2o95:A (GLN7) to (GLY30) CRYSTAL STRUCTURE OF THE METAL-FREE DIMERIC HUMAN MOV34 MPN DOMAIN (RESIDUES 1-186) | PSMD7, 26S PROTEASOME, MOV34, JAB1/MPN, METAL-FREE DIMER, UNKNOWN FUNCTION
2o95:B (GLN7) to (GLY30) CRYSTAL STRUCTURE OF THE METAL-FREE DIMERIC HUMAN MOV34 MPN DOMAIN (RESIDUES 1-186) | PSMD7, 26S PROTEASOME, MOV34, JAB1/MPN, METAL-FREE DIMER, UNKNOWN FUNCTION
4gsk:B (LYS14) to (ASP31) CRYSTAL STRUCTURE OF AN ATG7-ATG10 CROSSLINKED COMPLEX | UBIQUITIN-LIKE PROTEIN ACTIVATION ENZYME, UBIQUITIN-LIKE PROTEIN TRANSFER ENZYME, PROTEIN TRANSPORT-LIGASE COMPLEX
4wes:B (ALA20) to (LEU33) NITROGENASE MOLYBDENUM-IRON PROTEIN FROM CLOSTRIDIUM PASTEURIANUM AT 1.08 A RESOLUTION | NITROGEN FIXATION, OXIDOREDUCTASE
4wes:D (ALA20) to (LEU33) NITROGENASE MOLYBDENUM-IRON PROTEIN FROM CLOSTRIDIUM PASTEURIANUM AT 1.08 A RESOLUTION | NITROGEN FIXATION, OXIDOREDUCTASE
1a62:A (ASP77) to (PHE89) CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE TRANSCRIPTIONAL TERMINATOR PROTEIN RHO | TRANSCRIPTION TERMINATION, TERMINATION, RNA BINDING DOMAIN, TRANSCRIPTION REGULATION, OB FOLD, F1-ATPASE
3eb3:A (CYS51) to (THR65) VOLTAGE-DEPENDENT K+ CHANNEL BETA SUBUNIT (W121A) IN COMPLEX WITH CORTISONE | KVBETA, CORTISONE, INTERFACE, CYTOPLASM, ION TRANSPORT, IONIC CHANNEL, NADP, PHOSPHOPROTEIN, POTASSIUM, POTASSIUM TRANSPORT, TRANSPORT, VOLTAGE-GATED CHANNEL, TRANSPORT PROTEIN, OXIDOREDUCTASE
1a94:D (ASN83) to (GLY94) STRUCTURAL BASIS FOR SPECIFICITY OF RETROVIRAL PROTEASES | HUMAN IMMUNODEFICIENCY VIRUS PROTEASE, ROUS SARCOMA VIRUS PROTEASE, PROTEIN-MEDIATED INTERACTION, VIRAL MATURATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1a94:E (ASN83) to (GLY94) STRUCTURAL BASIS FOR SPECIFICITY OF RETROVIRAL PROTEASES | HUMAN IMMUNODEFICIENCY VIRUS PROTEASE, ROUS SARCOMA VIRUS PROTEASE, PROTEIN-MEDIATED INTERACTION, VIRAL MATURATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2ohf:A (ASN60) to (HIS78) CRYSTAL STRUCTURE OF HUMAN OLA1 IN COMPLEX WITH AMPPCP | ATPASE; GTPASE; P-LOOP; OBG-LIKE, HYDROLASE
2aoc:B (ASN183) to (GLY194) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT I84V WITH A SUBSTRATE ANALOG P2-NC | HIV-1 PROTEASE, MUTANT, DIMER, SUBSTRATE ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2aod:B (ASN183) to (GLY194) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE WITH A SUBSTRATE ANALOG P2-NC | HIV-1 PROTEASE, MUTANT, DIMER, SUBSTRATE ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2aoe:B (ASN183) to (GLY194) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A SUBSTRATE ANALOG CA-P2 | HIV-1 PROTEASE, SUBSTRATE ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2aog:B (ASN183) to (GLY194) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A SUBSTRATE ANALOG P2-NC | HIV-1 PROTEASE, MUTANT, DIMER, SUBSTRATE ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2aoh:A (ASN83) to (GLY94) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A SUBSTRATE ANALOG P6-PR | HIV-1 PROTEASE, MUTANT, DIMER, SUBSTRATE ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2aoj:B (ASN183) to (GLY194) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE WITH A SUBSTRATE ANALOG P6-PR | HIV-1 PROTEASE, MUTANT, DIMER, SUBSTRATE ANALOG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4wi7:B (GLN342) to (ASN361) STRUCTURAL MAPPING OF THE HUMAN IGG1 BINDING SITE FOR FCRN: HU3S193 FC MUTATION H435A | HUMAN IGG1, FCRN BINDING SITE, THERAPEUTIC ANTIBODY, IMMUNE SYSTEM
4wj3:B (VAL281) to (LEU295) CRYSTAL STRUCTURE OF THE ASPARAGINE TRANSAMIDOSOME FROM PSEUDOMONAS AERUGINOSA | TRANSAMIDOSOME, AMINOACYL-TRNA SYNTHETASE, GATCAB, TRNA, LIGASE-RNA COMPLEX
4wj3:E (VAL281) to (LEU295) CRYSTAL STRUCTURE OF THE ASPARAGINE TRANSAMIDOSOME FROM PSEUDOMONAS AERUGINOSA | TRANSAMIDOSOME, AMINOACYL-TRNA SYNTHETASE, GATCAB, TRNA, LIGASE-RNA COMPLEX
1acm:A (VAL122) to (THR148) ARGININE 54 IN THE ACTIVE SITE OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE IS CRITICAL FOR CATALYSIS: A SITE-SPECIFIC MUTAGENESIS, NMR AND X-RAY CRYSTALLOGRAPHY STUDY | TRANSFERASE (CARBAMOYL-P,ASPARTATE)
3ee6:A (THR550) to (ASN562) CRYSTAL STRUCTURE ANALYSIS OF TRIPEPTIDYL PEPTIDASE -I | TRIPEPETIDYL PEPTIDASE -I, DISEASE MUTATION, EPILEPSY, GLYCOPROTEIN, HYDROLASE, LYSOSOME, NEURONAL CEROID LIPOFUSCINOSIS, PROTEASE, SERINE PROTEASE, ZYMOGEN
2avq:B (ASN83) to (GLY94) KINETICS, STABILITY, AND STRUCTURAL CHANGES IN HIGH RESOLUTION CRYSTAL STRUCTURES OF HIV-1 PROTEASE WITH DRUG RESISTANT MUTATIONS L24I, I50V, AND G73S | HIV-1 PROTEASE, DRUG RESISTANT, SUBSTRATE ANALOG, NON-ACTIVE SITE MUTANTS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2avx:A (GLY91) to (GLY114) SOLUTION STRUCTURE OF E COLI SDIA1-171 | HOMOSERINE LACTONE, QUORUM SENSING, TRANSCRIPTION
1nlu:A (GLY354) to (SER367) PSEUDOMONAS SEDOLISIN (SERINE-CARBOXYL PROTEINASE) COMPLEXED WITH TWO MOLECULES OF PSEUDO-IODOTYROSTATIN | PSCP, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ajv:A (ASN83) to (GLY94) HIV-1 PROTEASE IN COMPLEX WITH THE CYCLIC SULFAMIDE INHIBITOR AHA006 | PROTEASE, ASPARTYL PROTEASE, NON-PEPTIDE INHIBITOR, DRUG DESIGN, HIV-1
1ajv:B (ASN83) to (GLY94) HIV-1 PROTEASE IN COMPLEX WITH THE CYCLIC SULFAMIDE INHIBITOR AHA006 | PROTEASE, ASPARTYL PROTEASE, NON-PEPTIDE INHIBITOR, DRUG DESIGN, HIV-1
1ajx:B (ASN83) to (GLY94) HIV-1 PROTEASE IN COMPLEX WITH THE CYCLIC UREA INHIBITOR AHA001 | PROTEASE, ASPARTYL PROTEASE, NON-PEPTIDE INHIBITOR, DRUG DESIGN, HIV-1
4wna:B (ALA148) to (GLY159) STRUCTURE OF THE NITROGENASE MOFE PROTEIN FROM AZOTOBACTER VINELANDII PRESSURIZED WITH XENON | XENON, MOFE PROTEIN, NITROGENASE, SUBSTRATE ACCESS, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
1npa:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE-HUP | PROTEASE, HIV, ASPARTYL PROTEASE, HYDROLASE
1npa:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE-HUP | PROTEASE, HIV, ASPARTYL PROTEASE, HYDROLASE
1npw:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH LGZ479 | PROTEASE, HYDROLASE
1npw:B (ASN283) to (GLY294) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH LGZ479 | PROTEASE, HYDROLASE
3ej8:A (VAL431) to (SER453) STRUCTURE OF DOUBLE MUTANT OF HUMAN INOS OXYGENASE DOMAIN WITH BOUND IMMIDAZOLE | NITRIC OXIDE SYNTHASE, NOS, HEME, TETRAHYDROBIOPTERIN, OXIDOREDUCTASE CALMODULIN-BINDING, FAD, FMN, IRON, METAL- BINDING, NADP, OXIDOREDUCTASE, POLYMORPHISM, ZINC
3ej8:C (VAL431) to (GLY455) STRUCTURE OF DOUBLE MUTANT OF HUMAN INOS OXYGENASE DOMAIN WITH BOUND IMMIDAZOLE | NITRIC OXIDE SYNTHASE, NOS, HEME, TETRAHYDROBIOPTERIN, OXIDOREDUCTASE CALMODULIN-BINDING, FAD, FMN, IRON, METAL- BINDING, NADP, OXIDOREDUCTASE, POLYMORPHISM, ZINC
3rzz:A (THR72) to (SER84) STRUCTURE OF HYDROXYETHYLPHOSHPHONATE DIOXYGENASE Y98F MUTANT | NON HEME FE(II) DIOXYGENASE, CUPIN, BIOSYNTHETIC PROTEIN, OXIDOREDUCTASE
3ekq:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF INHIBITOR SAQUINAVIR (SQV) IN COMPLEX WITH MULTI- DRUG RESISTANT HIV-1 PROTEASE (L63P/V82T/I84V) (REFERRED TO AS ACT IN PAPER) | PROTEASE INHIBITOR, DRUG RESISTANCE, ENTROPY ENTHALPY COMPENSATION, AIDS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASE
3ekw:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF THE INHIBITOR ATAZANAVIR (ATV) IN COMPLEX WITH A MULTI-DRUG RESISTANCE HIV-1 PROTEASE VARIANT (L10I/G48V/I54V/V64I/V82A) REFER: FLAP+ IN CITATION. | HIV-1, PROTEASE, MULTI-DRUG RESISTANCE, ATAZANAVIR, AIDS, HYDROLASE
2b5l:B (TYR245) to (GLN255) CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH SIMIAN VIRUS 5 V PROTEIN | DDB1, SV5-V, BETA PROPELLER, PROPELLER CLUSTER, ZINC FINGER, PROTEIN BINDING/VIRAL PROTEIN COMPLEX
3eky:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD-TYPE HIV PROTEASE IN COMPLEX WITH THE INHIBITOR, ATAZANAVIR | HIV PROTEASE, PROTEASE INHIBITORS, DRUG RESISTANCE, ATAZANAVIR, AIDS, HYDROLASE, PROTEASE
3elf:A (ASP47) to (SER61) STRUCTURAL CHARACTERIZATION OF TETRAMERIC MYCOBACTERIUM TUBERCULOSIS FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE - SUBSTRATE BINDING AND CATALYSIS MECHANISM OF A CLASS IIA BACTERIAL ALDOLASE | CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE, ZINC ENZYME, MYCOBACTERIUM TUBERCULOSIS, DIHYDROXYACETONE, GLYCERALDEHYDE-3- PHOSPHATE, ALDOL CONDENSATION, GLYCOLYSIS, LYASE, METAL-BINDING, ZINC
3em3:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF AMPRENAVIR (APV) IN COMPLEX WITH A DRUG RESISTANT HIV-1 PROTEASE VARIANT (I50L/A71V). | PROTEASE INHIBITOR, HYPER SUSCEPTIBILITY, DRUG RESISTANCE, HIV, AMPRENAVIR, AIDS, HYDROLASE, PROTEASE
3em4:V (ASN83) to (GLY94) CRYSTAL STRUCTURE OF ATAZANAVIR (ATV) IN COMPLEX WITH I50L/A71V DRUG- RESISTANT HIV-1 PROTEASE | DRUG RESISTANCE, HYPERSUSCEPTIBILITY, PROTEASE INHIBITOR, HIV, ATAZANAVIR, AIDS, HYDROLASE, PROTEASE
3em6:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF I50L/A71V MUTANT OF HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR DARUNAVIR | PROTEASE INHIBITOR, HYPER SUSCEPTIBILITY, DRUG RESISTANCE, HIV, DARUNAVIR, AIDS, HYDROLASE, PROTEASE
2ox4:B (HIS217) to (ILE230) CRYSTAL STRUCTURE OF PUTATIVE DEHYDRATASE FROM ZYMOMONAS MOBILIS ZM4 | ENOLASE, DEHYDRATASE, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NYSGRC, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, ISOMERASE
2ox4:C (HIS217) to (ILE230) CRYSTAL STRUCTURE OF PUTATIVE DEHYDRATASE FROM ZYMOMONAS MOBILIS ZM4 | ENOLASE, DEHYDRATASE, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, NYSGRC, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, ISOMERASE
1axa:A (ASN83) to (GLY94) ACTIVE-SITE MOBILITY IN HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE AS DEMONSTRATED BY CRYSTAL STRUCTURE OF A28S MUTANT | HIV PROTEASE, MUTANT, X-RAY, ASPARTIC PROTEASE, HYDROLASE, ACID PROTEINASE, ASPARTYL PROTEASE
2b7q:B (ALA154) to (VAL165) CRYSTAL STRUCTURE OF QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE FROM HELICOBACTER PYLORI | QUINOLINATE PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, HELICOBACTER PYLORI, TRANSFERASE
4hab:C (PHE559) to (SER593) CRYSTAL STRUCTURE OF PLK1 POLO-BOX DOMAIN IN COMPLEX WITH PL-49 | POLO-BOX DOMAIN, PHOSPHOPROTEIN-BINDING DOMAIN, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3s1n:A (TRP1191) to (LYS1205) RNA POLYMERASE II INITIATION COMPLEX WITH A 5-NT RNA (VARIANT 2) | RNA POLYMERASE II, INITIATION COMPLEX, TRANSCRIPTION-RNA-DNA COMPLEX
1b16:A (ARG38) to (ASN52) ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS TERNARY COMPLEX WITH NAD-3-PENTANONE | OXIDOREDUCTASE, DETOXIFICATION, METABOLISM, ALCOHOL DEHYDROGENASE, DROSOPHILA LEBANONENSIS, SHORT-CHAIN DEHYDROGENASES/REDUCTASES, TERNARY COMPLEX, NAD-3- PENTANONE ADDUCT
1nzc:B (TRP35) to (GLY49) THE HIGH RESOLUTION STRUCTURES OF RMLC FROM STREPTOCOCCUS SUIS IN COMPLEX WITH DTDP-D-XYLOSE | JELLY ROLL-LIKE STRUCTURE; BETA SHEET, ISOMERASE
2p38:A (LEU5) to (GLY26) CRYSTAL STRUCTURE OF PYROCOCCUS ABYSSI PROTEIN HOMOLOGUE OF SACCHAROMYCES CEREVISIAE NIP7P | TWO ALPHA/BETA DOMAINS, PUA DOMAIN, BIOSYNTHETIC PROTEIN
2p38:B (LEU5) to (GLY26) CRYSTAL STRUCTURE OF PYROCOCCUS ABYSSI PROTEIN HOMOLOGUE OF SACCHAROMYCES CEREVISIAE NIP7P | TWO ALPHA/BETA DOMAINS, PUA DOMAIN, BIOSYNTHETIC PROTEIN
3es9:A (HIS601) to (ASP612) NADPH-CYTOCHROME P450 REDUCTASE IN AN OPEN CONFORMATION | CYTOCHROME P450 REDUCTASE, OXIDOREDUCTASE, OPEN CONFORMATION, ACETYLATION, ENDOPLASMIC RETICULUM, FAD, FLAVOPROTEIN, FMN, MEMBRANE, NADP, PHOSPHOPROTEIN
3et0:A (GLN345) to (LEU356) STRUCTURE OF PPARGAMMA WITH 3-(5-METHOXY-1H-INDOL-3-YL)- PROPIONIC ACID | PPAR, PPARG, PPARGAMMA, DRUG DISCOVERY, DIABETES, ADIPONECTIN, METABOLIC DISEASE, FRAGMENT-BASED DRUG DISCOVERY, SCAFFOLD-BASED DRUG DISCOVERY, ACTIVATOR, ALTERNATIVE SPLICING, DIABETES MELLITUS, DISEASE MUTATION, DNA-BINDING, METAL-BINDING, NUCLEUS, OBESITY, PHOSPHOPROTEIN, POLYMORPHISM, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC, ZINC-FINGER
1b4u:B (ASN121) to (GLY138) PROTOCATECHUATE 4,5-DIOXYGENASE (LIGAB) IN COMPLEX WITH PROTOCATECHUATE (PCA) | EXTRADIOL TYPE DIOXYGENASE, PROTOCATECHUATE, NON-HEME IRON PROTEIN
1b4u:D (ASN121) to (GLY138) PROTOCATECHUATE 4,5-DIOXYGENASE (LIGAB) IN COMPLEX WITH PROTOCATECHUATE (PCA) | EXTRADIOL TYPE DIOXYGENASE, PROTOCATECHUATE, NON-HEME IRON PROTEIN
1b6k:A (ASN83) to (GLY94) HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 5 | COMPLEX (ACID PROTEINASE/PEPTIDE), HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1b6j:A (ASN83) to (GLY94) HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 1 | COMPLEX (ACID PROTEINASE-PEPTIDE), HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1b6m:A (ASN83) to (GLY94) HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 6 | COMPLEX (ACID PROTEINASE-PEPTIDE), HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1b6p:A (ASN83) to (GLY94) HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 7 | COMPLEX (ACID PROTEINASE/PEPTIDE), HYDROLASE/HYDROLASE INHIBITOR COMPLEX
3etu:A (VAL152) to (PRO169) CRYSTAL STRUCTURE OF YEAST DSL1P | HELICAL BUNDLE, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, MEMBRANE, PHOSPHOPROTEIN, PROTEIN TRANSPORT, TRANSPORT, TRANSPORT PROTEIN
3etv:A (VAL164) to (PHE180) CRYSTAL STRUCTURE OF A TIP20P-DSL1P FUSION PROTEIN | TIP20P-DSL1P COMPLEX, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, MEMBRANE, PHOSPHOPROTEIN, PROTEIN TRANSPORT, TRANSPORT, TRANSPORT PROTEIN
2be9:A (ILE117) to (PHE144) CRYSTAL STRUCTURE OF THE CTP-LIGANDED (T-STATE) ASPARTATE TRANSCARBAMOYLASE FROM THE EXTREMELY THERMOPHILIC ARCHAEON SULFOLOBUS ACIDOCALDARIUS | ATCASE, HYPERTHERMOPHILIC, TEMPERATURE, TRANSFERASE,ALLOSTERIC, HOLOENZYME, CTP COMPLEX, TRANSFERASE
4wzn:B (ASN958) to (GLY970) CRYSTAL STRUCTURE OF THE 2B PROTEIN SOLUBLE DOMAIN FROM HEPATITIS A VIRUS | FIBER, VIRAL RECRUITMENT MACHINERY, VIRAL PROTEIN, HEPATITIS A VIRUS, NON-STRUCTURAL PROTEIN
2bil:B (PRO125) to (ARG136) THE HUMAN PROTEIN KINASE PIM1 IN COMPLEX WITH ITS CONSENSUS PEPTIDE PIMTIDE | PIM1, KINASE, CANCER, LEUKEMIA, TRANSFERASE
3s43:B (ASN183) to (GLY194) HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH ANTIVIRAL DRUG AMPRENAVIR | AMPRENAVIR, HIV/AIDS, DRUG RESISTANCE, ASPARTIC PROTEASE, MOLECULAR RECOGNITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2pc8:A (ASN247) to (ARG265) E292Q MUTANT OF EXO-B-(1,3)-GLUCANASE FROM CANDIDA ALBICANS IN COMPLEX WITH TWO SEPARATELY BOUND GLUCOPYRANOSIDE UNITS AT 1.8 A | EXO-GLUCANASE, CANDIDA ALBICANS, CARBOHYDRATE BINDING, ADDITIONAL CH BINDING SITE, HYDROLASE
3f1t:C (GLY52) to (VAL74) CRYSTAL STRUCTURE OF THE Q9I3C8_PSEAE PROTEIN FROM PSEUDOMONAS AERUGINOSA. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET PAR319A. | Q9I3C8_PSEAE, PAR319A, NESG, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, UNKNOWN FUNCTION
2pe3:C (GLU326) to (GLU346) CRYSTAL STRUCTURE OF FRV OPERON PROTEIN FRVX (PH1821)FROM PYROCOCCUS HORIKOSHII OT3 | AMINOPEPTIDASE, SELF-COMPARTMENTALIZING, METALLOPROTEASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, HYDROLASE
4hn0:A (TRP27) to (ALA36) CRYSTAL STRUCTURE OF CHMJ, A 3'-MONOEPIMERASE APOENZYME FROM STREPTOMYCES BIKINIENSIS | 3'-MONOEPIMERASE, NATURAL PRODUCT, DEOXYSUGAR, CHALCOMYCIN, DTDP- MYCINOSE, CUPIN FOLD, NUCLEOTIDE-LINKED SUGAR, EPIMERIZATION, UNKNOWN FUNCTION
4hn0:B (TRP27) to (ALA36) CRYSTAL STRUCTURE OF CHMJ, A 3'-MONOEPIMERASE APOENZYME FROM STREPTOMYCES BIKINIENSIS | 3'-MONOEPIMERASE, NATURAL PRODUCT, DEOXYSUGAR, CHALCOMYCIN, DTDP- MYCINOSE, CUPIN FOLD, NUCLEOTIDE-LINKED SUGAR, EPIMERIZATION, UNKNOWN FUNCTION
4hn0:D (TRP27) to (ALA36) CRYSTAL STRUCTURE OF CHMJ, A 3'-MONOEPIMERASE APOENZYME FROM STREPTOMYCES BIKINIENSIS | 3'-MONOEPIMERASE, NATURAL PRODUCT, DEOXYSUGAR, CHALCOMYCIN, DTDP- MYCINOSE, CUPIN FOLD, NUCLEOTIDE-LINKED SUGAR, EPIMERIZATION, UNKNOWN FUNCTION
2pf0:A (ASN247) to (ARG265) F258I MUTANT OF EXO-B-(1,3)-GLUCANASE FROM CANDIDA ALBICANS AT 1.9 A | EXO-GLUCANASE, CANDIDA ALBICANS, CARBOHYDRATE BINDING, AROMATIC ENTRANCEWAY, HYDROLASE
1o4u:B (CYS153) to (GLY165) CRYSTAL STRUCTURE OF A NICOTINATE NUCLEOTIDE PYROPHOSPHORYLASE (TM1645) FROM THERMOTOGA MARITIMA AT 2.50 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI, TRANSFERASE
2bmu:B (ILE3) to (VAL13) UMP KINASE FROM PYROCOCCUS FURIOSUS COMPLEXED WITH ITS SUBSTRATE UMP AND ITS SUBSTRATE ANALOG AMPPNP | UMP KINASE, AMINO ACID KINASE, PHOSPHORYL GROUP TRANSFER, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
4x55:B (ASN72) to (GLN93) STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-225 K82D IN ACYL-ENZYME COMPLEX WITH CEFTAZIDIME | HYDROLASE, CARBAPENEMASE, ANTIBIOTIC
3s54:B (ASN83) to (GLY94) HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH ANTIVIRAL DRUG DARUNAVIR IN SPACE GROUP P21212 | DARUNAVIR,HIV/AIDS, DRUG RESISTANCE, ASPARTIC PROTEASE, MOLECULAR RECOGNITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2bof:X (GLY236) to (ALA286) CATALYTIC DOMAIN OF ENDO-1,4-GLUCANASE CEL6A MUTANT Y73S FROM THERMOBIFIDA FUSCA IN COMPLEX WITH CELLOTETROSE | HYDROLASE, ENDOGLUCANASE, THERMOBIFIDA FUSCA, TIM A/B FOLD, GLYCOSIDE HYDROLASE FAMILY 6, METHYL CELLOBIOSYL-4-THIO-BETA- CELLOBIOSIDE
1bp1:A (GLY4) to (ILE32) CRYSTAL STRUCTURE OF BPI, THE HUMAN BACTERICIDAL PERMEABILITY-INCREASING PROTEIN | BACTERICIDAL, PERMEABILITY-INCREASING, LIPID-BINDING, LIPOPOLYSACCHARIDE-BINDING, ANTIBIOTIC
2bpv:B (ASN83) to (GLY94) HIV-1 PROTEASE-INHIBITOR COMPLEX | ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2bpw:B (ASN83) to (GLY94) HIV-1 PROTEASE-INHIBITOR COMPLEX | ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2bpy:B (ASN83) to (GLY94) HIV-1 PROTEASE-INHIBITOR COMPLEX | ACID PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2bpz:B (ASN83) to (GLY94) HIV-1 PROTEASE-INHIBITOR COMPLEX | ACID PROTEASE, HYDROLASE-HYDROLASE COMPLEX
2bri:A (ILE3) to (VAL13) UMP KINASE FROM PYROCOCCUS FURIOSUS COMPLEXED WITH ITS SUBSTRATE ANALOG AMPPNP | UMP KINASE, AMINO ACID KINASE, PHOSPHORYL GROUP TRANSFER, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
1o90:A (PHE19) to (ASP50) METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH A L-METHIONINE ANALOGOUS | ADENOSYLTRANSFERASE, METHIONINE BINDING, TRANSFERASE
1o90:B (PHE19) to (ASP50) METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH A L-METHIONINE ANALOGOUS | ADENOSYLTRANSFERASE, METHIONINE BINDING, TRANSFERASE
1o92:A (PHE19) to (ASP50) METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH ADP AND A L-METHIONINE ANALOGOUS | TRANSFERASE, ADENOSYLTRANSFERASE, METHIONINE BINDING, ADP BINDING
1o92:B (PHE19) to (ASP50) METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH ADP AND A L-METHIONINE ANALOGOUS | TRANSFERASE, ADENOSYLTRANSFERASE, METHIONINE BINDING, ADP BINDING
3s85:F (ASN83) to (GLY94) DISCOVERY OF NEW HIV PROTEASE INHIBITORS WITH POTENTIAL FOR CONVENIENT DOSING AND REDUCED SIDE EFFECTS: A-790742 AND A-792611. | BETA BARREL, ACID PROTEASE, ASPARTIC-TYPE ENDOPEPIDASE ACTIVITY, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2brx:A (ILE3) to (VAL13) UMP KINASE FROM PYROCOCCUS FURIOSUS WITHOUT LIGANDS | UMP KINASE, AMINO ACID KINASE, PHOSPHORYL GROUP TRANSFER, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
2brx:B (ILE3) to (VAL13) UMP KINASE FROM PYROCOCCUS FURIOSUS WITHOUT LIGANDS | UMP KINASE, AMINO ACID KINASE, PHOSPHORYL GROUP TRANSFER, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
2bsq:A (MET1) to (ARG14) FITAB BOUND TO DNA | TRANSCRIPTION, TRANSCRIPTION REGULATION COMPLEX, PIN DOMAIN, RIBBON-HELIX-HELIX, DNA BINDING, HETERODIMER
1o9t:A (PHE19) to (ASP50) METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH BOTH SUBSTRATES ATP AND METHIONINE | TRANSFERASE, ADENOSYLTRANSFERASE, ATP BINDING, METHIONINE BINDING, ONE-CARBON METABOLISM, MAGNESIUM, POTASSIUM, METAL-BINDING, MULTIGENE FAMILY, ATP-BINDING
1o9t:B (PHE19) to (ASP50) METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH BOTH SUBSTRATES ATP AND METHIONINE | TRANSFERASE, ADENOSYLTRANSFERASE, ATP BINDING, METHIONINE BINDING, ONE-CARBON METABOLISM, MAGNESIUM, POTASSIUM, METAL-BINDING, MULTIGENE FAMILY, ATP-BINDING
4x8i:A (GLU318) to (LEU339) DE NOVO CRYSTAL STRUCTURE OF THE PYROCOCCUS FURIOSUS TET3 AMINOPEPTIDASE | AMINOPEPTIDASE, HYDROLASE
4x8i:B (GLU318) to (LEU339) DE NOVO CRYSTAL STRUCTURE OF THE PYROCOCCUS FURIOSUS TET3 AMINOPEPTIDASE | AMINOPEPTIDASE, HYDROLASE
4x8i:C (GLU318) to (GLU337) DE NOVO CRYSTAL STRUCTURE OF THE PYROCOCCUS FURIOSUS TET3 AMINOPEPTIDASE | AMINOPEPTIDASE, HYDROLASE
3fa3:C (ASP41) to (GLY56) CRYSTAL STRUCTURE OF 2,3-DIMETHYLMALATE LYASE, A PEP MUTASE/ISOCITRATE LYASE SUPERFAMILY MEMBER, TRIGONAL CRYSTAL FORM | ALPHA/BETA BARREL, HELIX SWAPPING, LYASE
2bu3:A (ASN32) to (SER48) ACYL-ENZYME INTERMEDIATE BETWEEN ALR0975 AND GLUTATHIONE AT PH 3.4 | PHYTOCHELATIN SYNTHASE, PCS, ALR0975, ACYL-ENZYME INTERMEDIATE, NOSTOC, GLUTATHIONE METABOLISM, CYSTEINE PROTEASE, TRANSFERASE
1ob8:B (ASN59) to (MET77) HOLLIDAY JUNCTION RESOLVING ENZYME | HYDROLASE, ENZYME, HOMOLOGOUS RECOMBINATION, HOLLIDAY JUNCTION RESOLVING ENZYME, NUCLEASE, ARCHAEA, THERMOPHILE
1ob9:A (ASN59) to (MET77) HOLLIDAY JUNCTION RESOLVING ENZYME | HYDROLASE, ENZYME, HOMOLOGOUS RECOMBINATION, HOLLIDAY JUNCTION RESOLVING ENZYME, NUCLEASE, ARCHAEA, THERMOPHILE
3sa4:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF72 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3sa5:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF69 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3saa:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH AF77 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1obc:A (GLU124) to (GLY147) LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A POST-TRANSFER EDITING SUBSTRATE ANALOGUE | AMINOACYL-TRNA SYNTHETASE, CLASS I AMINOACYL-TRNA SYNTHETASE, ATP + L-LEUCINE + TRNA (LEU) -> AMP + PPI L- LEUCYL-TRNA(LEU), SYNTHETASE
1obp:A (LEU122) to (GLY140) ODORANT-BINDING PROTEIN FROM BOVINE NASAL MUCOSA | OLFACTION, NOSE, TRANSPORT, LIPOCALIN, ODORANT-BINDING PROTEIN
2pg2:A (GLN20) to (SER36) CRYSTAL STRUCTURE OF KSP IN COMPLEX WITH ADP AND THIOPHENE CONTAINING INHIBITOR 15 | KINESIN SPINDLE PROTEIN; KSP; EG5; COMPLEX; INHIBITOR; THIOPHENE, MOTOR PROTEIN,CELL CYCLE
2pg2:B (GLN20) to (SER36) CRYSTAL STRUCTURE OF KSP IN COMPLEX WITH ADP AND THIOPHENE CONTAINING INHIBITOR 15 | KINESIN SPINDLE PROTEIN; KSP; EG5; COMPLEX; INHIBITOR; THIOPHENE, MOTOR PROTEIN,CELL CYCLE
4hu4:B (THR715) to (CYS727) CRYSTAL STRUCTURE OF EAL DOMAIN OF THE E. COLI DOSP - DIMERIC FORM | EAL DOMAIN; CYCLIC DI-GMP PHOSPHODIESTERASE; TIM-BARREL; ECDOS; DIRECT OXYGEN SENSOR, SIGNALING PROTEIN,HYDROLASE
1odx:A (ASN83) to (GLY94) HIV-1 PROTEINASE MUTANT A71T, V82A | PROTEINASE, RETROPEPSIN, RETROVIRUS, HIV, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3fdz:A (TYR2) to (ASN18) CRYSTAL STRUCTURE OF PHOSPHOGLYCEROMUTASE FROM BURKHOLDERIA PSEUDOMALLEI 1710B WITH BOUND 2,3-DIPHOSPHOGLYCERIC ACID AND 3- PHOSPHOGLYCERIC ACID | ISOMERASE, SSGCID, PHOSPHOGLYCEROMUTASE, BURKHOLDERIA PSEUDOMALLEI, GLYCOLYSIS, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3fdz:B (MET1) to (ASN18) CRYSTAL STRUCTURE OF PHOSPHOGLYCEROMUTASE FROM BURKHOLDERIA PSEUDOMALLEI 1710B WITH BOUND 2,3-DIPHOSPHOGLYCERIC ACID AND 3- PHOSPHOGLYCERIC ACID | ISOMERASE, SSGCID, PHOSPHOGLYCEROMUTASE, BURKHOLDERIA PSEUDOMALLEI, GLYCOLYSIS, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
4hw6:B (TRP174) to (SER182) CRYSTAL STRUCTURE OF AN AUXILIARY NUTRIENT BINDING PROTEIN (BACOVA_00264) FROM BACTEROIDES OVATUS ATCC 8483 AT 1.70 A RESOLUTION | PUTATIVE CARBOHYDRATE BINDNING TWO DOMAINS PROTEIN, IPT/TIG DOMAIN (PF01833), 6-BETA-PROPELLER, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, UNKNOWN FUNCTION
2pk5:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, L33I, L63I ) IN COMPLEX WITH KNI-10075 | PROTEASE COMPLEX, VIRAL PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2pk6:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, L33I, L63I) IN COMPLEX WITH KNI-10033 | PROTEASE COMPLEX, VIRAL PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2pk6:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, L33I, L63I) IN COMPLEX WITH KNI-10033 | PROTEASE COMPLEX, VIRAL PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2pmf:A (LEU319) to (GLY330) THE CRYSTAL STRUCTURE OF A HUMAN GLYCYL-TRNA SYNTHETASE MUTANT | CLASSIIA AMINOACYL-TRNA SYNTHETASE, LIGASE
2bzj:A (PRO125) to (GLU135) CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU3 | PIM1, KINASE, CANCER, LEUKEMIA, NUCLEAR PROTEIN, NUCLEOTIDE- BINDING, TRANSFERASE
2bzk:B (PRO125) to (GLU135) CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH AMPPNP AND PIMTIDE | TRANSFERASE-PEPTIDE COMPLEX, COMPLEX TRANSFERASE/PEPTIDE, PIM1, KINASE, CANCER, LEUKEMIA, ATP-BINDING, NUCLEAR PROTEIN, NUCLEOTIDE-BINDING, PHOSPHORYLATION, PROTO- ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
4xgq:E (MET0) to (LEU12) CRYSTAL STRUCTURE OF ADDICTION MODULE FROM MYCOBACTERIAL SPECIES | MYCOBACTERIA, ADDICTION MODULE, TOXIN-ANTITOXIN COMPLEX
3fhh:A (MET21) to (ALA35) CRYSTAL STRUCTURE OF THE HEME/HEMOGLOBIN OUTER MEMBRANE TRANSPORTER SHUA FROM SHIGELLA DYSENTERIAE | MEMBRANE PROTEIN, TRANSPORTER, TONB-DEPENDENT TRANSPORTER, MEMBRANE, RECEPTOR, TONB BOX
3sg1:A (ILE82) to (MET92) 2.6 ANGSTROM CRYSTAL STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE 1- CARBOXYVINYLTRANSFERASE 1 (MURA1) FROM BACILLUS ANTHRACIS | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, CELL WALL FORMATION, TRANSFERASE
3sg1:B (ILE82) to (MET92) 2.6 ANGSTROM CRYSTAL STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE 1- CARBOXYVINYLTRANSFERASE 1 (MURA1) FROM BACILLUS ANTHRACIS | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, CELL WALL FORMATION, TRANSFERASE
3sg1:D (ILE82) to (MET92) 2.6 ANGSTROM CRYSTAL STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE 1- CARBOXYVINYLTRANSFERASE 1 (MURA1) FROM BACILLUS ANTHRACIS | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, CELL WALL FORMATION, TRANSFERASE
4xhn:A (ASN194) to (PHE211) BACILLUS THURINGIENSIS PARM WITH AMPPNP | STRUCTURAL PROTEIN, BACTERIAL ACTIN-LIKE PROTEIN, BACTERIAL CYTOSKELETON
1ohr:A (ASN83) to (GLY94) VIRACEPT (R) (NELFINAVIR MESYLATE, AG1343): A POTENT ORALLY BIOAVAILABLE INHIBITOR OF HIV-1 PROTEASE | ASPARTYL PROTEASE, HYDROLASE, HIV-I PROTEASE
1oi0:A (MET4) to (ALA21) CRYSTAL STRUCTURE OF AF2198, A JAB1/MPN DOMAIN PROTEIN FROM ARCHAEOGLOBUS FULGIDUS | PROTEASOME, DEUBIQUITINATION, ARCHAEA, HYDROLASE
1oi0:D (MET4) to (ALA21) CRYSTAL STRUCTURE OF AF2198, A JAB1/MPN DOMAIN PROTEIN FROM ARCHAEOGLOBUS FULGIDUS | PROTEASOME, DEUBIQUITINATION, ARCHAEA, HYDROLASE
3shf:A (ASP392) to (TRP404) CRYSTAL STRUCTURE OF THE R265S MUTANT OF FULL-LENGTH MURINE APAF-1 | TANDEM BETA-PROPELLER, APOPTOSIS, CYTOCHROME C, ADENINE NUCLEOTIDE, PROCASPASE-9, CYTOSOL
3fjo:A (HIS581) to (ARG593) STRUCTURE OF CHIMERIC YH CPR | FMN AND FAD DOMAINS OF CPR, OXIDOREDUCTASE, ENDOPLASMIC RETICULUM, FLAVOPROTEIN, MEMBRANE, NADP, PHOSPHOPROTEIN, TRANSMEMBRANE, CONGENITAL ADRENAL HYPERPLASIA, DISEASE MUTATION
3si2:A (LEU244) to (GLY283) STRUCTURE OF GLYCOSYLATED MURINE GLUTAMINYL CYCLASE IN PRESENCE OF THE INHIBITOR PQ50 (PDBD150) | ALPHA/BETA HYDROLASE, ALZHEIMER'S DISEASE, PYROGLUTAMATE, PGLU, PE, PGLU-AMYLOID, GLYCOSYLATION, GLYCOPROTEIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4xjy:D (VAL174) to (ALA184) PERIPLASMIC REPRESSOR PROTEIN YFIR | INHIBITOR, PERIPLASM, SIGNAL TRANSDUCTION, SIGNALING PROTEIN
3fmw:A (ALA53) to (GLY68) THE CRYSTAL STRUCTURE OF MTMOIV, A BAEYER-VILLIGER MONOOXYGENASE FROM THE MITHRAMYCIN BIOSYNTHETIC PATHWAY IN STREPTOMYCES ARGILLACEUS. | OXYGENASE, MITHRAMYCIN, BAEYER-VILLIGER, FLAVIN BINDING PROTEIN, OXIDOREDUCTASE
3fmw:B (ALA53) to (GLY68) THE CRYSTAL STRUCTURE OF MTMOIV, A BAEYER-VILLIGER MONOOXYGENASE FROM THE MITHRAMYCIN BIOSYNTHETIC PATHWAY IN STREPTOMYCES ARGILLACEUS. | OXYGENASE, MITHRAMYCIN, BAEYER-VILLIGER, FLAVIN BINDING PROTEIN, OXIDOREDUCTASE
3fmw:C (ALA53) to (GLY68) THE CRYSTAL STRUCTURE OF MTMOIV, A BAEYER-VILLIGER MONOOXYGENASE FROM THE MITHRAMYCIN BIOSYNTHETIC PATHWAY IN STREPTOMYCES ARGILLACEUS. | OXYGENASE, MITHRAMYCIN, BAEYER-VILLIGER, FLAVIN BINDING PROTEIN, OXIDOREDUCTASE
2pwc:B (ASN83) to (GLY94) HIV-1 PROTEASE IN COMPLEX WITH A AMINO DECORATED PYRROLIDINE-BASED INHIBITOR | PROTEIN-LIGAND COMPLEX, HYDROLASE
3fns:A (GLY119) to (ASN144) CRYSTAL STRUCTURE OF HISTO-ASPARTIC PROTEASE (HAP) FROM PLASMODIUM FALCIPARUM | HISTO-ASPARTIC PROTEASE, HAP, PLASMEPSIN, ASPARTIC PROTEASE, HORMONE, HYDROLASE
4i92:A (ARG42) to (THR53) STRUCTURE OF THE BSK8 KINASE DOMAIN | PROTEIN KINASE, PSEUDO KINASE, CFG, ALANINE GATEKEEPER, TRANSFERASE BRASSINOSTEROID-SIGNALING, TRANSFERASE
4i93:A (ARG42) to (THR53) STRUCTURE OF THE BSK8 KINASE DOMAIN (SEMET LABELED) | PROTEIN KINASE, PSEUDO KINASE, CFG, ALANINE GATEKEEPER, TRANSFERASE BRASSINOSTEROID-SIGNALING, SEMET DERIVATIVE, TRANSFERASE
4i93:B (PHE41) to (THR53) STRUCTURE OF THE BSK8 KINASE DOMAIN (SEMET LABELED) | PROTEIN KINASE, PSEUDO KINASE, CFG, ALANINE GATEKEEPER, TRANSFERASE BRASSINOSTEROID-SIGNALING, SEMET DERIVATIVE, TRANSFERASE
4i94:A (ARG42) to (THR53) STRUCTURE OF BSK8 IN COMPLEX WITH AMP-PNP | PROTEIN KINASE, PSEUDO KINASE, CFG, ALANINE GATEKEEPER, TRANSFERASE, BRASSINOSTEROID-SIGNALING, AMP-PNP, MG2+
4i94:B (ARG42) to (THR53) STRUCTURE OF BSK8 IN COMPLEX WITH AMP-PNP | PROTEIN KINASE, PSEUDO KINASE, CFG, ALANINE GATEKEEPER, TRANSFERASE, BRASSINOSTEROID-SIGNALING, AMP-PNP, MG2+
1cpi:A (ASN83) to (GLY94) REGIOSELECTIVE STRUCTURAL AND FUNCTIONAL MIMICRY OF PEPTIDES. DESIGN OF HYDROLYTICALLY STABLE CYCLIC PEPTIDOMIMETIC INHIBITORS OF HIV-1 PROTEASE | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3fsu:A (ASN278) to (GLY291) CRYSTAL STRUCTURE OF ESCHERICHIA COLI METHYLENETETRAHYDROFOLATE REDUCTASE DOUBLE MUTANT PHE223LEUGLU28GLN COMPLEXED WITH METHYLTETRAHYDROFOLATE | TIM BARREL, FLAVIN, REDUCTASE, METHYLTETRAHYDROFOLATE, AMINO-ACID BIOSYNTHESIS, FAD, FLAVOPROTEIN, METHIONINE BIOSYNTHESIS, NAD, NADP, OXIDOREDUCTASE
2q2z:B (ILE19) to (SER36) CRYSTAL STRUCTURE OF KSP IN COMPLEX WITH INHIBITOR 22 | KSP, KSP-INHIBITOR COMPLEX, CELL CYCLE
2q4l:B (SER185) to (GLU212) ENSEMBLE REFINEMENT OF THE CRYSTAL STRUCTURE OF GALT-LIKE PROTEIN FROM ARABIDOPSIS THALIANA AT5G18200 | ENSEMBLE REFINEMENT, REFINEMENT METHODOLOGY DEVELOPMENT, GALT, AT5G18200, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS, CESG, TRANSFERASE
4ifi:A (PRO1831) to (TYR1845) STRUCTURE OF HUMAN BRCA1 BRCT IN COMPLEX WITH BAAT PEPTIDE | CELL CYCLE, DISEASE MUTATION, DNA DAMAGE, DNA REPAIR, FATTY ACID BIOSYNTHESIS, LIGASE, LIPID SYNTHESIS, METAL-BINDING, NUCLEUS, PHOSPHOPROTEIN, TUMOR SUPPRESSOR, UBL CONJUGATION PATHWAY, ZINC- FINGER, BRCT DOMAIN, DNA DAMAGE RESPONSE, PHOSPHO PEPTIDE INTERACTIONS, DNA-BINDING, PHOSPHO PEPTIDE BINDING, TRANSCRIPTION
4igk:B (PRO1831) to (TYR1845) STRUCTURE OF HUMAN BRCA1 BRCT IN COMPLEX WITH ATRIP PEPTIDE | CELL CYCLE, DISEASE MUTATION, DNA DAMAGE, DNA REPAIR, FATTY ACID BIOSYNTHESIS, LIGASE, LIPID SYNTHESIS, METAL-BINDING, NUCLEUS, PHOSPHOPROTEIN, TUMOR SUPPRESSOR, UBL CONJUGATION PATHWAY, ZINC- FINGER, BRCT DOMAIN, DNA DAMAGE RESPONSE, PHOSPHO PEPTIDE INTERACTIONS, DNA-BINDING, PHOSPHO PEPTIDE BINDING, TRANSCRIPTION
3sw3:A (ASP221) to (ALA251) EDTA-FREE CRYSTAL STRUCTURE OF THE MUTANT C221D OF CARBAPENEMASE CPHA FROM AEROMONAS HYDROPHILA | HYDROLASE
1p3j:A (ARG79) to (VAL90) ADENYLATE KINASE FROM BACILLUS SUBTILIS | ZINC COORDINATION, TRANSFERASE
1p44:D (GLY192) to (GLY204) TARGETING TUBERCULOSIS AND MALARIA THROUGH INHIBITION OF ENOYL REDUCTASE: COMPOUND ACTIVITY AND STRUCTURAL DATA | INHA, SHORT CHAIN DEHYDROGENASE REDUCTASE, INHIBITOR, ROSSMANN FOLD, ENOYL-ACP REDUCTASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, OXIDOREDUCTASE
1p44:E (GLY192) to (GLY205) TARGETING TUBERCULOSIS AND MALARIA THROUGH INHIBITION OF ENOYL REDUCTASE: COMPOUND ACTIVITY AND STRUCTURAL DATA | INHA, SHORT CHAIN DEHYDROGENASE REDUCTASE, INHIBITOR, ROSSMANN FOLD, ENOYL-ACP REDUCTASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, OXIDOREDUCTASE
2cej:A (ASN83) to (GLY94) P1' EXTENDED HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMICKING SCAFFOLD | HIV-1, PROTEASE, INHIBITOR, ASPARTYL PROTEASE, HYDROLASE
4ii7:A (GLY313) to (ARG328) ARCHAELLUM ASSEMBLY ATPASE FLAI | HEXAMER, HYDROLASE, ATP/ADP, CYTOPLASMIC, MEMBRANE ASSOCIATED
1p5q:C (SER251) to (ASN262) CRYSTAL STRUCTURE OF FKBP52 C-TERMINAL DOMAIN | ISOMERASE
2qci:B (ASN183) to (GLY194) HIV-1 PROTEASE MUTANT D30N WITH POTENT ANTIVIRAL INHIBITOR GRL-98065 | HIV-1, MUTANT D30N, PROTEASE INHIBITOR, HYDROLASE
1d4h:B (ASN183) to (GLY194) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA435 | DIMER, HYDROLASE
1d4i:B (ASN183) to (GLY194) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA425 | DIMER, HYDROLASE
1d4j:B (ASN183) to (GLY194) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR MSL370 | DIMER, HYDROLASE
1d4y:B (ASN83) to (GLY94) HIV-1 PROTEASE TRIPLE MUTANT/TIPRANAVIR COMPLEX | HYDROLASE, ACID PROTEASE, ASPARTYL PROTEASE
2qd7:B (ASN183) to (GLY194) HIV-1 PROTEASE MUTANT V82A WITH POTENT ANTIVIRAL INHIBITOR GRL-98065 | HIV-1 PROTEASE MUTANT V82A, PROTEASE INHIBITOR, HYDROLASE
1p7l:A (HIS3) to (ASP34) S-ADENOSYLMETHIONINE SYNTHETASE COMPLEXED WITH AMPPNP AND MET. | S-ADENOSYLMETHIONINE SYNTHETASE, AMPPNP, SAM, TRANSFERASE
1p7l:B (HIS3) to (ASP34) S-ADENOSYLMETHIONINE SYNTHETASE COMPLEXED WITH AMPPNP AND MET. | S-ADENOSYLMETHIONINE SYNTHETASE, AMPPNP, SAM, TRANSFERASE
1p7l:C (HIS3) to (ASP34) S-ADENOSYLMETHIONINE SYNTHETASE COMPLEXED WITH AMPPNP AND MET. | S-ADENOSYLMETHIONINE SYNTHETASE, AMPPNP, SAM, TRANSFERASE
1p7l:D (HIS3) to (ASP34) S-ADENOSYLMETHIONINE SYNTHETASE COMPLEXED WITH AMPPNP AND MET. | S-ADENOSYLMETHIONINE SYNTHETASE, AMPPNP, SAM, TRANSFERASE
1p7p:A (ASP92) to (GLY117) METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH METHIONINE PHOSPHONATE | ROSSMANN FOLD, LIGASE
2qey:A (MET173) to (GLY185) RAT CYTOSOLIC PEPCK IN COMPLEX WITH GTP | PEPCK, PHOSPHOENOLPYRUVATE CARBOXYKINASE, GLUCONEOGENESIS, GTP, KINASE, LYASE
2qf2:B (MET173) to (GLY185) RAT CYTOSOLIC PEPCK IN COMPLEX WITH OXALOACETIC ACID AND GDP. | PEPCK, PHOSPHOENOLPYRUVATE CARBOXYKINASE, KINASE, OAA, GDP, GLUCONEOGENESIS, LYASE
4ike:B (ASN77) to (VAL87) CRYSTAL STRUCTURE OF A PARTLY OPEN ATP-LID OF LIGANDED ADENYLATE KINASE | TANSFERASE (PHOSPHOTRANSFERASE), PHOSPHORYL TRANSFER, NUCLEOTIDE BINDING, PHOSPHORYL TRANSFER OF NUCLEOTIDES, TRANSFERASE
1daz:C (ASN83) to (GLY94) STRUCTURAL AND KINETIC ANALYSIS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, REDUCED PEPTIDE INHIBITOR
4xqk:A (PHE408) to (ASP420) ATP-DEPENDENT TYPE ISP RESTRICTION-MODIFICATION ENZYME LLABIII BOUND TO DNA | ATP-DEPENDENT RESTRICTION-MODIFICATION ENZYME, TYPE ISP RESTRICTION- MODIFICATION ENZYME, ATPASE, HYDROLASE-DNA COMPLEX
1dbt:A (PHE31) to (GLU42) CRYSTAL STRUCTURE OF OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE FROM BACILLUS SUBTILIS COMPLEXED WITH UMP | DECARBOXYLASE, UMP, TIM BARREL, LYASE
1dbt:B (PHE31) to (GLU42) CRYSTAL STRUCTURE OF OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE FROM BACILLUS SUBTILIS COMPLEXED WITH UMP | DECARBOXYLASE, UMP, TIM BARREL, LYASE
1dbt:C (PHE31) to (GLU42) CRYSTAL STRUCTURE OF OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE FROM BACILLUS SUBTILIS COMPLEXED WITH UMP | DECARBOXYLASE, UMP, TIM BARREL, LYASE
2cin:A (CYS305) to (ALA317) LYSINE AMINOTRANSFERASE FROM M. TUBERCULOSIS IN THE INTERNAL ALDIMINE FORM | TRANSFERASE, INTERNAL ALDIMINE, PYRIDOXAL PHOSPHATE, PLP, RV3290C, AMINOTRANSFERASE, LYSINE AMINO TRANSFERASE, MYCOBACTERIUM TUBERCULOSIS
3g5i:B (GLY236) to (LEU249) CRYSTAL STRUCTURE OF THE E.COLI RIHA PYRIMIDINE NUCLEOSIDASE BOUND TO A IMINORIBITOL-BASED INHIBITOR | OPEN (ALPHA, BETA) STRUCTURE, GLYCOSIDASE, HYDROLASE
3g5i:C (GLY236) to (LEU249) CRYSTAL STRUCTURE OF THE E.COLI RIHA PYRIMIDINE NUCLEOSIDASE BOUND TO A IMINORIBITOL-BASED INHIBITOR | OPEN (ALPHA, BETA) STRUCTURE, GLYCOSIDASE, HYDROLASE
3g5i:D (GLY236) to (LEU249) CRYSTAL STRUCTURE OF THE E.COLI RIHA PYRIMIDINE NUCLEOSIDASE BOUND TO A IMINORIBITOL-BASED INHIBITOR | OPEN (ALPHA, BETA) STRUCTURE, GLYCOSIDASE, HYDROLASE
1ddg:A (GLU524) to (GLY536) CRYSTAL STRUCTURE OF SIR-FP60 | CYTOCHROME P450 REDUCTASE, FNR, FLAVOPROTEIN, MODULAR PROTEIN, OXIDOREDUCTASE
1ddg:B (GLU524) to (GLN535) CRYSTAL STRUCTURE OF SIR-FP60 | CYTOCHROME P450 REDUCTASE, FNR, FLAVOPROTEIN, MODULAR PROTEIN, OXIDOREDUCTASE
1ddi:A (GLU524) to (GLN535) CRYSTAL STRUCTURE OF SIR-FP60 | CYTOCHROME P450 REDUCTASE, FNR, FLAVOPROTEIN, MODULAR PROTEIN, OXIDOREDUCTASE
2qi0:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-1-KK80 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2qi0:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-1-KK80 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2qi4:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-2-AD93 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
2qi6:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF PROTEASE INHIBITOR, MIT-2-KB98 IN COMPLEX WITH WILD TYPE HIV-1 PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE
1dev:C (SER353) to (TYR366) CRYSTAL STRUCTURE OF SMAD2 MH2 DOMAIN BOUND TO THE SMAD- BINDING DOMAIN OF SARA | BETA SHEET, THREE-HELIX BUNDLE, SIGNALING PROTEIN
3g6j:C (HIS60) to (GLU77) C3B IN COMPLEX WITH A C3B SPECIFIC FAB | COMPLEMENT, C3B, FAB, ANTIBODY:ANTIGEN, AGE-RELATED MACULAR DEGENERATION, CLEAVAGE ON PAIR OF BASIC RESIDUES, COMPLEMENT ALTERNATE PATHWAY, COMPLEMENT PATHWAY, DISEASE MUTATION, GLYCOPROTEIN, IMMUNE RESPONSE, INFLAMMATORY RESPONSE, INNATE IMMUNITY, PHOSPHOPROTEIN, SECRETED, THIOESTER BOND, IMMUNE SYSTEM
3g6w:C (PRO2) to (ASP20) ASYMETRIC GTP BOUND STRUCTURE OF UPRTASE FROM SULFOLOBUS SOLFATARICUS CONTAINING PRPP-MG2+ IN HALF OF THE ACTIVE SITES AND R5P AND PPI IN THE OTHER HALF | ALLOSTERIC REGULATION, TETRAMER, SULFOLOBUS SOLFATARICUS, PHOSPHORIBOSYLTRANSFERASE, PRPP, R5P, GTP, POP, MAGNESIUM, GLYCOSYLTRANSFERASE, TRANSFERASE
3g7d:A (THR72) to (SER84) NATIVE PHPD WITH CADMIUM ATOMS | NON HEME FE(II) DIOXYGENASE, CUPIN, BIOSYNTHETIC PROTEIN
1pfv:A (ASP92) to (GLY117) METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH DIFLUOROMETHIONINE | ROSSMANN FOLD, LIGASE
1pfu:A (ASP92) to (GLY117) METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH METHIONINE PHOSPHINATE | ROSSMANN FOLD, LIGASE
1pfy:A (ASP92) to (GLY117) METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH METHIONYL SULPHAMOYL ADENOSINE | ROSSMANN FOLD, LIGASE
3gak:B (PRO44) to (ASP58) STRUCTURE OF GIARDIA FRUCTOSE-1,6-BIPHOSPHATE ALDOLASE | CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE, GLYCOLYTIC PATHWAY, GIARDIA LAMBLIA, DRUG TARGET, GLYCOLYSIS, LYASE
3gay:B (PRO44) to (ASP58) STRUCTURE OF GIARDIA FRUCTOSE-1,6-BIPHOSPHATE ALDOLASE IN COMPLEX WITH TAGATOSE-1,6-BIPHOSPHATE | CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE, GLYCOLYTIC PATHWAY, GIARDIA LAMBLIA, DRUG TARGET, GLYCOLYSIS, LYASE
2qmp:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH PL-100 | HIV-1 PROTEASE, ASPARTYL PROTEASE, HYDROLASE, MULTIFUNCTIONAL ENZYME, NUCLEOTIDYLTRANSFERASE, RNA- DIRECTED DNA POLYMERASE, TRANSFERASE
3gbf:A (THR72) to (SER84) PHPD WITH CADMIUM COMPLEXED WITH HYDROETHYLPHOSPHONATE (HEP) | ANTIBIOTIC BIOSYNTHESIS, IRON DEPENDENT OXYGENASE, BIOSYNTHETIC PROTEIN
1dm9:A (LEU84) to (THR108) HEAT SHOCK PROTEIN 15 KD | HEAT SHOCK PROTEINS, PROTEIN-RNA INTERACTIONS, RIBOSOME, STRUCTURAL GENOMICS
2qne:A (LEU204) to (ALA220) CRYSTAL STRUCTURE OF PUTATIVE METHYLTRANSFERASE (ZP_00558420.1) FROM DESULFITOBACTERIUM HAFNIENSE Y51 AT 2.30 A RESOLUTION | ZP_00558420.1, PUTATIVE METHYLTRANSFERASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, UNCHARACTERIZED PROTEIN, UNKNOWN FUNCTION, TRANSFERASE
