Protein Concepts Dictionary

Tableau information

Concept source:  d3hu2a3  amino acid (a.a.) range (ASP373)(ASP434)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: HHHH

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (ASP373)  (MET388) H1
	  (GLU397)  (THR403) H2
	  (GLY408)  (MET427) H3
	  (ASP431)  (ASP434) H4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                          
H2      129.1°   H2                   
H3      -42.9°  121.5°   H3            
H4       74.1° -106.3°  115.6°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±13.0°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d2qi9c_ :    (PRO89)  (GLY152)   [view usage] : c.37.1.12 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |ABC transporter ATPase domain-like |ABC transporter involved in vitamin B12 uptake, BtuD |Escherichia coli [TaxId: 562]
 d1frfl_ :   (ASP137)  (THR244)   [view usage] : e.18.1.1 |HydB/Nqo4-like |HydB/Nqo4-like |Nickel-iron hydrogenase, large subunit |Nickel-iron hydrogenase, large subunit |Desulfovibrio fructosovorans [TaxId: 878]
 d153la_ :   (ALA146)  (GLY184)   [view usage] : d.2.1.5 |Lysozyme-like |Lysozyme-like |G-type lysozyme |Lysozyme |Western graylag goose (Anser anser anser) [TaxId: 8844]
 d1wvua_ :   (ASN158)  (TRP228)   [view usage] : d.2.1.0 |Lysozyme-like |Lysozyme-like |automated matches |automated matches |Streptomyces griseus [TaxId: 1911]
 d1djgb1 :   (PHE162)  (ALA222)   [view usage] : a.39.1.7 |EF Hand-like |EF-hand |EF-hand modules in multidomain proteins |Phosphoinositide-specific phospholipase C, isozyme D1 (PLC-D!) |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d1ty4b_ :    (GLU75)  (VAL141)   [view usage] : f.1.4.1 |Toxins' membrane translocation domains |Bcl-2 inhibitors of programmed cell death |Bcl-2 inhibitors of programmed cell death |Apoptosis regulator ced-9 |Nematode (Caenorhabditis elegans) [TaxId: 6239]
 d1or7c_ :     (GLN2)   (GLU66)   [view usage] : a.180.1.1 |N-terminal, cytoplasmic domain of anti-sigmaE factor RseA |N-terminal, cytoplasmic domain of anti-sigmaE factor RseA |N-terminal, cytoplasmic domain of anti-sigmaE factor RseA |N-terminal, cytoplasmic domain of anti-sigmaE factor RseA |Escherichia coli [TaxId: 562]
 d3nmaa_ :   (VAL427)  (ALA474)   [view usage] : e.8.1.4 |DNA/RNA polymerases |DNA/RNA polymerases |RNA-dependent RNA-polymerase |Viral RNA polymerase |Foot-and-mouth disease virus - type c [TaxId: 12116]
 d2m34a_ :    (THR15)   (SER71)   [view usage] : a.4.1.0 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2isga_ :   (SER259)  (LYS320)   [view usage] : d.92.1.7 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Clostridium neurotoxins, catalytic domain |automated matches |Clostridium botulinum [TaxId: 1491]
 d4icgc_ :     (LYS8)   (PHE70)   [view usage] : a.23.5.1 |Open three-helical up-and-down bundle |Hemolysin expression modulating protein HHA |Hemolysin expression modulating protein HHA |automated matches |Salmonella enterica [TaxId: 990282]
 d2cwqa1 :    (ASP53)  (LEU117)   [view usage] : a.152.1.4 |AhpD-like |AhpD-like |TTHA0727-like |Hypothetical protein TTHA0727 |Thermus thermophilus [TaxId: 274]
 d3j38r_ :     (THR6)   (ASP82)   [view usage] : i.1.1.1 |Ribosome and ribosomal fragments |Ribosome and ribosomal fragments |Ribosome complexes |Eukaryotic, cytoplasmic (80S ribosome functional complex) |Drosophila melanogaster [TaxId: 7227]
