2o8s:A (THR105) to (ALA140) X-RAY CRYSTAL STRUCTURE OF PROTEIN AGR_C_984 FROM AGROBACTERIUM TUMEFACIENS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ATR120. | ALL ALPHA-HELICAL PROTEIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
2o8s:B (THR105) to (ALA140) X-RAY CRYSTAL STRUCTURE OF PROTEIN AGR_C_984 FROM AGROBACTERIUM TUMEFACIENS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ATR120. | ALL ALPHA-HELICAL PROTEIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
4wbz:A (SER168) to (LEU200) TRNA-PROCESSING ENZYME (APO FORM 2) | RNA NUCLEOTIDYLTRANSFERASE, CCA-ADDING ENZYME, A-ADDING ENZYME, TRANSFERASE
2aja:A (ALA190) to (LEU219) X-RAY STRUCTURE OF AN ANKYRIN REPEAT FAMILY PROTEIN Q5ZSV0 FROM LEGIONELLA PNEUMOPHILA. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET LGR21. | X-RAY STRUCTURE, NESG, Q5ZSV0, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, PROTEIN BINDING
1a49:E (TYR3369) to (LYS3421) BIS MG-ATP-K-OXALATE COMPLEX OF PYRUVATE KINASE | TRANSFERASE, PYRUVATE KINASE, RABBIT MUSCLE, DOMAIN MOVEMENT, POTASSIUM BINDING
1nb4:A (SER478) to (TYR524) HC-J4 RNA POLYMERASE APO-FORM | HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE
1nb4:B (SER478) to (LEU525) HC-J4 RNA POLYMERASE APO-FORM | HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE
1nb6:A (SER478) to (ARG523) HC-J4 RNA POLYMERASE COMPLEXED WITH UTP | HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE
1nb6:B (SER478) to (TYR524) HC-J4 RNA POLYMERASE COMPLEXED WITH UTP | HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE
2ode:A (SER62) to (VAL109) CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF HUMAN RGS8 AND ACTIVATED GI ALPHA 3 | G PROTEIN SIGNALLING, RGS, HETEROTRIMERIC G PROTEIN, SIGNALLING COMPLEX, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, SIGNALING PROTEIN
2ode:C (SER62) to (LEU110) CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF HUMAN RGS8 AND ACTIVATED GI ALPHA 3 | G PROTEIN SIGNALLING, RGS, HETEROTRIMERIC G PROTEIN, SIGNALLING COMPLEX, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, SIGNALING PROTEIN
4gun:I (LEU20) to (ASN86) CRYSTAL STRUCTURE OF THE K184R, L185P MUTANT MANGANESE SUPEROXIDE DISMUTASE FROM CANDIDA ALBICANS CYTOSOL | MN SUPEROXIDE DISMUTASE, OXIDOREDUCTASE
4gun:L (LEU20) to (ASN86) CRYSTAL STRUCTURE OF THE K184R, L185P MUTANT MANGANESE SUPEROXIDE DISMUTASE FROM CANDIDA ALBICANS CYTOSOL | MN SUPEROXIDE DISMUTASE, OXIDOREDUCTASE
4wfd:A (LEU9) to (ASP61) STRUCTURE OF THE RRP6-RRP47-MTR4 INTERACTION | RRP6-RRP47 COMPLEX, NUCLEAR EXOSOME, RNA DEGRADATION, RNA PROCESSING, HYDROLASE
3eab:F (ALA139) to (LEU192) CRYSTAL STRUCTURE OF SPASTIN MIT IN COMPLEX WITH ESCRT III | SPASTIN, CHMP, MIT, ESCRT, ALTERNATIVE SPLICING, ATP- BINDING, CYTOPLASM, DISEASE MUTATION, HEREDITARY SPASTIC PARAPLEGIA, NUCLEOTIDE-BINDING, NUCLEUS, POLYMORPHISM, CELL CYCLE
3rnb:A (LEU76) to (ALA101) STRUCTURE OF THE TOLUENE/O-XYLENE MONOOXYGENASE HYDROXYLASE T201S/F176W DOUBLE MUTANT | TOLUENE, HYDROXYLASE, FOUR-HELIX BUNDLE, DIIRON, OXYGEN PATHWAY, OXIDOREDUCTASE
3rne:A (LEU76) to (GLY98) STRUCTURE OF THE TOLUENE/O-XYLENE MONOOXYGENASE HYDROXYLASE T201S/I276E DOUBLE MUTANT | TOLUENE, HYDROXYLASE, FOUR-HELIX BUNDLE, DIIRON, OXYGEN PATHWAY, OXIDOREDUCTASE
3rnf:A (LEU76) to (GLY98) STRUCTURE OF THE TOLUENE/O-XYLENE MONOOXYGENASE HYDROXYLASE T201S/V271A DOUBLE MUTANT | TOLUENE, HYDROXYLASE, FOUR-HELIX BUNDLE, DIIRON, OXYGEN PATHWAY, OXIDOREDUCTASE
3rng:A (LEU76) to (GLY98) STRUCTURE OF THE TOLUENE/O-XYLENE MONOOXYGENASE HYDROXYLASE T201S/W167E DOUBLE MUTANT | TOLUENE, HYDROXYLASE, FOUR-HELIX BUNDLE, DIIRON, OXYGEN PATHWAY, OXIDOREDUCTASE
2an5:A (VAL23) to (PRO50) STRUCTURE OF HUMAN PNMT COMPLEXED WITH S-ADENOSYL- HOMOCYSTEINE AND AN INHIBITOR, TRANS-(1S,2S)-2-AMINO-1- TETRALOL | METHYLTRANSFERASE, INHIBITOR STRUCTURE, S-ADENOSYL-L- METHIONINE, ADRENALINE SYNTHESIS
3rqe:D (GLY57) to (ILE117) CEREBRAL CAVERNOUS MALFORMATION 3 (CCM3) IN COMPLEX WITH PAXILLIN LD1 | PROTEIN-PEPTIDE COMPLEX, PROTEIN BINDING, FAT DOMAIN, DIMERIZATION, CEREBRAL CAVERNOUS MALFORMATION
1aa6:A (THR477) to (THR516) REDUCED FORM OF FORMATE DEHYDROGENASE H FROM E. COLI | OXIDOREDUCTASE, SELENIUM, SELENOCYSTEINE, SECYS, MOLYBDENUM, MOLYBDOPTERIN, MPT, MOLYBDOPTERIN GUANINE DINUCLEOTIDE, MGD, IRON SULFUR CLUSTER, FE4S4, FORMATE, DEHYDROGENASE, ANAEROBIC
1nhu:A (SER478) to (LYS523) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
1nhu:B (SER478) to (LYS523) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
1nhv:A (PRO479) to (PHE526) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
1nhv:B (PRO479) to (TYR524) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
1nhy:A (ASP76) to (TYR150) CRYSTAL STRUCTURE OF THE GST-LIKE DOMAIN OF ELONGATION FACTOR 1-GAMMA FROM SACCHAROMYCES CEREVISIAE. | PROTEIN SYNTHESIS, GST-LIKE, TRANSLATION
1afr:D (ASN277) to (LEU337) STEAROYL-ACYL CARRIER PROTEIN DESATURASE FROM CASTOR SEEDS | OXIDOREDUCTASE, FATTY ACID DESATURASE, FATTY ACID BIOSYNTHESIS, BINUCLEAR IRON CENTER, ELECTRON TRANSFER
2awz:A (SER478) to (LYS523) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5H) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
2ax0:A (SER478) to (LYS523) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5X) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
2ax1:A (SER478) to (LYS523) HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5EE) | HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE
4gzy:D (ALA458) to (SER505) CRYSTAL STRUCTURES OF BACTERIAL RNA POLYMERASE PAUSED ELONGATION COMPLEXES | RNA POLYMERASE, TRANSCRIPTION, PAUSED TRANSCRIPTION ELONGATION COMPLEX, TRANSCRIPTIONAL PAUSING, DNA DIRECTED RNA TRANSCRIPTION, TRANSCRIPTION-DNA-RNA COMPLEX
4wlq:A (VAL255) to (LYS314) CRYSTAL STRUCTURE OF MUCH37-HRPN13 CTD COMPLEX | UCH37 RPN13 PROTEASOME INO80 DUB
2b0t:A (ASP673) to (PRO725) STRUCTURE OF MONOMERIC NADP ISOCITRATE DEHYDROGENASE | MONOMERIC, NADP, IDH, OXIDOREDUCTASE
2opo:D (THR44) to (PHE86) CRYSTAL STRUCTURE OF THE CALCIUM-BINDING POLLEN ALLERGEN CHE A 3 | CALCIUM-BINDING PROTEIN, DIMER, DOMAIN-SWAPPING, EF-HAND, ALLERGEN
4h1u:A (THR282) to (GLU729) NUCLEOTIDE-FREE HUMAN DYNAMIN-1-LIKE PROTEIN GTPASE-GED FUSION | GTPASE DOMAIN, GTPASE, HYDROLASE
4wot:A (ALA22) to (GLU76) ROCK2 IN COMPLEX WITH 1426382-07-1 | TRANSFERASE
4wot:B (GLY23) to (TYR75) ROCK2 IN COMPLEX WITH 1426382-07-1 | TRANSFERASE
4wot:C (GLY23) to (TYR75) ROCK2 IN COMPLEX WITH 1426382-07-1 | TRANSFERASE
4wot:D (GLY23) to (TYR75) ROCK2 IN COMPLEX WITH 1426382-07-1 | TRANSFERASE
4wqs:D (ALA458) to (GLY506) THERMUS THERMOPHILUS RNA POLYMERASE BACKTRACKED COMPLEX | TRANSCRIPTION, RNA CLEAVAGE, TRANSFERASE-DNA-RNA COMPLEX
2b3y:B (ASN23) to (TRP66) STRUCTURE OF A MONOCLINIC CRYSTAL FORM OF HUMAN CYTOSOLIC ACONITASE (IRP1) | IRP1 IRE-IRP1 ACONITASE ACTIVITY, LYASE
1ar4:B (LEU15) to (ASN81) X-RAY STRUCTURE ANALYSIS OF THE CAMBIALISTIC SUPEROXIDE DISMUTASE FROM PROPIONIBACTERIUM SHERMANII ACTIVE WITH FE OR MN | SUPEROXIDE DISMUTASE, OXIDOREDUCTASE, DEGRADES O2-, DISMUTASE
3eml:A (ASP1159) to (TYR290) THE 2.6 A CRYSTAL STRUCTURE OF A HUMAN A2A ADENOSINE RECEPTOR BOUND TO ZM241385. | ADENOSINE, CAFFEINE, GPCR, MEMBRANE PROTEIN, RECEPTOR, LCP, MESOPHASE, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, ACCELERATED TECHNOLOGIES CENTER FOR GENE TO 3D STRUCTURE, ATCG3D
1nw1:B (GLU342) to (HIS418) CRYSTAL STRUCTURE OF CHOLINE KINASE | CHOLINE KINASE, PHOSPHOLIPID SYNTHESIS, PROTEIN KINASE FOLD, TRANSFERASE
4wt9:A (SER478) to (ASN527) APO CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH E86Q E87Q S15G C223H V321I AND DELTA8 MUTATIONS | HCV, VIRAL, NS5B, RDRP, RESISTANCE MUTATION, DELTA8 BETA HAIRPIN LOOP DELETION, TRANSFERASE
4haw:C (PRO922) to (ASN969) CRYSTAL STRUCTURE OF CRM1 INHIBITOR LEPTOMYCIN B IN COMPLEX WITH CRM1(K548A)-RAN-RANBP1 | HEAT REPEAT, NUCLEAR EXPORT, RAN-RANBP1, LMB, LEPTOMYCIN B, PROTEIN TRANSPORT-ANTIBIOTIC COMPLEX
3eql:D (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC MYXOPYRONIN | RNA POLYMERASE HOLOENZYME, MYXOPYRONIN, ANTIBIOTIC, TRANSCRIPTION REGULATION, DNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, TRANSFERASE, DNA- BINDING, SIGMA FACTOR
3eql:N (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC MYXOPYRONIN | RNA POLYMERASE HOLOENZYME, MYXOPYRONIN, ANTIBIOTIC, TRANSCRIPTION REGULATION, DNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, TRANSFERASE, DNA- BINDING, SIGMA FACTOR
3s28:A (GLU230) to (VAL275) THE CRYSTAL STRUCTURE OF SUCROSE SYNTHASE-1 IN COMPLEX WITH A BREAKDOWN PRODUCT OF THE UDP-GLUCOSE | GLYCOSYLTRANSFERASE, SUCROSE METABOLISM, SUGAR DONAR COMPLEX, ROSSMANN FOLD, GT-B FOLD, GLYCOSYLTANSFERASE, UDP-GLUCOSE, CYTOSOL, TRANSFERASE
3s28:B (GLU230) to (VAL275) THE CRYSTAL STRUCTURE OF SUCROSE SYNTHASE-1 IN COMPLEX WITH A BREAKDOWN PRODUCT OF THE UDP-GLUCOSE | GLYCOSYLTRANSFERASE, SUCROSE METABOLISM, SUGAR DONAR COMPLEX, ROSSMANN FOLD, GT-B FOLD, GLYCOSYLTANSFERASE, UDP-GLUCOSE, CYTOSOL, TRANSFERASE
3s28:E (GLU230) to (VAL275) THE CRYSTAL STRUCTURE OF SUCROSE SYNTHASE-1 IN COMPLEX WITH A BREAKDOWN PRODUCT OF THE UDP-GLUCOSE | GLYCOSYLTRANSFERASE, SUCROSE METABOLISM, SUGAR DONAR COMPLEX, ROSSMANN FOLD, GT-B FOLD, GLYCOSYLTANSFERASE, UDP-GLUCOSE, CYTOSOL, TRANSFERASE
3s28:F (GLU230) to (VAL275) THE CRYSTAL STRUCTURE OF SUCROSE SYNTHASE-1 IN COMPLEX WITH A BREAKDOWN PRODUCT OF THE UDP-GLUCOSE | GLYCOSYLTRANSFERASE, SUCROSE METABOLISM, SUGAR DONAR COMPLEX, ROSSMANN FOLD, GT-B FOLD, GLYCOSYLTANSFERASE, UDP-GLUCOSE, CYTOSOL, TRANSFERASE
3s28:G (GLU230) to (VAL275) THE CRYSTAL STRUCTURE OF SUCROSE SYNTHASE-1 IN COMPLEX WITH A BREAKDOWN PRODUCT OF THE UDP-GLUCOSE | GLYCOSYLTRANSFERASE, SUCROSE METABOLISM, SUGAR DONAR COMPLEX, ROSSMANN FOLD, GT-B FOLD, GLYCOSYLTANSFERASE, UDP-GLUCOSE, CYTOSOL, TRANSFERASE
2p63:A (ASP228) to (ARG272) SUPRAFACIAL ORIENTATION OF THE SCFCDC4 DIMER ACCOMMODATES MULTIPLE GEOMETRIES FOR SUBSTRATE UBIQUITINATION | UBIQUITINATION, HELIX BUNDLE, SCF COMPLEX, CELL CYCLE
2p63:C (SER227) to (LEU270) SUPRAFACIAL ORIENTATION OF THE SCFCDC4 DIMER ACCOMMODATES MULTIPLE GEOMETRIES FOR SUBSTRATE UBIQUITINATION | UBIQUITINATION, HELIX BUNDLE, SCF COMPLEX, CELL CYCLE
2be5:D (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH INHIBITOR TAGETITOXIN | RNA POLYMERASE HOLOENZYME, TAGETITOXIN, ANTIBIOTIC, TRANSCRIPTION REGULATION, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
2be5:N (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH INHIBITOR TAGETITOXIN | RNA POLYMERASE HOLOENZYME, TAGETITOXIN, ANTIBIOTIC, TRANSCRIPTION REGULATION, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
2p6u:A (ASP575) to (LYS624) APO STRUCTURE OF THE HEL308 SUPERFAMILY 2 HELICASE | ARCHAEAL HELICASE, SF2 HELICASE, DNA REPAIR, DNA BINDING PROTEIN
4wz5:A (GLU129) to (VAL193) CRYSTAL STRUCTURE OF P. AERUGINOSA OXA10 | BETA LACTAMASE, INHIBTOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4wz5:B (GLU129) to (VAL193) CRYSTAL STRUCTURE OF P. AERUGINOSA OXA10 | BETA LACTAMASE, INHIBTOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4wz5:C (GLU129) to (VAL193) CRYSTAL STRUCTURE OF P. AERUGINOSA OXA10 | BETA LACTAMASE, INHIBTOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4wz5:D (GLU129) to (VAL193) CRYSTAL STRUCTURE OF P. AERUGINOSA OXA10 | BETA LACTAMASE, INHIBTOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3euq:A (ASN65) to (ARG106) X-RAY STRUCTURAL OF A TYPE III PENTAKETIDE SYNTHASE FROM NEUROSPORA CRASSA | ALPHA HELIX, ACYLTRANSFERASE, TRANSFERASE
3evk:A (LEU30) to (ASN96) CRYSTAL STRUCTURE OF THE METAL-BOUND SUPEROXIDE DISMUTASE FROM PYROBACULUM AEROPHILUM | ALPHA-BETA, IRON, METAL-BINDING, OXIDOREDUCTASE
3evk:B (LEU30) to (ASN96) CRYSTAL STRUCTURE OF THE METAL-BOUND SUPEROXIDE DISMUTASE FROM PYROBACULUM AEROPHILUM | ALPHA-BETA, IRON, METAL-BINDING, OXIDOREDUCTASE
3ew9:A (PRO13) to (ASP61) RADA RECOMBINASE FROM METHANOCOCCUS MARIPALUDIS IN COMPLEX WITH AMPPNP AND POTASSIUM IONS | RADA, STRAND EXCHANGE PROTEIN, ATPASE, RECOMBINASE, ATP ANALOGUE, ATP-BINDING, DNA DAMAGE, DNA RECOMBINATION, DNA- BINDING, NUCLEOTIDE-BINDING, DNA BINDING PROTEIN, RECOMBINATION
3s4w:A (SER554) to (ARG614) STRUCTURE OF THE FANCI-FANCD2 COMPLEX | DNA REPAIR, DNA BINDING PROTEIN
2pe6:A (THR108) to (PHE155) NON-COVALENT COMPLEX BETWEEN HUMAN SUMO-1 AND HUMAN UBC9 | SUMO, UBIQUITIN-LIKE, CONJUGATION, SMT3, UBC9, PROTEIN BINDING, LIGASE
3f2r:B (THR371) to (LEU455) CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE ALPHA IN COMPLEX WITH HEMICHOLINIUM-3 | NON-PROTEIN KINASE, CHOLINE KINASE, STRUCTURAL GENOMICS CONSORTIUM, SGC, HEMICHOLINIUM-3, ALTERNATIVE SPLICING, CYTOPLASM, KINASE, TRANSFERASE
2bmm:A (THR35) to (TYR67) X-RAY STRUCTURE OF A NOVEL THERMOSTABLE HEMOGLOBIN FROM THE ACTINOBACTERIUM THERMOBIFIDA FUSCA | BACTERIAL HEMOGLOBIN, THERMOSTABLE PROTEIN, OXYGEN STORAGE/TRANSPORT
4hns:A (MET63) to (PRO85) CRYSTAL STRUCTURE OF ACTIVATED CHEY3 OF VIBRIO CHOLERAE | ROSSMANN FOLD, RESPONSE REGULATOR, KINASE, BEF3 AND MG+2 BOUND, SIGNALING PROTEIN
3f7p:A (THR186) to (GLN240) CRYSTAL STRUCTURE OF A COMPLEX BETWEEN INTEGRIN BETA4 AND PLECTIN | INTEGRIN, PLAKIN, HEMIDESMOSOME, CELL ADHESION, EPIDERMOLYSIS BULLOSA, ACTIN-BINDING, ALTERNATIVE SPLICING, COILED COIL, CYTOPLASM, CYTOSKELETON, DISEASE MUTATION, PHOSPHOPROTEIN, STRUCTURAL PROTEIN, GLYCOPROTEIN, MEMBRANE, POLYMORPHISM, RECEPTOR, TRANSMEMBRANE, STRUCTURAL PROTEIN/CELL ADHESION COMPLEX
3f7p:B (THR186) to (GLN240) CRYSTAL STRUCTURE OF A COMPLEX BETWEEN INTEGRIN BETA4 AND PLECTIN | INTEGRIN, PLAKIN, HEMIDESMOSOME, CELL ADHESION, EPIDERMOLYSIS BULLOSA, ACTIN-BINDING, ALTERNATIVE SPLICING, COILED COIL, CYTOPLASM, CYTOSKELETON, DISEASE MUTATION, PHOSPHOPROTEIN, STRUCTURAL PROTEIN, GLYCOPROTEIN, MEMBRANE, POLYMORPHISM, RECEPTOR, TRANSMEMBRANE, STRUCTURAL PROTEIN/CELL ADHESION COMPLEX
3s8f:A (TYR52) to (ASN127) 1.8 A STRUCTURE OF BA3 CYTOCHROME C OXIDASE FROM THERMUS THERMOPHILUS IN LIPID ENVIRONMENT | COMPLEX IV, RESPIRATORY CHAIN, LIPID CUBIC PHASE, MONOOLEIN, PEROXIDE, ELECTRON TRANSPORT, PROTON PUMP, OXIDOREDUCTASE, MEMBRANE
1bs3:A (LEU15) to (ASN81) P.SHERMANII SOD(FE+3) FLUORIDE | SUPEROXIDE DISMUTASE, FLUORIDE, OXIDOREDUCTASE
1bs3:B (LEU15) to (ASN81) P.SHERMANII SOD(FE+3) FLUORIDE | SUPEROXIDE DISMUTASE, FLUORIDE, OXIDOREDUCTASE
1bsm:A (LEU15) to (ASN81) P.SHERMANII SOD(FE+3) 140K PH8 | SUPEROXIDE DISMUTASE, OXIDOREDUCTASE
1bsm:B (LEU15) to (ASN81) P.SHERMANII SOD(FE+3) 140K PH8 | SUPEROXIDE DISMUTASE, OXIDOREDUCTASE
1bt8:A (LEU15) to (ASN81) P.SHERMANII SOD(FE+3) PH 10.0 | OXIDOREDUCTASE, SUPEROXIDE DISMUTASE
1bt8:B (LEU15) to (ASN81) P.SHERMANII SOD(FE+3) PH 10.0 | OXIDOREDUCTASE, SUPEROXIDE DISMUTASE
3fa3:E (THR271) to (GLY299) CRYSTAL STRUCTURE OF 2,3-DIMETHYLMALATE LYASE, A PEP MUTASE/ISOCITRATE LYASE SUPERFAMILY MEMBER, TRIGONAL CRYSTAL FORM | ALPHA/BETA BARREL, HELIX SWAPPING, LYASE
3fa3:F (THR271) to (GLY299) CRYSTAL STRUCTURE OF 2,3-DIMETHYLMALATE LYASE, A PEP MUTASE/ISOCITRATE LYASE SUPERFAMILY MEMBER, TRIGONAL CRYSTAL FORM | ALPHA/BETA BARREL, HELIX SWAPPING, LYASE
4xa1:C (THR26) to (TYR247) CRYSTAL STRUCTURE OF THE COILED-COIL SURROUNDING SKIP 1 OF MYH7 | MYOSIN, COILED COIL, SKIP RESIDUE, FUSION, GP7, EB1, MYH7, CARDIAC, MOTOR PROTEIN
3fbv:A (PRO1077) to (SER1115) CRYSTAL STRUCTURE OF THE OLIGOMER FORMED BY THE KINASE-RIBONUCLEASE DOMAIN OF IRE1 | IRE1, RNASE, RIBONUCLEASE, COMPLEX, KINASE, INHIBITOR, OLIGOMER, CYTOPLASMIC, APY29, AMINOPYRAZOLE, ATP-BINDING, ENDOPLASMIC RETICULUM, GLYCOPROTEIN, HYDROLASE, MAGNESIUM, MEMBRANE, METAL- BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UNFOLDED PROTEIN RESPONSE
3fbv:B (PRO1077) to (SER1115) CRYSTAL STRUCTURE OF THE OLIGOMER FORMED BY THE KINASE-RIBONUCLEASE DOMAIN OF IRE1 | IRE1, RNASE, RIBONUCLEASE, COMPLEX, KINASE, INHIBITOR, OLIGOMER, CYTOPLASMIC, APY29, AMINOPYRAZOLE, ATP-BINDING, ENDOPLASMIC RETICULUM, GLYCOPROTEIN, HYDROLASE, MAGNESIUM, MEMBRANE, METAL- BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UNFOLDED PROTEIN RESPONSE
3fbv:D (PRO1077) to (SER1115) CRYSTAL STRUCTURE OF THE OLIGOMER FORMED BY THE KINASE-RIBONUCLEASE DOMAIN OF IRE1 | IRE1, RNASE, RIBONUCLEASE, COMPLEX, KINASE, INHIBITOR, OLIGOMER, CYTOPLASMIC, APY29, AMINOPYRAZOLE, ATP-BINDING, ENDOPLASMIC RETICULUM, GLYCOPROTEIN, HYDROLASE, MAGNESIUM, MEMBRANE, METAL- BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UNFOLDED PROTEIN RESPONSE
3fbv:F (PRO1077) to (SER1115) CRYSTAL STRUCTURE OF THE OLIGOMER FORMED BY THE KINASE-RIBONUCLEASE DOMAIN OF IRE1 | IRE1, RNASE, RIBONUCLEASE, COMPLEX, KINASE, INHIBITOR, OLIGOMER, CYTOPLASMIC, APY29, AMINOPYRAZOLE, ATP-BINDING, ENDOPLASMIC RETICULUM, GLYCOPROTEIN, HYDROLASE, MAGNESIUM, MEMBRANE, METAL- BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UNFOLDED PROTEIN RESPONSE
3fbv:M (PRO1077) to (SER1115) CRYSTAL STRUCTURE OF THE OLIGOMER FORMED BY THE KINASE-RIBONUCLEASE DOMAIN OF IRE1 | IRE1, RNASE, RIBONUCLEASE, COMPLEX, KINASE, INHIBITOR, OLIGOMER, CYTOPLASMIC, APY29, AMINOPYRAZOLE, ATP-BINDING, ENDOPLASMIC RETICULUM, GLYCOPROTEIN, HYDROLASE, MAGNESIUM, MEMBRANE, METAL- BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UNFOLDED PROTEIN RESPONSE
3feg:A (THR305) to (LEU388) CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE BETA IN COMPLEX WITH PHOSPHORYLATED HEMICHOLINIUM-3 AND ADENOSINE NUCLEOTIDE | NON-PROTEIN KINASE, CHOLINE KINASE, STRUCTURAL GENOMICS CONSORTIUM, SGC, HEMICHOLINIUM-3, PHOSPHORYLATION, KINASE, PHOSPHOPROTEIN, TRANSFERASE
3fer:A (THR150) to (PRO194) CRYSTAL STRUCTURE OF N-TERMINAL ACTIN-BINDING DOMAIN FROM HUMAN FILAMIN B (TANDEM CH-DOMAINS). NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR5571A. | X-RAY NESG HR5571A ACTIN-BINDING DOMAIN, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, ACTIN-BINDING, ALTERNATIVE SPLICING, CYTOPLASM, CYTOSKELETON, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, DISEASE MUTATION, DWARFISM, MYOGENESIS, PHOSPHOPROTEIN, POLYMORPHISM, ACTIN BINDING PROTEIN
3sdj:A (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
3sdj:B (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
3sdj:C (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
3sdj:D (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
3sdj:E (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
3sdj:F (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
3sdj:G (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
3sdj:H (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
3sdj:I (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
3sdj:J (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
3sdj:K (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
3sdj:L (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
3sdj:M (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
3sdj:N (PRO1077) to (SER1115) STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1 | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, TRANSFERASE, HYDROLASE
4hzk:B (VAL907) to (VAL952) CRYSTAL STRUCTURE OF FREE CRM1 (CRYSTAL FORM 2) | HEAT REPEAT PROTEIN, NUCLEAR EXPORT RECEPTOR, TRANSPORT PROTEIN
3fgg:B (GLN88) to (LYS142) CRYSTAL STRUCTURE OF PUTATIVE ECF-TYPE SIGMA FACTOR NEGATIVE EFFECTOR FROM BACILLUS CEREUS | ALL ALPHA-STRUCTURE, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
3fie:B (GLY272) to (LYS323) CRYSTAL STRUCTURE OF CLOSTRIDIUM BOTULINUM NEUROTOXIN SEROTYPE F CATALYTIC DOMAIN WITH AN INHIBITOR (INH1) | CLOSTRIDIUM BOTULINUM, BONT F, VAMP, INHIBITOR, COMPLEX STRUCTURE, ACETYLATION, CELL JUNCTION, CRYSTAL STRUCTURE, HYDROLASE, TOXIN/PROTEIN TRANSPORT COMPLEX
2c2v:H (GLN104) to (LEU150) CRYSTAL STRUCTURE OF THE CHIP-UBC13-UEV1A COMPLEX | CHAPERONE, HEAT-SHOCK PROTEIN COMPLEX, E3 LIGASE, UBIQUITINYLATION, TPR, HEAT-SHOCK PROTEIN
2c2v:K (GLN104) to (MET153) CRYSTAL STRUCTURE OF THE CHIP-UBC13-UEV1A COMPLEX | CHAPERONE, HEAT-SHOCK PROTEIN COMPLEX, E3 LIGASE, UBIQUITINYLATION, TPR, HEAT-SHOCK PROTEIN
2pt3:A (GLU196) to (LEU283) CRYSTAL STRUCTURE OF BOVINE LACTOPEROXIDASE AT 2.34 A RESOLUTION REVEALS MULTIPLE ANION BINDING SITES | HEME, ANION BINDING SITES, OXIDOREDUCTASE
3ska:B (SER478) to (PHE526) I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ske:B (SER478) to (ARG523) I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3skh:B (SER478) to (PHE526) I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1oq4:A (LEU278) to (ARG340) THE CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN STEAROYL ACYL CARRIER PROTEIN DESATURASE FROM RICINUS COMMUNIS (CASTOR BEAN) AND AZIDE. | DI-IRON ENZYME, FOUR-HELIX BUNDLE, FATTY ACID BIOSYNTHESIS, ELECTRON TRANSFER, OXIDOREDUCTASE
1oq4:B (LEU278) to (ARG340) THE CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN STEAROYL ACYL CARRIER PROTEIN DESATURASE FROM RICINUS COMMUNIS (CASTOR BEAN) AND AZIDE. | DI-IRON ENZYME, FOUR-HELIX BUNDLE, FATTY ACID BIOSYNTHESIS, ELECTRON TRANSFER, OXIDOREDUCTASE
1oq4:C (LEU278) to (ARG340) THE CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN STEAROYL ACYL CARRIER PROTEIN DESATURASE FROM RICINUS COMMUNIS (CASTOR BEAN) AND AZIDE. | DI-IRON ENZYME, FOUR-HELIX BUNDLE, FATTY ACID BIOSYNTHESIS, ELECTRON TRANSFER, OXIDOREDUCTASE
1oq4:D (LEU278) to (ARG340) THE CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN STEAROYL ACYL CARRIER PROTEIN DESATURASE FROM RICINUS COMMUNIS (CASTOR BEAN) AND AZIDE. | DI-IRON ENZYME, FOUR-HELIX BUNDLE, FATTY ACID BIOSYNTHESIS, ELECTRON TRANSFER, OXIDOREDUCTASE
1oq4:E (LEU278) to (ARG340) THE CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN STEAROYL ACYL CARRIER PROTEIN DESATURASE FROM RICINUS COMMUNIS (CASTOR BEAN) AND AZIDE. | DI-IRON ENZYME, FOUR-HELIX BUNDLE, FATTY ACID BIOSYNTHESIS, ELECTRON TRANSFER, OXIDOREDUCTASE
1oq4:F (LEU278) to (ARG340) THE CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN STEAROYL ACYL CARRIER PROTEIN DESATURASE FROM RICINUS COMMUNIS (CASTOR BEAN) AND AZIDE. | DI-IRON ENZYME, FOUR-HELIX BUNDLE, FATTY ACID BIOSYNTHESIS, ELECTRON TRANSFER, OXIDOREDUCTASE
4i99:B (GLN145) to (SER167) CRYSTAL STRUCTURE OF THE SMCHEAD BOUND TO THE C-WINGED HELIX DOMAIN OF SCPA | WINGED-HELIX DOMAIN AND SMC HEAD DOMAIN, CHROMOSOME CONDENSATION, SCPB, DNA BINDING PROTEIN
2q01:A (PHE68) to (GLY126) CRYSTAL STRUCTURE OF GLUCURONATE ISOMERASE FROM CAULOBACTER CRESCENTUS | ISOMERASE, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
3fqk:A (SER478) to (LYS523) HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH HCV-796 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE, HCV-796
3fqk:B (SER478) to (LYS523) HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH HCV-796 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE, HCV-796
1cmy:C (SER3) to (PHE43) THE MUTATION BETA99 ASP-TYR STABILIZES Y-A NEW, COMPOSITE QUATERNARY STATE OF HUMAN HEMOGLOBIN | OXYGEN TRANSPORT
4xlp:D (GLY457) to (LEU503) CRYSTAL STRUCTURE OF T.AQUATICUS TRANSCRIPTION INITIATION COMPLEX CONTAINING UPSTREAM FORK PROMOTER | PROTEIN-DNA COMPLEX, BACTERIAL TRANSCRIPTION INITIATION COMPLEX, TRANSCRIPTION, TRANSCRIPTION-DNA COMPLEX
4xlp:J (GLY457) to (LEU503) CRYSTAL STRUCTURE OF T.AQUATICUS TRANSCRIPTION INITIATION COMPLEX CONTAINING UPSTREAM FORK PROMOTER | PROTEIN-DNA COMPLEX, BACTERIAL TRANSCRIPTION INITIATION COMPLEX, TRANSCRIPTION, TRANSCRIPTION-DNA COMPLEX
3fs4:C (SER3) to (PHE43) CRYSTAL STRUCTURE DETERMINATION OF OSTRICH HEMOGLOBIN AT 2.2 ANGSTROM RESOLUTION | HEMOGLOBIN, AVIAN SPECIES, OSTRICH, QUATERNARY STRUCTURE, HEME, IRON, METAL-BINDING, OXYGEN TRANSPORT, POLYMORPHISM, TRANSPORT, OXYGEN STORAGE
3fsh:B (VAL116) to (GLY164) CRYSTAL STRUCTURE OF THE UBIQUITIN CONJUGATING ENZYME UBE2G2 BOUND TO THE G2BR DOMAIN OF UBIQUITIN LIGASE GP78 | PROTEIN-PEPTIDE COMPLEX, LIGASE, UBL CONJUGATION PATHWAY, ALTERNATIVE SPLICING, ENDOPLASMIC RETICULUM, MEMBRANE, METAL-BINDING, PHOSPHOPROTEIN, POLYMORPHISM, RECEPTOR, TRANSMEMBRANE, ZINC, ZINC-FINGER
4iaq:A (ALA154) to (LEU227) CRYSTAL STRUCTURE OF THE CHIMERIC PROTEIN OF 5-HT1B-BRIL IN COMPLEX WITH DIHYDROERGOTAMINE (PSI COMMUNITY TARGET) | DIHYDROERGOTAMINE, NOVEL PROTEIN ENGINEERING, GPCR NETWORK, MEMBRANE PROTEIN, PSI-BIOLOGY, STRUCTURAL GENOMICS, GPCR, SIGNALING PROTEIN, ELECTRON TRANSPORT, GPCR DOCK
4xlq:J (ALA458) to (ASP504) CRYSTAL STRUCTURE OF T.AQUATICUS TRANSCRIPTION INITIATION COMPLEX CONTAINING UPSTREAM FORK (-11 BASE-PAIRED) PROMOTER | PROTEIN-DNA COMPLEX, BACTERIAL TRANSCRIPTION INITIATION COMPLEX, TRANSCRIPTION-DNA COMPLEX
2q58:B (SER2301) to (THR2356) CRYPTOSPORIDIUM PARVUM PUTATIVE POLYPRENYL PYROPHOSPHATE SYNTHASE (CGD4_2550) IN COMPLEX WITH ZOLEDRONATE | FARNESYL DIPHOSPHATE SYNTHASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
1cuk:A (PRO83) to (GLY134) ESCHERICHIA COLI RUVA PROTEIN AT PH 4.9 AND ROOM TEMPERATURE | DNA REPAIR, SOS RESPONSE, DNA-BINDING, DNA RECOMBINATION, HELICASE
4xls:J (ALA458) to (GLY506) CRYSTAL STRUCTURE OF T. AQUATICUS TRANSCRIPTION INITIATION COMPLEX WITH CARD CONTAINING UPSTREAM FORK PROMOTER. | PROTEIN-DNA COMPLEX, BACTERIAL TRANSCRIPTION INITIATION COMPLEX, TRANSCRIPTION
3fwx:B (LEU126) to (LYS163) THE CRYSTAL STRUCTURE OF THE PEPTIDE DEFORMYLASE FROM VIBRIO CHOLERAE O1 BIOVAR EL TOR STR. N16961 | PEPTIDE DEFORMYLASE, STRUCTURAL GENOMICS, CSGID, HYDROLASE, NIAID STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES
2cbi:A (PRO544) to (SER599) STRUCTURE OF THE CLOSTRIDIUM PERFRINGENS NAGJ FAMILY 84 GLYCOSIDE HYDROLASE, A HOMOLOGUE OF HUMAN O-GLCNACASE | O-GLCNAC, FAMILY 84 GLYCOSIDE HYDROLASES, GLYCOSIDE HYDROLASE, HYALURONIDASES, CARBOHYDRATES, HYDROLASE
4ih6:A (SER478) to (LYS523) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS | FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ih6:B (SER478) to (LYS523) HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS | FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2q9n:A (GLY98) to (GLY167) 4-SUBSTITUTED TRINEMS AS BROAD SPECTRUM-LACTAMASE INHIBITORS: STRUCTURE-BASED DESIGN, SYNTHESIS AND BIOLOGICAL ACTIVITY | BETA-LACTAMASE INHIBITOR, TRICYCLIC CARBAPENEM, HYDROLASE
3g15:B (THR371) to (LEU455) CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE ALPHA IN COMPLEX WITH HEMICHOLINIUM-3 AND ADP | NON-PROTEIN KINASE, CHOLINE KINASE, STRUCTURAL GENOMICS CONSORTIUM, SGC, HEMICHOLINIUM-3, KINASE, TRANSFERASE
2cfw:A (SER288) to (ALA308) AGAO IN COMPLEX WITH WC7A (RU-WIRE INHIBITOR, 7-CARBON LINKER, DATA SET A) | AMINE OXIDASE, ARTHROBACTER GLOBIFORMIS, COPPER CONTAINING, OXIDOREDUCTASE, TPQ, CUAO, QUINONE, RUTHENIUM DIIMINE WIRES, COMPETITIVE INHIBITION, METAL-BINDING
3syp:A (TYR76) to (ALA117) CRYSTAL STRUCTURE OF THE G PROTEIN-GATED INWARD RECTIFIER K+ CHANNEL GIRK2 (KIR3.2) R201A MUTANT | ION CHANNEL, POTASSIUM CHANNEL, INWARD RECTIFICATION, SODIUM BINDING, PIP2 BINDING, G PROTEIN BINDING, METAL TRANSPORT
2cg1:A (SER288) to (ALA308) AGAO IN COMPLEX WITH WC11B (RU-WIRE INHIBITOR, 11-CARBON LINKER, DATA SET B) | AMINE OXIDASE, ARTHROBACTER GLOBIFORMIS, COPPER, COPPER CONTAINING, OXIDOREDUCTASE, TPQ, CUAO, QUINONE, RUTHENIUM DIIMINE WIRES, COMPETITIVE INHIBITION, METAL-BINDING
1p7g:B (LEU30) to (ASN96) CRYSTAL STRUCTURE OF SUPEROXIDE DISMUTASE FROM PYROBACULUM AEROPHILUM | ALPHA-BETA, OXIDOREDUCTASE
1p7g:C (LEU30) to (ASN96) CRYSTAL STRUCTURE OF SUPEROXIDE DISMUTASE FROM PYROBACULUM AEROPHILUM | ALPHA-BETA, OXIDOREDUCTASE
1p7g:G (LEU30) to (ASN96) CRYSTAL STRUCTURE OF SUPEROXIDE DISMUTASE FROM PYROBACULUM AEROPHILUM | ALPHA-BETA, OXIDOREDUCTASE
1p7g:I (LEU30) to (ASN96) CRYSTAL STRUCTURE OF SUPEROXIDE DISMUTASE FROM PYROBACULUM AEROPHILUM | ALPHA-BETA, OXIDOREDUCTASE
1p7g:K (LEU30) to (ASN96) CRYSTAL STRUCTURE OF SUPEROXIDE DISMUTASE FROM PYROBACULUM AEROPHILUM | ALPHA-BETA, OXIDOREDUCTASE
1p7g:M (LEU30) to (ASN96) CRYSTAL STRUCTURE OF SUPEROXIDE DISMUTASE FROM PYROBACULUM AEROPHILUM | ALPHA-BETA, OXIDOREDUCTASE
1p7g:N (LEU30) to (ASN96) CRYSTAL STRUCTURE OF SUPEROXIDE DISMUTASE FROM PYROBACULUM AEROPHILUM | ALPHA-BETA, OXIDOREDUCTASE
1p7g:O (LEU30) to (ASN96) CRYSTAL STRUCTURE OF SUPEROXIDE DISMUTASE FROM PYROBACULUM AEROPHILUM | ALPHA-BETA, OXIDOREDUCTASE
1p7g:S (LEU30) to (ASN96) CRYSTAL STRUCTURE OF SUPEROXIDE DISMUTASE FROM PYROBACULUM AEROPHILUM | ALPHA-BETA, OXIDOREDUCTASE
1p7g:U (LEU30) to (ASN96) CRYSTAL STRUCTURE OF SUPEROXIDE DISMUTASE FROM PYROBACULUM AEROPHILUM | ALPHA-BETA, OXIDOREDUCTASE
2qe2:A (SER478) to (LYS523) STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR | TRANSFERASE
2qe2:B (SER478) to (LYS523) STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR | TRANSFERASE
2qe5:A (SER478) to (TYR524) STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR | TRANSFERASE POLYMERASE
2qe5:B (SER478) to (LYS523) STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR | TRANSFERASE POLYMERASE
2qfo:A (TYR38) to (GLY73) HSP90 COMPLEXED WITH A143571 AND A516383 | PROTEIN-INHIBITOR COMPLEX, ATP-BINDING, CHAPERONE, NUCLEOTIDE- BINDING, PHOSPHOPROTEIN, STRESS RESPONSE
4il1:A (ASP173) to (ASN209) CRYSTAL STRUCTURE OF THE RAT CALCINEURIN | HYDROLASE, CALCIUM-BINDING PROTEIN, CHIMERA PROTEIN, FUSION PROTEIN, PROTEIN PHOSPHATASE,
4il1:C (ASP173) to (ASN209) CRYSTAL STRUCTURE OF THE RAT CALCINEURIN | HYDROLASE, CALCIUM-BINDING PROTEIN, CHIMERA PROTEIN, FUSION PROTEIN, PROTEIN PHOSPHATASE,
4il1:D (ASP173) to (ASN209) CRYSTAL STRUCTURE OF THE RAT CALCINEURIN | HYDROLASE, CALCIUM-BINDING PROTEIN, CHIMERA PROTEIN, FUSION PROTEIN, PROTEIN PHOSPHATASE,
2qfz:A (ALA353) to (GLU411) CRYSTAL STRUCTURE OF HUMAN TBC1 DOMAIN FAMILY MEMBER 22A | RAB-GAP, GTPASE ACTIVATOR, TBC1, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, HYDROLASE ACTIVATOR
2qg0:B (TYR38) to (GLY73) HSP90 COMPLEXED WITH A943037 | PROTEIN-INHIBITOR COMPLEX, CHAPERONE
4xrk:A (TYR255) to (VAL307) CRYSTAL STRUCTURE OF IMPORTIN BETA IN A POLYETHYLENE GLYCOL CONDITION | TRANSPORT PROTEIN, NUCLEAR TRANSPORT, TRANSPORT RECEPTOR, IMPORTIN- BETA SUPERFAMILY, HEAT REPEAT PROTEIN, NUCLEAR IMPORT OF VARIOUS PROTEINACEOUS CARGO MOLECULES, HIGHLY FLEXIBLE PROTEINS
4ima:A (GLY21) to (LEU44) THE STRUCTURE OF C436M-HLPYK IN COMPLEX WITH CITRATE/MN/ATP/FRU-1,6-BP | HUMAN LIVER PYRUVATE KINASE, OXIDIZABLE CYSTEINE, PHOSPHORYLATION, PHOSPHOENOLPYRUVATE, PEP, TRANSFERASE
4ima:B (GLY21) to (LEU44) THE STRUCTURE OF C436M-HLPYK IN COMPLEX WITH CITRATE/MN/ATP/FRU-1,6-BP | HUMAN LIVER PYRUVATE KINASE, OXIDIZABLE CYSTEINE, PHOSPHORYLATION, PHOSPHOENOLPYRUVATE, PEP, TRANSFERASE
4ima:C (GLY21) to (LEU44) THE STRUCTURE OF C436M-HLPYK IN COMPLEX WITH CITRATE/MN/ATP/FRU-1,6-BP | HUMAN LIVER PYRUVATE KINASE, OXIDIZABLE CYSTEINE, PHOSPHORYLATION, PHOSPHOENOLPYRUVATE, PEP, TRANSFERASE
3g61:A (VAL33) to (ILE123) STRUCTURE OF P-GLYCOPROTEIN REVEALS A MOLECULAR BASIS FOR POLY- SPECIFIC DRUG BINDING | P-GLYCOPROTEIN, PGP, MULTIDRUG RESISTANCE, MEMBRANE PROTEIN, CYCLE PEPTIDES, ATP-BINDING, NUCLEOTIDE-BINDING
2cko:A (THR371) to (LEU455) CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE ALPHA 2 | KINASE, TRANSFERASE, CHOLINE KINASE, PHOSPHATYDILCHOLINE, ALTERNATIVE SPLICING
2ckq:A (THR371) to (LEU455) CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE ALPHA 2 IN COMPLEX WITH PHOSPHOCHOLINE | TRANSFERASE, PHOSPHATIDYLCHOLINE, PHOSPHOLIPID SYNTHESIS
2ckq:B (THR371) to (GLY456) CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE ALPHA 2 IN COMPLEX WITH PHOSPHOCHOLINE | TRANSFERASE, PHOSPHATIDYLCHOLINE, PHOSPHOLIPID SYNTHESIS
4xsx:D (ALA182) to (SER230) CRYSTAL STRUCTURE OF CBR 703 BOUND TO ESCHERICHIA COLI RNA POLYMERASE HOLOENZYME | BACTERIAL RNA POLYMERASE ANTIBIOTIC COMPLEX, TRANSCRIPTION-ANTIBIOTIC COMPLEX
4xsx:J (ALA182) to (SER230) CRYSTAL STRUCTURE OF CBR 703 BOUND TO ESCHERICHIA COLI RNA POLYMERASE HOLOENZYME | BACTERIAL RNA POLYMERASE ANTIBIOTIC COMPLEX, TRANSCRIPTION-ANTIBIOTIC COMPLEX
3g86:A (SER478) to (LYS523) HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH THIAZINE INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3- BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3g86:B (SER478) to (LYS523) HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH THIAZINE INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3- BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
4xsy:D (ALA182) to (SER230) CRYSTAL STRUCTURE OF CBR 9379 BOUND TO ESCHERICHIA COLI RNA POLYMERASE HOLOENZYME | BACTERIAL RNA POLYMERASE ANTIBIOTIC COMPLEX, TRANSCRIPTION-ANTIBIOTIC COMPLEX
4xsy:J (ALA182) to (SER230) CRYSTAL STRUCTURE OF CBR 9379 BOUND TO ESCHERICHIA COLI RNA POLYMERASE HOLOENZYME | BACTERIAL RNA POLYMERASE ANTIBIOTIC COMPLEX, TRANSCRIPTION-ANTIBIOTIC COMPLEX
2cqz:A (LEU69) to (CYS112) CRYSTAL STRUCTURE OF PH0347 PROTEIN FROM PYROCOCCUS HORIKOSHII OT3 | HYPOTHETICAL PROTEINS, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, UNKNOWN FUNCTION
2cqz:B (LEU69) to (CYS112) CRYSTAL STRUCTURE OF PH0347 PROTEIN FROM PYROCOCCUS HORIKOSHII OT3 | HYPOTHETICAL PROTEINS, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, UNKNOWN FUNCTION
2cqz:C (LEU69) to (CYS112) CRYSTAL STRUCTURE OF PH0347 PROTEIN FROM PYROCOCCUS HORIKOSHII OT3 | HYPOTHETICAL PROTEINS, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, UNKNOWN FUNCTION
2cqz:D (LEU69) to (CYS112) CRYSTAL STRUCTURE OF PH0347 PROTEIN FROM PYROCOCCUS HORIKOSHII OT3 | HYPOTHETICAL PROTEINS, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, UNKNOWN FUNCTION
2cqz:E (LEU69) to (CYS112) CRYSTAL STRUCTURE OF PH0347 PROTEIN FROM PYROCOCCUS HORIKOSHII OT3 | HYPOTHETICAL PROTEINS, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, UNKNOWN FUNCTION
2cqz:F (LEU69) to (CYS112) CRYSTAL STRUCTURE OF PH0347 PROTEIN FROM PYROCOCCUS HORIKOSHII OT3 | HYPOTHETICAL PROTEINS, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, UNKNOWN FUNCTION
1piu:A (GLU260) to (ASN300) OXIDIZED RIBONUCLEOTIDE REDUCTASE R2-D84E MUTANT CONTAINING OXO-BRIDGED DIFERRIC CLUSTER | FOUR-HELIX BUNDLE, OXO-BRIDGED DIFERRIC CLUSTER, OXIDOREDUCTASE
2cw0:N (GLY457) to (ASP504) CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS RNA POLYMERASE HOLOENZYME AT 3.3 ANGSTROMS RESOLUTION | RNA POLYMERASE HOLOENZYME, TRANSCRIPTION, BENT-BRIDGE HELIX, TRANSFERASE
2qrw:G (SER4) to (VAL35) CRYSTAL STUCTURE OF MYCOBACTERIUM TUBERCULOSIS TRHBO WG8F MUTANT | TRUNCATED HEMOGLOBIN FOLD, ALPHA HELIX, HEME, HYDROXYLATION, IRON, MEMBRANE, METAL-BINDING, OXYGEN TRANSPORT, TRANSPORT, TRANSPORT PROTEIN
3t66:A (HIS403) to (GLU447) CRYSTAL STRUCTURE OF NICKEL ABC TRANSPORTER FROM BACILLUS HALODURANS | STRUCTURAL GENOMICS, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, PERIPLASMIC PROTEIN, NICKEL ABC TRANSPORTER, TRANSPORT PROTEIN
2qss:C (SER3) to (PHE43) BOVINE HEMOGLOBIN AT PH 6.3 | HEMOGLOBIN, HEME, IRON, METAL-BINDING, OXYGEN TRANSPORT, TRANSPORT, OXYGEN BINDING
1dtz:A (ASP315) to (ALA343) STRUCTURE OF CAMEL APO-LACTOFERRIN DEMONSTRATES ITS DUAL ROLE IN SEQUESTERING AND TRANSPORTING FERRIC IONS SIMULTANEOUSLY:CRYSTAL STRUCTURE OF CAMEL APO-LACTOFERRIN AT 2.6A RESOLUTION. | CAMEL,LACTOFERRIN,APOLACTOFERRIN,TRANSFERRIN,MILK PROTEIN, METAL TRANSPORT
3t8j:A (PRO186) to (SER216) STRUCTURAL ANALYSIS OF THERMOSTABLE S. SOLFATARICUS PYRIMIDINE- SPECIFIC NUCLEOSIDE HYDROLASE | NUCLEOSIDE HYDROLASE, THERMOSTABLE PROTEIN, OPEN (ALPHA,BETA) STRUCTURE, ROSSMANN FOLD, NH-FOLD, NUCLEOTIDE METABOLISM, N- GLYCOSIDASE, HYDROLASE
3gkv:B (THR4) to (HIS41) X-RAY STRUCTURE OF AN INTERMEDIATE ALONG THE OXIDATION PATHWAY OF TREMATOMUS BERNACCHII HEMOGLOBIN | HEMOGLOBIN, INTERMEDIATE QUATERNARY STRUCTURE,, ACETYLATION, HEME, IRON, METAL-BINDING, OXYGEN TRANSPORT, TRANSPORT
4y04:A (ALA334) to (ALA388) CRYSTAL STRUCTURE OF DIPEPTIDYL PEPTIDASE 11 (DPP11) FROM PORPHYROMONAS GINGIVALIS (SPACE) | SPACE, WT, HYDROLASE
2qva:C (ARG117) to (ARG183) CRYSTAL STRUCTURE OF DROSOPHILA MELANOGASTER TRANSLIN PROTEIN | TRANSLIN, CRYSTAL STRUCTURE, D. MELANOGASTER, DNA BINDING PROTEIN
4iz0:A (SER478) to (TYR524) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2,4,5- TRICHLORO-N-(5-METHYL-1,2-OXAZOL-3-YL)BENZENESULFONAMIDE | HCV NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4iz0:B (SER478) to (PHE526) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2,4,5- TRICHLORO-N-(5-METHYL-1,2-OXAZOL-3-YL)BENZENESULFONAMIDE | HCV NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j02:A (SER478) to (ARG523) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH [(1R)-5,8- DICHLORO-1-PROPYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOL-1-YL]ACETIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j02:B (SER478) to (PHE526) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH [(1R)-5,8- DICHLORO-1-PROPYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOL-1-YL]ACETIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j04:A (SER478) to (ASN527) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 4-CHLORO-2- {[(2,4,5-TRICHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j04:B (SER478) to (PHE526) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 4-CHLORO-2- {[(2,4,5-TRICHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j06:A (SER478) to (ASN527) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(5- BROMOTHIOPHEN-2-YL)SULFONYL]AMINO}-4-CHLOROBENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j06:B (SER478) to (PHE526) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(5- BROMOTHIOPHEN-2-YL)SULFONYL]AMINO}-4-CHLOROBENZOIC ACID | RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3gnv:A (SER478) to (TYR524) HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 1B | HEPATITIS C VIRUS, 1.5-BENZODIAZEPINE, NS5B, SULFONE, POLYMERASE, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3gnv:B (SER478) to (ARG523) HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 1B | HEPATITIS C VIRUS, 1.5-BENZODIAZEPINE, NS5B, SULFONE, POLYMERASE, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3gnw:A (SER478) to (ARG523) HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 4C | 1,5-BENZODIAZEPINES, HEPATITIS C VIRUS, NS5B, POLYMERASE, SULFONE, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3gou:C (SER3) to (PHE43) CRYSTAL STRUCTURE OF DOG (CANIS FAMILIARIS) HEMOGLOBIN | HEME, OXYGEN TRANSPORT, TETRAMER, IRON, METAL-BINDING, POLYMORPHISM, TRANSPORT
2r02:A (PRO360) to (GLN427) CRYSTAL STRUCTURE OF ALIX/AIP1 IN COMPLEX WITH THE HIV-1 YPLTSL LATE DOMAIN | PEPTIDE, COILED-COIL, APOPTOSIS, CYTOPLASM, HOST-VIRUS INTERACTION, POLYMORPHISM, PROTEIN TRANSPORT, TRANSPORT, AIDS, CAPSID PROTEIN, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MYRISTATE, NUCLEUS, PHOSPHORYLATION, RNA-BINDING, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER
1e3u:A (GLU129) to (VAL193) MAD STRUCTURE OF OXA10 CLASS D BETA-LACTAMASE | BETA-LACTAMASE, ANTIOBITIC RESISTANCE
1e3u:B (GLU129) to (VAL193) MAD STRUCTURE OF OXA10 CLASS D BETA-LACTAMASE | BETA-LACTAMASE, ANTIOBITIC RESISTANCE
1e3u:C (GLY128) to (VAL193) MAD STRUCTURE OF OXA10 CLASS D BETA-LACTAMASE | BETA-LACTAMASE, ANTIOBITIC RESISTANCE
1e3u:D (GLY128) to (VAL193) MAD STRUCTURE OF OXA10 CLASS D BETA-LACTAMASE | BETA-LACTAMASE, ANTIOBITIC RESISTANCE
1e4d:B (GLU129) to (VAL193) STRUCTURE OF OXA10 BETA-LACTAMASE AT PH 8.3 | BETA-LACTAMASE, ANTIOBITIC RESISTANCE
1e4d:C (GLU129) to (VAL193) STRUCTURE OF OXA10 BETA-LACTAMASE AT PH 8.3 | BETA-LACTAMASE, ANTIOBITIC RESISTANCE
4y55:A (PRO197) to (LEU283) CRYSTAL STRUCTURE OF BUFFALO LACTOPEROXIDASE WITH RHODANIDE AT 2.09 ANGSTROM RESOLUTION | LACTOPEROXIDASE, OXIDOREDUCTASE, SUBSTRATE
2r4e:B (GLY52) to (PHE83) CRYSTAL STRUCTURE OF ESCHERICHIA COLI GLYCEROL-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH DHAP | GLPD, CYTOPLASM, FAD, FLAVOPROTEIN, GLYCEROL METABOLISM, OXIDOREDUCTASE
3gsz:A (SER478) to (TYR524) STRUCTURE OF THE GENOTYPE 2B HCV POLYMERASE | POLYMERASE, HCV, TRANSFERASE
3gsz:B (SER478) to (ALA529) STRUCTURE OF THE GENOTYPE 2B HCV POLYMERASE | POLYMERASE, HCV, TRANSFERASE
1q1t:C (ASP217) to (ILE252) MOUSE IMPORTIN ALPHA: NON-PHOSPHORYLATED SV40 CN PEPTIDE COMPLEX | IMPORTIN ALPHA/KARYOPHERIN ALPHA, NUCLEAR LOCALISATION SEQUENCE (NLS) RECOGNITION, PHOSPHORYLATION, SIMIAN VIRUS (SV40) LARGE TUMOR-ANTIGEN (T-ANTIGEN) NLS, X-RAY CRYSTAL STRUCTURE, PROTEIN TRANSPORT
3tgy:A (PRO197) to (LEU283) CRYSTAL STRUCTURE OF THE COMPLEX OF BOVINE LACTOPEROXIDASE WITH ASCORBIC ACID AT 2.35 A RESOLUTION | LACTOPEROXIDASE, ASCORBIC ACID, GLYCOPROTEIN, HEME MOIETY, FERRIC IRON, OXIDOREDUCTASE
1ebo:A (GLN3) to (ARG108) CRYSTAL STRUCTURE OF THE EBOLA VIRUS MEMBRANE-FUSION SUBUNIT, GP2, FROM THE ENVELOPE GLYCOPROTEIN ECTODOMAIN | MEMBRANE FUSION SUBUNIT, VIRAL PROTEIN
4jc5:B (VAL154) to (ALA192) IMMUNE ACTIVATOR BOUND TO RECEPTOR | INNATE IMMUNE RECEPTOR, IMMUNE SYSTEM
2dqb:A (HIS117) to (ALA167) CRYSTAL STRUCTURE OF DNTP TRIPHOSPHOHYDROLASE FROM THERMUS THERMOPHILUS HB8, WHICH IS HOMOLOGOUS TO DGTP TRIPHOSPHOHYDROLASE | DNTPASE, DNTP, TRIPHOSPHOHYDROLASE, SINGLE-STRANDED DNA, DNA, DGTPASE, HD SUPERFAMILY, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, HYDROLASE, DNA BINDING PROTEIN
2dqb:C (GLY116) to (THR168) CRYSTAL STRUCTURE OF DNTP TRIPHOSPHOHYDROLASE FROM THERMUS THERMOPHILUS HB8, WHICH IS HOMOLOGOUS TO DGTP TRIPHOSPHOHYDROLASE | DNTPASE, DNTP, TRIPHOSPHOHYDROLASE, SINGLE-STRANDED DNA, DNA, DGTPASE, HD SUPERFAMILY, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, HYDROLASE, DNA BINDING PROTEIN
2dqb:C (ILE346) to (LEU374) CRYSTAL STRUCTURE OF DNTP TRIPHOSPHOHYDROLASE FROM THERMUS THERMOPHILUS HB8, WHICH IS HOMOLOGOUS TO DGTP TRIPHOSPHOHYDROLASE | DNTPASE, DNTP, TRIPHOSPHOHYDROLASE, SINGLE-STRANDED DNA, DNA, DGTPASE, HD SUPERFAMILY, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, HYDROLASE, DNA BINDING PROTEIN
1q8f:B (GLY188) to (ASN230) CRYSTAL STRUCTURE OF THE E.COLI PYRIMIDINE NUCLEOSIDE HYDROLASE YEIK | OPEN ALPHA-BETA STRUCTURE, NH-FOLD, HYDROLASE
1q8f:C (GLY188) to (ASN230) CRYSTAL STRUCTURE OF THE E.COLI PYRIMIDINE NUCLEOSIDE HYDROLASE YEIK | OPEN ALPHA-BETA STRUCTURE, NH-FOLD, HYDROLASE
3to5:A (MET63) to (PRO85) HIGH RESOLUTION STRUCTURE OF CHEY3 FROM VIBRIO CHOLERAE | ALPHA(5)BETA(5), CHEMOTAXIS, FLIM, PHOSPHORYLATION, MOTOR ACTION, SIGNALING PROTEIN
3gyn:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL MONOCYCLIC DIHYDROPYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION REGULATION, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
2rcv:F (LEU15) to (SER53) CRYSTAL STRUCTURE OF THE BACILLUS SUBTILIS SUPEROXIDE DISMUTASE | BACILLUS SUBTILIS,SUPEROXIDE DISMUTASE, MANGANESE, METAL- BINDING, OXIDOREDUCTASE, PHOSPHORYLATION, STRESS RESPONSE
4ydh:A (SER211) to (HIS250) THE STRUCTURE OF HUMAN FMNL1 N-TERMINAL DOMAINS BOUND TO CDC42 | ACTIN CYTOSKELETON, GTPASE, FORMIN, SIGNALING PROTEIN
2rha:A (SER88) to (TYR133) CRYSTAL STRUCTURE OF A PREDICTED DNA-BINDING TRANSCRIPTIONAL REGULATOR (SARO_1072) FROM NOVOSPHINGOBIUM AROMATICIVORANS DSM AT 2.10 A RESOLUTION | TRANSCRIPTION REGULATOR, DNA/RNA-BINDING 3-HELICAL BUNDLE FOLD, HELIX TURN HELIX MOTIF, HTH MOTIF, TRANSCRIPTION REGULATION, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, TRANSCRIPTION
2rio:A (ASP397) to (SER434) STRUCTURE OF THE DUAL ENZYME IRE1 REVEALS THE BASIS FOR CATALYSIS AND REGULATION OF NON-CONVENTIONAL SPLICING | PROTEIN-NUCLEOTIDE COMPLEX, ATP-BINDING, ENDOPLASMIC RETICULUM, GLYCOPROTEIN, HYDROLASE, KINASE, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE- BINDING, PHOSPHORYLATION, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UNFOLDED PROTEIN RESPONSE
2rio:B (ASP397) to (SER434) STRUCTURE OF THE DUAL ENZYME IRE1 REVEALS THE BASIS FOR CATALYSIS AND REGULATION OF NON-CONVENTIONAL SPLICING | PROTEIN-NUCLEOTIDE COMPLEX, ATP-BINDING, ENDOPLASMIC RETICULUM, GLYCOPROTEIN, HYDROLASE, KINASE, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE- BINDING, PHOSPHORYLATION, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UNFOLDED PROTEIN RESPONSE
4yfn:D (ALA184) to (SER230) ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH SQUARAMIDE COMPOUND 14 (N-[3,4-DIOXO-2-(4-{[4-(TRIFLUOROMETHYL)BENZYL]AMINO}PIPERIDIN-1-YL) CYCLOBUT-1-EN-1-YL]-3,5-DIMETHYL-1,2-OXAZOLE-4-SULFONAMIDE) | SWITCH REGION, SQUARAMIDE, TRANSCRIPTION-TRANSCRIPTION INHIBITOR COMPLEX
2rl3:A (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 W154H MUTANT AT PH 7 | OXA-10, CARBOXYLATED LYSINE, CLASS D BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, HYDROLASE
4jlx:A (LEU139) to (VAL181) STRUCTURE OF PORCINE CYCLIC GMP-AMP SYNTHASE (CGAS) | DNA BINDING PROTEIN
4jlz:A (LEU139) to (VAL181) STRUCTURE OF PORCINE CGAS IN COMPLEX WITH BOUND UTP | DNA BINDING PROTEIN
3tv7:B (THR9) to (LEU69) HUMAN RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH RKI1342 | KINASE, DIMER, DIMERIZATION, MYOSIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3tv7:D (THR9) to (TYR59) HUMAN RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH RKI1342 | KINASE, DIMER, DIMERIZATION, MYOSIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h2l:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH A NOVEL BICYCLIC DIHYDRO-PYRIDINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, HEPATITIS C, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING
2rr7:A (GLY1) to (CYS49) MICROTUBULE BINDING DOMAIN OF DYNEIN-C | DYNEIN, MICROTUBULE-BINDING, STALK HEAD, MTBD, ANTIPARALLEL COILED COIL, MOTOR PROTEIN, DSH
1ewz:A (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA | ALPHA/BETA STRUCTURE, HYDROLASE
1ewz:B (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA | ALPHA/BETA STRUCTURE, HYDROLASE
1ewz:C (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA | ALPHA/BETA STRUCTURE, HYDROLASE
1ewz:D (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA | ALPHA/BETA STRUCTURE, HYDROLASE
1qnm:A (LEU14) to (ASN80) HUMAN MANGANESE SUPEROXIDE DISMUTASE MUTANT Q143N | OXIDOREDUCTASE, MANGANESE SUPEROXIDE DISMUTASE, HMNSOD
1ezr:A (GLY190) to (TYR229) CRYSTAL STRUCTURE OF NUCLEOSIDE HYDROLASE FROM LEISHMANIA MAJOR | ALPHA/BETA FOLD, HYDROLASE
3tyv:A (SER478) to (ARG523) SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3tyv:B (SER478) to (ARG523) SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1f3w:A (TYR369) to (CYS422) RECOMBINANT RABBIT MUSCLE PYRUVATE KINASE | PYRUVATE KINASE, RECOMBINANT, MUSCLE ISOZYME, TRANSFERASE
1f3w:B (TYR369) to (CYS422) RECOMBINANT RABBIT MUSCLE PYRUVATE KINASE | PYRUVATE KINASE, RECOMBINANT, MUSCLE ISOZYME, TRANSFERASE
1f3w:C (TYR369) to (CYS422) RECOMBINANT RABBIT MUSCLE PYRUVATE KINASE | PYRUVATE KINASE, RECOMBINANT, MUSCLE ISOZYME, TRANSFERASE
1f3w:D (TYR369) to (CYS422) RECOMBINANT RABBIT MUSCLE PYRUVATE KINASE | PYRUVATE KINASE, RECOMBINANT, MUSCLE ISOZYME, TRANSFERASE
1f3w:E (TYR369) to (CYS422) RECOMBINANT RABBIT MUSCLE PYRUVATE KINASE | PYRUVATE KINASE, RECOMBINANT, MUSCLE ISOZYME, TRANSFERASE
1f3w:F (TYR369) to (CYS422) RECOMBINANT RABBIT MUSCLE PYRUVATE KINASE | PYRUVATE KINASE, RECOMBINANT, MUSCLE ISOZYME, TRANSFERASE
1f3w:G (TYR369) to (CYS422) RECOMBINANT RABBIT MUSCLE PYRUVATE KINASE | PYRUVATE KINASE, RECOMBINANT, MUSCLE ISOZYME, TRANSFERASE
1f3w:H (TYR369) to (CYS422) RECOMBINANT RABBIT MUSCLE PYRUVATE KINASE | PYRUVATE KINASE, RECOMBINANT, MUSCLE ISOZYME, TRANSFERASE
4ykr:A (TYR38) to (GLY73) HEAT SHOCK PROTEIN 90 BOUND TO CS302 | CHAPERONE, PROTEIN-INHIBITOR COMPLEX, HSP 90, CHAPERONE-INHIBITOR COMPLEX
4ykq:A (TYR38) to (GLY73) HEAT SHOCK PROTEIN 90 BOUND TO CS301 | CHAPERONE, HSP 90, PROTEIN-INHIBITOR COMPLEX, CHAPERONE-INHIBITOR COMPLEX
4ykx:A (TYR38) to (GLY73) HEAT SHOCK PROTEIN 90 BOUND TO CS318 | CHAPERONE, PROTEIN-INHIBITOR COMPLEX, HSP 90, CHAPERONE-INHIBITOR COMPLEX
1f3x:E (TYR369) to (LYS421) S402P MUTANT OF RABBIT MUSCLE PYRUVATE KINASE | PYRUVATE KINASE, S402P, MUSCLE ISOZYME, TRANSFERASE
1f3x:F (TYR369) to (LYS421) S402P MUTANT OF RABBIT MUSCLE PYRUVATE KINASE | PYRUVATE KINASE, S402P, MUSCLE ISOZYME, TRANSFERASE
2e84:A (ASP400) to (ARG428) CRYSTAL STRUCTURE OF HIGH-MOLECULAR WEIGHT CYTOCHROME C FROM DESULFOVIBRIO VULGARIS (MIYAZAKI F) IN THE PRESENCE OF ZINC ION | CYTOCHROME C3 MOTIFS, ELECTRON TRANSPORT
1quv:A (SER478) to (VAL530) CRYSTAL STRUCTURE OF THE RNA DIRECTED RNA POLYMERASE OF HEPATITIS C VIRUS | RNA DEPENDENT RNA POLYMERASE, REPLICASE, HCV, NS5B, TRANSFERASE
3h8d:C (LEU1225) to (LEU1264) CRYSTAL STRUCTURE OF MYOSIN VI IN COMPLEX WITH DAB2 PEPTIDE | MYOSIN VI, MYOSIN 6, DAB2, CARGO BINDING, PROTEIN-PEPTIDE COMPLEX, ACTIN-BINDING, ATP-BINDING, CALMODULIN-BINDING, CELL PROJECTION, COATED PIT, COILED COIL, CYTOPLASM, CYTOPLASMIC VESICLE, DEAFNESS, DISEASE MUTATION, ENDOCYTOSIS, GOLGI APPARATUS, HEARING, MEMBRANE, MOTOR PROTEIN, MYOSIN, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTEIN TRANSPORT, TRANSPORT, ALTERNATIVE SPLICING, MOTOR PROTEIN/SIGNALING PROTEIN COMPLEX
3h98:A (SER478) to (ALA529) CRYSTAL STRUCTURE OF HCV NS5B 1B WITH (1,1-DIOXO-2H-[1,2, 4]BENZOTHIADIAZIN-3-YL) AZOLO[1,5-A]PYRIMIDINE DERIVATIVE | RNA POLYMERASE, NUCLEOTIDE BINDING, TRANSFERASE
3h98:B (SER478) to (PHE526) CRYSTAL STRUCTURE OF HCV NS5B 1B WITH (1,1-DIOXO-2H-[1,2, 4]BENZOTHIADIAZIN-3-YL) AZOLO[1,5-A]PYRIMIDINE DERIVATIVE | RNA POLYMERASE, NUCLEOTIDE BINDING, TRANSFERASE
3ha4:B (SER124) to (MET180) CRYSTAL STRUCTURE OF THE TYPE ONE MEMBRANE PROTEIN MIX1 FROM LEISHMANIA | TPR-LIKE, HELIX-TURN-HELIX, UNKNOWN FUNCTION
3ha4:D (SER124) to (LEU177) CRYSTAL STRUCTURE OF THE TYPE ONE MEMBRANE PROTEIN MIX1 FROM LEISHMANIA | TPR-LIKE, HELIX-TURN-HELIX, UNKNOWN FUNCTION
3ha4:F (SER124) to (MET180) CRYSTAL STRUCTURE OF THE TYPE ONE MEMBRANE PROTEIN MIX1 FROM LEISHMANIA | TPR-LIKE, HELIX-TURN-HELIX, UNKNOWN FUNCTION
1f76:B (PRO4) to (VAL38) ESCHERICHIA COLI DIHYDROOROTATE DEHYDROGENASE | MONOMER, ALPHA-BETA-BARREL, FMN BINDING DOMAIN, OROTATE COMPLEX, OXIDOREDUCTASE
3u4r:B (SER478) to (ARG523) NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE C2 ACYL SULFONAMIDES | NUCLEOTIDYL TRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2efx:F (TYR169) to (MET273) THE CRYSTAL STRUCTURE OF D-AMINO ACID AMIDASE FROM OCHROBACTRUM ANTHROPI SV3 COMPLEXED WITH L-PHENYLALANINE AMIDE | PENICILLIN RECOGNIZING PROTEINS, D-STEREOSPECIFIC AMIDASE, L-PHENYLALANINE AMIDE, HYDROLASE
3hcb:A (ALA24) to (PRO50) CRYSTAL STRUCTURE OF HPNMT IN COMPLEX WITH NORADRENOCHROME AND ADOHCY | METHYLTRANSFERASE, CATECHOLAMINE BIOSYNTHESIS, POLYMORPHISM, S-ADENOSYL-L-METHIONINE, TRANSFERASE
3hcc:A (VAL23) to (PRO50) CRYSTAL STRUCTURE OF HPNMT IN COMPLEX WITH ANTI-9-AMINO-5- (TRIFLUROMETHYL) BENZONORBORNENE AND ADOHCY | METHYLTRANSFERASE, CATECHOLAMINE BIOSYNTHESIS, POLYMORPHISM, S-ADENOSYL-L-METHIONINE, TRANSFERASE
