Protein Concepts Dictionary

Tableau information

Concept source:  d4npcb_  amino acid (a.a.) range (LYS17)(VAL68)

nSSEs in this Concept: 5

String of secondary struct.elems. (SSEs) defining this concept: EHEHE

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	   (LYS17)   (GLY23) E1
	   (ILE28)   (GLY40) H2
	   (LYS42)   (ILE48) E3
	   (ASP51)   (GLY61) H4
	   (ASN63)   (VAL68) E5

Orientation angles° of SSE-pairs; those in contact shown in bold font
          E1                                 
H2     -165.9°   H2                          
E3      -16.4° -165.6°   E3                   
H4      139.2°  -33.2°  155.5°   H4            
E5      -37.0°  151.6°  -21.1°  174.9°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±9.1°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d2q1wa_ :     (LYS3)   (GLU52)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Bordetella bronchiseptica [TaxId: 518]
 d1chda_ :   (GLU156)  (GLU213)   [view usage] : c.40.1.1 |Methylesterase CheB, C-terminal domain |Methylesterase CheB, C-terminal domain |Methylesterase CheB, C-terminal domain |Methylesterase CheB, C-terminal domain |Salmonella typhimurium [TaxId: 90371]
 d3wgka1 :    (LEU14)   (GLN60)   [view usage] : c.32.1.1 |Tubulin nucleotide-binding domain-like |Tubulin nucleotide-binding domain-like |Tubulin, GTPase domain |Cell-division protein FtsZ |Staphylococcus aureus [TaxId: 1280]
 d2d2fa_ :   (THR163)  (ASP219)   [view usage] : c.37.1.0 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |automated matches |automated matches |Thermus thermophilus HB8 [TaxId: 300852]
 d2rhha1 :    (ALA12)   (GLY62)   [view usage] : c.32.1.1 |Tubulin nucleotide-binding domain-like |Tubulin nucleotide-binding domain-like |Tubulin, GTPase domain |Cell-division protein FtsZ |Bacillus subtilis [TaxId: 1423]
 d2acvb_ :     (LYS8)   (ASP73)   [view usage] : c.87.1.10 |UDP-Glycosyltransferase/glycogen phosphorylase |UDP-Glycosyltransferase/glycogen phosphorylase |UDPGT-like |Triterpene UDP-glucosyl transferase UGT71G1 |Medicago truncatula [TaxId: 3880]
 d2b1lb_ :    (LYS69)  (ASP129)   [view usage] : c.47.1.10 |Thioredoxin fold |Thioredoxin-like |Glutathione peroxidase-like |automated matches |Escherichia coli [TaxId: 562]
 d1xdoa4 :   (SER531)  (VAL586)   [view usage] : d.136.1.4 |Phospholipase D/nuclease |Phospholipase D/nuclease |Polyphosphate kinase C-terminal domain |Polyphosphate kinase, PPK |Escherichia coli [TaxId: 562]
 d1j3la_ :    (ARG34)   (GLY93)   [view usage] : c.8.7.1 |The "swivelling" beta/beta/alpha domain |RraA-like |RraA-like |Demethylmenaquinone methyltransferase |Thermus thermophilus [TaxId: 274]
 d3of2a_ :     (ARG9)   (GLN66)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |Enoyl-ACP reductase |Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
 d2f5tx2 :   (ALA110)  (ILE165)   [view usage] : d.136.1.5 |Phospholipase D/nuclease |Phospholipase D/nuclease |TrmB middle domain-like |Transcriptional regulator TrmB |Thermococcus litoralis [TaxId: 2265]
 d2e55a_ :   (ILE123)  (GLY179)   [view usage] : c.61.1.0 |PRTase-like |PRTase-like |automated matches |automated matches |Aquifex aeolicus [TaxId: 63363]
 d2r6r11 :     (CYS8)   (GLY58)   [view usage] : c.32.1.1 |Tubulin nucleotide-binding domain-like |Tubulin nucleotide-binding domain-like |Tubulin, GTPase domain |Cell-division protein FtsZ |Aquifex aeolicus [TaxId: 224324]
 d1sowa1 :    (LYS21)   (ALA81)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Toxoplasma gondii [TaxId: 5811]
 d2ntva_ :     (ARG9)   (ASP64)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |Enoyl-ACP reductase |Mycobacterium leprae [TaxId: 1769]
