4we1:A (HIS361) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH 5-(2- (2-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)ETHOXY)PHENOXY)-2- NAPHTHONITRILE (JLJ600) | POLYMERASE, TRANSFERASE, HYDROLASE, RNASEH, RNASE
1nb3:D (GLN64) to (GLU83) CRYSTAL STRUCTURE OF STEFIN A IN COMPLEX WITH CATHEPSIN H: N-TERMINAL RESIDUES OF INHIBITORS CAN ADAPT TO THE ACTIVE SITES OF ENDO-AND EXOPEPTIDASES | CYSTEINE PROTEINASE, AMINOPEPTIDASE, CYSTATIN, ENZYME-INHIBITOR COMPLEX, HYDROLASE
1a55:A (LYS215) to (ASN243) PHOSPHATE-BINDING PROTEIN MUTANT A197C | PHOSPHOTRANSFERASE, TRANSPORT
4gv7:A (ILE895) to (GLY922) HUMAN ARTD1 (PARP1) - CATALYTIC DOMAIN IN COMPLEX WITH INHIBITOR ME0328 | NAD, ADP-RIBOSE, PARP1, ARTD1, ARTD TRANSFERASE DOMAIN, ADP- RIBOSYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, ADP-RIBOSE TRANSFERASE
1ndf:B (PRO378) to (THR413) CARNITINE ACETYLTRANSFERASE IN COMPLEX WITH CARNITINE | ACETYL TRANSFER, COA, COENZYME A,, TRANSFERASE
1ndi:B (LEU381) to (THR413) CARNITINE ACETYLTRANSFERASE IN COMPLEX WITH COA | ACETYL TRANSFER, COA, COENZYME A, TRANSFERASE
1nfg:A (LEU126) to (PHE150) STRUCTURE OF D-HYDANTOINASE | TIM BARREL, HYDROLASE
1nfg:B (LEU126) to (PHE150) STRUCTURE OF D-HYDANTOINASE | TIM BARREL, HYDROLASE
1nfg:C (LEU126) to (PHE150) STRUCTURE OF D-HYDANTOINASE | TIM BARREL, HYDROLASE
1nfg:D (LEU126) to (PHE150) STRUCTURE OF D-HYDANTOINASE | TIM BARREL, HYDROLASE
2apr:A (ASP120) to (LYS160) STRUCTURE AND REFINEMENT AT 1.8 ANGSTROMS RESOLUTION OF THE ASPARTIC PROTEINASE FROM RHIZOPUS CHINENSIS | HYDROLASE (ASPARTIC PROTEINASE)
2ary:B (PHE334) to (LEU353) CATALYTIC DOMAIN OF HUMAN CALPAIN-1 | CYSTEINE PROTEASE, PAPAIN, CALCIUM-DEPENDENT, THIOL PROTEASE, HYDROLASE,STRUCTURAL GENOMICS CONSORTIUM, SGC
4wiw:B (GLU637) to (ALA667) CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF PUTATIVE CHITINASE FROM DESULFITOBACTERIUM HAFNIENSE DCB-2 | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, GLYCOSIDE HYDROLASE FAMILY 18, HYDROLASE
4wiw:C (GLU637) to (ALA667) CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF PUTATIVE CHITINASE FROM DESULFITOBACTERIUM HAFNIENSE DCB-2 | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, GLYCOSIDE HYDROLASE FAMILY 18, HYDROLASE
1adi:A (ARG304) to (LYS331) STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE AT PH 6.5 AND 25 DEGREES CELSIUS | PURINE NUCLEOTIDE BIOSYNTHESIS, LIGASE, GTP-HYDROLYZING ENZYME
3ef9:A (ARG215) to (LEU252) REPLACEMENT OF VAL3 IN HUMAN THYMIDYLATE SYNTHASE AFFECTS ITS KINETIC PROPERTIES AND INTRACELLULAR STABILITY | TRANSFERASE, METHYLTRANSFERASE, NUCLEOTIDE BIOSYNTHESIS
4gzz:D (ARG1164) to (ARG1189) CRYSTAL STRUCTURES OF BACTERIAL RNA POLYMERASE PAUSED ELONGATION COMPLEXES | RNA POLYMERASE, TRANSCRIPTION, PAUSED TRANSCRIPTION ELONGATION COMPLEX, TRANSCRIPTIONAL PAUSING, DNA DIRECTED RNA TRANSCRIPTION', TRANSCRIPTION-DNA-RNA HYBRID COMPLEX
3rxy:A (ALA0) to (VAL30) CRYSTAL STRUCTURE OF NIF3 SUPERFAMILY PROTEIN FROM SPHAEROBACTER THERMOPHILUS | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, NIF3 SUPERFAMILY, UNKNOWN FUNCTION
3rxy:B (ALA0) to (VAL30) CRYSTAL STRUCTURE OF NIF3 SUPERFAMILY PROTEIN FROM SPHAEROBACTER THERMOPHILUS | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, NIF3 SUPERFAMILY, UNKNOWN FUNCTION
4h4o:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH (E)-3-(3-(2-(2-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)ETHOXY)- 4- FLUOROPHENOXY)-5-FLUOROPHENYL)ACRYLONITRILE (JLJ506), A NON- NUCLEOSIDE INHIBITOR | POLYMERASE, TRANSFERASE, HYDROLASE/INHIBITOR, RNASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4ws9:D (ASN3) to (LYS25) CRYSTAL STRUCTURE OF SMAT N159G FROM SULFOLOBUS SOLFATARICUS | TRANSFERASE, S-ADENOSYLMETHIONINE
4ws9:K (ASN3) to (LYS25) CRYSTAL STRUCTURE OF SMAT N159G FROM SULFOLOBUS SOLFATARICUS | TRANSFERASE, S-ADENOSYLMETHIONINE
2ox4:B (GLY178) to (ASN214) CRYSTAL STRUCTURE OF PUTATIVE DEHYDRATASE FROM ZYMOMONAS MOBILIS ZM4 | ENOLASE, DEHYDRATASE, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NYSGRC, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, ISOMERASE
2ox4:C (GLY178) to (ASN214) CRYSTAL STRUCTURE OF PUTATIVE DEHYDRATASE FROM ZYMOMONAS MOBILIS ZM4 | ENOLASE, DEHYDRATASE, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NYSGRC, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, ISOMERASE
3eol:A (GLY190) to (THR223) 2.0A CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BRUCELLA MELITENSIS (P43212) | BRUCELLA, MELITENSIS, ISOCITRATE, LYASE, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID
2p1m:B (GLY142) to (GLU165) TIR1-ASK1 COMPLEX STRUCTURE | F-BOX, LEUCINE RICH REPEAT, SIGNALING PROTEIN
2p1q:B (MET115) to (LEU137) MECHANISM OF AUXIN PERCEPTION BY THE TIR1 UBIQUITIN LIGASE | F-BOX, LEUCINE RICH REPEAT, SIGNALING PROTEIN
1b7b:A (ALA205) to (GLY230) CARBAMATE KINASE FROM ENTEROCOCCUS FAECALIS | PHOSPHOTRANSFERASE, ARGININE CATABOLISM, ATP SYNTHESYS, ACYLPHOSPHATE-MAKING ENZYMES, OPEN ALPHA/BETA SHEET
1b7b:B (ALA205) to (LEU228) CARBAMATE KINASE FROM ENTEROCOCCUS FAECALIS | PHOSPHOTRANSFERASE, ARGININE CATABOLISM, ATP SYNTHESYS, ACYLPHOSPHATE-MAKING ENZYMES, OPEN ALPHA/BETA SHEET
2pc9:C (LYS57) to (GLY107) CRYSTAL STRUCTURE OF ATP-DEPENDENT PHOSPHOENOLPYRUVATE CARBOXYKINASE FROM THERMUS THERMOPHILUS HB8 | PHOSPHOENOLPYRUVATE CARBOXYKINASE, ADENOSINE TRIPHOSPHATE, THERMUS THERMOPHILUS HB8, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LYASE
2pc9:D (LYS57) to (GLY107) CRYSTAL STRUCTURE OF ATP-DEPENDENT PHOSPHOENOLPYRUVATE CARBOXYKINASE FROM THERMUS THERMOPHILUS HB8 | PHOSPHOENOLPYRUVATE CARBOXYKINASE, ADENOSINE TRIPHOSPHATE, THERMUS THERMOPHILUS HB8, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LYASE
3f03:K (THR147) to (HIS181) CRYSTAL STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE COMPLEX WITH 1-NITROCYCLOHEXENE | ASYMMETRIC HYDROGENATIO, BIOREDUCTION, BIOCATALYSIS, NITROALKENES, PENTAERYTHRITOL TETRANITRATE REDUCTASE, STEREO-CONTROL, OXIDOREDUCTASE
1bml:D (PRO71) to (ASP102) COMPLEX OF THE CATALYTIC DOMAIN OF HUMAN PLASMIN AND STREPTOKINASE | HUMAN PLASMIN, STREPTOKINASE, BLOOD CLOTTING
1bml:D (GLY191) to (GLU218) COMPLEX OF THE CATALYTIC DOMAIN OF HUMAN PLASMIN AND STREPTOKINASE | HUMAN PLASMIN, STREPTOKINASE, BLOOD CLOTTING
1bol:A (GLY159) to (SER183) THE CRYSTAL STRUCTURE OF RIBONUCLEASE RH FROM RHIZOPUS NIVEUS AT 2.0 A RESOLUTION | RIBONUCLEASES, HYDROLASE
2bo9:B (MET1) to (VAL34) HUMAN CARBOXYPEPTIDASE A4 IN COMPLEX WITH HUMAN LATEXIN. | METALLOCARBOXYPEPTIDASE, X-RAY CRYSTAL STRUCTURE, ENDOGENOUS PROTEIN INHIBITOR, LATEXIN, METALLOPROTEASE CARBOXYPEPTIDASE, HYDROLASE
2bo9:D (MET1) to (VAL34) HUMAN CARBOXYPEPTIDASE A4 IN COMPLEX WITH HUMAN LATEXIN. | METALLOCARBOXYPEPTIDASE, X-RAY CRYSTAL STRUCTURE, ENDOGENOUS PROTEIN INHIBITOR, LATEXIN, METALLOPROTEASE CARBOXYPEPTIDASE, HYDROLASE
1bq3:A (GLU147) to (ALA179) SACCHAROMYCES CEREVISIAE PHOSPHOGLYCERATE MUTASE IN COMPLEX WITH INOSITOL HEXAKISPHOSPHATE | ISOMERASE, TRANSFERASE (PHOSPHORYL), GLYCOLYTIC ENZYME
4hpm:A (GLY1682) to (SER1708) PCGF1 UB FOLD (RAWUL)/BCORL1 PUFD COMPLEX | POLYCOMB, BCORL1, PCGF1, RAWUL, NSPC1, E3-LIGASE, CHROMOSOMAL PROTEIN, TRANSCRIPTION REGULATION, CHROMATIN REGULATOR, TRANSCRIPTION REPRESSOR, LIGASE, METAL-BINDING, NUCLEUS, REPRESSOR, TRANSCRIPTION, UBL CONJUGATION PATHWAY, ZINC-FINGER
3faw:A (GLY769) to (MET803) CRYSTAL STRUCTURE OF THE GROUP B STREPTOCOCCUS PULLULANASE SAP | TIM BARREL, BETA BARREL, HYDROLASE, CELL WALL, PEPTIDOGLYCAN-ANCHOR, SECRETED
1obh:A (SER608) to (PRO624) LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A PRE-TRANSFER EDITING SUBSTRATE ANALOGUE IN BOTH SYNTHETIC ACTIVE SITE AND EDITING SITE | SYNTHETASE, AMINOACYL-TRNA SYNTHETASE, CLASS I AMINOACYL-TRNA SYNTHETASE, ATP + L-LEUCINE + TRNA (LEU) -> AMP + PPI L- LEUCYL-TRNA(LEU)
2pgo:A (ALA2) to (GLY24) THE CRYSTAL STRUCTURE OF FAD AND THDP DEPENDENT CYCLOHEXANE-1,2-DIONE HYDROLASE (CDH) FROM AZOARCUS SP. STRAIN 22LIN | THREE ALPHA/BETA DOMAINS, HYDROLASE
2pgo:B (ALA2) to (GLY24) THE CRYSTAL STRUCTURE OF FAD AND THDP DEPENDENT CYCLOHEXANE-1,2-DIONE HYDROLASE (CDH) FROM AZOARCUS SP. STRAIN 22LIN | THREE ALPHA/BETA DOMAINS, HYDROLASE
2pgn:A (ALA2) to (GLY24) THE CRYSTAL STRUCTURE OF FAD AND THDP-DEPENDENT CYCLOHEXANE-1,2-DIONE HYDROLASE IN COMPLEX WITH CYCLOHEXANE-1,2-DIONE | THREE ALPHA/BETA DOMAINS, HYDROLASE
2pgn:B (ALA2) to (GLY24) THE CRYSTAL STRUCTURE OF FAD AND THDP-DEPENDENT CYCLOHEXANE-1,2-DIONE HYDROLASE IN COMPLEX WITH CYCLOHEXANE-1,2-DIONE | THREE ALPHA/BETA DOMAINS, HYDROLASE
1of3:A (ALA8) to (GLN29) STRUCTURAL AND THERMODYNAMIC DISSECTION OF SPECIFIC MANNAN RECOGNITION BY A CARBOHYDRATE-BINDING MODULE, TMCBM27 | HYDROLASE/CARBOHYDRATE BINDING, MANNAN BINDING, CARBOHYDRATE BINDING MODULE, POLYSACCHARIDE DEGRADATION, TMCBM27, HYDROLASE
1of3:B (ALA8) to (GLN29) STRUCTURAL AND THERMODYNAMIC DISSECTION OF SPECIFIC MANNAN RECOGNITION BY A CARBOHYDRATE-BINDING MODULE, TMCBM27 | HYDROLASE/CARBOHYDRATE BINDING, MANNAN BINDING, CARBOHYDRATE BINDING MODULE, POLYSACCHARIDE DEGRADATION, TMCBM27, HYDROLASE
1of4:A (ALA8) to (GLN29) STRUCTURAL AND THERMODYNAMIC DISSECTION OF SPECIFIC MANNAN RECOGNITION BY A CARBOHYDRATE-BINDING MODULE, TMCBM27 | HYDROLASE/CARBOHYDRATE BINDING, MANNAN BINDING, CARBOHYDRATE BINDING MODULE, POLYSACCHARIDE DEGRADATION, HYDROLASE
3fey:A (PRO222) to (HIS248) CRYSTAL STRUCTURE OF THE CBC-IMPORTIN ALPHA COMPLEX. | CAP BINDING COMPLEX, IMPORTIN ALPHA, NUCLEAR TRANSPORT, MRNA TRANSPORT, NUCLEUS, PHOSPHOPROTEIN, RNA-BINDING, HOST-VIRUS INTERACTION, TRANSLATION, PROTEIN TRANSPORT
3ff6:C (LYS2120) to (PHE2154) HUMAN ACC2 CT DOMAIN WITH CP-640186 | ACETYL COA CARBOXYLASE, ACC2, ACC, METABOLIC DISORDER, FATTY ACID METABOLISM, ATP-BINDING, BIOTIN, FATTY ACID BIOSYNTHESIS, LIGASE, LIPID SYNTHESIS, MANGANESE, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN
4hyf:A (ILE954) to (LEU995) STRUCTURAL BASIS AND SAR FOR OD 270, A LEAD STAGE 1,2,4-TRIAZOLE BASED SPECIFIC TANKYRASE1/2 INHIBITOR | CATALYTIC FRAGMENT, PARP, ADP-RIBOSYLATION, ANK REPEAT, CHROMOSOMAL PROTEIN,, CHROMOSOMAL PROTEIN, GLYCOSYLTRANSFERASE,, PHOSPHORYLATION, TELOMERE, TRANSFERASE, TRANSLOCATION, TRANSPORT, WNT-SIGNALLING, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4hyf:B (ILE954) to (LEU995) STRUCTURAL BASIS AND SAR FOR OD 270, A LEAD STAGE 1,2,4-TRIAZOLE BASED SPECIFIC TANKYRASE1/2 INHIBITOR | CATALYTIC FRAGMENT, PARP, ADP-RIBOSYLATION, ANK REPEAT, CHROMOSOMAL PROTEIN,, CHROMOSOMAL PROTEIN, GLYCOSYLTRANSFERASE,, PHOSPHORYLATION, TELOMERE, TRANSFERASE, TRANSLOCATION, TRANSPORT, WNT-SIGNALLING, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1c4p:B (ASP192) to (GLU218) BETA DOMAIN OF STREPTOKINASE | PLASMINOGEN ACTIVATOR, BLOOD CLOTTING
1c4p:C (ASP192) to (GLU218) BETA DOMAIN OF STREPTOKINASE | PLASMINOGEN ACTIVATOR, BLOOD CLOTTING
1c4p:D (ASP192) to (GLU218) BETA DOMAIN OF STREPTOKINASE | PLASMINOGEN ACTIVATOR, BLOOD CLOTTING
1ogs:A (SER351) to (TRP381) HUMAN ACID-BETA-GLUCOSIDASE | HYDROLASE, GAUCHER DISEASE, GLUCOSIDASE, GLUCOCEREBROSIDASE, CEREZYME HYDROLASE, GLYCOSIDASE, SPHINGOLIPID METABOLISM, GLYCOPROTE LYSOSOME, MEMBRANE, SIGNAL, DISEASE MUTATI POLYMORPHISM, ALTERNATIVE INITIATION, PHARMACEUTICAL, ISRAEL STRUCTURAL PROTEOMICS CENTER, ISPC, STRUCTURAL GENOMICS
1ogs:B (SER351) to (TRP381) HUMAN ACID-BETA-GLUCOSIDASE | HYDROLASE, GAUCHER DISEASE, GLUCOSIDASE, GLUCOCEREBROSIDASE, CEREZYME HYDROLASE, GLYCOSIDASE, SPHINGOLIPID METABOLISM, GLYCOPROTE LYSOSOME, MEMBRANE, SIGNAL, DISEASE MUTATI POLYMORPHISM, ALTERNATIVE INITIATION, PHARMACEUTICAL, ISRAEL STRUCTURAL PROTEOMICS CENTER, ISPC, STRUCTURAL GENOMICS
4xhj:A (GLU386) to (ASP424) GHGL OF VARICELLA-ZOSTER VIRUS IN COMPLEX WITH HUMAN NEUTRALIZING ANTIBODIES. | COMPLEX, NEUTRALIZATION EPITOPES, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
4xhj:E (GLU386) to (ASP424) GHGL OF VARICELLA-ZOSTER VIRUS IN COMPLEX WITH HUMAN NEUTRALIZING ANTIBODIES. | COMPLEX, NEUTRALIZATION EPITOPES, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
1oib:A (LYS215) to (THR242) PHOSPHATE-BINDING PROTEIN MUTANT T141D | PHOSPHATE TRANSPORT
1oib:B (LYS215) to (THR242) PHOSPHATE-BINDING PROTEIN MUTANT T141D | PHOSPHATE TRANSPORT
4i7f:A (ALA360) to (LYS390) HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH A PHOSPHONATE ANALOG OF NEVIRAPINE | NNRTI, HIV, REVERSE TRANSCRIPTASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4xln:D (GLY1163) to (ARG1189) CRYSTAL STRUCTURE OF T. AQUATICUS TRANSCRIPTION INITIATION COMPLEX CONTAINING BUBBLE PROMOTER AND RNA | PROTEIN-DNA COMPLEX, BACTERIAL TRANSCRIPTION INITIATION COMPLEX, TRANSCRIPTION-DNA-RNA COMPLEX
4xln:J (GLY1163) to (ARG1189) CRYSTAL STRUCTURE OF T. AQUATICUS TRANSCRIPTION INITIATION COMPLEX CONTAINING BUBBLE PROMOTER AND RNA | PROTEIN-DNA COMPLEX, BACTERIAL TRANSCRIPTION INITIATION COMPLEX, TRANSCRIPTION-DNA-RNA COMPLEX
2q2x:A (GLY113) to (PHE131) CRYSTAL STRUCTURE OF THE ECH2 DECARBOXYLASE DOMAIN OF CURF FROM LYNGBYA MAJUSCULA | CROTONASE, LYASE
4id5:A (ALA360) to (LYS390) HIV-1 REVERSE TRANSCRIPTASE WITH BOUND FRAGMENT AT THE RNASE H PRIMER GRIP SITE | RNA-DIRECTED DNA POLYMERASE, DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MULTIFUNCTIONAL ENZYME, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2c89:A (GLY171) to (ALA195) STRUCTURE OF THE WILD-TYPE C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I) | C3 EXOENZYME, ARTT MOTIF, BACTERIAL TOXINS, TRANSFERASE, GLYCOSYLTRANSFERASE
2c8c:B (GLY171) to (LYS196) STRUCTURE OF THE ARTT MOTIF Q212A MUTANT C3BOT1 EXOENZYME (NAD-BOUND STATE, CRYSTAL FORM I) | C3 EXOENZYME, ARTT MOTIF, BACTERIAL TOXINS, GLYCOSYLTRANSFERASE, TRANSFERASE
2c8d:A (GLY171) to (LYS196) STRUCTURE OF THE ARTT MOTIF Q212A MUTANT C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I) | C3 EXOENZYME, ARTT MOTIF, BACTERIAL TOXINS, GLYCOSYLTRANSFERASE, TRANSFERASE
2c8d:B (GLY171) to (ALA195) STRUCTURE OF THE ARTT MOTIF Q212A MUTANT C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I) | C3 EXOENZYME, ARTT MOTIF, BACTERIAL TOXINS, GLYCOSYLTRANSFERASE, TRANSFERASE
2c8e:E (GLY171) to (ALA195) STRUCTURE OF THE ARTT MOTIF E214N MUTANT C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM III) | C3 EXOENZYME, ARTT MOTIF, BACTERIAL TOXINS, TRANSFERASE, GLYCOSYLTRANSFERASE
2c8g:A (GLY171) to (LYS196) STRUCTURE OF THE PN LOOP Q182A MUTANT C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I) | C3 EXOENZYME, ARTT MOTIF, ADP-RIBOSYLTRANSFERASE, BACTERIAL TOXINS, TRANSFERASE, GLYCOSYLTRANSFERASE
2c8g:B (GLY171) to (LYS196) STRUCTURE OF THE PN LOOP Q182A MUTANT C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I) | C3 EXOENZYME, ARTT MOTIF, ADP-RIBOSYLTRANSFERASE, BACTERIAL TOXINS, TRANSFERASE, GLYCOSYLTRANSFERASE
2c8g:D (GLY171) to (LYS196) STRUCTURE OF THE PN LOOP Q182A MUTANT C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I) | C3 EXOENZYME, ARTT MOTIF, ADP-RIBOSYLTRANSFERASE, BACTERIAL TOXINS, TRANSFERASE, GLYCOSYLTRANSFERASE
2q5l:B (PRO247) to (GLY277) X-RAY STRUCTURE OF PHENYLPYRUVATE DECARBOXYLASE IN COMPLEX WITH 2-(1- HYDROXYETHYL)-3-DEAZA-THDP | THIAMINE DIPHOSPHATE, ASYMMETRIC DIMER OF DIMERS, OPEN ACTIVE SITE LOOP, COVALENT INTERMEDIATE ANALOGUE, LYASE
2ca6:B (ASN42) to (PHE67) MIRAS STRUCTURE DETERMINATION FROM HEMIHEDRALLY TWINNED CRYSTALS | GAP, GTPASE ACTIVATION, GTPASE-ACTIVATING PROTEIN, HEMIHEDRAL TWINNING, LEUCINE-RICH REPEAT PROTEIN, LRR, MEROHEDRAL TWINNING, MEROHEDRY, RANGAP, RNA1P, SIGNALING PROTEIN, SIGNALING ACTIVATOR, NUCLEAR TRANSPORT, SIGNALING REGULATOR
4ihh:E (ALA2) to (GLY19) CHASING ACYL CARRIER PROTEIN THROUGH A CATALYTIC CYCLE OF LIPID A PRODUCTION | ACYL CARRIER PROTEIN, LEFT HANDED BETA HELIX, LPXD, ACYLTRANSFERASE, LIPID A, PROTEIN-PROTEIN COMPLEX, ACP RECOGNITION DOMAIN, ACP MEDIATED PRODUCT RELEASE, TRANSFERASE-LIPID BINDING PROTEIN COMPLEX
2qf2:A (MET173) to (ILE190) RAT CYTOSOLIC PEPCK IN COMPLEX WITH OXALOACETIC ACID AND GDP. | PEPCK, PHOSPHOENOLPYRUVATE CARBOXYKINASE, KINASE, OAA, GDP, GLUCONEOGENESIS, LYASE
1dd1:B (VAL437) to (ALA486) CRYSTAL STRUCTURE ANALYSIS OF THE SMAD4 ACTIVE FRAGMENT | B-SHEET SANDWICH HELIX-TURN-HELIX, SIGNALING PROTEIN
2qgf:C (GLU50) to (GLY72) STRUCTURE OF REGULATORY CHAIN MUTANT H20A OF ASPARATE TRANSCARBAMOYLASE FROM E. COLI | ALLOSTERIC ENZYME REGULATORY CHAIN MUTATION, HETEROTROPIC REGULATION, TRANSFERASE-TRANSFERASE REGULATOR COMPLEX
1pbp:A (LYS215) to (ASN243) FINE TUNING OF THE SPECIFICITY OF THE PERIPLASMIC PHOSPHATE TRANSPORT RECEPTOR: SITE-DIRECTED MUTAGENESIS, LIGAND BINDING, AND CRYSTALLOGRAPHIC STUDIES | PHOSPHATE TRANSPORT
1pc3:A (GLY248) to (ASP279) CRYSTAL STRUCTURE OF THE EXTRACELLULAR PHOSPHATE ABC TRANSPORT RECEPTOR (PSTS-1) AND IMMUNODOMINANT ANTIGEN OF M. TUBERCULOSIS. | PHOSPHATE TRANSPORT RECEPTOR, IMMONODOMINANT ANTIGEN, MYCOBACTERIUM TUBERCULOSIS, ION-DIPOLE INTERACTIONS, ELECTROSTATICS, TRANSPORT PROTEIN
1dj2:A (GLY90) to (SER119) STRUCTURES OF ADENYLOSUCCINATE SYNTHETASE FROM TRITICUM AESTIVUM AND ARABIDOPSIS THALIANA | GDP, LIGASE
3gb0:A (PRO288) to (HIS316) CRYSTAL STRUCTURE OF AMINOPEPTIDASE PEPT (NP_980509.1) FROM BACILLUS CEREUS ATCC 10987 AT 2.04 A RESOLUTION | NP_980509.1, AMINOPEPTIDASE PEPT, PEPTIDASE FAMILY M20/M25/M40, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, AMINOPEPTIDASE, HYDROLASE, METAL-BINDING
1dlo:A (HIS361) to (PRO392) HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 | NUCLEOTIDYLTRANSFERASE
3t3w:E (GLY123) to (ALA141) CRYSTAL STRUCTURE OF PROBABLE ENOYL-COA HYDRATASE FROM MYCOBACTERIUM THERMORESISTIBILE | SSGCID, ENOYL-COA HYDRATASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, LYASE
4it7:A (GLY7) to (LYS43) CRYSTAL STRUCTURE OF AL-CPI | CPI, CYSTATIN, HYDROLASE INHIBITOR
4it7:B (GLY7) to (LYS43) CRYSTAL STRUCTURE OF AL-CPI | CPI, CYSTATIN, HYDROLASE INHIBITOR
4it7:C (GLY7) to (LYS43) CRYSTAL STRUCTURE OF AL-CPI | CPI, CYSTATIN, HYDROLASE INHIBITOR
4it7:D (GLY7) to (LYS43) CRYSTAL STRUCTURE OF AL-CPI | CPI, CYSTATIN, HYDROLASE INHIBITOR
3t4e:B (GLU43) to (SER67) 1.95 ANGSTROM CRYSTAL STRUCTURE OF SHIKIMATE 5-DEHYDROGENASE (AROE) FROM SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM IN COMPLEX WITH NAD | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, NAD(P)-BINDING ROSSMANN-FOLD C-TERMINAL DOMAIN, AMINOACID DEHYDROGENASE-LIKE N-TERMINAL DOMAIN, NAD, OXIDOREDUCTASE
3gf4:A (TYR313) to (GLY342) STRUCTURE OF UDP-GALACTOPYRANOSE MUTASE BOUND TO UDP-GLUCOSE | FLAVOENZYME, PROTEIN-LIGAND COMPLEX, CARBOHYDRATE BIOSYNTHESIS, FAD, FLAVOPROTEIN, ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
1dpz:B (GLU155) to (VAL183) STUCTURE OF MODIFIED 3-ISOPROPYLMALATE DEHYDROGENASE AT THE C- TERMINUS, HD711 | DEHYDROGENASE, MINOR GROOVE, PAPERCLIP MOTION, OXIDOREDUCTASE
4iug:A (ASN854) to (ASP897) CRYSTAL STRUCTURE OF BETA-GALACTOSIDASE FROM ASPERGILLUS ORYZAE IN COMPLEX WITH GALACTOSE | TIM BARREL, GLYCOSIDE HYDROLASE, HYDROLASE
2d1p:C (ASP73) to (TRP95) CRYSTAL STRUCTURE OF HETEROHEXAMERIC TUSBCD PROTEINS, WHICH ARE CRUCIAL FOR THE TRNA MODIFICATION | TRNA MODIFICATION, SULFUR TRANSFER, STRUCTURAL GENOMICS, TRANSLATION
2d1p:F (ASP73) to (TRP95) CRYSTAL STRUCTURE OF HETEROHEXAMERIC TUSBCD PROTEINS, WHICH ARE CRUCIAL FOR THE TRNA MODIFICATION | TRNA MODIFICATION, SULFUR TRANSFER, STRUCTURAL GENOMICS, TRANSLATION
2d1p:I (ASP73) to (TRP95) CRYSTAL STRUCTURE OF HETEROHEXAMERIC TUSBCD PROTEINS, WHICH ARE CRUCIAL FOR THE TRNA MODIFICATION | TRNA MODIFICATION, SULFUR TRANSFER, STRUCTURAL GENOMICS, TRANSLATION
2r5i:A (SER227) to (ARG251) PENTAMER STRUCTURE OF MAJOR CAPSID PROTEIN L1 OF HUMAN PAPILLOMA VIRUS TYPE 18 | HPV18, PENTAMER, STRUCTURE, TYPE SPECIFIC EPITOPE, CAPSID, CAPSID PROTEIN, VIRION, VIRAL PROTEIN
2die:A (ALA204) to (ALA237) ALKALINE ALPHA-AMYLASE AMYK FROM BACILLUS SP. KSM-1378 | BETA-ALPHA-BARRELS, HYDROLASE
2djx:B (GLY218) to (GLY249) CRYSTAL STRUCTURE OF NATIVE TRYPANOSOMA CRUZI DIHYDROOROTATE DEHYDROGENASE | CHAGAS' DISEASE, PYRIMIDINE BIOSYNTHESIS, FUMARATE REDUCTASE, ENERGY METABOLISM, REDOX HOMEOSTASIS, FLAVOPROTEIN, OXIDOREDUCTASE
3gtq:B (LYS404) to (LYS451) BACKTRACKED RNA POLYMERASE II COMPLEX INDUCED BY DAMAGE | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, ZINC- FINGER, DNA DAMAGE, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
2r9l:B (GLY86) to (PRO113) POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D IN COMPLEX WITH DNA | TRANSFERASE, PROTEIN-DNA COMPLEX, ATP-BINDING, LIGASE, NUCLEOTIDE- BINDING, TRANSFERASE-DNA COMPLEX
3gx9:A (LEU147) to (ALA187) STRUCTURE OF MORPHINONE REDUCTASE N189A MUTANT IN COMPLEX WITH TETRAHYDRONAD | H-TUNNELLING, FLAVOPROTEIN, NADH, MORPHINONE REDUCTASE, HYDRIDE TRANSFER, OXIDOREDUCTASE
3gxf:B (SER351) to (TRP381) CRYSTAL STRUCTURE OF ACID-BETA-GLUCOSIDASE WITH ISOFAGOMINE AT NEUTRAL PH | HYDROLASE, ALTERNATIVE INITIATION, DISEASE MUTATION, DISULFIDE BOND, GAUCHER DISEASE, GLYCOPROTEIN, GLYCOSIDASE, ICHTHYOSIS, LIPID METABOLISM, LYSOSOME, MEMBRANE, SPHINGOLIPID METABOLISM
3gxf:D (SER351) to (TRP381) CRYSTAL STRUCTURE OF ACID-BETA-GLUCOSIDASE WITH ISOFAGOMINE AT NEUTRAL PH | HYDROLASE, ALTERNATIVE INITIATION, DISEASE MUTATION, DISULFIDE BOND, GAUCHER DISEASE, GLYCOPROTEIN, GLYCOSIDASE, ICHTHYOSIS, LIPID METABOLISM, LYSOSOME, MEMBRANE, SPHINGOLIPID METABOLISM
3gxi:B (SER351) to (TRP381) CRYSTAL STRUCTURE OF ACID-BETA-GLUCOSIDASE AT PH 5.5 | HYDROLASE, ALTERNATIVE INITIATION, DISEASE MUTATION, DISULFIDE BOND, GAUCHER DISEASE, GLYCOPROTEIN, GLYCOSIDASE, ICHTHYOSIS, LIPID METABOLISM, LYSOSOME, MEMBRANE, SPHINGOLIPID METABOLISM
3gxi:C (SER351) to (ASP380) CRYSTAL STRUCTURE OF ACID-BETA-GLUCOSIDASE AT PH 5.5 | HYDROLASE, ALTERNATIVE INITIATION, DISEASE MUTATION, DISULFIDE BOND, GAUCHER DISEASE, GLYCOPROTEIN, GLYCOSIDASE, ICHTHYOSIS, LIPID METABOLISM, LYSOSOME, MEMBRANE, SPHINGOLIPID METABOLISM
3gxi:D (SER351) to (TRP381) CRYSTAL STRUCTURE OF ACID-BETA-GLUCOSIDASE AT PH 5.5 | HYDROLASE, ALTERNATIVE INITIATION, DISEASE MUTATION, DISULFIDE BOND, GAUCHER DISEASE, GLYCOPROTEIN, GLYCOSIDASE, ICHTHYOSIS, LIPID METABOLISM, LYSOSOME, MEMBRANE, SPHINGOLIPID METABOLISM
3ton:A (TYR1379) to (MET1421) CRYSTRAL STRUCTURE OF THE C-TERMINAL SUBUNIT OF HUMAN MALTASE- GLUCOAMYLASE | HYDROLASE, CARBOHYDRATE/SUGAR BINDING, MEMBRANE
3ton:B (TYR1379) to (MET1421) CRYSTRAL STRUCTURE OF THE C-TERMINAL SUBUNIT OF HUMAN MALTASE- GLUCOAMYLASE | HYDROLASE, CARBOHYDRATE/SUGAR BINDING, MEMBRANE
3top:A (TYR1379) to (ASP1420) CRYSTRAL STRUCTURE OF THE C-TERMINAL SUBUNIT OF HUMAN MALTASE- GLUCOAMYLASE IN COMPLEX WITH ACARBOSE | MEMBRANE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3top:B (TYR1379) to (ASP1420) CRYSTRAL STRUCTURE OF THE C-TERMINAL SUBUNIT OF HUMAN MALTASE- GLUCOAMYLASE IN COMPLEX WITH ACARBOSE | MEMBRANE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2rdg:A (GLU126) to (MET161) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN 11 IN COMPLEX WITH SIALYL LEWIS X | OB FOLD, BETA GRASP, PROTEIN-CARBOHYDRATE COMPLEX, TOXIN
2rdh:A (GLU126) to (MET161) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN 11 | OB FOLD, BETA GRASP, TOXIN
2rdh:C (GLU126) to (MET161) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN 11 | OB FOLD, BETA GRASP, TOXIN
1qe1:A (ALA360) to (PRO392) CRYSTAL STRUCTURE OF 3TC-RESISTANT M184I MUTANT OF HIV-1 REVERSE TRANSCRIPTASE | HIV, REVERSE TRANSCRIPTASE, 3TC, RESISTANCE, MUTANT, DNA POLYMERASE, TRANSFERASE
4jjt:C (GLY96) to (ALA114) THE CRYSTAL STRUCTURE OF ENOYL-COA HYDRATASE FROM MYCOBACTERIUM TUBERCULOSIS H37RV | STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, STRUCTURES OF MTB PROTEINS CONFERRING SUSCEPTIBILITY TO KNOWN MTB INHIBITORS, MTBI, LYASE
1ep4:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH S- 1153 | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NON-NUCLEOSIDE INHIBITOR, S-1153, DRUG DESIGN, TRANSFERASE
2rk8:A (MET173) to (ILE190) THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH PHOSPHONOFORMATE | KINASE, GLUCONEOGENESIS, LYASE, DECARBOXYLASE, GTP-BINDING, NUCLEOTIDE-BINDING
2rka:C (MET173) to (ILE190) THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH PHOSPHOGLYCOLATE | KINASE, GLUCONEOGENESIS, LYASE, DECARBOXYLASE, GTP-BINDING, NUCLEOTIDE-BINDING
2rke:A (MET173) to (ILE190) THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH SULFOACETATE. | KINASE, GLUCONEOGENESIS, LYASE, DECARBOXYLASE, GTP-BINDING, NUCLEOTIDE-BINDING
4jpj:A (CYS105) to (PHE134) CRYSTAL STRUCTURE OF THE GERMLINE-TARGETING HIV-1 GP120 ENGINEERED OUTER DOMAIN, EOD-GT6 | HIV-1 GP120, CD4 BINDING SITE, VRC01-LIKE BROADLY NEUTRALIZING ANTIBODIES, VIRAL PROTEIN
4jpj:C (CYS105) to (LYS135) CRYSTAL STRUCTURE OF THE GERMLINE-TARGETING HIV-1 GP120 ENGINEERED OUTER DOMAIN, EOD-GT6 | HIV-1 GP120, CD4 BINDING SITE, VRC01-LIKE BROADLY NEUTRALIZING ANTIBODIES, VIRAL PROTEIN
1qqr:A (ASP192) to (GLU218) CRYSTAL STRUCTURE OF STREPTOKINASE DOMAIN B | NON-PROTEOLYTIC, PLASMINOGEN ACTIVATION, FIBRINOLYSIS, HYDROLASE ACTIVATOR
1qqr:B (ASP192) to (ILE216) CRYSTAL STRUCTURE OF STREPTOKINASE DOMAIN B | NON-PROTEOLYTIC, PLASMINOGEN ACTIVATION, FIBRINOLYSIS, HYDROLASE ACTIVATOR
1qqr:C (ASP192) to (GLU218) CRYSTAL STRUCTURE OF STREPTOKINASE DOMAIN B | NON-PROTEOLYTIC, PLASMINOGEN ACTIVATION, FIBRINOLYSIS, HYDROLASE ACTIVATOR
4jsb:A (GLY131) to (LEU149) CRYSTAL STRUCTURE OF TFU_1878, A PUTATIVE ENOYL-COA HYDRATASE FROM THERMOBIFIDA FUSCA YX | STRUCTURAL GENOMICS, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, ENOYL-COA HYDRATASE/ISOMERASE FAMILY, PUTATIVE ENOYL-COA HYDRATASE/ISOMERASE, LYASE
1qui:A (LYS215) to (ASN243) PHOSPHATE-BINDING PROTEIN MUTANT WITH ASP 137 REPLACED BY GLY COMPLEX WITH BROMINE AND PHOSPHATE | BINDING PROTEIN, PHOSPHATE TRANSPORT
1f61:B (LYS197) to (THR229) CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM MYCOBACTERIUM TUBERCULOSIS | ALPHA-BETA BARREL, SWAPPED HELICES, APO-ENZYME, OPEN CONFORMATION, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, LYASE
3hgr:A (VAL81) to (ILE111) CRYSTAL STRUCTURE OF TOMATO OPR1 IN COMPLEX WITH PHB | ALPHA BETA BARREL, REDUCTASE, COMPLEX, FLAVOPROTEIN, ENANTIOSELECTIVITY, CYTOPLASM, FATTY ACID BIOSYNTHESIS, FMN, LIPID SYNTHESIS, NADP, OXIDOREDUCTASE, OXYLIPIN BIOSYNTHESIS
4k17:B (SER316) to (LEU344) CRYSTAL STRUCTURE OF MOUSE CARMIL RESIDUES 1-668 | PH DOMAIN, LRR DOMAIN, LIPID BINDING, PROTEIN-PROTEIN INTERACTION, PHOSPHATIDYLSERINE, PHOSPHATIDYLINOSITOL, PHOSPHATIDYLINOSITOL-5- PHOSPHATE, PLASMA MEMBRANE, LIPID BINDING PROTEIN
3hhm:A (ASN853) to (SER874) CRYSTAL STRUCTURE OF P110ALPHA H1047R MUTANT IN COMPLEX WITH NISH2 OF P85ALPHA AND THE DRUG WORTMANNIN | P110, P85, PI3KCA, PI3K, PIK3R1, PHOSPHATIDILYNOSITOL 3,4,5- TRIPHOSPHATE, WORTMANNIN, H1047R, ATP-BINDING, DISEASE MUTATION, KINASE, NUCLEOTIDE-BINDING, ONCOGENE, POLYMORPHISM, TRANSFERASE, TRANSFERASE/ONCOPROTEIN COMPLEX
1r6z:P (ILE600) to (ASN619) THE CRYSTAL STRUCTURE OF THE ARGONAUTE2 PAZ DOMAIN (AS A MBP FUSION) | DEVIANT OB FOLD, RNAI, GENE REGULATION
2v3d:A (SER351) to (TRP381) ACID-BETA-GLUCOSIDASE WITH N-BUTYL-DEOXYNOJIRIMYCIN | ACID-BETA-GLUCOSIDASE, N-BUTYL-DEOXYNOJIRIMYCINALTERNATIVE INITIATION, SPHINGOLIPID METABOLISM, GAUCHER DISEASE, DISEASE MUTATION, LIPID METABOLISM, POLYMORPHISM, GLYCOPROTEIN, PHARMACEUTICAL, N-BUTYL-DEOXYNOJIRIMYCIN, ALTERNATIVE SPLICING, MEMBRANE, LYSOSOME, HYDROLASE, GLYCOSIDASE
2v3d:B (SER351) to (TRP381) ACID-BETA-GLUCOSIDASE WITH N-BUTYL-DEOXYNOJIRIMYCIN | ACID-BETA-GLUCOSIDASE, N-BUTYL-DEOXYNOJIRIMYCINALTERNATIVE INITIATION, SPHINGOLIPID METABOLISM, GAUCHER DISEASE, DISEASE MUTATION, LIPID METABOLISM, POLYMORPHISM, GLYCOPROTEIN, PHARMACEUTICAL, N-BUTYL-DEOXYNOJIRIMYCIN, ALTERNATIVE SPLICING, MEMBRANE, LYSOSOME, HYDROLASE, GLYCOSIDASE
2v3e:A (SER351) to (TRP381) ACID-BETA-GLUCOSIDASE WITH N-NONYL-DEOXYNOJIRIMYCIN | ACID-BETA-GLUCOSIDASE, N-NONYL-DEOXYNOJIRIMYCINALTERNATIVE INITIATION, SPHINGOLIPID METABOLISM, N-NONYL-DEOXYNOJIRIMYCIN, GAUCHER DISEASE, DISEASE MUTATION, LIPID METABOLISM, POLYMORPHISM, GLYCOPROTEIN, PHARMACEUTICAL, ALTERNATIVE SPLICING, MEMBRANE, LYSOSOME, HYDROLASE, GLYCOSIDASE
2v3e:B (SER351) to (TRP381) ACID-BETA-GLUCOSIDASE WITH N-NONYL-DEOXYNOJIRIMYCIN | ACID-BETA-GLUCOSIDASE, N-NONYL-DEOXYNOJIRIMYCINALTERNATIVE INITIATION, SPHINGOLIPID METABOLISM, N-NONYL-DEOXYNOJIRIMYCIN, GAUCHER DISEASE, DISEASE MUTATION, LIPID METABOLISM, POLYMORPHISM, GLYCOPROTEIN, PHARMACEUTICAL, ALTERNATIVE SPLICING, MEMBRANE, LYSOSOME, HYDROLASE, GLYCOSIDASE
2v3f:A (SER351) to (TRP381) ACID-BETA-GLUCOSIDASE PRODUCED IN CARROT | ALTERNATIVE INITIATION, SPHINGOLIPID METABOLISM, GAUCHER DISEASE, DISEASE MUTATION, LIPID METABOLISM, POLYMORPHISM, GLYCOPROTEIN, PHARMACEUTICAL, N-BUTYL-DEOXYNOJIRIMYCIN, ALTERNATIVE SPLICING, ACID-BETA-GLUCOSIDASE, MEMBRANE, LYSOSOME, HYDROLASE, GLYCOSIDASE
2v3f:B (SER351) to (TRP381) ACID-BETA-GLUCOSIDASE PRODUCED IN CARROT | ALTERNATIVE INITIATION, SPHINGOLIPID METABOLISM, GAUCHER DISEASE, DISEASE MUTATION, LIPID METABOLISM, POLYMORPHISM, GLYCOPROTEIN, PHARMACEUTICAL, N-BUTYL-DEOXYNOJIRIMYCIN, ALTERNATIVE SPLICING, ACID-BETA-GLUCOSIDASE, MEMBRANE, LYSOSOME, HYDROLASE, GLYCOSIDASE
3hid:A (SER305) to (LYS332) CRYSTAL STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM YERSINIA PESTIS CO92 | NIAID STRUCTURAL GENOMICS, ADENYLOSUCCINATE SYNTHETASE, VIRULENCE ASSOCIATED FACTOR, PURA, PURINE RIBONUCLEOTIDE BIOSYNTHESIS, CYTOPLASM, GTP-BINDING, LIGASE, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, PURINE BIOSYNTHESIS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
1fko:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF NNRTI RESISTANT K103N MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DMP-266(EFAVIRENZ) | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NON-NUCLEOSIDE INHIBITOR, DMP-266, EFAVIRENZ, DRUG RESISTANCE MUTATION, DRUG DESIGN, TRANSFERASE
3ue9:A (ARG323) to (LYS349) CRYSTAL STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE (AMPSASE) (PURA) FROM BURKHOLDERIA THAILANDENSIS | SSGCID, LIGASE, ADSS, BTH_I2245, IMP-ASPARTATE LIGASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3ue9:B (ARG323) to (LYS349) CRYSTAL STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE (AMPSASE) (PURA) FROM BURKHOLDERIA THAILANDENSIS | SSGCID, LIGASE, ADSS, BTH_I2245, IMP-ASPARTATE LIGASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3ue9:C (ARG323) to (LYS349) CRYSTAL STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE (AMPSASE) (PURA) FROM BURKHOLDERIA THAILANDENSIS | SSGCID, LIGASE, ADSS, BTH_I2245, IMP-ASPARTATE LIGASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
2v8v:B (LEU359) to (GLN390) CRYSTAL STRUCTURE OF MUTANT R322A OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI | HYDROLASE, DI-ZINC CENTER, AMIDOHYDROLASE, ALPHA AND BETA PROTEIN
2v8v:D (LEU359) to (GLN390) CRYSTAL STRUCTURE OF MUTANT R322A OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI | HYDROLASE, DI-ZINC CENTER, AMIDOHYDROLASE, ALPHA AND BETA PROTEIN
3uka:A (GLY418) to (GLY446) CRYSTAL STRUCTURE OF UDP-GALACTOPYRANOSE MUTASE FROM ASPERGILLUS FUMIGATUS | UDP-GALACTOPYRANOSE MUTASE, AFUGM, FLAVOENZYME, FAD, ISOMERASE
3uka:B (GLY418) to (GLY446) CRYSTAL STRUCTURE OF UDP-GALACTOPYRANOSE MUTASE FROM ASPERGILLUS FUMIGATUS | UDP-GALACTOPYRANOSE MUTASE, AFUGM, FLAVOENZYME, FAD, ISOMERASE
3uka:D (GLY418) to (GLY446) CRYSTAL STRUCTURE OF UDP-GALACTOPYRANOSE MUTASE FROM ASPERGILLUS FUMIGATUS | UDP-GALACTOPYRANOSE MUTASE, AFUGM, FLAVOENZYME, FAD, ISOMERASE
3ukh:A (GLY418) to (GLY446) CRYSTAL STRUCTURE OF UDP-GALACTOPYRANOSE MUTASE FROM ASPERGILLUS FUMIGATUS IN COMPLEX WITH UDPGALP (NON-REDUCED) | FLAVOENZYME, FAD, FADH2 ISOMERASE, ISOMERASE
4yw8:A (MET173) to (ILE190) STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH 3-MERCAPTOPICOLINIC ACID | KINASE, GLUCONEOGENESIS, LYASE, TRANSFERASE
3ukq:A (GLY418) to (GLY446) CRYSTAL STRUCTURE OF R327K UDP-GALACTOPYRANOSE MUTASE FROM ASPERGILLUS FUMIGATUS IN COMPLEX WITH UDPGALP | FLAVOENZYME, FAD, ISOMERASE
3ukq:C (GLY418) to (GLY446) CRYSTAL STRUCTURE OF R327K UDP-GALACTOPYRANOSE MUTASE FROM ASPERGILLUS FUMIGATUS IN COMPLEX WITH UDPGALP | FLAVOENZYME, FAD, ISOMERASE
1rn7:A (GLY13) to (PRO48) STRUCTURE OF HUMAN CYSTATIN D | INHIBITOR OF CYSTEINE PEPTIDASES, CYSTATIN D, PROTEIN BINDING
1rt4:A (ALA360) to (LYS390) HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH UC781 | NUCLEOTIDYLTRANSFERASE, HIV-1 REVERSE TRANSCRIPTASE, AIDS, NONNUCLEOSIDE INHIBITION, DRUG DESIGN
1rt6:A (HIS361) to (PRO392) HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH UC38 | NUCLEOTIDYLTRANSFERASE, HIV-1 REVERSE TRANSCRIPTASE, AIDS, NONNUCLEOSIDE INHIBITION, DRUG DESIGN
1rti:A (ALA360) to (LYS390) HIGH RESOLUTION STRUCTURES OF HIV-1 RT FROM FOUR RT- INHIBITOR COMPLEXES | HIV-1 REVERSE TRANSCRIPTASE, NUCLEOTIDYLTRANSFERASE
1rti:B (LYS22) to (GLY51) HIGH RESOLUTION STRUCTURES OF HIV-1 RT FROM FOUR RT- INHIBITOR COMPLEXES | HIV-1 REVERSE TRANSCRIPTASE, NUCLEOTIDYLTRANSFERASE
1g24:A (GLY171) to (LYS196) THE CRYSTAL STRUCTURE OF EXOENZYME C3 FROM CLOSTRIDIUM BOTULINUM | C3, ADP-RIBOSYLTRANSFERASE
2fbt:A (GLY51) to (GLY80) WRN EXONUCLEASE | RECQ, WRN, WERNER SYNDROME, 3'-5' EXONUCLEASE, DNAQ FAMILY, TRANSFERASE
2fbv:A (GLY51) to (GLY80) WRN EXONUCLEASE, MN COMPLEX | RECQ, WRN, WERNER SYNDROME, 3'-5' EXONUCLEASE, DNAQ FAMILY, TRANSFERASE
2fbx:A (GLY51) to (GLY80) WRN EXONUCLEASE, MG COMPLEX | RECQ, WRN, WERNER SYNDROME, 3'-5' EXONUCLEASE, DNAQ FAMILY, TRANSFERASE
2fby:A (GLY51) to (GLY80) WRN EXONUCLEASE, EU COMPLEX | RECQ, WRN, WERNER SYNDROME, 3'-5' EXONUCLEASE, DNAQ FAMILY, TRANSFERASE
2vg5:A (ALA360) to (LYS390) CRYSTAL STRUCTURES OF HIV-1 REVERSE TRANSCRIPTASE COMPLEXES WITH THIOCARBAMATE NON-NUCLEOSIDE INHIBITORS | DNA-DIRECTED DNA POLYMERASE, THIOCARBAMATES, PHOSPHORYLATION, DNA INTEGRATION, MAGNESIUM, ZINC-FINGER, RNA-BINDING, TRANSFERASE, LIPOPROTEIN, CORE PROTEIN, ENDONUCLEASE, METAL-BINDING, ZINC, AIDS, HIV-1, VIRION, NUCLEUS, MEMBRANE, ASPARTYL PROTEASE, CAPSID MATURATION, MULTIFUNCTIONAL ENZYME, RNA-DIRECTED DNA POLYMERASE, REVERSE TRANSCRIPTASE, NUCLEOTIDYLTRANSFERASE, DNA RECOMBINATION, VIRAL NUCLEOPROTEIN, PROTEASE, NUCLEASE, MYRISTATE, HYDROLASE, CYTOPLASM, NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
3ury:A (GLU238) to (SER265) CRYSTAL STRUCTURE OF SUPERANTIGEN-LIKE PROTEIN, EXOTOXIN FROM STAPHYLOCOCCUS AUREUS SUBSP. AUREUS NCTC 8325 | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, SUPERANTIGEN-LIKE PROTEIN, TOXIN
4kko:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH 4- ((4-METHOXY-6-(2-MORPHOLINOETHOXY)-1,3,5-TRIAZIN-2-YL)AMINO)-2-((3- METHYLBUT-2-EN-1-YL)OXY)BENZONITRILE (JLJ513), A NON-NUCLEOSIDE INHIBITOR | POLYMERASE, TRANSFERASE, HYDROLASE/INHIBITOR, RNASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4klt:A (LYS148) to (VAL177) DNA POLYMERASE BETA MISMATCHED PRODUCT COMPLEX WITH MN2+, 30 MIN | DNA POLYMERASE, TRANSFERASE, LYASE-DNA COMPLEX
2fpc:B (LEU170) to (THR186) STRUCTURE OF STRICTOSIDINE SYNTHASE, THE BIOSYNTHETIC ENTRY TO THE MONOTERPENOID INDOLE ALKALOID FAMILY | SIX BLADED BETA PROPELLER FOLD, STR1, SYNTHASE, LYASE
3v05:C (GLU157) to (GLU194) 2.4 ANGSTROM CRYSTAL STRUCTURE OF SUPERANTIGEN-LIKE PROTEIN FROM STAPHYLOCOCCUS AUREUS. | CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, SUPERANTIGEN-LIKE PROTEIN, TOXIN
3v05:D (GLU157) to (GLU194) 2.4 ANGSTROM CRYSTAL STRUCTURE OF SUPERANTIGEN-LIKE PROTEIN FROM STAPHYLOCOCCUS AUREUS. | CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, SUPERANTIGEN-LIKE PROTEIN, TOXIN
1s6p:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R100943 | REVERSE TRANSCRIPTASE, NNRTI, NONNUCLEOSIDE INHIBITOR, PROTEIN- INHIBITOR COMPLEX, AIDS, DRUG DESIGN, DRUG RESISTANCE, TRANSFERASE
2fsk:A (ASN65) to (PRO109) CRYSTAL STRUCTURE OF TA0583, AN ARCHAEAL ACTIN HOMOLOG, SEMET DATA | ACTIN HOMOLOG, ARCHAEA, ATPASE, MREB, PARM, STRUCTURAL PROTEIN
3v15:B (ASP47) to (ASP84) CRYSTAL STRUCTURE OF THE FE(II)/ALPHA-KETOGLUTARATE DEPENDENT TAURINE DIOXYGENASE FROM PSEUDOMONAS PUTIDA KT2440 | JELLY ROLL MOTIF, DIOXYGENASE, ALPHA-KETOGLUTARATE, FE(II), OXIDOREDUCTASE
1s9e:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R129385 | REVERSE TRANSCRIPTASE, RT, NNRTI, NONNUCLEOSIDE INHIBITOR, PROTEIN-INHIBITOR COMPLEX, HIV, AIDS, DRUG DESIGN, R129385, TRANSFERASE
3v17:A (GLY18) to (ARG46) CRYSTAL STRUCTURE OF THE FE(II)/ALPHA-KETOGLUTARATE DEPENDENT TAURINE DIOXYGENASE FROM PSEUDOMONAS PUTIDA KT2440 | JELLY ROLL MOTIF, DIOXYGENASE, FE(II), ALPHA-KETOGLUTARATE, TAURINE, OXIDOREDUCTASE
3v17:A (ASP47) to (ASP84) CRYSTAL STRUCTURE OF THE FE(II)/ALPHA-KETOGLUTARATE DEPENDENT TAURINE DIOXYGENASE FROM PSEUDOMONAS PUTIDA KT2440 | JELLY ROLL MOTIF, DIOXYGENASE, FE(II), ALPHA-KETOGLUTARATE, TAURINE, OXIDOREDUCTASE
3v17:B (GLY18) to (ARG46) CRYSTAL STRUCTURE OF THE FE(II)/ALPHA-KETOGLUTARATE DEPENDENT TAURINE DIOXYGENASE FROM PSEUDOMONAS PUTIDA KT2440 | JELLY ROLL MOTIF, DIOXYGENASE, FE(II), ALPHA-KETOGLUTARATE, TAURINE, OXIDOREDUCTASE
3v17:B (ASP47) to (ASP84) CRYSTAL STRUCTURE OF THE FE(II)/ALPHA-KETOGLUTARATE DEPENDENT TAURINE DIOXYGENASE FROM PSEUDOMONAS PUTIDA KT2440 | JELLY ROLL MOTIF, DIOXYGENASE, FE(II), ALPHA-KETOGLUTARATE, TAURINE, OXIDOREDUCTASE
2fud:A (ASN64) to (ASP87) HUMAN CATHEPSIN S WITH INHIBITOR CRA-27566 | CYSTEINE PROTEASE, PROTEINASE, PAPAIN, 27566, HYDROLASE
4ko0:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH AN ANILINYLPYRIMIDINE DERIVATIVE (JLJ-135) | P51/P66, HETERO DIMER, NNRTI, NONNUCLEOSIDE INHIBITOR, AIDS, HIV,, DNA RECOMBINATION, RNA-DIRECTED DNA POLYMERASE, DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MULTIFUNCTIONAL ENZYME, TRANSFERASE, HYDROLASE-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3v44:A (ALA60) to (VAL78) CRYSTAL STRUCTURE OF THE N-TERMINAL FRAGMENT OF ZEBRAFISH TLR5 | FLAGELLIN, INNATE IMMUNITY, LEUCINE-RICH REPEAT, INNATE IMMUNE RECEPTOR, IMMUNE SYSTEM
3v4i:C (HIS361) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) WITH DNA AND AZTTP | HIV-1 REVERSE TRANSCRIPTASE, ZIDOVUDINE, RT-DNA COMPLEX, TRANSFERASE- DNA COMPLEX, DRUG RESISTANCE MUTATION, AIDS, DNA RECOMBINATION, DNA- DIRECTED DNA POLYMERASE, RNASE H, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDYLTRANSFERASE, RNA-DIRECTED DNA POLYMERASE TRANSFERASE, TRANSFERASE-DNA COMPLEX COMPLEX
3v7j:A (LYS148) to (VAL177) CO-CRYSTAL STRUCTURE OF WILD TYPE RAT POLYMERASE BETA: ENZYME-DNA BINARY COMPLEX | PROTEIN-DNA COMPLEX, REPAIR POLYMERASE, TRANSFERASE-DNA COMPLEX
3v7k:A (LYS148) to (VAL177) CO-CRYSTAL STRUCTURE OF K72E VARIANT OF RAT POLYMERASE BETA: ENZYME- DNA BINARY COMPLEX | PROTEIN-DNA COMPLEX, REPAIR POLYMERASE, TRANSFERASE-DNA COMPLEX
3v81:C (HIS361) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) WITH DNA AND THE NONNUCLEOSIDE INHIBITOR NEVIRAPINE | P51/P66, HETERO DIMER, NNRTI, NONNUCLEOSIDE INHIBITOR, AIDS, DNA, RECOMBINATION, RNA-DIRECTED DNA POLYMERASE, VIRAMUNE, DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MULTIFUNCTIONAL ENZYME, TRANSFERASE, TRANSFERASE-DNA COMPLEX, AZT, ZIDOVUDINE
3i0s:A (ALA360) to (PRO392) CRYSTAL STRUCTURE OF HIV REVERSE TRANSCRIPTASE IN COMPLEX WITH INHIBITOR 7 | HIV-1 REVERSE TRANSCRIPTASE, NON-NUCLEOSIDE INHIBITION, NUCLEOTIDYLTRASFERASE, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HOST-VIRUS INTERACTION, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RIBOSOMAL FRAMESHIFTING, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER
3i4e:B (LYS198) to (THR230) CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BURKHOLDERIA PSEUDOMALLEI | ISOCITRATE LYASE, STRUCTURAL GENOMICS, LYASE, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID
3i4e:C (LYS198) to (THR230) CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BURKHOLDERIA PSEUDOMALLEI | ISOCITRATE LYASE, STRUCTURAL GENOMICS, LYASE, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID
2vsu:A (GLY115) to (CYS133) A TERNARY COMPLEX OF HYDROXYCINNAMOYL-COA HYDRATASE-LYASE ( HCHL) WITH ACETYL-COENZYME A AND VANILLIN GIVES INSIGHTS INTO SUBSTRATE SPECIFICITY AND MECHANISM. | LYASE, ALDOLASE, CROTONASE, HYDRATASE
2vt0:A (SER351) to (TRP381) X-RAY STRUCTURE OF A CONJUGATE WITH CONDURITOL-BETA-EPOXIDE OF ACID-BETA-GLUCOSIDASE OVEREXPRESSED IN CULTURED PLANT CELLS | HYDROLASE, ALTERNATIVE INITIATION, SPHINGOLIPID METABOLISM, ISRAEL STRUCTURAL PROTEOMICS CENTER, DISEASE MUTATION, GLUCOCEREBROSIDASE, PHARMACEUTICAL, GAUCHER DISEASE, LIPID METABOLISM, GLUCOSIDASE, GLYCOSIDASE, POLYMORPHISM, GLYCOPROTEIN, ISPC, MEMBRANE, CEREZYME, LYSOSOME, STRUCTURAL GENOMICS, ALTERNATIVE SPLICING
2vt0:B (SER351) to (TRP381) X-RAY STRUCTURE OF A CONJUGATE WITH CONDURITOL-BETA-EPOXIDE OF ACID-BETA-GLUCOSIDASE OVEREXPRESSED IN CULTURED PLANT CELLS | HYDROLASE, ALTERNATIVE INITIATION, SPHINGOLIPID METABOLISM, ISRAEL STRUCTURAL PROTEOMICS CENTER, DISEASE MUTATION, GLUCOCEREBROSIDASE, PHARMACEUTICAL, GAUCHER DISEASE, LIPID METABOLISM, GLUCOSIDASE, GLYCOSIDASE, POLYMORPHISM, GLYCOPROTEIN, ISPC, MEMBRANE, CEREZYME, LYSOSOME, STRUCTURAL GENOMICS, ALTERNATIVE SPLICING
1gt8:A (GLY302) to (GLY333) DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX WITH NADPH AND URACIL-4-ACETIC ACID | ELECTRON TRANSFER, FLAVIN, IRON-SULFUR CLUSTERS, PYRIMIDINE CATABOLISM, 5-FLUOROURACIL DEGRADATION, OXIDOREDUCTASE
1gt8:C (GLY302) to (GLY333) DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX WITH NADPH AND URACIL-4-ACETIC ACID | ELECTRON TRANSFER, FLAVIN, IRON-SULFUR CLUSTERS, PYRIMIDINE CATABOLISM, 5-FLUOROURACIL DEGRADATION, OXIDOREDUCTASE
1gt8:D (GLY302) to (GLY333) DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX WITH NADPH AND URACIL-4-ACETIC ACID | ELECTRON TRANSFER, FLAVIN, IRON-SULFUR CLUSTERS, PYRIMIDINE CATABOLISM, 5-FLUOROURACIL DEGRADATION, OXIDOREDUCTASE
1gth:A (GLY302) to (GLY333) DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX WITH NADPH AND 5-IODOURACIL | ELECTRON TRANSFER, FLAVIN, IRON-SULFUR CLUSTERS, PYRIMIDINE CATABOLISM, 5-FLUOROURACIL DEGRADATION, OXIDOREDUCTASE
1gth:D (GLY302) to (GLY333) DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX WITH NADPH AND 5-IODOURACIL | ELECTRON TRANSFER, FLAVIN, IRON-SULFUR CLUSTERS, PYRIMIDINE CATABOLISM, 5-FLUOROURACIL DEGRADATION, OXIDOREDUCTASE
3i6s:A (GLN469) to (PRO504) CRYSTAL STRUCTURE OF THE PLANT SUBTILISIN-LIKE PROTEASE SBT3 | SUBTILISIN-LIKE, PROTEASE, PA-DOMAIN, FN3-DOMAIN, HYDROLASE
3i6s:B (GLN469) to (PRO504) CRYSTAL STRUCTURE OF THE PLANT SUBTILISIN-LIKE PROTEASE SBT3 | SUBTILISIN-LIKE, PROTEASE, PA-DOMAIN, FN3-DOMAIN, HYDROLASE
1gvq:A (THR147) to (SER182) STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE AND COMPLEXED WITH CYCLOHEXANONE | FLAVOENZYME, EXPLOSIVE DEGRADATION, STEROID BINDING
1gvr:A (THR147) to (SER182) STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE AND COMPLEXED WITH 2,4,6 TRINITROTOLUENE | OXIDOREDUCTASE, FLAVOENZYME, EXPLOSIVE DEGRADATION, STEROID BINDING
1gvs:A (ALA71) to (ARG106) STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE AND COMPLEXED WITH PICRIC ACID | FLAVOENZYME, EXPLOSIVE DEGRADATION, STEROID BINDING, OXIDOREDUCTASE
1gvs:A (THR147) to (SER182) STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE AND COMPLEXED WITH PICRIC ACID | FLAVOENZYME, EXPLOSIVE DEGRADATION, STEROID BINDING, OXIDOREDUCTASE
1sv5:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF K103N MUTANT HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R165335 | AIDS, HIV, DRUG DESIGN, REVERSE TRANSCRIPTASE, RT, PROTEIN-INHIBITOR COMPLEX, DRUG RESISTANCE, TRANSFERASE
2gbx:A (ALA13) to (GLY42) CRYSTAL STRUCTURE OF BIPHENYL 2,3-DIOXYGENASE FROM SPHINGOMONAS YANOIKUYAE B1 BOUND TO BIPHENYL | RIESKE OXYGENASE, OXIDOREDUCTASE, NON HEME IRON, DIOXYGENASE
2vye:A (PRO294) to (ASP320) CRYSTAL STRUCTURE OF THE DNAC-SSDNA COMPLEX | HYDROLASE, DNA REPLICATION, NUCLEOTIDE-BINDING, DNAC, HELICASE, ATP-BINDING, HYDROLASE-DNA COMPLEX
4zjq:E (ARG239) to (LEU270) CRYSTAL STRUCTURE OF ACRB DELETION MUTANT IN COMPLEX WITH ANTIBIOTIC IN P21 SPACE GROUP | TRANSPORT PROTEIN
1h2t:C (PRO222) to (HIS248) STRUCTURE OF THE HUMAN NUCLEAR CAP-BINDING-COMPLEX (CBC) IN COMPLEX WITH A CAP ANALOGUE M7GPPPG | M7GCAP, CAP-BINDING-COMPLEX, RNP DOMAIN, MIF4G DOMAIN, RNA MATURATION, RNA EXPORT, NUCLEAR PROTEIN, RNA-BINDING
1h2u:A (PRO222) to (HIS248) STRUCTURE OF THE HUMAN NUCLEAR CAP-BINDING-COMPLEX (CBC) IN COMPLEX WITH A CAP ANALOGUE M7GPPPG | M7GCAP, CAP-BINDING-COMPLEX, RNP DOMAIN, MIF4G DOMAIN, RNA MATURATION, RNA EXPORT, NUCLEAR PROTEIN, RNA-BINDING
1h2u:B (PRO222) to (HIS248) STRUCTURE OF THE HUMAN NUCLEAR CAP-BINDING-COMPLEX (CBC) IN COMPLEX WITH A CAP ANALOGUE M7GPPPG | M7GCAP, CAP-BINDING-COMPLEX, RNP DOMAIN, MIF4G DOMAIN, RNA MATURATION, RNA EXPORT, NUCLEAR PROTEIN, RNA-BINDING
1h2v:C (PRO222) to (HIS248) STRUCTURE OF THE HUMAN NUCLEAR CAP-BINDING-COMPLEX (CBC) | CAP-BINDING-COMPLEX, RNP DOMAIN, MIF4G DOMAIN, RNA MATURATION, RNA EXPORT, NUCLEAR PROTEIN, RNA-BINDING
2gjp:A (TYR203) to (ALA237) STRUCTURE OF BACILLUS HALMAPALUS ALPHA-AMYLASE, CRYSTALLIZED WITH THE SUBSTRATE ANALOGUE ACARBOSE AND MALTOSE | ALPHA-AMYLASE, MALTOSE BINDING SITE, BACILLUS HALMAPALUS, HYDROLASE
2gjr:A (TYR203) to (ALA237) STRUCTURE OF BACILLUS HALMAPALUS ALPHA-AMYLASE WITHOUT ANY SUBSTRATE ANALOGUES | ALPHA-AMYLASE, BACILLUS HALMAPALUS, HYDROLASE
4zlj:A (ARG239) to (LEU270) CRYSTAL STRUCTURE OF TRANSPORTER ACRB | TRANSPORT PROTEIN
4zll:A (ARG239) to (LEU270) CRYSTAL STRUCTURE OF TRANSPORTER ACRB TRIPLE MUTANT | TRANSPORT PROTEIN
1h4y:A (GLY19) to (ASN48) STRUCTURE OF THE ANTI-SIGMA FACTOR ANTAGONIST SPOIIAA IN ITS UNPHOSPHORYLATED FORM | CELL DIFFERENTIATION, CRYSTALLOGRAPHY, PHOSPHORYLATION, SIGMA FACTORS, SPORULATION
1h51:A (THR147) to (SER182) OXIDISED PENTAERYTHRITOL TETRANITRATE REDUCTASE (SCN COMPLEX) | OXIDOREDUCTASE, FLAVOENZYME, EXPLOSIVE DEGRADATION, STEROID BINDING
1h62:A (THR147) to (SER182) STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE IN COMPLEX WITH 1,4-ANDROSTADIEN-3,17-DIONE | FLAVOENZYME, STEROID BINDING, OXIDOREDUCTASE
1h60:A (THR147) to (SER182) STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE IN COMPLEX WITH PROGESTERONE | STEROID BINDING, FLAVOENZYME, OXIDOREDUCTASE
1h61:A (ALA71) to (ARG106) STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE IN COMPLEX WITH PREDNISONE | STEROID BINDING, OXIDOREDUCTASE, FLAVOENZYME
1h6k:A (PRO222) to (HIS248) NUCLEAR CAP BINDING COMPLEX | M7G CAP, CAP-BINDING-COMPLEX, RNP DOMAIN, MIF4G DOMAIN, RNA MATURATION, RNA EXPORT, CRYSTAL STRUCTURE, NUCLEAR PROTEIN
1h6k:B (PRO222) to (HIS248) NUCLEAR CAP BINDING COMPLEX | M7G CAP, CAP-BINDING-COMPLEX, RNP DOMAIN, MIF4G DOMAIN, RNA MATURATION, RNA EXPORT, CRYSTAL STRUCTURE, NUCLEAR PROTEIN
1h6k:C (PRO222) to (HIS248) NUCLEAR CAP BINDING COMPLEX | M7G CAP, CAP-BINDING-COMPLEX, RNP DOMAIN, MIF4G DOMAIN, RNA MATURATION, RNA EXPORT, CRYSTAL STRUCTURE, NUCLEAR PROTEIN
2w3r:B (GLY484) to (ALA515) CRYSTAL STRUCTURE OF XANTHINE DEHYDROGENASE (DESULFO FORM) FROM RHODOBACTER CAPSULATUS IN COMPLEX WITH HYPOXANTHINE | XDH, GOUT, IRON, XANTHINE, IRON-SULFUR, MOLYBDENUM COFACTOR, HYPOXANTHINE, METAL-BINDING, OXIDOREDUCTASE
2w3r:D (GLY484) to (ALA515) CRYSTAL STRUCTURE OF XANTHINE DEHYDROGENASE (DESULFO FORM) FROM RHODOBACTER CAPSULATUS IN COMPLEX WITH HYPOXANTHINE | XDH, GOUT, IRON, XANTHINE, IRON-SULFUR, MOLYBDENUM COFACTOR, HYPOXANTHINE, METAL-BINDING, OXIDOREDUCTASE
4lbu:A (ARG132) to (ALA154) TRNA GUANINE TRANSGLYCOSYLASE (TGT) IN COMPLEX WITH FURANOSIDE-BASED LIN-BENZOGUANINE 2 | TIM BARREL, GLYCOSYLTRANSFERASE, ZINC-BINDING, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2w55:D (GLY484) to (ALA515) CRYSTAL STRUCTURE OF XANTHINE DEHYDROGENASE (E232Q VARIANT) FROM RHODOBACTER CAPSULATUS IN COMPLEX WITH HYPOXANTHINE | XDH, GOUT, IRON, XANTHINE, IRON-SULFUR, MOLYBDENUM COFACTOR, HYPOXANTHINE, METAL-BINDING, OXIDOREDUCTASE
2w55:H (GLY484) to (ALA515) CRYSTAL STRUCTURE OF XANTHINE DEHYDROGENASE (E232Q VARIANT) FROM RHODOBACTER CAPSULATUS IN COMPLEX WITH HYPOXANTHINE | XDH, GOUT, IRON, XANTHINE, IRON-SULFUR, MOLYBDENUM COFACTOR, HYPOXANTHINE, METAL-BINDING, OXIDOREDUCTASE
4ztl:C (ARG164) to (GLY193) IRAK4-INHIBITOR CO-STRUCTURE | KINASE, PHOSPHATASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ztm:B (PHE165) to (GLY193) IRAK4-INHIBITOR CO-STRUCTURE | KINASE, PHOSPHATASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3io1:B (MSE335) to (ASP366) CRYSTAL STRUCTURE OF AMINOBENZOYL-GLUTAMATE UTILIZATION PROTEIN FROM KLEBSIELLA PNEUMONIAE | AMINOBENZOYL-GLUTAMATE UTILIZATION PROTEIN, PEPTIDASE_M20D SUPERFAMILY, PROTEIN STRUCTURE INITIATIVE II, NYSGXRC, 11203B, STRUCTURAL GENOMICS, PSI-2, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, HYDROLASE
4lgx:A (TYR371) to (GLU396) STRUCTURE OF CHITINASE D FROM SERRATIA PROTEAMACULANS REVEALED AN UNUSUALLY CONSTRAINED SUBSTRATE BINDING SITE | TIM BARREL, HYDROLASE
2w7p:B (SER475) to (SER514) STRUCTURE AND ACTIVITY OF BYPASS SYNTHESIS BY HUMAN DNA POLYMERASE KAPPA OPPOSITE THE 7,8-DIHYDRO-8- OXODEOXYGUANOSINE ADDUCT | 8-OXO-2P-DEOXY-GUANOSINE-5P-MONOPHOSPHATE, TRANSLESION DNA POLYMERASE, HUMAN DNA POLYMERASE KAPPA, DATP, DNA REPAIR, DNA DAMAGE, DNA-BINDING PROTEIN
1thn:D (THR54) to (VAL80) CRYSTAL STRUCTURES OF THE ADP AND ATP BOUND FORMS OF THE BACILLUS ANTI-SIGMA FACTOR SPOIIAB IN COMPLEX WITH THE ANTI-ANTI-SIGMA SPOIIAA: INHIBITORY COMPLEX WITH ADP, CRYSTAL FORM I | SPOIIAB, SPOIIAA, ANTI-SIGMA, ANTI-ANTI-SIGMA, SPORULATION, SERINE KINASE, TRANSCRIPTION
2w9p:B (ILE5) to (PHE37) CRYSTAL STRUCTURE OF POTATO MULTICYSTATIN | PROTEASE INHIBITOR, THIOL PROTEASE INHIBITOR, HYDROLASE INHIBITOR
2w9p:C (GLY4) to (GLU39) CRYSTAL STRUCTURE OF POTATO MULTICYSTATIN | PROTEASE INHIBITOR, THIOL PROTEASE INHIBITOR, HYDROLASE INHIBITOR
2w9p:D (GLY4) to (GLU39) CRYSTAL STRUCTURE OF POTATO MULTICYSTATIN | PROTEASE INHIBITOR, THIOL PROTEASE INHIBITOR, HYDROLASE INHIBITOR
2w9p:E (ILE5) to (GLU39) CRYSTAL STRUCTURE OF POTATO MULTICYSTATIN | PROTEASE INHIBITOR, THIOL PROTEASE INHIBITOR, HYDROLASE INHIBITOR
2w9p:H (GLY4) to (GLU39) CRYSTAL STRUCTURE OF POTATO MULTICYSTATIN | PROTEASE INHIBITOR, THIOL PROTEASE INHIBITOR, HYDROLASE INHIBITOR
2w9p:I (VAL6) to (VAL38) CRYSTAL STRUCTURE OF POTATO MULTICYSTATIN | PROTEASE INHIBITOR, THIOL PROTEASE INHIBITOR, HYDROLASE INHIBITOR
2w9q:A (GLY4) to (GLU39) CRYSTAL STRUCTURE OF POTATO MULTICYSTATIN-P212121 | PROTEASE INHIBITOR, THIOL PROTEASE INHIBITOR, HYDROLASE INHIBITOR
1tkt:A (HIS361) to (PRO392) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW426318 | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NNRTI, GW426318, DRUG DESIGN, TRANSFERASE
1tkx:A (HIS361) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW490745 | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NNRTI, GW490745, DRUG DESIGN, TRANSFERASE
1tkz:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW429576 | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NNRTI, GW429576, DRUG DESIGN, TRANSFERASE
3is9:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF THE HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH THE ALKENYLDIARYLMETHANE (ADAM) NON-NUCLEOSIDE RT INHIBITOR DIMETHYL 3,3'-(6-METHOXY-6-OXOHEX-1-ENE-1,1- DIYL)BIS(5-CYANO-6-METHOXYBENZOATE). | NNRTI, NONNUCLEOSIDE INHIBITOR, AIDS, HIV, P51/P66, ADAM, ASPARTYL PROTEASE, CELL MEMBRANE, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER, TRANSFERASE-HYDROLASE COMPLEX
2h7j:B (ASN67) to (ASP87) CRYSTAL STRUCTURE OF CATHEPSIN S IN COMPLEX WITH A NONPEPTIDIC INHIBITOR. | CATHEPSIN S, NONPEPTIDIC, CHLOROMETHYLKETONE, SUBSTRATE ACTIVITY SCREENING, HYDROLASE
1hmv:B (LYS22) to (GLY51) THE STRUCTURE OF UNLIGANDED REVERSE TRANSCRIPTASE FROM THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 | NUCLEOTIDYLTRANSFERASE
1hmv:D (LYS22) to (GLY51) THE STRUCTURE OF UNLIGANDED REVERSE TRANSCRIPTASE FROM THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 | NUCLEOTIDYLTRANSFERASE
1hmv:F (LYS22) to (GLY51) THE STRUCTURE OF UNLIGANDED REVERSE TRANSCRIPTASE FROM THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 | NUCLEOTIDYLTRANSFERASE
1hmv:H (LYS22) to (GLY51) THE STRUCTURE OF UNLIGANDED REVERSE TRANSCRIPTASE FROM THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 | NUCLEOTIDYLTRANSFERASE
2wc7:A (PRO179) to (VAL211) CRYSTAL STRUCTURE OF NOSTOC PUNCTIFORME DEBRANCHING ENZYME( NPDE)(ACARBOSE SOAKED) | CD/PUL-HYDROLYZING ENZYMES, HYDROLASE, GLYCOSIDASE, NEOPULLULANSE
2wcg:A (SER351) to (TRP381) X-RAY STRUCTURE OF ACID-BETA-GLUCOSIDASE WITH N-OCTYL( CYCLIC GUANIDINE)-NOJIRIMYCIN IN THE ACTIVE SITE | LIPID METABOLISM, GLUCOCEREBROSIDASE, MEMBRANE, LYSOSOME, HYDROLASE, GLUCOSIDASE, GLYCOPROTEIN, GAUCHER DISEASE, SPHINGOLIPID METABOLISM
2wcg:B (SER351) to (TRP381) X-RAY STRUCTURE OF ACID-BETA-GLUCOSIDASE WITH N-OCTYL( CYCLIC GUANIDINE)-NOJIRIMYCIN IN THE ACTIVE SITE | LIPID METABOLISM, GLUCOCEREBROSIDASE, MEMBRANE, LYSOSOME, HYDROLASE, GLUCOSIDASE, GLYCOPROTEIN, GAUCHER DISEASE, SPHINGOLIPID METABOLISM
3iv2:B (ASN66) to (GLU86) CRYSTAL STRUCTURE OF MATURE APO-CATHEPSIN L C25A MUTANT | PROTEASE, MUTANT, APO, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, LYSOSOME, THIOL PROTEASE, ZYMOGEN
2wcz:B (LEU60) to (VAL83) 1.6A RESOLUTION STRUCTURE OF ARCHAEOGLOBUS FULGIDUS HJC, A HOLLIDAY JUNCTION RESOLVASE FROM AN ARCHAEAL HYPERTHERMOPHILE | TYPE II RESTRICTION ENDONUCLEASE, HYDROLASE, DNA BINDING PROTEIN, HOLLIDAY JUNCTION RESOLVASE
1tve:B (PHE241) to (LEU285) HOMOSERINE DEHYDROGENASE IN COMPLEX WITH 4-(4-HYDROXY-3- ISOPROPYLPHENYLTHIO)-2-ISOPROPYLPHENOL | ANTIFUNGAL; SMALL MOLECULE SCREENING; AMINO ACID BIOSYNTHESIS, OXIDOREDUCTASE
4lmd:B (HIS202) to (GLY226) CRYSTAL STRUCTURE OF THE JCV LARGE T-ANTIGEN ORIGIN BINDING DOMAIN | ORIGIN BINDING DOMAIN, DNA REPLICATION, HYDROLASE
2wiu:A (ALA116) to (LEU161) MERCURY-MODIFIED BACTERIAL PERSISTENCE REGULATOR HIPBA | TRANSFERASE TRANSCRIPTION COMPLEX, SERINE KINASE, DNA-BINDING, MERCURY DERIVATIVE, REPRESSOR, TRANSCRIPTION REGULATION, SAD
1hvx:A (TYR201) to (ALA235) BACILLUS STEAROTHERMOPHILUS ALPHA-AMYLASE | HYDROLASE, GLYCOSYLTRANSFERASE, ALPHA-AMYLASE,STARCH DEGRADATION, ALPHA-1,4-GLUCAN-4-GLUCANOHYDROLASE, THERMOSTABILITY
2wkl:A (SER351) to (TRP381) VELAGLUCERASE ALFA | ALTERNATIVE INITIATION, SPHINGOLIPID METABOLISM, MEMBRANE, LYSOSOME, HYDROLASE, ICHTHYOSIS, N-NONYL-DEOXYNOJIRIMYCIN, N-NONYL-DEOXYNOJIRIMYCIN ALTERNATIVE INITIATION, DISULFIDE BOND, PHARMACEUTICAL, GAUCHER DISEASE, GLYCOSIDASE, POLYMORPHISM, GLYCOPROTEIN, ALTERNATIVE SPLICING, ACID-BETA-GLUCOSIDASE, LIPID METABOLISM, DISEASE MUTATION, VELAGLUCERASE ALFA
2wkl:B (SER351) to (ASP380) VELAGLUCERASE ALFA | ALTERNATIVE INITIATION, SPHINGOLIPID METABOLISM, MEMBRANE, LYSOSOME, HYDROLASE, ICHTHYOSIS, N-NONYL-DEOXYNOJIRIMYCIN, N-NONYL-DEOXYNOJIRIMYCIN ALTERNATIVE INITIATION, DISULFIDE BOND, PHARMACEUTICAL, GAUCHER DISEASE, GLYCOSIDASE, POLYMORPHISM, GLYCOPROTEIN, ALTERNATIVE SPLICING, ACID-BETA-GLUCOSIDASE, LIPID METABOLISM, DISEASE MUTATION, VELAGLUCERASE ALFA
3vvg:B (GLY217) to (GLU252) THE CRYSTAL STRUCTURE OF CELLULASE-INHIBITOR COMPLEX. | CELLULASE INHIBITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vx0:A (SER172) to (THR207) CRYSTAL STRUCTURE OF ALPHA-AMYLASE FROM ASPERGILLUS ORYZAE | HYDROLASE
3vx1:A (SER172) to (THR207) CRYSTAL STRUCTURE OF ALPHA-AMYLASE FROM ASPERGILLUS ORYZAE | HYDROLASE
3w1i:B (ASN193) to (HIS215) CRYSTAL STRUCTURE OF THE N-TERMINAL TRUNCATED SELENOCYSTEINE SYNTHASE SELA | HOMODECAMER, PENTAMER OF DIMERS, FOLD-TYPE I PYRIDOXAL 5'-PHOSPHATE (PLP) DEPENDENT ENZYME, L-SERYL-TRNA(SEC) SELENIUM TRANSFERASE, SELENOCYSTEINE SYNTHESIS, SELENIUM METABOLISM, TRANSFERASE
3w1i:B (PHE224) to (ASP247) CRYSTAL STRUCTURE OF THE N-TERMINAL TRUNCATED SELENOCYSTEINE SYNTHASE SELA | HOMODECAMER, PENTAMER OF DIMERS, FOLD-TYPE I PYRIDOXAL 5'-PHOSPHATE (PLP) DEPENDENT ENZYME, L-SERYL-TRNA(SEC) SELENIUM TRANSFERASE, SELENOCYSTEINE SYNTHESIS, SELENIUM METABOLISM, TRANSFERASE
3w1i:C (ASN193) to (HIS215) CRYSTAL STRUCTURE OF THE N-TERMINAL TRUNCATED SELENOCYSTEINE SYNTHASE SELA | HOMODECAMER, PENTAMER OF DIMERS, FOLD-TYPE I PYRIDOXAL 5'-PHOSPHATE (PLP) DEPENDENT ENZYME, L-SERYL-TRNA(SEC) SELENIUM TRANSFERASE, SELENOCYSTEINE SYNTHESIS, SELENIUM METABOLISM, TRANSFERASE
3w1i:C (PHE224) to (ASP247) CRYSTAL STRUCTURE OF THE N-TERMINAL TRUNCATED SELENOCYSTEINE SYNTHASE SELA | HOMODECAMER, PENTAMER OF DIMERS, FOLD-TYPE I PYRIDOXAL 5'-PHOSPHATE (PLP) DEPENDENT ENZYME, L-SERYL-TRNA(SEC) SELENIUM TRANSFERASE, SELENOCYSTEINE SYNTHESIS, SELENIUM METABOLISM, TRANSFERASE
4lxz:A (ASP235) to (GLY267) STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH SAHA (VORINOSTAT) | DEACETYLASE, HISTONE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4lxz:C (ASP235) to (GLY267) STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH SAHA (VORINOSTAT) | DEACETYLASE, HISTONE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ly1:A (ASP235) to (GLY267) STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH INHIBITOR 4-(ACETYLAMINO)-N- [2-AMINO-5-(THIOPHEN-2-YL)PHENYL]BENZAMIDE | DEACETYLASE, HISTONE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2hxz:B (ASN67) to (ASP87) CRYSTAL STRUCTURE OF CATHEPSIN S IN COMPLEX WITH A NONPEPTIDIC INHIBITOR (HEXAGONAL SPACEGROUP) | CATHEPSIN S, NONPEPTIDIC, CHLOROMETHYLKETONE, SUBSTRATE ACTIVITY SCREENING, HYDROLASE
2hyb:C (GLY479) to (LEU502) CRYSTAL STRUCTURE OF HEXAMERIC DSREFH | DSRE, DSRF, DSRH, CRYSTAL STRUCTURE, SULFUR, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, BERKELEY STRUCTURAL GENOMICS CENTER, BSGC, TRANSFERASE
2hyb:F (GLY1479) to (LEU1502) CRYSTAL STRUCTURE OF HEXAMERIC DSREFH | DSRE, DSRF, DSRH, CRYSTAL STRUCTURE, SULFUR, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, BERKELEY STRUCTURAL GENOMICS CENTER, BSGC, TRANSFERASE
2hyb:I (GLY2479) to (LEU2502) CRYSTAL STRUCTURE OF HEXAMERIC DSREFH | DSRE, DSRF, DSRH, CRYSTAL STRUCTURE, SULFUR, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, BERKELEY STRUCTURAL GENOMICS CENTER, BSGC, TRANSFERASE
2hyb:L (GLY3479) to (LEU3502) CRYSTAL STRUCTURE OF HEXAMERIC DSREFH | DSRE, DSRF, DSRH, CRYSTAL STRUCTURE, SULFUR, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, BERKELEY STRUCTURAL GENOMICS CENTER, BSGC, TRANSFERASE
2hyb:O (GLY4479) to (LEU4502) CRYSTAL STRUCTURE OF HEXAMERIC DSREFH | DSRE, DSRF, DSRH, CRYSTAL STRUCTURE, SULFUR, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, BERKELEY STRUCTURAL GENOMICS CENTER, BSGC, TRANSFERASE
2hyb:R (GLY5479) to (LEU5502) CRYSTAL STRUCTURE OF HEXAMERIC DSREFH | DSRE, DSRF, DSRH, CRYSTAL STRUCTURE, SULFUR, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, BERKELEY STRUCTURAL GENOMICS CENTER, BSGC, TRANSFERASE
4lzi:A (GLY7) to (VAL41) CHARACTERIZATION OF SOLANUM TUBEROSUM MULTICYSTATIN AND SIGNIFICANCE OF CORE DOMAINS | CYSTATIN, HYDROLASE INHIBITOR
1ud2:A (GLY198) to (ALA232) CRYSTAL STRUCTURE OF CALCIUM-FREE ALPHA-AMYLASE FROM BACILLUS SP. STRAIN KSM-K38 (AMYK38) | CALCIUM-FREE, ALKALINE, ALPHA-AMYLASE, HYDROLASE
1ud3:A (GLY198) to (ALA232) CRYSTAL STRUCTURE OF AMYK38 N289H MUTANT | CALCIUM-FREE, ALKALINE, ALPHA-AMYLASE, HYDROLASE
1ud4:A (GLY198) to (ALA232) CRYSTAL STRUCTURE OF CALCIUM FREE ALPHA AMYLASE FROM BACILLUS SP. STRAIN KSM-K38 (AMYK38, IN CALCIUM CONTAINING SOLUTION) | CALCIUM-FREE, ALKALINE, ALPHA-AMYLASE, HYDROLASE
1ud6:A (GLY198) to (ALA232) CRYSTAL STRUCTURE OF AMYK38 WITH POTASSIUM ION | CALCIUM-FREE, ALKALINE, ALPHA-AMYLASE, HYDROLASE
1icp:A (VAL81) to (ILE111) CRYSTAL STRUCTURE OF 12-OXOPHYTODIENOATE REDUCTASE 1 FROM TOMATO COMPLEXED WITH PEG400 | BETA-ALPHA-BARREL, PROTEIN-FMN-PEG COMPLEX, OXIDOREDUCTASE
1icp:B (VAL81) to (ILE111) CRYSTAL STRUCTURE OF 12-OXOPHYTODIENOATE REDUCTASE 1 FROM TOMATO COMPLEXED WITH PEG400 | BETA-ALPHA-BARREL, PROTEIN-FMN-PEG COMPLEX, OXIDOREDUCTASE
1ics:A (VAL81) to (ILE111) CRYSTAL STRUCTURE OF 12-OXOPHYTODIENOATE REDUCTASE 1 FROM TOMATO | BETA-ALPHA-BARREL, OXIDOREDUCTASE
1icq:A (VAL81) to (ILE111) CRYSTAL STRUCTURE OF 12-OXOPHYTODIENOATE REDUCTASE 1 FROM TOMATO COMPLEXED WITH 9R,13R-OPDA | BETA-ALPHA-BARREL, PROTEIN-FMN-(9R,13R-OPDA)-COMPLEX, FMN- SUBSTRATE-COMPLEX, OXIDOREDUCTASE
1igw:A (LYS201) to (THR233) CRYSTAL STRUCTURE OF THE ISOCITRATE LYASE FROM THE A219C MUTANT OF ESCHERICHIA COLI | BETA BARREL, LYASE
1igw:B (LYS201) to (THR233) CRYSTAL STRUCTURE OF THE ISOCITRATE LYASE FROM THE A219C MUTANT OF ESCHERICHIA COLI | BETA BARREL, LYASE
2i4n:B (ILE39) to (LEU70) RHODOPSEUDOMONAS PALUSTRIS PROLYL-TRNA SYNTHETASE IN COMPLEX WITH CYSAMS | ALPHA BETA, LIGASE
2i4o:B (ILE39) to (LEU70) RHODOPSEUDOMONAS PALUSTRIS PROLYL-TRNA SYNTHETASE IN COMPLEX WITH ATP | ALPHA BETA, LIGASE
2ieb:A (GLY229) to (TYR259) CRYSTAL STRUCTURE OF ISONIAZID-RESISTANT S94A ENOYL-ACP(COA) REDUCTASE MUTANT ENZYME FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH NADH- INH | ENOYL-ACYL CARRIER PROTEIN, INHA, OXIDOREDUCTASE
1itq:A (ASN260) to (ASP288) HUMAN RENAL DIPEPTIDASE | DIPEPTIDASE, GLYCOPROTEIN, MEMBRANE-BOUND, ZINC PROTEASE BETA- LACTAMASE, CILASTATIN, COMPLEX (HYDROLASE-INHIBITOR), HYDROLASE
1itq:B (ASN260) to (ASP288) HUMAN RENAL DIPEPTIDASE | DIPEPTIDASE, GLYCOPROTEIN, MEMBRANE-BOUND, ZINC PROTEASE BETA- LACTAMASE, CILASTATIN, COMPLEX (HYDROLASE-INHIBITOR), HYDROLASE
1itu:A (ASN260) to (ASP288) HUMAN RENAL DIPEPTIDASE COMPLEXED WITH CILASTATIN | DIPEPTIDASE, GLYCOPROTEIN, MEMBRANE-BOUND, ZINC PROTEASE BETA- LACTAMASE, CILASTATIN, COMPLEX (HYDROLASE-INHIBITOR), HYDROLASE
1itu:B (ASN260) to (ASP288) HUMAN RENAL DIPEPTIDASE COMPLEXED WITH CILASTATIN | DIPEPTIDASE, GLYCOPROTEIN, MEMBRANE-BOUND, ZINC PROTEASE BETA- LACTAMASE, CILASTATIN, COMPLEX (HYDROLASE-INHIBITOR), HYDROLASE
4m9j:A (LYS148) to (VAL177) DNA POLYMERASE BETA E295K SOAKED WITH DUMPNPP | DNA POLYMERASE, LYASE, DNA COMPLEX, TRANSFERASE-DNA COMPLEX
2if9:A (HIS201) to (LYS224) CRYSTAL STRUCTURE OF SV40 T-ANTIGEN ORIGIN BINDING DOMAIN DISULFIDE-LINKED DIMER | ORIGIN BINDING DOMAIN, VIRAL PROTEIN
1usy:E (ASP147) to (ASP164) ATP PHOSPHORIBOSYL TRANSFERASE (HISG:HISZ) COMPLEX FROM THERMOTOGA MARITIMA | TRANSFERASE, ATP PHOSPHORIBOSYL TRANSFERASE, AMINOACYL-TRNA SYNTHETASE
1usy:H (ASP147) to (ASP164) ATP PHOSPHORIBOSYL TRANSFERASE (HISG:HISZ) COMPLEX FROM THERMOTOGA MARITIMA | TRANSFERASE, ATP PHOSPHORIBOSYL TRANSFERASE, AMINOACYL-TRNA SYNTHETASE
1ixg:A (LYS215) to (ASN243) PHOSPHATE-BINDING PROTEIN MUTANT WITH THR 141 REPLACED BY ASP (T141D), COMPLEXED WITH PHOSPATE | PHOSPHATE TRANSPORT, ULTRA HIGH RESOLUTION, PHOSPHATE BINDIN PROTEIN
1ixh:A (LYS215) to (ASN243) PHOSPHATE-BINDING PROTEIN (PBP) COMPLEXED WITH PHOSPHATE | PHOSPHATE TRANSPORT, ULTRA HIGH RESOLUTION, PHOSPHATE BINDIN PROTEIN
1ixk:A (THR83) to (GLU104) CRYSTAL STRUCTURE ANALYSIS OF METHYLTRANSFERASE HOMOLOG PROTEIN FROM PYROCOCCUS HORIKOSHII | OPEN BETA SHEET, TRANSFERASE
5aeg:A (PRO336) to (GLU366) A BACTERIAL PROTEIN STUCTURE IN GLYCOSIDE HYDROLASE FAMILY 31. | HYDROLASE, GH31, ALPHA-SULFOQUINOVOSIDASE
5aeg:A (GLU369) to (ASP405) A BACTERIAL PROTEIN STUCTURE IN GLYCOSIDE HYDROLASE FAMILY 31. | HYDROLASE, GH31, ALPHA-SULFOQUINOVOSIDASE
4mfb:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH 8-(2- (2-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)ETHOXY)PHENOXY) INDOLIZINE-2-CARBONITRILE (JLJ555), A NON-NUCLEOSIDE INHIBITOR | POLYMERASE, TRANSFERASE, HYDROLASE, RNASEH, RNASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4mgr:C (ASP240) to (VAL258) THE CRYSTAL STRUCTURE OF BACILLUS SUBTILIS GABR, AN AUTOREPRESSOR AND PLP- AND GABA-DEPENDENT TRANSCRIPTIONAL ACTIVATOR OF GABT | WINGED HELIX TURN HELIX, TYPE-I AMINOTRANSFERASE, TRANSCRIPTION REGULATOR, PLP BINDING, DNA BINDING
2ipr:B (HIS201) to (LYS224) ORIGIN BINDING DOMAIN OF THE SV40 LARGE T ANTIGEN (RESIDUES 131-259). P21 CRYSTAL FORM | DNA BINDING PROTEIN
1v1p:B (GLU140) to (LYS176) THE STRUCTURE SSL FROM STAPHYLOCOCCUS AUREUS FROM AN ORTHORHOMBIC CRYSTAL FORM | VIRULENCE FACTOR, ANTIGEN PRESENTING CELL, SECRETED PROTEIN, STAPHYLOCOCCAL EXOTOXIN 1, SET1, SUPERANTIGEN, OB-FOLD, {BETA}-GRASP
2iru:A (GLY89) to (PRO116) CRYSTAL STRUCTURE OF THE POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D | POLYMERASE, PRIMASE, LIGASE, NHEJ, TRANSFERASE
3wkt:B (LYS130) to (GLY165) COMPLEX STRUCTURE OF AN OPEN FORM OF NADPH-CYTOCHROME P450 REDUCTASE AND HEME OXYGENASE-1 | HEME DEGRADATION, MICROSOMAL MEMBRANE, OXIDOREDUCTASE
2ivd:B (ASN63) to (ALA88) STRUCTURE OF PROTOPORPHYRINOGEN OXIDASE FROM MYXOCOCCUS XANTHUS WITH ACIFLUORFEN | PROTOPORPHYRINOGEN OXIDASE, PORPHYRIN BIOSYNTHESIS, CHLOROPHYLL BIOSYNTHESIS, OXIDOREDUCTASE, HAEM BIOSYNTHESIS, HEME BIOSYNTHESIS, FAD, PORPHYRIA, ACIFLUORFEN, FLAVOPROTEIN
4mky:B (GLY89) to (PRO116) POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D IN COMPLEX WITH AN ANNEALED DOUBLE-STRAND DNA BREAK. | PROTEIN-DNA COMPLEX, TRANSFERASE-DNA COMPLEX, NUCLEOTIDE-BINDING, POLYMERASE, PRIMASE, TRANSFERASE
1vdm:E (LYS3) to (VAL33) CRYSTAL STRUCTURE OF PURINE PHOSPHORIBOSYLTRANSFERASE FROM PYROCOCCUS HORIKOSHII OT3 | PURINE PHOSPHORIBOSYLTRANSFERASE, PYROCOCCUS HORIKOSHII, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
1vdm:J (LYS3) to (VAL33) CRYSTAL STRUCTURE OF PURINE PHOSPHORIBOSYLTRANSFERASE FROM PYROCOCCUS HORIKOSHII OT3 | PURINE PHOSPHORIBOSYLTRANSFERASE, PYROCOCCUS HORIKOSHII, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2j25:B (SER351) to (TRP381) PARTIALLY DEGLYCOSYLATED GLUCOCERAMIDASE | PHARMACEUTICAL, GAUCHER DISEASE, DISEASE MUTATION, GLYCOSIDASE, SPHINGOLIPID, POLYMORPHISM, GLYCOPROTEIN, MEMBRANE, LYSOSOME, HYDROLASE, GLUCOSIDASE, GLUCOCEREBROSIDASE, ALTERNATIVE INITIATION, LIPID METABOLISM, CEREZYME HYDROLASE, SPHINGOLIPID METABOLISM
4mq9:D (GLY1163) to (ARG1189) CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH GE23077 | DNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSFERASE-ANTIBIOTIC COMPLEX
1jlf:A (HIS361) to (LYS390) CRYSTAL STRUCTURE OF Y188C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NON-NUCLEOSIDE INHIBITOR, NEVIRAPINE, DRUG RESISTANCE MUTATIONS, DRUG DESIGN, TRANSFERASE
1jlq:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH 739W94 | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NON-NUCLEOSIDE INHIBITOR, 739W94, DRUG DESIGN, TRANSFERASE
1jrp:F (GLY484) to (ALA515) CRYSTAL STRUCTURE OF XANTHINE DEHYDROGENASE INHIBITED BY ALLOXANTHINE FROM RHODOBACTER CAPSULATUS | PARTIAL BETA-BARREL; XDH; XO, OXIDOREDUCTASE
1vru:A (ALA360) to (LYS390) HIGH RESOLUTION STRUCTURES OF HIV-1 RT FROM FOUR RT- INHIBITOR COMPLEXES | HIV-1 REVERSE TRANSCRIPTASE, NUCLEOTIDYLTRANSFERASE
5axm:A (THR76) to (ALA117) CRYSTAL STRUCTURE OF THG1 LIKE PROTEIN (TLP) WITH TRNA(PHE) | TRANSFERASE, TRANSFERASE-RNA COMPLEX
5axn:B (THR76) to (ALA117) CRYSTAL STRUCTURE OF THG1 LIKE PROTEIN (TLP) WITH TRNA(PHE) AND GDPNP | TRANSFERASE, TRANSFERASE-RNA COMPLEX
1vyp:X (ALA71) to (ARG106) STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE W102F MUTANT AND COMPLEXED WITH PICRIC ACID | OXIDOREDUCTASE, FLAVOENZYME, EXPLOSIVE DEGRADATION, STEROID BINDING
1vyr:A (THR147) to (HIS181) STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE COMPLEXED WITH PICRIC ACID | OXIDOREDUCTASE, FLAVOENZYME, EXPLOSIVE DEGRADATION, STEROID BINDING
1vys:X (ALA71) to (ARG106) STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE W102Y MUTANT AND COMPLEXED WITH PICRIC ACID | FLAVOENZYME, EXPLOSIVE DEGRADATION, STEROID BINDING, OXIDOREDUCTASE
4n7j:A (ALA132) to (GLN161) TAILORING SMALL MOLECULES FOR AN ALLOSTERIC SITE ON PROCASPASE-6 | PROCASPSE-6, CASPASE-6 ZYMOGEN, ALLOSTERIC, STRUCTURE BASED DRUG DESIGN, CASPASE, CYSTEINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2xu1:D (ASN66) to (GLU86) CATHEPSIN L WITH A NITRILE INHIBITOR | HYDROLASE, DRUG DESIGN, THIOL PROTEASE
2xu5:A (ASN66) to (GLU86) CATHEPSIN L WITH A NITRILE INHIBITOR | HYDROLASE, DRUG DESIGN, THIOL PROTEASE
1k03:A (ALA85) to (LEU115) CRYSTAL STRUCTURE OF OLD YELLOW ENZYME MUTANT GLN114ASN COMPLEXED WITH PARA-HYDROXY BENZALDEHYDE | BETA-ALPHA BARRELS, OXIDOREDUCTASE
2xwd:A (SER351) to (TRP381) X-RAY STRUCTURE OF ACID-BETA-GLUCOSIDASE WITH 5N,6O-(N'-(N- OCTYL)IMINO)NOJIRIMYCIN IN THE ACTIVE SITE | GLUCOCEREBROSIDASE, HYDROLASE, GAUCHER DISEASE, SPHINGOLIPID METABOLISM
2xwd:B (SER351) to (TRP381) X-RAY STRUCTURE OF ACID-BETA-GLUCOSIDASE WITH 5N,6O-(N'-(N- OCTYL)IMINO)NOJIRIMYCIN IN THE ACTIVE SITE | GLUCOCEREBROSIDASE, HYDROLASE, GAUCHER DISEASE, SPHINGOLIPID METABOLISM
2xwe:A (SER351) to (TRP381) X-RAY STRUCTURE OF ACID-BETA-GLUCOSIDASE WITH 5N,6S-(N'-(N- OCTYL)IMINO)-6-THIONOJIRIMYCIN IN THE ACTIVE SITE | GLUCOCEREBROSIDASE, HYDROLASE, GAUCHER DISEASE, SPHINGOLIPID METABOLISM
2xwe:B (SER351) to (TRP381) X-RAY STRUCTURE OF ACID-BETA-GLUCOSIDASE WITH 5N,6S-(N'-(N- OCTYL)IMINO)-6-THIONOJIRIMYCIN IN THE ACTIVE SITE | GLUCOCEREBROSIDASE, HYDROLASE, GAUCHER DISEASE, SPHINGOLIPID METABOLISM
1k1x:A (VAL125) to (VAL144) CRYSTAL STRUCTURE OF 4-ALPHA-GLUCANOTRANSFERASE FROM THERMOCOCCUS LITORALIS | 4-ALPHA-GLUCANOTRANSFERASE, TRANSFERASE
1k1y:A (VAL125) to (VAL144) CRYSTAL STRUCTURE OF THERMOCOCCUS LITORALIS 4-ALPHA-GLUCANOTRANSFERASE COMPLEXED WITH ACARBOSE | 4-ALPHA-GLUCANOTRANSFERASE COMPLEXED WITH ACARBOSE, TRANSFERASE
1w9x:A (TYR203) to (ALA237) BACILLUS HALMAPALUS ALPHA AMYLASE | HYDROLASE, AMYLASE, ACARBOSE, BACILLUS, GLYCOSIDE HYDROLASE
1wam:A (TYR313) to (GLY342) STRUCTURE OF UDP-GALACTOPYRANOSE MUTASE FROM KLEBSIELLA PNEUMONIAE WITH FADH- | FAD, FLAVOPROTEIN, ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS
1wnh:A (PHE-1) to (VAL34) CRYSTAL STRUCTURE OF MOUSE LATEXIN (TISSUE CARBOXYPEPTIDASE INHIBITOR) | BI-CYSTATIN FOLD, CIS-PROLINE, HYDROLASE INHIBITOR
1wnh:A (PRO116) to (MET160) CRYSTAL STRUCTURE OF MOUSE LATEXIN (TISSUE CARBOXYPEPTIDASE INHIBITOR) | BI-CYSTATIN FOLD, CIS-PROLINE, HYDROLASE INHIBITOR
2kjw:A (PRO54) to (LEU85) SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF THE PERMUTANT P54-55 | S6 PERMUTANT, SOLUTION STRUCTURE, BACKBONE DYNAMICS, FOLDING, RIBONUCLEOPROTEIN, RIBOSOMAL PROTEIN, RNA-BINDING, RRNA-BINDING
1wp6:A (TYR203) to (ALA237) CRYSTAL STRUCTURE OF MALTOHEXAOSE-PRODUCING AMYLASE FROM ALKALOPHILIC BACILLUS SP.707. | ALPHA-AMYLASE, MALTOHEXAOSE, HYDROLASE
1wpc:A (TYR203) to (ALA237) CRYSTAL STRUCTURE OF MALTOHEXAOSE-PRODUCING AMYLASE COMPLEXED WITH PSEUDO-MALTONONAOSE | MALTOHEXAOSE-PRODUCING AMYLASE, ALPHA-AMYLASE, ACARBOSE, HYDROLASE
4nmn:A (PRO290) to (ASP316) AQUIFEX AEOLICUS REPLICATIVE HELICASE (DNAB) COMPLEXED WITH ADP, AT 3.3 RESOLUTION | RECA-TYPE HELICASE, REPLICATIVE DNA HELICASE, ATP BINDING, DNA- BINDING, REPLICATION
5c24:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH 7- ((4-((4-CYANOPHENYL)AMINO)-1,3,5-TRIAZIN-2-YL)AMINO)-6,8- DIMETHYLINDOLIZINE-2-CARBONITRILE (JLJ605), A NON-NUCLEOSIDE INHIBITOR | HIV, REVERSE TRANSCRIPTASE, NON-NUCLEOSIDE INHIBITOR, INDOLIZINE, TRIAZINE, POLYMERASE, TRANSFERASE, HYDROLASE-INHIBITOR COMPLEX
5c25:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH 6- ((4-((4-CYANOPHENYL)AMINO)-1,3,5-TRIAZIN-2-YL)AMINO)-5,7-DIMETHYL-2- NAPHTHONITRILE (JLJ639), A NON-NUCLEOSIDE INHIBITOR | POLYMERASE, REVERSE TRANSCRIPTASE, HIV, NON-NUCLEOSIDE INHIBITOR, TRANSFERASE, HYDROLASE-DNA-INHIBITOR COMPLEX, HYDROLASE-INHIBITOR COMPLEX
1wwl:A (GLY214) to (LEU237) CRYSTAL STRUCTURE OF CD14 | CD14, LPS, IMMUNE SYSTEM
1kjx:A (ARG304) to (LYS331) IMP COMPLEX OF E. COLI ADENYLOSUCCINATE SYNTHETASE | LIGASE, GTP-HYDROLYSING ENZYMES, PURINE NUCLEOTIDE BIOSYNTHESIS, INDUCED FIT, IMP
1klm:A (HIS361) to (PRO392) HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH BHAP U-90152 | AIDS, HIV-1, ENDONUCLEASE, RNA-DIRECTED DNA POLYMERASE, HIV-1 REVERSE TRANSCRIPTASE, BHAP U-90152, DRUG, NUCLEOTIDYLTRANSFERASE
4nzc:A (TYR371) to (GLU396) CRYSTAL STRUCTURE OF CHITINASE D FROM SERRATIA PROTEAMACULANS AT 1.45 ANGSTROM RESOLUTION | CHITINASE D,TIM BARREL, TRANSGLYCOSYLATION, HYDROLASE
4o1n:E (GLU131) to (MET166) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN SAOUHSC_00383 | OLIGOSACCHARIDE-BINDING, BETA-GRASP DOMAIN, SUGAR BINDING PROTEIN
2nsx:B (SER351) to (TRP381) STRUCTURE OF ACID-BETA-GLUCOSIDASE WITH PHARMACOLOGICAL CHAPERONE PROVIDES INSIGHT INTO GAUCHER DISEASE | TIM-BARREL GLYCOSIDASE CEREZYME HYDROLYSIS, HYDROLASE
2nsx:D (SER351) to (TRP381) STRUCTURE OF ACID-BETA-GLUCOSIDASE WITH PHARMACOLOGICAL CHAPERONE PROVIDES INSIGHT INTO GAUCHER DISEASE | TIM-BARREL GLYCOSIDASE CEREZYME HYDROLYSIS, HYDROLASE
2nt0:A (SER351) to (TRP381) ACID-BETA-GLUCOSIDASE LOW PH, GLYCEROL BOUND | CEREZYME, GLUCOCEREBROSIDASE, GLUCOSYLCERAMIDE, HYDROLYSIS, GAUCHER DISEASE, HYDROLASE
2nt0:B (SER351) to (TRP381) ACID-BETA-GLUCOSIDASE LOW PH, GLYCEROL BOUND | CEREZYME, GLUCOCEREBROSIDASE, GLUCOSYLCERAMIDE, HYDROLYSIS, GAUCHER DISEASE, HYDROLASE
2nt0:C (SER351) to (TRP381) ACID-BETA-GLUCOSIDASE LOW PH, GLYCEROL BOUND | CEREZYME, GLUCOCEREBROSIDASE, GLUCOSYLCERAMIDE, HYDROLYSIS, GAUCHER DISEASE, HYDROLASE
2nt0:D (SER351) to (TRP381) ACID-BETA-GLUCOSIDASE LOW PH, GLYCEROL BOUND | CEREZYME, GLUCOCEREBROSIDASE, GLUCOSYLCERAMIDE, HYDROLYSIS, GAUCHER DISEASE, HYDROLASE
3jsn:A (GLY83) to (LEU111) CRYSTAL STRUCTURE OF THE ADENYLATION DOMAIN OF NAD+- DEPENDENT DNA LIGASE FROM STAPHYLOCOCCUS AUREUS | NAD+-DEPENDENT DNA LIGASE, ADENYLATION DOMAIN, STAPHYLOCOCCUS AUREUS, DNA DAMAGE, DNA REPAIR, DNA REPLICATION, LIGASE, MAGNESIUM, MANGANESE, METAL-BINDING, NAD, ZINC
2ync:A (LEU277) to (GLU294) PLASMODIUM VIVAX N-MYRISTOYLTRANSFERASE IN COMPLEX WITH YNC12-COA THIOESTER. | TRANSFERASE, MYRISTOYLATION, MALARIA
2ynd:A (LEU277) to (GLU294) PLASMODIUM VIVAX N-MYRISTOYLTRANSFERASE IN COMPLEX WITH A PYRAZOLE SULPHONAMIDE INHIBITOR. | TRANSFERASE, MYRISTOYLATION, MALARIA, PYRAZOLE SULPHONAMIDE
1xhl:B (GLY101) to (VAL144) CRYSTAL STRUCTURE OF PUTATIVE TROPINONE REDUCTASE-II FROM CAENORHABDITIS ELEGANS WITH COFACTOR AND SUBSTRATE | PARALLEL BETA-SHEET OF SEVEN STRANDS IN THE ORDER 3214567, THREE ALPHA-HELICES ON EITHER SIDE OF BETA-SHEET, SEVENTH ALPHA-HELIX ON TOP OF BETA-SHEET, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, SCSG, PSI, SOUTHEAST COLLABORATORY FOR STRUCTURAL GENOMICS, SECSG, OXIDOREDUCTASE
2nvy:B (LYS403) to (LYS451) RNA POLYMERASE II FORM II IN 150 MM MN+2 | TRANSCRIPTION, MRNA, MULTIPROTEIN COMPLEX, MOLECULAR MACHINE, DNA
2z22:X (LYS215) to (ASN243) CRYSTAL STRUCTURE OF PHOSPHATE PREPLASMIC BINDING PROTEIN PSTS FROM YERSINIA PESTIS | ABC TRANSPORTER, PHOSPHATE PERIPLASMIC BINDING RECEPTOR, TRANSPORT PROTEIN,IMMUNE SYSTEM
2z22:A (LYS215) to (ASN243) CRYSTAL STRUCTURE OF PHOSPHATE PREPLASMIC BINDING PROTEIN PSTS FROM YERSINIA PESTIS | ABC TRANSPORTER, PHOSPHATE PERIPLASMIC BINDING RECEPTOR, TRANSPORT PROTEIN,IMMUNE SYSTEM
2o1b:A (GLY175) to (HIS199) STRUCTURE OF AMINOTRANSFERASE FROM STAPHYLOCOCCUS AUREUS | AMINOTRASFERASE, CLASS I, TRANSFERASE
2o1w:C (ASP520) to (GLY543) STRUCTURE OF N-TERMINAL PLUS MIDDLE DOMAINS (N+M) OF GRP94 | GRP94, HSP82, HSP90, HTPG, CHAPERONE, GP96, ENDOPLASMIN,
1xja:C (HIS18) to (LEU40) APO FORM OF THE Y31V MUTANT DIMERIZATION DOMAIN FRAGMENT OF ESCHERICHIA COLI REGULATORY PROTEIN ARAC | TRANSCRIPTION FACTOR, COILED-COIL, JELLY ROLL, ALLOSTERY, ARABINOSE, CARBOHYDRATE BINDING, ARAC, TRANSCRIPTION
4oip:D (GLY1163) to (ARG1189) CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS TRANSCRIPTION INITIATION COMPLEX SOAKED WITH GE23077, ATP, AND CMPCPP | GE23077, TRANSCRIPTION INHIBITOR, TRANSCRIPTION OPEN COMPLEX, TRANSCRIPTION INITIATION COMPLEX, I SITE, I+1 SITE, CMPCPP, RNA POLYMERASE, DNA/RNA/NTP BINDING, POLYMERIZATION OF RIBONUCLEOTIDES, NUCLEOID, TRANSCRIPTION, TRANSFERASE-ANTIBIOTIC COMPLEX
2o56:B (GLN184) to (MET220) CRYSTAL STRUCTURE OF A MEMBER OF THE ENOLASE SUPERFAMILY FROM SALMONELLA TYPHIMURIUM | DEHYDRATASE, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI- 2, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, UNKNOWN FUNCTION
2o56:F (GLN184) to (MET220) CRYSTAL STRUCTURE OF A MEMBER OF THE ENOLASE SUPERFAMILY FROM SALMONELLA TYPHIMURIUM | DEHYDRATASE, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI- 2, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, UNKNOWN FUNCTION
2o56:G (GLN184) to (MET220) CRYSTAL STRUCTURE OF A MEMBER OF THE ENOLASE SUPERFAMILY FROM SALMONELLA TYPHIMURIUM | DEHYDRATASE, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI- 2, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, UNKNOWN FUNCTION
5cr7:B (PHE125) to (ASN154) HUMAN CYTOSOLIC 5'-NUCLEOTIDASE II IN COMPLEX WITH N-(9H-PURIN-6-YL)- 3-(3-PYRROL-1-YLPHENYL)BENZAMIDE | COMPLEX, HYDROLASE
1xnv:A (GLY178) to (VAL197) ACYL-COA CARBOXYLASE BETA SUBUNIT FROM S. COELICOLOR (PCCB), APO FORM #1 | POLYKETIDE; POLYKETIDE SYNTHASE; ACYL-COA CARBOXYLASE; CARBOXYLTRANSFERASE, LIGASE
1xny:A (GLY178) to (VAL197) BIOTIN AND PROPIONYL-COA BOUND TO ACYL-COA CARBOXYLASE BETA SUBUNIT FROM S. COELICOLOR (PCCB) | POLYKETIDE; POLYKETIDE SYNTHASE; ACYL-COA CARBOXYLASE; CARBOXYLTRANSFERASE, LIGASE
1xny:B (GLY178) to (VAL197) BIOTIN AND PROPIONYL-COA BOUND TO ACYL-COA CARBOXYLASE BETA SUBUNIT FROM S. COELICOLOR (PCCB) | POLYKETIDE; POLYKETIDE SYNTHASE; ACYL-COA CARBOXYLASE; CARBOXYLTRANSFERASE, LIGASE
2zd1:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH TMC278 (RILPIVIRINE), A NON-NUCLEOSIDE RT INHIBITOR | P51/P66, HETERO DIMER, NNRTI, NONNUCLEOSIDE INHIBITOR, AIDS, HIV, R278474, RILPIVIRINE, DIARYLPYRIMIDINE, DAPY, DNA RECOMBINATION, RNA-DIRECTED DNA POLYMERASE, DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MULTIFUNCTIONAL ENZYME, TRANSFERASE, HYDROLASE-INHIBITOR COMPLEX
2ze2:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF L100I/K103N MUTANT HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH TMC278 (RILPIVIRINE), A NON-NUCLEOSIDE RT INHIBITOR | P51/P66, HETERO DIMER, NNRTI, NONNUCLEOSIDE INHIBITOR, AIDS, HIV, R278474, RILPIVIRINE, DIARYLPYRIMIDINE, DAPY, DNA RECOMBINATION, RNA-DIRECTED DNA POLYMERASE, DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MULTIFUNCTIONAL ENZYME, TRANSFERASE
1m1o:D (ASP251) to (GLY273) CRYSTAL STRUCTURE OF BIOSYNTHETIC THIOLASE, C89A MUTANT, COMPLEXED WITH ACETOACETYL-COA | THIOLASE FOLD, TRANSFERASE
3ke0:A (SER351) to (TRP381) CRYSTAL STRUCTURE OF N370S GLUCOCEREBROSIDASE AT ACIDIC PH. | TIM BARREL, ALTERNATIVE INITIATION, DISEASE MUTATION, DISULFIDE BOND, GAUCHER DISEASE, GLYCOPROTEIN, GLYCOSIDASE, HYDROLASE, ICHTHYOSIS, LIPID METABOLISM, LYSOSOME, MEMBRANE, SPHINGOLIPID METABOLISM
3ke0:B (SER351) to (TRP381) CRYSTAL STRUCTURE OF N370S GLUCOCEREBROSIDASE AT ACIDIC PH. | TIM BARREL, ALTERNATIVE INITIATION, DISEASE MUTATION, DISULFIDE BOND, GAUCHER DISEASE, GLYCOPROTEIN, GLYCOSIDASE, HYDROLASE, ICHTHYOSIS, LIPID METABOLISM, LYSOSOME, MEMBRANE, SPHINGOLIPID METABOLISM
3keh:B (SER351) to (TRP381) CRYSTAL STRUCTURE OF N370S GLUCOCEREBROSIDASE MUTANT AT PH 7.4 | GLUCOCEREBROSIDASE, ACID-BETA-GLUCOSIDASE, N370S, GLUCOSYCEREMIDASE, TIM BARREL, ALTERNATIVE INITIATION, DISEASE MUTATION, DISULFIDE BOND, GAUCHER DISEASE, GLYCOPROTEIN, GLYCOSIDASE, HYDROLASE, ICHTHYOSIS, LIPID METABOLISM, LYSOSOME, MEMBRANE, SPHINGOLIPID METABOLISM
3kft:A (ALA71) to (ARG106) CRYSTAL STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE COMPLEX WITH 1,4,5,6-TETRAHYDRO NADH | NADH:FLAVIN OXIDOREDUCTASE / NADH OXIDASE FAMILY
5cyn:A (HIS202) to (GLY226) JC VIRUS LARGE T-ANTIGEN ORIGIN BINDING DOMAIN F258L MUTANT | DNA BINDING DOMAIN, ORIGIN BINDING DOMAIN, VIRAL PROTEIN, DNA BINDING PROTEIN
4acy:A (THR297) to (ILE324) SELENOMETHIONINE DERIVATIVE OF THE GH99 ENDO-ALPHA- MANNOSIDASE FROM BACTEROIDES THETAIOTAOMICRON | HYDROLASE, ENDOMANNOSIDASE, GLYCOSIDE HYDROLASE, CAZY, ENZYME-CARBOHYDRATE INTERACTION, MANNOSE, GLYCOSIDASE INHIBITION
4acy:B (THR297) to (ILE324) SELENOMETHIONINE DERIVATIVE OF THE GH99 ENDO-ALPHA- MANNOSIDASE FROM BACTEROIDES THETAIOTAOMICRON | HYDROLASE, ENDOMANNOSIDASE, GLYCOSIDE HYDROLASE, CAZY, ENZYME-CARBOHYDRATE INTERACTION, MANNOSE, GLYCOSIDASE INHIBITION
4acz:A (THR297) to (ILE324) STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES THETAIOTAOMICRON | HYDROLASE, ENDOMANNOSIDASE, GLYCOSIDE HYDROLASE GH99, CAZY, ENZYME-CARBOHYDRATE INTERACTION, MANNOSE GLYCOSIDASE INHIBITION
4acz:B (THR297) to (ILE324) STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES THETAIOTAOMICRON | HYDROLASE, ENDOMANNOSIDASE, GLYCOSIDE HYDROLASE GH99, CAZY, ENZYME-CARBOHYDRATE INTERACTION, MANNOSE GLYCOSIDASE INHIBITION
4ad1:A (VAL301) to (THR329) STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS | HYDROLASE, GLYCOSIDE HYDROLASE GH99, CAZY, ENZYME-CARBOHYDRATE INTERACTION, MANNOSE GLYCOSIDASE INHIBITION
4ad2:A (VAL301) to (SER330) STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH GLUCOSE-1,3-ISOFAGOMINE | HYDROLASE, ENDOMANNOSIDASE, GLYCOSIDE HYDROLASE GH99, CAZY, ENZYME-CARBOHYDRATE INTERACTION, MANNOSE GLYCOSIDASE INHIBITION
4ad2:B (VAL301) to (THR329) STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH GLUCOSE-1,3-ISOFAGOMINE | HYDROLASE, ENDOMANNOSIDASE, GLYCOSIDE HYDROLASE GH99, CAZY, ENZYME-CARBOHYDRATE INTERACTION, MANNOSE GLYCOSIDASE INHIBITION
4ad2:C (VAL301) to (THR329) STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH GLUCOSE-1,3-ISOFAGOMINE | HYDROLASE, ENDOMANNOSIDASE, GLYCOSIDE HYDROLASE GH99, CAZY, ENZYME-CARBOHYDRATE INTERACTION, MANNOSE GLYCOSIDASE INHIBITION
4ad3:A (VAL301) to (THR329) STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH GLUCOSE-1,3- DEOXYMANNOJIRIMYCIN | HYDROLASE, GLYCOSIDE HYDROLASE, GH99, CAZY, ENZYME-CARBOHYDRATE INTERACTION, MANNOSE GLYCOSIDASE INHIBITION
4ad3:B (VAL301) to (THR329) STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH GLUCOSE-1,3- DEOXYMANNOJIRIMYCIN | HYDROLASE, GLYCOSIDE HYDROLASE, GH99, CAZY, ENZYME-CARBOHYDRATE INTERACTION, MANNOSE GLYCOSIDASE INHIBITION
4ad3:C (VAL301) to (THR329) STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH GLUCOSE-1,3- DEOXYMANNOJIRIMYCIN | HYDROLASE, GLYCOSIDE HYDROLASE, GH99, CAZY, ENZYME-CARBOHYDRATE INTERACTION, MANNOSE GLYCOSIDASE INHIBITION
4ad4:A (VAL301) to (THR329) STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH GLUCOSE-1,3- ISOFAGOMINE AND ALPHA-1,2-MANNOBIOSE | HYDROLASE, ENDOMANNOSIDASE, GLYCOSIDE HYDROLASE, GH99, CAZY, ENZYME-CARBOHYDRATE INTERACTION, MANNOSE GLYCOSIDASE INHIBITION
4ad5:A (VAL301) to (THR329) STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH GLUCOSE-1,3- DEOXYMANNOJIRIMYCIN AND ALPHA-1,2-MANNOBIOSE | HYDROLASE, ENDOMANNOSIDASE, GLYCOSIDE HYDROLASE, GH99, CAZY, ENZYME-CARBOHYDRATE INTERACTION, MANNOSE GLYCOSIDASE INHIBITION
3kle:J (LYS22) to (GLY51) CRYSTAL STRUCTURE OF AZT-RESISTANT HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO A DSDNA WITH A BOUND EXCISION PRODUCT, AZTPPPPA | AZT RESISTANCE MECHANISM, HIV-1, REVERSE TRANSCRIPTASE, RT, AZT, RESISTANCE MUTATIONS, P51/P66, NUCLEOSIDE INHIBITOR, NUCLEOTIDE EXCISION, THYMIDINE ANALOG MUTATIONS, AIDS, HIV, DNA POLYMERASE, NRTI, NRTI RESISTANCE, AZTPPPPA, AZTP4A, AZT ADENOSINE DINUCLEOSIDE TETRAPHOSPHATE, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3klf:E (HIS361) to (LYS390) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO A DSDNA WITH A BOUND EXCISION PRODUCT, AZTPPPPA | AZT RESISTANCE MECHANISM, HIV-1 REVERSE TRANSCRIPTASE, WILD-TYPE, AZT RESISTANCE MUTATIONS, P51/P66, NUCELEOSIDE INHIBITOR, THYMIDINE ANALOG MUTATIONS, AIDS, HIV, DNA POLYMERASE, NRTI, NRTI RESISTANCE, AZT, AZTPPPPA, AZTP4A, DINUCLEOSIDE TETRAPHOSPHATE, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEASE, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
4aef:A (PRO380) to (VAL412) THE CRYSTAL STRUCTURE OF THERMOSTABLE AMYLASE FROM THE PYROCOCCUS | HYDROLASE, THERMOSTABILITY, HIGH TEMPERATURE
3kls:X (GLU158) to (ASN192) STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH SSL7 | OB-FOLD, B-GRASP DOMAIN, FN3 DOMAIN, CLEAVAGE ON PAIR OF BASIC RESIDUES, COMPLEMENT ALTERNATE PATHWAY, COMPLEMENT PATHWAY, CYTOLYSIS, DISULFIDE BOND, GLYCOPROTEIN, IMMUNE RESPONSE, INFLAMMATORY RESPONSE, INNATE IMMUNITY, MEMBRANE ATTACK COMPLEX, SECRETED, IMMUNE SYSTEM
3kls:Y (GLU158) to (ASN192) STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH SSL7 | OB-FOLD, B-GRASP DOMAIN, FN3 DOMAIN, CLEAVAGE ON PAIR OF BASIC RESIDUES, COMPLEMENT ALTERNATE PATHWAY, COMPLEMENT PATHWAY, CYTOLYSIS, DISULFIDE BOND, GLYCOPROTEIN, IMMUNE RESPONSE, INFLAMMATORY RESPONSE, INNATE IMMUNITY, MEMBRANE ATTACK COMPLEX, SECRETED, IMMUNE SYSTEM
5d3d:A (GLU256) to (LYS291) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN 3 | SUPERANTIGENS, SUPERANTIGEN-LIKE PROTEINS, SSL, SSL3, TOLL-LIKE RECEPTOR 2, TLR2, IMMUNOLOGY, INFLAMMATION, INHIBITION, IMMUNE SYSTEM
5d3g:C (HIS361) to (LYS390) STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE BOUND TO A NOVEL 38-MER HAIRPIN TEMPLATE-PRIMER DNA APTAMER | REVERSE TRANSCRIPTASE, HIV, DNA APTAMER, 2-O-METHYLCYTIDINE, P66, P51, TRANSFERASE
5d3g:D (LYS22) to (LYS49) STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE BOUND TO A NOVEL 38-MER HAIRPIN TEMPLATE-PRIMER DNA APTAMER | REVERSE TRANSCRIPTASE, HIV, DNA APTAMER, 2-O-METHYLCYTIDINE, P66, P51, TRANSFERASE
1y7v:A (SER351) to (TRP381) X-RAY STRUCTURE OF HUMAN ACID-BETA-GLUCOSIDASE COVALENTLY BOUND TO CONDURITOL B EPOXIDE | GAUCHER DISEASE, GLUCOSIDASE, GLUCOCEREBROSIDASE, CEREZYME, HYDROLASE, GLYCOSIDASE, SPHINGOLIPID METABOLISM, GLYCOPROTEIN, LYSOSOME, MEMBRANE, DISEASE MUTATION, ALTERNATIVE INITIATION, ISRAEL STRUCTURAL PROTEOMICS CENTER, ISPC, STRUCTURAL GENOMICS
1y7v:B (SER351) to (TRP381) X-RAY STRUCTURE OF HUMAN ACID-BETA-GLUCOSIDASE COVALENTLY BOUND TO CONDURITOL B EPOXIDE | GAUCHER DISEASE, GLUCOSIDASE, GLUCOCEREBROSIDASE, CEREZYME, HYDROLASE, GLYCOSIDASE, SPHINGOLIPID METABOLISM, GLYCOPROTEIN, LYSOSOME, MEMBRANE, DISEASE MUTATION, ALTERNATIVE INITIATION, ISRAEL STRUCTURAL PROTEOMICS CENTER, ISPC, STRUCTURAL GENOMICS
4p6e:B (ASN67) to (ASP87) CRYSTAL STRUCTURE OF HUMAN CATHEPSIN S BOUND TO A NON-COVALENT INHIBITOR | CYSTEINE PROTEASE, CATHEPSIN S, INHIBITOR, NON-COVALENT
4p6g:A (ASN67) to (ASP87) CRYSTAL STRUCTURE OF HUMAN CATHEPSIN S BOUND TO A NON-COVALENT INHIBITOR. | CATHESPSIN S, NON-COVALENT INHIBITOR, CYSTEINE PROTEASE
4p6g:C (ASN67) to (ASP87) CRYSTAL STRUCTURE OF HUMAN CATHEPSIN S BOUND TO A NON-COVALENT INHIBITOR. | CATHESPSIN S, NON-COVALENT INHIBITOR, CYSTEINE PROTEASE
3kqh:A (THR449) to (VAL476) THREE CONFORMATIONAL SNAPSHOTS OF THE HEPATITIS C VIRUS NS3 HELICASE REVEAL A RATCHET TRANSLOCATION MECHANISM | HCV, NS3 PROTEIN, HELICASE, DNA-BINDING
1mto:F (ASN48) to (ARG72) CRYSTAL STRUCTURE OF A PHOSPHOFRUCTOKINASE MUTANT FROM BACILLUS STEAROTHERMOPHILUS BOUND WITH FRUCTOSE-6-PHOSPHATE | PHOSPHOFRUCTOKINASE, FRUCTOSE-6-PHOSPHATE, TRYPTOPHAN-SHIFT, TRANSFERASE
1yg8:F (PRO66) to (GLY93) THE STRUCTURE OF A V6A VARIANT OF CLPP. | ENDOPEPTIDASE CLP, CASEINOLYTIC PROTEASE, PROTEASE TI, HEAT SHOCK PROTEIN F21.5, HYDROLASE
5d9i:B (HIS201) to (LYS224) SV40 LARGE T ANTIGEN ORIGIN BINDING DOMAIN BOUND TO ARTIFICIAL DNA FORK | ORIGIN BINDING DOMAIN, REPLICATION, SV40, REPLICATION-DNA COMPLEX
1yjx:C (SER152) to (ALA184) CRYSTAL STRUCTURE OF HUMAN B TYPE PHOSPHOGLYCERATE MUTASE | ALPHA/BETA, ISOMERASE, HYDROLASE
1n06:B (ARG25) to (GLY67) CRYSTAL STRUCTURE OF SCHIZOSACCHAROMYCES POMBE RIBOFLAVIN KINASE REVEALS A NOVEL ATP AND RIBOFLAVIN BINDING FOLD | KINASE, PHOSPHORYL TRANSFERASES, FLAVIN COFACTORS, METAL BINDING
1n07:B (ARG25) to (GLY67) CRYSTAL STRUCTURE OF SCHIZOSACCHAROMYCES POMBE RIBOFLAVIN KINASE REVEALS A NOVEL ATP AND RIBOFLAVIN BINDING FOLD | KINASE, PHOSPHORYL TRANSFERASES, FLAVIN COFACTORS, METAL BINDING
5del:A (GLY475) to (GLY506) CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE BOUND WITH INHIBITOR DSM59 | ALPHA/BETA BARREL, MITOCHONDRIAL MEMBRANE, FMN, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
1n52:A (PRO222) to (HIS248) CAP BINDING COMPLEX | CBP80, CBP20, RNP DOMAIN, CAP BINDING PROTEIN, M7GPPPG, RNA BINDING PROTEIN
1yrx:A (GLY103) to (GLU122) STRUCTURE OF A NOVEL PHOTORECEPTOR: THE BLUF DOMAIN OF APPA FROM RHODOBACTER SPHAEROIDES | FERREDOXIN-LIKE FOLD, FLAVIN BINDING, PHOTORECEPTOR, TRANSCRIPTION
1ysj:A (VAL294) to (PRO322) CRYSTAL STRUCTURE OF BACILLUS SUBTILIS YXEP PROTEIN (APC1829), A DINUCLEAR METAL BINDING PEPTIDASE FROM M20 FAMILY | M20 FAMILY PEPTIDASE, DINUCLEAR METAL BINDING, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, HYDROLASE
5dm6:J (ALA41) to (ARG68) CRYSTAL STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS | PROTEIN SYNTHESIS, PEPTIDYLTRANSFERASE, RIBOZYME, RIBONUCLEOPROTEIN, RIBOSOME
4pnm:B (LEU954) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH NU1025. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
4pnn:B (PHE956) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 4HQN. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
4pnq:B (LEU954) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 5AIQ. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
4pnr:B (LEU954) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH TIQ-A. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
4pnt:B (LEU954) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 1,5-IQD. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
3aib:A (ALA435) to (ALA478) CRYSTAL STRUCTURE OF GLUCANSUCRASE | BETA-ALPHA-BARREL, TRANSFERASE
3aib:D (ASN436) to (ALA478) CRYSTAL STRUCTURE OF GLUCANSUCRASE | BETA-ALPHA-BARREL, TRANSFERASE
3aib:F (ASN436) to (ALA478) CRYSTAL STRUCTURE OF GLUCANSUCRASE | BETA-ALPHA-BARREL, TRANSFERASE
3aib:H (ASN436) to (ALA478) CRYSTAL STRUCTURE OF GLUCANSUCRASE | BETA-ALPHA-BARREL, TRANSFERASE
3aic:B (ALA435) to (ALA478) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
3aic:C (ASN436) to (ALA478) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
3aic:D (ASN436) to (ALA478) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
3aic:E (ASN436) to (ALA478) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
1z5w:A (PRO2) to (ASP56) CRYSTAL STRUCTURE OF GAMMA-TUBULIN BOUND TO GTP | COMPLEX WITH GTP, STRUCTURAL PROTEIN
4pqu:C (HIS361) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH RNA/DNA AND DATP | FINGERS, PALM, THUMB, CONNECTION, RNASE H, NUCLEOTIDYLTRANSFERASE, DNA-DIRECTED DNA POLYMERASE, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, HYDROLASE-DNA-RNA COMPLEX
3aie:B (ASN436) to (ALA478) CRYSTAL STRUCTURE OF GLUCANSUCRASE FROM STREPTOCOCCUS MUTANS | BETA-ALPHA-BARRELS, TRANSFERASE
1z6a:A (ILE646) to (ASN671) SULFOLOBUS SOLFATARICUS SWI2/SNF2 ATPASE CORE DOMAIN | HYDROLASE, RECOMBINATION, HYDROLASE-RECOMBINATION COMPLEX
1z7m:F (ASP155) to (VAL170) ATP PHOSPHORIBOSYL TRANSFERASE (HISZG ATP-PRTASE) FROM LACTOCOCCUS LACTIS | ATP-PRT, HISTIDINE BIOSYNTHESIS, TRANSFERASE, HISZG, ALLOSTERIC, EVOLUTION
1z7m:G (ASP155) to (VAL170) ATP PHOSPHORIBOSYL TRANSFERASE (HISZG ATP-PRTASE) FROM LACTOCOCCUS LACTIS | ATP-PRT, HISTIDINE BIOSYNTHESIS, TRANSFERASE, HISZG, ALLOSTERIC, EVOLUTION
3lg3:B (LYS202) to (THR234) 1.4A CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM YERSINIA PESTIS CO92 | ISOCITRATE LYASE, CONSERVED, CD, PROTEOMICS EVIDENCE (CYTOPLASMID OR PERIPLASMIC), DRUG TARGET FUNCTIONS, LYASE, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
5dql:C (GLY196) to (THR229) CRYSTAL STRUCTURE OF 2-VINYL GLYOXYLATE MODIFIED ISOCITRATE LYASE FROM MYCOBACTERIUM TUBERCULOSIS | LYASE-LYASE INHIBITOR COMPLEX
3lhs:A (PRO243) to (MET263) OPEN CONFORMATION OF HTSA COMPLEXED WITH STAPHYLOFERRIN A | SIDEROPHORE, IRON, RECEPTOR, LIPOPROTEIN, BINDING PROTEIN, TRANSPORT PROTEIN
3lkl:A (ARG49) to (GLY79) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF ANTI-SIGMA FACTOR ANTAGONIST STAS FROM RHODOBACTER SPHAEROIDES | MCSG, PSI, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, TRANSPORT PROTEIN
3lkl:B (ARG49) to (GLY79) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF ANTI-SIGMA FACTOR ANTAGONIST STAS FROM RHODOBACTER SPHAEROIDES | MCSG, PSI, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, TRANSPORT PROTEIN
3anv:A (LEU15) to (VAL44) CRYSTAL STRUCTURE OF D-SERINE DEHYDRATASE FROM CHICKEN KIDNEY (2,3-DAP COMPLEX) | PLP-DEPENDENT FOLD-TYPE III ENZYME, D-SERINE DEHYDRATASE, PLP BINDING, ZINC BINDING, LYASE
1ziv:A (PHE317) to (LEU336) CATALYTIC DOMAIN OF HUMAN CALPAIN-9 | CYSTEINE PROTEASE, PAPAIN, CALCIUM-DEPENDENT, THIOL PROTEASE, STRUCTURAL GENOMICS CONSORTIUM, SGC, HYDROLASE
5dxx:A (VAL72) to (LEU102) CRYSTAL STRUCTURE OF DBR2 | DBR2, OXIDOREDUCTASE
4q22:A (TYR371) to (GLU396) CRYSTAL STRUCTURE OF CHITINASE D FROM SERRATIA PROTEAMACULANS IN COMPLEX WITH N-ACETYL GLUCOSAMINE AT 1.93 ANGSTROM RESOLUTION | CHITINASE D, CHITINASE, GLYCOSIDE HYDROLASE, CHTIN, N-ACETYL GLUCOSAMINE, HYDROLASE
5dy3:A (VAL72) to (LEU102) CRYSTAL STRUCTURE OF DBR2 | DBR2, OXIDOREDUCTASE
1zqu:A (GLU147) to (VAL177) DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF ARTIFICIAL MOTHER LIQUOR | DNA-DIRECTED DNA POLYMERASE, DNA REPLICATION, DNA REPAIR, NUCLEOTIDYLTRANSFERASE
1zqy:A (GLU147) to (VAL177) DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF MGCL2 (50 MILLIMOLAR) | DNA-DIRECTED DNA POLYMERASE, DNA REPLICATION, DNA REPAIR, NUCLEOTIDYLTRANSFERASE
5e17:D (ARG1164) to (ARG1189) T. THERMOPHILUS TRANSCRIPTION INITIATION COMPLEX HAVING A RRR DISCRIMINATOR SEQUENCE AND A NONTEMPLATE-STRAND LENGTH CORRESPONDING TO TSS SELECTION AT POSITION 7 (RPO-GGG-7) | DNA, SINGLE-STRANDED, DNA-DIRECTED RNA POLYMERASES, GENE EXPRESSION REGULATION, BACTERIAL, PROMOTER REGIONS, PROTEIN CONFORMATION, SIGMA FACTOR, THERMUS THERMOPHILUS, TRANSCRIPTION INITIATION, START SITE SELECTION, PROMOTER ESCAPE, INITIAL TRANSCRIPT, ABORTIVE PRODUCT, SIGMA FINGER, TRANSCRIPTION-DNA-RNA COMPLEX
4awu:A (THR71) to (LEU101) CRYSTAL STRUCTURE OF THE OXIDIZED SHEWANELLA YELLOW ENZYME 1 (SYE1) M25L MUTANT IN COMPLEX WITH PARA-CHLOROPHENOL | OXIDOREDUCTASE
4axm:A (ASN66) to (GLU86) TRIAZINE CATHEPSIN INHIBITOR COMPLEX | HYDROLASE
3au2:A (GLY155) to (LEU185) DNA POLYMERASE X FROM THERMUS THERMOPHILUS HB8 COMPLEXED WITH CA-DGTP | RSGI, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, POLXC DOAMIN, PHP DOMAIN, DNA POLYMERASE, DRP LYASE, AP ENDONUCLEASE, DNA REPAIR, DNA BINDING, NUCLEOTIDE BINDING, TRANSFERASE
4b12:A (LEU277) to (GLU294) PLASMODIUM VIVAX N-MYRISTOYLTRANSFERASE WITH A BOUND BENZOFURAN INHIBITOR (COMPOUND 23) | TRANSFERASE, PLASMODIUM, MALARIA, DRUG DESIGN
4b13:A (LEU277) to (GLU294) PLASMODIUM VIVAX N-MYRISTOYLTRANSFERASE WITH A BOUND BENZOFURAN INHIBITOR (COMPOUND 25) | TRANSFERASE, MALARIA, DRUG DESIGN
4qa1:D (ASP233) to (ALA266) CRYSTAL STRUCTURE OF A188T HDAC8 IN COMPLEX WITH M344 | METALLOENZYME, HYDROLASE, HISTONE DEACETYLASE, ENZYME INHIBITOR COMPLEX, CORNELIA DE LANGE SYNDROME, ARGINASE/DEACETYLASE FOLD
4qa6:A (ASP233) to (GLY265) CRYSTAL STRUCTURE OF I243N/Y306F HDAC8 IN COMPLEX WITH A TETRAPEPTIDE SUBSTRATE | METALLOENZYME, HYDROLASE, HISTONE DEACETYLASE, ENZYME SUBSTRATE COMPLEX, CORNELIA DE LANGE SYNDROME, ARGINASE/DEACETYLASE FOLD
2a4z:A (ASP278) to (LEU307) CRYSTAL STRUCTURE OF HUMAN PI3KGAMMA COMPLEXED WITH AS604850 | PROTEIN-INHIBITOR COMPLEX, PI3KG, TRANSFERASE
4b3j:A (GLY111) to (ALA130) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FATTY ACID BETA-OXIDATION COMPLEX WITH COENZYMEA BOUND AT THE HYDRATASE AND THIOLASE ACTIVE SITES | OXIDOREDUCTASE-TRANSFERASE COMPLEX, TFE, TRIFUNCTIONAL ENZYME, HYDRATASE
5ebt:D (ILE1107) to (ILE1148) TANKYRASE 1 WITH PHTHALAZINONE 2 | TANKYRASE, PARP, CENTROSOME CLUSTERING, ONCOLOGY, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3b0h:B (ASN114) to (VAL140) ASSIMILATORY NITRITE REDUCTASE (NII4) FROM TOBBACO ROOT | SIROHEME, FE4S4 BINDING PROTEIN, OXIDOREDUCTASE
3b0m:A (ASN114) to (ILE140) M175K MUTANT OF ASSIMILATORY NITRITE REDUCTASE (NII3) FROM TOBBACO LEAF | SIROHEME, FE4S4 BINDING PROTEIN, OXIDOREDUCTASE
5eef:A (VAL289) to (ASP323) CRYSTAL STRUCTURE OF DANIO RERIO HISTONE DEACETYLASE 6 CATALYTIC DOMAIN 1 IN COMPLEX WITH TRICHOSTATIN A | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2aba:A (ALA71) to (ARG106) STRUCTURE OF REDUCED PETN REDUCTASE IN COMPLEX WITH PROGESTERONE | REDUCED FLAVOPROTEIN, ATOMIC RESOLUTION, PROGESTERONE, PETN, OXIDOREDUCTASE
2abh:A (LYS215) to (ASN243) PHOSPHATE-BINDING PROTEIN (RE-REFINED) | PHOSPHOTRANSFERASE, TRANSPORT
4qiw:B (THR491) to (LEU524) CRYSTAL STRUCTURE OF EURYARCHAEAL RNA POLYMERASE FROM THERMOCOCCUS KODAKARENSIS | TRANSCRIPTION, DNA-DIRECTED RNA POLYMERASE
4qiw:H (LEU14) to (LYS44) CRYSTAL STRUCTURE OF EURYARCHAEAL RNA POLYMERASE FROM THERMOCOCCUS KODAKARENSIS | TRANSCRIPTION, DNA-DIRECTED RNA POLYMERASE
4qiw:S (LEU14) to (LYS44) CRYSTAL STRUCTURE OF EURYARCHAEAL RNA POLYMERASE FROM THERMOCOCCUS KODAKARENSIS | TRANSCRIPTION, DNA-DIRECTED RNA POLYMERASE
4qmg:A (GLY225) to (GLU266) THE STRUCTURE OF MTDH-SND1 COMPLEX REVEALS NOVEL CANCER-PROMOTING INTERACTIONS | SN DOMAINS, OLIGONUCLEOTIDE/OLIGOSACCHARIDE BINDING-FOLD (OB-FOLD), DNA/RNA-BINDING, MIRNA-MEDIATED SILENCING, NUCLEASE, BREAST CANCER, TUMORIGENESIS, SND1, MTDH, TRANSCRIPTION
3b8u:A (ALA4) to (VAL33) CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221A | ALPHA/BETA BARREL, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, ISOMERASE, PEPTIDOGLYCAN SYNTHESIS, PYRIDOXAL PHOSPHATE
5eno:C (ARG239) to (LEU270) MBX2319 BOUND STRUCTURE OF BACTERIAL EFFLUX PUMP. | EFFLUX PUMP, TRANSPORT PROTEIN
5enq:A (ARG239) to (LEU270) MBX3132 BOUND STRUCTURE OF BACTERIAL EFFLUX PUMP. | EFFLUX PUMP, TRANSPORT PROTEIN
5enq:B (ARG239) to (LEU270) MBX3132 BOUND STRUCTURE OF BACTERIAL EFFLUX PUMP. | EFFLUX PUMP, TRANSPORT PROTEIN
5enp:C (ALA236) to (LEU270) MBX2931 BOUND STRUCTURE OF BACTERIAL EFFLUX PUMP. | EFFLUX PUMP, TRANSPORT PROTEIN
5enr:B (ARG239) to (LEU270) MBX3135 BOUND STRUCTURE OF BACTERIAL EFFLUX PUMP. | EFFLUX PUMP, TRANSPORT PROTEIN
5ens:C (ARG239) to (LEU270) RHODAMINE BOUND STRUCTURE OF BACTERIAL EFFLUX PUMP. | EFFLUX PUMP, TRANSPORT PROTEIN
3bez:D (GLY65) to (LEU120) CRYSTAL STRUCTURE OF ESCHERICHIA COLI SIGNAL PEPTIDE PEPTIDASE (SPPA), SEMET CRYSTALS | PROTEASE, BACTERIAL, HYDROLASE, INNER MEMBRANE, MEMBRANE, TRANSMEMBRANE
3mof:A (MET173) to (ILE190) THE STRUCTURE OF RAT CYTOSOLIC PEPCK MUTANT A467G IN COMPLEX WITH OXALATE AND GTP | KINASE, GLUCONEOGENESIS, LYASE
3bgr:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF K103N/Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH TMC278 (RILPIVIRINE), A NON-NUCLEOSIDE RT INHIBITOR | P51/P66, HETERO DIMER, NNRTI, NONNUCLEOSIDE INHIBITOR, AIDS, HIV, R278474, RILPIVIRINE, DIARYLPYRIMIDINE, DAPY, DNA RECOMBINATION, RNA-DIRECTED DNA POLYMERASE, DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MULTIFUNCTIONAL ENZYME, TRANSFERASE, K103N, Y181C
5evj:A (ASP199) to (GLU249) X-RAY CRYSTAL STRUCTURE OF CRARSM, AN ARSENIC (III) S- ADENOSYLMETHIONINE METHYLTRANSFERASE FROM CHLAMYDOMONAS REINHARDTII | METHYLTRANSFERASE, ARSENIC METHYLTRANSFERASE, TRANSFERASE
4bpv:D (GLY190) to (ASP210) MOUSE CATHEPSIN S WITH COVALENT LIGAND | HYDROLASE, CYSTEINE PROTEASE, COVALENT LIGAND
4bqv:C (GLY190) to (ASP210) MOUSE CATHEPSIN S WITH COVALENT LIGAND | HYDROLASE, CYSTEINE PROTEASE
3mz6:A (ASP233) to (ALA266) CRYSTAL STRUCTURE OF D101L FE2+ HDAC8 COMPLEXED WITH M344 | HYDROLASE, METALLOHYDROLASE, ARGINASE-FOLD, FERROUS
4bs6:B (GLY190) to (ASP210) MOUSE CATHEPSIN S WITH COVALENT LIGAND | HYDROLASE, CYSTEINE PROTEASE, COVALENT LIGAND
4bud:A (GLY952) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 2-(4- TERT-BUTYLPHENYL)-1,4-DIHYDROQUINAZOLIN-4-ONE | TRANSFERASE, DIPHTHERIA TOXIN LIKE FOLD, ADP-RIBOSYLATION, INHIBITOR
4r5p:A (HIS361) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) WITH DNA AND A NUCLEOSIDE TRIPHOSPHATE MIMIC ALPHA-CARBOXY NUCLEOSIDE PHOSPHONATE INHIBITOR | ZIDOVUDINE, RT-DNA COMPLEX, AIDS, DNA-DIRECTED DNA POLYMERASE, RN LIPOPROTEIN, HIV, METAL-BINDING, ALPHA-CNP, RIBONUCLEASE H, RNASE H, A-CNP, MULTIFUNCTIONAL ENZYME, NUCLEOTIDYLTRANSFERASE, RNA-DIRECTED POLYMERASE, TRANSFERASE, HYDROLASE-DNA-INHIBITOR COMPLEX
4r5p:C (HIS361) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) WITH DNA AND A NUCLEOSIDE TRIPHOSPHATE MIMIC ALPHA-CARBOXY NUCLEOSIDE PHOSPHONATE INHIBITOR | ZIDOVUDINE, RT-DNA COMPLEX, AIDS, DNA-DIRECTED DNA POLYMERASE, RN LIPOPROTEIN, HIV, METAL-BINDING, ALPHA-CNP, RIBONUCLEASE H, RNASE H, A-CNP, MULTIFUNCTIONAL ENZYME, NUCLEOTIDYLTRANSFERASE, RNA-DIRECTED POLYMERASE, TRANSFERASE, HYDROLASE-DNA-INHIBITOR COMPLEX
4r5w:A (ILE895) to (GLY922) HUMAN ARTD1 (PARP1) - CATALYTIC DOMAIN IN COMPLEX WITH INHIBITOR XAV939 | ADP-RIBOSYLATION, DNA REPAIR, ADP-RIBOSYL TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4r5w:B (ILE895) to (GLY922) HUMAN ARTD1 (PARP1) - CATALYTIC DOMAIN IN COMPLEX WITH INHIBITOR XAV939 | ADP-RIBOSYLATION, DNA REPAIR, ADP-RIBOSYL TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4r6e:C (ILE895) to (GLY922) HUMAN ARTD1 (PARP1) - CATALYTIC DOMAIN IN COMPLEX WITH INHIBITOR NIRAPARIB | ADP-RIBOSYLATION, DNA REPAIR, ADP-RIBOSYL TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4r6e:D (ILE895) to (GLY922) HUMAN ARTD1 (PARP1) - CATALYTIC DOMAIN IN COMPLEX WITH INHIBITOR NIRAPARIB | ADP-RIBOSYLATION, DNA REPAIR, ADP-RIBOSYL TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3c6o:B (MET115) to (SER139) SMALL MOLECULE AGONISTS AND ANTAGONISTS OF F-BOX PROTEIN-SUBSTRATE INTERACTIONS IN AUXIN PERCEPTION AND SIGNALING | AUXIN, UBIQUITIN LIGASE, F-BOX, SMALL MOLECULE, CHEMICAL BIOLOGY, PLANT PHYSIOLOGY, AUXIN SIGNALING PATHWAY, CHROMOSOME PARTITION, CYTOSKELETON, DEVELOPMENTAL PROTEIN, ETHYLENE SIGNALING PATHWAY, NUCLEUS, UBL CONJUGATION PATHWAY, CELL CYCLE, LEUCINE-RICH REPEAT, PLANT DEFENSE, SIGNALING PROTEIN
5fj8:E (PRO86) to (VAL111) CRYO-EM STRUCTURE OF YEAST RNA POLYMERASE III ELONGATION COMPLEX AT 3.9 A | RNA POLYMERASE III, POL III, TRANSCRIPTION, RNA POLYMERASE
4rfb:B (GLU157) to (MET193) 1.93 ANGSTROM CRYSTAL STRUCTURE OF SUPERANTIGEN-LIKE PROTEIN FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH SIALYL-LEWIS X. | SIALYL-LEWIS X, SUPERANTIGEN-LIKE PROTEIN, CSGID, STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, TOXIN
4rgt:A (GLU157) to (MET193) 2.0 ANGSTROM CRYSTAL STRUCTURE OF SUPERANTIGEN-LIKE PROTEIN FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH 3-N-ACETYLNEURAMINYL-N- ACETYLLACTOSAMINE. | 3-N-ACETYLNEURAMINYL-N-ACETYLLACTOSAMINE, SUPERANTIGEN-LIKE PROTEIN, CSGID, STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, TOXIN
4rgt:B (GLU157) to (GLU194) 2.0 ANGSTROM CRYSTAL STRUCTURE OF SUPERANTIGEN-LIKE PROTEIN FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH 3-N-ACETYLNEURAMINYL-N- ACETYLLACTOSAMINE. | 3-N-ACETYLNEURAMINYL-N-ACETYLLACTOSAMINE, SUPERANTIGEN-LIKE PROTEIN, CSGID, STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, TOXIN
4c5j:C (GLY11) to (LEU38) STRUCTURE OF THE PYRIDOXAL KINASE FROM STAPHYLOCOCCUS AUREUS | TRANSFERASE, RIBOKINASE
5foe:B (PRO114) to (GLN135) CRYSTAL STRUCTURE OF THE C. ELEGANS PROTEIN O- FUCOSYLTRANSFERASE 2 (CEPOFUT2) DOUBLE MUTANT (R298K-R299K) IN COMPLEX WITH GDP AND THE HUMAN TSR1 FROM THROMBOSPONDIN 1 | TRANSFERASE, POFUT2, WATERS, FUSION PROTEIN, AFM, ITC, GLYCOSYLTRANSFERASE, SITE-DIRECTED MUTAGENESIS, MOLECULAR DYNAMICS, TSR1
4cae:A (LEU277) to (GLU294) PLASMODIUM VIVAX N-MYRISTOYLTRANSFERASE IN COMPLEX WITH A BENZOTHIOPHENE INHIBITOR (COMPOUND 20B) | TRANSFERASE, MYRISTOYLATION, MALARIA, INHIBITOR, BENZOTHIOPHENE
4cae:B (LEU277) to (GLU294) PLASMODIUM VIVAX N-MYRISTOYLTRANSFERASE IN COMPLEX WITH A BENZOTHIOPHENE INHIBITOR (COMPOUND 20B) | TRANSFERASE, MYRISTOYLATION, MALARIA, INHIBITOR, BENZOTHIOPHENE
4ccv:A (SER123) to (ARG161) CRYSTAL STRUCTURE OF HISTIDINE-RICH GLYCOPROTEIN N2 DOMAIN REVEALS REDOX ACTIVITY AT AN INTERDOMAIN DISULFIDE BRIDGE: IMPLICATIONS FOR THE REGULATION OF ANGIOGENESIS | BLOOD CLOTTING, COAGULATION, CYSTATIN, S-GLUTATHIONYLATION
4rnu:A (ALA184) to (LEU214) G303 CIRCULAR PERMUTATION OF OLD YELLOW ENZYME | CIRCULAR PERMUTATION, CATALYSIS, OLD YELLOW ENZYME, FLAVIN COFACTOR, OXIDOREDUCTASE
4rnu:B (ALA184) to (LEU214) G303 CIRCULAR PERMUTATION OF OLD YELLOW ENZYME | CIRCULAR PERMUTATION, CATALYSIS, OLD YELLOW ENZYME, FLAVIN COFACTOR, OXIDOREDUCTASE
4rnu:D (ALA184) to (LEU214) G303 CIRCULAR PERMUTATION OF OLD YELLOW ENZYME | CIRCULAR PERMUTATION, CATALYSIS, OLD YELLOW ENZYME, FLAVIN COFACTOR, OXIDOREDUCTASE
5fuu:E (CYS331) to (PHE361) ECTODOMAIN OF CLEAVED WILD TYPE JR-FL ENVDCT TRIMER IN COMPLEX WITH PGT151 FAB | VIRAL PROTEIN, HIV-1, ENV, PGT151, BROADLY NEUTRALIZING ANTIBODY
3cqz:B (LYS404) to (LYS451) CRYSTAL STRUCTURE OF 10 SUBUNIT RNA POLYMERASE II IN COMPLEX WITH THE INHIBITOR ALPHA-AMANITIN | TRANSCRIPTION-TOXIN COMPLEX, ALPHA AMANITIN, TOXIN, INHIBITOR, POLYMERASE, TRANSFERASE, DNA BINDING, ZINC-FINGER, PHOSPHOPROTEIN, TRANSCRIPTION
4rw4:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (K103N,Y181C) VARIANT IN COMPLEX WITH (E)-3-(3-CHLORO-5-(4-CHLORO-2-(2-(2,4-DIOXO-3,4- DIHYDROPYRIMIDIN-1(2H)-YL)ETHOXY)PHENOXY)PHENYL)ACRYLONITRILE (JLJ494), A NON-NUCLEOSIDE INHIBITOR | POLYMERASE, TRANSFERASE, HYDROLASE, RNASEH, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3o13:A (GLU157) to (MSE192) CRYSTAL STRUCTURE OF A SUPERANTIGEN-LIKE PROTEIN (SAV0433) FROM STAPHYLOCOCCUS AUREUS MU50 AT 2.05 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, TOXIN
4rw6:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (Y181C) VARIANT IN COMPLEX WITH (E)-3-(3-CHLORO-5-(4-CHLORO-2-(2-(2,4-DIOXO-3,4- DIHYDROPYRIMIDIN-1(2H)-YL)ETHOXY)PHENOXY)PHENYL)ACRYLONITRILE (JLJ494), A NON-NUCLEOSIDE INHIBITOR | POLYMERASE, TRANSFERASE, HYDROLASE, RNASEH, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4rw7:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (K103N, Y181C) VARIANT IN COMPLEX WITH (E)-3-(3-CHLORO-5-(2-(2-(2,4-DIOXO-3,4- DIHYDROPYRIMIDIN-1(2H)-YL)ETHOXY)PHENOXY)PHENYL)ACRYLONITRILE (JLJ532), A NON-NUCLEOSIDE INHIBITOR | POLYMERASE, TRANSFERASE, RNASEH, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4rw8:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH (E)- 3-(3-CHLORO-5-(2-(2-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)ETHOXY) PHENOXY)PHENYL)ACRYLONITRILE (JLJ532), A NON-NUCLEOSIDE INHIBITOR' | POLYMERASE, TRANSFERASE, RNASEH, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4cnj:A (PHE232) to (ASP255) L-AMINOACETONE OXIDASE FROM STREPTOCOCCUS OLIGOFERMENTANS BELONGS TO A NEW 3-DOMAIN FAMILY OF BACTERIAL FLAVOPROTEINS | OXIDOREDUCTASE, FLAVOPROTEINS
4cnj:B (PHE232) to (ASP255) L-AMINOACETONE OXIDASE FROM STREPTOCOCCUS OLIGOFERMENTANS BELONGS TO A NEW 3-DOMAIN FAMILY OF BACTERIAL FLAVOPROTEINS | OXIDOREDUCTASE, FLAVOPROTEINS
4cnk:A (GLY233) to (LEU257) L-AMINOACETONE OXIDASE FROM STREPTOCOCCUS OLIGOFERMENTANS BELONGS TO A NEW 3-DOMAIN FAMILY OF BACTERIAL FLAVOPROTEINS | OXIDOREDUCTASE, FLAVOPROTEINS
4tjy:B (LEU954) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH ABT-888. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP)
4tjy:C (LEU954) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH ABT-888. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP)
4tk0:B (LEU954) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH DPQ. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
4tk5:B (LEU954) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH EB47. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
4tkg:C (LEU954) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH AZD2281. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
3oaw:A (ASP278) to (LEU307) 4-METHYLPTERIDINEONES AS ORALLY ACTIVE AND SELECTIVE PI3K/MTOR DUAL INHIBITORS | PHOSPHOINOSITIDE KINASE, TRANSFERASE-TRANSFERASE, INHIBITION, INHIBITOR COMPLEX., TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4cuj:D (ASP54) to (CYS76) STRUCTURE OF SALMONELLA D-LACTATE DEHYDROGENASE | OXIDOREDUCTASE, D-2-HYDROXYACID DEHYDROGENASES, LDH, PYRUVATE
4tmb:B (VAL85) to (LEU115) CRYSTAL STRUCTURE OF OLD YELLOW ENZYME FROM CANDIDA MACEDONIENSIS AKU4588 | TIM BARREL MOTIF, DEHYDROGENASE, FLAVOPROTEIN
3daq:A (ASN110) to (PRO138) CRYSTAL STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE FROM METHICILLIN- RESISTANT STAPHYLOCOCCUS AUREUS | DIHYDRODIPICOLINATE SYNTHASE, LYSINE BIOSYNTHESIS, AMINO-ACID BIOSYNTHESIS, DIAMINOPIMELATE BIOSYNTHESIS, LYASE, SCHIFF BASE
3daq:B (ASN110) to (PRO138) CRYSTAL STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE FROM METHICILLIN- RESISTANT STAPHYLOCOCCUS AUREUS | DIHYDRODIPICOLINATE SYNTHASE, LYSINE BIOSYNTHESIS, AMINO-ACID BIOSYNTHESIS, DIAMINOPIMELATE BIOSYNTHESIS, LYASE, SCHIFF BASE
3daq:C (ASN110) to (PRO138) CRYSTAL STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE FROM METHICILLIN- RESISTANT STAPHYLOCOCCUS AUREUS | DIHYDRODIPICOLINATE SYNTHASE, LYSINE BIOSYNTHESIS, AMINO-ACID BIOSYNTHESIS, DIAMINOPIMELATE BIOSYNTHESIS, LYASE, SCHIFF BASE
3daq:D (ASN110) to (PRO138) CRYSTAL STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE FROM METHICILLIN- RESISTANT STAPHYLOCOCCUS AUREUS | DIHYDRODIPICOLINATE SYNTHASE, LYSINE BIOSYNTHESIS, AMINO-ACID BIOSYNTHESIS, DIAMINOPIMELATE BIOSYNTHESIS, LYASE, SCHIFF BASE
3ogl:L (MET122) to (LEU145) STRUCTURE OF COI1-ASK1 IN COMPLEX WITH JA-ISOLEUCINE AND THE JAZ1 DEGRON | LEUCINE-RICH REPEATS, UBIQUITIN LIGASE, SCF, PROTEIN BINDING
3ogl:L (GLY363) to (VAL385) STRUCTURE OF COI1-ASK1 IN COMPLEX WITH JA-ISOLEUCINE AND THE JAZ1 DEGRON | LEUCINE-RICH REPEATS, UBIQUITIN LIGASE, SCF, PROTEIN BINDING
3di0:B (ASN110) to (PRO138) CRYSTAL STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE FROM STAPHYLOCOCCUS AUREUS | DIHYDRODIPICOLINATE SYNTHASE, LYSINE BIOSYNTHESIS, FEEB-BACK INHIBITION, PING-PONG MECHANISM, AMINO-ACID BIOSYNTHESIS, DIAMINOPIMELATE BIOSYNTHESIS, LYASE, SCHIFF BASE
3oiz:A (ARG439) to (GLY469) CRYSTAL STRUCTURE OF ANTISIGMA-FACTOR ANTAGONIST, STAS DOMAIN FROM RHODOBACTER SPHAEROIDES | PSI-2, MIDWEST CENTER FOR STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, MCSG, STAS DOMAIN, MEMBRANE PROTEIN
5gsy:K (GLN11) to (LEU32) KINESIN-8 MOTOR, KIF19A, IN THE NUCLEOTIDE-FREE STATE COMPLEXED WITH GDP-TAXOL MICROTUBULE | KINESIN-8, KIF19A, GDP-TAXOL-MICROTUBULE, PLUS-END DIRECTED MOTOR, MICROTUBULE DEPOLYMERIZATION, MOTOR PROTEIN
5gsz:A (GLN11) to (LEU32) CRYSTAL STRUCTURE OF THE KIF19A MOTOR DOMAIN COMPLEXED WITH MG-ADP | KINESIN, MOTOR DOMAIN, MG-ADP, MOTOR PROTEIN
4d5e:A (ALA2) to (GLY24) CRYSTAL STRUCTURE OF RECOMBINANT WILDTYPE CDH | HYDROLASE, C-C BOND CLEAVAGE, C-C BOND FORMATION
4d5e:B (ALA2) to (GLY24) CRYSTAL STRUCTURE OF RECOMBINANT WILDTYPE CDH | HYDROLASE, C-C BOND CLEAVAGE, C-C BOND FORMATION
3drr:B (LYS22) to (GLY51) HIV REVERSE TRANSCRIPTASE Y181C MUTANT IN COMPLEX WITH INHIBITOR R8E | HIV-1 REVERSE TRANSCRIPTASE, NON-NUCLEOSIDE INHIBITION, NUCLEOTIDYLTRASFERASE, HYDROLASE, TRANSFERASE
3dt2:A (MET173) to (ILE190) THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH OXALATE AND GTP | KINASE, GLUCONEOGENESIS, LYASE, DECARBOXYLASE, GTP-BINDING, NUCLEOTIDE-BINDING
3dt4:A (MET173) to (ILE190) THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH OXALATE AND GTP | KINASE, GLUCONEOGENESIS, LYASE, DECARBOXYLASE, GTP-BINDING, NUCLEOTIDE-BINDING
3dt4:C (MET173) to (ILE190) THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH OXALATE AND GTP | KINASE, GLUCONEOGENESIS, LYASE, DECARBOXYLASE, GTP-BINDING, NUCLEOTIDE-BINDING
3dt7:A (MET173) to (ILE190) THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH BETA- SULFOPYRUVATE AND GTP | KINASE, GLUCONEOGENESIS, LYASE, DECARBOXYLASE, GTP-BINDING, NUCLEOTIDE-BINDING
3p0x:A (GLY190) to (THR223) CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BRUCELLA MELITENSIS, BOUND TO MAGNESIUM ISOCITRATE | SSGCID, LYASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3p0x:B (GLY190) to (THR223) CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BRUCELLA MELITENSIS, BOUND TO MAGNESIUM ISOCITRATE | SSGCID, LYASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3p0x:C (GLY190) to (THR223) CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BRUCELLA MELITENSIS, BOUND TO MAGNESIUM ISOCITRATE | SSGCID, LYASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3p0x:D (GLY190) to (THR223) CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BRUCELLA MELITENSIS, BOUND TO MAGNESIUM ISOCITRATE | SSGCID, LYASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3p16:C (GLY137) to (ASP158) CRYSTAL STRUCTURE OF DNA POLYMERASE III SLIDING CLAMP | DNA POLYMERASE III SLIDING CLAMP, TRANSFERASE
4dl4:A (ALA330) to (GLN365) HUMAN DNA POLYMERASE ETA INSERTING DCMPNPP OPPOSITE THE 3'G OF CISPLATIN CROSSLINKED GS (PT-GG1). | CISPLATIN, CHEMORESISTENCE, TRANSLESION SYNTHESIS, HUMAN DNA POLYMERSE ETA, KINETICS, MOLECULAR SPLINT, INHIBITION, DNA DISTORSION, SECOND TLS POLYMERASE, NUCLEOTIDYL TRANSFER REACTION, PCNA, TRANSFERASE-DNA-INHIBITOR COMPLEX
4dl6:A (ALA330) to (GLN365) HUMAN DNA POLYMERASE ETA EXTENDING PRIMER IMMEDIATELY AFTER CISPLATIN CROSSLINK (PT-GG3). | CISPLATIN, CHEMORESISTENCE, TRANSLESION SYNTHESIS, HUMAN DNA POLYMERSE ETA, KINETICS, MOLECULAR SPLINT, INHIBITION, DNA DISTORSION, SECOND TLS POLYMERASE, NUCLEOTIDYL TRANSFER REACTION, PCNA, TRANSFERASE-DNA-INHIBITOR COMPLEX
3p45:G (ALA132) to (GLN161) CRYSTAL STRUCTURE OF APO-CASPASE-6 AT PHYSIOLOGICAL PH | PROTEASE, HUNTINGTON'S DISEASE, MATURE APO-CASPASE-6, PHYSIOLOGICAL PH, COMPETITIVE INHIBITION, HYDROLASE
3p62:A (ALA71) to (ARG106) WILD-TYPE PENTAERYTHRITOL TETRANITRATE REDUCTASE CONTAINING A C- TERMINAL 8-HISTIDINE TAG | OLD YELLOW ENZYME FAMILY, ALPHA,BETA BARREL, ALKENE REDUCTION, OXIDOREDUCTASE
4u8v:B (ARG239) to (LEU270) COUPLING OF REMOTE ALTERNATING-ACCESS TRANSPORT MECHANISMS FOR PROTONS AND SUBSTRATES IN THE MULTIDRUG EFFLUX PUMP ACRB | MEMBRANE PROTEIN, TRANSPORT PROTEIN, DARPIN, MULTIDRUG EFFLUX PROTEIN
3p74:A (ALA71) to (LEU101) H181N MUTANT OF PENTAERYTHRITOL TETRANITRATE REDUCTASE CONTAINING A C- TERMINAL HIS8-TAG | OLD YELLOW ENZYME FAMILY, ALPHA/BETA BARREL, OXIDOREDUCTASE
3p74:A (THR147) to (ASN181) H181N MUTANT OF PENTAERYTHRITOL TETRANITRATE REDUCTASE CONTAINING A C- TERMINAL HIS8-TAG | OLD YELLOW ENZYME FAMILY, ALPHA/BETA BARREL, OXIDOREDUCTASE
3p80:A (ALA71) to (ARG106) PENTAERYTHRITOL TETRANITRATE REDUCTASE CO-CRYSTAL STRUCTURE CONTAINING BOUND (E)-1-(3'-HYDROXYPHENYL)-2-NITROETHENE | OLD YELLOW ENZYME FAMILY, ALPHA, BETA BARREL, OXIDOREDUCTASE
3p81:A (ALA71) to (ARG106) PENTAERYTHRITOL TETRANITRATE REDUCTASE CO-CRYSTAL STRUCTURE CONTAINING A BOUND (E)-1-(4'-HYDROXYPHENYL)-2-NITROETHENE MOLECULE | OLD YELLOW ENZYME FAMILY, ALPHA, BETA BARREL, OXIDOREDUCTASE
3p8i:A (ALA71) to (ARG106) Y351F MUTANT OF PENTAERYTHRITOL TETRANITRATE REDUCTASE CONTAINING A BOUND ACETATE MOLECULE | OLD YELLOW ENZYME FAMILY, ALPHA, BETA BARREL, OXIDOREDUCTASE
3p8j:A (ALA71) to (ARG106) Y351S MUTANT OF PENTAERYTHRITOL TETRANITRATE REDUCTASE CONTAINING A BOUND ACETATE MOLECULE | OLD YELLOW ENZYME FAMILY, ALPHA, BETA BARREL, OXIDOREDUCTASE
5hwm:A (ILE115) to (ASN141) CRYSTAL STRUCTURE OF KETO-DEOXY-D-GALACTARATE DEHYDRATASE COMPLEXED WITH 2-OXOADIPIC ACID | DECARBOXYLATING, DEHYDRATASE, TIM-BARREL, LYASE
3pfe:A (ASN374) to (GLY409) CRYSTAL STRUCTURE OF A M20A METALLO PEPTIDASE (DAPE, LPG0809) FROM LEGIONELLA PNEUMOPHILA SUBSP. PNEUMOPHILA STR. PHILADELPHIA 1 AT 1.50 A RESOLUTION | METAL BINDING, MEROPS M20 FAMILIY, PHOSPHORYLASE/HYDROLASE-LIKE FOLD, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, HYDROLASE
3phf:O (GLY311) to (GLY342) CRYSTAL STRUCTURE OF THE EPSTEIN-BARR VIRUS GH AND GL COMPLEX | VIRUS ENTRY, MEMBRANE FUSION, GLYCOPROTEIN, VIRAL PROTEIN
3phf:1 (GLY311) to (GLY342) CRYSTAL STRUCTURE OF THE EPSTEIN-BARR VIRUS GH AND GL COMPLEX | VIRUS ENTRY, MEMBRANE FUSION, GLYCOPROTEIN, VIRAL PROTEIN
4uhx:A (GLY1043) to (GLY1074) HUMAN ALDEHYDE OXIDASE IN COMPLEX WITH PHTHALAZINE AND THIORIDAZINE | OXIDOREDUCTASE, ALDEHYDE OXIDASE, DRUG METABOLISM, MOLYBDENUM ENZYMES, XANTHINE OXIDASE, PHTHALAZINE, THIORIDAZINE
5i33:A (VAL82) to (SER110) UNLIGATED ADENYLOSUCCINATE SYNTHETASE FROM CRYPTOCOCCUS NEOFORMANS | DIMER, ADENYLOSUCCINATE SYNTHETASE, PURINE METABOLISM, LIGASE
3phz:B (LEU149) to (TYR173) CRYSTAL STRUCTURE ANALYSIS OF POLYPORUS SQUAMOSUS LECTIN BOUND TO HUMAN-TYPE INFLUENZA-BINDING EPITOPE NEU5ACA2-6GALB1-4GLCNAC | BETA TREFOIL, SACCHARIDE BINDING LECTIN, 2,6-SIALYL-LACTOSAMINE, SUGAR BINDING PROTEIN
5i3u:A (HIS361) to (LYS390) STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE N-SITE COMPLEX; CATALYTIC INCORPORATION OF AZTMP TO A DNA APTAMER IN CRYSTAL | RT, DNA APTAMER, FOSCAVIR, N SITE COMPLEX, PYROPHOSPHATE, PYROPHOSPHOROLYSIS, PHOSPHONOFORMIC ACID, PFA, 2-O-METHYLCYTIDINE, P51, P66, TRANSFERASE, TRANSFERASE-DNA COMPLEX
5i3u:C (HIS361) to (LYS390) STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE N-SITE COMPLEX; CATALYTIC INCORPORATION OF AZTMP TO A DNA APTAMER IN CRYSTAL | RT, DNA APTAMER, FOSCAVIR, N SITE COMPLEX, PYROPHOSPHATE, PYROPHOSPHOROLYSIS, PHOSPHONOFORMIC ACID, PFA, 2-O-METHYLCYTIDINE, P51, P66, TRANSFERASE, TRANSFERASE-DNA COMPLEX
5i4m:B (ILE335) to (ASP364) CRYSTAL STRUCTURE OF AMIDASE, HYDANTOINASE/CARBAMOYLASE FAMILY FROM BURKHOLDERIA VIETNAMIENSIS | SSGCID, AMIDASE, HYDANTOINASE/CARBAMOYLASE FAMILY, BURKHOLDERIA THAILANDENSIS, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, HYDROLASE
4dxf:B (GLU130) to (SER157) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN 4 | OLIGONUCLEOTIDE/OLIGOSACCHARIDE BINDING FOLD, BETA GRASP FOLD, SUPERANTIGEN FOLD, CARBOHYDRATE BINDING, SUGAR BINDING PROTEIN
4up2:B (GLY201) to (SER228) CRYSTAL STRUCTURE OF ESCHERICHIA COLI TRYPTOPHANASE PURIFIED FROM ALKALINE STRESSED BACTERIAL CULTURE. | LYASE, ALKALINE STRESS, PROTEIN PURIFICATION
5i84:A (LYS239) to (THR268) STRUCTURE OF THE XANTHOMONAS CITRI PHOSPHATE-BINDING PROTEIN PHOX | ABC TRANSPORTER, PERIPLASMIC-BINDING PROTEIN, PHOSPHATE-BINDING PROTEIN, PHOX, TRANSPORT PROTEIN
5i84:B (LYS239) to (THR268) STRUCTURE OF THE XANTHOMONAS CITRI PHOSPHATE-BINDING PROTEIN PHOX | ABC TRANSPORTER, PERIPLASMIC-BINDING PROTEIN, PHOSPHATE-BINDING PROTEIN, PHOX, TRANSPORT PROTEIN
5i84:D (LYS239) to (THR268) STRUCTURE OF THE XANTHOMONAS CITRI PHOSPHATE-BINDING PROTEIN PHOX | ABC TRANSPORTER, PERIPLASMIC-BINDING PROTEIN, PHOSPHATE-BINDING PROTEIN, PHOX, TRANSPORT PROTEIN
5i84:F (LYS239) to (THR268) STRUCTURE OF THE XANTHOMONAS CITRI PHOSPHATE-BINDING PROTEIN PHOX | ABC TRANSPORTER, PERIPLASMIC-BINDING PROTEIN, PHOSPHATE-BINDING PROTEIN, PHOX, TRANSPORT PROTEIN
5idl:A (CYS105) to (PHE134) CRYSTAL STRUCTURE OF THE GERMLINE-TARGETING HIV-1 GP120 ENGINEERED OUTER DOMAIN, EOD-GT8 | HIV ENV, GERMLINE-TARGETING IMMUNOGEN, VIRAL PROTEIN
5ies:C (CYS105) to (PHE134) CRYSTAL STRUCTURE OF VRC01C-HUGL2 FAB FROM AN HIV-1 NAIVE DONOR IN COMPLEX WITH WITH A GERMLINE-TARGETING GP120 ENGINEERED OUTER DOMAIN EOD-GT8 AT 2.16 A | HIV-1 GP120, ENGINEERED OUTER DOMAIN (EOD), GERMLINE TARGETING, CD4 BINDING SITE, VRC01-CLASS NAIVE HUMAN GERMLINE ANTIBODY, IMMUNE SYSTEM, VIRAL-PROTEIN COMPLEX, IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX, IMMUNE SYSTEM- VIRAL PROTEIN COMPLEX
5if0:I (CYS105) to (PHE134) CRYSTAL STRUCTURE OF VRC01C-HUGL2 FAB FROM AN HIV-1 NAIVE DONOR IN COMPLEX WITH WITH A GERMLINE-TARGETING GP120 ENGINEERED OUTER DOMAIN EOD-GT8 AT 2.44 A | HIV-1 GP120, ENGINEERED OUTER DOMAIN (EOD), GERMLINE TARGETING, CD4 BINDING SITE, VRC01-CLASS NAIVE HUMAN GERMLINE ANTIBODY, IMMUNE SYSTEM, VIRAL-PROTEIN COMPLEX, IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX
5ijb:B (ASN456) to (MET476) THE LIGAND-FREE STRUCTURE OF THE MOUSE TLR4/MD-2 COMPLEX | LEUCINE-RICH REPEATS, IMMUNE SYSTEM
5ijd:B (ASN456) to (MET476) THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LIPID A COMPLEX | IMMUNE RESPONSE, PROTEIN COMPLEX, NATURAL AGONIST, IMMUNE SYSTEM
3prx:X (GLU158) to (LYS194) STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH CVF AND SSL7 | IMMUNE SYSTEM, COMPLEMENT, STAPHYLOCOCCUS AUREUS, IMMUNE SYSTEM-TOXIN COMPLEX
3prx:Y (GLU158) to (LYS194) STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH CVF AND SSL7 | IMMUNE SYSTEM, COMPLEMENT, STAPHYLOCOCCUS AUREUS, IMMUNE SYSTEM-TOXIN COMPLEX
5it9:W (PRO77) to (THR105) STRUCTURE OF THE YEAST KLUYVEROMYCES LACTIS SMALL RIBOSOMAL SUBUNIT IN COMPLEX WITH THE CRICKET PARALYSIS VIRUS IRES. | IRES, RIBOSOME, SMALL, SUBUNIT
5iwg:A (ASP235) to (GLY267) HDAC2 WITH LIGAND BRD4884 | HDAC HISTONE DEACETYLASE, HYDROLASE
5ix0:A (ASP235) to (GLY267) HDAC2 WITH LIGAND BRD7232 | HDAC HISTONE DEACETYLASE, HYDROLASE
5ix0:C (ASP235) to (GLY267) HDAC2 WITH LIGAND BRD7232 | HDAC HISTONE DEACETYLASE, HYDROLASE
3qa3:E (GLY207) to (ILE240) CRYSTAL STRUCTURE OF A-DOMAIN IN COMPLEX WITH ANTIBODY | IMMUNE SYSTEM- CELL ADHESION COMPLEX
3qa3:I (GLY207) to (ILE240) CRYSTAL STRUCTURE OF A-DOMAIN IN COMPLEX WITH ANTIBODY | IMMUNE SYSTEM- CELL ADHESION COMPLEX
4f36:C (VAL115) to (TRP141) CRYSTAL STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE B FROM TRYPANOSOMA BRUCEI, APO FORM | SSGCID, NIH, NIAID, SBRI, EMERALD BIOSTRUCTURES, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
4f36:B (VAL115) to (THR142) CRYSTAL STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE B FROM TRYPANOSOMA BRUCEI, APO FORM | SSGCID, NIH, NIAID, SBRI, EMERALD BIOSTRUCTURES, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
5j0y:A (LYS148) to (VAL177) BINARY COMPLEX CRYSTAL STRUCTURE OF DNA POLYMERASE BETA WITH T:T MISMATCH AT THE PRIMER TERMINUS | DNA POLYMERASE BETA, MISMATCH EXTENSION, BINARY COMPLEX, TRANSFERASE- DNA COMPLEX
5j1e:C (ALA360) to (PRO392) CRYSTAL STRUCTURE OF A HYDROXYPYRIDONE CARBOXYLIC ACID ACTIVE-SITE RNASE H INHIBITOR IN COMPLEX WITH HIV REVERSE TRANSCRIPTASE | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qk2:A (HIS201) to (LYS224) STRUCTURE-BASED ANALYSIS OF THE INTERACTION BETWEEN THE SIMIAN VIRUS 40 T-ANTIGEN ORIGIN BINDING DOMAIN AND SINGLE-STRANDED DNA | ORIGIN BINDING DOMAIN, DNA REPLICATION, DNA BINDING PROTEIN
3qlh:A (ALA360) to (LYS390) HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH MANICOL AT THE RNASE H ACTIVE SITE AND TMC278 (RILPIVIRINE) AT THE NNRTI BINDING POCKET | RNASE H INHIBITOR, STRUCTURE-BASED DRUG DESIGN, TROPOLONE DERIVATIVES, DIVALENT CATION CHELATOR, NON-NUCLEOSIDE RT INHIBITOR, TRANSFERASE,HYDROLASE-INHIBITOR COMPLEX
4uzu:A (TYR199) to (ALA233) THREE-DIMENSIONAL STRUCTURE OF A VARIANT `TERMAMYL-LIKE' GEOBACILLUS STEAROTHERMOPHILUS ALPHA-AMYLASE AT 1.9 A RESOLUTION | HYDROLASE
4v1a:k (SER160) to (VAL186) STRUCTURE OF THE LARGE SUBUNIT OF THE MAMMALIAN MITOCHONDRIAL RIBOSOME, PART 2 OF 2 | RIBOSOME, TRANSLATION, LARGE RIBOSOMAL SUBUNIT, MITORIBOSOME, MAMMALIAN MITOCHONDRIAL RIBOSOME, CRYO-EM
3qre:A (GLY118) to (ALA136) CRYSTAL STRUCTURE OF AN ENOYL-COA HYDRATASE ECHA12_1 FROM MYCOBACTERIUM MARINUM | STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, MYCOBACTERIUM, TUBERCULOSIS, ENOYL-COA, COENZYME A, HYDRATASE, FATTY ACID METABOLISM, OPPORTUNISTIC INFECTIONS IN HUMANS, ASSOCIATED WITH SWIMMING, FISH-TANK, LYASE
4v27:A (VAL301) to (THR329) STRUCTURE OF THE GH99 ENDO-ALPHA-MANNANASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH MANNOSE-ALPHA-1,3-ISOFAGOMINE | HYDROLASE, GH99, CAZY, MANNAN, BACTEROIDES, POLYSACCHARIDE UTILISATION, ENZYME-CARBOHYDRATE INTERACTION, INHIBITOR, GLYCOSIDASE INHIBITION
4v28:A (VAL301) to (THR329) STRUCTURE OF AN E333Q VARIANT OF THE GH99 ENDO-ALPHA- MANNANASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH MAN-MAN-METHYLUMBELLIFERONE | HYDROLASE, GH99, CAZY, MANNAN, BACTEROIDES, POLYSACCHARIDE UTILISATION, ENZYME-CARBOHYDRATE INTERACTION, SUBSTRATE COMPLEX
3quf:A (ARG272) to (PRO292) THE STRUCTURE OF A FAMILY 1 EXTRACELLULAR SOLUTE-BINDING PROTEIN FROM BIFIDOBACTERIUM LONGUM SUBSP. INFANTIS | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, TRANSPORT PROTEIN
3qy9:A (GLU202) to (THR236) THE CRYSTAL STRUCTURE OF DIHYDRODIPICOLINATE REDUCTASE FROM STAPHYLOCOCCUS AUREUS | ROSSMANN FOLD, REDUCTASE, NADH, NADPH, DIHYDRODIPICOLINATE, OXIDOREDUCTASE
3qyr:A (GLY96) to (ALA114) CRYSTAL STRUCTURE OF ENOYL-COA HYDRATASE ECHA16_2 MYCOBACTERIUM PARATUBERCULOSIS ATCC BAA-968 / K-10 | SSGCID, NIH, NIAID, SBRI, UW, EMERALD BIOSTRUCTURES, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, LYASE
3qyr:B (GLY96) to (ALA114) CRYSTAL STRUCTURE OF ENOYL-COA HYDRATASE ECHA16_2 MYCOBACTERIUM PARATUBERCULOSIS ATCC BAA-968 / K-10 | SSGCID, NIH, NIAID, SBRI, UW, EMERALD BIOSTRUCTURES, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, LYASE
3qyr:C (GLY96) to (ALA114) CRYSTAL STRUCTURE OF ENOYL-COA HYDRATASE ECHA16_2 MYCOBACTERIUM PARATUBERCULOSIS ATCC BAA-968 / K-10 | SSGCID, NIH, NIAID, SBRI, UW, EMERALD BIOSTRUCTURES, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, LYASE
3qyr:E (GLY96) to (ALA114) CRYSTAL STRUCTURE OF ENOYL-COA HYDRATASE ECHA16_2 MYCOBACTERIUM PARATUBERCULOSIS ATCC BAA-968 / K-10 | SSGCID, NIH, NIAID, SBRI, UW, EMERALD BIOSTRUCTURES, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, LYASE
4fn7:A (GLY102) to (ALA120) APO STRUCTURE OF THE MTB ENOYOL COA ISOMERASE (RV0632C) | STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, CROTONASE SUPERFAMILY, ISOMERASE
4fn8:A (GLY102) to (ALA120) CRYSTAL STRUCTURE OF THE MTB ENOYL COA ISOMERASE (RV0632C)IN COMPLEX WITH ACETOACETYL COA | STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, CROTONASE SUPERFAMILY, ISOMERASE
3rh6:A (GLU147) to (VAL177) DNA POLYMERASE BETA MUTANT (Y271) WITH A DIDEOXY-TERMINATED PRIMER WITH AN INCOMING RIBONUCLEOTIDE (RCTP) | POLYMERASE BETA, RIBONUCLEOTIDE INSERTION, TRANSFERASE-DNA COMPLEX
3rik:A (SER351) to (TRP381) THE ACID BETA-GLUCOSIDASE ACTIVE SITE EXHIBITS PLASTICITY IN BINDING 3,4,5,6-TETRAHYDROXYAZEPANE-BASED INHIBITORS: IMPLICATIONS FOR PHARMACOLOGICAL CHAPERONE DESIGN FOR GAUCHER DISEASE | TIM-BARREL, LYSOSOMAL HYDROLASE, HYDROLASE, GLYCOSYLATION, LYSOSOME, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3rik:B (SER351) to (TRP381) THE ACID BETA-GLUCOSIDASE ACTIVE SITE EXHIBITS PLASTICITY IN BINDING 3,4,5,6-TETRAHYDROXYAZEPANE-BASED INHIBITORS: IMPLICATIONS FOR PHARMACOLOGICAL CHAPERONE DESIGN FOR GAUCHER DISEASE | TIM-BARREL, LYSOSOMAL HYDROLASE, HYDROLASE, GLYCOSYLATION, LYSOSOME, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3rik:C (SER351) to (TRP381) THE ACID BETA-GLUCOSIDASE ACTIVE SITE EXHIBITS PLASTICITY IN BINDING 3,4,5,6-TETRAHYDROXYAZEPANE-BASED INHIBITORS: IMPLICATIONS FOR PHARMACOLOGICAL CHAPERONE DESIGN FOR GAUCHER DISEASE | TIM-BARREL, LYSOSOMAL HYDROLASE, HYDROLASE, GLYCOSYLATION, LYSOSOME, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4fz2:A (ASP262) to (ILE288) CRYSTAL STRUCTURE OF THE FOURTH TYPE OF ARCHAEAL TRNA SPLICING ENDONUCLEASE FROM CANDIDATUS MICRARCHAEUM ACIDIPHILUM ARMAN-2 | TRNA SPLICING ENDONUCLEASE, HYDROLASE
4fz2:B (ASP262) to (GLY290) CRYSTAL STRUCTURE OF THE FOURTH TYPE OF ARCHAEAL TRNA SPLICING ENDONUCLEASE FROM CANDIDATUS MICRARCHAEUM ACIDIPHILUM ARMAN-2 | TRNA SPLICING ENDONUCLEASE, HYDROLASE
4gdc:C (GLY418) to (GLY446) CRYSTAL STRUCURE OF OXIDIZED ASPERGILLUS FUMIGATUS UDP-GALACTOPYRANOSE MUTASE COMPLEXED WITH NADPH | FLAVIN ADENINE DINUCLEOTIDE BINDING, NUCLEOTIDE BINDING, MUTASE, ISOMERASE
4gdc:D (GLY418) to (GLY446) CRYSTAL STRUCURE OF OXIDIZED ASPERGILLUS FUMIGATUS UDP-GALACTOPYRANOSE MUTASE COMPLEXED WITH NADPH | FLAVIN ADENINE DINUCLEOTIDE BINDING, NUCLEOTIDE BINDING, MUTASE, ISOMERASE
5thw:B (ILE335) to (ASP364) CRYSTAL STRUCTURE OF AMIDASE, HYDANTOINASE/CARBAMOYLASE FAMILY FROM BURKHOLDERIA MULTIVORANS | SSGCID, BURKHOLDERIA MULTIVORANS, N-CARBAMOYL-L-AMINO-ACID HYDROLASE, AMIDASE, HYDANTOINASE/CARBAMOYLASE FAMILY, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, HYDROLASE
5thw:D (ILE335) to (ASP364) CRYSTAL STRUCTURE OF AMIDASE, HYDANTOINASE/CARBAMOYLASE FAMILY FROM BURKHOLDERIA MULTIVORANS | SSGCID, BURKHOLDERIA MULTIVORANS, N-CARBAMOYL-L-AMINO-ACID HYDROLASE, AMIDASE, HYDANTOINASE/CARBAMOYLASE FAMILY, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, HYDROLASE
1a54:A (LYS215) to (ASN243) PHOSPHATE-BINDING PROTEIN MUTANT A197C LABELLED WITH A COUMARIN FLUOROPHORE AND BOUND TO DIHYDROGENPHOSPHATE ION | PHOSPHOTRANSFERASE, TRANSPORT, COUMARIN, FLUOROPHORE
1nhx:A (MET173) to (VAL190) PEPCK COMPLEX WITH A GTP-COMPETITIVE INHIBITOR | GLUCONEOGENESIS, XANTHINE, INHIBITOR, LYASE
3ehe:B (ASP233) to (THR257) CRYSTAL STRUCTURE OF UDP-GLUCOSE 4 EPIMERASE (GALE-1) FROM ARCHAEOGLOBUS FULGIDUS | PSI-II, NYSGXRC, 11140G, GALE-1, UDP-GLUCOSE 4 EPIMERASE, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, ISOMERASE
2op3:B (ASN67) to (ASP87) THE STRUCTURE OF CATHEPSIN S WITH A NOVEL 2- ARYLPHENOXYACETALDEHYDE INHIBITOR DERIVED BY THE SUBSTRATE ACTIVITY SCREENING (SAS) METHOD | CATHEPSIN S, NONPEPTIDIC, SUBSTRATE ACTIVITY SCREENING, HYDROLASE
3rxz:A (GLY208) to (HIS239) CRYSTAL STRUCTURE OF PUTATIVE POLYSACCHARIDE DEACETYLASE FROM MYCOBACTERIUM SMEGMATIS | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, CARBOHYDRATE ESTERASE FAMILY 4, HYDROLASE
3rxz:C (GLY208) to (HIS239) CRYSTAL STRUCTURE OF PUTATIVE POLYSACCHARIDE DEACETYLASE FROM MYCOBACTERIUM SMEGMATIS | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, CARBOHYDRATE ESTERASE FAMILY 4, HYDROLASE
3rxz:D (GLY208) to (HIS239) CRYSTAL STRUCTURE OF PUTATIVE POLYSACCHARIDE DEACETYLASE FROM MYCOBACTERIUM SMEGMATIS | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, CARBOHYDRATE ESTERASE FAMILY 4, HYDROLASE
2p1p:B (MET115) to (SER139) MECHANISM OF AUXIN PERCEPTION BY THE TIR1 UBIQUITIN LIGASE | F-BOX, LEUCINE RICH REPEAT, SIGNALING PROTEIN
1b3q:A (ARG354) to (GLY386) CRYSTAL STRUCTURE OF CHEA-289, A SIGNAL TRANSDUCING HISTIDINE KINASE | HISTINE KINASE, SIGNAL TRANSDUCTION, CHEMOTAXIS, MULTI-DOMAINS PROTEIN, TRANSFERASE
4hmp:A (PHE255) to (TYR276) CRYSTAL STRUCTURE OF IRON UPTAKE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN PIAA FROM STREPTOCOCCUS PNEUMONIAE TIGR4 | CLASS III SUBSTRATE BINDING PROTEIN, ALPHA AND BETA PROTEIN, PERIPLASMIC BINDING PROTEIN TYPE III FOLD, IRON UPTAKE ABC TRANSPORTER SYSTEM SUBSTRATE-BINDING PROTEIN, HYDROXAMATE SIDEROPHORE, MEMBRANE-ANCHORED LIPOPROTEIN, TRANSPORT PROTEIN
4xbj:B (ALA4) to (VAL33) Y274F ALANINE RACEMASE FROM E. COLI INHIBITED BY L-ALA-P | ISOMERASE, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
2pma:B (PRO142) to (PRO159) STRUCTURAL GENOMICS, THE CRYSTAL STRUCTURE OF A PROTEIN LPG0085 WITH UNKNOWN FUNCTION (DUF785) FROM LEGIONELLA PNEUMOPHILA SUBSP. PNEUMOPHILA STR. PHILADELPHIA 1. | APC86035.2, PROTEIN LPG0085, DUF785, LEGIONELLA PNEUMOPHILA SUBSP. PNEUMOPHILA STR. PHILADELPHIA 1, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
2pzi:A (GLY237) to (ASP276) CRYSTAL STRUCTURE OF PROTEIN KINASE PKNG FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH TETRAHYDROBENZOTHIOPHENE AX20017 | SERINE/THREONINE-PROTEIN KINASE, ATP-RECOGNITION, KINASE-INHIBITOR COMPLEX, RUBREDOXIN FOLD, TPR DOMAIN, TRANSFERASE
2c8h:B (GLY171) to (ALA195) STRUCTURE OF THE PN LOOP Q182A MUTANT C3BOT1 EXOENZYME (NAD-BOUND STATE, CRYSTAL FORM I) | C3 EXOENZYME, ARTT MOTIF, ADP-RIBOSYLTRANSFERASE, BACTERIAL TOXINS, PN LOOP, NAD, GLYCOSYLTRANSFERASE, TRANSFERASE
4ihf:B (ALA2) to (GLY19) CHASING ACYL CARRIER PROTEIN THROUGH A CATALYTIC CYCLE OF LIPID A PRODUCTION | ACYL CARRIER PROTEIN, LEFT HANDED BETA HELIX, LPXD, ACYLTRANSFERASE, LIPID A, PROTEIN-PROTEIN COMPLEX, ACP RECOGNITION DOMAIN, ACP MEDIATED PRODUCT RELEASE, TRANSFERASE-LIPID BINDING PROTEIN COMPLEX
2d3n:A (TYR203) to (ALA237) CRYSTAL STRUCTURE OF MALTOHEXAOSE-PRODUCING AMYLASE FROM BACILLUS SP.707 COMPLEXED WITH MALTOHEXAOSE | PROTEIN-CARBOHYDRATE COMPLEX, LIGAND BINDING, MALTOHEXAOSE, HYDROLASE
3gxd:B (SER351) to (TRP381) CRYSTAL STRUCTURE OF APO ACID-BETA-GLUCOSIDASE PH 4.5 | HYDROLASE, ALTERNATIVE INITIATION, DISEASE MUTATION, DISULFIDE BOND, GAUCHER DISEASE, GLYCOPROTEIN, GLYCOSIDASE, ICHTHYOSIS, LIPID METABOLISM, LYSOSOME, MEMBRANE, SPHINGOLIPID METABOLISM
3gxm:B (SER351) to (TRP381) CRYSTAL STRUCTURE OF ACID-BETA-GLUCOSIDASE AT PH 4.5, PHOSPHATE CRYSTALLIZATION CONDITION | HYDROLASE, ALTERNATIVE INITIATION, DISEASE MUTATION, DISULFIDE BOND, GAUCHER DISEASE, GLYCOPROTEIN, GLYCOSIDASE, ICHTHYOSIS, LIPID METABOLISM, LYSOSOME, MEMBRANE, SPHINGOLIPID METABOLISM
1quj:A (LYS215) to (ASN243) PHOSPHATE-BINDING PROTEIN MUTANT WITH ASP 137 REPLACED BY GLY COMPLEX WITH CHLORINE AND PHOSPHATE | BINDING PROTEIN, PHOSPHATE TRANSPORT
2v8d:A (LEU359) to (GLN390) CRYSTAL STRUCTURE OF MUTANT E159A OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI | HYDROLASE, DI-ZINC CENTER, AMIDOHYDROLASE
3ul9:A (ARG67) to (LEU85) STRUCTURE OF THE TV3 MUTANT M41E | LRR, PROTEIN BINDING, MD-2, EXTRACELLULAR MATRIX, IMMUNE SYSTEM
2f61:A (SER351) to (TRP381) CRYSTAL STRUCTURE OF PARTIALLY DEGLYCOSYLATED ACID BETA-GLUCOSIDASE | ALPHA/BETA, TIM BARREL, IMMUNOGLOBULIN FOLD, HYDROLASE
2f61:B (SER351) to (TRP381) CRYSTAL STRUCTURE OF PARTIALLY DEGLYCOSYLATED ACID BETA-GLUCOSIDASE | ALPHA/BETA, TIM BARREL, IMMUNOGLOBULIN FOLD, HYDROLASE
4z1o:B (GLU3) to (VAL32) HYPOXANTHINE-GUANINE-XANTHINE PHOSPHORIBOSYLTRANSFERASE (HGXPRT) FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH ALPHA- PHOSPHORIBOSYLPYROPHOSPHORIC ACID (PRPP) AND MAGNESIUM | TRANSFERASE, PHOSPHORIBOSYLTRANSFERASE, HGXPRT, HGPRT
1g88:C (VAL437) to (ALA486) S4AFL3ARG515 MUTANT | TRANSCRIPTIONAL FACTOR, L3 LOOP MUTANT
2fkl:B (VAL143) to (MET170) STRUCTURE OF THE ALZHEIMER'S AMYLOID PRECURSOR PROTEIN (APP) COPPER BINDING DOMAIN (RESIDUES 126- 189 OF APP) | ALPHA-BETA TWO-LAYERED SANDWICH, METAL BINDING PROTEIN
1sg3:A (MET1) to (ASP24) STRUCTURE OF ALLANTOICASE | ALLANTOICASE, JELLY ROLL, HEXAMER, HYDROLASE
1gvo:A (ALA71) to (ARG106) STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE AND COMPLEXED WITH 2,4 DINITROPHENOL | FLAVOENZYME, EXPLOSIVE DEGRADATION, STEROID BINDING, OXIDOREDUCTASE
1gvo:A (THR147) to (SER182) STRUCTURE OF PENTAERYTHRITOL TETRANITRATE REDUCTASE AND COMPLEXED WITH 2,4 DINITROPHENOL | FLAVOENZYME, EXPLOSIVE DEGRADATION, STEROID BINDING, OXIDOREDUCTASE
2w3p:A (GLY138) to (VAL157) BOXC CRYSTAL STRUCTURE | COA, BOXC, LYASE, CROTONASE, RING CLEAVING, BURKHOLDERIA XENOVORANS LB400 CROTONASE
2w3p:B (GLY138) to (VAL157) BOXC CRYSTAL STRUCTURE | COA, BOXC, LYASE, CROTONASE, RING CLEAVING, BURKHOLDERIA XENOVORANS LB400 CROTONASE
1til:D (THR54) to (ALA82) CRYSTAL STRUCTURES OF THE ADP AND ATP BOUND FORMS OF THE BACILLUS ANTI-SIGMA FACTOR SPOIIAB IN COMPLEX WITH THE ANTI-ANTI-SIGMA SPOIIAA:POISED FOR PHOSPHORYLATION COMPLEX WITH ATP, CRYSTAL FORM II | SPOIIAB, SPOIIA, ANTI-SIGMA, ANTI-ANTI-SIGMA, SPORULATION, SERINE KINASEA, TRANSCRIPTION
4lif:A (HIS202) to (GLY226) CRYSTAL STRUCTURE OF THE JCV LARGE T-ANTIGEN ORIGIN BINDING DOMAIN | ORIGIN BINDING DOMAIN, REPLICATION, POLYOMAVIRUS, HYDROLASE, DNA BINDING PROTEIN
3irx:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH THE NON-NUCLEOSIDE RT INHIBITOR (E)-S-METHYL 5-(1-(3,7-DIMETHYL-2-OXO-2,3-DIHYDROBENZO[D]OXAZOL-5-YL)-5- (5-METHYL-1,3,4-OXADIAZOL-2-YL)PENT-1-ENYL)-2-METHOXY-3- METHYLBENZOTHIOATE. | NNRTI, NONNUCLEOSIDE INHIBITOR, AIDS, HIV, P51/P66, ADAM, ASPARTYL PROTEASE, CELL MEMBRANE, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER, TRANSFERASE-HYDROLASE COMPLEX
1tl3:A (HIS361) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW450557 | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NNRTI, GW450557, DRUG DESIGN, TRANSFERASE
1hqe:A (HIS361) to (PRO392) HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 | NUCLEOTIDYLTRANSFERASE
3vq2:B (ASN456) to (MET476) CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LPS COMPLEX | LEUCINE RICH REPEAT MD-2 RELATED LIPID RECOGNITION, RECEPTOR INNATE IMMUNITY, LIPID BINDING, GLYCOSYLATION, SECRETED, IMMUNE SYSTEM
4lsl:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH (E)- 3-(3-(4-CHLORO-2-(2-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)ETHOXY) PHENOXY)PHENYL)ACRYLONITRILE (JLJ476), A NON-NUCLEOSIDE INHIBITOR | POLYMERASE, TRANSFERASE, HYDROLASE, RNASEH, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2hy5:C (GLY479) to (LEU502) CRYSTAL STRUCTURE OF DSREFH | DSRE, DSRF, DSRH, SULFUR, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, BERKELEY STRUCTURAL GENOMICS CENTER, BSGC, TRANSFERASE
5aed:B (PRO336) to (GLU366) A BACTERIAL PROTEIN STRUCTURE IN GLYCOSIDE HYDROLASE FAMILY 31 | HYDROLASE, GH31, ALPHA-SULFOQUINOVOSIDASE
5aed:B (GLU369) to (ASP405) A BACTERIAL PROTEIN STRUCTURE IN GLYCOSIDE HYDROLASE FAMILY 31 | HYDROLASE, GH31, ALPHA-SULFOQUINOVOSIDASE
3wqt:C (ASP97) to (ARG130) STAPHYLOCOCCUS AUREUS FTSA COMPLEXED WITH AMPPNP | ACTIN-LIKE FOLD, STRUCTURAL GENOMICS
1jn3:A (LYS148) to (VAL177) FIDELITY PROPERTIES AND STRUCTURE OF M282L MUTATOR MUTANT OF DNA POLYMERASE: SUBTLE STRUCTURAL CHANGES INFLUENCE THE MECHANISM OF NUCLEOTIDE DISCRIMINATION | DNA POLYMERASE BETA (FRAGMENT), MUTANT, NUCLEOTIDE DISCRIMINATION, TRANSFERASE
4n6l:A (ARG8) to (HIS48) CRYSTAL STRUCTURE OF HUMAN CYSTATIN E/M | CYSTEINE PROTEASE INHIBITOR, LEGUMAIN, ASPARAGINYL ENDOPEPTIDASE, REACTIVE CENTER LOOP, PAPAIN, CATHEPSIN, CANCER, CYSTATIN FOLD, PROTEASE INHIBITOR, HYDROLASE INHIBITOR
1w7n:A (GLY188) to (ASP213) CRYSTAL STRUCTURE OF HUMAN KYNURENINE AMINOTRANSFERASE I IN PMP FORM | KYNURENINE PATHWAY, KYNURENIC ACID, PLP-ENZYME, AMINOTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIDOXAL PHOSPHATE, TRANSFERASE
4nbk:A (ALA132) to (GLN161) TAILORING SMALL MOLECULES FOR AN ALLOSTERIC SITE ON PROCASPASE-6 | PROCASPSE-6, CASPASE-6 ZYMOGEN, ALLOSTERIC, STRUCTURE BASED DRUG DESIGN, CYSTEINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4nbk:B (ALA132) to (GLN161) TAILORING SMALL MOLECULES FOR AN ALLOSTERIC SITE ON PROCASPASE-6 | PROCASPSE-6, CASPASE-6 ZYMOGEN, ALLOSTERIC, STRUCTURE BASED DRUG DESIGN, CYSTEINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1k5d:F (ASN42) to (PHE67) CRYSTAL STRUCTURE OF RAN-GPPNHP-RANBP1-RANGAP COMPLEX | RAN, RANBP1, RANGAP, GAP, SIGNAL TRANSDUCTION, NUCLEAR TRANSPORT, GTP HYDROLYSIS, GROUND STATE, COMPLEX (GTP- BINDING/GTPASE ACTIVATION), SIGNALING PROTEIN/SIGNALING ACTIVATOR COMPLEX
1k5d:I (ASN42) to (PHE67) CRYSTAL STRUCTURE OF RAN-GPPNHP-RANBP1-RANGAP COMPLEX | RAN, RANBP1, RANGAP, GAP, SIGNAL TRANSDUCTION, NUCLEAR TRANSPORT, GTP HYDROLYSIS, GROUND STATE, COMPLEX (GTP- BINDING/GTPASE ACTIVATION), SIGNALING PROTEIN/SIGNALING ACTIVATOR COMPLEX
2nt1:A (SER351) to (ASP380) STRUCTURE OF ACID-BETA-GLUCOSIDASE AT NEUTRAL PH | ACID-BETA-GLUCOSIDASE, CEREZYME, GLUCOSYLCERAMIDE, GAUCHER DISEASE, HYDROLASE
2nt1:D (SER351) to (TRP381) STRUCTURE OF ACID-BETA-GLUCOSIDASE AT NEUTRAL PH | ACID-BETA-GLUCOSIDASE, CEREZYME, GLUCOSYLCERAMIDE, GAUCHER DISEASE, HYDROLASE
2yne:A (LEU277) to (GLU294) PLASMODIUM VIVAX N-MYRISTOYLTRANSFERASE IN COMPLEX WITH A BENZOTHIOPHENE INHIBITOR | TRANSFERASE, MYRISTOYLATION, MALARIA
2yne:B (LEU277) to (GLU294) PLASMODIUM VIVAX N-MYRISTOYLTRANSFERASE IN COMPLEX WITH A BENZOTHIOPHENE INHIBITOR | TRANSFERASE, MYRISTOYLATION, MALARIA
1m51:A (MET173) to (VAL190) PEPCK COMPLEX WITH A GTP-COMPETITIVE INHIBITOR | GLUCONEOGENESIS, XANTHINE, INHIBITOR, LYASE
5da0:A (ASP442) to (GLY472) STRUCTURE OF THE THE SLC26 TRANSPORTER SLC26DG IN COMPLEX WITH A NANOBODY | MEMBRANE TRANSPORT PROTEIN, NANOBODY COMPLEX, TRANSPORT PROTEIN
3l5a:A (GLU134) to (ILE171) CRYSTAL STRUCTURE OF A PROBABLE NADH-DEPENDENT FLAVIN OXIDOREDUCTASE FROM STAPHYLOCOCCUS AUREUS | OLD YELLOW ENZYME FAMILY, OYE-LIKE FMN-BINDING DOMAIN, TIM BARREL, OXIDOREDUCTASE
4pn0:C (ARG112) to (THR160) STRUCTURE OF S. POMBE PCT1 RNA TRIPHOSPHATASE | MRNA TRIPHOSPHATASE, HYDROLASE, POLYNUCLEOTIDE 5' TRIPHOSPHATASE, MRNA PROCESSING, MRNA CAPPING, DIMER
4pnl:B (LEU954) to (LEU995) CRYSTAL STRUCTURE OF TNKS-2 IN COMPLEX WITH DR2313. | PARP, TRANSFERASE
4pns:B (LEU954) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH INH2BP. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
3lam:A (HIS361) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH N1-PROPYL PYRIMIDINEDIONE NON-NUCLEOSIDE INHIBITOR | HIV, RT, NNRTI, TRANSFERASE
1z7n:H (ASP155) to (GLU172) ATP PHOSPHORIBOSYL TRANSFERASE (HISZG ATP-PRTASE) FROM LACTOCOCCUS LACTIS WITH BOUND PRPP SUBSTRATE | ATP-PRT, PRPP, HISTIDINE BIOSYNTHESIS, TRANSFERASE, HISZG, ALLOSTERIC
4ap0:A (ILE19) to (SER39) THE MITOTIC KINESIN EG5 IN COMPLEX WITH MG-ADP AND ISPINESIB | MOTOR PROTEIN
4ap0:C (ILE19) to (SER39) THE MITOTIC KINESIN EG5 IN COMPLEX WITH MG-ADP AND ISPINESIB | MOTOR PROTEIN
4apr:E (ASP120) to (LYS160) STRUCTURES OF COMPLEXES OF RHIZOPUSPEPSIN WITH PEPSTATIN AND OTHER STATINE-CONTAINING INHIBITORS | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3b0n:A (ASN114) to (ILE140) Q448K MUTANT OF ASSIMILATORY NITRITE REDUCTASE (NII3) FROM TOBBACO LEAF | SIROHEME, FE4S4 BINDING PROTEIN, OXIDOREDUCTASE
5en5:B (ARG239) to (LEU270) APO STRUCTURE OF BACTERIAL EFFLUX PUMP. | EFFLUX PUMP, TRANSPORT PROTEIN
3moe:A (MET173) to (ILE190) THE STRUCTURE OF RAT CYTOSOLIC PEPCK MUTANT A467G IN COMPLEX WITH BETA-SULFOPYRUVATE AND GTP | KINASE, GLUCONEOGENESIS, LYASE
3brf:A (GLN477) to (GLN492) CSL (LAG-1) BOUND TO DNA WITH LIN-12 RAM PEPTIDE, C2221 | PROTEIN-DNA COMPLEX, SIGNALING, TRANSCRIPTION, NOTCH, DNA- BINDING, ANK REPEAT, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, EGF-LIKE DOMAIN, GLYCOPROTEIN, MEMBRANE, TRANSMEMBRANE, DNA BINDING PROTEIN/DNA COMPLEX
3mz4:B (ASP233) to (ALA266) CRYSTAL STRUCTURE OF D101L MN2+ HDAC8 COMPLEXED WITH M344 | HYDROLASE, METALLOHYDROLASE, MANAGANESE(II), ARGINASE-LIKE
3c6n:B (MET115) to (SER139) SMALL MOLECULE AGONISTS AND ANTAGONISTS OF F-BOX PROTEIN- SUBSTRATE INTERACTIONS IN AUXIN PERCEPTION AND SIGNALING | AUXIN, UBIQUITIN LIGASE, SMALL MOLECULES, PLANT PHYSIOLOGY, CHEMICAL BIOLOGY, AUXIN SIGNALING PATHWAY, CHROMOSOME PARTITION, CYTOPLASM, CYTOSKELETON, DEVELOPMENTAL PROTEIN, ETHYLENE SIGNALING PATHWAY, NUCLEUS, UBL CONJUGATION PATHWAY, CELL CYCLE, LEUCINE-RICH REPEAT, PLANT DEFENSE, SIGNALING PROTEIN
4c68:B (LEU277) to (GLU294) PLASMODIUM VIVAX N-MYRISTOYLTRANSFERASE IN COMPLEX WITH A PEPTIDOMIMETIC INHIBITOR | TRANSFERASE, MYRISTOYLATION, MALARIA
4caf:A (LEU277) to (GLU294) PLASMODIUM VIVAX N-MYRISTOYLTRANSFERASE IN COMPLEX WITH A BENZOTHIOPHENE INHIBITOR (COMPOUND 34A) | TRANSFERASE, MYRISTOYLATION, MALARIA, INHIBITOR, BENZOTHIOPHENE
4rq6:A (GLU147) to (VAL177) HUMAN DNA POLYMERASE BETA WITH GAPPED DNA CONTAINING AN 8-OXO-7,8- DIHYDRO-GUANINE(8-OXOG) AND DATP SOAKED WITH MGCL2 FOR 80 S | X-FAMILY, POL BETA, TRANSFERASE-DNA COMPLEX
4tju:C (PHE956) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 3,4-CPQ-5-C. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
4tjw:B (LEU954) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH PJ-34. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
4tkf:B (PHE956) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH IWR-1. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
4tkf:C (LEU954) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH IWR-1. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
4tki:B (LEU954) to (LEU995) CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH BSI-201. | POLY(ADP-RIBOSYLATION) POLYMERASE (PARP), TRANSFERASE
3oq8:A (GLY190) to (THR223) CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BRUCELLA MELITENSIS, BOUND TO THE PRODUCT MIMIC MALONATE | SSGCID, LYASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3oq8:B (GLY190) to (THR223) CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BRUCELLA MELITENSIS, BOUND TO THE PRODUCT MIMIC MALONATE | SSGCID, LYASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3oq8:C (GLY190) to (THR223) CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BRUCELLA MELITENSIS, BOUND TO THE PRODUCT MIMIC MALONATE | SSGCID, LYASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3oq8:D (GLY190) to (THR223) CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BRUCELLA MELITENSIS, BOUND TO THE PRODUCT MIMIC MALONATE | SSGCID, LYASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3dtb:A (MET173) to (ILE190) THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH PHOSPHOGLYCOLATE AND GDP | KINASE, GLUCONEOGENESIS, LYASE, DECARBOXYLASE, GTP-BINDING, NUCLEOTIDE-BINDING
3p67:A (ALA71) to (ARG106) T26S MUTANT OF PENTAERYTHRITOL TETRANITRATE REDUCTASE CONTAINING A BOUND ACETATE MOLECULE | OLD YELLOW ENZYME FAMILY, ALPHA,BETA BARREL, OXIDOREDUCTASE
3p84:A (ALA71) to (ARG106) Y351A MUTANT OF PENTAERYTHRITOL TETRANITRATE REDUCTASE CONTAINING A BOUND ACETATE MOLECULE | OLD YELLOW ENZYME FAMILY, ALPHA, BETA BARREL, OXIDOREDUCTASE
3e5b:A (GLY190) to (THR223) 2.4 A CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BRUCELLA MELITENSIS | BRUCELLA, MELITENSIS, ISOCITRATE, LYASE, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID
3e5b:B (GLY190) to (THR223) 2.4 A CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BRUCELLA MELITENSIS | BRUCELLA, MELITENSIS, ISOCITRATE, LYASE, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID
3e5b:C (GLY190) to (THR223) 2.4 A CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM BRUCELLA MELITENSIS | BRUCELLA, MELITENSIS, ISOCITRATE, LYASE, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID
3pco:B (ARG767) to (SER792) CRYSTAL STRUCTURE OF E. COLI PHENYLALANINE-TRNA SYNTHETASE COMPLEXED WITH PHENYLALANINE AND AMP | AMINOACYLATION, TRNA-BINDING, DNA-BINDING DOMAIN, FOUR-HELIX BUNDLE, AMINOACYL-TRNA SYNTHETASE, ATP-BINDING, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS
4ufw:A (LEU277) to (GLU294) PLASMODIUM VIVAX N-MYRISTOYLTRANSFERASE IN COMPLEX WITH A PYRIDYL INHIBITOR (COMPOUND 22) | TRANSFERASE, MYRISTOYLATION, MALARIA, INHIBITOR, PYRIDYL
4ufw:B (LEU277) to (GLU294) PLASMODIUM VIVAX N-MYRISTOYLTRANSFERASE IN COMPLEX WITH A PYRIDYL INHIBITOR (COMPOUND 22) | TRANSFERASE, MYRISTOYLATION, MALARIA, INHIBITOR, PYRIDYL
3pn1:A (ASP83) to (PRO115) NOVEL BACTERIAL NAD+-DEPENDENT DNA LIGASE INHIBITORS WITH BROAD SPECTRUM POTENCY AND ANTIBACTERIAL EFFICACY IN VIVO | ATP GRASP FOLD, LIGASE, DNA, BACTERIA, LIGASE-LIGASE INHIBITOR COMPLEX
4utf:A (VAL301) to (THR329) STRUCTURE OF THE GH99 ENDO-ALPHA-MANNOSIDASE FROM BACTEROIDES XYLANISOLVENS IN COMPLEX WITH MANNOSE-ALPHA-1, 3-ISOFAGOMINE AND ALPHA-1,2-MANNOBIOSE | HYDROLASE, BACTEROIDES, ALPHA-MANNOSIDASE, POLYSACCHARIDE UTILISATION LOCUS, MANNOSE, MANNAN, BIOCATALYSIS, YEAST, CATALYTIC DOMAIN, CARBOHYDRATE CONFORMATION, CAZY, GLYCOSIDE HYDROLASE
5ijc:A (ASN456) to (MET476) THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/NEOSEPTIN-3 COMPLEX | IMMUNE RESPONSE, PROTEIN COMPLEX, SMALL MOLECULE AGONIST, IMMUNE SYSTEM
5j0o:A (LYS148) to (VAL177) BINARY COMPLEX CRYSTAL STRUCTURE OF DNA POLYMERASE BETA WITH A:A MISMATCH AT THE PRIMER TERMINUS | DNA POLYMERASE BETA, MISMATCH EXTENSION, BINARY COMPLEX, TRANSFERASE- DNA COMPLEX
3qo9:A (ALA360) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH TSAO-T, A NON-NUCLEOSIDE RT INHIBITOR (NNRTI) | AIDS, HIV, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, NONNUCLEOSIDE, NNRTI, HYDROLASE, HYDROLASE- INHIBITOR COMPLEX
4fgn:B (HIS201) to (GLY225) CRYSTAL STRUCTURE OF THE SV40 LARGE T-ANTIGEN ORIGIN BINING DOMAIN BOUND TO SITE I DNA | ORIGIN BINDING DOMAIN, DNA BINDING PROTEIN-DNA COMPLEX
3ril:A (SER351) to (TRP381) THE ACID BETA-GLUCOSIDASE ACTIVE SITE EXHIBITS PLASTICITY IN BINDING 3,4,5,6-TETRAHYDROXYAZEPANE-BASED INHIBITORS: IMPLICATIONS FOR PHARMACOLOGICAL CHAPERONE DESIGN FOR GAUCHER DISEASE | TIM-BARREL, LYSOSOMAL HYDROLASE, HYDROLASE, GLYCOSYLATION, LYSOSOME, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ril:B (SER351) to (TRP381) THE ACID BETA-GLUCOSIDASE ACTIVE SITE EXHIBITS PLASTICITY IN BINDING 3,4,5,6-TETRAHYDROXYAZEPANE-BASED INHIBITORS: IMPLICATIONS FOR PHARMACOLOGICAL CHAPERONE DESIGN FOR GAUCHER DISEASE | TIM-BARREL, LYSOSOMAL HYDROLASE, HYDROLASE, GLYCOSYLATION, LYSOSOME, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ril:D (SER351) to (TRP381) THE ACID BETA-GLUCOSIDASE ACTIVE SITE EXHIBITS PLASTICITY IN BINDING 3,4,5,6-TETRAHYDROXYAZEPANE-BASED INHIBITORS: IMPLICATIONS FOR PHARMACOLOGICAL CHAPERONE DESIGN FOR GAUCHER DISEASE | TIM-BARREL, LYSOSOMAL HYDROLASE, HYDROLASE, GLYCOSYLATION, LYSOSOME, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4gnq:A (MET173) to (ILE190) STRUCTURE OF RAT CYTOSOLIC PEPCK LD_3G IN COMPLEX WITH OXALATE AND GTP | KINASE, GLUCONEOGENESIS, LYASE