1n7u:A (LYS404) to (PRO433) THE RECEPTOR-BINDING PROTEIN P2 OF BACTERIOPHAGE PRD1: CRYSTAL FORM I | BACTERIOPHAGE PRD1, VIRAL RECEPTOR-BINDING, BETA-PROPELLER, PROLINE-RICH, ANTIBIOTIC-RESISTANCE, VIRAL PROTEIN
1n7v:A (LYS404) to (PRO433) THE RECEPTOR-BINDING PROTEIN P2 OF BACTERIOPHAGE PRD1: CRYSTAL FORM III | BACTERIOPHAGE PRD1, VIRAL RECEPTOR-BINDING, BETA-PROPELLER, PROLINE-RICH, ANTIBIOTIC-RESISTANCE, VIRAL PROTEIN
2obc:A (MSE128) to (LEU153) THE CRYSTAL STRUCTURE OF RIBD FROM ESCHERICHIA COLI IN COMPLEX WITH A SUBSTRATE ANALOGUE, RIBOSE 5-PHOSPHATE (BETA FORM), BOUND TO THE ACTIVE SITE OF THE REDUCTASE DOMAIN | ALPHA AND BETA CLASS OF PROTEINS WITH MAINLY PARALLELL STRANDS, SUBSTRATE ANALOGUE COMPLEX (RIBOSE 5-PHOSPHATE, BETA-FORM), STRUCTURAL GENOMICS, HTP ESCHERICHIA COLI PROTEINS, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, HYDROLASE, OXIDOREDUCTASE
1nah:A (ALA85) to (SER122) UDP-GALACTOSE 4-EPIMERASE FROM ESCHERICHIA COLI, REDUCED | ISOMERASE
1nb4:A (GLY188) to (THR221) HC-J4 RNA POLYMERASE APO-FORM | HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE
1nb6:A (GLY188) to (THR221) HC-J4 RNA POLYMERASE COMPLEXED WITH UTP | HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE
1nb6:B (MET187) to (ARG222) HC-J4 RNA POLYMERASE COMPLEXED WITH UTP | HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE
4whb:A (GLY179) to (ALA208) CRYSTAL STRUCTURE OF PHENYLUREA HYDROLASE B | AMIDOHYDROLASE, DIURON HYDROLASE, HYDROLASE
1nhu:A (GLY188) to (ARG222) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
1nhu:B (GLY188) to (ARG222) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
2okj:A (ASP196) to (PRO250) THE X-RAY CRYSTAL STRUCTURE OF THE 67KDA ISOFORM OF GLUTAMIC ACID DECARBOXYLASE (GAD67) | PLP-DEPENDENT DECARBOXYLASE, LYASE
2okk:A (MET188) to (PHE239) THE X-RAY CRYSTAL STRUCTURE OF THE 65KDA ISOFORM OF GLUTAMIC ACID DECARBOXYLASE (GAD65) | PLP-DEPENDENT DECARBOXYLASE, LYASE
4gze:E (LYS143) to (PHE178) CRYSTAL STRUCTURE OF 6-PHOSPHO-BETA-GLUCOSIDASE FROM LACTOBACILLUS PLANTARUM (APO FORM) | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, GLYCOSIDE HYDROLASE, FAMILY 1, HYDROLASE
4gzj:A (GLU85) to (GLY116) ACTIVE-SITE MUTANT OF POTATO ENDO-1,3-BETA-GLUCANASE IN COMPLEX WITH LAMINARATRIOSE AND LAMINARATETROSE | GLUCOSIDE HYDROLASE, GH17 FAMILY, PATHOGENESIS-RELATED CLASS-2 PROTEIN (PR-2), CARBOHYDRATE/SUGAR BINDING, CATALYTIC NUCLEOPHILE MUTATION, LAMINARATRIOSE, LAMINARATETROSE, TIM BARREL, HYDROLASE
2awz:A (GLY188) to (ARG222) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5H) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
2awz:B (GLY188) to (ARG222) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5H) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
2ax0:A (GLY188) to (ARG222) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5X) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
2ax0:B (GLY188) to (ARG222) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5X) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
2ax1:B (GLY188) to (ARG222) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5EE) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
4wna:D (THR119) to (SER150) STRUCTURE OF THE NITROGENASE MOFE PROTEIN FROM AZOTOBACTER VINELANDII PRESSURIZED WITH XENON | XENON, MOFE PROTEIN, NITROGENASE, SUBSTRATE ACCESS, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
2b36:A (LEU197) to (LYS233) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ENOYL REDUCTASE (INHA) INHIBITED BY 5-PENTYL-2-PHENOXYPHENOL | ENOYL REDUCTASE, OXIDOREDUCTASE
3elw:A (LEU8) to (VAL35) WESSELSBRON VIRUS METHYLTRANSFERASE IN COMPLEX WITH ADOMET AND GPPPG | FLAVIVIRUS, RNA CAPPING, METHYLTRANSFERASE, GUANYLYLTRANSFERASE, VIRAL ENZYME STRUCTURE, TRANSFERASE
3ely:A (LEU8) to (ASP36) WESSELSBRON VIRUS METHYLTRANSFERASE IN COMPLEX WITH ADOHCY | FLAVIVIRUS, RNA CAPPING, METHYLTRANSFERASE, GUANYLYLTRANSFERASE, VIRAL ENZYME STRUCTURE, TRANSFERASE
1awi:A (PRO44) to (SER76) HUMAN PLATELET PROFILIN COMPLEXED WITH THE L-PRO10 PEPTIDE | PROFILIN, POLY-L-PROLINE, ACTIN CYTOSKELETON, COMPLEX (ACTIN-BINDING PROTEIN/PEPTIDE)
4wsh:A (ASP294) to (ASN325) CRYSTAL STRUCTURE OF PROBABLE UROPORPHYRINOGEN DECARBOXYLASE (UPD) (URO-D) FROM PSEUDOMONAS AERUGINOSA | SSGCID, PSEUDOMONAS AERUGINOSA, UROPORPHYRINOGEN DECARBOXYLASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
4wsh:B (ASP294) to (ASN325) CRYSTAL STRUCTURE OF PROBABLE UROPORPHYRINOGEN DECARBOXYLASE (UPD) (URO-D) FROM PSEUDOMONAS AERUGINOSA | SSGCID, PSEUDOMONAS AERUGINOSA, UROPORPHYRINOGEN DECARBOXYLASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
2p1f:A (SER37) to (ALA69) HUMAN UMP SYNTHASE (C-TERMINAL DOMAIN-OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE) | UMP SYNTHASE, C-TERMINAL DOMAIN, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, HUMAN, HYDROLASE
2p3s:A (GLY85) to (TYR109) CRYSTAL STRUCTURE OF A THERMOSTABLE MUTANT OF BACILLUS SUBTILIS ADENYLATE KINASE (G214R/Q199R) | THERMOSTABILITY, ADENYLATE KINASE, EXPERIMENTAL ADAPTIVE EVOLUTION, DIRECTED EVOLUTION, TRANSFERASE
1o17:D (ALA161) to (PHE193) ANTHRANILATE PHOSPHORIBOSYL-TRANSFERASE (TRPD) | NUCLEOSIDE-PHOSPHORYLASES, TRANSFERASE
4wza:B (THR119) to (SER150) ASYMMETRIC NUCLEOTIDE BINDING IN THE NITROGENASE COMPLEX | NITROGENASE, NUCLEOTIDE BINDING, ASYMETRY, COMPLEX, OXIDOREDUCTASE
4wza:D (THR119) to (SER150) ASYMMETRIC NUCLEOTIDE BINDING IN THE NITROGENASE COMPLEX | NITROGENASE, NUCLEOTIDE BINDING, ASYMETRY, COMPLEX, OXIDOREDUCTASE
4wzb:D (THR119) to (SER150) CRYSTAL STRUCTURE OF MGAMPPCP-BOUND AV2-AV1 COMPLEX | NITROGEN FIXATION, IRON-SULFUR, METAL-BINDING, MOLYBDENUM, OXIDOREDUCTASE
4hgx:B (SER146) to (LEU169) CRYSTAL STRUCTURE OF XYLOSE ISOMERASE DOMAIN CONTAINING PROTEIN (STM4435) FROM SALMONELLA TYPHIMURIUM LT2 WITH UNKNOWN LIGAND | XYLOSE ISOMERASE DOMAIN, UNKNOWN LIGAND, ISOMERASE
3ewx:A (SER226) to (ALA258) K314A MUTANT OF HUMAN OROTIDYL-5'-MONOPHOSPHATE DECARBOXYLASE IN COMPLEX WITH 6-AZIDO-UMP, DEGRADED TO BMP | DECARBOXYLASE, TIM BARREL, UNUSUAL CATALYSIS, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
3ex3:A (SER226) to (ALA258) HUMAN OROTIDYL-5'-MONOPHOSPHATE DECARBOXYLASE IN COMPLEX WITH 6-AZIDO- UMP, COVALENT ADDUCT | DECARBOXYLASE, TIM BARREL, UNUSUAL CATALYSIS, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
4hhl:A (PRO97) to (GLY138) HIGH RESOLUTION CRYSTAL STRUCTURE OF GLUCOSE ISOMERASE FROM STREPTOMYCES SP. SK | TIM-BARREL, ISOMERASE
4hhm:C (PRO97) to (GLY138) CRYSTAL STRUCTURE OF A MUTANT, G219A, OF GLUCOSE ISOMERASE FROM STREPTOMYCES SP. SK | TIM-BARREL, ISOMERASE
4hhm:F (PRO97) to (GLY138) CRYSTAL STRUCTURE OF A MUTANT, G219A, OF GLUCOSE ISOMERASE FROM STREPTOMYCES SP. SK | TIM-BARREL, ISOMERASE
4hhm:G (PRO97) to (GLY138) CRYSTAL STRUCTURE OF A MUTANT, G219A, OF GLUCOSE ISOMERASE FROM STREPTOMYCES SP. SK | TIM-BARREL, ISOMERASE
2bm8:C (MET188) to (MET213) CMCI-N160 APO-STRUCTURE | CEPHAMYCIN BIOSYNTHESIS, PORIN
3s5u:A (SER72) to (ASP122) CRYSTAL STRUCTURE OF CRISPR ASSOCIATED PROTEIN | CRISPR, CRISPR ADAPTATION MECHANISM, NEW SPACER AQUISITION, DSDNA BINDING, DNA BINDING PROTEIN
2bre:A (LYS178) to (THR210) STRUCTURE OF A HSP90 INHIBITOR BOUND TO THE N-TERMINUS OF YEAST HSP90. | CHAPERONE/COMPLEX, 3D-STRUCTURE, ATP-BINDING, CHAPERONE, HEAT SHOCK, INHIBITOR, MULTIGENE FAMILY
2bre:B (LYS178) to (THR210) STRUCTURE OF A HSP90 INHIBITOR BOUND TO THE N-TERMINUS OF YEAST HSP90. | CHAPERONE/COMPLEX, 3D-STRUCTURE, ATP-BINDING, CHAPERONE, HEAT SHOCK, INHIBITOR, MULTIGENE FAMILY
4x82:B (ARG110) to (PRO156) CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF ZIP4 | ZINC TRANSPORTER, EXTRACELLULAR DOMAIN, TRANSPORT PROTEIN
1bvr:A (THR196) to (LYS233) M.TB. ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH NAD+ AND C16-FATTY- ACYL-SUBSTRATE | NADH-DEPENDENT ENOYL-ACP REDUCTASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, OXIDOREDUCTASE
1bvr:B (THR196) to (LYS233) M.TB. ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH NAD+ AND C16-FATTY- ACYL-SUBSTRATE | NADH-DEPENDENT ENOYL-ACP REDUCTASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, OXIDOREDUCTASE
1bvr:C (THR196) to (LYS233) M.TB. ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH NAD+ AND C16-FATTY- ACYL-SUBSTRATE | NADH-DEPENDENT ENOYL-ACP REDUCTASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, OXIDOREDUCTASE
1bvr:F (THR196) to (LYS233) M.TB. ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH NAD+ AND C16-FATTY- ACYL-SUBSTRATE | NADH-DEPENDENT ENOYL-ACP REDUCTASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, OXIDOREDUCTASE
4xc0:A (LYS181) to (THR212) N-TERMINAL DOMAIN OF HSP90 FROM DICTYOSTELIUM DISCOIDEUM IN COMPLEX WITH ACP | HSP90, ACP, CHAPERONE
3sbu:B (SER63) to (ASN90) CRYSTAL STRUCTURE OF A NTF2-LIKE PROTEIN (BF2862) FROM BACTEROIDES FRAGILIS NCTC 9343 AT 2.15 A RESOLUTION | CYSTATIN-LIKE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, UNKNOWN FUNCTION
3feq:B (ASN72) to (ARG104) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN EAH89906 | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, UNKNOWN FUNCTION, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3feq:C (ASN72) to (ARG104) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN EAH89906 | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, UNKNOWN FUNCTION, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3feq:F (ASN72) to (ARG104) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN EAH89906 | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, UNKNOWN FUNCTION, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3feq:G (ASN72) to (ARG104) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN EAH89906 | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, UNKNOWN FUNCTION, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3feq:H (ASN72) to (ARG104) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN EAH89906 | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, UNKNOWN FUNCTION, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3feq:I (ASN72) to (ARG104) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN EAH89906 | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, UNKNOWN FUNCTION, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3feq:J (ASN72) to (ARG104) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN EAH89906 | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, UNKNOWN FUNCTION, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3feq:K (ASN72) to (ARG104) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN EAH89906 | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, UNKNOWN FUNCTION, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3feq:L (ASN72) to (ARG104) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN EAH89906 | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, UNKNOWN FUNCTION, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3feq:M (ASN72) to (ARG104) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN EAH89906 | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, UNKNOWN FUNCTION, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3feq:N (ASN72) to (ARG104) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN EAH89906 | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, UNKNOWN FUNCTION, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3feq:O (ASN72) to (ARG104) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN EAH89906 | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, UNKNOWN FUNCTION, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
3feq:P (ASN72) to (ARG104) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN EAH89906 | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, UNKNOWN FUNCTION, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
4xcl:A (LYS181) to (THR212) N-TERMINAL DOMAIN OF HSP90 FROM DICTYOSTELIUM DISCOIDEUM IN COMPLEX WITH AGS | HSP90, AGS, CHAPERONE
1c2p:A (GLY188) to (ARG222) HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE | POLYMERASE RNA-DEPENDENT RNA POLYMERASE HEPATITIS C VIRUS NS5B APOENZYME, TRANSFERASE
1c2p:B (GLY188) to (ARG222) HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE | POLYMERASE RNA-DEPENDENT RNA POLYMERASE HEPATITIS C VIRUS NS5B APOENZYME, TRANSFERASE
4xd8:A (LYS181) to (THR212) N-TERMINAL DOMAIN OF HSP90 FROM DICTYOSTELIUM DISCOIDEUM IN COMPLEX WITH ANP | HSP90, ANP, CHAPERONE
2byh:A (LYS191) to (GLU223) 3-(5-CHLORO-2,4-DIHYDROXYPHENYL)-PYRAZOLE-4-CARBOXAMIDES AS INHIBITORS OF THE HSP90 MOLECULAR CHAPERONE | PYRAZOLE, HSP90, CHAPERONE, ATP-BINDING, HEAT SHOCK, NUCLEOTIDE-BINDING, PHOSPHORYLATION
2byi:A (LYS191) to (GLU223) 3-(5-CHLORO-2,4-DIHYDROXYPHENYL)-PYRAZOLE-4-CARBOXAMIDES AS INHIBITORS OF THE HSP90 MOLECULAR CHAPERONE | PYRAZOLE, HSP90, CHAPERONE, ATP-BINDING, HEAT SHOCK, NUCLEOTIDE-BINDING, PHOSPHORYLATION
4xe2:A (LYS181) to (THR212) N-TERMINAL DOMAIN OF HSP90 FROM DICTYOSTELIUM DISCOIDEUM IN COMPLEX WITH PEPTIDE | HSP90, ACP, CHAPERONE
3fga:C (PHE6) to (ARG49) STRUCTURAL BASIS OF PP2A AND SGO INTERACTION | PP2A, SHUGOSHIN, NUCLEUS, PHOSPHOPROTEIN, HYDROLASE, IRON, MANGANESE, METAL-BINDING, METHYLATION, PROTEIN PHOSPHATASE, CELL CYCLE, CELL DIVISION, CENTROMERE, CHROMOSOME PARTITION, MITOSIS, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4i2p:A (ARG277) to (VAL317) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH RILPIVIRINE (TMC278) BASED ANALOGUE | P51/P66, HETERO DIMER, NNRTI, NONNUCLEOSIDE INHIBITOR, AIDS, HIV, DNA RECOMBINATION, RNA-DIRECTED DNA POLYMERASE, DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MULTIFUNCTIONAL ENZYME, TRANSFERASE, TRANSFERASE-INHIBITOR COMPLEX
2c20:A (LEU79) to (SER116) CRYSTAL STRUCTURE OF UDP-GLUCOSE 4-EPIMERASE | CARBOHYDRATE METABOLISM, GALACTOSE METABOLISM, ISOMERASE, NAD, SPINE
2c20:B (VAL80) to (SER116) CRYSTAL STRUCTURE OF UDP-GLUCOSE 4-EPIMERASE | CARBOHYDRATE METABOLISM, GALACTOSE METABOLISM, ISOMERASE, NAD, SPINE
2c20:D (LEU79) to (SER116) CRYSTAL STRUCTURE OF UDP-GLUCOSE 4-EPIMERASE | CARBOHYDRATE METABOLISM, GALACTOSE METABOLISM, ISOMERASE, NAD, SPINE
2c20:E (LEU79) to (SER116) CRYSTAL STRUCTURE OF UDP-GLUCOSE 4-EPIMERASE | CARBOHYDRATE METABOLISM, GALACTOSE METABOLISM, ISOMERASE, NAD, SPINE
2c20:F (VAL80) to (SER116) CRYSTAL STRUCTURE OF UDP-GLUCOSE 4-EPIMERASE | CARBOHYDRATE METABOLISM, GALACTOSE METABOLISM, ISOMERASE, NAD, SPINE
1c8n:C (GLY221) to (GLY247) TOBACCO NECROSIS VIRUS | VIRUS, ICOSAHEDRAL VIRUS
3fjy:A (THR267) to (CYS299) CRYSTAL STRUCTURE OF A PROBABLE MUTT1 PROTEIN FROM BIFIDOBACTERIUM ADOLESCENTIS | PROBABLE MUTT1 PROTEIN, DIMER, PROTEIN STRUCTURE INITIATIVE II(PSI II), NYSGXRC, 11181H, STRUCTURAL GENOMICS, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, UNKNOWN FUNCTION, HYDROLASE
3fjy:B (THR267) to (CYS299) CRYSTAL STRUCTURE OF A PROBABLE MUTT1 PROTEIN FROM BIFIDOBACTERIUM ADOLESCENTIS | PROBABLE MUTT1 PROTEIN, DIMER, PROTEIN STRUCTURE INITIATIVE II(PSI II), NYSGXRC, 11181H, STRUCTURAL GENOMICS, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, UNKNOWN FUNCTION, HYDROLASE
1okg:A (TRP281) to (MSE306) 3-MERCAPTOPYRUVATE SULFURTRANSFERASE FROM LEISHMANIA MAJOR | MERCAPTOPYRUVATE, SULFURTRANSFERASE, RHODANESE, PROLYL ISOMERASE, CATALYTIC TRIAD, SERINE PROTEASE, LEISHMANIA PYRUVATE, TRANSFERASE
1okj:C (THR164) to (ASP182) CRYSTAL STRUCTURE OF THE ESSENTIAL E. COLI YEAZ PROTEIN BY MAD METHOD USING THE GADOLINIUM COMPLEX "DOTMA" | POTENTIAL ZINC PROTEASE, HYPOTHETICAL PROTEASE YEAZ, METALLOPROTEASE, HYDROLASE, BACTERIAL TARGETS AT IGS-CNRS, FRANCE, BIGS, STRUCTURAL GENOMICS
3ska:A (GLY188) to (ARG222) I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ska:B (GLY188) to (ARG222) I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ske:A (GLY188) to (ARG222) I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ske:B (GLY188) to (ARG222) I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1cf0:A (THR43) to (SER76) HUMAN PLATELET PROFILIN COMPLEXED WITH AN L-PRO10- IODOTYROSINE PEPTIDE | COMPLEX (ACTIN-BINDING PROTEIN/PEPTIDE), PROFILIN, POLY-L- PROLINE, ACTIN CYTOSKELETON
4xko:A (LYS181) to (GLU215) N-TERMINAL DOMAIN OF HSP90 FROM DICTYOSTELIUM DISCOIDEUM IN HEXAGONAL FORM WITH PEG | HSP90, CHAPERONE, PEG
3slc:C (CYS286) to (GLY332) CRYSTAL STRUCTURE OF APO FORM OF ACETATE KINASE (ACKA) FROM SALMONELLA TYPHIMURIUM | ACTIN-LIKE ATPASE DOMAIN, ASKHA SUPERFAMILY OF PHOSPHOTRANSFERASE, ACETOKINASE, ATP BINDING, PHOSPHOTRANSFERASE, TRANSFERASE
1ono:A (GLU126) to (ASP150) ISPC MN2+ COMPLEX | ISOPRENOID BIOSYNTHESIS, MEVALONATE-INDEPENDENT PATHWAY, ISPC, OXIDOREDUCTASE
1ono:B (GLU126) to (ASP150) ISPC MN2+ COMPLEX | ISOPRENOID BIOSYNTHESIS, MEVALONATE-INDEPENDENT PATHWAY, ISPC, OXIDOREDUCTASE
4i5l:F (ASP2) to (ARG49) STRUCTURAL MECHANISM OF TRIMERIC PP2A HOLOENZYME INVOLVING PR70: INSIGHT FOR CDC6 DEPHOSPHORYLATION | EF HAND, PHOSPHATASE, CDC6 (SUBSTRATE), HYDROLASE-TOXIN COMPLEX
3fne:A (SER200) to (LYS233) CRYSTAL STRUCTURE OF INHA BOUND TO TRICLOSAN DERIVATIVE 17 | INHA, TRICLOSAN, TUBERCULOSIS, ANTIBIOTIC RESISTANCE, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS, NAD, OXIDOREDUCTASE
3fnf:A (SER200) to (LYS233) CRYSTAL STRUCTURE OF INHA BOUND TO TRICLOSAN DERIVATIVE | INHA, TRICLOSAN, TUBERCULOSIS, ANTIBIOTIC RESISTANCE, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS, NAD, OXIDOREDUCTASE
4i5n:C (LYS4) to (ARG49) STRUCTURAL MECHANISM OF TRIMERIC PP2A HOLOENZYME INVOLVING PR70: INSIGHT FOR CDC6 DEPHOSPHORYLATION | EF HAND, PHOSPHATASE, CDC6 (SUBSTRATE), TRANSFERASE-TOXIN COMPLEX, HYDROLASE-TOXIN COMPLEX
4i5n:F (PHE6) to (ARG49) STRUCTURAL MECHANISM OF TRIMERIC PP2A HOLOENZYME INVOLVING PR70: INSIGHT FOR CDC6 DEPHOSPHORYLATION | EF HAND, PHOSPHATASE, CDC6 (SUBSTRATE), TRANSFERASE-TOXIN COMPLEX, HYDROLASE-TOXIN COMPLEX
3sms:A (ASN322) to (PHE350) HUMAN PANTOTHENATE KINASE 3 IN COMPLEX WITH A PANTOTHENATE ANALOG | STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
1cke:A (GLN94) to (ASP129) CMP KINASE FROM ESCHERICHIA COLI FREE ENZYME STRUCTURE | NUCLEOTIDE MONOPHOSPHATE KINASE,, TRANSFERASE
2c54:B (GLY104) to (ALA141) GDP-MANNOSE-3', 5' -EPIMERASE (ARABIDOPSIS THALIANA), K178R, WITH GDP-BETA-L-GULOSE AND GDP-4-KETO-BETA-L-GULOSE BOUND IN ACTIVE SITE. | 3' 5'-EPIMERASE, SHORT CHAIN DEHYDRATASE/REDUCTASE, GDP- MANNOSE, GDP-GULOSE, GDP-GALACTOSE, KETO INTERMEDIATE, VITAMIN C, SDR, ISOMERASE, ASCORBATE BIOSYNTHESIS, NAD
3fqk:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH HCV-796 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE, HCV-796
3fqk:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH HCV-796 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE, HCV-796
3fql:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B (CON1 1-570) WITH HCV-796 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE, HCV- 796
1osf:A (LYS191) to (GLU223) HUMAN HSP90 IN COMPLEX WITH 17-DESMETHOXY-17-N,N- DIMETHYLAMINOETHYLAMINO-GELDANAMYCIN | CELL CYCLE
3frz:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE IN COMPLEX WITH PF868554 | VIRAL POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3sq2:A (ASP524) to (LEU580) RB69 DNA POLYMERASE TERNARY COMPLEX WITH DTTP OPPOSITE 2AP (AT RICH SEQUENCE) | 2-AMINOPURINE, AT RICH, TRANSFERASE-DNA COMPLEX
2q2r:A (SER260) to (GLY306) TRYPANOSOMA CRUZI GLUCOKINASE IN COMPLEX WITH BETA-D-GLUCOSE AND ADP | ATPASE HEXOSE KINASE FAMILY, TRANSFERASE
2q2r:B (ALA261) to (GLY306) TRYPANOSOMA CRUZI GLUCOKINASE IN COMPLEX WITH BETA-D-GLUCOSE AND ADP | ATPASE HEXOSE KINASE FAMILY, TRANSFERASE
2q6z:A (MET174) to (GLU218) UROPORPHYRINOGEN DECARBOXYLASE G168R SINGLE MUTANT APO- ENZYME | UROPORPHYRINOGEN DECARBOXYLASE ENZYME UROD G168R COPROPORPHYRINOGEN, LYASE
4ign:F (GLU51) to (SER74) 2.32 ANGSTROM X-RAY CRYSTAL STRUCTURE OF R47A MUTANT OF HUMAN ACMSD | TIM BARREL, NEUROLOGICAL DISORDER, ZINC-DEPENDENT DECARBOXYLASE, KYNURENINE PATHWAY, LYASE
4ih5:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS | FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ih5:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS | FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ih6:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS | FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ih6:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS | FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ih7:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS | FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ih7:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS | FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1p44:B (THR196) to (LYS233) TARGETING TUBERCULOSIS AND MALARIA THROUGH INHIBITION OF ENOYL REDUCTASE: COMPOUND ACTIVITY AND STRUCTURAL DATA | INHA, SHORT CHAIN DEHYDROGENASE REDUCTASE, INHIBITOR, ROSSMANN FOLD, ENOYL-ACP REDUCTASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, OXIDOREDUCTASE
1p44:C (LEU197) to (LYS233) TARGETING TUBERCULOSIS AND MALARIA THROUGH INHIBITION OF ENOYL REDUCTASE: COMPOUND ACTIVITY AND STRUCTURAL DATA | INHA, SHORT CHAIN DEHYDROGENASE REDUCTASE, INHIBITOR, ROSSMANN FOLD, ENOYL-ACP REDUCTASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, OXIDOREDUCTASE
1p44:F (THR196) to (LYS233) TARGETING TUBERCULOSIS AND MALARIA THROUGH INHIBITION OF ENOYL REDUCTASE: COMPOUND ACTIVITY AND STRUCTURAL DATA | INHA, SHORT CHAIN DEHYDROGENASE REDUCTASE, INHIBITOR, ROSSMANN FOLD, ENOYL-ACP REDUCTASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, OXIDOREDUCTASE
1p4d:C (PRO87) to (ASN145) F FACTOR TRAI RELAXASE DOMAIN | 5-STRAND ANTIPARALLEL BETA SHEET, ALPHA-BETA, 3 HISTIDINE MG(II) COORDINATION, HYDROLASE
2qce:A (SER226) to (ALA258) CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE BOUND TO SULFATE, GLYCEROL, AND CHLORIDE | UMP SYNTHASE, DECARBOXYLASE, CATALYTIC PROFICIENCY, LYASE
2qch:B (SER226) to (ALA258) CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE BOUND TO 5-IODO-UMP | UMP SYNTHASE, DECARBOXYLASE, CATALYTIC PROFICIENCY, LYASE
2cfi:A (TYR56) to (PHE85) THE HYDROLASE DOMAIN OF HUMAN 10-FTHFD IN COMPLEX WITH 6- FORMYLTETRAHYDROPTERIN | TETRAHYDROFOLATE, FOLATE BINDING, NADP, ONE-CARBON METABOLISM, OXIDOREDUCTASE, PHOSPHOPANTETHEINE
2qe2:A (GLY188) to (ARG222) STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR | TRANSFERASE
2qe2:B (GLY188) to (ARG222) STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR | TRANSFERASE
2qe5:D (GLY188) to (ARG222) STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR | TRANSFERASE POLYMERASE
4iix:B (ALA28) to (LYS54) STRUCTURE OF MCCF IN COMPLEX WITH GLUTAMYL SULFAMOYL GUANOSINE | CARBOXYPEPTIDASE, ESG, HYDROLASE
4iiy:A (ALA28) to (LYS54) STRUCTURE OF MCCF IN COMPLEX WITH GLUTAMYL SULFAMOYL INOSINE | CARBOXYPEPTIDASE, ESI, HYDROLASE
2ch5:A (ASP209) to (GLY270) CRYSTAL STRUCTURE OF HUMAN N-ACETYLGLUCOSAMINE KINASE IN COMPLEX WITH N-ACETYLGLUCOSAMINE | TRANSFERASE, N-ACETYLGLUCOSAMINE, GLCNAC, SUGAR KINASE, RIBONUCLEASE H FOLD, SUGAR KINASE/HSP70/ACTIN SUPERFAMILY, DOMAIN ROTATION, OPEN CONFORMATION, CLOSED CONFORMATION, HYPOTHETICAL PROTEIN
2ch5:B (ASP209) to (GLY270) CRYSTAL STRUCTURE OF HUMAN N-ACETYLGLUCOSAMINE KINASE IN COMPLEX WITH N-ACETYLGLUCOSAMINE | TRANSFERASE, N-ACETYLGLUCOSAMINE, GLCNAC, SUGAR KINASE, RIBONUCLEASE H FOLD, SUGAR KINASE/HSP70/ACTIN SUPERFAMILY, DOMAIN ROTATION, OPEN CONFORMATION, CLOSED CONFORMATION, HYPOTHETICAL PROTEIN
2ch5:C (ASP209) to (GLY270) CRYSTAL STRUCTURE OF HUMAN N-ACETYLGLUCOSAMINE KINASE IN COMPLEX WITH N-ACETYLGLUCOSAMINE | TRANSFERASE, N-ACETYLGLUCOSAMINE, GLCNAC, SUGAR KINASE, RIBONUCLEASE H FOLD, SUGAR KINASE/HSP70/ACTIN SUPERFAMILY, DOMAIN ROTATION, OPEN CONFORMATION, CLOSED CONFORMATION, HYPOTHETICAL PROTEIN