 d1oipa1 :    (LEU28)   (ASP86)   [view usage] : a.5.3.1 |RuvA C-terminal domain-like |CRAL/TRIO N-terminal domain |CRAL/TRIO N-terminal domain |Alpha-tocopherol transfer protein |Human (Homo sapiens) [TaxId: 9606]
 d2rdxa1 :    (GLY64)  (GLY126)   [view usage] : d.54.1.0 |Enolase N-terminal domain-like |Enolase N-terminal domain-like |automated matches |automated matches |Roseovarius nubinhibens [TaxId: 89187]
 d2dbta_ :   (ASN161)  (TRP228)   [view usage] : d.2.1.0 |Lysozyme-like |Lysozyme-like |automated matches |automated matches |Streptomyces griseus [TaxId: 1911]
 d1ddxa1 :   (ASN537)  (VAL572)   [view usage] : a.93.1.2 |Heme-dependent peroxidases |Heme-dependent peroxidases |Myeloperoxidase-like |Prostaglandin H2 synthase |Mouse (Mus musculus) [TaxId: 10090]
 d1c52a_ :     (ASP3)   (LEU51)   [view usage] : a.3.1.1 |Cytochrome c |Cytochrome c |monodomain cytochrome c |Cytochrome c552 |Thermus thermophilus [TaxId: 274]
 d1sana_ :     (THR9)   (GLY67)   [view usage] : a.4.1.1 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |Homeodomain |Antennapedia Homeodomain |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d3klva_ :   (GLN421)  (HIS476)   [view usage] : e.8.1.4 |DNA/RNA polymerases |DNA/RNA polymerases |RNA-dependent RNA-polymerase |Viral RNA polymerase |Foot-and-mouth disease virus - type c [TaxId: 12116]
 d1b4ua_ :    (TYR79)  (GLY125)   [view usage] : a.88.1.1 |LigA subunit of an aromatic-ring-opening dioxygenase LigAB |LigA subunit of an aromatic-ring-opening dioxygenase LigAB |LigA subunit of an aromatic-ring-opening dioxygenase LigAB |LigA subunit of an aromatic-ring-opening dioxygenase LigAB |Sphingomonas paucimobilis, formerly Pseudomonas paucimobilis [TaxId: 13689]
 d3j6vj_ :     (ARG4)   (ILE65)   [view usage] : i.1.1.3 |Ribosome and ribosomal fragments |Ribosome and ribosomal fragments |Small subunit |Eukaryotic, mitochondrial (28S subunit) |Cow (Bos taurus) [TaxId: 9913]
 d1u09a_ :   (GLN421)  (HIS476)   [view usage] : e.8.1.4 |DNA/RNA polymerases |DNA/RNA polymerases |RNA-dependent RNA-polymerase |Viral RNA polymerase |Foot-and-mouth disease virus [TaxId: 12110]
 d2cjla_ :    (ASN79)  (TRP149)   [view usage] : d.2.1.0 |Lysozyme-like |Lysozyme-like |automated matches |automated matches |Streptomyces coelicolor [TaxId: 1902]
 d1hdpa_ :    (VAL12)   (SER63)   [view usage] : a.4.1.1 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |Homeodomain |Oct-2 POU Homeodomain |Human (Homo sapiens) [TaxId: 9606]
 d2k5sa_ :     (LYS3)   (HIS65)   [view usage] : a.23.5.1 |Open three-helical up-and-down bundle |Hemolysin expression modulating protein HHA |Hemolysin expression modulating protein HHA |automated matches |Yersinia pestis [TaxId: 632]
 d1jw2a_ :     (THR7)   (ILE71)   [view usage] : a.23.5.1 |Open three-helical up-and-down bundle |Hemolysin expression modulating protein HHA |Hemolysin expression modulating protein HHA |Hemolysin expression modulating protein HHA |Escherichia coli [TaxId: 562]
 d2cwqc_ :    (ASP53)  (LEU117)   [view usage] : a.152.1.4 |AhpD-like |AhpD-like |TTHA0727-like |Hypothetical protein TTHA0727 |Thermus thermophilus [TaxId: 274]
 d3q45a1 :    (SER58)  (GLY123)   [view usage] : d.54.1.0 |Enolase N-terminal domain-like |Enolase N-terminal domain-like |automated matches |automated matches |Cytophaga hutchinsonii [TaxId: 269798]
