1nbq:A (ARG181) to (PRO201) CRYSTAL STRUCTURE OF HUMAN JUNCTIONAL ADHESION MOLECULE TYPE 1 | REOVIRUS RECEPTOR, ADHESION MOLECULE, TIGHT JUNCTION FORMATION, IMMUNOGLOBULIN SUPERFAMILY, IMMUNE SYSTEM
1ncb:H (GLY164) to (THR192) CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE | HYDROLASE(O-GLYCOSYL)
4wfn:K (ASP72) to (LEU115) CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT (50S) OF DEINOCOCCUS RADIODURANS CONTAINING A THREE RESIDUE INSERTION IN L22 IN COMPLEX WITH ERYTHROMYCIN | RIBOSOME, ANTIBIOTICS, RRESISTANCE, ERYTHROMYCIN
4wg2:C (GLY402) to (LYS452) P411BM3-CIS T438S I263F REGIOSELECTIVE C-H AMINATION CATALYST | P411BM3-CIS, ENGINEERING, CATALYSIS, OXIDOREDUCTASE
2ams:A (ASP11) to (ALA76) STRUCUTRE OF THE OXIDIZED HIPIP FROM THERMOCHROMATIUM TEPIDUM AT 1.4 ANGSTROM RESOLUTION | IRON-SULFUR PROTEIN, ELECTRON TRANSPORT
4gyz:C (LYS173) to (LYS195) MUS MUSCULUS TDP2 BOUND TO DAMP AND MG2+ | PROTEIN-DNA COMPLEX, DNA REPAIR, 5'-DNA END PROCESSING, ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE DOMAIN, EEP DOMAIN, 5'-DNA END RECOGNITION, HYDROLASE
1adj:B (GLY385) to (ARG406) HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH HISTIDINE | AMINO ACID, HISTIDINE, COMPLEX (TRNA SYNTHETASE/PEPTIDE)
1adj:C (GLY385) to (ARG406) HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH HISTIDINE | AMINO ACID, HISTIDINE, COMPLEX (TRNA SYNTHETASE/PEPTIDE)
1adj:D (GLY385) to (ARG406) HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH HISTIDINE | AMINO ACID, HISTIDINE, COMPLEX (TRNA SYNTHETASE/PEPTIDE)
2olq:A (SER98) to (THR139) HOW DOES AN ENZYME RECOGNIZE CO2? | PHOSPHOENOLPYRUVATE CARBOXYKINASE, CO2, LYASE
1ai9:A (LYS161) to (TYR186) CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE | OXIDOREDUCTASE, ANTIFUNGAL TARGET, REDUCTASE
4h23:A (GLY402) to (LYS452) CYTOCHROME P411BM3-CIS CYCLOPROPANATION CATALYST | CYTOCHROME P450, ENZYMATIC CYCLOPROPANATION, DIRECTED EVOLUTION, NON- NATURAL FUNCTION, OXIDOREDUCTASE
4h24:C (GLY402) to (LYS452) CYTOCHROME P450BM3-CIS CYCLOPROPANATION CATALYST | CYTOCHROME P450, ENZYMATIC CYCLOPROPANATION, DIRECTED EVOLUTION, NON- NATURAL FUNCTION, OXIDOREDUCTASE
1aoe:A (LYS161) to (TYR186) CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 1,3-DIAMINO-7-(1-ETHYEPROPYE)-7H-PYRRALO-[3,2- F]QUINAZOLINE (GW345) | OXIDOREDUCTASE, ANTIFUNGAL TARGET, REDUCTASE
1aq2:A (SER98) to (THR139) PHOSPHOENOLPYRUVATE CARBOXYKINASE | KINASE, TRANSPHOSPHORYLATING, P-LOOP, PROTEIN-ATP COMPLEX, NUCLEOTIDE-TRIPHOSPHATE HYDROLASE, LYASE, GLUCONEOGENESIS
4h4k:C (PRO680) to (TRP708) STRUCTURE OF THE CMR2-CMR3 SUBCOMPLEX OF THE CMR RNA-SILENCING COMPLEX | FERREDOXIN, PALM, RAMP, REPEAT ASSOCIATED MYSTERIOUS PROTEIN, POLYMERASE, NUCLEASE, RNA-INTERFERENCE, CMR PROTEINS CRISPR RNA, RNA BINDING PROTEIN
3el3:A (ASP413) to (HIS462) DISTINCT MONOOXYGENASE AND FARNESENE SYNTHASE ACTIVE SITES IN CYTOCHROME P450 170A1 | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP170A1, ANTIBIOTIC BIOSYNTHESIS, FARNESENE SYNTHASE, HEME, IRON, METAL-BINDING, MONOOXYGENASE
4h89:A (THR40) to (TYR76) THE STRUCTURE OF A GCN5-RELATED N-ACETYLTRANSFERASE FROM KRIBBELLA FLAVIDA | N-ACYLTRANSFERASE SUPERFAMILY, STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, PFAM:PF00583, PUTATIVE ACETYLTRANSFERASE, TRANSFERASE
4h97:A (LYS161) to (TYR186) CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 5- {3-[3-METHOXY-5-(4-METHYLPHENYL)PHENYL]BUT-1-YN-1-YL}-6- METHYLPYRIMIDINE-2,4-DIAMINE (UCP111D4M) | ANTIFUNGAL AGENTS, CANDIDA ALBICANS, DRUG DESIGN, ENZYME INHIBITORS, FUNGAL PROTEINS, TETRAHYDROFOLATE DEHYDROGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
4h97:B (LYS161) to (TYR186) CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 5- {3-[3-METHOXY-5-(4-METHYLPHENYL)PHENYL]BUT-1-YN-1-YL}-6- METHYLPYRIMIDINE-2,4-DIAMINE (UCP111D4M) | ANTIFUNGAL AGENTS, CANDIDA ALBICANS, DRUG DESIGN, ENZYME INHIBITORS, FUNGAL PROTEINS, TETRAHYDROFOLATE DEHYDROGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
4wtv:A (PRO104) to (PRO139) CRYSTAL STRUCTURE OF THE PHOSPHATIDYLINOSITOL 4-KINASE IIBETA | LIPID KINASE, PHOSPHATIDYL INOSITOL, TRANSFERASE, HYDROLASE
1nyq:A (SER30) to (THR63) STRUCTURE OF STAPHYLOCOCCUS AUREUS THREONYL-TRNA SYNTHETASE COMPLEXED WITH AN ANALOGUE OF THREONYL ADENYLATE | THREONYL-TRNA SYNTHETASE, ADENYLATE, LIGASE
1b0y:A (ASN11) to (ALA78) MUTANT H42Q OF HIPIP FROM CHROMATIUM VINOSUM AT 0.93A | ELECTRON TRANSFER PROTEIN, ATOMIC RESOLUTION, DIRECT METHODS IRON- SULPHUR CLUSTER, METALLOPROTEIN, ELECTRON TRANSPORT
1nyr:B (SER30) to (THR63) STRUCTURE OF STAPHYLOCOCCUS AUREUS THREONYL-TRNA SYNTHETASE COMPLEXED WITH ATP | THREONYL-TRNA SYNTHETASE, ATP, THREONINE, LIGASE
3er3:E (GLY303) to (SER325) THE ACTIVE SITE OF ASPARTIC PROTEINASES | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3er5:E (GLY303) to (SER325) THE ACTIVE SITE OF ASPARTIC PROTEINASES | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1b5f:B (GLY302) to (GLU324) NATIVE CARDOSIN A FROM CYNARA CARDUNCULUS L. | HYDROLASE, ASPARTIC PROTEINASE
1b5f:D (GLY302) to (GLU324) NATIVE CARDOSIN A FROM CYNARA CARDUNCULUS L. | HYDROLASE, ASPARTIC PROTEINASE
4hes:B (ALA0) to (ILE43) STRUCTURE OF A BETA-LACTAMASE CLASS A-LIKE PROTEIN FROM VEILLONELLA PARVULA. | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, BETA-LACTAMASE CLASS A-LIKE, COG COG2367, HYDROLASE
2bkt:A (GLY309) to (LEU331) CRYSTAL STRUCTURE OF RENIN-PF00257567 COMPLEX | RENIN, ASPARTYL PROTEASE, HYDROLASE
2bkt:B (GLY309) to (LEU331) CRYSTAL STRUCTURE OF RENIN-PF00257567 COMPLEX | RENIN, ASPARTYL PROTEASE, HYDROLASE
3s7s:A (GLY439) to (PRO494) CRYSTAL STRUCTURE OF HUMAN PLACENTAL AROMATASE COMPLEXED WITH BREAST CANCER DRUG EXEMESTANE | CYTOCHROME P450, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4hoe:A (LYS161) to (TYR186) CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 5- [3-(2,5-DIMETHOXY-4-PHENYLPHENYL)BUT-1-YN-1-YL]-6-METHYLPYRIMIDINE-2, 4-DIAMINE (UCP111E) | ANTIFUNGAL AGENTS, CANDIDA ALBICANS, DRUG DESIGN, ENZYME INHIBITORS, FUNGAL PROTEINS, STRUCTURE-ACTIVITY RELATIONSHIP, TETRAHYDROFOLATE DEHYDROGENASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4x7i:A (GLY334) to (VAL356) CRYSTAL STRUCTURE OF BACE WITH AMINO THIAZINE INHIBITOR LY2886721 | BACE, BETA-SECRETASE, INHIBITOR, COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1oen:A (SER98) to (GLU140) PHOSPHOENOLPYRUVATE CARBOXYKINASE | P-LOOP, NUCLEOTIDE-TRIPHOSPHATE HYDROLASE, KINASE
4hzt:A (GLY395) to (VAL417) STRUCTURE-BASED DESIGN OF NOVEL DIHYDROISOQUINOLINE BACE-1 INHIBITORS THAT DO NOT ENGAGE THE CATALYTIC ASPARTATES | ASPARTIC PROTEASE, HYDROLYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4i4g:A (MET445) to (SER495) CRYSTAL STRUCTURE OF CYP3A4 LIGATED TO OXAZOLE-SUBSTITUTED DESOXYRITONAVIR | MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, CYTOCHROME B5, ENDOPLASMIC RETICULUM, CYTOCHROME P450, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3sn5:A (ARG447) to (PHE501) CRYSTAL STRUCTURE OF HUMAN CYP7A1 IN COMPLEX WITH CHOLEST-4-EN-3-ONE | CYTOCHROME P450, CHOLESTEROL 7-ALPHA HYDROXYLASE, CYP7A1, CHOLEST-4- EN-3-ONE, BILE ACID BIOSYNTHESIS, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE
3sn5:B (ARG447) to (HIS503) CRYSTAL STRUCTURE OF HUMAN CYP7A1 IN COMPLEX WITH CHOLEST-4-EN-3-ONE | CYTOCHROME P450, CHOLESTEROL 7-ALPHA HYDROXYLASE, CYP7A1, CHOLEST-4- EN-3-ONE, BILE ACID BIOSYNTHESIS, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE
1cku:A (ASP11) to (ALA78) AB INITIO SOLUTION AND REFINEMENT OF TWO HIGH POTENTIAL IRON PROTEIN STRUCTURES AT ATOMIC RESOLUTION | ELECTRON TRANSFER PROTEIN, ATOMIC RESOLUTION, DIRECT METHODS, IRON-SULPHUR CLUSTER, METALLOPROTEIN
1cku:B (ASP11) to (ALA78) AB INITIO SOLUTION AND REFINEMENT OF TWO HIGH POTENTIAL IRON PROTEIN STRUCTURES AT ATOMIC RESOLUTION | ELECTRON TRANSFER PROTEIN, ATOMIC RESOLUTION, DIRECT METHODS, IRON-SULPHUR CLUSTER, METALLOPROTEIN
4i8o:B (GLY278) to (LEU292) CRYSTAL STRUCTURE OF THE TOXIN RNLA FROM ESCHERICHIA COLI | TOXIN PROTEIN, TOXIN
2cal:A (THR1011) to (SER1034) CRYSTAL STRUCTURE OF HIS143MET RUSTICYANIN | RUSTICYANIN, IRON RESPIRATORY ELECTRON TRANSPORT CHAIN, BLUE COPPER PROTEIN, ELECTRON TRANSPORT, METAL- BINDING, PERIPLASMIC, TRANSPORT
3g1q:A (GLY424) to (ARG475) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN LIGAND FREE STATE | STEROL 14-ALPHA DEMETHYLASE, CYP51, CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, MEMBRANE PROTEIN, STEROL BIOSYNTHESIS
3g1q:B (GLY424) to (ARG475) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN LIGAND FREE STATE | STEROL 14-ALPHA DEMETHYLASE, CYP51, CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, MEMBRANE PROTEIN, STEROL BIOSYNTHESIS
2ch4:B (LYS418) to (ASP450) COMPLEX BETWEEN BACTERIAL CHEMOTAXIS HISTIDINE KINASE CHEA DOMAINS P4 AND P5 AND RECEPTOR-ADAPTOR PROTEIN CHEW | TRANSFERASE/CHEMOTAXIS, CHEMOTAXIS, PROTEIN-PROTEIN COMPLEX, SIGNAL TRANSDUCTION, HISTIDINE KINASE, SENSORY TRANSDUCTION, PHOSPHORYLATION, TRANSFERASE
4xqk:A (GLU48) to (LYS84) ATP-DEPENDENT TYPE ISP RESTRICTION-MODIFICATION ENZYME LLABIII BOUND TO DNA | ATP-DEPENDENT RESTRICTION-MODIFICATION ENZYME, TYPE ISP RESTRICTION- MODIFICATION ENZYME, ATPASE, HYDROLASE-DNA COMPLEX
4xqk:B (GLU48) to (LYS84) ATP-DEPENDENT TYPE ISP RESTRICTION-MODIFICATION ENZYME LLABIII BOUND TO DNA | ATP-DEPENDENT RESTRICTION-MODIFICATION ENZYME, TYPE ISP RESTRICTION- MODIFICATION ENZYME, ATPASE, HYDROLASE-DNA COMPLEX
2cib:A (ALA397) to (ARG447) HIGH THROUGHPUT SCREENING AND X-RAY CRYSTALLOGRAPHY ASSISTED EVALUATION OF SMALL MOLECULE SCAFFOLDS FOR CYP51 INHIBITORS | HEME, HEME LIPID SYNTHESIS, METAL-BINDING, MONOOXYGENASE, NADP, OXIDOREDUCTASE, PROTEIN-INHIBITOR COMPLEX, STEROID BIOSYNTHESIS, STEROL BIOSYNTHESIS
3g5n:B (GLY438) to (ALA490) TRIPLE LIGAND OCCUPANCY CRYSTAL STRUCTURE OF CYTOCHROME P450 2B4 IN COMPLEX WITH THE INHIBITOR 1-BIPHENYL-4-METHYL-1H-IMIDAZOLE | P450, CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2, ENDOPLASMIC RETICULUM, HEME, IRON, MEMBRANE, METAL-BINDING, MICROSOME, PHOSPHOPROTEIN, POLYMORPHISM
3g5n:D (GLY438) to (ALA490) TRIPLE LIGAND OCCUPANCY CRYSTAL STRUCTURE OF CYTOCHROME P450 2B4 IN COMPLEX WITH THE INHIBITOR 1-BIPHENYL-4-METHYL-1H-IMIDAZOLE | P450, CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4, CYP LM2, ENDOPLASMIC RETICULUM, HEME, IRON, MEMBRANE, METAL-BINDING, MICROSOME, PHOSPHOPROTEIN, POLYMORPHISM
1dd1:A (TYR412) to (LYS436) CRYSTAL STRUCTURE ANALYSIS OF THE SMAD4 ACTIVE FRAGMENT | B-SHEET SANDWICH HELIX-TURN-HELIX, SIGNALING PROTEIN
1dev:A (SER359) to (LYS383) CRYSTAL STRUCTURE OF SMAD2 MH2 DOMAIN BOUND TO THE SMAD- BINDING DOMAIN OF SARA | BETA SHEET, THREE-HELIX BUNDLE, SIGNALING PROTEIN
2cl2:A (GLY176) to (PRO202) ENDO-1,3(4)-BETA-GLUCANASE FROM PHANEROCHAETE CHRYSOSPORIUM, SOLVED USING NATIVE SULFUR SAD, EXHIBITING INTACT HEPTASACCHARIDE GLYCOSYLATION | GLYCOSYL HYDROLASE, GH16, FAMILY 16, LAMINARINASE, LAMINARIN, BETA-GLUCANASE, BASIDIOMYCETE, WHITE ROT FUNGUS, GH7, BETA-1, 3/1, 6-GLUCAN, LAM16A, PICHEA PASTORIS, EXTRACELLULAR, BETA SANDWICH, HYDROLASE