3u7x:A (ASN118) to (ASP148) CRYSTAL STRUCTURE OF THE HUMAN EIF4E-4EBP1 PEPTIDE COMPLEX WITHOUT CAP | EIF4E, 4EBP1, MRNA EXPORT, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSLATION
3u7x:B (ASN118) to (ASP148) CRYSTAL STRUCTURE OF THE HUMAN EIF4E-4EBP1 PEPTIDE COMPLEX WITHOUT CAP | EIF4E, 4EBP1, MRNA EXPORT, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSLATION
4jyi:A (PRO347) to (GLU408) CRYSTAL STRUCTURE OF RARBETA LBD IN COMPLEX WITH SELECTIVE PARTIAL AGONIST BMS641 [3-CHLORO-4-[(E)-2-(5,5-DIMETHYL-8-PHENYL-5,6- DIHYDRONAPHTHALEN-2-YL)ETHENYL]BENZOIC ACID] | LIGAND BINDING DOMAIN, NUCLEAR HORMONE RECEPTOR, TRANSCRIPTION- AGONIST COMPLEX
1fdi:A (THR477) to (THR516) OXIDIZED FORM OF FORMATE DEHYDROGENASE H FROM E. COLI COMPLEXED WITH THE INHIBITOR NITRITE | OXIDOREDUCTASE, SELENIUM, SELENOCYSTEINE, SECYS, MOLYBDENUM, MOLYBDOPTERIN, MPT, MOLYBDOPTERIN GUANINE DINUCLEOTIDE, MGD, IRON SULFUR CLUSTER, FE4S4, FORMATE, DEHYDROGENASE, ANAEROBIC
4jza:A (ASP629) to (GLY662) CRYSTAL STRUCTURE OF A LEGIONELLA PHOSPHOINOSITIDE PHOSPHATASE: INSIGHTS INTO LIPID METABOLISM IN PATHOGEN HOST INTERACTION | ALPHA BETA FOLD, PHOSPHATASE, HYDROLASE
3ubv:A (ASP3) to (LEU42) OXYGEN-BOUND HELL'S GATE GLOBIN I BY CLASSICAL HANGING DROP | GLOBIN, OXYGEN-BOUND, AUTOXIDATION, OXYGEN, OXYGEN TRANSPORT
3ubv:D (ASP3) to (LEU42) OXYGEN-BOUND HELL'S GATE GLOBIN I BY CLASSICAL HANGING DROP | GLOBIN, OXYGEN-BOUND, AUTOXIDATION, OXYGEN, OXYGEN TRANSPORT
2esm:A (SER6) to (TYR59) CRYSTAL STRUCTURE OF ROCK 1 BOUND TO FASUDIL | KINASE, DIMER, DIMERIZATION, MYOSIN, TRANSFERASE
2esm:B (SER6) to (TYR59) CRYSTAL STRUCTURE OF ROCK 1 BOUND TO FASUDIL | KINASE, DIMER, DIMERIZATION, MYOSIN, TRANSFERASE
2etk:A (SER6) to (LYS60) CRYSTAL STRUCTURE OF ROCK 1 BOUND TO HYDROXYFASUDIL | DIMER, DIMERIZATION, KINASE, FASUDIL, HYDROXYFASUDIL, TRANSFERASE
2etk:B (SER6) to (LYS60) CRYSTAL STRUCTURE OF ROCK 1 BOUND TO HYDROXYFASUDIL | DIMER, DIMERIZATION, KINASE, FASUDIL, HYDROXYFASUDIL, TRANSFERASE
2v4z:A (SER62) to (SER113) THE CRYSTAL STRUCTURE OF THE HUMAN G-PROTEIN SUBUNIT ALPHA ( GNAI3) IN COMPLEX WITH AN ENGINEERED REGULATOR OF G- PROTEIN SIGNALING TYPE 2 DOMAIN (RGS2) | GTP HYDROLYSIS, ADP-RIBOSYLATION, NUCLEOTIDE-BINDING, LIPOPROTEIN, GTP-BINDING, PHOSPHOPROTEIN, SIGNAL TRANSDUCTION INHIBITOR, GUANINE NUCLEOTIDE BINDING PROTEIN, TRANSMEMBRANE SIGNALING, G-PROTEIN COUPLED RECEPTOR, PALMITATE, MYRISTATE, TRANSDUCER, CELL CYCLE
2etr:B (SER6) to (TYR59) CRYSTAL STRUCTURE OF ROCK I BOUND TO Y-27632 | DIMERIZATION, DIMER, PHOSPHORYLATION, KINASE, YOSHITOMI, TRANSFERASE
2v55:A (SER6) to (LYS60) MECHANISM OF MULTI-SITE PHOSPHORYLATION FROM A ROCK-I:RHOE COMPLEX STRUCTURE | SERINE/THREONINE-PROTEIN KINASE, RHOE, ZINC, KINASE, ROCK-I, MEMBRANE, APOPTOSIS, CYTOPLASM, G-PROTEINS, METHYLATION, ZINC-FINGER, NUCLEOTIDE-BINDING, PHORBOL-ESTER BINDING, ATP-BINDING, PRENYLATION, TRANSFERASE, LIPOPROTEIN, MULTI-SITE PHOSPHORYLATION, COILED COIL, GTP-BINDING, POLYMORPHISM, STRESS FIBRES, METAL-BINDING, PHOSPHOPROTEIN, GOLGI APPARATUS
2v55:C (PHE7) to (LYS60) MECHANISM OF MULTI-SITE PHOSPHORYLATION FROM A ROCK-I:RHOE COMPLEX STRUCTURE | SERINE/THREONINE-PROTEIN KINASE, RHOE, ZINC, KINASE, ROCK-I, MEMBRANE, APOPTOSIS, CYTOPLASM, G-PROTEINS, METHYLATION, ZINC-FINGER, NUCLEOTIDE-BINDING, PHORBOL-ESTER BINDING, ATP-BINDING, PRENYLATION, TRANSFERASE, LIPOPROTEIN, MULTI-SITE PHOSPHORYLATION, COILED COIL, GTP-BINDING, POLYMORPHISM, STRESS FIBRES, METAL-BINDING, PHOSPHOPROTEIN, GOLGI APPARATUS
3hkw:A (SER478) to (LYS523) HCV NS5B GENOTYPE 1A IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 6 | HCV POLYMERASE, SUBTYPE 1A, 1,5-BENZODIAZEPINE, TRANSFERASE
3hkw:B (SER478) to (LYS523) HCV NS5B GENOTYPE 1A IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 6 | HCV POLYMERASE, SUBTYPE 1A, 1,5-BENZODIAZEPINE, TRANSFERASE
3hky:A (SER478) to (ARG523) HCV NS5B POLYMERASE GENOTYPE 1B IN COMPLEX WITH 1,5 BENZODIAZEPINE 6 | HEPATITIS C VIRUS, 1,5-BENZODIAZEPINE, GENOTYPE, NS5B, POLYMERASE, BIACORE, REPLICON, TRANSFERASE
3hky:B (PRO479) to (PHE526) HCV NS5B POLYMERASE GENOTYPE 1B IN COMPLEX WITH 1,5 BENZODIAZEPINE 6 | HEPATITIS C VIRUS, 1,5-BENZODIAZEPINE, GENOTYPE, NS5B, POLYMERASE, BIACORE, REPLICON, TRANSFERASE
4yt2:A (ILE264) to (ASN301) HMD II FROM METHANOCALDOCOCCUS JANNASCHII | METAL BINDING PROTEIN, ROSSMANN-FOLD, OXIDOREDUCTASE
4yt2:B (GLY263) to (ASN301) HMD II FROM METHANOCALDOCOCCUS JANNASCHII | METAL BINDING PROTEIN, ROSSMANN-FOLD, OXIDOREDUCTASE
4yt5:A (ILE264) to (LEU302) HMDII FROM METHANOCALDOCOCCUS JANNASCHII WITH BOUND METHYLENE- TETRAHYDROMETHANOPTERIN | ROSSMANN-LIKE FOLD, [FE]-HYDROGENASE PARALOG, OXIDOREDUCTASE, METAL BINDING PROTEIN
4yt5:B (ILE264) to (ASN301) HMDII FROM METHANOCALDOCOCCUS JANNASCHII WITH BOUND METHYLENE- TETRAHYDROMETHANOPTERIN | ROSSMANN-LIKE FOLD, [FE]-HYDROGENASE PARALOG, OXIDOREDUCTASE, METAL BINDING PROTEIN
4yt8:A (ILE264) to (ASN301) SEMET-LABELLED HMDII FROM METHANOCALDOCOCCUS JANNASCHII | ROSSMANN-LIKE FOLD, [FE]-HYDROGENASE PARALOG, METAL BINDING PROTEIN
4yt8:B (GLY263) to (ASN301) SEMET-LABELLED HMDII FROM METHANOCALDOCOCCUS JANNASCHII | ROSSMANN-LIKE FOLD, [FE]-HYDROGENASE PARALOG, METAL BINDING PROTEIN
4k5y:A (LEU1039) to (LEU1091) CRYSTAL STRUCTURE OF HUMAN CORTICOTROPIN-RELEASING FACTOR RECEPTOR 1 (CRF1R) IN COMPLEX WITH THE ANTAGONIST CP-376395 | 7TM, GPCR, FAMILY B, SIGNALLING PROTEIN, G-PROTEIN, MEMBRANE, MEMBRANE PROTEIN, RECEPTOR
4k7k:A (SER127) to (LEU228) CRYSTAL STRUCTURES OF CUSC REVIEW CONFORMATIONAL CHANGES ACCOMPANYING FOLDING AND TRANSMEMBRANE CHANNEL FORMATION | BETA BARREL, MEMBRANE PROTEIN
4yve:A (SER6) to (LYS60) ROCK 1 BOUND TO METHOXYPHENYL THIAZOLE INHIBITOR | KINASE, DIMER, DIMERIZATION, MYOSIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4yvc:A (SER6) to (LYS60) ROCK 1 BOUND TO THIAZOLE INHIBITOR | KINASE, DIMER, DIMERIZATION, MYOSIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4yvc:B (SER6) to (LYS60) ROCK 1 BOUND TO THIAZOLE INHIBITOR | KINASE, DIMER, DIMERIZATION, MYOSIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2va8:A (GLU590) to (GLY644) DNA REPAIR HELICASE HEL308 | HEL308, SSO2462, HELICASE, HYDROLASE, DNA REPAIR, ATP-BINDING, NUCLEOTIDE-BINDING
2va8:B (GLU590) to (ARG642) DNA REPAIR HELICASE HEL308 | HEL308, SSO2462, HELICASE, HYDROLASE, DNA REPAIR, ATP-BINDING, NUCLEOTIDE-BINDING
2f2u:B (GLN27) to (TYR75) CRYSTAL STRUCTURE OF THE RHO-KINASE KINASE DOMAIN | ENZYME-INHIBITOR COMPLEX, TRANSFERASE
1rk2:C (ALA114) to (ALA135) E. COLI RIBOKINASE COMPLEXED WITH RIBOSE AND ADP, SOLVED IN SPACE GROUP P212121 | CARBOHYDRATE KINASE, RIBOSE, TRANSFERASE, INDUCED FIT, DOMAIN RE-ARRANGEMENTS
1fvh:A (TYR335) to (ASP394) CRYSTAL STRUCTURE ANALYSIS OF NEURONAL SEC1 FROM THE SQUID L. PEALEI | PARALLEL BETA-SHEETS, LEFT-HAND TURN CONNECTION, HELICAL BUNDLE, ENDOCYTOSIS/EXOCYTOSIS COMPLEX
4kb7:A (SER478) to (LYS523) HCV NS5B GT1B N316Y WITH CMPD 32 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, RNA-DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX
4kb7:B (SER478) to (LYS523) HCV NS5B GT1B N316Y WITH CMPD 32 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, RNA-DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX
4kbi:B (SER478) to (TYR524) HCV NS5B GT1B N316Y WITH CMPD 4 | HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, POLYMERASE, RNA DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX
1rsr:A (GLU260) to (ASN300) AZIDE COMPLEX OF THE DIFERROUS F208A MUTANT R2 SUBUNIT OF RIBONUCLEOTIDE REDUCTASE | DIIRON, AZIDE, OXYGEN ACTIVATION, OXIDOREDUCTASE
1rte:B (SER14) to (PHE46) X-RAY STRUCTURE OF CYANIDE DERIVATIVE OF TRUNCATED HEMOGLOBIN N (TRHBN) FROM MYCOBACTERIUM TUBERCULOSIS | TRUNCATED HEMOGLOBIN, OXYGEN STORAGE/TRANSPORT COMPLEX
3hor:B (LEU172) to (SER215) STRUCTURE OF THE ACTIN-BINDING DOMAIN OF HUMAN FILAMIN A (REDUCED) | CALPONIN HOMOLOGY DOMAIN, ACTIN BINDING DOMAIN, ACETYLATION, ACTIN-BINDING, ALTERNATIVE SPLICING, CYTOPLASM, CYTOSKELETON, DISEASE MUTATION, PHOSPHOPROTEIN, POLYMORPHISM, STRUCTURAL PROTEIN
3uph:B (SER478) to (PHE526) SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3upi:B (SER478) to (ARG523) SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4z3x:A (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH 1-MONOENOYL-COA | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3x:B (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH 1-MONOENOYL-COA | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3x:C (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH 1-MONOENOYL-COA | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3x:D (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH 1-MONOENOYL-COA | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3y:A (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH BENZOYL-COA | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3y:B (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH BENZOYL-COA | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3y:C (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH BENZOYL-COA | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3y:D (GLU606) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH BENZOYL-COA | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3z:A (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH ZINC | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3z:B (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH ZINC | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3z:C (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH ZINC | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3z:D (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH ZINC | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z40:A (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE AS ISOLATED | AROMATICS, OXIDOREDUCTASE, BENZOYL-COA, ANAEROBIC
4z40:B (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE AS ISOLATED | AROMATICS, OXIDOREDUCTASE, BENZOYL-COA, ANAEROBIC
4z40:C (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE AS ISOLATED | AROMATICS, OXIDOREDUCTASE, BENZOYL-COA, ANAEROBIC
4z40:D (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE AS ISOLATED | AROMATICS, OXIDOREDUCTASE, BENZOYL-COA, ANAEROBIC
4kl7:D (GLN313) to (GLY360) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF RPFB FROM MYCOBACTERIUM TUBERCULOSIS | CELL WALL HYDROLASE, HYDROLASE
4zad:A (THR375) to (HIS410) STRUCTURE OF C. DUBLIENSIS FDC1 WITH THE PRENYLATED-FLAVIN COFACTOR IN THE IMINIUM FORM. | (DE)CARBOXYLASE, PRENYLATED FLAVIN BINDING, UBID-TYPE ENZYME, LYASE
4zad:B (THR375) to (HIS410) STRUCTURE OF C. DUBLIENSIS FDC1 WITH THE PRENYLATED-FLAVIN COFACTOR IN THE IMINIUM FORM. | (DE)CARBOXYLASE, PRENYLATED FLAVIN BINDING, UBID-TYPE ENZYME, LYASE
1s5j:A (GLU589) to (GLU647) INSIGHT IN DNA REPLICATION: THE CRYSTAL STRUCTURE OF DNA POLYMERASE B1 FROM THE ARCHAEON SULFOLOBUS SOLFATARICUS | DNA POLYMERASE, REPLICATION, DISULFIDE BONDS, TRANSFERASE
2fss:C (GLY117) to (ALA159) CANDIDA BOIDINII FORMATE DEHYDROGENASE (FDH) K47E MUTANT | ROSSMANN FOLD, PROTEIN HOMO DIMER, NAD BINDING SITE, FORMATE BINDING SITE, OXIDOREDUCTASE
4zda:F (ASP680) to (PRO732) CRYSTAL STRUCTURE OF ISOCITRATE DEHYDROGENASE IN COMPLEX WITH ISOCITRATE AND MN FROM M. SMEGMATIS | ICD, M. SMEGMATIS, COMPLEX, ISOCITRATE, OXIDOREDUCTASE
4knh:A (GLY108) to (GLY166) STRUCTURE OF THE CHAETOMIUM THERMOPHILUM ADAPTOR NUCLEOPORIN NUP192 N- TERMINAL DOMAIN | HEAT REPEAT PROTEIN, ARM REPEAT PROTEIN, NUCLEAR PORE COMPLEX, TRANSPORT PROTEIN
4knh:B (GLY108) to (GLY166) STRUCTURE OF THE CHAETOMIUM THERMOPHILUM ADAPTOR NUCLEOPORIN NUP192 N- TERMINAL DOMAIN | HEAT REPEAT PROTEIN, ARM REPEAT PROTEIN, NUCLEAR PORE COMPLEX, TRANSPORT PROTEIN
1scf:C (PRO40) to (LYS91) HUMAN RECOMBINANT STEM CELL FACTOR | HUMAN STEM CELL FACTOR, STEEL FACTOR, KIT LIGAND, MAST CELL GROWTH FACTOR, HORMONE/GROWTH FACTOR COMPLEX
3hxr:A (ILE564) to (LEU639) NUCLEOPORIN NUP120 FROM S.CEREVISIAE (AA 1-757) | STRUCTURAL PROTEIN, COILED COIL, MEMBRANE, MRNA TRANSPORT, NUCLEAR PORE COMPLEX, NUCLEUS, PHOSPHOPROTEIN, PROTEIN TRANSPORT, TRANSLOCATION, TRANSPORT
3hxr:A (ASP643) to (SER683) NUCLEOPORIN NUP120 FROM S.CEREVISIAE (AA 1-757) | STRUCTURAL PROTEIN, COILED COIL, MEMBRANE, MRNA TRANSPORT, NUCLEAR PORE COMPLEX, NUCLEUS, PHOSPHOPROTEIN, PROTEIN TRANSPORT, TRANSLOCATION, TRANSPORT
3hxu:A (ASN304) to (GLN352) CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS IN COMPLEX WITH ALASA | AMINOACYL-TRNA SYNTHETASE, LIGASE, PROTEIN BIOSYNTHESIS, NUCLEOTIDE- BINDING, AMINO ACID-BINDING, ATP-BINDING, METAL-BINDING, ZINC-FINGER
2fvc:A (SER478) to (PHE526) CRYSTAL STRUCTURE OF NS5B BK STRAIN (DELTA 24) IN COMPLEX WITH A 3-(1, 1-DIOXO-2H-(1,2,4)-BENZOTHIADIAZIN-3-YL)-4-HYDROXY-2(1H)-QUINOLINONE | HCV POLYMERASE, THIADIAZIN INHIBITOR, TRANSFERASE
2fvc:B (SER478) to (TYR524) CRYSTAL STRUCTURE OF NS5B BK STRAIN (DELTA 24) IN COMPLEX WITH A 3-(1, 1-DIOXO-2H-(1,2,4)-BENZOTHIADIAZIN-3-YL)-4-HYDROXY-2(1H)-QUINOLINONE | HCV POLYMERASE, THIADIAZIN INHIBITOR, TRANSFERASE
3hxy:A (ASN304) to (GLN352) CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS IN COMPLEX WITH AMPPCP, ALA-AMP AND PCP | AMINOACYL-TRNA SYNTHETASE, LIGASE, PROTEIN BIOSYNTHESIS, NUCLEOTIDE- BINDING, AMINO ACID-BINDING, ATP-BINDING, METAL-BINDING, ZINC-FINGER
3hxz:A (ASN304) to (GLN352) CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS G237A IN COMPLEX WITH ALASA | AMINOACYL-TRNA SYNTHETASE, LIGASE, PROTEIN BIOSYNTHESIS, NUCLEOTIDE- BINDING, AMINO ACID-BINDING, ATP-BINDING, METAL-BINDING, ZINC-FINGER
1sdk:A (PRO4) to (PHE43) CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A | HEME, OXYGEN TRANSPORT, RESPIRATORY PROTEIN, ERYTHROCYTE, DISEASE MUTATION, POLYMORPHISM
1sdl:C (PRO4) to (PHE43) CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A | HEME, OXYGEN TRANSPORT, RESPIRATORY PROTEIN, ERYTHROCYTE, DISEASE MUTATION, POLYMORPHISM, ACETYLATION
2fxs:A (TYR24) to (GLU59) YEAST HSP82 IN COMPLEX WITH THE NOVEL HSP90 INHIBITOR RADAMIDE | HSP82, HSP90, GRP94, HTPG, CHAPERONE, LIGAND, RADICICOL, GELDANAMYCIN, RADESTER
4kqa:B (THR115) to (ASN161) CRYSTAL STRUCTURE OF THE GOLGI CASEIN KINASE | SECRETED KINASE, TRANSFERASE
3v6q:A (PRO197) to (LEU283) CRYSTAL STRUCTURE OF THE COMPLEX OF BOVINE LACTOPEROXIDASE WITH CARBON MONOXIDE AT 2.0 A RESOLUTION | IODIDE, CARBON MONOXIDE, LACTOPEROXIDASE, DISTAL HEME BINDING SITE, OXIDOREDUCTASE
1shz:A (ASP77) to (ALA124) CRYSTAL STRUCTURE OF THE P115RHOGEF RGRGS DOMAIN IN A COMPLEX WITH GALPHA(13):GALPHA(I1) CHIMERA | SIGNAL TRANSDUCTION, PROTEIN COMPLEX, SIGNALING PROTEIN
1skf:A (THR113) to (THR176) CRYSTAL STRUCTURE OF THE STREPTOMYCES K15 DD-TRANSPEPTIDASE | PENICILLIN-BINDING, DD-TRANSPEPTIDASE, SERINE PEPTIDASE, BETA- LACTAMASE, HYDROLASE CARBOXYPEPTIDASE
4ksk:A (TYR165) to (PHE219) GUMBY/FAM105B IN COMPLEX WITH UBIQUITIN | OTU DOMAIN, DEUBIQUITINASE, UBIQUITIN, HYDROLASE, HYDROLASE-PROTEIN BINDING COMPLEX
1gqt:D (ALA114) to (ALA135) ACTIVATION OF RIBOKINASE BY MONOVALENT CATIONS | CARBOHYDRATE KINASE, RIBOSE, TRANSFERASE, INDUCED FIT, BINDING OF MONOVALENT CATIONS, ACTIVATION BY MONOVALENT CATIONS
1smk:G (THR239) to (GLY288) MATURE AND TRANSLOCATABLE FORMS OF GLYOXYSOMAL MALATE DEHYDROGENASE HAVE DIFFERENT ACTIVITIES AND STABILITIES BUT SIMILAR CRYSTAL STRUCTURES | TRICARBOXYLIC CYCLE, GLYOXYSOME, NAD, GLYOXYLATE BYPASS, OXIDOREDUCTASE
2g54:A (ASP655) to (LEU689) CRYSTAL STRUCTURE OF ZN-BOUND HUMAN INSULIN-DEGRADING ENZYME IN COMPLEX WITH INSULIN B CHAIN | PROTEIN-PEPTIDE COMPLEX, HYDROLASE
1smy:D (ALA458) to (ASP504) STRUCTURAL BASIS FOR TRANSCRIPTION REGULATION BY ALARMONE PPGPP | RNA POLYMERASE HOLOENZYME, GUANOSINE-TETRAPHOSPHATE, PPGPP, TRANSCRIPTION REGULATION, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
2vt4:A (GLU41) to (LEU92) TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND CYANOPINDOLOL | GPCR, MEMBRANE, RECEPTOR, PALMITATE, TRANSDUCER, ANTAGONIST BOUND FORM, INTEGRAL MEMBRANE PROTEIN, G-PROTEIN COUPLED RECEPTOR, G PROTEIN COUPLED RECEPTOR, THERMOSTABILISING POINT MUTATIONS, PHOSPHOPROTEIN, SEVEN-HELIX RECEPTOR, LIPOPROTEIN, 7TM RECEPTOR, GLYCOPROTEIN, TRANSMEMBRANE
2vt4:D (GLU41) to (LEU92) TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND CYANOPINDOLOL | GPCR, MEMBRANE, RECEPTOR, PALMITATE, TRANSDUCER, ANTAGONIST BOUND FORM, INTEGRAL MEMBRANE PROTEIN, G-PROTEIN COUPLED RECEPTOR, G PROTEIN COUPLED RECEPTOR, THERMOSTABILISING POINT MUTATIONS, PHOSPHOPROTEIN, SEVEN-HELIX RECEPTOR, LIPOPROTEIN, 7TM RECEPTOR, GLYCOPROTEIN, TRANSMEMBRANE
4kx9:A (ASP841) to (ASN874) CRYSTAL STRUCTURE OF HUMAN AMINOPEPTIDASE A COMPLEXED WITH ARGININE | ZINC-AMINOPEPTIDASE, HYDROLASE
4kxc:A (ASP841) to (ASN874) CRYSTAL STRUCTURE OF HUMAN AMINOPEPTIDASE A COMPLEXED WITH GLUTAMATE | ZINC-AMINOPEPTIDASE, HYDROLASE
4kxd:A (ASP841) to (ASN874) CRYSTAL STRUCTURE OF HUMAN AMINOPEPTIDASE A COMPLEXED WITH GLUTAMATE AND CALCIUM | ZINC-AMINOPEPTIDASE, HYDROLASE
2vvs:A (LYS489) to (GLN543) BTGH84 STRUCTURE IN COMPLEX WITH PUGNAC | HYDROLASE, INHIBITOR, GLYCOSIDE HYDROLASE, O-GLCNAC
1gvi:A (GLY249) to (TRP270) THERMUS MALTOGENIC AMYLASE IN COMPLEX WITH BETA-CD | AMYLASE, TRANSGLYCOSYLATION, BETA-CYCLODEXTRIN, HYDROLASE
1gws:A (HIS267) to (ILE338) HEXADECAHEME HIGH MOLECULAR WEIGHT CYTOCHROME HMC FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH | ELECTRON TRANSPORT, MULTIHEME CYTOCHROME, SULFATE REDUCING BACTERIA, PERIPLASMIC, HEME
1gx6:A (SER478) to (ASN527) HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH UTP AND MANGANESE | POLYMERASE, RNA-DEPENDENT RNA POLYMERASE, VIRUS REPLICATION, INITIATION, POLYPROTEIN, GLYCOPROTEIN, TRANSFERASE, RNA-DIRECTED RNA POLYMERASE
2gc8:B (SER478) to (LYS523) STRUCTURE OF A PROLINE SULFONAMIDE INHIBITOR BOUND TO HCV NS5B POLYMERASE | TRANSFERASE
4kzi:A (SER550) to (LEU596) CRYSTAL STRUCTURE OF TR3 LBD IN COMPLEX WITH DPDO | ORPHAN NUCLEAR RECEPTOR, TRANSCRIPTION
1t0q:A (TYR55) to (ALA101) STRUCTURE OF THE TOLUENE/O-XYLENE MONOOXYGENASE HYDROXYLASE | DIIRON, CARBOXYLATE BRIDGE, 4-HELIX BUNDLE, CHANNEL, OXIDOREDUCTASE
2giq:A (SER478) to (LYS523) HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B WITH NNI-2 INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE
3vjd:A (THR2) to (GLU71) CRYSTAL STRUCTURE OF THE Y248A MUTANT OF C(30) CAROTENOID DEHYDROSQUALENE SYNTHASE FROM STAPHYLOCOCCUS AUREUS | CRTM, CAROTENOID BIOSYNTHESIS, STAPHYLOXANTHIN BIOSYNTHESIS, TRANSFERASE, HEAD-TO-HEAD CONDENSATION
1t3a:B (GLY256) to (TYR306) CRYSTAL STRUCTURE OF CLOSTRIDIUM BOTULINUM NEUROTOXIN TYPE E CATALYTIC DOMAIN | CLOSTRIDIUM BOTULINUM, CATALYTIC DOMAIN, LIGHT CHAIN, HYDROLASE, TOXIN
2gkn:B (SER14) to (PHE46) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TRHBN, GLNE11VAL MUTANT | TRUNCATED HEMOGLOBIN; MUTANT, OXYGEN STORAGE/TRANSPORT COMPLEX
2gnw:B (SER14) to (SER55) CRYSTAL STRUCTURE OF NON-SYMBIOTIC PLANT HEMOGLOBIN FROM RICE, B10 MUTANT F40W | 2 ON 2 HELICAL FOLD, GLOBIN, HEME, IRON, HEMOGLOBIN, HEXACOORDINATE, NONSYMBIOTIC, RICE, OXYGEN STORAGE/TRANSPORT COMPLEX
4l6q:A (LYS29) to (TYR75) ROCK2 IN COMPLEX WITH BENZOXABOROLE | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3if6:A (GLU134) to (ILE198) CRYSTAL STRUCTURE OF OXA-46 BETA-LACTAMASE FROM P. AERUGINOSA | SERINE BETA-LACTAMASE, HYDROLASE
3if6:C (GLU134) to (ILE198) CRYSTAL STRUCTURE OF OXA-46 BETA-LACTAMASE FROM P. AERUGINOSA | SERINE BETA-LACTAMASE, HYDROLASE
1h5x:A (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-13 COMPLEXED WITH IMIPENEM | HYDROLASE, ACYL-ENZYME
1h5x:B (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-13 COMPLEXED WITH IMIPENEM | HYDROLASE, ACYL-ENZYME
2gp4:A (ILE344) to (THR382) STRUCTURE OF [FES]CLUSTER-FREE APO FORM OF 6-PHOSPHOGLUCONATE DEHYDRATASE FROM SHEWANELLA ONEIDENSIS | N-TERMINAL DOMAIN LARGELY ALPHA-HELICAL, C-TERMINAL DOMAIN MAINLY BETA-SHEET (TREFOIL-LIKE), STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, SOUTHEAST COLLABORATORY FOR STRUCTURAL GENOMICS, SECSG, LYASE
2gp4:B (ILE344) to (THR382) STRUCTURE OF [FES]CLUSTER-FREE APO FORM OF 6-PHOSPHOGLUCONATE DEHYDRATASE FROM SHEWANELLA ONEIDENSIS | N-TERMINAL DOMAIN LARGELY ALPHA-HELICAL, C-TERMINAL DOMAIN MAINLY BETA-SHEET (TREFOIL-LIKE), STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, SOUTHEAST COLLABORATORY FOR STRUCTURAL GENOMICS, SECSG, LYASE
1t7n:A (PRO488) to (HIS548) CRYSTAL STRUCTURE OF THE M564G MUTANT OF MURINE CRAT | TRANSFERASE
2grn:A (THR108) to (PHE155) CRYSTAL STRUCTURE OF HUMAN RANGAP1-UBC9 | UBIQUITIN, CONJUGATION, SMALL UBIQUITIN LIKE MODIFER, SMT3, LIGASE
2gro:A (THR108) to (PHE155) CRYSTAL STRUCTURE OF HUMAN RANGAP1-UBC9-N85Q | UBIQUITIN, CONJUGATION, SMALL UBIQUITIN LIKE MODIFER, SMT3, LIGASE
2grq:A (THR108) to (PHE155) CRYSTAL STRUCTURE OF HUMAN RANGAP1-UBC9-D127A | UBIQUITIN, CONJUGATION, SMALL UBIQUITIN LIKE MODIFER, SMT3, LIGASE
2grr:A (THR108) to (PHE155) CRYSTAL STRUCTURE OF HUMAN RANGAP1-UBC9-D127S | UBIQUITIN, CONJUGATION, SMALL UBIQUITIN LIKE MODIFER, SMT3, LIGASE
3ihp:A (ARG415) to (PHE461) COVALENT UBIQUITIN-USP5 COMPLEX | HYDROLASE, PROTEASE, THIOL PROTEASE, UBL CONJUGATION PATHWAY, METAL-BINDING, ZINC-FINGER,STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, ACETYLATION, ALTERNATIVE SPLICING, PHOSPHOPROTEIN, ZINC, CYTOPLASM, ISOPEPTIDE BOND, NUCLEUS, UBL CONJUGATION
4l93:B (TYR38) to (GLY73) CRYSTAL STRUCTURE OF HUMAN HSP90 WITH S36 | ATP HYDROLYSIS, HSP90N-HSP90N INHIBITOR COMPLEX, CHAPERONE-CHAPERONE INHIBITOR COMPLEX
4l94:A (TYR38) to (GLY73) CRYSTAL STRUCTURE OF HUMAN HSP90 WITH S46 | ATP HYDROLYSIS, HSP90N-HSP90N INHIBITOR COMPLEX, CHAPERONE-CHAPERONE INHIBITOR COMPLEX
1h8z:A (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-13 | HYDROLASE, BETA-LACTAMASE, CLASS D, OXACILLINASE, OXA-13
1h8z:B (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-13 | HYDROLASE, BETA-LACTAMASE, CLASS D, OXACILLINASE, OXA-13
1tc0:A (ALA77) to (ASN129) LIGAND INDUCED CONFORMATIONAL SHIFTS IN THE N-TERMINAL DOMAIN OF GRP94, OPEN CONFORMATION COMPLEXED WITH THE PHYSIOLOGICAL PARTNER ATP | GRP94, HSP90, ATP, BERGERAT, CHAPERONE, ENDOPLASMIC RETICULUM
1tc6:A (ALA77) to (ASN129) LIGAND INDUCED CONFORMATIONAL SHIFT IN THE N-TERMINAL DOMAIN OF GRP94, OPEN CONFORMATION ADP-COMPLEX | GRP94, HSP90, ADP, BERGERAT, CHAPERONE, ENDOPLASMIC RETICULUM
2w67:B (LYS489) to (SER545) BTGH84 IN COMPLEX WITH FMA34 | GLYCOSIDE HYDROLASE, COMPLEX, HYDROLASE, INHIBITOR, GLYCOSIDASE
2w66:A (LYS489) to (GLN543) BTGH84 IN COMPLEX WITH HQ602 | GLYCOSIDE HYDROLASE, COMPLEX, HYDROLASE, INHIBITOR, GLYCOSIDASE
1hbr:C (THR3) to (PHE43) R-STATE FORM OF CHICKEN HEMOGLOBIN D | HEMOGLOBIN D (R-STATE) 1, HEMOGLOBIN, AVIAN, HIGH COOPERATIITY, OXYGEN TRANSPORT, OXYGEN STORAGE/TRANSPORT COMPLEX
1tjl:E (SER13) to (GLU109) CRYSTAL STRUCTURE OF TRANSCRIPTION FACTOR DKSA FROM E. COLI | DKSA, TRANSCRIPTION FACTOR, RNA POLYMERASE, STRINGENT RESPONSE, PPGPP, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSCRIPTION
1tjl:G (SER13) to (GLU109) CRYSTAL STRUCTURE OF TRANSCRIPTION FACTOR DKSA FROM E. COLI | DKSA, TRANSCRIPTION FACTOR, RNA POLYMERASE, STRINGENT RESPONSE, PPGPP, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSCRIPTION
2w97:A (ASN118) to (ASP148) CRYSTAL STRUCTURE OF EIF4E BOUND TO GLYCEROL AND EIF4G1 PEPTIDE | PROTEIN BIOSYNTHESIS, INITIATION FACTOR, TRANSLATION REGULATION, TRANSLATION
2w97:B (ASN118) to (ASP148) CRYSTAL STRUCTURE OF EIF4E BOUND TO GLYCEROL AND EIF4G1 PEPTIDE | PROTEIN BIOSYNTHESIS, INITIATION FACTOR, TRANSLATION REGULATION, TRANSLATION
2h3p:A (GLU489) to (HIS548) CRYSTAL STRUCTURE OF MURINE CARNITINE ACETYLTRANSFERASE IN COMPLEX WITH CARNITINE AND ACETYL-COA | CARNITINE ACYLTRANSFERASE
2h3p:B (GLU489) to (HIS548) CRYSTAL STRUCTURE OF MURINE CARNITINE ACETYLTRANSFERASE IN COMPLEX WITH CARNITINE AND ACETYL-COA | CARNITINE ACYLTRANSFERASE
2w9m:B (GLY106) to (ARG158) STRUCTURE OF FAMILY X DNA POLYMERASE FROM DEINOCOCCUS RADIODURANS | SAXS, DNA REPAIR, DNA POLYMERASE, DNA REPLICATION
2wa7:A (THR140) to (PRO184) STRUCTURE OF THE M202V MUTANT OF HUMAN FILAMIN B ACTIN BINDING DOMAIN AT 1.85 ANGSTROMS RESOLUTION | DISEASE MUTATION, SKELETAL DYSPLASIA, STRUCTURAL PROTEIN, ACTIN-CROSSLINKING, MYOGENESIS, CYTOSKELETON, ACTIN-BINDING, CALPONIN HOMOLOGY DOMAIN, PHOSPHOPROTEIN, DIFFERENTIATION, ATELOSTEOGENESIS, MUTANT, FILAMIN, DWARFISM, CH DOMAIN, DEVELOPMENTAL PROTEIN
4ljz:D (ALA182) to (SER230) CRYSTAL STRUCTURE ANALYSIS OF THE E.COLI HOLOENZYME | DNA DIRECTED RNA POLYMERASE, TRANSFERASE
4ljz:J (ALA182) to (SER230) CRYSTAL STRUCTURE ANALYSIS OF THE E.COLI HOLOENZYME | DNA DIRECTED RNA POLYMERASE, TRANSFERASE
2h9v:A (SER25) to (GLU76) STRUCTURAL BASIS FOR INDUCED-FIT BINDING OF RHO-KINASE TO THE INHIBITOR Y27632 | PROTEIN KINASE-INHIBITOR COMPLEX, TRANSFERASE
2wcx:A (PRO479) to (TYR524) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN COMPLEX WITH THIENOPYRROLE-BASED FINGER-LOOP INHIBITORS | ENVELOPE PROTEIN, HEPATITIS C VIRUS, RNA-DEPENDENT RNA-POLYMERASE, NUCLEOTIDE-BINDING, ALLOSTERIC INHIBITOR, NON NUCLEOSIDE INHIBITOR, NNI, HCV, NS5B, MEMBRANE, HELICASE, HYDROLASE, POLYMERASE, ATP-BINDING, RNA-BINDING, GENOTYPE 1B, VIRAL PROTEIN, TRANSMEMBRANE, RNA REPLICATION