2qnq:B (ASN83) to (GLY94) HIV-1 PROTEASE IN COMPLEX WITH A CHLORO DECORATED PYRROLIDINE-BASED INHIBITOR | PROTEIN-LIGAND COMPLEX, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, PHOSPHORYLATION, PROTEASE, RNA- BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER
4is4:G (HIS249) to (GLU259) THE GLUTAMINE SYNTHETASE FROM THE DICOTYLEDONOUS PLANT M. TRUNCATULA IS A DECAMER | DECAMER DICOTYLEDONOUS, LIGASE
2cu3:A (MSE1) to (GLY24) CRYSTAL STRUCTURE OF TT1568 FROM THERMUS THERMOPHILUS HB8 | THERMUS THERMOPHILUS HB8, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, UNKNOWN FUNCTION
3t4j:B (LEU319) to (LEU333) ARABIDOPSIS HISTIDINE KINASE 4 SENSOR DOMAIN IN COMPLEX WITH N- ISOPENTENYL ADENINE | SENSOR HISTIDINE KINASE, PAS DOMAIN, FAMILY 1 SENSOR DOMAIN, HORMONE RECEPTOR, CYTOKININ BINDING, ENDOPLASMIC RETICULUM
3t4k:B (LEU319) to (LEU333) ARABIDOPSIS HISTIDINE KINASE 4 SENSOR DOMAIN IN COMPLEX WITH N- BENZYLADENINE | SENSOR HISTIDINE KINASE, PAS DOMAIN, HORMONE RECEPTOR, ENDOPLASMIC RETICULUM
3t4l:B (LEU319) to (LEU333) ARABIDOPSIS HISTIDINE KINASE 4 SENSOR DOMAIN IN COMPLEX WITH TRANS- ZEATIN | SENSOR HISTIDINE KINASE, PAS DOMAIN, HORMONE RECEPTOR, ENDOPLASMIC RETICULUM
3t4o:B (LEU319) to (LEU333) ARABIDOPSIS HISTIDINE KINASE 4 SENSOR DOMAIN IN COMPLEX WITH DIHYDROZEATIN | SENSOR HISTIDINE KINASE, PAS DOMAIN, HORMONE RECEPTOR, ENDOPLASMIC RETICULUM
3t4s:B (LEU319) to (LEU333) ARABIDOPSIS HISTIDINE KINASE 4 SENSOR DOMAIN IN COMPLEX WITH KINETIN | SENSOR HISTIDINE KINASE, PAS DOMAIN, HORMONE RECEPTOR, ENDOPLASMIC RETICULUM
2qqk:L (THR109) to (GLY128) NEUROPILIN-2 A1A2B1B2 DOMAINS IN COMPLEX WITH A SEMAPHORIN-BLOCKING FAB | VEGF RECEPTOR, SEMAPHORIN RECEPTOR, PHAGE-DERIVED ANTIBODY, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, GLYCOPROTEIN, MEMBRANE, NEUROGENESIS, TRANSMEMBRANE, HORMONE, SIGNALING PROTEIN
4xxo:A (GLY65) to (GLN83) CRYSTAL STRUCTURE OF HUMAN APOBEC3A | APOBEC, APOBEC3, DEAMINASE, DEAMINATION, APOLIPOPROTEIN B MRNA EDITING POLYPEPTIDE-LIKE 3, HYDROLASE
3gga:C (ASN83) to (GLY94) HIV PROTEASE INHIBITORS WITH PSEUDO-SYMMETRIC CORES | PSEUDO-SYMMETRICAL HIV PROTEASE INHIBITORS, HYDROLASE, PROTEASE
3ggv:A (ASN83) to (GLY94) HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS | HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE
3gi0:B (ASN187) to (GLY198) CRYSTAL STRUCTURE OF A CHEMICALLY SYNTHESIZED 203 AMINO ACID 'COVALENT DIMER' [L-ALA51,D-ALA51'] HIV-1 PROTEASE MOLECULE COMPLEXED WITH JG- 365 INHIBITOR | BETA-BARREL, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2qtm:A (GLY81) to (TYR96) CRYSTAL STRUCTURE OF NICOTINATE MONONUCLEOTIDE ADENYLYLTRANSFERASE | NAD, NUCLEOTIDYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS, TRANSFERASE
2qun:D (GLY60) to (ASP74) CRYSTAL STRUCTURE OF D-TAGATOSE 3-EPIMERASE FROM PSEUDOMONAS CICHORII IN COMPLEX WITH D-FRUCTOSE | BETA/ALPHA BARREL, ISOMERASE
1pro:A (ASN83) to (GLY94) HIV-1 PROTEASE DIMER COMPLEXED WITH A-98881 | AIDS, POLYPROTEIN, HYDROLASE, ASPARTIC PROTEASE, ENDONUCLEASE, RNA-DIRECTED DNA POLYMERASE, HYDROLASE (ASPARTIC PROTEASE)
1dzr:A (SER30) to (ILE40) RMLC FROM SALMONELLA TYPHIMURIUM | ISOMERASE, 3\,5-HEXULOSE EPIMERASE
1dzr:A (GLU144) to (ALA173) RMLC FROM SALMONELLA TYPHIMURIUM | ISOMERASE, 3\,5-HEXULOSE EPIMERASE
1dzr:B (SER30) to (ILE40) RMLC FROM SALMONELLA TYPHIMURIUM | ISOMERASE, 3\,5-HEXULOSE EPIMERASE
1dzt:A (SER30) to (GLY41) RMLC FROM SALMONELLA TYPHIMURIUM | ISOMERASE, 3\,5 HEXULOSE EPIMERASE
1dzt:B (SER30) to (ILE40) RMLC FROM SALMONELLA TYPHIMURIUM | ISOMERASE, 3\,5 HEXULOSE EPIMERASE
3t9m:A (ASP221) to (ALA251) CRYSTAL STRUCTURE OF MUTANT C221D OF CARBAPENEMASE CPHA FROM AEROMONAS HYDROPHILA | HYDROLASE
4y15:C (GLY91) to (GLY114) SDIA IN COMPLEX WITH 3-OXO-C6-HOMOSERINE LACTONE | QUORUM SENSOR, DNA BINDING PROTEIN
2d2i:O (ALA148) to (LEU160) CRYSTAL STRUCTURE OF NADP-DEPENDENT GLYCERALDEHYDE-3- PHOSPHATE DEHYDROGENASE FROM SYNECHOCOCCUS SP. COMPLEXED WITH NADP+ | GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE, ROSSMANN FOLD, PROTEIN-NADP+ COMPLEX, OXIDOREDUCTASE
3gn3:B (THR154) to (GLY179) CRYSTAL STRUCTURE OF A PUTATIVE PROTEIN-DISULFIDE ISOMERASE FROM PSEUDOMONAS SYRINGAE TO 2.5A RESOLUTION. | DISULFIDE, ISOMERASE, PSEUDOMONAS, MCSG, PSI, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, UNKNOWN FUNCTION
4y2m:A (GLY0) to (CYS10) APO-GOLB PROTEIN | OXIDIZED FORM, GOLD BINDING PROTEIN, METAL TRANSPORT
3gn4:D (GLY134) to (THR146) MYOSIN LEVER ARM | UNCONVENTIONAL MYOSIN, MOTILITY, LEVER ARM, 3-HELIX BUNDLE, ACTIN-BINDING, ATP-BINDING, CALMODULIN-BINDING, COILED COIL, CYTOPLASM, ENDOCYTOSIS, GOLGI APPARATUS, HEARING, MEMBRANE, MOTOR PROTEIN, MYOSIN, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTEIN TRANSPORT, TRANSPORT, ACETYLATION, CALCIUM, MOTOR PROTEIN/METAL BINDING PROTEIN COMPLEX
4j12:A (GLN342) to (ASN361) MONOMERIC FC | IMMUNOGLOBULIN FOLD, IMMUNE SYSTEM
1e2s:P (LEU330) to (GLY345) CRYSTAL STRUCTURE OF AN ARYLSULFATASE A MUTANT C69A | HYDROLASE, CEREBROSIDE-3-SULFATE HYDROLYSIS, LYSOSOMAL ENZYME, FORMYLGLYCINE
1e33:P (LEU330) to (GLY345) CRYSTAL STRUCTURE OF AN ARYLSULFATASE A MUTANT P426L | HYDROLASE, CEREBROSIDE-3-SULFATE HYDROLYSIS, LYSOSOMAL ENZYME, FORMYLGLYCINE
2qzy:A (MET193) to (LEU204) THE STRUCTURE OF CHICKEN MITOCHONDRIAL PEPCK IN COMPLEX WITH PEP | PEPCK, KINASE, DECARBOXYLASE, GLUCONEOGENESIS, GTP-BINDING, LYASE, MANGANESE, MITOCHONDRION, NUCLEOTIDE-BINDING, TRANSIT PEPTIDE
2d5b:A (ASP90) to (GLY115) CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS METHIONYL TRNA SYNTHETASE Y225F MUTANT OBTAINED IN THE PRESENCE OF PEG6000 | ROSSMANN FOLD, CLASS 1A AARS, ISOMERASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
1e4k:A (GLN342) to (ASN361) CRYSTAL STRUCTURE OF SOLUBLE HUMAN IGG1 FC FRAGMENT-FC-GAMMA RECEPTOR III COMPLEX | IMMUNE SYSTEM, FC FRAGMENT, IGG, RECEPTOR,
1e5q:A (VAL420) to (GLY441) TERNARY COMPLEX OF SACCHAROPINE REDUCTASE FROM MAGNAPORTHE GRISEA, NADPH AND SACCHAROPINE | OXIDOREDUCTASE, SACCHAROPINE REDUCTASE, NADPH, LYSINE BIOSYNTHESIS, ALPHA- AMINOADIPATE PATHWAY
2r3w:B (ASN83) to (GLY94) I84V HIV-1 PROTEASE IN COMPLEX WITH A AMINO DECORATED PYRROLIDINE-BASED INHIBITOR | PROTEIN-LIGAND COMPLEX, HYDROLASE
2r43:B (ASN83) to (GLY94) I50V HIV-1 PROTEASE IN COMPLEX WITH AN AMINO DECORATED PYRROLIDINE- BASED INHIBITOR | PROTEIN-LIGAND COMPLEX, HYDROLASE
4y6m:A (GLY122) to (ASN147) STRUCTURE OF PLASMEPSIN II FROM PLASMODIUM FALCIPARUM COMPLEXED WITH INHIBITOR PG418 | PLASMEPSIN II HYDROXYETHYLAMINE-BASD INHIBITOR, HYDROLASE
1q0b:B (ILE19) to (SER36) CRYSTAL STRUCTURE OF THE MOTOR PROTEIN KSP IN COMPLEX WITH ADP AND MONASTROL | CELL CYCLE, MOTOR PROTEIN, MONASTROL
2r5p:A (ASN83) to (GLY94) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 SUBTYPE C PROTEASE COMPLEXED WITH INDINAVIR | HIV-1 SUBTYPE C, ASPARTYL PROTEASE, HYDROLASE, PROTEASE, VIRAL PROTEIN
2r5p:C (ASN83) to (GLY94) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 SUBTYPE C PROTEASE COMPLEXED WITH INDINAVIR | HIV-1 SUBTYPE C, ASPARTYL PROTEASE, HYDROLASE, PROTEASE, VIRAL PROTEIN
4y77:F (HIS224) to (ASN244) YEAST 20S PROTEASOME IN COMPLEX WITH AC-LAF-EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, INHIBITOR, BINDING ANALYSIS
4y77:T (HIS224) to (ASN244) YEAST 20S PROTEASOME IN COMPLEX WITH AC-LAF-EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, INHIBITOR, BINDING ANALYSIS
2dfs:E (GLY134) to (ALA147) 3-D STRUCTURE OF MYOSIN-V INHIBITED STATE | MYOSIN-V, INHIBITED STATE, CALMODULIN, CRYOELECTRON TOMOGRAPHY, CONTRACTILE PROTEIN-TRANSPORT PROTEIN COMPLEX
2dfs:G (GLY134) to (ALA147) 3-D STRUCTURE OF MYOSIN-V INHIBITED STATE | MYOSIN-V, INHIBITED STATE, CALMODULIN, CRYOELECTRON TOMOGRAPHY, CONTRACTILE PROTEIN-TRANSPORT PROTEIN COMPLEX
2dfs:Q (GLY134) to (ALA147) 3-D STRUCTURE OF MYOSIN-V INHIBITED STATE | MYOSIN-V, INHIBITED STATE, CALMODULIN, CRYOELECTRON TOMOGRAPHY, CONTRACTILE PROTEIN-TRANSPORT PROTEIN COMPLEX
2dfs:S (GLY134) to (ALA147) 3-D STRUCTURE OF MYOSIN-V INHIBITED STATE | MYOSIN-V, INHIBITED STATE, CALMODULIN, CRYOELECTRON TOMOGRAPHY, CONTRACTILE PROTEIN-TRANSPORT PROTEIN COMPLEX
1q25:A (SER168) to (CYS190) CRYSTAL STRUCTURE OF N-TERMINAL 3 DOMAINS OF CI-MPR | P-LECTIN, RECEPTOR, MANNOSE 6-PHOSPHATE, PROTEIN TRANSPORT,SUGAR BINDING PROTEIN
4y7p:A (PHE68) to (ASN91) STRUCTURE OF ALKALINE D-PEPTIDASE FROM BACILLUS CEREUS | PENICILLIN BINDING PROTEIN, APO FORM, HYDROLASE
3gtk:B (ASP837) to (GLY849) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 18MER RNA | TRANSCRIPTION, TRANSFERASE/DNA-RNA HYBRID, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR
1q3g:K (PHE80) to (MET90) MURA (ASP305ALA) LIGANDED WITH TETRAHEDRAL REACTION INTERMEDIATE | INSIDE-OUT ALPHA-BETA BARREL, TRANSFERASE
1q3g:Y (PHE80) to (MET90) MURA (ASP305ALA) LIGANDED WITH TETRAHEDRAL REACTION INTERMEDIATE | INSIDE-OUT ALPHA-BETA BARREL, TRANSFERASE
4y8e:A (ASP178) to (ILE190) PA3825-EAL CA-APO STRUCTURE | EAL, METAL BINDING PROTEIN
4y8g:F (HIS224) to (ASN244) YEAST 20S PROTEASOME IN COMPLEX WITH N3-APNLL-EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, INHIBITOR, BINDING ANALYSIS
4y8g:T (HIS224) to (ASN244) YEAST 20S PROTEASOME IN COMPLEX WITH N3-APNLL-EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, INHIBITOR, BINDING ANALYSIS
4y8h:F (HIS224) to (ASN244) YEAST 20S PROTEASOME IN COMPLEX WITH N3-APAL-EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, INHIBITOR, BINDING ANALYSIS
4y8h:T (HIS224) to (ASN244) YEAST 20S PROTEASOME IN COMPLEX WITH N3-APAL-EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, INHIBITOR, BINDING ANALYSIS
3gtp:B (LYS404) to (VAL436) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 24MER RNA | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA- DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, TRANSFERASE/DNA-RNA HYBRID COMPLEX
3tix:B (GLY812) to (THR824) CRYSTAL STRUCTURE OF THE CHP1-TAS3 COMPLEX CORE | PIN, ROSSMANN FOLD, SPOC, ALPHA-HELICAL HAIRPIN, HETEROCHROMATIN, SILENCING, RITS, RNAI, ARGONAUTE, CLRC, RDRC, NUCLEUS, GENE REGULATION-PROTEIN BINDING COMPLEX
1ebw:B (ASN183) to (GLY194) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA322 | DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1eby:A (ASN83) to (GLY94) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA369 | DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1eby:B (ASN183) to (GLY194) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA369 | DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1ec0:B (ASN183) to (GLY194) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA403 | DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
4y8s:F (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA2-H116D MUTANT IN COMPLEX WITH AC-LAE-EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
4y8t:F (HIS224) to (ILE243) YEAST 20S PROTEASOME BETA2-H116D MUTANT IN COMPLEX WITH AC-PAE-EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
4y8t:T (HIS224) to (ILE243) YEAST 20S PROTEASOME BETA2-H116D MUTANT IN COMPLEX WITH AC-PAE-EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
3tkg:D (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV MODEL PROTEASE PRECURSOR/SAQUINAVIR COMPLEX | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3tkw:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV PROTEASE MODEL PRECURSOR/DARUNAVIR COMPLEX | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4y9q:A (GLY50) to (GLY65) PA3825-EAL MG-CDG STRUCTURE | EAL, CYCLIC DI-GMP, UNKNOWN FUNCTION
4jdk:A (PRO470) to (ARG489) CRYSTAL STRUCTURE OF SERINE/THREONINE-PROTEIN KINASE PAK 4 F461V MUTANT IN COMPLEX WITH PAKTIDE S PEPTIDE SUBSTRATE | TRANSFERASE-PEPTIDE COMPLEX, TRANSFERASE/PEPTIDE, SERINE/THREONINE- PROTEIN KINASE PAK4, ATP BINDING, PHOSPHORYLATION
4y9u:A (HIS601) to (ARG613) RAT CYPOR MUTANT - G143DEL | CYTOCHROME P450 REDUCTASE, FMN BINDING, SEMIQUINONE, OXIDOREDUCTASE
4y9u:B (HIS601) to (ASP612) RAT CYPOR MUTANT - G143DEL | CYTOCHROME P450 REDUCTASE, FMN BINDING, SEMIQUINONE, OXIDOREDUCTASE
1edz:A (ARG6) to (ASN18) STRUCTURE OF THE NAD-DEPENDENT 5,10- METHYLENETETRAHYDROFOLATE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE | NUCLEOTIDE-BINDING DOMAIN, MONOFUNCTIONAL, DEHYDROGENASE, FOLATE, OXIDOREDUCTASE
3tl8:A (LYS275) to (SER286) THE AVRPTOB-BAK1 COMPLEX REVEALS TWO STRUCTURALLY SIMILAR KINASEINTERACTING DOMAINS IN A SINGLE TYPE III EFFECTOR | PLANT IMMUNITY, PSEUDOMONAS SYRINGAE, SOLANUM LYCOPERSICUM, PAMP- TRIGGERED IMMUNITY, BACTERIAL PATHOGENESIS, TRANSFERASE-LIGASE COMPLEX
3tl8:D (LEU274) to (SER286) THE AVRPTOB-BAK1 COMPLEX REVEALS TWO STRUCTURALLY SIMILAR KINASEINTERACTING DOMAINS IN A SINGLE TYPE III EFFECTOR | PLANT IMMUNITY, PSEUDOMONAS SYRINGAE, SOLANUM LYCOPERSICUM, PAMP- TRIGGERED IMMUNITY, BACTERIAL PATHOGENESIS, TRANSFERASE-LIGASE COMPLEX
1ef5:A (SER671) to (ASN687) SOLUTION STRUCTURE OF THE RAS-BINDING DOMAIN OF RGL | RAS-BINDING DOMAIN, RGL, RAS, RBD, RA, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, SIGNALING PROTEIN
2r9b:A (GLY122) to (ASN147) STRUCTURAL ANALYSIS OF PLASMEPSIN 2 FROM PLASMODIUM FALCIPARUM COMPLEXED WITH A PEPTIDE-BASED INHIBITOR | BETA FOLD ASPARTYL PROTEASE, GLYCOPROTEIN, VACUOLE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ya9:F (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA2-H114D MUTANT IN COMPLEX WITH AC-LAD-EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
4ya9:T (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA2-H114D MUTANT IN COMPLEX WITH AC-LAD-EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
4yaf:A (HIS601) to (ARG613) RAT CYPOR WITH 2'-AMP | CYTOCHROME P450 REDUCTASE, FMN BINDING, SEMIQUINONE, OXIDOREDUCTASE
4yaf:B (HIS601) to (ARG613) RAT CYPOR WITH 2'-AMP | CYTOCHROME P450 REDUCTASE, FMN BINDING, SEMIQUINONE, OXIDOREDUCTASE
3to6:A (ILE402) to (ALA418) CRYSTAL STRUCTURE OF YEAST ESA1 HAT DOMAIN COMPLEXED WITH H4K16COA BISUBSTRATE INHIBITOR | ACETYLTRANSFERASE, AUTOACETYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3to7:A (ILE402) to (ALA418) CRYSTAL STRUCTURE OF YEAST ESA1 HAT DOMAIN BOUND TO COENZYME A WITH ACTIVE SITE LYSINE ACETYLATED | MYST FAMILY, HISTONE ACETYLTRANSFERASE, TRANSFERASE
3to9:A (ILE402) to (ALA418) CRYSTAL STRUCTURE OF YEAST ESA1 E338Q HAT DOMAIN BOUND TO COENZYME A WITH ACTIVE SITE LYSINE ACETYLATED | MYST FAMILY, TRANSFERASE
3tof:B (ASN83) to (GLY94) HIV-1 PROTEASE - EPOXYDIC INHIBITOR COMPLEX (PH 6 - ORTHOROMBIC CRYSTAL FORM P212121) | HIV PR, EPOXIDE, IN-CRYSTAL REACTION, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3tog:C (ASN83) to (GLY94) HIV-1 PROTEASE - EPOXYDIC INHIBITOR COMPLEX (PH 9 - MONOCLINIC CRYSTAL FORM P21) | HIV PR, EPOXIDE, IN-CRYSTAL REACTION, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3toh:B (ASN83) to (GLY94) HIV-1 PROTEASE - EPOXYDIC INHIBITOR COMPLEX (PH 9 - ORTHOROMBIC CRYSTAL FORM P212121) | HIV PR, EPOXIDE, IN-CRYSTAL REACTION, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4yal:A (HIS601) to (ARG613) REDUCED CYPOR WITH 2'-AMP | CYTOCHROME P450 REDUCTASE, FMN BINDING, SEMIQUINONE, OXIDOREDUCTASE
4yao:B (HIS601) to (ARG613) REDUCED CYPOR MUTANT - G143DEL | CYTOCHROME P450 REDUCTASE, FMN BINDING, SEMIQUINONE, OXIDOREDUCTASE
4yar:A (THR72) to (SER84) 2-HYDROXYETHYLPHOSPHONATE DIOXYGENASE (HEPD) E176H | DIOXYGENASE
3gy9:A (THR136) to (ASN148) CRYSTAL STRUCTURE OF PUTATIVE ACETYLTRANSFERASE (YP_001815201.1) FROM EXIGUOBACTERIUM SP. 255-15 AT 1.52 A RESOLUTION | YP_001815201.1, PUTATIVE ACETYLTRANSFERASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, TRANSFERASE, UNKNOWN FUNCTION
3gya:A (THR136) to (SER147) CRYSTAL STRUCTURE OF PUTATIVE ACETYLTRANSFERASE (YP_001815201.1) FROM EXIGUOBACTERIUM SP. 255-15 AT 1.62 A RESOLUTION | YP_001815201.1, PUTATIVE ACETYLTRANSFERASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, TRANSFERASE, UNKNOWN FUNCTION
4yau:A (HIS601) to (ARG613) REDUCED CYPOR MUTANT - G141DEL/E142N | CYTOCHROME P450 REDUCTASE, FMN BINDING, SEMIQUINONE, OXIDOREDUCTASE
4yaw:A (HIS601) to (ARG613) REDUCED CYPOR MUTANT - G141DEL | CYTOCHROME P450 REDUCTASE, FMN BINDING, SEMIQUINONE, OXIDOREDUCTASE
1qbt:A (ASN83) to (GLY94) HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY | HYDROLASE (ACID PROTEINASE), ASPARTYL PROTEASE
1qdm:A (VAL6) to (SER26) CRYSTAL STRUCTURE OF PROPHYTEPSIN, A ZYMOGEN OF A BARLEY VACUOLAR ASPARTIC PROTEINASE. | ASPARTIC PROTEINASES, PHYTEPSIN, SAPOSIN-LIKE DOMAIN, ZYMOGEN STRUCTURE, HYDROLASE
4jjm:B (ALA124) to (LYS132) STRUCTURE OF A CYCLOPHILIN FROM CITRUS SINENSIS (CSCYP) IN COMPLEX WITH CYCLOPORIN A | CYCLOPHILIN, ISOMERASE-IMMUNOSUPPRESSANT COMPLEX
4yed:B (PHE238) to (GLN267) TCDA (CSDL) | N6-THREONYLCARBAMOYLADENOSINE DEHYDRATASE TRNA MODIFICATION, LIGASE
4yed:C (PHE238) to (GLN267) TCDA (CSDL) | N6-THREONYLCARBAMOYLADENOSINE DEHYDRATASE TRNA MODIFICATION, LIGASE
4yed:D (PHE238) to (GLN267) TCDA (CSDL) | N6-THREONYLCARBAMOYLADENOSINE DEHYDRATASE TRNA MODIFICATION, LIGASE
1ems:A (ASP256) to (ARG280) CRYSTAL STRUCTURE OF THE C. ELEGANS NITFHIT PROTEIN | WORM, NITRILASE, FHIT, NUCLEOTIDE-BINDING PROTEIN, CANCER, DIADENOSINE POLYPHOSPHATE HYDROLASE, HISTIDINE TRIAD, TUMOR SUPPRESSOR, ROSETTA STONE, ANTITUMOR PROTEIN
4jk2:C (GLY266) to (ASP281) X-RAY CRYSTAL STRUCTURE OF ESCHERICHIA COLI SIGMA70 HOLOENZYME IN COMPLEX WITH GUANOSINE PENTAPHOSPHATE (PPPGPP) | TRANSCRIPTION, DNA, TRANSFERASE
1qkc:A (SER49) to (HIS61) ESCHERICHIA COLI FERRIC HYDROXAMATE UPTAKE RECEPTOR (FHUA) IN COMPLEX DELTA TWO-ALBOMYCIN | TONB DEPENDENT RECEPTOR, TONB-DEPENDENT RECEPTOR, INTEGRAL OUTER MEMBRANE PROTEIN, FERRICHROME, SIDEROPHORE RECEPTOR, ANTIBIOTIC, ALBOMYCIN, ACTIVE TRANSPORTER, IRON TRANSPORT PROTEIN
2rkd:A (MET173) to (GLY185) THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH 3- PHOSPHONOPROPIONATE | KINASE, GLUCONEOGENESIS, LYASE, DECARBOXYLASE, GTP-BINDING, NUCLEOTIDE-BINDING
2rkg:A (ASN84) to (GLY95) HIV-1 PR RESISTANT MUTANT + LPV | RESISTENCE, INSERTION, HYDROLASE
1qm4:A (PHE19) to (ASP50) METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH A L-METHIONINE ANALOGOUS | TRANSFERASE, ADENOSYLTRANSFERASE, METHIONINE BINDING
1qm4:B (PHE19) to (ASP50) METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH A L-METHIONINE ANALOGOUS | TRANSFERASE, ADENOSYLTRANSFERASE, METHIONINE BINDING
2rpp:A (LEU21) to (GLY32) SOLUTION STRUCTURE OF TANDEM ZINC FINGER DOMAIN 12 IN MUSCLEBLIND-LIKE PROTEIN 2 | ZINC FINGER DOMAIN, C3H, ALTERNATIVE SPLICING, CYTOPLASM, METAL-BINDING, NUCLEUS, RNA-BINDING, ZINC, ZINC-FINGER, TRANSCRIPTION, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
1ewf:A (GLY4) to (ILE32) THE 1.7 ANGSTROM CRYSTAL STRUCTURE OF BPI | BACTERICIDAL, PERMEABILITY-INCREASING, LIPID-BINDING, LIPOPOLYSACCHARIDE-BINDING, ANTIBIOTIC
1exf:A (GLY228) to (LYS241) EXFOLIATIVE TOXIN A | COMPLEX (TOXIN/PEPTIDE), HYDROLASE, SERINE PROTEASE, SUPERANTIGEN
4jr5:B (THR468) to (ALA480) STRUCTURE-BASED IDENTIFICATION OF UREAS AS NOVEL NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) INHIBITORS | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1qpn:A (ALA168) to (GLY180) QUINOLINATE PHOSPHORIBOSYL TRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH NCNN | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, NAMN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpn:B (ALA668) to (GLY680) QUINOLINATE PHOSPHORIBOSYL TRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH NCNN | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, NAMN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpn:D (ALA1668) to (GLY1680) QUINOLINATE PHOSPHORIBOSYL TRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH NCNN | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, NAMN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpn:F (ALA2668) to (GLY2680) QUINOLINATE PHOSPHORIBOSYL TRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH NCNN | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, NAMN, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpo:A (ALA168) to (GLY180) QUINOLINATE PHOSPHORIBOSYL TRANSFERASE (QAPRTASE) APO-ENZYME FROM MYCOBACTERIUM TUBERCULOSIS | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpo:B (ALA668) to (GLY680) QUINOLINATE PHOSPHORIBOSYL TRANSFERASE (QAPRTASE) APO-ENZYME FROM MYCOBACTERIUM TUBERCULOSIS | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpo:C (ALA1168) to (GLY1180) QUINOLINATE PHOSPHORIBOSYL TRANSFERASE (QAPRTASE) APO-ENZYME FROM MYCOBACTERIUM TUBERCULOSIS | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpo:D (ALA1668) to (GLY1680) QUINOLINATE PHOSPHORIBOSYL TRANSFERASE (QAPRTASE) APO-ENZYME FROM MYCOBACTERIUM TUBERCULOSIS | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpo:E (ALA2168) to (GLY2180) QUINOLINATE PHOSPHORIBOSYL TRANSFERASE (QAPRTASE) APO-ENZYME FROM MYCOBACTERIUM TUBERCULOSIS | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpo:F (ALA2668) to (GLY2680) QUINOLINATE PHOSPHORIBOSYL TRANSFERASE (QAPRTASE) APO-ENZYME FROM MYCOBACTERIUM TUBERCULOSIS | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpq:A (ALA168) to (GLY180) STRUCTURE OF QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS: A POTENTIAL TB DRUG TARGET | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpq:B (ALA668) to (GLY680) STRUCTURE OF QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS: A POTENTIAL TB DRUG TARGET | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpq:C (ALA1168) to (GLY1180) STRUCTURE OF QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS: A POTENTIAL TB DRUG TARGET | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpq:D (ALA1668) to (GLY1680) STRUCTURE OF QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS: A POTENTIAL TB DRUG TARGET | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpq:F (ALA2668) to (GLY2680) STRUCTURE OF QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS: A POTENTIAL TB DRUG TARGET | TYPE II PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, PHOSPHORIBOSYL TRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1qpr:C (ALA168) to (ALA179) QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (QAPRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH PHTHALATE AND PRPCP | PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, TRANSFERASE, PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC
1qpr:E (ALA168) to (ALA179) QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (QAPRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH PHTHALATE AND PRPCP | PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, TRANSFERASE, PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC
1qpr:F (ALA168) to (ALA179) QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (QAPRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH PHTHALATE AND PRPCP | PRTASE, DE NOVO NAD BIOSYNTHESIS, PRPP, TRANSFERASE, PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC
4yi9:A (GLY42) to (PRO58) CRYSTAL STRUCTURE OF NON-MYRISTOYLATED E153A RECOVERIN AT 1.35 A RESOLUTION WITH A SODIUM ION BOUND TO EF-HAND 2 AND CALCIUM ION BOUND TO EF-HAND 3 | CALCIUM BINDING PROTEIN, EF HAND, NCS FAMILY
4jsd:A (GLY79) to (GLU96) THE X-RAY CRYSTAL STRUCTURE OF A THERMOPHILIC CELLOBIOSE BINDING PROTEIN BOUND WITH LAMINARIBIOSE | PERIPLASMIC BINDING PROTEIN, THERMOPHILIC PROTEIN, CELLULOSE, SUGAR BINDING PROTEIN, CELLOBIOSE BINDING PROTEIN
3h6x:A (SER81) to (ASN92) CRYSTAL STRUCTURE OF DUTPASE FROM STREPTOCOCCUS MUTANS | JELLY-ROLL BETA-BARREL, HYDROLASE
4jsu:F (HIS224) to (ILE243) YEAST 20S PROTEASOME IN COMPLEX WITH THE DIMERIZED LINEAR MIMETIC OF TMC-95A - YCP:3A | UPS, PROTEASOME, DRUG DISCOVERY, NON-COVALENT REVERSIBLE INHIBITION, BIVALENCE, TMC-95A DERIVATIVES, NTN HYDROLASE, NON-LYSOSOMAL PROTEIN BREAKDOWN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4jsu:T (HIS224) to (ILE243) YEAST 20S PROTEASOME IN COMPLEX WITH THE DIMERIZED LINEAR MIMETIC OF TMC-95A - YCP:3A | UPS, PROTEASOME, DRUG DISCOVERY, NON-COVALENT REVERSIBLE INHIBITION, BIVALENCE, TMC-95A DERIVATIVES, NTN HYDROLASE, NON-LYSOSOMAL PROTEIN BREAKDOWN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3h76:A (LEU179) to (LEU192) CRYSTAL STRUCTURE OF PQSD, A KEY ENZYME IN PSEUDOMONAS AERUGINOSA QUINOLONE SIGNAL BIOSYNTHESIS PATHWAY | PQSD, PQS, ANTHRANILOYL-COA, ANTHRANILIC ACID, TRANSFERASE
3h76:B (LEU179) to (LEU192) CRYSTAL STRUCTURE OF PQSD, A KEY ENZYME IN PSEUDOMONAS AERUGINOSA QUINOLONE SIGNAL BIOSYNTHESIS PATHWAY | PQSD, PQS, ANTHRANILOYL-COA, ANTHRANILIC ACID, TRANSFERASE
3u0i:A (LEU2) to (LYS18) CRYSTAL STRUCTURE OF A PROBABLE FAD-BINDING, PUTATIVE UNCHARACTERIZED PROTEIN FROM BRUCELLA MELITENSIS | SSGCID, EMERALD BIOSTRUCTURES, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, FMN-BINDING PROTEIN, UNKNOWN FUNCTION
3h77:A (LEU179) to (LEU192) CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA PQSD IN A COVALENT COMPLEX WITH ANTHRANILATE | PQSD, PQS, ANTHRANILOYL-COA, ANTHRANILIC ACID, ANTHRANILATE MODIFIED CYS, TRANSFERASE
3h77:B (LEU179) to (LEU192) CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA PQSD IN A COVALENT COMPLEX WITH ANTHRANILATE | PQSD, PQS, ANTHRANILOYL-COA, ANTHRANILIC ACID, ANTHRANILATE MODIFIED CYS, TRANSFERASE
3h78:B (LEU179) to (LEU192) CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA PQSD C112A MUTANT IN COMPLEX WITH ANTHRANILIC ACID | PQSD, PQS, ANTHRANILIC ACID, ANTHRANILOYL-COA, TRANSFERASE
1qvr:A (THR702) to (GLY722) CRYSTAL STRUCTURE ANALYSIS OF CLPB | COILED COIL, AAA ATPASE, CHAPERONE
1qvr:B (THR702) to (GLY722) CRYSTAL STRUCTURE ANALYSIS OF CLPB | COILED COIL, AAA ATPASE, CHAPERONE
1qvr:C (LEU519) to (THR534) CRYSTAL STRUCTURE ANALYSIS OF CLPB | COILED COIL, AAA ATPASE, CHAPERONE
1qvr:C (THR702) to (GLY722) CRYSTAL STRUCTURE ANALYSIS OF CLPB | COILED COIL, AAA ATPASE, CHAPERONE
1qwi:D (GLN32) to (GLY42) CRYSTAL STRUCTURE OF E. COLI OSMC | HYDROPEROXIDE RESISTANCE, HYDROPEROXIDE REDUCTASE
1f4l:A (ASP92) to (GLY117) CRYSTAL STRUCTURE OF THE E.COLI METHIONYL-TRNA SYNTHETASE COMPLEXED WITH METHIONINE | ROSSMANN FOLD, ZINC DOMAIN, AMINO ACID, TRNA, HYDROLASE
4jtd:A (CYS51) to (THR65) CRYSTAL STRUCTURE OF KV1.2-2.1 PADDLE CHIMERA CHANNEL IN COMPLEX WITH LYS27MET MUTANT OF CHARYBDOTOXIN | POTASSIUM CHANNEL, PORE BLOCKING TOXIN, PROTEIN-PROTEIN COMPLEX, TRANS-ENHANCED DISSOCIATION EFFECT, TRANSPORT PROTEIN-TOXIN COMPLEX
4jtd:G (CYS51) to (THR65) CRYSTAL STRUCTURE OF KV1.2-2.1 PADDLE CHIMERA CHANNEL IN COMPLEX WITH LYS27MET MUTANT OF CHARYBDOTOXIN | POTASSIUM CHANNEL, PORE BLOCKING TOXIN, PROTEIN-PROTEIN COMPLEX, TRANS-ENHANCED DISSOCIATION EFFECT, TRANSPORT PROTEIN-TOXIN COMPLEX
1f7a:B (ASN83) to (GLY94) HOW DOES A SYMMETRIC DIMER RECOGNIZE AN ASYMMETRIC SUBSTRATE? A SUBSTRATE COMPLEX OF HIV-1 PROTEASE. | CAPSID, SUBSTRATE RECOGNITION, HYDROLASE
1qye:A (LYS72) to (LEU93) CRYSTAL STRUCTURE OF THE N-DOMAIN OF THE ER HSP90 CHAPERONE GRP94 IN COMPLEX WITH 2-CHLORODIDEOXYADENOSINE | GRP94, GP96, HSP90, 2CLDDA, 2-CHLORODIDEOXYADENOSINE, CHAPERONE
1qz2:C (SER251) to (ASN262) CRYSTAL STRUCTURE OF FKBP52 C-TERMINAL DOMAIN COMPLEX WITH THE C-TERMINAL PEPTIDE MEEVD OF HSP90 | ISOMERASE, ROTAMASE, CHAPERONE, HEAT SHOCK, ISOMERASE/CHAPERONE COMPLEX
3u5w:A (LEU2) to (LYS18) CRYSTAL STRUCTURE OF A PROBABLE FAD-BINDING, PUTATIVE UNCHARACTERIZED PROTEIN FROM BRUCELLA MELITENSIS, APO FORM | SSGCID, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, FMN-BINDING PROTEIN, UNKNOWN FUNCTION
3u7q:D (ALA148) to (GLY159) A. VINELANDII NITROGENASE MOFE PROTEIN AT ATOMIC RESOLUTION | MULTIPLE ROSSMANN FOLD DOMAINS, REDUCTASE, NITROGEN FIXING, OXIDOREDUCTASE
3hdj:B (MSE1) to (ALA12) THE CRYSTAL STRUCTURE OF PROBABLE ORNITHINE CYCLODEAMINASE FROM BORDETELLA PERTUSSIS TOHAMA I | APC62486, ORNITHINE CYCLODEAMINASE, BORDETELLA PERTUSSIS TOHAMA I, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
2uxz:B (ASN183) to (GLY194) TWO-CARBON-ELONGATED HIV-1 PROTEASE INHIBITORS WITH A TERTIARY-ALCOHOL-CONTAINING TRANSITION-STATE MIMIC | HIV-1, PROTEASE, HYDROLASE, INHIBITOR, ASPARTYL PROTEASE
2uy0:A (ASN83) to (GLY94) TWO-CARBON-ELONGATED HIV-1 PROTEASE INHIBITORS WITH A TERTIARY-ALCOHOL-CONTAINING TRANSITION-STATE MIMIC | HIV-1, PROTEASE, HYDROLASE, INHIBITOR, ASPARTYL PROTEASE
2uyi:A (GLN20) to (SER36) CRYSTAL STRUCTURE OF KSP IN COMPLEX WITH ADP AND THIOPHENE CONTAINING INHIBITOR 33 | KSP, EG5, COMPLEX, MITOSIS, THIOPHENE, INHIBITOR, NUCLEOTIDE-BINDING, KINESIN SPINDLE PROTEIN, MOTOR PROTEIN, CELL DIVISION, PHOSPHORYLATION, CELL CYCLE, MICROTUBULE, COILED COIL, ATP-BINDING
1fep:A (GLY27) to (ASN39) FERRIC ENTEROBACTIN RECEPTOR | OUTER MEMBRANE, IRON TRANSPORT, TRANSPORT, TONB, SIGNAL, RECEPTOR, MEMBRANE PROTEIN
1ff0:C (ASN83) to (GLY94) STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES. | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3hfj:A (GLY81) to (LYS95) BACILLUS ANTHRACIS NICOTINATE MONONUCLEOTIDE ADENYLYTRANSFERASE (NADD) IN COMPLEX WITH INHIBITOR CID 3289443 | ENZYME-INHIBITOR COMPLEX, NAD, NUCLEOTIDYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS, TRANSFERASE
1fff:D (ASN183) to (GLY194) STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE : HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES. | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ffi:D (ASN183) to (GLY194) STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1r43:A (LEU359) to (PHE383) CRYSTAL STRUCTURE OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI (SELENOMETHIONINE SUBSTITUTED PROTEIN) | ALPHA AND BETA PROTEIN, ONE DI-ZINC CENTER PER SUBUNIT, HYDROLASE
1r43:B (LEU359) to (GLN382) CRYSTAL STRUCTURE OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI (SELENOMETHIONINE SUBSTITUTED PROTEIN) | ALPHA AND BETA PROTEIN, ONE DI-ZINC CENTER PER SUBUNIT, HYDROLASE
4yms:J (VAL215) to (ILE239) CRYSTAL STRUCTURE OF AN AMINO ACID ABC TRANSPORTER | ABC TRANSPORTER, TWO BINDING SITES, SUBSTRATE SPECIFICITY, MEMBRANE PROTEIN COMPLEX, PROTEIN BINDING-TRANSPORT PROTEIN COMPLEX
2uzy:A (SER221) to (LYS230) STRUCTURE OF THE HUMAN RECEPTOR TYROSINE KINASE MET IN COMPLEX WITH THE LISTERIA MONOCYTOGENES INVASION PROTEIN INLB: LOW RESOLUTION, CRYSTAL FORM II | SIGNALING PROTEIN/RECEPTOR, LEUCINE RICH REPEAT, RECEPTOR ECTODOMAIN, HEPATOCYTE GROWTH FACTOR RECEPTOR, ATP-BINDING, TRANSFERASE, POLYMORPHISM, GLYCOPROTEIN, VIRULENCE FACTOR, DISEASE MUTATION, NUCLEOTIDE-BINDING, TRANSMEMBRANE, PROTO-ONCOGENE, PHOSPHORYLATION, LEUCINE-RICH REPEAT, ALTERNATIVE SPLICING, TYROSINE-PROTEIN KINASE, CHROMOSOMAL REARRANGEMENT, LRR, HGFR, KINASE, MEMBRANE, RECEPTOR, INTERNALIN, SIGNALING PROTEIN/RECEPTOR COMPLEX
2uzy:C (SER221) to (LYS230) STRUCTURE OF THE HUMAN RECEPTOR TYROSINE KINASE MET IN COMPLEX WITH THE LISTERIA MONOCYTOGENES INVASION PROTEIN INLB: LOW RESOLUTION, CRYSTAL FORM II | SIGNALING PROTEIN/RECEPTOR, LEUCINE RICH REPEAT, RECEPTOR ECTODOMAIN, HEPATOCYTE GROWTH FACTOR RECEPTOR, ATP-BINDING, TRANSFERASE, POLYMORPHISM, GLYCOPROTEIN, VIRULENCE FACTOR, DISEASE MUTATION, NUCLEOTIDE-BINDING, TRANSMEMBRANE, PROTO-ONCOGENE, PHOSPHORYLATION, LEUCINE-RICH REPEAT, ALTERNATIVE SPLICING, TYROSINE-PROTEIN KINASE, CHROMOSOMAL REARRANGEMENT, LRR, HGFR, KINASE, MEMBRANE, RECEPTOR, INTERNALIN, SIGNALING PROTEIN/RECEPTOR COMPLEX
2ejt:A (PRO319) to (LEU331) COMPLEX STRUCTURE OF TRM1 FROM PYROCOCCUS HORIKOSHII WITH S-ADENOSYL- L-METHIONINE | TRNA MODIFICATION ENZYME, GUANINE-26,N(2)-N(2)-DIMETHYLTRANSFERASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, TRANSFERASE
1fg6:D (ASN183) to (GLY194) STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1fgc:D (ASN183) to (GLY194) STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3hh1:C (GLU41) to (GLY54) THE STRUCTURE OF A TETRAPYRROLE METHYLASE FAMILY PROTEIN DOMAIN FROM CHLOROBIUM TEPIDUM TLS | TETRAPYRROLE METHYLASE, CHLOROBIUM TEPIDUM, STRUCTURAL GENOMICS, PSI- 2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, METHYLTRANSFERASE, TRANSFERASE
4yoc:A (LYS891) to (ILE907) CRYSTAL STRUCTURE OF HUMAN DNMT1 AND USP7/HAUSP COMPLEX | DNA METHYLATION, DEUBIQUITINATION, DNA METHYLTRANSFERASE, MODIFICATION, TRANSFERASE-HYDROLASE COMPLEX
3hhm:A (SER482) to (PHE506) CRYSTAL STRUCTURE OF P110ALPHA H1047R MUTANT IN COMPLEX WITH NISH2 OF P85ALPHA AND THE DRUG WORTMANNIN | P110, P85, PI3KCA, PI3K, PIK3R1, PHOSPHATIDILYNOSITOL 3,4,5- TRIPHOSPHATE, WORTMANNIN, H1047R, ATP-BINDING, DISEASE MUTATION, KINASE, NUCLEOTIDE-BINDING, ONCOGENE, POLYMORPHISM, TRANSFERASE, TRANSFERASE/ONCOPROTEIN COMPLEX
1r6c:X (ASP77) to (SER98) HIGH RESOLUTION STRUCTURE OF CLPN | CLPA, AAA+, N-TERMINAL DOMAIN, CLPS, CRYSTAL, BINDING MECHANISM, HYDROLASE
2eq5:A (ILE95) to (TYR111) CRYSTAL STRUCTURE OF HYDANTOIN RACEMASE FROM PYROCOCCUS HORIKOSHII OT3 | RACEMASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, ISOMERASE
2eq5:C (ILE95) to (GLY112) CRYSTAL STRUCTURE OF HYDANTOIN RACEMASE FROM PYROCOCCUS HORIKOSHII OT3 | RACEMASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, ISOMERASE
3ucm:B (LYS96) to (VAL114) COCCOMYXA BETA-CARBONIC ANHYDRASE IN COMPLEX WITH THIOCYANATE | ALPHA/BETA, STRAND EXCHANGE, LYASE-LYASE INHIBITOR COMPLEX
4k2j:I (TYR1014) to (GLY1043) DECAMERIC RING STRUCTURE OF KSHV (HHV-8) LATENCY-ASSOCIATED NUCLEAR ANTIGEN (LANA) DNA BINDING DOMAIN | DNA BINDING, DNA BINDING PROTEIN, VIRAL PROTEIN
2v43:A (ALA187) to (LYS203) CRYSTAL STRUCTURE OF RSEB: A SENSOR FOR PERIPLASMIC STRESS RESPONSE IN E. COLI | SENSOR FOR PERIPLASMIC STRESS, REGULATOR, REGULATORY PROTEIN, LIPOPROTEIN BINDING
4k4q:A (ASN83) to (GLY94) TL-3 INHIBITED TRP6ALA HIV PROTEASE WITH 3-BROMO-2,6-DIMETHOXYBENZOIC ACID BOUND IN FLAP SITE | FRAGMENT BINDING, EXOSITE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1rab:A (VAL122) to (GLY150) CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | TRANSFERASE
1rae:A (VAL122) to (ILE145) CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | TRANSFERASE
1rah:A (VAL122) to (GLY150) CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | TRANSFERASE
1rai:A (VAL122) to (GLY150) CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | TRANSFERASE
1fp4:B (ALA67) to (LEU80) CRYSTAL STRUCTURE OF THE ALPHA-H195Q MUTANT OF NITROGENASE | IRON-SULFUR-MOLYBDENUM PROTEIN, OXIDOREDUCTASE
1fp4:D (ALA67) to (LEU80) CRYSTAL STRUCTURE OF THE ALPHA-H195Q MUTANT OF NITROGENASE | IRON-SULFUR-MOLYBDENUM PROTEIN, OXIDOREDUCTASE
2exl:A (LYS75) to (ASN91) GRP94 N-TERMINAL DOMAIN BOUND TO GELDANAMYCIN | GRP94, GP96, HSP90, BERGERAT FOLD, CHAPERONE, ENDOPLASMIC RETICULUM, GELDANAMYCIN, 17-AAG
2exl:B (LYS75) to (LEU93) GRP94 N-TERMINAL DOMAIN BOUND TO GELDANAMYCIN | GRP94, GP96, HSP90, BERGERAT FOLD, CHAPERONE, ENDOPLASMIC RETICULUM, GELDANAMYCIN, 17-AAG
4yts:D (GLY60) to (ASP74) CRYSTAL STRUCTURE OF D-TAGATOSE 3-EPIMERASE C66S FROM PSEUDOMONAS CICHORII IN COMPLEX WITH 1-DEOXY 3-KETO D-GALACTITOL | EPIMERASE, ISOMERASE
4ytt:D (GLY60) to (ASP74) CRYSTAL STRUCTURE OF D-TAGATOSE 3-EPIMERASE C66S FROM PSEUDOMONAS CICHORII IN COMPLEX WITH 6-DEOXY L-PSICOSE | EPIMERASE, ISOMERASE
3uj4:A (GLU428) to (GLY463) CRYSTAL STRUCTURE OF THE APO-INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR | INOSITOL 1,4,5-TRISPHOSPHATE, APO-STATE, SUPPRESSOR DOMAIN, IP3- BINDING CORE DOMAIN, SIGNALING PROTEIN
4yu9:B (ASP242) to (GLY282) CRYSTAL STRUCTURE OF DOUBLE MUTANT Y115E Y117E HUMAN GLUTAMINYL CYCLASE | ALZHEIMER DISEASE, DRUG TARGET, TRANSFERASE
1rfu:C (GLY54) to (HIS73) CRYSTAL STRUCTURE OF PYRIDOXAL KINASE COMPLEXED WITH ADP AND PLP | TRANSFERASE
1rfu:D (GLY54) to (HIS73) CRYSTAL STRUCTURE OF PYRIDOXAL KINASE COMPLEXED WITH ADP AND PLP | TRANSFERASE
1rfu:E (GLY54) to (HIS73) CRYSTAL STRUCTURE OF PYRIDOXAL KINASE COMPLEXED WITH ADP AND PLP | TRANSFERASE
1rfu:G (GLY54) to (HIS73) CRYSTAL STRUCTURE OF PYRIDOXAL KINASE COMPLEXED WITH ADP AND PLP | TRANSFERASE
1rfu:H (GLY54) to (HIS73) CRYSTAL STRUCTURE OF PYRIDOXAL KINASE COMPLEXED WITH ADP AND PLP | TRANSFERASE
2v8z:B (ALA288) to (LYS307) CRYSTAL STRUCTURE OF YAGE, A PROPHAGE PROTEIN BELONGING TO THE DIHYDRODIPICOLINIC ACID SYNTHASE FAMILY FROM E. COLI K12 | LYASE, N-ACETYL NEURAMINATE LYASE, NAL, DHDPS
1rg9:A (HIS3) to (ASP34) S-ADENOSYLMETHIONINE SYNTHETASE COMPLEXED WITH SAM AND PPNP | S-ADENOSYLMETHIONINE SYNTHETASE; METHIONINE ADENOSYLTRANSFERASE
1rg9:B (HIS3) to (ASP34) S-ADENOSYLMETHIONINE SYNTHETASE COMPLEXED WITH SAM AND PPNP | S-ADENOSYLMETHIONINE SYNTHETASE; METHIONINE ADENOSYLTRANSFERASE
1rg9:C (HIS3) to (ASP34) S-ADENOSYLMETHIONINE SYNTHETASE COMPLEXED WITH SAM AND PPNP | S-ADENOSYLMETHIONINE SYNTHETASE; METHIONINE ADENOSYLTRANSFERASE
1rg9:D (HIS3) to (ASP34) S-ADENOSYLMETHIONINE SYNTHETASE COMPLEXED WITH SAM AND PPNP | S-ADENOSYLMETHIONINE SYNTHETASE; METHIONINE ADENOSYLTRANSFERASE
2f1b:A (ASP42) to (ARG51) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH (2R,3R,4S,5R)-2-({[(1R)-2- HYDROXY-1-PHENYLETHYL]AMINO}METHYL)-5-METHYLPYRROLIDINE-3,4-DIOL | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
4yve:B (ASP252) to (GLY274) ROCK 1 BOUND TO METHOXYPHENYL THIAZOLE INHIBITOR | KINASE, DIMER, DIMERIZATION, MYOSIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4yw9:A (MET173) to (GLY185) STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH 3-MERCAPTOPICOLINIC ACID AND GTP | KINASE, GLUCONEOGENESIS, LYASE, TRANSFERASE
4ywb:A (MET173) to (GLY185) STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH 3-MERCAPTOPICOLINIC ACID AND OXALIC ACID | KINASE, GLUCONEOGENESIS, LYASE
1rl8:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF THE COMPLEX OF RESISTANT STRAIN OF HIV-1 PROTEASE(V82A MUTANT) WITH RITONAVIR | ASPARTIC PROTEASE, ASPARTIC PROTEASE-INHIBITOR COMPLEX, RESISTANT STRAIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ywy:A (ASP242) to (GLY282) CRYSTAL STRUCTURE OF DOUBLE MUTANT Y115E Y117E HUMAN GLUTAMINYL CYCLASE IN COMPLEX WITH INHIBITOR PBD-150 | ALZHEIMER DISEASE, CYCLOTRANSFERASE SOLUBLE VARIANT, PBD-150 INHIBITOR, TRANSFERASE
4ywy:B (LEU243) to (GLY282) CRYSTAL STRUCTURE OF DOUBLE MUTANT Y115E Y117E HUMAN GLUTAMINYL CYCLASE IN COMPLEX WITH INHIBITOR PBD-150 | ALZHEIMER DISEASE, CYCLOTRANSFERASE SOLUBLE VARIANT, PBD-150 INHIBITOR, TRANSFERASE
4ywy:C (LEU243) to (GLY282) CRYSTAL STRUCTURE OF DOUBLE MUTANT Y115E Y117E HUMAN GLUTAMINYL CYCLASE IN COMPLEX WITH INHIBITOR PBD-150 | ALZHEIMER DISEASE, CYCLOTRANSFERASE SOLUBLE VARIANT, PBD-150 INHIBITOR, TRANSFERASE
4yxk:L (ALA109) to (GLY128) CRYSTAL STRUCTURE OF ELK PRION PROTEIN COMPLEXED WITH POM1 FAB | PRION, ANTIBODY, IMMUNE SYSTEM COMPLEX, IMMUNE SYSTEM
4kb9:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE WITH NOVEL TRICYCLIC P2- LIGANDS GRL-0739A | SPARTIC ACID PROTEASE, HIV-1 PROTEASE INHIBITOR GRL-0739A, A NOVEL TRICYCLIC P2-LIGAND,, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1fy7:A (ILE402) to (ALA418) CRYSTAL STRUCTURE OF YEAST ESA1 HISTONE ACETYLTRANSFERASE DOMAIN COMPLEXED WITH COENZYME A | HISTONE ACETYLTRANSFERASE, COENZYME A, TRANSFERASE
1fyz:A (PHE359) to (ASN375) METHANE MONOOXYGENASE HYDROXYLASE, FORM II REDUCED BY SOAKING | DINUCLEAR IRON CENTER, MONOOXYGENASE, OXIDOREDUCTASE
1fz0:A (PHE359) to (ASN375) METHANE MONOOXYGENASE HYDROXYLASE, FORM II MIXED-VALENT GROWN ANAEROBICALLY | DINUCLEAR IRON CENTER, MONOOXYGENASE, OXIDOREDUCTASE
1fz2:A (PHE359) to (ASN375) METHANE MONOOXYGENASE HYDROXYLASE, FORM II MIXED-VALENT GENERATED BY CRYSTAL SOAKING | DINUCLEAR IRON CENTER, MONOOXYGENASE, OXIDOREDUCTASE
1fz3:A (PHE359) to (ASN375) METHANE MONOOXYGENASE HYDROXYLASE, FORM III SOAK AT PH 6.2 (0.1 M PIPES) | DINUCLEAR IRON CENTER, MONOOXYGENASE, OXIDOREDUCTASE
1rq9:B (ASN83) to (GLY94) CRYSTAL STRUCTURES OF A MULTIDRUG-RESISTANT HIV-1 PROTEASE REVEAL AN EXPANDED ACTIVE SITE CAVITY | HIV PROTEASE, AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, MULTI-DRUG RESISTANCE
1fz4:B (PHE359) to (ASN375) METHANE MONOOXYGENASE HYDROXYLASE, FORM III SOAKED AT PH 8.5 (0.1 M TRIS) | DINUCLEAR IRON CENTER, MONOOXYGENASE, OXIDOREDUCTASE