3g3d:B (SER37) to (ALA69) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 5-FLUORO-6-AZIDO-UMP | UMP SYNTHASE, C-TERMINAL DOMAIN, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, HUMAN, 5-FLUORO-6-AZIDO-UMP, DECARBOXYLASE, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PHOSPHOPROTEIN, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
3g3m:A (SER37) to (ALA69) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 5-FLUORO-6-IODO-UMP | HUMAN, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, C-TERMINAL DOMAIN, 5-FLUORO-6-IODO-UMP, ALTERNATIVE SPLICING, DECARBOXYLASE, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PHOSPHOPROTEIN, POLYMORPHISM, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
2qg7:A (ASP64) to (ILE115) PLASMODIUM VIVAX ETHANOLAMINE KINASE PV091845 | MALARIA, ETHANOLAMINE KINASE, PV091845, SGC, STRUCTURAL GENOMICS CONSORTIUM, TRANSFERASE
2ckf:B (THR9) to (MET48) CRYSTAL STRUCTURE OF THE TERMINAL COMPONENT OF THE PAH- HYDROXYLATING DIOXYGENASE FROM SPHINGOMONAS SP CHY-1 | RIESKE NON HEME IRON DIOXYGENASE, PYRENE DIOXYGENASE, RING- HYDROXYLATING DIOXYGENASE, HIGH-MOLECULAR-WEIGHT POLYCYCLIC AROMATIC HYDROCARBONS, OXIDOREDUCTASE
2ckf:D (PRO10) to (MET48) CRYSTAL STRUCTURE OF THE TERMINAL COMPONENT OF THE PAH- HYDROXYLATING DIOXYGENASE FROM SPHINGOMONAS SP CHY-1 | RIESKE NON HEME IRON DIOXYGENASE, PYRENE DIOXYGENASE, RING- HYDROXYLATING DIOXYGENASE, HIGH-MOLECULAR-WEIGHT POLYCYCLIC AROMATIC HYDROCARBONS, OXIDOREDUCTASE
4xrr:B (SER275) to (VAL334) CRYSTAL STRUCTURE OF CALS8 FROM MICROMONOSPORA ECHINOSPORA (P294S MUTANT) | CALICHEAMICIN, OXIDOREDUCTASE, STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, ENZYME DISCOVERY FOR NATURAL PRODUCT BIOSYNTHESIS, NATPRO
4xsl:B (ASP74) to (LEU108) CRYSTAL STRCUTRE OF D-TAGATOSE 3-EPIMERASE C66S FROM PSEUDOMONAS CICHORII IN COMPLEX WITH GLYCEROL | EPIMERASE, ISOMERASE
4xsl:D (ASP74) to (LEU108) CRYSTAL STRCUTRE OF D-TAGATOSE 3-EPIMERASE C66S FROM PSEUDOMONAS CICHORII IN COMPLEX WITH GLYCEROL | EPIMERASE, ISOMERASE
2qjg:A (ILE41) to (HIS65) M. JANNASCHII ADH SYNTHASE COMPLEXED WITH F1,6P | BETA-ALPHA BARREL, LYASE
2qjg:F (ILE41) to (HIS65) M. JANNASCHII ADH SYNTHASE COMPLEXED WITH F1,6P | BETA-ALPHA BARREL, LYASE
2qjg:G (ILE41) to (HIS65) M. JANNASCHII ADH SYNTHASE COMPLEXED WITH F1,6P | BETA-ALPHA BARREL, LYASE
2qjg:I (ILE41) to (HIS65) M. JANNASCHII ADH SYNTHASE COMPLEXED WITH F1,6P | BETA-ALPHA BARREL, LYASE
2qjg:T (ILE41) to (HIS65) M. JANNASCHII ADH SYNTHASE COMPLEXED WITH F1,6P | BETA-ALPHA BARREL, LYASE
2qjh:D (ILE41) to (HIS65) M. JANNASCHII ADH SYNTHASE COVALENTLY BOUND TO DIHYDROXYACETONE PHOSPHATE | BETA-ALPHA BARREL, LYASE
2qjh:L (ILE41) to (HIS65) M. JANNASCHII ADH SYNTHASE COVALENTLY BOUND TO DIHYDROXYACETONE PHOSPHATE | BETA-ALPHA BARREL, LYASE
2qjh:M (ILE41) to (HIS65) M. JANNASCHII ADH SYNTHASE COVALENTLY BOUND TO DIHYDROXYACETONE PHOSPHATE | BETA-ALPHA BARREL, LYASE
2qji:Q (ILE41) to (HIS65) M. JANNASCHII ADH SYNTHASE COMPLEXED WITH DIHYDROXYACETONE PHOSPHATE AND GLYCEROL | BETA-ALPHA BARREL, LYASE
2qji:R (ILE41) to (HIS65) M. JANNASCHII ADH SYNTHASE COMPLEXED WITH DIHYDROXYACETONE PHOSPHATE AND GLYCEROL | BETA-ALPHA BARREL, LYASE
3g7p:A (LEU43) to (PRO91) CRYSTAL STRUCTURE OF A NIFX-ASSOCIATED PROTEIN OF UNKNOWN FUNCTION (AFE_1514) FROM ACIDITHIOBACILLUS FERROOXIDANS ATCC AT 2.00 A RESOLUTION | DUF 269 FAMILY PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
3g86:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH THIAZINE INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3- BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3g86:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH THIAZINE INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3- BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
1did:A (PRO96) to (GLY137) OBSERVATIONS OF REACTION INTERMEDIATES AND THE MECHANISM OF ALDOSE- KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
1did:B (PRO96) to (GLY137) OBSERVATIONS OF REACTION INTERMEDIATES AND THE MECHANISM OF ALDOSE- KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
1die:A (PRO96) to (GLY137) OBSERVATIONS OF REACTION INTERMEDIATES AND THE MECHANISM OF ALDOSE- KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
1dik:A (GLU45) to (ARG96) PYRUVATE PHOSPHATE DIKINASE | TRANSFERASE, KINASE, PHOSPHOTRANSFERASE
1pg3:A (PRO21) to (LYS54) ACETYL COA SYNTHETASE, ACETYLATED ON LYS609 | AMP-FORMING; ADENYLATE-FORMING; THIOESTER-FORMING; LYSINE ACETYLATION, LIGASE
4itl:A (LYS156) to (LEU185) CRYSTAL STRUCTURE OF LPXK FROM AQUIFEX AEOLICUS IN COMPLEX WITH AMP- PCP AT 2.1 ANGSTROM RESOLUTION | MEMBRANE PROTEIN, KINASE, LIPID A, P-LOOP, P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE, DISACCHARIDE-1-PHOSPHATE 4'- KINASE, MEMBRANE, TRANSFERASE, LIPID METABOLISM, TETRAACYLDISACCHARIDE 4'-KINASE
3gg0:A (THR274) to (ILE301) KLEBSIELLA PNEUMONIAE BLRP1 PH 9.0 MANGANESE/CY-DIGMP COMPLEX | TIM-BARREL, EAL DOMAIN, BLUF DOMAIN, HYDROLASE, SIGNALING PROTEIN
2qum:D (ASP74) to (LEU108) CRYSTAL STRUCTURE OF D-TAGATOSE 3-EPIMERASE FROM PSEUDOMONAS CICHORII WITH D-TAGATOSE | BETA/ALPHA BARREL, ISOMERASE
2qul:A (ASP74) to (LEU108) CRYSTAL STRUCTURE OF D-TAGATOSE 3-EPIMERASE FROM PSEUDOMONAS CICHORII AT 1.79 A RESOLUTION | BETA/ALPHA BARREL, ISOMERASE
2qul:D (ASP74) to (LEU108) CRYSTAL STRUCTURE OF D-TAGATOSE 3-EPIMERASE FROM PSEUDOMONAS CICHORII AT 1.79 A RESOLUTION | BETA/ALPHA BARREL, ISOMERASE
2qun:D (ASP74) to (LEU108) CRYSTAL STRUCTURE OF D-TAGATOSE 3-EPIMERASE FROM PSEUDOMONAS CICHORII IN COMPLEX WITH D-FRUCTOSE | BETA/ALPHA BARREL, ISOMERASE
4iz0:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2,4,5- TRICHLORO-N-(5-METHYL-1,2-OXAZOL-3-YL)BENZENESULFONAMIDE | HCV NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4iz0:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2,4,5- TRICHLORO-N-(5-METHYL-1,2-OXAZOL-3-YL)BENZENESULFONAMIDE | HCV NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4iz6:A (HIS130) to (LEU155) STRUCTURE OF ENTE AND ENTB, AN NRPS ADENYLATION-PCP FUSION PROTEIN WITH PSEUDO TRANSLATIONAL SYMMETRY | PSEUDO-TRANSLATIONAL SYMMETRY, ADENYLATE-FORMING ENZYMES; ANL SUPERFAMILY; NON-RIBOSOMAL PEPTIDE SYNTHETASE; ACYL CARRIER PROTEIN; NRPS ADENYLATION DOMAINS AND ACYL CARRIER PROTEIN DOMAIN, 4'PHOSPHOPANTETHEINYLATION COFACTOR 4'PP, CHIMERA PROTEIN, FUSION PROTEIN, LIGASE
4j02:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH [(1R)-5,8- DICHLORO-1-PROPYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOL-1-YL]ACETIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2qw5:B (THR90) to (PRO128) CRYSTAL STRUCTURE OF A PUTATIVE SUGAR PHOSPHATE ISOMERASE/EPIMERASE (AVA4194) FROM ANABAENA VARIABILIS ATCC 29413 AT 1.78 A RESOLUTION | PUTATIVE SUGAR PHOSPHATE ISOMERASE/EPIMERASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, ISOMERASE
1e0v:A (PRO90) to (VAL126) XYLANASE 10A FROM SREPTOMYCES LIVIDANS. CELLOBIOSYL-ENZYME INTERMEDIATE AT 1.7 A | XYLANASE, XYLAN DEGRADATION, HYDROLASE, GLYCOSYL-ENZYME INTERMEDIATE
4j04:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 4-CHLORO-2- {[(2,4,5-TRICHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j04:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 4-CHLORO-2- {[(2,4,5-TRICHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j06:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(5- BROMOTHIOPHEN-2-YL)SULFONYL]AMINO}-4-CHLOROBENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j08:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(4- METHYLPHENYL)SULFONYL]AMINO}-5-PHENOXYBENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j08:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(4- METHYLPHENYL)SULFONYL]AMINO}-5-PHENOXYBENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j0a:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(4- METHYLPHENYL)SULFONYL]AMINO}-4-PHENOXYBENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2d3u:A (GLY188) to (ARG222) X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C VIRUS, RNA-DEPENDENT RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
2d3u:B (GLY188) to (ARG222) X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C VIRUS, RNA-DEPENDENT RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
3gnw:B (GLY188) to (ARG222) HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 4C | 1,5-BENZODIAZEPINES, HEPATITIS C VIRUS, NS5B, POLYMERASE, SULFONE, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
2d3z:A (GLY188) to (ARG222) X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C VIRUS, RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
2d3z:B (GLY188) to (ARG222) X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C VIRUS, RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
4j40:A (PRO489) to (HIS533) CRYSTAL STRUCTURE OF THE DUAL-DOMAIN GGDEF-EAL MODULE OF FIMX FROM PSEUDOMONAS AERUGINOSA | EAL PHOSPHODIESTERASE, HYDROLASE, BIOFILM, C-DI-GMP EFFECTOR, C-DI- GMP
3gsz:A (GLY188) to (ARG222) STRUCTURE OF THE GENOTYPE 2B HCV POLYMERASE | POLYMERASE, HCV, TRANSFERASE
2dma:A (GLU81) to (SER126) CRYSTAL STRUCTURE OF PH1978 FROM PYROCOCCUS HORIKOSHII OT3 (FORM II) | A-ATPASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, HYDROLASE
1q74:A (GLY50) to (LEU87) THE CRYSTAL STRUCTURE OF 1D-MYO-INOSITYL 2-ACETAMIDO-2- DEOXY-ALPHA-D-GLUCOPYRANOSIDE DEACETYLASE (MSHB) | ROSSMANN FOLD, ZINC AMINOHYDROLASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC
1q74:B (GLY50) to (LEU87) THE CRYSTAL STRUCTURE OF 1D-MYO-INOSITYL 2-ACETAMIDO-2- DEOXY-ALPHA-D-GLUCOPYRANOSIDE DEACETYLASE (MSHB) | ROSSMANN FOLD, ZINC AMINOHYDROLASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC
3tla:B (ALA28) to (LYS54) MICROCIN C7 SELF IMMUNITY PROTEIN MCCF IN THE WILD TYPE APO STATE | SERINE PROTEASE, HYDROLASE
3tlc:B (ALA28) to (LYS54) MICROCIN C7 SELF IMMUNITY PROTEIN MCCF IN COMPLEX WITH MICROCIN C7 ANTIBIOTIC | SERINE PROTEASE, HYDROLASE-ANTIBIOTIC COMPLEX
3tly:A (ALA28) to (LYS54) MICROCIN C7 SELF IMMUNITY PROTEIN MCCF ACTIVE SITE MUTANT S118A/N220A/K247A IN THE APO STATE | SERINE PROTEASE, HYDROLASE
2dt1:A (SER210) to (PRO238) CRYSTAL STRUCTURE OF THE COMPLEX OF GOAT SIGNALLING PROTEIN WITH TETRASACCHARIDE AT 2.09 A RESOLUTION | SPG-40, TETRASACCHARIDE, SIGNALING PROTEIN
3gyn:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL MONOCYCLIC DIHYDROPYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION REGULATION, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3gyn:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL MONOCYCLIC DIHYDROPYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION REGULATION, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
4jjs:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 2 | LAVAL, HCV VIRUS RDRP NS5B POLYMERASE, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4jjs:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 2 | LAVAL, HCV VIRUS RDRP NS5B POLYMERASE, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2reh:D (LEU73) to (LEU131) MECHANISTIC AND STRUCTURAL ANALYSES OF THE ROLES OF ARG409 AND ASP402 IN THE REACTION OF THE FLAVOPROTEIN NITROALKANE OXIDASE | OXIDOREDUCTASE, FLAVOENZYME, NITROALKANEFAD, FLAVOPROTEIN
1ekq:A (PRO241) to (VAL269) CRYSTAL STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE IN R3 SPACE GROUP | ALPHA-BETA, TRANSFERASE
1ekq:B (PRO241) to (VAL269) CRYSTAL STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE IN R3 SPACE GROUP | ALPHA-BETA, TRANSFERASE
1qh1:B (THR117) to (SER148) NITROGENASE MOFE PROTEIN FROM KLEBSIELLA PNEUMONIAE, PHENOSAFRANIN OXIDIZED STATE | BIOLOGICAL NITROGEN FIXATION, NITROGEN METABOLISM, MOLYBDOENZYMES, ELECTRON TRANSFER, OXIDOREDUCTASE
1qh1:D (THR117) to (SER148) NITROGENASE MOFE PROTEIN FROM KLEBSIELLA PNEUMONIAE, PHENOSAFRANIN OXIDIZED STATE | BIOLOGICAL NITROGEN FIXATION, NITROGEN METABOLISM, MOLYBDOENZYMES, ELECTRON TRANSFER, OXIDOREDUCTASE
1qh8:B (THR117) to (SER148) NITROGENASE MOFE PROTEIN FROM KLEBSIELLA PNEUMONIAE, AS- CRYSTALLIZED (MIXED OXIDATION) STATE | BIOLOGICAL NITROGEN FIXATION, NITROGEN METABOLISM, MOLYBDOENZYMES, ELECTRON TRANSFER, OXIDOREDUCTASE
1qh8:D (THR117) to (SER148) NITROGENASE MOFE PROTEIN FROM KLEBSIELLA PNEUMONIAE, AS- CRYSTALLIZED (MIXED OXIDATION) STATE | BIOLOGICAL NITROGEN FIXATION, NITROGEN METABOLISM, MOLYBDOENZYMES, ELECTRON TRANSFER, OXIDOREDUCTASE
2e1z:A (ARG280) to (THR324) CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM PROPIONATE KINASE (TDCD) IN COMPLEX WITH DIADENOSINE TETRAPHOSPHATE (AP4A) OBTAINED AFTER CO-CRYSTALLIZATION WITH ATP | PROPIONATE KINASE, TDCD, NATIVE, ACETATE KINASE, NUCLEOTIDE, AP4A, ADP, ATP, AMPPNP, TRANSFERASE
2e20:A (LEU279) to (THR324) CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM PROPIONATE KINASE (TDCD) IN COMPLEX WITH DIADENOSINE TETRAPHOSPHATE (AP4A) | PROPIONATE KINASE, TDCD, NATIVE, ACETATE KINASE, NUCLEOTIDE, AP4A, ADP, ATP, AMPPNP, TRANSFERASE
3h2l:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH A NOVEL BICYCLIC DIHYDRO-PYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, HEPATITIS C, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING
3h2l:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH A NOVEL BICYCLIC DIHYDRO-PYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, HEPATITIS C, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING
2e2n:A (GLY247) to (LEU272) CRYSTAL STRUCTURE OF SULFOLOBUS TOKODAII HEXOKINASE IN THE APO FORM | ACETATE AND SUGAR KINASES, HSP70, ACTIN SUPERFAMILY, TRANSFERASE
2e2p:A (ALA202) to (GLY247) CRYSTAL STRUCTURE OF SULFOLOBUS TOKODAII HEXOKINASE IN COMPLEX WITH ADP | ACETATE AND SUGAR KINASES/HSP70/ACTIN SUPERFAMILY, RIBONUCLEASE-H FOLD, SUGAR KINASE, GLUCOSE, N- ACETYLGLUCOSAMINE,HEXOKINASE, CONFORMATIONAL CHANGE, PHOSPHORYL TRANSFER, TRANSFERASE
2e2p:A (GLY247) to (LEU272) CRYSTAL STRUCTURE OF SULFOLOBUS TOKODAII HEXOKINASE IN COMPLEX WITH ADP | ACETATE AND SUGAR KINASES/HSP70/ACTIN SUPERFAMILY, RIBONUCLEASE-H FOLD, SUGAR KINASE, GLUCOSE, N- ACETYLGLUCOSAMINE,HEXOKINASE, CONFORMATIONAL CHANGE, PHOSPHORYL TRANSFER, TRANSFERASE
2e2q:A (GLY247) to (LEU272) CRYSTAL STRUCTURE OF SULFOLOBUS TOKODAII HEXOKINASE IN COMPLEX WITH XYLOSE, MG2+, AND ADP | ACETATE AND SUGAR KINASES/HSP70/ACTIN SUPERFAMILY, RIBONUCLEASE-H FOLD, SUGAR KINASE, GLUCOSE, N- ACETYLGLUCOSAMINE,HEXOKINASE, CONFORMATIONAL CHANGE, PHOSPHORYL TRANSFER, TRANSFERASE
3h59:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B WITH THIAZINE INHIBITOR 2 | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3h59:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B WITH THIAZINE INHIBITOR 2 | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3tyv:A (GLY188) to (ARG222) SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3tyv:B (GLY188) to (ARG222) SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h64:D (THR187) to (GLU233) CATALYTIC DOMAIN OF HUMAN SERINE/THREONINE PHOSPHATASE 5 (PP5C) WITH TWO MN2+ ATOMS COMPLEXED WITH ENDOTHALL | METALLOENZYME, PHOSPHATASE, INHIBITORS, DRUG DESIGN, CYTOPLASM, HYDROLASE, IRON, MANGANESE, METAL-BINDING, NUCLEUS, PROTEIN PHOSPHATASE, TPR REPEAT
3h66:B (THR187) to (THR230) CATALYTIC DOMAIN OF HUMAN SERINE/THREONINE PHOSPHATASE 5 (PP5C) WITH TWO ZN2+ ATOMS | METALLOENZYME, PHOSPHATASE, CYTOPLASM, HYDROLASE, IRON, MANGANESE, METAL-BINDING, NUCLEUS, PROTEIN PHOSPHATASE, TPR REPEAT
2e67:A (GLY129) to (PRO154) CRYSTAL STRUCTURE OF THE HYPOTHETICAL PROTEIN TTHB029 FROM THERMUS THERMOPHILUS HB8 | HYPOTHETICAL PROTEIN, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, STRUCTURAL GENOMICS, UNKNOWN FUNCTION, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
1quv:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE RNA DIRECTED RNA POLYMERASE OF HEPATITIS C VIRUS | RNA DEPENDENT RNA POLYMERASE, REPLICASE, HCV, NS5B, TRANSFERASE
3h86:A (ASP55) to (THR91) CRYSTAL STRUCTURE OF ADENYLATE KINASE FROM METHANOCOCCUS MARIPALUDIS | MESOPHILE, KINASE, ADENYLATE KINASE, PHOSPHOTRANSFERASE, ATP-BINDING, CYTOPLASM, NUCLEOTIDE-BINDING, TRANSFERASE
3h86:C (ASP55) to (THR91) CRYSTAL STRUCTURE OF ADENYLATE KINASE FROM METHANOCOCCUS MARIPALUDIS | MESOPHILE, KINASE, ADENYLATE KINASE, PHOSPHOTRANSFERASE, ATP-BINDING, CYTOPLASM, NUCLEOTIDE-BINDING, TRANSFERASE
3h98:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B 1B WITH (1,1-DIOXO-2H-[1,2, 4]BENZOTHIADIAZIN-3-YL) AZOLO[1,5-A]PYRIMIDINE DERIVATIVE | RNA POLYMERASE, NUCLEOTIDE BINDING, TRANSFERASE
3h98:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B 1B WITH (1,1-DIOXO-2H-[1,2, 4]BENZOTHIADIAZIN-3-YL) AZOLO[1,5-A]PYRIMIDINE DERIVATIVE | RNA POLYMERASE, NUCLEOTIDE BINDING, TRANSFERASE
4jtw:A (MET187) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COUPOUND 1 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jty:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH COMPOUND 2 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju3:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 8 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju3:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 8 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju4:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 22 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju6:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 24 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju6:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 24 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju7:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 24 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ju7:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 24 | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3u4r:B (MET187) to (ARG222) NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE C2 ACYL SULFONAMIDES | NUCLEOTIDYL TRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3u67:A (LYS176) to (LYS209) CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HSP90 FROM LEISHMANIA MAJOR(LMJF33.0312)IN COMPLEX WITH ADP | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, ATPASE, CHAPERONE, ATP BINDING
2ux0:C (SER385) to (GLU430) STRUCTURE OF THE OLIGOMERISATION DOMAIN OF CALCIUM- CALMODULIN DEPENDENT PROTEIN KINASE II GAMMA | TRANSFERASE, CALMODULIN, PROTEIN KINASE, OLIGOMERISATION DOMAIN, SERINE- THREONINE KINASE, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE.
4jy1:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 5 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1fez:B (THR214) to (GLU247) THE CRYSTAL STRUCTURE OF BACILLUS CEREUS PHOSPHONOACETALDEHYDE HYDROLASE COMPLEXED WITH TUNGSTATE, A PRODUCT ANALOG | HAD-FAMILY ALPHA/BETA CORE DOMAIN, MG(II) BINDING SITE, 5- HELIX BUNDLE, HYDROLASE
1fez:D (THR214) to (GLU247) THE CRYSTAL STRUCTURE OF BACILLUS CEREUS PHOSPHONOACETALDEHYDE HYDROLASE COMPLEXED WITH TUNGSTATE, A PRODUCT ANALOG | HAD-FAMILY ALPHA/BETA CORE DOMAIN, MG(II) BINDING SITE, 5- HELIX BUNDLE, HYDROLASE
1r3t:A (ASP54) to (ILE83) UROPORPHYRINOGEN DECARBOXYLASE SINGLE MUTANT D86G IN COMPLEX WITH COPROPORPHYRINOGEN-III | UROPORPHYRINOGEN DECARBOXYLASE COPROPORPHYRINOGEN; X-RAY CRYSTALLOGRAPHY, LYASE
4k0e:C (ARG4) to (ALA38) X-RAY CRYSTAL STRUCTURE OF A HEAVY METAL EFFLUX PUMP, CRYSTAL FORM II | STRUCTURAL GENOMICS, PSI-BIOLOGY, CENTER FOR STRUCTURES OF MEMBRANE PROTEINS, CSMP, RESISTANCE-NODULATION-CELL DIVISION (RND) SUPERFAMILY, HEAVY METAL EFFLUX PUMP, ZNEB, ZNEC, INNER MEMBRANE, TRANSPORT PROTEIN
3hgu:B (ARG169) to (ARG204) STRUCTURE OF PHENAZINE ANTIBIOTIC BIOSYNTHESIS PROTEIN | PHENAZINE, ANTIBIOTIC, BIOSYNTHETIC PROTEIN
3hgv:B (PRO168) to (ARG204) STRUCTURE OF PHENAZINE ANTIBIOTIC BIOSYNTHESIS PROTEIN | PHENAZINE, ANTIBIOTIC, BIOSYNTHETIC PROTEIN
3hhk:A (GLY188) to (ARG222) HCV NS5B POLYMERASE COMPLEX WITH A SUBSTITUTED BENZOTHIADIZINE | NS5B, POLYMERASE, HCV, INHHIBITOR, ATP-BINDING, ENVELOPE PROTEIN, HELICASE, HYDROLASE, MEMBRANE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3hhk:B (GLY188) to (ARG222) HCV NS5B POLYMERASE COMPLEX WITH A SUBSTITUTED BENZOTHIADIZINE | NS5B, POLYMERASE, HCV, INHHIBITOR, ATP-BINDING, ENVELOPE PROTEIN, HELICASE, HYDROLASE, MEMBRANE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2epg:A (VAL256) to (ASN329) CRYSTAL STRUCTURE OF TTHA1785 | ALPHA-BETA FOLD, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LIGASE
2epn:A (ILE179) to (GLY221) N-ACETYL-B-D-GLUCOSAMINIDASE (GCNA) FROM STREPTOCOCCUS GORDONII | GLYCOSIDE HYDROLASE, FAMILY 20, GLUCOSAMINIDASE, GCNA, HYDROLASE
2v30:B (SER226) to (ALA258) HUMAN OROTIDINE 5'-PHOSPHATE DECARBOXYLASE DOMAIN OF URIDINE MONOPHOSPATE SYNTHETASE (UMPS) IN COMPLEX WITH ITS PRODUCT UMP. | ALTERNATIVE SPLICING, PYRIMIDINE METABOLISM, DISEASE MUTATION, GLYCOSYLTRANSFERASE, UMP, LYASE, TRANSFERASE, POLYMORPHISM, DECARBOXYLASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS
3udl:D (GLY188) to (ARG222) 3-HETEROCYCLYL QUINOLONE BOUND TO HCV NS5B | HCV, POLYMERASE, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2eu8:B (GLY85) to (ASP116) CRYSTAL STRUCTURE OF A THERMOSTABLE MUTANT OF BACILLUS SUBTILIS ADENYLATE KINASE (Q199R) | ADENYLATE KINASE, THERMOSTABILITY, POINT MUTANT, IN VIVO EVOLUTION, TRANSFERASE
3hkw:A (GLY188) to (ARG222) HCV NS5B GENOTYPE 1A IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 6 | HCV POLYMERASE, SUBTYPE 1A, 1,5-BENZODIAZEPINE, TRANSFERASE
3hky:A (GLY188) to (ARG222) HCV NS5B POLYMERASE GENOTYPE 1B IN COMPLEX WITH 1,5 BENZODIAZEPINE 6 | HEPATITIS C VIRUS, 1,5-BENZODIAZEPINE, GENOTYPE, NS5B, POLYMERASE, BIACORE, REPLICON, TRANSFERASE
4yts:A (ASP74) to (LEU108) CRYSTAL STRUCTURE OF D-TAGATOSE 3-EPIMERASE C66S FROM PSEUDOMONAS CICHORII IN COMPLEX WITH 1-DEOXY 3-KETO D-GALACTITOL | EPIMERASE, ISOMERASE
4yts:D (ASP74) to (LEU108) CRYSTAL STRUCTURE OF D-TAGATOSE 3-EPIMERASE C66S FROM PSEUDOMONAS CICHORII IN COMPLEX WITH 1-DEOXY 3-KETO D-GALACTITOL | EPIMERASE, ISOMERASE
4ytt:D (ASP74) to (LEU108) CRYSTAL STRUCTURE OF D-TAGATOSE 3-EPIMERASE C66S FROM PSEUDOMONAS CICHORII IN COMPLEX WITH 6-DEOXY L-PSICOSE | EPIMERASE, ISOMERASE
1rdf:A (THR214) to (GLU247) G50P MUTANT OF PHOSPHONOACETALDEHYDE HYDROLASE IN COMPLEX WITH SUBSTRATE ANALOGUE VINYL SULFONATE | HALOACID DEHALOGENASE, SPECIFICITY LOOP, PHOSPHONATASE, SCHIFF-BASE, HYDROLASE
1rdf:B (THR214) to (GLU247) G50P MUTANT OF PHOSPHONOACETALDEHYDE HYDROLASE IN COMPLEX WITH SUBSTRATE ANALOGUE VINYL SULFONATE | HALOACID DEHALOGENASE, SPECIFICITY LOOP, PHOSPHONATASE, SCHIFF-BASE, HYDROLASE
1rdf:D (THR214) to (GLU247) G50P MUTANT OF PHOSPHONOACETALDEHYDE HYDROLASE IN COMPLEX WITH SUBSTRATE ANALOGUE VINYL SULFONATE | HALOACID DEHALOGENASE, SPECIFICITY LOOP, PHOSPHONATASE, SCHIFF-BASE, HYDROLASE
1rdf:E (THR214) to (GLU247) G50P MUTANT OF PHOSPHONOACETALDEHYDE HYDROLASE IN COMPLEX WITH SUBSTRATE ANALOGUE VINYL SULFONATE | HALOACID DEHALOGENASE, SPECIFICITY LOOP, PHOSPHONATASE, SCHIFF-BASE, HYDROLASE
2f1r:A (SER78) to (GLU102) CRYSTAL STRUCTURE OF MOLYBDOPTERIN-GUANINE BIOSYNTHESIS PROTEIN B (MOBB) | MOLYBDOPTERIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, BIOSYNTHETIC PROTEIN
2f1r:B (SER78) to (GLU102) CRYSTAL STRUCTURE OF MOLYBDOPTERIN-GUANINE BIOSYNTHESIS PROTEIN B (MOBB) | MOLYBDOPTERIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, BIOSYNTHETIC PROTEIN
1rh9:A (GLY93) to (VAL132) FAMILY GH5 ENDO-BETA-MANNANASE FROM LYCOPERSICON ESCULENTUM (TOMATO) | ENDO-BETA-MANNASE, RETAINING, GLYCOSIDE HYDROLASE FAMILY 5, MANNAN