2qjt:A (THR260) to (VAL293) CRYSTAL STRUCTURE OF A BIFUNCTIONAL NMN ADENYLYLTRANSFERASE/ADP RIBOSE PYROPHOSPHATASE COMPLEXED WITH AMP AND MN ION FROM FRANCISELLA TULARENSIS | TWO INDIVIDUAL DOMAINS, TRANSFERASE, HYDROLASE
4iof:A (ASN125) to (VAL153) CRYSTAL STRUCTURE ANALYSIS OF FAB-BOUND HUMAN INSULIN DEGRADING ENZYME (IDE) | HYDROLASE, ZINC METALLOPROTEASE
3ghy:A (ALA34) to (HIS61) CRYSTAL STRUCTURE OF A PUTATIVE KETOPANTOATE REDUCTASE FROM RALSTONIA SOLANACEARUM MOLK2 | OXIDOREDUCTASE, NAD-BINDING DOMAIN, PSI-2, NYSGXRC, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3gmj:D (SER347) to (LYS371) CRYSTAL STRUCTURE OF MAD MH2 DOMAIN | MH2,SMAD,MAD, CYTOPLASM, DEVELOPMENTAL PROTEIN, NUCLEUS, PHOSPHOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, UBL CONJUGATION
3gmj:B (SER347) to (LYS371) CRYSTAL STRUCTURE OF MAD MH2 DOMAIN | MH2,SMAD,MAD, CYTOPLASM, DEVELOPMENTAL PROTEIN, NUCLEUS, PHOSPHOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, UBL CONJUGATION
4y37:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH FRAGEMENT 305 | FRAGMENT SCREENING, HYDROLASE, INHIBITION
4y3d:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH FRAGMENT 321 | FRAGMENT SCREENING, ASPARTIC PROTEASE, INHIBITION, HYDROLASE
4y3n:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH FRAGMENT 273 | FRAGMENT SCREENING, ASPARTIC PROTEASE, INHIBITION, HYDROLASE
4y45:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH FRAGMENT 291 | FRAGMENT SCREENING, HYDROLASE, INHIBITION
4y47:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH FRAGMENT 162 | FRAGMENT SCREENING, HYDROLASE, INHIBITION
2qzw:A (GLY307) to (GLN329) SECRETED ASPARTIC PROTEINASE (SAP) 1 FROM CANDIDA ALBICANS | ASPARTIC PROTEINASE, CANDIDA ALBICANS, ASPARTYL PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, GLYCOPROTEIN, HYDROLASE, PROTEASE, SECRETED, ZYMOGEN
2qzw:B (GLY307) to (GLN329) SECRETED ASPARTIC PROTEINASE (SAP) 1 FROM CANDIDA ALBICANS | ASPARTIC PROTEINASE, CANDIDA ALBICANS, ASPARTYL PROTEASE, CLEAVAGE ON PAIR OF BASIC RESIDUES, GLYCOPROTEIN, HYDROLASE, PROTEASE, SECRETED, ZYMOGEN
4y4b:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH FRAGMENT 323 | FRAGMENT SCREENING, HYDROLASE, INHIBITION
4y4e:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH FRAGMENT 131 | FRAGMENT SCREENING, HYDROLASE, INHIBITION
4j2k:B (PRO84) to (LYS109) CRYSTAL STRUCTURE OF A PLANT TRYPSIN INHIBITOR ECTI | TREFOIL, SERINE PROTEASE INHIBITOR, HYDROLASE INHIBITOR
4j2y:A (PRO84) to (LYS109) CRYSTAL STRUCTURE OF A PLANT TRYPSIN INHIBITOR ECTI IN COMPLEX WITH BOVINE TRYPSIN. | TREFOIL, SERINE PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4y54:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH FRAGMENT 56 | FRAGMENT SCREENING, HYDROLASE, INHIBITION
4y58:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH FRAGMENT 260 | FRAGMENT SCREENING, ASPARTIC PROTEASE, INHIBITION, HYDROLASE
4y5g:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH FRAGMENT 272 | FRAGMENT SCREENING, ASPARTIC PROTEASE, INHIBITION, HYDROLASE
2r5w:A (THR260) to (VAL293) CRYSTAL STRUCTURE OF A BIFUNCTIONAL NMN ADENYLYLTRANSFERASE/ADP RIBOSE PYROPHOSPHATASE FROM FRANCISELLA TULARENSIS | TWO DOMAIN PROTEIN, NUCLEOTIDYLTRANSFERASE, HYDROLASE, TRANSFERASE
1e9x:A (ALA397) to (ARG447) CYTOCHROME P450 14 ALPHA-STEROL DEMETHYLASE (CYP51) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 4-PHENYLIMIDAZOLE | OXIDOREDUCTASE, CYTOCHROME P450, 14 ALPHA-STEROL DEMETHYLASE, AZOLE INHIBITORS
3gtn:A (ASP189) to (MET227) CRYSTAL STRUCTURE OF XYNC FROM BACILLUS SUBTILIS 168 | XYLANASE, GLYCOSYL HYDROLASE FAMILY 5, GH5, GH 5, XYNC, BACILLUS SUBTILIS, GLUCURONOXYLAN, GLYCOSYL HYDROLASE, CARBOHYDRATE METABOLISM, GLYCOSIDASE, HYDROLASE, POLYSACCHARIDE DEGRADATION, SECRETED, XYLAN DEGRADATION
3gtn:B (ASP189) to (MET227) CRYSTAL STRUCTURE OF XYNC FROM BACILLUS SUBTILIS 168 | XYLANASE, GLYCOSYL HYDROLASE FAMILY 5, GH5, GH 5, XYNC, BACILLUS SUBTILIS, GLUCURONOXYLAN, GLYCOSYL HYDROLASE, CARBOHYDRATE METABOLISM, GLYCOSIDASE, HYDROLASE, POLYSACCHARIDE DEGRADATION, SECRETED, XYLAN DEGRADATION
1ea1:A (GLY396) to (ARG447) CYTOCHROME P450 14 ALPHA-STEROL DEMETHYLASE (CYP51) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH FLUCONAZOLE | OXIDOREDUCTASE, CYTOCHROME P450, 14 ALPHA-STEROL DEMETHYLASE, AZOLE INHIBITORS
1eag:A (GLY307) to (GLN329) SECRETED ASPARTIC PROTEINASE (SAP2) FROM CANDIDA ALBICANS COMPLEXED WITH A70450 | SAP2, CANDIDA ALBICANS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, ASPARTIC PROTEASE
3tik:B (GLY424) to (ARG475) STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH THE TIPIFARNIB DERIVATIVE 6-((4-CHLOROPHENYL)(METHOXY)(1-METHYL- 1H-IMIDAZOL-5-YL)METHYL)-4-(2,6-DIFLUOROPHENYL)-1-METHYLQUINOLIN- 2(1H)-ONE | STEROL 14-ALPHA DEMETHYLASE, CYP51, HEME, MONOOXYGENASE, STEROL BIOSYNTHESIS, CYTOCHROME P450 FOLD, OXIDOREDUCTASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM MEMBRANE
3tik:D (GLY424) to (ARG475) STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH THE TIPIFARNIB DERIVATIVE 6-((4-CHLOROPHENYL)(METHOXY)(1-METHYL- 1H-IMIDAZOL-5-YL)METHYL)-4-(2,6-DIFLUOROPHENYL)-1-METHYLQUINOLIN- 2(1H)-ONE | STEROL 14-ALPHA DEMETHYLASE, CYP51, HEME, MONOOXYGENASE, STEROL BIOSYNTHESIS, CYTOCHROME P450 FOLD, OXIDOREDUCTASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM MEMBRANE
1ebu:A (ASP306) to (GLY336) HOMOSERINE DEHYDROGENASE COMPLEX WITH NAD ANALOGUE AND L- HOMOSERINE | HOMOSERINE, DEHYDROGENASE, DINUCLEOTIDE, TERNARY, ANALOGUE, OXIDOREDUCTASE
1eed:P (GLY303) to (SER325) X-RAY CRYSTALLOGRAPHIC ANALYSIS OF INHIBITION OF ENDOTHIAPEPSIN BY CYCLOHEXYL RENIN INHIBITORS | ASPARTIC PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3gw9:B (GLY424) to (ARG475) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI BOUND TO AN INHIBITOR N-(1-(2,4- DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3, 4-OXAZIAZOL-2-YL)BENZAMIDE | STEROL 14ALPHA-DEMETHYLASE, CYP51, CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, LIPIDS, ENDOPLASMIC RETICULUM, IRON, HEME-THIOLATE PROTEIN
3gw9:C (GLY424) to (ARG475) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI BOUND TO AN INHIBITOR N-(1-(2,4- DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3, 4-OXAZIAZOL-2-YL)BENZAMIDE | STEROL 14ALPHA-DEMETHYLASE, CYP51, CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, LIPIDS, ENDOPLASMIC RETICULUM, IRON, HEME-THIOLATE PROTEIN
3gw9:D (GLY424) to (ARG475) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI BOUND TO AN INHIBITOR N-(1-(2,4- DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3, 4-OXAZIAZOL-2-YL)BENZAMIDE | STEROL 14ALPHA-DEMETHYLASE, CYP51, CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, LIPIDS, ENDOPLASMIC RETICULUM, IRON, HEME-THIOLATE PROTEIN
3gwm:A (GLY99) to (GLU129) CRYSTAL STRUCTURE OF THE HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE (ACPS) FROM MYCOBACTERIUM SMEGMATIS | HOMO-TRIMER, 9-STAND PSEUDO BETA BARREL PROTEIN, CYTOPLASM, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS, MAGNESIUM, METAL- BINDING, TRANSFERASE
3tmz:A (GLU439) to (ALA490) CRYSTAL STRUCTURE OF P450 2B4(H226Y) IN COMPLEX WITH AMLODIPINE | P450, CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, MEMBRANE PROTEIN, CYP 2B4,
4ybf:A (GLY300) to (GLN322) ASPARTIC PROTEINASE SAPP2 SECRETED FROM CANDIDA PARAPSILOSIS AT 1.25 A RESOLUTION | ASPARTIC PROTEINASE SAPP2, HYDROLASE
3tqs:A (GLY151) to (PRO189) STRUCTURE OF THE DIMETHYLADENOSINE TRANSFERASE (KSGA) FROM COXIELLA BURNETII | PROTEIN SYNTHESIS, TRANSFERASE
3tqs:B (GLY151) to (PRO189) STRUCTURE OF THE DIMETHYLADENOSINE TRANSFERASE (KSGA) FROM COXIELLA BURNETII | PROTEIN SYNTHESIS, TRANSFERASE
3tqs:C (GLY151) to (PRO189) STRUCTURE OF THE DIMETHYLADENOSINE TRANSFERASE (KSGA) FROM COXIELLA BURNETII | PROTEIN SYNTHESIS, TRANSFERASE
3tqs:D (GLY151) to (PRO189) STRUCTURE OF THE DIMETHYLADENOSINE TRANSFERASE (KSGA) FROM COXIELLA BURNETII | PROTEIN SYNTHESIS, TRANSFERASE
4ydq:A (GLY602) to (ASN623) CRYSTAL STRUCTURE OF PROLYL-TRNA SYNTHETASE (PRS) FROM PLASMODIUM FALCIPARUM IN COMPLEX WITH HALOFUGINONE AND AMPPNP | PROLYL-TRNA SYNTHETASE, COMPLEX, HALOFUGINONE, MALARIA
1epl:E (GLY303) to (SER325) A STRUCTURAL COMPARISON OF 21 INHIBITOR COMPLEXES OF THE ASPARTIC PROTEINASE FROM ENDOTHIA PARASITICA | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1epn:E (GLY303) to (SER325) A STRUCTURAL COMPARISON OF 21 INHIBITOR COMPLEXES OF THE ASPARTIC PROTEINASE FROM ENDOTHIA PARASITICA | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1er8:E (GLY303) to (SER325) THE ACTIVE SITE OF ASPARTIC PROTEINASES | HYDROLASE, ACID PROTEINASE
4jlt:A (GLU439) to (HIS492) CRYSTAL STRUCTURE OF P450 2B4(H226Y) IN COMPLEX WITH PAROXETINE | P450, CYTOCHROME P450 2B4, MONOOXYGENASE, OXIDOREDUCTASE, ME PROTEIN, CYP 2B4
4jp9:A (GLY382) to (VAL404) SPIROCYCLIC BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1 (BACE1) INHIBITORS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4jpc:A (GLY382) to (VAL404) SPIROCYCLIC BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1 (BACE1) INHIBITORS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4jpe:A (GLY382) to (VAL404) SPIROCYCLIC BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1 (BACE1) INHIBITORS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1eyt:A (ASP11) to (ALA76) CRYSTAL STRUCTURE OF HIGH-POTENTIAL IRON-SULFUR PROTEIN FROM THERMOCHROMATIUM TEPIDUM | IRON-SULFUR PROTEIN, ELECTRON TRANSPORT
2uuq:A (ALA357) to (THR404) CRYSTAL STRUCTURE OF CYP130 FROM MYCOBACTERIUM TUBERCULOSIS IN THE LIGAND-FREE FORM | P450, IRON, HEME, MONOOXYGENASE, METAL-BINDING, OXIDOREDUCTASE, HYPOTHETICAL PROTEIN
2uvn:B (GLY356) to (VAL403) CRYSTAL STRUCTURE OF ECONAZOLE-BOUND CYP130 FROM MYCOBACTERIUM TUBERCULOSIS | IRON, HEME, MONOOXYGENASE, METAL-BINDING, OXIDOREDUCTASE
1fah:A (GLY402) to (SER450) STRUCTURE OF CYTOCHROME P450 | MONOOXYGENASE, ELECTRON TRANSPORT, HEME
2uwh:A (GLY402) to (SER450) CYTOCHROME P450 BM3 MUTANT IN COMPLEX WITH PALMITIC ACID | FATTY-ACID BINDING, MULTIFUNCTIONAL ENZYME, METAL-BINDING, OXIDOREDUCTASE, ELECTRON TRANSPORT, TRANSPORT, HYDROXYLASE, FLAVOPROTEIN, MONOOXYGENASE, FMN, FAD, NADP, IRON, HEME, REDOX, MEMBRANE, CYTOCHROME P450 BM3 MUTANT
2v0m:A (GLY444) to (SER495) CRYSTAL STRUCTURE OF HUMAN P450 3A4 IN COMPLEX WITH KETOCONAZOLE | METAL-BINDING, TRANSMEMBRANE, OXIDOREDUCTASE, ENDOPLASMIC RETICULUM, DRUG METABOLIZING ENZYME, KETOCONAZOL, POLYMORPHISM, MONOOXYGENASE, P450, NADP, IRON, HEME, CYP3A4, MEMBRANE, MICROSOME
2v0m:D (MET445) to (SER495) CRYSTAL STRUCTURE OF HUMAN P450 3A4 IN COMPLEX WITH KETOCONAZOLE | METAL-BINDING, TRANSMEMBRANE, OXIDOREDUCTASE, ENDOPLASMIC RETICULUM, DRUG METABOLIZING ENZYME, KETOCONAZOL, POLYMORPHISM, MONOOXYGENASE, P450, NADP, IRON, HEME, CYP3A4, MEMBRANE, MICROSOME
2v0s:A (SER208) to (ARG236) CRYSTAL STRUCTURE OF A HAIRPIN EXCHANGE VARIANT (LR1) OF THE TARGETING LINE-1 RETROTRANSPOSON ENDONUCLEASE | TRANSCRIPTION, APE-1 TYPE, ENDONUCLEASE, RETROTRANSPOSITION, RETROTRANSPOSON, PROTEIN ENGINEERING, HYPOTHETICAL PROTEIN