2f81:B (ASN183) to (GLY194) HIV-1 PROTEASE MUTANT L90M COMPLEXED WITH INHIBITOR TMC114 | HIV-1 PROTEASE-INHIBITOR COMPLEX, HYDROLASE
1fzd:A (ASN763) to (GLY785) STRUCTURE OF RECOMBINANT ALPHAEC DOMAIN FROM HUMAN FIBRINOGEN-420 | BLOOD COAGULATION, FIBRINOGEN-420, ALPHAEC DOMAIN, FIBRINOGEN RELATED DOMAIN, GLYCOSYLATED PROTEIN
1fze:C (GLU225) to (GLN239) CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN | BLOOD COAGULATION, PLASMA, PLATELET, FIBRINOGEN, FIBRIN
2f8g:B (ASN183) to (GLY194) HIV-1 PROTEASE MUTANT I50V COMPLEXED WITH INHIBITOR TMC114 | HIV-1 PROTEASE-INHIBITOR COMPLEX, HYDROLASE
1fzt:A (ASN8) to (ASN24) SOLUTION STRUCTURE AND DYNAMICS OF AN OPEN B-SHEET, GLYCOLYTIC ENZYME-MONOMERIC 23.7 KDA PHOSPHOGLYCERATE MUTASE FROM SCHIZOSACCHAROMYCES POMBE | OPEN B-SHEET-HELICES, ISOMERASE
2faf:A (MET193) to (LEU204) THE STRUCTURE OF CHICKEN MITOCHONDRIAL PEPCK. | PHOSPHOENOLPYRUVATE CARBOXYKINASE, PEPCK, KINASE, PHOSPHORYL TRANSFER, LYASE
3une:d (LYS222) to (ARG249) MOUSE CONSTITUTIVE 20S PROTEASOME | 20S PROTEASOME COMPRISES 28 SUBUNITS, PROTEASE, CYTOSOL, HYDROLASE
2fah:B (MET193) to (LEU204) THE STRUCTURE OF MITOCHONDRIAL PEPCK, COMPLEX WITH MN AND GDP | PHOSPHOENOLPYRUVATE CARBOXYKINASE, PEPCK, PCK, PEP,GDP, KINASE, PHOSPHORYL TRANSFER, LYASE
1g21:B (ASP145) to (GLY159) MGATP-BOUND AND NUCLEOTIDE-FREE STRUCTURES OF A NITROGENASE PROTEIN COMPLEX BETWEEN LEU127DEL-FE PROTEIN AND THE MOFE PROTEIN | NITROGEN-FIXATION, FE PROTEIN, MOEFE PROTEIN, P-CLUSTER, FEMO COFACTOR, 4FE-4S, OXIDOREDUCTASE
1g2k:B (ASN83) to (GLY94) HIV-1 PROTEASE WITH CYCLIC SULFAMIDE INHIBITOR, AHA047 | HIV, PROTEASE INHIBITORS, HYDROLASE
1g35:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR, AHA024 | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
1rv8:A (PRO43) to (TYR55) CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE FROM THERMUS AQUATICUS IN COMPLEX WITH COBALT | CLASS II ALDOLASE, METAL-DEPDENDENT ALDOLASE, LYASE
1rvg:A (PRO43) to (TYR55) CRYSTAL STRCUTURE OF CLASS II FRUCTOSE-BISPHOSPHATE ALDOLASE FROM THERMUS AQUATICUS IN COMPLEX WITH Y | CLASS II ALDOLASE, METAL-DEPDENDENT ALDOLASE, LYASE
1rvg:B (PRO43) to (GLY57) CRYSTAL STRCUTURE OF CLASS II FRUCTOSE-BISPHOSPHATE ALDOLASE FROM THERMUS AQUATICUS IN COMPLEX WITH Y | CLASS II ALDOLASE, METAL-DEPDENDENT ALDOLASE, LYASE
4kgv:A (VAL122) to (THR148) THE R STATE STRUCTURE OF E. COLI ATCASE WITH ATP BOUND | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, COMPETING PATHWAY, PRODUCT ACTIVATION, ALLOSTERY, TRANSFERASE
4kgv:C (VAL122) to (THR148) THE R STATE STRUCTURE OF E. COLI ATCASE WITH ATP BOUND | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, COMPETING PATHWAY, PRODUCT ACTIVATION, ALLOSTERY, TRANSFERASE
4kgz:C (VAL122) to (THR148) THE R STATE STRUCTURE OF E. COLI ATCASE WITH UTP AND MAGNESIUM BOUND | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, COMPETING PATHWAY PRODUCT ACTIVATION, ALLOSTERY, TRANSFERASE
2ve4:A (ASN139) to (PHE159) SUBSTRATE FREE CYANOBACTERIAL CYP120A1 | OXIDOREDUCTASE, MONOOXYGENASE, METAL-BINDING, HEME, IRON
4kh0:A (VAL122) to (THR148) THE R STATE STRUCTURE OF E. COLI ATCASE WITH ATP AND MAGNESIUM BOUND | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, COMPETING PATHWAY PRODUCT ACTIVATION, ALLOSTERY, TRANSFERASE
4kh0:C (PRO123) to (THR148) THE R STATE STRUCTURE OF E. COLI ATCASE WITH ATP AND MAGNESIUM BOUND | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, COMPETING PATHWAY PRODUCT ACTIVATION, ALLOSTERY, TRANSFERASE
1g6l:A (ASN83) to (GLY94) 1.9A CRYSTAL STRUCTURE OF TETHERED HIV-1 PROTEASE | HYDROLASE
2fgu:A (ASN83) to (GLY94) X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE T80S VARIANT IN COMPLEX WITH THE INHIBITOR SAQUINAVIR USED TO EXPLORE THE ROLE OF INVARIANT THR80 IN HIV-1 PROTEASE STRUCTURE, FUNCTION, AND VIRAL INFECTIVITY. | HIV PROTEASE, DRUG RESISTANCE, ENZYME KINETICS, SEQUENCE CONSERVATION, PROTEIN STRUCTURE, HYDROLASE
4z44:A (VAL47) to (GLN56) F454K MUTANT OF TRYPTOPHAN 7-HALOGENASE PRNA | OXIDOREDUCTASE
3hoz:E (SER59) to (PHE72) COMPLETE RNA POLYMERASE II ELONGATION COMPLEX IV WITH A T-U MISMATCH AND A FRAYED RNA 3'-GUANINE | RNA-FRAYING, RNA POLYMERASE II, METAL BINDING, TRANSCRIPTION BUBBLE, ELONGATION COMPLEX, TRANSCRIPTION, DNA-RNA MISMATCH, RNA FRAYING, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, MRNA PROCESSING, TRANSCRIPTION,TRANSFERASE/DNA/RNA HYBRID COMPLEX
3hq1:B (PRO162) to (ARG182) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS LEUA COMPLEXED WITH CITRATE AND MN2+ | 2-ISOPROPYLMALATE SYNTHASE, LEUA, MYCOBACTERIUM TUBERCULOSIS, INHIBITION, BROMOPYRUVATE, AMINO-ACID BIOSYNTHESIS, BRANCHED-CHAIN AMINO ACID BIOSYNTHESIS, LEUCINE BIOSYNTHESIS, TRANSFERASE
1ga1:A (GLY354) to (SER367) CRYSTAL STRUCTURE ANALYSIS OF PSCP (PSEUDOMONAS SERINE-CARBOXYL PROTEINASE) COMPLEXED WITH A FRAGMENT OF IODOTYROSTATIN (THIS ENZYME RENAMED "SEDOLISIN" IN 2003) | SERINE-CARBOXYL PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ga4:A (GLY354) to (SER367) CRYSTAL STRUCTURE ANALYSIS OF PSCP (PSEUDOMONAS SERINE-CARBOXYL PROTEINASE) COMPLEXED WITH INHIBITOR PSEUDOIODOTYROSTATIN (THIS ENZYME RENAMED "SEDOLISIN" IN 2003) | SERINE-CARBOXYL PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2fky:A (GLN20) to (SER36) CRYSTAL STRUCTURE OF KSP IN COMPLEX WITH INHIBITOR 13 | KSP, KSP-INHIBITOR COMPLEX, CELL CYCLE
2fky:B (ILE19) to (SER36) CRYSTAL STRUCTURE OF KSP IN COMPLEX WITH INHIBITOR 13 | KSP, KSP-INHIBITOR COMPLEX, CELL CYCLE
2fl6:B (ASN18) to (SER36) CRYSTAL STRUCTURE OF KSP IN COMPLEX WITH INHIBITOR 6 | KSP, KSP-INHIBITOR COMPLEX, CELL CYCLE
2fle:A (ASN83) to (GLY94) STRUCTURAL ANALYSIS OF ASYMMETRIC INHIBITOR BOUND TO THE HIV-1 PROTEASE V82A MUTANT | HIV-1 PROTEASE, INHIBITOR, RESISTANCE, INDUCED FIT, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
1s3s:F (LEU445) to (SER457) CRYSTAL STRUCTURE OF AAA ATPASE P97/VCP ND1 IN COMPLEX WITH P47 C | AAA ATPASE, P97, P47, PROTEIN-PROTEIN COMPLEX, UBX DOMAIN, PROTEIN BINDING
4z9w:A (MET178) to (ASN193) STRUCTURAL STUDIES ON A NON-TOXIC HOMOLOGUE OF TYPE II RIPS FROM MOMORDICA CHARANTIA (BITTER GOURD)-NATIVE-2 | BETA-TREFOIL, TYPE II RIPS, GALACTOSE BINDING LECTIN, HYDROLASE
2fok:A (HIS263) to (GLY280) STRUCTURE OF RESTRICTION ENDONUCLEASE FOKI | NUCLEIC ACID RECOGNITION, DNA-BINDING PROTEIN, TYPE IIS RESTRICTION ENDONUCLEASE, DEOXYRIBONUCLEASE, DNA HYDROLYSIS, DNA CLEAVAGE, METALLOENZYME, METAL ION CATALYSIS
2fok:B (HIS263) to (GLY280) STRUCTURE OF RESTRICTION ENDONUCLEASE FOKI | NUCLEIC ACID RECOGNITION, DNA-BINDING PROTEIN, TYPE IIS RESTRICTION ENDONUCLEASE, DEOXYRIBONUCLEASE, DNA HYDROLYSIS, DNA CLEAVAGE, METALLOENZYME, METAL ION CATALYSIS
1s4f:D (LYS603) to (GLY621) CRYSTAL STRUCTURE OF RNA-DEPENDENT RNA POLYMERASE CONSTRUCT 2 FROM BOVINE VIRAL DIARRHEA VIRUS (BVDV) | POLYMERASE, RNA SYNTHESIS, PRIMER INDEPENDENT INITIATION, DE NOVO INITIATION, BOVINE VIRAL DIARRHEA VIRUS, BVDV, REPLICATION, RNA BINDING PROTEIN
1ggt:B (LEU580) to (LEU598) THREE-DIMENSIONAL STRUCTURE OF A TRANSGLUTAMINASE: HUMAN BLOOD COAGULATION FACTOR XIII | BLOOD COAGULATION
1s78:E (THR109) to (GLY128) INSIGHTS INTO ERBB SIGNALING FROM THE STRUCTURE OF THE ERBB2- PERTUZUMAB COMPLEX | RECEPTOR-ANTIBODY COMPLEX, FAB FRAGMENT, CYSTEINE-RICH DOMAIN, LEUCINE-RICH REPEAT, TRANSFERASE
1sb6:A (MET1) to (CYS12) SOLUTION STRUCTURE OF A CYANOBACTERIAL COPPER METALLOCHAPERONE, SCATX1 | COPPER CHAPERONE, NEW METAL BINDING MOTIF, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, STRUCTURAL GENOMICS, CHAPERONE
1sdt:A (ASN83) to (GLY94) CRYSTAL STRUCTURES OF HIV PROTEASE V82A AND L90M MUTANTS REVEAL CHANGES IN INDINAVIR BINDING SITE. | DRUG RESISTANCE; HIV-1, HYDROLASE
1sdu:A (ASN83) to (GLY94) CRYSTAL STRUCTURES OF HIV PROTEASE V82A AND L90M MUTANTS REVEAL CHANGES IN INDINAVIR BINDING SITE. | DRUG RESISTANCE HIV-1 PROTEASE, HYDROLASE
1sdu:B (ASN183) to (GLY194) CRYSTAL STRUCTURES OF HIV PROTEASE V82A AND L90M MUTANTS REVEAL CHANGES IN INDINAVIR BINDING SITE. | DRUG RESISTANCE HIV-1 PROTEASE, HYDROLASE
1sdv:A (ASN83) to (GLY94) CRYSTAL STRUCTURES OF HIV PROTEASE V82A AND L90M MUTANTS REVEAL CHANGES IN INDINAVIR BINDING SITE. | DRUG RESISTANCE; HIV-1 PROTEASE, HYDROLASE
4zfn:A (GLU3) to (ASN27) HYPOXANTHINE-GUANINE-XANTHINE PHOSPHORIBOSYLTRANSFERASE (HGXPRT) FROM SULFOLOBUS SOLFATARICUS CONTAINING GMP COMPLEXED IN TWO DIFFERENT WAYS TOGETHER WITH ONE OR TWO MG2+ | TRANSFERASE, HGXPRT, HGPRT, PURINE PHOSPHORIBOSYLTRANSFERASE
1ses:B (ALA381) to (ASN394) CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE | LIGASE, SYNTHETASE
1set:B (ALA381) to (ASN394) CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE | LIGASE, SYNTHETASE
2fxe:A (ASN83) to (GLY94) X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE CRM MUTANT COMPLEXED WITH ATAZANAVIR (BMS-232632) | HUMAN IMMUNODEFICIENCY VIRUS (HIV), HIV-1 PROTEASE, REYATAZ, ATAZANAVIR, BMS-232632, HYDROLASE
3v67:A (PRO41) to (SER67) PERIPLASMIC DOMAIN OF VIBRIO PARAHAEMOLYTICUS CPXA | PAS FOLD, SIGNAL SENSING, SIGNALING PROTEIN, MEROHEDRAL TWINNING
1gno:B (ASN83) to (GLY94) HIV-1 PROTEASE (WILD TYPE) COMPLEXED WITH U89360E (INHIBITOR) | ASPARTIC PROTEASE, HIV, MUTANT, INHIBITOR, U-89360E, HYDROLASE (ACID PROTEASE)
3i01:M (ILE425) to (LYS437) NATIVE STRUCTURE OF BIFUNCTIONAL CARBON MONOXIDE DEHYDROGENASE/ACETYL- COA SYNTHASE FROM MOORELLA THERMOACETICA, WATER-BOUND C-CLUSTER. | PROTEIN-PROTEIN COMPLEX, CARBON DIOXIDE FIXATION, ELECTRON TRANSPORT, IRON, IRON-SULFUR, METAL-BINDING, NICKEL, OXIDOREDUCTASE, TRANSPORT, TRANSFERASE, OXIDOREDUCTASE-TRANSFERASE COMPLEX
2g0w:A (GLN168) to (ASN180) CRYSTAL STRUCTURE OF A PUTATIVE SUGAR ISOMERASE (LMO2234) FROM LISTERIA MONOCYTOGENES AT 1.70 A RESOLUTION | PUTATIVE SUGAR ISOMERASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, HYDROLASE
1sio:B (GLY344) to (LEU356) STRUCTURE OF KUMAMOLISIN-AS COMPLEXED WITH A COVALENTLY-BOUND INHIBITOR, ACIPF | KUMAMOLISIN-AS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3v8c:B (GLN342) to (ASN361) CRYSTAL STRUCTURE OF MONOCLONAL HUMAN ANTI-RHESUS D FC IGG1 T125(YB2/0) DOUBLE MUTANT (H310 AND H435 IN K) | FC IGG1, FC-GAMMA RECEPTOR, IMMUNE SYSTEM
3v8x:A (GLY59) to (GLN72) THE CRYSTAL STRUCTURE OF TRANSFERRIN BINDING PROTEIN A (TBPA) FROM NEISSERIAL MENINGITIDIS SEROGROUP B IN COMPLEX WITH FULL LENGTH HUMAN TRANSFERRIN | IRON BINDING PROTEIN, TRANSFERRIN BINDING PROTEIN A, IRON BINDING/SCAVENGING, MEMBRANE PROTEIN-METAL TRANSPORT COMPLEX
3v95:A (GLN342) to (ASN361) CRYSTAL STRUCTURE OF MONOCLONAL HUMAN ANTI-RHESUS D FC AND IGG1 T125(YB2/0) IN THE PRESENCE OF EDTA | FC IGG1, FC-GAMMA RECEPTOR, IMMUNE SYSTEM
3v95:B (GLN342) to (ASN361) CRYSTAL STRUCTURE OF MONOCLONAL HUMAN ANTI-RHESUS D FC AND IGG1 T125(YB2/0) IN THE PRESENCE OF EDTA | FC IGG1, FC-GAMMA RECEPTOR, IMMUNE SYSTEM
1grl:A (VAL6) to (LEU31) THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS | CHAPERONIN
1grl:B (VAL6) to (LEU31) THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS | CHAPERONIN
1grl:C (VAL6) to (LEU31) THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS | CHAPERONIN
1grl:D (VAL6) to (LEU31) THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS | CHAPERONIN
1grl:E (VAL6) to (LEU31) THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS | CHAPERONIN
1grl:F (VAL6) to (LEU31) THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS | CHAPERONIN
1grl:G (VAL6) to (LEU31) THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS | CHAPERONIN
4ku1:A (GLN342) to (ASN361) ROLE OF THE HINGE AND C-GAMMA-2/C-GAMMA-3 INTERFACE IN IMMUNOGLOBIN G1 FC DOMAIN MOTIONS: IMPLICATIONS FOR FC ENGINEERING | HUMAN FC FRAGMENT, IMMUNE RESPONSE, IMMUNE SYSTEM
4ku1:B (GLN342) to (ASN361) ROLE OF THE HINGE AND C-GAMMA-2/C-GAMMA-3 INTERFACE IN IMMUNOGLOBIN G1 FC DOMAIN MOTIONS: IMPLICATIONS FOR FC ENGINEERING | HUMAN FC FRAGMENT, IMMUNE RESPONSE, IMMUNE SYSTEM
3vbq:A (PRO125) to (GLU135) EXPLOITATION OF HYDROGEN BONDING CONSTRAINTS AND FLAT HYDROPHOBIC ENERGY LANDSCAPES IN PIM-1 KINASE NEEDLE SCREENING AND INHIBITOR DESIGN | PIM1, ROSSMANN FOLD, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2vt2:A (ARG188) to (SER209) STRUCTURE AND FUNCTIONAL PROPERTIES OF THE BACILLUS SUBTILIS TRANSCRIPTIONAL REPRESSOR REX | TRANSCRIPTIONAL REGULATION, REDOX POISE, DNA-BINDING, TRANSCRIPTION, REPRESSOR, DNA BINDING
2vt2:B (HIS186) to (LYS206) STRUCTURE AND FUNCTIONAL PROPERTIES OF THE BACILLUS SUBTILIS TRANSCRIPTIONAL REPRESSOR REX | TRANSCRIPTIONAL REGULATION, REDOX POISE, DNA-BINDING, TRANSCRIPTION, REPRESSOR, DNA BINDING
2vt3:A (ARG188) to (SER209) STRUCTURE AND FUNCTIONAL PROPERTIES OF THE BACILLUS SUBTILIS TRANSCRIPTIONAL REPRESSOR REX | TRANSCRIPTIONAL REGULATION, REDOX POISE, TRANSCRIPTION
3i4m:E (SER59) to (PRO73) 8-OXOGUANINE CONTAINING RNA POLYMERASE II ELONGATION COMPLEX D | RNA POLYMERASE II, METAL-BINDING, TRANSCRIPTION BUBBLE, ELONGATION COMPLEX, TRANSCRIPTION, 8-OXOGUANINE, OXIDATIVE DAMAGE, DNA DAMAGE, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, ZINC-FINGER, DNA REPAIR, MRNA PROCESSING, TRANSCRIPTION,TRANSFERASE-DNA-RNA HYBRID COMPLEX
4zip:B (ASN83) to (GLY94) HIV-1 WILD TYPE PROTEASE WITH GRL-0648A (A ISOPHTHALAMIDE-DERIVED P2- LIGAND) | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1sp5:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH A PRODUCT OF AUTOPROTEOLYSIS | PRODUCT, PEPTIDE, AUTOPROTEOLYSIS, SELF-DIGESTION, AUTODIGESTION, ASPARTIC PROTEASE, HIV, PROTEASE, COMPLEX(ASPARTIC PROTEASE/PEPTIDE), HYDROLASE
1gt9:2 (GLY344) to (LEU356) HIGH RESOLUTION CRYSTAL STRUCTURE OF A THERMOSTABLE SERINE-CARBOXYL TYPE PROTEINASE, KUMAMOLISIN (KSCP) | HYDROLASE, SERINE-CARBOXYL TYPE PROTEINASE, THERMOSTABLE
1gte:D (TYR762) to (ARG771) DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, BINARY COMPLEX WITH 5-IODOURACIL | ELECTRON TRANSFER, FLAVIN, IRON-SULFUR CLUSTERS, PYRIMIDINE CATABOLISM, 5-FLUOROURACIL DEGRADATION, OXIDOREDUCTASE
1gth:A (TYR762) to (ARG771) DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX WITH NADPH AND 5-IODOURACIL | ELECTRON TRANSFER, FLAVIN, IRON-SULFUR CLUSTERS, PYRIMIDINE CATABOLISM, 5-FLUOROURACIL DEGRADATION, OXIDOREDUCTASE
1gth:C (TYR762) to (ARG771) DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX WITH NADPH AND 5-IODOURACIL | ELECTRON TRANSFER, FLAVIN, IRON-SULFUR CLUSTERS, PYRIMIDINE CATABOLISM, 5-FLUOROURACIL DEGRADATION, OXIDOREDUCTASE
1gth:D (TYR762) to (ARG771) DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX WITH NADPH AND 5-IODOURACIL | ELECTRON TRANSFER, FLAVIN, IRON-SULFUR CLUSTERS, PYRIMIDINE CATABOLISM, 5-FLUOROURACIL DEGRADATION, OXIDOREDUCTASE
4kwv:A (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN APO-QPRT | NAD, METABOLISM, TYPE II PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, PRPP, BRAIN, TRANSFERASE
4kwv:B (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN APO-QPRT | NAD, METABOLISM, TYPE II PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, PRPP, BRAIN, TRANSFERASE
4kwv:C (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN APO-QPRT | NAD, METABOLISM, TYPE II PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, PRPP, BRAIN, TRANSFERASE
4kwv:D (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN APO-QPRT | NAD, METABOLISM, TYPE II PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, PRPP, BRAIN, TRANSFERASE
4kwv:E (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN APO-QPRT | NAD, METABOLISM, TYPE II PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, PRPP, BRAIN, TRANSFERASE
4kwv:F (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN APO-QPRT | NAD, METABOLISM, TYPE II PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, PRPP, BRAIN, TRANSFERASE
4kww:A (LEU167) to (GLY179) THE CRYSTAL STRUCTURE OF HUMAN QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH ITS INHIBITOR PHTHALIC ACID | NAD, METABOLISM, TYPE II PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, PRPP, BRAIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4kww:B (LEU167) to (GLY179) THE CRYSTAL STRUCTURE OF HUMAN QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH ITS INHIBITOR PHTHALIC ACID | NAD, METABOLISM, TYPE II PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, PRPP, BRAIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4kww:C (LEU167) to (ALA178) THE CRYSTAL STRUCTURE OF HUMAN QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH ITS INHIBITOR PHTHALIC ACID | NAD, METABOLISM, TYPE II PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, PRPP, BRAIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4kww:D (LEU167) to (ALA178) THE CRYSTAL STRUCTURE OF HUMAN QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH ITS INHIBITOR PHTHALIC ACID | NAD, METABOLISM, TYPE II PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, PRPP, BRAIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4kww:E (LEU167) to (GLY179) THE CRYSTAL STRUCTURE OF HUMAN QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH ITS INHIBITOR PHTHALIC ACID | NAD, METABOLISM, TYPE II PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, PRPP, BRAIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4kww:F (LEU167) to (GLY179) THE CRYSTAL STRUCTURE OF HUMAN QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH ITS INHIBITOR PHTHALIC ACID | NAD, METABOLISM, TYPE II PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, PRPP, BRAIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1sry:B (ALA381) to (ASN394) REFINED CRYSTAL STRUCTURE OF THE SERYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS AT 2.5 ANGSTROMS RESOLUTION | LIGASE(SYNTHETASE)
3i6o:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE WITH MACROCYCLIC INHIBITOR GRL-0216A | HIV-1, WILD TYPE PROTEASE, PROTEASE INHIBITOR, MACROCYCLIC LIGAND, AIDS, ASPARTYL PROTEASE, HYDROLASE
3i6o:B (ASN183) to (GLY194) CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE WITH MACROCYCLIC INHIBITOR GRL-0216A | HIV-1, WILD TYPE PROTEASE, PROTEASE INHIBITOR, MACROCYCLIC LIGAND, AIDS, ASPARTYL PROTEASE, HYDROLASE
3i7e:A (ASN83) to (GLY94) CO-CRYSTAL STRUCTURE OF HIV-1 PROTEASE BOUND TO A MUTANT RESISTANT INHIBITOR UIC-98038 | AIDS, HIV, HIV PRTEASE, HIV-PROTEASE INHIBITOR, DRUG DESIGN, ASPARTIC PROTEASE, ACID PROTEASE, STRUCTURE BASED DRUG DESIGN, ASPARTYL PROTEASE, HYDROLASE, PROTEASE
4zjh:A (ASN247) to (ALA265) CRYSTAL STRUCTURE OF NATIVE ALPHA-2-MACROGLOBULIN FROM ESCHERICHIA COLI SPANNING DOMAINS NIE-MG1. | BACTERIAL PAN-PROTEINASE INHIBITOR, MEMBRANE PROTEIN
3vdd:C (PHE83) to (THR97) STRUCTURE OF HRV2 CAPSID COMPLEXED WITH ANTIVIRAL COMPOUND BTA798 | VIRAL CAPSID, VIRUS-DRUG COMPLEX, VIRUS
4kyw:A (SER202) to (GLU213) RESTRICTION ENDONUCLEASE DPNI IN COMPLEX WITH TWO DNA MOLECULES | RESTRICTION ENDONUCLEASE-DNA COMPLEX, TYPE IIM, TYPE IIE, RESTRICTION ENZYME, DPNI, METHYLATION DEPENDENT, N6-METHYLADENINE, PD-(D/E)XK TYPE ENDONUCLEASE, WINGED HELIX DOMAIN, RESTRICTION ENDONUCLEASE, DNA BINDING, HYDROLASE-DNA COMPLEX
3i8n:A (GLY239) to (GLY253) A DOMAIN OF A CONSERVED FUNCTIONALLY KNOWN PROTEIN FROM VIBRIO PARAHAEMOLYTICUS RIMD 2210633. | APC64273.1, VIBRIO PARAHAEMOLYTICUS RIMD 2210633, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG., UNKNOWN FUNCTION
3i9m:B (GLN171) to (ALA200) CRYSTAL STRUCTURE OF HUMAN CD38 COMPLEXED WITH AN ANALOG ARA-2'F-ADPR | ENZYME-ANALOG COMPLEX, COVALENT REACTION INTERMEDIATE, ALPHA HELICES RICH DOMAIN AND ALPHA/BETA DOMAIN, ALTERNATIVE SPLICING, DIABETES MELLITUS, DISULFIDE BOND, GLYCOPROTEIN, HYDROLASE, MEMBRANE, NAD, POLYMORPHISM, RECEPTOR, SIGNAL- ANCHOR, TRANSMEMBRANE
3vec:A (SER60) to (VAL75) RHODOCOCCUS JOSTII RHA1 DYPB D153A VARIANT IN COMPLEX WITH HEME | PEROXIDASE, LIGNAN, DYP, OXIDOREDUCTASE
3vec:C (SER60) to (VAL75) RHODOCOCCUS JOSTII RHA1 DYPB D153A VARIANT IN COMPLEX WITH HEME | PEROXIDASE, LIGNAN, DYP, OXIDOREDUCTASE
3ved:C (SER60) to (VAL75) RHODOCOCCUS JOSTII RHA1 DYPB D153H VARIANT IN COMPLEX WITH HEME | PEROXIDASE, LIGNAN, DYP, OXIDOREDUCTASE
3vee:C (SER60) to (VAL75) RHODOCOCCUS JOSTII RHA1 DYPB N246A VARIANT IN COMPLEX WITH HEME | PEROXIDASE, LIGNAN, DYP, OXIDOREDUCTASE
3vef:A (SER60) to (VAL75) RHODOCOCCUS JOSTII RHA1 DYPB N246H VARIANT IN COMPLEX WITH HEME | PEROXIDASE, LIGNAN, DYP, OXIDOREDUCTASE
3vef:C (SER60) to (VAL75) RHODOCOCCUS JOSTII RHA1 DYPB N246H VARIANT IN COMPLEX WITH HEME | PEROXIDASE, LIGNAN, DYP, OXIDOREDUCTASE
1gzh:B (ALA1733) to (ALA1746) CRYSTAL STRUCTURE OF THE BRCT DOMAINS OF HUMAN 53BP1 BOUND TO THE P53 TUMOR SUPRESSOR | GENE REGULATION, ANTI-ONCOGENE, DNA-BINDING, TRANSCRIPTION REGULATION, BCRT DOMAIN, REPEAT, APOPTOSIS, DISEASE MUTATION, ACTIVATOR, DNA- REPAIR
1syo:B (ASP1166) to (CYS1190) N-TERMINAL 3 DOMAINS OF CI-MPR BOUND TO MANNOSE 6-PHOSPHATE | LECTIN; RECEPTOR; MANNOSE 6-PHOSPHATE, PROTEIN TRANSPORT,SUGAR BINDING PROTEIN
1sz0:B (ASP1166) to (CYS1190) N-TERMINAL 3 DOMAINS OF CI-MPR BOUND TO MANNOSE 6-PHOSPHATE | LECTIN; RECEPTOR; MANNOSE 6-PHOSPHATE, PROTEIN TRANSPORT,SUGAR BINDING PROTEIN
3vf5:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT I47V WITH NOVEL P1'-LIGANDS GRL-02031 | PROTEASE INHIBITOR,P1'-LIGAND, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vfa:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT V82A WITH NOVEL P1'-LIGANDS GRL-02031 | PROTEASE INHIBITOR,P1'-LIGAND, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vfa:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT V82A WITH NOVEL P1'-LIGANDS GRL-02031 | PROTEASE INHIBITOR,P1'-LIGAND, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vfb:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT N88D WITH NOVEL P1'-LIGANDS GRL-02031 | PROTEASE INHIBITOR,P1'-LIGAND, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1t11:B (VAL240) to (GLY257) TRIGGER FACTOR | HELIX-TURN-HELIX, FOUR-HELIX-BUNDLE, PPIASE, CHAPERONE
4l23:A (VAL484) to (GLU503) CRYSTAL STRUCTURE OF P110ALPHA COMPLEXED WITH NISH2 OF P85ALPHA AND PI-103 | ATP BINDING, PI-103, SIGNALING PROTEIN-TRANSFERASE-INHIBITOR COMPLEX
1t1e:A (GLY533) to (LEU545) HIGH RESOLUTION CRYSTAL STRUCTURE OF THE INTACT PRO- KUMAMOLISIN, A SEDOLISIN TYPE PROTEINASE (PREVIOUSLY CALLED KUMAMOLYSIN OR KSCP) | PROENZYME, PROSUBTILASE, ACTIVATION MECHANISM, SEDOLISIN, SERINE-CARBOXYL PROTEINASE, HYDROLASE
4l2y:A (VAL484) to (ARG502) CRYSTAL STRUCTURE OF P110ALPHA COMPLEXED WITH NISH2 OF P85ALPHA AND COMPOUND 9D | ATP BINDING, SIGNALING PROTEIN-TRANSFERASE-INHIBITOR COMPLEX
1t3l:A (GLY117) to (GLU138) STRUCTURAL ANALYSIS OF THE VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT FUNCTIONAL CORE IN COMPLEX WITH ALPHA1 INTERACTION DOMAIN | PROTEIN-PEPTIDE COMPLEX, SH3 DOMAIN, GUANYLATE KINASE DOMAIN, TRANSPORT PROTEIN
4l4j:A (GLN342) to (ASN361) CRYSTAL STRUCTURE OF FC-FRAGMENT OF HUMAN IGG2-SIGMA ANTIBODY | IMMUNOGLOBULIN FOLD, IMMUNE SYSTEM
1h3n:A (GLU124) to (GLY147) LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A SULPHAMOYL ANALOGUE OF LEUCYL-ADENYLATE | AMINOACYL-TRNA SYNTHETASE, CLASS I AMINOACYL-TRNA SYNTHETASE, ATP + L-LEUCINE + TRNA (LEU) -> AMP + PPI + L-LEUCYL-TRNA(LEU), LIGASE
4zlo:B (SER419) to (ARG438) SERINE/THREONINE-PROTEIN KINASE PAK1 COMPLEXED WITH A DIBENZODIAZEPINE: IDENTIFICATION OF AN ALLOSTERIC SITE ON PAK1 | DIBENZODAZEPINE, PAK1, KINASE, ALLOSTERIC INHIBITOR, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4zls:A (ASN83) to (GLY94) HIV-1 WILD TYPE PROTEASE WITH GRL-096-13A (A BOC-DERIVATIVE P2-LIGAND, 3,-5-DIMETHYLBIPHENYL P1-LIGAND) | MULTIDRUG-RESISTANT STRAINS, HYDROLASE INHIBITOR COMPLEX, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4zm1:A (LYS5) to (ILE20) SHIGELLA FLEXNERI LIPOPOLYSACCHARIDE O-ANTIGEN CHAIN-LENGTH REGULATOR WZZBSF - WILD TYPE | LIPOPOLYSACCHARIDE, CHAIN-LENGTH, VIRULENCE, SEROSPECIFICITY, MEMBRANE PROTEIN
1h4t:D (THR228) to (PHE240) PROLYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH L-PROLINE | AMINOACYL-TRNA SYNTHETASE, ATP + L-PROLINE + TRNA(PRO) AMP + PPI + L-PROLYL-TRNA(PRO), CLASS II AMINOACYL-TRNA SYNTHETASE
2gna:A (ASN321) to (LEU333) CRYSTAL STRUCTURE OF UDP-GLCNAC INVERTING 4,6-DEHYDRATASE IN COMPLEX WITH NADP AND UDP-GAL | ROSSMANN FOLD, TYK TRIAD, SDR, ENZYME, DEHYDRATASE, UDP-GLCNAC, NADP, LYASE
4zne:J (GLN342) to (ASN361) IGG1 FC-FCGAMMARI ECD COMPLEX | ANTIBODY, CONSTANT REGION, RECEPTOR, HIGH AFFINITY, IMMUNE SYSTEM
4l6v:B (THR508) to (ALA538) CRYSTAL STRUCTURE OF A VIRUS LIKE PHOTOSYSTEM I FROM THE CYANOBACTERIUM SYNECHOCYSTIS PCC 6803 | PHOTOSYNTHETIC REACTION CENTER, MEMBRANE COMPLEX, PLASTOCYANIN, CYTOCHROME C6, FERREDOXIN, ELECTRON TRANSPORT
1t7k:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH ARYLSULFONAMIDE AZACYCLIC UREA | HIV PROTEASE, ARYLSULFONAMIDE AZACYCLIC UREA, HYDROLASE
1t83:A (GLN342) to (ASN361) CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (ORTHORHOMBIC) | FC GAMMA RECEPTOR, IGG1, CD16, FCGRIII, IMMUNOGLOBULIN, IMMUNE SYSTEM
2grx:A (SER49) to (HIS61) CRYSTAL STRUCTURE OF TONB IN COMPLEX WITH FHUA, E. COLI OUTER MEMBRANE RECEPTOR FOR FERRICHROME | BETA BARREL, OUTER MEMBRANE, HETEROCOMPLEX, INTER-PROTEIN BETA SHEET, PROTEIN-PROTEIN, METAL TRANSPORT
2grx:B (SER49) to (HIS61) CRYSTAL STRUCTURE OF TONB IN COMPLEX WITH FHUA, E. COLI OUTER MEMBRANE RECEPTOR FOR FERRICHROME | BETA BARREL, OUTER MEMBRANE, HETEROCOMPLEX, INTER-PROTEIN BETA SHEET, PROTEIN-PROTEIN, METAL TRANSPORT
4l9m:A (GLY515) to (TYR533) AUTOINHIBITED STATE OF THE RAS-SPECIFIC EXCHANGE FACTOR RASGRP1 | RAS NUCLEOTIDE EXCHANGE FACTOR, SIGNALING PROTEIN
2w4a:C (GLY135) to (SER148) ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE | CONTRACTILE PROTEIN, NUCLEOTIDE-BINDING, METHYLATION, ATP-BINDING, TROPOMYOSIN, ISOMETRIC CONTRACTION, MULTIVARIATE DATA ANALYSIS, FREEZING, MICROTOMY, FREEZE SUBSTITUTION, MUSCLE PROTEIN, IMAGE PROCESSING, CALMODULIN-BINDING, MOTOR PROTEIN, PHOSPHOPROTEIN, THICK FILAMENT, LIGHT CHAINS, ACTIN-BINDING, THIN FILAMENT, ACTIN, INSECT, MYOSIN, MUSCLE, TROPONIN
2w4b:B (TYR284) to (ASN316) EPSTEIN-BARR VIRUS ALKALINE NUCLEASE D203S MUTANT | EXONUCLEASE, ENDONUCLEASE, GAMMA-HERPESVIRUS, EBV, BGLF5, DNASE, NUCLEASE, HYDROLASE, HERPESVIRUS, EPSTEIN-BARR VIRUS
2w4g:C (GLY135) to (SER148) ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE QUICK FROZEN AFTER A QUICK STRETCH STEP | CONTRACTILE PROTEIN, METHYLATION, ATP-BINDING, ISOMETRIC CONTRACTION, MICROTOMY, FREEZE SUBSTITUTION, MUSCLE PROTEIN, CALMODULIN-BINDING, MOTOR PROTEIN, ACTIN-BINDING
2w4h:C (GLY135) to (SER148) ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE QUICK FROZEN AFTER A QUICK RELEASE STEP | CONTRACTILE PROTEIN, METHYLATION, ATP-BINDING, ISOMETRIC CONTRACTION, MICROTOMY, FREEZE SUBSTITUTION, MUSCLE PROTEIN, CALMODULIN-BINDING, MOTOR PROTEIN, ACTIN-BINDING
4zra:C (PRO37) to (LEU55) CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS LPRG BINDING TO TRIACYLGLYCERIDE | LPRG, LIPOPROTEIN, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, LIPID BINDING PROTEIN
1h98:A (ALA53) to (GLY76) NEW INSIGHTS INTO THERMOSTABILITY OF BACTERIAL FERREDOXINS: HIGH RESOLUTION CRYSTAL STRUCTURE OF THE SEVEN-IRON FERREDOXIN FROM THERMUS THERMOPHILUS | ELECTRON TRANSPORT, THERMOPHILIC, IRON-SULFUR, AZOTOBACTER, HYDROGEN BONDS, STABILITY, HIGH RESOLUTION
2gvg:A (THR468) to (ALA480) CRYSTAL STRUCTURE OF HUMAN NMPRTASE AND ITS COMPLEX WITH NMN | NMPRTASE, VISFATIN, PBEF, CRYSTAL, CANCER, TRANSFERASE
2gvg:B (THR468) to (ALA480) CRYSTAL STRUCTURE OF HUMAN NMPRTASE AND ITS COMPLEX WITH NMN | NMPRTASE, VISFATIN, PBEF, CRYSTAL, CANCER, TRANSFERASE
1hbv:A (ASN83) to (GLY94) A CHECK ON RATIONAL DRUG DESIGN. CRYSTAL STRUCTURE OF A COMPLEX OF HIV-1 PROTEASE WITH A NOVEL GAMMA-TURN MIMETIC | HYDROLASE (ACID PROTEASE)
1hbv:B (ASN83) to (GLY94) A CHECK ON RATIONAL DRUG DESIGN. CRYSTAL STRUCTURE OF A COMPLEX OF HIV-1 PROTEASE WITH A NOVEL GAMMA-TURN MIMETIC | HYDROLASE (ACID PROTEASE)
3inu:N (THR109) to (GLY128) CRYSTAL STRUCTURE OF AN UNBOUND KZ52 NEUTRALIZING ANTI-EBOLAVIRUS ANTIBODY. | ANTIBODY FRAGMENT (FAB), IMMUNOGLOBULIN FOLD, IMMUNE SYSTEM
1hef:E (ASN83) to (GLY94) THE CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF HYDROXYETHYLENE- BASED INHIBITORS BOUND TO HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE SHOW THAT THE INHIBITORS ARE PRESENT IN TWO DISTINCT ORIENTATIONS | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3iqs:A (GLU254) to (LYS270) CRYSTAL STRUCTURE OF THE ANTI-VIRAL APOBEC3G CATALYTIC DOMAIN | FIVE BETA-STRANDS SURROUNDED BY SIX ALPHA-HELICES, ALTERNATIVE SPLICING, ANTIVIRAL DEFENSE, CYTOPLASM, HOST- VIRUS INTERACTION, HYDROLASE, METAL-BINDING, NUCLEUS, POLYMORPHISM, UBL CONJUGATION, ZINC
4zv3:A (LYS161) to (MET206) CRYSTAL STRUCTURE OF THE N- AND C-TERMINAL DOMAINS OF MOUSE ACYL-COA THIOESTERASE 7 | THIOESTERASE, DOUBLE HOTDOG, INFLAMMATION, HYDROLASE
4zv3:B (LYS161) to (GLU207) CRYSTAL STRUCTURE OF THE N- AND C-TERMINAL DOMAINS OF MOUSE ACYL-COA THIOESTERASE 7 | THIOESTERASE, DOUBLE HOTDOG, INFLAMMATION, HYDROLASE
4zv3:C (LYS161) to (GLU207) CRYSTAL STRUCTURE OF THE N- AND C-TERMINAL DOMAINS OF MOUSE ACYL-COA THIOESTERASE 7 | THIOESTERASE, DOUBLE HOTDOG, INFLAMMATION, HYDROLASE
2h3b:A (THR468) to (ALA480) CRYSTAL STRUCTURE OF MOUSE NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE/VISFATIN/PRE-B CELL COLONY ENHANCING FACTOR 1 | APOENZYME, TYPE II PHSOPHORIBOSYLTRANSFERASE
2h3e:A (VAL122) to (THR148) STRUCTURE OF WILD-TYPE E. COLI ASPARTATE TRANSCARBAMOYLASE IN THE PRESENCE OF N-PHOSPHONACETYL-L-ISOASPARAGINE AT 2.3A RESOLUTION | COOPERATIVITY, TRANSFERASE
2h3e:C (PRO123) to (GLY150) STRUCTURE OF WILD-TYPE E. COLI ASPARTATE TRANSCARBAMOYLASE IN THE PRESENCE OF N-PHOSPHONACETYL-L-ISOASPARAGINE AT 2.3A RESOLUTION | COOPERATIVITY, TRANSFERASE
1tl9:A (ASN184) to (ASN199) HIGH RESOLUTION CRYSTAL STRUCTURE OF CALPAIN I PROTEASE CORE IN COMPLEX WITH LEUPEPTIN | COVALENTLY-LINKED INHIBITOR AT THE ACTIVE SITE CYSTEINE FORMS A HEMITHIOACETAL, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4lk0:C (GLY266) to (ASP281) CRYSTAL STRUCTURE ANALYSIS OF THE E.COLI HOLOENZYME/T7 GP2 COMPLEX | DNA DIRECTED RNA POLYMERASE, TRANSFERASE
4lk0:I (GLY266) to (ASP281) CRYSTAL STRUCTURE ANALYSIS OF THE E.COLI HOLOENZYME/T7 GP2 COMPLEX | DNA DIRECTED RNA POLYMERASE, TRANSFERASE
1hnb:B (TYR40) to (GLY53) CRYSTAL STRUCTURE OF HUMAN CLASS MU GLUTATHIONE TRANSFERASE GSTM2-2: EFFECTS OF LATTICE PACKING ON CONFORMATIONAL HETEROGENEITY | TRANSFERASE(GLUTATHIONE)
2hc0:A (ASN1083) to (GLY1094) STRUCTURE OF HIV PROTEASE 6X MUTANT IN COMPLEX WITH AB-2. | HIV, PROTEASE, MUTANT, ASPARTYL, HYDROLASE
2hch:A (GLU74) to (ASN96) N-DOMAIN OF GRP94 IN COMPLEX WITH THE NOVEL LIGAND N-(2- AMINO)ETHYL CARBOXYAMIDO ADENOSINE | GRP94, HSP82, HSP90, HTPG, CHAPERONE, LIGAND, NECA, NPCA, NEACA, NEOCA, ADENOSINE
2hcv:A (PHE50) to (THR61) CRYSTAL STRUCTURE OF L-RHAMNOSE ISOMERASE FROM PSEUDOMONAS STUTZERI WITH METAL ION | BETA/ALPHA BARREL, TIM BARREL, HOMO-TETRAMER, METAL-BINDING PROTEIN, ISOMERASE
1hps:B (ASN83) to (GLY94) RATIONAL DESIGN, SYNTHESIS AND CRYSTALLOGRAPHIC ANALYSIS OF A HYDROXYETHYLENE-BASED HIV-1 PROTEASE INHIBITOR CONTAINING A HETEROCYCLIC P1'-P2' AMIDE BOND ISOSTERE | HYDROLASE(ACID PROTEINASE)
1hpv:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH VX-478, A POTENT AND ORALLY BIOAVAILABLE INHIBITOR OF THE ENZYME | HYDROLASE (ACID PROTEINASE)
1hpx:B (ASN83) to (GLY94) HIV-1 PROTEASE COMPLEXED WITH THE INHIBITOR KNI-272 | ACID PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1tth:C (VAL122) to (THR148) ASPARTATE TRANSCARBAMOYLASE CATALYTIC CHAIN MUTANT GLU50ALA COMPLEXED WITH N-(PHOSPHONACETYL-L-ASPARTATE) (PALA) | SITE-SPECIFIC MUTAGENESIS, DOMAIN CLOSURE, ALLOSTERIC TRANSITION, HYDROLASE/HYDROLASE REGULATOR COMPLEX
1hte:A (ASN83) to (GLY94) X-RAY CRYSTALLOGRAPHIC STUDIES OF A SERIES OF PENICILLIN- DERIVED ASYMMETRIC INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEINASE)
1htg:B (ASN83) to (GLY94) X-RAY CRYSTALLOGRAPHIC STUDIES OF A SERIES OF PENICILLIN- DERIVED ASYMMETRIC INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEINASE)
2hje:A (LEU183) to (ASN207) CRYSTAL STRUCTURE OF VIBRIO HARVEYI LUXQ PERIPLASMIC DOMAIN | PER/ARNT/SIMPLE-MINDED (PAS) FOLD, AUTOINDUCER-2 (AI-2), QUORUM SENSING, HISTIDINE SENSOR KINASE, SIGNALING PROTEIN
2hk1:C (GLY59) to (ASN73) CRYSTAL STRUCTURE OF D-PSICOSE 3-EPIMERASE (DPEASE) IN THE PRESENCE OF D-FRUCTOSE | TIM-BARREL, ISOMERASE
3vsm:A (THR655) to (GLY670) THE CRYSTAL STRUCTURE OF NOVEL CHONDROITION LYASE ODV-E66, BACULOVIRUS ENVELOPE PROTEIN | ALPHA/ALPHA TROID, BETA-SANDWICH, LYASE ACTIVATOR
1hvi:A (ASN83) to (GLY94) INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEASE)
1hvj:A (ASN83) to (GLY94) INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEASE)
1hvk:A (ASN83) to (GLY94) INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEASE)
1hvr:A (ASN83) to (GLY94) RATIONAL DESIGN OF POTENT, BIOAVAILABLE, NONPEPTIDE CYCLIC UREAS AS HIV PROTEASE INHIBITORS | HYDROLASE, ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1hvs:A (ASN83) to (GLY94) STRUCTURAL BASIS OF DRUG RESISTANCE FOR THE V82A MUTANT OF HIV-1 PROTEASE: BACKBONE FLEXIBILITY AND SUBSITE REPACKING | HYDROLASE (ACID PROTEASE)
1hvs:B (ASN83) to (GLY94) STRUCTURAL BASIS OF DRUG RESISTANCE FOR THE V82A MUTANT OF HIV-1 PROTEASE: BACKBONE FLEXIBILITY AND SUBSITE REPACKING | HYDROLASE (ACID PROTEASE)
2wj0:B (LEU58) to (GLY78) CRYSTAL STRUCTURES OF HOLLIDAY JUNCTION RESOLVASES FROM ARCHAEOGLOBUS FULGIDUS BOUND TO DNA SUBSTRATE | HYDROLASE DNA COMPLEX, TYPE II RESTRICTION ENDONUCLEASE, HOLLIDAY JUNCTION RESOLVASE, HYDROLASE, DNA BINDING PROTEIN
4lnu:K (ASN8) to (GLY26) NUCLEOTIDE-FREE KINESIN MOTOR DOMAIN IN COMPLEX WITH TUBULIN AND A DARPIN | ALPHA-TUBULIN, APO-KINESIN, BETA-TUBULIN, DARPIN, KINESIN, MICROTUBULE, TUBULIN, CELL CYCLE-MOTOR PROTEIN COMPLEX
1hwr:B (ASN83) to (GLY94) MOLECULAR RECOGNITION OF CYCLIC UREA HIV PROTEASE INHIBITORS | ASPARTYL PROTEASE, HYDROLASE, ACID PROTEINASE
1tyz:A (VAL257) to (GLU267) CRYSTAL STRUCTURE OF 1-AMINOCYCLOPROPANE-1-CARBOYXLATE DEAMINASE FROM PSEUDOMONAS | ACCD, COMPLEX, CRYSTAL, PLP, INHIBITOR, HYDROLASE
1tyz:D (VAL257) to (GLU267) CRYSTAL STRUCTURE OF 1-AMINOCYCLOPROPANE-1-CARBOYXLATE DEAMINASE FROM PSEUDOMONAS | ACCD, COMPLEX, CRYSTAL, PLP, INHIBITOR, HYDROLASE
1hxw:A (ASN83) to (GLY94) HIV-1 PROTEASE DIMER COMPLEXED WITH A-84538 | ASPARTYL PROTEASE, HYDROLASE, ASPARTIC PROTEINASE, HIV, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3vu8:A (ASP90) to (GLY115) METIONYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH METHIONYL-ADENYLATE ANALOGUE | PROTEIN MET-AMP COMPLEX, LIGASE
1tzh:L (THR109) to (GLY128) CRYSTAL STRUCTURE OF THE FAB YADS1 COMPLEXED WITH H-VEGF | PHAGE DISPLAY, ANTIBODY LIBRARY, PROTEIN ENGINEERING, IMMUNE SYSTEM
1tzj:C (VAL257) to (GLU267) CRYSTAL STRUCTURE OF 1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE COMPLEXED WITH D-VINYL GLYCINE | ACCD, SUBSTRATE, PLP, CRYSTAL, COMPLEX, HYDROLASE
1tzj:D (VAL257) to (GLU267) CRYSTAL STRUCTURE OF 1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE COMPLEXED WITH D-VINYL GLYCINE | ACCD, SUBSTRATE, PLP, CRYSTAL, COMPLEX, HYDROLASE
1hzh:H (GLN363) to (ASN384) CRYSTAL STRUCTURE OF THE INTACT HUMAN IGG B12 WITH BROAD AND POTENT ACTIVITY AGAINST PRIMARY HIV-1 ISOLATES: A TEMPLATE FOR HIV VACCINE DESIGN | IMMUNOGLOBULIN, ANTIBODY, B12, IMMUNE SYSTEM
2wkz:A (ASN83) to (GLY94) HIV-1 PROTEASE INHIBITORS CONTAINING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMIC WITH IMPROVED CELL-BASED ANTIVIRAL ACTIVITY | TRANSITION-STATE MIMIC, INHIBITOR, HYDROLASE
2wkz:B (ASN183) to (GLY194) HIV-1 PROTEASE INHIBITORS CONTAINING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMIC WITH IMPROVED CELL-BASED ANTIVIRAL ACTIVITY | TRANSITION-STATE MIMIC, INHIBITOR, HYDROLASE
4lqi:F (HIS221) to (ILE240) YEAST 20S PROTEASOME IN COMPLEX WITH VIBRALACTONE | BETA-LACTONE, INHIBITOR, NATURAL PRODUCT, TARGET IDENTIFICATION, NTN- PROTEASE, CELLULAR PROTEIN DEGRADATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4lqi:T (HIS221) to (ILE240) YEAST 20S PROTEASOME IN COMPLEX WITH VIBRALACTONE | BETA-LACTONE, INHIBITOR, NATURAL PRODUCT, TARGET IDENTIFICATION, NTN- PROTEASE, CELLULAR PROTEIN DEGRADATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3vvt:B (MET1) to (GLY16) CRYSTAL STRUCTURE OF RECONSTRUCTED ARCHAEAL ANCESTRAL NDK, ARC1 | NDK, ARCHAEA, ANCESTOR, TRANSFERASE
3vvu:A (MET1) to (GLY16) CRYSTAL STRUCTURE OF RECONSTRUCTED BACTERIAL ANCESTRAL NDK, BAC1 | NDK, BACTERIA, ANCESTOR, TRANSFERASE
3vvu:B (MET1) to (GLY16) CRYSTAL STRUCTURE OF RECONSTRUCTED BACTERIAL ANCESTRAL NDK, BAC1 | NDK, BACTERIA, ANCESTOR, TRANSFERASE
3vx7:A (ILE151) to (GLN169) CRYSTAL STRUCTURE OF KLUYVEROMYCES MARXIANUS ATG7NTD-ATG10 COMPLEX | UBIQUITIN CONJUGATION, E1-E2 COMPLEX, LIGASE
2hro:A (PHE449) to (ALA463) STRUCTURE OF THE FULL-LENGHT ENZYME I OF THE PTS SYSTEM FROM STAPHYLOCOCCUS CARNOSUS | PTS, PROTEIN PHOSPHORYLATION, SUGAR TRANSPORT, HISTIDINE PHOSPHORYLATION, TRANSFERASE
1u0z:B (GLU74) to (ASN91) N-DOMAIN OF GRP94 LACKING THE CHARGED DOMAIN IN COMPLEX WITH RADICICOL | GRP94, HSP90, BERGERAT, CHAPERONE, ENDOPLASMIC RETICULUM, RADICICOL
1i39:A (GLU60) to (ARG72) RNASE HII FROM ARCHAEOGLOBUS FULGIDUS | MIXED BETA SHEET, HELIX-LOOP-HELIX, HYDROLASE
2wog:A (GLN20) to (SER36) INTERMEDIATE AND FINAL STATES OF HUMAN KINESIN EG5 IN COMPLEX WITH S-TRITYL-L-CYSTEINE | ATP-BINDING, MOTOR PROTEIN, MITOSIS, CELL CYCLE, MICROTUBULE, CELL DIVISION, PHOSPHOPROTEIN, NUCLEOTIDE-BINDING
2hse:A (PRO123) to (THR148) STRUCTURE OF D236A E. COLI ASPARTATE TRANSCARBAMOYLASE IN THE PRESENCE OF PHOSPHONOACETAMIDE AND L-ASPARTATE AT 2.60 A RESOLUTION | X-RAY CRYSTALLOGRAPHY, DOMAIN CLOSURE, ALLOSTERIC TRANSITION, TRANSFERASE
2hse:C (PRO123) to (THR148) STRUCTURE OF D236A E. COLI ASPARTATE TRANSCARBAMOYLASE IN THE PRESENCE OF PHOSPHONOACETAMIDE AND L-ASPARTATE AT 2.60 A RESOLUTION | X-RAY CRYSTALLOGRAPHY, DOMAIN CLOSURE, ALLOSTERIC TRANSITION, TRANSFERASE
4lts:B (THR468) to (ALA480) DISCOVERY OF POTENT AND EFFICACIOUS CYANOGUANIDINE-CONTAINING NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) INHIBITORS | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1i5o:C (VAL122) to (ILE145) CRYSTAL STRUCTURE OF MUTANT R105A OF E. COLI ASPARTATE TRANSCARBAMOYLASE | MUTANT ASPARTATE TRANSCARBAMOYLASE, T-STATE, PALA AT THE REGULATORY SITE, TRANSFERASE
4lvd:B (THR468) to (ALA480) FRAGMENT-BASED IDENTIFICATION OF AMIDES DERIVED FROM TRANS-2-(PYRIDIN- 3-YL)CYCLOPROPANECARBOXYLIC ACID AS POTENT INHIBITORS OF HUMAN NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4lyk:A (ASP280) to (ALA292) CRYSTAL STRUCTURE OF THE EAL DOMAIN OF C-DI-GMP SPECIFIC PHOSPHODIESTERASE YAHA IN COMPLEX WITH ACTIVATING COFACTOR MG++ | PGPG, PHOSPHODIESTERASE, TIM-BARREL, HYDROLASE
1ucg:A (ARG128) to (GLY144) CRYSTAL STRUCTURE OF RIBONUCLEASE MC1 N71T MUTANT | ALPHA PLUS BETA, HYDROLASE
2wte:A (VAL128) to (MSE140) THE STRUCTURE OF THE CRISPR-ASSOCIATED PROTEIN, CSA3, FROM SULFOLOBUS SOLFATARICUS AT 1.8 ANGSTROM RESOLUTION. | ANTIVIRAL PROTEIN, VIRAL RESISTANCE, WINGED HELIX-TURN-HELIX, RNAI, PRNAI NUCLEOTIDE-BINDING DOMAIN
4m19:A (GLY144) to (ARG157) DIHYDRODIPICOLINATE SYNTHASE FROM C. JEJUNI WITH PYRUVATE BOUND TO THE ACTIVE SITE AND LYSINE BOUND TO ALLOSTERIC SITE | SCHIFF-BASE, ALDOLASE, TIM BARREL, LYASE
4m1k:A (HIS675) to (LEU687) CRYSTAL STRUCTURE OF ELONGATION FACTOR G (EFG) | ELONGATION FACTOR G, TRANSLATION
4m27:A (THR9) to (ALA32) CRYSTAL STRUCTURE OF NON-HEME IRON OXYGENASE ORFP IN COMPLEX WITH FE AND L-ARG | HYDROXYLASE, FE BINDING, OXIDOREDUCTASE
1uh7:A (ASP120) to (SER145) CRYSTAL STRUCTURE OF RHIZOPUSPEPSIN AT PH 4.6 | PEPSIN, ASPARTIC PROTEINASE, HYDROLASE
4m2c:A (THR9) to (ALA32) CRYSTAL STRUCTURE OF NON-HEME IRON OXYGENASE ORFP IN COMPLEX WITH FE AND D-ARG | HYDROXYLASE, FE BINDING, OXIDOREDUCTASE