2f22:A (PRO21) to (PRO62) CRYSTAL STRUCTURE OF A PUTATIVE DNA DAMAGE-INDUCABLE (DINB) PROTEIN (BH3987) FROM BACILLUS HALODURANS AT 1.42 A RESOLUTION | PUTATIVE DNA DAMAGE-INDUCABLE (DINB) PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, METAL BINDING PROTEIN
2f22:B (THR3) to (PRO62) CRYSTAL STRUCTURE OF A PUTATIVE DNA DAMAGE-INDUCABLE (DINB) PROTEIN (BH3987) FROM BACILLUS HALODURANS AT 1.42 A RESOLUTION | PUTATIVE DNA DAMAGE-INDUCABLE (DINB) PROTEIN, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, METAL BINDING PROTEIN
4kai:A (GLY188) to (ARG222) HCV NS5B GT1B N316 WITH GSK5852A | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, RNA DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, REPLICATION- REPLICATION INHIBITOR COMPLEX
4kai:B (GLY188) to (ARG222) HCV NS5B GT1B N316 WITH GSK5852A | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, RNA DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, REPLICATION- REPLICATION INHIBITOR COMPLEX
4kb7:A (GLY188) to (ARG222) HCV NS5B GT1B N316Y WITH CMPD 32 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, RNA-DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX
4kb7:B (GLY188) to (ARG222) HCV NS5B GT1B N316Y WITH CMPD 32 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, RNA-DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX
4kbi:A (GLY188) to (ARG222) HCV NS5B GT1B N316Y WITH CMPD 4 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, POLYMERASE, RNA DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX
4kbi:B (GLY188) to (ARG222) HCV NS5B GT1B N316Y WITH CMPD 4 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, POLYMERASE, RNA DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX
2f6r:A (LYS129) to (ASP175) CRYSTAL STRUCTURE OF BIFUNCTIONAL COENZYME A SYNTHASE (COA SYNTHASE): (18044849) FROM MUS MUSCULUS AT 1.70 A RESOLUTION | 18044849, BIFUNCTIONAL COENZYME A SYNTHASE (COA SYNTHASE), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI, TRANSFERASE
1rql:B (THR214) to (GLU247) CRYSTAL STRUCTURE OF PHOSPONOACETALDEHYDE HYDROLASE COMPLEXED WITH MAGNESIUM AND THE INHIBITOR VINYL SULFONATE | SCHIFF-BASE FORMATION; ACID/BASE CATALYSIS; STRUCTURAL ENZYMOLOGY; HAD SUPERFAMILY, HYDROLASE
1rqn:B (THR214) to (GLU247) PHOSPHONOACETALDEHYDE HYDROLASE COMPLEXED WITH MAGNESIUM | SCHIFF-BASE FORMATION; ACID/BASE CATALYSIS; STRUCTURAL ENZYMOLOGY; HAD SUPERFAMILY, HYDROLASE
4ke5:A (GLY188) to (ARG222) HCV NS5B GT1B N316Y WITH GSK5852 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, POLYMERASE, RNA REPLICATION, REPLICATION- REPLICATION INHIBITOR COMPLEX
4ke5:B (GLY188) to (ARG222) HCV NS5B GT1B N316Y WITH GSK5852 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, POLYMERASE, RNA REPLICATION, REPLICATION- REPLICATION INHIBITOR COMPLEX
1rtj:B (ARG358) to (LYS390) MECHANISM OF INHIBITION OF HIV-1 REVERSE TRANSCRIPTASE BY NON-NUCLEOSIDE INHIBITORS | HIV-1 REVERSE TRANSCRIPTASE, NUCLEOTIDYLTRANSFERASE
2fem:A (GLN94) to (ASP129) MUTANT R188M OF THE CYTIDINE MONOPHOSPHATE KINASE FROM E. COLI | NUCLEOTIDE MONOPHOSPHATE KINASE; TRANSFERASE, SIGNALING PROTEIN,TRANSFERASE
4khm:A (GLY188) to (ARG222) HCV NS5B GT1A WITH GSK5852 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DEPENDENT RNA POLYMERASE, RNA DIRECTED RNA POLYMERASE, REPLICATION- REPLICATION INHIBITOR COMPLEX
4khm:B (GLY188) to (ARG222) HCV NS5B GT1A WITH GSK5852 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DEPENDENT RNA POLYMERASE, RNA DIRECTED RNA POLYMERASE, REPLICATION- REPLICATION INHIBITOR COMPLEX
3uph:A (GLY188) to (ARG222) SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3uph:B (GLY188) to (ARG222) SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3upi:A (GLY188) to (ARG222) SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3upi:B (GLY188) to (ARG222) SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1g99:B (PHE284) to (THR329) AN ANCIENT ENZYME: ACETATE KINASE FROM METHANOSARCINA THERMOPHILA | ALPHA/BETA; ASKHA (ACETATE AND SUGAR KINASES, HSC70, ACTIN) SUPERFAMILY; CONSERVED EPSILON CONFORMATION; TWO SIMILAR DOMAINS, TRANSFERASE
2vhj:A (ASP6) to (GLY50) P4 PROTEIN FROM BACTERIOPHAGE PHI12 S252A MUTANT IN COMPLEX WITH ADP | NON- HYDROLYSABLE ATP ANALOGUE, HYDROLASE, VIRUS DSRNA, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE
2vhu:A (ASP6) to (GLY50) P4 PROTEIN FROM BACTERIOPHAGE PHI12 K241C MUTANT IN COMPLEX WITH ADP AND MGCL | VIRUS DSRNA, HYDROLASE, MOLECULAR MOTOR, PACKAGING ATPASE, HEXAMERIC HELICASE, NON-HYDROLYSABLE ATP ANALOGUE
4z7k:B (ASN128) to (ILE171) CRYSTAL STRUCTURE OF CRISPR RNA PROCESSING ENDORIBONUCLEASE CAS6B | CAS6, ENDORIBONUCLEASE, CRISPR RNA, HYDROLASE-RNA-DNA COMPLEX
4z7l:H (ALA126) to (LYS170) CRYSTAL STRUCTURE OF CAS6B | CRISPR RNA, ENDORIBONUCLEASES, HYDROLASE-RNA COMPLEX
2vkh:C (GLU249) to (ASP286) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF LETHAL TOXIN FROM CLOSTRIDIUM SORDELLII IN COMPLEX WITH UDP-GLC AND CALCIUM ION | TOXIN, GLYCOSYLTRANSFERASE
1s5n:A (PRO96) to (GLY137) XYLOSE ISOMERASE IN SUBSTRATE AND INHIBITOR MICHAELIS STATES: ATOMIC RESOLUTION STUDIES OF A METAL-MEDIATED HYDRIDE SHIFT | XYLOSE ISOMERASE, HYDRIDE SHIFT, ATOMIC RESOLUTION, TIM BARREL, ISOMERASE
2fvc:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF NS5B BK STRAIN (DELTA 24) IN COMPLEX WITH A 3-(1, 1-DIOXO-2H-(1,2,4)-BENZOTHIADIAZIN-3-YL)-4-HYDROXY-2(1H)-QUINOLINONE | HCV POLYMERASE, THIADIAZIN INHIBITOR, TRANSFERASE
2fvc:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF NS5B BK STRAIN (DELTA 24) IN COMPLEX WITH A 3-(1, 1-DIOXO-2H-(1,2,4)-BENZOTHIADIAZIN-3-YL)-4-HYDROXY-2(1H)-QUINOLINONE | HCV POLYMERASE, THIADIAZIN INHIBITOR, TRANSFERASE
2vl8:C (GLU249) to (ASP286) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF LETHAL TOXIN FROM CLOSTRIDIUM SORDELLII IN COMPLEX WITH UDP, CASTANOSPERMINE AND CALCIUM ION | TOXIN, GLYCOSYLTRANSFERASE
3v4y:C (LEU9) to (GLU56) CRYSTAL STRUCTURE OF THE FIRST NUCLEAR PP1 HOLOENZYME | PP1, SER/THR PHOSPHATASE, NIPP1, IDP, HYDROLASE
3v4y:G (GLY-5) to (GLU56) CRYSTAL STRUCTURE OF THE FIRST NUCLEAR PP1 HOLOENZYME | PP1, SER/THR PHOSPHATASE, NIPP1, IDP, HYDROLASE
3i16:D (SER57) to (ARG93) CRYSTAL STRUCTURE OF CARBON-SULFUR LYASE INVOLVED IN ALUMINUM RESISTANCE (YP_878183.1) FROM CLOSTRIDIUM NOVYI NT AT 2.00 A RESOLUTION | YP_878183.1, CARBON-SULFUR LYASE INVOLVED IN ALUMINUM RESISTANCE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
4kt8:A (SER5) to (PHE33) THE COMPLEX STRUCTURE OF RV3378C-Y51FY90F WITH SUBSTRATE, TPP | DITERPENE SYNTHASE, HYDROLASE
4zhr:B (LYS358) to (LYS390) STRUCTURE OF HIV-1 RT Q151M MUTANT | HIV-1 REVERSE TRANSCRIPTASE, CLOSED CONFORMATION, Q151M, TRANSFERASE
2g6v:A (MSE128) to (SER156) THE CRYSTAL STRUCTURE OF RIBD FROM ESCHERICHIA COLI | RIBD APO STRUCTURE, STRUCTURAL GENOMICS, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, HYDROLASE, OXIDOREDUCTASE
2g6v:B (MSE128) to (LEU153) THE CRYSTAL STRUCTURE OF RIBD FROM ESCHERICHIA COLI | RIBD APO STRUCTURE, STRUCTURAL GENOMICS, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, HYDROLASE, OXIDOREDUCTASE
1gx5:A (GLY188) to (ARG222) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH GTP AND MANGANESE | TRANSFERASE, POLYPROTEIN, GLYCOPROTEIN, RNA-DIRECTED RNA POLYMERASE, CORE PROTEIN, COAT PROTEIN, ENVELOPE PROTEIN, HELICASE, ATP BINDING, TRANSMEMBRANE, NONSTRUCTURAL PROTEIN
1gx6:A (GLY188) to (THR221) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH UTP AND MANGANESE | POLYMERASE, RNA-DEPENDENT RNA POLYMERASE, VIRUS REPLICATION, INITIATION, POLYPROTEIN, GLYCOPROTEIN, TRANSFERASE, RNA-DIRECTED RNA POLYMERASE
2gc8:A (GLY188) to (ARG222) STRUCTURE OF A PROLINE SULFONAMIDE INHIBITOR BOUND TO HCV NS5B POLYMERASE | TRANSFERASE
2gc8:B (GLY188) to (ARG222) STRUCTURE OF A PROLINE SULFONAMIDE INHIBITOR BOUND TO HCV NS5B POLYMERASE | TRANSFERASE
1swv:B (THR214) to (GLU247) CRYSTAL STRUCTURE OF THE D12A MUTANT OF PHOSPHONOACETALDEHYDE HYDROLASE COMPLEXED WITH MAGNESIUM | HAD ENZYME SUPERFAMILY, PHOSPHONOTASE, PHOSPHONOACETALDEHYDE, METAL BINDING, HYDROLASE
1sww:B (THR214) to (GLU247) CRYSTAL STRUCTURE OF THE PHOSPHONOACETALDEHYDE HYDROLASE D12A MUTANT COMPLEXED WITH MAGNESIUM AND SUBSTRATE PHOSPHONOACETALDEHYDE | PHOPSHONOACETALDEHYDE HYDROLASE, PHOSPHONATASE, HAD ENZYM SUPERFAMILY, METAL BINDING
2gey:A (SER2) to (GLU38) CRYSTAL STRUCTURE OF ACLR A PUTATIVE HYDROXYLASE FROM STREPTOMYCES GALILAEUS | ALPHA+BETA BARREL, OXIDOREDUCTASE
2gey:B (SER2) to (GLU38) CRYSTAL STRUCTURE OF ACLR A PUTATIVE HYDROXYLASE FROM STREPTOMYCES GALILAEUS | ALPHA+BETA BARREL, OXIDOREDUCTASE
2gey:C (SER2) to (GLU38) CRYSTAL STRUCTURE OF ACLR A PUTATIVE HYDROXYLASE FROM STREPTOMYCES GALILAEUS | ALPHA+BETA BARREL, OXIDOREDUCTASE
2gey:D (SER2) to (GLU38) CRYSTAL STRUCTURE OF ACLR A PUTATIVE HYDROXYLASE FROM STREPTOMYCES GALILAEUS | ALPHA+BETA BARREL, OXIDOREDUCTASE
3vgs:A (LYS11) to (LEU40) WILD-TYPE NUCLEOSIDE DIPHOSPHATE KINASE DERIVED FROM HALOMONAS SP. 593 | HALOPHILIC, KINASE, FERREDOXIN FOLD, ATP-BINDING, NUCLEOTIDE-BINDING, TRANSFERASE
1h1l:D (THR117) to (SER148) NITROGENASE MO-FE PROTEIN FROM KLEBSIELLA PNEUMONIAE, NIFV MUTANT | BIOLOGICAL NITROGEN FIXATION, NITROGEN METABOLISM, MOLYBDOENZYMES, ELECTRON TRANSFER, OXIDOREDUCTASE
3vhc:A (LYS191) to (GLU223) HSP90 ALPHA N-TERMINAL DOMAIN IN COMPLEX WITH A MACROCYCLIC INHIBITOR | CHAPERONE-CHAPERONE INHIBITOR COMPLEX
2giq:A (GLY188) to (ARG222) HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B WITH NNI-2 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE
2giq:B (GLY188) to (ARG222) HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B WITH NNI-2 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE
2gir:A (GLY188) to (ARG222) HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B WITH NNI-1 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE
2gir:B (GLY188) to (ARG222) HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B WITH NNI-1 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE
1t3h:B (ARG67) to (VAL111) X-RAY STRUCTURE OF DEPHOSPHO-COA KINASE FROM E. COLI NORTEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER57 | STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, TRANSFERASE
1t45:A (LYS685) to (ASP792) STRUCTURAL BASIS FOR THE AUTOINHIBITION AND STI-571 INHIBITION OF C- KIT TYROSINE KINASE | KINASE, AUTOINHIBITION,, TRANSFERASE ACTIVATOR
4zo4:A (ARG68) to (GLU114) DEPHOSPHO-COA KINASE FROM CAMPYLOBACTER JEJUNI. | STRUCTURAL GENOMICS, IDP00325, DEPHOSPHO-COA KINASE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
4zo4:B (ARG68) to (GLU114) DEPHOSPHO-COA KINASE FROM CAMPYLOBACTER JEJUNI. | STRUCTURAL GENOMICS, IDP00325, DEPHOSPHO-COA KINASE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
4zo4:C (ARG68) to (PRO116) DEPHOSPHO-COA KINASE FROM CAMPYLOBACTER JEJUNI. | STRUCTURAL GENOMICS, IDP00325, DEPHOSPHO-COA KINASE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
4zo4:D (ARG68) to (GLU114) DEPHOSPHO-COA KINASE FROM CAMPYLOBACTER JEJUNI. | STRUCTURAL GENOMICS, IDP00325, DEPHOSPHO-COA KINASE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
2w1z:A (ASN363) to (ASP409) ROP2 FROM TOXOPLASMA GONDII: A VIRULENCE FACTOR WITH A PROTEIN-KINASE FOLD AND NO ENZYMATIC ACTIVITY. | INACTIVITY, PROTEIN-KINASE, MEMBRANE-ATTACHMENT, TRANSFERASE
2w27:A (LEU47) to (ASN88) CRYSTAL STRUCTURE OF THE BACILLUS SUBTILIS YKUI PROTEIN, WITH AN EAL DOMAIN, IN COMPLEX WITH SUBSTRATE C-DI-GMP AND CALCIUM | PROTEIN STRUCTURE INITIATIVE, SIGNALING PROTEIN, STRUCTURAL GENOMICS, PSI, MCSG, EAL DOMAIN, YKUI PROTEIN, CYCLIC DI-GMP
2w27:B (LEU47) to (ASN88) CRYSTAL STRUCTURE OF THE BACILLUS SUBTILIS YKUI PROTEIN, WITH AN EAL DOMAIN, IN COMPLEX WITH SUBSTRATE C-DI-GMP AND CALCIUM | PROTEIN STRUCTURE INITIATIVE, SIGNALING PROTEIN, STRUCTURAL GENOMICS, PSI, MCSG, EAL DOMAIN, YKUI PROTEIN, CYCLIC DI-GMP
3igv:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL MONOCYCLIC DIHYDRO-PYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, HYDROLASE, ANTIVIRAL, METAL BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, ATP-BINDING, DISULFIDE BOND, HOST-VIRUS INTERACTION, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3igv:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL MONOCYCLIC DIHYDRO-PYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, HYDROLASE, ANTIVIRAL, METAL BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, ATP-BINDING, DISULFIDE BOND, HOST-VIRUS INTERACTION, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
4l93:B (LYS191) to (GLU223) CRYSTAL STRUCTURE OF HUMAN HSP90 WITH S36 | ATP HYDROLYSIS, HSP90N-HSP90N INHIBITOR COMPLEX, CHAPERONE-CHAPERONE INHIBITOR COMPLEX
4zsg:A (ASN88) to (PRO123) MITOGEN ACTIVATED PROTEIN KINASE 7 IN COMPLEX WITH INHIBITOR | KINASE, INHIBITOR
4zsj:A (ASN88) to (PRO123) MITOGEN ACTIVATED PROTEIN KINASE 7 IN COMPLEX WITH INHIBITOR | KINASE, INHIBITOR, TRANSFERASE
4zst:A (PRO135) to (THR173) CRYSTAL STRUCTURE OF BREVUNDIMONAS DIMINUTA PHOSPHOTRIESTERASE MUTANT L7EP-3A | BACTERIAL PROTEINS, ENZYMES, CATALYSIS, AMIDOHYDROLASE, CHEMICAL WARFARE AGENTS, VX NERVE AGENT, VR NERVE AGENT, HYDROLASE
2gve:A (PRO97) to (THR133) TIME-OF-FLIGHT NEUTRON DIFFRACTION STRUCTURE OF D-XYLOSE ISOMERASE | TIM BARREL-BETA-ALPHA-BARRELS, TWO METAL BINDING SITES, PROTONATION STATES OF RESIDUES, ISOMERASE
3ilv:A (CYS52) to (LEU85) CRYSTAL STRUCTURE OF A GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE FROM CYTOPHAGA HUTCHINSONII | NAD(+) SYNTHETASE, CYTOPHAGA HUTCHINSONII, PROTEIN STRUCTURE INITIATIVE II(PSI II), NYSGXRC, 11244E, STRUCTURAL GENOMICS, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, ATP-BINDING, LIGASE, NAD, NUCLEOTIDE-BINDING
2gyi:A (PRO96) to (GLY137) DESIGN, SYNTHESIS, AND CHARACTERIZATION OF A POTENT XYLOSE ISOMERASE INHIBITOR, D-THREONOHYDROXAMIC ACID, AND HIGH-RESOLUTION X-RAY CRYSTALLOGRAPHIC STRUCTURE OF THE ENZYME-INHIBITOR COMPLEX | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
4zvz:D (THR187) to (THR230) CO-CRYSTAL STRUCTURES OF PP5 IN COMPLEX WITH 5-METHYL-7- OXABICYCLO[2.2.1]HEPTANE-2,3-DICARBOXYLIC ACID | PROTEIN PHOSPHATASE 5, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3iru:A (ASP220) to (ASP253) CRYSTAL STRUCTURE OF PHOSHONOACETALDEHYDE HYDROLASE LIKE PROTEIN FROM OLEISPIRA ANTARCTICA | OLEISPIRA ANTARCTICA, PHOSPHONOACETALDEHYDE HYDROLASE LIKE PROTEIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
3iru:B (ASP220) to (ASP253) CRYSTAL STRUCTURE OF PHOSHONOACETALDEHYDE HYDROLASE LIKE PROTEIN FROM OLEISPIRA ANTARCTICA | OLEISPIRA ANTARCTICA, PHOSPHONOACETALDEHYDE HYDROLASE LIKE PROTEIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
4ljy:A (SER222) to (GLY247) CRYSTAL STRUCTURE OF RNA SPLICING EFFECTOR PRP5 IN COMPLEX WITH ADP | PRP5, DEAD BOX, RNA SPLICING, HYDROLASE
2hai:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE IN COMPLEX WITH NOVEL CLASS OF DIHYDROPYRONE-CONTAINING INHIBITOR. | HCV RNA POLYMERASE, TRANSFERASE
2wcx:A (GLY188) to (THR221) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN COMPLEX WITH THIENOPYRROLE-BASED FINGER-LOOP INHIBITORS | ENVELOPE PROTEIN, HEPATITIS C VIRUS, RNA-DEPENDENT RNA-POLYMERASE, NUCLEOTIDE-BINDING, ALLOSTERIC INHIBITOR, NON NUCLEOSIDE INHIBITOR, NNI, HCV, NS5B, MEMBRANE, HELICASE, HYDROLASE, POLYMERASE, ATP-BINDING, RNA-BINDING, GENOTYPE 1B, VIRAL PROTEIN, TRANSMEMBRANE, RNA REPLICATION
2weq:A (LYS178) to (THR210) YEAST HSP90 N-TERMINAL DOMAIN LI-IV MUTANT WITH GELDANAMYCIN | ATPASE, CYTOPLASM, CHAPERONE, ATP-BINDING, PHOSPHOPROTEIN, STRESS RESPONSE, NUCLEOTIDE-BINDING
3vqs:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vqs:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vqs:C (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vqs:D (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1tuy:B (PHE284) to (THR329) ACETATE KINASE COMPLEXED WITH ADP, ALF3 AND ACETATE | ALPHA/BETA, ASKHA (ACETATE AND SUGAR KINASES, HSC70, ACTIN) SUPERFAMILY, ALF3 AND ACETATE, TRANSFERASE
2wi1:A (LYS191) to (GLU223) ORALLY ACTIVE 2-AMINO THIENOPYRIMIDINE INHIBITORS OF THE HSP90 CHAPERONE | PU3, HSP90, ATPASE, CHAPERONE, HEAT SHOCK, STRESS RESPONSE, NUCLEOTIDE-BINDING, ATP-BINDING, PHOSPHOPROTEIN, PHOSPHORYLATION
2wi7:A (LYS191) to (GLU223) ORALLY ACTIVE 2-AMINO THIENOPYRIMIDINE INHIBITORS OF THE HSP90 CHAPERONE | PU3, HSP90, ATPASE, CHAPERONE, HEAT SHOCK, STRESS RESPONSE, NUCLEOTIDE-BINDING, ATP-BINDING, PHOSPHOPROTEIN, PHOSPHORYLATION
2hk1:C (ASN73) to (GLY106) CRYSTAL STRUCTURE OF D-PSICOSE 3-EPIMERASE (DPEASE) IN THE PRESENCE OF D-FRUCTOSE | TIM-BARREL, ISOMERASE
1htt:A (SER170) to (ASN274) HISTIDYL-TRNA SYNTHETASE | COMPLEX (TRNA SYNTHETASE/HIS-ADENYLATE), AMINOACYL-TRNA SYNTHASE, LIGASE, SYNTHETASE
2hkx:B (ASN11) to (SER34) STRUCTURE OF COOA MUTANT (N127L/S128L) FROM CARBOXYDOTHERMUS HYDROGENOFORMANS | COOA, TRANSCRIPTION FACTOR, HEME PROTEIN, TRANSCRIPTION REGULATOR
5a1f:A (SER628) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PLU1 IN COMPLEX WITH N-OXALYLGLYCINE. | OXIDOREDUCTASE, LYSINE-SPECIFIC DEMETHYLASE 5B
1u1i:D (ASP1459) to (ILE1496) MYO-INOSITOL PHOSPHATE SYNTHASE MIPS FROM A. FULGIDUS | NAD COFACTOR, METAL IONS, ISOMERASE
2wom:B (ARG358) to (LYS390) CRYSTAL STRUCTURE OF UK-453061 BOUND TO HIV-1 REVERSE TRANSCRIPTASE (K103N). | AIDS, NON-NUCLEOSIDE INHIBITOR, DRUG DESIGN, TRANSFERASE, NNRTI, SBDD
2won:B (ARG358) to (LYS390) CRYSTAL STRUCTURE OF UK-453061 BOUND TO HIV-1 REVERSE TRANSCRIPTASE (WILD-TYPE). | AIDS, NON-NUCLEOSIDE INHIBITOR, DRUG DESIGN, TRANSFERASE, NNRTI, SBDD
3w1i:A (PRO340) to (LYS377) CRYSTAL STRUCTURE OF THE N-TERMINAL TRUNCATED SELENOCYSTEINE SYNTHASE SELA | HOMODECAMER, PENTAMER OF DIMERS, FOLD-TYPE I PYRIDOXAL 5'-PHOSPHATE (PLP) DEPENDENT ENZYME, L-SERYL-TRNA(SEC) SELENIUM TRANSFERASE, SELENOCYSTEINE SYNTHESIS, SELENIUM METABOLISM, TRANSFERASE
5a3n:A (SER628) to (ARG679) CRYSTAL STRUCTURE OF HUMAN PLU-1 (JARID1B) IN COMPLEX WITH KDOAM25A | OXIDOREDUCTASE
5a3p:A (SER628) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN PLU1 (JARID1B). | OXIDOREDUCTASE
4lwe:A (LYS191) to (LYS224) CRYSTAL STRUCTURE OF THE HUMAN HSP90-ALPHA N-DOMAIN BOUND TO THE HSP90 INHIBITOR FJ2 | ROSSMANN FOLD, ATP BINDING, MOLECULARCHAPERONE, CHAPERONE
2hwh:A (GLY188) to (ARG222) HCV NS5B ALLOSTERIC INHIBITOR COMPLEX | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE
2hwh:B (GLY188) to (ARG222) HCV NS5B ALLOSTERIC INHIBITOR COMPLEX | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE
2hwi:A (GLY188) to (ARG222) HCV NS5B ALLOSTERIC INHIBITOR COMPLEX | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE
2hwi:B (GLY188) to (ARG222) HCV NS5B ALLOSTERIC INHIBITOR COMPLEX | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE
1ias:A (THR176) to (GLU209) CYTOPLASMIC DOMAIN OF UNPHOSPHORYLATED TYPE I TGF-BETA RECEPTOR CRYSTALLIZED WITHOUT FKBP12 | KINASE, TGF-BETA RECEPTOR, GS REGION, TRANSFERASE
1ias:B (THR176) to (GLU209) CYTOPLASMIC DOMAIN OF UNPHOSPHORYLATED TYPE I TGF-BETA RECEPTOR CRYSTALLIZED WITHOUT FKBP12 | KINASE, TGF-BETA RECEPTOR, GS REGION, TRANSFERASE
1ias:C (THR176) to (GLU209) CYTOPLASMIC DOMAIN OF UNPHOSPHORYLATED TYPE I TGF-BETA RECEPTOR CRYSTALLIZED WITHOUT FKBP12 | KINASE, TGF-BETA RECEPTOR, GS REGION, TRANSFERASE
1ias:D (THR176) to (GLU209) CYTOPLASMIC DOMAIN OF UNPHOSPHORYLATED TYPE I TGF-BETA RECEPTOR CRYSTALLIZED WITHOUT FKBP12 | KINASE, TGF-BETA RECEPTOR, GS REGION, TRANSFERASE
1ias:E (THR176) to (GLU209) CYTOPLASMIC DOMAIN OF UNPHOSPHORYLATED TYPE I TGF-BETA RECEPTOR CRYSTALLIZED WITHOUT FKBP12 | KINASE, TGF-BETA RECEPTOR, GS REGION, TRANSFERASE
4m0r:B (ARG187) to (ALA222) TRIANTHRANILATE-LIKE ANALOGUE BOUND TO ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE (ANPRT; TRPD). | MAGNESIUM BINDING, PHOSPHORIBOSYLPYROPHOSPHATE, PRPP, INHIBITOR COMPLEX, TRI-ANTHRANILATE ANALOGUE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, PHOSPHORIBOSYLTRANSFERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2i1r:A (GLY188) to (ARG222) NOVEL THIAZOLONES AS HCV NS5B POLYMERASE INHIBITORS: FURTHER DESIGNS, SYNTHESIS, SAR AND X-RAY COMPLEX STRUCTURE | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE
2i1r:B (GLY188) to (ARG222) NOVEL THIAZOLONES AS HCV NS5B POLYMERASE INHIBITORS: FURTHER DESIGNS, SYNTHESIS, SAR AND X-RAY COMPLEX STRUCTURE | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE
1uf9:A (ASP67) to (LEU115) CRYSTAL STRUCTURE OF TT1252 FROM THERMUS THERMOPHILUS | P-LOOP, NUCLEOTIDE BINDING DOMAIN, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, UNKNOWN FUNCTION
1uf9:B (ASP67) to (LEU115) CRYSTAL STRUCTURE OF TT1252 FROM THERMUS THERMOPHILUS | P-LOOP, NUCLEOTIDE BINDING DOMAIN, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, UNKNOWN FUNCTION
1uf9:C (ASP67) to (LEU115) CRYSTAL STRUCTURE OF TT1252 FROM THERMUS THERMOPHILUS | P-LOOP, NUCLEOTIDE BINDING DOMAIN, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, UNKNOWN FUNCTION
1uio:A (TYR68) to (SER103) ADENOSINE DEAMINASE (HIS 238 ALA MUTANT) | HYDROLASE, NUCLEOTIDE METABOLISM, ZINC COFACTOR TIM BARREL
4m3u:A (ASP524) to (LEU580) RB69 DNA POLYMERASE TERNARY COMPLEX WITH DT/DG AT POSITION N-3 OF PRIMER/TEMPLATE DUPLEX | RB69 POL, QUADRUPLE, DT/DG, N-3, RB69, HYDROLASE-DNA COMPLEX
2iae:C (PHE6) to (ARG49) CRYSTAL STRUCTURE OF A PROTEIN PHOSPHATASE 2A (PP2A) HOLOENZYME. | PROTEIN PHOSPHORYLATION, PHOSPHATASE, PP2A, B56, TUMOR SUPPRESSOR, METHYLATION, HYDROLASE, TOXIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2iae:F (PHE6) to (ARG49) CRYSTAL STRUCTURE OF A PROTEIN PHOSPHATASE 2A (PP2A) HOLOENZYME. | PROTEIN PHOSPHORYLATION, PHOSPHATASE, PP2A, B56, TUMOR SUPPRESSOR, METHYLATION, HYDROLASE, TOXIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2ie4:C (PHE6) to (CYS50) STRUCTURE OF THE PROTEIN PHOSPHATASE 2A CORE ENZYME BOUND TO OKADAIC ACID | PROTEIN-PROTEIN COMPLEX, HEAT REPEAT, SIGNALING PROTEIN, HYDROLASE
2ied:B (THR196) to (LYS233) CRYSTAL STRUCTURE OF ISONIAZID-RESISTANT S94A ENOYL-ACP(COA) REDUCTASE MUTANT ENZYME FROM MYCOBACTERIUM TUBERCULOSIS UNCOMPLEXED | ENOYL-ACYL CARRIER PROTEIN, INHA REDUCTASE, OXIDOREDUCTASE
2ied:C (ALA198) to (LYS233) CRYSTAL STRUCTURE OF ISONIAZID-RESISTANT S94A ENOYL-ACP(COA) REDUCTASE MUTANT ENZYME FROM MYCOBACTERIUM TUBERCULOSIS UNCOMPLEXED | ENOYL-ACYL CARRIER PROTEIN, INHA REDUCTASE, OXIDOREDUCTASE
2ied:D (THR196) to (LYS233) CRYSTAL STRUCTURE OF ISONIAZID-RESISTANT S94A ENOYL-ACP(COA) REDUCTASE MUTANT ENZYME FROM MYCOBACTERIUM TUBERCULOSIS UNCOMPLEXED | ENOYL-ACYL CARRIER PROTEIN, INHA REDUCTASE, OXIDOREDUCTASE
2if2:A (ASP65) to (ALA112) CRYSTAL STRUCTURE OF THE PUTATIVE DEPHOSPHO-COA KINASE FROM AQUIFEX AEOLICUS, NORTHEAST STRUCTURAL GENOMICS TARGET QR72. | ALPHA-BETA PROTEIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, TRANSFERASE
2if2:B (ASP65) to (ALA112) CRYSTAL STRUCTURE OF THE PUTATIVE DEPHOSPHO-COA KINASE FROM AQUIFEX AEOLICUS, NORTHEAST STRUCTURAL GENOMICS TARGET QR72. | ALPHA-BETA PROTEIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, TRANSFERASE
5abo:A (ASP237) to (ASP280) CRYSTAL STRUCTURE ANALYSIS OF FUNGAL VERSATILE PEROXIDASE FROM PLEUROTUS ERYNGII. MUTANT VPI-BR. MUTATED RESIDUES T2K, D69S, T70D, S86E, A131K, D146T, Q202L, Q219K, H232E, Q239R, L288R, S301K, A308R, A309K AND A314R. | CLASS II (FUNGAL) PEROXIDASES, PROTOPORPHYRIN IX, ELECTRON TRANSFER, LIGNIN PEROXIDASE, LIGNIN DEGRADATION, MANGANESE PEROXIDASE, MN-INDEPENDENT OXIDATION PHENOLIC NON-PHENOLIC AROMATICS, MNII OXIDATION, PEROXIDASE, POLYVALENT PEROXIDASE, OXIDOREDUCTASE, HEME, HYDROGEN PEROXIDE, IRON, MANGANESE, METAL-BINDING, SECRETED, ZYMOGEN