1r62:A (LEU314) to (PRO346) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE TWO-COMPONENT SYSTEM TRANSMITTER PROTEIN NRII (NTRB) | NRII, PII, HISTIDINE KINASE, TWO COMPONENT SYSTEM, TRANSFERASE
2er0:E (GLY303) to (SER325) X-RAY STUDIES OF ASPARTIC PROTEINASE-STATINE INHIBITOR COMPLEXES | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2er6:E (GLY303) to (SER325) THE STRUCTURE OF A SYNTHETIC PEPSIN INHIBITOR COMPLEXED WITH ENDOTHIAPEPSIN. | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, ACID PROTEINASE
2er7:E (GLY303) to (SER325) X-RAY ANALYSES OF ASPARTIC PROTEINASES.III. THREE-DIMENSIONAL STRUCTURE OF ENDOTHIAPEPSIN COMPLEXED WITH A TRANSITION-STATE ISOSTERE INHIBITOR OF RENIN AT 1.6 ANGSTROMS RESOLUTION | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, ACID PROTEINASE
3hip:A (ASP111) to (ALA176) HIGH-POTENTIAL IRON-SULFUR PROTEIN FROM CHROMATIUM PURPURATUM | ELECTRON TRANSFER, PHOTOSYNTHESIS, METALLOPROTEIN
3hip:B (ASP111) to (ALA176) HIGH-POTENTIAL IRON-SULFUR PROTEIN FROM CHROMATIUM PURPURATUM | ELECTRON TRANSFER, PHOTOSYNTHESIS, METALLOPROTEIN
3hip:C (ASP111) to (ALA176) HIGH-POTENTIAL IRON-SULFUR PROTEIN FROM CHROMATIUM PURPURATUM | ELECTRON TRANSFER, PHOTOSYNTHESIS, METALLOPROTEIN
3udj:A (GLY334) to (VAL356) CRYSTAL STRUCTURE OF BACE WITH COMPOUND 5 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3udk:A (GLY334) to (VAL356) CRYSTAL STRUCTURE OF BACE WITH COMPOUND 6 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3udm:A (GLY334) to (VAL356) CRYSTAL STRUCTURE OF BACE WITH COMPOUND 8 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3udn:A (GLY334) to (VAL356) CRYSTAL STRUCTURE OF BACE WITH COMPOUND 9 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3udy:A (GLY334) to (VAL356) CRYSTAL STRUCTURE OF BACE WITH COMPOUND 11 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ug9:A (SER280) to (LEU338) CRYSTAL STRUCTURE OF THE CLOSED STATE OF CHANNELRHODOPSIN | MICROBIALRHODOPSIN, SEVEN-TRANSMEMBRANE, LIGHT-GATED CATION CHANNEL, MEMBRANE PROTEIN
4k9x:A (MET445) to (SER495) COMPLEX OF HUMAN CYP3A4 WITH A DESOXYRITONAVIR ANALOG | CYTOCHROME P450 3A4, ALPHA-BETA PROTEIN, CYTOCHROME P450 FOLD, MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
2vbl:A (ASN6) to (LYS48) MOLECULAR BASIS OF HUMAN XPC GENE RECOGNITION AND CLEAVAGE BY ENGINEERED HOMING ENDONUCLEASE HETERODIMERS | UV-INDUCED DNA DAMAGE, CUTTING DNA ENDONUCLEASES, PLASTID, NUCLEASE, HYDROLASE, CHLOROPLAST, ENDONUCLEASE, INTRON HOMING, AMEL3- 4_MAGNESIUM, DOUBLE STRAND BREAK (DSB), HOMING ENDONUCLEASES (HES)
4ke1:A (GLY334) to (VAL356) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH HYDROXYETHYLAMINE- MACROCYCLIC INHIBITOR 19 | ALZHEIMER'S DISEASE, ASPARTIC PROTEASE, AMYLOID PRECURSOR PROTEIN (APP), HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3une:S (HIS20) to (GLN53) MOUSE CONSTITUTIVE 20S PROTEASOME | 20S PROTEASOME COMPRISES 28 SUBUNITS, PROTEASE, CYTOSOL, HYDROLASE
2ve3:B (GLY393) to (SER442) RETINOIC ACID BOUND CYANOBACTERIAL CYP120A1 | OXIDOREDUCTASE, MONOOXYGENASE, METAL-BINDING, HEME, IRON
2ffs:B (ARG22) to (PRO63) STRUCTURE OF PR10-ALLERGEN-LIKE PROTEIN PA1206 FROM PSEUDOMONAS AERUGINOSA PAO1 | 7-STRANDED BETA SHEET, C-TERMINAL HELIX, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
2fge:B (THR610) to (LYS649) CRYSTAL STRUCTURE OF PRESEQUENCE PROTEASE PREP FROM ARABIDOPSIS THALIANA | PEPTIDASOME; PROTEASE-PEPTIDE COMPLEX, HYDROLASE, PLANT PROTEIN
3uri:A (GLY305) to (SER328) ENDOTHIAPEPSIN-DB5 COMPLEX. | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, ASPARTIC PROTEINASE MECHANISM, TRANSITION STATE ANALOGUE.
3url:A (GLY305) to (SER328) ENDOTHIAPEPSIN-DB6 COMPLEX. | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, ASPARTIC PROTEINASE MECHANISM, TRANSITION STATE ANALOGUE.
2fla:A (ASP11) to (ALA76) STRUCTURE OF THEREDUCED HIPIP FROM THERMOCHROMATIUM TEPIDUM AT 0.95 ANGSTROM RESOLUTION | IRON-SULFUR PROTEIN, ELECTRON TRANSPORT
4zad:A (HIS348) to (LYS372) STRUCTURE OF C. DUBLIENSIS FDC1 WITH THE PRENYLATED-FLAVIN COFACTOR IN THE IMINIUM FORM. | (DE)CARBOXYLASE, PRENYLATED FLAVIN BINDING, UBID-TYPE ENZYME, LYASE
4zad:B (HIS348) to (LYS372) STRUCTURE OF C. DUBLIENSIS FDC1 WITH THE PRENYLATED-FLAVIN COFACTOR IN THE IMINIUM FORM. | (DE)CARBOXYLASE, PRENYLATED FLAVIN BINDING, UBID-TYPE ENZYME, LYASE
1s98:A (ASP65) to (ASN92) E.COLI ISCA CRYSTAL STRUCTURE TO 2.3 A | ISCA, FE-S CLUSTER, IRON, SULFUR, ISC, METAL TRANSPORT
4zfa:A (GLY402) to (LYS452) CYTOCHROME P450 WILD TYPE FROM BM3 WITH BOUND PEG | CYTOCHROME P450, HEME OXIDASE DOMAIN, OXIDOREDUCTASE, BACILLUS MEGATERIUM
4zfb:A (GLY402) to (LYS452) CYTOCHROME P450 PENTAMUTANT FROM BM3 BOUND TO PALMITIC ACID | CYTOCHROME P450, HEME OXIDASE DOMAIN, OXIDOREDUCTASE, BACILLUS MEGATERIUM
4kpa:A (GLY402) to (SER450) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM-3 IN COMPLEX WITH N- PALMITOYLGLYCINE (NPG) | HEME-DEPENDENT STEREOSPECIFIC OXIDATION OF SUBSTRATES, OXIDOREDUCTASE
2g27:B (GLY309) to (LEU331) KETOPIPERAZINE-BASED RENIN INHIBITORS: OPTIMIZATION OF THE "C" RING | PROTEIN-LIGAND COMPLEXES, HYDROLASE
2ga0:C (ALA42) to (THR86) VARIABLE SMALL PROTEIN 1 OF BORRELIA TURICATAE (VSPA OR VSP1) | HELICAL BUNDLE, NI(II) BINDING SITES, IMMUNE SYSTEM
2ga0:E (ALA42) to (THR86) VARIABLE SMALL PROTEIN 1 OF BORRELIA TURICATAE (VSPA OR VSP1) | HELICAL BUNDLE, NI(II) BINDING SITES, IMMUNE SYSTEM
2gdv:B (THR124) to (SER155) SUCROSE PHOSPHORYLASE FROM BIFIDOBACTERIUM ADOLESCENTIS REACTED WITH SUCROSE | BETA-ALPHA-BARRELS, DIMER, GLYCOSIDE HYDROLASE, TRANSFERASE
2vzn:A (TRP168) to (TYR196) CRYSTAL STRUCTURE OF THE MAJOR ALLERGEN FROM FIRE ANT VENOM, SOL I 3 | MAJOR FIRE ANT ALLERGEN, SOL I 3, SECRETED, ALLERGEN, CROSS- REACTIVITY
2glu:A (SER196) to (LYS227) THE CRYSTAL STRUCTURE OF YCGJ PROTEIN FROM BACILLUS SUBITILIS | NYSGXRC, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, UNKNOWN FUNCTION
1h4t:A (PRO352) to (THR371) PROLYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH L-PROLINE | AMINOACYL-TRNA SYNTHETASE, ATP + L-PROLINE + TRNA(PRO) AMP + PPI + L-PROLYL-TRNA(PRO), CLASS II AMINOACYL-TRNA SYNTHETASE
1h4t:C (PRO352) to (THR371) PROLYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH L-PROLINE | AMINOACYL-TRNA SYNTHETASE, ATP + L-PROLINE + TRNA(PRO) AMP + PPI + L-PROLYL-TRNA(PRO), CLASS II AMINOACYL-TRNA SYNTHETASE
1h4v:B (GLY385) to (ARG406) HISTIDYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS (LIGAND FREE) | TRNA SYNTHETASE, CLASS IIA AMINOACYL-TRNA SYNTHETASE, ATP + L-HISTIDINE TRNA(HIS)-> AMP + PPI + L-HISTIDYL-TRNA(HIS)
1h54:A (GLY677) to (PRO700) MALTOSE PHOSPHORYLASE FROM LACTOBACILLUS BREVIS | HYDROLASE, MALTOSE METABOLISM
3iec:D (PHE156) to (GLU199) HELICOBACTER PYLORI CAGA INHIBITS PAR1/MARK FAMILY KINASES BY MIMICKING HOST SUBSTRATES | PROTEIN-PROTEIN COMPLEX, KINASE, VIRULENCE FACTOR, ALTERNATIVE PROMOTER USAGE, ATP-BINDING, CELL MEMBRANE, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, MAGNESIUM, MEMBRANE, METAL-BINDING, NUCLEOTIDE- BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, SIGNALING PROTEIN-TOXIN COMPLEX
2w0a:A (ALA397) to (ARG447) CYP51 OF M. TUBERCULOSIS BOUND TO AN INHIBITOR N-[(1S)-2-METHYL-1-(PYRIDIN-4-YLCARBAMOYL)PROPYL] CYCLOHEXANECARBOXAMIDE | STEROID BIOSYNTHESIS, PROTEIN-INHIBITOR COMPLEX, METAL-BINDING, OXIDOREDUCTASE, LIPID SYNTHESIS, NADP, IRON, HEME, CYTOPLASM, MONOOXYGENASE, X-RAY DIFFRACTION, STEROL BIOSYNTHESIS
4lap:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH THIOPHEN-BASED INHIBITOR SAP114 | ASPARTATE PROTEASE, INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1tje:A (GLY28) to (THR61) CRYSTAL STRUCTURE OF THE EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE | LIGASE
1tke:A (GLY28) to (THR61) CRYSTAL STRUCTURE OF THE EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE COMPLEXED WITH SERINE | LIGASE
1tkg:A (GLY28) to (THR61) CRYSTAL STRUCTURE OF THE EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE COMPLEXED WITH AN ANALOG OF SERYLADENYLATE | LIGASE
1tky:A (GLY28) to (THR61) CRYSTAL STRUCTURE OF THE EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE COMPLEXED WITH SERYL-3'-AMINOADENOSINE | LIGASE
2h6t:A (GLY307) to (GLN329) SECRETED ASPARTIC PROTEINASE (SAP) 3 FROM CANDIDA ALBICANS COMPLEXED WITH PEPSTATIN A | ASPARTIC PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1hlq:A (ASP9) to (SER69) CRYSTAL STRUCTURE OF RHODOFERAX FERMENTANS HIGH POTENTIAL IRON-SULFUR PROTEIN REFINED TO 1.45 A | IRON SULFUR CLUSTER, ELECTRON TRANSPORT
1hlq:B (ASP9) to (SER69) CRYSTAL STRUCTURE OF RHODOFERAX FERMENTANS HIGH POTENTIAL IRON-SULFUR PROTEIN REFINED TO 1.45 A | IRON SULFUR CLUSTER, ELECTRON TRANSPORT
1hlq:C (ASP9) to (SER69) CRYSTAL STRUCTURE OF RHODOFERAX FERMENTANS HIGH POTENTIAL IRON-SULFUR PROTEIN REFINED TO 1.45 A | IRON SULFUR CLUSTER, ELECTRON TRANSPORT
2hcv:C (PRO55) to (THR72) CRYSTAL STRUCTURE OF L-RHAMNOSE ISOMERASE FROM PSEUDOMONAS STUTZERI WITH METAL ION | BETA/ALPHA BARREL, TIM BARREL, HOMO-TETRAMER, METAL-BINDING PROTEIN, ISOMERASE
1hpi:A (ASP8) to (THR66) MOLECULAR STRUCTURE OF THE OXIDIZED HIGH-POTENTIAL IRON- SULFUR PROTEIN ISOLATED FROM ECTOTHIORHODOSPIRA VACUOLATA | ELECTRON TRANSFER(IRON-SULFUR PROTEIN)
1hrr:A (ASP11) to (ALA78) THE THREE DIMENSIONAL STRUCTURE OF THE REDUCED HIGH POTENTIAL IRON-SULFUR PROTEIN FROM CHROMATIUM VINOSUM THROUGH NMR | ELECTRON TRANSFER (IRON-SULFUR)
2wgy:A (ALA357) to (THR404) CRYSTAL STRUCTURE OF THE G243A MUTANT OF CYP130 FROM M. TUBERCULOSIS | COMPLETE PROTEOME, HEME, HYPOTHETICAL PROTEIN, IRON, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE
2hi4:A (GLU461) to (ARG511) CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 1A2 IN COMPLEX WITH ALPHA-NAPHTHOFLAVONE | CYP1A2, P450 1A2, P450, MONOOXYGENASE, DRUG METABOLIZING ENZYME, ALPHA-NAPHTHOFLAVONE, BENZO(H)FLAVONE, 7,8- BENZOFLAVONE, OXIDOREDUCTASE, HEME
2wh8:A (ALA357) to (VAL403) INTERACTION OF MYCOBACTERIUM TUBERCULOSIS CYP130 WITH HETEROCYCLIC ARYLAMINES | IRON, HEME, MONOOXYGENASE, METAL-BINDING, OXIDOREDUCTASE, HYPOTHETICAL PROTEIN, COMPLETE PROTEOME
2whw:B (ALA357) to (ARG406) SELECTIVE OXIDATION OF CARBOLIDE C-H BONDS BY ENGINEERED MACROLIDE P450 MONOOXYGENASE | ANTIBIOTIC BIOSYNTHESIS, CYP107L1, CYTOCHROME P450, HEME, IRON, MACROLIDE MONOOXYGENASE, METAL-BINDING, MONOOXYGENASE, OXIDOREDUCTASE, OXIDOREDUCTASE ANTIBIOTIC BIOSYNTHESIS, PIKC
3iyf:P (LYS288) to (GLY319) ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | GROUP II CHAPERONIN, PROTEIN FOLDING, MM-CPN, SINGLE PARTICLE RECONSTRUCTION, METHANOCOCCUS MARIPALUDIS, CHAPERONE, ATP-BINDING, NUCLEOTIDE-BINDING
2hpd:A (GLY402) to (LYS452) CRYSTAL STRUCTURE OF HEMOPROTEIN DOMAIN OF P450BM-3, A PROTOTYPE FOR MICROSOMAL P450'S | OXIDOREDUCTASE(OXYGENASE)
1i58:A (LYS418) to (ASP450) STRUCTURE OF THE HISTIDINE KINASE CHEA ATP-BINDING DOMAIN IN COMPLEX WITH ATP ANALOG ADPCP AND MAGNESIUM | BETA-ALPHA SANDWICH, SIGNALING PROTEIN, TRANSFERASE