 d1cdoa2 :   (SER194)  (ASN243)   [view usage] : c.2.1.1 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Alcohol dehydrogenase-like, C-terminal domain |Alcohol dehydrogenase |Cod (Gadus callarias) [TaxId: 8053]
 d1tpfa_ :     (GLN5)   (ALA64)   [view usage] : c.1.1.1 |TIM beta/alpha-barrel |Triosephosphate isomerase (TIM) |Triosephosphate isomerase (TIM) |Triosephosphate isomerase |Trypanosome (Trypanosoma brucei) [TaxId: 5691]
 d3u2wa_ :     (PHE6)   (ASP62)   [view usage] : c.68.1.14 |Nucleotide-diphospho-sugar transferases |Nucleotide-diphospho-sugar transferases |Glycogenin |Glycogenin |Human (Homo sapiens) [TaxId: 9606]
 d1nkva_ :    (THR38)   (HIS92)   [view usage] : c.66.1.21 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |Hypothetical Protein YjhP |Hypothetical Protein YjhP |Escherichia coli [TaxId: 562]
 d3t8ja_ :     (MET1)   (PRO62)   [view usage] : c.70.1.0 |Nucleoside hydrolase |Nucleoside hydrolase |automated matches |automated matches |Sulfolobus solfataricus [TaxId: 273057]
 d1k92a1 :    (GLN11)   (CYS72)   [view usage] : c.26.2.1 |Adenine nucleotide alpha hydrolase-like |Adenine nucleotide alpha hydrolases-like |N-type ATP pyrophosphatases |Argininosuccinate synthetase, N-terminal domain |Escherichia coli [TaxId: 562]
 d1rlua1 :    (VAL10)   (ASP57)   [view usage] : c.32.1.1 |Tubulin nucleotide-binding domain-like |Tubulin nucleotide-binding domain-like |Tubulin, GTPase domain |Cell-division protein FtsZ |Mycobacterium tuberculosis [TaxId: 1773]
 d2x0ia1 :    (MET22)   (GLY81)   [view usage] : c.2.1.5 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |LDH N-terminal domain-like |Malate dehydrogenase |Archaeoglobus fulgidus [TaxId: 2234]
 d1qnla_ :   (ASP199)  (ALA254)   [view usage] : c.93.1.1 |Periplasmic binding protein-like I |Periplasmic binding protein-like I |L-arabinose binding protein-like |Amide receptor/negative regulator of the amidase operon (AmiC) |Pseudomonas aeruginosa [TaxId: 287]
 d1peaa_ :   (ASP199)  (ALA254)   [view usage] : c.93.1.1 |Periplasmic binding protein-like I |Periplasmic binding protein-like I |L-arabinose binding protein-like |Amide receptor/negative regulator of the amidase operon (AmiC) |Pseudomonas aeruginosa [TaxId: 287]
 d3wgla1 :    (ALA12)   (GLY62)   [view usage] : c.32.1.1 |Tubulin nucleotide-binding domain-like |Tubulin nucleotide-binding domain-like |Tubulin, GTPase domain |Cell-division protein FtsZ |Staphylococcus aureus [TaxId: 158878]
 d3b9na_ :   (VAL223)  (GLY280)   [view usage] : c.1.16.0 |TIM beta/alpha-barrel |Bacterial luciferase-like |automated matches |automated matches |Geobacillus thermodenitrificans [TaxId: 33940]
 d1aoda_ :   (ASN199)  (ASP278)   [view usage] : c.1.18.2 |TIM beta/alpha-barrel |PLC-like phosphodiesterases |Bacterial PLC |Phosphatidylinositol-specific phospholipase C |Listeria monocytogenes [TaxId: 1639]
 d2cbna1 :    (ASP58)  (GLU120)   [view usage] : d.157.1.7 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |RNase Z-like |Ribonuclease Z (RNase Z) |Escherichia coli [TaxId: 562]
 d2b1la_ :    (LYS69)  (ASP129)   [view usage] : c.47.1.10 |Thioredoxin fold |Thioredoxin-like |Glutathione peroxidase-like |automated matches |Escherichia coli [TaxId: 562]
 d3nv8b_ :   (HIS277)  (ARG337)   [view usage] : c.1.10.8 |TIM beta/alpha-barrel |Aldolase |Class-II DAHP synthetase |Probable DAHP synthetase AroG, phenylalanine-repressible |Mycobacterium tuberculosis [TaxId: 1773]
 d2csua1 :    (ASP66)  (GLY126)   [view usage] : c.2.1.8 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |CoA-binding domain |Acetate-CoA ligase alpha chain, AcdA, N-terminal domain |Pyrococcus horikoshii [TaxId: 53953]
 d1o5ia_ :     (LYS8)   (ASP55)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |beta-keto acyl carrier protein reductase |Thermotoga maritima [TaxId: 2336]