4m2g:C (THR9) to (ALA32) CRYSTAL STRUCTURE OF NON-HEME IRON OXYGENASE ORFP IN COMPLEX WITH FE, SUCCINATE, AND (3R,4R)-DIHYDROXY-L-ARG | HYDROXYLASE, FE BINDING, OXIDOREDUCTASE
2i4v:B (ASN283) to (GLY294) HIV-1 PROTEASE I84V, L90M WITH TMC126 | HIV-1 PROTEIN INHIBITOR MUTANT, HYDROLASE
2i4x:B (ASN283) to (GLY294) HIV-1 PROTEASE I84V, L90M WITH GS-8374 | HIV-1 PROTEASE I84VL90M INHIBITOR, HYDROLASE
2i4z:B (GLN345) to (LEU356) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN PPARGAMMA AND THE PARTIAL AGONIST LT127 (UREIDOFIBRATE DERIVATIVE). THIS STRUCTURE HAS BEEN OBTAINED FROM CRYSTALS SOAKED FOR 6 HOURS. | BUNDLE OF ALPHA-HELICES AND A SMALL FOUR-STRANDED BETA- SHEET, TRANSCRIPTION
2i6u:A (VAL1) to (ASP29) CRYSTAL STRUCTURE OF ORNITHINE CARBAMOYLTRANSFERASE COMPLEXED WITH CARBAMOYL PHOSPHATE AND L-NORVALINE FROM MYCOBACTERIUM TUBERCULOSIS (RV1656) AT 2.2 A | X-RAY CRYSTALLOGRAPHY, MYCOBACTERIUM TUBERCULOSIS, ORNITHINE CARBAMYOLTRANSFERASE, CARBAMOYL PHOSPHATE, L- NORVALINE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC
4m4d:A (GLY29) to (LEU54) CRYSTAL STRUCTURE OF LIPOPOLYSACCHARIDE BINDING PROTEIN | BETA BARREL, IMMUNE RESPONSE, LIPOPOLYSACCHARIDE, BLOOD, LIPID BINDING PROTEIN
4m4r:B (VAL28) to (GLY46) EPHA4 ECTODOMAIN COMPLEX WITH EPHRIN A5 | EPH RECEPTOR EPHRIN COMPLEX, TRANSFERASE
4m4r:H (ALA29) to (GLY46) EPHA4 ECTODOMAIN COMPLEX WITH EPHRIN A5 | EPH RECEPTOR EPHRIN COMPLEX, TRANSFERASE
3j1b:N (VAL502) to (LYS525) CRYO-EM STRUCTURE OF 8-FOLD SYMMETRIC RATCPN-ALPHA IN APO STATE | GROUP II CHAPERONIN, CHAPERONE
3j1e:Q (VAL502) to (ILE526) CRYO-EM STRUCTURE OF 9-FOLD SYMMETRIC RATCPN-BETA IN APO STATE | GROUP II CHAPERONIN, CHAPERONE
4m6q:B (THR468) to (ALA480) IDENTIFICATION OF AMIDES DERIVED FROM 1H-PYRAZOLO[3,4-B]PYRIDINE-5- CARBOXYLIC ACID AS POTENT INHIBITORS OF HUMAN NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2idw:B (ASN183) to (GLY194) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A POTENT NON-PEPTIDE INHIBITOR (UIC-94017) | HIV-1 PROTEASE, MUTANT, DIMER, INHIBITOR, UIC-94017, HYDROLASE
2ie0:A (GLY192) to (GLY205) CRYSTAL STRUCTURE OF ISONIAZID-RESISTANT I21V ENOYL-ACP(COA) REDUCTASE MUTANT ENZYME FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH NADH- INH | ENOYL-ACYL CARRIER PROTEIN, ISONIAZID, INHA, OXIDOREDUCTASE
1upj:A (ASN83) to (GLY94) HIV-1 PROTEASE COMPLEX WITH U095438 [3-[1-(4-BROMOPHENYL) ISOBUTYL]-4- HYDROXYCOUMARIN | HYDROLASE (ACID PROTEASE)
2ieh:B (ILE19) to (SER36) CRYSTAL STRUCTURE OF HUMAN KINESIN EG5 IN COMPLEX WITH (R)- MON97, A NEW MONASTROL-BASED INHIBITOR THAT BINDS AS (R)- ENANTIOMER | BETA-SHEET CORE, FLANKED BY THREE ALPHA-HELICES ON EACH SIDE, HYDROLASE
2ieo:B (ASN183) to (GLY194) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT I84V WITH A POTENT NON-PEPTIDE INHIBITOR (UIC-94017) | HIV-1 PROTEASE, MUTANT, I84V, DIMER, INHIBITOR, UIC-94017, TMC114, DARUNAVIR, HYDROLASE
2wzn:A (GLU326) to (GLU345) 3D STRUCTURE OF TET3 FROM PYROCOCCUS HORIKOSHII | PROTEASE, HYDROLASE, THERMOPHILIC, SELF-COMPARTMENTALISING
3we7:A (ARG250) to (ILE265) CRYSTAL STRUCTURE OF DIACETYLCHITOBIOSE DEACETYLASE FROM PYROCOCCUS HORIKOSHII | ROSSMANN FOLD, HYDROLASE, ZINC BINDING, DEACETYLATION
4me8:A (VAL95) to (ARG107) CRYSTAL STRUCTURE OF A SIGNAL PEPTIDASE I (EF3073) FROM ENTEROCOCCUS FAECALIS V583 AT 2.27 A RESOLUTION | PF00717 FAMILY, PEPTIDASE_S24, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, HYDROLASE
5aeq:B (GLY41) to (PHE55) NEURONAL CALCIUM SENSOR (NCS-1)FROM RATTUS NORVEGICUS | SIGNALING PROTEIN, CALCIUM SENSOR
1izh:B (ASN83) to (GLY94) INHIBITOR OF HIV PROTEASE WITH UNUSUAL BINDING MODE POTENTLY INHIBITING MULTI-RESISTANT PROTEASE MUTANTS | HIV-1 PROTEINASE, POTENT INHIBITOR, SUBSITE BINDING, HYDROLASE
1izi:A (ASN83) to (GLY94) INHIBITOR OF HIV PROTEASE WITH UNUSUAL BINDING MODE POTENTLY INHIBITING MULTI-RESISTANT PROTEASE MUTANTS | HIV-1 PROTEINASE, TRIPLE MUTANT, POTENT INHIBITOR, SUBSITE BINDING, HYDROLASE
5afp:A (GLY78) to (THR92) NEURONAL CALCIUM SENSOR-1 (NCS-1)FROM RATTUS NORVEGICUS COMPLEX WITH RHODOPSIN KINASE PEPTIDE FROM HOMO SAPIENS | SIGNALING PROTEIN
1j0b:E (LYS150) to (GLN177) CRYSTAL STRUCTURE ANALYSIS OF THE ACC DEAMINASE HOMOLOGUE COMPLEXED WITH INHIBITOR | PLP DEPENDENT, LYASE
2x2r:A (GLN20) to (SER36) CRYSTAL STRUCTURE OF HUMAN KINESIN EG5 IN COMPLEX WITH (R)-2-AMINO-3-((4-CHLOROPHENYL)DIPHENYLMETHYLTHIO)PROPANOIC ACID | MITOSIS, CELL CYCLE, MICROTUBULE, ATP-BINDING, MOTOR PROTEIN, CELL DIVISION
2ior:A (GLY3) to (LEU24) CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HTPG, THE ESCHERICHIA COLI HSP90, BOUND TO ADP | HEAT SHOCK PROTEIN, CHAPERONE, HSP90
5ah7:B (ASN183) to (GLY194) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON-PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
5ah9:B (ASN183) to (GLY194) DISUBSTITUTED BIS-THF MOIETIES AS NEW P2 LIGANDS IN NON- PEPTIDAL HIV-1 PROTEASE INHIBITORS (II) | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, BIS-THF BIS-DIOL
2x4z:A (PRO470) to (ARG489) CRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 4 IN COMPLEX WITH PF-03758309 | TRANSFERASE, NUCLEOTIDE-BINDING ATP-BINDING, PHOSPHOPROTEIN
2ipo:C (PRO123) to (THR148) E. COLI ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH N- PHOSPHONACETYL-L-ASPARAGINE | ASPARTATE TRANSCARBAMOYLASE, ALLOSTERIC, INHIBITOR DESIGN, DOMAIN CLOSURE, TRANSFERASE
3wkn:N (GLN342) to (ASN361) CRYSTAL STRUCTURE OF THE ARTIFICIAL PROTEIN AFFINGER P17 (AF.P17) COMPLEXED WITH FC FRAGMENT OF HUMAN IGG | IMMUNOGLOBULIN-LIKE BETA-SANDWICH, BINDING PROTEIN, IMMUNE SYSTEM
2isw:A (PRO44) to (SER57) STRUCTURE OF GIARDIA FRUCTOSE-1,6-BIPHOSPHATE ALDOLASE IN COMPLEX WITH PHOSPHOGLYCOLOHYDROXAMATE | CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE, GLYCOLYTIC PATHWAY, GIARDIA LAMBLIA, DRUG TARGET, X-RAY STRUCTURE, LYASE
2isw:B (PRO44) to (ASP58) STRUCTURE OF GIARDIA FRUCTOSE-1,6-BIPHOSPHATE ALDOLASE IN COMPLEX WITH PHOSPHOGLYCOLOHYDROXAMATE | CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE, GLYCOLYTIC PATHWAY, GIARDIA LAMBLIA, DRUG TARGET, X-RAY STRUCTURE, LYASE
3wkt:A (HIS597) to (ASP608) COMPLEX STRUCTURE OF AN OPEN FORM OF NADPH-CYTOCHROME P450 REDUCTASE AND HEME OXYGENASE-1 | HEME DEGRADATION, MICROSOMAL MEMBRANE, OXIDOREDUCTASE
2x7e:B (GLN20) to (SER36) CRYSTAL STRUCTURE OF HUMAN KINESIN EG5 IN COMPLEX WITH (R)-FLUORASTROL | MICROTUBULE, ATP-BINDING, MOTOR PROTEIN, CELL DIVISION, MITOSIS, INHIBITOR, CELL CYCLE, NUCLEOTIDE-BINDING, KSP
1v5c:A (ASP292) to (ALA315) THE CRYSTAL STRUCTURE OF THE INACTIVE FORM CHITOSANASE FROM BACILLUS SP. K17 AT PH3.7 | CHITOSAN DEGRADATION, HYDROLASE, GLYCOSIL HYDROLASE, FAMILY 8
1ja0:B (HIS601) to (ASP612) CYPOR-W677X | NADPH-CYTOCHROME P450 REDUCTASE, OXIDOREDUCTASE
1ja1:A (HIS601) to (ARG613) CYPOR-TRIPLE MUTANT | NADPH-CYTOCHROME P450 REDUCTASE, OXIDOREDUCTASE
1ja1:B (HIS601) to (ASP612) CYPOR-TRIPLE MUTANT | NADPH-CYTOCHROME P450 REDUCTASE, OXIDOREDUCTASE
1jb9:A (LYS247) to (TYR257) CRYSTAL STRUCTURE OF THE FERREDOXIN:NADP+ REDUCTASE FROM MAIZE ROOT AT 1.7 ANGSTROMS | ELECTRON TRANSPORT, OXIDOREDUCTASE
2x9w:A (PHE277) to (ASN290) STRUCTURE OF THE PILUS BACKBONE (RRGB) FROM STREPTOCOCCUS PNEUMONIAE | CELL ADHESION
2iwg:A (GLN342) to (ASN361) COMPLEX BETWEEN THE PRYSPRY DOMAIN OF TRIM21 AND IGG FC | ZINC, RNA-BINDING, ZINC-FINGER, DNA-BINDING, RIBONUCLEOPROTEIN, IMMUNOGLOBULIN DOMAIN, IMMUNOGLOBULIN C REGION, SYSTEMIC LUPUS ERYTHEMATOSUS, POLYMORPHISM, GLYCOPROTEIN, METAL-BINDING
2iwg:D (GLN342) to (ASN361) COMPLEX BETWEEN THE PRYSPRY DOMAIN OF TRIM21 AND IGG FC | ZINC, RNA-BINDING, ZINC-FINGER, DNA-BINDING, RIBONUCLEOPROTEIN, IMMUNOGLOBULIN DOMAIN, IMMUNOGLOBULIN C REGION, SYSTEMIC LUPUS ERYTHEMATOSUS, POLYMORPHISM, GLYCOPROTEIN, METAL-BINDING
3j3r:D (LEU739) to (GLU753) STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM | CLPC, MECA, AAA+ ATPASE, PROTEIN UNFOLDING, CHAPERONE
5an1:A (TYR41) to (LEU53) CRYSTALLOGRAPHIC STRUCTURE OF THE GLUTATHIONE S-TRANSFERASE FROM LITOPENAEUS VANNAMEI COMPLEXED WITH GLUTATHIONE | TRANSFERASE, GLUTATHIONE, XENOBIOTIC, DISULPHIDE BOND GST, MU- CLASS
5an1:B (TYR41) to (LEU53) CRYSTALLOGRAPHIC STRUCTURE OF THE GLUTATHIONE S-TRANSFERASE FROM LITOPENAEUS VANNAMEI COMPLEXED WITH GLUTATHIONE | TRANSFERASE, GLUTATHIONE, XENOBIOTIC, DISULPHIDE BOND GST, MU- CLASS
5an1:C (TYR41) to (LEU53) CRYSTALLOGRAPHIC STRUCTURE OF THE GLUTATHIONE S-TRANSFERASE FROM LITOPENAEUS VANNAMEI COMPLEXED WITH GLUTATHIONE | TRANSFERASE, GLUTATHIONE, XENOBIOTIC, DISULPHIDE BOND GST, MU- CLASS
5an1:H (TYR41) to (LEU53) CRYSTALLOGRAPHIC STRUCTURE OF THE GLUTATHIONE S-TRANSFERASE FROM LITOPENAEUS VANNAMEI COMPLEXED WITH GLUTATHIONE | TRANSFERASE, GLUTATHIONE, XENOBIOTIC, DISULPHIDE BOND GST, MU- CLASS
3j3t:F (ILE337) to (HIS362) STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM | CLPC, MECA, AAA+ ATPASE, PROTEIN UNFOLDING, CHAPERONE
2ixc:B (TRP29) to (GLY40) RMLC M. TUBERCULOSIS WITH DTDP-RHAMNOSE | ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS, EPIMERISE, EPIMERASE, EPIMERIZE
2ixc:C (TRP29) to (GLY40) RMLC M. TUBERCULOSIS WITH DTDP-RHAMNOSE | ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS, EPIMERISE, EPIMERASE, EPIMERIZE
2ixh:A (SER32) to (GLY43) RMLC P AERUGINOSA WITH DTDP-RHAMNOSE | ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS, EPIMERISE, EPIMERASE, EPIMERIZE
2ixh:B (SER32) to (CYS42) RMLC P AERUGINOSA WITH DTDP-RHAMNOSE | ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS, EPIMERISE, EPIMERASE, EPIMERIZE
2ixh:B (HIS144) to (GLY174) RMLC P AERUGINOSA WITH DTDP-RHAMNOSE | ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS, EPIMERISE, EPIMERASE, EPIMERIZE
2ixi:A (GLU142) to (GLY171) RMLC P AERUGINOSA WITH DTDP-XYLOSE | ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS, EPIMERISE, EPIMERASE, EPIMERIZE
2ixi:B (SER29) to (GLY40) RMLC P AERUGINOSA WITH DTDP-XYLOSE | ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS, EPIMERISE, EPIMERASE, EPIMERIZE
2ixi:B (GLU142) to (GLY171) RMLC P AERUGINOSA WITH DTDP-XYLOSE | ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS, EPIMERISE, EPIMERASE, EPIMERIZE
2ixk:A (SER32) to (CYS42) RMLC P AERUGINOSA WITH DTDP-4-KETO RHAMNNOSE (THE PRODUCT OF THE REACTION) | ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS, EPIMERISE, EPIMERASE, EPIMERIZE
2ixk:A (GLU145) to (GLY174) RMLC P AERUGINOSA WITH DTDP-4-KETO RHAMNNOSE (THE PRODUCT OF THE REACTION) | ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS, EPIMERISE, EPIMERASE, EPIMERIZE
2ixk:B (SER32) to (GLY43) RMLC P AERUGINOSA WITH DTDP-4-KETO RHAMNNOSE (THE PRODUCT OF THE REACTION) | ISOMERASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS, EPIMERISE, EPIMERASE, EPIMERIZE
2xcm:A (GLU4) to (ILE22) COMPLEX OF HSP90 N-TERMINAL, SGT1 CS AND RAR1 CHORD2 DOMAIN | CHAPERONE-PROTEIN BINDING COMPLEX, STRESS RESPONSE
1vdm:A (LYS3) to (LYS26) CRYSTAL STRUCTURE OF PURINE PHOSPHORIBOSYLTRANSFERASE FROM PYROCOCCUS HORIKOSHII OT3 | PURINE PHOSPHORIBOSYLTRANSFERASE, PYROCOCCUS HORIKOSHII, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
1vdm:B (LYS3) to (LYS21) CRYSTAL STRUCTURE OF PURINE PHOSPHORIBOSYLTRANSFERASE FROM PYROCOCCUS HORIKOSHII OT3 | PURINE PHOSPHORIBOSYLTRANSFERASE, PYROCOCCUS HORIKOSHII, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
1vdm:I (LYS3) to (LYS26) CRYSTAL STRUCTURE OF PURINE PHOSPHORIBOSYLTRANSFERASE FROM PYROCOCCUS HORIKOSHII OT3 | PURINE PHOSPHORIBOSYLTRANSFERASE, PYROCOCCUS HORIKOSHII, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
1vdm:K (LYS3) to (LYS26) CRYSTAL STRUCTURE OF PURINE PHOSPHORIBOSYLTRANSFERASE FROM PYROCOCCUS HORIKOSHII OT3 | PURINE PHOSPHORIBOSYLTRANSFERASE, PYROCOCCUS HORIKOSHII, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
5apr:E (ASP120) to (SER145) STRUCTURES OF COMPLEXES OF RHIZOPUSPEPSIN WITH PEPSTATIN AND OTHER STATINE-CONTAINING INHIBITORS | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2xem:C (GLY128) to (VAL147) INDUCED-FIT AND ALLOSTERIC EFFECTS UPON POLYENE BINDING REVEALED BY CRYSTAL STRUCTURES OF THE DYNEMICIN THIOESTERASE | BIOSYNTHETIC PROTEIN, POLYKETIDE BIOSYNTHESIS, ENEDIYNE ANTITUMOR AGENT, THIOESTERASE
3wrv:A (ASP67) to (HIS78) CRYSTAL STRUCTURE OF NN DOMAIN OF RESISTANCE PROTEIN | ALPHA/BETA DOMAIN, RESISTANCE, TRANSFERASE
5at1:A (VAL122) to (GLY150) STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION | TRANSFERASE (CARBAMOYL-P,ASPARTATE)
5at1:C (VAL122) to (GLY150) STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION | TRANSFERASE (CARBAMOYL-P,ASPARTATE)
1vij:A (ASN83) to (GLY94) HIV-1 PROTEASE COMPLEXED WITH THE INHIBITOR HOE/BAY 793 HEXAGONAL FORM | ASPARTYL PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS, HOE/BAY 793: INHIBITOR DESIGN
2j6e:A (GLN342) to (ASN361) CRYSTAL STRUCTURE OF AN AUTOIMMUNE COMPLEX BETWEEN A HUMAN IGM RHEUMATOID FACTOR AND IGG1 FC REVEALS A NOVEL FC EPITOPE AND EVIDENCE FOR AFFINITY MATURATION | AUTOIMMUNE COMPLEX HUMAN IGM RHEUMATOID FACTOR IGG1-FC, IMMUNOGLOBULIN C REGION, MEMBRANE, GLYCOPROTEIN, TRANSMEMBRANE, HYPOTHETICAL PROTEIN, IMMUNE SYSTEM, IMMUNOGLOBULIN DOMAIN
3j6d:A (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:B (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:C (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:D (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:E (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:F (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:G (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:H (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:I (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:J (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:K (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:L (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:M (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:N (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:O (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:P (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:Q (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:R (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:S (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:T (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:U (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:V (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:W (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
3j6d:X (ARG221) to (ASP237) MODEL OF THE PRGH-PRGK PERIPLASMIC RINGS | BACTERIAL SECRESSION MACROMOLECULAR ASSEMBLIES, STRUCTURAL PROTEIN
1vlr:A (GLU77) to (GLY99) CRYSTAL STRUCTURE OF MRNA DECAPPING ENZYME (DCPS) FROM MUS MUSCULUS AT 1.83 A RESOLUTION | 16740816, MRNA DECAPPING ENZYME (DCPS), STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI, JOINT CENTER FOR STRUCTURAL GENOMICS, RNA BINDING PROTEIN
2xkb:I (VAL263) to (LEU274) CRYSTAL STRUCTURE OF GDP-FORM PROTOFILAMENTS OF BACILLUS THURINGIENSIS SEROVAR ISRAELENSIS TUBZ | STRUCTURAL PROTEIN, MOTOR PROTEIN, CYTOSKELETON, CYTOMOTIVE, DNA SEGREGATION, MICROTUBULE, PBTOXIS, PBT156, REPX, TUBR
3j70:B (THR109) to (SER127) MODEL OF GP120, INCLUDING VARIABLE REGIONS, IN COMPLEX WITH CD4 AND 17B | GP120, V1V2, CD4, 17B, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
3j70:N (THR109) to (SER127) MODEL OF GP120, INCLUDING VARIABLE REGIONS, IN COMPLEX WITH CD4 AND 17B | GP120, V1V2, CD4, 17B, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
3j70:S (THR109) to (SER127) MODEL OF GP120, INCLUDING VARIABLE REGIONS, IN COMPLEX WITH CD4 AND 17B | GP120, V1V2, CD4, 17B, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
4mx6:A (GLN299) to (LYS316) CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM SHEWANELLA ONEIDENSIS (SO_3134), TARGET EFI-510275, WITH BOUND SUCCINATE | TRAP PERIPLASMIC SOLUTE BINDING FAMILY, ENZYME FUNCTION INITIATIVE, EFI, STRUCTURAL GENOMICS, TRANSPORT PROTEIN
1vst:A (PRO2) to (ASP20) SYMMETRIC SULFOLOBUS SOLFATARICUS URACIL PHOSPHORIBOSYLTRANSFERASE WITH BOUND PRPP AND GTP | URACIL, PHOSPHORIBOSYLTRANSFERASE, ALLOSTERIC REGULATION, SULFOLOBUS SOLFATARICUS, PRPP, GTP, GLYCOSYLTRANSFERASE, MAGNESIUM, TRANSFERASE
1vyt:B (ALA116) to (ALA135) BETA3 SUBUNIT COMPLEXED WITH AID | TRANSPORT PROTEIN, ION TRANSPORT/COMPLEX, CALCIUM CHANNEL BETA SUBUNIT, AID DOAMIN, ION TRANSPORT, IONIC CHANNEL, VOLTAGE-GATED CHANNEL, SH3 DOMAIN
4myk:A (GLY195) to (LYS206) CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI FORMIMINOGLUTAMASE (OXIDIZED) WITH MN2+2 AT PH 8.5 | ARGINASE/DEACETYLASE (A/B) FOLD, HYDROLASE
5ayx:A (GLY165) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE | QUINOLINATE PHOSPHORIBOSYLTRANSFERASE, NAD BIOSYNTHESIS, NADC, TRANSFERASE
5ayx:B (GLY166) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE | QUINOLINATE PHOSPHORIBOSYLTRANSFERASE, NAD BIOSYNTHESIS, NADC, TRANSFERASE
5ayx:D (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE | QUINOLINATE PHOSPHORIBOSYLTRANSFERASE, NAD BIOSYNTHESIS, NADC, TRANSFERASE
5ayy:A (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE REACTANT QUINOLINATE | TRANSFERASE
5ayy:C (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE REACTANT QUINOLINATE | TRANSFERASE
5ayy:D (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE REACTANT QUINOLINATE | TRANSFERASE
5ayy:E (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE REACTANT QUINOLINATE | TRANSFERASE
5ayy:H (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE REACTANT QUINOLINATE | TRANSFERASE
5ayy:I (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE REACTANT QUINOLINATE | TRANSFERASE
3j8b:F (ARG90) to (ASN110) MODEL OF THE HUMAN EIF3 PCI-MPN OCTAMER DOCKED INTO THE 43S-HCV IRES EM MAP | TRANSLATION
5ayz:A (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE | TRANSFERASE
5ayz:C (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE | TRANSFERASE
5ayz:D (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE | TRANSFERASE
5ayz:E (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE | TRANSFERASE
5ayz:F (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE | TRANSFERASE
5ayz:G (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE | TRANSFERASE
5ayz:H (LEU167) to (ALA178) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE | TRANSFERASE
5ayz:I (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE | TRANSFERASE
5ayz:J (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE | TRANSFERASE
5ayz:K (LEU167) to (ALA178) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE | TRANSFERASE
5ayz:L (LEU167) to (GLY179) CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE | TRANSFERASE
3j8c:F (ARG90) to (ASN110) MODEL OF THE HUMAN EIF3 PCI-MPN OCTAMER DOCKED INTO THE 43S EM MAP | TRANSLATION
3x17:B (TYR198) to (PRO220) CRYSTAL STRUCTURE OF METAGENOME-DERIVED GLYCOSIDE HYDROLASE FAMILY 9 ENDOGLUCANASE | (ALPHA/ALPHA)6 BARREL FOLD, CELLULASE, CARBOHYDRATE/SUGAR BINDING, HYDROLASE
2jbm:A (LEU169) to (GLY181) QPRTASE STRUCTURE FROM HUMAN | NAD, ENZYME, METABOLISM, TRANSFERASE, POLYMORPHISM, GLYCOSYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS
2jbm:B (LEU169) to (GLY181) QPRTASE STRUCTURE FROM HUMAN | NAD, ENZYME, METABOLISM, TRANSFERASE, POLYMORPHISM, GLYCOSYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS
2jbm:C (LEU169) to (GLY181) QPRTASE STRUCTURE FROM HUMAN | NAD, ENZYME, METABOLISM, TRANSFERASE, POLYMORPHISM, GLYCOSYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS
2jbm:D (LEU169) to (GLY181) QPRTASE STRUCTURE FROM HUMAN | NAD, ENZYME, METABOLISM, TRANSFERASE, POLYMORPHISM, GLYCOSYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS
2jbm:E (LEU169) to (GLY181) QPRTASE STRUCTURE FROM HUMAN | NAD, ENZYME, METABOLISM, TRANSFERASE, POLYMORPHISM, GLYCOSYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS
2jbm:F (LEU169) to (GLY181) QPRTASE STRUCTURE FROM HUMAN | NAD, ENZYME, METABOLISM, TRANSFERASE, POLYMORPHISM, GLYCOSYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS
2jbm:G (LEU169) to (GLY181) QPRTASE STRUCTURE FROM HUMAN | NAD, ENZYME, METABOLISM, TRANSFERASE, POLYMORPHISM, GLYCOSYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS
2jbm:H (LEU169) to (GLY181) QPRTASE STRUCTURE FROM HUMAN | NAD, ENZYME, METABOLISM, TRANSFERASE, POLYMORPHISM, GLYCOSYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS
2jbm:I (LEU169) to (GLY181) QPRTASE STRUCTURE FROM HUMAN | NAD, ENZYME, METABOLISM, TRANSFERASE, POLYMORPHISM, GLYCOSYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS
2jbm:J (LEU169) to (GLY181) QPRTASE STRUCTURE FROM HUMAN | NAD, ENZYME, METABOLISM, TRANSFERASE, POLYMORPHISM, GLYCOSYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS
2jbm:K (LEU169) to (GLY181) QPRTASE STRUCTURE FROM HUMAN | NAD, ENZYME, METABOLISM, TRANSFERASE, POLYMORPHISM, GLYCOSYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS
2jbm:L (LEU169) to (GLY181) QPRTASE STRUCTURE FROM HUMAN | NAD, ENZYME, METABOLISM, TRANSFERASE, POLYMORPHISM, GLYCOSYLTRANSFERASE, PYRIDINE NUCLEOTIDE BIOSYNTHESIS
3x43:E (PHE138) to (GLU154) CRYSTAL STRUCTURE OF O-UREIDO-L-SERINE SYNTHASE | D-CYCLOSERINE, TYPE II PLP ENZYME, SYNTHASE, TRANSFERASE
4n3e:Q (CYS126) to (ASN154) CRYSTAL STRUCTURE OF HYP-1, A ST JOHN'S WORT PR-10 PROTEIN, IN COMPLEX WITH 8-ANILINO-1-NAPHTHALENE SULFONATE (ANS) | PLANT HORMONE BINDING, PHYTOHORMONE BINDING, CYTOKININ, PLANT DEFENSE, PATHOGENESIS-RELATED PROTEIN, PR-10 PROTEIN, HYPERICIN, DEPRESSION, PR-10 FOLD, HYDROPHOBIC CAVITY, GLYCINE-RICH LOOP, ANS DISPLACEMENT ASSAY (ADA), COMMENSURATELY MODULATED SUPERSTRUCTURE, TETARTOHEDRAL TWINNING, PLANT PROTEIN
3zdd:A (LYS146) to (GLU157) STRUCTURE OF E. COLI EXOIX IN COMPLEX WITH THE PALINDROMIC 5OV6 OLIGONUCLEOTIDE AND POTASSIUM | HYDROLASE-DNA COMPLEX, ENDONUCLEASE, DNA BINDING
1w5w:B (ASN83) to (GLY94) HIV-1 PROTEASE IN COMPLEX WITH FLUORO SUBSTITUTED DIOL- BASED C2-SYMMETRIC INHIBITOR | HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE, DIMER, PROTEIN-INHIBITOR COMPLEX
1w5x:B (ASN83) to (GLY94) HIV-1 PROTEASE IN COMPLEX WITH FLUORO SUBSTITUTED DIOL- BASED C2-SYMMETRIC INHIBITOR | HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE, DIMER, PROTEIN-INHIBITOR COMPLEX
1w5y:B (ASN83) to (GLY94) HIV-1 PROTEASE IN COMPLEX WITH FLUORO SUBSTITUTED DIOL- BASED C2-SYMMETRIC INHIBITOR | HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE, DIMER, PROTEIN-INHIBITOR COMPLEX
2jfy:A (PRO88) to (GLN103) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI GLUTAMATE RACEMASE IN COMPLEX WITH D-GLUTAMATE | CELL WALL, ISOMERASE, CELL SHAPE, GLUTAMATE RACEMASE, PEPTIDOGLYCAN SYNTHESIS, PEPTIDOGLYCAN BIOSYNTHESIS
4n72:A (PRO423) to (ARG450) CATALYTIC DOMAIN FROM DIHYDROLIPOAMIDE ACETYLTRANSFERASE OF PYRUVATE DEHYDROGENASE FROM ESCHERICHIA COLI | DIHYDROLIPOAMIDE ACETYLTRANSFERASE CATALYTIC DOMAIN, PYRUVATE DEHYDROGENASE, ACETYLTRANSFERASE, TRANSFERASE
4n72:B (PRO423) to (LYS451) CATALYTIC DOMAIN FROM DIHYDROLIPOAMIDE ACETYLTRANSFERASE OF PYRUVATE DEHYDROGENASE FROM ESCHERICHIA COLI | DIHYDROLIPOAMIDE ACETYLTRANSFERASE CATALYTIC DOMAIN, PYRUVATE DEHYDROGENASE, ACETYLTRANSFERASE, TRANSFERASE
2jgz:A (HIS84) to (SER94) CRYSTAL STRUCTURE OF PHOSPHO-CDK2 IN COMPLEX WITH CYCLIN B | PROTEIN KINASE, UBL CONJUGATION, PHOSPHORYLATION, SERINE/THREONINE-PROTEIN KINASE, KINASE, CYCLIN, MITOSIS, CELL CYCLE, TRANSFERASE, ATP-BINDING, POLYMORPHISM, CELL DIVISION, NUCLEOTIDE-BINDING, SUBSTRATE SPECIFICITY
4n90:G (THR110) to (GLY129) CRYSTAL STRUCTURE OF TERNARY COMPLEX OF TRAIL, DR5, AND FAB FRAGMENT FROM A DR5 AGONIST ANTIBODY | DR5, TRAIL, AGONIST, ANTIBODY, COOPERATION, CLUSTERING, APOPTOSIS- IMMUNE SYSTEM COMPLEX
5bpg:D (GLN125) to (ARG140) CRYSTAL STRUCTURE OF THE WATER-SOLUBLE FRAC PURIFIED STARTING FROM THE TRANS-MEMBRANE PORE | ACTINOPORIN, PORE-FORMING TOXIN, MEMBRANE LIPIDS, LIPID-PROTEIN INTERACTION, PROTEIN FOLDING, DETERGENT, PROTEIN-DETERGENT INTERACTION, TOXIN
4n9j:A (ILE670) to (SER700) CRYSTAL STRUCTURE OF THE CRYPTIC POLO BOX DOMAIN OF HUMAN PLK4 | SER/THR KINASE, CELL CYCLE
3zgh:A (GLY321) to (GLY332) CRYSTAL STRUCTURE OF THE KRT10-BINDING REGION DOMAIN OF THE PNEUMOCOCCAL SERINE RICH REPEAT PROTEIN PSRP | STRUCTURAL PROTEIN, MSCRAMM, KERATIN-10
3zgi:A (GLY321) to (GLY332) CRYSTAL STRUCTURE OF THE KRT10-BINDING REGION DOMAIN OF THE PNEUMOCOCCAL SERINE RICH REPEAT PROTEIN PSRP | STRUCTURAL PROTEIN, ADHESIN, KERATIN-10, SRRP
3zgi:B (GLY321) to (GLY332) CRYSTAL STRUCTURE OF THE KRT10-BINDING REGION DOMAIN OF THE PNEUMOCOCCAL SERINE RICH REPEAT PROTEIN PSRP | STRUCTURAL PROTEIN, ADHESIN, KERATIN-10, SRRP
3zgi:C (GLY321) to (GLY332) CRYSTAL STRUCTURE OF THE KRT10-BINDING REGION DOMAIN OF THE PNEUMOCOCCAL SERINE RICH REPEAT PROTEIN PSRP | STRUCTURAL PROTEIN, ADHESIN, KERATIN-10, SRRP
3zh3:A (ASN80) to (ARG92) CRYSTAL STRUCTURE OF S. PNEUMONIAE D39 NATIVE MURA1 | TRANSFERASE, ENOLPYRUVYL TRANSFERASE, MURA
1k1t:B (ASN183) to (GLY194) COMBINING MUTATIONS IN HIV-1 PROTEASE TO UNDERSTAND MECHANISMS OF RESISTANCE | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1k1u:A (ASN83) to (GLY94) COMBINING MUTATIONS IN HIV-1 PROTEASE TO UNDERSTAND MECHANISMS OF RESISTANCE | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1k1u:B (ASN183) to (GLY194) COMBINING MUTATIONS IN HIV-1 PROTEASE TO UNDERSTAND MECHANISMS OF RESISTANCE | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1k2b:B (ASN83) to (GLY94) COMBINING MUTATIONS IN HIV-1 PROTEASE TO UNDERSTAND MECHANISMS OF RESISTANCE | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1k2c:A (ASN83) to (GLY94) COMBINING MUTATIONS IN HIV-1 PROTEASE TO UNDERSTAND MECHANISMS OF RESISTANCE | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1k2c:B (ASN83) to (GLY94) COMBINING MUTATIONS IN HIV-1 PROTEASE TO UNDERSTAND MECHANISMS OF RESISTANCE | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5bs4:B (ASN83) to (GLY94) HIV-1 WILD TYPE PROTEASE WITH GRL-047-11A (A METHYLAMINE BIS- TETRAHYDROFURAN P2-LIGAND, 4-AMINO SULFONAMIDE DERIVATIVE) | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2jje:A (CYS305) to (ALA317) CRYSTAL STRUCTURE OF T330S MUTANT OF RV3290C FROM M. TUBERCULOSIS | AMINOTRANSFERASE, PYRIDOXAL PHOSPHATE, PLP, RV3290C, TRANSFERASE, T330S MUTANT, LYSINE AMINO TRANSFERASE, MYCOBACTERIUM TUBERCULOSIS
2jjf:A (CYS305) to (ALA317) N328A MUTANT OF M. TUBERCULOSIS RV3290C | PLP, RV3290C, TRANSFERASE, N328A MUTANT, AMINOTRANSFERASE, PYRIDOXAL PHOSPHATE, LYSINE AMINO TRANSFERASE, MYCOBACTERIUM TUBERCULOSIS
1k32:A (VAL1031) to (GLY1043) CRYSTAL STRUCTURE OF THE TRICORN PROTEASE | PROTEIN DEGRADATION, SUBSTRATE GATING, SERINE PROTEASE, BETA PROPELLER, PROTEASOME, HYDROLASE
1k32:C (VAL1031) to (GLY1043) CRYSTAL STRUCTURE OF THE TRICORN PROTEASE | PROTEIN DEGRADATION, SUBSTRATE GATING, SERINE PROTEASE, BETA PROPELLER, PROTEASOME, HYDROLASE
1k32:F (VAL1031) to (GLY1043) CRYSTAL STRUCTURE OF THE TRICORN PROTEASE | PROTEIN DEGRADATION, SUBSTRATE GATING, SERINE PROTEASE, BETA PROPELLER, PROTEASOME, HYDROLASE
1wbk:B (ASN83) to (GLY94) HIV-1 PROTEASE IN COMPLEX WITH ASYMMETRIC INHIBITOR, BEA568 | HYDROLASE/INHIBITOR, HYDROLASE/INHIBITOR COMPLEX, AIDS, ASPARTYL PROTEASE, DIMER, HYDROLASE, HYDROLASE/HYDROLASE INHIBITOR, PROTEIN-INHIBITOR COMPLEX
1wbm:B (ASN83) to (GLY94) HIV-1 PROTEASE IN COMPLEX WITH SYMMETRIC INHIBITOR, BEA450 | HYDROLASE/INHIBITOR, HYDROLASE/INHIBITOR COMPLEX, AIDS, ASPARTYL PROTEASE, DIMER, HYDROLASE, HYDROLASE/HYDROLASE INHIBITOR, PROTEIN-INHIBITOR COMPLEX
2xye:B (ASN183) to (GLY194) HIV-1 INHIBITORS WITH A TERTIARY-ALCOHOL-CONTAINING TRANSITION-STATE MIMIC AND VARIOUS P2 AND P1 PRIME SUBSTITUENTS | HYDROLASE, AIDS
4nd8:B (ALA148) to (GLY159) AV NITROGENASE MOFE PROTEIN HIGH PH FORM | HIGH PH, OXIDOREDUCTASE, NITROGEN FIXATION, NIFH
4nd8:D (ALA148) to (GLY159) AV NITROGENASE MOFE PROTEIN HIGH PH FORM | HIGH PH, OXIDOREDUCTASE, NITROGEN FIXATION, NIFH
4ndo:B (ASP37) to (GLY52) CRYSTAL STRUCTURE MOLYBDENUM STORAGE PROTEIN WITH FULLY MO-LOADED CAVITY | ROSSMANN FOLD, MOLYBDENUM STORAGE, ATP BINDING, MOLYBDENUM BINDING, METAL BINDING PROTEIN
5buv:B (ASP144) to (LEU170) X-RAY STRUCTURE OF WBCA FROM YERSINIA ENTEROCOLITICA | LIPOPOLYSACCHARIDE, ISOMERASE
5bvg:B (ALA148) to (GLY159) SELENIUM INCORPORATED NITROGENASE MOFE-PROTEIN (AV1-SE2B) FROM A. VINELANDII | NITROGENASE, FEMO-COFACTOR, SE-INCORPORATION, OXIDOREDUCTASE
5bvh:B (ALA148) to (GLY159) CO-BOUND FORM OF SELENIUM INCORPORATED NITROGENASE MOFE-PROTEIN (AV1- SE-CO) FROM A. VINELANDII | NITROGENASE, FEMO-COFACTOR, SE-INCORPORATION, OXIDOREDUCTASE
5bvh:D (ALA148) to (GLY159) CO-BOUND FORM OF SELENIUM INCORPORATED NITROGENASE MOFE-PROTEIN (AV1- SE-CO) FROM A. VINELANDII | NITROGENASE, FEMO-COFACTOR, SE-INCORPORATION, OXIDOREDUCTASE
5bw7:B (GLN342) to (ASN361) CRYSTAL STRUCTURE OF NONFUCOSYLATED FC Y296W MUTANT COMPLEXED WITH BIS-GLYCOSYLATED SOLUBLE FORM OF FC GAMMA RECEPTOR IIIA | IMMUNE SYSTEM, COMPLEX, FC FRAGMENT, IGG, RECEPTOR, CD16, GAMMA
3zjt:A (GLU124) to (GLY147) TERNARY COMPLEX OF E .COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) 574 THE BENZOXABOROLE AN3017 IN THE EDITING CONFORMATION | LIGASE-RNA COMPLEX, NUCLEOTIDE (ATP) -BINDING, PROTEIN BIOSYNTHESIS, CLASS I AMINOACYL-TRNA SYNTHETASE, AMINOACYL TRNA SYNTHETASE, ATP BINDING, EDITING SYNTHETASE
1wkl:A (MET1) to (GLY16) CRYSTAL STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE FROM THERMUS THERMOPHILUS HB8 IN COMPLEX WITH ATP AND ADP | NUCLEOTIDE DIPHOSPHATE KINASE, COMPLEX WITH ATP AND ADP, REACTION INTERMEDIATE, THERMUS THERMOPHILUS HB8, KINASE, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, TRANSFERASE
1wlt:B (VAL30) to (ARG40) CRYSTAL STRUCTURE OF DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE HOMOLOGUE FROM SULFOLOBUS TOKODAII | JELLY ROLL-LIKE TOPOLOGY, FLATTENED BARREL, ISOMERASE
1kdv:A (GLY354) to (SER367) PSEUDOMONAS SERINE-CARBOXYL PROTEINASE COMPLEXED WITH THE INHIBITOR AIAF (THIS ENZYME RENAMED "SEDOLISIN" IN 2003) | SERINE-CARBOXYL PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1kdy:A (GLY354) to (SER367) PSEUDOMONAS SERINE-CARBOXYL PROTEINASE COMPLEXED WITH THE INHIBITOR AIPF (THIS ENZYME RENAMED "SEDOLISIN" IN 2003) | PSEUDOMONAS SERINE-CARBOXYL PROTEINASE AIPF, HYDROLASE-HYDROLASE INHIBITOR COMLPEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1kdz:A (GLY354) to (SER367) PSEUDOMONAS SERINE-CARBOXYL PROTEINASE COMPLEXED WITH THE INHIBITOR TYROSTATIN (THIS ENZYME RENAMED "SEDOLISIN" IN 2003) | SERINE-CARBOXYL PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ke1:A (GLY354) to (SER367) PSEUDOMONAS SERINE-CARBOXYL PROTEINASE COMPLEXED WITH THE INHIBITOR PSEUDOTYROSTATIN (THIS ENZYME RENAMED "SEDOLISIN" IN 2003) | SERINE-CARBOXYL PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2y4o:B (PHE67) to (TYR79) CRYSTAL STRUCTURE OF PAAK2 IN COMPLEX WITH PHENYLACETYL ADENYLATE | LIGASE, PHENYLACETIC ACID DEGRADATION PATHWAY
2y5w:A (ILE13) to (GLY30) CRYSTAL STRUCTURE OF DROSOPHILA MELANOGASTER KINESIN-1 MOTOR DOMAIN DIMER | MOTOR PROTEIN, MICROTUBULE ASSOCIATED, ATPASE
2y65:B (VAL339) to (LYS363) CRYSTAL STRUCTURE OF DROSOPHILA MELANOGASTER KINESIN-1 MOTOR DOMAIN DIMER-TAIL COMPLEX | MOTOR PROTEIN
3zps:B (ASN183) to (GLY194) DESIGN AND SYNTHESIS OF P1-P3 MACROCYCLIC TERTIARY ALCOHOL COMPRISING HIV-1 PROTEASE INHIBITORS | HYDROLASE, PROTEASE INHIBITOR, RATIONAL DRUG DESIGN,
1wu7:A (PHE310) to (ASN325) CRYSTAL STRUCTURE OF HISTIDYL-TRNA SYNTHETASE FROM THERMOPLASMA ACIDOPHILUM | LIGASE, STRUCTURAL GENOMICS, DIMER
2lc7:A (SER198) to (GLY210) SOLUTION STRUCTURE OF THE ISOLATED PAR-6 PDZ DOMAIN | CRIB, ALLOSTERY, CELL POLARITY, CELL ADHESION
4nnw:F (HIS224) to (ASN244) YCP IN COMPLEX WITH Z-LEU-LEU-LEU-KETOALDEHYDE | PROTEASOME, PEPTIDE ELECTROPHILE, BINDING ANALYSIS, REVERSIBLE INHIBITOR, KETOALDEHYDE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4nnw:T (HIS224) to (ASN244) YCP IN COMPLEX WITH Z-LEU-LEU-LEU-KETOALDEHYDE | PROTEASOME, PEPTIDE ELECTROPHILE, BINDING ANALYSIS, REVERSIBLE INHIBITOR, KETOALDEHYDE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1kj7:B (ASN83) to (GLY94) SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES | P2-NUCLEOCAPSID, SUBSTRATE RECOGNITION, HYDROLASE
1kjg:A (ASN83) to (GLY94) SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES | REVERSE TRANSCRIPTASE, RNASE H, SUBSTRATE RECOGNITION, HYDROLASE
1kjh:A (ASN83) to (GLY94) SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES | RNASE H, INTEGRASE, SUBSTRATE RECOGNITION, HYDROLASE
1kjh:B (ASN83) to (GLY94) SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES | RNASE H, INTEGRASE, SUBSTRATE RECOGNITION, HYDROLASE
4no1:T (HIS224) to (ASN244) YCP IN COMPLEX WITH Z-LEU-LEU-LEU-B(OH)2 | PROTEASOME, PEPTIDE ELECTROPHILE, BINDING ANALYSIS, IRREVERSIBLE INHIBITOR, BORONIC ACID, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4nos:B (VAL431) to (SER453) HUMAN INDUCIBLE NITRIC OXIDE SYNTHASE WITH INHIBITOR | L-ARGININE MONOOXYGENASE, NITRIC OXIDE, HUMAN, ZNS4, OXIDOREDUCTASE
4nos:C (VAL431) to (GLY455) HUMAN INDUCIBLE NITRIC OXIDE SYNTHASE WITH INHIBITOR | L-ARGININE MONOOXYGENASE, NITRIC OXIDE, HUMAN, ZNS4, OXIDOREDUCTASE
1kmn:C (PHE305) to (PRO321) HISTIDYL-TRNA SYNTHETASE COMPLEXED WITH HISTIDINOL AND ATP | AMINOACYL-TRNA SYNTHASE, LIGASE, SYNTHETASE
1kmn:D (PHE305) to (PRO321) HISTIDYL-TRNA SYNTHETASE COMPLEXED WITH HISTIDINOL AND ATP | AMINOACYL-TRNA SYNTHASE, LIGASE, SYNTHETASE
1knx:B (VAL53) to (LYS67) HPR KINASE/PHOSPHATASE FROM MYCOPLASMA PNEUMONIAE | HPR KINASE, HPR KINASE/PHOSPHATASE, HPRK/P, KINASE, PHOSPHATASE, P-LOOP, WALKER A BOX, CATABOLITE REPRESSION, TRANSFERASE/HYDROLASE COMPLEX
1x1o:B (GLY168) to (GLY180) CRYSTAL STRUCTURE OF PROJECT ID TT0268 FROM THERMUS THERMOPHILUS HB8 | TRANSFERASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
1x1o:C (GLY168) to (ALA179) CRYSTAL STRUCTURE OF PROJECT ID TT0268 FROM THERMUS THERMOPHILUS HB8 | TRANSFERASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2me7:A (SER2) to (SER13) NMR SOLUTION STRUCTURE OF THE GS-TAMAPIN MUTATION R6A | SCORPION TOXIN, TAMAPIN, ALPHA KTX5.4 MUTANT R6A, TOXIN
1kpp:A (GLY107) to (TRP117) STRUCTURE OF THE TSG101 UEV DOMAIN | E2 FOLD, CELL CYCLE
5c4v:C (VAL437) to (THR453) SKI-LIKE PROTEIN | COMPLEX, SIGNALING PROTEIN
3zwg:A (GLN125) to (SER141) CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN FRAC FROM ACTINIA FRAGACEA (FORM 2) | TOXIN, ION TRANSPORT, MEMBRANE PROTEIN, ACTINOPORINS
3zwg:B (GLN125) to (SER141) CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN FRAC FROM ACTINIA FRAGACEA (FORM 2) | TOXIN, ION TRANSPORT, MEMBRANE PROTEIN, ACTINOPORINS
3zwg:E (GLN125) to (SER141) CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN FRAC FROM ACTINIA FRAGACEA (FORM 2) | TOXIN, ION TRANSPORT, MEMBRANE PROTEIN, ACTINOPORINS
3zwg:F (GLN125) to (SER141) CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN FRAC FROM ACTINIA FRAGACEA (FORM 2) | TOXIN, ION TRANSPORT, MEMBRANE PROTEIN, ACTINOPORINS
3zwg:I (GLN125) to (SER141) CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN FRAC FROM ACTINIA FRAGACEA (FORM 2) | TOXIN, ION TRANSPORT, MEMBRANE PROTEIN, ACTINOPORINS
3zwg:J (GLN125) to (SER141) CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN FRAC FROM ACTINIA FRAGACEA (FORM 2) | TOXIN, ION TRANSPORT, MEMBRANE PROTEIN, ACTINOPORINS
3zwg:K (GLN125) to (SER141) CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN FRAC FROM ACTINIA FRAGACEA (FORM 2) | TOXIN, ION TRANSPORT, MEMBRANE PROTEIN, ACTINOPORINS
3zwg:L (GLN125) to (SER141) CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN FRAC FROM ACTINIA FRAGACEA (FORM 2) | TOXIN, ION TRANSPORT, MEMBRANE PROTEIN, ACTINOPORINS
3zwg:M (GLN125) to (SER141) CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN FRAC FROM ACTINIA FRAGACEA (FORM 2) | TOXIN, ION TRANSPORT, MEMBRANE PROTEIN, ACTINOPORINS
3zwg:N (GLN125) to (SER141) CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN FRAC FROM ACTINIA FRAGACEA (FORM 2) | TOXIN, ION TRANSPORT, MEMBRANE PROTEIN, ACTINOPORINS
3zwg:O (GLN125) to (SER141) CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN FRAC FROM ACTINIA FRAGACEA (FORM 2) | TOXIN, ION TRANSPORT, MEMBRANE PROTEIN, ACTINOPORINS
1x9j:B (GLU349) to (SER368) STRUCTURE OF BUTYRATE KINASE 2 REVEALS BOTH OPEN- AND CITRATE-INDUCED CLOSED CONFORMATIONS: IMPLICATIONS FOR SUBSTRATE-INDUCED FIT CONFORMATIONAL CHANGES | ASKHA (ACETATE AND SUGAR KINASES, HSC70, ACTIN) SUPERFAMILY, BUTYRATE KINASE, ACETATE KINASE, ISOBUTYRATE KINASE, TWO SIMILAR DOMAINS, BUTYRATE, ISOBUTYRATE, ENZYME MECHANISM, TRANSFERASE
3zx0:A (THR124) to (SER141) NTPDASE1 IN COMPLEX WITH HEPTAMOLYBDATE | DOMAIN ROTATION, HYDROLASE, POLYOXOMETALLATE, METAL CLUSTER, PURINERGIC SIGNALING
3zx0:B (THR124) to (SER141) NTPDASE1 IN COMPLEX WITH HEPTAMOLYBDATE | DOMAIN ROTATION, HYDROLASE, POLYOXOMETALLATE, METAL CLUSTER, PURINERGIC SIGNALING
3zx2:B (THR124) to (SER141) NTPDASE1 IN COMPLEX WITH DECAVANADATE | DOMAIN ROTATION, HYDROLASE, POLYOXOMETALLATE, METAL CLUSTER, PURINERGIC SIGNALING N
5c71:D (ARG69) to (GLU80) THE STRUCTURE OF ASPERGILLUS ORYZAE A-GLUCURONIDASE COMPLEXED WITH GLYCYRRHETINIC ACID MONOGLUCURONIDE | BETA-GLUCURONIDASE; GLYCYRRHETINIC ACID MONOGLUCURONIDE, HYDROLASE
2nmz:B (ASN183) to (GLY194) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A INHIBITOR SAQUINAVIR | HIV-1 PROTEASE, MUTANT, V82A, DIMER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2nnp:B (ASN183) to (GLY194) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT I84V WITH A INHIBITOR SAQUINAVIR | HIV-1 PROTEASE, MUTANT, I84V, DIMER, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4o0z:B (THR468) to (ALA480) STRUCTURAL AND BIOCHEMICAL ANALYSES OF THE CATALYSIS AND POTENCY IMPACT OF INHIBITOR PHOSPHORIBOSYLATION BY HUMAN NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4o10:B (THR468) to (ALA480) STRUCTURAL AND BIOCHEMICAL ANALYSES OF THE CATALYSIS AND POTENCY IMPACT OF INHIBITOR PHOSPHORIBOSYLATION BY HUMAN NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4o18:B (THR468) to (ALA480) STRUCTURAL BASIS FOR RESISTANCE TO DIVERSE CLASSES OF NAMPT INHIBITORS | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1l1l:A (THR546) to (GLY558) CRYSTAL STRUCTURE OF B-12 DEPENDENT (CLASS II) RIBONUCLEOTIDE REDUCTASE | 10-STRANDED ALPHA-BETA BARREL, CENTRAL FINGER LOOP, OXIDOREDUCTASE
1l1l:D (THR546) to (GLY558) CRYSTAL STRUCTURE OF B-12 DEPENDENT (CLASS II) RIBONUCLEOTIDE REDUCTASE | 10-STRANDED ALPHA-BETA BARREL, CENTRAL FINGER LOOP, OXIDOREDUCTASE
4o28:B (THR468) to (ALA480) STRUCTURAL BASIS FOR RESISTANCE TO DIVERSE CLASSES OF NAMPT INHIBITORS | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3jrk:A (VAL16) to (GLN36) A PUTATIVE TAGATOSE 1,6-DIPHOSPHATE ALDOLASE FROM STREPTOCOCCUS PYOGENES | APC80109.1, STREPTOCOCCUS PYOGENES M1 GAS, TAGATOSE, 1,6-DIPHOSPHATE ALDOLASE, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, LACTOSE METABOLISM, LYASE
2ylf:A (ASP38) to (TYR49) CRYSTAL STRUCTURE OF THE HUMAN SPIR-1 KIND DOMAIN | ACTIN-BINDING PROTEIN, ACTIN POLYMERIZATION, SPIR, KINASE
3js3:A (ILE45) to (ASN58) CRYSTAL STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE (AROD) FROM CLOSTRIDIUM DIFFICILE WITH COVALENT REACTION INTERMEDIATE | TYPE I 3-DEHYDROQUINATE DEHYDRATASE, AROD, COVALENT REACTION INTERMEDIATE, AMINO-ACID BIOSYNTHESIS, AROMATIC AMINO ACID BIOSYNTHESIS, LYASE, SCHIFF BASE, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
3js3:C (ILE45) to (ASN58) CRYSTAL STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE (AROD) FROM CLOSTRIDIUM DIFFICILE WITH COVALENT REACTION INTERMEDIATE | TYPE I 3-DEHYDROQUINATE DEHYDRATASE, AROD, COVALENT REACTION INTERMEDIATE, AMINO-ACID BIOSYNTHESIS, AROMATIC AMINO ACID BIOSYNTHESIS, LYASE, SCHIFF BASE, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
2nuj:A (THR8) to (SER19) CRYSTAL STRUCTURE OF THIOESTERASE SUPERFAMILY (YP_509914.1) FROM JANNASCHIA SP. CCS1 AT 2.00 A RESOLUTION | YP_509914.1, THIOESTERASE SUPERFAMILY, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, HYDROLASE
1l6w:E (VAL25) to (LYS36) FRUCTOSE-6-PHOSPHATE ALDOLASE | ALPHA-BETA BARREL, DOMAIN SWAPPING, LYASE
3jvy:B (ASN183) to (GLY194) HIV-1 PROTEASE MUTANT G86A WITH DARUNAVIR | HIV-1 PROTEASE, MUTANT G86A, INHIBITOR, DARUNAVIR, AIDS, ASPARTYL PROTEASE, HYDROLASE, METAL-BINDING
4a0w:H (ALA3) to (LEU30) MODEL BUILT AGAINST SYMMETRY-FREE CRYO-EM MAP OF TRIC-ADP-ALFX | CHAPERONE, CHAPERONIN, PROTEIN FOLDING
4a11:A (LYS244) to (SER256) STRUCTURE OF THE HSDDB1-HSCSA COMPLEX | DNA BINDING PROTEIN, DNA DAMAGE REPAIR
4a21:A (ASP47) to (SER61) STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FRUCTOSE 1,6- BISPHOSPHATE ALDOLASE BOUND TO SULFATE | HYDROLASE, FBP ALDOLASE, CLASS II, INHIBITOR, LYASE, LYASE-LYASE INHIBITOR COMPLEX
4a21:B (ASP47) to (SER61) STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FRUCTOSE 1,6- BISPHOSPHATE ALDOLASE BOUND TO SULFATE | HYDROLASE, FBP ALDOLASE, CLASS II, INHIBITOR, LYASE, LYASE-LYASE INHIBITOR COMPLEX
4a21:D (ASP47) to (GLY60) STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FRUCTOSE 1,6- BISPHOSPHATE ALDOLASE BOUND TO SULFATE | HYDROLASE, FBP ALDOLASE, CLASS II, INHIBITOR, LYASE, LYASE-LYASE INHIBITOR COMPLEX
4a22:B (ASP47) to (SER61) STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE BOUND TO N-(4-HYDROXYBUTYL)-GLYCOLOHYDROXAMIC ACID BIS-PHOSPHATE | LYASE, LYASE-INHIBITOR COMPLEX
5cgg:F (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA5-G48C MUTANT IN COMPLEX WITH ALPHA- CHLOROACETAMIDE 1 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
5cgg:T (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA5-G48C MUTANT IN COMPLEX WITH ALPHA- CHLOROACETAMIDE 1 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
2yrb:A (GLU604) to (SER624) SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN FROM HUMAN KIAA1005 PROTEIN | BETA SANDWICH, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
5cgh:F (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA5-G48C MUTANT IN COMPLEX WITH ALPHA- CHLOROACETAMIDE 5 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
5cgh:T (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA5-G48C MUTANT IN COMPLEX WITH ALPHA- CHLOROACETAMIDE 5 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
2yvw:A (PHE89) to (MET99) CRYSTAL STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE FROM AQUIFEX AEOLICUS VF5 | PEPTIDOGLYCAN, TRANSFERASE, UDP-N-ACETYLGLUCOSAMINE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2ywq:A (LEU11) to (GLN32) CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS PROTEIN Y N-TERMINAL DOMAIN | SIGMA-54 MODULATION PROTEIN FAMILY, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, RIBOSOMAL PROTEIN
2ywq:B (LEU11) to (GLN32) CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS PROTEIN Y N-TERMINAL DOMAIN | SIGMA-54 MODULATION PROTEIN FAMILY, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, RIBOSOMAL PROTEIN
2ywq:C (LEU11) to (GLN32) CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS PROTEIN Y N-TERMINAL DOMAIN | SIGMA-54 MODULATION PROTEIN FAMILY, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, RIBOSOMAL PROTEIN
2nxl:B (ASN83) to (GLY94) STRUCTURE OF HIV-1 PROTEASE D25N COMPLEXED WITH THE RT-RH ANALOGUE PEPTIDE GLY-ALA-GLU-VAL-PHE*TYR-VAL-ASP-GLY-ALA | PEPTIDE DESIGN; MOLECULAR DYNAMICS; HIV PROTEASE; SUBSTRATE RECOGNITION; CALORIMETRY, HYDROLASE/HYDROLASE SUBSTRATE COMPLEX
2nxm:A (ASN83) to (GLY94) STRUCTURE OF HIV-1 PROTEASE D25N COMPLEXED WITH THE RT-RH ANALOGUE PEPTIDE GLY-ALA-GLN-THR-PHE*TYR-VAL-ASP-GLY-ALA | PEPTIDE DESIGN; MOLECULAR DYNAMICS; HIV PROTEASE; SUBSTRATE RECOGNITION; CALORIMETRY, HYDROLASE/HYDROLASE SUBSTRATE COMPLEX
3k1f:E (PHE60) to (PRO73) CRYSTAL STRUCTURE OF RNA POLYMERASE II IN COMPLEX WITH TFIIB | RNA POLYMERASE II, TFIIB, TRANSCRIPTION FACTOR, TRANSCRIPTION INITIATION, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, METAL-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSCRIPTION, TRANSFERASE, ZINC-FINGER, DNA DAMAGE, DNA REPAIR, MRNA PROCESSING, INITIATION FACTOR
1li5:A (ASP109) to (ILE118) CRYSTAL STRUCTURE OF CYSTEINYL-TRNA SYNTHETASE | TRNA SYNTHETASE, CYSTEINE, E.COLI, LIGASE
4a3e:E (PHE60) to (PRO73) RNA POLYMERASE II INITIAL TRANSCRIBING COMPLEX WITH A 5NT DNA-RNA HYBRID AND SOAKED WITH AMPCPP | TRANSCRIPTION, TRANSCRIPTION INITIATION
4a3i:E (PHE60) to (PRO73) RNA POLYMERASE II BINARY COMPLEX WITH DNA | TRANSCRIPTION, TRANSCRIPTION INITIATION
2z4o:B (ASN183) to (GLY194) WILD TYPE HIV-1 PROTEASE WITH POTENT ANTIVIRAL INHIBITOR GRL-98065 | HIV-1, WILD TYPE PROTEASE, PROTEASE INHIBITOR, HYDROLASE
4a3j:E (PHE60) to (PRO73) RNA POLYMERASE II INITIAL TRANSCRIBING COMPLEX WITH A 2NT DNA-RNA HYBRID AND SOAKED WITH GMPCPP | TRANSCRIPTION, TRANSCRIPTION INITIATION
5cnq:A (LEU33) to (ALA49) CRYSTAL STRUCTURE OF THE HOLLIDAY JUNCTION-RESOLVING ENZYME GEN1 (WT) IN COMPLEX WITH PRODUCT DNA, MG2+ AND MN2+ IONS | GEN1, 4-WAY HOLIDAY JUNCTION, RESOLVASE, DNA DAMAGE REPAIR, REPLICATION
2o2p:A (CYS451) to (PHE472) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE | ALDEHYDE DEHYDROGENASE, FDH, OXIDOREDUCTASE
2o2p:B (CYS451) to (PHE472) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE | ALDEHYDE DEHYDROGENASE, FDH, OXIDOREDUCTASE
2o2p:C (VAL453) to (PHE472) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE | ALDEHYDE DEHYDROGENASE, FDH, OXIDOREDUCTASE
2o2p:D (CYS451) to (PHE472) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE | ALDEHYDE DEHYDROGENASE, FDH, OXIDOREDUCTASE
2o2r:B (CYS451) to (PHE472) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE IN COMPLEX WITH NADPH | ALDEHYDE DEHYDROGENASE, FDH, OXIDOREDUCTASE
4a3l:E (PHE60) to (PHE72) RNA POLYMERASE II INITIAL TRANSCRIBING COMPLEX WITH A 7NT DNA-RNA HYBRID AND SOAKED WITH AMPCPP | TRANSCRIPTION, TRANSCRIPTION INITIATION
2z80:A (ASN89) to (LEU99) CRYSTAL STRUCTURE OF THE TLR1-TLR2 HETERODIMER INDUCED BY BINDING OF A TRI-ACYLATED LIPOPEPTIDE | TLR2, LIPOPEPTIDE, INNATE IMMUNITY, GLYCOPROTEIN, IMMUNE RESPONSE, INFLAMMATORY RESPONSE, LEUCINE-RICH REPEAT, MEMBRANE, RECEPTOR, TRANSMEMBRANE, IMMUNE SYSTEM
4a3m:E (PHE60) to (PRO73) RNA POLYMERASE II INITIAL TRANSCRIBING COMPLEX WITH A 4NT DNA-RNA HYBRID AND SOAKED WITH AMPCPP | TRANSCRIPTION, TRANSCRIPTION INITIATION
2o4k:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K) IN COMPLEX WITH ATAZANAVIR | PROTEASE COMPLEX, VIRAL PROTEIN
2o4l:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, I50V) IN COMPLEX WITH TIPRANAVIR | PROTEASE, VIRAL PROTEIN
2o4l:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, I50V) IN COMPLEX WITH TIPRANAVIR | PROTEASE, VIRAL PROTEIN
2o4p:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K) IN COMPLEX WITH TIPRANAVIR | PROTEASE, VIRAL PROTEIN
4a4c:A (HIS360) to (GLY375) STRUCTURE OF PHOSPHOTYR371-C-CBL-UBCH5B-ZAP-70 COMPLEX | LIGASE-TRANSFERASE COMPLEX
2o56:B (PHE223) to (ILE236) CRYSTAL STRUCTURE OF A MEMBER OF THE ENOLASE SUPERFAMILY FROM SALMONELLA TYPHIMURIUM | DEHYDRATASE, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI- 2, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, UNKNOWN FUNCTION
2o56:F (PHE223) to (ILE236) CRYSTAL STRUCTURE OF A MEMBER OF THE ENOLASE SUPERFAMILY FROM SALMONELLA TYPHIMURIUM | DEHYDRATASE, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI- 2, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, UNKNOWN FUNCTION
2o56:G (PHE223) to (ILE236) CRYSTAL STRUCTURE OF A MEMBER OF THE ENOLASE SUPERFAMILY FROM SALMONELLA TYPHIMURIUM | DEHYDRATASE, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI- 2, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, UNKNOWN FUNCTION
4a55:A (VAL484) to (VAL500) CRYSTAL STRUCTURE OF P110ALPHA IN COMPLEX WITH ISH2 OF P85ALPHA AND THE INHIBITOR PIK-108 | TRANSFERASE, ONCOGENE, LIPID KINASE, MEMBRANE BINDING, CANCER MUTATIONS, TUMOURS, GROWTH FACTOR SIGNALLING, PI3-KINASE INHIBITOR, NON-ATP COMPETITIVE LIGAND BINDING SITE, STRUCTURE-ACTIVITY RELATIONSHIP, ENZYME REGULATION
2z8y:M (ASN426) to (LYS437) XENON-BOUND STRUCTURE OF BIFUNCTIONAL CARBON MONOXIDE DEHYDROGENASE/ACETYL-COA SYNTHASE(CODH/ACS) FROM MOORELLA THERMOACETICA | XENON, CARBON MONOXIDE (CO) CHANNEL, NICKEL-IRON-SULFUR (NI-FE-S) CLUSTER, NICKEL-COPPER-IRON-SULFUR (NI-CU-FE-S) CLUSTER, HELICAL DOMAIN, ROSSMANN FOLD, CLOSTRIDIUM THERMOACETICUM, WOOD-LJUNDAHL PATHWAY, CARBON DIOXIDE FIXATION, ELECTRON TRANSPORT, METAL-BINDING, OXIDOREDUCTASE, TRANSPORT, TRANSFERASE, OXIDOREDUCTASE-TRANSFERASE COMPLEX
1lv1:A (ASN1083) to (GLY1094) CRYSTAL STRUCTURE ANALYSIS OF THE NON-ACTIVE SITE MUTANT OF TETHERED HIV-1 PROTEASE TO 2.1A RESOLUTION | BETA-RIBBON FLAP, HYDROLASE
1xkw:A (SER82) to (GLN94) PYOCHELIN OUTER MEMBRANE RECEPTOR FPTA FROM PSEUDOMONAS AERUGINOSA | TONB DEPENDENT RECEPTOR, MEMBRANE PROTEIN
1xlj:B (ILE210) to (MET222) MECHANISM FOR ALDOSE-KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE INVOLVING RING OPENING FOLLOWED BY A 1,2-HYDRIDE SHIFT | ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)
2o64:A (PRO125) to (GLU135) CRYSTAL STRUCTURE OF PIM1 WITH QUERCETAGETIN | PIM1, QUERCETAGETIN, TRANSFERASE
4ojy:A (HIS374) to (VAL406) 3D STRUCTURE OF THE E323A CATALYTIC MUTANT OF GAN42B, A GH42 BETA- GALACTOSIDASE FROM G. STEAROTHERMOPHILUS | BETA-GALACTOSIDASE. GAN42B, BETA-GALACTOSIDASE, GH42, GAN42B, HOMO- TRIMER, HYDOLASE, CARBOHYDRATE/SUGAR BINDING, INTRACELLULAR, HYDROLASE
3k8s:A (GLN345) to (LEU356) CRYSTAL STRUCTURE OF PPARG IN COMPLEX WITH T2384 | PPARGAMMA, LIGAND BINDING POCKET, LIGAND, DIABETIC, ACTIVATOR, ALTERNATIVE SPLICING, DIABETES MELLITUS, DISEASE MUTATION, DNA-BINDING, METAL-BINDING, NUCLEUS, OBESITY, PHOSPHOPROTEIN, POLYMORPHISM, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC, ZINC-FINGER, LBD AND LIGAND BINDING DOMAIN
2o7i:A (GLY80) to (GLU97) THE X-RAY CRYSTAL STRUCTURE OF A THERMOPHILIC CELLOBIOSE BINDING PROTEIN BOUND WITH CELLOBIOSE | PERIPLASMIC BINDING PROTEIN, CELLULOSE, THERMOPHILIC PROTEINS, CELLOBIOSE BINDING PROTEIN, SUGAR BINDING PROTEIN
1m1n:D (ALA148) to (GLY159) NITROGENASE MOFE PROTEIN FROM AZOTOBACTER VINELANDII | ATOMIC RESOLUTION, FEMO COFACTOR, NITROGEN FIXATION, CENTRAL NITROGEN LIGAND, OXIDOREDUCTASE
2zep:A (LEU243) to (GLY282) CRYSTAL STRUCTURE OF THE HUMAN GLUTAMINYL CYCLASE MUTANT H319L AT 2.1 ANGSTROM RESOLUTION | HYDROGEN BOND NETWORK, GLUTAMINYL CYCLASE, PYROGLUTAMATE, SITE- DIRECTED MUTAGENESIS, PROTON TRANSFER, ACYLTRANSFERASE, GLYCOPROTEIN, METAL-BINDING, TRANSFERASE
2zfk:A (ALA9) to (ASP23) CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN DURING MG RELEASE: MG-RELEASING TRANSITION-2 | KINESIN, ALPHA AND BETA PROTEIN, ENZYME, ATPASE, P-LOOP, MOTOR PROTEIN, ATP-BINDING, COILED COIL, MICROTUBULE, NUCLEOTIDE-BINDING, TRANSPORT PROTEIN
1m45:A (GLY135) to (LEU147) CRYSTAL STRUCTURE OF MLC1P BOUND TO IQ2 OF MYO2P, A CLASS V MYOSIN | PROTEIN-PEPTIDE COMPLEX, IQ MOTIF, MYOSIN LIGHT CHAIN, CELL CYCLE PROTEIN
3kdb:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, L33I, L63I) IN COMPLEX WITH KNI-10006 | VIRAL PROTEIN, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3kdd:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, L33I, L63I) IN COMPLEX WITH KNI-10265 | VIRAL PROTEIN, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3kdd:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, L33I, L63I) IN COMPLEX WITH KNI-10265 | VIRAL PROTEIN, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3kdk:A (ILE610) to (PHE623) STRUCTURE OF THE C-TERMINAL DOMAIN OF BACILLUS SUBTILIS MUTL BOUND TO ZN2+ | MISMATCH REPAIR, MUTL, ENDONUCLEASE, ZN-BINDING PROTEIN, DNA DAMAGE, DNA REPAIR, HYDROLASE
3kdk:B (ILE610) to (MET622) STRUCTURE OF THE C-TERMINAL DOMAIN OF BACILLUS SUBTILIS MUTL BOUND TO ZN2+ | MISMATCH REPAIR, MUTL, ENDONUCLEASE, ZN-BINDING PROTEIN, DNA DAMAGE, DNA REPAIR, HYDROLASE
5cve:B (ASP130) to (HIS140) CRYSTAL STRUCTURE OF HUMAN NRMT1 IN COMPLEX WITH DIMETHYLATED FLY H2B PEPTIDE AND SAH | N-TERMINAL METHYLTRANSFERASE, TRANSFERASE-PEPTIDE COMPLEX
2zk6:B (GLN345) to (LEU356) HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA LIGAND BINDING DOMAIN COMPLEXED WITH C8-BODIPY | ANTI PARALLEL HELIX SANDWICH, ACTIVATOR, DIABETES MELLITUS, DISEASE MUTATION, DNA-BINDING, METAL-BINDING, NUCLEUS, OBESITY, PHOSPHOPROTEIN, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC-FINGER
1xtt:C (PRO2) to (ASP20) SULFOLOBUS SOLFATARICUS URACIL PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH URIDINE 5'-MONOPHOSPHATE (UMP) | TETRAMER, TYPE 1 PHOSPHORIBOSYLTRANSFERASE, UMP COMPLEX
1xtu:A (PRO2) to (ASP20) SULFOLOBUS SOLFATARICUS URACIL PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH URIDINE 5'-MONOPHOSPHATE (UMP) AND CYTIDINE 5'-TRIPHOSPHATE (CTP) | TETRAMER, TYPE 1 PHOSPHORIBOSYLTRANSFERASE, UMP AND CTP COMPLEX
1xtu:B (PRO2) to (ASP20) SULFOLOBUS SOLFATARICUS URACIL PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH URIDINE 5'-MONOPHOSPHATE (UMP) AND CYTIDINE 5'-TRIPHOSPHATE (CTP) | TETRAMER, TYPE 1 PHOSPHORIBOSYLTRANSFERASE, UMP AND CTP COMPLEX
1xtu:C (PRO2) to (ASP20) SULFOLOBUS SOLFATARICUS URACIL PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH URIDINE 5'-MONOPHOSPHATE (UMP) AND CYTIDINE 5'-TRIPHOSPHATE (CTP) | TETRAMER, TYPE 1 PHOSPHORIBOSYLTRANSFERASE, UMP AND CTP COMPLEX
1xtu:D (PRO2) to (ASP20) SULFOLOBUS SOLFATARICUS URACIL PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH URIDINE 5'-MONOPHOSPHATE (UMP) AND CYTIDINE 5'-TRIPHOSPHATE (CTP) | TETRAMER, TYPE 1 PHOSPHORIBOSYLTRANSFERASE, UMP AND CTP COMPLEX
1xtu:E (PRO2) to (ASP20) SULFOLOBUS SOLFATARICUS URACIL PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH URIDINE 5'-MONOPHOSPHATE (UMP) AND CYTIDINE 5'-TRIPHOSPHATE (CTP) | TETRAMER, TYPE 1 PHOSPHORIBOSYLTRANSFERASE, UMP AND CTP COMPLEX
1xtu:F (PRO2) to (ASP20) SULFOLOBUS SOLFATARICUS URACIL PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH URIDINE 5'-MONOPHOSPHATE (UMP) AND CYTIDINE 5'-TRIPHOSPHATE (CTP) | TETRAMER, TYPE 1 PHOSPHORIBOSYLTRANSFERASE, UMP AND CTP COMPLEX
1xtu:G (PRO2) to (ASP20) SULFOLOBUS SOLFATARICUS URACIL PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH URIDINE 5'-MONOPHOSPHATE (UMP) AND CYTIDINE 5'-TRIPHOSPHATE (CTP) | TETRAMER, TYPE 1 PHOSPHORIBOSYLTRANSFERASE, UMP AND CTP COMPLEX
1xtu:H (PRO2) to (ASP20) SULFOLOBUS SOLFATARICUS URACIL PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH URIDINE 5'-MONOPHOSPHATE (UMP) AND CYTIDINE 5'-TRIPHOSPHATE (CTP) | TETRAMER, TYPE 1 PHOSPHORIBOSYLTRANSFERASE, UMP AND CTP COMPLEX
3kf0:B (ASN83) to (GLY94) HIV PROTEASE WITH FRAGMENT 4D9 BOUND | PROTEASE, TL-3 INHIBITOR, FRAGMENT HIT, ASPARTYL PROTEASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
1xtv:A (PRO2) to (ASP20) SULFOLOBUS SOLFATARICUS URACIL PHOSPHORIBOSYLTRANSFERASE WITH URIDINE 5'-MONOPHOSPHATE (UMP) BOUND TO HALF OF THE SUBUNITS | TETRAMER, TYPE 1 PHOSPHORIBOSYLTRANSFERASE, UMP COMPLEX
1xtv:E (PRO2) to (ASP20) SULFOLOBUS SOLFATARICUS URACIL PHOSPHORIBOSYLTRANSFERASE WITH URIDINE 5'-MONOPHOSPHATE (UMP) BOUND TO HALF OF THE SUBUNITS | TETRAMER, TYPE 1 PHOSPHORIBOSYLTRANSFERASE, UMP COMPLEX
1xu5:A (PHE359) to (ASN375) SOLUBLE METHANE MONOOXYGENASE HYDROXYLASE-PHENOL SOAKED | METHANE, SUBSTRATE BINDING, CAVITIES, FOUR-HELIX BUNDLE, DIIRON, OXIDOREDUCTASE
4or8:A (ILE143) to (LEU167) CRYSTAL STRUCTURE OF MARBURG VIRUS VP24 | MARBURG, VP24, PYRAMIDAL FOLD, PROTEIN, EBOLA, VIRUS, VIRAL, VIRAL PROTEIN
1xvb:A (PHE359) to (ASN375) SOLUBLE METHANE MONOOXYGENASE HYDROXYLASE: 6-BROMOHEXANOL SOAKED STRUCTURE | METHANE, DIIRON, CAVITIES, PRODUCTS, FOUR-HELIX BUNDLE, OXIDOREDUCTASE
3kfl:A (ASN296) to (LYS320) LEISHMANIA MAJOR METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH METHIONYLADENYLATE AND PYROPHOSPHATE | LEISHMANIA, PARASITE, AMINOACYL-TRNA SYNTHETASE, TRNA LIGASE, AARS, METRS, METHIONINE, TRANSLATION, ATP-BINDING, NUCLEOTIDE-BINDING, STRUCTURAL GENOMICS, MSGPP, LIGASE, MEDICAL STRUCTURAL GENOMICS OF PATHOGENIC PROTOZOA
2zno:A (GLN345) to (LEU356) HUMAN PPAR GAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH A SYNTHETIC AGONIST TIPP703 | NUCLEAR RECEPTOR, PROTEIN-LIGAND COMPLEX, PPAR, ACTIVATOR, DIABETES MELLITUS, DISEASE MUTATION, DNA-BINDING, METAL-BINDING, NUCLEUS, OBESITY, PHOSPHOPROTEIN, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC-FINGER
3kfn:A (ASN83) to (GLY94) HIV PROTEASE (PR) WITH INHIBITOR TL-3 AND FRAGMENT HIT 4D9 BY SOAKING | HIV-1, PROTEASE, EXO SITE, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3kfn:B (ASN83) to (GLY94) HIV PROTEASE (PR) WITH INHIBITOR TL-3 AND FRAGMENT HIT 4D9 BY SOAKING | HIV-1, PROTEASE, EXO SITE, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1xvc:B (PHE359) to (ASN375) SOLUBLE METHANE MONOOXYGENASE HYDROXYLASE: 8-BROMOOCTANOL SOAKED STRUCTURE | METHANE, DIIRON, FOUR-HELIX BUNDLE, PRODUCT BINDING, CAVITY, OXIDOREDUCTASE
3kfr:A (ASN83) to (GLY94) HIV PROTEASE (PR) DIMER WITH INHIBITOR TL-3 BOUND AND FRAGMENT 1F1 IN THE OUTSIDE/TOP OF FLAP | HIV-1, PROTEASE, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1xvd:B (PHE359) to (ASN375) SOLUBLE METHANE MONOOXYGENASE HYDROXYLASE: 4-FLUOROPHENOL SOAKED STRUCTURE | METHANE, FOUR-HELIX BUNDLE, DIIRON, PRODUCT BINDING, CAVITIES, OXIDOREDUCTASE
3kfu:F (VAL273) to (LEU287) CRYSTAL STRUCTURE OF THE TRANSAMIDOSOME | ASPRS, GATCAB, ATP-BINDING, AMINOACYL-TRNA SYNTHETASE, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, LIGASE-RNA COMPLEX
1xve:B (PHE359) to (ASN375) SOLUBLE METHANE MONOOXYGENASE HYDROXYLASE: 3-BROMO-3- BUTENOL SOAKED STRUCTURE | METHANE, DIIRON, FOUR-HELIX BUNDLE, PRODUCT BINDING, CAVITIES, OXIDOREDUCTASE
4aau:A (ASP5) to (LEU31) ATP-TRIGGERED MOLECULAR MECHANICS OF THE CHAPERONIN GROEL | CHAPERONE
4aau:B (ASP5) to (LEU31) ATP-TRIGGERED MOLECULAR MECHANICS OF THE CHAPERONIN GROEL | CHAPERONE
4aau:C (ASP5) to (LEU31) ATP-TRIGGERED MOLECULAR MECHANICS OF THE CHAPERONIN GROEL | CHAPERONE
4aau:D (ASP5) to (LEU31) ATP-TRIGGERED MOLECULAR MECHANICS OF THE CHAPERONIN GROEL | CHAPERONE
4aau:E (ASP5) to (LEU31) ATP-TRIGGERED MOLECULAR MECHANICS OF THE CHAPERONIN GROEL | CHAPERONE
4aau:F (ASP5) to (LEU31) ATP-TRIGGERED MOLECULAR MECHANICS OF THE CHAPERONIN GROEL | CHAPERONE
4aau:G (ASP5) to (LEU31) ATP-TRIGGERED MOLECULAR MECHANICS OF THE CHAPERONIN GROEL | CHAPERONE
5czs:D (SER160) to (SER171) NEISSERIA MENINGITIDIS 3 DEXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE GLU98ALA VARIANT REGULATED | REGULATED DAH7PS, TRANSFERASE
5d05:B (SER160) to (SER171) NEISSERIA MENINGITIDIS 3 DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE LYS107ALA VARIANT REGULATED | DAH7PS, ALLOSTERY, TRANSFERASE
5d05:C (SER160) to (GLN172) NEISSERIA MENINGITIDIS 3 DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE LYS107ALA VARIANT REGULATED | DAH7PS, ALLOSTERY, TRANSFERASE
4ow0:A (LYS54) to (HIS74) X-RAY STRUCTURAL AND BIOLOGICAL EVALUATION OF A SERIES OF POTENT AND HIGHLY SELECTIVE INHIBITORS OF HUMAN CORONAVIRUS PAPAIN-LIKE PROTEASES | COV, CORONAVIRUS, HCOV, HUMAN CORONAVIRUS, SARS, SEVERE ACUTE RESPIRATORY SYNDROME, MERS, MIDDLE EAST RESPIRATORY SYNDROME, PLPRO, PAPAIN-LIKE PROTEASE; INHIBITOR, COMPLEX, DUB, DEUBIQUITINATING ENZYME, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5d09:D (SER160) to (GLN172) NEISSERIA MENINGITIDIS 3 DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE PHE211ALA VARIANT | DAH7PS, ALLOSTERY, TRANSFERASE
4ox2:A (MET173) to (GLY185) I45T CYTOSOLIC PHOSPHOENOLPYRUVATE CARBOXYKINASE IN COMPLEX WITH BETA- SULFOPYRUVATE AND GTP | KINASE, GLUCONEOGENESIS, LYASE
4ox2:B (MET173) to (GLY185) I45T CYTOSOLIC PHOSPHOENOLPYRUVATE CARBOXYKINASE IN COMPLEX WITH BETA- SULFOPYRUVATE AND GTP | KINASE, GLUCONEOGENESIS, LYASE
3kkk:A (PHE150) to (ASN176) Y92C CATALYTIC RESIDUE MUTANT OF PHOSPHOGLYCERATE MUTASE FROM PLASMODIUM FALCIPARUM | PGAM, GLYCOLYSIS, MALARIA, STRUCTURAL GENOMICS, MEDICAL STRUCTURAL GENOMICS OF PATHOGENIC PROTOZOA, MSGPP, ISOMERASE
5d0s:T (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA5-D166N MUTANT IN COMPLEX WITH CARFILZOMIB | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
1mhy:D (ALA359) to (ASN375) METHANE MONOOXYGENASE HYDROXYLASE | OXIDOREDUCTASE, MONOOXYGENASE, NADP, ONE-CARBON METABOLISM
1mhz:D (ALA359) to (ASN375) METHANE MONOOXYGENASE HYDROXYLASE | OXIDOREDUCTASE, MONOOXYGENASE, NADP, ONE-CARBON METABOLISM
1mj9:A (ILE402) to (LYS419) CRYSTAL STRUCTURE OF YEAST ESA1(C304S) MUTANT COMPLEXED WITH COENZYME A | ESA1, HAT, HISTONE ACETYLTRANSFERASE, MYST, TRANSFERASE
1mjb:A (ILE402) to (ALA418) CRYSTAL STRUCTURE OF YEAST ESA1 HISTONE ACETYLTRANSFERASE E338Q MUTANT COMPLEXED WITH ACETYL COENZYME A | ESA1, HISTONE ACETYLTRANSFERASES, HAT, MYST, TRANSFERASE
4p1g:A (GLY565) to (ILE576) CRYSTAL STRUCTURE OF THE BATEMAN DOMAIN OF MURINE MAGNESIUM TRANSPORTER CNNM2 BOUND TO AMP | MAGNESIUM HOMEOSTASIS, TRANSPORT, HYPOMAGNESEMIA, RARE DISEASES, ACDP, CYCLIN M, TRANSPORT PROTEIN
4p1o:B (GLY565) to (ILE576) CRYSTAL STRUCTURE OF THE BATEMAN DOMAIN OF MURINE MAGNESIUM TRANSPORTER CNNM2 BOUND TO ATP-MG | MAGNESIUM HOMEOSTASIS, TRANSPORT, HYPOMAGNESEMIA, RARE DISEASES, ACDP, CYCLIN M, TRANSPORT PROTEIN
3km9:A (ALA297) to (SER311) STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH THE C-TERMINAL BETA-GRASP DOMAIN OF SSL7 | OB-FOLD, BETA-GRASP DOMAIN, FN3 DOMAIN, CLEAVAGE ON PAIR OF BASIC RESIDUES, COMPLEMENT ALTERNATE PATHWAY, COMPLEMENT PATHWAY, CYTOLYSIS, DISULFIDE BOND, GLYCOPROTEIN, IMMUNE RESPONSE, INFLAMMATORY RESPONSE, INNATE IMMUNITY, MEMBRANE ATTACK COMPLEX, SECRETED, IMMUNE SYSTEM
3km9:B (ALA297) to (SER311) STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH THE C-TERMINAL BETA-GRASP DOMAIN OF SSL7 | OB-FOLD, BETA-GRASP DOMAIN, FN3 DOMAIN, CLEAVAGE ON PAIR OF BASIC RESIDUES, COMPLEMENT ALTERNATE PATHWAY, COMPLEMENT PATHWAY, CYTOLYSIS, DISULFIDE BOND, GLYCOPROTEIN, IMMUNE RESPONSE, INFLAMMATORY RESPONSE, INNATE IMMUNITY, MEMBRANE ATTACK COMPLEX, SECRETED, IMMUNE SYSTEM
1mo9:B (LYS176) to (GLU207) NADPH DEPENDENT 2-KETOPROPYL COENZYME M OXIDOREDUCTASE/CARBOXYLASE COMPLEXED WITH 2-KETOPROPYL COENZYME M | NUCLEOTIDE BINDING MOTIFS, NUCLEOTIDE BINDING DOMAIN, OXIDOREDUCTASE
1y82:B (ILE66) to (GLY91) CONSERVED HYPOTHETICAL PROTEIN PFU-367848-001 FROM PYROCOCCUS FURIOSUS | STRUCTURAL GENOMICS, CONSERVED HYPOTHETICAL PROTEIN, SECSG, PSI, SOUTHEAST COLLABORATORY FOR STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PYROCOCCUS FURIOSUS, PFU-367848-001, HYPERTHERMOPHILE, UNKNOWN FUNCTION
4p71:B (ALA491) to (GLY506) APO PHERS FROM P. AEURIGINOSA | PHENYLALANINE TRNA SYNTHETASE, PHERS, LIGASE
4p74:A (ALA491) to (GLY506) PHERS IN COMPLEX WITH COMPOUND 3A | PHENYLALANINE TRNA SYNTHETASE, PHERS, LIGASE-LIGASE INHIBITOR COMPLEX
4p75:A (ALA491) to (GLY506) PHERS IN COMPLEX WITH COMPOUND 4A | PHENYLALANINE TRNA SYNTHETASE, PHERS, LIGASE-LIGASE INHIBITOR COMPLEX
1mrw:A (ASN83) to (GLY94) STRUCTURE OF HIV PROTEASE (MUTANT Q7K L33I L63I) COMPLEXED WITH KNI- 577 | HIV, KNI-577, PROTEASE, DRUG TARGET, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1mrx:B (ASN83) to (GLY94) STRUCTURE OF HIV PROTEASE (MUTANT Q7K L33I L63I V82F I84V ) COMPLEXED WITH KNI-577 | HIV, KNI-577, PROTEASE, DRUG TARGET, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1msn:B (ASN83) to (GLY94) THE HIV PROTEASE (MUTANT Q7K L33I L63I V82F I84V) COMPLEXED WITH KNI- 764 (AN INHIBITOR) | HIV, KNI-764, PROTEASE, DRUG TARGET, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1msm:B (ASN83) to (GLY94) THE HIV PROTEASE (MUTANT Q7K L33I L63I) COMPLEXED WITH KNI-764 (AN INHIBITOR) | HIV, KNI-764, PROTEASE, DRUG TARGET, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5d6d:A (GLN342) to (ASN361) CRYSTAL STRUCTURE OF GASDALIE IGG1 FC IN COMPLEX WITH FCGRIIIA | ADCC, IMMUNE SYSTEM, IGG
3kr3:L (THR110) to (GLY129) CRYSTAL STRUCTURE OF IGF-II ANTIBODY COMPLEX | ANTIBODY-TARGET COMPLEX, CARBOHYDRATE METABOLISM, GLUCOSE METABOLISM, GLYCOPROTEIN, GROWTH FACTOR, HORMONE, MITOGEN, OSTEOGENESIS, SECRETED, IMMUNE SYSTEM
4p9f:A (ALA33) to (LEU44) E. COLI MCBR/YNCC | GNTR FAMILY, TRANSCRIPTIONAL REGULATOR, BIOFILM FORMATION, TRANSCRIPTION
1mt7:A (ASN83) to (GLY94) VIABILITY OF A DRUG-RESISTANT HIV-1 PROTEASE MUTANT: STRUCTURAL INSIGHTS FOR BETTER ANTIVIRAL THERAPY | MATRIX, CAPSID, GAG CLEAVAGE, DRUG RESISTANCE, SUBSTRATE RECOGNITION, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1mt8:A (ASN83) to (GLY94) VIABILITY OF A DRUG-RESISTANT HIV-1 PROTEASE MUTANT: STRUCTURAL INSIGHTS FOR BETTER ANTIVIRAL THERAPY | MATRIX, CAPSID, GAG CLEAVAGE, DRUG RESISTANCE, SUBSTRATE RECOGNITION, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1mt9:A (ASN83) to (GLY94) VIABILITY OF A DRUG-RESISTANT HIV-1 PROTEASE MUTANT: STRUCTURAL INSIGHTS FOR BETTER ANTIVIRAL THERAPY | MATRIX, CAPSID, GAG CLEAVAGE, DRUG RESISTANCE, SUBSTRATE RECOGNITION, HYDROLASE
1mt9:B (ASN83) to (GLY94) VIABILITY OF A DRUG-RESISTANT HIV-1 PROTEASE MUTANT: STRUCTURAL INSIGHTS FOR BETTER ANTIVIRAL THERAPY | MATRIX, CAPSID, GAG CLEAVAGE, DRUG RESISTANCE, SUBSTRATE RECOGNITION, HYDROLASE
1mtr:A (ASN83) to (GLY94) HIV-1 PROTEASE COMPLEXED WITH A CYCLIC PHE-ILE-VAL PEPTIDOMIMETIC INHIBITOR | ASPARTYL PROTEINASE, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1mui:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH LOPINAVIR. | HYDROLASE
5d8w:A (GLN23) to (CYS36) STRUCTRUE OF A LUCIDUM PROTEIN | GH5 FAMILY, GANODERMA LUCIDUM, ENDOGLUCANASE, HYDROLASE
5d8z:A (GLN23) to (CYS36) STRUCTRUE OF A LUCIDUM PROTEIN | GH5 FAMILY, GANODERMA LUCIDUM, ENDOGLUCANASE, HYDROLASE
1mw3:A (ASN186) to (GLY201) AMYLOSUCRASE SOAKED WITH 1M SUCROSE | (BETA-ALPHA)8 BARREL, PROTEIN-SUGAR COMPLEX, TRANSFERASE
1ygs:A (VAL437) to (ALA456) CRYSTAL STRUCTURE OF THE SMAD4 TUMOR SUPPRESSOR C-TERMINAL DOMAIN | SMAD4, TUMOR SUPPRESSOR C-TERMINAL DOMAIN, TGF-BETA SIGNAL MEDIATOR, BETA-SANDWICH SCAFFOLD WITH A THREE-HELIX BUNDLE, TUMOUR SUPPRESSOR
3kt5:A (ASN1083) to (GLY1094) CRYSTAL STRUCTURE OF N88S MUTANT HIV-1 PROTEASE | DRUG RESISTANT, MUTATION, HIV-1 PROTEASE, N88S, NELFINAVIR, HYDROLASE, PROTEASE
1yhs:A (PRO125) to (ARG136) CRYSTAL STRUCTURE OF PIM-1 BOUND TO STAUROSPORINE | PROTEIN KINASE, PROTO-ONCOGENE, TRANSFERASE
1yi3:A (PRO125) to (ARG136) CRYSTAL STRUCTURE OF PIM-1 BOUND TO LY294002 | PROTEIN KINASE, PI3K, TRANSFERASE
3a9r:A (ILE300) to (PHE314) X-RAY STRUCTURES OF BACILLUS PALLIDUS D-ARABINOSE ISOMERASECOMPLEX WITH (4R)-2-METHYLPENTANE-2,4-DIOL | ROSSMANN FOLD, BETA BARREL, CARBOHYDRATE METABOLISM, CYTOPLASM, FUCOSE METABOLISM, ISOMERASE, MANGANESE, METAL- BINDING
3a9r:C (ILE300) to (PHE314) X-RAY STRUCTURES OF BACILLUS PALLIDUS D-ARABINOSE ISOMERASECOMPLEX WITH (4R)-2-METHYLPENTANE-2,4-DIOL | ROSSMANN FOLD, BETA BARREL, CARBOHYDRATE METABOLISM, CYTOPLASM, FUCOSE METABOLISM, ISOMERASE, MANGANESE, METAL- BINDING
3a9s:C (ILE300) to (PHE314) X-RAY STRUCTURE OF BACILLUS PALLIDUS D-ARABINOSE ISOMERASE COMPLEX WITH GLYCEROL | ROSSMANN FOLD, BETA BARREL, CARBOHYDRATE METABOLISM, CYTOPLASM, FUCOSE METABOLISM, ISOMERASE, MANGANESE, METAL- BINDING
3aam:A (PRO163) to (GLY177) CRYSTAL STRUCTURE OF ENDONUCLEASE IV FROM THERMUS THERMOPHILUS HB8 | DNA REPAIR, BASE EXCISION REPAIR, BER, TIM BARREL, ENDONUCLEASE, HYDROLASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
5dcb:A (SER160) to (GLN172) NEISSERIA MENINGITIDIS 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE REGULATED AND COMPLEXED WITH PEP | DAH7PS, REGULATED, ALLOSTERY, TRANSFERASE
5dcb:C (SER160) to (GLN172) NEISSERIA MENINGITIDIS 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE REGULATED AND COMPLEXED WITH PEP | DAH7PS, REGULATED, ALLOSTERY, TRANSFERASE
1n2d:A (GLY135) to (LEU147) TERNARY COMPLEX OF MLC1P BOUND TO IQ2 AND IQ3 OF MYO2P, A CLASS V MYOSIN | PROTEIN-PEPTIDE COMPLEX, IQ MOTIF, MYOSIN LIGHT CHAIN, CELL CYCLE
3kzc:A (LEU3) to (LYS31) CRYSTAL STRUCTURE OF N-ACETYL-L-ORNITHINE TRANSCARBAMYLASE | TRANSCARBAMYLASE, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, CYTOPLASM, TRANSFERASE
1ynu:A (ALA46) to (ASN62) CRYSTAL STRUCTURE OF APPLE ACC SYNTHASE IN COMPLEX WITH L-VINYLGLYCINE | LYASE
4pgf:A (VAL175) to (ASP208) THE STRUCTURE OF MONO-ACETYLATED SAHH | HYDROLYASE ACETYLATION SAHH SEMI-SYNTHETIC, HYDROLASE
3l06:A (PRO139) to (GLY164) CRYSTAL STRUCTURE OF N-ACETYL-L-ORNITHINE TRANSCARBAMYLASE E92V MUTANT COMPLEXED WITH CARBAMYL PHOSPHATE AND N- SUCCINYL-L-NORVALINE | TRANSCARBAMYLASE, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, CYTOPLASM, TRANSFERASE
4pgl:C (GLY60) to (ASP74) CRYSTAL STRUCTURE OF ENGINEERED D-TAGATOSE 3-EPIMERASE PCDTE-ILS6 | EPIMERASE, TIM-BARREL, ISOMERASE
3l0g:A (GLY159) to (CYS170) CRYSTAL STRUCTURE OF NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE FROM EHRLICHIA CHAFFEENSIS AT 2.05A RESOLUTION | SSGCID, NIH, NIAID, SBRI, UW, EMERALD BIOSTRUCTURES, ALS COLLABORATIVE CRYSTALLOGRAPHY, EHRLICHIA CHAFFEENSIS, NICOTINATE- NUCLEOTIDE PYROPHOSPHORYLASE, GLYCOSYLTRANSFERASE, TRANSFERASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3l0g:B (GLY159) to (CYS170) CRYSTAL STRUCTURE OF NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE FROM EHRLICHIA CHAFFEENSIS AT 2.05A RESOLUTION | SSGCID, NIH, NIAID, SBRI, UW, EMERALD BIOSTRUCTURES, ALS COLLABORATIVE CRYSTALLOGRAPHY, EHRLICHIA CHAFFEENSIS, NICOTINATE- NUCLEOTIDE PYROPHOSPHORYLASE, GLYCOSYLTRANSFERASE, TRANSFERASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3l0g:C (GLY159) to (CYS170) CRYSTAL STRUCTURE OF NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE FROM EHRLICHIA CHAFFEENSIS AT 2.05A RESOLUTION | SSGCID, NIH, NIAID, SBRI, UW, EMERALD BIOSTRUCTURES, ALS COLLABORATIVE CRYSTALLOGRAPHY, EHRLICHIA CHAFFEENSIS, NICOTINATE- NUCLEOTIDE PYROPHOSPHORYLASE, GLYCOSYLTRANSFERASE, TRANSFERASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3l0g:D (GLY159) to (CYS170) CRYSTAL STRUCTURE OF NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE FROM EHRLICHIA CHAFFEENSIS AT 2.05A RESOLUTION | SSGCID, NIH, NIAID, SBRI, UW, EMERALD BIOSTRUCTURES, ALS COLLABORATIVE CRYSTALLOGRAPHY, EHRLICHIA CHAFFEENSIS, NICOTINATE- NUCLEOTIDE PYROPHOSPHORYLASE, GLYCOSYLTRANSFERASE, TRANSFERASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
1n49:B (ASN83) to (GLY94) VIABILITY OF A DRUG-RESISTANT HIV-1 PROTEASE VARIANT: STRUCTURAL INSIGHTS FOR BETTER ANTI-VIRAL THERAPY | HIV-1 PROTEASE, DRUG RESISTANCE, SUBSTRATE RECOGNITION, INHIBITOR BINDING, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4phv:B (ASN83) to (GLY94) X-RAY CRYSTAL STRUCTURE OF THE HIV PROTEASE COMPLEX WITH L- 700,417, AN INHIBITOR WITH PSEUDO C2 SYMMETRY | HYDROLASE(ASPARTIC PROTEINASE)
3adk:A (GLY89) to (VAL99) REFINED STRUCTURE OF PORCINE CYTOSOLIC ADENYLATE KINASE AT 2.1 ANGSTROMS RESOLUTION | TRANSFERASE(PHOSPHOTRANSFERASE)
5dgu:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE INHIBITORS CONTAINING SUBSTITUTED FUSED-TETRAHYDROPYRANYL TETRAHYDROFURAN AS P2-LIGAND GRL-004-11A | HIV-1 PROTEASE, ENZYME, HYDROLASE, HYDROLASE INHIBITOR
5dgw:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE INHIBITOR GRL-105-11A CONTAINING SUBSTITUTED FUSED-TETRAHYDROPYRANYL TETRAHYDROFURAN AS P2-LIGAND | HIV-1 PROTEASE, ENZYME, HYDROLASE, HYDROLASE INHIBITOR
5dgz:A (PRO125) to (ARG136) DISCOVERY OF 3,5-SUBSTITUTED 6-AZAINDAZOLES AS POTENT PAN-PIM INHIBITORS | PIM-1, KINASE, ATP-COMPETITIVE, STRUCTURE-BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1yrs:B (ILE19) to (SER36) CRYSTAL STRUCTURE OF KSP IN COMPLEX WITH INHIBITOR 1 | CELL CYCLE
5di8:A (GLN342) to (ASN361) FC KNOB-HOLE HETERODIMER T366W + T366S/L368A/Y407V | HETERODIMER, IMMUNOGLOBULIN, CH3, FC, BISPECIFIC ANTIBODY, IMMUNE SYSTEM
5di8:B (GLN342) to (ASN361) FC KNOB-HOLE HETERODIMER T366W + T366S/L368A/Y407V | HETERODIMER, IMMUNOGLOBULIN, CH3, FC, BISPECIFIC ANTIBODY, IMMUNE SYSTEM
1yt1:A (LYS75) to (SER92) CRYSTAL STRUCTURE OF THE UNLIGANDED FORM OF GRP94, THE ER HSP90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE, GRP94N(DELTA)41 APO CRYSTAL | GRP94, GP96, HSP90, BERGERAT, CHAPERONE, ENDOPLASMIC RETICULUM, HTPG
5dj2:B (GLN342) to (ASN361) FC HETERODIMER DESIGN 7.4 Y407A + T366V/K409V | HETERODIMER, IMMUNOGLOBULIN, CH3, FC, BISPECIFIC ANTIBODY, IMMUNE SYSTEM
5dj6:B (GLN342) to (ASN361) FC HETERODIMER DESIGN 6.1 F405W/Y407A + T366M | HETERODIMER, IMMUNOGLOBULIN, CH3, FC, BISPECIFIC ANTIBODY, IMMUNE SYSTEM
5dja:B (GLN342) to (ASN361) FC HETERODIMER DESIGN 9.1 Y407M + T366I | HETERODIMER, IMMUNOGLOBULIN, CH3, FC, BISPECIFIC ANTIBODY, IMMUNE SYSTEM
5djd:A (GLN342) to (ASN361) FC HETERODIMER DESIGN 5.1 T366V + Y407F | HETERODIMER, IMMUNOGLOBULIN, CH3, FC, BISPECIFIC ANTIBODY, IMMUNE SYSTEM
5djx:A (GLN342) to (ASN361) FC HETERODIMER DESIGN 2.9 L368M/K370E + E357A/S364G | HETERODIMER, IMMUNOGLOBULIN, CH3, FC, BISPECIFIC ANTIBODY, IMMUNE SYSTEM
5djx:B (GLN342) to (ASN361) FC HETERODIMER DESIGN 2.9 L368M/K370E + E357A/S364G | HETERODIMER, IMMUNOGLOBULIN, CH3, FC, BISPECIFIC ANTIBODY, IMMUNE SYSTEM
5djx:E (GLN342) to (ASN361) FC HETERODIMER DESIGN 2.9 L368M/K370E + E357A/S364G | HETERODIMER, IMMUNOGLOBULIN, CH3, FC, BISPECIFIC ANTIBODY, IMMUNE SYSTEM
3l6i:A (GLN16) to (HIS31) CRYSTAL STRUCTURE OF THE UNCHARACTERIZED LIPOPROTEIN YCEB FROM E. COLI AT THE RESOLUTION 2.0A. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER542 | NESG, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, CELL MEMBRANE, LIPOPROTEIN, MEMBRANE, PALMITATE, STRUCTURE GENOMICS, UNKNOWN FUNCTION
1yxu:B (PRO125) to (ARG136) CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH AMP | SER/THR PROTEIN KINASE, TRANSFERASE
1yxu:C (PRO125) to (ARG136) CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH AMP | SER/THR PROTEIN KINASE, TRANSFERASE
1n6e:G (VAL1031) to (GLY1043) TRICORN PROTEASE IN COMPLEX WITH A TRIDECAPEPTIDE CHLOROMETHYL KETONE DERIVATIVE | TRICORN PROTEASE, HYDROLASE, PROPELLER
1n6e:I (VAL1031) to (GLY1043) TRICORN PROTEASE IN COMPLEX WITH A TRIDECAPEPTIDE CHLOROMETHYL KETONE DERIVATIVE | TRICORN PROTEASE, HYDROLASE, PROPELLER
1z0g:E (GLY504) to (ILE522) CRYSTAL STRUCTURE OF A. FULGIDUS LON PROTEOLYTIC DOMAIN | 'ATP-DEPENDENT PROTEASE, CATALYTIC SER-LYS DYAD, B-TYPE LON', HYDROLASE
1z1h:A (ASN83) to (GLY94) HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 3 | MACROCYCLIC INHIBITORS, PEPTIDOMIMETIC INHIBITORS, HIV1 PROTEASE, HYDROLASE
1z1r:A (ASN83) to (GLY94) HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 2 | MACROCYCLIC INHIBITORS, PEPTIDOMIMETIC INHIBITORS, HIV1 PROTEASE, HYDROLASE
3l8c:A (SER114) to (GLU128) STRUCTURE OF PROBABLE D-ALANINE--POLY(PHOSPHORIBITOL) LIGASE SUBUNIT-1 FROM STREPTOCOCCUS PYOGENES | STRUCTURAL GENOMICS, D-ALANINE-POLY(PHOSPHORIBITOL) LIGASE, DLTA, ATP-BINDING, CYTOPLASM, LIGASE, NUCLEOTIDE-BINDING, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
3l8c:B (SER114) to (LEU126) STRUCTURE OF PROBABLE D-ALANINE--POLY(PHOSPHORIBITOL) LIGASE SUBUNIT-1 FROM STREPTOCOCCUS PYOGENES | STRUCTURAL GENOMICS, D-ALANINE-POLY(PHOSPHORIBITOL) LIGASE, DLTA, ATP-BINDING, CYTOPLASM, LIGASE, NUCLEOTIDE-BINDING, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
3l9h:B (ILE19) to (SER36) X-RAY STRUCTURE OF MITOTIC KINESIN-5 (KSP, KIF11, EG5)IN COMPLEX WITH THE HEXAHYDRO-2H-PYRANO[3,2-C]QUINOLINE EMD 534085 | MITOTIC SPINDLE KINESIN, EG5, SMALL MOLECULE INHIBITOR, EMD 534085, ACETYLATION, ATP-BINDING, CELL CYCLE, CELL DIVISION, COILED COIL, MICROTUBULE, MITOSIS, MOTOR PROTEIN, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, POLYMORPHISM
3aid:A (ASN83) to (GLY94) A NEW CLASS OF HIV-1 PROTEASE INHIBITOR: THE CRYSTALLOGRAPHIC STRUCTURE, INHIBITION AND CHEMICAL SYNTHESIS OF AN AMINIMIDE PEPTIDE ISOSTERE | ASPARTYL PROTEASE, PROTEASE, HIV, PEPTIDE ISOSTERE INHIBITOR, DRUG DESIGN
3aig:A (ASN2) to (ASN23) ADAMALYSIN II WITH PEPTIDOMIMETIC INHIBITOR POL656 | SNAKE VENOM METALLOENDOPETIDASE, ZINC PROTEASE, METALLOPROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3aiv:A (LYS483) to (SER498) CRYSTAL STRUCTURE OF BETA-GLUCOSIDASE IN RYE COMPLEXED WITH AN AGLYCONE DIMBOA | TIM BARREL, HYDROLASE
4amc:A (GLY1260) to (GLN1275) CRYSTAL STRUCTURE OF LACTOBACILLUS REUTERI 121 N-TERMINALLY TRUNCATED GLUCANSUCRASE GTFA | TRANSFERASE, GLYCOSYLTRANSFERASE, REUTERANSUCRASE
4ps9:A (VAL51) to (PHE70) APO STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS | ALDEHYDE DEHYDROGENASE, APO STRUCTURE, ROSSMANN FOLD, OXIDOREDUCTASE
4ps9:C (VAL51) to (PHE70) APO STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS | ALDEHYDE DEHYDROGENASE, APO STRUCTURE, ROSSMANN FOLD, OXIDOREDUCTASE
4ps9:D (VAL51) to (GLU71) APO STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS | ALDEHYDE DEHYDROGENASE, APO STRUCTURE, ROSSMANN FOLD, OXIDOREDUCTASE
4pt3:C (VAL51) to (PHE70) NADPH COMPLEX STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS | ALDEHYDE DEHYDROGENASE, NAPDH-COMPLEX STRUCTURE, NADPH, ROSSMANN FOLD, OXIDOREDUCTASE
3al0:B (PRO284) to (LEU299) CRYSTAL STRUCTURE OF THE GLUTAMINE TRANSAMIDOSOME FROM THERMOTOGA MARITIMA IN THE GLUTAMYLATION STATE. | PROTEIN-RNA COMPLEX, LIGASE-RNA COMPLEX
5dr6:A (ALA160) to (GLY173) AURORA A KINASE IN COMPLEX WITH AA30 AND JNJ-7706621 IN SPACE GROUP P6122 | AURORA A KINASE, MITOTIC KINASE, PPI, TRANSFERASE
5dt5:B (HIS117) to (GLY128) CRYSTAL STRUCTURE OF THE GH1 BETA-GLUCOSIDASE FROM EXIGUOBACTERIUM ANTARCTICUM B7 IN SPACE GROUP P21 | GH1 FAMILY, BETA-GLUCOSIDASE, COLD-ACTIVE, TETRAMER, HYDROLASE
5dt5:C (HIS117) to (GLY128) CRYSTAL STRUCTURE OF THE GH1 BETA-GLUCOSIDASE FROM EXIGUOBACTERIUM ANTARCTICUM B7 IN SPACE GROUP P21 | GH1 FAMILY, BETA-GLUCOSIDASE, COLD-ACTIVE, TETRAMER, HYDROLASE
5dt5:D (HIS117) to (GLY128) CRYSTAL STRUCTURE OF THE GH1 BETA-GLUCOSIDASE FROM EXIGUOBACTERIUM ANTARCTICUM B7 IN SPACE GROUP P21 | GH1 FAMILY, BETA-GLUCOSIDASE, COLD-ACTIVE, TETRAMER, HYDROLASE
5dt5:E (HIS117) to (GLY128) CRYSTAL STRUCTURE OF THE GH1 BETA-GLUCOSIDASE FROM EXIGUOBACTERIUM ANTARCTICUM B7 IN SPACE GROUP P21 | GH1 FAMILY, BETA-GLUCOSIDASE, COLD-ACTIVE, TETRAMER, HYDROLASE
1zeo:B (GLN345) to (LEU356) CRYSTAL STRUCTURE OF HUMAN PPAR-GAMMA LIGAND BINDING DOMAIN COMPLEXED WITH AN ALPHA-ARYLOXYPHENYLACETIC ACID AGONIST | NUCLEAR RECEPTOR, LIGAND BINDING DOMAIN, LBD, ALPHA HELIX SANDWICH, PPAR-RXR HETERODIMER, TRANSCRIPTION
5dvl:A (GLY341) to (ASN361) FC DESIGN 20.8.37 A CHAIN HOMODIMER Y349S/T366M/K370Y/K409V | HEAD-TO-TAIL HOMODIMER, IMMUNOGLOBULIN, FC, IMMUNE SYSTEM
4pzp:A (VAL115) to (THR129) SUBSTRATE-FREE STRUCTURE OF D-ALANINE CARRIER PROTEIN LIGASE DLTA FROM BACILLUS CEREUS | HOMOLOGOUS TO ACETYL-COA SYNTHETASE, LIGASE
4arc:A (GLU124) to (GLY147) TERNARY COMPLEX OF E. COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND LEUCINE IN THE EDITING CONFORMATION | LIGASE-RNA COMPLEX, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, CLASS I AMINOACYL-TRNA SYNTHETASE, ATP-BINDING, METAL-BINDING
3lnt:A (SER0) to (ASN18) CRYSTAL STRUCTURE OF PHOSPHOGLYCEROMUTASE FROM BURKHOLDERIA PSEUDOMALLEI 1710B WITH BOUND MALONIC ACID | MUTASE, PHOSPHOGLYCERYLMUTASE, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, GLYCOLYSIS, ISOMERASE
4q1s:T (HIS224) to (ASN244) YEAST 20S PROTEASOME IN COMPLEX WITH KENDOMYCIN | PROTEASOME, NATURAL PRODUCT, QUINONE METHIDE, COVALENT BINDING, EXOSITE, HYDROLASE-TOXIN COMPLEX
1zm2:C (GLY217) to (GLY234) STRUCTURE OF ADP-RIBOSYLATED EEF2 IN COMPLEX WITH CATALYTIC FRAGMENT OF ETA | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
1zm3:C (GLY217) to (GLY234) STRUCTURE OF THE APO EEF2-ETA COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
5dyv:C (GLY91) to (SER101) ABYU - WILDTYPE | ABYU, DIELS-ALDERASE, DIELS-ALDER, CYCLASE, [4+2] CYCLOADDITION, TETRONATE, SPIROTETRONATE, POLYKETIDE, ABYSSOMICIN, LIGASE
1zp3:C (ASN278) to (GLY291) E. COLI METHYLENETETRAHYDROFOLATE REDUCTASE (OXIDIZED) | TIM BARREL, FLAVIN, REDUCTASE, OXIDOREDUCTASE
3lre:B (LYS13) to (GLY29) CRYSTAL STRUCTURE ANALYSIS OF HUMAN KINESIN-8 MOTOR DOMAIN | MOTOR PROTEIN, NUCLEOTIDE BINDING, MICROTUBULE BINDING, ATP-BINDING, CELL PROJECTION, CYTOSKELETON, GLYCOPROTEIN, MICROTUBULE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTEIN TRANSPORT, TRANSPORT
1zrq:C (ASN278) to (GLY291) ESCHERICHIA COLI METHYLENETETRAHYDROFOLATE REDUCTASE (REDUCED) COMPLEXED WITH NADH, PH 6.0 | TIM BARREL, FLAVIN, REDUCTASE, NADH, OXIDOREDUCTASE
1zs2:A (ASN186) to (GLY201) AMYLOSUCRASE MUTANT E328Q IN A TERNARY COMPLEX WITH SUCROSE AND MALTOHEPTAOSE | TERNARY COMPLEX, (BETA/ALPHA)8-BARREL,, TRANSFERASE
4q5j:A (PRO867) to (THR880) CRYSTAL STRUCTURE OF SEMET DERIVATIVE BRI1 IN COMPLEX WITH BKI1 | KINASE DOMAIN, ATP BINDING, PHOSPHORYLATION, SEMET LABELLED, MEMBRANE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1zsr:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE (BRU ISOLATE) WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR BOC-PHE-PSI[S-CH(OH) CH2NH]-PHE-GLU-PHE-NH2 | HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1zsx:A (CYS37) to (THR51) CRYSTAL STRUCTURE OF HUMAN POTASSIUM CHANNEL KV BETA-SUBUNIT (KCNAB2) | POTASSIUM CHANNEL, KV BETA-SUBUNIT, HUMAN, ALDO-KETO REDUCTASE, STRUCTURAL GENOMICS, SGC, STRUCTURAL GENOMICS CONSORTIUM, OXIDOREDUCTASE
3apr:E (ASP120) to (SER145) BINDING OF A REDUCED PEPTIDE INHIBITOR TO THE ASPARTIC PROTEINASE FROM RHIZOPUS CHINENSIS. IMPLICATIONS FOR A MECHANISM OF ACTION | HYDROLASE, ASPARTIC PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1ztz:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV PROTEASE- METALLACARBORANE COMPLEX | RATIONAL DRUG DESIGN; HIV PROTEASE INHIBITORS; ASPARTIC PROTEASES; CARBORANES; METALLACARBORANES, HYDROLASE
1zud:4 (MET1) to (ASP26) STRUCTURE OF THIS-THIF PROTEIN COMPLEX | THIAMIN, THIAZOLE, PROTEIN-PROTEIN COMPLEX, THIS, THIF, TRANSFERASE- BIOSYNTHETIC PROTEIN COMPLEX
1zvk:A (GLY344) to (LEU356) STRUCTURE OF DOUBLE MUTANT, D164N, E78H OF KUMAMOLISIN-AS | D164N,E78H, HYDROLASE
4avo:A (ALA148) to (PRO164) THERMOBIFIDA FUSCA CELLOBIOHYDROLASE CEL6B CATALYTIC MUTANT D274A COCRYSTALLIZED WITH CELLOBIOSE | HYDROLASE, CELLULOSE DEGRADATION, GLYCOSIDE HYDROLASE FAMILY 6, CELLULASE
3lvb:A (LYS247) to (GLU256) CRYSTAL STRUCTURE OF THE FERREDOXIN:NADP+ REDUCTASE FROM MAIZE ROOT AT 1.7 ANGSTROMS - TEST SET WITHHELD | ELECTRON TRANSPORT, OXIDOREDUCTASE
4ayg:A (GLY1259) to (GLU1274) LACTOBACILLUS REUTERI N-TERMINALLY TRUNCATED GLUCANSUCRASE GTF180 IN ORTHORHOMBIC APO-FORM | TRANSFERASE, GLYCOSYLTRANSFERASE, GLYCOSYL HYDROLASE FAMILY 70, CIRCULARLY PERMUTED BETA-ALPHA BARREL
3aup:B (TYR60) to (ASN74) CRYSTAL STRUCTURE OF BASIC 7S GLOBULIN FROM SOYBEAN | PEPSIN-LIKE FOLD, PLANT PROTEIN
3aup:C (TYR60) to (ASN74) CRYSTAL STRUCTURE OF BASIC 7S GLOBULIN FROM SOYBEAN | PEPSIN-LIKE FOLD, PLANT PROTEIN
3lxm:B (VAL123) to (GLY151) 2.00 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A CATALYTIC SUBUNIT OF AN ASPARTATE CARBAMOYLTRANSFERASE (PYRB) FROM YERSINIA PESTIS CO92 | ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC SUBUNIT, YERSINIA PESTIS CO92, INFECTIOUS DISEASES, STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
3lzs:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 CRF01_AE PROTEASE IN COMPLEX WITH DARUNAVIR | HIV-1 PROTEASE, NON-B CLADES, CRF01_AE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, HYDROLASE
4qbj:A (TYR395) to (ASN405) CRYSTAL STRUCTURE OF N-MYRISTOYL TRANSFERASE FROM ASPERGILLUS FUMIGATUS COMLEXED WITH A SYNTHETIC INHIBITOR | TRANSFERASE, MYRISTOYL-COA, MYRISTATE TRANSLOCATION, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3ay4:B (GLN342) to (ASN361) CRYSTAL STRUCTURE OF NONFUCOSYLATED FC COMPLEXED WITH BIS-GLYCOSYLATED SOLUBLE FORM OF FC GAMMA RECEPTOR IIIA | IMMUNE SYSTEM, COMPLEX, FC FRAGMENT, IGG, RECEPTOR, CD16, GAMMA
4qet:A (VAL51) to (GLU71) STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS, G224D MUTANT | ROSSMANN FOLD, ALDEHYDE DEHYDROGENASE, OXIDOREDUCTASE
4qet:D (VAL51) to (PHE70) STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS, G224D MUTANT | ROSSMANN FOLD, ALDEHYDE DEHYDROGENASE, OXIDOREDUCTASE
4qf6:A (VAL51) to (PHE70) STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS, E194S MUTANT | ROSSMANN, ALDEHYDE DEHYDROGENASE, OXIDOREDUCTASE, E194S
4qf6:C (VAL51) to (PHE70) STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS, E194S MUTANT | ROSSMANN, ALDEHYDE DEHYDROGENASE, OXIDOREDUCTASE, E194S
4qf6:D (VAL51) to (PHE70) STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS, E194S MUTANT | ROSSMANN, ALDEHYDE DEHYDROGENASE, OXIDOREDUCTASE, E194S
4qf6:E (VAL51) to (PHE70) STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS, E194S MUTANT | ROSSMANN, ALDEHYDE DEHYDROGENASE, OXIDOREDUCTASE, E194S
4qf6:F (VAL51) to (PHE70) STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS, E194S MUTANT | ROSSMANN, ALDEHYDE DEHYDROGENASE, OXIDOREDUCTASE, E194S
4qf6:G (VAL51) to (ALA69) STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS, E194S MUTANT | ROSSMANN, ALDEHYDE DEHYDROGENASE, OXIDOREDUCTASE, E194S
4qf6:H (VAL51) to (PHE70) STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS, E194S MUTANT | ROSSMANN, ALDEHYDE DEHYDROGENASE, OXIDOREDUCTASE, E194S
4qf6:L (VAL51) to (PHE70) STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS, E194S MUTANT | ROSSMANN, ALDEHYDE DEHYDROGENASE, OXIDOREDUCTASE, E194S
3m4o:E (SER59) to (PHE72) RNA POLYMERASE II ELONGATION COMPLEX B | TRANSCRIPTION, MRNA, MULTIPROTEIN COMPLEX, MOLECULAR MACHINE, DNA, DNA DAMAGE, CANCER, PLATINUM DRUG, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, METAL-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
3azt:D (MET1) to (GLY13) DIVERSE SUBSTRATES RECOGNITION MECHANISM REVEALED BY THERMOTOGA MARITIMA CEL5A STRUCTURES IN COMPLEX WITH CELLOTETRAOSE | CELLULOSE, CELLULASE, BIOFUEL, TIM BARREL, HYDROLASE
3b20:B (ALA148) to (LEU160) CRYSTAL STRUCTURE OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE COMPLEXED WITH NADFROM SYNECHOCOCCUS ELONGATUS" | ALPHA/BETA FOLD, OXIDOREDUCTASE
3b20:O (ALA148) to (LEU160) CRYSTAL STRUCTURE OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE COMPLEXED WITH NADFROM SYNECHOCOCCUS ELONGATUS" | ALPHA/BETA FOLD, OXIDOREDUCTASE
4qgi:B (ASN83) to (GLY94) X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE VARIANT G48T/L89M IN COMPLEX WITH SAQUINAVIR | SAQUINAVIR, HIV PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2a79:A (CYS51) to (THR65) MAMMALIAN SHAKER KV1.2 POTASSIUM CHANNEL- BETA SUBUNIT COMPLEX | POTASSIUM CHANNEL, VOLTAGE SENSOR, VOLTAGE DEPENDENT, ION CHANNEL, SHAKER, MEMBRANE PROTEIN, EUKARYOTIC, KV1.2
4qhr:B (THR318) to (GLY337) THE STRUCTURE OF ALANINE RACEMASE FROM ACINETOBACTER BAUMANNII | ALPHA/BETA BARREL, RACEMIZATION, ISOMERASE
4qhs:D (VAL294) to (LYS306) CRYSTAL STRUCTURE OF AAA+SIGMA 54 ACTIVATOR DOMAIN OF THE FLAGELLAR REGULATORY PROTEIN FLRC OF VIBRIO CHOLERAE IN NUCLEOTIDE FREE STATE | AAA+ ATPASE DOMAIN, ATPASE ACTIVITY, TRANSCRIPTION
3m9f:B (ASN83) to (GLY94) HIV PROTEASE COMPLEXED WITH COMPOUND 10B | HIV, PROTEASE, TRANSFERASE
2a9j:B (LYS3) to (ASN20) HUMAN BISPHOSPHOGLYCERATE MUTASE COMPLEXED WITH 3- PHOSPHOGLYCERATE (17 DAYS) | BISPHOSPHOGLYCERATE MUTASE, 3-PHOSPHOGLYCERATE, ISOMERASE
3b5q:A (LEU327) to (GLY343) CRYSTAL STRUCTURE OF A PUTATIVE SULFATASE (NP_810509.1) FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 AT 2.40 A RESOLUTION | NP_810509.1, PUTATIVE SULFATASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, HYDROLASE
4qj9:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (R452S) | CO-EVOLUTION, PROTEASE, HYDROLASE
3b6v:A (SER8) to (GLY28) CRYSTAL STRUCTURE OF THE MOTOR DOMAIN OF HUMAN KINESIN FAMILY MEMBER 3C IN COMPLEX WITH ADP | KINESIN, STRUCTURAL GENOMICS CONSORTIUM, MOTOR DOMAIN, ADP, SGC, ATP- BINDING, MICROTUBULE, MOTOR PROTEIN, NUCLEOTIDE-BINDING
2aeg:C (PRO93) to (PHE112) X-RAY CRYSTAL STRUCTURE OF PROTEIN ATU5096 FROM AGROBACTERIUM TUMEFACIENS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ATR63. | ALPHA-BETA PROTEIN., STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
3b78:C (GLY217) to (PHE233) STRUCTURE OF THE EEF2-EXOA(R551H)-NAD+ COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, TOXIN-SUBSTRATE COMPLEX, CYTOPLASM, GTP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PROTEIN BIOSYNTHESIS, RNA-BINDING, RRNA- BINDING, GLYCOSYLTRANSFERASE, NAD, TRANSFERASE, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
3b7k:A (VAL106) to (HIS150) HUMAN ACYL-COENZYME A THIOESTERASE 12 | HOTDOG FOLD, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, FATTY ACID METABOLISM, HYDROLASE, LIPID METABOLISM, SERINE ESTERASE
3b7v:B (ASN183) to (GLY194) HIV-1 PROTEASE COMPLEXED WITH GEM-DIOL-AMINE TETRAHEDRAL INTERMEDIATE NLLTQI | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3b80:A (ASN83) to (GLY94) HIV-1 PROTEASE MUTANT I54V COMPLEXED WITH GEM-DIOL-AMINE INTERMEDIATE NLLTQI | HYDROLASE-HYDROLASE SUBSTRATE COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qlq:F (HIS224) to (ASN244) YCP IN COMPLEX WITH TRIPEPTIDIC EPOXYKETONE INHIBITOR 8 | PROTEASOME, EPOXYKETONE, IMMUNOPROTEASOME INHIBITOR, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qlq:T (HIS224) to (ASN244) YCP IN COMPLEX WITH TRIPEPTIDIC EPOXYKETONE INHIBITOR 8 | PROTEASOME, EPOXYKETONE, IMMUNOPROTEASOME INHIBITOR, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3b82:C (GLY217) to (PHE233) STRUCTURE OF THE EEF2-EXOA(E546H)-NAD+ COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, TOXIN-SUBSTRATE COMPLEX, CYTOPLASM, GTP-BINDING, NUCLEOTIDE-BINDING, PHOSPHORYLATION, PROTEIN BIOSYNTHESIS, RNA-BINDING, RRNA- BINDING, GLYCOSYLTRANSFERASE, NAD, TRANSFERASE, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
4qlt:F (HIS224) to (ASN244) YCP IN COMPLEX WITH TRIPEPTIDIC EPOXYKETONE INHIBITOR 2 (PR924) | PROTEASOME, EPOXYKETONE, IMMUNOPROTEASOME INHIBITOR, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qlt:T (HIS224) to (ASN244) YCP IN COMPLEX WITH TRIPEPTIDIC EPOXYKETONE INHIBITOR 2 (PR924) | PROTEASOME, EPOXYKETONE, IMMUNOPROTEASOME INHIBITOR, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3mek:A (GLY194) to (ASN205) CRYSTAL STRUCTURE OF HUMAN HISTONE-LYSINE N- METHYLTRANSFERASE SMYD3 IN COMPLEX WITH S-ADENOSYL-L- METHIONINE | HISTONE METHYLTRANSFERASE, SET AND MYND DOMAIN-CONTAINING PROTEIN 3, ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 1, HISTONE H3, DI-METHYLATION, TRI-METHYLATION, TRANSCRIPTIONAL ACTIVATION, DNA-BINDING, MYND-TYPE ZINC FINGER, SET DOMAIN, CHROMATIN MODIFICATION, ALTERNATIVE SPLICING, CHROMATIN REGULATOR, CYTOPLASM, METAL-BINDING, METHYLTRANSFERASE, NUCLEUS, S-ADENOSYL-L-METHIONINE, TRANSFERASE, ZINC, ZINC-FINGER, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
3mg7:T (HIS221) to (ASN241) STRUCTURE OF YEAST 20S OPEN-GATE PROTEASOME WITH COMPOUND 8 | 20S PROTEASOME, HYDROLASE
3mh9:C (PRO37) to (LEU55) CRYSTAL STRUCTURE OF LPRG MUTANT V91W FROM MYCOBACTERIUM TUBERCULOSIS | LIPOPROTEIN, MUTANT LPRG, GLYCOLIPID BINDING PROTEIN, LIPID BINDING PROTEIN, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC
3mh9:A (PRO37) to (LEU55) CRYSTAL STRUCTURE OF LPRG MUTANT V91W FROM MYCOBACTERIUM TUBERCULOSIS | LIPOPROTEIN, MUTANT LPRG, GLYCOLIPID BINDING PROTEIN, LIPID BINDING PROTEIN, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC
3mha:B (PRO37) to (LEU55) CRYSTAL STRUCTURE OF LPRG FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO PIM | LIPOPROTEIN, LPRG, GLYCOLIPID BINDING PROTEIN, LIPID BINDING PROTEIN, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC
3mhf:B (VAL20) to (HIS39) TAGATOSE-1,6-BISPHOSPHATE ALDOLASE FROM STREPTOCOCCUS PYOGENES | TAGATOSE ALDOLASE CLASS I, BETA BARREL, STREPTOCOCCUS PYOGENES, LYASE
3mhg:B (VAL20) to (GLN40) DIHYDROXYACETONE PHOSPHATE CARBANION INTERMEDIATE IN TAGATOSE-1,6- BISPHOSPHATE ALDOLASE FROM STREPTOCOCCUS PYOGENES | TAGATOSE ALDOLASE CLASS I, BETA BARREL, STREPTOCOCCUS PYOGENES, SCHIFF BASE, CARBANION, LYASE
3mhg:D (VAL20) to (GLN40) DIHYDROXYACETONE PHOSPHATE CARBANION INTERMEDIATE IN TAGATOSE-1,6- BISPHOSPHATE ALDOLASE FROM STREPTOCOCCUS PYOGENES | TAGATOSE ALDOLASE CLASS I, BETA BARREL, STREPTOCOCCUS PYOGENES, SCHIFF BASE, CARBANION, LYASE
3bbu:A (LEU84) to (THR108) THE HSP15 PROTEIN FITTED INTO THE LOW RESOLUTION CRYO-EM MAP OF THE 50S.NC-TRNA.HSP15 COMPLEX | ALPHA-L RNA BINDING, HEAT SHOCK, RESCUE STALLED RIBOSOME, RIBOSOME
5emn:A (HIS604) to (ASP615) CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 REDUCTASE(A287P MUTANT) | HUMAN CYPOR, ABS-LIKE PHENOTYPE, FLAVOPROTEIN, CYTOCHROME P450 REDUCTASE, OXIDOREDUCTASE
5eol:A (PRO125) to (ARG136) CRYSTAL STRUCTURE OF HUMAN PIM-1 KINASE IN COMPLEX WITH A MACROCYCLIC QUINOXALINE-PYRROLODIHYDROPIPERIDINONE INHIBITOR | TRANSFERASE, SERINE/THREONINE PROTEIN KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3mla:B (GLY81) to (TYR96) BANADD IN COMPLEX WITH INHIBITOR 1_02 | NMNAT-INHIBITOR COMPLEX, TRANSFERASE
3mlb:A (GLY81) to (LYS95) BANADD IN COMPLEX WITH INHIBITOR 1_02_1 | ENZYME-INHIBITOR COMPLEX, TRANSFERASE
4bfr:A (LEU272) to (ALA296) DISCOVERY AND OPTIMIZATION OF PYRIMIDONE INDOLINE AMIDE PI3KBETA INHIBITORS FOR THE TREATMENT OF PHOSPHATASE AND TENSIN HOMOLOGUE (PTEN)-DEFICIENT CANCERS | TRANSFERASE, INHIBITOR
3mpu:A (VAL122) to (THR148) CRYSTAL STRUCTURE OF THE C47A/A241C DISULFIDE-LINKED E. COLI ASPARTATE TRANSCARBAMOYLASE HOLOENZYME | ASPARTATE TRANCARBAMOYLASE, DISULFIDE BOND, PHOSPHATE, CATALYSIS, PRODUCT RELEASE, ORDERED-SEQUENTIAL MECHANISM, TRANSFERASE
3mpu:C (VAL122) to (THR148) CRYSTAL STRUCTURE OF THE C47A/A241C DISULFIDE-LINKED E. COLI ASPARTATE TRANSCARBAMOYLASE HOLOENZYME | ASPARTATE TRANCARBAMOYLASE, DISULFIDE BOND, PHOSPHATE, CATALYSIS, PRODUCT RELEASE, ORDERED-SEQUENTIAL MECHANISM, TRANSFERASE
3mpu:E (VAL122) to (THR148) CRYSTAL STRUCTURE OF THE C47A/A241C DISULFIDE-LINKED E. COLI ASPARTATE TRANSCARBAMOYLASE HOLOENZYME | ASPARTATE TRANCARBAMOYLASE, DISULFIDE BOND, PHOSPHATE, CATALYSIS, PRODUCT RELEASE, ORDERED-SEQUENTIAL MECHANISM, TRANSFERASE
4qtp:C (GLU57) to (LYS73) CRYSTAL STRUCTURE OF AN ANTI-SIGMA FACTOR ANTAGONIST FROM MYCOBACTERIUM PARATUBERCULOSIS | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, STAS DOMAIN, ANTI-SIGMA FACTOR ANTAGONIST, PROTEIN BINDING
4qtp:D (GLU57) to (LYS73) CRYSTAL STRUCTURE OF AN ANTI-SIGMA FACTOR ANTAGONIST FROM MYCOBACTERIUM PARATUBERCULOSIS | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, STAS DOMAIN, ANTI-SIGMA FACTOR ANTAGONIST, PROTEIN BINDING
4qv0:T (HIS224) to (ASN244) YCP BETA5-A49T-A50V-DOUBLE MUTANT | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE
4qv3:F (HIS224) to (ASN244) YCP BETA5-M45V MUTANT | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE
4qv3:T (HIS224) to (ASN244) YCP BETA5-M45V MUTANT | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE
4qvm:F (HIS224) to (ASN244) YCP BETA5-M45A MUTANT IN COMPLEX WITH BORTEZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qvm:T (HIS224) to (ASN244) YCP BETA5-M45A MUTANT IN COMPLEX WITH BORTEZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qvn:F (HIS224) to (ASN244) YCP BETA5-M45V MUTANT IN COMPLEX WITH BORTEZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qvn:T (HIS224) to (ASN244) YCP BETA5-M45V MUTANT IN COMPLEX WITH BORTEZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qw5:F (HIS224) to (ASN244) YCP BETA5-M45A MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qw5:T (HIS224) to (ASN244) YCP BETA5-M45A MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qw4:F (HIS224) to (ASN244) YCP IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qw4:T (HIS224) to (ASN244) YCP IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qw6:F (HIS224) to (ASN244) YCP BETA5-M45V MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qw6:T (HIS224) to (ASN244) YCP BETA5-M45V MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qwf:F (HIS224) to (ASN244) YCP BETA5-M45I MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qwf:T (HIS224) to (ASN244) YCP BETA5-M45I MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5f0a:A (ILE376) to (LEU388) CRYSTAL STRUCTURE OF PVX_084705 WITH BOUND 1-TERT-BUTYL-3-(3- CHLOROPHENOXY)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE INHIBITOR | STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4qwk:F (HIS224) to (ASN244) YCP BETA5-A49T-A50V-DOUBLE MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qwk:T (HIS224) to (ASN244) YCP BETA5-A49T-A50V-DOUBLE MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qwr:F (HIS224) to (ASN244) YCP BETA5-C52F MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qwr:T (HIS224) to (ASN244) YCP BETA5-C52F MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qws:F (HIS224) to (ASN244) YCP BETA5-C63F MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qws:T (HIS224) to (ASN244) YCP BETA5-C63F MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3mw8:A (ALA37) to (ALA50) CRYSTAL STRUCTURE OF AN UROPORPHYRINOGEN-III SYNTHASE (SAMA_3255) FROM SHEWANELLA AMAZONENSIS SB2B AT 1.65 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE, HEMD-LIKE, HEME
3mxd:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE INHIBITOR KC53 IN COMPLEX WITH WILD-TYPE PROTEASE | DRUG DESIGN, HIV-1 PROTEASE, PROTEASE INHIBITORS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qz2:F (HIS224) to (ASN244) YCP BETA5-M45I MUTANT IN COMPLEX WITH THE EPOXYKETONE INHIBITOR ONX 0914 | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qz2:T (HIS224) to (ASN244) YCP BETA5-M45I MUTANT IN COMPLEX WITH THE EPOXYKETONE INHIBITOR ONX 0914 | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qz3:F (HIS224) to (ASN244) YCP BETA5-A49V MUTANT IN COMPLEX WITH THE EPOXYKETONE INHIBITOR ONX 0914 | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qz3:T (HIS224) to (ASN244) YCP BETA5-A49V MUTANT IN COMPLEX WITH THE EPOXYKETONE INHIBITOR ONX 0914 | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qz4:F (HIS224) to (ASN244) YCP BETA5-A49S MUTANT IN COMPLEX WITH THE EPOXYKETONE INHIBITOR ONX 0914 | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qz4:T (HIS224) to (ASN244) YCP BETA5-A49S MUTANT IN COMPLEX WITH THE EPOXYKETONE INHIBITOR ONX 0914 | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3myp:A (GLY19) to (THR41) CRYSTAL STRUCTURE OF TAGATOSE-1,6-BISPHOSPHATE ALDOLASE FROM STAPHYLOCOCCUS AUREUS | BETA-ALPHA-BARREL, LYASE
3myp:C (ILE20) to (LYS38) CRYSTAL STRUCTURE OF TAGATOSE-1,6-BISPHOSPHATE ALDOLASE FROM STAPHYLOCOCCUS AUREUS | BETA-ALPHA-BARREL, LYASE
3myp:D (ILE20) to (GLN40) CRYSTAL STRUCTURE OF TAGATOSE-1,6-BISPHOSPHATE ALDOLASE FROM STAPHYLOCOCCUS AUREUS | BETA-ALPHA-BARREL, LYASE
4qz6:T (HIS224) to (ASN244) YCP BETA5-A49T-A50V DOUBLE MUTANT IN COMPLEX WITH THE EPOXYKETONE INHIBITOR ONX 0914 | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3bva:B (ASN83) to (GLY94) CYSTAL STRUCTURE OF HIV-1 ACTIVE SITE MUTANT D25N AND P2-NC ANALOG INHIBITOR | DRUG RESISTANCE, HIV-1, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3bvb:B (ASN83) to (GLY94) CYSTAL STRUCTURE OF HIV-1 ACTIVE SITE MUTANT D25N AND INHIBITOR DARUNAVIR | DRUG RESISTANCE; HIV-1; D25N, MUTANT, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, DNA INTEGRATION, DNA RECOMBINATION, DNA- DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC-FINGER
3bvh:F (GLU225) to (ILE236) CRYSTAL STRUCTURE OF RECOMBINANT GAMMAD364A FIBRINOGEN FRAGMENT D WITH THE PEPTIDE LIGAND GLY-PRO-ARG-PRO-AMIDE | BLOOD CLOTTING, BLOOD COAGULATION, DISEASE MUTATION, GLYCOPROTEIN, PHOSPHOPROTEIN, SECRETED, PYRROLIDONE CARBOXYLIC ACID, SULFATION
3bvp:A (SER111) to (TYR138) CRYSTAL STRUCTURE OF THE N-TERMINAL CATALYTIC DOMAIN OF TP901-1 INTEGRASE | DNA RECOMBINASE, RECOMBINATION
3bvp:B (SER111) to (LEU136) CRYSTAL STRUCTURE OF THE N-TERMINAL CATALYTIC DOMAIN OF TP901-1 INTEGRASE | DNA RECOMBINASE, RECOMBINATION
4qzw:F (HIS224) to (ASN244) YCP BETA5-C52F MUTANT IN COMPLEX WITH THE EPOXYKETONE INHIBITOR ONX 0914 | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qzw:T (HIS224) to (ASN244) YCP BETA5-C52F MUTANT IN COMPLEX WITH THE EPOXYKETONE INHIBITOR ONX 0914 | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3bwk:A (TYR8) to (TYR19) CRYSTAL STRUCTURE OF FALCIPAIN-3 WITH ITS INHIBITOR, K11017 | FALCIPAIN, MALARIA, CYSTEINE PROTEASE, HYDROLASE
3bwk:C (TYR8) to (TYR19) CRYSTAL STRUCTURE OF FALCIPAIN-3 WITH ITS INHIBITOR, K11017 | FALCIPAIN, MALARIA, CYSTEINE PROTEASE, HYDROLASE
3bxr:A (ASN83) to (GLY94) CRYSTAL STRUCTURES OF HIGHLY CONSTRAINED SUBSTRATE AND HYDROLYSIS PRODUCTS BOUND TO HIV-1 PROTEASE. IMPLICATIONS FOR CATALYTIC MECHANISM | HIV PROTEASE, HIVPR, SUBSTRATE, PRODUCT, MECHANISM, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER
5fa6:B (HIS604) to (ASP615) WILD TYPE HUMAN CYPOR | CYPOR, CYTOCHROME P450 REDUCTASE, FLAVOPROTEIN, ABS-LIKE PHENOTYPE, OXIDOREDUCTASE
3c38:A (ASP113) to (ALA148) CRYSTAL STRUCTURE OF THE PERIPLASMIC DOMAIN OF VIBRIO CHOLERAE LUXQ | 2-COMPONENT SYSTEM, QUORUM SENSING, HISTIDINE KINASE, HYDROLASE, INNER MEMBRANE, MEMBRANE, PHOSPHOPROTEIN, PROTEIN PHOSPHATASE, TRANSFERASE, TRANSMEMBRANE, TWO- COMPONENT REGULATORY SYSTEM, SIGNALING PROTEIN
5fgd:F (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA5-H(-2)L-T1A DOUBLE MUTANT IN COMPLEX WITH CARFILZOMIB | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
5fgd:T (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA5-H(-2)L-T1A DOUBLE MUTANT IN COMPLEX WITH CARFILZOMIB | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
4r5q:A (ARG51) to (GLU62) CRYSTAL STRUCTURE AND NUCLEASE ACTIVITY OF THE CRISPR-ASSOCIATED CAS4 PROTEIN PCAL_0546 FROM PYROBACULUM CALIDIFONTIS CONTAINING A [2FE-2S] CLUSTER | MCSG, STRUCTURAL GENOMICS, PSI-BIOLOGY, EXONUCLEASE, HYDROLASE, MIDWEST CENTER FOR STRUCTURAL GENOMICS
3c4e:C (PRO125) to (ARG136) PIM-1 KINASE DOMAIN IN COMPLEX WITH 3-AMINOPHENYL-7- AZAINDOLE | PIM-1, PROTO-ONCOGENE, SERINE/THREONINE KINASE, ALTERNATIVE INITIATION, ATP-BINDING, CYTOPLASM, MANGANESE, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
5fh3:A (MET173) to (GLY185) THE STRUCTURE OF RAT CYTOSOLIC PEPCK VARIANT E89A IN COMPLEX WITH OXALIC ACID AND GTP | KINASE, GLUCONEOGENESIS, LYASE
3c6f:B (LEU220) to (SER230) CRYSTAL STRUCTURE OF PROTEIN BSU07140 FROM BACILLUS SUBTILIS | UNCHARACTERIZED PROTEIN, PREDICTED MEMBRANE PROTEIN, PROTEIN STRUCTURE INITIATIVE, PSI-2, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
3c6f:D (LEU220) to (THR231) CRYSTAL STRUCTURE OF PROTEIN BSU07140 FROM BACILLUS SUBTILIS | UNCHARACTERIZED PROTEIN, PREDICTED MEMBRANE PROTEIN, PROTEIN STRUCTURE INITIATIVE, PSI-2, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, STRUCTURAL GENOMICS, UNKNOWN FUNCTION
4by4:B (GLY41) to (PHE56) CRYSTAL STRUCTURE OF DROSOPHILA FRQ2 | CALCIUM-BINDING PROTEIN
3c8w:A (ARG160) to (LYS172) CRYSTAL STRUCTURE OF ACETOACETATE DECARBOXYLASE (ADC) (YP_094708.1) FROM LEGIONELLA PNEUMOPHILA SUBSP. PNEUMOPHILA STR. PHILADELPHIA 1 AT 1.60 A RESOLUTION | YP_094708.1, ACETOACETATE DECARBOXYLASE (ADC), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
3c8w:C (ARG160) to (LYS172) CRYSTAL STRUCTURE OF ACETOACETATE DECARBOXYLASE (ADC) (YP_094708.1) FROM LEGIONELLA PNEUMOPHILA SUBSP. PNEUMOPHILA STR. PHILADELPHIA 1 AT 1.60 A RESOLUTION | YP_094708.1, ACETOACETATE DECARBOXYLASE (ADC), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, LYASE
3n9s:A (PRO43) to (MET56) CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE FROM HELICOBACTER PYLORI IN COMPLEX WITH N-(4-HYDROXYBUTYL)- GLYCOLOHYDROXAMIC ACID BIS- PHOSPHATE, A COMPETITIVE INHIBITOR | FBP ALDOLASE, CLASS II, INHIBITOR, LYASE, LYASE-LYASE INHIBITOR COMPLEX
3caw:A (LYS202) to (LYS211) CRYSTAL STRUCTURE OF O-SUCCINYLBENZOATE SYNTHASE FROM BDELLOVIBRIO BACTERIOVORUS LIGANDED WITH MG | STRUCTURAL GENOMICS, PSI-2, NYSGXRC, TARGET 9462A, O-SUCCINYLBENZOATE SYNTHASE, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, OXIDOREDUCTASE
4r8x:A (THR39) to (GLY61) CRYSTAL STRUCTURE OF A URICASE FROM BACILLUS FASTIDIOUS | BACILLUS FASTIDIOUS URICASE, FOLD, STABILITY, HYDROLASE
4r8x:D (THR39) to (GLY61) CRYSTAL STRUCTURE OF A URICASE FROM BACILLUS FASTIDIOUS | BACILLUS FASTIDIOUS URICASE, FOLD, STABILITY, HYDROLASE
4r99:A (THR39) to (GLY61) CRYSTAL STRUCTURE OF A URICASE FROM BACILLUS FASTIDIOUS | BACILLUS FASTIDIOUS URICASE, FOLD, STABILITY, HYDROLASE
4r99:B (THR39) to (GLY61) CRYSTAL STRUCTURE OF A URICASE FROM BACILLUS FASTIDIOUS | BACILLUS FASTIDIOUS URICASE, FOLD, STABILITY, HYDROLASE
4r99:C (THR39) to (GLY61) CRYSTAL STRUCTURE OF A URICASE FROM BACILLUS FASTIDIOUS | BACILLUS FASTIDIOUS URICASE, FOLD, STABILITY, HYDROLASE
4r99:D (THR39) to (GLY61) CRYSTAL STRUCTURE OF A URICASE FROM BACILLUS FASTIDIOUS | BACILLUS FASTIDIOUS URICASE, FOLD, STABILITY, HYDROLASE
3cce:J (LYS128) to (GLY140) STRUCTURE OF ANISOMYCIN RESISTANT 50S RIBOSOMAL SUBUNIT: 23S RRNA MUTATION U2535A | 23S RRNA MUTATION U2535A, RIBOSOME
4c1s:B (THR500) to (ARG522) GLYCOSIDE HYDROLASE FAMILY 76 (MANNOSIDASE) BT3792 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 | HYDROLASE, GUT MICROBIOTA
5fjn:A (PRO343) to (MET358) STRUCTURE OF L-AMINO ACID DEAMINASE FROM PROTEUS MYXOFACIENS IN COMPLEX WITH ANTHRANILATE | HYDROLASE, L-AMINO ACID DEAMINASE, FLAVOPROTEIN, FLAVOENZYME, MEMBRANE PROTEIN
5fjn:B (PRO343) to (MET358) STRUCTURE OF L-AMINO ACID DEAMINASE FROM PROTEUS MYXOFACIENS IN COMPLEX WITH ANTHRANILATE | HYDROLASE, L-AMINO ACID DEAMINASE, FLAVOPROTEIN, FLAVOENZYME, MEMBRANE PROTEIN
3ce9:B (ASP148) to (SER160) CRYSTAL STRUCTURE OF GLYCEROL DEHYDROGENASE (NP_348253.1) FROM CLOSTRIDIUM ACETOBUTYLICUM AT 2.37 A RESOLUTION | NP_348253.1, GLYCEROL DEHYDROGENASE, 3-DEHYDROQUINATE SYNTHASE, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, OXIDOREDUCTASE
3ndt:C (ASN83) to (GLY94) HIV-1 PROTEASE SAQUINAVIR:RITONAVIR 1:1 COMPLEX STRUCTURE | HYDROLASE, AIDS, ASPARTYL PROTEASE, CARBAMYLATION, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
3ndw:B (ASN83) to (GLY94) HIV-1 PROTEASE SAQUINAVIR:RITONAVIR 1:15 COMPLEX STRUCTURE | HIV-1 PROTEASE, HYDROLASE, AIDS, ASPARTYL PROTEASE, SAQUINAVIR, CARBAMYLATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ndx:B (ASN83) to (GLY94) HIV-1 PROTEASE SAQUINAVIR:RITONAVIR 1:50 COMPLEX STRUCTURE | HIV-1 PROTEASE, HYDROLASE, AIDS, ASPARTYL PROTEASE, SAQUINAVIR, CARBAMYLATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ngr:A (SER2) to (GLY18) CRYSTAL STRUCTURE OF LEISHMANIA NUCLEOSIDE DIPHOSPHATE KINASE B WITH UNORDERED NUCLEOTIDE-BINDING LOOP. | NDKB, PHOSPHATE ION, TRANSFERASE
3cjo:B (ILE19) to (SER36) CRYSTAL STRUCTURE OF KSP IN COMPLEX WITH INHIBITOR 30 | KSP, KSP-INHIBITOR COMPLEX, ATP-BINDING, CELL CYCLE, CELL DIVISION, COILED COIL, MICROTUBULE, MITOSIS, MOTOR PROTEIN, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN
3nk7:B (ALA5) to (THR22) STRUCTURE OF THE NOSIHEPTIDE-RESISTANCE METHYLTRANSFERASE S-ADENOSYL- L-METHIONINE COMPLEX | NOSIHEPTIDE, NOSIHEPTIDE-RESISTANCE METHYLTRANSFERASE, 23S RRNA METHYLTRANSFERASE, SAM, TRANSFERASE
3cms:A (GLY119) to (HIS144) ENGINEERING ENZYME SUB-SITE SPECIFICITY: PREPARATION, KINETIC CHARACTERIZATION AND X-RAY ANALYSIS AT 2.0-ANGSTROMS RESOLUTION OF VAL111PHE SITE-MUTATED CALF CHYMOSIN | HYDROLASE, ACID PROTEINASE
5fok:A (THR51) to (GLY64) CRYSTAL STRUCTURE OF THE SIDEROPHORE RECEPTOR PIUA FROM PSEUDOMONAS AERUGINOSA | METAL TRANSPORT, TONB-DEPENDENT RECEPTOR, SIDEROPHORE RECEPTOR, OUTER-MEMBRANE PROTEIN
4ri1:C (GLU158) to (GLN175) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI PSEUDAMINIC ACID BIOSYNTHESIS N -ACETYLTRANSFERASE PSEH COMPLEX WITH ACETYL-COA | GNAT FAMILY, N-ACETYL TRANSFERASE, ACETYL-COA, NONE, TRANSFERASE
3nnk:A (GLY122) to (ILE137) BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF A UREIDOGLYCINE AMINOTRANSFERASE IN THE KLEBSIELLA PNEUMONIAE URIC ACID CATABOLIC PATHWAY | AMINOTRANSFERASE, PLP-DEPENDENT, TRANSFERASE
3nnk:B (GLY122) to (ARG136) BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF A UREIDOGLYCINE AMINOTRANSFERASE IN THE KLEBSIELLA PNEUMONIAE URIC ACID CATABOLIC PATHWAY | AMINOTRANSFERASE, PLP-DEPENDENT, TRANSFERASE
3nnk:C (GLY122) to (ARG136) BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF A UREIDOGLYCINE AMINOTRANSFERASE IN THE KLEBSIELLA PNEUMONIAE URIC ACID CATABOLIC PATHWAY | AMINOTRANSFERASE, PLP-DEPENDENT, TRANSFERASE
3nnk:D (GLY122) to (ARG136) BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF A UREIDOGLYCINE AMINOTRANSFERASE IN THE KLEBSIELLA PNEUMONIAE URIC ACID CATABOLIC PATHWAY | AMINOTRANSFERASE, PLP-DEPENDENT, TRANSFERASE
3nnk:E (GLY122) to (ILE137) BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF A UREIDOGLYCINE AMINOTRANSFERASE IN THE KLEBSIELLA PNEUMONIAE URIC ACID CATABOLIC PATHWAY | AMINOTRANSFERASE, PLP-DEPENDENT, TRANSFERASE
3nnk:G (GLY122) to (ILE137) BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF A UREIDOGLYCINE AMINOTRANSFERASE IN THE KLEBSIELLA PNEUMONIAE URIC ACID CATABOLIC PATHWAY | AMINOTRANSFERASE, PLP-DEPENDENT, TRANSFERASE
3nnk:H (GLY122) to (ILE137) BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF A UREIDOGLYCINE AMINOTRANSFERASE IN THE KLEBSIELLA PNEUMONIAE URIC ACID CATABOLIC PATHWAY | AMINOTRANSFERASE, PLP-DEPENDENT, TRANSFERASE
3nnk:J (GLY122) to (ARG136) BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF A UREIDOGLYCINE AMINOTRANSFERASE IN THE KLEBSIELLA PNEUMONIAE URIC ACID CATABOLIC PATHWAY | AMINOTRANSFERASE, PLP-DEPENDENT, TRANSFERASE
3nnk:M (GLY122) to (ARG136) BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF A UREIDOGLYCINE AMINOTRANSFERASE IN THE KLEBSIELLA PNEUMONIAE URIC ACID CATABOLIC PATHWAY | AMINOTRANSFERASE, PLP-DEPENDENT, TRANSFERASE
3nnk:P (GLY122) to (ARG136) BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF A UREIDOGLYCINE AMINOTRANSFERASE IN THE KLEBSIELLA PNEUMONIAE URIC ACID CATABOLIC PATHWAY | AMINOTRANSFERASE, PLP-DEPENDENT, TRANSFERASE
3nnk:S (GLY122) to (ARG136) BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF A UREIDOGLYCINE AMINOTRANSFERASE IN THE KLEBSIELLA PNEUMONIAE URIC ACID CATABOLIC PATHWAY | AMINOTRANSFERASE, PLP-DEPENDENT, TRANSFERASE
4cak:B (GLY271) to (LYS302) THREE-DIMENSIONAL RECONSTRUCTION OF INTACT HUMAN INTEGRIN ALPHAIIBBETA3 IN A PHOSPHOLIPID BILAYER NANODISC | CELL ADHESION, INTEGRIN, SINGLE PARTICLE RECONSTRUCTION
5fr8:A (GLY37) to (LEU49) CRYSTAL STRUCTURE OF THE SIDEROPHORE RECEPTOR PIRA FROM ACINETOBACTER BAUMANNII | TRANSPORT PROTEIN, TONB-DEPENDENT RECEPTOR, OUTER-MEMBRANE PROTEIN
4cav:A (TYR395) to (ASN405) CRYSTAL STRUCTURE OF ASPERGILLUS FUMIGATUS N-MYRISTOYL TRANSFERASE IN COMPLEX WITH MYRISTOYL COA AND A BENZOFURAN LIGAND R0-09-4879 | TRANSFERASE, DRUG DISCOVERY
3npm:A (VAL122) to (THR148) CRYSTAL STRUCTURE OF THE C47A/A241C DISULFIDE-LINKED C6 ASPARTATE TRANSCARBAMOYLASE ENZYME | ASPARTATE TRANSCARBAMOYLASE, DISULFIDE BOND, PHOSPHATE, CATALYSIS, PRODUCT RELEASE, COOPERATIVITY, ALLOSTERY, TRANSFERASE
4cdh:A (GLN123) to (ASN142) CRYSTALLOGRAPHIC STRUCTURE OF THE HUMAN IGG1 ALPHA 2-6 SIALILATED FC-FRAGMENT | IMMUNE SYSTEM, C-LECTIN CRD, SIGN-R1, INMUNE SYSTEM, CAPSULAR POLYSACCHARIDE
4rnj:B (ASP181) to (LEU193) PAMORA PHOSPHODIESTERASE DOMAIN, APO FORM | EAL DOMAIN, PHOSPHODIESTERASE, C-DI-GMP, HYDROLASE
3co4:A (GLY86) to (ARG96) CRYSTAL STRUCTURE OF A CHITINASE FROM BACTEROIDES THETAIOTAOMICRON | CHITINASE, TIM-BARREL, 11092M, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, GLYCOSIDASE, HYDROLASE
5ftt:A (LYS108) to (PHE124) OCTAMERIC COMPLEX OF LATROPHILIN 3 (LEC, OLF) , UNC5D (IG, IG2, TSP1) AND FLRT2 (LRR) | SIGNALING PROTEIN, SIGNALLING PROTEIN, LEUCINE-RICH REPEAT, LRR, UNC5, UNC5D, FLRT2, LPHN3, LPHN, ADGRL, ADGRL3, ADGR, GPCR, UNCOORDINATED-5, NETRIN RECEPTOR, FLRT, LATROPHILIN, ADHESION, REPULSION, GUIDANCE, BETA PROPELLER, IMMUNOGLOBULIN, THROMBOSPONDIN, OLFACTOMEDIN, LECTIN, OCTAMER
3nu9:B (ASN183) to (GLY194) CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT I84V WITH ANTIVIRAL DRUG AMPRENAVIR | ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3nuh:B (MSE762) to (GLY782) A DOMAIN INSERTION IN E. COLI GYRB ADOPTS A NOVEL FOLD THAT PLAYS A CRITICAL ROLE IN GYRASE FUNCTION | GYRASE, TOPOISOMERASE, SUPERCOILING, SPECIALIZATION, ISOMERASE
3nuo:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT L90M WITH ANTIVIRAL DRUG AMPRENAVIR | ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5fv7:B (VAL31) to (LEU43) HUMAN FEN1 IN COMPLEX WITH AN N-HYDROXYUREA COMPOUND | HYDROLASE
4chg:C (ALA0) to (LEU12) CRYSTAL STRUCTURE OF VAPBC15 COMPLEX FROM MYCOBACTERIUM TUBERCULOSIS | TOXIN-ANTITOXIN COMPLEX, PIN DOMAIN
3ctm:A (HIS68) to (GLY82) CRYSTAL STRUCTURE OF A CARBONYL REDUCTASE FROM CANDIDA PARAPSILOSIS WITH ANTI-PRELOG STEREO-SPECIFICITY | ALCOHOL DEHYDROGENASE, CANDIDA PARAPSILOSIS, SHORT-CHAIN DEHYDROGENASES/REDUCTASES (SDR), X-RAY CRYSTALLOGRAPHY, OXIDOREDUCTASE
3ctm:G (HIS68) to (GLY82) CRYSTAL STRUCTURE OF A CARBONYL REDUCTASE FROM CANDIDA PARAPSILOSIS WITH ANTI-PRELOG STEREO-SPECIFICITY | ALCOHOL DEHYDROGENASE, CANDIDA PARAPSILOSIS, SHORT-CHAIN DEHYDROGENASES/REDUCTASES (SDR), X-RAY CRYSTALLOGRAPHY, OXIDOREDUCTASE
3nzw:T (HIS221) to (ILE240) CRYSTAL STRUCTURE OF THE YEAST 20S PROTEASOME IN COMPLEX WITH 2B | UBIQUITIN, PROTEIN DEGRADATION, N-TERMINAL NUCLEOPHILIC HYDROLASE, 19S REGULATORY PARTICLE, UBIQUITIN-TAGGED SUBSTRATES, CYTOSOL, NUCLEUS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4rvw:A (SER33) to (LYS45) STRUCTURE OF THE BACTERIAL ZN-TRANSPORTER ZNUD FROM NEISSERIA MENINGITIDIS (SOAKED WITH 20 MICROMOLAR ZINC) | OUTER MEMBRANE PROTEIN, ZINC TRANSPORTER, ZINC ACQUISITION, TONB DEPENDANT RECEPTOR, VACCINE CANDIDATE, TRANSPORT PROTEIN
3cy2:A (PRO125) to (GLU135) CRYSTAL STRUCTURE OF HUMAN PROTO-ONCOGENE SERINE THREONINE KINASE (PIM1) IN COMPLEX WITH A CONSENSUS PEPTIDE AND A BETA CARBOLINE LIGAND II | ONCOGENE, KINASE, SERINE-THREONINE, PIM1, STRUCTURAL GENOMICS CONSORTIUM, SGC, ALTERNATIVE INITIATION, ATP-BINDING, MANGANESE, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTO-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, HOST-VIRUS INTERACTION, VIRAL IMMUNOEVASION, VIRION, VIRULENCE
3cyx:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 MUTANT I50V AND INHIBITOR SAQUINAVIRA | DRUG RESISTANCE; HIV-1, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4coe:B (ASN183) to (GLY194) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, ENZYME
3o5u:A (ILE164) to (GLY186) CRYSTAL STRUCTURE OF 4-CHLOROCATECHOL DIOXYGENASE FROM RHODOCOCCUS OPACUS 1CP IN COMPLEX WITH PROTOCATECHUATE | BETA BARREL,OXIDOREDUCTASE, OXIDOREDUCTASE
3d1x:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 MUTANT I54M AND INHIBITOR SAQUINAVIR | DRUG RESISTANCE, HIV-1, I54M, FLAP MUTANT, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, VIRAL NUCLEOPROTEIN
3d1z:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 MUTANT I54M AND INHIBITOR DARUNAVIR | DRUG RESISTANCE; HIV-1, FLAP MUTANT, I54M, DARUNAVIR, HYDROLASE
3d20:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 MUTANT I54V AND INHIBITOR DARUNAVIA | DRUG RESISTANCE; HIV-1, I54V, FLAP MUTANT, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC-FINGER
4cpr:B (ASN183) to (GLY194) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
4cps:B (ASN183) to (GLY194) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
4cpt:B (ASN183) to (GLY194) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, HIV-1 PROTEASE, INHIBITOR, RATIONAL DRUG DESIGN, ENZYME
4cpu:B (ASN183) to (GLY194) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, HIV-1 PROTEASE, INHIBITOR, RATIONAL DRUG DESIGN
4cpw:B (ASN183) to (GLY194) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
4cqa:A (GLY475) to (LYS482) PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE (DHODH) IN COMPLEX WITH IDI-6273 | OXIDOREDUCTASE, DHODH
4cqa:B (GLY475) to (LYS482) PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE (DHODH) IN COMPLEX WITH IDI-6273 | OXIDOREDUCTASE, DHODH
5g1n:A (ARG2040) to (GLY2068) ASPARTATE TRANSCARBAMOYLASE DOMAIN OF HUMAN CAD BOUND TO PALA | TRANSFERASE, DE NOVO PYRIMIDINE SYNTHESIS, TRANSCARBAMOYLASE, TRANSCARBAMYLASE, CAD, CARBAMOYL PHOSPHATE SYNTHETASE, DIHYDROOROTASE, COOPERATIVITY
5g1n:E (ARG2040) to (GLY2068) ASPARTATE TRANSCARBAMOYLASE DOMAIN OF HUMAN CAD BOUND TO PALA | TRANSFERASE, DE NOVO PYRIMIDINE SYNTHESIS, TRANSCARBAMOYLASE, TRANSCARBAMYLASE, CAD, CARBAMOYL PHOSPHATE SYNTHETASE, DIHYDROOROTASE, COOPERATIVITY
5g1o:E (ARG2040) to (GLY2068) ASPARTATE TRANSCARBAMOYLASE DOMAIN OF HUMAN CAD IN APO FORM | TRANSFERASE, DE NOVO PYRIMIDINE SYNTHESIS, TRANSCARBAMOYLASE, TRANSCARBAMYLASE, CAD, CARBAMOYL PHOSPHATE SYNTHETASE, DIHYDROOROTASE, COOPERATIVITY
3o99:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD13 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5g1p:C (ARG2040) to (GLY2068) ASPARTATE TRANSCARBAMOYLASE DOMAIN OF HUMAN CAD BOUND TO CARBAMOYL PHOSPHATE | TRANSFERASE, DE NOVO PYRIMIDINE SYNTHESIS, TRANSCARBAMOYLASE, TRANSCARBAMYLASE, CAD, CARBAMOYL PHOSPHATE SYNTHETASE, DIHYDROOROTASE, COOPERATIVITY
3o9h:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH KD26 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4cr3:S (LYS400) to (SER415) DEEP CLASSIFICATION OF A LARGE CRYO-EM DATASET DEFINES THE CONFORMATIONAL LANDSCAPE OF THE 26S PROTEASOME | HYDROLASE, AAA-ATPASE, ATP-ANALOG, CLASSIFICATION
4s3i:A (ILE3) to (LEU17) CRYSTAL STRUCTURE OF BETA CLAMP FROM HELICOBACTER PYLORI | SLIDING DNA CLAMP, PROCESSIVITY PROMOTING FACTOR, DNA REPLICATION, DNA, TRANSFERASE
5g4f:A (LEU630) to (MET652) STRUCTURE OF THE ADP-BOUND VAT COMPLEX | HYDROLASE, VAT, PROTEASOME, PROTEIN DYNAMICS, UNFOLDASE, CONFORMATIONS, AAA ATPASE
3d6g:A (GLN342) to (ASN361) FC FRAGMENT OF IGG1 (HERCEPTIN) WITH PROTEIN-A MIMETIC PEPTIDE DENDRIMER LIGAND. | FC FRAGMENT, IGG1, GLYCOSILATED PROTEIN, PROTEIN A MIMETIC PEPTIDE DENDRIMER LIGAND, GLYCOPROTEIN, IMMUNOGLOBULIN C REGION, IMMUNOGLOBULIN DOMAIN, SECRETED, IMMUNE SYSTEM
4tm0:C (VAL339) to (GLY356) KUTZNERIA SP. 744 ORNITHINE N-HYDROXYLASE, KTZI-FADRED-OX-NADP+-L-ORN | HYDROXYLASE, FLAVIN, MONOOXYGENASE, ORNITHINE
3obe:B (LYS237) to (GLN251) CRYSTAL STRUCTURE OF A SUGAR PHOSPHATE ISOMERASE/EPIMERASE (BDI_3400) FROM PARABACTEROIDES DISTASONIS ATCC 8503 AT 1.70 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, ISOMERASE
3oce:D (ILE390) to (VAL412) CRYSTAL STRUCTURE OF FUMARATE LYASE:DELTA CRYSTALLIN FROM BRUCELLA MELITENSIS BOUND TO COBALT | FUMARATE LYASE, FUMARASE, BRUCELLOSIS, ORCHITIS, EPIDIDYMITIS, MASTITIS, DEHYDRATION OF FUMARATE TO MALATE, KREB'S CYCLE, CITRIC ACID CYCLE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, LYASE
3dcr:B (ASN83) to (GLY94) X-RAY STRUCTURE OF HIV-1 PROTEASE AND HYDRATED FORM OF KETOMETHYLENE ISOSTERE INHIBITOR | HIV-1 PROTEASE, HOMODIMER, BETA-TURN, BETA-STRAND, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ogl:L (SER388) to (THR400) STRUCTURE OF COI1-ASK1 IN COMPLEX WITH JA-ISOLEUCINE AND THE JAZ1 DEGRON | LEUCINE-RICH REPEATS, UBIQUITIN LIGASE, SCF, PROTEIN BINDING
4tsl:A (GLN125) to (ARG140) CRYSTAL STRUCTURE OF FRAC WITH POC BOUND (CRYSTAL FORM I) | TOXIN, ACTINOPORIN, PORE-FORMING TOXIN, MEMBRANE LIPIDS, PHOSPHOCHOLINE, LIPID-PROTEIN INTERACTION
4tsl:B (GLN125) to (ARG140) CRYSTAL STRUCTURE OF FRAC WITH POC BOUND (CRYSTAL FORM I) | TOXIN, ACTINOPORIN, PORE-FORMING TOXIN, MEMBRANE LIPIDS, PHOSPHOCHOLINE, LIPID-PROTEIN INTERACTION
4tsn:C (GLN125) to (ARG140) CRYSTAL STRUCTURE OF FRAC WITH POC BOUND (CRYSTAL FORM II) | TOXIN, ACTINOPORIN, PORE-FORMING TOXIN, MEMBRANE LIPIDS, PHOSPHOCHOLINE, LIPID-PROTEIN INTERACTION
4tsp:A (GLN125) to (ARG140) CRYSTAL STRUCTURE OF FRAC WITH DHPC BOUND (CRYSTAL FORM II) | TOXIN, ACTINOPORIN PORE-FORMING TOXIN, MEMBRANE, LIPIDS PHOSPHOCHOLINE, LIPID-PROTEIN INTERACTION
3oh1:A (LEU218) to (ALA234) PROTEIN STRUCTURE OF USP FROM L. MAJOR BOUND TO URIDINE-5'- DIPHOSPHATE-GALACTURONIC ACID | LEFT HANDED BETA HELIX, ROSSMANN FOLD, UDP SUGAR PYROPHOSPHORYLASE, TRANSFERASE
3oh4:A (LEU218) to (ALA234) PROTEIN STRUCTURE OF USP FROM L. MAJOR BOUND TO URIDINE-5'-DIPHOSPHATE GLUCOSE | LEFT HANDED BETA HELIX, ROSSMANN FOLD, UDP SUGAR PYROPHOSPHORYLASE, TRANSFERASE
4d18:F (VAL41) to (GLU62) CRYSTAL STRUCTURE OF THE COP9 SIGNALOSOME | SIGNALING PROTEIN, PCI COMPLEX, CSN, SGN, MPN DOMAIN,
3di1:A (ASN142) to (LEU153) CRYSTAL STRUCTURE OF THE STAPHYLOCOCCUS AUREUS DIHYDRODIPICOLINATE SYNTHASE-PYRUVATE COMPLEX | DIHYDRODIPICOLINATE SYNTHASE, LYSINE BIOSYNTHESIS, FEEDBACK INHIBITION, PING-PONG MECHANISM, AMINO-ACID BIOSYNTHESIS, DIAMINOPIMELATE BIOSYNTHESIS, LYASE, SCHIFF BASE
4d2n:B (GLN342) to (ASN361) CRYSTAL STRUCTURE OF DEGLYCOSYLATED SERUM-DERIVED HUMAN IGG4 FC | IMMUNE SYSTEM, IGG, IMMUNOGLOBULIN, IGG1
4d2n:C (GLN342) to (ASN361) CRYSTAL STRUCTURE OF DEGLYCOSYLATED SERUM-DERIVED HUMAN IGG4 FC | IMMUNE SYSTEM, IGG, IMMUNOGLOBULIN, IGG1
3ojw:A (HIS601) to (ARG613) DISULFIDE CROSSLINKED CYTOCHROME P450 REDUCTASE INACTIVE | CYTOCHROME P450 REDUCTASE, CYPOR, DISULFIDE CROSSLINKED, INACTIVE, NADP+ FREE, OXIDOREDUCTASE
3ojx:A (HIS601) to (ARG613) DISULFIDE CROSSLINKED CYTOCHROME P450 REDUCTASE INACTIVE | CYTOCHROME P450 REDUCTASE, CYPOR, DISULFIDE CROSSLINKED, INACTIVE, OXIDOREDUCTASE
3dkv:A (ARG79) to (VAL90) CRYSTAL STRUCTURE OF ADENYLATE KINASE VARIANT AKLSE1 | PHOSPHOTRANSFERASE, ZINC COORDINATION, ATP-BINDING, KINASE, METAL- BINDING, NUCLEOTIDE BIOSYNTHESIS, NUCLEOTIDE-BINDING, TRANSFERASE
4tvh:B (ASN83) to (GLY94) HIV PROTEASE (PR) DIMER IN CLOSED FORM WITH TL-3 IN ACTIVE SITE AND FRAGMENT AK-2097 IN THE OUTSIDE/TOP OF FLAP | HIV PROTEASE, ALLOSTERY, FRAGMENT BINDING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3do3:B (GLN342) to (ASN361) HUMAN 1GG1 FC FRAGMENT, 2.5 ANGSTROM STRUCTURE | IMMUNOGLOBULIN FOLD, GLYCOPROTEIN, IMMUNOGLOBULIN C REGION, IMMUNOGLOBULIN DOMAIN, SECRETED, IMMUNE SYSTEM
4d8t:A (ILE250) to (GLY260) CRYSTAL STRUCTURE OF D-CYSTEINE DESULFHYDRASE FROM SALMONELLA TYPHIMURIUM AT 2.2 A RESOLUTION | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4d8t:B (ILE250) to (GLY260) CRYSTAL STRUCTURE OF D-CYSTEINE DESULFHYDRASE FROM SALMONELLA TYPHIMURIUM AT 2.2 A RESOLUTION | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4d8t:C (ILE250) to (GLY260) CRYSTAL STRUCTURE OF D-CYSTEINE DESULFHYDRASE FROM SALMONELLA TYPHIMURIUM AT 2.2 A RESOLUTION | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4d8t:D (ILE250) to (GLY260) CRYSTAL STRUCTURE OF D-CYSTEINE DESULFHYDRASE FROM SALMONELLA TYPHIMURIUM AT 2.2 A RESOLUTION | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4u10:A (PRO50) to (GLY69) PROBING THE STRUCTURE AND MECHANISM OF DE-N-ACETYLASE FROM AGGREGATIBACTER ACTINOMYCETEMCOMITANS | DE-N-ACETYLASE, AGGREGATIBACTER ACTINOMYCETEMCOMITANS, ZINC INHIBITION
4u10:B (PRO50) to (GLY69) PROBING THE STRUCTURE AND MECHANISM OF DE-N-ACETYLASE FROM AGGREGATIBACTER ACTINOMYCETEMCOMITANS | DE-N-ACETYLASE, AGGREGATIBACTER ACTINOMYCETEMCOMITANS, ZINC INHIBITION
4d8w:A (ILE250) to (GLY260) SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE SOAKED WITH D-CYS SHOWS PYRUVATE BOUND 4 A AWAY FROM ACTIVE SITE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4d8w:B (ILE250) to (GLY260) SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE SOAKED WITH D-CYS SHOWS PYRUVATE BOUND 4 A AWAY FROM ACTIVE SITE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4d8w:C (ILE250) to (GLY260) SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE SOAKED WITH D-CYS SHOWS PYRUVATE BOUND 4 A AWAY FROM ACTIVE SITE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4d96:B (ILE250) to (GLY260) D-CYSTEINE DESULFHYDRASE FROM SALMONELLA TYPHIMURIUM COMPLEXED WITH 1- AMINO-1-CARBOXYCYCLOPROPANE (ACC) | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT LIKE FAMILY, PLP DEPENDENT ENZYME, LYASE
4d97:A (ILE250) to (GLY260) SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE WITH D-SER BOUND AT ACTIVE SITE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4d97:B (ILE250) to (GLY260) SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE WITH D-SER BOUND AT ACTIVE SITE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4d97:C (ILE250) to (GLY260) SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE WITH D-SER BOUND AT ACTIVE SITE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4d99:A (ILE250) to (GLY260) SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE WITH L-SER BOUND NON- COVALENTLY AT THE ACTIVE SITE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4d99:B (ILE250) to (GLY260) SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE WITH L-SER BOUND NON- COVALENTLY AT THE ACTIVE SITE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4d99:D (ILE250) to (GLY260) SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE WITH L-SER BOUND NON- COVALENTLY AT THE ACTIVE SITE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT- LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY, LYASE
4d9c:A (ILE250) to (GLY260) PMP BOUND FORM OF SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE OBTAINED AFTER CO-CRYSTALLIZATION WITH L-CYCLOSERINE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT LIKE FAMILY, LYASE
4d9c:B (ILE250) to (GLY260) PMP BOUND FORM OF SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE OBTAINED AFTER CO-CRYSTALLIZATION WITH L-CYCLOSERINE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT LIKE FAMILY, LYASE
4d9c:C (ILE250) to (GLY260) PMP BOUND FORM OF SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE OBTAINED AFTER CO-CRYSTALLIZATION WITH L-CYCLOSERINE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT LIKE FAMILY, LYASE
4d9c:D (ILE250) to (GLY260) PMP BOUND FORM OF SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE OBTAINED AFTER CO-CRYSTALLIZATION WITH L-CYCLOSERINE | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT LIKE FAMILY, LYASE
4d9e:A (ILE250) to (GLY260) D-CYSTEINE DESULFHYDRASE FROM SALMONELLA TYPHIMURIUM COMPLEXED WITH L- CYCLOSERINE (LCS) | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT LIKE FAMILY, PLP DEPENDENT ENZYME, LYASE
4d9e:B (ILE250) to (GLY260) D-CYSTEINE DESULFHYDRASE FROM SALMONELLA TYPHIMURIUM COMPLEXED WITH L- CYCLOSERINE (LCS) | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT LIKE FAMILY, PLP DEPENDENT ENZYME, LYASE
4d9e:C (ILE250) to (GLY260) D-CYSTEINE DESULFHYDRASE FROM SALMONELLA TYPHIMURIUM COMPLEXED WITH L- CYCLOSERINE (LCS) | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT LIKE FAMILY, PLP DEPENDENT ENZYME, LYASE
4d9e:D (ILE250) to (GLY260) D-CYSTEINE DESULFHYDRASE FROM SALMONELLA TYPHIMURIUM COMPLEXED WITH L- CYCLOSERINE (LCS) | FOLD TYPE II PLP-DEPENDENT ENZYME, TRYPTOPHAN SYNTHASE BETA SUBUNIT LIKE FAMILY, PLP DEPENDENT ENZYME, LYASE
4dbp:A (PRO706) to (TYR718) MYOSIN VI NUCLEOTIDE-FREE (MDINSERT2) D179Y CRYSTAL STRUCTURE | MOTOR PROTEIN, MOTOR PROTEIN-CALCIUM BINDING PROTEIN COMPLEX
5hc9:A (ASP189) to (GLY207) THERMOTOGA MARITIMA CCA-ADDING ENZYME COMPLEXED WITH TRNA_CCA | TRNA, CCA-ADDING ENZYME, TRANSFERASE
3oty:B (ASN83) to (GLY94) MDR769 HIV-1 PROTEASE COMPLEXED WITH RT/RH HEPTA-PEPTIDE | MDR HIV-1 PROTEASE, INHIBITOR, DRUG RESISTANCE, SUBSTRATE ENVELOPE, HIV-1 PROTEASE, PROTEASE, SUBSTRATE PEPTIDE, HYDROLASE, HYDROLASE- PEPTIDE COMPLEX
3oua:A (ASN83) to (GLY94) MDR769 HIV-1 PROTEASE COMPLEXED WITH P1/P6 HEPTA-PEPTIDE | MDR HIV-1 PROTEASE, INHIBITOR, DRUG RESISTANCE, SUBSTRATE ENVELOPE, HIV-1 PROTEASE, PROTEASE, P1/P6 SUBSTRATE PEPTIDE, NONE, HYDROLASE, HYDROLASE-PEPTIDE COMPLEX
3oua:B (ASN83) to (GLY94) MDR769 HIV-1 PROTEASE COMPLEXED WITH P1/P6 HEPTA-PEPTIDE | MDR HIV-1 PROTEASE, INHIBITOR, DRUG RESISTANCE, SUBSTRATE ENVELOPE, HIV-1 PROTEASE, PROTEASE, P1/P6 SUBSTRATE PEPTIDE, NONE, HYDROLASE, HYDROLASE-PEPTIDE COMPLEX
4del:A (ASP47) to (SER61) ACTIVE SITE LOOP DYNAMICS OF A CLASS IIA FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE FROM M. TUBERCULOSIS | CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE, ZINC ENZYME, DIHYDROXYACETONE, GLYCERALDEHYDE-3-PHOSPHATE, ALDOL CONDENSATION, GLYCOLYSIS, LYASE, METAL-BINDING, PHOSPHOGLYCOLOHYDROXAMATE
3oxv:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 I50V, A71 PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR AMPRENAVIR. | HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, DRUG RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3oxw:D (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 I50V, A71V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR DARUNAVIR | HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, DRUG RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3oxx:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 I50V, A71V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR ATAZANAVIR | HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3oxx:D (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 I50V, A71V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR ATAZANAVIR | HIV-1 PROTEASE, INHIBITOR RESISTANCE, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4dfe:A (LEU186) to (ILE199) CRYSTAL STRUCTURE OF 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III FROM BURKHOLDERIA XENOVORANS | SSGCID, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
4dfe:C (LEU186) to (ILE199) CRYSTAL STRUCTURE OF 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III FROM BURKHOLDERIA XENOVORANS | SSGCID, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
4dfg:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE WITH CYCLOPENTYLTETRAHYDRO- FURANYL URETHANES AS P2-LIGAND, GRL-0249A | ASPARTIC ACID PROTEASE, HIV-1 PROTEASE INHIBITOR GRL-0249A, CYCLOPENTYLTETRAHYDRO- FURANYL URETHANES P2-LIGANDS, WILD-TYPE HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4dfg:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE WITH CYCLOPENTYLTETRAHYDRO- FURANYL URETHANES AS P2-LIGAND, GRL-0249A | ASPARTIC ACID PROTEASE, HIV-1 PROTEASE INHIBITOR GRL-0249A, CYCLOPENTYLTETRAHYDRO- FURANYL URETHANES P2-LIGANDS, WILD-TYPE HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3oz2:A (GLY45) to (ASP57) CRYSTAL STRUCTURE OF A GERANYLGERANYL BACTERIOCHLOROPHYLL REDUCTASE- LIKE (TA0516) FROM THERMOPLASMA ACIDOPHILUM AT 1.60 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, FLAVOPROTEIN, OXIDOREDUCTASE
4djo:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH MKP56 | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3p2z:A (THR459) to (HIS489) POLO-LIKE KINASE I POLO-BOX DOMAIN IN COMPLEX WITH PLHSPTA PHOSPHOPEPTIDE FROM PBIP1 | PHOSPHOPROTEIN BINDING DOMAIN, PLK1, KINASE, TRANSFERASE
3p2z:A (ASP558) to (LEU591) POLO-LIKE KINASE I POLO-BOX DOMAIN IN COMPLEX WITH PLHSPTA PHOSPHOPEPTIDE FROM PBIP1 | PHOSPHOPROTEIN BINDING DOMAIN, PLK1, KINASE, TRANSFERASE
3p7i:A (PRO245) to (ASN272) CRYSTAL STRUCTURE OF ESCHERICHIA COLI PHND IN COMPLEX WITH 2- AMINOETHYL PHOSPHONATE | PHOSPHONATE BINDING PROTEIN, TRANSPORT PROTEIN
5hnz:K (ASN24) to (GLY42) STRUCTURAL BASIS OF BACKWARDS MOTION IN KINESIN-14: PLUS-END DIRECTED NKN669 IN THE NUCLEOTIDE-FREE STATE | KINESIN, KINESIN-14, MICROTUBULE, ATPASE, STRUCTURAL PROTEIN-MOTOR PROTEIN COMPLEX
3p83:D (ARG58) to (ARG72) STRUCTURE OF THE PCNA:RNASE HII COMPLEX FROM ARCHAEOGLOBUS FULGIDUS. | DNA CLAMP, RNASE H FOLD, CLEAVES RNA/DNA HYBRIDS, NUCLEUS, HYDROLASE- DNA BINDING PROTEIN COMPLEX
4dqb:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH DRV | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3paj:A (ALA180) to (GLY192) 2.00 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A QUINOLINATE PHOSPHORIBOSYLTRANSFERASE FROM VIBRIO CHOLERAE O1 BIOVAR ELTOR STR. N16961 | TIM BARREL, NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE, PYRIDINE- 2,3- DICARBOXYLATE, 5-PHOSPHO-ALPHA-D-RIBOSE 1-DIPHOSPHATE, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, GUINOLINATE PHOSPHORIBOSYLTRANSFERASE, DE NOVO SYNTHESIS OF NAD, TRANSFERASE
3pbe:A (ASP242) to (GLY282) CRYSTAL STRUCTURE OF THE MUTANT W207F OF HUMAN SECRETORY GLUTAMINYL CYCLASE | ALPHA/BETA PROTEIN, ALPHA/BETA-MIXED FOLD, GLUTAMINYL CYCLASE, SECRETORY PATHWAY, TRANSFERASE
3pbe:B (LEU243) to (GLY282) CRYSTAL STRUCTURE OF THE MUTANT W207F OF HUMAN SECRETORY GLUTAMINYL CYCLASE | ALPHA/BETA PROTEIN, ALPHA/BETA-MIXED FOLD, GLUTAMINYL CYCLASE, SECRETORY PATHWAY, TRANSFERASE
5hxr:A (MET252) to (LYS276) STRUCTURAL MECHANISMS OF EXTRACELLULAR ION EXCHANGE AND INDUCED BINDING-SITE OCCLUSION IN THE SODIUM-CALCIUM EXCHANGER NCX_MJ SOAKED WITH 2.5 MM NA+ AND 10MM CA2+ | NA+/CA2+ EXCHANGE, CALCIUM SIGNALLING, MEMBRANE TRANSPORTER, INDUCED CONFORMATIONAL CHANGE, MEMBRANE PROTEIN
3pdn:A (GLY194) to (ASN205) CRYSTAL STRUCTURE OF SMYD3 IN COMPLEX WITH METHYLTRANSFERASE INHIBITOR SINEFUNGIN | ROSSMANN FOLD, ZINC FINGER, METHYLTRANSFERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5i0i:C (GLY98) to (THR110) CRYSTAL STRUCTURE OF MYOSIN X MOTOR DOMAIN WITH 2IQ MOTIFS IN PRE- POWERSTROKE STATE | MYOSIN, MOTOR DOMAIN, MOLECULAR MOTOR, PRE-POWERSTROCKE STATE, MOTILITY, MOTOR PROTEIN
5i2m:A (GLY256) to (ALA293) CRYSTAL STRUCTURE OF VSV-INDIANA (MUDD-SUMMERS STRAIN) GLYCOPROTEIN UNDER ITS ACIDIC CONFORMATION | MEMBRANE, LIPOPROTEIN, GLYCOPROTEIN, TRANSMEMBRANE, ENVELOPE PROTEIN, MEMBRANE PROTEIN
3phv:A (ASN83) to (GLY94) X-RAY ANALYSIS OF HIV-1 PROTEINASE AT 2.7 ANGSTROMS RESOLUTION CONFIRMS STRUCTURAL HOMOLOGY AMONG RETROVIRAL ENZYMES | HYDROLASE, ASPARTIC PROTEINASE
4un0:C (ASP817) to (GLY827) CRYSTAL STRUCTURE OF THE HUMAN CDK12-CYCLINK COMPLEX | TRANSFERASE
4dz4:A (ILE208) to (GLU218) X-RAY CRYSTAL STRUCTURE OF A HYPOTHETICAL AGMATINASE FROM BURKHOLDERIA THAILANDENSIS | AGMATINASE, HYDROLASE
4dz4:B (ILE208) to (GLU218) X-RAY CRYSTAL STRUCTURE OF A HYPOTHETICAL AGMATINASE FROM BURKHOLDERIA THAILANDENSIS | AGMATINASE, HYDROLASE
4dz4:C (ILE208) to (GLY220) X-RAY CRYSTAL STRUCTURE OF A HYPOTHETICAL AGMATINASE FROM BURKHOLDERIA THAILANDENSIS | AGMATINASE, HYDROLASE
4dz4:D (ILE208) to (HIS219) X-RAY CRYSTAL STRUCTURE OF A HYPOTHETICAL AGMATINASE FROM BURKHOLDERIA THAILANDENSIS | AGMATINASE, HYDROLASE
4dz4:E (ILE208) to (GLU218) X-RAY CRYSTAL STRUCTURE OF A HYPOTHETICAL AGMATINASE FROM BURKHOLDERIA THAILANDENSIS | AGMATINASE, HYDROLASE
4dz4:F (ILE208) to (GLU218) X-RAY CRYSTAL STRUCTURE OF A HYPOTHETICAL AGMATINASE FROM BURKHOLDERIA THAILANDENSIS | AGMATINASE, HYDROLASE
4e03:A (ARG163) to (GLY179) STRUCTURE OF PARF-ADP FORM 2 | PARTITION, SEGREGATION, MULTIDRUG RESISTANCE, DEVIANT WALKER BOX, DNA SEGREGATION, UNKNOWN FUNCTION
4uoh:A (GLU4) to (GLY18) CRYSTALLOGRAPHIC STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE FROM LITOPENAEUS VANNAMEI COMPLEXED WITH ADP | TRANSFERASE, BINARY, COMPLEX, ADP, PURINE, WHITE-SHRIMP, BINDING SITE, NUCLEOTIDE
5i84:F (TYR319) to (LYS336) STRUCTURE OF THE XANTHOMONAS CITRI PHOSPHATE-BINDING PROTEIN PHOX | ABC TRANSPORTER, PERIPLASMIC-BINDING PROTEIN, PHOSPHATE-BINDING PROTEIN, PHOX, TRANSPORT PROTEIN
4e4k:B (GLN345) to (LEU356) CRYSTAL STRUCTURE OF PPARGAMMA WITH THE LIGAND JO21 | BUNDLE OF ALPHA-HELICES AND A SMALL FOUR-STRANDED BETA-SHEET, TRANSCRIPTION FACTOR, TRANSCRIPTION
4urk:A (TYR757) to (SER777) PI3KG IN COMPLEX WITH AZD6482 | TRANSFERASE, LIPID KINASE
3pvw:A (ALA218) to (GLN231) BOVINE GRK2 IN COMPLEX WITH GBETAGAMMA SUBUNITS AND A SELECTIVE KINASE INHIBITOR (CMPD103A) | TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, INHIBITOR, MEMBRANE, TRANSFERASE-SIGNALING PROTEIN-INHIBITOR COMPLEX
3pwr:B (ASN183) to (GLY194) HIV-1 PROTEASE MUTANT L76V COMPLEXED WITH SAQUINAVIR | HIV-1, PROTEASE, MUTATION L76V, SAQUINAVIR, HYDROLASE, HYDROLASE- HYDROLASE INHIBITOR COMPLEX
4ejk:B (ASN83) to (GLY94) HIV PROTEASE (PR) DIMER IN CLOSED FORM WITH PEPSTATIN IN ACTIVE SITE AND FRAGMENT 1F1-N IN THE OUTSIDE/TOP OF FLAP | APO PROTEASE, ALLOSTERY, FRAGMENT BINDING, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4el1:A (MET356) to (LYS366) CRYSTAL STRUCTURE OF OXIDIZED HPDI (ABB'XA') | ABB'A' DOMAINS, "CGHC" ACTIVE SITES, HORSESHOE SHAPE, ENZYME, A REDOX-REGULATED CHAPERONE, ENDOPLASMIC RETICULUM, CHAPERONE
3q4z:A (SER419) to (ARG438) STRUCTURE OF UNPHOSPHORYLATED PAK1 KINASE DOMAIN | KINASE DOMAIN, SIGNALLING PATHWAY, TRANSFERASE
5itz:A (GLN372) to (MET398) CRYSTAL STRUCTURE OF THE SAC DOMAIN OF CPAP IN A COMPLEX WITH TUBULIN AND DARPIN | TUBULIN, CPAP, CENTRIOLE, STRUCTURAL PROTEIN
3q6j:B (LYS176) to (GLU207) STRUCTURAL BASIS FOR CARBON DIOXIDE BINDING BY 2-KETOPROPYL COENZYME M OXIDOREDUCTASE/CARBOXYLASE | DISULFIDE, CARBON DIOXIDE, COENZYME M, FAD, NADP, OXIDOREDUCTASE, CARBOXYLASE
4es9:A (ASP179) to (ALA191) CRYSTAL STRUCTURE OF THE ADHESIN DOMAIN OF EPF FROM STREPTOCOCCUS PYOGENES IN P21 | CARBOHYDRATE-BINDING MODULE, FIBRONECTIN-LIKE DOMAIN, CELL ADHESION
4es9:C (ASP179) to (ALA191) CRYSTAL STRUCTURE OF THE ADHESIN DOMAIN OF EPF FROM STREPTOCOCCUS PYOGENES IN P21 | CARBOHYDRATE-BINDING MODULE, FIBRONECTIN-LIKE DOMAIN, CELL ADHESION
4es9:D (ASP179) to (ALA191) CRYSTAL STRUCTURE OF THE ADHESIN DOMAIN OF EPF FROM STREPTOCOCCUS PYOGENES IN P21 | CARBOHYDRATE-BINDING MODULE, FIBRONECTIN-LIKE DOMAIN, CELL ADHESION
5ivr:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH METHYL N-[(1S)-1-[[2- [(3S)-3-[(4-AMINOPHENYL)METHYLAMINO]-4-HYDROXY- BUTYL]PHENYL]CARBAMOYL]-2,2-DIPHENYL-ETHYL]CARBAMATE | HIV, PROTEASE, HYDROLASE-INHIBITOR COMPLEX
5ivs:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH METHYL N-[(1S)-1- BENZHYDRYL-2-[2-[2-[(2R,5S)-5-(BENZYLCARBAMOYLOXYMETHYL)MORPHOLIN-2- YL]ETHYL]ANILINO]-2-OXO-ETHYL]CARBAMATE | HIV, PROTEASE, HYDROLASE-INHIBITOR COMPLEX
5ivt:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH [(1S)-1-[(S)-(4- CHLOROPHENYL)-(3,5-DIFLUOROPHENYL)METHYL]-2-[[5-FLUORO-4-[2-[(2R,5S)- 5-(2,2,2-TRIFLUOROETHYLCARBAMOYLOXYMETHYL)MORPHOLIN-4-IUM-2- YL]ETHYL]PYRIDIN-1-IUM-3-YL]AMINO]-2-OXO-ETHYL]AMMONIUM | HIV, PROTEASE, HYDROLASE-INHIBITOR COMPLEX
3q8n:A (ARG16) to (ALA37) CRYSTAL STRUCTURE OF 4-AMINOBUTYRATE TRANSAMINASE FROM MYCOBACTERIUM SMEGMATIS | SSGCID, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, TRANSFERASE
4f04:A (VAL122) to (THR148) A SECOND ALLOSTERIC SITE IN E. COLI ASPARTATE TRANSCARBAMOYLASE: R- STATE ATCASE WITH UTP BOUND | ALLOSTERIC REGULATION, ATCASE, TRANSFERASE
4f04:C (PRO123) to (THR148) A SECOND ALLOSTERIC SITE IN E. COLI ASPARTATE TRANSCARBAMOYLASE: R- STATE ATCASE WITH UTP BOUND | ALLOSTERIC REGULATION, ATCASE, TRANSFERASE
3qe2:A (HIS604) to (ASP615) CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 REDUCTASE | CYPOR, CYTOCHROME P450 REDUCTASE, ANTLEY-BIXLER SYNDROME, FLAVOPROTEIN, FMN, FAD, NADPH, OXIDOREDUCTASE
3qe2:B (HIS604) to (ASP615) CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 REDUCTASE | CYPOR, CYTOCHROME P450 REDUCTASE, ANTLEY-BIXLER SYNDROME, FLAVOPROTEIN, FMN, FAD, NADPH, OXIDOREDUCTASE
3qfr:B (HIS604) to (ARG616) CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 REDUCTASE (R457H MUTANT) | NADPH-CYTOCHROME P450 REDUCTASE, FLAVOPROTEIN, ANTLEY-BIXLER SYNDROME, FAD, FMN, NADPH, OXIDOREDUCTASE
3qfs:A (HIS604) to (ARG616) CRYSTAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE (FAD/NADPH DOMAIN) | NADPH-CYTOCHROME P450 REDUCTASE, FLAVOPROTEIN, FAD, NADPH, OXIDOREDUCTASE
3qft:A (HIS604) to (ARG616) CRYSTAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE (FAD/NADPH DOMAIN AND R457H MUTANT) | NADPH-CYTOCHROME P450 REDUCTASE, FLAVOPROTEIN, ANTLEY-BIXLER SYNDROME, FAD, NADPH, OXIDOREDUCTASE
4f74:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF ACTIVE HIV-1 PROTEASE IN COMPLEX WITH THE N TERMINAL PRODUCT OF THE SUBSTRATE MA-CA. | HIV-1 PROTEASE, SUBSTRATE COMPLEX, AIDS, PRODUCT COMPLEX, ASPARTYL PROTEASE, HYDROLASE, HYDROLASE-HYDROLASE PRODUCT COMPLEX
3qm3:C (PRO55) to (GLY70) 1.85 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF FRUCTOSE-BISPHOSPHATE ALDOLASE (FBA) FROM CAMPYLOBACTER JEJUNI | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, TIM BETA/ALPHA-BARREL, LYASE
4uwj:A (TYR395) to (ASN405) CRYSTAL STRUCTURE OF ASPERGILLUS FUMIGATUS N-MYRISTOYL TRANSFERASE IN COMPLEX WITH MYRISTOYL COA AND A CAPPED PYRAZOLE SULPHONAMIDE LIGAND | TRANSFERASE, DRUG DISCOVERY
4v1a:c (GLU121) to (PHE155) STRUCTURE OF THE LARGE SUBUNIT OF THE MAMMALIAN MITOCHONDRIAL RIBOSOME, PART 2 OF 2 | RIBOSOME, TRANSLATION, LARGE RIBOSOMAL SUBUNIT, MITORIBOSOME, MAMMALIAN MITOCHONDRIAL RIBOSOME, CRYO-EM
3qpj:B (ASN83) to (GLY94) HIV-1 PROTEASE (MUTANT Q7K L33I L63I) IN COMPLEX WITH A THREE-ARMED PYRROLIDINE-BASED INHIBITOR | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3qrm:B (ASN83) to (GLY94) HIV-1 PROTEASE (MUTANT Q7K L33I L63I) IN COMPLEX WITH A THREE-ARMED PYRROLIDINE-BASED INHIBITOR | ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3qrv:A (ASP118) to (ASN144) CRYSTAL STRUCTURE OF PLASMEPSIN I (PMI) FROM PLASMODIUM FALCIPARUM | ASPARTIC PROTEASE, MALARIA, HYDROLASE
3quj:C (PRO245) to (GLN267) CRYSTAL STRUCTURE OF THE PHOSPHONATE BINDING PROTEIN, PHND, FROM ESCHERICHIA COLI | BIND AND TRANSPORT OF PHOSPHONATES, TRANSPORT PROTEIN
4fg9:A (GLY111) to (GLY136) CRYSTAL STRUCTURE OF HUMAN CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE I 1-320 IN COMPLEX WITH ATP | CAMK, CALMODULIN, AUTOINHIBITION, REGULATION MECHANISM, KINASE, TRANSFERASE
4fgc:B (LEU30) to (ARG40) CRYSTAL STRUCTURE OF ACTIVE SITE MUTANT C55A OF NITRILE REDUCTASE QUEF, BOUND TO SUBSTRATE PREQ0 | BETA BARREL, PTERIN BINDING FOLD, TUNNEL FOLD, TRNA MODIFICATION ENZYME, 7-CYANO-7-DEAZAGUANINE (PREQ0) BINDING, NADPH BINDING, OXIDOREDUCTASE
3qwp:A (GLY194) to (ASN205) CRYSTAL STRUCTURE OF SET AND MYND DOMAIN CONTAINING 3; ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 1 | SMYD3,SET AND MYND DOMAIN, ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 1, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
3r04:A (PRO125) to (GLU135) THE DISCOVERY OF NOVEL BENZOFURAN-2-CARBOXYLIC ACIDS AS POTENT PIM-1 INHIBITORS | KINAE, PIM1, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3r2i:A (GLU161) to (ARG181) CRYSTAL STRUCTURE OF SUPERANTIGEN-LIKE PROTEIN, EXOTOXIN SACOL0473 FROM STAPHYLOCOCCUS AUREUS SUBSP. AUREUS COL | STRUCTURAL GENOMICS, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, SUPERANTIGEN-LIKE PROTEIN, EXTRACELLULAR REGION, UNKNOWN FUNCTION
3r4b:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH TMC310911 | DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3r4t:A (SER7) to (ALA29) CRYSTAL STRUCTURE OF 4-AMINOBUTYRATE AMINOTRANSFERASE GABT FROM MYCOBACTERIUM MARINUM COVALENTLY BOUND TO PYRIDOXAL PHOSPHATE | STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, MYCOBACTERIUM, TUBERCULOSIS, SMEGMATIS, MARINUM, WATER CONTAMINANT, PYRIDOXAL PHOSPHATE, PLP, LLP, GAMMA AMINO BUTYRIC ACID, GABA, GABA TRANSFERASE, GABACULINE, PHENELZINE, AMINOOXYACETIC ACID, PHENYLETHYLIDENEHYDRAZINE, VIGABATRIN, VALPROIC ACID, TRANSFERASE
3r5a:D (PRO88) to (ARG116) PSEUDOMONAS AERUGINOSA DAPD (PA3666) IN COMPLEX WITH D-2-AMINOPIMELATE | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3r5b:A (PRO88) to (ARG116) PSEUDOMONAS AERUGINOSA DAPD (PA3666) IN COMPLEX WITH L-2-AMINOPIMELATE | TRANSFERASE-TRANSFERASE SUBSTRATE COMPLEX
3r5c:A (PRO88) to (ARG116) PSEUDOMONAS AERUGINOSA DAPD (PA3666) IN COMPLEX WITH COA AND SUCCINATE | TRANSFERASE
4fl8:B (ASN83) to (GLY94) HIV-1 PROTEASE COMPLEXED WITH GEM-DIOL-AMINE TETRAHEDRAL INTERMEDIATE | HYDROLASE, CATALYTIC MECHANISM, DRUG RESISTANCE, ASPARTIC PROTEASE
4flg:A (ASN83) to (GLY94) HIV-1 PROTEASE MUTANT I47V COMPLEXED WITH REACTION INTERMEDIATE | HYDROLASE, CATALYTIC MECHANISM, DRUG RESISTANCE, ASPARTIC PROTEASE
4flr:A (ASN186) to (GLY201) CRYSTAL STRUCTURE OF AMYLOSUCRASE DOUBLE MUTANT A289P-F290L FROM NEISSERIA POLYSACCHAREA | BETA/ALPHA-BARREL, GLYCOSIDE HYDROLASE, AMYLOSE SYNTHESIS, SUCROSE ISOMERIZATION, GLUCOSYLTRANSFERASE, CARBOHYDRATE, TRANSFERASE
4w8f:A (ARG3514) to (GLU3536) CRYSTAL STRUCTURE OF THE DYNEIN MOTOR DOMAIN IN THE AMPPNP-BOUND STATE | CYTOPLASMIC DYNEIN, MICROTUBULE, ATPASE, AAA+, AMPPNP
5ja2:A (ILE224) to (LEU243) ENTF, A TERMINAL NONRIBOSOMAL PEPTIDE SYNTHETASE MODULE BOUND TO THE NON-NATIVE MBTH-LIKE PROTEIN PA2412 | NONRIBOSOMAL PEPTIDE SYNTHETASE, NRPS, CONDENSATION, ADENYLATION, PCP, THIOESTERASE, MBTH-LIKE PROTEIN, PHOSPHOPANTETHEINE, BIOSYNTHETIC PROTEIN, LIGASE
4fm6:A (ASN83) to (GLY94) HIV-1 PROTEASE MUTANT V32I COMPLEXED WITH REACTION INTERMEDIATE | HYDROLASE, CATALYTIC MECHANISM, DRUG RESISTANCE, ASPARTIC PROTEASE
3r7f:A (ILE115) to (PHE142) CRYSTAL STRUCTURE OF CP-BOUND ASPARTATE TRANSCARBAMOYLASE FROM BACILLUS SUBTILIS | ASPARTATE TRANSCARBAMOYLASE, CARBAMOYL PHOSPHATE, TRANSFERASE, CATALYTIC CYCLE
3ram:A (GLY280) to (GLY302) CRYSTAL STRUCTURE OF HMRA | TWO-DOMAIN, CATALYTIC (ALPHA-BETA-ALPHA) MOTIF, TETRAMERISATION (ALPHA,BETA,BETA,ALPHA), ENDOPROTEASE, HYDROLASE
3ram:D (ASN279) to (GLY302) CRYSTAL STRUCTURE OF HMRA | TWO-DOMAIN, CATALYTIC (ALPHA-BETA-ALPHA) MOTIF, TETRAMERISATION (ALPHA,BETA,BETA,ALPHA), ENDOPROTEASE, HYDROLASE
5jfp:B (ASN83) to (GLY94) HIV-1 WILD TYPE PROTEASE WITH GRL-097-13A (A ADAMANTANE P1-LIGAND WITH BIS-THF IN P2 AND ISOBUTYLAMINE IN P1') | ADAMANTANE, HIV-1 PROTEASE INHIBITOR GRL-097-13A, DARUNAVIR, MULTIDRUG-RESISTANT, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5jfu:B (ASN83) to (GLY94) HIV-1 WILD TYPE PROTEASE WITH GRL-007-14A (A ADAMANTANE P1-LIGAND WITH BIS-THF IN P2 AND BENZYLAMINE IN P1') | ADAMANTANE, HIV-1 PROTEASE INHIBITOR GRL-007-14A, DARUNAVIR, MULTIDRUG-RESISTANT, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3rbw:A (ASP38) to (TYR49) CRYSTAL STRUCTURE OF SPIRE KIND DOMAIN | C-LOBE OF PROTEIN KINASES, ACTIN NUCLEATOR, FMN-FAMILY FORMINS, PROTEIN BINDING
3rbw:B (ASP38) to (TYR49) CRYSTAL STRUCTURE OF SPIRE KIND DOMAIN | C-LOBE OF PROTEIN KINASES, ACTIN NUCLEATOR, FMN-FAMILY FORMINS, PROTEIN BINDING
5jhs:F (HIS224) to (ASN244) YEAST 20S PROTEASOME IN COMPLEX WITH THE PEPTIDIC EPOXYKETONE INHIBITOR 15 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, INHIBITOR, BINDING ANALYSIS
5jhs:T (HIS224) to (ASN244) YEAST 20S PROTEASOME IN COMPLEX WITH THE PEPTIDIC EPOXYKETONE INHIBITOR 15 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, INHIBITOR, BINDING ANALYSIS
5ji2:F (ASN417) to (HIS428) HSLU L199Q IN HSLUV COMPLEX | AAA+ ATPASE, PEPTIDASE, HYDROLASE
4fwt:A (VAL268) to (SER286) COMPLEX STRUCTURE OF VIRAL RNA POLYMERASE FORM III | RNA POLYMERASE, TRANSLATION, TRANSFERASE-RNA COMPLEX
5jtw:A (LEU85) to (GLY98) CRYSTAL STRUCTURE OF COMPLEMENT C4B RE-REFINED USING IMDFF | INNATE IMMUNE SYSTEM, COMPLEMENT, ACTIVE FORM, IMMUNE SYSTEM
4fyv:A (VAL122) to (ILE145) ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH DCTP | ALLOSTERIC REGULATION, ASPARTATE CARBAMOYLTRANSFERASE, ESCHERICHIA COLI, TRANSFERASE
4fyx:C (VAL122) to (ILE145) E. COLI ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH DCTP, UTP, AND MG2+ | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, ALLOSTERY, TRANSFERASE
4fyy:A (VAL122) to (ILE145) E. COLI ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH CTP, UTP, AND MG2+ | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, ALLOSTERY, TRANSFERASE
4g11:A (TYR757) to (LEU774) X-RAY STRUCTURE OF PI3K-GAMMA BOUND TO A 4-(MORPHOLIN-4-YL)- (6-OXO-1, 6-DIHYDROPYRIMIDIN-2-YL)AMIDE INHIBITOR | PHOSPHOINOSITIDE 3-KINASE GAMMA, SECONDARY MESSENGER GENERATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4g6i:A (ASP181) to (GLN199) CRYSTALLOGRAPHIC STRUCTURE OF TRIMERIC RIBOFLAVIN SYNTHASE FROM BRUCELLA ABORTUS IN COMPLEX WITH ROSEOFLAVIN | TRANSFERASE, BETA BARREL, ALPHA + BETA PROTEIN, RIBOFLAVIN BIOSYNTHESIS
5k25:C (GLY433) to (ARG446) CRYSTAL STRUCTURE OF HUMAN PHOSPHATASE PRL-2 IN COMPLEX WITH THE ADP- BOUND BATEMAN DOMAIN OF HUMAN MAGNESIUM TRANSPORTER CNNM3 | COMPLEX, PHOSPHATASE, MAGNESIUM TRANSPORTER, PROTEIN BINDING, HYDROLASE, HYDROLASE-TRANSPORTER PROTEIN-PROTEIN BINDING COMPLEX
5k8o:B (PHE331) to (GLY358) MN2+/5NSA-BOUND 5-NITROANTHRANILATE AMINOHYDROLASE | NITROAROMATICS, DEAMINASE, METALLOENZYME, HYDROLASE
5k8p:C (PHE331) to (GLY358) ZN2+/TETRAHEDRAL INTERMEDIATE-BOUND R289A 5-NITROANTHRANILATE AMINOHYDROLASE | NITROAROMATICS, DEAMINASE, METALLOENZYME, HYDROLASE
5k8p:E (PHE331) to (GLY358) ZN2+/TETRAHEDRAL INTERMEDIATE-BOUND R289A 5-NITROANTHRANILATE AMINOHYDROLASE | NITROAROMATICS, DEAMINASE, METALLOENZYME, HYDROLASE
5k8p:G (PHE331) to (VAL356) ZN2+/TETRAHEDRAL INTERMEDIATE-BOUND R289A 5-NITROANTHRANILATE AMINOHYDROLASE | NITROAROMATICS, DEAMINASE, METALLOENZYME, HYDROLASE
5kbq:A (SER419) to (ARG438) PAK1 IN COMPLEX WITH BIS-ANILINO PYRIMIDINE INHIBITOR | SERINE/THREONINE-PROTEIN KINASE PAK1, KINASE, TRANSFERASE
4gb2:A (ASN83) to (GLY94) HIV-1 PROTEASE (MUTANT Q7K L33I L63I) IN COMPLEX WITH A BICYCLIC PYRROLIDINE INHIBITOR | DIMER, ASPARTYL PROTEASE, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4gdn:C (THR90) to (GLY113) STRUCTURE OF FMTA-LIKE PROTEIN | PEPTIDASE, ALPHA/BETA, HYDROLASE
5kem:B (GLY55) to (ARG64) EBOV SGP IN COMPLEX WITH VARIABLE FAB DOMAINS OF IGGS C13C6 AND BDBV91 | EBOLA VIRUS SECRETED GLYCOPROTEIN, SGP, ANTIBODIES, VIRAL PROTEIN- IMMUNE SYSTEM COMPLEX
5kem:G (GLY55) to (ARG64) EBOV SGP IN COMPLEX WITH VARIABLE FAB DOMAINS OF IGGS C13C6 AND BDBV91 | EBOLA VIRUS SECRETED GLYCOPROTEIN, SGP, ANTIBODIES, VIRAL PROTEIN- IMMUNE SYSTEM COMPLEX
4gi7:D (TYR1012) to (ASP1025) CRYSTAL STRUCTURE OF KLEBSIELLA PNEUMONIAE PANTOTHENATE KINASE IN COMPLEX WITH A PANTOTHENATE ANALOGUE | PROTEIN-SUBSTRATE COMPLEX, TRANSFERASE
5kit:B (THR468) to (ALA480) CRYSTAL STRUCTURE OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) IN COMPLEX WITH INHIBITORS 37 | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4gmz:A (MET173) to (GLY185) STRUCTURE OF RAT CYTOSOLIC PEPCK LD_2G IN COMPLEX WITH BETA- SULFOPYRUVATE AND GTP | KINASE, GLUCONEOGENESIS, LYASE
4go2:B (CYS451) to (PHE472) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE IN COMPLEX WITH THIO-NADP | ALDEHYDE DEHYDROGENASE, FDH, OXIDOREDUCTASE
4go2:D (CYS451) to (PHE472) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE IN COMPLEX WITH THIO-NADP | ALDEHYDE DEHYDROGENASE, FDH, OXIDOREDUCTASE
5koh:B (MET145) to (GLY158) NITROGENASE MOFEP FROM GLUCONACETOBACTER DIAZOTROPHICUS IN DITHIONITE REDUCED STATE | NITROGENASE, ELECTRON TRANSFER, OXIDOREDUCTASE, P-CLUSTER
5koh:D (MET145) to (GLY158) NITROGENASE MOFEP FROM GLUCONACETOBACTER DIAZOTROPHICUS IN DITHIONITE REDUCED STATE | NITROGENASE, ELECTRON TRANSFER, OXIDOREDUCTASE, P-CLUSTER
5koj:B (MET145) to (GLY158) NITROGENASE MOFEP PROTEIN IN THE IDS OXIDIZED STATE | NITROGENASE, ELECTRON TRANSFER, OXIDOREDUCTASE, P-CLUSTER
5koj:D (MET145) to (GLY158) NITROGENASE MOFEP PROTEIN IN THE IDS OXIDIZED STATE | NITROGENASE, ELECTRON TRANSFER, OXIDOREDUCTASE, P-CLUSTER
5kqx:B (ASN83) to (GLY94) PROTEASE E35D-SQV | HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE-HUDROLASE INHIBITOR COMPLEX
5kr0:B (ASN83) to (GLY94) PROTEASE E35D-APV | HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5kr1:B (ASN83) to (GLY94) PROTEASE PR5-DRV | HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5kzh:D (SER73) to (HIS94) HIGH RESOLUTION STRUCTURE OF ACINETOBACTER BAUMANNII BETA-LACTAMASE OXA-51 | HYDROLASE, ANTIBIOTIC
5l46:A (GLN269) to (LEU284) CRYSTAL STRUCTURE OF HUMAN DIMETHYLGLYCINE-DEHYDROGENASE | ELECTRON TRANSFER, COVALENT FLAVINYLATION, OXIDOREDUCTASE, ONE-CARBON METABOLISM
5l54:F (HIS224) to (ASN244) YEAST 20S PROTEASOME IN COMPLEX WITH EPOXYKETONE INHIBITOR 16 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, INHIBITOR, BINDING ANALYSIS
5l54:T (HIS224) to (ASN244) YEAST 20S PROTEASOME IN COMPLEX WITH EPOXYKETONE INHIBITOR 16 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, INHIBITOR, BINDING ANALYSIS
5lf7:Q (SER216) to (GLU240) HUMAN 20S PROTEASOME COMPLEX WITH IXAZOMIB AT 2.0 ANSTROM | PROTEASOME, MULTICATALYTIC PROTEINASE, NTN-HYDROLASE, HYDROLASE
5sx4:L (THR109) to (GLY128) CRYSTAL STRUCTURE OF PANITUMUMAB IN COMPLEX WITH EPIDERMAL GROWTH FACTOR RECEPTOR DOMAIN 3. | CETUXIMAB, PANITUMUMAB, EGFR, VECTIBIX, ERBITUX, TRANSFERASE-IMMUNE SYSTEM COMPLEX
5t0i:c (ALA28) to (VAL49) STRUCTURAL BASIS FOR DYNAMIC REGULATION OF THE HUMAN 26S PROTEASOME | UBIQUITIN-PROTEASOME SYSTEM, AAA-ATPASE, HYDROLASE
5t0j:a (ARG289) to (ALA300) STRUCTURAL BASIS FOR DYNAMIC REGULATION OF THE HUMAN 26S PROTEASOME | UBIQUITIN-PROTEASOME SYSTEM, AAA-ATPASE, HYDROLASE
5t0v:C (GLY155) to (LYS172) ARCHITECTURE OF THE YEAST MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY MACHINERY: THE SUB-COMPLEX FORMED BY THE IRON DONOR, YFH1, AND THE SCAFFOLD, ISU1 | FRIEDREICH ATAXIA, FRATAXIN, IRON-SULFUR PROTEIN, MITOCHONDRIA, PROTEIN COMPLEX, OXIDOREDUCTASE
7at1:A (VAL122) to (THR148) CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H | TRANSFERASE (CARBAMOYL-P,ASPARTATE)
7at1:C (VAL122) to (THR148) CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H | TRANSFERASE (CARBAMOYL-P,ASPARTATE)
8atc:C (VAL122) to (THR148) COMPLEX OF N-PHOSPHONACETYL-L-ASPARTATE WITH ASPARTATE CARBAMOYLTRANSFERASE. X-RAY REFINEMENT, ANALYSIS OF CONFORMATIONAL CHANGES AND CATALYTIC AND ALLOSTERIC MECHANISMS | TRANSFERASE (CARBAMOYL-P,ASPARTATE)
8hvp:B (ASN83) to (GLY94) STRUCTURE AT 2.5-ANGSTROMS RESOLUTION OF CHEMICALLY SYNTHESIZED HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE COMPLEXED WITH A HYDROXYETHYLENE*-BASED INHIBITOR | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
9atc:A (VAL122) to (GLY150) ATCASE Y165F MUTANT | ATCASE, ALLOSTERY, PYRIMIDINE BIOSYNTHESIS, TRANSFERASE
2oib:A (HIS166) to (THR177) CRYSTAL STRUCTURE OF IRAK4 KINASE DOMAIN APO FORM | KINASE, HELIC C, TRANSFERASE
4wi6:B (GLN342) to (ASN361) STRUCTURAL MAPPING OF THE HUMAN IGG1 BINDING SITE FOR FCRN: HU3S193 FC MUTATION N434A | HUMAN IGG1, FCRN BINDING SITE, THERAPEUTIC ANTIBODY, IMMUNE SYSTEM
2avs:A (ASN83) to (GLY94) KINETICS, STABILITY, AND STRUCTURAL CHANGES IN HIGH RESOLUTION CRYSTAL STRUCTURES OF HIV-1 PROTEASE WITH DRUG RESISTANT MUTATIONS L24I, I50V, AND G73S | DRUG RESISTANCE, HIV-1 PROTEASE,INDINAVIR, SUBSTRATE ANALOG, NON-ACTIVE SITE MUTANTS., HYDROLASE
2avs:B (ASN83) to (GLY94) KINETICS, STABILITY, AND STRUCTURAL CHANGES IN HIGH RESOLUTION CRYSTAL STRUCTURES OF HIV-1 PROTEASE WITH DRUG RESISTANT MUTATIONS L24I, I50V, AND G73S | DRUG RESISTANCE, HIV-1 PROTEASE,INDINAVIR, SUBSTRATE ANALOG, NON-ACTIVE SITE MUTANTS., HYDROLASE
2azc:A (ASN83) to (GLY94) HIV-1 PROTEASE NL4-3 6X MUTANT | HIV, PROTEASE, INHIBITOR, TL-3, 6X, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4wn9:D (ALA20) to (LEU33) STRUCTURE OF THE NITROGENASE MOFE PROTEIN FROM CLOSTRIDIUM PASTEURIANUM PRESSURIZED WITH XENON | XENON, MOFE PROTEIN, NITROGENASE, OXIDOREDUCTASE
1amo:A (HIS601) to (ARG613) THREE-DIMENSIONAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE: PROTOTYPE FOR FMN-AND FAD-CONTAINING ENZYMES | X-RAY CRYSTALLOGRAPHY, FLAVOPROTEIN, NITRIC OXIDE SYNTHASE, OXIDOREDUCTASE
1amo:B (HIS601) to (ARG613) THREE-DIMENSIONAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE: PROTOTYPE FOR FMN-AND FAD-CONTAINING ENZYMES | X-RAY CRYSTALLOGRAPHY, FLAVOPROTEIN, NITRIC OXIDE SYNTHASE, OXIDOREDUCTASE
3ekx:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF THE WILD-TYPE HIV-1 PROTEASE WITH THE INHIBITOR, NELFINAVIR | HIV PROTEASE, PROTEASE INHIBITORS, DRUG RESISTANCE, AMPRENAVIR, AIDS, PROTEASE, HYDROLASE
1nul:B (TYR5) to (MET24) XPRTASE FROM E. COLI | PHOSPHORIBOSYLTRANSFERASE, TRANSFERASE, PURINE SALVAGE ENZYME
2b7n:B (ALA154) to (VAL165) CRYSTAL STRUCTURE OF QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE FROM HELICOBACTER PYLORI | QUINOLINATE PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, HELICOBACTER PYLORI, TRANSFERASE
4wt6:A (PRO125) to (ARG136) CRYSTAL STRUCTURE OF HUMAN PIM-1 KINASE IN COMPLEX WITH A THIADIAZOLAMINE-INDOLE INHIBITOR. | TRANSFERASE, SERINE/THREONINE PROTEIN KINASE
1nww:A (PHE134) to (VAL143) LIMONENE-1,2-EPOXIDE HYDROLASE | EPOXIDE HYDROLASE
1nww:B (PHE134) to (VAL143) LIMONENE-1,2-EPOXIDE HYDROLASE | EPOXIDE HYDROLASE
2b9u:C (VAL30) to (ARG40) CRYSTAL STRUCTURE OF DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE FROM SULFOLOBUS TOKODAII | BETA CLASS, JELLY ROLL-LIKE TOPOLOGY, FLATTENED BARREL, ISOMERASE
2b9u:D (VAL30) to (ARG40) CRYSTAL STRUCTURE OF DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE FROM SULFOLOBUS TOKODAII | BETA CLASS, JELLY ROLL-LIKE TOPOLOGY, FLATTENED BARREL, ISOMERASE
2b9u:B (VAL30) to (ARG40) CRYSTAL STRUCTURE OF DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE FROM SULFOLOBUS TOKODAII | BETA CLASS, JELLY ROLL-LIKE TOPOLOGY, FLATTENED BARREL, ISOMERASE
2b9u:F (VAL30) to (ARG40) CRYSTAL STRUCTURE OF DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE FROM SULFOLOBUS TOKODAII | BETA CLASS, JELLY ROLL-LIKE TOPOLOGY, FLATTENED BARREL, ISOMERASE
2b9u:H (VAL30) to (ARG40) CRYSTAL STRUCTURE OF DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE FROM SULFOLOBUS TOKODAII | BETA CLASS, JELLY ROLL-LIKE TOPOLOGY, FLATTENED BARREL, ISOMERASE
4hbc:L (THR116) to (THR129) CRYSTAL STRUCTURE OF A CONFORMATION-DEPENDENT RABBIT IGG FAB SPECIFIC FOR AMYLOID PREFIBRILLAR OLIGOMERS | FAB, RABBIT, CONFORMATION-SPECIFIC, AMYLOID, IMMUNE SYSTEM
1bdr:B (ASN83) to (GLY94) HIV-1 (2: 31, 33-37) PROTEASE COMPLEXED WITH INHIBITOR SB203386 | HYDROLASE, AIDS, POLYPROTEIN, ASPARTYL PROTEASE, ACID PROTEASE, HYDROXYETHYLENE ISOSTERE INHIBITOR, SUBSTRATE ANALOGUE INHIBITOR
4hio:A (TYR116) to (TYR140) CRYSTAL STRUCTURE OF SCHIZOSACCHAROMYCES POMBE POT1PC BOUND TO SSDNA (GGTAACGGT) | SPECIFICITY, PLASTICITY, PROMISCUITY, OB-FOLD, SSDNA-BINDING, SINGLE- STRANDED TELOMERIC DNA, DNA BINDING PROTEIN
4x3l:B (MET1) to (GLU19) CRYSTAL STRUCTURE OF TTHA0275 FROM THERMUS THERMOPHILUS (HB8) IN COMPLEX WITH 5'-METHYLTHIOADENOSINE IN SPACE GROUP P21212 | TTHA0275 METHYLTRANSFERASE ADOMET 5'-METHYLTHIOADENOSINE, TRANSFERASE
4x3m:A (MET1) to (GLU19) CRYSTAL STRUCTURE OF TTHA0275 FROM THERMUS THERMOPHILUS (HB8) IN COMPLEX WITH ADENOSINE IN SPACE GROUP P212121 | TTHA0275 METHYLTRANSFERASE ADOMET ADENOSINE, TRANSFERASE
4x3m:B (MET1) to (GLU19) CRYSTAL STRUCTURE OF TTHA0275 FROM THERMUS THERMOPHILUS (HB8) IN COMPLEX WITH ADENOSINE IN SPACE GROUP P212121 | TTHA0275 METHYLTRANSFERASE ADOMET ADENOSINE, TRANSFERASE
3s53:A (ASN83) to (GLY94) HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH ANTIVIRAL DRUG DARUNAVIR IN SPACE GROUP P212121 | DARUNAVIR,HIV/AIDS, DRUG RESISTANCE, ASPARTIC PROTEASE, MOLECULAR RECOGNITION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1o93:A (PHE19) to (ASP50) METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH ATP AND A L-METHIONINE ANALOGOUS | TRANSFERASE, ADENOSYLTRANSFERASE, METHIONINE AND ATP BINDING
1o93:B (PHE19) to (ASP50) METHIONINE ADENOSYLTRANSFERASE COMPLEXED WITH ATP AND A L-METHIONINE ANALOGOUS | TRANSFERASE, ADENOSYLTRANSFERASE, METHIONINE AND ATP BINDING
1bwa:B (ASN83) to (GLY94) HIV-1 PROTEASE (V82F/I84V) DOUBLE MUTANT COMPLEXED WITH XV638 OF DUPONT PHARMACEUTICALS | HIV-1 PROTEASE, HYDROLASE
4xgr:G (MSE0) to (ASP14) CRYSTAL STRUCTURE OF ADDICTION MODULE FROM MYCOBACTERIAL SPECIES | MYCOBACTERIA, ADDICTION MODULE, TOXIN-ANTITOXIN COMPLEX
4xgr:E (MSE0) to (LEU12) CRYSTAL STRUCTURE OF ADDICTION MODULE FROM MYCOBACTERIAL SPECIES | MYCOBACTERIA, ADDICTION MODULE, TOXIN-ANTITOXIN COMPLEX
4xgr:C (MSE0) to (ASP14) CRYSTAL STRUCTURE OF ADDICTION MODULE FROM MYCOBACTERIAL SPECIES | MYCOBACTERIA, ADDICTION MODULE, TOXIN-ANTITOXIN COMPLEX
4i9a:B (LEU167) to (GLY179) CRYSTAL STRUCTURE OF SUS SCROFA QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH NICOTINATE MONONUCLEOTIDE | TRANSFERASE
3sqf:A (VAL90) to (MET101) CRYSTAL STRUCTURE OF MONOMERIC M-PMV RETROVIRAL PROTEASE | FOLDED MONOMER, RETROVIRAL PROTEASE FOLDED AS A MONOMER, HYDROLASE, ASPARTIC PROTEASE, RETROVIRAL PROTEASE, RETROPEPSIN, D-TYPE RETROVIRUS
3sqf:B (VAL90) to (MET101) CRYSTAL STRUCTURE OF MONOMERIC M-PMV RETROVIRAL PROTEASE | FOLDED MONOMER, RETROVIRAL PROTEASE FOLDED AS A MONOMER, HYDROLASE, ASPARTIC PROTEASE, RETROVIRAL PROTEASE, RETROPEPSIN, D-TYPE RETROVIRUS
2c7d:D (ILE493) to (THR517) FITTED COORDINATES FOR GROEL-ADP7-GROES CRYO-EM COMPLEX (EMD-1181) | ATP-BINDING, CHAPERONE, ATOMIC STRUCTURE FITTING, CELL CYCLE, CELL DIVISION, CHAPERONIN, NUCLEOTIDE-BINDING, PHOSPHORYLATION
2c7d:M (ILE493) to (THR517) FITTED COORDINATES FOR GROEL-ADP7-GROES CRYO-EM COMPLEX (EMD-1181) | ATP-BINDING, CHAPERONE, ATOMIC STRUCTURE FITTING, CELL CYCLE, CELL DIVISION, CHAPERONIN, NUCLEOTIDE-BINDING, PHOSPHORYLATION
2c7d:N (ILE493) to (THR517) FITTED COORDINATES FOR GROEL-ADP7-GROES CRYO-EM COMPLEX (EMD-1181) | ATP-BINDING, CHAPERONE, ATOMIC STRUCTURE FITTING, CELL CYCLE, CELL DIVISION, CHAPERONIN, NUCLEOTIDE-BINDING, PHOSPHORYLATION
3st5:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE WITH C3-SUBSTITUTED HEXAHYDROCYCLOPENTAFURANYL URETHANE AS P2-LIGAND, GRL-0489A | ASPARTIC ACID PROTEASE, HIV-1 PROTEASE INHIBITOR GRL-0489A, C3- SUBSTITUTED HEXAHYDROCYCLOPENTAFURANYL URETHANE AS P2-LIGANDS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1cyx:A (PRO242) to (ALA256) QUINOL OXIDASE (PERIPLASMIC FRAGMENT OF SUBUNIT II WITH ENGINEERED CU-A BINDING SITE)(CYOA) | ELECTRON TRANSPORT
1d09:C (PRO123) to (THR148) ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH N-PHOSPHONACETYL-L- ASPARTATE (PALA) | PROTEIN-INHIBITOR COMPLEX ASPARTATE TRANSCARBAMOYLASE ASPARTATE TRANSCARBAMYLASE, TRANSFERASE
2cen:A (ASN83) to (GLY94) P1' EXTENDED HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMICKING SCAFFOLD | HIV-1, PROTEASE, INHIBITOR, ASPARTYL PROTEASE, HYDROLASE
2cen:B (ASN183) to (GLY194) P1' EXTENDED HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMICKING SCAFFOLD | HIV-1, PROTEASE, INHIBITOR, ASPARTYL PROTEASE, HYDROLASE
1d4s:B (ASN83) to (GLY94) HIV-1 PROTEASE V82F/I84V DOUBLE MUTANT/TIPRANAVIR COMPLEX | HYDROLASE, ACID PROTEASE, ASPARTYL PROTEASE
4ist:B (ILE45) to (SER62) S177A KLUYVEROMYCES LACTIS ALLOPHANATE HYDROLASE | MIXED ALPHA AND BETA STRUCTURE, ALLOPHANATE BINDING, HYDROLASE
3ggx:A (ASN83) to (GLY94) HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS | HIV PROTEASE, PSEUDO-SYMMETRIC INHIBITORS, HYDROLASE, PROTEASE
3git:D (ASN426) to (GLY438) CRYSTAL STRUCTURE OF A TRUNCATED ACETYL-COA SYNTHASE | ACETYLTRANSFERASE, CARBON DIOXIDE FIXATION, IRON, IRON-SULFUR, METAL- BINDING, NICKEL, TRANSFERASE
4y7c:A (HIS601) to (ARG613) RAT CYPOR MUTANT - G141DEL/E142N | CYTOCHROME P450 REDUCTASE, FMN BINDING, SEMIQUINONE, OXIDOREDUCTASE
4y7c:B (HIS601) to (ASP612) RAT CYPOR MUTANT - G141DEL/E142N | CYTOCHROME P450 REDUCTASE, FMN BINDING, SEMIQUINONE, OXIDOREDUCTASE
2r6o:A (HIS664) to (ILE676) CRYSTAL STRUCTURE OF PUTATIVE DIGUANYLATE CYCLASE/PHOSPHODIESTERASE FROM THIOBACILLUS DENITRIFICANS | DIGUANYLATE CYCLASE, GGDEF AND EAL DOMAINS, THIOBACILLUS DENITRIFICANS, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, TRANSFERASE, UNKNOWN FUNCTION
4y8k:F (HIS224) to (ASN244) YEAST 20S PROTEASOME IN COMPLEX WITH H-APLL-EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, INHIBITOR, BINDING ANALYSIS
4y8k:T (HIS224) to (ASN244) YEAST 20S PROTEASOME IN COMPLEX WITH H-APLL-EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, INHIBITOR, BINDING ANALYSIS
4y8p:F (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA7-DELTA7_CTER MUTANT IN COMPLEX WITH AC-PAL- EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
4y8p:T (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA7-DELTA7_CTER MUTANT IN COMPLEX WITH AC-PAL- EP | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
1ebz:B (ASN183) to (GLY194) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA388 | DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
1ec2:B (ASN183) to (GLY194) HIV-1 PROTEASE IN COMPLEX WITH THE INHIBITOR BEA428 | DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
4y9r:A (HIS601) to (ARG613) RAT CYPOR MUTANT - G141DEL | CYTOCHROME P450 REDUCTASE, FMN BINDING, SEMIQUINONE, OXIDOREDUCTASE
4y9r:B (HIS601) to (ARG613) RAT CYPOR MUTANT - G141DEL | CYTOCHROME P450 REDUCTASE, FMN BINDING, SEMIQUINONE, OXIDOREDUCTASE
1ekx:A (VAL122) to (THR148) THE ISOLATED, UNREGULATED CATALYTIC TRIMER OF ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH BISUBSTRATE ANALOG PALA (N-(PHOSPHONACETYL)-L-ASPARTATE) | ATCASE CATALYTIC SUBUNIT, BISUBSTRATE ANALOG COMPLEX, TRANSFERASE
1ekx:C (VAL122) to (THR148) THE ISOLATED, UNREGULATED CATALYTIC TRIMER OF ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH BISUBSTRATE ANALOG PALA (N-(PHOSPHONACETYL)-L-ASPARTATE) | ATCASE CATALYTIC SUBUNIT, BISUBSTRATE ANALOG COMPLEX, TRANSFERASE
3tto:A (ASP2445) to (GLU2460) CRYSTAL STRUCTURE OF LEUCONOSTOC MESENTEROIDES NRRL B-1299 N- TERMINALLY TRUNCATED DEXTRANSUCRASE DSR-E IN TRICLINIC FORM | (BETA/ALPHA)8 BARREL, SUCROSE/DEXTRAN/GLUCO-OLIGOSACCHARIDE BINDING, ALPHA-1,2 BRANCHING DEXTRANSUCRASE, TRANSFERASE
2e1r:A (GLY217) to (GLY234) STRUCTURE OF EEF2 IN COMPLEX WITH A SORDARIN DERIVATIVE | PROTEIN-LIGAND COMPLEX, G-PROTEIN, TRANSLATION
1f31:A (PHE1256) to (ARG1268) CRYSTAL STRUCTURE OF CLOSTRIDIUM BOTULINUM NEUROTOXIN B COMPLEXED WITH A TRISACCHARIDE | BOTULINUM, ZINC, METALLOPROTEASE, TRANSMEMBRANE, NEUROTOXIN, COMPLEX, GANGLIOSIDE
3h97:A (ASP92) to (GLY117) STRUCTURE OF A MUTANT METHIONYL-TRNA SYNTHETASE WITH MODIFIED SPECIFICITY | ROSSMANN FOLD, AMINOACYL-TRNA SYNTHETASE, ATP-BINDING, LIGASE, METAL- BINDING, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, RNA-BINDING, TRNA-BINDING
2eb6:A (GLY59) to (GLN74) CRYSTAL STRUCTURE OF HPCG COMPLEXED WITH MG ION | LYASE, HYDRATASE
1r3n:A (LEU359) to (GLN382) CRYSTAL STRUCTURE OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI | ALPHA AND BETA PROTEIN, DI-ZINC CENTER, HYDROLASE
1r3n:B (LEU359) to (GLN382) CRYSTAL STRUCTURE OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI | ALPHA AND BETA PROTEIN, DI-ZINC CENTER, HYDROLASE
1r3n:C (LEU359) to (GLN382) CRYSTAL STRUCTURE OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI | ALPHA AND BETA PROTEIN, DI-ZINC CENTER, HYDROLASE
1r3n:G (LEU359) to (GLN382) CRYSTAL STRUCTURE OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI | ALPHA AND BETA PROTEIN, DI-ZINC CENTER, HYDROLASE
1r3n:H (LEU359) to (GLN382) CRYSTAL STRUCTURE OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI | ALPHA AND BETA PROTEIN, DI-ZINC CENTER, HYDROLASE
1fg8:D (ASN183) to (GLY194) STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES | HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2eo0:B (ASN114) to (GLY125) CRYSTAL STRUCTURE OF HOLLIDAY JUNCTION RESOLVASE ST1444 | HOLLIDAY JUNCTION RESOLVASE, DNA BINDING PROTEIN, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
1raf:A (VAL122) to (GLY150) CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | TRANSFERASE
2v8d:B (LEU359) to (GLN382) CRYSTAL STRUCTURE OF MUTANT E159A OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI | HYDROLASE, DI-ZINC CENTER, AMIDOHYDROLASE
2f80:B (ASN83) to (GLY94) HIV-1 PROTEASE MUTANT D30N COMPLEXED WITH INHIBITOR TMC114 | PROTEIN-INHIBITOR COMPLEX, HYDROLASE
4kgx:A (VAL122) to (THR148) THE R STATE STRUCTURE OF E. COLI ATCASE WITH CTP BOUND | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, COMPETING PATHWAY PRODUCT ACTIVATION, ALLOSTERY, TRANSFERASE
4kh1:A (VAL122) to (THR148) THE R STATE STRUCTURE OF E. COLI ATCASE WITH CTP,UTP, AND MAGNESIUM BOUND | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, COMPETING PATHWAY PRODUCT ACTIVATION, ALLOSTERY, TRANSFERASE
4kh1:C (VAL122) to (THR148) THE R STATE STRUCTURE OF E. COLI ATCASE WITH CTP,UTP, AND MAGNESIUM BOUND | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, COMPETING PATHWAY PRODUCT ACTIVATION, ALLOSTERY, TRANSFERASE
1g8i:A (GLY78) to (GLY95) CRYSTAL STRUCTURE OF HUMAN FREQUENIN (NEURONAL CALCIUM SENSOR 1) | CALCIUM BINDING-PROTEIN, EF-HAND, CALCIUM ION, METAL BINDING PROTEIN
1ga6:A (GLY354) to (SER367) CRYSTAL STRUCTURE ANALYSIS OF PSCP (PSEUDOMONAS SERINE-CARBOXYL PROTEINASE) COMPLEXED WITH A FRAGMENT OF TYROSTATIN (THIS ENZYME RENAMED "SEDOLISIN" IN 2003) | SERINE-CARBOXYL PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2fjk:A (PRO43) to (GLY57) CRYSTAL STRUCTURE OF FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE IN THERMUS CALDOPHILUS | BETA-ALPHA-BARRELS, LYASE
1s6c:A (GLY67) to (PHE82) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN KCHIP1 AND KV4.2 N1-30 | EF-HAND, TRANSPORT PROTEIN
3hur:A (ALA220) to (GLY230) CRYSTAL STRUCTURE OF ALANINE RACEMASE FROM OENOCOCCUS OENI | STRUCTURAL GENOMICS, ISOMERASE, PYRIDOXAL PHOSPHATE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
4kn7:C (GLY266) to (ASP281) X-RAY CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH BENZOXAZINORIFAMYCIN-2C | TRANSCRIPTION, DNA, RNA, TRANSFERASE-ANTIBIOTIC COMPLEX
1gnm:B (ASN83) to (GLY94) HIV-1 PROTEASE MUTANT WITH VAL 82 REPLACED BY ASP (V82D) COMPLEXED WITH U89360E (INHIBITOR) | ASPARTIC PROTEASE, HIV, MUTANT, INHIBITOR, U-89360E, HYDROLASE (ACID PROTEASE)
1sgu:B (ASN83) to (GLY94) COMPARING THE ACCUMULATION OF ACTIVE SITE AND NON-ACTIVE SITE MUTATIONS IN THE HIV-1 PROTEASE | ACTIVE SITE MUTATIONS, NON-ACTIVE SITE MUTATIONS, INDINAVIR, HIV-1 PROTEASE, HYDROLASE
3i2l:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF A CHEMICALLY SYNTHESIZED [ALLO-ILE50/50']HIV-1 PROTEASE MOLECULE COMPLEXED WITH MVT-101 REDUCED ISOSTERE INHIBITOR | BETA-SHEET, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1sku:A (VAL122) to (GLY150) E. COLI ASPARTATE TRANSCARBAMYLASE 240'S LOOP MUTANT (K244N) | ALLOSTERIC ENZYME, LOOP MOVEMENTS, SMALL-ANGLE X-RAY SCATTERING, DOMAIN CLOSURE, ALLOSTERIC TRANSITION, INTERSUBUNIT INTERACTIONS, TRANSFERASE
3i7n:A (LYS244) to (SER256) CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDTC1 | DDB1, WDTC1, DCAF9, H-BOX MOTIF, CYTOPLASM, DNA DAMAGE, DNA REPAIR, DNA-BINDING, HOST-VIRUS INTERACTION, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, UBL CONJUGATION, UBL CONJUGATION PATHWAY, ALTERNATIVE SPLICING, TPR REPEAT, WD REPEAT
3veg:A (LEU61) to (VAL75) RHODOCOCCUS JOSTII RHA1 DYPB R244L VARIANT IN COMPLEX WITH HEME | PEROXIDASE, LIGNAN, DYP, OXIDOREDUCTASE
3veg:C (SER60) to (VAL75) RHODOCOCCUS JOSTII RHA1 DYPB R244L VARIANT IN COMPLEX WITH HEME | PEROXIDASE, LIGNAN, DYP, OXIDOREDUCTASE
1t15:A (PRO1831) to (TYR1845) CRYSTAL STRUCTURE OF THE BRCA1 BRCT DOMAINS IN COMPLEX WITH THE PHOSPHORYLATED INTERACTING REGION FROM BACH1 HELICASE | PROTEIN-PEPTIDE COMPLEX, ANTITUMOR PROTEIN
2gm1:A (ILE19) to (SER36) CRYSTAL STRUCTURE OF THE MITOTIC KINESIN EG5 IN COMPLEX WITH MG-ADP AND N-(3-AMINOPROPYL)-N-((3-BENZYL-5-CHLORO-4- OXO-3,4-DIHYDROPYRROLO[2,1-F][1,2,4]TRIAZIN-2-YL) (CYCLOPROPYL)METHYL)-4-METHYLBENZAMIDE | EG5 MG-ADP COMPLEX INHIBITOR, CELL CYCLE
2gm1:B (ILE19) to (SER36) CRYSTAL STRUCTURE OF THE MITOTIC KINESIN EG5 IN COMPLEX WITH MG-ADP AND N-(3-AMINOPROPYL)-N-((3-BENZYL-5-CHLORO-4- OXO-3,4-DIHYDROPYRROLO[2,1-F][1,2,4]TRIAZIN-2-YL) (CYCLOPROPYL)METHYL)-4-METHYLBENZAMIDE | EG5 MG-ADP COMPLEX INHIBITOR, CELL CYCLE
2gm1:D (ILE19) to (SER36) CRYSTAL STRUCTURE OF THE MITOTIC KINESIN EG5 IN COMPLEX WITH MG-ADP AND N-(3-AMINOPROPYL)-N-((3-BENZYL-5-CHLORO-4- OXO-3,4-DIHYDROPYRROLO[2,1-F][1,2,4]TRIAZIN-2-YL) (CYCLOPROPYL)METHYL)-4-METHYLBENZAMIDE | EG5 MG-ADP COMPLEX INHIBITOR, CELL CYCLE
2gm1:E (ILE19) to (SER36) CRYSTAL STRUCTURE OF THE MITOTIC KINESIN EG5 IN COMPLEX WITH MG-ADP AND N-(3-AMINOPROPYL)-N-((3-BENZYL-5-CHLORO-4- OXO-3,4-DIHYDROPYRROLO[2,1-F][1,2,4]TRIAZIN-2-YL) (CYCLOPROPYL)METHYL)-4-METHYLBENZAMIDE | EG5 MG-ADP COMPLEX INHIBITOR, CELL CYCLE
1h4q:A (THR228) to (PHE240) PROLYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH TRNAPRO(CGG), ATP AND PROLINOL | AMINOACYL-TRNA SYNTHETASE, ATP + L-PROLINE + TRNA(PRO) AMP + PPI + L-PROLYL-TRNA(PRO), CLASS II AMINOACYL-TRNA SYNTHETASE
1h56:B (HIS136) to (HIS152) STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF A NEW MAGNESIUM ION BINDING SITE NEAR TYR94 IN THE RESTRICTION ENDONUCLEASE PVUII | ENDONUCLEASE, TYPE II RESTRICTION ENDONUCLEASE, HYDROLASE, NUCLEASE,
1h7w:B (TYR762) to (ARG771) DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG | ELECTRON TRANSFER, FLAVIN, IRON-SULFUR CLUSTERS, PYRIMIDINE CATABOLISM, OXIDOREDUCTASE
1h7w:C (TYR762) to (ARG771) DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG | ELECTRON TRANSFER, FLAVIN, IRON-SULFUR CLUSTERS, PYRIMIDINE CATABOLISM, OXIDOREDUCTASE
2guf:A (PRO25) to (GLN38) IN MESO CRYSTAL STRUCTURE OF THE COBALAMIN TRANSPORTER, BTUB | BETA BARREL, CUBIC MESOPHASE, COBALAMIN, BTUB, COLICIN, TRANSPORT PROTEIN
1hiv:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF A COMPLEX OF HIV-1 PROTEASE WITH A DIHYDROETHYLENE-CONTAINING INHIBITOR: COMPARISONS WITH MOLECULAR MODELING | ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2wah:B (GLN342) to (ASN361) CRYSTAL STRUCTURE OF AN IGG1 FC GLYCOFORM (MAN9GLCNAC2) | IMMUNOGLOBULIN C REGION, ANTIBODY ENGINEERING, IMMUNOGLOBULIN DOMAIN, SECRETED, ANTIBODY, KIFUNENSINE, GLYCOPROTEIN, OLIGOMANNOSE, IMMUNE SYSTEM, GLYCOSYLATION
4lj7:C (ILE704) to (GLY722) CLPB NBD2 K601Q FROM T. THERMOPHILUS IN COMPLEX WITH MANT-DADP | AAA+ PROTEIN, NUCLEOTIDE BINDING DOMAIN, MOLECULAR CHAPERONE, DISAGGREGASE, CHAPERONE
3ix7:B (GLY142) to (GLY153) CRYSTAL STRUCTURE OF A DOMAIN OF FUNCTIONALLY UNKNOWN PROTEIN FROM THERMUS THERMOPHILUS HB8 | UNKNOWN FUNCTION, THERMUS THERMOPHILUS HB8, STRUCTURAL GENOMICS, PSI- 2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG
1hvl:A (ASN83) to (GLY94) INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEASE)
1hvl:B (ASN83) to (GLY94) INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE | HYDROLASE(ACID PROTEASE)
2wmc:A (SER58) to (GLN72) CRYSTAL STRUCTURE OF EUKARYOTIC INITIATION FACTOR 4E FROM PISUM SATIVUM | BIOSYNTHETIC PROTEIN, INITIATION FACTOR, PROTEIN BIOSYNTHESIS, EIF4E, SBM1 GENE, RNA-BINDING, PISUM SATIVUM
2wmc:C (SER58) to (LYS71) CRYSTAL STRUCTURE OF EUKARYOTIC INITIATION FACTOR 4E FROM PISUM SATIVUM | BIOSYNTHETIC PROTEIN, INITIATION FACTOR, PROTEIN BIOSYNTHESIS, EIF4E, SBM1 GENE, RNA-BINDING, PISUM SATIVUM
4ls4:B (LYS3) to (GLY21) CRYSTAL STRUCTURE OF L66S MUTANT TOXIN FROM HELICOBACTER PYLORI | TOXIN-ANTITOXIN SYSTEM, TOXIN
3vyr:B (VAL176) to (LYS189) CRYSTAL STRUCTURE OF THE HYPC-HYPD COMPLEX | [NIFE] HYDROGENASE MATURATION, METAL BINDING PROTEIN
3vyr:B (GLN195) to (ILE207) CRYSTAL STRUCTURE OF THE HYPC-HYPD COMPLEX | [NIFE] HYDROGENASE MATURATION, METAL BINDING PROTEIN
4lv9:B (THR468) to (ALA480) FRAGMENT-BASED IDENTIFICATION OF AMIDES DERIVED FROM TRANS-2-(PYRIDIN- 3-YL)CYCLOPROPANECARBOXYLIC ACID AS POTENT INHIBITORS OF HUMAN NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4m06:A (VAL12) to (LEU28) CRYSTAL STRUCTURE OF MUTANT CHLORITE DISMUTASE FROM CANDIDATUS NITROSPIRA DEFLUVII W145F IN COMPLEX WITH CYANIDE | FERREDOXIN-LIKE FOLD, OXIDOREDUCTASE
4m07:C (VAL12) to (LEU28) CRYSTAL STRUCTURE OF MUTANT CHLORITE DISMUTASE FROM CANDIDATUS NITROSPIRA DEFLUVII W145F | FERREDOXIN-LIKE FOLD, OXIDOREDUCTASE
4m07:D (VAL12) to (LEU28) CRYSTAL STRUCTURE OF MUTANT CHLORITE DISMUTASE FROM CANDIDATUS NITROSPIRA DEFLUVII W145F | FERREDOXIN-LIKE FOLD, OXIDOREDUCTASE
5a5b:S (LYS400) to (SER415) STRUCTURE OF THE 26S PROTEASOME-UBP6 COMPLEX | HYDROLASE, CONFORMATIONAL SWITCHING, PROTEIN DEGRADATION, PROTEOSTASIS, QUALITY CONTROL, UBP6, USP14
4m23:A (THR9) to (ALA32) CRYSTAL STRUCTURE OF NON-HEME IRON OXYGENASE ORFP | HYDROXYLASE, FE BINDING, OXIDOREDUCTASE
4m23:D (PRO10) to (ALA32) CRYSTAL STRUCTURE OF NON-HEME IRON OXYGENASE ORFP | HYDROXYLASE, FE BINDING, OXIDOREDUCTASE
1uh9:A (ASP120) to (SER145) CRYSTAL STRUCTURE OF RHIZOPUSPEPSIN AT PH 7.0 | PEPSIN, ASPARTIC PROTEINASE, HYDROLASE
4m2i:B (THR9) to (ALA32) CRYSTAL STRUCTURE OF NON-HEME IRON OXYGENASE ORFP IN COMPLEX WITH FE | HYDROXYLASE, FE BINDING, OXIDOREDUCTASE
1iiq:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR | HIV PROTEASE, PEPTIDOMIMETICS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1iq0:A (LEU78) to (ARG93) THERMUS THERMOPHILUS ARGINYL-TRNA SYNTHETASE | ARGINYL-TRNA SYNTHETASE, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, LIGASE
1iq0:A (ASP235) to (GLY247) THERMUS THERMOPHILUS ARGINYL-TRNA SYNTHETASE | ARGINYL-TRNA SYNTHETASE, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS, LIGASE
2ien:B (ASN183) to (GLY194) CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE WITH A POTENT NON-PEPTIDE INHIBITOR (UIC-94017) | HIV-1 PROTEASE, DIMER, INHIBITOR, UIC-94017, TMC114, DARUNAVIR, HYDROLASE
1j9z:B (HIS601) to (ASP612) CYPOR-W677G | NADPH-CYTOCHROME P450 REDUCTASE, OXIDOREDUCTASE
4mkf:A (ARG79) to (VAL90) CRYSTAL STRUCTURE OF A STABLE ADENYLATE KINASE VARIANT AKV3 | ADENYLATE KINASE, ZINC FINGER, TRANSFERASE ACTIVITY, PHOSPHOTRANSFERASE ACTIVITY, ZINC BINDING, ATP BINDING, PHOSPHORYLATION, TRANSFERASE
2xal:B (GLU2) to (ASP12) LEAD DERIVATIVE OF INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2- KINASE FROM A. THALIANA IN COMPLEX WITH ADP AND IP6. | TRANSFERASE, INOSITOL POLYPHOSPHATE KINASE, PHYTIC ACID SYNTHASE
2xh4:B (GLY376) to (ARG391) ENGINEERING THE ENOLASE ACTIVE SITE POCKET: CRYSTAL STRUCTURE OF THE S39A D321A MUTANT OF YEAST ENOLASE 1 | LYASE, TIM-BARREL, ENOLASE SUPERFAMILY, GLYCOLYSIS, GLUCONEOGENESIS, METAL BINDING
2xhb:A (TYR663) to (GLY690) CRYSTAL STRUCTURE OF DNA POLYMERASE FROM THERMOCOCCUS GORGONARIUS IN COMPLEX WITH HYPOXANTHINE-CONTAINING DNA | TRANSFERASE-DNA COMPLEX, REPLICATION, EXONUCLEASE, DNA DAMAGE, EXO MINUS
4myu:A (HIS675) to (ILE688) CRYSTAL STRUCTURE OF ELONGATION FACTOR G MUTANT(EFG) | ELONGATION FACTOR G, EFG, TRANSLATION
1w5v:B (ASN83) to (GLY94) HIV-1 PROTEASE IN COMPLEX WITH FLUORO SUBSTITUTED DIOL- BASED C2-SYMMETRIC INHIBITOR | HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE, DIMER, PROTEIN-INHIBITOR COMPLEX
2ji5:A (SER998) to (VAL13) STRUCTURE OF UMP KINASE FROM PYROCOCCUS FURIOSUS COMPLEXED WITH UTP | AMINO ACID KINASE, PHOSPHOTRANSPHERASE, ALLOSTERIC REGULATION, PYRIMIDINE METABOLISM, KINASE, UMP KINASE, TRANSFERASE, URIDYLATE KINASE, PYRIMIDINE BIOSYNTHESIS
2ji5:B (ILE3) to (VAL13) STRUCTURE OF UMP KINASE FROM PYROCOCCUS FURIOSUS COMPLEXED WITH UTP | AMINO ACID KINASE, PHOSPHOTRANSPHERASE, ALLOSTERIC REGULATION, PYRIMIDINE METABOLISM, KINASE, UMP KINASE, TRANSFERASE, URIDYLATE KINASE, PYRIMIDINE BIOSYNTHESIS
4nk7:A (VAL471) to (THR499) CRYSTAL STRUCTURE OF THE D. MELANOGASTER PLK4 CRYPTIC POLO BOX (CPB) | CRYPTIC POLO BOX, PLK4 TARGETING, ROCENTRIOLES, ASTERLESS N-TERMINUS, CENTROSOMES, TRANSFERASE
1ke2:A (GLY354) to (SER367) PSEUDOMONAS SERINE-CARBOXYL PROTEINASE COMPLEXED WITH THE INHIBITOR CHYMOSTATIN (THIS ENZYME RENAMED "SEDOLISIN" IN 2003) | SERINE-CARBOXYL PROTEINASE, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1woy:A (ASP90) to (GLY115) CRYSTAL STRUCTURE OF METHIONYL TRNA SYNTHETASE Y225F MUTANT FROM THERMUS THERMOPHILUS | LIGASE, METAL-BINDING, CLASS 1A AMINOACYL-TRNA SYNTHETASE, ROSSMANN FOLD, MUTATION AT TYR225, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
1kjf:B (ASN83) to (GLY94) SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES | P1-P6, SUBSTRATE RECOGNITION, HYDROLASE
2min:B (ALA67) to (LEU80) NITROGENASE MOFE PROTEIN FROM AZOTOBACTER VINELANDII, OXIDIZED STATE | NITROGEN FIXATION, NITROGEN METABOLISM, OXIDOREDUCTASE, MOLYBDOENZYMES, BIOLOGICAL NITROGEN FIXATION
2mlz:A (GLU124) to (GLN148) NMR STRUCTURE OF E. COLI TRIGGER FACTOR IN COMPLEX WITH UNFOLDED PHOA365-471 | MOLECULAR CHAPERONE, UNFOLDED PROTEIN, CHAPERONE
1xdp:A (GLN106) to (GLN129) CRYSTAL STRUCTURE OF THE E.COLI POLYPHOSPHATE KINASE IN COMPLEX WITH AMPPNP | E.COLI POLYPHOSPHATE KINASE, PPK, PPK COMPLEX WITH AMPPNP, AMPPNP, TRANSFERASE
5ccl:A (GLY194) to (ASN205) CRYSTAL STRUCTURE OF SMYD3 WITH SAM AND OXINDOLE COMPOUND | PROTEIN-INHIBITOR COMPLEX, METHYLTRANSFERASE, EPIGENETICS, DRUG DISCOVERY, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4a3k:E (PHE60) to (PRO73) RNA POLYMERASE II INITIAL TRANSCRIBING COMPLEX WITH A 7NT DNA-RNA HYBRID | TRANSCRIPTION, TRANSCRIPTION INITIATION
1xmg:A (PHE359) to (ASN375) CRYSTAL STRUCTURE OF APO METHANE MONOOXYGENASE HYDROXYLASE FROM M. CAPSULATUS (BATH) | APO PROTEIN; FOUR-HELIX BUNDLE; METHANE; DIIRON; MMOH, OXIDOREDUCTASE
1xmg:B (PHE359) to (ASN375) CRYSTAL STRUCTURE OF APO METHANE MONOOXYGENASE HYDROXYLASE FROM M. CAPSULATUS (BATH) | APO PROTEIN; FOUR-HELIX BUNDLE; METHANE; DIIRON; MMOH, OXIDOREDUCTASE
2zbl:D (ALA106) to (GLY127) FUNCTIONAL ANNOTATION OF SALMONELLA ENTERICA YIHS-ENCODED PROTEIN | N-ACYL-D-GLUCOSAMINE 2-EPIMERASE PROTEIN FAMILY, ISOMERASE
3kdc:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, L33I, L63I) IN COMPLEX WITH KNI-10074 | VIRAL PROTEIN, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3kdc:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE (Q7K, L33I, L63I) IN COMPLEX WITH KNI-10074 | VIRAL PROTEIN, HYDROLASE, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3ken:A (ILE19) to (SER36) HUMAN EG5 IN COMPLEX WITH S-TRITYL-L-CYSTEINE | CELL CYCLE, KINESIN-INHIBITOR COMPLEX, MOTOR DOMAIN, L5 LOOP, ATP- BINDING, CELL DIVISION, COILED COIL, MICROTUBULE, MITOSIS, MOTOR PROTEIN, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN
3kfs:A (ASN83) to (GLY94) HIV PROTEASE (PR) DIMER WITH INHIBITOR TL-3 BOUND AND FRAGMENT 2F4 IN THE OUTSIDE/TOP OF FLAP | HIV-1, PROTEASE, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5cz9:F (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA5-D17N MUTANT IN COMPLEX WITH CARFILZOMIB; PROPEPTIDE EXPRESSED IN TRANS | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
5cz9:T (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA5-D17N MUTANT IN COMPLEX WITH CARFILZOMIB; PROPEPTIDE EXPRESSED IN TRANS | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
5czt:A (SER160) to (SER171) NEISSERIA MENINGITIDIS 3 DEXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE GLU176ALA VARIANT | DAH7PS, ALLOSTERY, TRANSFERASE
1mja:A (ILE402) to (ALA418) CRYSTAL STRUCTURE OF YEAST ESA1 HISTONE ACETYLTRANSFERASE DOMAIN COMPLEXED WITH ACETYL COENZYME A | ESA1, HISTONE ACETYLTRANSFERASE, HAT, MYST, TRANSFERASE
3aal:A (LYS173) to (GLY187) CRYSTAL STRUCTURE OF ENDONUCLEASE IV FROM GEOBACILLUS KAUSTOPHILUS | ENDOIV, DNA REPAIR, BASE EXCISION REPAIR, TIM BARREL, DNA DAMAGE, ENDONUCLEASE, HYDROLASE, METAL-BINDING, NUCLEASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
4pfh:B (GLY60) to (ASP74) CRYSTAL STRUCTURE OF ENGINEERED D-TAGATOSE 3-EPIMERASE PCDTE-IDF8 | EPIMERASE, TIM-BARREL, ISOMERASE
5djc:A (GLN342) to (ASN361) FC HETERODIMER DESIGN 8.1 L368V/Y407A + T366V/K409F | HETERODIMER, IMMUNOGLOBULIN, CH3, FC, BISPECIFIC ANTIBODY, IMMUNE SYSTEM
4po7:A (SER426) to (LYS438) STRUCTURE OF THE SORTILIN:NEUROTENSIN COMPLEX AT EXCESS NEUROTENSIN CONCENTRATION | 10 BLADED BETA-PROPELLER, PROTEIN SORTING RECEPTOR, NEUROTENSIN, GLYCOSYLATION, TRANS GOLGI NETWORK, PROTEIN BINDING
4pt0:A (VAL51) to (PHE70) NAD+ COMPLEX STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS | ALDEHYDE DEHYDROGENASE, NAD+-COMPLEX STRUCTURE, NAD+, ROSSMANN FOLD, OXIDOREDUCTASE
4pt0:B (VAL51) to (PHE70) NAD+ COMPLEX STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS | ALDEHYDE DEHYDROGENASE, NAD+-COMPLEX STRUCTURE, NAD+, ROSSMANN FOLD, OXIDOREDUCTASE
4pt0:C (VAL51) to (PHE70) NAD+ COMPLEX STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS | ALDEHYDE DEHYDROGENASE, NAD+-COMPLEX STRUCTURE, NAD+, ROSSMANN FOLD, OXIDOREDUCTASE
4pt0:D (VAL51) to (PHE70) NAD+ COMPLEX STRUCTURE OF ALDEHYDE DEHYDROGENASE FROM BACILLUS CEREUS | ALDEHYDE DEHYDROGENASE, NAD+-COMPLEX STRUCTURE, NAD+, ROSSMANN FOLD, OXIDOREDUCTASE
1za2:A (VAL122) to (GLY150) STRUCTURE OF WILD-TYPE E. COLI ASPARTATE TRANSCARBAMOYLASE IN THE PRESENCE OF CTP, CARBAMOYL PHOSPHATE AT 2.50 A RESOLUTION | ORDERED SUBSTRATE BINDING, COOPERATIVITY, TRANSFERASE
1za2:C (VAL122) to (ILE145) STRUCTURE OF WILD-TYPE E. COLI ASPARTATE TRANSCARBAMOYLASE IN THE PRESENCE OF CTP, CARBAMOYL PHOSPHATE AT 2.50 A RESOLUTION | ORDERED SUBSTRATE BINDING, COOPERATIVITY, TRANSFERASE
4pvu:A (GLN345) to (LEU356) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN PPARGAMMA-LBD AND THE R ENANTIOMER OF MBX-102 (METAGLIDASEN) | ALPHA-HELICES, SMALL FOUR-STRANDED BETA-SHEET, ACTIVATOR, TDNA- BINDING, NUCLEUS, OBESITY, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION
1zbg:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF A COMPLEX OF MUTANT HIV-1 PROTEASE (A71V, V82T, I84V) WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR BOC-PHE- PSI[R-CH(OH)CH2NH]-PHE-GLU-PHE-NH2 | HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ap0:B (ASN18) to (SER36) THE MITOTIC KINESIN EG5 IN COMPLEX WITH MG-ADP AND ISPINESIB | MOTOR PROTEIN
4app:A (PRO470) to (ARG489) CRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 4 IN COMPLEX WITH (S)-N-(5-(3-BENZYL-1-METHYLPIPERAZINE-4- CARBONYL)-6,6-DIMETHYL-1,4,5,6-TETRAHYDROPYRROLO(3,4-C) PYRAZOL-3-YL)-3-PHENOXYBENZAMIDE | TRANSFERASE, PROTEIN KINASE
1zm4:C (GLY217) to (GLY234) STRUCTURE OF THE EEF2-ETA-BTAD COMPLEX | ELONGATION FACTOR, TOXIN, ADP-RIBOSYLATION, BIOSYNTHETIC PROTEIN/TRANSFERASE COMPLEX
5dyl:A (LYS375) to (LEU388) CRYSTAL STRUCTURE OF PVX_084705 | TRANSFERASE, KINASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
1zpk:A (ASN83) to (GLY94) CRYSTAL STRUCTURE OF THE COMPLEX OF MUTANT HIV-1 PROTEASE (A71V, V82T, I84V) WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR BOC-PHE- PSI[R-CH(OH)CH2NH]-PHE-GLU-PHE-NH2 | HIV, PROTEASE, PEPTIDOMIMETIC INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4q7i:A (GLY60) to (ASP74) CRYSTAL STRUCTURE OF ENGINEERED THERMOSTABLE D-TAGATOSE 3-EPIMERASE PCDTE-VAR8 | EPIMERASE, TIM-BARREL, ISOMERASE
4qbi:A (ARG79) to (VAL90) CRYSTAL STRUCTURE OF A STABLE ADENYLATE KINASE VARIANT AKLSE6 | ADENYLATE KINASE, ZINC FINGER, TRANSFERASE ACTIVITY, PHOSPHOTRANSFERASE ACTIVITY, ZINC BINDING, ATP BINDING, PHOSPHORYLATION, TRANSFERASE
2a8n:B (ASP127) to (LEU141) BIOCHEMICAL AND STRUCTURAL STUDIES OF A-TO-I EDITING BY TRNA:A34 DEAMINASES AT THE WOBBLE POSITION OF TRANSFER RNA | RNA EDITING, RNA BINDING PROTEIN
4ql5:B (LEU33) to (TYR44) CRYSTAL STRUCTURE OF TRANSLATION INITIATION FACTOR IF-1 FROM STREPTOCOCCUS PNEUMONIAE TIGR4 | TRANSLATION INITIATION FACTOR, PROTEIN BIOSYNTHESIS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, CSGID, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, STRUCTURAL GENOMICS, BETA BARREL, OB FOLD, TRANSLATION
3moh:A (MET173) to (GLY185) THE STRUCTURE OF RAT CYTOSOLIC PEPCK MUTANT A467G IN COMPLEX WITH PHOSPHOGLYCOLATE AND GDP | KINASE, GLUCONEOGENESIS, LYASE
5ex3:A (GLY194) to (ASN205) CRYSTAL STRUCTURE OF HUMAN SMYD3 IN COMPLEX WITH A VEGFR1 PEPTIDE | SET DOMAIN, METHYLATION, CHROMATIN, CANCER, TRANSFERASE
4qw3:T (HIS224) to (ASN244) YCP BETA5-C63F MUTANT IN COMPLEX WITH BORTEZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qw7:F (HIS224) to (ASN244) YCP BETA5-M45T MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qw7:T (HIS224) to (ASN244) YCP BETA5-M45T MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qwi:F (HIS224) to (ASN244) YCP BETA5-A49S-MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qwi:T (HIS224) to (ASN244) YCP BETA5-A49S-MUTANT IN COMPLEX WITH CARFILZOMIB | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5f2v:S (PHE42) to (ARG59) CRYSTAL STRUCTURE OF THE SMALL ALARMONE SYNTHETHASE 1 FROM BACILLUS SUBTILIS BOUND TO AMPCPP | (P)PPGPP, ALARMONE, STRINGENT RESPONSE, ALLOSTERIC REGULATOR, TRANSFERASE
4qz1:F (HIS224) to (ASN244) YCP BETA5-M45T MUTANT IN COMPLEX WITH THE EPOXYKETONE INHIBITOR ONX 0914 | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qz1:T (HIS224) to (ASN244) YCP BETA5-M45T MUTANT IN COMPLEX WITH THE EPOXYKETONE INHIBITOR ONX 0914 | CANCER, PROTEASOME, BORTEZOMIB, DRUG RESISTANCE, BINDING ANALYSIS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4r14:A (VAL39) to (GLU62) CRYSTAL STRUCTURE OF HUMAN CSN6 MPN DOMAIN | MPN DOMAIN, PROTEIN-PROTEIN INTERACTION, PROTEIN BINDING
4r14:B (VAL39) to (GLN61) CRYSTAL STRUCTURE OF HUMAN CSN6 MPN DOMAIN | MPN DOMAIN, PROTEIN-PROTEIN INTERACTION, PROTEIN BINDING
5fc9:D (ALA4003) to (ASP4013) NOVEL PURPLE CUPREDOXIN FROM NITROSOPUMILUS MARITIMUS | CUPREDOXIN, NO OXIDATION, NITROGEN CYCLE, OPEN TYPE 1 COPPER SITE, METAL BINDING PROTEIN
4bx9:B (LYS285) to (ILE299) HUMAN VPS33A IN COMPLEX WITH A FRAGMENT OF HUMAN VPS16 | PROTEIN TRANSPORT, HOPS, MEMBRANE TRAFFICKING, SEC1/MUNC18 PROTEINS, TETHERING
5fgg:F (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA5-L(-49S)_D17N DOUBLE MUTANT IN COMPLEX WITH CARFILZOMIB | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
5fgg:T (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA5-L(-49S)_D17N DOUBLE MUTANT IN COMPLEX WITH CARFILZOMIB | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
3c4u:A (PRO43) to (TYR55) STRUCTURE OF CLASS II FRUCTOSE-BIPHOSPHATE ALDOLASE FROM HELICOBACTER PYLORI | FBP ALDOLASE, CLASS II, ZINC, GLYCOLYSIS, LYASE, METAL- BINDING
3c56:A (PRO43) to (MET56) CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE FROM HELICOBACTER PYLORI IN COMPLEX WITH N-(3-HYDROXYPROPYL)- GLYCOLOHYDROXAMIC ACID BISPHOSPHATE, A COMPETITIVE INHIBITOR | CLASS II, FBP, ALDOLASE, GLYCOLYSIS, INHIBITOR, LYASE, METAL-BINDING, ZINC
5fgi:F (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA1-T1A BETA2-T1A DOUBLE MUTANT IN COMPLEX WITH CARFILZOMIB | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
5fgi:T (HIS224) to (ASN244) YEAST 20S PROTEASOME BETA1-T1A BETA2-T1A DOUBLE MUTANT IN COMPLEX WITH CARFILZOMIB | HYDROLASE-HYDROLASE INHIBITOR COMPLEX, PROTEASOME, MUTANT, INHIBITOR, BINDING ANALYSIS
5fh0:A (MET173) to (GLY185) THE STRUCTURE OF RAT CYTOSOLIC PEPCK VARIANT E89A COMPLEX WITH GTP | KINASE, GLUCONEOGENESIS, LYASE
3ngt:L (GLU4) to (GLY18) STRUCTURE OF LEISHMANIA NDKB COMPLEXED WITH AMP. | LMNDKB, AMP, TRANSFERASE
3nls:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH KNI-10772 | PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3nu4:B (ASN183) to (GLY194) CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT V32I WITH ANTIVIRAL DRUG AMPRENAVIR | ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, CONFORMATIONAL CHANGE, AMPRENAVIR, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4cp7:B (ASN183) to (GLY194) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN, ENZYME
3d1y:B (ASN183) to (GLY194) CRYSTAL STRUCTURE OF HIV-1 MUTANT I54V AND INHIBITOR SAQUINA | DRUG RESISTANCE, HIV-1, I54V, FLAP MUTANT, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4cpq:B (ASN183) to (GLY194) MACROCYCLIC TRANSITION-STATE MIMICKING HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL | HYDROLASE, INHIBITOR, RATIONAL DRUG DESIGN
4cr2:O (ASN304) to (HIS318) DEEP CLASSIFICATION OF A LARGE CRYO-EM DATASET DEFINES THE CONFORMATIONAL LANDSCAPE OF THE 26S PROTEASOME | HYDROLASE, AAA-ATPASE, ATP-ANALOG, CLASSIFICATION
4cr2:V (THR23) to (VAL45) DEEP CLASSIFICATION OF A LARGE CRYO-EM DATASET DEFINES THE CONFORMATIONAL LANDSCAPE OF THE 26S PROTEASOME | HYDROLASE, AAA-ATPASE, ATP-ANALOG, CLASSIFICATION
3d6d:B (GLN345) to (LEU356) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN PPARGAMMA LBD AND THE LT175(R-ENANTIOMER) | BUNDLE OF ALPHA-HELICES AND A SMALL FOUR-STRANDED BETA- SHEET, ACTIVATOR, ALTERNATIVE SPLICING, DIABETES MELLITUS, DISEASE MUTATION, DNA-BINDING, METAL-BINDING, NUCLEUS, OBESITY, PHOSPHOPROTEIN, POLYMORPHISM, RECEPTOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, ZINC, ZINC-FINGER
4tn0:B (LYS476) to (ASN491) CRYSTAL STRUCTURE OF THE C-TERMINAL PERIPLASMIC DOMAIN OF PHOSPHOETHANOLAMINE TRANSFERASE EPTC FROM CAMPYLOBACTER JEJUNI | ALKALINE PHOSPHATASE-LIKE, PHOSPHOETHANOLAMINE TRANSFERASE, PHOSPHOTHREONINE, PERIPLASM, TRANSFERASE
3dcy:A (GLN0) to (LYS20) CRYSTAL STRUCTURE A TP53-INDUCED GLYCOLYSIS AND APOPTOSIS REGULATOR PROTEIN FROM HOMO SAPIENS. | OMIM 610775, C12ORF5, TIGAR, TP53-INDUCED GLYCOLYSIS AND APOPTOSIS REGULATOR, CASP TARGET, STRUCTURAL GENOMICS MEDICAL RELEVANCE, PROTEIN STRUCTURE INITIATIVE, PSI, CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS, CESG, ISOMERASE, PHOSPHOPROTEIN
3dkl:B (THR468) to (ALA480) CRYSTAL STRUCTURE OF PHOSPHORYLATED MIMIC FORM OF HUMAN NAMPT COMPLEXED WITH BENZAMIDE AND PHOSPHORIBOSYL PYROPHOSPHATE | TRANSFERASE, NMPRTASE, VISFATIN, NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE, BERYLLIUM FLUORIDE, BENZAMIDE, PHOSPHORIBOSYL PYROPHOSPHATE, ALTERNATIVE SPLICING, CYTOPLASM, GLYCOSYLTRANSFERASE, PHOSPHOPROTEIN, POLYMORPHISM, PYRIDINE NUCLEOTIDE BIOSYNTHESIS
3oks:A (SER8) to (ALA30) CRYSTAL STRUCTURE OF 4-AMINOBUTYRATE TRANSAMINASE FROM MYCOBACTERIUM SMEGMATIS | SSGCID, TRANSFERASE, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3oks:B (SER8) to (ALA30) CRYSTAL STRUCTURE OF 4-AMINOBUTYRATE TRANSAMINASE FROM MYCOBACTERIUM SMEGMATIS | SSGCID, TRANSFERASE, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3oks:C (SER8) to (ALA30) CRYSTAL STRUCTURE OF 4-AMINOBUTYRATE TRANSAMINASE FROM MYCOBACTERIUM SMEGMATIS | SSGCID, TRANSFERASE, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
3oks:D (SER8) to (ALA30) CRYSTAL STRUCTURE OF 4-AMINOBUTYRATE TRANSAMINASE FROM MYCOBACTERIUM SMEGMATIS | SSGCID, TRANSFERASE, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
4txi:A (GLY42) to (LEU55) CONSTRUCT OF MICAL-1 CONTAINING THE MONOOXYGENASE AND CALPONIN HOMOLOGY DOMAINS | MONOOXYGENASE, CALPONIN HOMOLOGY, MICAL, OXIDOREDUCTASE
4d9b:A (ILE250) to (GLY260) PYRIDOXAMINE 5' PHOSPHATE (PMP) BOUND FORM OF SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE OBTAINED AFTER CO-CRYSTALLIZATION WITH D- CYCLOSERINE | FOLD TYPE II PLP-DEPENDENT ENZYME OR TRYPTOPHAN SYNTHASE BETA SUBUNIT LIKE FAMILY, PLP DEPENDENT ENZYME, LYASE
4d9b:B (ILE250) to (GLY260) PYRIDOXAMINE 5' PHOSPHATE (PMP) BOUND FORM OF SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE OBTAINED AFTER CO-CRYSTALLIZATION WITH D- CYCLOSERINE | FOLD TYPE II PLP-DEPENDENT ENZYME OR TRYPTOPHAN SYNTHASE BETA SUBUNIT LIKE FAMILY, PLP DEPENDENT ENZYME, LYASE
4d9b:C (ILE250) to (GLY260) PYRIDOXAMINE 5' PHOSPHATE (PMP) BOUND FORM OF SALMONELLA TYPHIMURIUM D-CYSTEINE DESULFHYDRASE OBTAINED AFTER CO-CRYSTALLIZATION WITH D- CYCLOSERINE | FOLD TYPE II PLP-DEPENDENT ENZYME OR TRYPTOPHAN SYNTHASE BETA SUBUNIT LIKE FAMILY, PLP DEPENDENT ENZYME, LYASE
3dtb:B (MET173) to (GLY185) THE STRUCTURE OF RAT CYTOSOLIC PEPCK IN COMPLEX WITH PHOSPHOGLYCOLATE AND GDP | KINASE, GLUCONEOGENESIS, LYASE, DECARBOXYLASE, GTP-BINDING, NUCLEOTIDE-BINDING
3ou3:A (ASN83) to (GLY94) MDR769 HIV-1 PROTEASE COMPLEXED WITH PR/RT HEPTA-PEPTIDE | MDR HIV-1 PROTEASE, INHIBITOR, DRUG RESISTANCE, SUBSTRATE ENVELOPE, HIV-1 PROTEASE, PROTEASE, PR/RT SUBSTRATE PEPTIDE, NONE, HYDROLASE, HYDROLASE-PEPTIDE COMPLEX
3oxc:B (ASN183) to (GLY194) WILD TYPE HIV-1 PROTEASE WITH ANTIVIRAL DRUG SAQUINAVIR | ENZYME INHIBITION, ASPARTIC PROTEASE, HIV/AIDS, SAQUINAVIR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3e2p:A (VAL119) to (GLY147) CATALYTIC SUBUNIT OF M. JANNASCHII ASPARTATE TRANSCARBAMOYLASE IN AN ORTHORHOMBIC CRYSTAL FORM | ASPARTATE TRANSCARBAMOYLASE, ATCASE, PYRIMIDINE BIOSYNTHESIS, THERMOSTABILITY, METHANOCOCCUS JANNASCHII, CRYSTAL STRUCTURE, TRANSFERASE
3e2p:K (VAL119) to (GLY147) CATALYTIC SUBUNIT OF M. JANNASCHII ASPARTATE TRANSCARBAMOYLASE IN AN ORTHORHOMBIC CRYSTAL FORM | ASPARTATE TRANSCARBAMOYLASE, ATCASE, PYRIMIDINE BIOSYNTHESIS, THERMOSTABILITY, METHANOCOCCUS JANNASCHII, CRYSTAL STRUCTURE, TRANSFERASE
4dqc:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF (G16C/L38C) HIV-1 PROTEASE IN COMPLEX WITH DRV | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4dqh:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF (R14C/E65C) HIV-1 PROTEASE IN COMPLEX WITH DRV | HIV-1 PROTEASE, DRUG RESISTANCE, DRUG DESIGN, PROTEASE INHIBITORS, AIDS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5hwx:A (MET252) to (SER278) STRUCTURAL MECHANISMS OF EXTRACELLULAR ION EXCHANGE AND INDUCED BINDING-SITE OCCLUSION IN THE SODIUM-CALCIUM EXCHANGER NCX_MJ SOAKED WITH 2.5 MM NA+ AND ZERO CA2+ | NA+/CA2+ EXCHANGE, CALCIUM SIGNALLING, MEMBRANE TRANSPORTER, INDUCED CONFORMATIONAL CHANGE, MEMBRANE PROTEIN
3pco:C (THR216) to (PHE234) CRYSTAL STRUCTURE OF E. COLI PHENYLALANINE-TRNA SYNTHETASE COMPLEXED WITH PHENYLALANINE AND AMP | AMINOACYLATION, TRNA-BINDING, DNA-BINDING DOMAIN, FOUR-HELIX BUNDLE, AMINOACYL-TRNA SYNTHETASE, ATP-BINDING, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS
3peq:B (SER345) to (SER355) PPARD COMPLEXED WITH A PHENOXYACETIC ACID PARTIAL AGONIST | PPAR NUCLEAR RECEPTOR, TRANSCRIPTION-TRANSCRIPTION AGONIST COMPLEX
4e43:B (ASN83) to (GLY94) HIV PROTEASE (PR) DIMER WITH ACETATE IN EXO SITE AND PEPTIDE IN ACTIVE SITE | HIV-1 PROTEASE, EXO SITE, ASPARTYL PROTEASE, FRAGMENT SCREEN, HYDROLASE
5ivq:B (ASN83) to (GLY94) CRYSTAL STRUCTURE OF HIV PROTEASE COMPLEXED WITH METHYL N-[(1S)-1- BENZHYDRYL-2-(3-MORPHOLIN-4-IUM-2-YLPROPYLAMINO)-2-OXO- ETHYL]CARBAMATE | HIV, PROTEASE, HYDROLASE-INHIBITOR COMPLEX
3qaa:B (ASN183) to (GLY194) HIV-1 WILD TYPE PROTEASE WITH A SUBSTITUTED BIS-TETRAHYDROFURAN INHIBITOR, GRL-044-10A | ASPARTIC ACID PROTEASE, HIV-1 PROTEASE INHIBITOR GRL-044-10A, SUBSTITUTED BIS-TETRAHYDROFURAN INHIBITOR, WILD-TYPE HIV-1 PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3qfc:A (HIS604) to (ARG616) CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 (V492E MUTANT) | HUMAN CYPOR, CYTOCHROME P450 REDUCTASE, FLAVOPROTEIN, FAD, FMN, NADPH, OXIDOREDUCTASE
3qfc:B (HIS604) to (ASP615) CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 (V492E MUTANT) | HUMAN CYPOR, CYTOCHROME P450 REDUCTASE, FLAVOPROTEIN, FAD, FMN, NADPH, OXIDOREDUCTASE
5jkn:A (GLU159) to (ILE177) CRYSTAL STRUCTURE OF DEUBIQUITINASE MINDY-1 | HYDROLASE, CYSTEINE PROTEASE, ISOPEPTIDASE AND UBIQUITIN BINDING
3rhp:A (CYS451) to (PHE472) CRYSTAL STRUCTURE OF THE C707A MUTANT OF THE C-TERMINAL DOMAIN OF 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE | FDH, OXIDOREDUCTASE
3rhp:C (CYS451) to (PHE472) CRYSTAL STRUCTURE OF THE C707A MUTANT OF THE C-TERMINAL DOMAIN OF 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE | FDH, OXIDOREDUCTASE
5jod:A (ASP121) to (ASN147) STRUCTURE OF PROPLASMEPSIN IV FROM PLASMODIUM FALCIPARUM | MALARIA, HYDROLASE
4fyw:C (VAL122) to (ILE145) E. COLI ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH CTP | PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS, FEEDBACK INHIBITION, ALLOSTERY, TRANSFERASE
5k1a:B (THR513) to (GLY535) CRYSTAL STRUCTURE OF THE UAF1-USP12 COMPLEX IN C2 SPACE GROUP | WD40 DOMAIN, UBIQUITIN-SPECIFIC PROTEASE 12, USP12, USP1-ASSOCIATED FACTOR 1, USP1, DEUBIQUITINATING ENZYME, DUB, SUMO-LIKE DOMAIN, SLD, HYDROLASE
5k8n:C (PHE331) to (VAL356) 5NAA-BOUND 5-NITROANTHRANILATE AMINOHYDROLASE | NITROAROMATICS, DEAMINASE, METALLOENZYME, HYDROLASE
5kqz:B (ASN83) to (GLY94) PROTEASE E35D-CAP2 | HIV-1 PROTEASE, E35D, SALT-BRIDGE INTERACTION, NATURAL POLYMORPHISM, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5l4k:R (ARG312) to (GLY324) THE HUMAN 26S PROTEASOME LID | PROTEOSTASIS, AAA-ATPASE, STRUCTURAL PROTEIN
7nse:B (VAL417) to (GLY441) BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE, H4B-FREE, ADMA COMPLEX | NITRIC OXIDE SYNTHASE, HEME PROTEIN, TETRAHYDROBIOPTERIN, OXIDOREDUCTASE
8at1:A (VAL122) to (THR148) CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H | TRANSFERASE (CARBAMOYL-P,ASPARTATE)
8at1:C (VAL122) to (THR148) CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H | TRANSFERASE (CARBAMOYL-P,ASPARTATE)