3wco:B (PRO340) to (LYS377) CRYSTAL STRUCTURE OF THE DEPENTAMERIZED MUTANT OF N-TERMINAL TRUNCATED SELENOCYSTEINE SYNTHASE SELA | FOLD-TYPE-I PYRIDOXAL 5'-PHOSPHATE (PLP) DEPENDENT ENZYME, HOMODIMER, L-SERYL-TRNA(SEC) SELENIUM TRANSFERASE, SELENOCYSTEINE SYNTHESIS, SELENIUM METABOLISM, TRANSFERASE
5ac4:B (VAL178) to (GLY220) GH20C, BETA-HEXOSAMINIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH GALNAC | HYDROLASE, BACTERIAL PROTEINS, CARBOHYDRATE CONFORMATION, CATALYTIC DOMAIN, HOST-PATHOGEN INTERACTIONS, HYDROLYSIS, POLYSACCHARIDES, VIRULENCE FACTORS
2ijn:A (GLY188) to (ARG222) ISOTHIAZOLES AS ACTIVE-SITE INHIBITORS OF HCV NS5B POLYMERASE | HCV; NS5B; VIRAL RNA DIRECTED RNA POLYMERASE; RDRP; ACTIVE SITE; COVALENT INHIBITOR, TRANSCRIPTION,TRANSFERASE
2ijn:B (GLY188) to (ARG222) ISOTHIAZOLES AS ACTIVE-SITE INHIBITORS OF HCV NS5B POLYMERASE | HCV; NS5B; VIRAL RNA DIRECTED RNA POLYMERASE; RDRP; ACTIVE SITE; COVALENT INHIBITOR, TRANSCRIPTION,TRANSFERASE
5aeu:D (GLY20) to (MET58) CRYSTAL STRUCTURE OF II9 VARIANT OF BIPHENYL DIOXYGENASE FROM BURKHOLDERIA XENOVORANS LB400 | OXIDOREDUCTASE, BPHAE-II9, BIPHENYL, POLYCHLORINATED BIPHENYLS
5aew:L (GLY20) to (MET58) CRYSTAL STRUCTURE OF II9 VARIANT OF BIPHENYL DIOXYGENASE FROM BURKHOLDERIA XENOVORANS LB400 IN COMPLEX WITH BIPHENYL | OXIDOREDUCTASE, BIPHENYL DIOXYGENASE, BPHAE-II9, BIPHENYL, POLYCHLORINATED BIPHENYLS
5aew:T (GLY20) to (MET58) CRYSTAL STRUCTURE OF II9 VARIANT OF BIPHENYL DIOXYGENASE FROM BURKHOLDERIA XENOVORANS LB400 IN COMPLEX WITH BIPHENYL | OXIDOREDUCTASE, BIPHENYL DIOXYGENASE, BPHAE-II9, BIPHENYL, POLYCHLORINATED BIPHENYLS
1uy6:A (LYS191) to (GLU223) HUMAN HSP90-ALPHA WITH 9-BUTYL-8-(3,4,5-TRIMETHOXY-BENZYL)-9H-PURIN-6-YLAMINE | HSP90, ATPASE, PU3, CHAPERONE, ATP-BINDING, HEAT SHOCK
2iof:A (THR214) to (GLU247) CRYSTAL STRUCTURE OF PHOSPHONOACETALDEHYDE HYDROLASE WITH SODIUM BOROHYDRIDE-REDUCED SUBSTRATE INTERMEDIATE | PHOSPHONOACETALDEHYDE HYDROLASE, HALOACID DEHALOGENASE SUPERFAMILY
1j0y:B (ASP236) to (VAL291) BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES IN COMPLEX WITH GLUCOSE | HYDROLASE, BETA-AMYLASE, RAW-STARCH BINDING DOMAIN
1j0z:A (ASP236) to (ALA289) BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES IN COMPLEX WITH MALTOSE | HYDROLASE, BETA-AMYLASE, RAW-STARCH BINDING DOMAIN
1j11:A (ASP236) to (TRP293) BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES IN COMPLEX WITH ALPHA-EPG | HYDROLASE, BETA-AMYLASE, RAW-STARCH BINDING DOMAIN
1j12:D (ASP236) to (ALA289) BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES IN COMPLEX WITH ALPHA-EBG | HYDROLASE, BETA-AMYLASE, RAW-STARCH BINDING DOMAIN
4mh8:A (ASP400) to (ALA436) THE CRYSTAL STRUCTURE OF THE MONOMERIC REVERSE TRANSCRIPTASE FROM MOLONEY MURINE LEUKEMIA VIRUS | RNA AND DNA DEPENDENT DNA POLYMERASE, REVERSE TRANSCRIPTASE, TRANSFERASE, REPLICATION, HYDROLASE
4mia:A (GLY188) to (THR221) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH RG7109 (N-{4-[6-TERT-BUTYL-5-METHOXY-8-(6-METHOXY-2-OXO-2,5- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PHENYL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mia:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH RG7109 (N-{4-[6-TERT-BUTYL-5-METHOXY-8-(6-METHOXY-2-OXO-2,5- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PHENYL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mib:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH COMPOUND 48 (N-({(3S)-1-[6-TERT-BUTYL-5-METHOXY-8-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PYRROLIDIN-3-YL}METHYL) METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mib:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH COMPOUND 48 (N-({(3S)-1-[6-TERT-BUTYL-5-METHOXY-8-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PYRROLIDIN-3-YL}METHYL) METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk7:A (GLY188) to (CYS223) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 2 (3-(3-TERT-BUTYL-4-METHOXYPHENYL)PYRIDIN-2(1H)-ONE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk7:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 2 (3-(3-TERT-BUTYL-4-METHOXYPHENYL)PYRIDIN-2(1H)-ONE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk8:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 4 (N-(4-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]ETHYL}PHENYL)METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk8:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 4 (N-(4-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]ETHYL}PHENYL)METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk9:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 12 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk9:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 12 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mka:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 13 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mka:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 13 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1v6x:A (PRO90) to (VAL126) CRYSTAL STRUCTURE OF XYLANASE FROM STREPTOMYCES OLIVACEOVIRIDIS E-86 COMPLEXED WITH 3(3)-4-O-METHYL-ALPHA- D-GLUCURONOSYL-XYLOTRIOSE | ALPHA-BETA BARREL, PROTEIN-SUGAR COMPLEX, CARBOHYDRATE BINDING MODULE, HYDROLASE
4mkb:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 14 (N-(4-{(E)-2-[3-TERT-BUTYL-2-METHOXY-5-(3-OXO-2,3- DIHYDROPYRIDAZIN-4-YL)PHENYL]ETHENYL}PHENYL)METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mkb:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 14 (N-(4-{(E)-2-[3-TERT-BUTYL-2-METHOXY-5-(3-OXO-2,3- DIHYDROPYRIDAZIN-4-YL)PHENYL]ETHENYL}PHENYL)METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2ivo:D (GLY252) to (PRO278) STRUCTURE OF UP1 PROTEIN | UP1 KEOPS COMPLEX, FE/ZN DEPENDENT NUCLEOTIDE PHOSPHATASE, METALLOPROTEASE, HYPOTHETICAL PROTEIN, HYDROLASE, ZINC, PROTEASE, METAL-BINDING
3wnm:A (TYR383) to (ASN414) D308A MUTANT OF BACILLUS CIRCULANS T-3040 CYCLOISOMALTOOLIGOSACCHARIDE GLUCANOTRANSFERASE COMPLEXED WITH ISOMALTOHEPTAOSE | C2 TYPE IMMUNOGLOBULIN FOLD, (BETA/ALPHA)8-BARREL, BETA-JELLY ROLL, GREEK KEY, GLYCOSIDE HYDROLASE, ALPHA-1,6-GLUCAN, TRANSFERASE
3wno:A (TYR383) to (ASN414) D308A MUTANT OF BACILLUS CIRCULANS T-3040 CYCLOISOMALTOOLIGOSACCHARIDE GLUCANOTRANSFERASE COMPLEXED WITH CYCLOISOMALTOOCTAOSE | C2 TYPE IMMUNOGLOBULIN FOLD, (BETA/ALPHA)8-BARREL, BETA-JELLY ROLL, GREEK KEY, GLYCOSIDE HYDROLASE, ALPHA-1,6-GLUCAN, TRANSFERASE
3wnp:B (TYR383) to (ASN414) D308A, F268V, D469Y, A513V, AND Y515S QUINTUPLE MUTANT OF BACILLUS CIRCULANS T-3040 CYCLOISOMALTOOLIGOSACCHARIDE GLUCANOTRANSFERASE COMPLEXED WITH ISOMALTOUNDECAOSE | C2 TYPE IMMUNOGLOBULIN FOLD, (BETA/ALPHA)8-BARREL, BETA-JELLY ROLL, GREEK KEY, GLYCOSIDE HYDROLASE, ALPHA-1,6-GLUCAN, TRANSFERASE
2ix3:A (GLN774) to (GLY798) STRUCTURE OF YEAST ELONGATION FACTOR 3 | PROTEIN BIOSYNTHESIS, TRANSLATION, ELONGATION FACTOR, PHOSPHORYLATION, NUCLEOTIDE-BINDING, RRNA-BINDING, RNA- BINDING, ACETYLATION, ATP-BINDING
4mo4:A (PRO38) to (HIS94) CRYSTAL STRUCTURE OF ANMK BOUND TO AMPPCP | ATPASE DOMAIN, KINASE, ATP-BINDING, TRANSFERASE
4mo4:B (ALA39) to (HIS94) CRYSTAL STRUCTURE OF ANMK BOUND TO AMPPCP | ATPASE DOMAIN, KINASE, ATP-BINDING, TRANSFERASE
4mo4:C (ALA39) to (HIS94) CRYSTAL STRUCTURE OF ANMK BOUND TO AMPPCP | ATPASE DOMAIN, KINASE, ATP-BINDING, TRANSFERASE
4mo4:D (ALA39) to (HIS94) CRYSTAL STRUCTURE OF ANMK BOUND TO AMPPCP | ATPASE DOMAIN, KINASE, ATP-BINDING, TRANSFERASE
4mo5:A (ALA39) to (HIS94) CRYSTAL STRUCTURE OF ANMK BOUND TO AMPPCP AND ANHMURNAC | ATPASE DOMAIN, KINASE, ATP BINDING, TRANSFERASE
4mo5:B (PRO38) to (HIS94) CRYSTAL STRUCTURE OF ANMK BOUND TO AMPPCP AND ANHMURNAC | ATPASE DOMAIN, KINASE, ATP BINDING, TRANSFERASE
4mo5:C (PRO38) to (HIS94) CRYSTAL STRUCTURE OF ANMK BOUND TO AMPPCP AND ANHMURNAC | ATPASE DOMAIN, KINASE, ATP BINDING, TRANSFERASE
4mo5:D (ALA39) to (HIS94) CRYSTAL STRUCTURE OF ANMK BOUND TO AMPPCP AND ANHMURNAC | ATPASE DOMAIN, KINASE, ATP BINDING, TRANSFERASE
2xd6:A (LYS178) to (THR210) HSP90 COMPLEXED WITH A RESORCYLIC ACID MACROLACTONE. | CHAPERONE, INHIBITOR, ATPASE
1vem:A (ASP236) to (TRP293) CRYSTAL STRUCTURE ANALYSIS OF BACILLUS CEREUS BETA-AMYLASE AT THE OPTIMUM PH (6.5) | BETA-ALPHA-BARRELS, OPTIMUM PH, HYDROLASE
2xdk:A (LYS191) to (LYS224) STRUCTURE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND | CHAPERONE
2xdq:B (ASP61) to (THR94) DARK OPERATIVE PROTOCHLOROPHYLLIDE OXIDOREDUCTASE (CHLN- CHLB)2 COMPLEX | OXIDOREDUCTASE, DPOR, (BACTERIO)CHLOROPHYLL BIOSYNTHESIS, PHOTOSYNTHESIS, NITROGENASE-LIKE
3wqk:A (SER5) to (PRO32) CRYSTAL STRUCTURE OF RV3378C WITH PO4 | PHOSPHATASE, DITERPENE SYNTHASE, HYDROLASE
3wqm:A (SER5) to (ASP34) CRYSTAL STRUCTURE OF RV3378C WITH INHIBITOR BPH-629 | DITERPENE SYNTHASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3wqn:A (SER5) to (PHE33) CRYSTAL STRUCTURE OF RV3378C_Y51F WITH TPP | DITERPENE SYNTHASE, HYDROLASE
2xdx:A (LYS191) to (GLU223) STRUCTRE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND | CHAPERONE, INHIBITOR, STRESS RESPONSE
3wqq:B (LYS300) to (LYS336) CRYSTAL STRUCTURE OF PFDXR COMPLEXED WITH INHIBITOR-3 | REDUCTOISOMERASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
1jjv:A (ARG67) to (VAL111) DEPHOSPHO-COA KINASE IN COMPLEX WITH ATP | P-LOOP NUCLEOTIDE-BINDING FOLD, STRUCTURE 2 FUNCTION PROJECT, S2F, STRUCTURAL GENOMICS, TRANSFERASE
1jkg:B (THR380) to (PRO421) STRUCTURAL BASIS FOR THE RECOGNITION OF A NUCLEOPORIN FG- REPEAT BY THE NTF2-LIKE DOMAIN OF TAP-P15 MRNA NUCLEAR EXPORT FACTOR | NTF2-LIKE DOMAIN, TRANSPORT PROTEIN
1jkh:B (ARG358) to (LYS390) CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DMP-266(EFAVIRENZ) | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NON-NUCLEOSIDE INHIBITOR, DMP-266, EFAVIRENZ, DRUG RESISTANCE MUTATIONS, DRUG DESIGN, TRANSFERASE
1vhl:A (ARG67) to (PRO113) CRYSTAL STRUCTURE OF DEPHOSPHO-COA KINASE WITH ADENOSINE-5'- DIPHOSPHATE | STRUCTURAL GENOMICS, TRANSFERASE
1vhl:B (ARG67) to (VAL111) CRYSTAL STRUCTURE OF DEPHOSPHO-COA KINASE WITH ADENOSINE-5'- DIPHOSPHATE | STRUCTURAL GENOMICS, TRANSFERASE
1vht:B (ARG67) to (VAL111) CRYSTAL STRUCTURE OF DEPHOSPHO-COA KINASE WITH BIS(ADENOSINE)-5'-TRIPHOSPHATE | STRUCTURAL GENOMICS, TRANSFERASE
3wry:B (THR271) to (VAL303) CRYSTAL STRUCTURE OF HELICASE COMPLEX 2 | ALPHA/BETA DOMAIN, HELICASE, TRANSFERASE
2xhu:A (GLY188) to (ARG222) HCV-J4 NS5B POLYMERASE ORTHORHOMBIC CRYSTAL FORM | REPLICATION, TRANSCRIPTION, TRANSFERASE
2xhu:B (GLY188) to (ARG222) HCV-J4 NS5B POLYMERASE ORTHORHOMBIC CRYSTAL FORM | REPLICATION, TRANSCRIPTION, TRANSFERASE
2xi2:B (GLY188) to (ARG222) HCV-H77 NS5B APO POLYMERASE | TRANSFERASE, NONSTRUCTURAL PROTEIN, REPLICATION, RDRP, DE NOVO PRIMING
1jqg:A (PRO113) to (PHE198) CRYSTAL STRUCTURE OF THE CARBOXYPEPTIDASE A FROM HELICOVERPA ARMIGERA | PRO-PROTEIN, HYDROLASE
2xj9:A (ASN77) to (PRO112) DIMER STRUCTURE OF THE BACTERIAL CELL DIVISION REGULATOR MIPZ | REPLICATION, CELL DIVISION, ATPASE, WACA
2xj9:B (ASN77) to (ASP110) DIMER STRUCTURE OF THE BACTERIAL CELL DIVISION REGULATOR MIPZ | REPLICATION, CELL DIVISION, ATPASE, WACA
2xk2:A (LYS191) to (LYS224) STRUCTURE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND | CHAPERONE, STRESS RESPONSE
2jc0:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB655264 | HEPATITIS, POLYMERASE, HYDROLASE
2jc0:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB655264 | HEPATITIS, POLYMERASE, HYDROLASE
2jc1:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB698223 | HEPATITIS, POLYMERASE, HYDROLASE
2jc1:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB698223 | HEPATITIS, POLYMERASE, HYDROLASE
2jcv:A (LYS128) to (ASP151) X-RAY STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, DXR, RV2870C, FROM MYCOBACTERIUM TUBERCULOSIS, IN COMPLEX WITH FOSMIDOMYCIN AND NADPH | OXIDOREDUCTASE, DOXP/MEP PATHWAY, ISOPRENE BIOSYNTHESIS, 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, NADP, RV2870C, METAL-BINDING
2xr8:H (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE FROM BURKHOLDERIA XENOVORANS LB400 | OXIDOREDUCTASE, DEGRADATION, BPDO
2xr8:V (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE FROM BURKHOLDERIA XENOVORANS LB400 | OXIDOREDUCTASE, DEGRADATION, BPDO
2xr8:X (GLY20) to (PRO59) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE FROM BURKHOLDERIA XENOVORANS LB400 | OXIDOREDUCTASE, DEGRADATION, BPDO
2jcx:A (LYS128) to (ASN151) X-RAY STRUCTURE OF MUTANT 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, DXR, RV2870C, FROM MYCOBACTERIUM TUBERCULOSIS, IN COMPLEX WITH FOSMIDOMYCIN AND NADPH | OXIDOREDUCTASE, DOXP/MEP PATHWAY, ISOPRENE BIOSYNTHESIS, 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, NADP, RV2870C, METAL-BINDING
3j9u:K (THR9) to (LYS140) YEAST V-ATPASE STATE 2 | V-ATPASE, V-TYPE ATPASE, VACUOLAR-TYPE ATPASE, PROTON PUMP, HYDROLASE
3j9v:G (THR9) to (LYS140) YEAST V-ATPASE STATE 3 | V-ATPASE, V-TYPE ATPASE, VACUOLAR-TYPE ATPASE, PROTON PUMP, HYDROLASE
2xrx:J (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE IN COMPLEX WITH BIPHENYL FROM BURKHOLDERIA XENOVORANS LB400 | OXIDOREDUCTASE, DEGRADATION, BPDO
2xrx:P (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE IN COMPLEX WITH BIPHENYL FROM BURKHOLDERIA XENOVORANS LB400 | OXIDOREDUCTASE, DEGRADATION, BPDO
2xrx:T (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE IN COMPLEX WITH BIPHENYL FROM BURKHOLDERIA XENOVORANS LB400 | OXIDOREDUCTASE, DEGRADATION, BPDO
2xrx:X (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE IN COMPLEX WITH BIPHENYL FROM BURKHOLDERIA XENOVORANS LB400 | OXIDOREDUCTASE, DEGRADATION, BPDO
1w46:A (ASP6) to (GLY50) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH ADP AND MG | DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w46:B (ASP6) to (GLY50) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH ADP AND MG | DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w46:C (ASP6) to (GLY50) P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH ADP AND MG | DSRNA VIRUS, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w4b:A (ASP6) to (GLY50) P4 PROTEIN FROM PHI12 IN COMPLEX WITH PRODUCT (AMPCPP MG 22C) | VIRUS DSRNA, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
1w4b:B (ASP6) to (GLY50) P4 PROTEIN FROM PHI12 IN COMPLEX WITH PRODUCT (AMPCPP MG 22C) | VIRUS DSRNA, PACKAGING ATPASE, HEXAMERIC HELICASE, MOLECULAR MOTOR, NON-HYDROLYSABLE ATP ANALOGUE, HYDROLASE
3ja8:4 (LYS252) to (ASN307) CRYO-EM STRUCTURE OF THE MCM2-7 DOUBLE HEXAMER | CRYO-EM, SINGLE PARTICLE, MCM2-7, DNA REPLICATION, HYDROLASE
2xso:J (GLY20) to (MET58) CRYSTAL STRUCTURE OF P4 VARIANT OF BIPHENYL DIOXYGENASE FROM BURKHOLDERIA XENOVORANS LB400 | OXIDOREDUCTASE
5bca:A (ASP236) to (ALA289) BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES | HYDROLASE, BETA-AMYLASE, RAW-STARCH BINDING DOMAIN
5bp2:A (PRO929) to (HIS971) DEHYDRATASE DOMAIN (DH) OF THE MYCOCEROSIC ACID SYNTHASE (MAS), CRYSTAL FORM 1 | LYASE, PKS, DEHYDRATASE, DH, POLYKETIDE
5bp2:C (HIS928) to (ASP972) DEHYDRATASE DOMAIN (DH) OF THE MYCOCEROSIC ACID SYNTHASE (MAS), CRYSTAL FORM 1 | LYASE, PKS, DEHYDRATASE, DH, POLYKETIDE
5bp2:D (PRO929) to (HIS971) DEHYDRATASE DOMAIN (DH) OF THE MYCOCEROSIC ACID SYNTHASE (MAS), CRYSTAL FORM 1 | LYASE, PKS, DEHYDRATASE, DH, POLYKETIDE
5bq2:A (PRO85) to (VAL111) CRYSTAL STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE (UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE, EPT) FROM PSEUDOMONAS AERUGINOSA | SSGCID, UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE, UDP-N- ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE, ENOYLPYRUVATE TRANSFERASE, EPT, MURA, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
5bq2:C (PRO85) to (VAL111) CRYSTAL STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE (UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE, EPT) FROM PSEUDOMONAS AERUGINOSA | SSGCID, UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE, UDP-N- ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE, ENOYLPYRUVATE TRANSFERASE, EPT, MURA, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
5bq2:D (PRO85) to (VAL111) CRYSTAL STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE (UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE, EPT) FROM PSEUDOMONAS AERUGINOSA | SSGCID, UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE, UDP-N- ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE, ENOYLPYRUVATE TRANSFERASE, EPT, MURA, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
1w8s:I (ASN37) to (GLN61) THE MECHANISM OF THE SCHIFF BASE FORMING FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE: STRUCTURAL ANALYSIS OF REACTION INTERMEDIATES | ALDOLASE, FRUCTOSE 1, 6-BISPHOSPHATE, TIM BARREL, GLYCOLYTIC, ARCHAEAL, CATALYTIC MECHANISM, REACTION INTERMEDIATE, LYASE
4n9x:A (SER230) to (SER264) CRYSTAL STRUCTURE OF THE OCTAPRENYL-METHYL-METHOXY-BENZQ MOLECULE FROM ERWINA CAROTOVORA SUBSP. ATROSEPTICA STRAIN SCRI 1043 / ATCC BAA-672, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET EWR161 | STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET EWR161, OXIDOREDUCTASE
2jis:A (PRO99) to (PHE148) HUMAN CYSTEINE SULFINIC ACID DECARBOXYLASE (CSAD) IN COMPLEX WITH PLP. | PYRIDOXAL PHOSPHATE, ALTERNATIVE SPLICING, PYRIDOXAL PHOSPHATE (PLP), STRUCTURAL GENOMICS CONSORTIUM (SGC), LYASE, VITAMIN B6, DECARBOXYLASE
2jis:B (PRO99) to (PHE148) HUMAN CYSTEINE SULFINIC ACID DECARBOXYLASE (CSAD) IN COMPLEX WITH PLP. | PYRIDOXAL PHOSPHATE, ALTERNATIVE SPLICING, PYRIDOXAL PHOSPHATE (PLP), STRUCTURAL GENOMICS CONSORTIUM (SGC), LYASE, VITAMIN B6, DECARBOXYLASE
5bre:A (SER260) to (GLY306) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI GLUCOKINASE IN COMPLEX WITH INHIBITOR CBZ-GLCN | TRANSFERASE, HEXOSE KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5bre:B (SER260) to (ASP307) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI GLUCOKINASE IN COMPLEX WITH INHIBITOR CBZ-GLCN | TRANSFERASE, HEXOSE KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5brf:B (ALA261) to (ASP307) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI GLUCOKINASE IN COMPLEX WITH INHIBITOR HPOP-GLCN | TRANSFERASE, HEXOSE KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1wao:2 (THR187) to (THR230) PP5 STRUCTURE | HYDROLASE, PHOSPHATASE, PROTEIN-PROTEIN INTERACTIONS, TPR, SUPER-HELIX, X-RAY STRUCTURE
1wao:4 (THR187) to (THR230) PP5 STRUCTURE | HYDROLASE, PHOSPHATASE, PROTEIN-PROTEIN INTERACTIONS, TPR, SUPER-HELIX, X-RAY STRUCTURE
2xx4:A (LYS178) to (THR210) MACROLACTONE INHIBITOR BOUND TO HSP90 N-TERM | CHAPERONE
2xxd:A (GLY188) to (ARG222) HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 1.9 ANGSTROM | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
4ncf:A (PHE546) to (LEU581) CRYSTAL STRUCTURE OF EUKARYOTIC TRANSLATION INITIATION FACTOR EIF5B (399-852) FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH GDP | TRANSLATION INITIATION, GTPASE, EIF5B/IF2, SUBUNIT JOINING, RIBOSOME, TRANSLATION
4ncf:B (PHE546) to (LEU581) CRYSTAL STRUCTURE OF EUKARYOTIC TRANSLATION INITIATION FACTOR EIF5B (399-852) FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH GDP | TRANSLATION INITIATION, GTPASE, EIF5B/IF2, SUBUNIT JOINING, RIBOSOME, TRANSLATION
2jki:A (LYS180) to (THR211) COMPLEX OF HSP90 N-TERMINAL AND SGT1 CS DOMAIN | HSP90 SGT1, STRESS RESPONSE, CHAPERONE
2xym:A (GLY188) to (ARG222) HCV-JFH1 NS5B T385A MUTANT | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
3zhz:A (LYS128) to (ASP151) STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS DXR IN COMPLEX WITH A FOSMIDOMYCIN ANALOGUE | OXIDOREDUCTASE, RV2870C, DOXP/MEP PATHWAY ISPC
3zi0:A (GLU129) to (ASP151) STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS DXR IN COMPLEX WITH A FOSMIDOMYCIN ANALOGUE | OXIDOREDUCTASE, RV2870C, DOXP/MEP PATHWAY, TUBERCULOSIS, ISPC
3zie:E (ILE67) to (GLY99) SEPF-LIKE PROTEIN FROM ARCHAEOGLOBUS FULGIDUS | CELL CYCLE
3zie:F (ILE67) to (GLY99) SEPF-LIKE PROTEIN FROM ARCHAEOGLOBUS FULGIDUS | CELL CYCLE
2y1c:A (GLU129) to (ASP151) X-RAY STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, DXR, RV2870C, FROM MYCOBACTERIUM TUBERCULOSIS, IN COMPLEX WITH MANGANESE. | OXIDOREDUCTASE, DOXP/MEP PATHWAY
2y1c:B (GLU129) to (ASP151) X-RAY STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, DXR, RV2870C, FROM MYCOBACTERIUM TUBERCULOSIS, IN COMPLEX WITH MANGANESE. | OXIDOREDUCTASE, DOXP/MEP PATHWAY
2y1d:A (GLU129) to (ASP151) X-RAY STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, DXR, RV2870C, FROM MYCOBACTERIUM TUBERCULOSIS, IN COMPLEX WITH A 3,4-DICHLOROPHENYL- SUBSTITUTED FOSMIDOMYCIN ANALOGUE AND MANGANESE. | OXIDOREDUCTASE, DOXP/MEP PATHWAY
2y1d:B (GLU129) to (ASP151) X-RAY STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, DXR, RV2870C, FROM MYCOBACTERIUM TUBERCULOSIS, IN COMPLEX WITH A 3,4-DICHLOROPHENYL- SUBSTITUTED FOSMIDOMYCIN ANALOGUE AND MANGANESE. | OXIDOREDUCTASE, DOXP/MEP PATHWAY
2y27:A (CYS377) to (PRO412) CRYSTAL STRUCTURE OF PAAK1 IN COMPLEX WITH ATP FROM BURKHOLDERIA CENOCEPACIA | LIGASE, PHENYLACETIC ACID DEGRADATION PATHWAY
2y27:B (CYS377) to (PRO412) CRYSTAL STRUCTURE OF PAAK1 IN COMPLEX WITH ATP FROM BURKHOLDERIA CENOCEPACIA | LIGASE, PHENYLACETIC ACID DEGRADATION PATHWAY
1kbl:A (GLU45) to (ARG96) PYRUVATE PHOSPHATE DIKINASE | TRANSFERASE, PHOSPHOTRANSFERASE, KINASE
2y4n:A (CYS377) to (PRO412) PAAK1 IN COMPLEX WITH PHENYLACETYL ADENYLATE | LIGASE, PHENYLACETIC ACID DEGRADATION PATHWAY
2y4n:B (CYS377) to (PRO412) PAAK1 IN COMPLEX WITH PHENYLACETYL ADENYLATE | LIGASE, PHENYLACETIC ACID DEGRADATION PATHWAY
3zs9:A (ALA127) to (PHE165) S. CEREVISIAE GET3-ADP-ALF4- COMPLEX WITH A CYTOSOLIC GET2 FRAGMENT | HYDROLASE-TRANSPORT PROTEIN COMPLEX, MEMBRANE PROTEIN, TARGETING FACTOR
2ybu:E (THR235) to (THR266) CRYSTAL STRUCTURE OF HUMAN ACIDIC CHITINASE IN COMPLEX WITH BISDIONIN F | HYDROLASE
2yea:A (LYS191) to (GLU223) HSP90 INHIBITORS AND DRUGS FROM FRAGMENT AND VIRTUAL SCREENING | PU3, ATPASE, CHAPERONE, STRESS RESPONSE, NUCLEOTIDE-BINDING, ATP-BINDING, PHOSPHOPROTEIN, PHOSPHORYLATION
2yeb:A (LYS191) to (GLU223) HSP90 INHIBITORS AND DRUGS FROM FRAGMENT AND VIRTUAL SCREENING | PU3, ATPASE, CHAPERONE, STRESS RESPONSE, NUCLEOTIDE-BINDING, ATP-BINDING, PHOSPHOPROTEIN, PHOSPHORYLATION
2yej:A (LYS191) to (GLU223) HSP90 INHIBITORS AND DRUGS FROM FRAGMENT AND VIRTUAL SCREENING | CHAPERONE, STRESS RESPONSE
2yfi:F (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE VARIANT RR41 (BPDO-RR41) | OXIDOREDUCTASE, DEGRADATION
2yfi:H (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE VARIANT RR41 (BPDO-RR41) | OXIDOREDUCTASE, DEGRADATION
2yfi:J (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE VARIANT RR41 (BPDO-RR41) | OXIDOREDUCTASE, DEGRADATION
2yfj:B (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE VARIANT RR41 WITH DIBENZOFURAN | OXIDOREDUCTASE
2yfj:F (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE VARIANT RR41 WITH DIBENZOFURAN | OXIDOREDUCTASE
2yfj:J (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE VARIANT RR41 WITH DIBENZOFURAN | OXIDOREDUCTASE
2yfj:L (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE VARIANT RR41 WITH DIBENZOFURAN | OXIDOREDUCTASE
2yfl:B (GLY20) to (MET58) CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE VARIANT RR41 WITH 2-CHLORO DIBENZOFURAN | OXIDOREDUCTASE, DEGRADATION, BPDO
3zx0:D (ALA132) to (LYS167) NTPDASE1 IN COMPLEX WITH HEPTAMOLYBDATE | DOMAIN ROTATION, HYDROLASE, POLYOXOMETALLATE, METAL CLUSTER, PURINERGIC SIGNALING
3zx2:A (ALA132) to (LYS167) NTPDASE1 IN COMPLEX WITH DECAVANADATE | DOMAIN ROTATION, HYDROLASE, POLYOXOMETALLATE, METAL CLUSTER, PURINERGIC SIGNALING N
3zx2:D (ALA132) to (LYS167) NTPDASE1 IN COMPLEX WITH DECAVANADATE | DOMAIN ROTATION, HYDROLASE, POLYOXOMETALLATE, METAL CLUSTER, PURINERGIC SIGNALING N
1kvr:A (ALA85) to (SER122) UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL | UDP-GALACTOSE, EPIMERASE, ISOMERASE, GALACTOSE METABOLISM
2yi5:A (LYS191) to (GLU225) STRUCTURAL CHARACTERIZATION OF 5-ARYL-4-(5-SUBSTITUTED-2-4- DIHYDROXYPHENYL)-1,2,3-THIADIAZOLE HSP90 INHIBITORS. | CHAPERONE, ATPASE
1xdf:B (ALA16) to (GLU44) CRYSTAL STRUCTURE OF PATHOGENESIS-RELATED PROTEIN LLPR-10.2A FROM YELLOW LUPINE | 7-STRANDED ANTIPARALLEL BETA-SHEET, KINKED C-TERMINAL ALPHA-HELIX, GLYCINE-RICH LOOP, PLANT PROTEIN
2nn2:A (HIS48) to (ASP78) CRYSTAL STRUCTURE OF THE BTB DOMAIN FROM THE LRF/ZBTB7 TRANSCRIPTIONAL REGULATOR | PROTEIN-PROTEIN INTERACTION DOMAIN, TRANSCRIPTION REPRESSOR, ZINC-FINGER PROTEIN, BTB DOMAIN, CANDIDATE ONCOPROTEIN, POZ DOMAIN
4a03:A (MET208) to (VAL241) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS DXR IN COMPLEX WITH THE ANTIBIOTIC FR900098 AND COFACTOR NADPH | OXIDOREDUCTASE, FR900098, MEP PATHWAY
2npp:C (ASP2) to (ARG49) STRUCTURE OF THE PROTEIN PHOSPHATASE 2A HOLOENZYME | HEAT REPEAT, SIGNALING PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2npp:F (ASP2) to (ARG49) STRUCTURE OF THE PROTEIN PHOSPHATASE 2A HOLOENZYME | HEAT REPEAT, SIGNALING PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3jdw:A (TYR103) to (PRO144) CRYSTAL STRUCTURE AND MECHANISM OF L-ARGININE: GLYCINE AMIDINOTRANSFERASE: A MITOCHONDRIAL ENZYME INVOLVED IN CREATINE BIOSYNTHESIS | TRANSFERASE, CREATINE BIOSYNTHESIS, CATALYTIC TRIAD, REACTION MECHANISM, NOVEL FOLD, FIVEFOLD PSEUDOSYMMETRY
2ykb:A (LYS191) to (GLU223) TRICYCLIC SERIES OF HSP90 INHIBITORS | CHAPERONE, INHIBITION
4o5g:B (ARG147) to (HIS180) DNA DOUBLE-STRAND BREAK REPAIR PATHWAY CHOICE IS DIRECTED BY DISTINCT MRE11 NUCLEASE ACTIVITIES | DNA REPAIR DNA DOUBLE-STRAND BREAK REPAIR THERMOPHILIC MRE11 NUCLEASE, DNA REPAIR DNA DOUBLE-STRAND BREAK REPAIR, DNA BINDING PROTEIN, DNA BINDING PROTEIN-INHIBITOR COMPLEX
2yoj:A (GLY188) to (ARG222) HCV NS5B POLYMERASE COMPLEXED WITH PYRIDONYLINDOLE COMPOUND | TRANSFERASE, INHIBITOR
2yoj:B (GLY188) to (ARG222) HCV NS5B POLYMERASE COMPLEXED WITH PYRIDONYLINDOLE COMPOUND | TRANSFERASE, INHIBITOR
5cf0:A (LYS191) to (LYS224) CRYSTAL STRUCTURE OF THE HUMAN HSP90-ALPHA N-DOMAIN BOUND TO THE HSP90 INHIBITOR FJ6 | HEAT SHOCK PROTEIN 90, N-TERMINAL DOMAIN, INHIBITOR, CHAPERONE- CHAPERONE INHIBITOR COMPLEX
5cga:B (GLY233) to (VAL262) STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH SUBSTRATE ANALOG 2-(1,3,5-TRIMETHYL-1H- PYRAZOLE-4-YL)ETHANOL | BACTERIAL THIAMINE BIOSYNTHESIS, HYDROXYETHYLTHIAZOLE KINASE, SUBSTRATE ANALOG, TRANSFERASE
5cga:C (GLY233) to (VAL262) STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH SUBSTRATE ANALOG 2-(1,3,5-TRIMETHYL-1H- PYRAZOLE-4-YL)ETHANOL | BACTERIAL THIAMINE BIOSYNTHESIS, HYDROXYETHYLTHIAZOLE KINASE, SUBSTRATE ANALOG, TRANSFERASE
5cga:F (GLY233) to (ILE259) STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH SUBSTRATE ANALOG 2-(1,3,5-TRIMETHYL-1H- PYRAZOLE-4-YL)ETHANOL | BACTERIAL THIAMINE BIOSYNTHESIS, HYDROXYETHYLTHIAZOLE KINASE, SUBSTRATE ANALOG, TRANSFERASE
5cga:H (GLY233) to (ILE259) STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH SUBSTRATE ANALOG 2-(1,3,5-TRIMETHYL-1H- PYRAZOLE-4-YL)ETHANOL | BACTERIAL THIAMINE BIOSYNTHESIS, HYDROXYETHYLTHIAZOLE KINASE, SUBSTRATE ANALOG, TRANSFERASE
5cge:B (GLY233) to (GLU261) STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH SUBSTRATE ANALOG 2-(2-METHYL-1H-IMIDAZOLE-1- YL)ETHANOL | BACTERIAL THIAMINE BIOSYNTHESIS, HYDROXYETHYLTHIAZOLE KINASE, SUBSTRATE ANALOG, TRANSFERASE
5cge:C (GLY233) to (VAL262) STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH SUBSTRATE ANALOG 2-(2-METHYL-1H-IMIDAZOLE-1- YL)ETHANOL | BACTERIAL THIAMINE BIOSYNTHESIS, HYDROXYETHYLTHIAZOLE KINASE, SUBSTRATE ANALOG, TRANSFERASE
5cge:F (GLY233) to (GLU261) STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH SUBSTRATE ANALOG 2-(2-METHYL-1H-IMIDAZOLE-1- YL)ETHANOL | BACTERIAL THIAMINE BIOSYNTHESIS, HYDROXYETHYLTHIAZOLE KINASE, SUBSTRATE ANALOG, TRANSFERASE
2yr1:A (PHE56) to (ILE85) CRYSTAL STRUCTURE OF 3-DEHYDROQUINATE DEHYDRATASE FROM GEOBACILLUS KAUSTOPHILUS HTA426 | AMINO ACID BIOSYNTHESIS, 3-DEHYDROQUINASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, LYASE
4obc:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV POLYMERASE NS5B GENOTYPE 2A JFH-1 ISOLATE WITH THE S15G, C223H, V321I RESISTANCE MUTATIONS AGAINST THE GUANOSINE ANALOG GS-0938 (PSI-3529238) | HEPATITIS, HCV, VIRAL POLYMERASE, RNA-DEPENDENT-RNA-POLYMERASE, RDRP, RESISTANCE, NUCLEOTIDE ANALOG INHIBITOR, VIRAL PROTEIN, TRANSFERASE
5cht:B (SER88) to (PRO117) CRYSTAL STRUCTURE OF USP18 | UBIQUITIN-SPECIFIC PROTEASE, ISG15, INTERFERON, HYDROLASE
5chv:A (SER88) to (THR118) CRYSTAL STRUCTURE OF USP18-ISG15 COMPLEX | UBIQUITIN-SPECIFIC PROTEASE, ISG15, INTERFERON, HYDROLASE
5chv:B (SER88) to (THR118) CRYSTAL STRUCTURE OF USP18-ISG15 COMPLEX | UBIQUITIN-SPECIFIC PROTEASE, ISG15, INTERFERON, HYDROLASE
2nyl:C (ASP2) to (ARG49) CRYSTAL STRUCTURE OF PROTEIN PHOSPHATASE 2A (PP2A) HOLOENZYME WITH THE CATALYTIC SUBUNIT CARBOXYL TERMINUS TRUNCATED | HEAT REPEAT, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2nyl:F (ASP2) to (ARG49) CRYSTAL STRUCTURE OF PROTEIN PHOSPHATASE 2A (PP2A) HOLOENZYME WITH THE CATALYTIC SUBUNIT CARBOXYL TERMINUS TRUNCATED | HEAT REPEAT, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2nym:C (ASP2) to (ARG49) CRYSTAL STRUCTURE OF PROTEIN PHOSPHATASE 2A (PP2A) WITH C-TERMINUS TRUNCATED CATALYTIC SUBUNIT | HEAT REPEAT, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2nym:F (ASP2) to (ARG49) CRYSTAL STRUCTURE OF PROTEIN PHOSPHATASE 2A (PP2A) WITH C-TERMINUS TRUNCATED CATALYTIC SUBUNIT | HEAT REPEAT, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ofc:F (GLU51) to (SER74) 2.0 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF HUMAN 2-AMINO-3- CARBOXYMUCONATE-6-SEMIALDEHYE DECARBOXYLASE | TIM-BARREL, DECARBOXYLASE, OXIDOREDUCTASE
3k30:A (MET38) to (THR63) HISTAMINE DEHYDROGENASE FROM NOCARDIODES SIMPLEX | 6-S-CYSTEINYL-FMN, ADP BINDING SITE, OXIDOREDUCTASE
5cm5:A (GLY233) to (GLU261) STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS | BACTERIAL THIAMINE BIOSYNTHESIS, HYDROXYETHYLTHIAZOLE KINASE, TRANSFERASE
5cm5:C (GLY233) to (GLU261) STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS | BACTERIAL THIAMINE BIOSYNTHESIS, HYDROXYETHYLTHIAZOLE KINASE, TRANSFERASE
5cm5:E (GLY233) to (GLU261) STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS | BACTERIAL THIAMINE BIOSYNTHESIS, HYDROXYETHYLTHIAZOLE KINASE, TRANSFERASE
5cm5:F (GLY233) to (GLU261) STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS | BACTERIAL THIAMINE BIOSYNTHESIS, HYDROXYETHYLTHIAZOLE KINASE, TRANSFERASE
2o1v:A (LYS252) to (TRP282) STRUCTURE OF FULL LENGTH GRP94 WITH ADP BOUND | GRP94, HSP82, HSP90, HTPG, CHAPERONE, ADP, GP96, ENDOPLASMIN,
2o1w:A (LYS252) to (TRP282) STRUCTURE OF N-TERMINAL PLUS MIDDLE DOMAINS (N+M) OF GRP94 | GRP94, HSP82, HSP90, HTPG, CHAPERONE, GP96, ENDOPLASMIN,
5coj:B (GLY233) to (GLU261) STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH NATIVE SUBSTRATE 2-(4-METHYL-1,3-THIAZOL-5- YL)ETHANOL. | BACTERIAL THIAMINE BIOSYNTHESIS, HYDROXYETHYLTHIAZOLE KINASE, TRANSFERASE, 2-(4-METHYL-1, 3-THIAZOL-5-YL)ETHANOL
5coj:C (GLY233) to (VAL262) STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH NATIVE SUBSTRATE 2-(4-METHYL-1,3-THIAZOL-5- YL)ETHANOL. | BACTERIAL THIAMINE BIOSYNTHESIS, HYDROXYETHYLTHIAZOLE KINASE, TRANSFERASE, 2-(4-METHYL-1, 3-THIAZOL-5-YL)ETHANOL
5cp8:A (THR196) to (LYS233) THE EFFECT OF ISOLEUCINE TO ALANINE MUTATION ON INHA ENZYME CRYSTALLIZATION PATTERN AND SUBSTRATE BINDING LOOP CONFORMATION AND FLEXIBILITY | CRYSTAL PACKING FATTY ACID BIOSYNTHESIS SLOW-ONSET INHIBITION FREE ENERGY CALCULATION, OXIDOREDUCTASE
5cpf:A (THR196) to (LYS233) COMPENSATION OF THE EFFECT OF ISOLEUCINE TO ALANINE MUTATION BY DESIGNED INHIBITION IN THE INHA ENZYME | FATTY ACID BIOSYNTHESIS INHIBITION SUBSTRATE BINDING LOOP CONFORMATION FREE ENERGY CALCULATION, OXIDOREDUCTASE
2o5d:A (GLY188) to (ARG222) THIAZOLONE-ACYLSULFONAMIDES AS NOVEL HCV NS5B POLYMERASE ALLOSTERIC INHIBITORS: CONVERGENCE OF STRUCTURE-BASED DRUG DESIGN AND X-RAY CRYSTALLOGRAPHIC STUDY | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, STRUCTURE- BASED DRUG DESIGN, VIRAL PROTEIN
2o5d:B (GLY188) to (ARG222) THIAZOLONE-ACYLSULFONAMIDES AS NOVEL HCV NS5B POLYMERASE ALLOSTERIC INHIBITORS: CONVERGENCE OF STRUCTURE-BASED DRUG DESIGN AND X-RAY CRYSTALLOGRAPHIC STUDY | HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, STRUCTURE- BASED DRUG DESIGN, VIRAL PROTEIN
1xld:A (PRO96) to (GLY137) MECHANISM FOR ALDOSE-KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE INVOLVING RING OPENING FOLLOWED BY A 1,2-HYDRIDE SHIFT | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
1xld:B (PRO96) to (GLY137) MECHANISM FOR ALDOSE-KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE INVOLVING RING OPENING FOLLOWED BY A 1,2-HYDRIDE SHIFT | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
1xlf:B (PRO96) to (GLY137) MECHANISM FOR ALDOSE-KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE INVOLVING RING OPENING FOLLOWED BY A 1,2-HYDRIDE SHIFT | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
1xlg:B (PRO96) to (GLY137) MECHANISM FOR ALDOSE-KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE INVOLVING RING OPENING FOLLOWED BY A 1,2-HYDRIDE SHIFT | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
1xlh:A (PRO96) to (GLY137) MECHANISM FOR ALDOSE-KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE INVOLVING RING OPENING FOLLOWED BY A 1,2-HYDRIDE SHIFT | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
1xli:B (PRO96) to (GLY137) MECHANISM FOR ALDOSE-KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE INVOLVING RING OPENING FOLLOWED BY A 1,2-HYDRIDE SHIFT | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
2o7p:A (MSE128) to (SER156) THE CRYSTAL STRUCTURE OF RIBD FROM ESCHERICHIA COLI IN COMPLEX WITH THE OXIDISED NADP+ COFACTOR IN THE ACTIVE SITE OF THE REDUCTASE DOMAIN | NADP+ COMPLEX, ALPHA AND BETA CLASS WITH MAINLY PARALLELL BETA STRANDS, STRUCTURAL GENOMICS, HTP-PROTEIN ESCHERICHIA COLI, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, HYDROLASE, OXIDOREDUCTASE
2o8a:A (ILE9) to (GLU56) RAT PP1CGAMMA COMPLEXED WITH MOUSE INHIBITOR-2 | PROTEIN PHOSPHATASE, INHIBITOR-2, HYDROLASE-INHIBITOR COMPLEX
3kaj:A (LEU179) to (GLN238) APOENZYME STRUCTURE OF HOMOGLUTATHIONE SYNTHETASE FROM GLYCINE MAX IN OPEN CONFORMATION | DIMER, ATP-GRASP DOMAIN, LIGASE
1m34:D (THR119) to (CYS153) NITROGENASE COMPLEX FROM AZOTOBACTER VINELANDII STABILIZED BY ADP- TETRAFLUOROALUMINATE | NITROGENASE, NITROGEN FIXATION, SIGNAL TRANSDUCTION, ELECTRON TRANSFER, ATP HYDROLYSIS, COMPLEX OF NITROGENASE PROTEINS, OXIDOREDUCTASE
1m34:J (THR119) to (CYS153) NITROGENASE COMPLEX FROM AZOTOBACTER VINELANDII STABILIZED BY ADP- TETRAFLUOROALUMINATE | NITROGENASE, NITROGEN FIXATION, SIGNAL TRANSDUCTION, ELECTRON TRANSFER, ATP HYDROLYSIS, COMPLEX OF NITROGENASE PROTEINS, OXIDOREDUCTASE
3kcf:C (THR176) to (GLU209) CRYSTAL STRUCTURE OF TGFBRI COMPLEXED WITH A PYRAZOLONE INHIBITOR | KINASE, TGFBETARI, STRUCTURE-BASED DRUG DESIGN, PROTEIN- INHIBITOR COMPLEX, AORTIC ANEURYSM, ATP-BINDING, CRANIOSYNOSTOSIS, DISEASE MUTATION, DISULFIDE BOND, GLYCOPROTEIN, MAGNESIUM, MANGANESE, MEMBRANE, METAL- BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, POLYMORPHISM, RECEPTOR, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, TRANSMEMBRANE
4ooe:D (MET208) to (VAL241) M. TUBERCULOSIS 1-DEOXY-D-XYLULOSE-5-PHOSPHATE REDUCTOISOMERASE W203Y MUTANT BOUND TO FOSMIDOMYCIN AND NADPH | REDUCTOISOMERASE, OXIDOREDUCTASE-ANTIBIOTIC COMPLEX
2zku:A (GLY188) to (ARG222) STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM | HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE
2zku:B (GLY188) to (ARG222) STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM | HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE
2zku:C (GLY188) to (ARG222) STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM | HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE
5cx1:D (THR119) to (SER150) NITROGENASE MOLYBDENUM-IRON PROTEIN BETA-K400E MUTANT | NITROGEN FIXATION, OXIDOREDUCTASE
5cx1:H (THR119) to (SER150) NITROGENASE MOLYBDENUM-IRON PROTEIN BETA-K400E MUTANT | NITROGEN FIXATION, OXIDOREDUCTASE
5cx1:L (THR119) to (SER150) NITROGENASE MOLYBDENUM-IRON PROTEIN BETA-K400E MUTANT | NITROGEN FIXATION, OXIDOREDUCTASE
3kg6:B (THR1879) to (PRO1914) DEHYDRATASE DOMAIN FROM CURF MODULE OF CURACIN POLYKETIDE SYNTHASE | POLYKETIDE SYNTHASE, DOUBLE HOTDOG FOLD, DEHYDRATASE, LYASE
3khy:B (MSE275) to (GLY321) CRYSTAL STRUCTURE OF A PROPIONATE KINASE FROM FRANCISELLA TULARENSIS SUBSP. TULARENSIS SCHU S4 | PROPIONATE KINASE, CSGID, IDP01739, ATP-BINDING, KINASE, NUCLEOTIDE- BINDING, TRANSFERASE, STRUCTURAL GENOMICS, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, NATIONAL INSTITUTES OF HEALTH, DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES
1xyb:A (PRO96) to (GLY137) X-RAY CRYSTALLOGRAPHIC STRUCTURES OF D-XYLOSE ISOMERASE-SUBSTRATE COMPLEXES POSITION THE SUBSTRATE AND PROVIDE EVIDENCE FOR METAL MOVEMENT DURING CATALYSIS | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
1xym:A (PRO96) to (GLY137) THE ROLE OF THE DIVALENT METAL ION IN SUGAR BINDING, RING OPENING, AND ISOMERIZATION BY D-XYLOSE ISOMERASE: REPLACEMENT OF A CATALYTIC METAL BY AN AMINO-ACID | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
4oxk:A (MET199) to (LYS233) MULTIPLE BINDING MODES OF INHIBITOR PT155 TO THE MYCOBACTERIUM TUBERCULOSIS ENOYL-ACP REDUCTASE INHA WITHIN A TETRAMER | BACTERIAL FATTY ACID BIOSYNTHESIS, CONFORMATIONAL PROFILE OF ENZYME- INHIBITOR COMPLEX, INHIBITION KINETICS, SUBSTRATE-BINDING LOOP REFOLDING, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4oxk:C (MET199) to (LYS233) MULTIPLE BINDING MODES OF INHIBITOR PT155 TO THE MYCOBACTERIUM TUBERCULOSIS ENOYL-ACP REDUCTASE INHA WITHIN A TETRAMER | BACTERIAL FATTY ACID BIOSYNTHESIS, CONFORMATIONAL PROFILE OF ENZYME- INHIBITOR COMPLEX, INHIBITION KINETICS, SUBSTRATE-BINDING LOOP REFOLDING, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4oxk:D (MET199) to (LYS233) MULTIPLE BINDING MODES OF INHIBITOR PT155 TO THE MYCOBACTERIUM TUBERCULOSIS ENOYL-ACP REDUCTASE INHA WITHIN A TETRAMER | BACTERIAL FATTY ACID BIOSYNTHESIS, CONFORMATIONAL PROFILE OF ENZYME- INHIBITOR COMPLEX, INHIBITION KINETICS, SUBSTRATE-BINDING LOOP REFOLDING, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4aex:B (GLY188) to (ARG222) HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 2.4 ANGSTROM IN A PRIMITIVE ORTHORHOMBIC SPACE GROUP | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
4ag0:A (PRO489) to (SER535) CRYSTAL STRUCTURE OF FIMX EAL DOMAIN | HYDROLASE, PHOSPHODIESTERASE, C-DIGMP, BIOFILM
4ag0:B (PRO490) to (SER535) CRYSTAL STRUCTURE OF FIMX EAL DOMAIN | HYDROLASE, PHOSPHODIESTERASE, C-DIGMP, BIOFILM
4ag0:B (SER535) to (SER567) CRYSTAL STRUCTURE OF FIMX EAL DOMAIN | HYDROLASE, PHOSPHODIESTERASE, C-DIGMP, BIOFILM
2zyl:A (ASN168) to (THR191) CRYSTAL STRUCTURE OF 3-KETOSTEROID-9-ALPHA-HYDROXYLASE (KSHA) FROM M. TUBERCULOSIS | KSHA, CHOLESTEROL, RIESKE, OXIDOREDUCTASE
3a06:A (ARG195) to (GLU231) CRYSTAL STRUCTURE OF DXR FROM THERMOOGA MARITIA, IN COMPLEX WITH FOSMIDOMYCIN AND NADPH | REDUCTOISOMERASE, MEP PATHWAY, ISOPRENE BIOSYNTHESIS, METAL-BINDING, NADP, OXIDOREDUCTASE
3a14:A (ARG195) to (ILE228) CRYSTAL STRUCTURE OF DXR FROM THERMOTOGA MARITIMA, IN COMPLEX WITH NADPH | REDUCTOISOMERASE, MEP PATHWAY, ISOPRENE BIOSYNTHESIS, METAL-BINDING, NADP, OXIDOREDUCTASE
3a14:B (ARG195) to (ILE228) CRYSTAL STRUCTURE OF DXR FROM THERMOTOGA MARITIMA, IN COMPLEX WITH NADPH | REDUCTOISOMERASE, MEP PATHWAY, ISOPRENE BIOSYNTHESIS, METAL-BINDING, NADP, OXIDOREDUCTASE
1mru:A (ASP45) to (GLU81) INTRACELLULAR SER/THR PROTEIN KINASE DOMAIN OF MYCOBACTERIUM TUBERCULOSIS PKNB. | REGULATORY, ATP-RECOGNITION, MOLECULAR EVOLUTION, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
4p7l:A (LEU493) to (ASN538) STRUCTURE OF ESCHERICHIA COLI PGAB C-TERMINAL DOMAIN, P212121 CRYSTAL FORM | BETA ALPHA BARREL, CARBOHYDRATE BINDING, GLYCOSYL HYDROLASE FOLD
4p7o:A (LEU493) to (ASN538) STRUCTURE OF ESCHERICHIA COLI PGAB C-TERMINAL DOMAIN, P1 CRYSTAL FORM | BETA ALPHA BARREL, CARBOHYDRATE BINDING, GLYCOSYL HYDROLASE FOLD, HYDROLASE
4p7o:B (SER492) to (ASN538) STRUCTURE OF ESCHERICHIA COLI PGAB C-TERMINAL DOMAIN, P1 CRYSTAL FORM | BETA ALPHA BARREL, CARBOHYDRATE BINDING, GLYCOSYL HYDROLASE FOLD, HYDROLASE
4p7q:A (SER492) to (ASN538) STRUCTURE OF ESCHERICHIA COLI PGAB C-TERMINAL DOMAIN IN COMPLEX WITH N-ACETYLGLUCOSAMINE | BETA ALPHA BARREL, CARBOHYDRATE BINDING, GLYCOSYL HYDROLASE FOLD, COMPLEX, HYDROLASE
4p8w:A (ARG237) to (TYR269) THE CRYSTAL STRUCTURES OF YKL-39 IN THE PRESENCE OF CHITOOLIGOSACCHARIDES (GLCNAC4) WERE SOLVED TO RESOLUTIONS OF 1.9 ANGSTROM | CHITINASE 3-LIKE PROTEIN 2, HUMAN YKL-39, FAMILY-18 CHITINASE
5dad:A (LYS97) to (GLY127) CRYSTAL STRUCTURE OF HUMAN KEAP1 BTB DOMAIN IN COMPLEX WITH SMALL MOLECULE TX64014 | KEAP1, TRASCRIPTION REGULATION, BTB DOMAIN, CYSTEINE MODIFICATION, C1-(R)-CYS151 ADDUCT, TRANSCRIPTION
1n2c:B (THR119) to (SER150) NITROGENASE COMPLEX FROM AZOTOBACTER VINELANDII STABILIZED BY ADP-TETRAFLUOROALUMINATE | NITROGENASE, NITROGEN FIXATION, SIGNAL TRANSDUCTION, ELECTRON TRANSFER, ATP HYDROLYSIS, COMPLEX OF NITROGENASE PROTEINS
1n2c:D (THR119) to (SER150) NITROGENASE COMPLEX FROM AZOTOBACTER VINELANDII STABILIZED BY ADP-TETRAFLUOROALUMINATE | NITROGENASE, NITROGEN FIXATION, SIGNAL TRANSDUCTION, ELECTRON TRANSFER, ATP HYDROLYSIS, COMPLEX OF NITROGENASE PROTEINS
3abz:B (VAL6) to (ILE33) CRYSTAL STRUCTURE OF SE-MET LABELED BETA-GLUCOSIDASE FROM KLUYVEROMYCES MARXIANUS | GLYCOSIDE HYDROLASE FAMILY3 BETA-GLUCOSIDASE, PA14 DOMAIN, HYDROLASE
4pgl:C (ASP74) to (LEU108) CRYSTAL STRUCTURE OF ENGINEERED D-TAGATOSE 3-EPIMERASE PCDTE-ILS6 | EPIMERASE, TIM-BARREL, ISOMERASE
1n3b:B (ARG68) to (VAL111) CRYSTAL STRUCTURE OF DEPHOSPHOCOENZYME A KINASE FROM ESCHERICHIA COLI | TRIMER, P-LOOP, ALPHA/BETA, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, STRUCTURAL GENOMICS, TRANSFERASE
1n3b:C (ARG67) to (VAL111) CRYSTAL STRUCTURE OF DEPHOSPHOCOENZYME A KINASE FROM ESCHERICHIA COLI | TRIMER, P-LOOP, ALPHA/BETA, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, STRUCTURAL GENOMICS, TRANSFERASE
3l0k:A (SER2) to (ALA34) HUMAN OROTIDYL-5'-MONOPHOSPHATE DECARBOXYLASE IN COMPLEX WITH 6-ACETYL-UMP | DECARBOXYLASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS
3l0k:B (SER2) to (ALA34) HUMAN OROTIDYL-5'-MONOPHOSPHATE DECARBOXYLASE IN COMPLEX WITH 6-ACETYL-UMP | DECARBOXYLASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS
3aes:A (GLU75) to (LEU108) STRUCTURE OF THE LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE CATALYZING A KEY REDUCTION FOR GREENING IN THE DARK | IRON/SULFUR CLUSTER, BACTERIOCHLOROPHYLL BIOSYNTHESIS, CHLOROPHYLL BIOSYNTHESIS, OXIDOREDUCTASE, PHOTOSYNTHESIS
1yuy:A (GLY188) to (ARG222) HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2A | NS5B POLYMERASE GENOTYPE 2A, VIRAL PROTEIN
1yv2:A (GLY188) to (ARG222) HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2A | NS5B POLYMERASE GENOTYPE 2A, TRANSFERASE
1yvz:A (GLY188) to (ARG222) HEPATITIS C VIRUS RNA POLYMERASE GENOTYPE 2A IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | NS5B POLYMERASE GENOTYPE 2A, NON-NUCLEOSIDE INHIBITOR, VIRAL PROTEIN
1yzy:A (ASP275) to (TYR306) CRYSTAL STRUCTURE OF HAEMOPHILUS INFLUENZAE PROTEIN HI1011, PFAM DUF1537 | PUTATIVE TRNA SYNTHASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, UNKNOWN FUNCTION
1yzy:B (ASP275) to (ALA307) CRYSTAL STRUCTURE OF HAEMOPHILUS INFLUENZAE PROTEIN HI1011, PFAM DUF1537 | PUTATIVE TRNA SYNTHASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, UNKNOWN FUNCTION
4pmu:A (PHE294) to (VAL333) CRYSTAL STRUCTURE OF A NOVEL REDUCING-END XYLOSE-RELEASING EXO- OLIGOXYLANASE (XYNA) BELONGING TO GH10 FAMILY (SPACE GROUP P1211) | GLYCOSIDE HYDROLASE, HYDROLASE
4pmu:F (PHE294) to (TRP334) CRYSTAL STRUCTURE OF A NOVEL REDUCING-END XYLOSE-RELEASING EXO- OLIGOXYLANASE (XYNA) BELONGING TO GH10 FAMILY (SPACE GROUP P1211) | GLYCOSIDE HYDROLASE, HYDROLASE
4pmh:A (THR112) to (LYS155) THE STRUCTURE OF RICE WEEVIL PECTIN METHYL ESTERASE | BETA-BARREL, PECTIN METHYL ESTERASE, HYDROLASE
1z6r:B (SER342) to (SER375) CRYSTAL STRUCTURE OF MLC FROM ESCHERICHIA COLI | TRANSCRIPTIONAL REPRESSOR, ROK FAMILY PROTEIN, DNA BINDING PROTEIN, HELIX-TURN-HELIX, PHOSPHOTRANSFERASE SYSTEM, METALLOPROTEIN, TRANSCRIPTION
1z6r:C (SER342) to (GLU374) CRYSTAL STRUCTURE OF MLC FROM ESCHERICHIA COLI | TRANSCRIPTIONAL REPRESSOR, ROK FAMILY PROTEIN, DNA BINDING PROTEIN, HELIX-TURN-HELIX, PHOSPHOTRANSFERASE SYSTEM, METALLOPROTEIN, TRANSCRIPTION
1z6r:D (SER342) to (GLU374) CRYSTAL STRUCTURE OF MLC FROM ESCHERICHIA COLI | TRANSCRIPTIONAL REPRESSOR, ROK FAMILY PROTEIN, DNA BINDING PROTEIN, HELIX-TURN-HELIX, PHOSPHOTRANSFERASE SYSTEM, METALLOPROTEIN, TRANSCRIPTION
4psf:B (ASN95) to (ASN137) PIH1D1 N-TERMINAL DOMAIN | ALPHA, BETA, PHOSPHO-BINDING, TEL2, PHOSPHORYLATION, PROTEIN BINDING
4psi:B (ASN125) to (MSE165) PIH1D1/PHOSPHO-TEL2 COMPLEX | ALPHA, BETA, PHOSPHO-BINDING, TEL2, PHSOPHORYLATION, PROTEIN BINDING
5drv:A (SER7) to (GLY43) CRYSTAL STRUCTURE OF THE G3BP2 NTF2-LIKE DOMAIN IN COMPLEX WITH A PEPTIDE | NTF2-LIKE, G3BP, PEPTIDE COMPLEX, PROTEIN BINDING
4pxh:C (PRO267) to (ALA294) STRUCTURE OF P450SKY (CYP163B3), A CYTOCHROME P450 FROM SKYLLAMYCIN BIOSYNTHESIS IN COMPLEX WITH A PEPTIDYL CARRIER PROTEIN DOMAIN | CYTOCHROME P450 FOLD, BETA-AMINOACYL CARRIER PROTEIN HYDROXYLASE, PEPTIDYL CARRIER PROTEIN DOMAINS, SKYLLAMYCIN NRPS, OXIDOREDUCTASE- PROTEIN BINDING COMPLEX
1zid:A (THR196) to (LYS233) LONG FATTY ACID CHAIN ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH AN ISONICOTINIC-ACYL-NADH INHIBITOR | OXIDOREDUCTASE, INHA ENZYME, ISONIAZID, MODIFIED NADH, ENOYL-ACP REDUCTASE, TUBERCULOSIS, MYCOLIC ACID BIOSYNTHESIS, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC
3lnb:A (SER52) to (ASP96) CRYSTAL STRUCTURE ANALYSIS OF ARYLAMINE N-ACETYLTRANSFERASE C FROM BACILLUS ANTHRACIS | ARYLAMINE N-ACETYLTRANSFERASE, TRANSFERASE, NAT, ACETYLTRANSFERASE, ACYLTRANSFERASE
1zow:A (GLY184) to (HIS238) CRYSTAL STRUCTURE OF S. AUREUS FABH, BETA-KETOACYL CARRIER PROTEIN SYNTHASE III | FABH, FATTY ACID BIOSYNTHESIS, TRANSFERASE
1zow:B (GLY184) to (HIS238) CRYSTAL STRUCTURE OF S. AUREUS FABH, BETA-KETOACYL CARRIER PROTEIN SYNTHASE III | FABH, FATTY ACID BIOSYNTHESIS, TRANSFERASE
1zow:C (GLY184) to (HIS238) CRYSTAL STRUCTURE OF S. AUREUS FABH, BETA-KETOACYL CARRIER PROTEIN SYNTHASE III | FABH, FATTY ACID BIOSYNTHESIS, TRANSFERASE
1zw9:A (LYS178) to (THR210) YEAST HSP82 IN COMPLEX WITH THE NOVEL HSP90 INHIBITOR 8-(6-BROMO- BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE | HSP82, HSP90, GRP94, HTPG, CHAPERONE, LIGAND, ADENOSINE
4awp:B (LYS191) to (GLU223) COMPLEX OF HSP90 ATPASE DOMAIN WITH TROPANE DERIVED INHIBITORS | CHAPERONE, INHIBITOR
4ay1:A (ARG237) to (TYR269) HUMAN YKL-39 IS A PSEUDO-CHITINASE WITH RETAINED CHITOOLIGOSACCHARIDE BINDING PROPERTIES | CHILECTIN, LECTIN, CHITOOLIGOSACCHARIDE, PSEUDOCHITINASE, HYDROLASE
4ay1:D (ARG237) to (TYR269) HUMAN YKL-39 IS A PSEUDO-CHITINASE WITH RETAINED CHITOOLIGOSACCHARIDE BINDING PROPERTIES | CHILECTIN, LECTIN, CHITOOLIGOSACCHARIDE, PSEUDOCHITINASE, HYDROLASE
