Protein Concepts Dictionary

Tableau information

Concept source:  d4e5ob_  amino acid (a.a.) range (ASP104)(GLY294)

nSSEs in this Concept: 16

String of secondary struct.elems. (SSEs) defining this concept: HHHHEHHEEEHEEHEE

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (ASP104)  (SER108) H1
	  (SER108)  (GLY116) H2
	  (VAL128)  (ARG134) H3
	  (GLN154)  (THR164) H4
	  (ILE171)  (ALA175) E5
	  (ASN177)  (ASP180) H6
	  (ASP180)  (MET184) H7
	  (LEU192)  (VAL197) E8
	  (GLU201)  (TYR207) E9
	  (ARG209)  (ASP212) E10
	  (ASP212)  (THR235) H11
	  (ASP241)  (GLY247) E12
	  (GLY247)  (TYR252) E13
	  (ILE256)  (GLN264) H14
	  (LYS272)  (ARG277) E15
	  (ASP289)  (GLY294) E16

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                                                                                                              
H2      -57.1°   H2                                                                                                       
H3     -105.3°  -70.7°   H3                                                                                                
H4      148.7°   95.2°   46.7°   H4                                                                                         
E5       40.4°   89.6°  144.2° -169.0°   E5                                                                                  
H6       56.2°  100.2°  160.2° -153.1°   16.2°   H6                                                                           
H7       96.1°  138.7°  150.6° -115.1°  -56.2°  -41.7°   H7                                                                    
E8     -152.8° -109.8°  -48.5°  -18.2°  160.5°  148.1°  106.3°   E8                                                             
E9       34.5°   58.7°  127.3°  144.7°  -34.2°  -41.7°  -81.3°  162.8°   E9                                                      
E10      88.2°  125.7° -163.3° -122.1°   47.8°   32.1°  -13.1° -116.5°   69.2°   E10                                              
H11    -112.8°  -97.1°  -28.6°  -51.4°  137.8°  145.9°  123.5°  -41.3°  145.4°  136.6°   H11                                       
E12      35.2°   51.5°  121.0°  138.4°  -41.4°  -49.0°  -88.0°  156.6°   -7.4°  -75.6°  141.8°   E12                                
E13      85.3°  124.6° -164.7° -125.2°   44.9°   29.3°  -14.2° -119.0°   67.4°   -3.1° -137.0°   74.0°   E13                         
H14    -170.1° -124.4°  -68.2°  -29.4°  143.7°  129.0°   87.6°  -19.7° -155.4°   97.1°   57.8° -154.5°  -99.7°   H14                  
E15     -77.6°  -95.1°  -56.9°  -92.2°   97.3°  108.1°  110.2°  -80.3°  111.9°  118.6°  -40.8°  112.6°  116.6°   92.4°   E15           
E16    -119.9°  103.6°  121.5°   77.8°  -91.5°  -77.2°  -60.1°   85.2°  -85.6°  -56.0°  126.5°  -86.2°  -58.8°   69.9°  159.4°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±4.1°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d3ihib_ :   (TRP103)  (HIS298)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d4iqqa_ :   (LYS101)  (ASP302)   [view usage] : d.117.1.0 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |automated matches |automated matches |Nematode (Caenorhabditis elegans) [TaxId: 6239]
 d2oipc2 :   (TRP316)  (GLY508)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |automated matches |Cryptosporidium hominis [TaxId: 237895]
 d2tsra_ :   (TRP103)  (GLY294)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d1qzfa2 :   (ASN306)  (GLY508)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain |Cryptosporidium hominis [TaxId: 237895]
 d4e5of_ :   (ASP104)  (GLY294)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d1hzwb_ :   (TRP109)  (HIS304)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase |Human (Homo sapiens) [TaxId: 9606]
 d4e5ob_ :   (ASP104)  (GLY294)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d3ihia_ :   (TRP103)  (HIS298)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |automated matches |Mouse (Mus musculus) [TaxId: 10090]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
 d.117