1i58:B (LYS418) to (ASP450) STRUCTURE OF THE HISTIDINE KINASE CHEA ATP-BINDING DOMAIN IN COMPLEX WITH ATP ANALOG ADPCP AND MAGNESIUM | BETA-ALPHA SANDWICH, SIGNALING PROTEIN, TRANSFERASE
1i59:A (LYS418) to (ASP450) STRUCTURE OF THE HISTIDINE KINASE CHEA ATP-BINDING DOMAIN IN COMPLEX WITH ADPNP AND MAGENSIUM | BETA-ALPHA SANDWICH, SIGNALING PROTEIN, TRANSFERASE
1i59:B (LYS418) to (ASP450) STRUCTURE OF THE HISTIDINE KINASE CHEA ATP-BINDING DOMAIN IN COMPLEX WITH ADPNP AND MAGENSIUM | BETA-ALPHA SANDWICH, SIGNALING PROTEIN, TRANSFERASE
1i5a:A (LYS418) to (ASP450) STRUCTURE OF CHEA DOMAIN P4 IN COMPLEX WITH ADPCP AND MANGANESE | BETA-ALPHA SANDWICH, SIGNALING PROTEIN, TRANSFERASE
1i5a:B (LYS418) to (ASP450) STRUCTURE OF CHEA DOMAIN P4 IN COMPLEX WITH ADPCP AND MANGANESE | BETA-ALPHA SANDWICH, SIGNALING PROTEIN, TRANSFERASE
1i5b:A (LYS418) to (ASP450) STRUCTURE OF CHEA DOMAIN P4 IN COMPLEX WITH ADPNP AND MANGANESE | BETA-ALPHA SANDWICH, SIGNALING PROTEIN, TRANSFERASE
1i5b:B (LYS418) to (ASP450) STRUCTURE OF CHEA DOMAIN P4 IN COMPLEX WITH ADPNP AND MANGANESE | BETA-ALPHA SANDWICH, SIGNALING PROTEIN, TRANSFERASE
1i5c:A (LYS418) to (ASP450) STRUCTURE OF CHEA DOMAIN P4 IN COMPLEX WITH ADP | BETA-ALPHA SANDWICH, SIGNALING PROTEIN, TRANSFERASE
1i5c:B (GLU419) to (ASP450) STRUCTURE OF CHEA DOMAIN P4 IN COMPLEX WITH ADP | BETA-ALPHA SANDWICH, SIGNALING PROTEIN, TRANSFERASE
1ia1:A (LYS161) to (TYR186) CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 5-(PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE (GW997) | OXIDOREDUCTASE, ANTIFUNGAL TARGET, REDUCTASE
1ia2:A (LYS161) to (TYR186) CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 5-[(4-METHYLPHENYL)SULFANYL]-2,4- QUINAZOLINEDIAMINE (GW578) | OXIDOREDUCTASE, ANTIFUNGAL TARGET, REDUCTASE
1ia3:A (LYS161) to (TYR186) CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEX IN WHICH THE DIHYDRONICOTINAMIDE MOIETY OF DIHYDRO-NICOTINAMIDE- ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) IS DISPLACED BY 5- [(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE (GW995) | OXIDOREDUCTASE, ANTIFUNGAL TARGET, REDUCTASE, DIHYDRONICOTINAMIDE DISPLACED
2wuz:B (GLY424) to (LYS477) X-RAY STRUCTURE OF CYP51 FROM TRYPANOSOMA CRUZI IN COMPLEX WITH FLUCONAZOLE IN ALTERNATIVE CONFORMATION | OXIDOREDUCTASE, METHYLTRANSFERASE, P450, IRON, CYP51, METAL-BINDING, ERGOSTEROL BIOSYNTHESIS
2wv2:A (GLY424) to (ARG475) X-RAY STRUCTURE OF CYP51 FROM THE HUMAN PATHOGEN TRYPANOSOMA BRUCEI IN COMPLEX WITH FLUCONAZOLE | OXIDOREDUCTASE, METHYLTRANSFERASE, P450, IRON, CYP51, METAL- BINDING, ERGOSTEROL BIOSYNTHESIS
2i4q:B (GLY311) to (LEU333) HUMAN RENIN/PF02342674 COMPLEX | RENIN INHIBITOR, PROTEIN-LIGAND COMPLEX, HYDROLASE
2i57:D (PRO55) to (THR72) CRYSTAL STRUCTURE OF L-RHAMNOSE ISOMERASE FROM PSEUDOMONAS STUTZERI IN COMPLEX WITH D-ALLOSE | BETA/ALPHA BARREL, TIM BARREL, HOMO-TETRAMER, METAL-BINDING PROTEIN, ISOMERASE
3w91:B (ILE6) to (ASP49) CRYSTAL STRUCTURE OF SEMET-LABELED YEAST N-ACETYLTRANSFERASE MPR1 L87M MUTANT | ANTIOXIDANT ENZYME, N-ACETYLTRANSFERASE, TRANSFERASE
2i7h:A (ASN141) to (TYR164) CRYSTAL STRUCTURE OF THE NITROREDUCTASE-LIKE FAMILY PROTEIN FROM BACILLUS CEREUS | ALPHA-BETA, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, OXIDOREDUCTASE
1iq8:A (ALA254) to (ARG270) CRYSTAL STRUCTURE OF ARCHAEOSINE TRNA-GUANINE TRANSGLYCOSYLASE FROM PYROCOCCUS HORIKOSHII | (ALPHA/BETA)8 BARREL, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
2wx2:A (GLY424) to (ARG475) X-RAY STRUCTURE OF CYP51 FROM THE HUMAN PATHOGEN TRYPANOSOMA CRUZI IN COMPLEX WITH FLUCONAZOLE | P450, HEME, IRON, METAL-BINDING, METHYLTRANSFERASE, ERGOSTEROL BIOSYNTHESIS, OXIDOREDUCTASE
2wx2:B (GLN425) to (LYS477) X-RAY STRUCTURE OF CYP51 FROM THE HUMAN PATHOGEN TRYPANOSOMA CRUZI IN COMPLEX WITH FLUCONAZOLE | P450, HEME, IRON, METAL-BINDING, METHYLTRANSFERASE, ERGOSTEROL BIOSYNTHESIS, OXIDOREDUCTASE
3j1e:A (LYS325) to (SER355) CRYO-EM STRUCTURE OF 9-FOLD SYMMETRIC RATCPN-BETA IN APO STATE | GROUP II CHAPERONIN, CHAPERONE
3j1e:N (LYS325) to (SER355) CRYO-EM STRUCTURE OF 9-FOLD SYMMETRIC RATCPN-BETA IN APO STATE | GROUP II CHAPERONIN, CHAPERONE
3j1e:O (LYS325) to (SER355) CRYO-EM STRUCTURE OF 9-FOLD SYMMETRIC RATCPN-BETA IN APO STATE | GROUP II CHAPERONIN, CHAPERONE
3j1e:S (LYS324) to (SER355) CRYO-EM STRUCTURE OF 9-FOLD SYMMETRIC RATCPN-BETA IN APO STATE | GROUP II CHAPERONIN, CHAPERONE
1iru:F (HIS20) to (GLN53) CRYSTAL STRUCTURE OF THE MAMMALIAN 20S PROTEASOME AT 2.75 A RESOLUTION | 20S PROTEASOME, CELL CYCLE, IMMUNE RESPONSE, PROTEOLYSIS, UBIQUITIN, HYDROLASE
1iru:T (HIS20) to (GLN53) CRYSTAL STRUCTURE OF THE MAMMALIAN 20S PROTEASOME AT 2.75 A RESOLUTION | 20S PROTEASOME, CELL CYCLE, IMMUNE RESPONSE, PROTEOLYSIS, UBIQUITIN, HYDROLASE
1it7:A (ALA254) to (ARG270) CRYSTAL STRUCTURE OF ARCHAEOSINE TRNA-GUANINE TRANSGLYCOSYLASE COMPLEXED WITH GUANINE | (ALPHA/BETA)8 BARREL, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
1it7:B (ALA254) to (ARG270) CRYSTAL STRUCTURE OF ARCHAEOSINE TRNA-GUANINE TRANSGLYCOSYLASE COMPLEXED WITH GUANINE | (ALPHA/BETA)8 BARREL, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
1it8:A (ALA251) to (ARG270) CRYSTAL STRUCTURE OF ARCHAEOSINE TRNA-GUANINE TRANSGLYCOSYLASE FROM PYROCOCCUS HORIKOSHII COMPLEXED WITH ARCHAEOSINE PRECURSOR, PREQ0 | (ALPHA/BETA)8 BARREL, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
4m9l:A (SER275) to (PRO300) DNA POLYMERASE BETA E295K SOAKED WITH DCTP | DNA POLYMERASE, LYASE, DNA COMPLEX, TRANSFERASE-DNA COMPLEX
3wdu:C (GLY176) to (PRO202) THE COMPLEX STRUCTURE OF PTLIC16A WITH CELLOBIOSE | 1,3-1,4-BETA-GLUCANASE, 1,3(4)-BETA-GLUCANASE, PTLIC16A, BETA- JELLYROLL FOLD, HYDROLASE
3wdw:A (GLY176) to (PRO202) THE APO-FORM STRUCTURE OF E113A FROM PAECILOMYCES THERMOPHILA | 1,3-1,4-BETA-GLUCANASE, 1,3(4)-BETA-GLUCANASE, PTLIC16A, BETA- JELLYROLL FOLD, HYDROLASE
5aeg:A (ALA287) to (VAL302) A BACTERIAL PROTEIN STUCTURE IN GLYCOSIDE HYDROLASE FAMILY 31. | HYDROLASE, GH31, ALPHA-SULFOQUINOVOSIDASE
2x2n:A (GLY424) to (ARG475) X-RAY STRUCTURE OF CYP51 FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH POSACONAZOLE IN TWO DIFFERENT CONFORMATIONS | OXIDOREDUCTASE, P450, METAL-BINDING, METHYLTRANSFERASE, ERGOSTEROL BIOSYNTHESIS
2x53:1 (SER171) to (PHE208) STRUCTURE OF THE PHAGE P2 BASEPLATE IN ITS ACTIVATED CONFORMATION WITH SR | BASEPLATE, VIRAL PROTEIN
2x53:Y (SER171) to (PHE208) STRUCTURE OF THE PHAGE P2 BASEPLATE IN ITS ACTIVATED CONFORMATION WITH SR | BASEPLATE, VIRAL PROTEIN
2x53:Z (SER171) to (PHE208) STRUCTURE OF THE PHAGE P2 BASEPLATE IN ITS ACTIVATED CONFORMATION WITH SR | BASEPLATE, VIRAL PROTEIN
2isb:A (GLY131) to (ARG162) CRYSTAL STRUCTURE OF FUMARASE OF FUM-1 (NP_069927.1) FROM ARCHAEOGLOBUS FULGIDUS AT 1.66 A RESOLUTION | NP_069927.1, FUMARASE OF FUM-1, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, LYASE
2isj:A (GLU171) to (PHE194) BLUB BOUND TO OXIDIZED FMN | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, FLAVOPROTEIN
2isj:B (GLU171) to (PHE194) BLUB BOUND TO OXIDIZED FMN | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, FLAVOPROTEIN
2isj:C (GLU171) to (PHE194) BLUB BOUND TO OXIDIZED FMN | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, FLAVOPROTEIN
2isj:D (SER172) to (PHE194) BLUB BOUND TO OXIDIZED FMN | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, FLAVOPROTEIN
2isj:E (GLU171) to (PHE194) BLUB BOUND TO OXIDIZED FMN | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, FLAVOPROTEIN
2isj:G (GLU171) to (PHE194) BLUB BOUND TO OXIDIZED FMN | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, FLAVOPROTEIN
2isj:H (GLU171) to (PHE194) BLUB BOUND TO OXIDIZED FMN | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, FLAVOPROTEIN
2isl:A (GLU171) to (PHE194) BLUB BOUND TO REDUCED FLAVIN (FMNH2) AND MOLECULAR OXYGEN. (CLEAR CRYSTAL FORM) | FLAVIN, OXIDOREDUCTASE, MONOOXYGENASE, FLAVIN DESTRUCTASE, MOLECULAR OXYGEN,, FLAVOPROTEIN
2isl:C (GLU171) to (PHE194) BLUB BOUND TO REDUCED FLAVIN (FMNH2) AND MOLECULAR OXYGEN. (CLEAR CRYSTAL FORM) | FLAVIN, OXIDOREDUCTASE, MONOOXYGENASE, FLAVIN DESTRUCTASE, MOLECULAR OXYGEN,, FLAVOPROTEIN
2x7y:B (GLY402) to (LYS452) P450 BM3 F87A IN COMPLEX WITH DMSO | ELECTRON TRANSPORT, OXIDOREDUCTASE, DMSO-INHIBITION, METAL-BINDING
1jpz:B (GLY402) to (LYS452) CRYSTAL STRUCTURE OF A COMPLEX OF THE HEME DOMAIN OF P450BM- 3 WITH N-PALMITOYLGLYCINE | PROTEIN-SUBSTRATE COMPLEX, HEMEPROTEIN, OXIDOREDUCTASE
1js2:A (ASP15) to (ALA82) CRYSTAL STRUCTURE OF C77S HIPIP: A SERINE LIGATED [4FE-4S] CLUSTER | SERINE LIGATED [4FE-4S] CLUSTER, ELECTRON TRANSPORT
1js2:B (ASP115) to (ALA182) CRYSTAL STRUCTURE OF C77S HIPIP: A SERINE LIGATED [4FE-4S] CLUSTER | SERINE LIGATED [4FE-4S] CLUSTER, ELECTRON TRANSPORT
1js2:C (ASP215) to (ALA282) CRYSTAL STRUCTURE OF C77S HIPIP: A SERINE LIGATED [4FE-4S] CLUSTER | SERINE LIGATED [4FE-4S] CLUSTER, ELECTRON TRANSPORT
1js2:D (ASP315) to (ALA382) CRYSTAL STRUCTURE OF C77S HIPIP: A SERINE LIGATED [4FE-4S] CLUSTER | SERINE LIGATED [4FE-4S] CLUSTER, ELECTRON TRANSPORT
3wwm:A (SER38) to (ARG64) CRYSTAL STRUCTURE OF LYSZ FROM THERMUS THERMOPHILUS WITH ADP | AMINO ACID KINASE, TRANSFERASE
3wz8:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH GEWALD REACTION-DERIVED INHIBITOR (8) | ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2jc4:A (SER222) to (TRP256) 3'-5' EXONUCLEASE (NEXO) FROM NEISSERIA MENINGITIDIS | HYDROLASE, NEISSERIA MENINGITIDIS, REPAIR PHOSPHODIESTERASE, DNA REPAIR, EXONUCLEASE, ENDONUCLEASE
2jc5:A (SER45) to (LYS74) APURINIC APYRIMIDINIC (AP) ENDONUCLEASE (NAPE) FROM NEISSERIA MENINGITIDIS | HYDROLASE, NEISSERIA MENINGITIDIS, REPAIR PHOSPHODIESTERASE, DNA REPAIR, EXONUCLEASE, ENDONUCLEASE
4n7d:A (SER36) to (TYR59) SELENOMETHIONINE INCORPORATED BLA G 4 | ALLERGEN, BETA BARREL, COCKROACH, GLYCOPROTEIN, SECRETED
1k3d:A (SER98) to (THR139) PHOSPHOENOLPYRUVATE CARBOXYKINASE IN COMPLEX WITH ADP AND ALF3 | KINASE, GLUCONEOGENESIS, NUCLEOTIDE-TRIPHOSPHATE HYDROLASE., LYASE
4ncx:B (GLY602) to (ASN623) CRYSTAL STRUCTURE OF PROLYL-TRNA SYNTHETASE (PRORS, PROLINE--TRNA LIGASE) FROM PLASMODIUM FALCIPARUM 3D7 | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, LIGASE, PROLYL-TRNA SYNTHETASE
2jli:A (GLN240) to (LYS274) ATOMIC RESOLUTION STRUCTURE OF THE CYTOPLASMIC DOMAIN OF YERSINIA PESTIS YSCU, A REGULATORY SWITCH INVOLVED IN TYPE III SECRETION | CELL MEMBRANE, TRANSMEMBRANE, YERSINIA PESTIS, PROTEIN TRANSPORT, TYPE III SECRETION SYSTEM, PLASMID, MEMBRANE, VIRULENCE, TRANSPORT
2jx8:A (PRO2) to (ASN25) SOLUTION STRUCTURE OF HPCIF1 WW DOMAIN | PROTEIN FRAGMENT, WW DOMAIN, TRIPLE-STANDED BETA-SHEET, ALPHA-HELIX, NUCLEUS, PHOSPHORYLATION, TRANSCRIPTION
1wep:A (GLU45) to (GLY75) SOLUTION STRUCTURE OF PHD DOMAIN IN PHF8 | NMR, STRUCTURAL GENOMICS, PHD DOMAIN, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, DNA BINDING PROTEIN
3zjg:B (LYS299) to (ASN326) A20 OTU DOMAIN WITH IRREVERSIBLY OXIDISED CYS103 FROM 60 MIN H2O2 SOAK. | HYDROLASE, UBIQUITIN, DEUBIQUITINATING ENZYME, REVERSIBLE OXIDATION, SULPHENIC ACID, SULPHINIC ACID, SULPHONIC ACID, CYS PROTEASE
