Protein Concepts Dictionary

Tableau information

Concept source:  d3k3ea_  amino acid (a.a.) range (PRO190)(TYR246)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: HHHH

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (PRO190)  (LEU196) H1
	  (PRO208)  (GLY223) H2
	  (GLY223)  (SER229) H3
	  (ASN231)  (TYR246) H4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                          
H2      -68.6°   H2                   
H3       79.7°   62.2°   H3            
H4       69.1°  137.2°  115.6°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±13.0°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d4dnob_ :   (ASP158)  (ALA208)   [view usage] : c.69.1.0 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |automated matches |automated matches |Pseudomonas aeruginosa [TaxId: 208963]
 d4dnod_ :   (ASP158)  (ALA208)   [view usage] : c.69.1.0 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |automated matches |automated matches |Pseudomonas aeruginosa [TaxId: 208963]
 d1u00a1 :   (THR505)  (GLY575)   [view usage] : a.8.4.1 |immunoglobulin/albumin-binding domain-like |Heat shock protein 70kD (HSP70), C-terminal subdomain |Heat shock protein 70kD (HSP70), C-terminal subdomain |Chaperone protein hscA (Hsc66) |Escherichia coli [TaxId: 562]
 d3bjva_ :   (SER107)  (LYS149)   [view usage] : d.112.1.0 |Phoshotransferase/anion transport protein |Phoshotransferase/anion transport protein |automated matches |automated matches |Streptococcus mutans [TaxId: 210007]
 d4dhwa_ :   (VAL147)  (GLN192)   [view usage] : c.56.3.0 |Phosphorylase/hydrolase-like |Peptidyl-tRNA hydrolase-like |automated matches |automated matches |Pseudomonas aeruginosa [TaxId: 208964]
 d2vglm1 :    (SER97)  (ILE133)   [view usage] : d.110.4.2 |Profilin-like |SNARE-like |Clathrin coat assembly domain |Mu2 adaptin (clathrin coat assembly protein AP50) |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d1oofa_ :    (PRO78)  (GLU115)   [view usage] : a.39.2.1 |EF Hand-like |Insect pheromone/odorant-binding proteins |Insect pheromone/odorant-binding proteins |Odorant binding protein LUSH |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d4fyja_ :   (VAL147)  (GLN192)   [view usage] : c.56.3.0 |Phosphorylase/hydrolase-like |Peptidyl-tRNA hydrolase-like |automated matches |automated matches |Pseudomonas aeruginosa [TaxId: 208964]
 d2ezwa1 :    (SER12)   (GLU58)   [view usage] : a.31.1.1 |Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit |Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit |Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit |cAMP-dependent protein kinase type I-alpha regulatory subunit |Cow (Bos taurus) [TaxId: 9913]
 d1o7xb_ :   (GLY220)  (LYS250)   [view usage] : a.103.1.1 |Citrate synthase |Citrate synthase |Citrate synthase |Citrate synthase |Sulfolobus solfataricus [TaxId: 2287]
 d1aqea_ :    (GLU68)  (HIS109)   [view usage] : a.138.1.1 |Multiheme cytochromes |Multiheme cytochromes |Cytochrome c3-like |Cytochrome c3 |Desulfovibrio desulfuricans, different strains [TaxId: 876]
 d4bzsb_ :   (THR206)  (ILE264)   [view usage] : d.92.1.0 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1kywa2 :   (SER125)  (TYR158)   [view usage] : c.66.1.12 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |Plant O-methyltransferase, C-terminal domain |Caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase |Alfalfa (Medicago sativa) [TaxId: 3879]
 d3gxkd_ :    (SER17)   (SER71)   [view usage] : d.2.1.5 |Lysozyme-like |Lysozyme-like |G-type lysozyme |automated matches |Atlantic cod (Gadus morhua) [TaxId: 8049]
 d1o7xa_ :   (GLY220)  (LYS250)   [view usage] : a.103.1.1 |Citrate synthase |Citrate synthase |Citrate synthase |Citrate synthase |Sulfolobus solfataricus [TaxId: 2287]
 d1tw2b1 :    (ILE13)   (THR57)   [view usage] : a.4.5.29 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |Plant O-methyltransferase, N-terminal domain |Carminomycin 4-O-methyltransferase |Streptomyces peucetius [TaxId: 1950]
 d2qyoa2 :   (LEU116)  (ASN150)   [view usage] : c.66.1.12 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |Plant O-methyltransferase, C-terminal domain |automated matches |Medicago truncatula [TaxId: 3880]
 d3dysa_ :   (SER189)  (TYR246)   [view usage] : a.211.1.2 |HD-domain/PDEase-like |HD-domain/PDEase-like |PDEase |High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A |Human (Homo sapiens) [TaxId: 9606]
 d2hd1a_ :   (SER189)  (TYR246)   [view usage] : a.211.1.2 |HD-domain/PDEase-like |HD-domain/PDEase-like |PDEase |High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A |Human (Homo sapiens) [TaxId: 9606]
 d1iawa_ :    (GLU10)   (GLU76)   [view usage] : c.52.1.9 |Restriction endonuclease-like |Restriction endonuclease-like |Restriction endonuclease NaeI |Restriction endonuclease NaeI |Nocardia aerocolonigenes [TaxId: 68170]
 d1tw2b2 :   (GLN102)  (TYR137)   [view usage] : c.66.1.12 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |Plant O-methyltransferase, C-terminal domain |Carminomycin 4-O-methyltransferase |Streptomyces peucetius [TaxId: 1950]
 d2onkc1 :   (ALA127)  (VAL182)   [view usage] : f.58.1.1 |MetI-like |MetI-like |MetI-like |Molybdate/tungstate transport system permease protein WtpB (ModB) |Archaeoglobus fulgidus [TaxId: 2234]
 d1ux5a_ :  (TYR1538) (PRO1622)   [view usage] : a.207.1.1 |Formin homology 2 domain (FH2 domain) |Formin homology 2 domain (FH2 domain) |Formin homology 2 domain (FH2 domain) |Bni1 |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d3k3ea_ :   (PRO190)  (TYR246)   [view usage] : a.211.1.2 |HD-domain/PDEase-like |HD-domain/PDEase-like |PDEase |High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A |Human (Homo sapiens) [TaxId: 9606]
 d1zj8a4 :   (PRO262)  (LEU312)   [view usage] : d.134.1.1 |Nitrite and sulphite reductase 4Fe-4S domain-like |Nitrite and sulphite reductase 4Fe-4S domain-like |Nitrite and sulphite reductase 4Fe-4S domain-like |Sulfite reductase NirA |Mycobacterium tuberculosis [TaxId: 1773]
 d1wera_ :   (THR792)  (LEU866)   [view usage] : a.116.1.2 |GTPase activation domain, GAP |GTPase activation domain, GAP |p120GAP domain-like |p120GAP domain |Human (Homo sapiens) [TaxId: 9606]
 d2j3qa_ :   (SER228)  (ASP276)   [view usage] : c.69.1.1 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Acetylcholinesterase-like |Acetylcholinesterase |Pacific electric ray (Torpedo californica) [TaxId: 7787]
 d1mbza1 :   (GLY445)  (SER503)   [view usage] : c.26.2.1 |Adenine nucleotide alpha hydrolase-like |Adenine nucleotide alpha hydrolases-like |N-type ATP pyrophosphatases |beta-Lactam synthetase |Streptomyces clavuligerus [TaxId: 1901]
 d1czja_ :    (GLU68)  (HIS109)   [view usage] : a.138.1.1 |Multiheme cytochromes |Multiheme cytochromes |Cytochrome c3-like |Cytochrome c3 |Desulfomicrobium norvegicum [TaxId: 52561]
 d4lrlc_ :    (ASN96)  (THR138)   [view usage] : a.211.1.1 |HD-domain/PDEase-like |HD-domain/PDEase-like |HD domain |Hypothetical protein EF1143 |Enterococcus faecalis [TaxId: 1351]
 d1xm8a_ :   (THR210)  (ASP253)   [view usage] : d.157.1.2 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |Glyoxalase II (hydroxyacylglutathione hydrolase) |Glyoxalase II (hydroxyacylglutathione hydrolase) |Thale cress (Arabidopsis thaliana) [TaxId: 3702]
 d1ooha_ :    (PRO78)  (GLU115)   [view usage] : a.39.2.1 |EF Hand-like |Insect pheromone/odorant-binding proteins |Insect pheromone/odorant-binding proteins |Odorant binding protein LUSH |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d1p58d_ :    (SER21)   (THR75)   [view usage] : i.17.1.1 |Virus envelope proteins |Virus envelope proteins |Virus envelope proteins |Virus envelope proteins |Dengue virus [TaxId: 12637]
 d1zg3a2 :   (LEU119)  (ALA154)   [view usage] : c.66.1.0 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |automated matches |automated matches |Medicago truncatula [TaxId: 3880]
 d1m56a_ :    (GLY15)   (PRO82)   [view usage] : f.24.1.1 |Cytochrome c oxidase subunit I-like |Cytochrome c oxidase subunit I-like |Cytochrome c oxidase subunit I-like |Bacterial aa3 type cytochrome c oxidase subunit I |Rhodobacter sphaeroides [TaxId: 1063]
 d1ej2a_ :   (TYR126)  (ALA170)   [view usage] : c.26.1.3 |Adenine nucleotide alpha hydrolase-like |Nucleotidylyl transferase |Adenylyltransferase |Nicotinamide mononucleotide (NMN) adenylyltransferase |Methanobacterium thermoautotrophicum [TaxId: 145262]
 d3h0uc_ :   (PRO233)  (LEU281)   [view usage] : c.14.1.0 |ClpP/crotonase |ClpP/crotonase |automated matches |automated matches |Streptomyces avermitilis [TaxId: 33903]
 d4pgga2 :   (MET121)  (TYR155)   [view usage] : c.66.1.0 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |automated matches |automated matches |Sorghum (Sorghum bicolor) [TaxId: 4558]
 d2qeda1 :   (LEU207)  (PHE251)   [view usage] : d.157.1.2 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |Glyoxalase II (hydroxyacylglutathione hydrolase) |Glyoxalase II (hydroxyacylglutathione hydrolase) |Salmonella typhimurium [TaxId: 90371]
 d1gpqb_ :   (ASN100)  (ASN127)   [view usage] : d.233.1.1 |Inhibitor of vertebrate lysozyme, Ivy |Inhibitor of vertebrate lysozyme, Ivy |Inhibitor of vertebrate lysozyme, Ivy |Inhibitor of vertebrate lysozyme, Ivy |Escherichia coli [TaxId: 562]
 d3reoa2 :   (LEU127)  (TYR161)   [view usage] : c.66.1.12 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |Plant O-methyltransferase, C-terminal domain |automated matches |Clarkia breweri [TaxId: 36903]
 d4be8a_ :   (PHE740)  (GLY778)   [view usage] : d.148.1.0 |Hect, E3 ligase catalytic domain |Hect, E3 ligase catalytic domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1f6wa_ :   (SER225)  (LEU268)   [view usage] : c.69.1.1 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Acetylcholinesterase-like |Bile-salt activated lipase (cholesterol esterase) |Human (Homo sapiens) [TaxId: 9606]
 d2vn0a_ :   (PRO220)  (THR299)   [view usage] : a.104.1.1 |Cytochrome P450 |Cytochrome P450 |Cytochrome P450 |Mammalian cytochrome p450 2c8 |Human (Homo sapiens) [TaxId: 9606]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  c.69,   a.104,    c.26,    c.56,   d.157,    c.66,    d.92,    c.14,   a.211,   a.103,     d.2,   d.110,    f.24,   d.134,    c.52,     a.4,    a.39,   a.138,   d.148,   a.116,  
d.112, i.17, a.8, f.58, d.233, a.207, a.31