2wep:A (TYR24) to (GLU59) YEAST HSP90 N-TERMINAL DOMAIN LI-IV MUTANT WITH ADP | ATPASE, CHAPERONE, ATP-BINDING, PHOSPHOPROTEIN, STRESS RESPONSE, NUCLEOTIDE-BINDING
3von:E (GLN100) to (ASN150) CRYSTALSTRUCTURE OF THE UBIQUITIN PROTEASE | UBIQUITIN PROTEASE, HYDROLASE-LIGASE COMPLEX
3vqs:A (SER478) to (PHE526) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vqs:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vqs:C (SER478) to (PHE526) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vqs:D (SER478) to (LYS523) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2wgi:A (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE ACYL-ENZYME OXA-10 W154A- BENZYLPENICILLIN AT PH 6 | HYDROLASE-ANTIBIOTIC COMPLEX, HYDROLASE ANTIBIOTIC COMPLEX, LYSINE CARBOXYLATION, HYDROLASE, ACYL-ENZYME, ANTIBIOTIC RESISTANCE, CLASS D BETA-LACTAMASE
2wgv:A (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 V117T MUTANT AT PH 6.5 INHIBITED BY A CHLORIDE ION | ANTIBIOTIC RESISTANCE, PLASMID ENCODED, HYDROLASE
2wgv:B (MET132) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 V117T MUTANT AT PH 6.5 INHIBITED BY A CHLORIDE ION | ANTIBIOTIC RESISTANCE, PLASMID ENCODED, HYDROLASE
2wi3:A (TYR38) to (GLY73) ORALLY ACTIVE 2-AMINO THIENOPYRIMIDINE INHIBITORS OF THE HSP90 CHAPERONE | CHAPERONE, HEAT SHOCK, STRESS RESPONSE, NUCLEOTIDE-BINDING
2wi5:A (TYR38) to (GLY73) ORALLY ACTIVE 2-AMINO THIENOPYRIMIDINE INHIBITORS OF THE HSP90 CHAPERONE | PU3, HSP90, ATPASE, CHAPERONE, HEAT SHOCK, STRESS RESPONSE, NUCLEOTIDE-BINDING, ATP-BINDING, PHOSPHOPROTEIN, PHOSPHORYLATION
4lnv:C (ASN996) to (ASN1037) CRYSTAL STRUCTURE OF TEP1S | IMMUNE SYSTEM, INNATE IMMUNITY, LRIM1 AND APL1C
2hp5:B (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 W154G MUTANT AT PH 7.0 | CLASS D BETA-LACTAMASE, LYSINE CARBOXYLATION, HYDROLASE
2hp5:C (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 W154G MUTANT AT PH 7.0 | CLASS D BETA-LACTAMASE, LYSINE CARBOXYLATION, HYDROLASE
2hp5:D (VAL130) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 W154G MUTANT AT PH 7.0 | CLASS D BETA-LACTAMASE, LYSINE CARBOXYLATION, HYDROLASE
2hp6:A (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 W154A MUTANT AT PH 7.5 | CLASS D BETA-LACTAMASE, LYSINE CARBOXYLATION, HYDROLASE
2hp6:B (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 W154A MUTANT AT PH 7.5 | CLASS D BETA-LACTAMASE, LYSINE CARBOXYLATION, HYDROLASE
2hp9:A (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 W154A MUTANT AT PH 6.0 | CLASS D BETA-LACTAMASE, LYSINE CARBOXYLATION, HYDROLASE
2hp9:B (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 W154A MUTANT AT PH 6.0 | CLASS D BETA-LACTAMASE, LYSINE CARBOXYLATION, HYDROLASE
2hpb:A (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 W154A MUTANT AT PH 9.0 | CLASS D BETA-LACTAMASE, LYSINE CARBOXYLATION, HYDROLASE
2hpb:B (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 W154A MUTANT AT PH 9.0 | CLASS D BETA-LACTAMASE, LYSINE CARBOXYLATION, HYDROLASE
2wkh:A (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE ACYL-ENZYME OXA-10 K70C-AMPICILLIN AT PH 7 | HYDROLASE, ANTIBIOTIC RESISTANCE, CLASS D BETA-LACTAMASE, PLASMID ENCODED
2wkh:B (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE ACYL-ENZYME OXA-10 K70C-AMPICILLIN AT PH 7 | HYDROLASE, ANTIBIOTIC RESISTANCE, CLASS D BETA-LACTAMASE, PLASMID ENCODED
2wki:A (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 K70C MUTANT AT PH 7.0 | CLASS D, PLASMID ENCODED, HYDROLASE, ANTIBIOTIC RESISTANCE, BETA-LACTAMASE
3vwa:A (SER163) to (GLY222) CRYSTAL STRUCTURE OF CEX1P | TRNA, NUCLEAR EXPORT, HEAT REPEAT, KINASE LIKE DOMAIN, HYDROLASE
3vwa:B (PHE165) to (GLY222) CRYSTAL STRUCTURE OF CEX1P | TRNA, NUCLEAR EXPORT, HEAT REPEAT, KINASE LIKE DOMAIN, HYDROLASE
4lw2:A (PRO6) to (GLU66) STRUCTURAL CHANGES DURING CYSTEINE DESULFURASE CSDA AND SULFUR- ACCEPTOR CSDE INTERACTIONS PROVIDE INSIGHT INTO THE TRANS- PERSULFURATION | CYSTEINE DESULFURASE, CSDA, SUFS, LYASE
4lw2:B (PRO6) to (ALA68) STRUCTURAL CHANGES DURING CYSTEINE DESULFURASE CSDA AND SULFUR- ACCEPTOR CSDE INTERACTIONS PROVIDE INSIGHT INTO THE TRANS- PERSULFURATION | CYSTEINE DESULFURASE, CSDA, SUFS, LYASE
4lx8:A (MET63) to (PRO85) CRYSTAL STRUCTURE (2.2A) OF MG2+ BOUND CHEY3 OF VIBRIO CHOLERAE | SIGNALING PROTEIN, ROSSMANN FOLD, RESPONSE REGULATOR, MAGNESIUM BINDING, SIGNAL TRANSDUCTION
1i7k:B (ASP127) to (THR175) CRYSTAL STRUCTURE OF HUMAN MITOTIC-SPECIFIC UBIQUITIN- CONJUGATING ENZYME, UBCH10 | UBIQUITIN CONJUGATING ENZYME, LIGASE
1u9b:A (THR108) to (PHE155) MURINE/HUMAN UBIQUITIN-CONJUGATING ENZYME UBC9 | UBIQUITIN-CONJUGATING ENZYME, UBIQUITIN-DIRECTED PROTEOLYSIS, CELL CYCLE CONTROL, LIGASE
3w3z:A (GLY691) to (ILE725) CRYSTAL STRUCTURE OF KAP121P BOUND TO RANGTP | HEAT REPEAT, NUCLEAR IMPORT, PROTEIN TRANSPORT-NUCLEAR PROTEIN COMPLEX
2wsx:C (LEU135) to (GLY186) CRYSTAL STRUCTURE OF CARNITINE TRANSPORTER FROM ESCHERICHIA COLI | MEMBRANE PROTEIN, TRANSPORT PROTEIN
1ibe:A (SER3) to (PHE43) DEOXY-HAEMOGLOBIN TRAPPED IN THE HIGH-AFFINITY (R) STATE | HEME, OXYGEN TRANSPORT, RESPIRATORY PROTEIN, ERYTHROCYTE
1idr:B (SER14) to (PHE46) CRYSTAL STRUCTURE OF THE TRUNCATED-HEMOGLOBIN-N FROM MYCOBACTERIUM TUBERCULOSIS | TRUNCATED HEMOGLOBIN FOLD, OXYGEN STORAGE/TRANSPORT COMPLEX
1uf2:A (PRO399) to (GLN436) THE ATOMIC STRUCTURE OF RICE DWARF VIRUS (RDV) | VIRUS COMPONENTS, ICOSAHEDRAL VIRUS
1ufa:A (PRO61) to (SER121) CRYSTAL STRUCTURE OF TT1467 FROM THERMUS THERMOPHILUS HB8 | STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, UNKNOWN FUNCTION
4m25:C (SER35) to (ASP67) CRYSTAL STRUCTURE OF NON-HEME IRON OXYGENASE ORFP IN COMPLEX WITH FE AND ALPHA-KETOGLUTARIC ACID | HYDROXYLASE, FE BINDING, OXIDOREDUCTASE
4m27:C (SER35) to (ASP67) CRYSTAL STRUCTURE OF NON-HEME IRON OXYGENASE ORFP IN COMPLEX WITH FE AND L-ARG | HYDROXYLASE, FE BINDING, OXIDOREDUCTASE
4m2e:C (SER35) to (ASP67) CRYSTAL STRUCTURE OF NON-HEME IRON OXYGENASE ORFP IN COMPLEX WITH FE AND L-HOMOARGININE | HYDROXYLASE, FE BINDING, OXIDOREDUCTASE
5a6j:B (ASP423) to (HIS457) GH20C, BETA-HEXOSAMINIDASE FROM STREPTOCOCCUS PNEUMONIAE | HYDROLASE, BETA-HEXOSAMINIDASE, STREPTOCOCCUS PNEUMONIAE, BACTERIAL PROTEINS, CARBOHYDRATE CONFORMATION, CATALYTIC DOMAIN, HOST-PATHOGEN INTERACTIONS, HYDROGEN BONDING, HYDROLYSIS, MODELS, POLYSACCHARIDES, VIRULENCE FACTORS
4m2f:C (SER35) to (ASP67) CRYSTAL STRUCTURE OF NON-HEME IRON OXYGENASE ORFP IN COMPLEX WITH FE AND L-CANAVANINE | HYDROXYLASE, FE BINDING, OXIDOREDUCTASE
5a7d:M (PRO549) to (HIS596) TETRAMERIC ASSEMBLY OF LGN WITH INSCUTEABLE | CELL CYCLE, LGN, INSCUTEABLE, ASYMMETRIC CELL DIVISION
2i6l:B (LYS211) to (VAL262) CRYSTAL STRUCTURE OF HUMAN MITOGEN ACTIVATED PROTEIN KINASE 6 (MAPK6) | MAPK6, ERK3, MITOGEN ACTIVATED PROTEIN KINASE 6, EXTRACELLULAR SIGNAL REGULATED KINASE 3, SERINE PHOSPHORYLATION, THREONINE PHOSPHORYLATION, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
2iae:E (GLN151) to (GLY191) CRYSTAL STRUCTURE OF A PROTEIN PHOSPHATASE 2A (PP2A) HOLOENZYME. | PROTEIN PHOSPHORYLATION, PHOSPHATASE, PP2A, B56, TUMOR SUPPRESSOR, METHYLATION, HYDROLASE, TOXIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2ib1:A (GLY194) to (SER220) SOLUTION STRUCTURE OF P45 DEATH DOMAIN | P45, DEATH DOMAIN, APOPTOSIS, P75, NOGO, FADD
2ibz:C (ASN57) to (ALA83) YEAST CYTOCHROME BC1 COMPLEX WITH STIGMATELLIN | MULTISUBUNIT MEMBRANE PROTEIN COMPLEX, OXIDOREDUCTASE
3wa3:A (SER288) to (ALA308) CRYSTAL STRUCTURE OF COPPER AMINE OXIDASE FROM ARTHROBACTER GLOBIFORMIS IN N2 CONDITION | OXIDASE, COPPER BINDING, POST-TRANSLATIONALLY DERIVED QUINONE COFACTOR, CYTOPLASSM, OXIDOREDUCTASE
5aa5:E (PRO105) to (ALA152) ACTINOBACTERIAL-TYPE NIFE-HYDROGENASE FROM RALSTONIA EUTROPHA H16 AT 2.85 ANGSTROM RESOLUTION | OXIDOREDUCTASE, HYDROGENASE, DIHYDROGEN, METALLOENZYME, NICKEL, TROPOSPHERIC HYDROGEN, OXYGEN TOLERANCE
5aa5:G (PRO106) to (ALA155) ACTINOBACTERIAL-TYPE NIFE-HYDROGENASE FROM RALSTONIA EUTROPHA H16 AT 2.85 ANGSTROM RESOLUTION | OXIDOREDUCTASE, HYDROGENASE, DIHYDROGEN, METALLOENZYME, NICKEL, TROPOSPHERIC HYDROGEN, OXYGEN TOLERANCE
3wb8:C (GLY1497) to (LYS1544) CRYSTAL STRUCTURE OF MYOVA-GTD | HELIX BUNDLE, MOTOR PROTEIN
5abe:A (LYS489) to (GLN543) STRUCTURE OF GH84 WITH LIGAND | HYDROLASE, TIM-BARREL, INHIBITOR
5abe:B (LYS489) to (SER545) STRUCTURE OF GH84 WITH LIGAND | HYDROLASE, TIM-BARREL, INHIBITOR
5abg:A (LYS489) to (GLN543) STRUCTURE OF GH84 WITH LIGAND | HYDROLASE, GH84 GLYCOSIDE HYDROLASE, TIM-BARREL, INHIBITOR
5abg:B (LYS489) to (SER545) STRUCTURE OF GH84 WITH LIGAND | HYDROLASE, GH84 GLYCOSIDE HYDROLASE, TIM-BARREL, INHIBITOR
5abh:B (LYS489) to (SER545) STRUCTURE OF GH84 WITH LIGAND | HYDROLASE, TIM-BARREL, INHIBITOR
1us5:A (LEU272) to (GLY311) PUTATIVE GLUR0 LIGAND BINDING CORE WITH L-GLUTAMATE | RECEPTOR, MEMBRANE PROTEIN, GLUTAMATE RECEPTOR, GLUR0, L-GLUTAMATE, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS
3wcv:G (THR6) to (PHE51) THE STRUCTURE OF A DEOXYGENATED 400 KDA HEMOGLOBIN PROVIDES A MORE ACCURATE DESCRIPTION OF THE COOPERATIVE MECHANISM OF GIANT HEMOGLOBINS: CA BOUND FORM | GLOBIN FOLD, OXYGEN TRANSPORT, OXYGEN BINDING, BLOOD
2x02:B (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 AT 1.35 A RESOLUTION | CLASS D, HYDROLASE, ANTIBIOTIC RESISTANCE
2x01:B (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 S67A MUTANT AT PH 7 | HYDROLASE, ANTIBIOTIC RESISTANCE
2x0h:B (LYS489) to (SER545) BTGH84 MICHAELIS COMPLEX | GLYCOSIDE HYDROLASE, HYDROLASE, INHIBITOR, GLYCOSIDASE
3wej:A (SER37) to (PHE100) CRYSTAL STRUCTURE OF THE HUMAN SQUALENE SYNTHASE F288A MUTANT IN COMPLEX WITH PRESQUALENE PYROPHOSPHATE | FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE, HEAD-TO-HEAD SYNTHASES, CHOLESTEROL BIOSYNTHESIS, OXIDOREDUCTASE, TRANSFERASE
1iw7:D (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE RNA POLYMERASE HOLOENZYME FROM THERMUS THERMOPHILUS AT 2.6A RESOLUTION | RNA POLYMERASE HOLOENZYME, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
1iw7:N (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE RNA POLYMERASE HOLOENZYME FROM THERMUS THERMOPHILUS AT 2.6A RESOLUTION | RNA POLYMERASE HOLOENZYME, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
2x0y:A (PRO544) to (LEU598) SCREENING-BASED DISCOVERY OF DRUG-LIKE O-GLCNACASE INHIBITOR SCAFFOLDS | GLYCOSIDASE, HYDROLASE, CELL ADHESION
2ije:S (GLY1023) to (PRO1066) CRYSTAL STRUCTURE OF THE CDC25 DOMAIN OF RASGRF1 | RASGRF1, CDC25 DOMAIN, RAS GUANINE NUCLEOTIDE RELEASING FACTOR, RAS- SPECIFIC NUCLEOTIDE EXCHANGE FACTOR, SIGNALING PROTEIN
2ijn:A (SER478) to (LYS523) ISOTHIAZOLES AS ACTIVE-SITE INHIBITORS OF HCV NS5B POLYMERASE | HCV; NS5B; VIRAL RNA DIRECTED RNA POLYMERASE; RDRP; ACTIVE SITE; COVALENT INHIBITOR, TRANSCRIPTION,TRANSFERASE
2ijn:B (SER478) to (PHE526) ISOTHIAZOLES AS ACTIVE-SITE INHIBITORS OF HCV NS5B POLYMERASE | HCV; NS5B; VIRAL RNA DIRECTED RNA POLYMERASE; RDRP; ACTIVE SITE; COVALENT INHIBITOR, TRANSCRIPTION,TRANSFERASE
2x2e:A (THR274) to (GLY743) DYNAMIN GTPASE DIMER, LONG AXIS FORM | NITRATION, HYDROLASE, MEMBRANE FISSION, NUCLEOTIDE-BINDING, ENDOCYTOSIS, MOTOR PROTEIN
2iop:D (GLN10) to (GLU58) CRYSTAL STRUCTURE OF FULL-LENGTH HTPG, THE ESCHERICHIA COLI HSP90, BOUND TO ADP | HEAT SHOCK PROTEIN, CHAPERONE, HSP90
3wi3:A (SER214) to (VAL248) CRYSTAL STRUCTURE OF THE SLD3/TRESLIN DOMAIN FROM YEAST SLD3 | REPLICATION REGULATOR, CDC45-BINDING, ALPHA HELICAL
3wi3:A (ILE374) to (LYS418) CRYSTAL STRUCTURE OF THE SLD3/TRESLIN DOMAIN FROM YEAST SLD3 | REPLICATION REGULATOR, CDC45-BINDING, ALPHA HELICAL
3wi3:B (ILE374) to (GLY419) CRYSTAL STRUCTURE OF THE SLD3/TRESLIN DOMAIN FROM YEAST SLD3 | REPLICATION REGULATOR, CDC45-BINDING, ALPHA HELICAL
3wi3:C (ILE374) to (LYS418) CRYSTAL STRUCTURE OF THE SLD3/TRESLIN DOMAIN FROM YEAST SLD3 | REPLICATION REGULATOR, CDC45-BINDING, ALPHA HELICAL
5ait:B (GLN100) to (LEU146) A COMPLEX OF OF RNF4-RING DOMAIN, UBEV2, UBC13-UB (ISOPEPTIDE CROSSLINK) | LIGASE-SIGNALING PROTEIN COMPLEX, COMPLEX
4mia:A (SER478) to (PHE526) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH RG7109 (N-{4-[6-TERT-BUTYL-5-METHOXY-8-(6-METHOXY-2-OXO-2,5- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PHENYL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mia:B (SER478) to (ASN527) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH RG7109 (N-{4-[6-TERT-BUTYL-5-METHOXY-8-(6-METHOXY-2-OXO-2,5- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PHENYL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk8:A (SER478) to (LYS523) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 4 (N-(4-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]ETHYL}PHENYL)METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk8:B (SER478) to (LYS523) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 4 (N-(4-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]ETHYL}PHENYL)METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mk9:A (SER478) to (LYS523) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 12 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mka:A (SER478) to (LYS523) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 13 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mka:B (SER478) to (LYS523) HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 13 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE) | POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2iv2:X (THR477) to (THR516) REINTERPRETATION OF REDUCED FORM OF FORMATE DEHYDROGENASE H FROM E. COLI | OXIDOREDUCTASE, 4FE-4S, NAEROBIC, COMPLETE PROTEOME, DEHYDROGENASE, DIRECT PROTEIN SEQUENCING, FE4S4, FORMATE, IRON, IRON SULFUR CLUSTER, IRON-SULFUR, METAL-BINDING, MGD, MOLYBDENUM, MOLYBDOPTERIN, MOLYBDOPTERIN GUANINE DINUCLEOTIDE, MPT, NAD, SECYS, SELENIUM, SELENOCYSTEINE
2iwd:A (ARG452) to (MET515) OXACILLOYL-ACYLATED MECR1 EXTRACELLULAR ANTIBIOTIC-SENSOR DOMAIN. | BACTERIAL ANTIBIOTIC RESISTANCE, OXACILLIN, BETA-LACTAMASE, MRSA, ANTIBIOTIC RESISTANCE, METHICILLIN RESISTANCE, BETA- LACTAMIC ANTIBIOTICS, PENICILLIN-BINDING PROTEIN
1v9d:A (HIS1026) to (PHE1105) CRYSTAL STRUCTURE OF THE CORE FH2 DOMAIN OF MOUSE MDIA1 | HELIX BUNDLE, PROTEIN BINDING
1v9d:B (HIS1026) to (TYR1104) CRYSTAL STRUCTURE OF THE CORE FH2 DOMAIN OF MOUSE MDIA1 | HELIX BUNDLE, PROTEIN BINDING
1v9d:C (HIS1026) to (VAL1106) CRYSTAL STRUCTURE OF THE CORE FH2 DOMAIN OF MOUSE MDIA1 | HELIX BUNDLE, PROTEIN BINDING
1v9d:D (HIS1026) to (VAL1106) CRYSTAL STRUCTURE OF THE CORE FH2 DOMAIN OF MOUSE MDIA1 | HELIX BUNDLE, PROTEIN BINDING
3woj:A (TYR321) to (ALA388) CRYSTAL STRUCTURE OF THE DAP BII | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE
3wom:A (TYR321) to (ALA388) CRYSTAL STRUCTURE OF THE DAP BII DIPEPTIDE COMPLEX II | CHYMOTRYPSIN FOLD, HYDROLASE
3wom:B (ALA322) to (ALA388) CRYSTAL STRUCTURE OF THE DAP BII DIPEPTIDE COMPLEX II | CHYMOTRYPSIN FOLD, HYDROLASE
2j1d:G (ASP880) to (GLY961) CRYSTALLIZATION OF HDAAM1 C-TERMINAL FRAGMENT | ACTIN ASSEMBLY, PROTEIN BINDING
2xdl:A (TYR38) to (GLY73) STRUCTURE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND | CHAPERONE
4mqk:E (SER3) to (PRO44) CARBONMONOXY STRUCTURE OF THE HUMAN FETAL HEMOGLOBIN MUTANT HBF TOMS RIVER ALPHAWTGAMMAV67M | OXYGEN-TRANSPORT, AUTOOXIDATION, OXYGEN TRANSPORT
5are:H (THR99) to (LEU145) BOVINE MITOCHONDRIAL ATP SYNTHASE STATE 1B | HYDROLASE, ATP SYNTHASE, ROTARY ATPASE
4msx:A (VAL212) to (CYS258) CRYSTAL STRUCTURE OF AN ESSENTIAL YEAST SPLICING FACTOR | DEUBIQUITINASE, ZINC FINGER UBIQUITIN BINDING PROTEIN, ZNF-UBP, UBIQUITIN SPECIFIC PROTEASE, USP, PRE-MRNA SPLICING, SPLICEOSOME ASSEMBLY, PSEUDO-DEUBIQUITINASE, NUCLEAR, SPLICING
2xhu:B (SER478) to (ASN527) HCV-J4 NS5B POLYMERASE ORTHORHOMBIC CRYSTAL FORM | REPLICATION, TRANSCRIPTION, TRANSFERASE
1jqk:A (GLY480) to (ALA516) CRYSTAL STRUCTURE OF CARBON MONOXIDE DEHYDROGENASE FROM RHODOSPIRILLUM RUBRUM | ROSSMANN FOLD, OXIDOREDUCTASE
1jqk:B (GLY480) to (ALA516) CRYSTAL STRUCTURE OF CARBON MONOXIDE DEHYDROGENASE FROM RHODOSPIRILLUM RUBRUM | ROSSMANN FOLD, OXIDOREDUCTASE
1jqk:C (GLY480) to (GLY517) CRYSTAL STRUCTURE OF CARBON MONOXIDE DEHYDROGENASE FROM RHODOSPIRILLUM RUBRUM | ROSSMANN FOLD, OXIDOREDUCTASE
1jqk:D (GLY480) to (GLY517) CRYSTAL STRUCTURE OF CARBON MONOXIDE DEHYDROGENASE FROM RHODOSPIRILLUM RUBRUM | ROSSMANN FOLD, OXIDOREDUCTASE
1jqk:E (GLY480) to (GLY517) CRYSTAL STRUCTURE OF CARBON MONOXIDE DEHYDROGENASE FROM RHODOSPIRILLUM RUBRUM | ROSSMANN FOLD, OXIDOREDUCTASE
1jqk:F (GLY480) to (GLY517) CRYSTAL STRUCTURE OF CARBON MONOXIDE DEHYDROGENASE FROM RHODOSPIRILLUM RUBRUM | ROSSMANN FOLD, OXIDOREDUCTASE
3wxv:A (LEU305) to (ASP331) CRYSTAL STRUCTURE OF THE HUMAN ADIPONECTIN RECEPTOR 1 | PAQR FAMILY, ADIPONECTIN, OSMOTIN, APPL1, APPL2, MEMBRANE, MEMBRANE PROTEIN-IMMUNE SYSTEM COMPLEX
2xpk:A (PRO544) to (LEU598) CELL-PENETRANT, NANOMOLAR O-GLCNACASE INHIBITORS SELECTIVE AGAINST LYSOSOMAL HEXOSAMINIDASES | HYDROLASE, SIGNALLING
3j9j:A (SER5) to (VAL35) STRUCTURE OF THE CAPSAICIN RECEPTOR, TRPV1, DETERMINED BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY | ALPHA HELICAL, MEMBRANE PROTEIN
3j9j:B (SER5) to (VAL35) STRUCTURE OF THE CAPSAICIN RECEPTOR, TRPV1, DETERMINED BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY | ALPHA HELICAL, MEMBRANE PROTEIN
3j9j:C (SER5) to (VAL35) STRUCTURE OF THE CAPSAICIN RECEPTOR, TRPV1, DETERMINED BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY | ALPHA HELICAL, MEMBRANE PROTEIN
3j9j:D (SER5) to (VAL35) STRUCTURE OF THE CAPSAICIN RECEPTOR, TRPV1, DETERMINED BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY | ALPHA HELICAL, MEMBRANE PROTEIN
4n7o:I (GLY18) to (TYR42) CAPTURING THE HAEMOGLOBIN ALLOSTERIC TRANSITION IN A SINGLE CRYSTAL FORM; CRYSTAL STRUCTURE OF HALF-LIGANDED HUMAN HAEMOGLOBIN WITH PHOSPHATE AT 2.5 A RESOLUTION. | HYBRID HAEMOGLOBIN, ALLOSTERIC PATHWAY, TRANSPORT PROTEIN
4n7n:E (ASP6) to (PRO44) CAPTURING THE HAEMOGLOBIN ALLOSTERIC TRANSITION IN A SINGLE CRYSTAL FORM; CRYSTAL STRUCTURE OF FULL-LIGANDED HUMAN HAEMOGLOBIN WITH PHOSPHATE AT 2.75 A RESOLUTION. | HAEMOGLOBIN, ALLOSTERIC PATHWAY, TRANSPORT PROTEIN
4n7n:I (PRO4) to (PHE43) CAPTURING THE HAEMOGLOBIN ALLOSTERIC TRANSITION IN A SINGLE CRYSTAL FORM; CRYSTAL STRUCTURE OF FULL-LIGANDED HUMAN HAEMOGLOBIN WITH PHOSPHATE AT 2.75 A RESOLUTION. | HAEMOGLOBIN, ALLOSTERIC PATHWAY, TRANSPORT PROTEIN
2xwh:A (THR478) to (TYR524) HCV-J6 NS5B POLYMERASE STRUCTURE AT 1.8 ANGSTROM | TRANSFERASE, REPLICATION
2xxd:A (SER478) to (ARG523) HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 1.9 ANGSTROM | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
4ncj:D (GLN140) to (LEU163) CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSIS RAD50 R805E MUTATION WITH ADP BERYLLIUM FLOURIDE | ADENOSINE TRIPHOSPHATASE, DNA REPAIR, DNA BINDING PROTEIN, FUNGAL PROTEIN
2xym:A (SER478) to (ALA529) HCV-JFH1 NS5B T385A MUTANT | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
1k4e:A (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASES OXA-10 DETERMINED BY MAD PHASING WITH SELENOMETHIONINE | BETA-LACTAMASE, HYDROLASE, MAD PHASING, SELENOMETHIONINE, CARBAMYLATED LYSINE
1k4e:B (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASES OXA-10 DETERMINED BY MAD PHASING WITH SELENOMETHIONINE | BETA-LACTAMASE, HYDROLASE, MAD PHASING, SELENOMETHIONINE, CARBAMYLATED LYSINE
1k54:A (GLU129) to (VAL193) OXA-10 CLASS D BETA-LACTAMASE PARTIALLY ACYLATED WITH REACTED 6BETA- (1-HYDROXY-1-METHYLETHYL) PENICILLANIC ACID | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k54:B (GLU129) to (VAL193) OXA-10 CLASS D BETA-LACTAMASE PARTIALLY ACYLATED WITH REACTED 6BETA- (1-HYDROXY-1-METHYLETHYL) PENICILLANIC ACID | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k54:C (GLU129) to (VAL193) OXA-10 CLASS D BETA-LACTAMASE PARTIALLY ACYLATED WITH REACTED 6BETA- (1-HYDROXY-1-METHYLETHYL) PENICILLANIC ACID | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k54:D (GLU129) to (VAL193) OXA-10 CLASS D BETA-LACTAMASE PARTIALLY ACYLATED WITH REACTED 6BETA- (1-HYDROXY-1-METHYLETHYL) PENICILLANIC ACID | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k55:A (GLU129) to (VAL193) OXA 10 CLASS D BETA-LACTAMASE AT PH 7.5 | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k55:B (GLU129) to (VAL193) OXA 10 CLASS D BETA-LACTAMASE AT PH 7.5 | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k55:C (GLU129) to (VAL193) OXA 10 CLASS D BETA-LACTAMASE AT PH 7.5 | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k55:D (GLU129) to (VAL193) OXA 10 CLASS D BETA-LACTAMASE AT PH 7.5 | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k56:A (GLY128) to (VAL193) OXA 10 CLASS D BETA-LACTAMASE AT PH 6.5 | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k56:B (GLU129) to (VAL193) OXA 10 CLASS D BETA-LACTAMASE AT PH 6.5 | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k56:C (GLU129) to (VAL193) OXA 10 CLASS D BETA-LACTAMASE AT PH 6.5 | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k56:D (GLU129) to (VAL193) OXA 10 CLASS D BETA-LACTAMASE AT PH 6.5 | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k6s:A (GLU129) to (VAL193) STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH A PHENYLBORONIC ACID | BETA-LACTAMASE, INHIBITOR, PHENYLBORONIC ACID, HYDROLASE, CLASS D, CARBAMYLATED LYSINE
1k6s:B (VAL130) to (VAL193) STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH A PHENYLBORONIC ACID | BETA-LACTAMASE, INHIBITOR, PHENYLBORONIC ACID, HYDROLASE, CLASS D, CARBAMYLATED LYSINE
5bw9:H (LEU434) to (GLY474) CRYSTAL STRUCTURE OF YEAST V1-ATPASE IN THE AUTOINHIBITED FORM | HYDROLASE, AUTOINHIBITION
5bw9:h (LEU434) to (GLY474) CRYSTAL STRUCTURE OF YEAST V1-ATPASE IN THE AUTOINHIBITED FORM | HYDROLASE, AUTOINHIBITION
2jt8:A (ALA22) to (VAL64) SOLUTION STRUCTURE OF THE F153-TO-5-FLUROTRYPTOPHAN MUTANT OF HUMAN CARDIAC TROPONIN C | EF-HAND PROTEIN, CALCIUM-BIND PROTEIN, PHE-TO-TRP MUTATION, ACETYLATION, MUSCLE PROTEIN, POLYMORPHISM, STRUCTURAL PROTEIN
3zjy:B (ASP718) to (GLU757) CRYSTAL STRUCTURE OF IMPORTIN 13 - RANGTP - EIF1A COMPLEX | TRANSLATION, ACTIVE TRANSPORT, CELL NUCLEUS, NUCLEOCYTOPLASMIC TRANSPORT, MULTIPROTEIN COMPLEX, RNA-BINDING PROTEIN, RAN GTP-BINDING PROTEIN
4nho:A (LYS770) to (HIS798) STRUCTURE OF THE SPLICEOSOMAL DEAD-BOX PROTEIN PRP28 | DEAD-BOX, HELICASE, HYDROLASE
2kdc:A (GLY6) to (ILE44) NMR SOLUTION STRUCTURE OF E. COLI DIACYLGLYCEROL KINASE (DAGK) IN DPC MICELLES | MEMBRANE PROTEIN, SOLUTION NMR, KINASE, DAGK, CELL INNER MEMBRANE, CELL MEMBRANE, MEMBRANE, PHOSPHOLIPID BIOSYNTHESIS, TRANSFERASE, TRANSMEMBRANE
2kdc:B (GLY6) to (ILE44) NMR SOLUTION STRUCTURE OF E. COLI DIACYLGLYCEROL KINASE (DAGK) IN DPC MICELLES | MEMBRANE PROTEIN, SOLUTION NMR, KINASE, DAGK, CELL INNER MEMBRANE, CELL MEMBRANE, MEMBRANE, PHOSPHOLIPID BIOSYNTHESIS, TRANSFERASE, TRANSMEMBRANE
2kdc:C (GLY6) to (ILE44) NMR SOLUTION STRUCTURE OF E. COLI DIACYLGLYCEROL KINASE (DAGK) IN DPC MICELLES | MEMBRANE PROTEIN, SOLUTION NMR, KINASE, DAGK, CELL INNER MEMBRANE, CELL MEMBRANE, MEMBRANE, PHOSPHOLIPID BIOSYNTHESIS, TRANSFERASE, TRANSMEMBRANE
2kjh:A (THR100) to (ARG145) NMR BASED STRUCTURAL MODEL OF THE UBCH8-UBIQUITIN COMPLEX | PROTEIN-PROTEIN INTERACTION, HADDOCK MODEL, E2 ENZYME, ATP- BINDING, LIGASE, NUCLEOTIDE-BINDING, UBL CONJUGATION PATHWAY, CYTOPLASM, ISOPEPTIDE BOND, NUCLEUS, UBL CONJUGATION, LIGASE/PROTEIN BINDING COMPLEX
3zm9:A (THR371) to (LEU455) THE MECHANISM OF ALLOSTERIC COUPLING IN CHOLINE KINASE A1 REVEALED BY A RATIONALLY DESIGNED INHIBITOR | TRANSFERASE, NEGATIVE COOPERATIVITY, ALLOSTERIC MECHANISM, ELASTIC NETWORK ANALYSIS
4nld:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH BMS-791325 ALSO KNOWN AS (1AR,12BS)-8- CYCLOHEXYL-N-(DIMETHYLSULFAMOYL)-11-METHOXY-1A-{[(1R,5S)-3-METHYL-3, 8-DIAZABICYCLO[3.2.1]OCT-8-YL]CARBONYL}-1,1A,2,12B- TETRAHYDROCYCLOPROPA[D]INDOLO[2,1-A][2]BENZAZEPINE-5-CARBOXAMIDE AND 2-(4-FLUOROPHENYL)-N-METHYL-6-[(METHYLSULFONYL)AMINO]-5-(PROPAN-2- YLOXY)-1-BENZOFURAN-3-CARBOXAMIDE | NS5B, POLYMERASE, HCV, HEPATITIS C VIRUS, FINGERS, PALM, THUMB, TRANSFERASE/TRANSFERASE INHIBITOR, POLYMERASE/POLYMERASE INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5c0y:A (SER327) to (LYS398) CRYSTAL STRUCTURE OF THE RRP6 CATALYTIC DOMAIN BOUND TO POLY(U) RNA | EXORIBONUCLEASE, HYDROLASE, RNA PROCESSING AND DEGRADATION, NUCLEAR RNA EXOSOME
2lok:A (PRO5) to (PHE46) SOLUTION NMR STRUCTURE OF THE UNCHARACTERIZED PROTEIN FROM GENE LOCUS VNG_0733H OF HALOBACTERIUM SALINARIUM, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HSR50 | STRUCTURAL GENOMICS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, UNKNOWN FUNCTION
1wyn:A (ASP15) to (PRO61) SOLUTION STRUCTURE OF THE CH DOMAIN OF HUMAN CALPONIN-2 | CH DOMAIN, F-ACTIN BINDING, ALL ALPHA HELIX, STRUCTURAL GENOMICS, NPPSFA, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL PROTEIN
1kkc:A (LEU28) to (ASN94) CRYSTAL STRUCTURE OF ASPERGILLUS FUMIGATUS MNSOD | HOMOTETRAMER, OXIDOREDUCTASE
1kkc:X (LEU28) to (ASN94) CRYSTAL STRUCTURE OF ASPERGILLUS FUMIGATUS MNSOD | HOMOTETRAMER, OXIDOREDUCTASE
1kkc:Y (LEU28) to (LEU95) CRYSTAL STRUCTURE OF ASPERGILLUS FUMIGATUS MNSOD | HOMOTETRAMER, OXIDOREDUCTASE
2yb6:A (VAL102) to (TRP149) NATIVE HUMAN RAD6 | LIGASE, TRANSLESION SYNTHESIS, UBIQUITIN CHAIN SYNTHESIS
1kmi:Z (GLY15) to (MET136) CRYSTAL STRUCTURE OF AN E.COLI CHEMOTAXIS PROTEIN, CHEZ | FOUR-HELIX BUNDLE, SIGNALING PROTEIN
1wzv:B (THR100) to (ARG145) CRYSTAL STRUCTURE OF UBCH8 | UBIQUITIN, UBIQUITIN CONJUGATING ENZYME, E2, LIGASE
2ycy:A (TRP40) to (THR74) TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST CYANOPINDOLOL | GPCR, RECEPTOR, TRANSDUCER, ANTAGONIST BOUND FORM, INTEGRAL MEMBRANE PROTEIN, G-PROTEIN COUPLED RECEPTOR, THERMOSTABILISING POINT MUTATIONS, SEVEN-HELIX RECEPTOR, 7TM RECEPTOR
2ye2:A (TYR38) to (GLY73) HSP90 INHIBITORS AND DRUGS FROM FRAGMENT AND VIRTUAL SCREENING | PU3, ATPASE, CHAPERONE, STRESS RESPONSE, NUCLEOTIDE-BINDING, ATP-BINDING, PHOSPHOPROTEIN, PHOSPHORYLATION
2ye5:A (TYR38) to (GLY73) HSP90 INHIBITORS AND DRUGS FROM FRAGMENT AND VIRTUAL SCREENING | PU3, ATPASE, CHAPERONE, STRESS RESPONSE, NUCLEOTIDE-BINDING, ATP-BINDING, PHOSPHOPROTEIN, PHOSPHORYLATION
2yec:A (TYR38) to (GLY73) HSP90 INHIBITORS AND DRUGS FROM FRAGMENT AND VIRTUAL SCREENING | PU3, ATPASE, CHAPERONE, STRESS RESPONSE, NUCLEOTIDE-BINDING, ATP-BINDING, PHOSPHOPROTEIN, PHOSPHORYLATION
2yga:A (TYR24) to (GLU59) E88G-N92L MUTANT OF N-TERM HSP90 COMPLEXED WITH GELDANAMYCIN | CHAPERONE
2ygf:A (TYR24) to (PRO60) L89V, L93I AND V136M MUTANT OF N-TERM HSP90 COMPLEXED WITH GELDANAMYCIN | CHAPERONE
2yi6:A (TYR38) to (GLY73) STRUCTURAL CHARACTERIZATION OF 5-ARYL-4-(5-SUBSTITUTED-2- 4-DIHYDROXYPHENYL)-1,2,3-THIADIAZOLE HSP90 INHIBITORS. | CHAPERONE, ATPASE
2yi7:A (TYR38) to (GLY73) STRUCTURAL CHARACTERIZATION OF 5-ARYL-4-(5-SUBSTITUTED-2-4- DIHYDROXYPHENYL)-1,2,3-THIADIAZOLE HSP90 INHIBITORS. | CHAPERONE, ATPASE
2nn4:B (LEU11) to (GLN61) CRYSTAL STRUCTURE OF BACILLUS SUBTILIS YQGQ, PFAM DUF910 | NOVEL FOLD, PFAM:DUF910, 10278A, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, UNKNOWN FUNCTION
4o1o:A (PRO696) to (HIS723) CRYSTAL STRUCTURE OF RNASE L IN COMPLEX WITH 2-5A | ANKYRIN REPEAT-KINASE-RNASE, 2-5A, TRANSFERASE, TRANSFERASE,HYDROLASE
4o1o:B (PRO696) to (HIS723) CRYSTAL STRUCTURE OF RNASE L IN COMPLEX WITH 2-5A | ANKYRIN REPEAT-KINASE-RNASE, 2-5A, TRANSFERASE, TRANSFERASE,HYDROLASE
4o1o:C (PRO696) to (HIS723) CRYSTAL STRUCTURE OF RNASE L IN COMPLEX WITH 2-5A | ANKYRIN REPEAT-KINASE-RNASE, 2-5A, TRANSFERASE, TRANSFERASE,HYDROLASE
4o1o:D (PRO696) to (HIS723) CRYSTAL STRUCTURE OF RNASE L IN COMPLEX WITH 2-5A | ANKYRIN REPEAT-KINASE-RNASE, 2-5A, TRANSFERASE, TRANSFERASE,HYDROLASE
2ykb:A (TYR38) to (GLY73) TRICYCLIC SERIES OF HSP90 INHIBITORS | CHAPERONE, INHIBITION
2nqx:A (GLU196) to (LEU283) CRYSTAL STRUCTURE OF BOVINE LACTOPEROXIDASE WITH IODIDE IONS AT 2.9A RESOLUTION | LACTOPEROXIDASE, CRYSTAL STRUCTURES, COMPLEX, IODIDE ION, OXIDOREDUCTASE
4a0c:E (GLU538) to (PHE594) STRUCTURE OF THE CAND1-CUL4B-RBX1 COMPLEX | TRANSCRIPTION, LIGASE, UBIQUITIN, CELL CYCLE, DNA DAMAGE REPAIR
1l5j:B (ALA39) to (GLY74) CRYSTAL STRUCTURE OF E. COLI ACONITASE B. | MOLECULAR RECOGNITION, RNA BINDING, CITRIC ACID CYCLE, HEAT- LIKE DOMAIN, LYASE
4a0l:H (GLU538) to (PHE594) STRUCTURE OF DDB1-DDB2-CUL4B-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX | LIGASE-DNA-BINDING PROTEIN-DNA COMPLEX
4o8f:B (LEU423) to (LYS474) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN PPARGAMMA MUTANT R357A AND ROSIGLITAZONE | BUNDLE OF ALPHA-HELICES, SMALL FOUR-STRANDED BETA-SHEET, TRANSCRIPTION FACTOR, RXRALPHA, TRANSCRIPTION-TRANSCRIPTION INHIBITOR COMPLEX
3jvz:B (ILE99) to (LYS144) E2~UBIQUITIN-HECT | UBIQUITIN, HECT, E3, UBIQUITIN LIGASE, UBCH5B, NEDD4L, NEDD4-2, LIGASE, UBL CONJUGATION PATHWAY, HOST-VIRUS INTERACTION, LIGASE- SIGNALING PROTEIN COMPLEX
2yoj:B (SER478) to (ARG523) HCV NS5B POLYMERASE COMPLEXED WITH PYRIDONYLINDOLE COMPOUND | TRANSFERASE, INHIBITOR
5cfq:A (ALA195) to (LYS227) CRYSTAL STRUCTURE OF ANEMONE STING (NEMATOSTELLA VECTENSIS) IN COMPLEX WITH 2',3' CGAMP, C[G(2',5')PA(3',5')P] | STING, CYCLIC-DINUCLEOTIDE BINDING DOMAIN, IMMUNE SYSTEM
4oay:A (ARG125) to (ARG159) BLDD CTD-C-DI-GMP COMPLEX | BLDD, SMALL MOLECULE DIMERIZER, DNA BINDING PROTEIN
5cht:A (PRO117) to (PHE165) CRYSTAL STRUCTURE OF USP18 | UBIQUITIN-SPECIFIC PROTEASE, ISG15, INTERFERON, HYDROLASE
5cht:B (PRO117) to (PHE165) CRYSTAL STRUCTURE OF USP18 | UBIQUITIN-SPECIFIC PROTEASE, ISG15, INTERFERON, HYDROLASE
5chv:A (THR118) to (PHE165) CRYSTAL STRUCTURE OF USP18-ISG15 COMPLEX | UBIQUITIN-SPECIFIC PROTEASE, ISG15, INTERFERON, HYDROLASE
5chv:B (THR118) to (PHE165) CRYSTAL STRUCTURE OF USP18-ISG15 COMPLEX | UBIQUITIN-SPECIFIC PROTEASE, ISG15, INTERFERON, HYDROLASE
4odc:B (THR4) to (HIS41) CRYSTAL STRUCTURE OF TREMATOMUS BERNACCHII HEMOGLOBIN IN A PARTIALLY CYANIDED STATE | ALPHA PROTEIN, GLOBIN FOLD, OXYGEN TRANSPORT, OXYGEN TRANSPORT- PROTEIN BINDING COMPLEX
5ckv:B (ASP165) to (GLY232) DAHP SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS, FULLY INHIBITED BY TYROSINE, PHENYLALANINE, AND TRYPTOPHAN | TIM-BARREL, SHIKIMATE PATHWAY, FEEDBACK INHIBITION, TRANSFERASE
3k4w:J (ALA12) to (LYS45) CRYSTAL STRUCTURE OF UNCHARACTERIZED TIM-BARREL PROTEIN BB4693 FROM BORDETELLA BRONCHISEPTICA | STRUCTURAL GENOMICS, CRYSTAL STRUCTURE,PROTEIN STRUCTURE INITIATIVE, NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM, NYSGXRC, HYDROLASE, UNKNOWN FUNCTION, PSI-2, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS
1ln6:A (ALA153) to (ASN199) STRUCTURE OF BOVINE RHODOPSIN (METARHODOPSIN II) | G-PROTEIN COUPLED RECEPTOR, METARHODOPSIN II, RHODOPSIN, MEMBRANE PROTEIN
2o26:B (SER41) to (ALA94) STRUCTURE OF A CLASS III RTK SIGNALING ASSEMBLY | STEM CELL FACTOR, RECEPTOR TYROSINE KINASE, CLASS III, RECEPTOR- LIGAND COMPLEX, GROWTH FACTOR, CYTOKINE, 4-HELIX BUNDLE, CYTOKINE- SIGNALING PROTEIN COMPLEX
2o26:E (SER41) to (ALA94) STRUCTURE OF A CLASS III RTK SIGNALING ASSEMBLY | STEM CELL FACTOR, RECEPTOR TYROSINE KINASE, CLASS III, RECEPTOR- LIGAND COMPLEX, GROWTH FACTOR, CYTOKINE, 4-HELIX BUNDLE, CYTOKINE- SIGNALING PROTEIN COMPLEX
2o26:F (SER41) to (ALA94) STRUCTURE OF A CLASS III RTK SIGNALING ASSEMBLY | STEM CELL FACTOR, RECEPTOR TYROSINE KINASE, CLASS III, RECEPTOR- LIGAND COMPLEX, GROWTH FACTOR, CYTOKINE, 4-HELIX BUNDLE, CYTOKINE- SIGNALING PROTEIN COMPLEX
2o25:C (THR108) to (PHE155) UBIQUITIN-CONJUGATING ENZYME E2-25 KDA COMPLEXED WITH SUMO-1- CONJUGATING ENZYME UBC9 | LIGASE; UBL CONJUGATION PATHWAY, STRUCTURAL GENOMICS CONSORTIUM, SGC, LIGASE
4oin:D (GLU459) to (ASP504) CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS TRANSCRIPTION INITIATION COMPLEX SOAKED WITH GE23077 | GE23077, TRANSCRIPTION INHIBITOR, TRANSCRIPTION OPEN COMPLEX, TRANSCRIPTION INITIATION COMPLEX, I SITE, I+1 SITE, RNA POLYMERASE, DNA/RNA/NTP BINDING, POLYMERIZATION OF RIBONUCLEOTIDES, NUCLEOID, TRANSCRIPTION, TRANSFERASE-ANTIBIOTIC COMPLEX
2z6e:A (ILE881) to (GLY961) CRYSTAL STRUCTURE OF HUMAN DAAM1 FH2 | COILED COIL, ALTERNATIVE SPLICING, CYTOPLASM, PROTEIN FIBRIL REGULATOR
2z6e:B (ASP880) to (GLY961) CRYSTAL STRUCTURE OF HUMAN DAAM1 FH2 | COILED COIL, ALTERNATIVE SPLICING, CYTOPLASM, PROTEIN FIBRIL REGULATOR
2z6e:C (ASP880) to (GLY961) CRYSTAL STRUCTURE OF HUMAN DAAM1 FH2 | COILED COIL, ALTERNATIVE SPLICING, CYTOPLASM, PROTEIN FIBRIL REGULATOR
2z6e:D (ASP880) to (GLY961) CRYSTAL STRUCTURE OF HUMAN DAAM1 FH2 | COILED COIL, ALTERNATIVE SPLICING, CYTOPLASM, PROTEIN FIBRIL REGULATOR
1xls:G (GLN119) to (MET153) CRYSTAL STRUCTURE OF THE MOUSE CAR/RXR LBD HETERODIMER BOUND TO TCPOBOP AND 9CRA AND A TIF2 PEPTIDE CONTAING THE THIRD LXXLL MOTIFS | LBD, NUCLEAR RECEPTOR, CAR, XENOBIOTIC, TRANSCRIPTION
2zc7:C (LYS99) to (LEU161) CRYSTAL STRUCTURE OF CLASS C BETA-LACTAMASE ACT-1 | TWO-DOMAIN STRUCTURE, HYDROLASE
3k97:A (TYR38) to (GLY73) HSP90 N-TERMINAL DOMAIN IN COMPLEX WITH 4-CHLORO-6-{[(2R)-2- (2-METHYLPHENYL)PYRROLIDIN-1-YL]CARBONYL}BENZENE-1,3-DIOL | HSP90, ATP BINDING DOMAIN, N-TERMINAL DOMAIN, INHIBITION, ACETYLATION, ALTERNATIVE SPLICING, ATP-BINDING, CHAPERONE, CYTOPLASM, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, STRESS RESPONSE
4a8f:B (SER582) to (SER638) NON-CATALYTIC IONS DIRECT THE RNA-DEPENDENT RNA POLYMERASE OF BACTERIAL DSRNA VIRUS PHI6 FROM DE NOVO INITIATION TO ELONGATION | TRANSFERASE, TRANSLATION
3kae:A (VAL203) to (ARG236) CDC27 N-TERMINUS | TETRATRICOPEPTIDE REPEAT PROTEIN, PROTEIN BINDING
3kae:B (VAL203) to (ARG236) CDC27 N-TERMINUS | TETRATRICOPEPTIDE REPEAT PROTEIN, PROTEIN BINDING
3kae:C (VAL203) to (ARG236) CDC27 N-TERMINUS | TETRATRICOPEPTIDE REPEAT PROTEIN, PROTEIN BINDING
1xqs:A (GLU312) to (THR347) CRYSTAL STRUCTURE OF THE HSPBP1 CORE DOMAIN COMPLEXED WITH THE FRAGMENT OF HSP70 ATPASE DOMAIN | ARMADILLO REPEAT, SUPERHELICAL TWIST, CHAPERONE
1xqs:B (GLU312) to (SER350) CRYSTAL STRUCTURE OF THE HSPBP1 CORE DOMAIN COMPLEXED WITH THE FRAGMENT OF HSP70 ATPASE DOMAIN | ARMADILLO REPEAT, SUPERHELICAL TWIST, CHAPERONE
5ctm:A (GLU163) to (VAL227) STRUCTURE OF BPU1 BETA-LACTAMASE | HYDROLASE, BETA-LACTAMASE
5ctn:A (GLY162) to (VAL227) STRUCTURE OF BPU1 BETA-LACTAMASE | HYDROLASE, BETA-LACTAMASE
2zj2:A (GLU586) to (TYR639) ARCHAEAL DNA HELICASE HJM APO STATE IN FORM 1 | RECA FOLD, ATP-BINDING, HELICASE, HYDROLASE, NUCLEOTIDE- BINDING
4oog:C (ASN289) to (GLN357) CRYSTAL STRUCTURE OF YEAST RNASE III (RNT1P) COMPLEXED WITH THE PRODUCT OF DSRNA PROCESSING | RNASE:RNA COMPLEX, RIBONUCLEASE III DOMAIN, DOUBLE-STRANDED RNA- BINDING DOMAIN, ENDORIBONUCLEASE, DSRNA-SPECIFIC RNASE, DOUBLE- STRANDED RNA, HYDROLASE-RNA COMPLEX
2zj5:A (SER531) to (GLU591) ARCHAEAL DNA HELICASE HJM COMPLEXED WITH ADP IN FORM 1 | RECA FOLD, ATP-BINDING, HELICASE, HYDROLASE, NUCLEOTIDE- BINDING
2zja:A (PRO585) to (TYR639) ARCHAEAL DNA HELICASE HJM COMPLEXED WITH AMPPCP IN FORM 2 | RECA FOLD, ATP-BINDING, HELICASE, HYDROLASE, NUCLEOTIDE- BINDING
4aaa:A (ALA182) to (ASN230) CRYSTAL STRUCTURE OF THE HUMAN CDKL2 KINASE DOMAIN | TRANSFERASE, PHOSPHO-MIMETIC
2zku:A (SER478) to (TYR524) STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM | HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE
2zku:B (SER478) to (LYS523) STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM | HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE
2zku:C (SER478) to (LYS523) STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM | HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE
2zku:D (SER478) to (LYS523) STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM | HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE
2zlw:A (SER3) to (PHE43) HORSE METHEMOGLOBIN HIGH SALT, PH 7.0 (75% RELATIVE HUMIDITY) | PROTEIN HYDRATION, ALLOSTERIC TRANSITIONS, VARIABILITY IN QUATERNARY STRUCTURE, SOLVENT CONTENT AND CRYSTAL STRUCTURE, WATER-MEDIATED TRANSFORMATION, HEME, IRON, METAL-BINDING, OXYGEN TRANSPORT, POLYMORPHISM, TRANSPORT, OXYGEN STORAGE
1mas:A (GLY190) to (ARG233) PURINE NUCLEOSIDE HYDROLASE | HYDROLASE, PURINE NUCLEOSIDE HYDROLASE, PURINE NUCLEOSIDASE, IU-NH
1mas:B (GLY190) to (SER231) PURINE NUCLEOSIDE HYDROLASE | HYDROLASE, PURINE NUCLEOSIDE HYDROLASE, PURINE NUCLEOSIDASE, IU-NH
3kii:B (SER288) to (ALA308) AGAO 5-PHENOXY-2,3-PENTADIENYLAMINE COMPLEX | CUAO, AMINE OXIDASE, ARTHROBACTER GLOBIFORMIS, COPPER CONTAINING, METAL-BINDING, OXIDOREDUCTASE, TPQ, QUINONE, INHIBITION, 5-PHENOXY- 2,3-PENTADIENYLAMINE, DISULFIDE BOND
4acq:B (VAL1193) to (GLN1241) ALPHA-2 MACROGLOBULIN | HYDROLASE INHIBITOR, PROTEINASE INHIBITOR, IRREVERSIBLE PROTEINASE INHIBITOR, CONFORMATIONAL CHANGE, BLOOD PLASMA INHIBITOR
4acq:C (VAL1193) to (GLN1241) ALPHA-2 MACROGLOBULIN | HYDROLASE INHIBITOR, PROTEINASE INHIBITOR, IRREVERSIBLE PROTEINASE INHIBITOR, CONFORMATIONAL CHANGE, BLOOD PLASMA INHIBITOR
4acq:D (VAL1193) to (GLN1241) ALPHA-2 MACROGLOBULIN | HYDROLASE INHIBITOR, PROTEINASE INHIBITOR, IRREVERSIBLE PROTEINASE INHIBITOR, CONFORMATIONAL CHANGE, BLOOD PLASMA INHIBITOR
4acr:A (CYS32) to (ASN137) CRYSTAL STRUCTURE OF N-GLYCOSYLATED, C-TERMINALLY TRUNCATED HUMAN GLYPICAN-1 | PROTEOGLYCAN, GLYCOSAMINOGLYCANS, HEPARAN SULFATE, HELICAL BUNDLE, GLYCOPROTEIN, MEMBRANE PROTEIN
4acr:C (GLY33) to (ALA138) CRYSTAL STRUCTURE OF N-GLYCOSYLATED, C-TERMINALLY TRUNCATED HUMAN GLYPICAN-1 | PROTEOGLYCAN, GLYCOSAMINOGLYCANS, HEPARAN SULFATE, HELICAL BUNDLE, GLYCOPROTEIN, MEMBRANE PROTEIN
4oys:A (ASP388) to (GLY414) CRYSTAL STRUCTURE OF VPS34 IN COMPLEX WITH SAR405. | LIPID KINASE
4adp:A (THR478) to (ASN527) HCV-J6 NS5B POLYMERASE V405I MUTANT | HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, TRANSFERASE, RNA-DIRECTED RNA POLYMERASE, RDRP, DE NOVO INITIATION, PRIMING
4ozv:A (ALA285) to (SER362) CRYSTAL STRUCTURE OF THE PERIPLASMIC ALGINATE LYASE ALGL | ALGL, PSEUDOMONAS AERUGINOSA, ALGINATE, ALGINATE LYASE, POLYSACCHARIDE, ALPHA/ALPHA TOROID
4aex:A (SER478) to (ALA529) HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 2.4 ANGSTROM IN A PRIMITIVE ORTHORHOMBIC SPACE GROUP | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
4aex:B (HIS479) to (ARG523) HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 2.4 ANGSTROM IN A PRIMITIVE ORTHORHOMBIC SPACE GROUP | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
5d1v:A (THR5) to (PHE37) CRYSTAL STRUCTURE AND THERMAL STABILITY OF HEMOGLOBIN FROM THERMOPHILIC PHOTOTROPHIC BACTERIUM CHLOROFLEXUS AURANTIACUS | TRUNCATED HEMOGLOBIN, TEMPERATURE STABILITY, OXYGEN TRANSPORT
5d1v:B (THR5) to (PHE37) CRYSTAL STRUCTURE AND THERMAL STABILITY OF HEMOGLOBIN FROM THERMOPHILIC PHOTOTROPHIC BACTERIUM CHLOROFLEXUS AURANTIACUS | TRUNCATED HEMOGLOBIN, TEMPERATURE STABILITY, OXYGEN TRANSPORT
4ags:C (ARG198) to (ALA228) LEISHMANIA TDR1 - A UNIQUE TRIMERIC GLUTATHIONE TRANSFERASE | TRANSFERASE, LEISHMANIASIS, DE-GLUATHIONYLATION
4agu:A (PRO182) to (ASN232) CRYSTAL STRUCTURE OF THE HUMAN CDKL1 KINASE DOMAIN | TRANSFERASE, PHOSPHO-MIMETIC, KINASE
4agu:B (PRO182) to (ASN232) CRYSTAL STRUCTURE OF THE HUMAN CDKL1 KINASE DOMAIN | TRANSFERASE, PHOSPHO-MIMETIC, KINASE
4agu:C (PRO182) to (ASN232) CRYSTAL STRUCTURE OF THE HUMAN CDKL1 KINASE DOMAIN | TRANSFERASE, PHOSPHO-MIMETIC, KINASE
4p5o:I (ILE125) to (GLY170) STRUCTURE OF AN RBX1-UBC12~NEDD8-CUL1-DCN1 COMPLEX: A RING-E3- E2~UBIQUITIN-LIKE PROTEIN-SUBSTRATE INTERMEDIATE TRAPPED IN ACTION | NEDD8, CULLIN, NEDDYLATION, COMPLEX, UBC12, DCN1, UBIQUITIN, LIGASE
4p5o:F (SER118) to (ASN167) STRUCTURE OF AN RBX1-UBC12~NEDD8-CUL1-DCN1 COMPLEX: A RING-E3- E2~UBIQUITIN-LIKE PROTEIN-SUBSTRATE INTERMEDIATE TRAPPED IN ACTION | NEDD8, CULLIN, NEDDYLATION, COMPLEX, UBC12, DCN1, UBIQUITIN, LIGASE
4p5o:G (ILE125) to (GLY170) STRUCTURE OF AN RBX1-UBC12~NEDD8-CUL1-DCN1 COMPLEX: A RING-E3- E2~UBIQUITIN-LIKE PROTEIN-SUBSTRATE INTERMEDIATE TRAPPED IN ACTION | NEDD8, CULLIN, NEDDYLATION, COMPLEX, UBC12, DCN1, UBIQUITIN, LIGASE
3a0r:A (THR520) to (GLU600) CRYSTAL STRUCTURE OF HISTIDINE KINASE THKA (TM1359) IN COMPLEX WITH RESPONSE REGULATOR PROTEIN TRRA (TM1360) | FOUR HELIX BUNDLE, PAS FOLD, KINASE, PHOSPHOPROTEIN, TRANSFERASE, TWO-COMPONENT REGULATORY SYSTEM
3kpw:A (ALA24) to (PRO50) CRYSTAL STRUCTURE OF HPNMT IN COMPLEX ADOHCY AND 1-AMINOISOQUINOLINE | METHYLTRANSFERASE, FRAGMENT SCREENING, CATECHOLAMINE BIOSYNTHESIS, S- ADENOSYL-L-METHIONINE, TRANSFERASE
3kpy:A (ALA24) to (PRO50) CRYSTAL STRUCTURE OF HPNMT IN COMPLEX ADOHCY AND 6-CHLOROOXINDOLE | METHYLTRANSFERASE, FRAGMENT SCREENING, CATECHOLAMINE BIOSYNTHESIS, S- ADENOSYL-L-METHIONINE, TRANSFERASE
3kqm:A (ALA24) to (PRO50) CRYSTAL STRUCTURE OF HPNMT IN COMPLEX ADOHCY AND 4-BROMO-1H-IMIDAZOLE | METHYLTRANSFERASE, FRAGMENT SCREENING, CATECHOLAMINE BIOSYNTHESIS, S- ADENOSYL-L-METHIONINE, TRANSFERASE
3kqq:A (ALA24) to (PRO50) CRYSTAL STRUCTURE OF HPNMT IN COMPLEX ADOHCY AND 2-HYDROXYNICOTINIC ACID | METHYLTRANSFERASE, FRAGMENT SCREENING, CATECHOLAMINE BIOSYNTHESIS, S- ADENOSYL-L-METHIONINE, TRANSFERASE
3kqw:A (ALA24) to (PRO50) CRYSTAL STRUCTURE OF HPNMT IN COMPLEX ADOHCY AND 5-CHLOROBENZIMIDAZOLE | METHYLTRANSFERASE, FRAGMENT SCREENING, CATECHOLAMINE BIOSYNTHESIS, S- ADENOSYL-L-METHIONINE, TRANSFERASE
1yen:C (PRO4) to (PRO44) T-TO-T(HIGH) QUATERNARY TRANSITIONS IN HUMAN HEMOGLOBIN: BETAP36A OXY (2MM IHP, 20% PEG) (10 TEST SETS) | HEMOGLOBIN MUTANT, GLOBIN, TRANSPORT PROTEIN
3a5y:D (SER148) to (VAL181) CRYSTAL STRUCTURE OF GENX FROM ESCHERICHIA COLI IN COMPLEX WITH LYSYLADENYLATE ANALOG | AMINOACYL-TRNA SYNTHETASE PARALOG, TRANSLATION, TRNA, LYSYL-TRNA SYNTHETASE, LYSYLADENYLATE ANALOG, AMINOACYL-TRNA SYNTHETASE, LIGASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
3a5z:A (SER148) to (GLU185) CRYSTAL STRUCTURE OF ESCHERICHIA COLI GENX IN COMPLEX WITH ELONGATION FACTOR P | AMINOACYL-TRNA SYNTHETASE PARALOG, TRANSLATION, TRNA, LYSYL-TRNA SYNTHETASE, ELONGATION FACTOR, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, AMINOACYL-TRNA SYNTHETASE, LIGASE
3kvb:A (THR390) to (LYS444) STRUCTURE OF KIAA1718 JUMONJI DOMAIN IN COMPLEX WITH N- OXALYLGLYCINE | JUMONJI DOMAIN LYSINE DEMETHYLASE, METAL-BINDING, IRON, NICKEL ION
1n0j:A (LEU14) to (ASN80) THE STRUCTURE OF HUMAN MITOCHONDRIAL MN3+ SUPEROXIDE DISMUTASE REVEALS A NOVEL TETRAMERIC INTERFACE OF TWO 4-HELIX BUNDLES | FOUR-HELIX BUNDLE, METALLOENZYME, MANGANESE, OXIDOREDUCTASE
1ymp:B (ARG107) to (HIS141) THE CRYSTAL STRUCTURE OF A PARTIAL MOUSE NOTCH-1 ANKYRIN DOMAIN: REPEATS 4 THROUGH 7 PRESERVE AN ANKYRIN FOLD | ANKYRIN REPEATS, HELIX-TURN-HELIX, TRANSCRIPTION
1ynj:D (ALA458) to (ASP504) TAQ RNA POLYMERASE-SORANGICIN COMPLEX | TRANSFERASE
1ynn:D (GLY457) to (ASP504) TAQ RNA POLYMERASE-RIFAMPICIN COMPLEX | TRANSFERASE, RNA POLYMERASE, RIFAMPICIN
3l0i:A (PRO318) to (ASN383) COMPLEX STRUCTURE OF SIDM/DRRA WITH THE WILD TYPE RAB1 | GEF-GDF-RAB COMPLEX, GTP-BINDING, GUANINE-NUCLEOTIDE EXCHANGE FACTOR, GDI-DISPLACEMENT FACTOR, TYPE IV EFFECTOR PROTEIN FROM LEGIONELLA, PROTEIN BINDING-PROTEIN TRANSPORT COMPLEX
4pj3:A (ARG894) to (PHE968) STRUCTURAL INSIGHT INTO THE FUNCTION AND EVOLUTION OF THE SPLICEOSOMAL HELICASE AQUARIUS, STRUCTURE OF AQUARIUS IN COMPLEX WITH AMPPNP | RNA HELICASE, PRE-MRNA SPLICING, RNA BINDING PROTEIN
1yt3:A (PHE118) to (GLN191) CRYSTAL STRUCTURE OF ESCHERICHIA COLI RNASE D, AN EXORIBONUCLEASE INVOLVED IN STRUCTURED RNA PROCESSING | RNASE; EXORIBONUCLEASE; RIBONUCLEASE; EXONUCLEASE; NUCLEASE; HYDROLASE; TRNA PROCESSING, HYDROLASE,TRANSLATION
5dir:A (ALA57) to (GLY120) MEMBRANE PROTEIN AT 2.8 ANGSTROMS | MEMBRANE PROTEIN, PROTEASE, ANTIBIOTIC, COMPLEX, HYDROLASE
1yuy:A (THR478) to (TYR524) HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2A | NS5B POLYMERASE GENOTYPE 2A, VIRAL PROTEIN
1yv2:A (THR478) to (ARG523) HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2A | NS5B POLYMERASE GENOTYPE 2A, TRANSFERASE
1yvz:A (THR478) to (PHE526) HEPATITIS C VIRUS RNA POLYMERASE GENOTYPE 2A IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | NS5B POLYMERASE GENOTYPE 2A, NON-NUCLEOSIDE INHIBITOR, VIRAL PROTEIN
3l8a:A (GLU200) to (PHE225) CRYSTAL STRUCTURE OF METC FROM STREPTOCOCCUS MUTANS | METC, SMU.1674, BETA-CYSTATHIONASE, STREPTOCOCCUS MUTANS, AMINOTRANSFERASE, LYASE, TRANSFERASE
3l8a:B (GLU200) to (PHE225) CRYSTAL STRUCTURE OF METC FROM STREPTOCOCCUS MUTANS | METC, SMU.1674, BETA-CYSTATHIONASE, STREPTOCOCCUS MUTANS, AMINOTRANSFERASE, LYASE, TRANSFERASE
4pnx:A (GLU196) to (LEU283) CRYSTAL STRUCTURE OF THE COMPLEX OF LACTOPEROXIDASE WITH BROMO METHANE AT 2.41 ANGSTROM RESOLUTION | OXIDOREDUCTASE
1z3d:A (ASP101) to (PHE152) PROTEIN CRYSTAL GROWTH IMPROVEMENT LEADING TO THE 2.5A CRYSTALLOGRAPHIC STRUCTURE OF UBIQUITIN-CONJUGATING ENZYME (UBC-1) FROM CAENORHABDITIS ELEGANS | E2, UBIQUITINATION, UBIQUITIN-CONJUGATING, CRYSTAL GROWTH, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, SOUTHEAST COLLABORATORY FOR STRUCTURAL GENOMICS, SECSG, LIGASE
5dny:D (GLN134) to (GLY157) STRUCTURE OF THE ATPRS-MRE11/RAD50-DNA COMPLEX | NUCLEASE, RECOMBINATION-DNA COMPLEX
5doq:A (ASP170) to (GLU247) THE STRUCTURE OF BD OXIDASE FROM GEOBACILLUS THERMODENITRIFICANS | BD OXIDASE, TERMINAL OXIDASE, OXIDOREDUCTASE
1z67:A (GLY17) to (SER53) STRUCTURE OF HOMEODOMAIN-LIKE PROTEIN OF UNKNOWN FUNCTION S4005 FROM SHIGELLA FLEXNERI | STRUCTURAL GENOMICS, HYPOTHETICAL PROTEIN, SHIGELLA FLEXNERI, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
3lce:B (MET132) to (VAL193) CRYSTAL STRUCTURE OF OXA-10 BETA-LACTAMASE COVALENTLY BOUND TO CYCLOBUTANONE BETA-LACTAM MIMIC | BETA-LACTAMASE, BETA-LACTAMASE INHIBITOR, BETA-LACTAM MIMIC, CYCLOBUTANONE, HEMIKETAL, ANTIBIOTIC RESISTANCE, DISULFIDE BOND, HYDROLASE, PLASMID, TRANSPOSABLE ELEMENT
3lce:C (GLU129) to (VAL193) CRYSTAL STRUCTURE OF OXA-10 BETA-LACTAMASE COVALENTLY BOUND TO CYCLOBUTANONE BETA-LACTAM MIMIC | BETA-LACTAMASE, BETA-LACTAMASE INHIBITOR, BETA-LACTAM MIMIC, CYCLOBUTANONE, HEMIKETAL, ANTIBIOTIC RESISTANCE, DISULFIDE BOND, HYDROLASE, PLASMID, TRANSPOSABLE ELEMENT
3lce:D (GLY128) to (VAL193) CRYSTAL STRUCTURE OF OXA-10 BETA-LACTAMASE COVALENTLY BOUND TO CYCLOBUTANONE BETA-LACTAM MIMIC | BETA-LACTAMASE, BETA-LACTAMASE INHIBITOR, BETA-LACTAM MIMIC, CYCLOBUTANONE, HEMIKETAL, ANTIBIOTIC RESISTANCE, DISULFIDE BOND, HYDROLASE, PLASMID, TRANSPOSABLE ELEMENT
1z7h:A (GLY277) to (LYS329) 2.3 ANGSTROM CRYSTAL STRUCTURE OF TETANUS NEUROTOXIN LIGHT CHAIN | TENT, TETANUS, METALLOPROTEASE, SNARE, NEUROTRANSMISSION, HYDROLASE
1za0:A (TYR232) to (VAL273) X-RAY STRUCTURE OF PUTATIVE ACYL-ACP DESATURASE DESA2 FROM MYCOBACTERIUM TUBERCULOSIS H37RV | DESATURASE, FOUR-HELIX BUNDLE, METAL BINDING PROTEIN, OXIDOREDUCTASE
1zbo:B (ARG126) to (LEU183) X-RAY CRYSTAL STRUCTURE OF PROTEIN BPP1347 FROM BORDETELLA PARAPERTUSSIS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET BOR27. | ALPHA-BETA PROTEIN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
3lkh:B (SER478) to (ARG523) INHIBITORS OF HEPATITIS C VIRUS POLYMERASE: SYNTHESIS AND CHARACTERIZATION OF NOVEL 6-FLUORO-N-[2-HYDROXY-1(S)-BENZAMIDES | HCV, NS5B, POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST CELL MEMBRANE, HOST CYTOPLASM, HOST ENDOPLASMIC RETICULUM, HOST LIPID DROPLET, HOST MEMBRANE, HOST MITOCHONDRION, HOST NUCLEUS, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
1zkd:A (THR299) to (ARG334) X-RAY STRUCTURE OF THE PUTATIVE PROTEIN Q6N1P6 FROM RHODOPSEUDOMONAS PALUSTRIS AT THE RESOLUTION 2.1 A , NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET RPR58 | NESG, RPR58, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, UNKNOWN FUNCTION
1zkw:B (GLY256) to (TYR306) CRYSTAL STRUCTURE OF ARG347ALA MUTANT OF BOTULINUM NEUROTOXIN E CATALYTIC DOMAIN | BOTULINUM NEUROTOXIN E, ARG347ALA MUTANT, CATALYTIC DOMAIN, HYDROLASE
1zkx:A (GLY256) to (TYR306) CRYSTAL STRUCTURE OF GLU158ALA/THR159ALA/ASN160ALA- A TRIPLE MUTANT OF CLOSTRIDIUM BOTULINUM NEUROTOXIN E CATALYTIC DOMAIN | BOTULINUM NEUROTOXIN E, CATALYTIC DOMAIN, LIGHT CHAIN, GLU158ALA/THR159ALA/ASN160ALA MUTANT, HYDROLASE
1zkx:B (GLY256) to (TYR306) CRYSTAL STRUCTURE OF GLU158ALA/THR159ALA/ASN160ALA- A TRIPLE MUTANT OF CLOSTRIDIUM BOTULINUM NEUROTOXIN E CATALYTIC DOMAIN | BOTULINUM NEUROTOXIN E, CATALYTIC DOMAIN, LIGHT CHAIN, GLU158ALA/THR159ALA/ASN160ALA MUTANT, HYDROLASE
1zl6:A (GLY256) to (TYR306) CRYSTAL STRUCTURE OF TYR350ALA MUTANT OF CLOSTRIDIUM BOTULINUM NEUROTOXIN E CATALYTIC DOMAIN | BOTULINUM NEUROTOXIN E, CATALYTIC DOMAIN, LIGHT CHAIN, TYR350ALA MUTANT, HYDROLASE
1zl6:B (THR257) to (GLY307) CRYSTAL STRUCTURE OF TYR350ALA MUTANT OF CLOSTRIDIUM BOTULINUM NEUROTOXIN E CATALYTIC DOMAIN | BOTULINUM NEUROTOXIN E, CATALYTIC DOMAIN, LIGHT CHAIN, TYR350ALA MUTANT, HYDROLASE
1zn3:B (GLY256) to (TYR306) CRYSTAL STRUCTURE OF GLU335ALA MUTANT OF CLOSTRIDIUM BOTULINUM NEUROTOXIN TYPE E | BOTULINUM NEUROTOXIN E, CATALYTIC DOMAIN, LIGHT CHAIN, GLU335ALA MUTANT, HYDROLASE
5dzr:A (PHE1043) to (ARG1095) STRUCTURE OF RNA HELICASE FRH A CRITICAL COMPONENT OF THE NEUROSPORA CRASSA CIRCADIAN CLOCK | HELICASE, CIRCADIAN CLOCK, RNA BINDING PROTEIN, HYDROLASE
4q4z:D (GLU459) to (ASP504) THERMUS THERMOPHILUS RNA POLYMERASE DE NOVO TRANSCRIPTION INITIATION COMPLEX | TRANSCRIPTION, DNA AND NTP, TRANSCRIPTION-DNA COMPLEX
4q59:B (THR159) to (GLN213) CRYSTAL STRUCTURE OF PLECTIN 1A ACTIN-BINDING DOMAIN | CALPONIN HOMOLOGY DOMAIN, STRUCTURAL PROTEIN
3ls8:B (ASP389) to (GLY414) CRYSTAL STRUCTURE OF HUMAN PIK3C3 IN COMPLEX WITH 3-[4-(4- MORPHOLINYL)THIENO[3,2-D]PYRIMIDIN-2-YL]-PHENOL | ALPHA/BETA PROTEIN, PIK3C3, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3, COMPOUND 15E, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE, INHIBITOR, PHOSPHATIDYLINOSITOL
5e2l:B (ASP165) to (CYS231) 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH D-PHENYLALANINE | 3-DEOXY-7-PHOSPHOHEPTULOSONATE SYNTHASE, ALLOSTERIC REGULATION, ALLOSTERIC SITE, AMINO ACID, TRANSFERASE
5e3x:A (SER296) to (SER318) CRYSTAL STRUCTURE OF THERMOSTABLE CARBOXYPEPTIDASE (FISCP) FROM FERVIDOBACTERIUM ISLANDICUM AW-1 | CARBOXYPEPTIDASE, FERVIDOBACTERIUM, FISCP, HYDROLASE
5e40:A (ASP165) to (CYS231) 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS WITH D-TYROSINE BOUND IN THE PHENYLALANINE BINDING SITE | AMINO ACID, ALLOSTERIC REGULATION, SHIKIMATE PATHWAY, 3-DEOXY-D- ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE, TRANSFERASE
5e4v:A (GLY288) to (SER306) CRYSTAL STRUCTURE OF MEASLES N0-P COMPLEX | PARAMYXOVIRUS, NUCLEOCAPSID PROTEIN, RNA-BINDING PROTEIN, VIRAL PROTEIN
5e6i:I (HIS151) to (GLN180) CRYSTAL STRUCTURE OF TCR PF8 IN COMPLEX WITH FLU MP(58-66) EPITOPE PRESENTED BY HLA-A2 | IMMUNE SYSTEM, TCR, HLA-A2, FLU, COMPLEX
1zyr:N (ALA458) to (ASP504) STRUCTURE OF THERMUS THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH THE ANTIBIOTIC STREPTOLYDIGIN | RNA POLYMERASE; STREPTOLYDIGIN; TRANSCRIPTION; HOLOENZYME, TRANSCRIPTION,TRANSFERASE
3auo:A (PRO103) to (ALA154) DNA POLYMERASE X FROM THERMUS THERMOPHILUS HB8 TERNARY COMPLEX WITH 1- NT GAPPED DNA AND DDGTP | RSGI, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, POLXC DOMAIN, PHP DOMAIN, DNA POLYMERASE, DRP LYASE, AP ENDONUCLEASE, 3'-5' EXONUCLEASE, DNA REPAIR, DNA BINDING, NUCLEOTIDE BINDING, TRANSFERASE-DNA COMPLEX
3av0:B (GLN134) to (LEU156) CRYSTAL STRUCTURE OF MRE11-RAD50 BOUND TO ATP S | DNA REPAIR, CALCINEURIN-LIKE PHOSPHOESTERASE, ABC TRANSPORTER ATPASE DOMAIN-LIKE, DNA DOUBLE-STRAND BREAK REPAIR, HERA-NURA COMPLEX, NBS1 IN EUKARYOTES, RECOMBINATION
4q8g:A (SER568) to (PHE648) STRUCTURE OF THE SACCHAROMYCES CEREVISIAE PAN2 PSEUDOUBIQUITIN- HYDROLASE | UBIQUITIN CARBOXYL-TERMINAL HYDROLASE-LIKE DOMAIN, UCH, PAN3, INACTIVE, HYDROLASE
4b21:A (SER55) to (ASN112) UNPRECEDENTED SCULPTING OF DNA AT ABASIC SITES BY DNA GLYCOSYLASE HOMOLOG MAG2 | HYDROLASE-DNA COMPLEX, HELIX-HAIRPIN-HELIX
4b3i:A (PRO548) to (GLY594) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FATTY ACID BETA-OXIDATION COMPLEX WITH COENZYMEA BOUND AT THE HYDRATASE ACTIVE SITES | OXIDOREDUCTASE-TRANSFERASE COMPLEX, TFE, TRIFUNCTIONAL ENZYME, HETERO TETRAMER, COA
4b3j:A (PRO548) to (GLY594) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FATTY ACID BETA-OXIDATION COMPLEX WITH COENZYMEA BOUND AT THE HYDRATASE AND THIOLASE ACTIVE SITES | OXIDOREDUCTASE-TRANSFERASE COMPLEX, TFE, TRIFUNCTIONAL ENZYME, HYDRATASE
2a68:D (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC RIFABUTIN | RNA POLYMERASE HOLOENZYME, RIFABUTIN, ANTIBIOTIC, TRANSCRIPTION REGULATION, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
2a68:N (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC RIFABUTIN | RNA POLYMERASE HOLOENZYME, RIFABUTIN, ANTIBIOTIC, TRANSCRIPTION REGULATION, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
2a69:D (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC RIFAPENTIN | RNA POLYMERASE HOLOENZYME, RIFAPENTIN, ANTIBIOTIC, TRANSCRIPTION REGULATION, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
2a69:N (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC RIFAPENTIN | RNA POLYMERASE HOLOENZYME, RIFAPENTIN, ANTIBIOTIC, TRANSCRIPTION REGULATION, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
3ayn:A (THR293) to (GLU345) CRYSTAL STRUCTURE OF SQUID ISORHODOPSIN | TRANSMEMBRANE PROTEIN, PHOTORECEPTOR, CHROMOPHORE, GLYCOPROTEIN, LIPOPROTEIN, GQ-TYPE G-PROTEIN, PHOSPHORYLATION, MEMBRANE, SIGNALING PROTEIN
2a6e:D (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME | RNA POLYMERASE HOLOENZYME, BRIDGE HELIX, TRANSCRIPTION REGULATION, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
2a6e:N (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME | RNA POLYMERASE HOLOENZYME, BRIDGE HELIX, TRANSCRIPTION REGULATION, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
3m62:A (ASP607) to (ILE655) CRYSTAL STRUCTURE OF UFD2 IN COMPLEX WITH THE UBIQUITIN-LIKE (UBL) DOMAIN OF RAD23 | ARMADILLO-LIKE REPEATS, UBL CONJUGATION PATHWAY, DNA DAMAGE, DNA REPAIR, NUCLEUS, PHOSPHOPROTEIN, LIGASE-PROTEIN BINDING COMPLEX
2a6h:D (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC STERPTOLYDIGIN | RNA POLYMERASE HOLOENZYME, STREPTOLYDIGIN, ANTIBIOTIC, TRANSCRIPTION REGULATION, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
2a6h:N (ALA458) to (ASP504) CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC STERPTOLYDIGIN | RNA POLYMERASE HOLOENZYME, STREPTOLYDIGIN, ANTIBIOTIC, TRANSCRIPTION REGULATION, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
4b7l:A (THR140) to (PRO184) CRYSTAL STRUCTURE OF HUMAN FILAMIN B ACTIN BINDING DOMAIN WITH 1ST FILAMIN REPEAT | STRUCTURAL PROTEIN, FR 1 FILAMIN HINGE ABD-1
4b7l:B (THR140) to (PRO184) CRYSTAL STRUCTURE OF HUMAN FILAMIN B ACTIN BINDING DOMAIN WITH 1ST FILAMIN REPEAT | STRUCTURAL PROTEIN, FR 1 FILAMIN HINGE ABD-1
3b24:B (TYR38) to (GLY73) HSP90 ALPHA N-TERMINAL DOMAIN IN COMPLEX WITH AN AMINOTRIAZINE FRAGMENT MOLECULE | CHAPERONE-CHAPERONE INHIBITOR COMPLEX
3m6z:B (PHE87) to (LEU118) CRYSTAL STRUCTURE OF AN N-TERMINAL 44 KDA FRAGMENT OF TOPOISOMERASE V IN THE PRESENCE OF GUANIDIUM HYDROCHLORIDE | HELIX-HAIRPIN-HELIX, TOPOISOMERASE, CONFORMATIONAL CHANGES IN PROTEIN, ISOMERASE
2a97:A (GLY272) to (LYS323) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF CLOSTRIDIUM BOTULINUM NEUROTOXIN SEROTYPE F | CLOSTRIDIUM BOTULINUM NEUROTOXIN SEROTYPE F; LIGHT CHAIN; CATALYTIC DOMAIN; X-RAY; CRYSTAL STRUCTURE; ZINC ENDOPEPTIDASE, HYDROLASE
2a97:B (GLY272) to (LYS323) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF CLOSTRIDIUM BOTULINUM NEUROTOXIN SEROTYPE F | CLOSTRIDIUM BOTULINUM NEUROTOXIN SEROTYPE F; LIGHT CHAIN; CATALYTIC DOMAIN; X-RAY; CRYSTAL STRUCTURE; ZINC ENDOPEPTIDASE, HYDROLASE
4bbm:A (GLY180) to (LYS231) CRYSTAL STRUCTURE OF THE HUMAN CDKL2 KINASE DOMAIN WITH BOUND TCS 2312 | TRANSFERASE, PHOSPHO-MIMETIC
4bbm:B (GLY180) to (LYS231) CRYSTAL STRUCTURE OF THE HUMAN CDKL2 KINASE DOMAIN WITH BOUND TCS 2312 | TRANSFERASE, PHOSPHO-MIMETIC
3mes:A (GLU327) to (GLY413) CRYSTAL STRUCTURE OF CHOLINE KINASE FROM CRYPTOSPORIDIUM PARVUM IOWA II, CGD3_2030 | CHOLINE KINASE, MALARIA, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, KINASE, TRANSFERASE
3mes:B (GLU327) to (GLY413) CRYSTAL STRUCTURE OF CHOLINE KINASE FROM CRYPTOSPORIDIUM PARVUM IOWA II, CGD3_2030 | CHOLINE KINASE, MALARIA, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, KINASE, TRANSFERASE
3b8z:B (HIS420) to (LEU475) HIGH RESOLUTION CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF ADAMTS-5 (AGGRECANASE-2) | ALPHA/BETA, HYDROLASE
5enn:A (ASP388) to (GLY414) THE CRYSTAL STRUCTURE OF HUMAN VPS34 IN COMPLEX WITH A SELECTIVE AND POTENT INHIBITOR | VPS34, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5enn:B (ASP388) to (GLY414) THE CRYSTAL STRUCTURE OF HUMAN VPS34 IN COMPLEX WITH A SELECTIVE AND POTENT INHIBITOR | VPS34, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3mkn:A (GLY188) to (PHE228) CRYSTAL STRUCTURE OF THE E. COLI PYRIMIDINE NUCLEOSIDASE YEIK BOUND TO A COMPETITIVE INHIBITOR | PYRIMIDINE NUCLEOSIDE HYDROLASE, NUCLEOTIDE METABOLISM, ENZYME- INHIBITOR COMPLEX, METALLOENZYME, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3mkn:C (LEU189) to (THR223) CRYSTAL STRUCTURE OF THE E. COLI PYRIMIDINE NUCLEOSIDASE YEIK BOUND TO A COMPETITIVE INHIBITOR | PYRIMIDINE NUCLEOSIDE HYDROLASE, NUCLEOTIDE METABOLISM, ENZYME- INHIBITOR COMPLEX, METALLOENZYME, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3mkn:D (LEU189) to (GLU229) CRYSTAL STRUCTURE OF THE E. COLI PYRIMIDINE NUCLEOSIDASE YEIK BOUND TO A COMPETITIVE INHIBITOR | PYRIMIDINE NUCLEOSIDE HYDROLASE, NUCLEOTIDE METABOLISM, ENZYME- INHIBITOR COMPLEX, METALLOENZYME, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5eqd:A (GLY114) to (LEU157) STRUCTURE OF OXIDIZED UDP-GALACTOPYRANOSE MUTASE FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH UDP IN OPENED AND CLOSED FORM | GALACTOFURANOSE, ISOMERASE
5eqp:A (THR371) to (LEU455) CRYSTAL STRUCTURE OF CHOLINE KINASE ALPHA-1 BOUND BY 6-[(4-METHYL-1,4- DIAZEPAN-1-YL)METHYL]QUINOLINE (COMPOUND 37) | KINASE, INHIBITOR, COMPLEX, DRUG TARGET, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5eqy:A (THR371) to (LEU455) CRYSTAL STRUCTURE OF CHOLINE KINASE ALPHA-1 BOUND BY 5-[(4-METHYL-1,4- DIAZEPAN-1-YL)METHYL]-2-[4-[(4-METHYL-1,4-DIAZEPAN-1-YL) METHYL]PHENYL]BENZENECARBONITRILE (COMPOUND 65) | KINASE, INHIBITOR, DRUG TARGET, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3bfh:A (ILE45) to (GLN79) CRYSTAL STRUCTURE OF A PHEROMONE BINDING PROTEIN FROM APIS MELLIFERA IN COMPLEX WITH HEXADECANOIC ACID | HONEYBEE, APIS MELLIFERA, PHEROMONE BINDING PROTEIN, SIGNAL TRANSDUCTION, QUEEN MANDIBULAR PHEROMONE, HEXADECANOIC ACID, PHEROMONE-BINDING PROTEIN
5eui:A (ASP6) to (PHE43) STRUCTURE OF PREDICTED ANCESTRAL PIKA HEMOGLOBIN | HEMOGLOBIN, PIKA, OXYGEN-TRANSPORT, RECOMBINANT, OXYGEN TRANSPORT
4quv:A (GLY350) to (LYS406) STRUCTURE OF AN INTEGRAL MEMBRANE DELTA(14)-STEROL REDUCTASE | MEMBRANE PROTEIN, CHOLESTEROL BIOSYNTHESIS, OXIDOREDUCTASE
3br9:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, CYTOPLASM, HOST- VIRUS INTERACTION, ANTIVIRAL, VIRAL NUCLEOPROTEIN, HYDROLASE
3br9:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, CYTOPLASM, HOST- VIRUS INTERACTION, ANTIVIRAL, VIRAL NUCLEOPROTEIN, HYDROLASE
3bsa:B (SER478) to (TYR524) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN
3mwv:A (SER478) to (ARG523) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE | HCV VIRUS RDRP NS5B POLYMERASE, TRANSFERASE
3mwv:B (SER478) to (ARG523) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE | HCV VIRUS RDRP NS5B POLYMERASE, TRANSFERASE
3mww:B (SER478) to (ASN527) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE | HCV VIRUS RDRP NS5B POLYMERASE INHIBITOR, TRANSFERASE
3myd:A (TYR534) to (PRO566) STRUCTURE OF THE CYTOPLASMIC DOMAIN OF FLHA FROM HELICOBACTER PYLORI | FLHA, FLAGELLAR EXPORT, TYPE III SECRETION, CYTOPLASMIC FRAGMENT, PROTEIN TRANSPORT
4br3:B (THR371) to (LEU455) DETERMINATION OF POTENTIAL SCAFFOLDS FOR HUMAN CHOLINE KINASE ALPHA 1 BY CHEMICAL DECONVOLUTION STUDIES | TRANSFERASE
3n1x:A (LEU76) to (GLY98) X-RAY CRYSTAL STRUCTURE OF TOLUENE/O-XYLENE MONOOXYGENASE HYDROXYLASE T201C MUTANT | DIIRON, 4-HELIX BUNDLE, CARBOXYLATE BRIDGE, METALLOENZYME, OXIDOREDUCTASE
3n20:A (LEU76) to (ALA101) X-RAY CRYSTAL STRUCTURE OF TOLUENE/O-XYLENE MONOOXYGENASE HYDROXYLASE T201V MUTANT | DIIRON, 4-HELIX BUNDLE, CARBOXYLATE BRIDGE, METALLOENZYME, OXIDOREDUCTASE
5fau:D (GLY220) to (ARG285) WILD-TYPE CHOLINE TMA LYASE IN COMPLEX WITH CHOLINE | RADICAL, LYASE, BARREL
4bwe:A (CYS32) to (ALA138) CRYSTAL STRUCTURE OF C-TERMINALLY TRUNCATED GLYPICAN-1 AFTER CONTROLLED DEHYDRATION TO 86 PERCENT RELATIVE HUMIDITY | MEMBRANE PROTEIN, PROTEOGLYCAN, GLYCOSAMINOGLYCANS, HEPARAN SULFATE, GLYCOPROTEIN, HELICAL BUNDLE
4bwe:D (CYS32) to (ALA138) CRYSTAL STRUCTURE OF C-TERMINALLY TRUNCATED GLYPICAN-1 AFTER CONTROLLED DEHYDRATION TO 86 PERCENT RELATIVE HUMIDITY | MEMBRANE PROTEIN, PROTEOGLYCAN, GLYCOSAMINOGLYCANS, HEPARAN SULFATE, GLYCOPROTEIN, HELICAL BUNDLE
3c5i:A (SER276) to (ASN363) CRYSTAL STRUCTURE OF PLASMODIUM KNOWLESI CHOLINE KINASE, PKH_134520 | CHOLINE, KINASE, MALARIA, PLASMODIUM KNOWLESI, TRANSFERASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
3c5i:B (SER276) to (ASN363) CRYSTAL STRUCTURE OF PLASMODIUM KNOWLESI CHOLINE KINASE, PKH_134520 | CHOLINE, KINASE, MALARIA, PLASMODIUM KNOWLESI, TRANSFERASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
3c5i:C (SER276) to (ASN363) CRYSTAL STRUCTURE OF PLASMODIUM KNOWLESI CHOLINE KINASE, PKH_134520 | CHOLINE, KINASE, MALARIA, PLASMODIUM KNOWLESI, TRANSFERASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
3c5i:D (SER276) to (ASN363) CRYSTAL STRUCTURE OF PLASMODIUM KNOWLESI CHOLINE KINASE, PKH_134520 | CHOLINE, KINASE, MALARIA, PLASMODIUM KNOWLESI, TRANSFERASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
4c0n:A (ASN26) to (SER60) CRYSTAL STRUCTURE OF NON SYMBIOTIC PLANT HEMOGLOBIN AHB3 (GLB3) FROM ARABIDOPSIS THALIANA | OXYGEN TRANSPORT, 2-OVER-2 FOLD
3cdn:A (ILE45) to (GLN79) CRYSTAL STRUCTURE OF A PHEROMONE BINDING PROTEIN FROM APIS MELLIFERA SOAKED AT PH 4.0 | HONEYBEE, APIS MELLIFERA, PHEROMONE BINDING PROTEIN, SIGNAL TRANSDUCTION, QUEEN MANDIBULAR PHEROMONE, PHEROMONE-BINDING PROTEIN
3ceg:A (PHE4723) to (HIS4772) CRYSTAL STRUCTURE OF THE UBC DOMAIN OF BACULOVIRAL IAP REPEAT- CONTAINING PROTEIN 6 | APOPTOSIS, LIGASE, PROTEASE INHIBITOR, THIOL PROTEASE INHIBITOR, UBL CONJUGATION PATHWAY, STRUCTURAL GENOMICS CONSORTIUM, SGC
3ncz:B (PHE7) to (TYR59) X-RAY CO-STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE (ROCK1) WITH A POTENT 2H-ISOQUINOLIN-1-ONE INHIBITOR | RHO KINASE, DIMER, PHOSPHORYLATION, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
5fl0:A (LYS489) to (GLN543) STRUCTURE OF A HYDROLASE WITH AN INHIBITOR | HYDROLASE
3ndm:C (SER6) to (TYR59) CRYSTAL STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE (ROCK1) WITH A POTENT ISOQUINOLONE DERIVATIVE | RHO KINASE, PHOSPHORYLATION, DIMERIZATION, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4c44:A (ASN26) to (SER60) CRYSTAL STRUCTURE OF TRUNCATED PLANT HEMOGLOBIN FROM ARABIDOPSIS THALIANA | OXYGEN BINDING
3ciz:B (SER478) to (ASN527) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3cj0:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj0:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj3:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj4:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj4:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj5:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3cj5:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
5fmz:B (GLN678) to (ILE749) CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' VRNA | TRANSCRIPTION, INFLUENZA B VIRUS RNA-DEPENDENT RNA POLYMERASE, HETEROTRIMER, VIRAL RNA, VRNA 5' END.
5fnf:A (TYR38) to (GLY73) DYNAMIC UNDOCKING AND THE QUASI-BOUND STATE AS TOOLS FOR DRUG DESIGN | HSP90, DRUG DESIGN, CHAPERONE, ONCOLOGY
4ria:B (LYS539) to (LEU641) FAN1 NUCLEASE BOUND TO 5' PHOSPHORYLATED NICKED DNA | NUCLEASE, HYDROLASE-DNA COMPLEX
4cca:A (GLN328) to (ASP395) STRUCTURE OF HUMAN MUNC18-2 | PROTEIN TRANSPORT
5ft8:A (PRO6) to (TYR65) STRUCTURE OF A CYSTEINE DESULFURASE-SULFUR ACCEPTOR COMPLEX FROM ESCHERICHIA COLI AT 2.50 ANGSTROEM RESOLUTION | TRANSFERASE, L-CYSTEINE DESULFURASE, SULFUR ACCEPTOR, TRANSPERSULFURATION, SULFUR TRAFFICKING
5ft8:E (PRO6) to (TYR65) STRUCTURE OF A CYSTEINE DESULFURASE-SULFUR ACCEPTOR COMPLEX FROM ESCHERICHIA COLI AT 2.50 ANGSTROEM RESOLUTION | TRANSFERASE, L-CYSTEINE DESULFURASE, SULFUR ACCEPTOR, TRANSPERSULFURATION, SULFUR TRAFFICKING
5ft8:K (PRO6) to (ALA67) STRUCTURE OF A CYSTEINE DESULFURASE-SULFUR ACCEPTOR COMPLEX FROM ESCHERICHIA COLI AT 2.50 ANGSTROEM RESOLUTION | TRANSFERASE, L-CYSTEINE DESULFURASE, SULFUR ACCEPTOR, TRANSPERSULFURATION, SULFUR TRAFFICKING
5ft8:M (PRO6) to (TYR65) STRUCTURE OF A CYSTEINE DESULFURASE-SULFUR ACCEPTOR COMPLEX FROM ESCHERICHIA COLI AT 2.50 ANGSTROEM RESOLUTION | TRANSFERASE, L-CYSTEINE DESULFURASE, SULFUR ACCEPTOR, TRANSPERSULFURATION, SULFUR TRAFFICKING
5ft8:O (ALA7) to (TYR65) STRUCTURE OF A CYSTEINE DESULFURASE-SULFUR ACCEPTOR COMPLEX FROM ESCHERICHIA COLI AT 2.50 ANGSTROEM RESOLUTION | TRANSFERASE, L-CYSTEINE DESULFURASE, SULFUR ACCEPTOR, TRANSPERSULFURATION, SULFUR TRAFFICKING
4rph:C (GLY105) to (LEU148) CRYSTAL STRUCTURE OF MICOBACTERIUM TUBERCULOSIS UDP-GALACTOPYRANOSE MUTASE IN COMPLEX WITH SUBSTRATE UDP-GALP (REDUCED) | UDP-GALACTOPYRANOSE MUTASE, MTUGM, FLAVOENZYME, FAD, ISOMERASE
3cqg:B (GLU1010) to (ILE1058) NUCLEOPORIN NUP107/NUP133 INTERACTION COMPLEX, DELTA FINGER MUTANT | NUCLEOPORINS, NUCLEAR PORE COMPLEX, MRNA TRANSPORT, NUCLEUS, PHOSPHOPROTEIN, PROTEIN TRANSPORT, TRANSLOCATION
4cga:A (THR371) to (GLY456) HUMAN CHOLINE KINASE A1 IN COMPLEX WITH COMPOUND 5 | TRANSFERASE, CANCER, DRUG TARGET, BISCATIONIC COMPOUNDS
3cso:A (SER478) to (TYR524) HCV POLYMERASE IN COMPLEX WITH A 1,5 BENZODIAZEPINE INHIBITOR | 1,5-BENZODIAZEPINES, HEPATITIS C VIRUS, NS5B, POLYMERASE, TRANSFERASE
3cso:B (SER478) to (TYR524) HCV POLYMERASE IN COMPLEX WITH A 1,5 BENZODIAZEPINE INHIBITOR | 1,5-BENZODIAZEPINES, HEPATITIS C VIRUS, NS5B, POLYMERASE, TRANSFERASE
3cwj:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, HEPATITIS, TRANSFERASE, VIRAL PROTEIN
3cwj:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, HEPATITIS, TRANSFERASE, VIRAL PROTEIN
3o2u:A (ASP1128) to (GLY1174) S. CEREVISIAE UBC12 | E2 CONJUGASE, LIGASE
3cx7:A (ASP77) to (PHE125) CRYSTAL STRUCTURE OF PDZRHOGEF RGRGS DOMAIN IN A COMPLEX WITH GALPHA-13 BOUND TO GDP-ALF4 | SIGNAL TRANSDUCTION, PROTEIN COMPLEX, SIGNALING PROTEIN
3cx8:A (ASP77) to (PHE125) CRYSTAL STRUCTURE OF PDZRHOGEF RGRGS DOMAIN IN A COMPLEX WITH GALPHA-13 BOUND TO GTP-GAMMA-S | SIGNAL TRANSDUCTION, PROTEIN COMPLEX, GTP-BINDING, LIPOPROTEIN, MEMBRANE, NUCLEOTIDE-BINDING, PALMITATE, PHOSPHOPROTEIN, TRANSDUCER, COILED COIL, CYTOPLASM, GTPASE ACTIVATION, GUANINE-NUCLEOTIDE RELEASING FACTOR, SIGNALING PROTEIN
4ry4:A (SER478) to (PHE526) C-TERMINAL MUTANT (Y448F) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4ry4:B (SER478) to (TYR524) C-TERMINAL MUTANT (Y448F) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4ry3:A (LYS539) to (HIS644) CRYSTAL STRUCTURE OF HUMAN FANCONI-ASSOCIATED NUCLEASE 1 | ENDONUCLEASE 5'-3'EXONULEASE, FANCD2, FAN1, HYDROLASE
4ry3:A (LEU719) to (VAL751) CRYSTAL STRUCTURE OF HUMAN FANCONI-ASSOCIATED NUCLEASE 1 | ENDONUCLEASE 5'-3'EXONULEASE, FANCD2, FAN1, HYDROLASE
4ry5:A (SER478) to (ARG523) C-TERMINAL MUTANT (W550N) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4ry7:A (PRO479) to (ALA529) C-TERMINAL MUTANT (D559E) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4ry7:B (SER478) to (ARG523) C-TERMINAL MUTANT (D559E) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
3o4x:E (HIS1026) to (TYR1104) CRYSTAL STRUCTURE OF COMPLEX BETWEEN AMINO AND CARBOXY TERMINAL FRAGMENTS OF MDIA1 | AUTOINHIBITION, ACTIN NUCLEATOR, ACTIN BINDING, PROTEIN BINDING
3o4x:H (HIS1026) to (ASP1103) CRYSTAL STRUCTURE OF COMPLEX BETWEEN AMINO AND CARBOXY TERMINAL FRAGMENTS OF MDIA1 | AUTOINHIBITION, ACTIN NUCLEATOR, ACTIN BINDING, PROTEIN BINDING
3o4x:G (VAL1027) to (VAL1106) CRYSTAL STRUCTURE OF COMPLEX BETWEEN AMINO AND CARBOXY TERMINAL FRAGMENTS OF MDIA1 | AUTOINHIBITION, ACTIN NUCLEATOR, ACTIN BINDING, PROTEIN BINDING
3o4x:F (HIS1026) to (TYR1104) CRYSTAL STRUCTURE OF COMPLEX BETWEEN AMINO AND CARBOXY TERMINAL FRAGMENTS OF MDIA1 | AUTOINHIBITION, ACTIN NUCLEATOR, ACTIN BINDING, PROTEIN BINDING
4co6:B (GLY305) to (PRO328) CRYSTAL STRUCTURE OF THE NIPAH VIRUS RNA FREE NUCLEOPROTEIN-PHOSPHOPROTEIN COMPLEX | CHAPERONE, VIRAL PROTEIN, VIRAL REPLICATION, PARAMYXOVIRUS
3d3x:B (GLY256) to (TYR306) CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE E CATALYTIC DOMAIN IN COMPLEX WITH SNAP-25 SUBSTRATE PEPTIDE | BONT E, SNAP-25, ENZYME-SUBSTRATE COMPLEX, HYDROLASE, HYDROLASE- HYDROLASE SUBSTRATE COMPLEX
3d77:A (ILE45) to (GLN79) CRYSTAL STRUCTURE OF A PHEROMONE BINDING PROTEIN MUTANT D35N, FROM APIS MELLIFERA, SOAKED AT PH 4.0 | PHEROMONE BINDING PROTEIN, HONEY BEE, APIS MELLIFERA, SIGNAL TRANSDUCTION, QUEEN MANDIBULAR PROTEIN, PH
3obv:E (HIS1026) to (TYR1104) AUTOINHIBITED FORMIN MDIA1 STRUCTURE | AUTOINHIBITION, ACTIN, NUCLEATION, CYTOSKELETON, STRUCTURAL PROTEIN
3obv:F (HIS1026) to (VAL1106) AUTOINHIBITED FORMIN MDIA1 STRUCTURE | AUTOINHIBITION, ACTIN, NUCLEATION, CYTOSKELETON, STRUCTURAL PROTEIN
3obv:G (HIS1026) to (TYR1104) AUTOINHIBITED FORMIN MDIA1 STRUCTURE | AUTOINHIBITION, ACTIN, NUCLEATION, CYTOSKELETON, STRUCTURAL PROTEIN
3obv:H (HIS1026) to (VAL1106) AUTOINHIBITED FORMIN MDIA1 STRUCTURE | AUTOINHIBITION, ACTIN, NUCLEATION, CYTOSKELETON, STRUCTURAL PROTEIN
3da4:A (GLN39) to (HIS93) CRYSTAL STRUCTURE OF COLICIN M, A NOVEL PHOSPHATASE SPECIFICALLY IMPORTED BY ESCHERICHIA COLI | COLICIN M, PHOSPHATASE, CRYSTAL STRUCTURE, ANTIBIOTIC, ANTIMICROBIAL, BACTERIOCIN, PLASMID, TONB BOX
3odm:D (GLN423) to (ASN476) ARCHAEAL-TYPE PHOSPHOENOLPYRUVATE CARBOXYLASE | BETA-BARREL, LYASE
3odm:G (GLU424) to (GLU473) ARCHAEAL-TYPE PHOSPHOENOLPYRUVATE CARBOXYLASE | BETA-BARREL, LYASE
3dc6:C (LEU14) to (ASN80) CRYSTAL STRUCTURE OF A MANGANESE SUPEROXIDE DISMUTASES FROM CAENORHABDITIS ELEGANS | ALPHA HAIRPIN N DOMAIN, ALPHA/BETA C DOMAIN, OXIDOREDUCTASE, MANGANESE, METAL-BINDING, MITOCHONDRION, TRANSIT PEPTIDE
4cwu:U (PHE47) to (GLU115) CRYSTAL STRUCTURE DERIVED MODELS OF ADENOVIRUS CEMENT PROTEINS AT 3.8A | VIRUS, ADENOVIRUS, CEMENT PROTEINS, PROTEIN VI
4tpw:B (ASN118) to (ASP148) THE CO-COMPLEX STRUCTURE OF THE TRANSLATION INITIATION FACTOR EIF4E WITH THE INHIBITOR 4EGI-1 REVEALS AN ALLOSTERIC MECHANISM FOR DISSOCIATING EIF4G | EIF4E, 4EGI1, ALLOSTERIC, TRANSLATION INITIATION INHIBITOR, PROTEIN BINDING
4tqb:B (ASN118) to (ASP148) THE CO-COMPLEX STRUCTURE OF THE TRANSLATION INITIATION FACTOR EIF4E WITH THE INHIBITOR 4EGI-1 REVEALS AN ALLOSTERIC MECHANISM FOR DISSOCIATING EIF4G | EIF4E, TRANSLATION INITIATION INHIBITOR, ALLOSTERIC, 4EGI1, PROTEIN BINDING
5gh0:A (PRO197) to (LEU283) CRYSTAL STRUCTURE OF THE COMPLEX OF BOVINE LACTOPEROXIDASE WITH MERCAPTOIMIDAZOLE AT 2.3 A RESOLUTION | OXIDOREDUCTASE
4d10:F (GLU194) to (CYS266) CRYSTAL STRUCTURE OF THE COP9 SIGNALOSOME | SIGNALING PROTEIN
4d10:N (GLU194) to (CYS266) CRYSTAL STRUCTURE OF THE COP9 SIGNALOSOME | SIGNALING PROTEIN
4d18:F (GLU194) to (CYS266) CRYSTAL STRUCTURE OF THE COP9 SIGNALOSOME | SIGNALING PROTEIN, PCI COMPLEX, CSN, SGN, MPN DOMAIN,
4d18:N (GLU194) to (CYS266) CRYSTAL STRUCTURE OF THE COP9 SIGNALOSOME | SIGNALING PROTEIN, PCI COMPLEX, CSN, SGN, MPN DOMAIN,
4txs:A (SER478) to (PHE526) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, TETRAMER, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4txs:B (SER478) to (TYR524) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, TETRAMER, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4txs:C (SER478) to (PHE526) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, TETRAMER, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4txs:D (SER478) to (TYR524) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, TETRAMER, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ty8:A (SER478) to (TYR524) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ty8:B (SER478) to (PHE526) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ty8:D (SER478) to (LYS523) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ty9:A (SER478) to (PHE526) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANAFERASE-TRANSFERASE INHIBITOR COMPLEX
4ty9:B (SER478) to (TYR524) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANAFERASE-TRANSFERASE INHIBITOR COMPLEX
4ty9:C (SER478) to (TYR524) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANAFERASE-TRANSFERASE INHIBITOR COMPLEX
4ty9:D (SER478) to (LYS523) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | NS5B, TRANAFERASE-TRANSFERASE INHIBITOR COMPLEX
4tya:B (SER478) to (LYS523) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4tya:D (SER478) to (LYS523) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4tyb:B (SER478) to (TYR524) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4tyb:D (SER478) to (PHE526) AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE | INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4d9g:A (SER315) to (LEU363) CRYSTAL STRUCTURE OF SELENOMETHIONINE INCORPORATED HOLO DIAMINOPROPIONATE AMMONIA LYASE FROM ESCHERICHIA COLI | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE, S-HYDROXYETHYLATION OF CYSTEINE
4d9g:B (SER315) to (ALA364) CRYSTAL STRUCTURE OF SELENOMETHIONINE INCORPORATED HOLO DIAMINOPROPIONATE AMMONIA LYASE FROM ESCHERICHIA COLI | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE, S-HYDROXYETHYLATION OF CYSTEINE
4d9i:B (SER315) to (ALA364) CRYSTAL STRUCTURE OF HOLO DIAMINOPROPIONATE AMMONIA LYASE FROM ESCHERICHIA COLI | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4d9k:D (SER315) to (LEU363) CRYSTAL STRUCTURE OF ESCHERICHIA COLI DIAMINOPROPIONATE AMMONIA LYASE IN APO FORM | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE, S-HYDROXYETHYLATION OF CYSTEINE
4d9k:C (SER315) to (LEU363) CRYSTAL STRUCTURE OF ESCHERICHIA COLI DIAMINOPROPIONATE AMMONIA LYASE IN APO FORM | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE, S-HYDROXYETHYLATION OF CYSTEINE
4d9m:B (SER315) to (ALA364) CRYSTAL STRUCTURE OF DIAMINOPROPIONATE AMMONIA LYASE FROM ESCHERICHIA COLI IN COMPLEX WITH AMINOACRYLATE-PLP AZOMETHINE REACTION INTERMEDIATE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
5ham:A (ASP624) to (ARG680) STRUCTURE OF RICKETTSIA BELLII EFFECTOR PROTEIN RICKCE | ENZYME, CE CLAN, DEUBIQUITINASE, HYDROLASE
4da5:B (THR371) to (LEU455) CHOLINE KINASE ALPHA ACTS THROUGH A DOUBLE-DISPLACEMENT KINETIC MECHANISM INVOLVING ENZYME ISOMERISATION, AS DETERMINED THROUGH ENZYME AND INHIBITOR KINETICS AND STRUCTURAL BIOLOGY | KINASE, SIGNAL TRANSDUCTION, CYTOPLASMIC, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5hb4:B (ASN977) to (THR1032) CRYSTAL STRUCTURE OF CHAETOMIUM THERMOPHILUM NUP192 | NUCLEOCYTOPLASMIC TRANSPORT, PROTEIN TRANSPORT, TRANSPORT PROTEIN
5hdt:B (SER249) to (LEU270) HUMAN COHESIN REGULATOR PDS5B BOUND TO A WAPL PEPTIDE | COHESIN REGULATOR, PDS5B, WAPL, IP6, CELL CYCLE
3p0b:A (THR60) to (SER121) THERMUS THERMOPHILUS FAMILY GH57 BRANCHING ENZYME: CRYSTAL STRUCTURE, MECHANISM OF ACTION AND PRODUCTS FORMED | GLYCOSIDE HYDROLASE GH57, GLYCOGEN BRANCHING, TRANSFERASE
4djh:A (LEU1039) to (LEU1091) STRUCTURE OF THE HUMAN KAPPA OPIOID RECEPTOR IN COMPLEX WITH JDTIC | JDTIC, GPCR NEWTORK, PSI-BIOLOGY, KOR, HKOR, KOP, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, GPCR NETWORK, G-PROTEIN COUPLED RECEPTOR, GPCR, 7TM, KAPPA OPIOID RECEPTOR, DYNORPHIN, MEMBRANE PROTEIN, TRANSMEMBRANE, HORMONE RECEPTOR, HYDROLASE, HORMONE RECEPTOR-ANTAGONIST COMPLEX
4u6u:B (THR304) to (SER351) CRYSTAL STRUCTURE OF THE COG5-COG7 COMPLEX FROM KLUYVEROMYCES LACTIS | MULTISUBUNIT TETHERING COMPLEX, CONSERVED OLIGOMERIC GOLGI COMPLEX, COILED COIL, VESICLE FUSION, TRANSPORT PROTEIN
4u6u:D (LEU305) to (SER351) CRYSTAL STRUCTURE OF THE COG5-COG7 COMPLEX FROM KLUYVEROMYCES LACTIS | MULTISUBUNIT TETHERING COMPLEX, CONSERVED OLIGOMERIC GOLGI COMPLEX, COILED COIL, VESICLE FUSION, TRANSPORT PROTEIN
4dru:A (SER478) to (PHE526) HCV NS5B IN COMPLEX WITH MACROCYCLIC INDOLE INHIBITOR | HCV POLYMERASE, MACROCYCLE INHIBITOR, THUMB DOMAIN, TRANSFERASE- INHIBITOR COMPLEX
4dru:B (SER478) to (ARG523) HCV NS5B IN COMPLEX WITH MACROCYCLIC INDOLE INHIBITOR | HCV POLYMERASE, MACROCYCLE INHIBITOR, THUMB DOMAIN, TRANSFERASE- INHIBITOR COMPLEX
3e51:A (SER478) to (ASN527) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEOTIDE-BINDING, TRANSCRIPTION, TRANSFERASE
3ph7:C (LEU339) to (LEU392) CRYSTAL STRUCTURE OF PLASMODIUM VIVAX PUTATIVE POLYPRENYL PYROPHOSPHATE SYNTHASE IN COMPLEX WITH GERANYLGERANYL DIPHOSPHATE | MALARIA, FARNESYL PYROPHOSPHATE SYNTHASE DIPHOSPHATE, LYASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
4ur9:B (LYS489) to (SER545) STRUCTURE OF LIGAND BOUND GLYCOSYLHYDROLASE | HYDROLASE
4eah:A (PHE832) to (GLY903) CRYSTAL STRUCTURE OF THE FORMIN HOMOLOGY 2 DOMAIN OF FMNL3 BOUND TO ACTIN | ATP BINDING, CYTOSKELETON, FORMIN, FMNL3, ACTIN, PROTEIN BINDING
4eah:E (PHE832) to (GLY903) CRYSTAL STRUCTURE OF THE FORMIN HOMOLOGY 2 DOMAIN OF FMNL3 BOUND TO ACTIN | ATP BINDING, CYTOSKELETON, FORMIN, FMNL3, ACTIN, PROTEIN BINDING
4eah:C (PHE832) to (GLY903) CRYSTAL STRUCTURE OF THE FORMIN HOMOLOGY 2 DOMAIN OF FMNL3 BOUND TO ACTIN | ATP BINDING, CYTOSKELETON, FORMIN, FMNL3, ACTIN, PROTEIN BINDING
4eah:B (PHE832) to (GLY903) CRYSTAL STRUCTURE OF THE FORMIN HOMOLOGY 2 DOMAIN OF FMNL3 BOUND TO ACTIN | ATP BINDING, CYTOSKELETON, FORMIN, FMNL3, ACTIN, PROTEIN BINDING
4eaw:A (SER478) to (ARG523) HCV NS5B IN COMPLEX WITH IDX375 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4eaw:B (SER478) to (ARG523) HCV NS5B IN COMPLEX WITH IDX375 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3puk:B (GLN329) to (ASN396) RE-REFINEMENT OF THE CRYSTAL STRUCTURE OF MUNC18-3 AND SYNTAXIN4 N- PEPTIDE COMPLEX | MEMBRANE TRAFFICKING, SM PROTEIN, SYNTAXIN, SNARE PROTEINS, SYNTAXIN BINDING PROTEIN, ENDOCYTOSIS-EXOCYTOSIS COMPLEX
4egh:A (TYR38) to (GLY73) HSP90-ALPHA ATPASE DOMAIN IN COMPLEX WITH (4-HYDROXYPHENYL)MORPHOLIN- 4-YL METHANONE | BERGERAT FOLD, HYDROLASE, ATP BINDING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3pyb:B (PRO250) to (GLN299) CRYSTAL STRUCTURE OF ENT-COPALYL DIPHOSPHATE SYNTHASE FROM ARABIDOPSIS THALIANA IN COMPLEX WITH 13-AZA-13,14-DIHYDROCOPALYL DIPHOSPHATE | CLASS I AND II TERPENE CYCLASE FOLD, CLASS II DITERPENE CYCLASE, DXXDD MOTIF, GIBBERELLIN BIOSYNTHESIS, BIOSYNTHESIS OF ENT-COPALYL DIPHOSPHATE, ISOMERASE
3q0l:B (SER830) to (ILE885) CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH P38ALPHA NREA | PUF, PUMILIO-HOMOLGY DOMAIN, GENE REGULATION, RNA BINDING, RNA BINDING PROTEIN-RNA COMPLEX
3q0p:A (SER830) to (ILE885) CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH HUNCHBACK NRE | PUF, PUMILIO-HOMOLGY DOMAIN, GENE REGULATION, RNA BINDING, RNA BINDING PROTEIN-RNA COMPLEX
3q0z:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3q0z:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3q2k:H (ILE286) to (ARG340) CRYSTAL STRUCTURE OF THE WLBA DEHYDROGENASE FROM BORDETELLA PERTUSSIS IN COMPLEX WITH NADH AND UDP-GLCNACA | ROSSMANN FOLD, DEHYDROGENASE, NAD, UDP-SUGAR, OXIDOREDUCTASE
5ir6:A (ASP170) to (GLU247) THE STRUCTURE OF BD OXIDASE FROM GEOBACILLUS THERMODENITRIFICANS | BD OXIDASE, TERMINAL OXIDASE, OXIDOREDUCTASE
5ivw:W (HIS304) to (SER408) HUMAN CORE TFIIH BOUND TO DNA WITHIN THE PIC | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION-DNA COMPLEX
5iy8:W (HIS304) to (SER408) HUMAN HOLO-PIC IN THE INITIAL TRANSCRIBING STATE | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA COMPLEX
5iy9:W (HIS304) to (SER408) HUMAN HOLO-PIC IN THE INITIAL TRANSCRIBING STATE (NO IIS) | INITIATION, RNA POLYMERASE II, HUMAN, TRANSCRIPTION, TRANSFERASE-DNA- RNA COMPLEX
3qgd:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-1-[(4-ETHYLPHENYL)SULFONYL]- N-(4-METHOXYBENZYL)PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qgd:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-1-[(4-ETHYLPHENYL)SULFONYL]- N-(4-METHOXYBENZYL)PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qge:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qge:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qgf:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(6-CHLOROPYRIDAZIN-3-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qgf:B (SER478) to (PHE526) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(6-CHLOROPYRIDAZIN-3-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qgh:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 1A COMPLEX WITH N-CYCLOPROPYL-6-[(3R)-3-{[4- (TRIFLUOROMETHOXY)BENZYL]CARBAMOYL}-4-{[4-(TRIFLUOROMETHOXY) PHENYL]SULFONYL}PIPERAZIN-1-YL]PYRIDAZINE-3-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qgi:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 1A COMPLEX WITH N-[(2S)-BUTAN-2-YL]-6-[(3R)-3- {[4-(TRIFLUOROMETHOXY)BENZYL]CARBAMOYL}-4-{[4-(TRIFLUOROMETHOXY) PHENYL]SULFONYL}PIPERAZIN-1-YL]PYRIDAZINE-3-CARBOXAMIDE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4f5x:W (TYR193) to (TYR234) LOCATION OF THE DSRNA-DEPENDENT POLYMERASE, VP1, IN ROTAVIRUS PARTICLES | BETA-JELLYROLL, POLYMERASE, TRANSCRIPTASE, VIRUS
3qjt:A (PRO16) to (LEU58) THE STRUCTURE OF AND PHOTOLYTIC INDUCED CHANGES OF CARBON MONOXIDE BINDING TO THE CYTOCHROME BA3-OXIDASE FROM THERMUS THERMOPHILUS | CYTOCHROME BA3 OXIDASE, CARBON MONOXIDE, CO PHOTODISSOCIATION, OXIDOREDUCTASE
3qjq:A (PRO16) to (LEU59) THE STRUCTURE OF AND PHOTOLYTIC INDUCED CHANGES OF CARBON MONOXIDE BINDING TO THE CYTOCHROME BA3-OXIDASE FROM THERMUS THERMOPHILUS | CYTOCHROME BA3 OXIDASE, CARBON MONOXIDE, CO PHOTODISSOCIATION, OXIDOREDUCTASE
3qju:A (GLU17) to (LEU59) THE STRUCTURE OF AND PHOTOLYTIC INDUCED CHANGES OF CARBON MONOXIDE BINDING TO THE CYTOCHROME BA3-OXIDASE FROM THERMUS THERMOPHILUS | CYTOCHROME BA3 OXIDASE, CARBON MONOXIDE, CO PHOTODISSOCIATION, OXIDOREDUCTASE
3qku:B (GLN140) to (LEU161) MRE11 RAD50 BINDING DOMAIN IN COMPLEX WITH RAD50 AND AMP-PNP | RECA-LIKE FOLD, COILED-COILS, ATPASE, EXONUCLEASE, ENDONUCLEASE, ATP BINDING, DNA BINDING, REPLICATION
3qmu:J (SER393) to (ALA443) BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH EPICATECHIN-3-GALLATE (ECG) | ROSSMANN FOLD, DEHYDROGENASE, MITOCHONDRIA, OXIDOREDUCTASE
4uwh:A (ASP388) to (GLY414) DISCOVERY OF (2S)-8-((3R)-3-METHYLMORPHOLIN-4-YL)-1-(3- METHYL-2-OXO-BUTYL)-2-(TRIFLUOROMETHYL)-3,4-DIHYDRO-2H- PYRIMIDO(1,2-A)PYRIMIDIN-6-ONE: A NOVEL POTENT AND SELECTIVE INHIBITOR OF VPS34 FOR THE TREATMENT OF SOLID TUMORS | TRANSFERASE, LIPID KINASE, AUTOPHAGY INHIBITOR
4ux3:A (LYS158) to (GLY990) COHESIN SMC3-HD:SCC1-N COMPLEX FROM YEAST | PROTEIN BINDING, COHESIN, MITOSIS, CHROMOSOME SEGREGATION, KLEISIN, SMC
3qnb:A (GLU129) to (VAL193) CRYSTAL STRUCTURE OF AN ENGINEERED OXA-10 VARIANT WITH CARBAPENEMASE ACTIVITY, OXA-10LOOP24 | ANTIBIOTIC RESISTANCE, HYDROLYSIS OF AMIDE BOND OF BETA-LACTAM COMPOUNDS, HYDROLASE
3qnb:B (GLU129) to (VAL193) CRYSTAL STRUCTURE OF AN ENGINEERED OXA-10 VARIANT WITH CARBAPENEMASE ACTIVITY, OXA-10LOOP24 | ANTIBIOTIC RESISTANCE, HYDROLYSIS OF AMIDE BOND OF BETA-LACTAM COMPOUNDS, HYDROLASE
3qnc:A (GLU129) to (VAL193) CRYSTAL STRUCTURE OF A RATIONALLY DESIGNED OXA-10 VARIANT SHOWING CARBAPENEMASE ACTIVITY, OXA-10LOOP48 | ANTIBIOTIC RESISTANCE, HYDROLYSIS OF AMIDE BOND OF BETA-LACTAM COMPOUNDS, HYDROLASE
3qnc:B (GLU129) to (VAL193) CRYSTAL STRUCTURE OF A RATIONALLY DESIGNED OXA-10 VARIANT SHOWING CARBAPENEMASE ACTIVITY, OXA-10LOOP48 | ANTIBIOTIC RESISTANCE, HYDROLYSIS OF AMIDE BOND OF BETA-LACTAM COMPOUNDS, HYDROLASE
4fcp:B (TYR38) to (GLY73) TARGETTING CONSERVED WATER MOLECULES: DESIGN OF 4-ARYL-5-CYANOPYRROLO [2,3-D] PYRIMIDINE HSP90 INHIBITORS USING FRAGMENT-BASED SCREENING AND STRUCTURE-BASED OPTIMIZATION | HSP90, HEAT SHOCK PROTEIN, ATPASE, STRUCTURE-BASED LIGAND DESIGN, FRAGMENT STRUCTURAL STUDIES, CHAPERONE
3qtm:A (LEU130) to (ASN189) CRYSTAL STRUCTURE OF NRO1/ETT1 PROTEIN FROM S. POMBE (HIGH RESOLUTION) | TETRATRICOPEPTIDE REPEAT, ENHANCER OF TRANSLATION TERMINATION, TRANSLATION
3qtn:B (PHE131) to (ASN189) CRYSTAL STRUCTURE OF NRO1/ETT1 PROTEIN FROM S. POMBE (LOW RESOLUTION) | TETRATRICOPEPTIDE REPEAT, ENHANCER OF TRANSLATION TERMINATION, TRANSLATION
4v3k:A (THR98) to (LYS144) RNF38-UBCH5B-UB COMPLEX | RING E3, E2, UBIQUITIN, LIGASE
4v3k:D (THR98) to (MET147) RNF38-UBCH5B-UB COMPLEX | RING E3, E2, UBIQUITIN, LIGASE
4w7p:A (GLU8) to (TYR59) CRYSTAL STRUCTURE OF ROCK 1 BOUND TO YB-15-QD37 | INHIBITOR, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4w7p:B (THR9) to (TYR59) CRYSTAL STRUCTURE OF ROCK 1 BOUND TO YB-15-QD37 | INHIBITOR, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4w7p:C (PHE7) to (TYR59) CRYSTAL STRUCTURE OF ROCK 1 BOUND TO YB-15-QD37 | INHIBITOR, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4w7p:D (THR9) to (TYR59) CRYSTAL STRUCTURE OF ROCK 1 BOUND TO YB-15-QD37 | INHIBITOR, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5jfz:C (GLY140) to (VAL193) E. COLI ECFICT IN COMPLEX WITH ECFICA MUTANT E28G | FIC DOMAIN, FIC-1, CLASS I FIC PROTEIN, TRANSFERASE
4fpa:A (GLY299) to (GLY360) CRYSTAL STRUCTURE OF RECOMBINANT HUMAN HEXOKINASE TYPE I MUTANT D413N GLUCOSE 6-PHOSPHATE | HEXOKINASE, GLUCOSE-6-PHOSPHATE, TRANSFERASE
5jlj:C (PRO922) to (ASN969) CRYSTAL STRUCTURE OF KPT8602 IN COMPLEX WITH CRM1-RAN-RANBP1 | HEAT REPEAT, EXPORTIN-1, NUCLEAR TRANSPORT, TRANSPORT RECEPTOR- INHIBITOR COMPLEX, PROTEIN TRANSPORT
5jk9:C (TRP21) to (HIS50) CRYSTAL STRUCTURE OF HUMAN IZUMO1 | FERTILIZATION, IZUMO1, JUNO, CELL ADHESION
5jkd:A (TRP21) to (HIS50) CRYSTAL STRUCTURE OF HUMAN IZUMO1-JUNO COMPLEX (CRYSTAL FORM 2) | FERTILIZATION, IZUMO1, JUNO, CELL ADHESION
4fxf:A (TYR370) to (LYS422) STRUCTURE OF M2 PYRUVATE KINASE IN COMPLEX WITH PHENYLALANINE | TIM BARREL, TRANSFERASE, ATP BINDING
4fxf:B (TYR370) to (LYS422) STRUCTURE OF M2 PYRUVATE KINASE IN COMPLEX WITH PHENYLALANINE | TIM BARREL, TRANSFERASE, ATP BINDING
5js8:A (SER62) to (GLY117) STRUCTURAL MODEL OF A PROTEIN ALPHA SUBUNIT IN COMPLEX WITH GDP OBTAINED WITH SAXS AND NMR RESIDUAL COUPLINGS | G-PROTEINS, SAXS, SINGLING, GPCR, SIGNALING PROTEIN
5juy:A (GLU447) to (LYS495) ACTIVE HUMAN APOPTOSOME WITH PROCASPASE-9 | APAF-1, APOPTOSIS, PROGRAMMED CELL DEATH, AAA+ ATPASE
5juy:B (GLU447) to (LYS495) ACTIVE HUMAN APOPTOSOME WITH PROCASPASE-9 | APAF-1, APOPTOSIS, PROGRAMMED CELL DEATH, AAA+ ATPASE
5juy:C (GLU447) to (LYS495) ACTIVE HUMAN APOPTOSOME WITH PROCASPASE-9 | APAF-1, APOPTOSIS, PROGRAMMED CELL DEATH, AAA+ ATPASE
5juy:D (GLU447) to (LYS495) ACTIVE HUMAN APOPTOSOME WITH PROCASPASE-9 | APAF-1, APOPTOSIS, PROGRAMMED CELL DEATH, AAA+ ATPASE
5juy:E (GLU447) to (LYS495) ACTIVE HUMAN APOPTOSOME WITH PROCASPASE-9 | APAF-1, APOPTOSIS, PROGRAMMED CELL DEATH, AAA+ ATPASE
5juy:F (GLU447) to (LYS495) ACTIVE HUMAN APOPTOSOME WITH PROCASPASE-9 | APAF-1, APOPTOSIS, PROGRAMMED CELL DEATH, AAA+ ATPASE
5juy:G (GLU447) to (LYS495) ACTIVE HUMAN APOPTOSOME WITH PROCASPASE-9 | APAF-1, APOPTOSIS, PROGRAMMED CELL DEATH, AAA+ ATPASE
4g2u:B (GLU99) to (ALA138) CRYSTAL STRUCTURE ANALYSIS OF OSTERTAGIA OSTERTAGI ASP-1 | CAP PROTEIN, SCP/TAPS PROTEIN, CRISP, ACTIVATION-ASSOCIATED SECRETED PROTEIN, IMMUNE SYSTEM
4g7s:A (GLU17) to (LEU58) STRUCTURE OF RECOMBINANT CYTOCHROME BA3 OXIDASE MUTANT V236I FROM THERMUS THERMOPHILUS | OXIDOREDUCTASE, PROTON PUMP
4g7z:D (GLU459) to (SER505) CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS TRANSCRIPTION INITIATION COMPLEX CONTAINING 5-BRU AT TEMPLATE-STRAND POSITION +1 | PROTEIN-DNA COMPLEX, TRANSCRIPTION INITIATION COMPLEX, RNAP-PROMOTER COMPLEX, RNAP-PROMOTER OPEN COMPLEX, OPEN COMPLEX, RPO, RNA POLYMERASE, TRANSCRIPTION INITIATION, TRANSCRIPTION INITIATION FACTOR SIGMA A, PROMOTER DNA, NUCLEOID, TRANSCRIPTION, TRANSFERASE- DNA COMPLEX
5kaf:B (ASP49) to (ARG68) RT XFEL STRUCTURE OF PHOTOSYSTEM II IN THE DARK STATE AT 3.0 A RESOLUTION | PHOTOSYSTEMS, TRANSMEMBRANE, ROOM TEMPERATURE, ELECTRON TRANSPORT
4gou:A (TYR273) to (THR316) CRYSTAL STRUCTURE OF AN RGS-RHOGEF FROM ENTAMOEBA HISTOLYTICA | RGS DOMAIN, DH DOMAIN, PH DOMAIN, RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR, SIGNALING PROTEIN, GTPASE ACCELERATING PROTEIN, PHOSPHOLIPID BINDING, HETEROTRIMERIC G PROTEIN EFFECTOR, EHGALPHA1
4gp8:A (PRO16) to (PRO60) STRUCTURE OF RECOMBINANT CYTOCHROME BA3 OXIDASE MUTANT Y133W+T231F FROM THERMUS THERMOPHILUS | OXIDOREDUCTASE, PROTON PUMP
5kz5:O (PRO71) to (GLY115) ARCHITECTURE OF THE HUMAN MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY MACHINERY: THE COMPLEX FORMED BY THE IRON DONOR, THE SULFUR DONOR, AND THE SCAFFOLD | FRATAXIN, IRON-SULFUR PROTEIN, MITOCHONDRIA, PROTEIN COMPLEX, TRANSFERASE-OXIDOREDUCTASE COMPLEX
5lm1:A (ILE125) to (ALA179) CRYSTAL STRUCTURE OF HD-PTP PHOSPHATASE IN COMPLEX WITH UBAP1 | COILED COIL, HYDROLASE
5lqx:H (PRO93) to (VAL138) STRUCTURE OF F-ATPASE FROM PICHIA ANGUSTA, STATE3 | ATP SYNTHASE, HYDROLASE
5sv9:A (ILE24) to (ASP74) STRUCTURE OF THE SLC4 TRANSPORTER BOR1P IN AN INWARD-FACING CONFORMATION | BORON TRANSPORTER, ANION EXCHANGER FAMILY, ALTERNATING ACCESS MECHANISM, STRUCTURAL GENOMICS, PSI-BIOLOGY, TRANSCONTINENTAL EM INITIATIVE FOR MEMBRANE PROTEIN STRUCTURE, TEMIMPS, TRANSPORT PROTEIN
5tis:b (ASP49) to (ARG68) ROOM TEMPERATURE XFEL STRUCTURE OF THE NATIVE, DOUBLY-ILLUMINATED PHOTOSYSTEM II COMPLEX | PHOTOSYSTEMS, TRANSMEMBRANE, ROOM TEMPERATURE, ELECTRON TRANSPORT, PHOTOSYNTHESIS
5trh:A (SER478) to (PHE526) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-[(BENZENECARBONYL)AMINO]-3-[(4- CHLOROPHENYL)METHOXY]BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trh:B (SER478) to (PHE526) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-[(BENZENECARBONYL)AMINO]-3-[(4- CHLOROPHENYL)METHOXY]BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trk:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA- DEPENDENT RNA POLYMERASE IN COMPLEX WITH N-{3-[(BENZENECARBONYL)AMINO]-4-[(4- CHLOROPHENYL)METHOXY]BENZENE-1-CARBONYL}GLYCINE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trk:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA- DEPENDENT RNA POLYMERASE IN COMPLEX WITH N-{3-[(BENZENECARBONYL)AMINO]-4-[(4- CHLOROPHENYL)METHOXY]BENZENE-1-CARBONYL}GLYCINE | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4wmc:C (GLU132) to (LEU196) OXA-48 COVALENT COMPLEX WITH AVIBACTAM INHIBITOR | OXA-48, CLASS D CARBAPENEMASE, AVIBACTAM, INHIBITOR, HYDROLASE
4wmc:D (GLU132) to (MET195) OXA-48 COVALENT COMPLEX WITH AVIBACTAM INHIBITOR | OXA-48, CLASS D CARBAPENEMASE, AVIBACTAM, INHIBITOR, HYDROLASE
1avm:A (LEU15) to (ASN81) THE CAMBIALISTIC SUPEROXIDE DISMUTASE (FE-SOD) OF P. SHERMANII COORDINATED BY AZIDE | OXIDOREDUCTASE, SOD, SUPEROXIDE DISMUTASE, PROPIONIBACTERIUM SHERMANII, AZIDE
1avm:B (LEU15) to (ASN81) THE CAMBIALISTIC SUPEROXIDE DISMUTASE (FE-SOD) OF P. SHERMANII COORDINATED BY AZIDE | OXIDOREDUCTASE, SOD, SUPEROXIDE DISMUTASE, PROPIONIBACTERIUM SHERMANII, AZIDE
4hb0:C (PRO922) to (ASN969) CRYSTAL STRUCTURE OF CRM1 INHIBITOR LEPTOMYCIN B IN COMPLEX WITH CRM1(K541Q,K542Q,R543S,K545Q,K548Q,K579Q)-RAN-RANBP1 | HEAT REPEAT, NUCLEAR EXPORT, RAN-RANBP1, LMB, LEPTOMYCIN B, PROTEIN TRANSPORT-ANTIBIOTIC COMPLEX
1b3q:A (LYS456) to (ASN518) CRYSTAL STRUCTURE OF CHEA-289, A SIGNAL TRANSDUCING HISTIDINE KINASE | HISTINE KINASE, SIGNAL TRANSDUCTION, CHEMOTAXIS, MULTI-DOMAINS PROTEIN, TRANSFERASE
1b3u:B (GLY274) to (VAL305) CRYSTAL STRUCTURE OF CONSTANT REGULATORY DOMAIN OF HUMAN PP2A, PR65ALPHA | SCAFFOLD PROTEIN, PP2A, PHOSPHORYLATION, HEAT REPEAT
3s27:H (GLU230) to (VAL275) THE CRYSTAL STRUCTURE OF SUCROSE SYNTHASE-1 FROM ARABIDOPSIS THALIANA AND ITS FUNCTIONAL IMPLICATIONS. | GLYCOSYLTRANSFERASE, SUCROSE METABOLISM, SUGAR ACCEPTOR COMPLEX, ROSSMANN FOLD, GT-B FOLD, UDP, FRUCTOSE, CYTOSOL, TRANSFERASE
3s29:A (GLU230) to (VAL275) THE CRYSTAL STRUCTURE OF SUCROSE SYNTHASE-1 FROM ARABIDOPSIS THALIANA AND ITS FUNCTIONAL IMPLICATIONS. | GLYCOSYLTRANSFERASE, SUCROSE METABOLISM, SUGAR ACCEPTOR COMPLEX, ROSSMANN FOLD, GT-B FOLD, UDP, FRUCTOSE, CYTOSOL, TRANSFERASE
3s29:C (GLU230) to (VAL275) THE CRYSTAL STRUCTURE OF SUCROSE SYNTHASE-1 FROM ARABIDOPSIS THALIANA AND ITS FUNCTIONAL IMPLICATIONS. | GLYCOSYLTRANSFERASE, SUCROSE METABOLISM, SUGAR ACCEPTOR COMPLEX, ROSSMANN FOLD, GT-B FOLD, UDP, FRUCTOSE, CYTOSOL, TRANSFERASE
3s29:H (GLU230) to (VAL275) THE CRYSTAL STRUCTURE OF SUCROSE SYNTHASE-1 FROM ARABIDOPSIS THALIANA AND ITS FUNCTIONAL IMPLICATIONS. | GLYCOSYLTRANSFERASE, SUCROSE METABOLISM, SUGAR ACCEPTOR COMPLEX, ROSSMANN FOLD, GT-B FOLD, UDP, FRUCTOSE, CYTOSOL, TRANSFERASE
1o5t:A (PHE260) to (PRO294) CRYSTAL STRUCTURE OF THE AMINOACYLATION CATALYTIC FRAGMENT OF HUMAN TRYPTOPHANYL-TRNA SYNTHETASE | ROSSMANN FOLD, FOUR HELIX BUNDLE, LIGASE
2brk:A (PRO479) to (TYR524) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH AN ALLOSTERIC INHIBITOR (COMPOUND 1) | TRANSFERASE, HEPATITIS C VIRUS, HCV, NS5B, POLYMERASE, RNA-DEPENDENT RNA- POLYMERASE, ALLOSTERIC INHIBITOR, ATP-BINDING
2brl:A (PRO479) to (ASN527) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH AN ALLOSTERIC INHIBITOR (COMPOUND 2) | TRANSFERASE, HEPATITIS C VIRUS, HCV, NS5B, POLYMERASE, RNA-DEPENDENT RNA- POLYMERASE, ALLOSTERIC INHIBITOR, NUCLEOTIDYLTRANSFERASE
3sdm:A (PRO1077) to (SER1115) STRUCTURE OF OLIGOMERIC KINASE/RNASE IRE1 IN COMPLEX WITH AN OLIGONUCLEOTIDE | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, COMPLEX, OLIGONUCLEOTIDE, TRANSFERASE, HYDROLASE
3sdm:B (PRO1077) to (SER1115) STRUCTURE OF OLIGOMERIC KINASE/RNASE IRE1 IN COMPLEX WITH AN OLIGONUCLEOTIDE | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, COMPLEX, OLIGONUCLEOTIDE, TRANSFERASE, HYDROLASE
3sdm:C (PRO1077) to (SER1115) STRUCTURE OF OLIGOMERIC KINASE/RNASE IRE1 IN COMPLEX WITH AN OLIGONUCLEOTIDE | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, COMPLEX, OLIGONUCLEOTIDE, TRANSFERASE, HYDROLASE
3sdm:D (PRO1077) to (SER1115) STRUCTURE OF OLIGOMERIC KINASE/RNASE IRE1 IN COMPLEX WITH AN OLIGONUCLEOTIDE | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, COMPLEX, OLIGONUCLEOTIDE, TRANSFERASE, HYDROLASE
3sdm:E (PRO1077) to (SER1115) STRUCTURE OF OLIGOMERIC KINASE/RNASE IRE1 IN COMPLEX WITH AN OLIGONUCLEOTIDE | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, COMPLEX, OLIGONUCLEOTIDE, TRANSFERASE, HYDROLASE
3sdm:F (PRO1077) to (SER1115) STRUCTURE OF OLIGOMERIC KINASE/RNASE IRE1 IN COMPLEX WITH AN OLIGONUCLEOTIDE | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, COMPLEX, OLIGONUCLEOTIDE, TRANSFERASE, HYDROLASE
3sdm:G (PRO1077) to (SER1115) STRUCTURE OF OLIGOMERIC KINASE/RNASE IRE1 IN COMPLEX WITH AN OLIGONUCLEOTIDE | KINASE, RNASE, RIBONUCLEASE, HAC1, XBP1, SPLICING, RNA, UPR, UNFOLDED PROTEIN RESPONSE, OLIGOMER, COMPLEX, OLIGONUCLEOTIDE, TRANSFERASE, HYDROLASE
3ffz:B (GLY257) to (GLY308) DOMAIN ORGANIZATION IN CLOSTRIDIUM BUTULINUM NEUROTOXIN TYPE E IS UNIQUE: ITS IMPLICATION IN FASTER TRANSLOCATION | BOTULINUM NEUROTOXIN SEROTYPE E, BOTULISM, DOMAIN ORGANIZATION, ENDOPEPTIDASE, TRANSLOCATION, HYDROLASE, MEMBRANE, METAL-BINDING, METALLOPROTEASE, NEUROTOXIN, PROTEASE, SECRETED, TOXIN, TRANSMEMBRANE, ZINC
2prz:D (PRO73) to (ILE99) S. CEREVISIAE OROTATE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH OMP | ALPHA BETA, OPRTASE-OMP COMPLEX, TRANSFERASE
2ckp:A (THR371) to (LEU455) CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE ALPHA-2 IN COMPLEX WITH ADP | KINASE, TRANSFERASE, CHOLINE KINASE, PHOSPHATYDILCHOLINE
2ckp:B (THR371) to (LEU455) CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE ALPHA-2 IN COMPLEX WITH ADP | KINASE, TRANSFERASE, CHOLINE KINASE, PHOSPHATYDILCHOLINE
4ip7:D (GLY21) to (LEU45) STRUCTURE OF THE S12D VARIANT OF HUMAN LIVER PYRUVATE KINASE IN COMPLEX WITH CITRATE AND FBP. | KINASE, GLYCOLYSIS, ALLOSTERIC, PHOSPHORYLATION MIMIC, LIVER, TRANSFERASE
2qpd:A (LYS18) to (LEU59) AN UNEXPECTED OUTCOME OF SURFACE-ENGINEERING AN INTEGRAL MEMBRANE PROTEIN: IMPROVED CRYSTALLIZATION OF CYTOCHROME BA3 OXIDASE FROM THERMUS THERMOPHILUS | CYTOCHROME BA3 OXIDASE, HEME,INTEGRAL MEMBRANE PROTEIN, ELECTRON TRANSPORT, HYDROGEN ION TRANSPORT, ION TRANSPORT, IRON, METAL- BINDING, OXIDOREDUCTASE, RESPIRATORY CHAIN, TRANSMEMBRANE, TRANSPORT, FORMYLATION
2qpe:A (GLU17) to (LEU58) AN UNEXPECTED OUTCOME OF SURFACE-ENGINEERING AN INTEGRAL MEMBRANE PROTEIN: IMPROVED CRYSTALLIZATION OF CYTOCHROME BA3 OXIDASE FROM THERMUS THERMOPHILUS | CYTOCHROME BA3 OXIDASE, HEME,INTEGRAL MEMBRANE PROTEIN, ELECTRON TRANSPORT, HYDROGEN ION TRANSPORT, ION TRANSPORT, IRON, METAL- BINDING, OXIDOREDUCTASE, RESPIRATORY CHAIN, TRANSMEMBRANE, TRANSPORT, FORMYLATION
2qu0:A (SER3) to (PRO44) CRYSTAL STRUCTURE DETERMINATION OF SHEEP METHEMOGLOBIN AT 2.7 ANGSTROM RESOLUTION | HEMOGLOBIN, OVIS ARIES, HANGING DROP, QUARTERNARY STRUCTURE, HEME, IRON, METAL-BINDING, POLYMORPHISM, TRANSPORT, OXYGEN STORAGE, OXYGEN TRANSPORT
3gol:B (SER478) to (PHE526) HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR (R)- 11D | 1,5-BENZODIAZEPINE, HCV POLYMERASE, NS5B, MEDICINAL CHEMISTRY, 1B-J4, TRANSFERASE
2r45:B (GLY52) to (PHE83) CRYSTAL STRUCTURE OF ESCHERICHIA COLI GLYCEROL-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH 2-PHOSPHO-D-GLYCERIC ACID | GLPD, OXIDOREDUCTASE
3tlx:C (GLU3) to (SER51) CRYSTAL STRUCTURE OF PF10_0086, ADENYLATE KINASE FROM PLASMODIUM FALCIPARUM | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, ROSSMANN FOLD, TRANSFERASE, ATP BINDING, PHOSPHORYLATION
2dxs:B (SER478) to (TYR524) CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE COMPLEXED WITH A TETRACYCLIC INHIBITOR | HCV, NS5B, RNA POLYMERASE, TRANSFERASE/TRANSFERASE INHIBITOR COMPLEX
3h1v:X (TYR297) to (GLY356) HUMAN GLUCOKINASE IN COMPLEX WITH A SYNTHETIC ACTIVATOR | GLUCOKINASE, DIABETES, ALLOSTERIC ACTIVATOR, ALTERNATIVE SPLICING, ATP-BINDING, DIABETES MELLITUS, DISEASE MUTATION, GLYCOLYSIS, KINASE, NUCLEOTIDE-BINDING, POLYMORPHISM, TRANSFERASE
3twj:B (ARG10) to (TYR59) RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH RKI1447 | KINASE, DIMER, DIMERIZATION, MYOSIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3twj:D (ARG10) to (LYS60) RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH RKI1447 | KINASE, DIMER, DIMERIZATION, MYOSIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4yii:U (ASP127) to (GLN173) STRUCTURE OF AN APC2-UBCH10 COMPLEX REVEALS DISTINCTIVE CULLIN-RING LIGASE MECHANISM FOR ANAPHASE-PROMOTING COMPLEX/CYCLOSOME | LIGASE-CELL CYCLE COMPLEX
3tyq:A (SER478) to (ARG523) SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3tyq:B (SER478) to (ARG523) SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3h5s:A (SER478) to (LYS523) HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
3h5u:B (SER478) to (LYS523) HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR 1 | HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
4jsp:B (ASN2003) to (GLU2059) STRUCTURE OF MTORDELTAN-MLST8-ATPGAMMAS-MG COMPLEX | KINASE, TRANSFERASE
4jsp:A (ASN2003) to (GLU2059) STRUCTURE OF MTORDELTAN-MLST8-ATPGAMMAS-MG COMPLEX | KINASE, TRANSFERASE
3u4o:B (SER478) to (ARG523) NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE C2 ACYL SULFONAMIDES | NUCLEOTIDYL TRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jy0:B (SER478) to (PHE526) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 3 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1fdo:A (THR477) to (THR516) OXIDIZED FORM OF FORMATE DEHYDROGENASE H FROM E. COLI | OXIDOREDUCTASE, SELENIUM, SELENOCYSTEINE, SECYS, MOLYBDENUM, MOLYBDOPTERIN, MPT, MOLYBDOPTERIN GUANINE DINUCLEOTIDE, MGD, IRON SULFUR CLUSTER, FE4S4, FORMATE, DEHYDROGENASE, ANAEROBIC
1r8j:A (LEU111) to (LEU164) CRYSTAL STRUCTURE OF CIRCADIAN CLOCK PROTEIN KAIA FROM SYNECHOCOCCUS ELONGATUS | KAIA, CIRCADIAN CLOCK PROTEIN
1fof:A (GLY128) to (VAL193) CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 | BETA-LACTAMASE, CLASS-D, OXACILLINASE, OXA-10, COBALT,, HYDROLASE
1fof:B (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 | BETA-LACTAMASE, CLASS-D, OXACILLINASE, OXA-10, COBALT,, HYDROLASE
2v8w:A (ASN118) to (ASP148) CRYSTALLOGRAPHIC AND MASS SPECTROMETRIC CHARACTERISATION OF EIF4E WITH N7-CAP DERIVATIVES | TRANSLATION, PHOSPHORYLATION, INITIATION FACTOR, CAP, EIF4E, M7GTP, 4E-BP1, RNA-BINDING, ACETYLATION, HOST-VIRUS INTERACTION, PROTEIN SYNTHESIS INHIBITOR, PROTEIN BIOSYNTHESIS, TRANSLATION REGULATION
2v8x:A (ASN118) to (ASP148) CRYSTALLOGRAPHIC AND MASS SPECTROMETRIC CHARACTERISATION OF EIF4E WITH N7-CAP DERIVATIVES | TRANSLATION, PHOSPHORYLATION, INITIATION FACTOR, CAP, EIF4E, 7BNGMP, 4E-BP1, RNA-BINDING, ACETYLATION, HOST-VIRUS INTERACTION, PROTEIN SYNTHESIS INHIBITOR, PROTEIN BIOSYNTHESIS, TRANSLATION REGULATION
2v8y:A (ASN118) to (ASP148) CRYSTALLOGRAPHIC AND MASS SPECTROMETRIC CHARACTERISATION OF EIF4E WITH N7-CAP DERIVATIVES | TRANSLATION, PHOSPHORYLATION, INITIATION FACTOR, CAP, EIF4E, 7BNGMP, 4E-BP1, RNA-BINDING, ACETYLATION, HOST-VIRUS INTERACTION, PROTEIN SYNTHESIS INHIBITOR, PROTEIN BIOSYNTHESIS, TRANSLATION REGULATION
4k82:A (LEU69) to (LYS124) CRYSTAL STRUCTURE OF LV-RANASPUMIN (LV-RSN-1) FROM THE FOAM NEST OF LEPTODACTYLUS VASTUS, MONOCLINIC CRYSTAL FORM | ALPHA-HELICAL, SURFACTANT PROTEIN, FOAM NEST, FROG, AMPHIBIAN, STRUCTURAL PROTEIN
3hop:A (THR167) to (PRO211) STRUCTURE OF THE ACTIN-BINDING DOMAIN OF HUMAN FILAMIN A | CALPONIN HOMOLOGY DOMAIN, ACTIN BINDING DOMAIN, ACETYLATION, ACTIN-BINDING, ALTERNATIVE SPLICING, CYTOPLASM, CYTOSKELETON, DISEASE MUTATION, PHOSPHOPROTEIN, POLYMORPHISM, STRUCTURAL PROTEIN
1g7d:A (SER233) to (LYS257) NMR STRUCTURE OF ERP29 C-DOMAIN | ALPHA HELICAL PROTEIN, CHAPERONE
4z3w:A (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH 1,5 DIENOYL-COA | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3w:B (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH 1,5 DIENOYL-COA | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3w:C (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH 1,5 DIENOYL-COA | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
4z3w:D (PRO605) to (GLY648) ACTIVE SITE COMPLEX BAMBC OF BENZOYL COENZYME A REDUCTASE IN COMPLEX WITH 1,5 DIENOYL-COA | AROMATICS, REDUCTASE, BENZOYL-COA, ANAEROBIC, OXIDOREDUCTASE
3hvo:A (SER478) to (TYR524) STRUCTURE OF THE GENOTYPE 2B HCV POLYMERASE BOUND TO A NNI | VIRAL POLYMERASE, ATP-BINDING, HYDROLASE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE
3hvo:B (SER478) to (TYR524) STRUCTURE OF THE GENOTYPE 2B HCV POLYMERASE BOUND TO A NNI | VIRAL POLYMERASE, ATP-BINDING, HYDROLASE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE
4kpm:D (GLN313) to (GLY360) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF RPFB FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH TRINAG | ALPHA-BETA, CELL WALL HYDROLASE, HYDROLASE
3v8s:A (GLU8) to (TYR59) HUMAN RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH INDAZOLE DERIVATIVE (COMPOUND 18) | KINASE, DIMERIZATION, MYOSIN, TRANSFERASE, INHIBITOR, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3v8s:B (THR9) to (TYR59) HUMAN RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH INDAZOLE DERIVATIVE (COMPOUND 18) | KINASE, DIMERIZATION, MYOSIN, TRANSFERASE, INHIBITOR, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3v8s:C (THR9) to (TYR59) HUMAN RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH INDAZOLE DERIVATIVE (COMPOUND 18) | KINASE, DIMERIZATION, MYOSIN, TRANSFERASE, INHIBITOR, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3v8s:D (THR9) to (TYR59) HUMAN RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH INDAZOLE DERIVATIVE (COMPOUND 18) | KINASE, DIMERIZATION, MYOSIN, TRANSFERASE, INHIBITOR, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2g3v:B (ASP71) to (LEU122) CRYSTAL STRUCTURE OF CAGS (HP0534, CAG13) FROM HELICOBACTER PYLORI | HELICOBACTER PYLORI, PATHOGENICITY ISLAND, TYPE IV SECRETION SYSTEM, UNKNOWN FUNCTION
3i5k:A (SER478) to (ARG523) CRYSTAL STRUCTURE OF THE NS5B POLYMERASE FROM HEPATITIS C VIRUS (HCV) STRAIN JFH1 | RDRP STRUCTURE (FINGERS, PALM, THUMB DOMAINS), APOPTOSIS, ATP- BINDING, CAPSID PROTEIN, CELL MEMBRANE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3i5k:B (SER478) to (ARG523) CRYSTAL STRUCTURE OF THE NS5B POLYMERASE FROM HEPATITIS C VIRUS (HCV) STRAIN JFH1 | RDRP STRUCTURE (FINGERS, PALM, THUMB DOMAINS), APOPTOSIS, ATP- BINDING, CAPSID PROTEIN, CELL MEMBRANE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3i5k:C (SER478) to (ARG523) CRYSTAL STRUCTURE OF THE NS5B POLYMERASE FROM HEPATITIS C VIRUS (HCV) STRAIN JFH1 | RDRP STRUCTURE (FINGERS, PALM, THUMB DOMAINS), APOPTOSIS, ATP- BINDING, CAPSID PROTEIN, CELL MEMBRANE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
3i5k:D (SER478) to (ARG523) CRYSTAL STRUCTURE OF THE NS5B POLYMERASE FROM HEPATITIS C VIRUS (HCV) STRAIN JFH1 | RDRP STRUCTURE (FINGERS, PALM, THUMB DOMAINS), APOPTOSIS, ATP- BINDING, CAPSID PROTEIN, CELL MEMBRANE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION
4kx7:A (ASP841) to (ASN874) CRYSTAL STRUCTURE OF HUMAN AMINOPEPTIDASE A | ZINC-AMINOPEPTIDASE FOLD, HYDROLASE
4kzm:A (ALA549) to (LEU596) CRYSTAL STRUCTURE OF TR3 LBD S553A MUTANT | ORPHAN NUCLEAR RECEPTOR, TRANSCRIPTION
1t3c:B (GLY256) to (LYS305) CLOSTRIDIUM BOTULINUM TYPE E CATALYTIC DOMAIN E212Q MUTANT | CLOSTRIDIUM BOTULINUM, CATALYTIC DOMAIN, E212Q MUTANT, LIGHT CHAIN, HYDROLASE, TOXIN
2w31:B (ASP15) to (LEU53) GLOBIN DOMAIN OF GEOBACTER SULFURREDUCENS GLOBIN-COUPLED SENSOR | OXYGEN TRANSPORT, GEOBACTER SULFURREDUCENS, HEXACOORDINATION, GLOBIN COUPLED SENSOR
3ihy:A (ASP388) to (GLY414) HUMAN PIK3C3 CRYSTAL STRUCTURE | ALPHA/BETA PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC, ATP-BINDING, KINASE, MANGANESE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE
3ihy:B (ASP388) to (GLY414) HUMAN PIK3C3 CRYSTAL STRUCTURE | ALPHA/BETA PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC, ATP-BINDING, KINASE, MANGANESE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE
3ihy:C (ASP389) to (GLY414) HUMAN PIK3C3 CRYSTAL STRUCTURE | ALPHA/BETA PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC, ATP-BINDING, KINASE, MANGANESE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE
3ihy:D (ASP503) to (GLU562) HUMAN PIK3C3 CRYSTAL STRUCTURE | ALPHA/BETA PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC, ATP-BINDING, KINASE, MANGANESE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE
3ihy:E (ASP389) to (GLY414) HUMAN PIK3C3 CRYSTAL STRUCTURE | ALPHA/BETA PROTEIN, STRUCTURAL GENOMICS, SGC STOCKHOLM, STRUCTURAL GENOMICS CONSORTIUM, SGC, ATP-BINDING, KINASE, MANGANESE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE
1h8y:B (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-13 IN COMPLEX WITH MEROPENEM | HYDROLASE, BETA-LACTAMASE, CLASS D, OXA-13, MEROPENEM, ACYL- ENZYME
2w58:B (PRO1123) to (TYR1155) CRYSTAL STRUCTURE OF THE DNAI | DNAI, HELICASE, ATP-BINDING, NUCLEOTIDE-BINDING, HYDROLASE
2wa5:A (THR140) to (PRO184) CRYSTAL STRUCTURE OF HUMAN FILAMIN B ACTIN BINDING DOMAIN AT 1.9 ANGSTROMS RESOLUTION | DISEASE MUTATION, SKELETAL DYSPLASIA, STRUCTURAL PROTEIN, ACTIN-CROSSLINKING, MYOGENESIS, CYTOSKELETON, ACTIN-BINDING, CALPONIN HOMOLOGY DOMAIN, PHOSPHOPROTEIN, DIFFERENTIATION, ATELOSTEOGENESIS, MUTANT, FILAMIN, DWARFISM, CH DOMAIN, DEVELOPMENTAL PROTEIN
2wgw:A (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 V117T MUTANT AT PH 8.0 | ANTIBIOTIC RESISTANCE, TRANSPOSABLE, HYDROLASE
2wgw:B (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE OXA-10 V117T MUTANT AT PH 8.0 | ANTIBIOTIC RESISTANCE, TRANSPOSABLE, HYDROLASE
2who:A (SER478) to (TYR524) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR | TRANSFERASE, RNA REPLICATION, ENVELOPE PROTEIN, HEPATITIS C VIRUS, ENDOPLASMIC RETICULUM, NON NUCLEOSIDE INHIBITOR, VIRAL PROTEIN, METAL-BINDING, TRANSMEMBRANE, POLYMERASE, ATP-BINDING, GENOTYPE 1B, RNA-BINDING, RNA-DEPENDENT RNA POLYMERASE, NNI, HCV, NS5B, MEMBRANE, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, ALLOSTERIC INHIBITOR, RNA-DIRECTED RNA POLYMERASE
2who:B (SER478) to (ASN527) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR | TRANSFERASE, RNA REPLICATION, ENVELOPE PROTEIN, HEPATITIS C VIRUS, ENDOPLASMIC RETICULUM, NON NUCLEOSIDE INHIBITOR, VIRAL PROTEIN, METAL-BINDING, TRANSMEMBRANE, POLYMERASE, ATP-BINDING, GENOTYPE 1B, RNA-BINDING, RNA-DEPENDENT RNA POLYMERASE, NNI, HCV, NS5B, MEMBRANE, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, ALLOSTERIC INHIBITOR, RNA-DIRECTED RNA POLYMERASE
5a0u:A (GLY502) to (GLU568) STRUCTURE OF CUTC CHOLINE LYASE CHOLINE BOUND FORM FROM KLEBSIELLA PNEUMONIAE. | LYASE, CUTC, CHOLINE TMA LYASE, GLYCYL RADICAL ENZYME
5a0u:C (GLY502) to (ILE534) STRUCTURE OF CUTC CHOLINE LYASE CHOLINE BOUND FORM FROM KLEBSIELLA PNEUMONIAE. | LYASE, CUTC, CHOLINE TMA LYASE, GLYCYL RADICAL ENZYME
5a0u:E (GLY502) to (ILE534) STRUCTURE OF CUTC CHOLINE LYASE CHOLINE BOUND FORM FROM KLEBSIELLA PNEUMONIAE. | LYASE, CUTC, CHOLINE TMA LYASE, GLYCYL RADICAL ENZYME
5a0u:F (GLY502) to (ILE534) STRUCTURE OF CUTC CHOLINE LYASE CHOLINE BOUND FORM FROM KLEBSIELLA PNEUMONIAE. | LYASE, CUTC, CHOLINE TMA LYASE, GLYCYL RADICAL ENZYME
5a0u:G (GLY502) to (ILE534) STRUCTURE OF CUTC CHOLINE LYASE CHOLINE BOUND FORM FROM KLEBSIELLA PNEUMONIAE. | LYASE, CUTC, CHOLINE TMA LYASE, GLYCYL RADICAL ENZYME
4lrl:B (THR289) to (LEU324) STRUCTURE OF AN ENTEROCOCCUS FAECALIS HD-DOMAIN PROTEIN COMPLEXED WITH DGTP AND DTTP | STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, HD DOMAIN, PHOSPHOHYDROLASE, DNTPASE, ALLOSTERIC REGULATION, METAL BINDING PROTEIN, HYDROLASE
4m2i:B (PRO39) to (ASP67) CRYSTAL STRUCTURE OF NON-HEME IRON OXYGENASE ORFP IN COMPLEX WITH FE | HYDROXYLASE, FE BINDING, OXIDOREDUCTASE
3wc9:B (SER38) to (ASN99) THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND, FSPP | ISOPRENOIDS, DRUG DISCOVERY, HUMAN SQUALENE SYNTHASE, TRANSFERASE, FSPP
3wcm:C (SER37) to (ASN99) THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND, ER119884 | ISOPRENOIDS, DRUG DISCOVERY, HUMAN SQUALENE SYNTHASE, TRANSFERASE, ER119884
3wcu:A (ILE4) to (PHE46) THE STRUCTURE OF A DEOXYGENATED 400 KDA HEMOGLOBIN PROVIDES A MORE ACCURATE DESCRIPTION OF THE COOPERATIVE MECHANISM OF GIANT HEMOGLOBINS: DEOXYGENATED FORM | GLOBIN FOLD, OXYGEN TRANSPORT, OXYGEN BINDING, BLOOD
3wcu:E (ILE4) to (PHE46) THE STRUCTURE OF A DEOXYGENATED 400 KDA HEMOGLOBIN PROVIDES A MORE ACCURATE DESCRIPTION OF THE COOPERATIVE MECHANISM OF GIANT HEMOGLOBINS: DEOXYGENATED FORM | GLOBIN FOLD, OXYGEN TRANSPORT, OXYGEN BINDING, BLOOD
2ihb:A (SER62) to (ALA114) CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF HUMAN RGS10 AND ACTIVATED GI ALPHA 3 | G PROTEIN SIGNALLING, RGS, HETEROTRIMERIC G PROTEIN, SIGNALLING COMPLEX, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, SIGNALING PROTEIN
4mdk:C (VAL120) to (GLY180) CDC34-UBIQUITIN-CC0651 COMPLEX | UBIQUITIN CONJUGATING ENZYME DOMAIN, E2 LIGASE INHIBITOR, LIGASE- LIGASE INHIBITOR COMPLEX
2x6i:A (ASP391) to (ILE420) THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH PIK-90 | TRANSFERASE
2iwc:A (ARG452) to (MET515) BENZYLPENICILLOYL-ACYLATED MECR1 EXTRACELLULAR ANTIBIOTIC- SENSOR DOMAIN. | BACTERIAL ANTIBIOTIC RESISTANCE, MRSA, BETA-LACTAMASE, BENZYLPENICILLIN, ANTIBIOTIC RESISTANCE, METHICILLIN RESISTANCE, BETA-LACTAMIC ANTIBIOTICS, PENICILLIN-BINDING PROTEIN
3won:B (ALA322) to (ALA388) CRYSTAL STRUCTURE OF THE DAP BII DIPEPTIDE COMPLEX III | CHYMOTRYPSIN FOLD, S46 PEPTIDASE, HYDROLASE
2xhv:A (SER478) to (ARG523) HCV-J4 NS5B POLYMERASE POINT MUTANT ORTHORHOMBIC CRYSTAL FORM | REPLICATION, TRANSCRIPTION, TRANSFERASE
2xhv:B (SER478) to (ARG523) HCV-J4 NS5B POLYMERASE POINT MUTANT ORTHORHOMBIC CRYSTAL FORM | REPLICATION, TRANSCRIPTION, TRANSFERASE
4mz4:A (SER478) to (ARG523) DISCOVERY OF AN IRREVERSIBLE HCV NS5B POLYMERASE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mz4:B (SER478) to (ARG523) DISCOVERY OF AN IRREVERSIBLE HCV NS5B POLYMERASE INHIBITOR | RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3zdu:A (PRO181) to (SER231) CRYSTAL STRUCTURE OF THE HUMAN CDKL3 KINASE DOMAIN | TRANSFERASE, PHOSPHO-MIMETIC
2xwy:A (PRO479) to (ASN527) STRUCTURE OF MK-3281, A POTENT NON-NUCLEOSIDE FINGER-LOOP INHIBITOR, IN COMPLEX WITH THE HEPATITIS C VIRUS NS5B POLYMERASE | TRANSFERASE, ALLOSTERIC INHIBITOR, NUCLEOTIDYLTRANSFERASE
1k57:A (GLU129) to (VAL193) OXA 10 CLASS D BETA-LACTAMASE AT PH 6.0 | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k57:B (GLU129) to (VAL193) OXA 10 CLASS D BETA-LACTAMASE AT PH 6.0 | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k57:C (GLU129) to (VAL193) OXA 10 CLASS D BETA-LACTAMASE AT PH 6.0 | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
1k57:D (GLU129) to (VAL193) OXA 10 CLASS D BETA-LACTAMASE AT PH 6.0 | BETA-LACTAMASE, ANTIBIOTIC RESISTANCE, CARBAMYLATION, HYDROLASE
2yi0:A (TYR38) to (GLY73) STRUCTURAL CHARACTERIZATION OF 5-ARYL-4-(5-SUBSTITUTED-2-4- DIHYDROXYPHENYL)-1,2,3-THIADIAZOLE HSP90 INHIBITORS. | CHAPERONE, ATPASE, INHIBITORS
4o1p:A (PRO696) to (HIS723) CRYSTAL STRUCTURE OF RNASE L IN COMPLEX WITH 2-5A AND AMP-PNP | ANKYRIN REPEAT-KINASE-RNASE, RNA CLEAVAGE, 2-5A, TRANSFERASE, HYDROLASE
4o1p:B (PRO696) to (HIS723) CRYSTAL STRUCTURE OF RNASE L IN COMPLEX WITH 2-5A AND AMP-PNP | ANKYRIN REPEAT-KINASE-RNASE, RNA CLEAVAGE, 2-5A, TRANSFERASE, HYDROLASE
4o1p:C (PRO696) to (HIS723) CRYSTAL STRUCTURE OF RNASE L IN COMPLEX WITH 2-5A AND AMP-PNP | ANKYRIN REPEAT-KINASE-RNASE, RNA CLEAVAGE, 2-5A, TRANSFERASE, HYDROLASE
4o1p:D (PRO696) to (HIS723) CRYSTAL STRUCTURE OF RNASE L IN COMPLEX WITH 2-5A AND AMP-PNP | ANKYRIN REPEAT-KINASE-RNASE, RNA CLEAVAGE, 2-5A, TRANSFERASE, HYDROLASE
1lhs:A (SER3) to (PHE43) LOGGERHEAD SEA TURTLE MYOGLOBIN (AQUO-MET) | OXYGEN STORAGE
3k4g:C (THR263) to (GLY311) CRYSTAL STRUCTURE OF E. COLI RNA POLYMERASE ALPHA SUBUNIT C-TERMINAL DOMAIN | BACTERIAL TRANSCRIPTION REGULATION, DNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, TRANSFERASE
3k4g:F (THR263) to (GLY311) CRYSTAL STRUCTURE OF E. COLI RNA POLYMERASE ALPHA SUBUNIT C-TERMINAL DOMAIN | BACTERIAL TRANSCRIPTION REGULATION, DNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, TRANSFERASE
3k4g:G (THR263) to (GLY311) CRYSTAL STRUCTURE OF E. COLI RNA POLYMERASE ALPHA SUBUNIT C-TERMINAL DOMAIN | BACTERIAL TRANSCRIPTION REGULATION, DNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, TRANSFERASE
2o1o:B (SER301) to (ILE355) CRYPTOSPORIDIUM PARVUM PUTATIVE POLYPRENYL PYROPHOSPHATE SYNTHASE (CGD4_2550) IN COMPLEX WITH RISEDRONATE. | PUTATIVE POLYPRENYL PYROPHOSPHATE SYNTHASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, UNKNOWN FUNCTION
4ad7:A (CYS32) to (ASN137) CRYSTAL STRUCTURE OF FULL-LENGTH N-GLYCOSYLATED HUMAN GLYPICAN-1 | MEMBRANE PROTEIN, PROTEOGLYCAN, GLYCOSAMINOGLYCANS, HEPARAN SULFATE, HELICAL BUNDLE, GLYCOPROTEIN, SUGAR BINDING PROTEIN
4aep:A (SER478) to (ARG523) HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 1.8 ANGSTROM | TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING
1y8x:A (ILE125) to (GLY170) STRUCTURAL BASIS FOR RECRUITMENT OF UBC12 BY AN E2-BINDING DOMAIN IN NEDD8'S E1 | UBIQUITIN-CONJUGATING ENZYME E2 M, LIGASE
3kpu:A (ALA24) to (PRO50) CRYSTAL STRUCTURE OF HPNMT IN COMPLEX ADOHCY AND 4-QUINOLINOL | METHYLTRANSFERASE, FRAGMENT SCREENING, CATECHOLAMINE BIOSYNTHESIS, S- ADENOSYL-L-METHIONINE, TRANSFERASE
4ais:A (LYS489) to (GLN543) A COMPLEX STRUCTURE OF BTGH84 | HYDROLASE, INHIBITOR
1yvx:A (THR478) to (PHE526) HEPATITIS C VIRUS RNA POLYMERASE GENOTYPE 2A IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR | NS5B POLYMERASE GENOTYPE 2A, NON-NUCLEOSIDE INHIBITOR, VIRAL PROTEIN
1z6t:A (ASP479) to (LEU503) STRUCTURE OF THE APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 BOUND TO ADP | APAF-1, CASPASE ACTIVATION, ADP, NUCLEOTIDE BINDING, CARD, APOPTOSIS
1z6t:D (ASP479) to (LEU503) STRUCTURE OF THE APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 BOUND TO ADP | APAF-1, CASPASE ACTIVATION, ADP, NUCLEOTIDE BINDING, CARD, APOPTOSIS
3lq3:A (THR305) to (LEU388) CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE BETA IN COMPLEX WITH PHOSPHORYLATED HEMICHOLINIUM-3 AND ADENOSINE NUCLEOTIDE | NON-PROTEIN KINASE, CHOLINE KINASE, STRUCTURAL GENOMICS CONSORTIUM, SGC, HEMICHOLINIUM-3, PHOSPHORYLATION, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOLIPID BIOSYNTHESIS, PHOSPHOPROTEIN, TRANSFERASE
4qn8:A (LEU3) to (ASP32) THE CRYSTAL STRUCTURE OF AN EFFECTOR PROTEIN VIPE FROM LEGIONELLA PNEUMOPHILA SUBSP. PNEUMOPHILA STR. PHILADELPHIA 1 | STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, SIGNALING PROTEIN
4qn8:B (LEU3) to (LEU31) THE CRYSTAL STRUCTURE OF AN EFFECTOR PROTEIN VIPE FROM LEGIONELLA PNEUMOPHILA SUBSP. PNEUMOPHILA STR. PHILADELPHIA 1 | STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, SIGNALING PROTEIN
5eqe:A (THR371) to (LEU455) CRYSTAL STRUCTURE OF CHOLINE KINASE ALPHA-1 BOUND BY [4-[(4-METHYL-1, 4-DIAZEPAN-1-YL)METHYL]PHENYL]METHANAMINE (COMPOUND 11) | KINASE, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4qs8:A (TYR322) to (GLU383) ARABIDOPSIS HEXOKINASE 1 (ATHXK1) STRUCTURE IN LIGAND-FREE FORM | HEXOKINASE, ATP-DEPENDENT, SUGAR SENSOR, TRANSFERASE
4bgq:A (SER191) to (ASN241) CRYSTAL STRUCTURE OF THE HUMAN CDKL5 KINASE DOMAIN | TRANSFERASE, PHOSPHO-MIMETIC, KINASE
3bsx:A (SER830) to (LEU886) CRYSTAL STRUCTURE OF HUMAN PUMILIO 1 IN COMPLEX WITH PUF5 RNA | PROTEIN-RNA COMPLEX, PHOSPHOPROTEIN, RNA-BINDING, TRANSLATION REGULATION, RNA BINDING PROTEIN-RNA COMPLEX
5fiq:A (SER247) to (LYS301) EXONUCLEASE DOMAIN-CONTAINING 1 (EXD1) IN THE NATIVE CONFORMATION | HYDROLASE, EXONUCLEASE, PIRNA BIOGENESIS, DIMER, RNA BINDING
5fiq:C (SER247) to (LYS301) EXONUCLEASE DOMAIN-CONTAINING 1 (EXD1) IN THE NATIVE CONFORMATION | HYDROLASE, EXONUCLEASE, PIRNA BIOGENESIS, DIMER, RNA BINDING
5fiq:E (VAL248) to (LYS301) EXONUCLEASE DOMAIN-CONTAINING 1 (EXD1) IN THE NATIVE CONFORMATION | HYDROLASE, EXONUCLEASE, PIRNA BIOGENESIS, DIMER, RNA BINDING
5fiq:G (VAL248) to (LYS301) EXONUCLEASE DOMAIN-CONTAINING 1 (EXD1) IN THE NATIVE CONFORMATION | HYDROLASE, EXONUCLEASE, PIRNA BIOGENESIS, DIMER, RNA BINDING
5fiq:I (SER247) to (LYS301) EXONUCLEASE DOMAIN-CONTAINING 1 (EXD1) IN THE NATIVE CONFORMATION | HYDROLASE, EXONUCLEASE, PIRNA BIOGENESIS, DIMER, RNA BINDING
3cde:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, ATP-BINDING, HOST-VIRUS INTERACTION, HYDROLASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION
3cde:B (SER478) to (TYR524) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, ATP-BINDING, HOST-VIRUS INTERACTION, HYDROLASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION
4re8:A (ALA218) to (LEU265) CRYSTAL STRUCTURE OF TR3 LBD IN COMPLEX WITH MOLECULE 5 | LBD, TRANSCRIPTION
5fl1:A (LYS489) to (GLN543) STRUCTURE OF A HYDROLASE WITH AN INHIBITOR | HYDROLASE
5fl1:B (LYS489) to (SER545) STRUCTURE OF A HYDROLASE WITH AN INHIBITOR | HYDROLASE
3cj2:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS | DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC
5fnd:A (TYR38) to (GLY73) DYNAMIC UNDOCKING AND THE QUASI-BOUND STATE AS TOOLS FOR DRUG DESIGN | HSP90, DRUG DESIGN, CHAPERONE, ONCOLOGY
4rid:A (CYS538) to (LEU641) HUMAN FAN1 NUCLEASE | NUCLEASE, HYDROLASE
4rid:B (CYS538) to (LEU641) HUMAN FAN1 NUCLEASE | NUCLEASE, HYDROLASE
5fq9:B (GLU129) to (VAL193) CRYSTAL STRUCTURE OF THE OXA10 WITH 1C | HYDROLASE, ANTIBIOTIC RESISTANCE
3co9:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, NUCLEOTIDE BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSFERASE, ANTIVIRAL, HYDROLASE, NUCLEOTIDE-BINDING
3co9:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, NUCLEOTIDE BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSFERASE, ANTIVIRAL, HYDROLASE, NUCLEOTIDE-BINDING
4rpl:B (GLY105) to (LEU148) CRYSTAL STRUCTURE OF MICOBACTERIUM TUBERCULOSIS UDP-GALACTOPYRANOSE MUTASE IN COMPLEX WITH TETRAFLUORINATED SUBSTRATE ANALOG UDP-F4-GALP | UDP-GALACTOPYRANOSE MUTASE, MTUGM, FLAVOENZYME, FAD, ISOMERASE
4rpl:A (GLY105) to (LEU148) CRYSTAL STRUCTURE OF MICOBACTERIUM TUBERCULOSIS UDP-GALACTOPYRANOSE MUTASE IN COMPLEX WITH TETRAFLUORINATED SUBSTRATE ANALOG UDP-F4-GALP | UDP-GALACTOPYRANOSE MUTASE, MTUGM, FLAVOENZYME, FAD, ISOMERASE
4rpl:C (GLY105) to (LEU148) CRYSTAL STRUCTURE OF MICOBACTERIUM TUBERCULOSIS UDP-GALACTOPYRANOSE MUTASE IN COMPLEX WITH TETRAFLUORINATED SUBSTRATE ANALOG UDP-F4-GALP | UDP-GALACTOPYRANOSE MUTASE, MTUGM, FLAVOENZYME, FAD, ISOMERASE
3cvk:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE
4ry6:A (SER478) to (ALA529) C-TERMINAL MUTANT (W550A) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4ry6:B (SER478) to (ARG523) C-TERMINAL MUTANT (W550A) OF HCV/J4 RNA POLYMERASE | HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE
4rzf:A (CYS220) to (LEU265) CRYSTAL STRUCTURE ANALYSIS OF THE NUR77 LIGAND BINDING DOMAIN, S441W MUTANT | TRANSCRIPTION
4s2o:A (GLU129) to (VAL193) OXA-10 IN COMPLEX WITH AVIBACTAM | HYDROLASE-ANTIBIOTIC COMPLEX
4s2o:B (GLU129) to (VAL193) OXA-10 IN COMPLEX WITH AVIBACTAM | HYDROLASE-ANTIBIOTIC COMPLEX
4tnm:A (LEU169) to (GLY203) CRYSTAL STRUCTURE OF ARABIDOPSIS IMPORTIN-ALPHA3 ARMADILLO REPEAT DOMAIN | ARMADILLO REPEAT
3ogw:A (GLU196) to (LEU283) STRUCTURE OF THE COMPLEX OF BOVINE LACTOPEROXIDASE WITH INDOMETHACIN AT 1.9A RESOLUTION | BOVINE LACTOPEROXIDASE, OXIDOREDUCTASE, INDOMETHACIN, IODIDE, MPD, THIOCYANATE ION
4d9n:B (SER315) to (ALA364) CRYSTAL STRUCTURE OF DIAMINOPROPIONATE AMMONIA LYASE FROM ESCHERICHIA COLI IN COMPLEX WITH D-SERINE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4drs:A (PHE370) to (VAL423) CRYSTAL STRUCTURE OF CRYPTOSPORIDIUM PARVUM PYRUVATE KINASE | PYRUVATE, KINASE, GLYCOLYSIS, CRYPTOSPORIDIUM, ALLOSTERIC ENZYME, TRANSFERASE
3pf0:A (ASN235) to (MSE308) CRYSTAL STRUCTURE OF AN IMELYSIN-LIKE PROTEIN (PSYC_1802) FROM PSYCHROBACTER ARCTICUM 273-4 AT 2.15 A RESOLUTION | PUTATIVE METALLOENDOPEPTIDASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
4uox:A (LEU338) to (GLN382) CRYSTAL STRUCTURE OF YGJG IN COMPLEX WITH PYRIDOXAL-5'-PHOSPHATE AND PUTRESCINE | TRANSFERASE, POLYAMINE
4eeh:A (TYR38) to (GLY73) HSP90 ALPHA N-TERMINAL DOMAIN IN COMPLEX WITH AN INHIBITOR 3-(4- HYDROXY-PHENYL)-1H-INDAZOL-6-OL | ATP BINDING, CHAPERONE-CHAPERONE INHIBITOR COMPLEX
4emn:D (GLN313) to (GLY360) CRYSTAL STRUCTURE OF RPFB CATALYTIC DOMAIN IN COMPLEX WITH BENZAMIDINE | ALPHA BETA, HYDROLASE
4uwk:A (ASP388) to (GLY414) DISCOVERY OF (2S)-8-((3R)-3-METHYLMORPHOLIN-4-YL)-1-(3- METHYL-2-OXO-BUTYL)-2-(TRIFLUOROMETHYL)-3,4-DIHYDRO-2H- PYRIMIDO(1,2-A)PYRIMIDIN-6-ONE: A NOVEL POTENT AND SELECTIVE INHIBITOR OF VPS34 FOR THE TREATMENT OF SOLID TUMORS | TRANSFERASE, LIPID KINASE, AUTOPHAGY INHIBITOR
4f9o:A (GLY299) to (GLY360) CRYSTAL STRUCTURE OF RECOMBINANT HUMAN HEXOKINASE TYPE I WITH 2-DEOXY- GLUCOSE 6-PHOSPHATE | HEXOKINASE, 2-DEOXY GLUCOSE-6-PHOSPHATE, TRANSFERASE
4fa7:A (TYR15) to (LEU58) STRUCTURE OF RECOMBINANT CYTOCHROME BA3 OXIDASE MUTANT A204F FROM THERMUS THERMOPHILUS | PROTON PUMP, OXIDOREDUCTASE
4faa:A (PRO16) to (PRO60) STRUCTURE OF RECOMBINANT CYTOCHROME BA3 OXIDASE MUTANT A120F+A204F FROM THERMUS THERMOPHILUS | PROTON PUMP, OXIDOREDUCTASE
4v0j:B (ASN277) to (ARG344) THE CHANNEL-BLOCK SER202GLU, THR104LYS DOUBLE MUTANT OF STEAROYL-ACP-DESATURASE FROM CASTOR BEAN (RICINUS COMMUNIS) | OXIDOREDUCTASE
4v0j:D (ASN277) to (LEU337) THE CHANNEL-BLOCK SER202GLU, THR104LYS DOUBLE MUTANT OF STEAROYL-ACP-DESATURASE FROM CASTOR BEAN (RICINUS COMMUNIS) | OXIDOREDUCTASE
4v0j:F (ASN277) to (GLU338) THE CHANNEL-BLOCK SER202GLU, THR104LYS DOUBLE MUTANT OF STEAROYL-ACP-DESATURASE FROM CASTOR BEAN (RICINUS COMMUNIS) | OXIDOREDUCTASE
3qvn:A (LEU20) to (LEU87) CRYSTAL STRUCTURE OF CYTOSOLIC MNSOD3 FROM CANDIDA ALBICANS | MN SUPEROXIDE DISMUTASE, OXIDOREDUCTASE
4gmc:B (SER478) to (PHE526) CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH A THUMB INHIBITOR | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5kya:A (GLN397) to (TRP457) BRAIN PENETRANT LIVER X RECEPTOR (LXR) MODULATORS BASED ON A 2,4,5,6- TETRAHYDROPYRROLO[3,4-C]PYRAZOLE CORE | NUCLEAR RECEPTOR, LIVER X RECEPTOR, LXRBETA-LBD/RXRBETA-LBD HETERODIMER, CHEMICAL MODULATORS, DNA BINDING PROTEIN
5kya:E (GLN397) to (TRP457) BRAIN PENETRANT LIVER X RECEPTOR (LXR) MODULATORS BASED ON A 2,4,5,6- TETRAHYDROPYRROLO[3,4-C]PYRAZOLE CORE | NUCLEAR RECEPTOR, LIVER X RECEPTOR, LXRBETA-LBD/RXRBETA-LBD HETERODIMER, CHEMICAL MODULATORS, DNA BINDING PROTEIN
5lm2:A (LYS128) to (ALA179) CRYSTAL STRUCTURE OF HD-PTP PHOSPHATASE | COILED COIL, HYDROLASE
5tpm:A (VAL165) to (ALA211) 2.8 ANGSTROM CRYSTAL STRUCTURE OF THE C-TERMINAL DIMERIZATION DOMAIN OF TRANSCRIPTIONAL REGULATOR PDHR FROM ESCHERICHIA COLI. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, HYDROLASE
5tpm:B (VAL165) to (ALA211) 2.8 ANGSTROM CRYSTAL STRUCTURE OF THE C-TERMINAL DIMERIZATION DOMAIN OF TRANSCRIPTIONAL REGULATOR PDHR FROM ESCHERICHIA COLI. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, HYDROLASE
5tpm:D (VAL165) to (ALA211) 2.8 ANGSTROM CRYSTAL STRUCTURE OF THE C-TERMINAL DIMERIZATION DOMAIN OF TRANSCRIPTIONAL REGULATOR PDHR FROM ESCHERICHIA COLI. | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, HYDROLASE
5trj:A (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-{[2-(CARBOXYMETHOXY)BENZENE-1- CARBONYL]AMINO}-3-[(4-CHLOROPHENYL)METHOXY]BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5trj:B (SER478) to (LYS523) CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-{[2-(CARBOXYMETHOXY)BENZENE-1- CARBONYL]AMINO}-3-[(4-CHLOROPHENYL)METHOXY]BENZOIC ACID | NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX