Protein Concepts Dictionary

Tableau information

Concept source:  d4kuxa_  amino acid (a.a.) range (HIS20)(MET90)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: HHHH

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	   (HIS20)   (GLU25) H1
	   (GLU25)   (GLN36) H2
	   (GLU43)   (PHE62) H3
	   (LEU66)   (MET90) H4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                          
H2      -47.4°   H2                   
H3      156.3°  140.4°   H3            
H4      -69.8°  -42.8°  132.8°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±13.0°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d2ps4b_ :    (THR28)  (SER102)   [view usage] : a.128.1.5 |Terpenoid synthases |Terpenoid synthases |Trichodiene synthase |Trichodiene synthase |Fusarium sporotrichioides [TaxId: 5514]
 d1kplb_ :   (GLY387)  (GLY440)   [view usage] : f.20.1.1 |Clc chloride channel |Clc chloride channel |Clc chloride channel |Clc chloride channel |Salmonella typhimurium [TaxId: 90371]
 d1hf0a1 :   (THR110)  (ARG158)   [view usage] : a.4.1.1 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |Homeodomain |Oct-1 POU Homeodomain |Human (Homo sapiens) [TaxId: 9606]
 d2p06b1 :     (MSE1)   (SER82)   [view usage] : a.204.1.3 |all-alpha NTP pyrophosphatases |all-alpha NTP pyrophosphatases |AF0060-like |Hypothetical protein AF0060 |Archaeoglobus fulgidus [TaxId: 2234]
 d1p7ia_ :    (SER10)   (LYS55)   [view usage] : a.4.1.1 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |Homeodomain |Engrailed Homeodomain |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d1p7jb_ :     (SER9)   (LYS55)   [view usage] : a.4.1.1 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |Homeodomain |Engrailed Homeodomain |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d3a01a_ :   (THR193)  (GLU246)   [view usage] : a.4.1.1 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |Homeodomain |automated matches |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d1oaia_ :   (SER564)  (GLY610)   [view usage] : a.5.2.3 |RuvA C-terminal domain-like |UBA-like |TAP-C domain-like |FG-binding, C-terminal domain of TAP |Human (Homo sapiens) [TaxId: 9606]
 d1af8a_ :    (ASP41)   (ALA86)   [view usage] : a.28.1.1 |Acyl carrier protein-like |ACP-like |Acyl-carrier protein (ACP) |Actinorhodin polyketide synthase acyl carrier protein, ACT ACP |Streptomyces coelicolor, A3(2) [TaxId: 1902]
 d4kuxa_ :    (HIS20)   (MET90)   [view usage] : a.128.1.4 |Terpenoid synthases |Terpenoid synthases |Aristolochene/pentalenene synthase |automated matches |Aspergillus terreus [TaxId: 33178]
 d3byia_ :   (PRO368)  (ALA420)   [view usage] : a.116.1.0 |GTPase activation domain, GAP |GTPase activation domain, GAP |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2h1rb_ :   (THR201)  (GLY272)   [view usage] : c.66.1.0 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |automated matches |automated matches |Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
 d1h3lb_ :    (SER28)  (TYR101)   [view usage] : a.177.1.1 |Sigma2 domain of RNA polymerase sigma factors |Sigma2 domain of RNA polymerase sigma factors |Sigma2 domain of RNA polymerase sigma factors |Sigma factor SigR |Streptomyces coelicolor A3(2) [TaxId: 100226]
 d1ocpa_ :    (LYS11)   (GLN61)   [view usage] : a.4.1.1 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |Homeodomain |Oct-3 POU Homeodomain |Mouse (Mus musculus) [TaxId: 10090]