4ay1:E (ARG237) to (TYR269) HUMAN YKL-39 IS A PSEUDO-CHITINASE WITH RETAINED CHITOOLIGOSACCHARIDE BINDING PROPERTIES | CHILECTIN, LECTIN, CHITOOLIGOSACCHARIDE, PSEUDOCHITINASE, HYDROLASE
4ay1:G (ARG237) to (TYR269) HUMAN YKL-39 IS A PSEUDO-CHITINASE WITH RETAINED CHITOOLIGOSACCHARIDE BINDING PROPERTIES | CHILECTIN, LECTIN, CHITOOLIGOSACCHARIDE, PSEUDOCHITINASE, HYDROLASE
4ay1:I (ARG237) to (TYR269) HUMAN YKL-39 IS A PSEUDO-CHITINASE WITH RETAINED CHITOOLIGOSACCHARIDE BINDING PROPERTIES | CHILECTIN, LECTIN, CHITOOLIGOSACCHARIDE, PSEUDOCHITINASE, HYDROLASE
4ay1:L (ARG237) to (TYR269) HUMAN YKL-39 IS A PSEUDO-CHITINASE WITH RETAINED CHITOOLIGOSACCHARIDE BINDING PROPERTIES | CHILECTIN, LECTIN, CHITOOLIGOSACCHARIDE, PSEUDOCHITINASE, HYDROLASE
1zyk:D (MET157) to (PHE193) ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH PRPP, ANTHRANILATE AND MAGNESIUM | ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE, PRPP, ANTHRANILATE, TRPD
3aua:A (LYS300) to (VAL334) CRYSTAL STRUCTURE OF THE QUATERNARY COMPLEX-2 OF AN ISOMERASE | NADPH BINDING, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
4b3j:A (ASP69) to (ALA107) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FATTY ACID BETA-OXIDATION COMPLEX WITH COENZYMEA BOUND AT THE HYDRATASE AND THIOLASE ACTIVE SITES | OXIDOREDUCTASE-TRANSFERASE COMPLEX, TFE, TRIFUNCTIONAL ENZYME, HYDRATASE
3m4p:A (ASN384) to (GLY422) ENTAMOEBA HISTOLYTICA ASPARAGINYL-TRNA SYNTHETASE (ASNRS) IN COMPLEX WITH ASPARAGINYL-ADENYLATE | AMINOACYL-TRNA SYNTHETASE, TRNA LIGASE, AARS, ASNRS, TRANSLATION, ATP-BINDING, NUCLEOTIDE-BINDING, STRUCTURAL GENOMICS, MEDICAL STRUCTURAL GENOMICS OF PATHOGENIC PROTOZOA, MSGPP, LIGASE, PROTEIN BIOSYNTHESIS
3m4p:C (ASN384) to (GLY422) ENTAMOEBA HISTOLYTICA ASPARAGINYL-TRNA SYNTHETASE (ASNRS) IN COMPLEX WITH ASPARAGINYL-ADENYLATE | AMINOACYL-TRNA SYNTHETASE, TRNA LIGASE, AARS, ASNRS, TRANSLATION, ATP-BINDING, NUCLEOTIDE-BINDING, STRUCTURAL GENOMICS, MEDICAL STRUCTURAL GENOMICS OF PATHOGENIC PROTOZOA, MSGPP, LIGASE, PROTEIN BIOSYNTHESIS
4b6z:C (ASN216) to (HIS268) CRYSTAL STRUCTURE OF METALLO-CARBOXYPEPTIDASE FROM BURKHOLDERIA CENOCEPACIA | HYDROLASE
3b28:B (LYS191) to (GLU225) HSP90 ALPHA N-TERMINAL DOMAIN IN COMPLEX WITH AN INHIBITOR CH5015765 | CHAPERONE-CHAPERONE INHIBITOR COMPLEX
3m97:X (PHE35) to (LEU60) STRUCTURE OF THE SOLUBLE DOMAIN OF CYTOCHROME C552 WITH ITS FLEXIBLE LINKER SEGMENT FROM PARACOCCUS DENITRIFICANS | ELECTRON TRANSPORT CHAIN (CYTOCHROME), ELECTRON TRANSFER, P. DENITRIFICANS, ELECTRON DONOR, CELL MEMBRANE, ELECTRON TRANSPORT, HEME, IRON, MEMBRANE, METAL-BINDING, TRANSMEMBRANE, TRANSPORT
4bax:D (ASP48) to (PRO66) CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM STREPTOMYCES COELICOLOR | LIGASE
3mdy:A (SER175) to (LYS208) CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF THE BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B (BMPR1B) IN COMPLEX WITH FKBP12 AND LDN- 193189 | COMPLEX (ISOMERASE-PROTEIN KINASE), RECEPTOR SERINE/THREONINE KINASE, STRUCTURAL GENOMICS CONSORTIUM, SGC, ATP-BINDING, DISEASE MUTATION, KINASE, TRANSFERASE, ROTAMASE, TRANSFERASE-ISOMERASE COMPLEX
2afh:B (THR119) to (SER150) CRYSTAL STRUCTURE OF NUCLEOTIDE-FREE AV2-AV1 COMPLEX | NITROGEN FIXATION, IRON-SULFUR, METAL-BINDING, MOLYBDENUM, OXIDOREDUCTASE
2afi:B (THR119) to (CYS153) CRYSTAL STRUCTURE OF MGADP BOUND AV2-AV1 COMPLEX | NITROGEN FIXATION, IRON-SULFUR, METAL-BINDING, MOLYBDENUM, OXIDOREDUCTASE
2afi:D (THR119) to (CYS153) CRYSTAL STRUCTURE OF MGADP BOUND AV2-AV1 COMPLEX | NITROGEN FIXATION, IRON-SULFUR, METAL-BINDING, MOLYBDENUM, OXIDOREDUCTASE
2afi:L (THR119) to (CYS153) CRYSTAL STRUCTURE OF MGADP BOUND AV2-AV1 COMPLEX | NITROGEN FIXATION, IRON-SULFUR, METAL-BINDING, MOLYBDENUM, OXIDOREDUCTASE
3mf5:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH AMIDE BIOISOSTERE THUMB SITE INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE
3mf5:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH AMIDE BIOISOSTERE THUMB SITE INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE
3mkv:G (ASN72) to (ALA106) CRYSTAL STRUCTURE OF AMIDOHYDROLASE EAJ56179 | SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, PROLIDASE, HYDROLASE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
4bge:A (THR196) to (LYS233) CRYSTAL STRUCTURE OF INHA(S94A) MUTANT IN COMPLEX WITH PYRIDOMYCIN | OXIDOREDUCTASE
4bge:B (THR196) to (LYS233) CRYSTAL STRUCTURE OF INHA(S94A) MUTANT IN COMPLEX WITH PYRIDOMYCIN | OXIDOREDUCTASE
4bge:F (THR196) to (LYS233) CRYSTAL STRUCTURE OF INHA(S94A) MUTANT IN COMPLEX WITH PYRIDOMYCIN | OXIDOREDUCTASE
4bgi:A (THR196) to (LYS233) CRYSTAL STRUCTURE OF INHA(S94A) MUTANT IN COMPLEX WITH OH-141 | OXIDOREDUCTASE, TUBERCULOSIS DRUG
4bgi:B (THR196) to (LYS233) CRYSTAL STRUCTURE OF INHA(S94A) MUTANT IN COMPLEX WITH OH-141 | OXIDOREDUCTASE, TUBERCULOSIS DRUG
4bgi:F (THR196) to (LYS233) CRYSTAL STRUCTURE OF INHA(S94A) MUTANT IN COMPLEX WITH OH-141 | OXIDOREDUCTASE, TUBERCULOSIS DRUG
3mpd:B (PRO10) to (CYS37) CRYSTAL STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE FROM ENCEPHALITOZOON CUNICULI, CUBIC FORM, APO | SSGCID, NIH, NIAID, SBRI, UW, EMERALD BIOSTRUCTURES, ENCEPHALITOZOON CUNICULI, KINASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
3bk0:A (SER37) to (ALA69) CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 5-CN-UMP | UMP SYNTHASE, C-TERMINAL DOMAIN, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, HUMAN, 5-CN-UMP, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
4bls:C (ASP6) to (GLY50) P4 PROTEIN FROM BACTERIOPHAGE PHI12 Q278A MUTANT IN COMPLEX WITH AMPCPP | HYDROLASE, PACKAGING, CYSTOVIRIDAE
5f1y:A (SER58) to (ILE88) CRYSTAL STRUCTURE OF BA3275, THE MEMBER OF S66 FAMILY OF SERINE PEPTIDASES | MCCC FAMILY PROTEIN, SERINE PEPTIDASE, HYDROLASE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, STRUCTURAL GENOMICS
5f1y:B (SER58) to (ILE88) CRYSTAL STRUCTURE OF BA3275, THE MEMBER OF S66 FAMILY OF SERINE PEPTIDASES | MCCC FAMILY PROTEIN, SERINE PEPTIDASE, HYDROLASE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, STRUCTURAL GENOMICS
3br9:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, CYTOPLASM, HOST- VIRUS INTERACTION, ANTIVIRAL, VIRAL NUCLEOPROTEIN, HYDROLASE
3br9:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, CYTOPLASM, HOST- VIRUS INTERACTION, ANTIVIRAL, VIRAL NUCLEOPROTEIN, HYDROLASE
3bsa:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN
3bsa:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN
4qxm:A (LEU197) to (LYS233) CRYSTAL STRUCTURE OF THE INHA:GSK_SB713 COMPLEX | ROSSMAN FOLD, ENOYL-ACP REDUCTASE, NADH BINDING, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
4qxm:C (LEU197) to (LYS233) CRYSTAL STRUCTURE OF THE INHA:GSK_SB713 COMPLEX | ROSSMAN FOLD, ENOYL-ACP REDUCTASE, NADH BINDING, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3mwv:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE | HCV VIRUS RDRP NS5B POLYMERASE, TRANSFERASE
3mww:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE | HCV VIRUS RDRP NS5B POLYMERASE INHIBITOR, TRANSFERASE
5f5x:A (SER58) to (ILE88) CRYSTAL STRUCTURE OF S116A BA3275 WITH AMP BOUND | MCCF, SERINE PEPTIDASE, HYDROLASE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, STRUCTURAL GENOMICS
5f5x:B (SER58) to (ILE88) CRYSTAL STRUCTURE OF S116A BA3275 WITH AMP BOUND | MCCF, SERINE PEPTIDASE, HYDROLASE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, STRUCTURAL GENOMICS
5f7r:E (HIS291) to (GLY337) ROK REPRESSOR LMO0178 FROM LISTERIA MONOCYTOGENES BOUND TO INDUCER | REPRESSOR, OPEN READING FRAME, KINASE, STRUCTURAL GENOMICS, PSI- BIOLOGY, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, TRANSCRIPTION
5f7r:A (HIS291) to (GLY337) ROK REPRESSOR LMO0178 FROM LISTERIA MONOCYTOGENES BOUND TO INDUCER | REPRESSOR, OPEN READING FRAME, KINASE, STRUCTURAL GENOMICS, PSI- BIOLOGY, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, TRANSCRIPTION
4bqr:A (THR196) to (LYS233) COMPLEX WITH METHYL-THIAZOLE COMPOUND 11 | OXIDOREDUCTASE, METHYL-THIAZOLE
4bqr:D (LEU197) to (LYS233) COMPLEX WITH METHYL-THIAZOLE COMPOUND 11 | OXIDOREDUCTASE, METHYL-THIAZOLE
4bqz:A (ALA123) to (GLY156) RAT NTPDASE2 IN COMPLEX WITH MG GMPPNP | HYDROLASE, APYRASE, ATPASE, ADPASE, CD39, PURINERGIC SIGNALLING, DOMAIN ROTATION, TRANSITION STATE, NTPDASE
4br0:A (ALA123) to (GLY156) RAT NTPDASE2 IN COMPLEX WITH CA AMPNP | HYDROLASE, APYRASE, ATPASE, ADPASE, PURINERGIC SIGNALLING, DOMAIN ROTATION, TRANSITION STATE, NTPDASE
5f9m:A (GLY57) to (ILE88) CRYSTAL STRUCTURE OF NATIVE B3275, MEMBER OF MCCF FAMILY OF ENZYMES | SERINE PEPTIDASE, MCCF RELATED PROTEIN, HYDROLASE, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
3n2c:B (ASN72) to (ARG104) CRYSTAL STRUCTURE OF PROLIDASE EAH89906 COMPLEXED WITH N- METHYLPHOSPHONATE-L-PROLINE | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, PROLIDASE, NYSGXRC, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, HYDROLASE
3n2c:C (ASN72) to (ARG104) CRYSTAL STRUCTURE OF PROLIDASE EAH89906 COMPLEXED WITH N- METHYLPHOSPHONATE-L-PROLINE | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, PROLIDASE, NYSGXRC, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, HYDROLASE
3n2c:I (ASN72) to (ARG104) CRYSTAL STRUCTURE OF PROLIDASE EAH89906 COMPLEXED WITH N- METHYLPHOSPHONATE-L-PROLINE | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, PROLIDASE, NYSGXRC, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, HYDROLASE
3n2c:L (ASN72) to (ARG104) CRYSTAL STRUCTURE OF PROLIDASE EAH89906 COMPLEXED WITH N- METHYLPHOSPHONATE-L-PROLINE | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, PROLIDASE, NYSGXRC, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, HYDROLASE
3n2c:M (ASN72) to (ARG104) CRYSTAL STRUCTURE OF PROLIDASE EAH89906 COMPLEXED WITH N- METHYLPHOSPHONATE-L-PROLINE | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, PROLIDASE, NYSGXRC, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, HYDROLASE
3n2c:O (LEU73) to (ARG104) CRYSTAL STRUCTURE OF PROLIDASE EAH89906 COMPLEXED WITH N- METHYLPHOSPHONATE-L-PROLINE | UNKNOWN SOURCE, AMIDOHYDROLASE, SARGASSO SEA, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, PROLIDASE, NYSGXRC, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, HYDROLASE
3n2e:B (ARG116) to (ARG147) CRYSTAL STRUCTURE OF HELICOBACTOR PYLORI SHIKIMATE KINASE IN COMPLEX WITH NSC162535 | ALPHA-BETA-ALPHA FOLD, TRANSFERASE
3n3t:A (PRO538) to (ASN584) CRYSTAL STRUCTURE OF PUTATIVE DIGUANYLATE CYCLASE/PHOSPHODIESTERASE COMPLEX WITH CYCLIC DI-GMP | GGDEF & EAL DOMAINS, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
5fg3:A (PHE157) to (LEU192) CRYSTAL STRUCTURE OF GDP-BOUND AIF5B FROM AEROPYRUM PERNIX | TRANSLATION INITIATON FACTOR, GTPASE, RIBOSOMAL SUBUNIT JOINING, CRENARCHAEA, TRANSLATION
3n9x:B (ARG61) to (PRO96) CRYSTAL STRUCTURE OF MAP KINASE FROM PLASMODIUM BERGHEI, PB000659.00.0 | MALARIA KINASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
3cai:A (ASP32) to (ALA85) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS RV3778C PROTEIN | RV3778C, AMINOTRANSFERASE, TRANSFERASE
4r9s:A (THR196) to (LYS233) MYCOBACTERIUM TUBERCULOSIS INHA BOUND TO NITD-916 | ENOYL ACYL CARRIER PROTEIN REDUCTASE, OXIDOREDUCTASE
4r9s:C (THR196) to (LYS233) MYCOBACTERIUM TUBERCULOSIS INHA BOUND TO NITD-916 | ENOYL ACYL CARRIER PROTEIN REDUCTASE, OXIDOREDUCTASE
4r9s:E (THR196) to (LYS233) MYCOBACTERIUM TUBERCULOSIS INHA BOUND TO NITD-916 | ENOYL ACYL CARRIER PROTEIN REDUCTASE, OXIDOREDUCTASE
4r9s:G (THR196) to (LYS233) MYCOBACTERIUM TUBERCULOSIS INHA BOUND TO NITD-916 | ENOYL ACYL CARRIER PROTEIN REDUCTASE, OXIDOREDUCTASE
4c30:A (SER593) to (THR625) CRYSTAL STRUCTURE OF DEINOCOCCUS RADIODURANS UVRD IN COMPLEX WITH DNA, FORM 2 | HYDROLASE-DNA COMPLEX, DNA REPAIR, DNA HELICASES, NUCLEOTIDE EXCISION REPAIR
4c30:I (SER593) to (ALA626) CRYSTAL STRUCTURE OF DEINOCOCCUS RADIODURANS UVRD IN COMPLEX WITH DNA, FORM 2 | HYDROLASE-DNA COMPLEX, DNA REPAIR, DNA HELICASES, NUCLEOTIDE EXCISION REPAIR
3ng3:A (VAL97) to (VAL128) CRYSTAL STRUCTURE OF DEOXYRIBOSE PHOSPHATE ALDOLASE FROM MYCOBACTERIUM AVIUM 104 IN A SCHIFF BASE WITH AN UNKNOWN ALDEHYDE | SSGCID, SBRI, UW, ALS DEOXYRIBOSEPHOSPHATE ALDOLASE, MYCOBACTERIUM AVIUM 104, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, LYASE
3ng3:D (VAL97) to (VAL128) CRYSTAL STRUCTURE OF DEOXYRIBOSE PHOSPHATE ALDOLASE FROM MYCOBACTERIUM AVIUM 104 IN A SCHIFF BASE WITH AN UNKNOWN ALDEHYDE | SSGCID, SBRI, UW, ALS DEOXYRIBOSEPHOSPHATE ALDOLASE, MYCOBACTERIUM AVIUM 104, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, LYASE
3ciz:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3ciz:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3cj3:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj3:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj4:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj4:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj5:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cja:A (ALA123) to (GLY156) STRUCTURE OF RATTUS NORVEGICUS NTPDASE2 IN COMPLEX WITH CALCIUM AND AMPPNP | HYDROLASE, ALPHA/BETA PROTEIN, ACTIN-LIKE FOLD, ALTERNATIVE SPLICING, CALCIUM, GLYCOPROTEIN, MAGNESIUM, MEMBRANE, TRANSMEMBRANE
5fnc:A (LYS191) to (GLU223) DYNAMIC UNDOCKING AND THE QUASI-BOUND STATE AS TOOLS FOR DRUG DESIGN | HSP90, DRUG DESIGN, CHAPERONE, ONCOLOGY
5fnf:A (LYS191) to (GLU223) DYNAMIC UNDOCKING AND THE QUASI-BOUND STATE AS TOOLS FOR DRUG DESIGN | HSP90, DRUG DESIGN, CHAPERONE, ONCOLOGY
5fpu:A (ASP630) to (ARG679) CRYSTAL STRUCTURE OF HUMAN JARID1B IN COMPLEX WITH GSKJ1 | TRANSCRIPTION, LYSINE-SPECIFIC DEMETHYLASE 5B
3nuh:B (THR616) to (PHE649) A DOMAIN INSERTION IN E. COLI GYRB ADOPTS A NOVEL FOLD THAT PLAYS A CRITICAL ROLE IN GYRASE FUNCTION | GYRASE, TOPOISOMERASE, SUPERCOILING, SPECIALIZATION, ISOMERASE
5fup:A (SER628) to (ARG679) CRYSTAL STRUCTURE OF HUMAN JARID1B IN COMPLEX WITH 2-OXOGLUTARATE. | OXIDOREDUCTASE, JARID1B, PLU1
3cqy:A (THR42) to (HIS97) CRYSTAL STRUCTURE OF A FUNCTIONALLY UNKNOWN PROTEIN (SO_1313) FROM SHEWANELLA ONEIDENSIS MR-1 | APC7501, SO_1313, STRUCTURAL GENOMICS, PSI-2, SHEWANELLA ONEIDENSIS MR-1, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, ATP-BINDING, CARBOHYDRATE METABOLISM, KINASE, NUCLEOTIDE-BINDING, TRANSFERASE
4ckt:A (ASN125) to (TYR167) PIH1 N-TERMINAL DOMAIN | CHAPERONE-PEPTIDE COMPLEX, CHAPERONE, MULTIPROTEIN COMPLEXES, PHOSPHORYLATION, R2TP
3o1n:B (PHE52) to (PHE81) 1.03 ANGSTROM CRYSTAL STRUCTURE OF Q236A MUTANT TYPE I DEHYDROQUINATE DEHYDRATASE (AROD) FROM SALMONELLA TYPHIMURIUM | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, TIM BARREL, DEHYDRATASE, LYASE
4clc:C (ASP5) to (THR33) CRYSTAL STRUCTURE OF YBR137W PROTEIN | PROTEIN TRANSPORT, GET, GET PATHWAY
4clc:D (ASP5) to (THR33) CRYSTAL STRUCTURE OF YBR137W PROTEIN | PROTEIN TRANSPORT, GET, GET PATHWAY
4clc:E (ASP5) to (THR33) CRYSTAL STRUCTURE OF YBR137W PROTEIN | PROTEIN TRANSPORT, GET, GET PATHWAY
3cwh:A (PRO97) to (THR133) D-XYLOSE ISOMERASE IN COMPLEX WITH LINEAR PRODUCT, PER-DEUTERATED XYLULOSE | ENZYME-PRODUCT COMPLEX, CARBOHYDRATE METABOLISM, ISOMERASE, MAGNESIUM, METAL-BINDING, PENTOSE SHUNT, XYLOSE METABOLISM
3cwj:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, HEPATITIS, TRANSFERASE, VIRAL PROTEIN
4ry4:A (GLY188) to (ARG222) C-TERMINAL MUTANT (Y448F) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4ry5:A (GLY188) to (THR221) C-TERMINAL MUTANT (W550N) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4ry7:A (GLY188) to (ARG222) C-TERMINAL MUTANT (D559E) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
5fyu:A (SER628) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH 3D FRAGMENT 3-AMINO-4-METHYL-1,3-DIHYDRO-2H-INDOL-2-ONE (N10042A) | OXIDOREDUCTASE, JARID1B, PLU1, PANDDA, FRAGMENT SOAKING, X-RAY FRAGMENT SCREENING, STRUCTURAL GENOMICS CONSORTIUM, SGC
5fyy:A (SER628) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH MAYBRIDGE FRAGMENT 3-PYRIDIN-3-YLANILINE (N05798A) (LIGAND MODELLED BASED ON PANDDA EVENT MAP) | OXIDOREDUCTASE, JARID1B, PLU1, PANDDA, FRAGMENT SOAKING, X-RAY FRAGMENT SCREENING
5fyz:A (SER628) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH 3D FRAGMENT 2-(2-OXO-2,3-DIHYDRO-1H-INDOL-3-YL)ACETONITRILE (N10063A) | OXIDOREDUCTASE, JARID1B, PLU1, PANDDA, FRAGMENT SOAKING, X-RAY FRAGMENT SCREENING, STRUCTURAL GENOMICS CONSORTIUM, SGC
5fz0:A (ASP630) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH 2,5-DICHLORO-N-(PYRIDIN-3-YL)THIOPHENE-3-CARBOXAMIDE (N08137B) (LIGAND MODELLED BASED ON PANDDA EVENT MAP, SGC - DIAMOND I04-1 FRAGMENT SCREENING) | OXIDOREUCTASE, JARID1B, PLU1, PANDDA, FRAGMENT SOAKING, X-RAY FRAGMENT SCREENING
5fz1:A (SER628) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX 2,4-DICHLORO-N-PYRIDIN-3-YLBENZAMIDE (E48115B) (LIGAND MODELLED BASED PANDDA EVENT MAP) | OXIDOREDUCTASE, JARID1B, PLU1, FRAGMENT SCREENING, STRUCTURAL GENOMICS CONSORTIUM, SGC, PANDDA
5fz3:A (ASP630) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH MAYBRIDGE FRAGMENT 3,6-DIHYDROXYBENZONORBORNANE (N08776B) (LIGAND MODELLED BASED ON PANDDA EVENT MAP) | OXIDOREDUCTASE, JARID1B, PLU1, FRAGMENT SCREENING, STRUCTURAL GENOMICS CONSORTIUM, SGC, DIAMOND I04-1, PANDDA
3o5b:B (PRO115) to (SER157) CRYSTAL STRUCTURE OF DIMERIC KLHXK1 IN CRYSTAL FORM VII WITH GLUCOSE BOUND (OPEN STATE) | RNASEH-LIKE FOLD, HEXOKINASE, GLYCOLYSIS, GLUCOSE REPRESSION, ATP BINDING, MIG1 BINDING, TRANSFERASE
5fz6:A (ASP630) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH MAYBRIDGE FRAGMENT N05859B (LIGAND MODELLED BASED ON PANDDA EVENT MAP, SGC - DIAMOND I04-1 FRAGMENT SCREENING) | OXIDOREDUCTASE, JARID1B, PLU1, FRAGMENT SCREENING, STRUCTURAL GENOMICS CONSORTIUM, SGC, DIAMOND I04-1, PANDDA
5fz7:A (SER628) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH MAYBRIDGE FRAGMENT ETHYL 2-AMINO-4- THIOPHEN-2-YLTHIOPHENE-3-CARBOXYLATE (N06131B) (LIGAND MODELLED BASED ON PANDDA EVENT MAP, SGC - DIAMOND I04-1 FRAGMENT SCREENING) | OXIDOREDUCTASE, JARID1B, PLU1, FRAGMENT SCREENING, STRUCTURAL GENOMICS CONSORTIUM, SGC, DIAMOND I04-1, PANDDA
5fzb:A (ASP630) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH MAYBRIDGE FRAGMENT 4-PYRIDYLTHIOUREA (N06275B) (LIGAND MODELLED BASED ON PANDDA EVENT MAP, SGC - DIAMOND I04-1 FRAGMENT SCREENING) | OXIDOREDUCTASE, JARID1B, PLU1, FRAGMENT SCREENING, STRUCTURAL GENOMICS CONSORTIUM, SGC, DIAMOND I04-1, PANDDA
5fzl:A (SER628) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH 3D FRAGMENT 3-METHYL-N-PYRIDIN-4-YL-1,2- OXAZOLE-5-CARBOXAMIDE (N09954A) (LIGAND MODELLED BASED ON PANDDA EVENT MAP, SGC - DIAMOND I04-1 FRAGMENT SCREENING) | OXIDOREDUCTASE, JARID1B, PLU1, FRAGMENT SCREENING, STRUCTURAL GENOMICS CONSORTIUM, SGC, DIAMOND I04-1, PANDDA
5fzc:A (ASP630) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH MAYBRIDGE FRAGMENT 4,5-DIHYDRONAPHTHO(1,2- B)THIOPHENE-2-CARBOXYLICACID (N11181A) (LIGAND MODELLED BASED ON PANDDA EVENT MAP, SGC - DIAMOND I04-1 FRAGMENT SCREENING) | OXIDOREDUCTASE, JARID1B, PLU1, FRAGMENT SCREENING, STRUCTURAL GENOMICS CONSORTIUM, SGC, DIAMOND I04-1, PANDDA
5fzk:A (SER628) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH 3D FRAGMENT N,3-DIMETHYL-N-(PYRIDIN-3- YLMETHYL)-1,2-OXAZOLE-5-CARBOXAMIDE (N10051A) (LIGAND MODELLED BASED ON PANDDA EVENT MAP, SGC - DIAMOND I04-1 FRAGMENT SCREENING) | OXIDOREDUCTASE, JARID1B, PLU1, FRAGMENT SCREENING, STRUCTURAL GENOMICS CONSORTIUM, SGC, DIAMOND I04-1, PANDDA
3d28:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL BENZISOTHIAZOLE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEOTIDE-BINDING, TRANSCRIPTION, HYDROLASE, TRANSFERASE
5g0s:B (ALA198) to (LYS233) INHA IN COMPLEX WITH A DNA ENCODED LIBRARY HIT | OXIDOREDUCTASE, INHA, ACP ENOYL REDUCTASE, DNA ENCODED LIBRARY, DEL, TUBERCULOSIS
5g0s:D (ALA198) to (LYS233) INHA IN COMPLEX WITH A DNA ENCODED LIBRARY HIT | OXIDOREDUCTASE, INHA, ACP ENOYL REDUCTASE, DNA ENCODED LIBRARY, DEL, TUBERCULOSIS
5g0u:A (ALA198) to (LYS233) INHA IN COMPLEX WITH A DNA ENCODED LIBRARY HIT | OXIDOREDUCTASE, INHA, ACP ENOYL REDUCTASE, DNA ENCODED LIBRARY, DEL, TUBERCULOSIS
5g0u:B (ALA198) to (LYS233) INHA IN COMPLEX WITH A DNA ENCODED LIBRARY HIT | OXIDOREDUCTASE, INHA, ACP ENOYL REDUCTASE, DNA ENCODED LIBRARY, DEL, TUBERCULOSIS
5g0u:D (ALA198) to (LYS233) INHA IN COMPLEX WITH A DNA ENCODED LIBRARY HIT | OXIDOREDUCTASE, INHA, ACP ENOYL REDUCTASE, DNA ENCODED LIBRARY, DEL, TUBERCULOSIS
5g0v:D (THR196) to (LYS233) INHA IN COMPLEX WITH A DNA ENCODED LIBRARY HIT | OXIDOREDUCTASE, INHA, ACP ENOYL REDUCTASE, DNA ENCODED LIBRARY, DEL, TUBERCULOSIS
3d4u:A (VAL113) to (TYR198) BOVINE THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR (TAFIA) IN COMPLEX WITH TICK-DERIVED CARBOXYPEPTIDASE INHIBITOR. | PROTEASE-INHIBITOR COMPLEX, CARBOXYPEPTIDASE, GLYCOPROTEIN, HYDROLASE, METAL-BINDING, METALLOPROTEASE, PROTEASE, SECRETED, ZYMOGEN, BLOOD COAGULATION, FIBRINOLYSIS, METALLOENZYME INHIBITOR, METALLOPROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4cse:A (ASN125) to (TYR167) PIH N-TERMINAL DOMAIN | CHAPERONE, MOLECULAR CHAPERONES, MULTIPROTEIN COMPLEXES, PHOSPHORYLATION
4cse:B (ASN125) to (LEU165) PIH N-TERMINAL DOMAIN | CHAPERONE, MOLECULAR CHAPERONES, MULTIPROTEIN COMPLEXES, PHOSPHORYLATION
3d5m:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA POLYMERASE, RNA REPLICATION, RNA-BINDING, TRANSCRIPTION, NUCLEOTIDYLTRANSFERASE, HYDROLASE
3d5m:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA POLYMERASE, RNA REPLICATION, RNA-BINDING, TRANSCRIPTION, NUCLEOTIDYLTRANSFERASE, HYDROLASE
4ct8:A (LEU311) to (THR339) COMPETENCE OR DAMAGE-INDUCIBLE PROTEIN CINA FROM THERMUS THERMOPHILUS | BIOSYNTHETIC PROTEIN, COMPETENCE, DAMAGE, NAD RECYCLING
4ct8:B (LEU311) to (THR339) COMPETENCE OR DAMAGE-INDUCIBLE PROTEIN CINA FROM THERMUS THERMOPHILUS | BIOSYNTHETIC PROTEIN, COMPETENCE, DAMAGE, NAD RECYCLING
4ct9:A (LEU311) to (THR339) COMPETENCE OR DAMAGE-INDUCIBLE PROTEIN CINA FROM THERMUS THERMOPHILUS | BIOSYNTHETIC PROTEIN, COMPETENCE, DAMAGE, NAD RECYCLING
4cta:A (LEU311) to (THR339) COMPETENCE OR DAMAGE-INDUCIBLE PROTEIN CINA FROM THERMUS THERMOPHILUS | BIOSYNTHETIC PROTEIN, COMPETENCE, DAMAGE, NAD RECYCLING
4cta:B (LEU311) to (THR339) COMPETENCE OR DAMAGE-INDUCIBLE PROTEIN CINA FROM THERMUS THERMOPHILUS | BIOSYNTHETIC PROTEIN, COMPETENCE, DAMAGE, NAD RECYCLING
3d67:A (VAL203) to (MET287) CRYSTAL STRUCTURE OF THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR (TAFI) IN COMPLEX WITH 2-GUANIDINO-ETHYL-MERCAPTOSUCCINIC ACID (GEMSA) | PROTEIN-INHIBITOR COMPLEX, ALPHA/BETA HYDROLASE FOLD, CARBOXYPEPTIDASE, GLYCOPROTEIN, METAL-BINDING, METALLOPROTEASE, PROTEASE, SECRETED, ZYMOGEN, HYDROLASE
4tlr:A (GLY188) to (ARG222) NS5B IN COMPLEX WITH LACTAM-THIOPHENE CARBOXYLIC ACIDS | COMPLEX POLYMERASE INHBITOR
3obe:B (GLY56) to (ASP86) CRYSTAL STRUCTURE OF A SUGAR PHOSPHATE ISOMERASE/EPIMERASE (BDI_3400) FROM PARABACTEROIDES DISTASONIS ATCC 8503 AT 1.70 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, ISOMERASE
4tma:B (GLU617) to (PHE649) CRYSTAL STRUCTURE OF GYRASE BOUND TO ITS INHIBITOR YACG | ISOMERASE, DUF329, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
4tmv:B (PHE664) to (LEU699) TRANSLATION INITIATION FACTOR EIF5B (517-858) FROM C. THERMOPHILUM, BOUND TO GTPGAMMAS AND SODIUM | RIBOSOME, TRANSLATION, INITIATION FACTOR, GTPASE
4tn2:A (GLY188) to (ARG222) NS5B IN COMPLEX WITH LACTAM-THIOPHENE CARBOXYLIC ACIDS | COMPLEX POLYMERASE INHBITOR, HYDROLASE
4cwp:A (LYS191) to (GLU223) HUMAN HSP90 ALPHA N-TERMINAL DOMAIN IN COMPLEX WITH AN AMINOTRIAZOLOQUINAZOLINE INHIBITOR | CHAPERONE
4cws:A (LYS191) to (GLU223) HUMAN HSP90 ALPHA N-TERMINAL DOMAIN IN COMPLEX WITH AN AMINOTRIAZOLOQUINAZOLINE INHIBITOR | CHAPERONE
4d0r:A (LEU197) to (LYS233) MTB INHA COMPLEX WITH PYRADIZINONE COMPOUND 1 | OXIDOREDUCTASE, ACP ENOYL REDUCTASE, METHYL-THIAZOLE
4ttr:A (ARG73) to (GLU117) CRYSTAL STRUCTURE OF LEGIONELLA PNEUMOPHILA DEPHOSPHO-COA KINASE IN COMPLEX WITH BU2 | KINASE, P-LOOP, COENZYME METABOLISM, TRANSFERASE
3dlg:B (ARG358) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW564511. | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NNRTI, GW564511, DRUG RESISTANCE, TRANSFERASE, HYDROLASE
3dm2:B (ARG358) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 K103N MUTANT REVERSE TRANSCRIPTASE IN COMPLEX WITH GW564511. | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NNRTI, GW564511, DRUG RESISTANCE, K103N MUTATION, HYDROLASE, TRANSFERASE
3dmj:B (ARG358) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 V106A AND Y181C MUTANT REVERSE TRANSCRIPTASE IN COMPLEX WITH GW564511. | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NNRTI, GW564511, DRUG RESISTANCE, HYDROLASE, TRANSFERASE
4ty8:D (GLY188) to (ARG222) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3opd:B (LYS176) to (GLU208) CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF AN HSP90 FROM TRYPANOSOMA BRUCEI, TB10.26.1080 IN THE PRESENCE OF A BENZAMIDE DERIVATIVE | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, CHAPERONE, ATP BINDING
4u2m:A (LYS170) to (ASP198) CRYSTAL STRUCTURE OF A COMPLEX OF THE MIZ1- AND BCL6 POZ DOMAINS. | POZ DOMAIN, BTB DOMAIN, TRANSCRIPTION
3osl:A (VAL225) to (TYR312) STRUCTURE OF BOVINE THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR IN COMPLEX WITH TICK CARBOXYPEPTIDASE INHIBITOR | ALPHA/BETA-HYDROLASE-RELATED FOLD, BLOOD, FIBRINOLYSIS, COAGULATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3osl:C (VAL225) to (TYR312) STRUCTURE OF BOVINE THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR IN COMPLEX WITH TICK CARBOXYPEPTIDASE INHIBITOR | ALPHA/BETA-HYDROLASE-RELATED FOLD, BLOOD, FIBRINOLYSIS, COAGULATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3dw8:C (THR7) to (ARG49) STRUCTURE OF A PROTEIN PHOSPHATASE 2A HOLOENZYME WITH B55 SUBUNIT | HOLOENZYME, B55, PR55, WD REPEAT, HYDROLASE, IRON, MANGANESE, METAL- BINDING, METHYLATION, PHOSPHOPROTEIN, PROTEIN PHOSPHATASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hex:B (PRO563) to (PHE604) CRYSTAL STRUCTURE OF HUMAN HEXOKINASE 2 WITH CMPD 30, A 2-AMINO-6- BENZENESULFONAMIDE GLUCOSAMINE | INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4die:B (GLY87) to (GLY125) CRYSTAL STRUCTURE OF A CYTIDYLATE KINASE CMK FROM MYCOBACTERIUM ABSCESSUS BOUND TO CYTIDINE-5'-MONOPHOSPHATE | STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, KINASE, MYCOBACTERIUM, CYTIDINE MONOPHOSPHATE KINASE, CK, TRANSFERASE
4die:D (GLY87) to (GLY125) CRYSTAL STRUCTURE OF A CYTIDYLATE KINASE CMK FROM MYCOBACTERIUM ABSCESSUS BOUND TO CYTIDINE-5'-MONOPHOSPHATE | STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, KINASE, MYCOBACTERIUM, CYTIDINE MONOPHOSPHATE KINASE, CK, TRANSFERASE
4dl0:J (THR9) to (LYS140) CRYSTAL STRUCTURE OF THE HETEROTRIMERIC EGCHEAD PERIPHERAL STALK COMPLEX OF THE YEAST VACUOLAR ATPASE | COILED-COIL, HETEROTRIMER, PERIPHERAL STALK, STATOR COMPLEX, HYDROLASE, ION TRANSPORT, VACUOLAR ATPASE, VACUOLAR MEMBRANE
4dl0:E (THR9) to (LYS140) CRYSTAL STRUCTURE OF THE HETEROTRIMERIC EGCHEAD PERIPHERAL STALK COMPLEX OF THE YEAST VACUOLAR ATPASE | COILED-COIL, HETEROTRIMER, PERIPHERAL STALK, STATOR COMPLEX, HYDROLASE, ION TRANSPORT, VACUOLAR ATPASE, VACUOLAR MEMBRANE
3p4i:A (ASP272) to (THR318) CRYSTAL STRUCTURE OF ACETATE KINASE FROM MYCOBACTERIUM AVIUM | STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, MYCOBACTERIUM, TUBERCULOSIS, NON- PATHOGENIC SPECIES, ORTHOLOG, PYRUVATE, PROPANOATE, ACETYL-COA BIOSYNTHESIS, KINASE, TRANSFERASE
4dmv:A (GLN248) to (ASP285) CRYSTAL STRUCTURE OF THE GT DOMAIN OF CLOSTRIDIUM DIFFICILE TOXIN A | TRANSFERASE
3p71:C (ASP2) to (ARG49) CRYSTAL STRUCTURE OF THE COMPLEX OF LCMT-1 AND PP2A | LEUCINE CARBOXYMETHYLTRANSFERASE-1,SERINE/THREONINE PROTEIN KEYWDS 2 PHOSPHATASE 2A, METHYLTRANSFERASE, S-ADENOSYL-L-METHIONINE, TRANSFERASE-HYDROLASE COMPLEX
5hvh:A (PRO297) to (GLY334) CRYSTAL STRUCTURE OF THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR IN COMPLEX WITH TWO INHIBITORY NANOBODIES | PROCARBOXYPEPTIDASE U, THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR, TAFI, PROCARBOXYPEPTIDASE R, PLASMA PROCARBOXYPEPTIDASE B, NANOBODY, ANTIBODY FRAGMENT, PROTEIN COMPLEX, HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3e51:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEOTIDE-BINDING, TRANSCRIPTION, TRANSFERASE
3e51:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEOTIDE-BINDING, TRANSCRIPTION, TRANSFERASE
3peh:B (LYS248) to (LEU278) CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF AN HSP90 FROM PLASMODIUM FALCIPARUM, PFL1070C IN THE PRESENCE OF A THIENOPYRIMIDINE DERIVATIVE | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, HEAT SHOCK PROTEIN, CHAPERONE, ATP BINDING
3phe:C (GLY188) to (ARG222) HCV NS5B WITH A BOUND QUINOLONE INHIBITOR | TRANSFERASE, POLYMERASE, RNA, MITOCHONDRIAL MEMBRANE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4uoc:A (LEU311) to (THR339) COMPETENCE OR DAMAGE-INDUCIBLE PROTEIN CINA FROM THERMUS THERMOPHILUS | UNKNOWN FUNCTION, COMPETENCE, DAMAGE, NAD RECYCLING
4uoc:B (LEU311) to (THR339) COMPETENCE OR DAMAGE-INDUCIBLE PROTEIN CINA FROM THERMUS THERMOPHILUS | UNKNOWN FUNCTION, COMPETENCE, DAMAGE, NAD RECYCLING
4e22:A (GLU94) to (GLY130) STRUCTURE OF CYTIDINE MONOPHOSPHATE KINASE FROM YERSINIA PSEUDOTUBERCULOSIS | P-LOOP, CMP/ATP BINDING, TRANSFERASE
4uuw:A (LEU311) to (THR339) COMPETENCE OR DAMAGE-INDUCIBLE PROTEIN CINA FROM THERMUS THERMOPHILUS | BIOSYNTHETIC PROTEIN, COMPETENCE, DAMAGE, NAD RECYCLING
4uux:A (LEU311) to (THR339) COMPETENCE OR DAMAGE-INDUCIBLE PROTEIN CINA FROM THERMUS THERMOPHILUS | BIOSYNTHETIC PROTEIN, COMPETENCE, DAMAGE, NAD RECYCLING
4uux:B (LEU311) to (THR339) COMPETENCE OR DAMAGE-INDUCIBLE PROTEIN CINA FROM THERMUS THERMOPHILUS | BIOSYNTHETIC PROTEIN, COMPETENCE, DAMAGE, NAD RECYCLING
4uvi:D (THR196) to (LYS233) DISCOVERY OF PYRIMIDINE ISOXAZOLES INHA IN COMPLEX WITH COMPOUND 23 | OXIDOREDUCTASE, INHA, ACP ENOYL REDUCTASE, FBLG, PYRIMIDINE ISOXAZOLE
4eaw:B (GLY188) to (ARG222) HCV NS5B IN COMPLEX WITH IDX375 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3q0z:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3q0z:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eo6:A (GLY188) to (ARG222) HCV NS5B POLYMERASE INHIBITORS: TRI-SUBSTITUTED ACYLHYDRAZINES AS TERTIARY AMIDE BIOISOSTERES | HCV, NS5B, RNA, RNA POLYMERASE, POLYMERASE INHIBITOR, THUMB SITE 2 INHIBITOR, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eo6:B (GLY188) to (ARG222) HCV NS5B POLYMERASE INHIBITORS: TRI-SUBSTITUTED ACYLHYDRAZINES AS TERTIARY AMIDE BIOISOSTERES | HCV, NS5B, RNA, RNA POLYMERASE, POLYMERASE INHIBITOR, THUMB SITE 2 INHIBITOR, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3q5l:C (LYS176) to (GLU208) CRYSTAL STRUCTURE OF THE AMINO-TERMINAL DOMAIN OF HSP90 FROM LEISHMANIA MAJOR, LMJF33.0312:M1-K 213 IN THE PRESENCE OF 17-AEP- GELDANAMYCIN | SLEEPING SICKNESS, LEISHMANIA, HEAT SHOCK PROTEIN, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, CHAPERONE
3q5l:D (LYS176) to (GLU208) CRYSTAL STRUCTURE OF THE AMINO-TERMINAL DOMAIN OF HSP90 FROM LEISHMANIA MAJOR, LMJF33.0312:M1-K 213 IN THE PRESENCE OF 17-AEP- GELDANAMYCIN | SLEEPING SICKNESS, LEISHMANIA, HEAT SHOCK PROTEIN, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, CHAPERONE
3qbw:A (ALA39) to (HIS94) CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA 1,6-ANHYDRO-N- ACTETYLMURAMIC ACID KINASE (ANMK) BOUND TO ADENOSINE DIPHOSPHATE | ACETATE AND SUGAR KINASES, HSP70, ACTIN SUPERFAMILY, KINASE, 1,6- ANHYDRO-N-ACTETYLMURAMIC ACID BINDING, GLYCOSIDE HYDROLASE, ATP- BINDING, CARBOHYDRATE METABOLISM, PEPTIDOGLYCAN RECYCLING, TRANSFERASE
3qbx:A (ALA39) to (HIS94) CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA 1,6-ANHYDRO-N- ACTETYLMURAMIC ACID KINASE (ANMK) BOUND TO 1,6-ANHYDRO-N- ACTETYLMURAMIC ACID | ACETATE AND SUGAR KINASES, HSP70, ACTIN SUPERFAMILY, KINASE, 1,6- ANHYDRO-N-ACTETYLMURAMIC ACID BINDING, GLYCOSIDE HYDROLASE, ATP- BINDING, CARBOHYDRATE METABOLISM, PEPTIDOGLYCAN RECYCLING, TRANSFERASE
3qbx:B (ALA39) to (HIS94) CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA 1,6-ANHYDRO-N- ACTETYLMURAMIC ACID KINASE (ANMK) BOUND TO 1,6-ANHYDRO-N- ACTETYLMURAMIC ACID | ACETATE AND SUGAR KINASES, HSP70, ACTIN SUPERFAMILY, KINASE, 1,6- ANHYDRO-N-ACTETYLMURAMIC ACID BINDING, GLYCOSIDE HYDROLASE, ATP- BINDING, CARBOHYDRATE METABOLISM, PEPTIDOGLYCAN RECYCLING, TRANSFERASE
3qgd:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-1-[(4-ETHYLPHENYL)SULFONYL]- N-(4-METHOXYBENZYL)PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qgd:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-1-[(4-ETHYLPHENYL)SULFONYL]- N-(4-METHOXYBENZYL)PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qge:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qge:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qgf:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(6-CHLOROPYRIDAZIN-3-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qgf:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(6-CHLOROPYRIDAZIN-3-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5j8l:A (ASP74) to (LEU108) CRYSTAL STRUCTURE OF D-TAGATOSE 3-EPIMERASE C66S FROM PSEUDOMONAS CICHORII IN COMPLEX WITH 1-DEOXY L-TAGATOSE, USING A CRYSTAL GROWN IN MICROGRAVITY | EPIMERASE, ISOMERASE
4f9d:A (SER492) to (LEU542) STRUCTURE OF ESCHERICHIA COLI PGAB 42-655 IN COMPLEX WITH NICKEL | FAMILY 4 CARBOHYDRATE ESTERASE, TIM BARREL, HYDROLASE, DEACETYLASE, CARBOHYDRATE/SUGAR BINDING
4f9d:B (LEU493) to (LEU542) STRUCTURE OF ESCHERICHIA COLI PGAB 42-655 IN COMPLEX WITH NICKEL | FAMILY 4 CARBOHYDRATE ESTERASE, TIM BARREL, HYDROLASE, DEACETYLASE, CARBOHYDRATE/SUGAR BINDING
4f9j:A (LEU493) to (LEU542) STRUCTURE OF ESCHERICHIA COLI PGAB 42-655 IN COMPLEX WITH IRON | FAMILY 4 CARBOHYDRATE ESTERASE, TIM BARREL, CARBOHYDRATE/SUGAR BINDING, HYDROLASE, DEACETYLASE
4f9j:B (LEU493) to (LEU542) STRUCTURE OF ESCHERICHIA COLI PGAB 42-655 IN COMPLEX WITH IRON | FAMILY 4 CARBOHYDRATE ESTERASE, TIM BARREL, CARBOHYDRATE/SUGAR BINDING, HYDROLASE, DEACETYLASE
3qr9:A (ARG187) to (ALA222) ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE (TRPD) FROM MYCOBACTERIUM TUBERCULOSIS (APO STRUCTURE) | ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE, ANTHRANILIC ACIDS, MAGNESIUM, TRYPTOPHAN, MAGNESIUM BINDING, PHOSPHORIBOSYL PYROPHOSPHATE, TRANSFERASE, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC
3qxb:A (SER120) to (VAL161) CRYSTAL STRUCTURE OF A PUTATIVE XYLOSE ISOMERASE (YP_426450.1) FROM RHODOSPIRILLUM RUBRUM ATCC 11170 AT 1.90 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, ISOMERASE
3qxb:C (SER120) to (VAL161) CRYSTAL STRUCTURE OF A PUTATIVE XYLOSE ISOMERASE (YP_426450.1) FROM RHODOSPIRILLUM RUBRUM ATCC 11170 AT 1.90 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, ISOMERASE
3r8c:A (ALA93) to (GLY125) CRYSTAL STRUCTURE OF CYTIDYLATE KINASE (CMK) FROM MYCOBACTERIUM ABSCESSUS | STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, MYCOBACTERIUM, TUBERCULOSIS, WATER CONTAMINANT, CHRONIC LUNG DISEASE, RAPID GROWING MYCOBACTERIUM, PYRIMIDINE NUCLEOSIDE MONOPHOSPHATE KINASE, PHOSPHOTRANSFERASE,, TRANSFERASE
3r8c:B (ASN88) to (GLY125) CRYSTAL STRUCTURE OF CYTIDYLATE KINASE (CMK) FROM MYCOBACTERIUM ABSCESSUS | STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, MYCOBACTERIUM, TUBERCULOSIS, WATER CONTAMINANT, CHRONIC LUNG DISEASE, RAPID GROWING MYCOBACTERIUM, PYRIMIDINE NUCLEOSIDE MONOPHOSPHATE KINASE, PHOSPHOTRANSFERASE,, TRANSFERASE
3r9p:A (ASP271) to (THR317) CRYSTAL STRUCTURE OF ACKA FROM MYCOBACTERIUM PARATUBERCULOSIS ATCC BAA-968 / K-10 | SSGCID, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, ACETATE KINASE, TRANSFERASE
3ras:A (GLY206) to (VAL241) CRYSTAL STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE (DXR) COMPLEXED WITH A LIPOPHILIC PHOSPHONATE INHIBITOR | OXIDOREDUCTASE, DOXP/MEP PATHWAY, ISOPRENE BIOSYNTHESIS, 1-DEOXY-D- XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5jfo:A (LEU197) to (LYS233) STRUCTURE OF THE M.TUBERCULOSIS ENOYL-REDUCTASE INHA IN COMPLEX WITH GSK625 | ANTITUBERCULAR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5jfo:B (LEU197) to (LYS233) STRUCTURE OF THE M.TUBERCULOSIS ENOYL-REDUCTASE INHA IN COMPLEX WITH GSK625 | ANTITUBERCULAR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5jfo:C (LEU197) to (LYS233) STRUCTURE OF THE M.TUBERCULOSIS ENOYL-REDUCTASE INHA IN COMPLEX WITH GSK625 | ANTITUBERCULAR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5jfo:D (THR196) to (LYS233) STRUCTURE OF THE M.TUBERCULOSIS ENOYL-REDUCTASE INHA IN COMPLEX WITH GSK625 | ANTITUBERCULAR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5jpe:A (ILE173) to (ALA221) YEAST-SPECIFIC SERINE/THREONINE PROTEIN PHOSPHATASE (PPZ1) OF CANDIDA ALBICANS | YEAST SERINE/THREONINE PROTEIN PHOSPHATASE, HYDROLASE
5jpe:B (ILE173) to (ALA221) YEAST-SPECIFIC SERINE/THREONINE PROTEIN PHOSPHATASE (PPZ1) OF CANDIDA ALBICANS | YEAST SERINE/THREONINE PROTEIN PHOSPHATASE, HYDROLASE
4fwm:A (LEU279) to (THR324) CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM PROPIONATE KINASE (TDCD) IN COMPLEX WITH ATP | TRANSFERASE, KINASE, ACETATE AND SUGAR KINASES/HSC70/ACTIN (ASKHA) SUPERFAMILY, PROPIONATE KINASE, TDCD, SHORT-CHAIN FATTY ACID
4fws:A (LEU279) to (THR324) CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM PROPIONATE KINASE (TDCD) IN COMPLEX WITH CTP | TRANSFERASE, KINASE, ACETATE AND SUGAR KINASES/HSC70/ACTIN (ASKHA) SUPERFAMILY, TDCD, CTP, SHORT-CHAIN FATTY ACID
5jyb:A (SER58) to (ILE88) CRYSTAL STRUCTURE OF 3 MUTANT OF BA3275 (S116A, E243A, H313A), THE MEMBER OF S66 FAMILY OF SERINE PEPTIDASES | SERINE PEPTIDASE, HYDROLASE, INACTIVE ENZYME, BA3275, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
5jyb:B (SER58) to (ILE88) CRYSTAL STRUCTURE OF 3 MUTANT OF BA3275 (S116A, E243A, H313A), THE MEMBER OF S66 FAMILY OF SERINE PEPTIDASES | SERINE PEPTIDASE, HYDROLASE, INACTIVE ENZYME, BA3275, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
4gbm:A (THR136) to (HIS162) SULFOTRANSFERASE DOMAIN FROM THE CURACIN BIOSYNTHETIC PATHWAY | SULFOTRANSFERASE, POLYKETIDE SYNTHASE, CURACIN, PAP, PAPS, TRANSFERASE
4gqt:B (LYS179) to (VAL210) N-TERMINAL DOMAIN OF C. ELEGANS HSP90 | STRUCTURAL GENOMICS, APC102132, HSP90, CHAPERONE, ADP, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG
5lwb:A (SER628) to (ARG679) CRYSTAL STRUCTURE OF HUMAN JARID1B IN COMPLEX WITH S40650A | LYSINE-SPECIFIC DEMETHYLASE 5B, OXIDOREDUCTASE
5tfr:B (THR7) to (VAL35) CRYSTAL STRUCTURE OF ZIKA VIRUS NS5 PROTEIN | MTASE, METHYLTRANSFERASE, POLYMERASE, RDRP, RNA-DEPENDENT RNA POLYMERASE, FLAVIVIRUS, ZIKA, VIRAL PROTEIN
5trh:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-[(BENZENECARBONYL)AMINO]-3-[(4- CHLOROPHENYL)METHOXY]BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trh:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-[(BENZENECARBONYL)AMINO]-3-[(4- CHLOROPHENYL)METHOXY]BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trk:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA- DEPENDENT RNA POLYMERASE IN COMPLEX WITH N-{3-[(BENZENECARBONYL)AMINO]-4-[(4- CHLOROPHENYL)METHOXY]BENZENE-1-CARBONYL}GLYCINE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trk:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA- DEPENDENT RNA POLYMERASE IN COMPLEX WITH N-{3-[(BENZENECARBONYL)AMINO]-4-[(4- CHLOROPHENYL)METHOXY]BENZENE-1-CARBONYL}GLYCINE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5tsc:B (THR173) to (ALA229) THE CRYSTAL STRUCTURE OF LPG2147 FROM LEGIONELLA PNEUMOPHILA | MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, PSI-BIOLOGY, UNKNOWN FUNCTION
5tvg:A (THR70) to (ASP132) CRYSTAL STRUCTURE OF AN ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE (UDP- FORMING) FROM BURKHOLDERIA VIETNAMIENSIS | STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, TRANSFERASE
5tvg:C (THR70) to (ASP132) CRYSTAL STRUCTURE OF AN ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE (UDP- FORMING) FROM BURKHOLDERIA VIETNAMIENSIS | STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, TRANSFERASE
5xia:B (PRO96) to (GLY137) STRUCTURES OF D-XYLOSE ISOMERASE FROM ARTHROBACTER STRAIN B3728 CONTAINING THE INHIBITORS XYLITOL AND D-SORBITOL AT 2.5 ANGSTROMS AND 2.3 ANGSTROMS RESOLUTION, RESPECTIVELY | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
5xim:D (PRO97) to (GLY138) PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE- DIRECTED MUTAGENESIS OF METAL BINDING SITES | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTSE)
2ako:D (THR97) to (GLU128) CRYSTAL STRUCTURE OF GLUTAMATE 5-KINASE FROM CAMPYLOBACTER JEJUNI | STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, TRANSFERASE
1ah8:A (LYS178) to (THR210) STRUCTURE OF THE ORTHORHOMBIC FORM OF THE N-TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE | CHAPERONE, ATP-BINDING, HEAT SHOCK
1ah8:B (LYS178) to (THR210) STRUCTURE OF THE ORTHORHOMBIC FORM OF THE N-TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE | CHAPERONE, ATP-BINDING, HEAT SHOCK
1aky:A (GLY90) to (LYS114) HIGH-RESOLUTION STRUCTURES OF ADENYLATE KINASE FROM YEAST LIGATED WITH INHIBITOR AP5A, SHOWING THE PATHWAY OF PHOSPHORYL TRANSFER | ATP:AMP PHOSPHOTRANSFERASE, MYOKINASE, TRANSFERASE (PHOSPHOTRANSFERASE)
2opl:A (VAL12) to (GLY41) CRYSTAL STRUCTURE OF AN OSMC-LIKE PROTEIN (GSU2788) FROM GEOBACTER SULFURREDUCENS AT 1.50 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
2opl:B (VAL12) to (GLY41) CRYSTAL STRUCTURE OF AN OSMC-LIKE PROTEIN (GSU2788) FROM GEOBACTER SULFURREDUCENS AT 1.50 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNKNOWN FUNCTION
2ori:B (GLY85) to (TYR109) CRYSTAL STRUCTURE OF A THERMOSTABLE MUTANT OF BACILLUS SUBTILIS ADENYLATE KINASE (A193V/Q199R/) | THERMOSTABILITY, ADENYLATE KINASE, EXPERIMENTAL ADAPTIVE EVOLUTION, DIRECTED EVOLUTION, TRANSFERASE
1nsa:A (ILE113) to (ILE195) THREE-DIMENSIONAL STRUCTURE OF PORCINE PROCARBOXYPEPTIDASE B: A STRUCTURAL BASIS OF ITS INACTIVITY | PORCINE PROCARBOXYPEPTIDASE, SERINE PROTEASE
3en1:B (PRO20) to (PRO58) CRYSTAL STRUCTURE OF TOLUENE 2,3-DIOXYGENASE | IRON-SULFUR CLUSTER, MONONUCLEAR IRON, 2FE-2S, AROMATIC HYDROCARBONS CATABOLISM, DIOXYGENASE, IRON, IRON-SULFUR, METAL-BINDING, NAD, OXIDOREDUCTASE
3ewy:A (SER226) to (ALA258) K314A MUTANT OF HUMAN OROTIDYL-5'-MONOPHOSPHATE DECARBOXYLASE SOAKED WITH OMP, DECARBOXYLATED TO UMP | DECARBOXYLASE, TIM BARREL, UNUSUAL CATALYSIS, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
4x5d:A (ARG187) to (ALA222) ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE VARIANT R193A FROM MYCOBACTERIUM TUBERCULOSIS WITH ANTHRANILATE BOUND | ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE, ANTHRANILIC ACIDS, MYCOBACTERIUM TUBERCULOSIS, MAGNESIUM, TRYPTOPHAN, MUTATION, TRANSFERASE, MAGNESIUM BINDING, PHOSPHORIBOSYL PYROPHOSPHATE
2brk:A (GLY188) to (THR221) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH AN ALLOSTERIC INHIBITOR (COMPOUND 1) | TRANSFERASE, HEPATITIS C VIRUS, HCV, NS5B, POLYMERASE, RNA-DEPENDENT RNA- POLYMERASE, ALLOSTERIC INHIBITOR, ATP-BINDING
2brl:A (GLY188) to (THR221) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH AN ALLOSTERIC INHIBITOR (COMPOUND 2) | TRANSFERASE, HEPATITIS C VIRUS, HCV, NS5B, POLYMERASE, RNA-DEPENDENT RNA- POLYMERASE, ALLOSTERIC INHIBITOR, NUCLEOTIDYLTRANSFERASE
4x7v:A (ILE215) to (ASP244) MYCF MYCINAMICIN III 3'-O-METHYLTRANSFERASE (E35Q, E139A VARIANT) IN COMPLEX WITH MG, SAH AND MYCINAMICIN IV (PRODUCT) | MACROLIDE, METHYLTRANSFERASE, ANTIBIOTIC, NATURAL PRODUCT, TRANSFERASE-ANTIBIOTIC COMPLEX
4x7v:B (ILE215) to (ASP244) MYCF MYCINAMICIN III 3'-O-METHYLTRANSFERASE (E35Q, E139A VARIANT) IN COMPLEX WITH MG, SAH AND MYCINAMICIN IV (PRODUCT) | MACROLIDE, METHYLTRANSFERASE, ANTIBIOTIC, NATURAL PRODUCT, TRANSFERASE-ANTIBIOTIC COMPLEX
1c0t:B (ARG358) to (LYS390) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH BM+21.1326 | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NON-NUCLEOSIDE INHIBITOR, DRUG DESIGN, TRANSFERASE
4xcj:A (LYS181) to (GLU215) N-TERMINAL DOMAIN OF HSP90 FROM DICTYOSTELIUM DISCOIDEUM IN COMPLEX WITH ADP | HSP90, ADP, CHAPERONE
1c3q:A (GLY240) to (VAL269) CRYSTAL STRUCTURE OF NATIVE THIAZOLE KINASE IN THE MONOCLINIC FORM | ALPHA-BETA, ATP BINDING, KINASE, TRANSFERASE
1c3q:B (PRO241) to (VAL269) CRYSTAL STRUCTURE OF NATIVE THIAZOLE KINASE IN THE MONOCLINIC FORM | ALPHA-BETA, ATP BINDING, KINASE, TRANSFERASE
3seq:B (ILE60) to (GLY94) CRYSTAL STRUCTURE OF C176A MUTANT OF GLUTAMINE-DEPENDENT NAD+ SYNTHETASE FROM M. TUBERCULOSIS IN COMPLEX WITH AMPCPP AND NAAD+ | GLUTAMINE-AMIDOTRANSFERASE, GLUTAMINASE, GLUTAMINE-DEPENDENT NAD+ SYNTHETASE, LIGASE, AMMONIA TUNNELING, ATP BINDING, NAD, NUCLEOTIDE BINDING
3seq:C (ILE60) to (GLY94) CRYSTAL STRUCTURE OF C176A MUTANT OF GLUTAMINE-DEPENDENT NAD+ SYNTHETASE FROM M. TUBERCULOSIS IN COMPLEX WITH AMPCPP AND NAAD+ | GLUTAMINE-AMIDOTRANSFERASE, GLUTAMINASE, GLUTAMINE-DEPENDENT NAD+ SYNTHETASE, LIGASE, AMMONIA TUNNELING, ATP BINDING, NAD, NUCLEOTIDE BINDING
4i1u:A (ARG66) to (VAL110) APO CRYSTAL STRUCTURE OF A DEPHOSPHO-COA KINASE FROM BURKHOLDERIA VIETNAMIENSIS | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, NATIONAL INSTITUTE FOR ALLERGY AND INFECTIOUS DISEASE, COENZYME A, BIOSYNTHESIS, KINASE, ATP-DEPENDENT, TRANSFERASE
4i1u:B (ARG66) to (VAL110) APO CRYSTAL STRUCTURE OF A DEPHOSPHO-COA KINASE FROM BURKHOLDERIA VIETNAMIENSIS | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, NATIONAL INSTITUTE FOR ALLERGY AND INFECTIOUS DISEASE, COENZYME A, BIOSYNTHESIS, KINASE, ATP-DEPENDENT, TRANSFERASE
4i3g:B (ALA53) to (PRO84) CRYSTAL STRUCTURE OF DESR, A BETA-GLUCOSIDASE FROM STREPTOMYCES VENEZUELAE IN COMPLEX WITH D-GLUCOSE. | PA14 DOMAIN, BETA-GLUCOSIDASE, MACROLIDE ANTIBIOTIC, ANTIBIOTIC ACTIVATION, EXTRACELLULAR, HYDROLASE
4xia:B (PRO96) to (GLY137) STRUCTURES OF D-XYLOSE ISOMERASE FROM ARTHROBACTER STRAIN B3728 CONTAINING THE INHIBITORS XYLITOL AND D-SORBITOL AT 2.5 ANGSTROMS AND 2.3 ANGSTROMS RESOLUTION, RESPECTIVELY | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
3fng:A (THR196) to (LYS233) CRYSTAL STRUCTURE OF INHA BOUND TO TRICLOSAN DERIVATIVE | INHA, TRICLOSAN, TUBERCULOSIS, ANTIBIOTIC RESISTANCE, FATTY ACID BIOSYNTHESIS, LIPID SYNTHESIS, NAD, OXIDOREDUCTASE
1os5:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE COMPLEXED WITH A NOVEL NON-COMPETITIVE INHIBITOR. | ENZYME-INHIBITOR COMPLEX, TRANSFERASE
2qcf:A (SER226) to (ALA258) CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN (ASP312ASN MUTANT) OF HUMAN UMP SYNTHASE BOUND TO 5-FLUORO-UMP | UMP SYNTHASE, DECARBOXYLASE, CATALYTIC PROFICIENCY, LYASE
2qcn:B (SER226) to (ALA258) COVALENT COMPLEX OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE WITH 6-IODO-UMP | UMP SYNTHASE, DECARBOXYLASE, CATALYTIC PROFICIENCY, DISEASE MUTATION, GLYCOSYLTRANSFERASE, LYASE, MULTIFUNCTIONAL ENZYME, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
1p6b:B (PRO135) to (THR173) X-RAY STRUCTURE OF PHOSPHOTRIESTERASE, TRIPLE MUTANT H254G/H257W/L303T | METALLOENZYME, TIM BARREL, NERVE AGENTS, HYDROLASE
3sy8:C (PRO190) to (ASN233) CRYSTAL STRUCTURE OF THE RESPONSE REGULATOR ROCR | TIM BARREL PHOSPHODIESTERASE-A, TRANSCRIPTION REGULATOR