3zks:A (GLY346) to (ALA368) BACE2 XAPERONE COMPLEX WITH INHIBITOR | HYDROLASE-IMMUNE SYSTEM COMPLEX, INHIBITOR, NANOBODY
2krt:A (ASP74) to (GLY107) SOLUTION NMR STRUCTURE OF A CONSERVED HYPOTHETICAL MEMBRANE LIPOPROTEIN OBTAINED FROM UREAPLASMA PARVUM: NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET UUR17A (139-239) | LIPOPROTEIN, NESG, UUR17A, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM
1wu7:B (GLY390) to (ASN411) CRYSTAL STRUCTURE OF HISTIDYL-TRNA SYNTHETASE FROM THERMOPLASMA ACIDOPHILUM | LIGASE, STRUCTURAL GENOMICS, DIMER
2ma7:A (VAL30) to (THR54) SOLUTION NMR STRUCTURE OF ZINC FINGER PROTEIN EOS FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR7992A | STRUCTURAL GENOMICS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, DNA BINDING PROTEIN
5c4v:C (SER411) to (LYS436) SKI-LIKE PROTEIN | COMPLEX, SIGNALING PROTEIN
2mjd:A (GLU66) to (THR106) OXIDIZED YEAST ADRENODOXIN HOMOLOG 1 | FERREDOXIN, IRON SULFUR ASSEMBLY, PARAMAGNETIC PROTEIN, 2FE2S CLUSTER, METAL BINDING PROTEIN
5c9b:D (MSE211) to (TYR231) CRYSTAL STRUCTURE OF A RETROPEPSIN-LIKE ASPARTIC PROTEASE FROM RICKETTSIA CONORII | PEPSIN, APRICK, HYDROLASE
5c9f:B (MET211) to (ALA234) CRYSTAL STRUCTURE OF A RETROPEPSIN-LIKE ASPARTIC PROTEASE FROM RICKETTSIA CONORII | PEPSIN, APRICK, HYDROLASE
5c9f:C (MET211) to (ALA234) CRYSTAL STRUCTURE OF A RETROPEPSIN-LIKE ASPARTIC PROTEASE FROM RICKETTSIA CONORII | PEPSIN, APRICK, HYDROLASE
3jsa:A (ASP275) to (ASP304) HOMOSERINE DEHYDROGENASE FROM THERMOPLASMA VOLCANIUM COMPLEXED WITH NAD | STRUCTURAL GENOMICS, APC89447, HOMOSERINE, DEHYDROGENASE, NAD, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, OXIDOREDUCTASE
3k1o:A (GLN425) to (ARG475) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA CRUZI IN COMPLEX WITH A POTENTIAL ANTICHAGASIC DRUG, POSACONAZOLE | STEROL 14-ALPHA DEMETHYLASE, EBURICOL 14A-DEMETHYLASE, CYP51, CYTOCHROME P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, ENDOPLASMIC RETICULUM, TRANSMEMBRANE PROTEIN, STEROL BIOSYNTHESIS, LIPIDS, MEMBRANE, IRON, HEME-THIOLATE PROTEIN
5csa:B (GLY1303) to (SER1327) CRYSTAL STRUCTURE OF DOMAINS BT-BCCP-AC1-AC5 OF YEAST ACETYL-COA CARBOXYLASE | ACETYL-COA CARBOXYLASE, LIGASE
3kew:A (ASN200) to (GLY226) CRYSTAL STRUCTURE OF PROBABLE ALANYL-TRNA-SYNTHASE FROM CLOSTRIDIUM PERFRINGENS | STRUCTURAL GENOMICS, PSI-2, TRNA SYNTHASE, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, TRANSFERASE
1m78:A (LYS161) to (TYR186) CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 5-CHLORYL-2,4,6-QUINAZOLINETRIAMINE (GW1225) | OXIDOREDUCTASE, ANTIFUNGAL TARGET, REDUCTASE
1m79:A (LYS161) to (TYR186) CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 5-(4-METHOXYPHENOXY)-2,4-QUINAZOLINEDIAMINE (GW1466) | OXIDOREDUCTASE, ANTIFUNGAL TARGET, REDUCTASE
1xx5:C (TRP121) to (CYS148) CRYSTAL STRUCTURE OF NATRIN FROM NAJA ATRA SNAKE VENOM | NATRIN, CRISPS, NAJA ATRA, TOXIN
3kl0:A (ASP189) to (MET227) CRYSTAL STRUCTURE OF THE GLUCURONOXYLAN XYLANOHYDROLASE XYNC FROM BACILLUS SUBTILIS | ALPHA BETA BARREL, (BETA/ALPHA)8 BARREL (BETA/ALPHA)8 + BETA DUAL MOTIF FAMILY, HYDROLASE
4p0y:B (LYS34) to (ASP54) STRUCTURE OF THE DOUBLE STRANDED DNA BINDING TYPE IV SECRETION PROTEIN TRAN FROM ENTEROCOCCUS | GRAM-POSITIVE, CONJUGATION, HELIX-TURN-HELIX, DSDNA BINDING, DNA BINDING PROTEIN
4p0z:A (LYS34) to (ASP54) STRUCTURE OF THE DOUBLE STRANDED DNA BINDING TYPE IV SECRETION PROTEIN TRAN FROM ENTEROCOCCUS | GRAM-POSITIVE, CONJUGATION, HELIX-TURN-HELIX, DSDNA BINDING, DNA BINDING PROTEIN
3a39:A (ASP11) to (ALA76) CRYSTAL STRUCTURE OF HIGH-POTENTIAL IRON-SULFUR PROTEIN FROM THERMOCHROMATIUM TEPIDUM AT 0.72 ANGSTROM RESOLUTION | IRON-SULFUR CLUSTER, ELECTRON TRANSPORT
5d8v:A (ASP11) to (ALA76) ULTRA-HIGH RESOLUTION STRUCTURE OF HIGH-POTENTIAL IRON-SULFUR PROTEIN | IRON-SULFUR PROTEIN, METAL BINDING PROTEIN
1ygs:A (SER411) to (LYS436) CRYSTAL STRUCTURE OF THE SMAD4 TUMOR SUPPRESSOR C-TERMINAL DOMAIN | SMAD4, TUMOR SUPPRESSOR C-TERMINAL DOMAIN, TGF-BETA SIGNAL MEDIATOR, BETA-SANDWICH SCAFFOLD WITH A THREE-HELIX BUNDLE, TUMOUR SUPPRESSOR
1n0f:C (PRO44) to (LYS69) CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF | CELL DIVISION, CELL WALL BIOSYNTHESIS PROTEIN, STRUCTURAL GENOMICS, BSGC STRUCTURE FUNDED BY NIH, PROTEIN STRUCTURE INITIATIVE, PSI, BERKELEY STRUCTURAL GENOMICS CENTER, BIOSYNTHETIC PROTEIN
1n0f:D (PRO44) to (LYS69) CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF | CELL DIVISION, CELL WALL BIOSYNTHESIS PROTEIN, STRUCTURAL GENOMICS, BSGC STRUCTURE FUNDED BY NIH, PROTEIN STRUCTURE INITIATIVE, PSI, BERKELEY STRUCTURAL GENOMICS CENTER, BIOSYNTHETIC PROTEIN
1n0f:G (PRO44) to (LYS69) CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF | CELL DIVISION, CELL WALL BIOSYNTHESIS PROTEIN, STRUCTURAL GENOMICS, BSGC STRUCTURE FUNDED BY NIH, PROTEIN STRUCTURE INITIATIVE, PSI, BERKELEY STRUCTURAL GENOMICS CENTER, BIOSYNTHETIC PROTEIN
1n0f:H (PRO44) to (LYS69) CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF | CELL DIVISION, CELL WALL BIOSYNTHESIS PROTEIN, STRUCTURAL GENOMICS, BSGC STRUCTURE FUNDED BY NIH, PROTEIN STRUCTURE INITIATIVE, PSI, BERKELEY STRUCTURAL GENOMICS CENTER, BIOSYNTHETIC PROTEIN
3kx3:B (GLY402) to (LYS452) CRYSTAL STRUCTURE OF BACILLUS MEGATERIUM BM3 HEME DOMAIN MUTANT L86E | CYTOCHROME P450, L86E MUTANT, HEME DOMAIN, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3kx4:A (GLY402) to (LYS452) CRYSTAL STRUCTURE OF BACILLUS MEGATERIUM BM3 HEME DOMAIN MUTANT I401E | CYTOCHROME P450, I401E MUTANT, HEME DOMAIN, CYTOPLASM, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, HEME, IRON, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
3l38:A (GLY396) to (VAL418) BACE1 IN COMPLEX WITH THE AMINOPYRIDINE COMPOUND 44 | BETA-SECRETASE, BACE-1, AMINOPYRIDINE, INHIBITOR, ASPARTYL PROTEASE, DISULFIDE BOND, PROTEASE, TRANSMEMBRANE, ZYMOGEN, HYDROLASE
3l4d:C (GLY424) to (LYS476) CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM LEISHMANIA INFANTUM IN COMPLEX WITH FLUCONAZOLE | STEROL 14-ALPHA DEMETHYLASE, CYP51, P450, HEME, OXIDOREDUCTASE, MONOOXYGENASE, ENDOPLASMIC RETICULUM, TRANSMEMBRANE PROTEIN, STEROL BIOSYNTHESIS, OBTUSIFOLIOL, LIPIDS, MEMBRANE, IRON
3agl:B (ALA147) to (ARG190) COMPLEX OF PKA WITH THE BISUBSTRATE PROTEIN KINASE INHIBITOR ARC-1039 | PKA, PROTEIN KINASE A, BISUBSTRATE INHIBITOR, ARC-1039, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
5dni:A (CYS129) to (ASN162) CRYSTAL STRUCTURE OF METHANOCALDOCOCCUS JANNASCHII FUMARATE HYDRATASE BETA SUBUNIT | ALPHA BETA BARREL, LYASE
5dni:B (CYS129) to (ASN162) CRYSTAL STRUCTURE OF METHANOCALDOCOCCUS JANNASCHII FUMARATE HYDRATASE BETA SUBUNIT | ALPHA BETA BARREL, LYASE
3lcb:B (CYS289) to (LEU328) THE CRYSTAL STRUCTURE OF ISOCITRATE DEHYDROGENASE KINASE/PHOSPHATASE IN COMPLEX WITH ITS SUBSTRATE, ISOCITRATE DEHYDROGENASE, FROM ESCHERICHIA COLI. | KINASE PHOSPHATASE, GLYOXYLATE BYPASS, HYDROLASEPROTEIN PHOSPHATASE, TRICARBOXYLIC ACID CYCLE, ISOCITRATE, TRANSFERASE, HYDROLASE
3ld6:A (GLU452) to (ARG500) CRYSTAL STRUCTURE OF HUMAN LANOSTEROL 14ALPHA-DEMETHYLASE (CYP51) IN COMPLEX WITH KETOCONAZOLE | CYTOCHROME P450, STEROL 14ALPHA-DEMETHYLASE, KETOCONAZOLE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, ALTERNATIVE SPLICING, CHOLESTEROL BIOSYNTHESIS, ENDOPLASMIC RETICULUM, HEME, IRON, LIPID SYNTHESIS, MEMBRANE, METAL-BINDING, MICROSOME, MONOOXYGENASE, NADP, OXIDOREDUCTASE, POLYMORPHISM, STEROID BIOSYNTHESIS, STEROL BIOSYNTHESIS, TRANSMEMBRANE
5dq4:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH FRAGMENT 66 | FRAGMENT SCREENING, HYDROLASE, INHIBITION
5dr4:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH FRAGMENT 231 | FRAGMENT SCREENING, HYDROLASE, INHIBITION
4ape:A (GLY303) to (SER325) THE ACTIVE SITE OF ASPARTIC PROTEINASES | HYDROLASE (ACID PROTEINASE)
1zfi:A (ALA40) to (PRO64) SOLUTION STRUCTURE OF THE LEECH CARBOXYPEPTIDASE INHIBITOR | CARBOXYPEPTIDASE INHIBITOR, FIVE-STRANDED ANTIPARALLEL BETA- SHEET, ONE SHORT ALPHA-HELIX, HYDROLASE INHIBITOR
4pzw:A (GLY395) to (VAL417) SYNTHESIS, CHARACTERIZATION AND PK/PD STUDIES OF A SERIES OF SPIROCYCLIC PYRANOCHROMENE BACE1 INHIBITORS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ar9:A (ILE341) to (ALA368) CRYSTAL STRUCTURE OF THE PEPTIDASE DOMAIN OF COLLAGENASE T FROM CLOSTRIDIUM TETANI AT 1.69 ANGSTROM RESOLUTION. | HYDROLASE, COLLAGEN, METALLOPROTEASE, PEPTIDASE, COLLAGENOLYSIS
4ar9:B (ILE341) to (ALA368) CRYSTAL STRUCTURE OF THE PEPTIDASE DOMAIN OF COLLAGENASE T FROM CLOSTRIDIUM TETANI AT 1.69 ANGSTROM RESOLUTION. | HYDROLASE, COLLAGEN, METALLOPROTEASE, PEPTIDASE, COLLAGENOLYSIS
3lmm:A (GLN372) to (ARG409) CRYSTAL STRUCTURE OF THE DIP2311 PROTEIN FROM CORYNEBACTERIUM DIPHTHERIAE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET CDR35 | MULTI-DOMAINED ALPHA-BETA PROTEIN, STRUCTURAL GENOMICS, PSI- 2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
3lmm:C (LYS371) to (ARG409) CRYSTAL STRUCTURE OF THE DIP2311 PROTEIN FROM CORYNEBACTERIUM DIPHTHERIAE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET CDR35 | MULTI-DOMAINED ALPHA-BETA PROTEIN, STRUCTURAL GENOMICS, PSI- 2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
1zoa:A (GLY402) to (LYS452) CRYSTAL STRUCTURE OF A328V MUTANT OF THE HEME DOMAIN OF P450BM-3 WITH N-PALMITOYLGLYCINE | CYTOCHROME P-450, HEMEPROTEIN A328V, OXIDOREDUCTASE
3apv:A (GLU35) to (THR67) CRYSTAL STRUCTURE OF THE A VARIANT OF HUMAN ALPHA1-ACID GLYCOPROTEIN AND AMITRIPTYLINE COMPLEX | BETA BARREL, PLASMA PROTEIN, TRANSPORT PROTEIN
3apv:B (GLU35) to (THR67) CRYSTAL STRUCTURE OF THE A VARIANT OF HUMAN ALPHA1-ACID GLYCOPROTEIN AND AMITRIPTYLINE COMPLEX | BETA BARREL, PLASMA PROTEIN, TRANSPORT PROTEIN
3apx:A (ASN34) to (THR67) CRYSTAL STRUCTURE OF THE A VARIANT OF HUMAN ALPHA1-ACID GLYCOPROTEIN AND CHLORPROMAZINE COMPLEX | BETA BARREL, PLASMA PROTEIN, TRANSPORT PROTEIN
5e78:A (GLY402) to (LYS452) CRYSTAL STRUCTURE OF P450 BM3 HEME DOMAIN VARIANT COMPLEXED WITH CO(III)SEP | BM3, P450, MEDIATED ELECTRON TRANSPORT, CO(III)SEP, OXIDOREDUCTASE
3m0h:C (PRO55) to (THR72) CRYSTAL STRUCTURE OF PSEUDOMONAS STUTZERI L-RHAMNOSE ISOMERASE MUTANT S329F IN COMPLEX WITH L-RHAMNOSE | BETA/ALPHA BARREL, HOMO-TETRAMER, METAL-BINDING PROTEIN, TIM BARREL, ISOMERASE
3m0x:A (PRO55) to (THR72) CRYSTAL STRUCTURE OF PSEUDOMONAS STUTZERI L-RHAMNOSE ISOMERASE MUTANT S329L IN COMPLEX WITH D-PSICOSE | BETA/ALPHA BARREL, HOMO-TETRAMER, METAL-BINDING PROTEIN, TIM BARREL, ISOMERASE
3m0x:D (PRO55) to (THR72) CRYSTAL STRUCTURE OF PSEUDOMONAS STUTZERI L-RHAMNOSE ISOMERASE MUTANT S329L IN COMPLEX WITH D-PSICOSE | BETA/ALPHA BARREL, HOMO-TETRAMER, METAL-BINDING PROTEIN, TIM BARREL, ISOMERASE
4qaw:A (ASP188) to (MET226) STRUCTURE OF MODULAR XYN30D FROM PAENIBACILLUS BARCINONENSIS | TIM BARREL, BETA-STRUCTURE, HYDROLASE, CARBOHYDRATE/SUGAR BINDING, CALCIUM BINDING, TIM BARREL BETA-STRUCTURE, CARBOHYDRATE/SUGAR BINDING CALCIUM BINDING, PLANT-CELL WALL DEGRADATION