 d3riha_ :    (ARG20)   (GLY73)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Mycobacterium abscessus [TaxId: 561007]
 d1peua2 :   (PHE179)  (HIS260)   [view usage] : c.7.1.2 |PFL-like glycyl radical enzymes |PFL-like glycyl radical enzymes |R1 subunit of ribonucleotide reductase, C-terminal domain |R1 subunit of ribonucleotide reductase, C-terminal domain |Salmonella typhimurium [TaxId: 90371]
 d2d0oa1 :   (TYR131)  (ASP183)   [view usage] : c.8.6.1 |The "swivelling" beta/beta/alpha domain |Swiveling domain of dehydratase reactivase alpha subunit |Swiveling domain of dehydratase reactivase alpha subunit |Diol dehydratase-reactivating factor large subunit DdrA |Klebsiella oxytoca [TaxId: 571]
 d1bhsa_ :     (VAL4)   (ARG67)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |Human estrogenic 17beta-hydroxysteroid dehydrogenase |Human (Homo sapiens) [TaxId: 9606]
 d3gvha1 :     (ASN4)   (ALA63)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Brucella melitensis [TaxId: 359391]
 d1yzhb_ :    (PRO40)   (TRP94)   [view usage] : c.66.1.53 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |TrmB-like |tRNA (guanine-N(7)-)-methyltransferase TrmB |Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]
 d1ml1a_ :     (GLN5)   (ALA64)   [view usage] : c.1.1.1 |TIM beta/alpha-barrel |Triosephosphate isomerase (TIM) |Triosephosphate isomerase (TIM) |Triosephosphate isomerase |Trypanosome (Trypanosoma brucei) [TaxId: 5691]
 d1v6za2 :    (VAL71)  (LEU141)   [view usage] : c.116.1.5 |alpha/beta knot |alpha/beta knot |YggJ C-terminal domain-like |Hypothetical protein TTHA0657 (TT1575) |Thermus thermophilus [TaxId: 274]
 d4hp8b_ :    (ARG10)   (ALA66)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Agrobacterium tumefaciens [TaxId: 176299]
 d1d2ia_ :    (ASP89)  (LEU170)   [view usage] : c.52.1.5 |Restriction endonuclease-like |Restriction endonuclease-like |Restriction endonuclease BglII |Restriction endonuclease BglII |Bacillus subtilis [TaxId: 1423]
 d1yzha1 :    (PRO40)   (TRP94)   [view usage] : c.66.1.53 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |TrmB-like |tRNA (guanine-N(7)-)-methyltransferase TrmB |Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]
 d1nbwa1 :   (GLU131)  (ASP185)   [view usage] : c.8.6.1 |The "swivelling" beta/beta/alpha domain |Swiveling domain of dehydratase reactivase alpha subunit |Swiveling domain of dehydratase reactivase alpha subunit |Swiveling domain of the glycerol dehydratase reactivase alpha subunit |Klebsiella pneumoniae [TaxId: 573]
 d4egfa_ :    (ALA19)   (ILE73)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Mycobacterium smegmatis [TaxId: 246196]
 d4hp8a_ :    (ARG10)   (ALA66)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Agrobacterium tumefaciens [TaxId: 176299]
 d1a2oa2 :   (LYS157)  (GLU213)   [view usage] : c.40.1.1 |Methylesterase CheB, C-terminal domain |Methylesterase CheB, C-terminal domain |Methylesterase CheB, C-terminal domain |Methylesterase CheB, C-terminal domain |Salmonella typhimurium [TaxId: 90371]
 d1yqga2 :     (MSE1)   (ALA50)   [view usage] : c.2.1.6 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |6-phosphogluconate dehydrogenase-like, N-terminal domain |Pyrroline-5-carboxylate reductase ProC |Neisseria meningitidis, serogroup B [TaxId: 487]
 d1v6aa1 :    (ASN21)   (ASP80)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Carp (Cyprinus carpio) [TaxId: 7962]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
   c.1,     c.2,    c.68,    c.26,   d.157,    c.66,    c.93,    c.37,     c.7,    c.47,    c.87,    c.32,     c.8,   c.116,    c.61,    c.52,   d.136,    c.70,    c.40