3sy8:D (PRO190) to (ASN233) CRYSTAL STRUCTURE OF THE RESPONSE REGULATOR ROCR | TIM BARREL PHOSPHODIESTERASE-A, TRANSCRIPTION REGULATOR
2ch6:A (GLY270) to (LYS306) CRYSTAL STRUCTURE OF HUMAN N-ACETYLGLUCOSAMINE KINASE IN COMPLEX WITH ADP AND GLUCOSE | TRANSFERASE, SUGAR KINASE, RIBONUCLEASE H FOLD, SUGAR KINASE/HSP70/ACTIN SUPERFAMILY
3g4d:A (ARG211) to (ARG272) CRYSTAL STRUCTURE OF (+)-DELTA-CADINENE SYNTHASE FROM GOSSYPIUM ARBOREUM AND EVOLUTIONARY DIVERGENCE OF METAL BINDING MOTIFS FOR CATALYSIS | CYCLASE, LYASE, MAGNESIUM, METAL-BINDING
1e0w:A (PRO90) to (VAL126) XYLANASE 10A FROM SREPTOMYCES LIVIDANS. NATIVE STRUCTURE AT 1.2 ANGSTROM RESOLUTION | XYLAN DEGRADATION, HYDROLASE
2d41:A (GLY188) to (ARG222) X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE INHIBITOR | HEPATITIS C VIRUS, RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
2d41:B (GLY188) to (ARG222) X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE INHIBITOR | HEPATITIS C VIRUS, RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
3tle:A (ALA28) to (LYS54) MICROCIN C7 SELF IMMUNITY PROTEIN MCCF IN COMPLEX WITH GLUTAMYL SULFAMOYL ADENYLATE | SERINE PROTEASE, HYDROLASE
3tlg:A (ALA28) to (LYS54) MICROCIN C7 SELF IMMUNITY PROTEIN MCCF IN THE INACTIVE MUTANT APO STATE | SERINE PROTEASE, HYDROLASE
1esj:A (GLY240) to (SER272) CRYSTAL STRUCTURE OF THIAZOLE KINASE MUTANT (C198S) | TRIMER, ALPHA-BETA PROTEIN, TRANSFERASE
1esj:B (GLY240) to (VAL269) CRYSTAL STRUCTURE OF THIAZOLE KINASE MUTANT (C198S) | TRIMER, ALPHA-BETA PROTEIN, TRANSFERASE
2rl2:A (PRO85) to (VAL111) CRYSTAL STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE FROM HAEMOPHILUS INFLUENZAE IN COMPLEX WITH UDP-N-ACETYLGLUCOSAMINE AND FOSFOMYCIN | MURA, MURZ, UDP-N-ACETYLGLUCOSAMINE, FOSFOMYCIN, CELL CYCLE, CELL DIVISION, CELL SHAPE, CELL WALL BIOGENESIS/DEGRADATION, CYTOPLASM, PEPTIDOGLYCAN SYNTHESIS, TRANSFERASE
1eyw:A (PRO135) to (THR173) THREE-DIMENSIONAL STRUCTURE OF THE ZINC-CONTAINING PHOSPHOTRIESTERASE WITH BOUND SUBSTRATE ANALOG TRIETHYLPHOSPHATE | HYDROLASE, ORGANOPHOSPHATE, ZINC
3tyq:A (GLY188) to (ARG222) SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3tyq:B (GLY188) to (ARG222) SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h5s:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3h5s:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3h5u:A (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR 1 | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3h5u:B (GLY188) to (ARG222) HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR 1 | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3u4o:A (GLY188) to (ARG222) NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE C2 ACYL SULFONAMIDES | NUCLEOTIDYL TRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3u4o:B (GLY188) to (ARG222) NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE C2 ACYL SULFONAMIDES | NUCLEOTIDYL TRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jy0:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 3 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jy0:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 3 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ues:A (GLU139) to (SER168) CRYSTAL STRUCTURE OF ALPHA-1,3/4-FUCOSIDASE FROM BIFIDOBACTERIUM LONGUM SUBSP. INFANTIS COMPLEXED WITH DEOXYFUCONOJIRIMYCIN | TIM BARREL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ues:B (GLU139) to (SER168) CRYSTAL STRUCTURE OF ALPHA-1,3/4-FUCOSIDASE FROM BIFIDOBACTERIUM LONGUM SUBSP. INFANTIS COMPLEXED WITH DEOXYFUCONOJIRIMYCIN | TIM BARREL, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ytr:A (ASP74) to (LEU108) CRYSTAL STRUCTURE OF D-TAGATOSE 3-EPIMERASE C66S FROM PSEUDOMONAS CICHORII IN COMPLEX WITH 1-DEOXY L-TAGATOSE | EPIMERASE, ISOMERASE
2vk9:A (LEU249) to (ASP284) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF ALPHA-TOXIN FROM CLOSTRIDIUM NOVYI | TOXIN, GLYCOSYLTRANSFERASE
2vkd:B (GLU249) to (ASP286) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF LETHAL TOXIN FROM CLOSTRIDIUM SORDELLII IN COMPLEX WITH UDP-GLC AND MANGANESE ION | TOXIN, GLYCOSYLTRANSFERASE
2vkd:C (GLU249) to (ASP286) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF LETHAL TOXIN FROM CLOSTRIDIUM SORDELLII IN COMPLEX WITH UDP-GLC AND MANGANESE ION | TOXIN, GLYCOSYLTRANSFERASE
1ggo:A (THR44) to (ARG96) T453A MUTANT OF PYRUVATE, PHOSPHATE DIKINASE | TRANSFERASE, PHOSPHOTRANSFERASE, KINASE
3hvo:A (GLY188) to (ARG222) STRUCTURE OF THE GENOTYPE 2B HCV POLYMERASE BOUND TO A NNI | VIRAL POLYMERASE, ATP-BINDING, HYDROLASE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE
3hvo:B (GLY188) to (ARG222) STRUCTURE OF THE GENOTYPE 2B HCV POLYMERASE BOUND TO A NNI | VIRAL POLYMERASE, ATP-BINDING, HYDROLASE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE
1s95:A (THR187) to (THR230) STRUCTURE OF SERINE/THREONINE PROTEIN PHOSPHATASE 5 | PROTEIN PHOSPHATASE, PPPASE, PP5, PHOSPHATE ANION, METAL ION, METALLOPHOSPHOESTERASE, HYDROLASE
1sbq:B (LYS3) to (ILE52) CRYSTAL STRUCTURE OF METHENYLTETRAHYDROFOLATE SYNTHETASE FROM MYCOPLASMA PNEUMONIAE AT 2.2 RESOLUTION | 5,10-METHENYLTETRAHYDROFOLATE SYNTHETASE, MTHFS, 5- FORMYLTETRAHYDROFOLATE CYCLO-LIGASE, STRUCTURAL GENOMICS, BSGC STRUCTURE FUNDED BY NIH, PROTEIN STRUCTURE INITIATIVE, PSI, BERKELEY STRUCTURAL GENOMICS CENTER
1gxb:A (MET157) to (PHE193) ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH PYROPHOSPHATE AND MAGNESIUM | TRANSFERASE, TRYPTOPHANE BIOSYNTHESIS, ANTHRANILATE PHOSPHORIBOSYL TRANSFERASE, PRPP, MG2+, PYROPHOSPHATE
1gxb:C (MET157) to (PHE193) ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH PYROPHOSPHATE AND MAGNESIUM | TRANSFERASE, TRYPTOPHANE BIOSYNTHESIS, ANTHRANILATE PHOSPHORIBOSYL TRANSFERASE, PRPP, MG2+, PYROPHOSPHATE
1gxb:D (MET157) to (PHE193) ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH PYROPHOSPHATE AND MAGNESIUM | TRANSFERASE, TRYPTOPHANE BIOSYNTHESIS, ANTHRANILATE PHOSPHORIBOSYL TRANSFERASE, PRPP, MG2+, PYROPHOSPHATE
4lac:C (LYS4) to (CYS50) CRYSTAL STRUCTURE OF PROTEIN PHOSPHATASE 2A (PP2A) AND PP2A PHOSPHATASE ACTIVATOR (PTPA) COMPLEX WITH ATPGAMMAS | PP2A, PTPA, PROTEIN PHOSPHATASE, SIGNALING PATHWAY REGULATION, CHAPERONE, HYDROLASE-SIGNALING PROTEIN COMPLEX
4zsu:A (PRO135) to (THR173) CRYSTAL STRUCTURE OF BREVUNDIMONAS DIMINUTA PHOSPHOTRIESTERASE MUTANT L7EP-3AG | BACTERIAL PROTEINS, ENZYMES, CATALYSIS, AMIDOHYDROLASE, CHEMICAL WARFARE AGENTS, VX NERVE AGENT, VR NERVE AGENT, HYDROLASE
2gvq:D (MET157) to (PHE193) ANTHRANILATE PHOSPHORIBOSYL-TRANSFERASE (TRPD) FROM S. SOLFATARICUS IN COMPLEX WITH ANTHRANILATE | PROTEIN-LIGAND COMPLEX, TRANSFERASE
1hlp:B (ASP237) to (PRO269) STRUCTURAL FEATURES STABILIZING HALOPHILIC MALATE DEHYDROGENASE FROM AN ARCHAEBACTERIUM | DEHYDROGENASE, HALOPHILIC
1hqe:A (ARG277) to (GLY316) HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 | NUCLEOTIDYLTRANSFERASE
2who:A (GLY188) to (THR221) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR | TRANSFERASE, RNA REPLICATION, ENVELOPE PROTEIN, HEPATITIS C VIRUS, ENDOPLASMIC RETICULUM, NON NUCLEOSIDE INHIBITOR, VIRAL PROTEIN, METAL-BINDING, TRANSMEMBRANE, POLYMERASE, ATP-BINDING, GENOTYPE 1B, RNA-BINDING, RNA-DEPENDENT RNA POLYMERASE, NNI, HCV, NS5B, MEMBRANE, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, ALLOSTERIC INHIBITOR, RNA-DIRECTED RNA POLYMERASE
2who:B (GLY188) to (THR221) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR | TRANSFERASE, RNA REPLICATION, ENVELOPE PROTEIN, HEPATITIS C VIRUS, ENDOPLASMIC RETICULUM, NON NUCLEOSIDE INHIBITOR, VIRAL PROTEIN, METAL-BINDING, TRANSMEMBRANE, POLYMERASE, ATP-BINDING, GENOTYPE 1B, RNA-BINDING, RNA-DEPENDENT RNA POLYMERASE, NNI, HCV, NS5B, MEMBRANE, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, ALLOSTERIC INHIBITOR, RNA-DIRECTED RNA POLYMERASE
2wjy:A (ILE850) to (GLY874) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN HUMAN NONSENSE MEDIATED DECAY FACTORS UPF1 AND UPF2 ORTHORHOMBIC FORM | NONSENSE MEDIATED DECAY, ZINC-FINGER, ATP-BINDING, METAL-BINDING, UPF2, UPF1, HELICASE, HYDROLASE, NONSENSE-MEDIATED MRNA DECAY, PHOSPHOPROTEIN, NUCLEOTIDE-BINDING
3w1j:C (PRO340) to (LYS377) CRYSTAL STRUCTURE OF THE N-TERMINAL TRUNCATED SELENOCYSTEINE SYNTHASE SELA IN COMPLEX WITH THIOSULFATE | HOMODECAMER, PENTAMER OF DIMERS, FOLD-TYPE I PYRIDOXAL 5'-PHOSPHATE (PLP) DEPENDENT ENZYME, L-SERYL-TRNA(SEC) SELENIUM TRANSFERASE, SELENOCYSTEINE SYNTHESIS, SELENIUM METABOLISM, TRANSFERASE
3w1j:E (PRO340) to (LYS377) CRYSTAL STRUCTURE OF THE N-TERMINAL TRUNCATED SELENOCYSTEINE SYNTHASE SELA IN COMPLEX WITH THIOSULFATE | HOMODECAMER, PENTAMER OF DIMERS, FOLD-TYPE I PYRIDOXAL 5'-PHOSPHATE (PLP) DEPENDENT ENZYME, L-SERYL-TRNA(SEC) SELENIUM TRANSFERASE, SELENOCYSTEINE SYNTHESIS, SELENIUM METABOLISM, TRANSFERASE
3w1j:J (PRO340) to (LYS377) CRYSTAL STRUCTURE OF THE N-TERMINAL TRUNCATED SELENOCYSTEINE SYNTHASE SELA IN COMPLEX WITH THIOSULFATE | HOMODECAMER, PENTAMER OF DIMERS, FOLD-TYPE I PYRIDOXAL 5'-PHOSPHATE (PLP) DEPENDENT ENZYME, L-SERYL-TRNA(SEC) SELENIUM TRANSFERASE, SELENOCYSTEINE SYNTHESIS, SELENIUM METABOLISM, TRANSFERASE
1umy:C (ALA48) to (THR73) BHMT FROM RAT LIVER | TRANSFERASE, METHIONINE SYNTHESIS, HOMOCYSTEINE METABOLISM, BETAINE, METHYLTRANSFERASE, ZINC
2ioh:A (THR214) to (GLU247) CRYSTAL STRUCTURE OF PHOSPHONOACETALDEHYDE HYDROLASE WITH A K53R MUTATION | PHOSPHONOACETALDEHYDE HYDROLASE, HALOACID DEHALOGENASE SUPERFAMILY, HYDROLASE
2ioh:B (THR214) to (GLU247) CRYSTAL STRUCTURE OF PHOSPHONOACETALDEHYDE HYDROLASE WITH A K53R MUTATION | PHOSPHONOACETALDEHYDE HYDROLASE, HALOACID DEHALOGENASE SUPERFAMILY, HYDROLASE
2ioh:C (THR214) to (GLU247) CRYSTAL STRUCTURE OF PHOSPHONOACETALDEHYDE HYDROLASE WITH A K53R MUTATION | PHOSPHONOACETALDEHYDE HYDROLASE, HALOACID DEHALOGENASE SUPERFAMILY, HYDROLASE
2ioh:D (THR214) to (GLU247) CRYSTAL STRUCTURE OF PHOSPHONOACETALDEHYDE HYDROLASE WITH A K53R MUTATION | PHOSPHONOACETALDEHYDE HYDROLASE, HALOACID DEHALOGENASE SUPERFAMILY, HYDROLASE
1j10:A (ASP236) to (VAL291) BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES IN COMPLEX WITH GGX | HYDROLASE, BETA-AMYLASE, RAW-STARCH BINDING DOMAIN
1j10:B (ASP236) to (VAL291) BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES IN COMPLEX WITH GGX | HYDROLASE, BETA-AMYLASE, RAW-STARCH BINDING DOMAIN
4mkf:B (GLY85) to (TYR109) CRYSTAL STRUCTURE OF A STABLE ADENYLATE KINASE VARIANT AKV3 | ADENYLATE KINASE, ZINC FINGER, TRANSFERASE ACTIVITY, PHOSPHOTRANSFERASE ACTIVITY, ZINC BINDING, ATP BINDING, PHOSPHORYLATION, TRANSFERASE
4mpk:A (SER210) to (PRO238) CRYSTAL STRUCTURE OF THE COMPLEX OF BUFFALO SIGNALING PROTEIN SPB-40 WITH N-ACETYLGLUCOSAMINE AT 2.65 A RESOLUTION | TEXT SPB-40, TIM BARREL, SIGNALING PROTEIN, N-ACETYLGLUCOSAMINE
3wql:A (SER5) to (PRO32) CRYSTAL STRUCTURE OF RV3378C WITH MG2+ AND PPI | PHOSPHATASE, DITERPENE SYNTHASE, HYDROLASE
3wql:C (SER5) to (PRO32) CRYSTAL STRUCTURE OF RV3378C WITH MG2+ AND PPI | PHOSPHATASE, DITERPENE SYNTHASE, HYDROLASE
3wql:D (SER5) to (PHE33) CRYSTAL STRUCTURE OF RV3378C WITH MG2+ AND PPI | PHOSPHATASE, DITERPENE SYNTHASE, HYDROLASE
3wqr:B (LYS300) to (VAL334) CRYSTAL STRUCTURE OF PFDXR COMPLEXED WITH INHIBITOR-12 | REDUCTOISOMERASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
1jle:B (ARG358) to (LYS390) CRYSTAL STRUCTURE OF Y188C MUTANT HIV-1 REVERSE TRANSCRIPTASE | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NON-NUCLEOSIDE INHIBITOR, DRUG RESISTANCE MUTATIONS, DRUG DESIGN, TRANSFERASE
1viy:A (ARG67) to (VAL111) CRYSTAL STRUCTURE OF DEPHOSPHO-COA KINASE | STRUCTURAL GENOMICS, TRANSFERASE
1viy:B (ARG67) to (PRO113) CRYSTAL STRUCTURE OF DEPHOSPHO-COA KINASE | STRUCTURAL GENOMICS, TRANSFERASE
2xhv:B (GLY188) to (ARG222) HCV-J4 NS5B POLYMERASE POINT MUTANT ORTHORHOMBIC CRYSTAL FORM | REPLICATION, TRANSCRIPTION, TRANSFERASE
4mz4:A (GLY188) to (ARG222) DISCOVERY OF AN IRREVERSIBLE HCV NS5B POLYMERASE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mz4:B (GLY188) to (ARG222) DISCOVERY OF AN IRREVERSIBLE HCV NS5B POLYMERASE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5b3a:B (GLY72) to (ARG101) CRYSTAL STRUCTURE OF O-PHOSHOSERINE SULFHYDRYLASE FROM AEROPYRUM PERNIX IN COMPLEXED WITH THE ALPHA-AMINOACRYLATE INTERMEDIATE | CYSTEINE BIOSYNTHESIS, SULFHYDRYLASE, INTERMEDIATE, EXTERNAL SCHIFF BASE OF PLP WITH ALPHA-AMINO ACRYLATE, TRANSFERASE
3zhx:A (GLU129) to (ASP151) STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS DXR IN COMPLEX WITH A FOSMIDOMYCIN ANALOGUE | OXIDOREDUCTASE, RV2870C, DOXP/MEP PATHWAY, ISPC
3zhx:B (GLU129) to (ASP151) STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS DXR IN COMPLEX WITH A FOSMIDOMYCIN ANALOGUE | OXIDOREDUCTASE, RV2870C, DOXP/MEP PATHWAY, ISPC
2yee:A (LYS191) to (GLU223) HSP90 INHIBITORS AND DRUGS FROM FRAGMENT AND VIRTUAL SCREENING | PU3, ATPASE, CHAPERONE, STRESS RESPONSE, NUCLEOTIDE-BINDING, ATP-BINDING, PHOSPHOPROTEIN, PHOSPHORYLATION
3zx3:D (ALA132) to (LYS167) CRYSTAL STRUCTURE AND DOMAIN ROTATION OF NTPDASE1 CD39 | HYDROLASE, DOMAIN ROTATION, PURINERGIC SIGNALING
2yl5:A (GLY815) to (PHE849) INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS | HYDROLASE
2yl5:B (GLY815) to (PHE849) INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS | HYDROLASE
2yl5:C (GLY815) to (PHE849) INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS | HYDROLASE
2yl5:D (GLY815) to (PHE849) INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS | HYDROLASE
2z7a:D (SER7) to (PRO41) X-RAY CRYSTAL STRUCTURE OF RV0760C FROM MYCOBACTERIUM TUBERCULOSIS AT 2.10 ANGSTROM RESOLUTION | ALPHA+BETA CONICAL BARREL, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, ISOMERASE
1xlt:G (ALA328) to (ASP371) CRYSTAL STRUCTURE OF TRANSHYDROGENASE [(DOMAIN I)2:DOMAIN III] HETEROTRIMER COMPLEX | TRANSHYDROGENASE, NAD, NADH, NADP, NADPH, OXIDOREDUCTASE
4owv:A (ARG187) to (ALA222) ANTHRANILATE PHOSPHORIBOSYL TRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH ANTHRANILATE | ANTHRANILIC ACIDS, MAGNESIUM, TRYPTOPHAN, INHIBITOR, TRANSFERASE
4owv:B (ARG187) to (ALA222) ANTHRANILATE PHOSPHORIBOSYL TRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH ANTHRANILATE | ANTHRANILIC ACIDS, MAGNESIUM, TRYPTOPHAN, INHIBITOR, TRANSFERASE
4aep:A (GLY188) to (ARG222) HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 1.8 ANGSTROM | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
4p7n:A (SER492) to (ASN538) STRUCTURE OF ESCHERICHIA COLI PGAB C-TERMINAL DOMAIN IN COMPLEX WITH GLUCOSAMINE | BETA ALPHA BARREL, CARBOHYDRATE BINDING, GLYCOSYL HYDROLASE FOLD, COMPLEX, HYDROLASE
5d6j:A (THR252) to (VAL280) CRYSTAL STRUCTURE OF A MYCOBACTERIAL PROTEIN | MYCOBACTERIUM SMEGMATIS, LIGASE-PROTEIN BINDING COMPLEX
4pfh:B (ASP74) to (LEU108) CRYSTAL STRUCTURE OF ENGINEERED D-TAGATOSE 3-EPIMERASE PCDTE-IDF8 | EPIMERASE, TIM-BARREL, ISOMERASE
1n2t:A (THR33) to (ILE84) C-DES MUTANT K223A WITH GLY COVALENTY LINKED TO THE PLP-COFACTOR | FES CLUSTER BIOSYNTHESIS, NIFS, PYRIDOXAL 5'-PHOSPHATE, INACTIVE MUTANT, LYASE
1n2t:B (THR33) to (ILE84) C-DES MUTANT K223A WITH GLY COVALENTY LINKED TO THE PLP-COFACTOR | FES CLUSTER BIOSYNTHESIS, NIFS, PYRIDOXAL 5'-PHOSPHATE, INACTIVE MUTANT, LYASE
1yvx:A (GLY188) to (ARG222) HEPATITIS C VIRUS RNA POLYMERASE GENOTYPE 2A IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | NS5B POLYMERASE GENOTYPE 2A, NON-NUCLEOSIDE INHIBITOR, VIRAL PROTEIN
4awq:B (LYS191) to (GLU223) COMPLEX OF HSP90 ATPASE DOMAIN WITH TROPANE DERIVED INHIBITORS | CHAPERONE
4ay8:A (TRP46) to (PRO75) SEMET-DERIVATIVE OF A METHYLTRANSFERASE FROM M. MAZEI | TRANSFERASE
4ay8:B (TRP46) to (PRO75) SEMET-DERIVATIVE OF A METHYLTRANSFERASE FROM M. MAZEI | TRANSFERASE
4q7i:A (ASP74) to (LEU108) CRYSTAL STRUCTURE OF ENGINEERED THERMOSTABLE D-TAGATOSE 3-EPIMERASE PCDTE-VAR8 | EPIMERASE, TIM-BARREL, ISOMERASE
4q7i:B (ASP74) to (LEU108) CRYSTAL STRUCTURE OF ENGINEERED THERMOSTABLE D-TAGATOSE 3-EPIMERASE PCDTE-VAR8 | EPIMERASE, TIM-BARREL, ISOMERASE
3mi2:A (SER37) to (ALA69) CRYSTAL STRUCTURE OF HUMAN OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH PYRAZOFURIN MONOPHOSPHATE | UMP SYNTHASE, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, PYRAZOFURIN MONOPHOSPHATE, LYASE
3mi2:B (SER37) to (ALA69) CRYSTAL STRUCTURE OF HUMAN OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH PYRAZOFURIN MONOPHOSPHATE | UMP SYNTHASE, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, PYRAZOFURIN MONOPHOSPHATE, LYASE
3bgv:C (VAL122) to (THR153) CRYSTAL STRUCTURE OF MRNA CAP GUANINE-N7 METHYLTRANSFERASE IN COMPLEX WITH SAH | METHYLTRANSFERASE, ALTERNATIVE SPLICING, MRNA CAPPING, MRNA PROCESSING, NUCLEUS, PHOSPHOPROTEIN, RNA-BINDING, S- ADENOSYL-L-METHIONINE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
3bsc:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN
5f7p:E (ASP293) to (GLY337) ROK REPRESSOR LMO0178 FROM LISTERIA MONOCYTOGENES | REPRESSOR, OPEN READING FRAME, KINASE, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, TRANSCRIPTION
4bqp:A (THR196) to (LYS233) MTB INHA COMPLEX WITH METHYL-THIAZOLE COMPOUND 7 | OXIDOREDUCTASE, ACP ENOYL REDUCTASE
4bqp:B (THR196) to (LYS233) MTB INHA COMPLEX WITH METHYL-THIAZOLE COMPOUND 7 | OXIDOREDUCTASE, ACP ENOYL REDUCTASE
4bqp:C (THR196) to (LYS233) MTB INHA COMPLEX WITH METHYL-THIAZOLE COMPOUND 7 | OXIDOREDUCTASE, ACP ENOYL REDUCTASE
4bqp:D (THR196) to (LYS233) MTB INHA COMPLEX WITH METHYL-THIAZOLE COMPOUND 7 | OXIDOREDUCTASE, ACP ENOYL REDUCTASE
3cde:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, ATP-BINDING, HOST-VIRUS INTERACTION, HYDROLASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION
3cde:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, ATP-BINDING, HOST-VIRUS INTERACTION, HYDROLASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION
3cj2:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj2:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
4ce2:A (LYS178) to (THR210) HSP90 N-TERMINAL DOMAIN BOUND TO MACROLACTAM ANALOGUES OF RADICICOL. | CHAPERONE
3co9:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, NUCLEOTIDE BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSFERASE, ANTIVIRAL, HYDROLASE, NUCLEOTIDE-BINDING
3co9:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, NUCLEOTIDE BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSFERASE, ANTIVIRAL, HYDROLASE, NUCLEOTIDE-BINDING
5fun:A (ASP630) to (ARG679) CRYSTAL STRUCTURE OF HUMAN JARID1B IN COMPLEX WITH GSK467 | OXIDOREDUCTASE, LYSINE-SPECIFIC DEMETHYLASE 5B
5fv3:A (ASP630) to (ARG679) CRYSTAL STRUCTURE OF HUMAN JARID1B CONSTRUCT C2 IN COMPLEX WITH N-OXALYLGLYCINE. | OXIDOREDUCTASE, JARID1B, PLU1
3cvk:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE
3cvk:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE
5fyt:A (SER628) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH 3D FRAGMENT (5-FLUORO-2-OXO-2,3-DIHYDRO-1H-INDOL-3-YL)ACETIC ACID (N09996A) | OXIDOREDUCTASE, JARID1B, PLU1, PANDDA, FRAGMENT SOAKING, X-RAY FRAGMENT SCREENING, STRUCTURAL GENOMICS CONSORTIUM, SGC
5fzh:A (ASP630) to (ARG679) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH MAYBRIDGE FRAGMENT 4,5-DIHYDRONAPHTHO(1,2- B)THIOPHENE-2-CARBOXYLICACID (N11181A) (LIGAND MODELLED BASED ON PANDDA EVENT MAP, SGC - DIAMOND I04-1 FRAGMENT SCREENING) | OXIDOREDUCTASE, JARID1B, PLU1, FRAGMENT SCREENING, STRUCTURAL GENOMICS CONSORTIUM, SGC, DIAMOND I04-1, PANDDA
5g0w:A (ALA198) to (LYS233) INHA IN COMPLEX WITH A DNA ENCODED LIBRARY HIT | OXIDOREDUCTASE, INHA, ACP ENOYL REDUCTASE, DNA ENCODED LIBRARY, DEL, TUBERCULOSIS
5g0w:B (ALA198) to (LYS233) INHA IN COMPLEX WITH A DNA ENCODED LIBRARY HIT | OXIDOREDUCTASE, INHA, ACP ENOYL REDUCTASE, DNA ENCODED LIBRARY, DEL, TUBERCULOSIS
5g0w:D (ALA198) to (LYS233) INHA IN COMPLEX WITH A DNA ENCODED LIBRARY HIT | OXIDOREDUCTASE, INHA, ACP ENOYL REDUCTASE, DNA ENCODED LIBRARY, DEL, TUBERCULOSIS
4cwo:A (LYS191) to (GLU225) HUMAN HSP90 ALPHA N-TERMINAL DOMAIN IN COMPLEX WITH AN AMINOTRIAZOLOQUINAZOLINE INHIBITOR | CHAPERONE
3dbn:A (LYS175) to (PRO223) CRYSTAL STRUCTURE OF THE STREPTOCCOCUS SUIS SEROTYPE2 D- MANNONATE DEHYDRATASE IN COMPLEX WITH ITS SUBSTRATE | TIM BARREL, LYASE
4trm:E (LEU197) to (LYS233) STRUCTURE OF THE APO FORM OF INHA FROM MYCOBACTERIUM TUBERCULOSIS | ENOYL REDUCTASE, OXIDOREDUCTASE
3dla:A (ILE60) to (GLY94) X-RAY CRYSTAL STRUCTURE OF GLUTAMINE-DEPENDENT NAD+ SYNTHETASE FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO NAAD+ AND DON | GLUTAMINASE, NAD+ SYNTHETASE, AMMONIA TUNNELING, ENZYME, GLUTAMINE- DEPENDENT NAD+ SYNTHETASE, GLUTAMINE-AMIDO TRANSFERASE, ATP-BINDING, LIGASE, NAD, NUCLEOTIDE-BINDING
3dla:D (ILE60) to (GLY94) X-RAY CRYSTAL STRUCTURE OF GLUTAMINE-DEPENDENT NAD+ SYNTHETASE FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO NAAD+ AND DON | GLUTAMINASE, NAD+ SYNTHETASE, AMMONIA TUNNELING, ENZYME, GLUTAMINE- DEPENDENT NAD+ SYNTHETASE, GLUTAMINE-AMIDO TRANSFERASE, ATP-BINDING, LIGASE, NAD, NUCLEOTIDE-BINDING
5hfu:A (PRO115) to (PHE154) CRYSTAL STRUCTURE OF HUMAN HEXOKINASE 2 WITH CMPD 27, A 2-AMIDO-6- BENZENESULFONAMIDE GLUCOSAMINE | METABOLISM, INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3p0j:D (THR237) to (ILE293) LEISHMANIA MAJOR TYROSYL-TRNA SYNTHETASE IN COMPLEX WITH TYROSINOL, TRICLINIC CRYSTAL FORM 1 | AMINOACYL-TRNA SYNTHETASE, TRNA LIGASE, AARS, TYRRS, PSEUDODIMER, TRANSLATION, ATP-BINDING, NUCLEOTIDE-BINDING, LIGASE, STRUCTURAL GENOMICS, MEDICAL STRUCTURAL GENOMICS OF PATHOGENIC PROTOZOA, MSGPP
4eo8:A (GLY188) to (ARG222) HCV NS5B POLYMERASE INHIBITORS: TRI-SUBSTITUTED ACYLHYDRAZINES AS TERTIARY AMIDE BIOISOSTERES | HCV, NS5B, RNA, RNA POLYMERASE, POLYMERASE INHIBITOR, THUMB SITE 2 INHIBITOR, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eo8:B (GLY188) to (ARG222) HCV NS5B POLYMERASE INHIBITORS: TRI-SUBSTITUTED ACYLHYDRAZINES AS TERTIARY AMIDE BIOISOSTERES | HCV, NS5B, RNA, RNA POLYMERASE, POLYMERASE INHIBITOR, THUMB SITE 2 INHIBITOR, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3r20:A (GLY93) to (GLY131) CRYSTAL STRUCTURE OF CYTIDYLATE KINASE FROM MYCOBACTERIUM SMEGMATIS | STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, CYTIDYLATE KINASE, ADP, DCMP, DCDP, TRANSFERASE
3rg2:E (HIS130) to (LEU154) STRUCTURE OF A TWO-DOMAIN NRPS FUSION PROTEIN CONTAINING THE ENTE ADENYLATION DOMAIN AND ENTB ARYL-CARRIER PROTEIN FROM ENTEROBACTIN BIOSYNTHESIS | ADENYLATE-FORMING ENZYMES, ANL SUPERFAMILY, NON-RIBOSOMAL PEPTIDE SYNTHETASE CARRIER PROTEIN FUNCTION, NRPS ADENYLATION DOMAIN ACYL CARRIER PROTEIN, 4'PHOSPHOPANTETHEINYLATION 4'PP COFACTOR, LIGASE
4gmc:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH A THUMB INHIBITOR | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5kyy:A (ILE664) to (HIS710) CRYSTAL STRUCTURE OF SEC23 AND TANGO1 PEPTIDE4 COMPLEX | COPII COAT, COLLAGEN SECRETION, CARGO ADAPTER, VESICLE, PROTEIN TRANSPORT
5tri:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 3-[(4-CHLOROPHENYL)METHOXY]-2-(1-OXO-1,3- DIHYDRO-2H-ISOINDOL-2-YL)BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5tri:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 3-[(4-CHLOROPHENYL)METHOXY]-2-(1-OXO-1,3- DIHYDRO-2H-ISOINDOL-2-YL)BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trj:A (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-{[2-(CARBOXYMETHOXY)BENZENE-1- CARBONYL]AMINO}-3-[(4-CHLOROPHENYL)METHOXY]BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trj:B (GLY188) to (ARG222) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-{[2-(CARBOXYMETHOXY)BENZENE-1- CARBONYL]AMINO}-3-[(4-CHLOROPHENYL)METHOXY]BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX