM | ASPARTYL PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS, HOE/BAY 793: INHIBITOR DESIGN
3wst:H (ILE283) to (TYR307) CRYSTAL STRUCTURE OF C.ELEGANS PRMT7 IN COMPLEX WITH SAH(P31) | ROSSMANN FOLD, TRANSFERASE
3wvz:B (LEU10) to (PHE39) CRYSTAL STRUCTURE OF HIKESHI, A NEW NUCLEAR TRANSPORT RECEPTOR OF HSP70 | NUCLEAR TRANSPORT RECEPTOR, TRANSPORT PROTEIN
5aws:A (PRO687) to (ASN722) CRYSTAL STRUCTURE OF THE SGIP1 MU HOMOLOGY DOMAIN IN THE P1 SPACE GROUP | ENDOCYTOSIS, PROTEIN-PROTEIN INTERACTION
5aws:B (PRO687) to (ASN722) CRYSTAL STRUCTURE OF THE SGIP1 MU HOMOLOGY DOMAIN IN THE P1 SPACE GROUP | ENDOCYTOSIS, PROTEIN-PROTEIN INTERACTION
5awt:A (PRO687) to (ASN722) CRYSTAL STRUCTURE OF THE SGIP1 MU HOMOLOGY DOMAIN IN COMPLEX WITH AN EPS15 FRAGMENT CONTAINING TWO DPF MOTIFS (YDPFGGDPFKG) | ENDOCYTOSIS, PROTEIN-PROTEIN INTERACTION
5awu:A (PRO687) to (ASN722) CRYSTAL STRUCTURE OF THE SGIP1 MU HOMOLOGY DOMAIN IN COMPLEX WITH AN EPS15 FRAGMENT CONTAINING TWO DPF MOTIFS (YDPFKGSDPFA) | ENDOCYTOSIS, PROTEIN-PROTEIN INTERACTION
3wwn:B (MET1) to (CYS25) CRYSTAL STRUCTURE OF LYSZ FROM THERMUS THERMOPHILUS COMPLEX WITH LYSW | ZINC FINGER, AMINO ACID KINASE, METAL BINDING PROTEIN-TRANSFERASE COMPLEX
5ayf:A (LEU169) to (PHE193) CRYSTAL STRUCTURE OF SET7/9 IN COMPLEX WITH CYPROHEPTADINE | SET DOMAIN, METHYLTRANSFERASE, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1w18:A (GLN367) to (ARG402) CRYSTAL STRUCTURE OF LEVANSUCRASE FROM GLUCONACETOBACTER DIAZOTROPHICUS | TRANSFERASE, FRUCTOSYL TRANSFERASE, GLYCOSYLTRANSFERASE
5b0r:B (GLU57) to (ILE109) BETA-1,2-MANNOBIOSE PHOSPHORYLASE FROM LISTERIA INNOCUA - BETA-1,2- MANNOBIOSE COMPLEX | GLYCOSIDE PHOSPHORYLASE, TRANSFERASE
5b0s:B (GLU57) to (ILE109) BETA-1,2-MANNOBIOSE PHOSPHORYLASE FROM LISTERIA INNOCUA - BETA-1,2- MANNOTRIOSE COMPLEX | GLYCOSIDE PHOSPHORYLASE, TRANSFERASE
5b0w:A (GLY104) to (GLY122) CRYSTAL STRUCTURE OF THE 11-CIS ISOMER OF PHARAONIS HALORHODOPSIN IN THE ABSENCE OF HALIDE IONS | SEVEN TRANS-MEMBRANE HELICES, RETINYLIDENE PROTEIN, LIGHT-DRIVEN CHLORIDE ION PUMP MICROBIAL RHODOPSIN, MEMBRANE PROTEIN
4n20:A (ARG3) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (0 MM CA2+) | DEIMINASE, HYDROLASE
4n22:A (ARG3) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (50 UM CA2+) | DEIMINASE, HYDROLASE
4n24:A (ARG3) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (100 UM CA2+) | DEIMINASE, HYDROLASE
4n25:A (ARG3) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (250 UM CA2+) | DEIMINASE, HYDROLASE
4n26:A (ARG3) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (500 UM CA2+) | DEIMINASE, HYDROLASE
4n2a:A (ARG5) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (5 MM CA2+) | DEIMINASE, HYDROLASE
4n2d:A (ARG3) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (D123N, 0 MM CA2+) | DEIMINASE, HYDROLASE
4n2e:A (ARG3) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (D123N, 10 MM CA2+) | DEIMINASE, HYDROLASE
4n2f:A (LEU2) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (D169A, 0 MM CA2+) | DEIMINASE, HYDROLASE
4n2h:A (ARG3) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (D177A, 0 MM CA2+) | DEIMINASE, HYDROLASE
4n2i:A (LEU2) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (D177A, 10 MM CA2+) | DEIMINASE, HYDROLASE
4n2k:A (ARG3) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (Q350A, 0 MM CA2+) | DEIMINASE, HYDROLASE
4n2l:A (ARG5) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (Q350A, 10 MM CA2+) | DEIMINASE, HYDROLASE
5b2p:A (PRO1480) to (PRO1509) CRYSTAL STRUCTURE OF FRANCISELLA NOVICIDA CAS9 IN COMPLEX WITH SGRNA AND TARGET DNA (TGA PAM) | CRISPR-CAS9, GENOME ENGINEERING, HYDROLASE-RNA-DNA COMPLEX
4n53:B (VAL13) to (GLY34) HUMAN ENTEROVIRUS 71 UNCOATING INTERMEDIATE CAPTURED AT ATOMIC RESOLUTION | HAND-FOOT-AND-MOUTH DISEASE, HUMAN ENTEROVIRUS 71, VIRION, POCKET FACTOR, PICORNAVIRUS, ICOSAHEDRAL VIRUS, VIRUS
2je8:A (THR787) to (ASP812) STRUCTURE OF A BETA-MANNOSIDASE FROM BACTEROIDES THETAIOTAOMICRON | BETA-MANNOSIDASE, GLYCOSIDE HYDROLASE, HYDROLASE
2je8:B (SER788) to (ASP812) STRUCTURE OF A BETA-MANNOSIDASE FROM BACTEROIDES THETAIOTAOMICRON | BETA-MANNOSIDASE, GLYCOSIDE HYDROLASE, HYDROLASE
5bnn:B (VAL13) to (ALA34) CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS D68 IN COMPLEX WITH 6'SL | ENTEROVIRUS, CAPSID, BETA JELLY ROLL, RECEPTOR, ICOSAHEDRAL VIRUS, VIRUS
5bno:B (VAL13) to (ALA34) CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS D68 IN COMPLEX WITH 6'SLN | ENTEROVIRUS, CAPSID, BETA JELLY ROLL, VIRUS, RECEPTOR
3zfe:B (VAL13) to (GLY34) HUMAN ENTEROVIRUS 71 IN COMPLEX WITH CAPSID BINDING INHIBITOR WIN51711 | EV71, VIRUS, PICORNAVIRUS
4n8m:E (PRO14) to (LEU44) STRUCTURAL POLYMORPHISM IN THE N-TERMINAL OLIGOMERIZATION DOMAIN OF NPM1 | HISTONE CHAPERONE, NUCLEOLAR PROTEIN, PHOSPHOPROTEIN, STRUCTURAL POLYMORPHISM, PENTAMER, RIBOSOME BIOGENESIS, REGULATED UNFOLDING, CHAPERONE
2jid:A (PRO264) to (THR307) HUMAN DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH 1-(3,4- DIMETHOXY-PHENYL)-3-M-TOLYL-PIPERIDINE-4-YLAMINE | HYDROLASE, DIABETES TYPE II, DIPEPTIDYL PEPTIDASE, PROTEASE, MEMBRANE, B-PROPELLER, STRUCTURE BASED DESIGN, GLYCOPROTEIN, SIGNAL-ANCHOR, TRANSMEMBRANE, HYDROLASE FOLD, AMINOPEPTIDASE, SERINE PROTEASE
3zgi:B (GLY288) to (ASN320) CRYSTAL STRUCTURE OF THE KRT10-BINDING REGION DOMAIN OF THE PNEUMOCOCCAL SERINE RICH REPEAT PROTEIN PSRP | STRUCTURAL PROTEIN, ADHESIN, KERATIN-10, SRRP
3zgi:C (GLY288) to (ASN320) CRYSTAL STRUCTURE OF THE KRT10-BINDING REGION DOMAIN OF THE PNEUMOCOCCAL SERINE RICH REPEAT PROTEIN PSRP | STRUCTURAL PROTEIN, ADHESIN, KERATIN-10, SRRP
1k1t:B (THR112) to (GLU134) COMBINING MUTATIONS IN HIV-1 PROTEASE TO UNDERSTAND MECHANISMS OF RESISTANCE | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1k1u:B (THR112) to (GLU134) COMBINING MUTATIONS IN HIV-1 PROTEASE TO UNDERSTAND MECHANISMS OF RESISTANCE | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1k1y:A (LYS593) to (PRO620) CRYSTAL STRUCTURE OF THERMOCOCCUS LITORALIS 4-ALPHA-GLUCANOTRANSFERASE COMPLEXED WITH ACARBOSE | 4-ALPHA-GLUCANOTRANSFERASE COMPLEXED WITH ACARBOSE, TRANSFERASE
5bry:B (ARG8) to (GLU34) HIV-1 WILD TYPE PROTEASE WITH GRL-011-11A (A METHYLAMINE BIS- TETRAHYDROFURAN P2-LIGAND, SULFONAMIDE ISOSTERE DERIVATE) | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1wbk:B (VAL11) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH ASYMMETRIC INHIBITOR, BEA568 | HYDROLASE/INHIBITOR, HYDROLASE/INHIBITOR COMPLEX, AIDS, ASPARTYL PROTEASE, DIMER, HYDROLASE, HYDROLASE/HYDROLASE INHIBITOR, PROTEIN-INHIBITOR COMPLEX
1wcf:A (TYR42) to (ALA73) 1.54 A CRYSTAL STRUCTURE OF RV3628, MYCOBACTERIUM TUBERCULOSIS INORGANIC PYROPHOSPHATASE (PPASE) AT PH7.0 | STRUCTURAL GENOMICS, POTASSIUM, HYDROLASE
5bxd:D (ALA30) to (ASP78) CRYSTAL STRUCTURE OF PENTAMERIC KCTD1 BTB DOMAIN FORM 2 | PROTEIN BINDING
2y2e:C (HIS75) to (GLU118) CRYSTAL STRUCTURE OF AMPD GROWN AT PH 5.5 | HYDROLASE, PEPTIDOGLYCAN AMIDASE, AMIDASE_2 FAMILY, ACTIVATION MECHANISM
4ni3:A (ARG406) to (VAL431) CRYSTAL STRUCTURE OF GH29 FAMILY ALPHA-L-FUCOSIDASE FROM FUSARIUM GRAMINEARUM IN THE CLOSED FORM | FUCOSIDASE, GH29, GLYCOSIDE HYDROLASE, TIM BARREL, CRYSTALLIN, HYDROLASE
3zlc:A (THR233) to (ASN284) CRYSTAL STRUCTURE OF ERV41P | PROTEIN TRANSPORT, EARLY SECRETORY PATHWAY, ENDOPLASMIC RETICULUM, COPII VESICLE
4nkk:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF A MULTI-DRUG RESISTANT CLINICAL ISOLATE-769 HIV-1 PROTEASE VARIANT THAT IS RESISTANT TO THE DIMERIZATION INHIBITORY ACTIVITY OF TLF-PAFF | HIV, AIDS, HIV-1 PROTEASE, DIMERIZATION INHIBITORS, PROTEASE INHIBITORS, MULTIDRUG-RESISTANCE, CLINICAL ISOLATE 769, DIMER PROTEASE, HYDROLASE
5c08:E (ARG64) to (LEU96) 1E6 TCR IN COMPLEX WITH HLA-A0E CARRYING RQWGPDPAAV | IMMUNO, HLA-A02, 1E6-TCR, CROSS-REACTIVITY, IMMUNE SYSTEM
2y5p:D (TYR323) to (LYS389) B-REPEAT OF LISTERIA MONOCYTOGENES INLB (INTERNALIN B) | PROTEIN BINDING, VIRULENCE FACTOR, PATHOGENICITY FACTOR, BETA-GRASP FOLD
3zps:B (VAL111) to (GLU134) DESIGN AND SYNTHESIS OF P1-P3 MACROCYCLIC TERTIARY ALCOHOL COMPRISING HIV-1 PROTEASE INHIBITORS | HYDROLASE, PROTEASE INHIBITOR, RATIONAL DRUG DESIGN,
3zpt:B (VAL111) to (GLU134) DESIGN AND SYNTHESIS OF P1-P3 MACROCYCLIC TERTIARY ALCOHOL COMPRISING HIV-1 PROTEASE INHIBITORS | HYDROLASE, RATIONAL DRUG DESIGN, MACROCYCLIC TERTIARY ALCOHOL
3zpu:B (VAL111) to (GLU134) DESIGN AND SYNTHESIS OF P1-P3 MACROCYCLIC TERTIARY ALCOHOL COMPRISING HIV-1 PROTEASE INHIBITORS | HYDROLASE, PROTEASE INHIBITOR, RATIONAL DRUG DESIGN
3jbd:2 (VAL13) to (ALA34) COMPLEX OF POLIOVIRUS WITH VHH PVSP6A | VHH, NANOBODY, POLIOVIRUS, VIRUS-IMMUNE SYSTEM COMPLEX
1kj7:A (VAL11) to (GLU34) SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES | P2-NUCLEOCAPSID, SUBSTRATE RECOGNITION, HYDROLASE
1kj7:B (VAL11) to (GLU34) SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES | P2-NUCLEOCAPSID, SUBSTRATE RECOGNITION, HYDROLASE
1kjg:A (VAL11) to (GLU34) SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES | REVERSE TRANSCRIPTASE, RNASE H, SUBSTRATE RECOGNITION, HYDROLASE
1kjh:B (ARG8) to (GLU34) SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES | RNASE H, INTEGRASE, SUBSTRATE RECOGNITION, HYDROLASE
3zss:C (TRP75) to (GLY108) APO FORM OF GLGE ISOFORM 1 FROM STREPTOMYCES COELICOLOR | HYDROLASE, ALPHA-GLUCAN BIOSYNTHESIS, GLYCOSIDE HYDROLASE FAMILY 13_3
4nql:C (MET1) to (LEU69) THE CRYSTAL STRUCTURE OF THE DUB DOMAIN OF AMSH ORTHOLOGUE, SST2 FROM S. POMBE, IN COMPLEX WITH LYSINE 63-LINKED DIUBIQUITIN | JAMM DOMAIN, ZINC METALLOPROTEASE, PROTEIN COMPLEX, AMSH, HEIX-BETA- HELIX SANDWICH, HYDROLASE, METAL BINDING, K63-LINKED DIUBIQUITIN, HELIX-BETA-HELIX SANDWICH, DEUBIQUITINASE, UBIQUITIN, HSE1, CYTOSOL, ENDOSOME, HYDROLASE-PROTEIN BINDING COMPLEX
1knb:A (ASP418) to (ASP462) CRYSTAL STRUCTURE OF THE RECEPTOR-BINDING DOMAIN OF ADENOVIRUS TYPE 5 FIBER PROTEIN AT 1.7 ANGSTROMS RESOLUTION | CELL RECEPTOR RECOGNITION
4nre:A (GLY31) to (PRO77) THE STRUCTURE OF HUMAN 15-LIPOXYGENASE-2 WITH A SUBSTRATE MIMIC | CALCIUM BINDING, OXIDOREDUCTASE
5c5k:A (GLY270) to (PRO299) STRUCTURE OF THE PFR FORM OF A CANONICAL PHYTOCHROME | PHOTOSENSOR, TRANSFERASE
1ktk:B (ASN96) to (PHE129) COMPLEX OF STREPTOCOCCAL PYROGENIC ENTEROTOXIN C (SPEC) WITH A HUMAN T CELL RECEPTOR BETA CHAIN (VBETA2.1) | STREPTOCOCCUS, IMMUNITY, T CELL RECEPTOR BETA, IMMUNE SYSTEM
2ygc:B (ARG233) to (TYR263) STRUCTURE OF VACCINIA VIRUS D13 SCAFFOLDING PROTEIN | VIRAL PROTEIN, VIRAL EVOLUTION
4nzd:A (LYS134) to (LEU167) INTERLEUKIN 21 RECEPTOR | FIBRONECTINE III DOMAIN, INTERLEUKIN 21, GLYCOSYLATED, SIGNALING PROTEIN
1kxt:D (GLY97) to (GLN105) CAMELID VHH DOMAINS IN COMPLEX WITH PORCINE PANCREATIC ALPHA-AMYLASE | ALPHA 8 BETA 8; BETA BARREL, HYDROLASE, IMMUNE SYSTEM
2nli:B (SER77) to (MET91) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN L-LACTATE OXIDASE AND A SUBSTRATE ANALOGUE AT 1.59 ANGSTROM RESOLUTION | L-LACTATE OXIDASE, FLAVOENZYME, FMN, D-LACTATE, OXIDOREDUCTASE
4nzr:M (VAL310) to (ASP339) CRYSTAL STRUCTURE OF THE ANTIBODY-BINDING REGION OF PROTEIN M (PROTEIN M TD) IN COMPLEX WITH ANTI-HIV ANTIBODY PGT135 FAB | LEUCINE-RICH REPEAT, BROAD ANTIBODY-BINDING, BLOCK ANTIBODY-ANTIGEN UNION, VARIABLE REGION, IMMUNE SYSTEM-PROTEIN BINDING COMPLEX
4nzt:M (VAL310) to (LEU340) CRYSTAL STRUCTURE OF THE ANTIBODY-BINDING REGION OF PROTEIN M (PROTEIN M TD) IN COMPLEX WITH ANTI-INFLEUNZA HEMAGGLUTININ ANTIBODY CR9114 FAB | LEUCINE-RICH REPEAT, BROAD ANTIBODY-BINDING, BLOCK ANTIBODY-ANTIGEN UNION, VARIABLE REGION, PROTEIN BINDING-IMMUNE SYSTEM COMPLEX
1ky9:B (SER28) to (THR102) CRYSTAL STRUCTURE OF DEGP (HTRA) | PROTEIN QUALITY CONTROL, SERINE PROTEASE, TRYPSIN, CHAPERONE, PDZ, ATP-INDEPENDENT, TEMPERATURE-REGULATED, PERIPLASM, CAGE-FORMING PROTEIN, HYDROLASE
2nmz:B (THR112) to (GLU134) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A INHIBITOR SAQUINAVIR | HIV-1 PROTEASE, MUTANT, V82A, DIMER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2nmy:B (ARG108) to (GLU134) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A INHIBITOR SAQUINAVIR | HIV-1 PROTEASE, MUTANT, V82A, DIMER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1kzk:B (VAL11) to (GLU34) JE-2147-HIV PROTEASE COMPLEX | HIV PROTEASE COMPLEX, ANISOTROPIC DISPLACEMENT PARAMETERS, VIRAL PROTEIN, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5cad:A (LYS48) to (VAL75) CRYSTAL STRUCTURE OF THE VICILIN FROM SOLANUM MELONGENA REVEALED EXISTENCE OF DIFFERENT ANIONIC LIGANDS IN STRUCTURALLY SIMILAR POCKETS | SOLANACEAE; SOLANUM MELONGENA;7S VICILIN; SM80.1, PLANT PROTEIN
3jv5:A (ASN227) to (TYR263) CRYSTAL STRUCTURE OF THE DIMERIZATION DOMAINS P52 HOMODIMER | NF-KB PROTEIN, P52 HOMODIMER, DIMERIZATION DOMAIN, ACTIVATOR, ANK REPEAT, DNA-BINDING, ISOPEPTIDE BOND, NUCLEUS, PHOSPHOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION
3jwn:E (SER113) to (TYR153) COMPLEX OF FIMC, FIMF, FIMG AND FIMH | FIMBRIA, CELL ADHESION, FIMH, FIMC, FIMF,FIMG, CHAPERONE, FIBRIUM, IMMUNOGLOBULIN DOMAIN, FIMBRIUM, PERIPLASM, DISULFIDE BOND, PROTEIN BINDING-CELL ADHESION COMPLEX
3jwn:K (SER113) to (GLN154) COMPLEX OF FIMC, FIMF, FIMG AND FIMH | FIMBRIA, CELL ADHESION, FIMH, FIMC, FIMF,FIMG, CHAPERONE, FIBRIUM, IMMUNOGLOBULIN DOMAIN, FIMBRIUM, PERIPLASM, DISULFIDE BOND, PROTEIN BINDING-CELL ADHESION COMPLEX
5cfc:C (VAL14) to (GLY35) CRYSTAL STRUCTURE OF HUMAN CARDIOVIRUS SAFV-3 | VIRION, CAPSID, SAFFOLD VIRUS, PATHOGEN, VIRUS
5cfd:C (VAL14) to (GLY35) CRYSTAL STRUCTURE OF DTT TREATED HUMAN CARDIOVIRUS SAFV-3 | VIRION, CAPSID, DTT, SAFFOLD VIRUS, PATHOGEN, VIRUS
2yu2:A (GLN197) to (GLN226) CRYSTAL STRUCTURE OF HJHDM1A WITHOUT A-KETOGLUTARATE | JMJC-DOMAIN-CONTAINING HISTONE DEMETHYLASES, OXIDOREDUCTASE
4obd:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (L449F/S451N) | CO-EVOLUTION, RESISTANCE, HYDROLASES, HYDROLASE
4obd:B (ARG8) to (GLU34) CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (L449F/S451N) | CO-EVOLUTION, RESISTANCE, HYDROLASES, HYDROLASE
4obd:C (ARG8) to (GLU34) CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (L449F/S451N) | CO-EVOLUTION, RESISTANCE, HYDROLASES, HYDROLASE
4obf:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE VARIANT (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (S451N) | CO-EVOLUTION, RESISTANCE, HYDROLASE
4obf:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE VARIANT (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (S451N) | CO-EVOLUTION, RESISTANCE, HYDROLASE
4obf:C (VAL11) to (GLU34) CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE VARIANT (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (S451N) | CO-EVOLUTION, RESISTANCE, HYDROLASE
4obf:D (ARG8) to (GLU34) CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE VARIANT (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (S451N) | CO-EVOLUTION, RESISTANCE, HYDROLASE
4obg:A (ARG8) to (GLU34) CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE. | CO-EVOLUTION, RESISTANCE, HYDROLASE
4obg:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF NELFINAVIR-RESISTANT, INACTIVE HIV-1 PROTEASE (D30N/N88D) IN COMPLEX WITH THE P1-P6 SUBSTRATE. | CO-EVOLUTION, RESISTANCE, HYDROLASE
4obh:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (L449F) | CO-EVOLUTION, RESISTANCE, HYDROLASE
4obj:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (S451N) | CO-EVOLUTION, RESISTANCE, HYDROLASE
4obj:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (S451N) | CO-EVOLUTION, RESISTANCE, HYDROLASE
4obk:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE P1-P6 SUBSTRATE VARIANT (L449F/S451N) | CO-EVOLUTION, RESISTANCE, HYDROLASE
2yxx:A (SER255) to (VAL297) CRYSTAL STRUCTURE ANALYSIS OF DIAMINOPIMELATE DECARBOXYLATE (LYSA) | TM1517, TIM BETA/ALPHA BARREL FOLD, LYASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
3k30:A (GLU16) to (VAL32) HISTAMINE DEHYDROGENASE FROM NOCARDIODES SIMPLEX | 6-S-CYSTEINYL-FMN, ADP BINDING SITE, OXIDOREDUCTASE
3k3p:A (LYS39) to (GLY95) CRYSTAL STRUCTURE OF THE APO FORM OF D-ALANINE:D-ALANINE LIGASE (DDL) FROM STREPTOCOCCUS MUTANS | D-ALANYL-ALANINE SYNTHETASE, ATP-BINDING, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, LIGASE, MAGNESIUM, MANGANESE, METAL-BINDING, NUCLEOTIDE-BINDING, PEPTIDOGLYCAN SYNTHESIS
4oh2:E (GLY85) to (VAL119) CRYSTAL STRUCTURE OF CU/ZN SUPEROXIDE DISMUTASE I149T | OXIDOREDUCTASE
2z3r:F (HIS11) to (ARG35) CRYSTAL STRUCTURE OF THE IL-15/IL-15RA COMPLEX | PROTEIN-PROTEIN COMPLEX, CYTOKINE-CYTOKINE RECEPTOR COMPLEX
2z3r:H (HIS11) to (ARG35) CRYSTAL STRUCTURE OF THE IL-15/IL-15RA COMPLEX | PROTEIN-PROTEIN COMPLEX, CYTOKINE-CYTOKINE RECEPTOR COMPLEX
2z3r:N (HIS11) to (ARG35) CRYSTAL STRUCTURE OF THE IL-15/IL-15RA COMPLEX | PROTEIN-PROTEIN COMPLEX, CYTOKINE-CYTOKINE RECEPTOR COMPLEX
2z3r:P (HIS11) to (ARG35) CRYSTAL STRUCTURE OF THE IL-15/IL-15RA COMPLEX | PROTEIN-PROTEIN COMPLEX, CYTOKINE-CYTOKINE RECEPTOR COMPLEX
2o10:A (ALA20) to (HIS52) SOLUTION STRUCTURE OF THE N-TERMINAL LIM DOMAIN OF MLP/CRP3 | LIM DOMAIN, ZINC BINDING, CRP, MLP, METAL BINDING PROTEIN
2z4o:B (VAL111) to (GLU134) WILD TYPE HIV-1 PROTEASE WITH POTENT ANTIVIRAL INHIBITOR GRL-98065 | HIV-1, WILD TYPE PROTEASE, PROTEASE INHIBITOR, HYDROLASE
5cmp:B (THR168) to (SER192) HUMAN FLRT3 LRR DOMAIN | LRR REPEATS, CELL ADHESION
4ohx:A (ARG56) to (SER81) C. ELEGANS CLP1 BOUND TO ADP AND MG2+ (RNA RELEASED STATE) | POLYNUCLEOTIDE KINASE, RNA BINDING PROTEIN
2o1v:A (TYR408) to (ASP440) STRUCTURE OF FULL LENGTH GRP94 WITH ADP BOUND | GRP94, HSP82, HSP90, HTPG, CHAPERONE, ADP, GP96, ENDOPLASMIN,
5cop:A (PRO9) to (GLU34) X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-097 | GRL-097, HIV-1 PROTEASE, PROTEASE-INHIBITOR, DARUNAVIR, TP-THF, NONPEPTIDIC, HYDROXYL, O-METHOXY., HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2o4l:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, I50V) IN COMPLEX WITH TIPRANAVIR | PROTEASE, VIRAL PROTEIN
2o4l:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, I50V) IN COMPLEX WITH TIPRANAVIR | PROTEASE, VIRAL PROTEIN
2o4s:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K) IN COMPLEX WITH LOPINAVIR | PROTEASE, VIRAL PROTEIN
5cpl:A (GLU6) to (TYR27) THE CRYSTAL STRUCTURE OF XENOBIOTIC REDUCTASE A (XENA) FROM PSEUDOMONAS PUTIDA IN COMPLEX WITH A NICOTINAMIDE MIMIC (MNH2) | REDUCTASE, NICOTINAMIDE MIMIC, BIOMIMETIC, OXIDOREDUCTASE
5cpm:A (GLU6) to (TYR27) XENA FROM PSEUDOMONAS PUTIDA IN COMPLEX WITH NADPH4. | XENA, OXIDOREDUCTASE
5cpm:B (GLU6) to (TYR27) XENA FROM PSEUDOMONAS PUTIDA IN COMPLEX WITH NADPH4. | XENA, OXIDOREDUCTASE
5cpn:A (GLU6) to (TYR27) CRYSTAL STRUCTURE OF XENA FROM PSEUDOMONAS PUTIDA IN COMPLEX WITH AN NADH MIMIC (MAC) | XENA, MNADH MIMIC, OXIDOREDUCTASE
5cpn:B (GLU6) to (PRO22) CRYSTAL STRUCTURE OF XENA FROM PSEUDOMONAS PUTIDA IN COMPLEX WITH AN NADH MIMIC (MAC) | XENA, MNADH MIMIC, OXIDOREDUCTASE
5cpo:A (GLU6) to (TYR27) CRYSTAL STRUCTURE OF XENA FROM PSEUDOMONAS PUTIDA IN COMPLEX WITH AN NADH MIMIC (MBU) | XENA, MIMIC MBU, OXIDOREDUCTASE
5cpo:B (GLU6) to (TYR27) CRYSTAL STRUCTURE OF XENA FROM PSEUDOMONAS PUTIDA IN COMPLEX WITH AN NADH MIMIC (MBU) | XENA, MIMIC MBU, OXIDOREDUCTASE
4a4q:B (VAL111) to (GLU134) STEREOSELECTIVE SYNTHESIS, X-RAY ANALYSIS, AND BIOLOGICAL EVALUATION OF A NEW CLASS OF LACTAM BASED HIV-1 PROTEASE INHIBITORS | HYDROLASE, GAMMA-BUTYROL-LACTAM, INHIBITOR
4oj5:A (LYS46) to (THR74) CRYSTAL STRUCTURE OF A PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
4oj5:B (LYS46) to (THR74) CRYSTAL STRUCTURE OF A PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
4oj5:C (LYS46) to (THR74) CRYSTAL STRUCTURE OF A PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
1xl2:A (ARG8) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH PYRROLIDINMETHANAMINE | ASPARTYL PROTEASE; HIV PROTEASE; PYRROLIDINE INHIBITOR, HYDROLASE
1xl5:B (VAL11) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH AMIDHYROXYSULFONE | ASPARTYL PROTEASE, HIV PROTEASE, AMIDHYDROXYSULFONE INHIBITOR, HYDROLASE
4ojl:A (LYS46) to (THR74) CRYSTAL STRUCTURE OF PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 IN COMPLEX WITH GLUCOSE | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
4a6c:A (VAL11) to (GLU34) STEREOSELECTIVE SYNTHESIS, X-RAY ANALYSIS, AND BIOLOGICAL EVALUATION OF A NEW CLASS OF LACTAM BASED HIV-1 PROTEASE INHIBITORS | HYDROLASE, GAMMA-BUTYROL-LACTAM
4ojo:A (LYS46) to (THR74) CRYSTAL STRUCTURE OF PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 IN COMPLEX WITH LACTOSE | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
4ojo:B (LYS46) to (THR74) CRYSTAL STRUCTURE OF PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 IN COMPLEX WITH LACTOSE | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
4ojo:C (LYS46) to (THR74) CRYSTAL STRUCTURE OF PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 IN COMPLEX WITH LACTOSE | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
4ojp:A (LYS46) to (THR74) CRYSTAL STRUCTURE OF PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 IN COMPLEX WITH MALTOSE | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
4ojp:B (LYS46) to (THR74) CRYSTAL STRUCTURE OF PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 IN COMPLEX WITH MALTOSE | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
4ojp:C (LYS46) to (THR74) CRYSTAL STRUCTURE OF PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120 IN COMPLEX WITH MALTOSE | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
4oju:B (LYS137) to (GLU164) CRYSTAL STRUCTURE OF A LEUCINE-RICH REPEAT PROTEIN (BACCAP_00569) FROM BACTEROIDES CAPILLOSUS ATCC 29799 AT 2.00 A RESOLUTION | LEUCINE RICH REPEATS,PF13306 FAMILY PROTEIN, PUTATIVE PROTEIN BINDING, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, UNKNOWN FUNCTION
4oju:C (LYS137) to (GLU164) CRYSTAL STRUCTURE OF A LEUCINE-RICH REPEAT PROTEIN (BACCAP_00569) FROM BACTEROIDES CAPILLOSUS ATCC 29799 AT 2.00 A RESOLUTION | LEUCINE RICH REPEATS,PF13306 FAMILY PROTEIN, PUTATIVE PROTEIN BINDING, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, UNKNOWN FUNCTION
1m06:G (TYR51) to (ALA90) STRUCTURAL STUDIES OF BACTERIOPHAGE ALPHA3 ASSEMBLY, X-RAY CRYSTALLOGRAPHY | BACTERIOPHAGE, THREE-DIMENSIONAL STRUCTURE, VIRION, MORPHOGENESIS, PHIX174, ASSEMBLY, MICROVIRIDAE, ICOSAHEDRAL VIRUS, VIRUS-DNA COMPLEX
1m0b:A (ARG8) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH AN ETHYLENEAMINE INHIBITOR | HIV PROTEASE, PEPTIDOMIMETICS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1m0b:B (ARG108) to (GLU134) HIV-1 PROTEASE IN COMPLEX WITH AN ETHYLENEAMINE INHIBITOR | HIV PROTEASE, PEPTIDOMIMETICS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4okd:A (PHE140) to (GLY174) CRYSTAL STRUCTURE OF CHLAMYDOMONAS REINHARDTII ISOAMYLASE 1 (ISA1) IN COMPLEX WITH MALTOHEPTAOSE | GH13 GLYCOSIDE HYDROLASE, HYDROLASE
2zh9:A (ARG198) to (ASP218) COMPLEX STRUCTURE OF AFCCA WITH TRNAMINIDU | TRANSFERASE/RNA, ATP-BINDING, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RNA REPAIR, RNA- BINDING, TRNA PROCESSING
3kc0:A (CYS92) to (PHE117) CRYSTAL STRUCTURE OF HUMAN LIVER FBPASE IN COMPLEX WITH TRICYCLIC INHIBITOR 10B | HYDROLASE, ALLOSTERIC ENZYME, CARBOHYDRATE METABOLISM, DISEASE MUTATION, GLUCONEOGENESIS, MAGNESIUM, METAL- BINDING, POLYMORPHISM
1m4u:A (THR153) to (CYS192) CRYSTAL STRUCTURE OF BONE MORPHOGENETIC PROTEIN-7 (BMP-7) IN COMPLEX WITH THE SECRETED ANTAGONIST NOGGIN | NOGGIN, BMP ANTAGONIST, BMP-7, BONE MORPHOGENETIC PROTEIN, CYSTINE KNOT, HORMONE-GROWTH FACTOR COMPLEX
1xsj:B (ILE711) to (LEU738) STRUCTURE OF A FAMILY 31 ALPHA GLYCOSIDASE | BETA(8)ALPHA(8) BARREL AND BETA SANDWICH DOMAINS, HYDROLASE
1xsk:A (ILE711) to (LEU738) STRUCTURE OF A FAMILY 31 ALPHA GLYCOSIDASE GLYCOSYL-ENZYME INTERMEDIATE | BETA(8)ALPHA(8) BARREL AND BETA SANDWICH DOMAINS, HYDROLASE
2zle:A (SER18) to (THR65) CRYO-EM STRUCTURE OF DEGP12/OMP | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE, SERINE PROTEASE, STRESS RESPONSE, ION TRANSPORT, PHAGE RECOGNITION, PORIN, TRANSMEMBRANE, TRANSPORT
2zle:B (SER414) to (THR461) CRYO-EM STRUCTURE OF DEGP12/OMP | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE, SERINE PROTEASE, STRESS RESPONSE, ION TRANSPORT, PHAGE RECOGNITION, PORIN, TRANSMEMBRANE, TRANSPORT
2zle:C (SER810) to (THR857) CRYO-EM STRUCTURE OF DEGP12/OMP | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE, SERINE PROTEASE, STRESS RESPONSE, ION TRANSPORT, PHAGE RECOGNITION, PORIN, TRANSMEMBRANE, TRANSPORT
2zle:E (SER1552) to (THR1599) CRYO-EM STRUCTURE OF DEGP12/OMP | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE, SERINE PROTEASE, STRESS RESPONSE, ION TRANSPORT, PHAGE RECOGNITION, PORIN, TRANSMEMBRANE, TRANSPORT
2zle:F (SER1948) to (THR1995) CRYO-EM STRUCTURE OF DEGP12/OMP | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE, SERINE PROTEASE, STRESS RESPONSE, ION TRANSPORT, PHAGE RECOGNITION, PORIN, TRANSMEMBRANE, TRANSPORT
2zle:G (SER2344) to (THR2391) CRYO-EM STRUCTURE OF DEGP12/OMP | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE, SERINE PROTEASE, STRESS RESPONSE, ION TRANSPORT, PHAGE RECOGNITION, PORIN, TRANSMEMBRANE, TRANSPORT
2zle:H (SER2740) to (THR2787) CRYO-EM STRUCTURE OF DEGP12/OMP | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE, SERINE PROTEASE, STRESS RESPONSE, ION TRANSPORT, PHAGE RECOGNITION, PORIN, TRANSMEMBRANE, TRANSPORT
2zle:I (SER3136) to (THR3183) CRYO-EM STRUCTURE OF DEGP12/OMP | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE, SERINE PROTEASE, STRESS RESPONSE, ION TRANSPORT, PHAGE RECOGNITION, PORIN, TRANSMEMBRANE, TRANSPORT
2zle:J (SER3532) to (THR3579) CRYO-EM STRUCTURE OF DEGP12/OMP | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE, SERINE PROTEASE, STRESS RESPONSE, ION TRANSPORT, PHAGE RECOGNITION, PORIN, TRANSMEMBRANE, TRANSPORT
2zle:K (SER3928) to (THR3975) CRYO-EM STRUCTURE OF DEGP12/OMP | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE, SERINE PROTEASE, STRESS RESPONSE, ION TRANSPORT, PHAGE RECOGNITION, PORIN, TRANSMEMBRANE, TRANSPORT
2zle:L (SER4324) to (THR4371) CRYO-EM STRUCTURE OF DEGP12/OMP | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE, SERINE PROTEASE, STRESS RESPONSE, ION TRANSPORT, PHAGE RECOGNITION, PORIN, TRANSMEMBRANE, TRANSPORT
2zle:M (SER4720) to (THR4767) CRYO-EM STRUCTURE OF DEGP12/OMP | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE, SERINE PROTEASE, STRESS RESPONSE, ION TRANSPORT, PHAGE RECOGNITION, PORIN, TRANSMEMBRANE, TRANSPORT
2ztb:A (GLY87) to (ASN122) CRYSTAL STRUCTURE OF THE PARASPORIN-2 BACILLUS THURINGIENSIS TOXIN THAT RECOGNIZES CANCER CELLS | BETA-HAIRPIN, TOXIN
1mec:2 (VAL14) to (GLY35) CONFORMATIONAL VARIABILITY OF A PICORNAVIRUS CAPSID: PH- DEPENDENT STRUCTURAL CHANGES OF MENGO VIRUS RELATED TO ITS HOST RECEPTOR ATTACHMENT SITE AND DISASSEMBLY | CARDIO PICORNAVIRUS COAT PROTEIN, ICOSAHEDRAL VIRUS
2zvd:C (THR590) to (ALA617) CRYSTAL STRUCTURE OF PSEUDOMONAS SP. MIS38 LIPASE IN AN OPEN CONFORMATION | FAMILY I.3 LIPASE, BETA ROLL, CALCIUM BINDING PROTEIN, RTX PROTEIN, HYDROLASE
4aed:B (VAL13) to (GLY34) CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 | VIRUS, PICORNAVIRUS, CAPSID, PATHOGEN
5d3d:B (LYS226) to (SER259) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN 3 | SUPERANTIGENS, SUPERANTIGEN-LIKE PROTEINS, SSL, SSL3, TOLL-LIKE RECEPTOR 2, TLR2, IMMUNOLOGY, INFLAMMATION, INHIBITION, IMMUNE SYSTEM
5d3i:B (LYS226) to (SER259) CRYSTAL STRUCTURE OF THE SSL3-TLR2 COMPLEX | SUPERANTIGENS, SUPERANTIGEN-LIKE PROTEINS, SSL, SSL3, TOLL-LIKE RECEPTOR 2, TLR2, TLR6, IMMUNOLOGY, INFLAMMATION, INHIBITION, LIPOPEPTIDE, PHOSPHATIDYLCHOLINE, PC, IMMUNE EVASION, INNATE IMMUNITY, IMMUNE SYSTEM
3kmt:B (LEU51) to (LEU80) CRYSTAL STRUCTURE OF VSET/SAH/H3 TERNARY COMPLEX | SET DOMAIN, TERNARY COMPLEX, VIRAL PROTEIN
4p4e:A (TYR127) to (GLY172) X-RAY STRUCTURE OF HUMAN GLUTAMATE CARBOXYPEPTIDASE II (GCPII) IN COMPLEX WITH A PHOSPHORAMIDATE INHIBITOR MP1D | GLUTAMATE CARBOXYPEPTIDASE II (GCPII); NAALADASE; PROSTATE-SPECIFIC MEMBRANE ANTIGEN; PHOSPHORAMIDATE, HYDROLASE
3kpt:B (GLU200) to (GLU223) CRYSTAL STRUCTURE OF BCPA, THE MAJOR PILIN SUBUNIT OF BACILLUS CEREUS | INTRAMOLECULAR AMIDE BOND, PILIN SUBUNIT, BETA SHEET
4p7u:A (ILE99) to (SER127) EXTRACELLULAR DOMAIN OF TYPE II TRANSFORMING GROWTH FACTOR BETA RECEPTOR IN COMPLEX WITH NDSB-201 | NDSB-201, TYPE II TRANSFORMING GROWTH FACTOR BETA RECEPTOR, SIGNALING PROTEIN
1mtb:A (VAL11) to (GLU34) VIABILITY OF A DRUG-RESISTANT HIV-1 PROTEASE MUTANT: STRUCTURAL INSIGHTS FOR BETTER ANTIVIRAL THERAPY | HIV-1 PROTEASE, DRUG RESISTANCE, SUBSTRATE RECOGNITION, INHIBITOR BINDING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1yge:A (ASP61) to (MET103) LIPOXYGENASE-1 (SOYBEAN) AT 100K | DIOXYGENASE, LIPOXYGENASE, METALLOPROTEIN, FATTY ACIDS
4ak2:A (LEU639) to (THR676) STRUCTURE OF BT4661, A SUSE-LIKE SURFACE LOCATED POLYSACCHARIDE BINDING PROTEIN FROM THE BACTEROIDES THETAIOTAOMICRON HEPARIN UTILISATION LOCUS | HEPARIN-BINDING PROTEIN, HEPARAN SULPHATE
4ak1:A (LEU639) to (THR676) STRUCTURE OF BT4661, A SUSE-LIKE SURFACE LOCATED POLYSACCHARIDE BINDING PROTEIN FROM THE BACTEROIDES THETAIOTAOMICRON HEPARIN UTILISATION LOCUS | HEPARIN-BINDING PROTEIN, HEPARAN SULPHATE
4pch:A (GLN35) to (ALA110) STRUCTURE OF HUMAN POLYOMAVIRUS 7 (HPYV7) VP1 PENTAMER | MAJOR VIRAL CAPSID PROTEIN, JELLY-ROLL TOPOLOGY, ATTACHMENT TO HOST- CELL RECEPTORS, VIRAL PROTEIN
4pch:E (GLN35) to (ARG102) STRUCTURE OF HUMAN POLYOMAVIRUS 7 (HPYV7) VP1 PENTAMER | MAJOR VIRAL CAPSID PROTEIN, JELLY-ROLL TOPOLOGY, ATTACHMENT TO HOST- CELL RECEPTORS, VIRAL PROTEIN
1yiq:A (TRP453) to (ALA485) MOLECULAR CLONING AND STRUCTURAL ANALYSIS OF QUINOHEMOPROTEIN ALCOHOL DEHYDROGENASE ADHIIG FROM PSEUDOMONAS PUTIDA HK5. COMPARIISON TO THE OTHER QUINOHEMOPROTEIN ALCOHOL DEHYDROGENASE ADHIIB FOUND IN THE SAME MICROORGANISM. | QUINOHEMOPROTEIN ALCOHOL DEHYDROGENASE, ELECTRON TRANSFER, OXIDOREDUCTASE
3a7b:A (THR65) to (GLU92) CRYSTAL STRUCTURE OF TLR2-STREPTOCOCCUS PNEUMONIAE LIPOTEICHOIC ACID COMPLEX | TOLL-LIKE RECEPTOR, LIPOTEICHOIC ACID, LEUCINE RICH REPEAT, CELL MEMBRANE, CYTOPLASMIC VESICLE, DISULFIDE BOND, GLYCOPROTEIN, IMMUNE RESPONSE, INFLAMMATORY RESPONSE, MEMBRANE, RECEPTOR, TRANSMEMBRANE, PHOSPHOPROTEIN, IMMUNE SYSTEM
3kv4:A (GLN232) to (LYS261) STRUCTURE OF PHF8 IN COMPLEX WITH HISTONE H3 | EPIGENETICS, HISTONE CODE, COVALENT HISTONE MODIFICATIONS, JUMONJI DEMETHYLASE, MENTAL RETARDATION, METAL-BINDING, ZINC, ZINC-FINGER
3abz:B (ILE414) to (PHE445) CRYSTAL STRUCTURE OF SE-MET LABELED BETA-GLUCOSIDASE FROM KLUYVEROMYCES MARXIANUS | GLYCOSIDE HYDROLASE FAMILY3 BETA-GLUCOSIDASE, PA14 DOMAIN, HYDROLASE
1yt9:B (VAL11) to (GLU34) HIV PROTEASE WITH OXIMINOARYLSULFONAMIDE BOUND | HIV PROTEASE, OXIMINOARYLSULFONAMIDES, HYDROLASE
3l5l:A (GLU6) to (TYR27) XENOBIOTIC REDUCTASE A - OXIDIZED | TIM BARREL, OXIDOREDUCTASE
1ywh:A (ASN52) to (GLY99) CRYSTAL STRUCTURE OF UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR | UPAR, THREE-FINGER FOLD, PROTEIN-PEPTIDE COMPLEX, HYDROLASE RECEPTOR
1ywh:G (THR51) to (GLY99) CRYSTAL STRUCTURE OF UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR | UPAR, THREE-FINGER FOLD, PROTEIN-PEPTIDE COMPLEX, HYDROLASE RECEPTOR
1ywh:K (THR51) to (GLY99) CRYSTAL STRUCTURE OF UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR | UPAR, THREE-FINGER FOLD, PROTEIN-PEPTIDE COMPLEX, HYDROLASE RECEPTOR
3l68:A (GLU6) to (TYR27) XENOBIOTIC REDUCTASE A - C25S VARIANT WITH COUMARIN | FMN, TIM BARREL, OXIDOREDUCTASE
1yz0:A (CYS92) to (PHE117) R-STATE AMP COMPLEX REVEALS INITIAL STEPS OF THE QUATERNARY TRANSITION OF FRUCTOSE-1,6-BISPHOSPHATASE | ALLOSTERIC ENZYMES; INTERMEDIATE STATES; GLYCOLYSIS; GLUCONEOGENESIS, HYDROLASE
4pm3:B (PHE41) to (THR65) STRUCTURE OF THE DOUBLE-STRANDED DNA BINDING TYPE IV SECRETION PROTEIN TRAN FROM ENTEROCOCCUS | TYPE IV SECRETION, INTERNAL DIMER, ISOMERASE, DNA BINDING PROTEIN
3l81:A (PHE296) to (LEU328) CRYSTAL STRUCTURE OF ADAPTOR PROTEIN COMPLEX 4 (AP-4) MU4 SUBUNIT C- TERMINAL DOMAIN, IN COMPLEX WITH A SORTING PEPTIDE FROM THE AMYLOID PRECURSOR PROTEIN (APP) | IMMUNOGLOBULIN-LIKE BETA-SANDWICH, COATED PIT, GOLGI APPARATUS, MEMBRANE, PHOSPHOPROTEIN, PROTEIN TRANSPORT, TRANSPORT, ALZHEIMER DISEASE, AMYLOID, AMYLOIDOSIS, TRANSPORT PROTEIN
1z42:A (THR7) to (TYR28) CRYSTAL STRUCTURE OF OXIDIZED YQJM FROM BACILLUS SUBTILIS COMPLEXED WITH P-HYDROXYBENZALDEHYDE | FLAVIN, FMN, P-HYDROXYBENZALDEHYDE, BETA-ALPHA-BARREL, OXIDOREDUCTASE
1z42:B (THR7) to (TYR28) CRYSTAL STRUCTURE OF OXIDIZED YQJM FROM BACILLUS SUBTILIS COMPLEXED WITH P-HYDROXYBENZALDEHYDE | FLAVIN, FMN, P-HYDROXYBENZALDEHYDE, BETA-ALPHA-BARREL, OXIDOREDUCTASE
4alf:B (TRP248) to (ASN274) PSEUDOMONAS FLUORESCENS PHOX IN COMPLEX WITH PHOSPHATE | HYDROLASE, BETA-PROPELLER
3laq:U (ASN52) to (THR100) STRUCTURE-BASED ENGINEERING OF SPECIES SELECTIVITY IN THE UPA-UPAR INTERACTION | UPA, UPAR, ATF, SUPAR, SMUPAR, MATF, DISULFIDE BOND, EGF-LIKE DOMAIN, HYDROLASE, KRINGLE, PLASMINOGEN ACTIVATION, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, CELL MEMBRANE, GLYCOPROTEIN, GPI-ANCHOR, LIPOPROTEIN, MEMBRANE, RECEPTOR, HYDROLASE-HYDROLASE RECEPTOR COMPLEX
3laq:U (PRO152) to (GLY197) STRUCTURE-BASED ENGINEERING OF SPECIES SELECTIVITY IN THE UPA-UPAR INTERACTION | UPA, UPAR, ATF, SUPAR, SMUPAR, MATF, DISULFIDE BOND, EGF-LIKE DOMAIN, HYDROLASE, KRINGLE, PLASMINOGEN ACTIVATION, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, CELL MEMBRANE, GLYCOPROTEIN, GPI-ANCHOR, LIPOPROTEIN, MEMBRANE, RECEPTOR, HYDROLASE-HYDROLASE RECEPTOR COMPLEX
3laq:V (GLY153) to (GLY197) STRUCTURE-BASED ENGINEERING OF SPECIES SELECTIVITY IN THE UPA-UPAR INTERACTION | UPA, UPAR, ATF, SUPAR, SMUPAR, MATF, DISULFIDE BOND, EGF-LIKE DOMAIN, HYDROLASE, KRINGLE, PLASMINOGEN ACTIVATION, PROTEASE, SECRETED, SERINE PROTEASE, ZYMOGEN, CELL MEMBRANE, GLYCOPROTEIN, GPI-ANCHOR, LIPOPROTEIN, MEMBRANE, RECEPTOR, HYDROLASE-HYDROLASE RECEPTOR COMPLEX
4amv:A (GLY209) to (GLU235) E.COLI GLUCOSAMINE-6P SYNTHASE IN COMPLEX WITH FRUCTOSE-6P | TRANSFERASE, AMMONIA CHANNELING, GLUCOSAMINE 6- PHOSPHATE SYNTHASE, N TERMINAL NUCLEOPHILE, GLUTAMINE AMIDOTRANSFERASE
3lei:A (VAL83) to (GLY115) LECTIN DOMAIN OF LECTINOLYSIN COMPLEXED WITH FUCOSE | LECTIN DOMAIN OF LECTINOLYSIN, FUCOSE, BLOOD CLOTTING, NICKEL
1z7s:2 (VAL13) to (ALA34) THE CRYSTAL STRUCTURE OF COXSACKIEVIRUS A21 | PICORNAVIRUS, COXSACKIEVIRUS, A21, CAPSID PROTEIN, VIRAL PROTEIN, ICOSAHEDRAL VIRUS
3lfb:A (THR7) to (GLY31) HUMAN P38 MAP KINASE IN COMPLEX WITH RL98 | THIAZOLE-UREA, DFG-OUT, SAR, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
1z9s:C (ASN80) to (VAL146) CRYSTAL STRUCTURE OF THE NATIVE CHAPERONE:SUBUNIT:SUBUNIT CAF1M:CAF1:CAF1 COMPLEX | DONOR STRAND COMPLEMENTATION, NATIVE MINIMAL FIBER, CHAPERONE-USHER PATHWAY, CHAPERONE/IMMUNE SYSTEM COMPLEX
3lhj:A (THR7) to (GLY31) CRYSTAL STRUCTURE OF P38A MITOGEN-ACTIVATED PROTEIN KINASE IN COMPLEX WITH A PYRAZOLOPYRIDINONE INHIBITOR. | SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM
5du8:B (MET1) to (SER26) CRYSTAL STRUCTURE OF M. TUBERCULOSIS ECHA6 BOUND TO GSK572A | LYASE, ENOYL-COA HYDRATASE-LIKE, LIPID BINDING PROTEIN
1zgr:B (SER393) to (ILE416) CRYSTAL STRUCTURE OF THE PARKIA PLATYCEPHALA SEED LECTIN | BETA-PRISM, LECTIN, SUGAR BINDING PROTEIN
3lkw:A (GLU143) to (ALA177) CRYSTAL STRUCTURE OF DENGUE VIRUS 1 NS2B/NS3 PROTEASE ACTIVE SITE MUTANT | VIRAL PROTEASE, SERINE PROTEASE, NS3 PROTEASE, NS2B COFACTOR, VIRAL PROTEIN, HYDROLASE
1zj7:A (ARG8) to (GLU34) CRYSTAL STRUCTURE OF A COMPLEX OF MUTANT HIV-1 PROTEASE (A71V, V82T, I84V) WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR BOC-PHE- PSI[S-CH(OH)CH2NH]-PHE-GLU-PHE-NH2 | HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1zlf:A (ARG8) to (GLU34) CRYSTAL STRUCTURE OF A COMPLEX OF MUTANT HIV-1 PROTEASE (A71V, V82T, I84V) WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR | HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1zlf:B (PRO109) to (GLU134) CRYSTAL STRUCTURE OF A COMPLEX OF MUTANT HIV-1 PROTEASE (A71V, V82T, I84V) WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR | HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4q1w:A (VAL11) to (GLU34) MUTATIONS OUTSIDE THE ACTIVE SITE OF HIV-1 PROTEASE ALTER ENZYME STRUCTURE AND DYNAMIC ENSEMBLE OF THE ACTIVE SITE TO CONFER DRUG RESISTANCE | HIV-1 PROTEASE, AIDS, INHIBITOR COMPLEX, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4q1x:B (VAL11) to (GLU34) MUTATIONS OUTSIDE THE ACTIVE SITE OF HIV-1 PROTEASE ALTER ENZYME STRUCTURE AND DYNAMIC ENSEMBLE OF THE ACTIVE SITE TO CONFER DRUG RESISTANCE | HIV-1 PROTEASE, AIDS, INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4atz:A (ASP422) to (ASP466) AD5 KNOB IN COMPLEX WITH A DESIGNED ANKYRIN REPEAT PROTEIN | VIRAL PROTEIN-DE NOVO PROTEIN COMPLEX, DARPIN, PROTEIN DESIGN
4atz:B (ALA419) to (ASP462) AD5 KNOB IN COMPLEX WITH A DESIGNED ANKYRIN REPEAT PROTEIN | VIRAL PROTEIN-DE NOVO PROTEIN COMPLEX, DARPIN, PROTEIN DESIGN
4atz:C (ASP418) to (ASP462) AD5 KNOB IN COMPLEX WITH A DESIGNED ANKYRIN REPEAT PROTEIN | VIRAL PROTEIN-DE NOVO PROTEIN COMPLEX, DARPIN, PROTEIN DESIGN
1zsf:B (VAL111) to (GLU134) CRYSTAL STRUCTURE OF COMPLEX OF A HYDROXYETHYLAMINE INHIBITOR WITH HIV-1 PROTEASE AT 2.0A RESOLUTION | HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ltf:A (PHE497) to (CYS524) CRYSTAL STRUCTURE OF THE DROSOPHILA EPIDERMAL GROWTH FACTOR RECEPTOR ECTODOMAIN IN COMPLEX WITH SPITZ | RECEPTOR-LIGAND COMPLEX ECTODOMAIN CYSTEINE RICH DOMAIN EGF DOMAIN, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, RECEPTOR, TRANSFERASE, TYROSINE-PROTEIN KINASE, CELL MEMBRANE, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, DISULFIDE BOND, EGF-LIKE DOMAIN, ENDOPLASMIC RETICULUM, GLYCOPROTEIN, GOLGI APPARATUS, MEMBRANE, NEUROGENESIS, TRANSMEMBRANE, TRANSFERASE-TRANSFERASE REGULATOR COMPLEX
3ltg:A (PHE497) to (ILE523) CRYSTAL STRUCTURE OF THE DROSOPHILA EPIDERMAL GROWTH FACTOR RECEPTOR ECTODOMAIN COMPLEXED WITH A LOW AFFINITY SPITZ MUTANT | RECEPTOR-LIGAND COMPLEX ECTODOMAIN CYSTEINE RICH DOMAIN EGF DOMAIN, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, RECEPTOR, TRANSFERASE, TYROSINE-PROTEIN KINASE, CELL MEMBRANE, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, DISULFIDE BOND, EGF-LIKE DOMAIN, ENDOPLASMIC RETICULUM, GLYCOPROTEIN, GOLGI APPARATUS, MEMBRANE, NEUROGENESIS, TRANSMEMBRANE, TRANSFERASE-TRANSFERASE REGULATOR COMPLEX
4aws:A (GLN7) to (SER28) CRYSTAL STRUCTURE OF THE OXIDIZED SHEWANELLA YELLOW ENZYME 1 (SYE1) M25L MUTANT | OXIDOREDUCTASE, COFACTOR-BINDING
4awt:A (GLN7) to (SER28) CRYSTAL STRUCTURE OF THE REDUCED SHEWANELLA YELLOW ENZYME 1 (SYE1) M25L MUTANT | OXIDOREDUCTASE, COFACTOR-BINDING
5e51:D (LEU125) to (GLY153) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 1 WITH FAROPENEM ADDUCT | L, D-TRANSPEPTIDASE 1, PEPTIDOGLYCAN SYNTHESIS ENZYME, CELL WALL ENZYME, LDTMT1, MYCOBACTERIUM TUBERCULOSIS, TRANSFERASE
5e6j:D (ALA182) to (GLY210) STRUCTURE OF SARS PLPRO BOUND TO A LYS48-LINKED DI-UBIQUITIN ACTIVITY BASED PROBE | SARS PLPRO, DEUBIQUITINATING ENZYME, UBIQUITIN, ACTIVITY BASED PROBE, K48-LINKAGE, HYDROLASE
3at0:A (VAL219) to (PRO262) STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF CLFB:LIGAND INTERACTIONS | IGG LIKE, ADHESIN, FIBRINOGEN, CYTOKERATIN, CELL ADHESION-BLOOD CLOTTING COMPLEX
3au0:A (VAL219) to (PRO262) STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF CLFB:LIGAND INTERACTIONS | IGG-LIKE, ADHESIN, CYTOKERATIN, FIBRINOGEN, CELL ADHESION
5e70:D (HIS164) to (MET192) CRYSTAL STRUCTURE OF ECOLI BRANCHING ENZYME WITH GAMMA CYCLODEXTRIN | BRANCHING ENZYME, CYCLODEXTRIN, GLYCOGEN, STARCH, GLUCAN, TRANSFERASE
3lzv:A (VAL11) to (GLU34) STRUCTURE OF NELFINAVIR-RESISTANT HIV-1 PROTEASE (D30N/N88D) IN COMPLEX WITH DARUNAVIR. | HIV-1 PROTEASE, RESISTANCE, HYDROLASE
3lzv:B (VAL11) to (GLU34) STRUCTURE OF NELFINAVIR-RESISTANT HIV-1 PROTEASE (D30N/N88D) IN COMPLEX WITH DARUNAVIR. | HIV-1 PROTEASE, RESISTANCE, HYDROLASE
2a4f:B (VAL11) to (GLU34) SYNTHESIS AND ACTIVITY OF N-AXYL AZACYCLIC UREA HIV-1 PROTEASE INHIBITORS WITH HIGH POTENCY AGAINST MULTIPLE DRUG RESISTANT VIRAL STRAINS. | HIV PROTEASE, AZA-CYCLIC UREA, HYDROLASE
4qar:A (THR89) to (ARG121) 1.45 A RESOLUTION STRUCTURE OF CT263 (MTAN) FROM CHLAMYDIA TRACHOMATIS BOUND TO ADENINE | CHLAMYDIA, QUINONES, NUCLEOSIDASE, FUTALOSINE PATHWAY, PRODUCT-BOUND, HYDROLASE
4qat:A (THR89) to (ARG121) 1.75 A RESOLUTION STRUCTURE OF CT263-D161N (MTAN) FROM CHLAMYDIA TRACHOMATIS BOUND TO MTA | CHLAMYDIA, QUINONES, NUCLEOSIDASE, FUTALOSINE PATHWAY, SUBSTRATE- BOUND, HYDROLASE
4qaw:E (SER481) to (GLY516) STRUCTURE OF MODULAR XYN30D FROM PAENIBACILLUS BARCINONENSIS | TIM BARREL, BETA-STRUCTURE, HYDROLASE, CARBOHYDRATE/SUGAR BINDING, CALCIUM BINDING, TIM BARREL BETA-STRUCTURE, CARBOHYDRATE/SUGAR BINDING CALCIUM BINDING, PLANT-CELL WALL DEGRADATION
3m1c:A (ILE684) to (PRO715) CRYSTAL STRUCTURE OF THE CONSERVED HERPESVIRUS FUSION REGULATOR COMPLEX GH-GL | GLYCOPROTEIN H, GLYCOPROTEIN L, GH/GL, ENVELOPE PROTEIN, HERPES SIMPLEX VIRUS, DISULFIDE BOND, GLYCOPROTEIN, HOST CELL MEMBRANE, HOST ENDOSOME, HOST MEMBRANE, MEMBRANE, TRANSMEMBRANE, VIRION, VIRUS REFERENCE STRAIN, VIRAL PROTEIN
3m53:A (LEU169) to (PHE193) SET7/9 IN COMPLEX WITH TAF10 PEPTIDE AND ADOHCY | TERNARY COMPLEX, SET DOMAIN, METHYLTRANSFERASE, S-ADENOSYL-L- HOMOCYSTEINE, TAF10 PEPTIDE, CHROMATIN REGULATOR, CHROMOSOMAL PROTEIN, NUCLEUS, S-ADENOSYL-L-METHIONINE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE
3m54:A (LEU169) to (PHE193) SET7/9 Y305F IN COMPLEX WITH TAF10 PEPTIDE AND ADOHCY | TERNARY COMPLEX, SET DOMAIN, METHYLTRANSFERASE, S-ADENOSYL-L- HOMOCYSTEINE, TAF10 PEPTIDE, CHROMATIN REGULATOR, CHROMOSOMAL PROTEIN, NUCLEUS, S-ADENOSYL-L-METHIONINE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE
3m55:A (LEU169) to (PHE193) SET7/9 Y305F IN COMPLEX WITH TAF10-K189ME1 PEPTIDE AND ADOHCY | TERNARY COMPLEX, SET DOMAIN, METHYLTRANSFERASE, S-ADENOSYL-L- HOMOCYSTEINE, TAF10 PEPTIDE, N-MONOMETHYLLYSINE, CHROMATIN REGULATOR, CHROMOSOMAL PROTEIN, NUCLEUS, S-ADENOSYL-L-METHIONINE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE
3m57:A (LEU169) to (PHE193) SET7/9 Y245A IN COMPLEX WITH TAF10 PEPTIDE AND ADOHCY | TERNARY COMPLEX, SET DOMAIN, METHYLTRANSFERASE, S-ADENOSYL-L- HOMOCYSTEINE, TAF10 PEPTIDE, CHROMATIN REGULATOR, CHROMOSOMAL PROTEIN, NUCLEUS, S-ADENOSYL-L-METHIONINE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE
3m58:A (LEU169) to (PHE193) SET7/9 Y245A IN COMPLEX WITH TAF10-K189ME1 PEPTIDE AND ADOHCY | TERNARY COMPLEX, SET DOMAIN, METHYLTRANSFERASE, S-ADENOSYL-L- HOMOCYSTEINE, TAF10 PEPTIDE, N-MONOMETHYLLYSINE, CHROMATIN REGULATOR, CHROMOSOMAL PROTEIN, S-ADENOSYL-L-METHIONINE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE
3m59:A (LEU169) to (PHE193) SET7/9 Y245A IN COMPLEX WITH TAF10-K189ME2 PEPTIDE AND ADOHCY | TERNARY COMPLEX, SET DOMAIN, METHYLTRANSFERASE, S-ADENOSYL-L- HOMOCYSTEINE, TAF10 PEPTIDE, N-DIMETHYLLYSINE, CHROMATIN REGULATOR, CHROMOSOMAL PROTEIN, NUCLEUS, S-ADENOSYL-L-METHIONINE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE
3m5a:A (LEU169) to (PHE193) SET7/9 Y245A IN COMPLEX WITH TAF10-K189ME3 PEPTIDE AND ADOHCY | TERNARY COMPLEX, SET DOMAIN, METHYLTRANSFERASE, S-ADENOSYL-L- HOMOCYSTEINE, TAF10 PEPTIDE, N-TRIMETHYLLYSINE, CHROMATIN REGULATOR, CHROMOSOMAL PROTEIN, NUCLEUS, S-ADENOSYL-L-METHIONINE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE
4qgi:B (THR12) to (GLU34) X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE VARIANT G48T/L89M IN COMPLEX WITH SAQUINAVIR | SAQUINAVIR, HIV PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3b2d:B (THR485) to (GLN514) CRYSTAL STRUCTURE OF HUMAN RP105/MD-1 COMPLEX | PROTEIN-PROTEIN COMPLEX, LEUCINE RICH REPEAT MD-2 RELATED LIPID RECOGNITION, RECEPTOR INNATE IMMUNITY, GLYCOSYLATION, IMMUNE SYSTEM
5eg2:A (LEU169) to (PHE193) SET7/9 N265A IN COMPLEX WITH ADOHCY AND TAF10 PEPTIDE | TRANSFERASE-TRANSCRIPTION FACTOR COMPLEX
3m9f:A (VAL11) to (GLU34) HIV PROTEASE COMPLEXED WITH COMPOUND 10B | HIV, PROTEASE, TRANSFERASE
3m9f:B (VAL11) to (GLU34) HIV PROTEASE COMPLEXED WITH COMPOUND 10B | HIV, PROTEASE, TRANSFERASE
4qj6:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (L449F) | CO-EVOLUTION, PROTEASE, HYDROLASE
4qj6:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (L449F) | CO-EVOLUTION, PROTEASE, HYDROLASE
4qj6:C (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (L449F) | CO-EVOLUTION, PROTEASE, HYDROLASE
4qj6:D (ARG8) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (L449F) | CO-EVOLUTION, PROTEASE, HYDROLASE
4qj7:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (R452S) | CO-EVOLUTION, PROTEASE, HYDROLASE
4qj7:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (R452S) | CO-EVOLUTION, PROTEASE, HYDROLASE
4qj8:B (ARG8) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (P453L) | CO-EVOLUTION, PROTEASE, HYDROLASE
4qj8:C (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (P453L) | CO-EVOLUTION, PROTEASE, HYDROLASE
4qj9:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (R452S) | CO-EVOLUTION, PROTEASE, HYDROLASE
4qja:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (P453L) | CO-EVOLUTION, PROTEASE, HYDROLASE
3mdj:C (LEU74) to (SER103) ER AMINOPEPTIDASE, ERAP1, BOUND TO THE ZINC AMINOPEPTIDASE INHIBITOR, BESTATIN | AMINOPEPTIDASE, ZN BINDING PROTEIN, ER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2afj:A (ILE57) to (ARG82) SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 2 (SSB-2) | BETA SANDWICH, GENE REGULATION
3b8w:D (GLU251) to (ALA271) CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221P | ALPHA/BETA BARREL, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, ISOMERASE, PEPTIDOGLYCAN SYNTHESIS, PYRIDOXAL PHOSPHATE
3mga:A (PRO66) to (GLU98) 2.4 ANGSTROM CRYSTAL STRUCTURE OF FERRIC ENTEROBACTIN ESTERASE (FES) FROM SALMONELLA TYPHIMURIUM | CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, FERRIC ENTEROBACTIN ESTERASE, HYDROLASE
3mga:B (PRO66) to (PRO96) 2.4 ANGSTROM CRYSTAL STRUCTURE OF FERRIC ENTEROBACTIN ESTERASE (FES) FROM SALMONELLA TYPHIMURIUM | CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, FERRIC ENTEROBACTIN ESTERASE, HYDROLASE
3mh4:B (SER28) to (THR102) HTRA PROTEASES ARE ACTIVATED BY A CONSERVED MECHANISM THAT CAN BE TRIGGERED BY DISTINCT MOLECULAR CUES | DEGP, HTRA, PROTEASE, HYDROLASE
3bgb:B (VAL11) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH A ISOBUTYL DECORATED OLIGOAMINE | PROTEIN-LIGAND COMPLEX, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER
5eta:A (THR7) to (PRO29) STRUCTURE OF MAPK14 WITH BOUND THE KIM DOMAIN OF THE TOXOPLASMA PROTEIN GRA24 | MAPK14, GRA24, KIM DOMAIN, PEPTIDE-PROTEIN COMPLEX, TRANSFERASE
4qtb:B (GLU27) to (ALA52) STRUCTURE OF HUMAN ERK1 IN COMPLEX WITH SCH772984 REVEALING A NOVEL INHIBITOR-INDUCED BINDING POCKET | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE, KINASE, MAPK, SIGNALLING, INHIBITOR, ALLOSTERIC, STRUCTURAL GENOMICS CONSORTIUM (SGC), TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4bkw:A (ASP1170) to (SER1201) CRYSTAL STRUCTURE OF THE C-TERMINAL REGION OF HUMAN ZFYVE9 | RECEPTOR, PROTEIN INTERACTION DOMAIN, TGF-BETA AND EGFR SIGNALLING, SGC
3mt1:A (SER285) to (GLN319) CRYSTAL STRUCTURE OF PUTATIVE CARBOXYNORSPERMIDINE DECARBOXYLASE PROTEIN FROM SINORHIZOBIUM MELILOTI | PSI2, MCSG, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, CARBOXYNORSPERMIDINE DECARBOXYLASE, LYASE
3muy:4 (PHE626) to (VAL656) E. COLI (LACZ) BETA-GALACTOSIDASE (R599A) | ARG-599-ALA, BETA-GALACTOSIDASE, HYDROLASE, TIM BARREL(ALPHA/BETA BARREL), JELLY-ROLL BARREL, IMMUNOGLOBULIN BETA SUPERSANDWHICH, GLYCOSIDASE
3mv0:1 (PHE626) to (ALA657) E. COLI (LACZ) BETA-GALACTOSIDASE (R599A) IN COMPLEX WITH D- GALCTOPYRANOSYL-1-ONE | ARG-599-ALA, BETA-GALACTOSIDASE, HYDROLASE TIM BARREL(ALPHA/BETA BARREL), JELLY-ROLL BARREL, IMMUNOGLOBULIN BETA SUPERSANDWHICH, GLYCOSIDASE, HYDROLASE
3mv0:4 (PHE626) to (ALA657) E. COLI (LACZ) BETA-GALACTOSIDASE (R599A) IN COMPLEX WITH D- GALCTOPYRANOSYL-1-ONE | ARG-599-ALA, BETA-GALACTOSIDASE, HYDROLASE TIM BARREL(ALPHA/BETA BARREL), JELLY-ROLL BARREL, IMMUNOGLOBULIN BETA SUPERSANDWHICH, GLYCOSIDASE, HYDROLASE
3brd:A (GLU285) to (ALA327) CSL (LAG-1) BOUND TO DNA WITH LIN-12 RAM PEPTIDE, P212121 | PROTEIN-DNA COMPLEX, SIGNALING, TRANSCRIPTION, NOTCH, DNA- BINDING, ANK REPEAT, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, EGF-LIKE DOMAIN, GLYCOPROTEIN, MEMBRANE, TRANSMEMBRANE, DNA BINDING PROTEIN/DNA COMPLEX
3mvl:B (THR7) to (GLY31) P38 ALPHA MAP KINASE COMPLEXED WITH PYRROLOTRIAZINE INHIBITOR 7K | SERINE/THREONINE-PROTEIN KINASE, KINASE, TRANSFERASE, P38 MAP KINASE
4bpa:B (HIS63) to (VAL108) CRYSTAL STRUCTURE OF AMPDH2 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH NAG-NAM-NAG-NAM TETRASACCHARIDE | HYDROLASE
3bt2:U (SER156) to (GLY199) STRUCTURE OF UROKINASE RECEPTOR, UROKINASE AND VITRONECTIN COMPLEX | PROTEIN-PROTEIN INTERACTION, GLYCOPROTEIN, GPI-ANCHOR, LIPOPROTEIN, MEMBRANE, RECEPTOR, SECRETED, BLOOD COAGULATION, EGF-LIKE DOMAIN, FIBRINOLYSIS, HYDROLASE, KRINGLE, PHOSPHOPROTEIN, PLASMINOGEN ACTIVATION, PROTEASE, SERINE PROTEASE, ZYMOGEN, CELL ADHESION, HEPARIN-BINDING, SULFATION, IMMUNOGLOBULIN DOMAIN, IMMUNE SYSTEM
3mx0:A (VAL383) to (GLY417) CRYSTAL STRUCTURE OF EPHA2 ECTODOMAIN IN COMPLEX WITH EPHRIN-A5 | ECTODOMAIN, RECEPTOR-LIGAND COMPLEX, RECEPTOR-RECEPTOR INTERACTION, TRANSFERASE RECEPTOR-SIGNALLING PROTEIN COMPLEX
3mxe:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE INHIBITOR, KC32 COMPLEXED WITH WILD-TYPE PROTEASE | DRUG DESIGN, PROTEASE INHIBITORS, HIV PROTEASE, HYDROLASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3mxe:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE INHIBITOR, KC32 COMPLEXED WITH WILD-TYPE PROTEASE | DRUG DESIGN, PROTEASE INHIBITORS, HIV PROTEASE, HYDROLASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3bvb:B (VAL11) to (GLU34) CYSTAL STRUCTURE OF HIV-1 ACTIVE SITE MUTANT D25N AND INHIBITOR DARUNAVIR | DRUG RESISTANCE; HIV-1; D25N, MUTANT, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, DNA INTEGRATION, DNA RECOMBINATION, DNA- DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC-FINGER
3n14:A (GLU6) to (TYR27) XENA - W358A | FLAVIN, OXIDOREDUCTASE, FMN, QUINOLINE
3n19:B (GLU6) to (TYR27) XENA - REDUCED | FMN, FLAVIN, OXIDOREDUCTASE
3n19:D (GLU6) to (TYR27) XENA - REDUCED | FMN, FLAVIN, OXIDOREDUCTASE
3n25:G (ILE180) to (SER204) THE STRUCTURE OF MUSCLE PYRUVATE KINASE IN COMPLEX WITH PROLINE, PYRUVATE, AND MN2+ | PYRUVATE KINASE, GLYCOLYSIS, ALLOSTERIC REGULATION, TRANSFERASE
3n23:A (GLY203) to (GLY249) CRYSTAL STRUCTURE OF THE HIGH AFFINITY COMPLEX BETWEEN OUABAIN AND THE E2P FORM OF THE SODIUM-POTASSIUM PUMP | SODIUM-POTASSIUM PUMP, P-TYPE ATPASE, OUABAIN, CARDIOTONIC STEROIDS, HYDROLASE
3n2c:L (THR2) to (ILE48) CRYSTAL STRUCTURE OF PROLIDASE EAH89906 COMPLEXED WITH N- METHYLPHOSPHONATE-L-PROLINE | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, PROLIDASE, NYSGXRC, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, HYDROLASE
3n3e:A (ILE130) to (ARG163) ZEBRAFISH ALPHAA CRYSTALLIN | PROTEIN CHAPERONE, EYE LENS TRANSPARENCY, CHAPERONE
3n3e:B (ILE130) to (VAL161) ZEBRAFISH ALPHAA CRYSTALLIN | PROTEIN CHAPERONE, EYE LENS TRANSPARENCY, CHAPERONE
4bwu:A (ALA1) to (ASP37) THREE-DIMENSIONAL STRUCTURE OF THE K109A MUTANT OF PARACOCCUS PANTOTROPHUS PSEUDOAZURIN AT PH 5.5 | ELECTRON TRANSPORT
3cbm:A (LEU169) to (PHE193) SET7/9-ER-ADOMET COMPLEX | ESTROGEN RECEPTOR, PROTEIN LYSINE METHYLATION, ACTIVATOR, CHROMATIN REGULATOR, CHROMOSOMAL PROTEIN, METHYLTRANSFERASE, NUCLEUS, S-ADENOSYL-L-METHIONINE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, ALTERNATIVE SPLICING, DNA-BINDING, LIPID-BINDING, METAL-BINDING, PHOSPHOPROTEIN, POLYMORPHISM, STEROID-BINDING, ZINC, ZINC-FINGER, TRANSFERASE/TRANSFERASE RECEPTOR COMPLEX
4c0u:B (VAL13) to (GLY34) CRYO-EM RECONSTRUCTION OF ENTEROVIRUS 71 IN COMPLEX WITH A NEUTRALIZING ANTIBODY E18 | VIRUS-IMMUNE SYSTEM COMPLEX, VIRUS, PATHOGEN, EV71
4c10:B (VAL13) to (GLY34) CRYO-EM RECONSTRUCTION OF EMPTY ENTEROVIRUS 71 IN COMPLEX WITH A NEUTRALIZING ANTIBODY E19 | VIRUS-IMMUNE SYSTEM COMPLEX, VIRUS, EV71, PATHOGEN
5fky:A (PRO606) to (ASP636) STRUCTURE OF A HYDROLASE BOUND WITH AN INHIBITOR | HYDROLASE
3cfc:L (ILE2) to (LEU33) HIGH-RESOLUTION STRUCTURE OF BLUE FLUORESCENT ANTIBODY EP2-19G2 | IMMUNOGLOBULIN, BLUE-FLUORESCENT ANTIBODY, HAPTEN COMPLEX, IMMUNE SYSTEM, ELECTRON TRANSFER
3ndx:B (VAL11) to (GLU34) HIV-1 PROTEASE SAQUINAVIR:RITONAVIR 1:50 COMPLEX STRUCTURE | HIV-1 PROTEASE, HYDROLASE, AIDS, ASPARTYL PROTEASE, SAQUINAVIR, CARBAMYLATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3cgu:B (CYS359) to (PRO389) CRYSTAL STRUCTURE OF UNLIGANDED ARGOS | ARGOS, SPITZ, EGF, EGFR INHIBITOR, DEVELOPMENTAL PROTEIN, GLYCOPROTEIN, SECRETED, SENSORY TRANSDUCTION, VISION, HORMONE/SIGNALING PROTEIN COMPLEX
4rfb:C (LYS126) to (SER160) 1.93 ANGSTROM CRYSTAL STRUCTURE OF SUPERANTIGEN-LIKE PROTEIN FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH SIALYL-LEWIS X. | SIALYL-LEWIS X, SUPERANTIGEN-LIKE PROTEIN, CSGID, STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, TOXIN
4rfb:D (GLU127) to (SER160) 1.93 ANGSTROM CRYSTAL STRUCTURE OF SUPERANTIGEN-LIKE PROTEIN FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH SIALYL-LEWIS X. | SIALYL-LEWIS X, SUPERANTIGEN-LIKE PROTEIN, CSGID, STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, TOXIN
4rgh:A (LEU204) to (SER229) HUMAN DNA DAMAGE-INDUCIBLE PROTEIN: FROM PROTEIN CHEMISTRY AND 3D STRUCTURE TO DECIPHERING ITS CELLULAR ROLE | RETROVIRAL PROTEASE-LIKE DOMAIN, PUTATIVE PROTEOLYTICAL ACTIVITY, HYDROLASE
4rh6:C (ILE131) to (LEU159) 2.9 ANGSTROM CRYSTAL STRUCTURE OF PUTATIVE EXOTOXIN 3 FROM STAPHYLOCOCCUS AUREUS. | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, SUPERANTIGEN-LIKE PROTEIN, EXOTOXIN 3, TOXIN
3ckt:B (ARG8) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH A DIMETHYLALLYL DECORATED PYRROLIDINE BASED INHIBITOR (ORTHOROMBIC SPACE GROUP) | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4rh7:A (GLU4265) to (LEU4304) CRYSTAL STRUCTURE OF HUMAN CYTOPLASMIC DYNEIN 2 MOTOR DOMAIN IN COMPLEX WITH ADP.VI | AAA+ PROTEIN, MOTOR PROTEIN, DYNEIN MOTOR DOMAIN
5fpi:A (PRO286) to (LYS319) MU2 ADAPTIN SUBUNIT OF THE AP2 ADAPTOR (C-TERMINAL DOMAIN) COMPLEXED WITH INTEGRIN ALPHA4 INTERNALISATION PEPTIDE QYKSILQE | ENDOCYTOSIS, CLATHRIN ADAPTOR
3no2:A (GLN263) to (PRO291) CRYSTAL STRUCTURE OF A PROTEIN OF UNKNOWN FUNCTION (BACCAC_01654) FROM BACTEROIDES CACCAE AT 1.35 A RESOLUTION | SIX-BLADED BETA-PROPELLER, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
4cai:A (LEU947) to (ASP996) STRUCTURE OF INNER DYSF DOMAIN OF HUMAN DYSFERLIN | MEMBRANE PROTEIN, MEMBRANE REPAIR, LIMB-GIRDLE MUSCULAR DYSTROPHY, DYSF DOMAIN
3nu5:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT I50V WITH ANTIVIRAL DRUG AMPRENAVIR | ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3nu5:B (VAL111) to (GLU134) CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT I50V WITH ANTIVIRAL DRUG AMPRENAVIR | ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3nuj:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT I54V WITH ANTIVIRAL DRUG AMPRENAVIR | ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3nuk:A (GLY610) to (ASP646) THE CRYSTAL STRUCTURE OF THE W169Y MUTANT OF ALPHA-GLUCOSIDASE (FAMILY 31) FROM RUMINOCOCCUS OBEUM ATCC 29174 | STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, (BETA/ALPHA)8 BARREL, GLYCOSYLE HYDROLYSIS, HYDROLASE
3cs0:A (VAL27) to (THR102) CRYSTAL STRUCTURE OF DEGP24 | DEGP, HTRA, PROTEASE, CHAPERONE, PDZ, OUTER MEMBRANE PROTEIN, OMP, PERIPLASM, HYDROLASE
3nwq:A (VAL11) to (GLU34) X-RAY STRUCTURE OF ESTER CHEMICAL ANALOGUE [O-ILE50,O-ILE50']HIV-1 PROTEASE COMPLEXED WITH MVT-101 | BETA-BARREL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3nwx:A (VAL11) to (GLU34) X-RAY STRUCTURE OF ESTER CHEMICAL ANALOGUE [O-ILE50,O-ILE50']HIV-1 PROTEASE COMPLEXED WITH KVS-1 INHIBITOR | BETA-BARREL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5fwk:B (ASN352) to (GLU384) ATOMIC CRYOEM STRUCTURE OF HSP90-CDC37-CDK4 COMPLEX | SIGNALING PROTEIN, HSP90, CDC37, CDK4, CHAPERONE, KINASE, UNFOLDING
5fwm:B (ASN352) to (GLU384) ATOMIC CRYOEM STRUCTURE OF HSP90-CDC37-CDK4 COMPLEX | HSP90, CDC37, CDK4, CHAPERONE, KINASE, UNFOLDING
4rvx:C (THR12) to (GLU34) CRYSTAL STRUCTURE OF MULTIDRUG-RESISTANT CLINICAL ISOLATE A02 HIV-1 PROTEASE IN COMPLEX WITH NON-PEPTIDIC INHIBITOR, GRL079 | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, HIV-1 PROTEASE- INHIBITOR COMPLEX, GRL079, NON-PEPTIDIC PROTEASE INHIBITOR
4coe:B (VAL111) to (GLU134) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, ENZYME
3d1z:B (ARG8) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 MUTANT I54M AND INHIBITOR DARUNAVIR | DRUG RESISTANCE; HIV-1, FLAP MUTANT, I54M, DARUNAVIR, HYDROLASE
3d20:B (VAL111) to (GLU134) CRYSTAL STRUCTURE OF HIV-1 MUTANT I54V AND INHIBITOR DARUNAVIA | DRUG RESISTANCE; HIV-1, I54V, FLAP MUTANT, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC-FINGER
4cpr:A (VAL11) to (GLU34) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
4cpr:B (VAL111) to (GLU134) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
4cps:A (VAL11) to (GLU34) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
4cps:B (VAL111) to (GLU134) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
4cpx:A (VAL11) to (GLU34) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
4cpx:B (VAL111) to (GLU134) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
4cpt:A (VAL11) to (GLU34) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, HIV-1 PROTEASE, INHIBITOR, RATIONAL DRUG DESIGN, ENZYME
4cpt:B (VAL111) to (GLU134) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, HIV-1 PROTEASE, INHIBITOR, RATIONAL DRUG DESIGN, ENZYME
4cpu:A (VAL11) to (GLU34) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, HIV-1 PROTEASE, INHIBITOR, RATIONAL DRUG DESIGN
4cpu:B (VAL111) to (GLU134) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, HIV-1 PROTEASE, INHIBITOR, RATIONAL DRUG DESIGN
4cpw:A (VAL11) to (GLU34) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
4cpw:B (VAL111) to (GLU134) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
3o99:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD13 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3o9a:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD14 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3o9b:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD25 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3o9d:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD19 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3o9f:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD27 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3o9f:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD27 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3o9g:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF53 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3d7f:A (TYR127) to (GLY172) A HIGH RESOLUTION CRYSTAL STRUCTURE OF HUMAN GLUTAMATE CARBOXYPEPTIDASE II (GCPII) IN A COMPLEX WITH DCIT, A UREA-BASED INHIBITOR | PROSTATE SPECIFIC MEMBRANE ANTIGEN; METALLOPEPTIDASE; FOLATE HYDROLASE; GLUTAMATE CARBOXYPEPTIDASE II; NAALADASE, DCIT, UREA- BASED INHIBITOR, CARBOXYPEPTIDASE, DIPEPTIDASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, METAL-BINDING, METALLOPROTEASE, MULTIFUNCTIONAL ENZYME, PROTEASE, SIGNAL-ANCHOR, TRANSMEMBRANE
3obj:A (THR7) to (GLY31) CONFORMATIONAL PLASTICITY OF P38 MAP KINASE DFG MUTANTS IN RESPONSE TO INHIBITOR BINDING | TRANSFERASE
4cvb:A (ARG310) to (VAL343) CRYSTAL STRUCTURE OF QUINONE-DEPENDENT ALCOHOL DEHYDROGENASE FROM PSEUDOGLUCONOBACTER SACCHAROKETOGENENES | OXIDOREDUCTASE, CARBOHYDRATE OXIDATION, QUINOPROTEIN
4cvc:A (ARG310) to (VAL343) CRYSTAL STRUCTURE OF QUINONE-DEPENDENT ALCOHOL DEHYDROGENASE FROM PSEUDOGLUCONOBACTER SACCHAROKETOGENENES WITH ZINC IN THE ACTIVE SITE | OXIDOREDUCTASE, CARBOHYDRATE OXIDATION, QUINOPROTEIN
3djk:B (VAL111) to (GLU134) WILD TYPE HIV-1 PROTEASE WITH POTENT ANTIVIRAL INHIBITOR GRL-0255A | HIV-1, WILD TYPE PROTEASE, PROTEASE INHIBITOR, HYDROLASE, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, LIPOPROTEIN, MAGNESIUM, METAL- BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER
3dk1:B (VAL111) to (GLU134) WILD TYPE HIV-1 PROTEASE WITH POTENT ANTIVIRAL INHIBITOR GRL-0105A | HIV-1, WILD TYPE PROTEASE, PROTEASE INHIBITOR, HYDROLASE, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, LIPOPROTEIN, MAGNESIUM, METAL- BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER
5gmg:B (ALA238) to (PRO282) CRYSTAL STRUCTURE OF MONKEY TLR7 IN COMPLEX WITH LOXORIBINE AND POLYU | IMMUNE SYSTEM, TLR7, INNATE IMMUNITY, SSRNA RECOGNITON, IMMUNE SYSTEM-RNA COMPLEX
4tvg:B (ARG8) to (GLU34) HIV PROTEASE (PR) DIMER IN CLOSED FORM WITH PEPSTATIN IN ACTIVE SITE AND FRAGMENT AK-2097 IN THE OUTSIDE/TOP OF FLAP | APO PROTEASE, ALLOSTERY, FRAGMENT BINDING
4tvh:A (ARG8) to (GLU34) HIV PROTEASE (PR) DIMER IN CLOSED FORM WITH TL-3 IN ACTIVE SITE AND FRAGMENT AK-2097 IN THE OUTSIDE/TOP OF FLAP | HIV PROTEASE, ALLOSTERY, FRAGMENT BINDING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4twe:B (PRO114) to (GLY161) STRUCTURE OF LIGAND-FREE N-ACETYLATED-ALPHA-LINKED-ACIDIC-DIPEPTIDASE LIKE PROTEIN (NAALADASEL) | METALLOPROTEIN, GLYCOPROTEIN, HYDROLASE
3opm:C (ASN263) to (THR307) CRYSTAL STRUCTURE OF HUMAN DPP4 BOUND TO TAK-294 | PROTEASE AND 8-BLADED BETA-PROPELLER DOMAIN, AMINOPEPTIDASE, CELL MEMBRANE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, SERINE PROTEASE, SIGNAL-ANCHOR, TRANSMEMBRANE, SIGNALING PROTEIN, HYDROLASE-HYDROLASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4d94:A (GLN798) to (PRO839) CRYSTAL STRUCTURE OF TEP1R | PLASMODIUM REFRACTORY ALLELE, IMMUNE SYSTEM, FULL-LENGTH PROTEIN, THIOESTER, MACROGLOBULIN DOMAINS, COMPONENT OF INNATE IMMUNE RESPONSE BY THE OPSINIZATION AND MELANIZATION OF PATHOGENS
3oqg:A (GLU36) to (ILE67) RESTRICTION ENDONUCLEASE HPY188I IN COMPLEX WITH SUBSTRATE DNA | ENDONUCLEASE-DNA COMPLEX, RESTRICTION ENZYME, HPY188I, INTERCALATION, GIY-YIG NUCLEASE, CATALYTIC MECHANISM, PSEUDOPALINDROME, HYDROLASE- DNA COMPLEX
3oqg:B (GLU36) to (ILE67) RESTRICTION ENDONUCLEASE HPY188I IN COMPLEX WITH SUBSTRATE DNA | ENDONUCLEASE-DNA COMPLEX, RESTRICTION ENZYME, HPY188I, INTERCALATION, GIY-YIG NUCLEASE, CATALYTIC MECHANISM, PSEUDOPALINDROME, HYDROLASE- DNA COMPLEX
3or3:A (GLU36) to (ILE67) RESTRICTION ENDONUCLEASE HPY188I IN COMPLEX WITH PRODUCT DNA | ENDONUCLEASE-DNA COMPLEX, RESTRICTION ENZYME, HPY188I, INTERCALATION, GIY-YIG NUCLEASE, CATALYTIC MECHANISM, PSEUDOPALINDROME, HYDROLASE- DNA COMPLEX, RESTRICTION ENDONUCLEASE, DNA
4u2z:A (TRP75) to (GLY108) X-RAY CRYSTAL STRUCTURE OF AN SCO GLGEI-V279S/1,2,2-TRIFLUROMALTOSE COMPLEX | INHIBITOR COMPLEX FLUOROSUGAR MALTOSYL TRANSFERASE, TRANSFERASE
3oxw:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 I50V, A71V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR DARUNAVIR | HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, DRUG RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3oxw:C (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 I50V, A71V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR DARUNAVIR | HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, DRUG RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3oxx:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 I50V, A71V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR ATAZANAVIR | HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3oxx:C (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 I50V, A71V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR ATAZANAVIR | HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3oy4:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 L76V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR DARUNAVIR. | HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3oy4:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 L76V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR DARUNAVIR. | HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4dfg:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE WITH CYCLOPENTYLTETRAHYDRO- FURANYL URETHANES AS P2-LIGAND, GRL-0249A | ASPARTIC ACID PROTEASE, HIV-1 PROTEASE INHIBITOR GRL-0249A, CYCLOPENTYLTETRAHYDRO- FURANYL URETHANES P2-LIGANDS, WILD-TYPE HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ozk:A (PHE44) to (ILE73) CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN VARIANT A25T IN COMPLEX WITH THYROXINE (T4) | T4 TRANSPORT, RETINOL BINDING PROTEIN, HORMONE
3ozv:B (THR191) to (GLY227) THE CRYSTAL STRUCTURE OF FLAVOHEMOGLOBIN FROM R. EUTROPHUS IN COMPLEX WITH ECONAZOLE | GLOBIN FOLD, ANTIPARALLEL BETA-BARREL, ALPHA/BETA FOLD, HEM-, FAD-, NAD- BINDING DOMAINS, LIPID BINDING PROTEIN
4dhj:A (GLY226) to (PRO265) THE STRUCTURE OF A CEOTUB1 UBIQUITIN ALDEHYDE UBC13~UB COMPLEX | UBIQUITINATION, HYDROLASE-SIGNALING PROTEIN-LIGASE COMPLEX
5hj3:C (GLU106) to (GLY143) CRYSTAL STRUCTURE OF HOST-PRIMED EBOLA VIRUS GP, GPCL. | EBOLA VIRUS, EOV, EBOLAVIRUS, GP, GLYCOPROTEIN, GPCL, CLEAVED, PRIMED, PROTEOLYTICALLY, RECEPTOR BINDING POCKET, CREST, TROUGH, MR72, KZ52, BROADLY NEUTRALIZING, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
5hj3:O (GLU106) to (GLY143) CRYSTAL STRUCTURE OF HOST-PRIMED EBOLA VIRUS GP, GPCL. | EBOLA VIRUS, EOV, EBOLAVIRUS, GP, GLYCOPROTEIN, GPCL, CLEAVED, PRIMED, PROTEOLYTICALLY, RECEPTOR BINDING POCKET, CREST, TROUGH, MR72, KZ52, BROADLY NEUTRALIZING, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
4u60:E (SER44) to (TRP113) TRICHODYSPLASIA SPINULOSA-ASSOCIATED POLYOMAVIRUS (TSPYV) VP1 IN COMPLEX WITH GM1 OLIGOSACCHARIDE | VIRAL COAT PROTEIN, JELLY-ROLL FOLD, CARBOHYDRATE BINDING, VIRAL PROTEIN
4djm:H (LYS162) to (VAL189) CRYSTAL STRUCTURE OF THE E. COLI CHAPERONE DRAB | DRAB, CHAPERONE, PILI
4djq:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH MKP86 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4djr:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH MKP97 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4u67:1 (LYS11) to (LYS39) CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT (50S) OF DEINOCOCCUS RADIODURANS CONTAINING A THREE RESIDUE INSERTION IN L22 | RIBOSOME, ANTIBIOTICS, RESISTANCE, ERYTHROMYCIN
5hly:A (THR120) to (LYS163) STRUCTURE OF PRO-ACTIVIN A PRECURSOR AT 2.3 A RESOLUTION | GROWTH FACTOR, PRECURSOR, SIGNALLING, SIGNALING PROTEIN
3p7c:A (THR7) to (GLY31) P38 INHIBITOR-BOUND | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3e1x:B (GLY197) to (LEU230) THE CRYSTAL STRUCTURE OF APO PROSTASIN AT 1.7 ANGSTROMS RESOLUTION | PROSTASIN, ENAC, HCAP-1, CHANNEL ACTIVATING PROTEASE, CELL MEMBRANE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, PROTEASE, SECRETED, SERINE PROTEASE, TRANSMEMBRANE, ZYMOGEN
5hp5:A (VAL7) to (ASP28) SRTUCTURE OF HUMAN PEPTIDYLARGININE DEIMINASE TYPE I (PAD1) | PEPTIDYLARGININE DEIMINASE, PAD1, ISOZYME, MONOMER, HYDROLASE
5hp5:B (ARG5) to (ASP28) SRTUCTURE OF HUMAN PEPTIDYLARGININE DEIMINASE TYPE I (PAD1) | PEPTIDYLARGININE DEIMINASE, PAD1, ISOZYME, MONOMER, HYDROLASE
5hvp:B (PRO209) to (GLU234) CRYSTALLOGRAPHIC ANALYSIS OF A COMPLEX BETWEEN HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE AND ACETYL-PEPSTATIN AT 2.0-ANGSTROMS RESOLUTION | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3pha:C (GLY610) to (ASP646) THE CRYSTAL STRUCTURE OF THE W169Y MUTANT OF ALPHA-GLUCOSIDASE (GH31 FAMILY) FROM RUMINOCOCCUS OBEUM ATCC 29174 IN COMPLEX WITH ACARBOSE | STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, STRUCTURALCOMPLEX, MCSG, MIDWEST CENTER FOR STRUCTURAL GENOMICS, HYDROLASE, (BETA/ALPHA)8-BARREL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4dxf:A (LYS99) to (SER133) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN 4 | OLIGONUCLEOTIDE/OLIGOSACCHARIDE BINDING FOLD, BETA GRASP FOLD, SUPERANTIGEN FOLD, CARBOHYDRATE BINDING, SUGAR BINDING PROTEIN
4dxg:A (LYS99) to (SER133) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN 4 COMPLEXED WITH SIALYL LEWIS X | OLIGONUCLEOTIDE/OLIGOSACCHARIDE BINDING FOLD, BETA GRASP FOLD, SUPERANTIGEN FOLD, CARBOHYDRATE BINDING, SUGAR BINDING PROTEIN
4uoj:A (LYS863) to (TYR886) STRUCTURE OF FUNGAL BETA-MANNOSIDASE (GH2) FROM TRICHODERMA HARZIANUM | HYDROLASE
4uoj:B (LYS863) to (TYR886) STRUCTURE OF FUNGAL BETA-MANNOSIDASE (GH2) FROM TRICHODERMA HARZIANUM | HYDROLASE
4upj:B (VAL11) to (GLY35) HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 PROTEASE MUTANT WITH LYS 57 REPLACED BY LEU (K57L) COMPLEX WITH U097410 [4-HYDROXY-3-[1-[3- [[[[(TERT-BUTYLOXYCARBONYL) AMINOMETHYL]CARBONYL]AMINO]PHENYL]PROPYL]COUMARIN | HYDROLASE (ACID PROTEASE)
4uqi:M (ASN171) to (ASN217) AP2 CONTROLS CLATHRIN POLYMERIZATION WITH A MEMBRANE- ACTIVATED SWITCH | ENDOCYTOSIS, PROTEIN TRANSPORT, LIPID BINDING
4uqi:M (PRO286) to (GLN318) AP2 CONTROLS CLATHRIN POLYMERIZATION WITH A MEMBRANE- ACTIVATED SWITCH | ENDOCYTOSIS, PROTEIN TRANSPORT, LIPID BINDING
4e47:B (LEU169) to (PHE193) SET7/9 IN COMPLEX WITH INHIBITOR (R)-(3-(3-CYANOPHENYL)-1-OXO-1- (PYRROLIDIN-1-YL)PROPAN-2-YL)-1,2,3,4-TETRAHYDROISOQUINOLINE-6- SULFONAMIDE AND S-ADENOSYLMETHIONINE | TERNARY COMPLEX, SET DOMAIN, METHYLTRANSFERASE, INHIBITOR, S- ADENOSYLMETHIONINE, CHROMATIN REGULATOR, CHROMOSOMAL PROTEIN, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4uti:A (GLU6) to (TYR27) XENA - OXIDIZED - Y183F VARIANT IN COMPLEX WITH COUMARIN | OXIDOREDUCTASE
4uth:A (GLU6) to (TYR27) XENA - OXIDIZED - Y183F VARIANT | OXIDOREDUCTASE
4utj:A (GLU6) to (TYR27) XENA - OXIDIZED - Y183F VARIANT IN COMPLEX WITH 8-HYDROXYCOUMARIN | OXIDOREDUCTASE
4utm:A (GLU6) to (TYR27) XENA - REDUCED - Y183F VARIANT IN COMPLEX WITH 8-HYDROXYCOUMARIN | OXIDOREDUCTASE
3psu:A (ARG8) to (GLU34) HIV-1 PROTEASE IN COMPLEX WITH AN ISOBUTYL DECORATED OLIGOAMINE (SYMMETRIC BINDING MODE) | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3pty:A (GLY913) to (GLN950) CRYSTAL STRUCTURE OF THE C-TERMINAL EXTRACELLULAR DOMAIN OF MYCOBACTERIUM TUBERCULOSIS EMBC | BETA-SANDWICH, CARBOHYDRATE BINDING, CARBOHYDRATE, TRANSFERASE
4ecp:A (TYR42) to (GLU73) X-RAY CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATE PPA FROM MYCOBACTERIUM LEPRAE | STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, HYDROLASE
4ecp:B (TYR42) to (GLU73) X-RAY CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATE PPA FROM MYCOBACTERIUM LEPRAE | STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, HYDROLASE
3pvn:E (GLY72) to (GLU101) TRICLINIC FORM OF HUMAN C-REACTIVE PROTEIN IN COMPLEX WITH ZINC | PENTRAXIN FAMILY, IMMUNE SYSTEM
4ejd:B (VAL11) to (GLU34) HIV PROTEASE (PR) DIMER IN CLOSED FORM WITH PEPSTATIN IN ACTIVE SITE AND FRAGMENT 1F1 IN THE OUTSIDE/TOP OF FLAP | APO PROTEASE, ALLOSTERY, FRAGMENT BINDING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3q0t:B (ALA261) to (THR307) CRYSTAL STRUCTURE OF HUMAN DPP-IV IN COMPLEX WITHSA-(+)- METHYL2-(3- (AMINOMETHYL)-4-(2,4-DICHLOROPHENYL)-2-METHYL- 7-OXO-5H-PYRROLO[3,4- B]PYRIDIN-6(7H)-YL)ACETATE | EXOPEPTIDASE, ALPHA/BETA HYDROLASE FOLD, BETA BARREL, BETA PROPELLER, AMINOPEPTIDASE, GLYCOPROTEIN, MEMBRANE, SERINE PROTEASE, SIGNAL- ANCHOR, TRANSMEMBRANE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4epj:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE SINGLE CHAIN WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH THE SUBSTRATE P2-NC | HIV-1 PROTEASE, SPECIFICITY DESIGN, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE SUBSTRATE COMPLEX
4eq0:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE SINGLE CHAIN VARIANT OF HIV-1 PROTEASE IN COMPLEX WITH THE SUBSTRATE P2-NC | HIV-1 PROTEASE, SPECIFICITY DESIGN, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE SUBSTRATE COMPLEX
3q6m:B (ASN360) to (GLU392) CRYSTAL STRUCTURE OF HUMAN MC-HSP90 IN C2221 SPACE GROUP | THREE DOMAINS, TRIMER OF DIMER, HEXAMER, CHAPERONE
3q6m:C (ASN360) to (GLU392) CRYSTAL STRUCTURE OF HUMAN MC-HSP90 IN C2221 SPACE GROUP | THREE DOMAINS, TRIMER OF DIMER, HEXAMER, CHAPERONE
3q6n:D (ASN360) to (GLU392) CRYSTAL STRUCTURE OF HUMAN MC-HSP90 IN P21 SPACE GROUP | THREE DOMAINS, TRIMER OF DIMER, HEXAMER, CHAPERONE
4es8:B (GLY78) to (HIS107) CRYSTAL STRUCTURE OF THE ADHESIN DOMAIN OF EPF FROM STREPTOCOCCUS PYOGENES IN P212121 | CARBOHYDRATE-BINDING MODULE, FIBRONECTIN-LIKE DOMAIN, ADHESIN, EXTRACELLULAR, CELL ADHESION
5ivr:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH METHYL N-[(1S)-1-[[2- [(3S)-3-[(4-AMINOPHENYL)METHYLAMINO]-4-HYDROXY- BUTYL]PHENYL]CARBAMOYL]-2,2-DIPHENYL-ETHYL]CARBAMATE | HIV, PROTEASE, HYDROLASE-INHIBITOR COMPLEX
5ivr:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH METHYL N-[(1S)-1-[[2- [(3S)-3-[(4-AMINOPHENYL)METHYLAMINO]-4-HYDROXY- BUTYL]PHENYL]CARBAMOYL]-2,2-DIPHENYL-ETHYL]CARBAMATE | HIV, PROTEASE, HYDROLASE-INHIBITOR COMPLEX
5ivs:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH METHYL N-[(1S)-1- BENZHYDRYL-2-[2-[2-[(2R,5S)-5-(BENZYLCARBAMOYLOXYMETHYL)MORPHOLIN-2- YL]ETHYL]ANILINO]-2-OXO-ETHYL]CARBAMATE | HIV, PROTEASE, HYDROLASE-INHIBITOR COMPLEX
3qbf:B (ARG8) to (GLU34) HIV-1 PROTEASE (MUTANT Q7K L33I L63I) IN COMPLEX WITH A THREE-ARMED PYRROLIDINE-BASED INHIBITOR | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5j09:J (ARG160) to (GLN239) CRYSTAL STRUCTURE OF DECAMERIC BFDV CAPSID PROTEIN | BFDV VIRUS CAPSID JELLY ROLL, VIRUS
4f74:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF ACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE N TERMINAL PRODUCT OF THE SUBSTRATE MA-CA. | HIV-1 PROTEASE, SUBSTRATE COMPLEX, AIDS, PRODUCT COMPLEX, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE PRODUCT COMPLEX
4f74:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF ACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE N TERMINAL PRODUCT OF THE SUBSTRATE MA-CA. | HIV-1 PROTEASE, SUBSTRATE COMPLEX, AIDS, PRODUCT COMPLEX, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE PRODUCT COMPLEX
4f75:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF ACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE N TERMINAL PRODUCT OF THE SUBSTRATE RH-IN | HIV-1 PROTEASE, SUBSTRATE COMPLEX, AIDS, PRODUCT COMPLEX, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE PRODUCT COMPLEX
4f76:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF THE ACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE PRODUCTS OF P1-P6 SUBSTRATE | HIV-1 PROTEASE, SUBSTRATE COMPLEX, AIDS, PRODUCT COMPLEX, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE PRODUCT COMPLEX
5j7o:E (ALA67) to (ALA109) FAUSTOVIRUS MAJOR CAPSID PROTEIN | VIRUS, CAPSID, DOUBLE JELLY-ROLL, VIRAL PROTEIN
5j7u:A (ALA66) to (ALA113) FAUSTOVIRUS MAJOR CAPSID PROTEIN | VIRUS, CAPSID, DOUBLE JELLY-ROLL, VIRAL PROTEIN
5j7u:D (ALA66) to (ALA109) FAUSTOVIRUS MAJOR CAPSID PROTEIN | VIRUS, CAPSID, DOUBLE JELLY-ROLL, VIRAL PROTEIN
5j7u:D (ARG421) to (ALA453) FAUSTOVIRUS MAJOR CAPSID PROTEIN | VIRUS, CAPSID, DOUBLE JELLY-ROLL, VIRAL PROTEIN
5j7u:G (ALA66) to (ALA109) FAUSTOVIRUS MAJOR CAPSID PROTEIN | VIRUS, CAPSID, DOUBLE JELLY-ROLL, VIRAL PROTEIN
5j7u:J (ARG421) to (ALA453) FAUSTOVIRUS MAJOR CAPSID PROTEIN | VIRUS, CAPSID, DOUBLE JELLY-ROLL, VIRAL PROTEIN
5j7u:L (ALA66) to (ALA113) FAUSTOVIRUS MAJOR CAPSID PROTEIN | VIRUS, CAPSID, DOUBLE JELLY-ROLL, VIRAL PROTEIN
4v15:B (GLY313) to (VAL344) CRYSTAL STRUCTURE OF D-THREONINE ALDOLASE FROM ALCALIGENES XYLOSOXIDANS | LYASE, DEGRADATION, VITAMIN B6- ENZYME FOLD-TYPE III, ALANINE RACEMASE- LIKE DOMAIN
4v17:A (LEU447) to (ALA475) STRUCTURE OF A NOVEL CARBOHYDRATE BINDING MODULE FROM GLYCOSIDE HYDROLASE FAMILY 5 GLUCANASE FROM RUMINOCOCCUS FLAVEFACIENS FD-1 | SUGAR BINDING PROTEIN
4v17:B (LEU447) to (ALA475) STRUCTURE OF A NOVEL CARBOHYDRATE BINDING MODULE FROM GLYCOSIDE HYDROLASE FAMILY 5 GLUCANASE FROM RUMINOCOCCUS FLAVEFACIENS FD-1 | SUGAR BINDING PROTEIN
3qpj:B (VAL11) to (GLU34) HIV-1 PROTEASE (MUTANT Q7K L33I L63I) IN COMPLEX WITH A THREE-ARMED PYRROLIDINE-BASED INHIBITOR | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3qrm:B (ARG8) to (GLU34) HIV-1 PROTEASE (MUTANT Q7K L33I L63I) IN COMPLEX WITH A THREE-ARMED PYRROLIDINE-BASED INHIBITOR | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4fe6:A (PRO9) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH AN ENAMINO- OXINDOLE INHIBITOR | HYDROLASE-INHIBITOR COMPLEX
4v26:A (GLN333) to (PRO364) VER-246608, A NOVEL PAN-ISOFORM ATP COMPETITIVE INHIBITOR OF PYRUVATE DEHYDROGENASE KINASE, DISRUPTS WARBURG METABOLISM AND INDUCES CONTEXT-DEPENDENT CYTOSTASIS IN CANCER CELLS | TRANSFERASE, GLYCOLYSIS, WARBURG METABOLISM, NOV3R
3r4r:A (ALA221) to (TYR254) CRYSTAL STRUCTURE OF A FIMBRIAL ASSEMBLY PROTEIN (BDI_3522) FROM PARABACTEROIDES DISTASONIS ATCC 8503 AT 2.38 A RESOLUTION | TRANSTHYRETIN-LIKE (ALSO KNOWN AS PREALBUMIN-LIKE), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, CELL ADHESION
4fl8:B (VAL11) to (GLU34) HIV-1 PROTEASE COMPLEXED WITH GEM-DIOL-AMINE TETRAHEDRAL INTERMEDIATE | HYDROLASE, CATALYTIC MECHANISM, DRUG RESISTANCE, ASPARTIC PROTEASE
5jg1:B (VAL11) to (GLU34) HIV-1 WILD TYPE PROTEASE WITH GRL-031-14A (A ADAMANTANE P1-LIGAND WITH TETRAHYDROPYRANO-TETRAHYDROFURAN IN P2 AND ISOBUTYLAMINE IN P1') | ADAMANTANE, HIV-1 PROTEASE INHIBITOR GRL-031-14A, DARUNAVIR, MULTIDRUG-RESISTANT, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5ji7:A (TYR177) to (ALA204) THE CRYSTAL STRUCTURE OF IUS-SPRY DOMAIN FROM RANBPM/9 | BETA SANDWICH, RAN-BINDING PROTEIN
5jpm:C (GLU1463) to (ALA1496) STRUCTURE OF THE COMPLEX OF HUMAN COMPLEMENT C4 WITH MASP-2 REBUILT USING IMDFF | COMPLEMENT, IMMUNE SYSTEM, BLOOD
5jpm:E (ALA938) to (ALA982) STRUCTURE OF THE COMPLEX OF HUMAN COMPLEMENT C4 WITH MASP-2 REBUILT USING IMDFF | COMPLEMENT, IMMUNE SYSTEM, BLOOD
5jpn:C (GLU1463) to (ALA1496) STRUCTURE OF HUMAN COMPLEMENT C4 REBUILT USING IMDFF | COMPLEMENT, IMMUNE SYSTEM, BLOOD
4fxg:B (MET1220) to (SER1251) COMPLEMENT C4 IN COMPLEX WITH MASP-2 | IMMUNE SYSTEM, COMPLEMENT, PROTEOLYTIC CASCADE
4fxg:C (GLU1463) to (ALA1496) COMPLEMENT C4 IN COMPLEX WITH MASP-2 | IMMUNE SYSTEM, COMPLEMENT, PROTEOLYTIC CASCADE
4fxg:E (ALA1221) to (SER1251) COMPLEMENT C4 IN COMPLEX WITH MASP-2 | IMMUNE SYSTEM, COMPLEMENT, PROTEOLYTIC CASCADE
4fxg:F (GLU1463) to (ALA1496) COMPLEMENT C4 IN COMPLEX WITH MASP-2 | IMMUNE SYSTEM, COMPLEMENT, PROTEOLYTIC CASCADE
4fxk:C (GLU1463) to (ALA1496) HUMAN COMPLEMENT C4 | IMMUNE SYSTEM, COMPLEMENT, PROTEOLYTIC CASCADE
5jtw:E (ALA938) to (ASP984) CRYSTAL STRUCTURE OF COMPLEMENT C4B RE-REFINED USING IMDFF | INNATE IMMUNE SYSTEM, COMPLEMENT, ACTIVE FORM, IMMUNE SYSTEM
4g8a:A (PHE533) to (LYS561) CRYSTAL STRUCTURE OF HUMAN TLR4 POLYMORPHIC VARIANT D299G AND T399I IN COMPLEX WITH MD-2 AND LPS | LEUCINE RICH REPEAT MD-2 RELATED LIPID RECOGNITION, RECEPTOR, INNATE IMMUNITY, LIPID BINDING, GLYCOSYLATION, IMMUNE SYSTEM
4gbv:A (CYS92) to (PHE117) CRYSTAL STRUCTURE OF AMP COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6- BISPHOSPHATASE MUTANT A54L WITH 1,2-ETHANEDIOL AS CRYO-PROTECTANT | ALLOSTERIC ENZYMES, FBPASE, AMP, 1,2-ETHANEDIOL, HYDROLASE
5kde:A (TYR42) to (ALA73) INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH INHIBITOR 1 AND INORGANIC PYROPHOSPHATE | HYDROLASE, PYROPHOSPHATASE, DRUG TARGET, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5kdf:A (TYR42) to (ALA73) INORGANIC PYROPHOSPHATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH INHIBITOR 6 AND INORGANIC PYROPHOSPHATE | HYDROLASE, PYROPHOSPHATASE, DRUG TARGET, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4gh4:B (LEU14) to (GLY35) CRYSTAL STRUCTURE OF FOOT AND MOUTH DISEASE VIRUS A22 SEROTYPE | ICOSAHEDRAL VIRUS, CAPSIDS, PICORNAVIRUS, APTHOVIRUS, VIRUS
5lgv:A (TRP75) to (GLY108) GLGE ISOFORM 1 FROM STREPTOMYCES COELICOLOR E423A MUTANT SOAKED IN MALTOOCTAOSE | HYDROLASE, ALPHA-GLUCAN BIOSYNTHESIS, GLYCOSIDE HYDROLASE FAMILY 13_3, TRANSFERASE
5lgw:A (TRP75) to (GLY108) GLGE ISOFORM 1 FROM STREPTOMYCES COELICOLOR D394A MUTANT CO- CRYSTALLISED WITH MALTODEXTRIN | HYDROLASE, ALPHA-GLUCAN BIOSYNTHESIS, GLYCOSIDE HYDROLASE FAMILY 13_3, TRANSFERASE
5lgw:B (TRP75) to (GLY108) GLGE ISOFORM 1 FROM STREPTOMYCES COELICOLOR D394A MUTANT CO- CRYSTALLISED WITH MALTODEXTRIN | HYDROLASE, ALPHA-GLUCAN BIOSYNTHESIS, GLYCOSIDE HYDROLASE FAMILY 13_3, TRANSFERASE
7hvp:A (VAL11) to (GLU34) X-RAY CRYSTALLOGRAPHIC STRUCTURE OF A COMPLEX BETWEEN A SYNTHETIC PROTEASE OF HUMAN IMMUNODEFICIENCY VIRUS 1 AND A SUBSTRATE-BASED HYDROXYETHYLAMINE INHIBITOR | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
7upj:A (ARG8) to (GLU34) HIV-1 PROTEASE/U101935 COMPLEX | HYDROLASE, ACID PROTEASE, ASPARTYL PROTEASE
9hvp:A (ARG8) to (GLU34) DESIGN, ACTIVITY AND 2.8 ANGSTROMS CRYSTAL STRUCTURE OF A C2 SYMMETRIC INHIBITOR COMPLEXED TO HIV-1 PROTEASE | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2olu:A (ASP71) to (ASN98) STRUCTURAL INSIGHT INTO THE TRANSGLYCOSYLATION STEP OF BACTERIAL CELL WALL BIOSYNTHESIS : APOENZYME | TRANSPEPTIDASE FOLD GLYCOSYLTRANSFERASE FAMILY 51, LYSOZYME FOLD, TRANSFERASE
3el4:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INHIBITOR SAQUINAVIR (SQV) COMPLEXED WITH THE MULTIDRUG HIV-1 PROTEASE VARIANT L63P/V82T/I84V | PROTEASE INHIBITOR, DRUG RESISTANCE, HIV PROTEASE, ENTROPY-ENTHALPY COMPENSATION, AIDS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASE
1nv4:A (CYS1092) to (PHE1117) FRUCTOSE-1,6-BISPHOSPHATASE COMPLEX WITH MAGNESIUM, FRUCTOSE-6- PHOSPHATE, PHOSPHATE, EDTA AND THALLIUM (1 MM) | BISPHOSPHATASE, ALLOSTERIC ENZYMES, GLUCONEOGENESIS, HYDROLASE
2p3a:A (PRO9) to (GLU34) CRYSTAL STRUCTURE OF THE MULTI-DRUG RESISTANT MUTANT SUBTYPE B HIV PROTEASE COMPLEXED WITH TL-3 INHIBITOR | MULTI-DRUG RESISTANT MUTANT SUBTYPE B HIV PROTEASE, TL-3 INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2p3a:B (PRO9) to (GLU34) CRYSTAL STRUCTURE OF THE MULTI-DRUG RESISTANT MUTANT SUBTYPE B HIV PROTEASE COMPLEXED WITH TL-3 INHIBITOR | MULTI-DRUG RESISTANT MUTANT SUBTYPE B HIV PROTEASE, TL-3 INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1bsn:A (SER65) to (GLY86) SOLUTION STRUCTURE OF THE EPSILON SUBUNIT OF THE F1- ATPSYNTHASE FROM ESCHERICHIA COLI AND ORIENTATION OF THE SUBUNIT RELATIVE TO THE BETA SUBUNITS OF THE COMPLEX | ATPSYNTHASE, F1-ATPASE, EPSILON SUBUNIT, NMR SPECTROSCOPY, HYDROLASE
1bwa:A (PRO9) to (GLU34) HIV-1 PROTEASE (V82F/I84V) DOUBLE MUTANT COMPLEXED WITH XV638 OF DUPONT PHARMACEUTICALS | HIV-1 PROTEASE, HYDROLASE
3sa9:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF68 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3sa9:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF68 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4xam:D (VAL1466) to (ALA1496) COMPLEMENT COMPONENT C4B | COMPLEMENT COMPONENT C4, ALPHA-2-MACROGLOBULIN FAMILY, IMMUNE SYSTEM
4xam:F (VAL1466) to (ALA1496) COMPLEMENT COMPONENT C4B | COMPLEMENT COMPONENT C4, ALPHA-2-MACROGLOBULIN FAMILY, IMMUNE SYSTEM
1c70:A (ARG8) to (GLU34) ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP. | HYDROLASE
4xjj:A (THR97) to (SER127) EXTRACELLULAR DOMAIN OF TYPE II TRANSFORMING GROWTH FACTOR BETA RECEPTOR IN COMPLEX WITH 2-(2-HYDROXYETHYL)NDSB-201 | TYPE II TRANSFORMING GROWTH FACTOR BETA RECEPTOR, NDSB-201, TRANSFORMING GROWTH FACTOR BETA, KINASE, EXTRACELLULAR DOMAIN
3fsv:A (ILE81) to (CYS112) PSEUDOMONAS AERUGINOSA AZURIN WITH MUTATED METAL-BINDING LOOP SEQUENCE (CAAAHAAAM) | CUPREDOXIN FOLD, METAL-BINDING, PROTEIN-PROTEIN INTERACTION, METAL BINDING PROTEIN
3sr7:B (LEU42) to (ALA59) CRYSTAL STRUCTURE OF S. MUTANS ISOPENTENYL PYROPHOSPHATE ISOMERASE | ISOPENTENYL PYROPHOSPHATE ISOMERASE, TIM-BARREL, ISOMERASE
3st5:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE WITH C3-SUBSTITUTED HEXAHYDROCYCLOPENTAFURANYL URETHANE AS P2-LIGAND, GRL-0489A | ASPARTIC ACID PROTEASE, HIV-1 PROTEASE INHIBITOR GRL-0489A, C3- SUBSTITUTED HEXAHYDROCYCLOPENTAFURANYL URETHANE AS P2-LIGANDS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2cen:B (VAL111) to (GLU134) P1' EXTENDED HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMICKING SCAFFOLD | HIV-1, PROTEASE, INHIBITOR, ASPARTYL PROTEASE, HYDROLASE
1dmp:A (PRO9) to (GLU34) STRUCTURE OF HIV-1 PROTEASE COMPLEX | AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ACID PROTEASE, RNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, ASPARTYL PROTEINASE
1dmp:B (PRO9) to (GLU34) STRUCTURE OF HIV-1 PROTEASE COMPLEX | AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ACID PROTEASE, RNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, ASPARTYL PROTEINASE
3ggx:C (VAL11) to (GLU34) HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS | HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE
3ggx:F (VAL11) to (GLU34) HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS | HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE
2r7f:A (ALA419) to (GLN443) CRYSTAL STRUCTURE OF RIBONUCLEASE II FAMILY PROTEIN FROM DEINOCOCCUS RADIODURANS, HEXAGONAL CRYSTAL FORM. NORTHEAST STRUCTURAL GENOMICS TARGET DRR63 | RIBONUCLEASE II FAMILY PROTEIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, HYDROLASE
1ebz:B (VAL111) to (GLU134) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA388 | DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
4jec:B (VAL111) to (GLU134) JOINT NEUTRON AND X-RAY STRUCTURE OF PER-DEUTERATED HIV-1 PROTEASE IN COMPLEX WITH CLINICAL INHIBITOR AMPRENAVIR | PROTEASE, HYDROLYSIS, POLYPEPTIDES, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1qbs:B (PRO9) to (GLU34) HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY | HYDROLASE (ACID PROTEINASE), ASPARTYL PROTEASE
3tta:A (GLY86) to (SER116) CRYSTAL STRUCTURE OF M-PMV DUTPASE RELAXED END-PRODUCT (DUMP) COMPLEX | JELLY ROLL, HYDROLASE
4jna:A (CYS282) to (GLY310) CRYSTAL STRUCTURE OF THE DEPH COMPLEX WITH DIMETHYL-FK228 | DISULFIDE BOND FORMATION, FK228, DEPSIPEPTIDE, FAD-DEPENDENT OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jna:B (CYS282) to (GLY310) CRYSTAL STRUCTURE OF THE DEPH COMPLEX WITH DIMETHYL-FK228 | DISULFIDE BOND FORMATION, FK228, DEPSIPEPTIDE, FAD-DEPENDENT OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
1f1g:B (GLY240) to (ILE274) CRYSTAL STRUCTURE OF YEAST CUZNSOD EXPOSED TO NITRIC OXIDE | NITRIC OXIDE, CUZNSOD, OXIDOREDUCTASE
2uxs:A (TYR49) to (ALA80) 2.7A CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE (RV3628) FROM MYCOBACTERIUM TUBERCULOSIS AT PH 7.5 | PPASE, RV3628, HYDROLASE, MAGNESIUM, METAL-BINDING, INORGANIC PYROPHOSPHATASE
2uxs:B (TYR49) to (ALA80) 2.7A CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE (RV3628) FROM MYCOBACTERIUM TUBERCULOSIS AT PH 7.5 | PPASE, RV3628, HYDROLASE, MAGNESIUM, METAL-BINDING, INORGANIC PYROPHOSPHATASE
2uxs:C (TYR49) to (ALA80) 2.7A CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE (RV3628) FROM MYCOBACTERIUM TUBERCULOSIS AT PH 7.5 | PPASE, RV3628, HYDROLASE, MAGNESIUM, METAL-BINDING, INORGANIC PYROPHOSPHATASE
2f24:A (ARG123) to (VAL159) CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 E111Q MUTANT | SIALIDASE, NEURAMINIDASE, GANGLIOSIDE, DRUG DESIGN, HYDROLASE
2f28:A (ARG123) to (VAL159) CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 Q116E MUTANT | SIALIDASE, NEURAMINIDASE, GANGLIOSIDE, DRUG DESIGN, HYDROLASE
4yz5:B (TYR502) to (GLY537) CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE NANC, IN COMPLEX WITH 3- SIALYLLACTOSE | SIALIDASE, NEURAMINIDASE, BETA-PROPELLER, CBM40, HYDROLASE
4kgq:C (THR33) to (VAL58) CRYSTAL STRUCTURE OF A HUMAN LIGHT LOOP MUTANT IN COMPLEX WITH DCR3 | LIGHT, DCR3, TNF, TNFR, TNF14, STRUCTURAL GENOMICS, PSI-BIOLOGY, NEW HVEM, N-GLYCOSYLATION, MEMBRANE, SECRETED PROTEIN, CYTOKINE, IFN, JELLY-ROLL FOLD, BIND TNF RECEPTOR HVEM AND LTBR, LTBR, PROTEIN STRUCTURE INITIATIVE, ATOMS-TO-ANIMALS: THE IMMUNE FUNCTION NETWORK, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, IMMUNE SYSTEM
2vgl:M (PRO286) to (LYS319) AP2 CLATHRIN ADAPTOR CORE | CYTOPLASMIC VESICLE, ALTERNATIVE SPLICING, ENDOCYTOSIS, LIPID-BINDING, GOLGI APPARATUS, ADAPTOR, MEMBRANE, TRANSPORT, COATED PIT, PHOSPHORYLATION, PROTEIN TRANSPORT
3hrb:A (THR7) to (PRO29) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH SMALL MOLECULE INHIBITOR | P38 MAP KINASE, TRANSFERASE, INHIBITOR COMPLEX, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE
4kns:B (GLU209) to (PRO238) REDUCED CRYSTAL STRUCTURE OF THE NITROSOMONAS EUROPAEA COPPER NITRITE REDUCTASE AT PH 6.5 | NITRITE REDUCTASE, OXIDOREDUCTASE
4kns:C (GLU209) to (PRO238) REDUCED CRYSTAL STRUCTURE OF THE NITROSOMONAS EUROPAEA COPPER NITRITE REDUCTASE AT PH 6.5 | NITRITE REDUCTASE, OXIDOREDUCTASE
4kns:D (GLU209) to (PRO238) REDUCED CRYSTAL STRUCTURE OF THE NITROSOMONAS EUROPAEA COPPER NITRITE REDUCTASE AT PH 6.5 | NITRITE REDUCTASE, OXIDOREDUCTASE
4knt:A (GLU209) to (PRO238) COPPER NITRITE REDUCTASE FROM NITROSOMONAS EUROPAEA PH 8.5 | NITRITE REDUCTASE, OXIDOREDUCTASE
4knt:B (GLU209) to (PRO238) COPPER NITRITE REDUCTASE FROM NITROSOMONAS EUROPAEA PH 8.5 | NITRITE REDUCTASE, OXIDOREDUCTASE
4knt:C (GLU209) to (PRO238) COPPER NITRITE REDUCTASE FROM NITROSOMONAS EUROPAEA PH 8.5 | NITRITE REDUCTASE, OXIDOREDUCTASE
1sg3:A (SER114) to (VAL152) STRUCTURE OF ALLANTOICASE | ALLANTOICASE, JELLY ROLL, HEXAMER, HYDROLASE
1gnm:A (PRO9) to (GLU34) HIV-1 PROTEASE MUTANT WITH VAL 82 REPLACED BY ASP (V82D) COMPLEXED WITH U89360E (INHIBITOR) | ASPARTIC PROTEASE, HIV, MUTANT, INHIBITOR, U-89360E, HYDROLASE (ACID PROTEASE)
1sgu:A (PRO9) to (GLU34) COMPARING THE ACCUMULATION OF ACTIVE SITE AND NON-ACTIVE SITE MUTATIONS IN THE HIV-1 PROTEASE | ACTIVE SITE MUTATIONS, NON-ACTIVE SITE MUTATIONS, INDINAVIR, HIV-1 PROTEASE, HYDROLASE
3i2l:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF A CHEMICALLY SYNTHESIZED [ALLO-ILE50/50']HIV-1 PROTEASE MOLECULE COMPLEXED WITH MVT-101 REDUCED ISOSTERE INHIBITOR | BETA-SHEET, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ksj:A (THR301) to (GLU335) CRYSTAL STRUCTURE OF THE OTU DOMAIN OF GUMBY/FAM105B AT 1.6 ANGSTROM | OTU DOMAIN, DEUBIQUITINASE, UBIQUITIN, HYDROLASE
2vr4:B (THR787) to (ASP812) TRANSITION-STATE MIMICRY IN MANNOSIDE HYDROLYSIS: CHARACTERISATION OF TWENTY SIX INHIBITORS AND INSIGHT INTO BINDING FROM LINEAR FREE ENERGY RELATIONSHIPS AND 3-D STRUCTURE | LINEAR FREE ENERGY RELATIONSHIP, HYDROLASE, TRANSITION STATE MIMIC, MANNOSIDASE, GLYCOSIDE HYDROLASE
3ve0:I (GLU106) to (GLY143) CRYSTAL STRUCTURE OF SUDAN EBOLAVIRUS GLYCOPROTEIN (STRAIN BONIFACE) BOUND TO 16F6 | EBOLA, SUDAN, GLYCOPROTEIN, VIRUS SURFACE, IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX
1heg:E (ARG8) to (GLU34) THE CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF HYDROXYETHYLENE- BASED INHIBITORS BOUND TO HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE SHOW THAT THE INHIBITORS ARE PRESENT IN TWO DISTINCT ORIENTATIONS | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, ACID PROTEINASE
1hiv:A (ARG8) to (GLU34) CRYSTAL STRUCTURE OF A COMPLEX OF HIV-1 PROTEASE WITH A DIHYDROETHYLENE-CONTAINING INHIBITOR: COMPARISONS WITH MOLECULAR MODELING | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1tkr:A (PRO264) to (THR307) HUMAN DIPEPTIDYL PEPTIDASE IV/CD26 INHIBITED WITH DIISOPROPYL FLUOROPHOSPHATE | ALPHA/BETA HYDROLASE, BETA-PROPELLER, HOMODIMER, HYDROLASE
2h7w:B (HIS3) to (GLN25) CRYSTAL STRUCTURE OF CHAGASIN, THE ENDOGENOUS CYSTEINE- PROTEASE INHIBITOR FROM TRYPANOSOMA CRUZI | BETA-STRANDS, IMMUNOGLOBULIN-FOLD, HYDROLASE INHIBITOR
1hxb:A (PRO9) to (GLU34) HIV-1 PROTEINASE COMPLEXED WITH RO 31-8959 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, ASPARTYL PROTEASE
3vye:A (THR18) to (PRO47) HUMAN RENIN IN COMPLEX WITH INHIBITOR 7 | ASPARTYL PROTEASE, RAS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2i07:B (VAL922) to (MET968) HUMAN COMPLEMENT COMPONENT C3B | C3B CONSISTS OF 12 DOMAINS, IMMUNE SYSTEM
2i1a:A (LEU204) to (SER229) A RETROVIRAL PROTEASE-LIKE DOMAIN IN THE EUKARYOTIC PROTEIN DDI1 | ACID PROTEASE FOLD, DIMER, RETROVIRAL PROTEASE DOMAIN, PROTEIN TURNOVER
2i1a:B (LEU204) to (SER229) A RETROVIRAL PROTEASE-LIKE DOMAIN IN THE EUKARYOTIC PROTEIN DDI1 | ACID PROTEASE FOLD, DIMER, RETROVIRAL PROTEASE DOMAIN, PROTEIN TURNOVER
2i1a:C (LEU204) to (SER229) A RETROVIRAL PROTEASE-LIKE DOMAIN IN THE EUKARYOTIC PROTEIN DDI1 | ACID PROTEASE FOLD, DIMER, RETROVIRAL PROTEASE DOMAIN, PROTEIN TURNOVER
2i1a:D (LEU204) to (SER229) A RETROVIRAL PROTEASE-LIKE DOMAIN IN THE EUKARYOTIC PROTEIN DDI1 | ACID PROTEASE FOLD, DIMER, RETROVIRAL PROTEASE DOMAIN, PROTEIN TURNOVER
4m8y:A (PRO9) to (GLU34) GS-8374, A NOVEL PHOSPHONATE-CONTAINING INHIBITOR OF HIV-1 PROTEASE, EFFECTIVELY INHIBITS HIV PR MUTANTS WITH AMINO ACID INSERTIONS | HIV-1 PROTEASE, ASPARTIC PROTEASE, AMINO ACID INSERTION, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
5ab0:C (VAL72) to (HIS111) CRYSTAL STRUCTURE OF AMINOPEPTIDASE ERAP2 WITH LIGAND | AMINOPEPTIDASE, ERAP2, ZINC ION BINDING, ENDOPLASMIC RETICULUM, HYDROLASE, METALLOPROTEASE, L-RAP, ANTIGEN PRESENTATION
4mdr:A (PHE296) to (LEU328) CRYSTAL STRUCTURE OF ADAPTOR PROTEIN COMPLEX 4 (AP-4) MU4 SUBUNIT C- TERMINAL DOMAIN D190A MUTANT, IN COMPLEX WITH A SORTING PEPTIDE FROM THE AMYLOID PRECURSOR PROTEIN (APP) | IMMUNOGLOBULIN-LIKE BETA-SANDWICH, ADAPTOR PROTEIN COMPLEX, GOLGI APPARATUS, SORTING SIGNAL RECOGNITION, ALZHEIMER'S DISEASE, AMYLOID PRECURSOR PROTEIN, PROTEIN TRANSPORT-PROTEIN BINDING COMPLEX
1uyy:A (GLY16) to (TYR42) CARBOHYDRATE BINDING MODULE (CBM6CM-2) FROM CELLVIBRIO MIXTUS LICHENASE 5A IN COMPLEX WITH CELLOTRIOSE | CARBOHYDRATE BINDING MODULE, CBM6, MIXED BETA1, 3-1, 4 LINKED GLUCAN, CELLOTRIOSE
1uyy:B (GLY16) to (TYR42) CARBOHYDRATE BINDING MODULE (CBM6CM-2) FROM CELLVIBRIO MIXTUS LICHENASE 5A IN COMPLEX WITH CELLOTRIOSE | CARBOHYDRATE BINDING MODULE, CBM6, MIXED BETA1, 3-1, 4 LINKED GLUCAN, CELLOTRIOSE
5ahc:A (VAL11) to (GLU34) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN BIS-THF BIS-DIOL
5ahc:B (VAL111) to (GLU134) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN BIS-THF BIS-DIOL
4mzu:A (TRP266) to (ASP294) CRYSTAL STRUCTURE OF FDTD, A BIFUNCTIONAL KETOISOMERASE/N- ACETYLTRANSFERASE FROM SHEWANELLA DENITRIFICANS | BETA-HELIX, CUPIN, KETOISOMERASE, N-ACETYLTRANSFERASE, ACETYL- COENZYME A, DTDP-FUC3N, DTDP-4-KETO-6-DEOXYGLUCOSE, ISOMERASE, TRANSFERASE
4n28:A (ARG3) to (THR27) CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (1 MM CA2+) | DEIMINASE, HYDROLASE
5bnp:B (VAL13) to (ALA34) CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS D68 IN COMPLEX WITH 3'SLN | ENTEROVIRUS, CAPSID, BETA JELLY ROLL, VIRUS, RECEPTOR
4n8p:A (ASP102) to (TYR137) CRYSTAL STRUCTURE OF A STRAND SWAPPED CTLA-4 FROM DUCKBILL PLATYPUS [PSI-NYSGRC-012711] | IMMUNE SYSTEM, ORTHOLOG, IG V-TYPE DOMAIN, STRUCTURAL GENOMICS, PSI- BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC
3jbe:2 (VAL13) to (ALA34) COMPLEX OF POLIOVIRUS WITH VHH PVSS8A | POLIOVIRUS, NANOBODIES, VHH, NEUTRALIZING ANTIBODIES, VIRUS-IMMUNE SYSTEM COMPLEX
1ki0:A (GLU83) to (GLU164) THE X-RAY STRUCTURE OF HUMAN ANGIOSTATIN | KRINGLE DOMAINS, HYDROLASE
2mev:2 (VAL14) to (GLY35) STRUCTURAL REFINEMENT AND ANALYSIS OF MENGO VIRUS | CARDIO PICORNAVIRUS COAT PROTEIN, ICOSAHEDRAL VIRUS
1x6a:A (GLY27) to (VAL60) SOLUTION STRUCTURES OF THE SECOND LIM DOMAIN OF HUMAN LIM- KINASE 2 (LIMK2) | LIM-KINASE 2, ZINC FINGER DOMAIN, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, PROTEIN BINDING
5c7z:A (PRO286) to (LYS319) AP2 MU2 ADAPTIN C-TERMINAL DOMAIN COMPLEXED WITH INTEGRIN ALPHA-4 PEPTIDE | CLATHRIN ADAPTOR, TRANSPORT PROTEIN
5cim:A (PRO88) to (GLY122) STRUCTURE OF MYCOBACTERIUM THERMORESISTIBILE GLGE IN COMPLEX WITH MALTOSE (COCRYSTALLISATION WITH MALTOSE-1-PHOSPHATE) AT 3.32A RESOLUTION | GLGE, MALTOSE, GH13, MALTOSYLTRANSFERASE, TRANSFERASE
4oj6:C (LYS46) to (THR74) CRYSTAL STRUCTURE OF A PUTATIVE TAILSPIKE PROTEIN (TSP1, ORF210) FROM ESCHERICHIA COLI O157:H7 BACTERIOHAGE CBA120; SE-MET PROTEIN | PARALLEL BETA HELIX, PUTATIVE ENDO-GLYCOSIDASE, BACTERIAL POLYSACCHARIDE, PHAGE BASEPLATE, PHAGE TAIL, VIRAL PROTEIN
1lzq:A (ARG8) to (GLU34) CRYSTAL STRUCTURE OF THE COMPLEX OF MUTANT HIV-1 PROTEASE (A71V, V82T, I84V) WITH AN ETHYLENAMINE PEPTIDOMIMETIC INHIBITOR BOC-PHE- PSI[CH2CH2NH]-PHE-GLU-PHE-NH2 | HIV, PEPTIDOMIMETIC, ETHYLENAMINE ISOSTERE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1lzq:B (ARG108) to (GLU134) CRYSTAL STRUCTURE OF THE COMPLEX OF MUTANT HIV-1 PROTEASE (A71V, V82T, I84V) WITH AN ETHYLENAMINE PEPTIDOMIMETIC INHIBITOR BOC-PHE- PSI[CH2CH2NH]-PHE-GLU-PHE-NH2 | HIV, PEPTIDOMIMETIC, ETHYLENAMINE ISOSTERE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4om5:C (ARG1) to (MET26) CRYSTAL STRUCTURE OF CTX A4 FROM TAIWAN COBRA (NAJA NAJA ATRA) | FIVE BETA SHEETS, THREE FUNCTIONAL LOOPS, ENDOCYTOSIS, HEPARIN, HEPARAN SULFATE, TOXIN
2zfy:A (VAL229) to (PRO263) CRYSTAL STRUCTURE OF HUMAN OTUBAIN 1 | OTU, OTUBAIN, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, ALTERNATIVE SPLICING, HYDROLASE, IMMUNE RESPONSE, PHOSPHOPROTEIN, PROTEASE, THIOL PROTEASE, UBL CONJUGATION PATHWAY
3kdc:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, L33I, L63I) IN COMPLEX WITH KNI-10074 | VIRAL PROTEIN, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3kfp:A (VAL11) to (GLU34) HIV PROTEASE (PR) WITH INHIBITOR TL-3 BOUND, AND DMSOS IN EXO SITE | HIV-1, PROTEASE, EXO SITE, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1m9z:A (ILE99) to (SER127) CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN | THREE FINGER TOXIN FOLD, HORMONE-GROWTH FACTOR COMPLEX
3a29:A (CYS92) to (PHE117) CRYSTAL STRUCTURE OF HUMAN LIVER FBPASE IN COMPLEX WITH TRICYCLIC INHIBITOR | HYDROLASE, ALLOSTERIC ENZYME, CARBOHYDRATE METABOLISM, DISEASE MUTATION, GLUCONEOGENESIS, MAGNESIUM, METAL- BINDING, POLYMORPHISM
1yjl:A (PRO199) to (PHE237) REDUCED PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE IN A NEW CRYSTAL FORM | MONOOXYGENASE, BIOACTIVE PEPTIDE ACTIVATION, COPPER, ASCORBATE, OXIDOREDUCTASE
1n1m:A (THR265) to (THR307) HUMAN DIPEPTIDYL PEPTIDASE IV/CD26 IN COMPLEX WITH AN INHIBITOR | ALPHA/BETA, BETA-PROPELLER, DIMER, HYDROLASE
1yu4:B (THR274) to (ASN311) MAJOR TROPISM DETERMINANT U1 VARIANT | C-TYPE LECTIN, BETA SANDWICH, BETA PRISM, VARIABILITY, DIVERSITY-GENERATING RETROELEMENT, VIRAL PROTEIN
5dm7:1 (ILE9) to (LYS38) CRYSTAL STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH HYGROMYCIN A | PROTEIN SYNTHESIS, PEPTIDYLTRANSFERASE, ANTIBIOTIC, AMINOCYCLITOL, RIBOSOME
3l8q:C (THR176) to (ASP212) STRUCTURE ANALYSIS OF THE TYPE II COHESIN DYAD FROM THE ADAPTOR SCAA SCAFFOLDIN OF ACETIVIBRIO CELLULOLYTICUS | DOCKERIN-BINDING MODULE, PROTEIN-PROTEIN INTERACTIONS, LINKER SEGMENT, SCAFFOLDIN ARRANGEMENT, BETA SANDWICH, ALPHA HELIX, BETA FLAPS, STRUCTURAL PROTEIN, PROTEIN BINDING
3l8q:D (THR176) to (ASP212) STRUCTURE ANALYSIS OF THE TYPE II COHESIN DYAD FROM THE ADAPTOR SCAA SCAFFOLDIN OF ACETIVIBRIO CELLULOLYTICUS | DOCKERIN-BINDING MODULE, PROTEIN-PROTEIN INTERACTIONS, LINKER SEGMENT, SCAFFOLDIN ARRANGEMENT, BETA SANDWICH, ALPHA HELIX, BETA FLAPS, STRUCTURAL PROTEIN, PROTEIN BINDING
3ak5:A (GLY418) to (GLY439) HEMOGLOBIN PROTEASE (HBP) PASSENGER MISSING DOMAIN-2 | AUTOTRANSPORTER, BETA HELIX, MUTANT, HYDROLASE
3ak5:B (GLY418) to (GLY439) HEMOGLOBIN PROTEASE (HBP) PASSENGER MISSING DOMAIN-2 | AUTOTRANSPORTER, BETA HELIX, MUTANT, HYDROLASE
3ak5:C (ASP419) to (GLY439) HEMOGLOBIN PROTEASE (HBP) PASSENGER MISSING DOMAIN-2 | AUTOTRANSPORTER, BETA HELIX, MUTANT, HYDROLASE
3ak5:C (HIS1006) to (GLY1048) HEMOGLOBIN PROTEASE (HBP) PASSENGER MISSING DOMAIN-2 | AUTOTRANSPORTER, BETA HELIX, MUTANT, HYDROLASE
3ak5:D (ASP419) to (GLY439) HEMOGLOBIN PROTEASE (HBP) PASSENGER MISSING DOMAIN-2 | AUTOTRANSPORTER, BETA HELIX, MUTANT, HYDROLASE
1zpk:A (ARG8) to (GLU34) CRYSTAL STRUCTURE OF THE COMPLEX OF MUTANT HIV-1 PROTEASE (A71V, V82T, I84V) WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR BOC-PHE- PSI[R-CH(OH)CH2NH]-PHE-GLU-PHE-NH2 | HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1zpk:B (VAL111) to (GLU134) CRYSTAL STRUCTURE OF THE COMPLEX OF MUTANT HIV-1 PROTEASE (A71V, V82T, I84V) WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR BOC-PHE- PSI[R-CH(OH)CH2NH]-PHE-GLU-PHE-NH2 | HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3m5b:A (ASP30) to (GLU64) CRYSTAL STRUCTURE OF THE BTB DOMAIN FROM FAZF/ZBTB32 | BTB DOMAIN, POZ DOMAIN, BTB/POZ DOMAIN, ZBTB32, ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 32, FANCONI ANEMIA ZINC FINGER PROTEIN, FAXF, ROG, TZFP, ZNF538, TESTIS ZINC FINGER PROTEIN, FANCC- INTERACTING PROTEIN, TRANSCRIPTION REGULATOR, ALPHA/BETA PROTEIN, PROTEIN-PROTEIN INTERACTION DOMAIN, ZINC-FINGER PROTEIN, DNA- BINDING, METAL-BINDING, NUCLEUS, REPRESSOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC-FINGER, DNA BINDING PROTEIN, FAZF
3m5b:B (ASP30) to (GLU64) CRYSTAL STRUCTURE OF THE BTB DOMAIN FROM FAZF/ZBTB32 | BTB DOMAIN, POZ DOMAIN, BTB/POZ DOMAIN, ZBTB32, ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 32, FANCONI ANEMIA ZINC FINGER PROTEIN, FAXF, ROG, TZFP, ZNF538, TESTIS ZINC FINGER PROTEIN, FANCC- INTERACTING PROTEIN, TRANSCRIPTION REGULATOR, ALPHA/BETA PROTEIN, PROTEIN-PROTEIN INTERACTION DOMAIN, ZINC-FINGER PROTEIN, DNA- BINDING, METAL-BINDING, NUCLEUS, REPRESSOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC-FINGER, DNA BINDING PROTEIN, FAZF
3mv1:1 (PHE626) to (ALA657) E.COLI (LACZ) BETA-GALACTOSIDASE (R599A) IN COMPLEX WITH GUANIDINIUM | ARG-599-ALA, BETA-GALACTOSIDASE, HYDROLASE TIM BARREL(ALPHA/BETA BARREL), JELLY-ROLL BARREL, IMMUNOGLOBULIN BETA SUPERSANDWHICH, GLYCOSIDASE, HYDROLASE
4bq5:A (ALA65) to (PRO101) STRUCTURAL ANALYSIS OF AN EXO-BETA-AGARASE | HYDROLASE
3c9a:A (CYS359) to (CYS388) HIGH RESOLUTION CRYSTAL STRUCTURE OF ARGOS BOUND TO THE EGF DOMAIN OF SPITZ | ARGOS, SPITZ, EGF, EGFR INHIBITOR, INHIBITOR, DEVELOPMENTAL PROTEIN, GLYCOPROTEIN, SECRETED, SENSORY TRANSDUCTION, VISION, DIFFERENTIATION, EGF-LIKE DOMAIN, ENDOPLASMIC RETICULUM, GOLGI APPARATUS, MEMBRANE, NEUROGENESIS, TRANSMEMBRANE, HORMONE/SIGNALING PROTEIN COMPLEX
4c0y:B (VAL13) to (GLY34) CRYO-EM RECONSTRUCTION OF EMPTY ENTEROVIRUS 71 IN COMPLEX WITH A NEUTRALIZING ANTIBODY E18 | VIRUS-IMMUNE SYSTEM COMPLEX, EV71, ANTIBODY, E18, NEUTRALIZING, PATHOGEN
5fms:A (GLU128) to (LYS178) MMIFT52 N-TERMINAL DOMAIN | TRANSPORT PROTEIN, INTRAFLAGELLAR TRANSPORT, IFTB, IFT52, PROTEIN-PROTEIN INTERACTION
3nls:B (ARG8) to (GLU34) CRYSTAL STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH KNI-10772 | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5foa:B (ASN1382) to (PRO1413) CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH DAF (CCP2-4) | LIPID BINDING, COMPLEMENT SYSTEM, IMMUNE SYSTEM, PLASMA PROTEIN, REGULATORS OF COMPLEMENT ACTIVITY, DECAY-ACCELERATING ACTIVITY
5fob:B (MET938) to (GLU992) CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH SMALLPOX INHIBITOR OF COMPLEMENT (SPICE) | LIPID BINDING PROTEIN, COMPLEMENT SYSTEM, IMMUNE SYSTEM, PLASMA PROTEIN, REGULATORS OF COMPLEMENT ACTIVITY, COFACTOR ACTIVITY, DECAY ACCELERATING ACTIVITY, IMMUNE EVASION
3nu3:B (VAL111) to (GLU134) WILD TYPE HIV-1 PROTEASE WITH ANTIVIRAL DRUG AMPRENAVIR | ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3o0l:A (SER93) to (ALA126) CRYSTAL STRUCTURE OF A PFAM DUF1425 FAMILY MEMBER (SHEW_1734) FROM SHEWANELLA SP. PV-4 AT 1.81 A RESOLUTION | PFAM DUF1425 FAMILY MEMBER, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
4cp7:A (VAL11) to (GLU34) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, ENZYME
4cp7:B (VAL111) to (GLU134) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, ENZYME
4cpq:A (VAL11) to (GLU34) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
4cpq:B (VAL111) to (GLU134) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
3o9c:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD20 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3dck:A (THR12) to (GLU34) X-RAY STRUCTURE OF D25N CHEMICAL ANALOGUE OF HIV-1 PROTEASE COMPLEXED WITH KETOMETHYLENE ISOSTERE INHIBITOR | HIV-1 PROTEASE, HOMODIMER, BETA-TURNS, BETA-STRAND, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3dfj:A (GLY240) to (LEU273) CRYSTAL STRUCTURE OF HUMAN PROSTASIN | PROSTASIN, SERINE PROTEASE, GLYCOPROTEIN, HYDROLASE, MEMBRANE, SECRETED, TRANSMEMBRANE, ZYMOGEN
3ok9:A (ARG8) to (GLU34) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE WITH NEW OXATRICYCLIC DESIGNED INHIBITOR GRL-0519A | ASPARTIC ACID PROTEASE, HIV-1 PROTEASE INHIBITOR GRL-0519A, OXATRICYCLIC LIGANDS, MULTIDRUG-RESISTANT HIV STRAINS, WILD-TYPE HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4d9v:A (SER2) to (GLY27) STRUCTURE OF THE TYPE III SECRETION SYSTEM PROTEIN | FHA DOMAIN, TYPE III SECRETION PROTEIN, UNKNOWN FUNCTION
3otp:A (VAL27) to (THR102) CRYSTAL STRUCTURE OF THE DEGP DODECAMER WITH A MODEL SUBSTRATE | TYPSIN-LIKE PROTEASE DOMAIN PDZ DOMAINS, PROTEASE, HYDROLASE
3otp:B (VAL27) to (THR102) CRYSTAL STRUCTURE OF THE DEGP DODECAMER WITH A MODEL SUBSTRATE | TYPSIN-LIKE PROTEASE DOMAIN PDZ DOMAINS, PROTEASE, HYDROLASE
3otp:C (VAL27) to (THR102) CRYSTAL STRUCTURE OF THE DEGP DODECAMER WITH A MODEL SUBSTRATE | TYPSIN-LIKE PROTEASE DOMAIN PDZ DOMAINS, PROTEASE, HYDROLASE
3otp:D (VAL27) to (THR102) CRYSTAL STRUCTURE OF THE DEGP DODECAMER WITH A MODEL SUBSTRATE | TYPSIN-LIKE PROTEASE DOMAIN PDZ DOMAINS, PROTEASE, HYDROLASE
3otp:E (VAL27) to (THR102) CRYSTAL STRUCTURE OF THE DEGP DODECAMER WITH A MODEL SUBSTRATE | TYPSIN-LIKE PROTEASE DOMAIN PDZ DOMAINS, PROTEASE, HYDROLASE
3otp:F (VAL27) to (THR102) CRYSTAL STRUCTURE OF THE DEGP DODECAMER WITH A MODEL SUBSTRATE | TYPSIN-LIKE PROTEASE DOMAIN PDZ DOMAINS, PROTEASE, HYDROLASE
3oxc:A (VAL11) to (GLU34) WILD TYPE HIV-1 PROTEASE WITH ANTIVIRAL DRUG SAQUINAVIR | ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, SAQUINAVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4duw:C (PHE626) to (VAL656) E. COLI (LACZ) BETA-GALACTOSIDASE (G974A) IN COMPLEX WITH ALLOLACTOSE | BI-FUNCTIONAL ENZYME, ALLOLACTOSE SYNTHESIS, TIM BARREL (ALPHA/BETA BARREL), JELLY-ROLL BARREL, IMMUNOGLOBULIN, BETA SUPERSANDWICH, BETA-GALACTOSIDASE, GLYCOSIDASE, HYDROLASE
4e43:B (VAL11) to (GLU34) HIV PROTEASE (PR) DIMER WITH ACETATE IN EXO SITE AND PEPTIDE IN ACTIVE SITE | HIV-1 PROTEASE, EXO SITE, ASPARTYL PROTEASE, FRAGMENT SCREEN, HYDROLASE
5ida:A (LEU75) to (LEU105) CRYSTAL STRUCTURE OF CGL1 FROM CRASSOSTREA GIGAS, MANNOSE-BOUND FORM (CGL1/MAN) | CGL1, LECTIN, CRASSOSTREA GIGAS, N-TYPE, MANNOSE, SUGAR BINDING PROTEIN
5ida:B (GLY76) to (LEU105) CRYSTAL STRUCTURE OF CGL1 FROM CRASSOSTREA GIGAS, MANNOSE-BOUND FORM (CGL1/MAN) | CGL1, LECTIN, CRASSOSTREA GIGAS, N-TYPE, MANNOSE, SUGAR BINDING PROTEIN
5ida:D (LEU75) to (LEU105) CRYSTAL STRUCTURE OF CGL1 FROM CRASSOSTREA GIGAS, MANNOSE-BOUND FORM (CGL1/MAN) | CGL1, LECTIN, CRASSOSTREA GIGAS, N-TYPE, MANNOSE, SUGAR BINDING PROTEIN
4utk:A (GLU6) to (TYR27) XENA - REDUCED - Y183F VARIANT | OXIDOREDUCTASE
4ep3:A (VAL11) to (GLU34) CRYSTAL STRUCTURE OF INACTIVE SINGLE CHAIN WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH THE SUBSTRATE CA-P2 | HIV-1 PROTEASE, SPECIFICITY DESIGN, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE SUBSTRATE COMPLEX
5ivq:B (VAL11) to (GLU34) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH METHYL N-[(1S)-1- BENZHYDRYL-2-(3-MORPHOLIN-4-IUM-2-YLPROPYLAMINO)-2-OXO- ETHYL]CARBAMATE | HIV, PROTEASE, HYDROLASE-INHIBITOR COMPLEX
3qaa:B (VAL111) to (GLU134) HIV-1 WILD TYPE PROTEASE WITH A SUBSTITUTED BIS-TETRAHYDROFURAN INHIBITOR, GRL-044-10A | ASPARTIC ACID PROTEASE, HIV-1 PROTEASE INHIBITOR GRL-044-10A, SUBSTITUTED BIS-TETRAHYDROFURAN INHIBITOR, WILD-TYPE HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4fl4:F (LYS8) to (ASP48) SCAFFOLDIN CONFORMATION AND DYNAMICS REVEALED BY A TERNARY COMPLEX FROM THE CLOSTRIDIUM THERMOCELLUM CELLULOSOME | STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, COHESIN, DOCKERIN, X MODULE, CELL SURFACE, HYDROLASE, PROTEIN BINDING
4fl4:H (ALA18) to (ASP58) SCAFFOLDIN CONFORMATION AND DYNAMICS REVEALED BY A TERNARY COMPLEX FROM THE CLOSTRIDIUM THERMOCELLUM CELLULOSOME | STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, COHESIN, DOCKERIN, X MODULE, CELL SURFACE, HYDROLASE, PROTEIN BINDING
4fl4:L (LEU9) to (ASP48) SCAFFOLDIN CONFORMATION AND DYNAMICS REVEALED BY A TERNARY COMPLEX FROM THE CLOSTRIDIUM THERMOCELLUM CELLULOSOME | STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, COHESIN, DOCKERIN, X MODULE, CELL SURFACE, HYDROLASE, PROTEIN BINDING
5jia:A (TYR65) to (ALA92) THE CRYSTAL STRUCTURE OF IUS-SPRY DOMAIN FROM RANBP10 | BETA SANDWICH, TRANSPORT PROTEIN, RAN-BINDING PROTEIN
5jia:B (TYR65) to (ALA92) THE CRYSTAL STRUCTURE OF IUS-SPRY DOMAIN FROM RANBP10 | BETA SANDWICH, TRANSPORT PROTEIN, RAN-BINDING PROTEIN
5jia:F (TYR65) to (ALA92) THE CRYSTAL STRUCTURE OF IUS-SPRY DOMAIN FROM RANBP10 | BETA SANDWICH, TRANSPORT PROTEIN, RAN-BINDING PROTEIN
5jia:J (TYR65) to (ALA92) THE CRYSTAL STRUCTURE OF IUS-SPRY DOMAIN FROM RANBP10 | BETA SANDWICH, TRANSPORT PROTEIN, RAN-BINDING PROTEIN
5jia:L (TYR65) to (ALA92) THE CRYSTAL STRUCTURE OF IUS-SPRY DOMAIN FROM RANBP10 | BETA SANDWICH, TRANSPORT PROTEIN, RAN-BINDING PROTEIN
5jia:O (TYR65) to (ALA92) THE CRYSTAL STRUCTURE OF IUS-SPRY DOMAIN FROM RANBP10 | BETA SANDWICH, TRANSPORT PROTEIN, RAN-BINDING PROTEIN
5jia:P (TYR65) to (ALA92) THE CRYSTAL STRUCTURE OF IUS-SPRY DOMAIN FROM RANBP10 | BETA SANDWICH, TRANSPORT PROTEIN, RAN-BINDING PROTEIN
5jze:A (ILE117) to (GLY151) ERVE VIRUS VIRAL OTU DOMAIN PROTEASE IN COMPLEX WITH MOUSE ISG15 | VOTU, ISG15, NAIROVIRUS, PROTEASE, HYDROLASE
5lkh:A (GLN1499) to (ASN1533) CRYO-EM STRUCTURE OF THE TC TOXIN TCDA1 IN ITS PORE STATE (OBTAINED BY FLEXIBLE FITTING) | NANODISC, TOXIN, INJECTION, PORE-FORMING
5lkh:B (GLN1499) to (ASN1533) CRYO-EM STRUCTURE OF THE TC TOXIN TCDA1 IN ITS PORE STATE (OBTAINED BY FLEXIBLE FITTING) | NANODISC, TOXIN, INJECTION, PORE-FORMING
5lkh:C (GLN1499) to (ASN1533) CRYO-EM STRUCTURE OF THE TC TOXIN TCDA1 IN ITS PORE STATE (OBTAINED BY FLEXIBLE FITTING) | NANODISC, TOXIN, INJECTION, PORE-FORMING
5lkh:D (GLN1499) to (ASN1533) CRYO-EM STRUCTURE OF THE TC TOXIN TCDA1 IN ITS PORE STATE (OBTAINED BY FLEXIBLE FITTING) | NANODISC, TOXIN, INJECTION, PORE-FORMING
5lkh:E (GLN1499) to (ASN1533) CRYO-EM STRUCTURE OF THE TC TOXIN TCDA1 IN ITS PORE STATE (OBTAINED BY FLEXIBLE FITTING) | NANODISC, TOXIN, INJECTION, PORE-FORMING