 d1h3la_ :    (SER28)  (ARG102)   [view usage] : a.177.1.1 |Sigma2 domain of RNA polymerase sigma factors |Sigma2 domain of RNA polymerase sigma factors |Sigma2 domain of RNA polymerase sigma factors |Sigma factor SigR |Streptomyces coelicolor A3(2) [TaxId: 100226]
 d1ap4a_ :    (SER37)   (MET85)   [view usage] : a.39.1.5 |EF Hand-like |EF-hand |Calmodulin-like |Troponin C |Human (Homo sapiens), cardiac isoform [TaxId: 9606]
 d1bv2a_ :     (CYS3)   (GLY57)   [view usage] : a.52.1.1 |Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |Plant lipid-transfer and hydrophobic proteins |Plant non-specific lipid-transfer protein (ns-LTP, ns-LTP1) |Rice (Oryza sativa) [TaxId: 4530]
 d1iufa2 :    (TYR79)  (LEU140)   [view usage] : a.4.1.7 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |Centromere-binding |Ars-binding protein 1, ABP1 |Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896]
 d2q9zb_ :    (THR28)  (SER102)   [view usage] : a.128.1.5 |Terpenoid synthases |Terpenoid synthases |Trichodiene synthase |Trichodiene synthase |Fusarium sporotrichioides [TaxId: 5514]
 d3zlga1 :    (ASP83)  (LEU134)   [view usage] : d.54.1.0 |Enolase N-terminal domain-like |Enolase N-terminal domain-like |automated matches |automated matches |Streptococcus pyogenes [TaxId: 286636]
 d2k40a_ :     (THR9)   (ARG58)   [view usage] : a.4.1.0 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1ttxa_ :    (ASP60)  (SER109)   [view usage] : a.39.1.4 |EF Hand-like |EF-hand |Parvalbumin |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2nzaa_ :   (GLY187)  (GLY245)   [view usage] : a.104.1.1 |Cytochrome P450 |Cytochrome P450 |Cytochrome P450 |automated matches |Streptomyces coelicolor [TaxId: 100226]
 d1iw7f3 :   (LEU192)  (ASP253)   [view usage] : a.177.1.1 |Sigma2 domain of RNA polymerase sigma factors |Sigma2 domain of RNA polymerase sigma factors |Sigma2 domain of RNA polymerase sigma factors |Sigma70 |Thermus thermophilus [TaxId: 274]
 d4i9oa_ :   (LYS589)  (CYS664)   [view usage] : a.12.1.1 |Kix domain of CBP (creb binding protein) |Kix domain of CBP (creb binding protein) |Kix domain of CBP (creb binding protein) |Kix domain of CBP (creb binding protein) |Mouse (Mus musculus) [TaxId: 10090]
 d1cpja_ :    (SER28)   (ARG85)   [view usage] : d.3.1.1 |Cysteine proteinases |Cysteine proteinases |Papain-like |(Pro)cathepsin B |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d2aeka_ :    (THR28)   (LEU99)   [view usage] : a.128.1.5 |Terpenoid synthases |Terpenoid synthases |Trichodiene synthase |Trichodiene synthase |Fusarium sporotrichioides [TaxId: 5514]
 d3i4ka1 :    (SER65)  (ASN123)   [view usage] : d.54.1.0 |Enolase N-terminal domain-like |Enolase N-terminal domain-like |automated matches |automated matches |Corynebacterium glutamicum [TaxId: 1718]
 d3rpha_ :   (ASN206)  (GLU276)   [view usage] : c.72.1.4 |Ribokinase-like |Ribokinase-like |YjeF C-terminal domain-like |automated matches |Bacillus subtilis [TaxId: 1423]
 d2w9ba1 :   (GLY187)  (ASP231)   [view usage] : e.8.1.7 |DNA/RNA polymerases |DNA/RNA polymerases |Lesion bypass DNA polymerase (Y-family), catalytic domain |automated matches |Sulfolobus solfataricus [TaxId: 273057]
 d1v4ra1 :    (TYR11)   (ALA53)   [view usage] : a.4.5.6 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |GntR-like transcriptional regulators |Transcriptional repressor TraR, N-terminal domain |Streptomyces sp. [TaxId: 1931]
 d4i15a_ :   (LEU641)  (VAL708)   [view usage] : a.211.1.0 |HD-domain/PDEase-like |HD-domain/PDEase-like |automated matches |automated matches |Trypanosome (Trypanosoma brucei) [TaxId: 5691]