4qaw:C (ASP188) to (MET226) STRUCTURE OF MODULAR XYN30D FROM PAENIBACILLUS BARCINONENSIS | TIM BARREL, BETA-STRUCTURE, HYDROLASE, CARBOHYDRATE/SUGAR BINDING, CALCIUM BINDING, TIM BARREL BETA-STRUCTURE, CARBOHYDRATE/SUGAR BINDING CALCIUM BINDING, PLANT-CELL WALL DEGRADATION
4qaw:D (ASP188) to (MET226) STRUCTURE OF MODULAR XYN30D FROM PAENIBACILLUS BARCINONENSIS | TIM BARREL, BETA-STRUCTURE, HYDROLASE, CARBOHYDRATE/SUGAR BINDING, CALCIUM BINDING, TIM BARREL BETA-STRUCTURE, CARBOHYDRATE/SUGAR BINDING CALCIUM BINDING, PLANT-CELL WALL DEGRADATION
4qaw:H (ASP188) to (MET226) STRUCTURE OF MODULAR XYN30D FROM PAENIBACILLUS BARCINONENSIS | TIM BARREL, BETA-STRUCTURE, HYDROLASE, CARBOHYDRATE/SUGAR BINDING, CALCIUM BINDING, TIM BARREL BETA-STRUCTURE, CARBOHYDRATE/SUGAR BINDING CALCIUM BINDING, PLANT-CELL WALL DEGRADATION
5ean:A (ALA20) to (THR55) CRYSTAL STRUCTURE OF DNA2 IN COMPLEX WITH A 5' OVERHANG DNA | DNA BINDING PROTEIN, HYDROLASE-DNA COMPLEX
4b5f:A (SER45) to (LYS74) SUBSTRATE BOUND NEISSERIA AP ENDONUCLEASE IN ABSENCE OF METAL IONS (CRYSTAL FORM 1) | HYDROLASE-DNA COMPLEX
4b5g:A (SER45) to (LYS74) SUBSTRATE BOUND NEISSERIA AP ENDONUCLEASE IN ABSENCE OF METAL IONS (CRYSTAL FORM 2) | HYDROLASE-DNA COMPLEX
4b5g:B (SER45) to (LYS74) SUBSTRATE BOUND NEISSERIA AP ENDONUCLEASE IN ABSENCE OF METAL IONS (CRYSTAL FORM 2) | HYDROLASE-DNA COMPLEX
4b5g:C (SER45) to (LYS74) SUBSTRATE BOUND NEISSERIA AP ENDONUCLEASE IN ABSENCE OF METAL IONS (CRYSTAL FORM 2) | HYDROLASE-DNA COMPLEX
4b5h:A (SER45) to (LYS74) SUBSTATE BOUND INACTIVE MUTANT OF NEISSERIA AP ENDONUCLEASE IN PRESENCE OF METAL IONS | HYDROLASE-DNA COMPLEX
4b5i:A (SER45) to (LYS74) PRODUCT COMPLEX OF NEISSERIA AP ENDONUCLEASE IN PRESENCE OF METAL IONS | HYDROLASE-DNA COMPLEX
4b5j:A (SER45) to (LYS74) NEISSERIA AP ENDONUCLEASE BOUND TO THE SUBSTRATE WITH AN ORPHAN ADENINE BASE | HYDROLASE-DNA COMPLEX
4b5m:A (SER45) to (LYS74) NEISSERIA AP ENDONUCLEASE BOUND TO THE SUBSTRATE WITH A CYTOSINE ORPHAN BASE | HYDROLASE-DNA COMPLEX
4b5m:B (SER45) to (LYS74) NEISSERIA AP ENDONUCLEASE BOUND TO THE SUBSTRATE WITH A CYTOSINE ORPHAN BASE | HYDROLASE-DNA COMPLEX
4b5m:C (SER45) to (LYS74) NEISSERIA AP ENDONUCLEASE BOUND TO THE SUBSTRATE WITH A CYTOSINE ORPHAN BASE | HYDROLASE-DNA COMPLEX
5ee9:B (ILE291) to (ARG321) COMPLEX STRUCTURE OF OSYCHF1 WITH GMP-PNP | OSYCHF1, GTP-BINDING PROTEIN, ATP, AMP-PNP, YCHF-TYPE, P-LOOP NTPASE, HYDROLASE
4bjk:C (GLN425) to (ARG475) CYP51 OF TRYPANOSOMA BRUCEI BOUND TO (S)-N-(3-(1H-INDOL-3- YL)-1-OXO-1-(PYRIDIN-4-YLAMINO)PROPAN-2-YL)-3,3'-DIFLUORO-( 1,1'-BIPHENYL)-4-CARBOXAMIDE | OXIDOREDUCTASE, ERGOSTEROL BIOSYNTHESIS
4bmm:A (GLN425) to (LYS477) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- YLAMINO)PROPAN-2-YL)- 2',3,5'-TRIFLUORO-(1,1'-BIPHENYL)-4-CARBOXAMIDE | OXIDOREDUCTASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
4r1z:B (GLU456) to (VAL506) ZEBRA FISH CYTOCHROME P450 17A1 WITH ABIRATERONE | CYTOCHROME P450 17A1, ABIRATERONE, 17 (ALPHA)-HYDROXYLATION, 17ALPHA, 20-LYASE, STEROID BIOSYNTHESIS, ENZYME KINETICS, OXIDOREDUCTASE
4r3o:F (HIS20) to (GLN53) HUMAN CONSTITUTIVE 20S PROTEASOME | HYDROLASE
4r3o:T (HIS20) to (GLN53) HUMAN CONSTITUTIVE 20S PROTEASOME | HYDROLASE
3c8m:A (ASP275) to (ASP304) CRYSTAL STRUCTURE OF HOMOSERINE DEHYDROGENASE FROM THERMOPLASMA VOLCANIUM | STRUCTURAL GENOMICS, APC89447, HOMOSERINE, DEHYDROGENASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, OXIDOREDUCTASE
3c9x:A (GLY303) to (GLN325) CRYSTAL STRUCTURE OF TRICHODERMA REESEI ASPARTIC PROTEINASE | ASPARTIC PROTEINASE, ASPARTYL PROTEASE, HYDROLASE, PROTEASE
3na1:A (ARG426) to (PRO474) CRYSTAL STRUCTURE OF HUMAN CYP11A1 IN COMPLEX WITH 20- HYDROXYCHOLESTEROL | CYTOCHROME P450, 20-HYDROXYCHOLESTEROL, CHOLESTEROL SIDE CHAIN CLEAVAGE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE, ELECTRON TRANSPORT
4c0c:A (GLY424) to (ARG475) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- YLAMINO)PROPAN-2-YL)-4-(4-(2,4-DIFLUOROPHENYL)PIPERAZIN-1- YL)-2-FLUOROBENZAMIDE. | OXIDOREDUCTASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
3cbd:A (GLY402) to (LYS452) DIRECTED EVOLUTION OF CYTOCHROME P450 BM3, TO OCTANE MONOXYGENASE 139-3 | CYTOCHROME P450, HEMEPROTEIN 139-3, ELECTRON TRANSPORT, FAD, FLAVOPROTEIN, FMN, IRON, MEMBRANE, METAL-BINDING, MONOOXYGENASE, MULTIFUNCTIONAL ENZYME, NADP, OXIDOREDUCTASE, TRANSPORT
4c27:A (GLN425) to (ARG475) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- 4-YLAMINO)PROPAN-2-YL)-2-FLUORO-4-(4-(4-(TRIFLUOROMETHYL) PHENYL)PIPERAZIN-1-YL)BENZAMIDE | OXIDOREDUCTASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
4c27:B (GLN425) to (ARG475) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- 4-YLAMINO)PROPAN-2-YL)-2-FLUORO-4-(4-(4-(TRIFLUOROMETHYL) PHENYL)PIPERAZIN-1-YL)BENZAMIDE | OXIDOREDUCTASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
4ccd:A (ASP224) to (SER256) STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH D-GALACTAL: ENZYME-INTERMEDIATE COMPLEX | HYDROLASE, KRABBE DISEASE, GLYCOSYL HYDROLASE, GALACTOSIDASE, D-GALACTAL, LYSOSOMAL STORAGE DISEASE, ENZYME-INTERMEDIATE COMPLEX
4rrn:A (GLY395) to (VAL417) 8-TETRAHYDROPYRAN-2-YL CHROMANS: HIGHLY SELECTIVE BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1 (BACE1) INHIBITORS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3cvo:C (ARG157) to (PRO183) CRYSTAL STRUCTURE OF A METHYLTRANSFERASE-LIKE PROTEIN (SPO2022) FROM SILICIBACTER POMEROYI DSS-3 AT 1.80 A RESOLUTION | ROSSMANN FOLD, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, TRANSFERASE
3cvo:D (ARG157) to (PRO183) CRYSTAL STRUCTURE OF A METHYLTRANSFERASE-LIKE PROTEIN (SPO2022) FROM SILICIBACTER POMEROYI DSS-3 AT 1.80 A RESOLUTION | ROSSMANN FOLD, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, TRANSFERASE
4coh:A (GLN425) to (ARG475) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE SULFONAMIDE DERIVATIVE OF THE 4-AMINOPYRIDYL-BASED INHIBITOR | TRANSFERASE, CYP51, STEROL 14-DEMETHYLASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
4coh:B (GLN425) to (LYS477) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE SULFONAMIDE DERIVATIVE OF THE 4-AMINOPYRIDYL-BASED INHIBITOR | TRANSFERASE, CYP51, STEROL 14-DEMETHYLASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
3d1j:A (PHE44) to (ASN75) CRYSTAL STRUCTURE OF E.COLI GS MUTANT DMGS(C7S;C408S) | GLYCOSYL-TRANSFERASE, GT-B FOLD, ROSSMANN FOLD, OPEN FORM, GLYCOGEN BIOSYNTHESIS, GLYCOSYLTRANSFERASE
3d3z:A (SER20) to (ASN57) CRYSTAL STRUCTURE OF ACTIBIND A T2 RNASE | RNASE, T2, HYDROLASE
4tl0:A (GLU113) to (LYS167) CRYSTAL STRUCTURE OF DEATH-ASSOCIATED PROTEIN KINASE 1 WITH A CRUCIAL PHOSPHOMIMICKING MUTATION | KINASE, DEATH-ASSOCIATED, CALMODULIN BINDING, ACTIVATION MUTANT, PHOSPHOMIMICKING MUTANT, TRANSFERASE
3dao:A (TRP170) to (ALA188) CRYSTAL STRUCTURE OF A PUTATIVE PHOSPHATSE (EUBREC_1417) FROM EUBACTERIUM RECTALE AT 1.80 A RESOLUTION | PUTATIVE PHOSPHATSE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, HYDROLASE
3dax:A (ARG447) to (PHE501) CRYSTAL STRUCTURE OF HUMAN CYP7A1 | CYTOCHROME P450, CHOLESTEROL, CHOLESTEROL 7-ALPHA HYDROXYLASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, CHOLESTEROL METABOLISM, ENDOPLASMIC RETICULUM, HEME, IRON, LIPID METABOLISM, MEMBRANE, METAL- BINDING, MICROSOME, MONOOXYGENASE, NADP, OXIDOREDUCTASE, POLYMORPHISM, STEROID METABOLISM
3dbg:A (ASP413) to (HIS462) CRYSTAL STRUCTURE OF CYTOCHROME P450 170A1 (CYP170A1) FROM STREPTOMYCES COELICOLOR | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP170A1, MOLECULAR MECHANISM, HEME, IRON, METAL-BINDING, MONOOXYGENASE
3dbg:B (ASP413) to (HIS462) CRYSTAL STRUCTURE OF CYTOCHROME P450 170A1 (CYP170A1) FROM STREPTOMYCES COELICOLOR | STREPTOMYCES, CYTOCHROME P450 OXIDOREDUCTASE, CYP170A1, MOLECULAR MECHANISM, HEME, IRON, METAL-BINDING, MONOOXYGENASE
4tnw:U (GLY166) to (THR191) C. ELEGANS GLUTAMATE-GATED CHLORIDE CHANNEL (GLUCL) IN COMPLEX WITH FAB AND POPC IN A LIPID-MODULATED CONFORMATION | MEMBRANE PROTEIN, LIGAND-GATED ION CHANNEL, NEUROTRANSMITTER RECEPTOR, CYS-LOOP RECEPTOR, TRANSPORT PROTEIN-IMMUNE SYSTEM COMPLEX
3dcj:B (GLU173) to (MET208) CRYSTAL STRUCTURE OF GLYCINAMIDE FORMYLTRANSFERASE (PURN) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 5-METHYL-5, 6,7,8-TETRAHYDROFOLIC ACID DERIVATIVE | GLYCINAMIDE FORMYLTRANSFERASE, PURN
3dit:A (SER347) to (LYS371) CRYSTAL STRUCTURE OF MAD MH2 DOMAIN | MAD, TGF-BETA, MH2, CYTOPLASM, DEVELOPMENTAL PROTEIN, NUCLEUS, PHOSPHOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, UBL CONJUGATION, SIGNALING PROTEIN
3dit:C (SER347) to (LYS371) CRYSTAL STRUCTURE OF MAD MH2 DOMAIN | MAD, TGF-BETA, MH2, CYTOPLASM, DEVELOPMENTAL PROTEIN, NUCLEUS, PHOSPHOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, UBL CONJUGATION, SIGNALING PROTEIN
4d2p:D (PHE113) to (LYS156) STRUCTURE OF MELK IN COMPLEX WITH INHIBITORS | TRANSFERASE, FRAGMENT STERBASED DRUG DESIGN, KINASE
4d2v:C (PHE113) to (LYS156) STRUCTURE OF MELK IN COMPLEX WITH INHIBITORS | TRANSFERASE, FRAGMENT BASED DRUG DESIGN
3dmu:A (TYR54) to (ASP95) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL NUCLEASE VARIANT PHS T62K AT CRYOGENIC TEMPERATURE | STAPHYLOCOCCAL NUCLEASE, HYPERSTABLE VARIANT, HYDROLASE, PDTP, CALCIUM, ENDONUCLEASE, MEMBRANE, METAL-BINDING, NUCLEASE, SECRETED, ZYMOGEN
4d6z:A (MET445) to (SER495) CYTOCHROME P450 3A4 BOUND TO IMIDAZOLE AND AN INHIBITOR | OXIDOREDUCTASE, MONOOXYGENASE, CYTOCHROME P450, HUMAN CYP3A4, IMIDAZOLE, INHIBITORY COMPLEX
4d75:A (MET445) to (ARG496) CYTOCHROME P450 3A4 BOUND TO AN INHIBITOR | OXIDOREDUCTASE, MONOOXYGENASE, INHIBITORY COMPLEX
4d8i:A (SER254) to (ALA283) HIGH RESOLUTION STRUCTURES OF MONOMERIC S. PYOGENES SPEB REVEALS ROLE OF GLYCINE-RICH ACTIVE SITE LOOP | PAPAIN FOLD, CYSTEINE PROTEASE, SECRETED, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4u1f:A (PRO146) to (MET178) CRYSTAL STRUCTURE OF MIDDLE DOMAIN OF EUKARYOTIC TRANSLATION INITIATION FACTOR EIF3B | TRANSLATION INITIATION, EIF3 COMPLEX, BETA-PROPELLER, TRANSLATION
4u1f:B (PRO146) to (MET178) CRYSTAL STRUCTURE OF MIDDLE DOMAIN OF EUKARYOTIC TRANSLATION INITIATION FACTOR EIF3B | TRANSLATION INITIATION, EIF3 COMPLEX, BETA-PROPELLER, TRANSLATION
3du7:B (ARG48) to (PRO63) TUBULIN-COLCHICINE-PHOMOPSIN A: STATHMIN-LIKE DOMAIN COMPLEX | ALPHA-TUBULIN, BETA-TUBULIN, COLCHICINE, GTPASE, MICROTUBULE, PHOMOPSIN A, STATHMIN, TUBULIN, GTP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, CELL CYCLE
3du7:C (ASP47) to (PRO63) TUBULIN-COLCHICINE-PHOMOPSIN A: STATHMIN-LIKE DOMAIN COMPLEX | ALPHA-TUBULIN, BETA-TUBULIN, COLCHICINE, GTPASE, MICROTUBULE, PHOMOPSIN A, STATHMIN, TUBULIN, GTP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, CELL CYCLE
3du7:D (ARG48) to (PRO63) TUBULIN-COLCHICINE-PHOMOPSIN A: STATHMIN-LIKE DOMAIN COMPLEX | ALPHA-TUBULIN, BETA-TUBULIN, COLCHICINE, GTPASE, MICROTUBULE, PHOMOPSIN A, STATHMIN, TUBULIN, GTP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, CELL CYCLE
3orx:A (ASP178) to (VAL229) PDK1 MUTANT BOUND TO ALLOSTERIC DISULFIDE FRAGMENT INHIBITOR 1F8 | PIF POCKET, C-HELIX, ACTIVATION LOOP, AGC KINASE, TRANSFERASE, ALLOSTERIC INHIBITOR, PHOSPHORYLATION, ALLOSTERY, DISULFIDE, KINASE, PDK1, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3orx:C (ASP178) to (VAL229) PDK1 MUTANT BOUND TO ALLOSTERIC DISULFIDE FRAGMENT INHIBITOR 1F8 | PIF POCKET, C-HELIX, ACTIVATION LOOP, AGC KINASE, TRANSFERASE, ALLOSTERIC INHIBITOR, PHOSPHORYLATION, ALLOSTERY, DISULFIDE, KINASE, PDK1, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3orx:D (ASP178) to (VAL229) PDK1 MUTANT BOUND TO ALLOSTERIC DISULFIDE FRAGMENT INHIBITOR 1F8 | PIF POCKET, C-HELIX, ACTIVATION LOOP, AGC KINASE, TRANSFERASE, ALLOSTERIC INHIBITOR, PHOSPHORYLATION, ALLOSTERY, DISULFIDE, KINASE, PDK1, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3p99:B (GLY424) to (ARG475) STEROL 14ALPHA-DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH DELTA7-14ALPHA-METHYLENE-CYCLOPROPYL-DIHYDROLANOSTEROL | CYTOCHROME P450 FOLD/STEROL 14-ALPHA DEMETHYLASE, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, HEMOPROTEIN, STEROL BIOSYNTHESIS, CYTOCHROME P450 REDUCTASE (CPR), ENDOPLASMIC RETICULUM, MEMBRANE
4dtw:A (GLY402) to (LYS452) CYTOCHROME P450 BM3H-8C8 MRI SENSOR BOUND TO SEROTONIN | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4dub:B (GLY402) to (LYS452) CYTOCHROME P450 BM3H-9D7 MRI SENSOR BOUND TO DOPAMINE | CYTOCHROME P450, MRI CONTRAST SENSOR, DIRECTED EVOLUTION, OXIDOREDUCTASE
4ufm:A (ASP224) to (SER256) MOUSE GALACTOCEREBROSIDASE COMPLEXED WITH 1-DEOXY-GALACTO- NOJIRIMYCIN DGJ | HYDROLASE, COMPLEX, LYSOSOME
4uhl:B (GLY451) to (ARG500) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhl:D (GLY451) to (ARG500) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhl:E (GLY451) to (ARG500) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhl:G (GLU452) to (ARG500) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhl:H (GLY451) to (ARG500) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP | CYTOCHROME P450, CYP51, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
5i3x:A (GLY334) to (VAL356) CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH AMINOQUINOLINE INHIBITOR 6 | ASPARTIC PROTEASE, ALZHEIMER'S DISEASE, APP, AMYLOID PRECURSOR PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5i6f:A (GLY1335) to (GLY1359) CRYSTAL STRUCTURE OF C-TERMINAL VARIANT 1 OF CHAETOMIUM THERMOPHILUM ACETYL-COA CARBOXYLASE | CARBOXYLASE, FATTY ACID METABOLISM, MULTIENZYME, CARRIER PROTEIN- DEPENDENT ENZYME, LIGASE
3pmy:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH A FRAGMENT | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4uqc:A (ASP185) to (MET223) X-RAY STRUCTURE OF GLUCURONOXYLAN-XYLANOHYDROLASE (XYN30A) FROM CLOSTRIDIUM THERMOCELLUM AT 1.30 A RESOLUTION | HYDROLASE
4er1:E (GLY303) to (SER325) THE ACTIVE SITE OF ASPARTIC PROTEINASES | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4er2:E (GLY303) to (SER325) THE ACTIVE SITE OF ASPARTIC PROTEINASES | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3q70:A (GLY307) to (GLN329) SECRETED ASPARTIC PROTEASE IN COMPLEX WITH RITONAVIR | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ez9:A (ILE570) to (GLU620) BACILLUS DNA POLYMERASE I LARGE FRAGMENT COMPLEX 2 | DNA POLYMERASE I, PROTEIN-DNA COMPLEX, CLOSED FORM, TRANSFERASE-DNA COMPLEX
3qdk:B (ARG374) to (LEU407) STRUCTURAL INSIGHT ON MECHANISM AND DIVERSE SUBSTRATE SELECTION STRATEGY OF RIBULOKINASE | STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, PSI-II, ARABINOSE CATABOLISM, ATP BINDING, TRANSFERASE
4fay:B (LEU115) to (ALA136) CRYSTAL STRUCTURE OF A TRIMERIC BACTERIAL MICROCOMPARTMENT SHELL PROTEIN PDUB WITH GLYCEROL METABOLITES | BMC DOMAIN, SHELL PROTEIN, GLYCEROL-BINDING PROTEIN
3r1b:B (GLU439) to (ALA490) OPEN CRYSTAL STRUCTURE OF CYTOCHROME P450 2B4 COVALENTLY BOUND TO THE MECHANISM-BASED INACTIVATOR TERT-BUTYLPHENYLACETYLENE | CYTOCHROME P450 2B4, MONOOXYGENASE, MEMBRANE PROTEIN, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3r5g:A (ILE382) to (ARG412) CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE CYAB FROM P. AERUGINOSA | ADENYLYL CYCLASE, LYASE
5jqu:B (GLY402) to (LYS452) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN G265F/T269V/L272W/L322I/F405M/A406S (WIVS-FM) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqu:C (GLY402) to (LYS452) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN G265F/T269V/L272W/L322I/F405M/A406S (WIVS-FM) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqu:F (GLN403) to (LYS452) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN G265F/T269V/L272W/L322I/F405M/A406S (WIVS-FM) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqv:A (GLY402) to (LYS452) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN T269V/L272W/L322I/A406S (WIVS) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqv:B (GLY402) to (LYS452) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN T269V/L272W/L322I/A406S (WIVS) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
5jqv:F (GLY402) to (LYS452) CRYSTAL STRUCTURE OF CYTOCHROME P450 BM3 HEME DOMAIN T269V/L272W/L322I/A406S (WIVS) VARIANT WITH IRON(III) DEUTEROPORPHYRIN IX BOUND | P450 BM3, IRON(III) DEUTEROPORPHYRIN IX, OXIDOREDUCTASE
4g3j:A (GLY424) to (ARG475) STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH THE VNI DERIVATIVE (R)-N-(1-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4- TRIAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)BENZAMIDE [R- VNI-TRIAZOLE (VNT)] | CYTOCHROME P450 FOLD, HEME, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANE BIOGENESIS, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4g3j:B (GLY424) to (ARG475) STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH THE VNI DERIVATIVE (R)-N-(1-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4- TRIAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)BENZAMIDE [R- VNI-TRIAZOLE (VNT)] | CYTOCHROME P450 FOLD, HEME, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANE BIOGENESIS, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4g3j:D (GLY424) to (ARG475) STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH THE VNI DERIVATIVE (R)-N-(1-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4- TRIAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)BENZAMIDE [R- VNI-TRIAZOLE (VNT)] | CYTOCHROME P450 FOLD, HEME, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANE BIOGENESIS, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4g7g:A (GLY424) to (ARG475) STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH THE VNI DERIVATIVE (R)-N-(1-(3,4'-DIFLUOROBIPHENYL-4-YL)-2-(1H- IMIDAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)BENZAMIDE [VNI/VNF (VFV)] | CYTOCHROME P450 FOLD, HEME, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANE BIOGENESIS, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4g7g:C (GLY424) to (ARG475) STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH THE VNI DERIVATIVE (R)-N-(1-(3,4'-DIFLUOROBIPHENYL-4-YL)-2-(1H- IMIDAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)BENZAMIDE [VNI/VNF (VFV)] | CYTOCHROME P450 FOLD, HEME, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANE BIOGENESIS, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM MEMBRANE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5kg8:A (ASP365) to (PRO388) RIGOR MYOSIN X CO-COMPLEXED WITH AN ACTIN FILAMENT | MYOSIN MOLECULAR MOTORS CYTOSKELETAL MOTILITY, MOTOR PROTEIN
5kix:A (TYR54) to (ALA94) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL NUCLEASE VARIANT DELTA+PHS I92E AT CRYOGENIC TEMPERATURE | NUCLEASE, HYPERSTABLE, PDTP, HYDROLASE, IONIZABLE GROUP
4go5:X (LEU145) to (THR165) THE REGULATORY SUBUNIT OF ASPARTATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS | TRANSFERASE
5lex:S (HIS20) to (GLN53) NATIVE HUMAN 20S PROTEASOME IN MG-ACETATE AT 2.2 ANGSTROM | PROTEASOME, MULTICATALYTIC PROTEINASE, NTN-HYDROLASE, HYDROLASE
5lez:S (HIS20) to (GLN53) HUMAN 20S PROTEASOME COMPLEX WITH OPROZOMIB IN MG-ACETATE AT 2.2 ANGSTROM | PROTEASOME, MULTICATALYTIC PROTEINASE, NTN-HYDROLASE, HYDROLASE
5p0c:A (GLY306) to (SER329) AUTOMATED REFINEMENT OF DIFFRACTION DATA OBTAINED FROM AN ENDOTHIAPEPSIN CRYSTAL TREATED WITH FRAGMENT 59 | FRAGMENT SCREENING, METHOD DEVELOPMENT, ASPARTIC PROTEASE, HYDROLASE
5p3k:A (GLY306) to (SER329) AUTOMATED REFINEMENT OF DIFFRACTION DATA OBTAINED FROM AN ENDOTHIAPEPSIN CRYSTAL TREATED WITH FRAGMENT 173 | FRAGMENT SCREENING, METHOD DEVELOPMENT, ASPARTIC PROTEASE, HYDROLASE
5p3p:A (GLY306) to (SER329) AUTOMATED REFINEMENT OF DIFFRACTION DATA OBTAINED FROM AN ENDOTHIAPEPSIN CRYSTAL TREATED WITH FRAGMENT 178 | FRAGMENT SCREENING, METHOD DEVELOPMENT, ASPARTIC PROTEASE, HYDROLASE
1ady:C (GLY385) to (ARG406) HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH HISTIDYL-ADENYLATE | HISTIDYL-ADENYLATE, AMINO ACID, TRNA SYNTHETASE
1ady:D (GLY385) to (ARG406) HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH HISTIDYL-ADENYLATE | HISTIDYL-ADENYLATE, AMINO ACID, TRNA SYNTHETASE
3emy:A (GLY303) to (GLN325) CRYSTAL STRUCTURE OF TRICHODERMA REESEI ASPARTIC PROTEINASE COMPLEXED WITH PEPSTATIN A | TRICHODERMA REESEI, ASPARTIC PROTEINASE, ASPARTYL PROTEASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4h96:A (LYS161) to (TYR186) CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 5- {3-[3-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-5-METHOXYPHENYL]PROP-1-YN-1- YL}-6-ETHYLPYRIMIDINE-2,4-DIAMINE (UCP1018) | ANTIFUNGAL AGENTS, CANDIDA ALBICANS, DRUG DESIGN, ENZYME INHIBITORS, FUNGAL PROTEINS, TETRAHYDROFOLATE DEHYDROGENASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
4xiv:A (LYS418) to (ASP450) KINASE AND DIMERIZATION (P3P4) OF THE THERMOTOGA MARITIMA CHEA KINASE | P3P4, DIMERIZATION DOMAIN, KINASE DOMAIN, TRANSFERASE
4xiv:B (PRO417) to (ASP450) KINASE AND DIMERIZATION (P3P4) OF THE THERMOTOGA MARITIMA CHEA KINASE | P3P4, DIMERIZATION DOMAIN, KINASE DOMAIN, TRANSFERASE
2d3i:A (PRO493) to (CYS513) CRYSTAL STRUCTURE OF ALUMINUM-BOUND OVOTRANSFERRIN AT 2.15 ANGSTROM RESOLUTION | ALUMINUM, TRANSFERRIN, METAL-BINDING, TRANSPORT, METAL TRANSPORT
4y3g:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH FRAGMENT 285 | FRAGMENT SCREENING, ASPARTIC PROTEASE, INHIBITION, HYDROLASE
3gwb:A (ASP71) to (SER101) CRYSTAL STRUCTURE OF PEPTIDASE M16 INACTIVE DOMAIN FROM PSEUDOMONAS FLUORESCENS. NORTHEAST STRUCTURAL GENOMICS TARGET PLR293L | PEPTIDASE M16 FAMILY, PFL_5859, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, HYDROLASE
3gwb:B (ASP71) to (SER101) CRYSTAL STRUCTURE OF PEPTIDASE M16 INACTIVE DOMAIN FROM PSEUDOMONAS FLUORESCENS. NORTHEAST STRUCTURAL GENOMICS TARGET PLR293L | PEPTIDASE M16 FAMILY, PFL_5859, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, HYDROLASE
2uw7:A (ALA147) to (ARG190) STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH 4-(4-CHLORO- PHENYL)-4-(4-(1H-PYRAZOL-4-YL)-PHENYL)-PIPERIDINE | TRANSFERASE/INHIBITOR, CAMP, KINASE, MYRISTATE, TRANSFERASE, LIPOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, NUCLEOTIDE-BINDING, PROTEIN KINASE INHIBITOR, ATP-BINDING, NUCLEAR PROTEIN, PHOSPHORYLATION, TRANSFERASE/INHIBITOR COMPLEX