 d2c52a_ :     (SER7)   (GLN56)   [view usage] : a.153.1.1 |Nuclear receptor coactivator interlocking domain |Nuclear receptor coactivator interlocking domain |Nuclear receptor coactivator interlocking domain |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d2p1pa2 :    (PHE99)  (GLU160)   [view usage] : a.157.1.0 |Skp1 dimerisation domain-like |Skp1 dimerisation domain-like |automated matches |automated matches |Thale cress (Arabidopsis thaliana) [TaxId: 3702]
 d1rj1a_ :     (ASN2)   (LYS67)   [view usage] : a.29.6.1 |Bromodomain-like |Plant invertase/pectin methylesterase inhibitor |Plant invertase/pectin methylesterase inhibitor |Invertase inhibitor |Tobacco (Nicotiana tabacum) [TaxId: 4097]
 d4icgd_ :     (LYS8)   (PHE70)   [view usage] : a.23.5.1 |Open three-helical up-and-down bundle |Hemolysin expression modulating protein HHA |Hemolysin expression modulating protein HHA |automated matches |Salmonella enterica [TaxId: 990282]
 d1kqqa_ :     (GLU7)   (LYS75)   [view usage] : a.4.3.1 |DNA/RNA-binding 3-helical bundle |ARID-like |ARID domain |DNA-binding domain from the dead ringer protein |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d3zq7a_ :    (THR52)   (ILE94)   [view usage] : a.4.6.0 |DNA/RNA-binding 3-helical bundle |C-terminal effector domain of the bipartite response regulators |automated matches |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d2cwqb_ :    (ASP53)  (LEU117)   [view usage] : a.152.1.4 |AhpD-like |AhpD-like |TTHA0727-like |Hypothetical protein TTHA0727 |Thermus thermophilus [TaxId: 274]
 d3knaa_ :   (THR419)  (GLU474)   [view usage] : e.8.1.4 |DNA/RNA polymerases |DNA/RNA polymerases |RNA-dependent RNA-polymerase |Viral RNA polymerase |Foot-and-mouth disease virus - type c [TaxId: 12116]
 d3curh_ :   (PRO138)  (THR244)   [view usage] : e.18.1.1 |HydB/Nqo4-like |HydB/Nqo4-like |Nickel-iron hydrogenase, large subunit |automated matches |Desulfovibrio fructosovorans [TaxId: 878]
 d1or7f_ :     (GLN2)   (GLU64)   [view usage] : a.180.1.1 |N-terminal, cytoplasmic domain of anti-sigmaE factor RseA |N-terminal, cytoplasmic domain of anti-sigmaE factor RseA |N-terminal, cytoplasmic domain of anti-sigmaE factor RseA |N-terminal, cytoplasmic domain of anti-sigmaE factor RseA |Escherichia coli [TaxId: 562]
 d3w67c1 :    (GLY27)   (ASP86)   [view usage] : a.5.3.0 |RuvA C-terminal domain-like |CRAL/TRIO N-terminal domain |automated matches |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d2d7sa1 :   (GLN421)  (GLU474)   [view usage] : e.8.1.4 |DNA/RNA polymerases |DNA/RNA polymerases |RNA-dependent RNA-polymerase |Viral RNA polymerase |Foot-and-mouth disease virus [TaxId: 12110]
 d2kk0a_ :    (LYS24)   (LYS86)   [view usage] : a.4.3.1 |DNA/RNA-binding 3-helical bundle |ARID-like |ARID domain |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1efub3 :     (THR4)   (ASN54)   [view usage] : a.5.2.2 |RuvA C-terminal domain-like |UBA-like |TS-N domain |Elongation factor Ts (EF-Ts), N-terminal domain |Escherichia coli [TaxId: 562]
 d1opca_ :   (SER181)  (GLN223)   [view usage] : a.4.6.1 |DNA/RNA-binding 3-helical bundle |C-terminal effector domain of the bipartite response regulators |PhoB-like |OmpR |Escherichia coli [TaxId: 562]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
   e.8,     i.1,    d.92,    a.93,    e.18,    c.37,     d.2,   a.152,     a.4,    a.39,     a.3,    a.29,     f.1,    a.23,    d.54,   a.157,     a.5,   a.153,   a.180,    a.88