 d2k9na2 :    (PRO58)  (HIS104)   [view usage] : a.4.1.0 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |automated matches |automated matches |Trichomonas vaginalis [TaxId: 5722]
 d1dp3a_ :    (ASP10)   (MET54)   [view usage] : a.55.1.2 |IHF-like DNA-binding proteins |IHF-like DNA-binding proteins |DNA-binding domain (fragment?) of the TraM protein |DNA-binding domain (fragment?) of the TraM protein |Escherichia coli [TaxId: 562]
 d1zq9a1 :   (THR237)  (GLY309)   [view usage] : c.66.1.24 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |rRNA adenine dimethylase-like |Probable dimethyladenosine transferase |Human (Homo sapiens) [TaxId: 9606]
 d1r5za_ :    (GLY78)  (THR158)   [view usage] : f.40.1.1 |V-type ATP synthase subunit C |V-type ATP synthase subunit C |V-type ATP synthase subunit C |V-type ATP synthase subunit C |Thermus thermophilus [TaxId: 274]
 d3ucwa_ :    (THR28)   (LYS77)   [view usage] : a.39.1.5 |EF Hand-like |EF-hand |Calmodulin-like |Calmodulin |Human (Homo sapiens) [TaxId: 9606]
 d1tp4a_ :   (LEU232)  (GLU286)   [view usage] : a.189.1.1 |XPC-binding domain |XPC-binding domain |XPC-binding domain |XPC-binding domain of Rad23 homolog A (Hhr23a) |Human (Homo sapiens) [TaxId: 9606]
 d2woea_ :   (ASN126)  (GLY180)   [view usage] : a.209.1.0 |ADP-ribosylglycohydrolase |ADP-ribosylglycohydrolase |automated matches |automated matches |Rhodospirillum rubrum [TaxId: 1085]
 d2alga_ :     (CYS3)   (VAL58)   [view usage] : a.52.1.1 |Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |Plant lipid-transfer and hydrophobic proteins |automated matches |Prunus persica [TaxId: 3760]
 d1veja1 :    (LEU23)   (LEU66)   [view usage] : a.5.2.1 |RuvA C-terminal domain-like |UBA-like |UBA domain |4931431F19Rik |Mouse (Mus musculus) [TaxId: 10090]
 d4lrsa2 :   (TYR295)  (GLY346)   [view usage] : a.5.7.0 |RuvA C-terminal domain-like |post-HMGL domain-like |automated matches |automated matches |Thermomonospora curvata [TaxId: 471852]
 d1v19a_ :   (PRO246)  (ALA291)   [view usage] : c.72.1.1 |Ribokinase-like |Ribokinase-like |Ribokinase-like |2-keto-3-deoxygluconate kinase |Thermus thermophilus [TaxId: 274]
 d1e3ha1 :   (ASP265)  (LYS337)   [view usage] : a.4.9.1 |DNA/RNA-binding 3-helical bundle |Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |Streptomyces antibioticus [TaxId: 1890]
 d1enha_ :     (SER9)   (ILE56)   [view usage] : a.4.1.1 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |Homeodomain |Engrailed Homeodomain |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d4e4fd1 :    (LEU41)   (ILE86)   [view usage] : d.54.1.0 |Enolase N-terminal domain-like |Enolase N-terminal domain-like |automated matches |automated matches |Pectobacterium carotovorum [TaxId: 561230]
 d2f6la1 :    (LEU39)  (ASN119)   [view usage] : a.130.1.4 |Chorismate mutase II |Chorismate mutase II |Secreted chorismate mutase-like |Secreted chorismate mutase |Mycobacterium tuberculosis [TaxId: 1773]
 d2woca_ :   (ASN126)  (GLY180)   [view usage] : a.209.1.0 |ADP-ribosylglycohydrolase |ADP-ribosylglycohydrolase |automated matches |automated matches |Rhodospirillum rubrum [TaxId: 1085]
 d3g9da_ :   (ASN126)  (GLY180)   [view usage] : a.209.1.0 |ADP-ribosylglycohydrolase |ADP-ribosylglycohydrolase |automated matches |automated matches |Azospirillum brasilense [TaxId: 192]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
   e.8,   a.104,   a.128,    c.66,   a.211,    c.72,    f.20,     d.3,     a.4,    a.39,    a.55,    d.54,   a.116,    a.28,   a.209,   a.130,    a.52,   a.204,   a.177,     a.5,  
a.12, f.40, a.189