2er9:E (GLY303) to (SER325) X-RAY STUDIES OF ASPARTIC PROTEINASE-STATINE INHIBITOR COMPLEXES. | HYDROLASE-HYDROLASE INHIBITOR, ACID PROTEINASE
4k2x:A (SER461) to (ALA482) OXYS ANHYDROTETRACYCLINE HYDROXYLASE FROM STREPTOMYCES RIMOSUS | PARA-HYDROXYBENZOATE HYDROXYLASE FOLD, HYDROXYLASE, FAD BINDING, OXIDOREDUCTASE, FLAVOPROTEIN
3udp:A (GLY334) to (VAL356) CRYSTAL STRUCTURE OF BACE WITH COMPOUND 12 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3udr:A (GLY334) to (VAL356) CRYSTAL STRUCTURE OF BACE WITH COMPOUND 14 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4k9w:C (MET445) to (SER495) COMPLEX OF HUMAN CYP3A4 WITH A DESOXYRITONAVIR ANALOG | CYTOCHROME P450 3A4, ALPHA-BETA PROTEIN, CYTOCHROME P450 FOLD, MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4k9w:D (MET445) to (SER495) COMPLEX OF HUMAN CYP3A4 WITH A DESOXYRITONAVIR ANALOG | CYTOCHROME P450 3A4, ALPHA-BETA PROTEIN, CYTOCHROME P450 FOLD, MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
1g88:C (SER411) to (LYS436) S4AFL3ARG515 MUTANT | TRANSCRIPTIONAL FACTOR, L3 LOOP MUTANT
2fqm:B (ALA149) to (LYS170) CRYSTAL STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF THE PHOSPHOPROTEIN OF VESICULAR STOMATITIS VIRUS | NEGATIVE STRAND RNA VIRUS, POLYMERASE, REPLICATION, COFACTOR, VIRAL PROTEIN
4zf6:A (GLY402) to (LYS452) CYTOCHROME P450 PENTAMUTANT FROM BM3 WITH BOUND PEG | CYTOCHROME P450, HEME OXIDASE DOMAIN, OXIDOREDUCTASE, BACILLUS MEGATERIUM
1smj:C (GLY402) to (LYS452) STRUCTURE OF THE A264E MUTANT OF CYTOCHROME P450 BM3 COMPLEXED WITH PALMITOLEATE | MONOOXYGENASE; FATTY ACID OXYGENASE; CYTOCHROME P450; SUBSTRATE BINDING; PALMITOLEATE, OXIDOREDUCTASE
3ing:A (ASN271) to (SER299) CRYSTAL STRUCTURE OF HOMOSERINE DEHYDROGENASE (NP_394635.1) FROM THERMOPLASMA ACIDOPHILUM AT 1.95 A RESOLUTION | NP_394635.1, HOMOSERINE DEHYDROGENASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, OXIDOREDUCTASE
2h6s:A (GLY307) to (GLN329) SECRETED ASPARTIC PROTEINASE (SAP) 3 FROM CANDIDA ALBICANS | ASPARTIC PROTEINASE, HYDROLASE
1hy0:B (ARG113) to (TRP169) CRYSTAL STRUCTURE OF WILD TYPE DUCK DELTA 1 CRYSTALLIN (EYE LENS PROTEIN) | EYE LENS PROTEIN, DELTA 1 CRYSTALLIN, ARGININOSUCCINATE LYASE, LYASE
3w6s:C (ILE6) to (PHE48) YEAST N-ACETYLTRANSFERASE MPR1 INVOLVED IN OXIDATIVE STRESS TOLERANCE VIA PROLINE METABOLISM | DETOXIFICATION OF L-AZETIDINE-2-CARBOXYLATE, ANTIOXIDANT ENZYME, TRANSFERASE
1iyl:C (HIS121) to (PRO157) CRYSTAL STRUCTURE OF CANDIDA ALBICANS N-MYRISTOYLTRANSFERASE WITH NON- PEPTIDIC INHIBITOR | TRANSFERASE
2isk:A (GLU171) to (PHE194) BLUB BOUND TO FLAVIN ANION (CHARGE TRANSFER COMPLEX) | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, DITHIONITE, CHARGE TRANSFER COMPLEX, FLAVOPROTEIN
2isk:B (GLU171) to (PHE194) BLUB BOUND TO FLAVIN ANION (CHARGE TRANSFER COMPLEX) | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, DITHIONITE, CHARGE TRANSFER COMPLEX, FLAVOPROTEIN
2isk:C (GLU171) to (PHE194) BLUB BOUND TO FLAVIN ANION (CHARGE TRANSFER COMPLEX) | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, DITHIONITE, CHARGE TRANSFER COMPLEX, FLAVOPROTEIN
2isk:D (GLU171) to (PHE194) BLUB BOUND TO FLAVIN ANION (CHARGE TRANSFER COMPLEX) | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, DITHIONITE, CHARGE TRANSFER COMPLEX, FLAVOPROTEIN
2isk:E (GLU171) to (PHE194) BLUB BOUND TO FLAVIN ANION (CHARGE TRANSFER COMPLEX) | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, DITHIONITE, CHARGE TRANSFER COMPLEX, FLAVOPROTEIN
2isk:G (GLU171) to (PHE194) BLUB BOUND TO FLAVIN ANION (CHARGE TRANSFER COMPLEX) | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, DITHIONITE, CHARGE TRANSFER COMPLEX, FLAVOPROTEIN
2isk:H (GLU171) to (PHE194) BLUB BOUND TO FLAVIN ANION (CHARGE TRANSFER COMPLEX) | OXIDOREDUCTASE, FLAVIN, MONOOXYGENASE, FLAVIN DESTRUCTASE, VITAMIN B12, DITHIONITE, CHARGE TRANSFER COMPLEX, FLAVOPROTEIN
1j71:A (GLY300) to (GLN322) STRUCTURE OF THE EXTRACELLULAR ASPARTIC PROTEINASE FROM CANDIDA TROPICALIS YEAST. | CANDIDA TROPICALIS ASPARTIC PROTEASE, SAPT1, HYDROLASE
3ja6:E (LYS418) to (ASP450) CRYO-ELECTRON TOMOGRAPHY AND ALL-ATOM MOLECULAR DYNAMICS SIMULATIONS REVEAL A NOVEL KINASE CONFORMATIONAL SWITCH IN BACTERIAL CHEMOTAXIS SIGNALING | BACTERIAL CHEMOTAXIS, CORE-SIGNALING UNIT, ADAPTOR PROTEIN, HISTIDINE KINASE, CHEMORECEPTOR, SIGNALING PROTEIN
2jjj:A (GLY306) to (SER329) ENDOTHIAPEPSIN IN COMPLEX WITH A GEM-DIOL INHIBITOR. | ACID PROTEINASE, ASPARTYL PROTEASE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2jrz:A (THR9) to (LEU42) SOLUTION STRUCTURE OF THE BRIGHT/ARID DOMAIN FROM THE HUMAN JARID1C PROTEIN. | JARID1C, BRIGHT/ARID DOMAIN, HELICAL, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE
3zjf:B (LYS299) to (ASP331) A20 OTU DOMAIN WITH IRREVERSIBLY OXIDISED CYS103 FROM 270 MIN H2O2 SOAK. | HYDROLASE, UBIQUITIN, DEUBIQUITINATING ENZYME, REVERSIBLE OXIDATION, SULPHENIC ACID, CYS PROTEASE
1khu:B (SER357) to (LYS381) SMAD1 CRYSTAL STRUCTURE REVEALS THE DETAILS OF BMP SIGNALING PATHWAY | BETA-STRAND SANDWICH, TRANSCRIPTION
1khu:C (SER357) to (LYS381) SMAD1 CRYSTAL STRUCTURE REVEALS THE DETAILS OF BMP SIGNALING PATHWAY | BETA-STRAND SANDWICH, TRANSCRIPTION
3jus:B (GLU452) to (ARG500) CRYSTAL STRUCTURE OF HUMAN LANOSTEROL 14ALPHA-DEMETHYLASE (CYP51) IN COMPLEX WITH ECONAZOLE | CYTOCHROME P450, STEROL 14ALPHA-DEMETHYLASE, ECONAZOLE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, CHOLESTEROL BIOSYNTHESIS, ENDOPLASMIC RETICULUM, HEME, IRON, LIPID SYNTHESIS, MEMBRANE, METAL-BINDING, MICROSOME, MONOOXYGENASE, NADP, OXIDOREDUCTASE, STEROID BIOSYNTHESIS, STEROL BIOSYNTHESIS, TRANSMEMBRANE
2zkz:A (MSE65) to (PRO86) CRYSTAL STRUCTURE OF THE TRANSCRIPTIONAL REPRESSOR PAGR OF BACILLUS ANTHRACIS | TRANSCRIPTIONAL REPRESSOR, PROTEIN-DNA, HTH MOTIF, DIMER, DNA- BINDING, TRANSCRIPTION REGULATION, TRANSCRIPTION
2zkz:B (MSE65) to (ILE83) CRYSTAL STRUCTURE OF THE TRANSCRIPTIONAL REPRESSOR PAGR OF BACILLUS ANTHRACIS | TRANSCRIPTIONAL REPRESSOR, PROTEIN-DNA, HTH MOTIF, DIMER, DNA- BINDING, TRANSCRIPTION REGULATION, TRANSCRIPTION
2zkz:C (MSE65) to (PRO86) CRYSTAL STRUCTURE OF THE TRANSCRIPTIONAL REPRESSOR PAGR OF BACILLUS ANTHRACIS | TRANSCRIPTIONAL REPRESSOR, PROTEIN-DNA, HTH MOTIF, DIMER, DNA- BINDING, TRANSCRIPTION REGULATION, TRANSCRIPTION
3a38:A (ASP11) to (ALA76) CRYSTAL STRUCTURE OF HIGH-POTENTIAL IRON-SULFUR PROTEIN FROM THERMOCHROMATIUM TEPIDUM AT 0.7 ANGSTROM RESOLUTION | IRON-SULFUR CLUSTER, ELECTRON TRANSPORT, IRON, IRON-SULFUR, METAL- BINDING, TRANSPORT
3m0l:A (PRO55) to (THR72) CRYSTAL STRUCTURE OF PSEUDOMONAS STUTZERI L-RHAMNOSE ISOMERASE MUTANT S329F IN COMPLEX WITH D-PSICOSE | BETA/ALPHA BARREL, HOMO-TETRAMER, METAL-BINDING PROTEIN, TIM BARREL, ISOMERASE
5er2:E (GLY303) to (SER325) HIGH-RESOLUTION X-RAY DIFFRACTION STUDY OF THE COMPLEX BETWEEN ENDOTHIAPEPSIN AND AN OLIGOPEPTIDE INHIBITOR. THE ANALYSIS OF THE INHIBITOR BINDING AND DESCRIPTION OF THE RIGID BODY SHIFT IN THE ENZYME | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4bg2:A (SER163) to (PRO196) X-RAY CRYSTAL STRUCTURE OF PATF FROM PROCHLORON DIDEMNI | TRANSFERASE, PATELLAMIDE, CYANOBACTINS, NATURAL PRODUCTS, PRENYL TRANSFERASES
4bg2:B (SER163) to (PRO196) X-RAY CRYSTAL STRUCTURE OF PATF FROM PROCHLORON DIDEMNI | TRANSFERASE, PATELLAMIDE, CYANOBACTINS, NATURAL PRODUCTS, PRENYL TRANSFERASES
4r67:F (HIS20) to (GLN53) HUMAN CONSTITUTIVE 20S PROTEASOME IN COMPLEX WITH CARFILZOMIB | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4r67:T (HIS20) to (GLN53) HUMAN CONSTITUTIVE 20S PROTEASOME IN COMPLEX WITH CARFILZOMIB | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4r67:h (HIS20) to (GLN53) HUMAN CONSTITUTIVE 20S PROTEASOME IN COMPLEX WITH CARFILZOMIB | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4r67:v (HIS20) to (GLN53) HUMAN CONSTITUTIVE 20S PROTEASOME IN COMPLEX WITH CARFILZOMIB | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4c28:A (GLN425) to (ARG475) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- YLAMINO)PROPAN-2-YL)-4-(4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)- 2-FLUOROBENZAMIDE. | OXIDOREDUCTASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
4c28:B (GLY424) to (ARG475) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI CYP51 BOUND TO THE INHIBITOR (R)-N-(3-(1H-INDOL-3-YL)-1-OXO-1-(PYRIDIN-4- YLAMINO)PROPAN-2-YL)-4-(4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)- 2-FLUOROBENZAMIDE. | OXIDOREDUCTASE, STEROL BIOSYNTHESIS, CHAGAS DISEASE
5fjw:E (ASP339) to (PRO390) YEAST DELTA-COP-I MU-HOMOLOGY DOMAIN COMPLEXED WITH DSL1 WXWX(MSE) PEPTIDE | PROTEIN TRANSPORT, COP-I, VESICLE COAT PROTEIN
4rrs:A (GLY395) to (VAL417) 8-TETRAHYDROPYRAN-2-YL CHROMANS: HIGHLY SELECTIVE BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1 (BACE1) INHIBITORS | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3nxu:B (MET445) to (SER495) CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P4503A4 BOUND TO AN INHIBITOR RITONAVIR | ALPHA BETA PROTEIN, CYTOCHROME P450 FOLD, HEMOPROTEIN, MONOOXYGENASE, CYTOCHROME P450 REDUCTASE, ENDOPLASMIC RETICULUM, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
4cka:A (GLN425) to (ARG475) STEROL 14-ALPHA DEMETHYLASE (CYP51)FROM TRYPANOSOMA CRUZI IN COMPLEX WITH (S)-1-(4-FLUOROPHENYL)-2-(1H-IMIDAZOL-1-YL) ETHYL 4-ISOPROPYLPHENYLCARBAMATE (LFS) | HEME, OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM MEMBRANE
5gjq:G (HIS20) to (GLN53) STRUCTURE OF THE HUMAN 26S PROTEASOME BOUND TO USP14-UBAL | PROTEIN COMPLEX, HUMAN PROTEASOME, HYDROLASE
5gjq:h (GLN24) to (ASP58) STRUCTURE OF THE HUMAN 26S PROTEASOME BOUND TO USP14-UBAL | PROTEIN COMPLEX, HUMAN PROTEASOME, HYDROLASE
3ohf:A (GLY334) to (VAL356) CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH BMS-655295 AKA N~3~-((1S,2R)-1- BENZYL-2-HYDROXY-3-((3- METHOXYBENZYL)AMINO)PROPYL)-N~1~, N~1~-DIBUTYL-1H-INDOLE-1,3- DICARBOXAMIDE | ALZHEIMER'S DISEASE, BETA-SECRETASE, MEMAPSIN 2,ASPARTIC PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5gw5:e (GLY347) to (SER378) STRUCTURE OF TRIC-AMP-PNP | CHAPERONIN, YEAST, CHAPERONE
4uhi:A (GLY451) to (ARG500) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN C121 SPACE GROUP | OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
4uhi:C (GLY451) to (ARG500) HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN C121 SPACE GROUP | OXIDOREDUCTASE, MONOOXYGENASE, STEROL BIOSYNTHESIS, EUKARYOTIC MEMBRANES, CYTOCHROME P450 FOLD, ENDOPLASMIC RETICULUM
3pvk:A (GLY307) to (GLN329) SECRETED ASPARTIC PROTEASE 2 IN COMPLEX WITH BENZAMIDINE | HYDROLASE
4g0j:E (TRP211) to (LYS230) CRYSTALLOGRAPHIC ANALYSIS OF ROTAVIRUS NSP2-RNA COMPLEX REVEALS SPECIFIC RECOGNITION OF 5'-GG SEQUENCE FOR RTPASE ACTIVITY | RNA TRIPHOSPHATASE, RNA BINDING, HYDROLASE ACTIVITY, NUCLEOTIDE BINDING, METAL ION BINDING, HOST CELL CYTOPLASM, HYDROLASE
5p0e:A (GLY306) to (SER329) AUTOMATED REFINEMENT OF DIFFRACTION DATA OBTAINED FROM AN ENDOTHIAPEPSIN CRYSTAL TREATED WITH FRAGMENT 61 | FRAGMENT SCREENING, METHOD DEVELOPMENT, ASPARTIC PROTEASE, HYDROLASE