Protein Concepts Dictionary

Tableau information

Concept source:  d1b4fa_  amino acid (a.a.) range (TYR26)(SER79)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: HHHH

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	   (TYR26)   (GLY34) H1
	   (SER37)   (MET44) H2
	   (MET46)   (VAL52) H3
	   (LEU56)   (SER79) H4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                          
H2      103.6°   H2                   
H3      110.7° -111.5°   H3            
H4      -60.4° -119.0°  129.4°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±13.0°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d2wu2c_ :    (ILE22)  (VAL128)   [view usage] : f.21.2.2 |Heme-binding four-helical bundle |Fumarate reductase respiratory complex transmembrane subunits |Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) |Succinate dehydrogenase subunit SdhC |Escherichia coli [TaxId: 562]
 d2jrza_ :    (LEU42)   (ILE90)   [view usage] : a.4.3.0 |DNA/RNA-binding 3-helical bundle |ARID-like |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d3ntua1 :    (PRO13)   (ASP61)   [view usage] : a.60.4.1 |SAM domain-like |Rad51 N-terminal domain-like |DNA repair protein Rad51, N-terminal domain |DNA repair protein Rad51, N-terminal domain |Methanococcus voltae [TaxId: 523842]
 d2f1ha1 :    (GLY12)   (ASP61)   [view usage] : a.60.4.0 |SAM domain-like |Rad51 N-terminal domain-like |automated matches |automated matches |Methanococcus voltae [TaxId: 2188]
 d1yona1 :   (ILE169)  (THR238)   [view usage] : a.100.1.7 |6-phosphogluconate dehydrogenase C-terminal domain-like |6-phosphogluconate dehydrogenase C-terminal domain-like |Ketopantoate reductase PanE |Ketopantoate reductase PanE |Escherichia coli [TaxId: 562]
 d1j1va_ :   (THR375)  (PHE429)   [view usage] : a.4.12.2 |DNA/RNA-binding 3-helical bundle |TrpR-like |Chromosomal replication initiation factor DnaA C-terminal domain IV |Chromosomal replication initiation factor DnaA C-terminal domain IV |Escherichia coli [TaxId: 562]
 d2reqa1 :   (SER486)  (LEU552)   [view usage] : c.1.19.1 |TIM beta/alpha-barrel |Cobalamin (vitamin B12)-dependent enzymes |Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain |Methylmalonyl-CoA mutase alpha subunit, domain 1 |Propionibacterium freudenreichii, subsp. shermanii [TaxId: 1744]
 d1lzwb_ :    (ASN94)  (THR157)   [view usage] : a.174.1.1 |Double Clp-N motif |Double Clp-N motif |Double Clp-N motif |N-terminal, ClpS-binding domain of ClpA, an Hsp100 chaperone |Escherichia coli [TaxId: 562]
 d3etla1 :    (PRO13)   (ASP61)   [view usage] : a.60.4.0 |SAM domain-like |Rad51 N-terminal domain-like |automated matches |automated matches |Methanococcus maripaludis [TaxId: 39152]
 d2doda1 :   (PRO658)  (ARG719)   [view usage] : a.159.2.1 |Another 3-helical bundle |FF domain |FF domain |Transcription elongation regulator 1 |Human (Homo sapiens) [TaxId: 9606]
 d2o3ea_ :   (ASP467)  (ARG544)   [view usage] : d.92.1.5 |Zincin-like |Metalloproteases ("zincins"), catalytic domain |Neurolysin-like |automated matches |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d1uzca_ :    (THR13)   (GLU70)   [view usage] : a.159.2.1 |Another 3-helical bundle |FF domain |FF domain |Hypa/FBP11 |Human (Homo sapiens) [TaxId: 9606]
 d3jpza1 :    (CYS19)   (ASN54)   [view usage] : a.83.1.0 |Guanido kinase N-terminal domain |Guanido kinase N-terminal domain |automated matches |automated matches |Innkeeper worm (Urechis caupo) [TaxId: 6431]
 d2zmea1 :    (ALA34)   (MET90)   [view usage] : a.4.5.0 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2i4ka_ :    (ARG45)  (GLU122)   [view usage] : d.189.1.0 |PX domain |PX domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1wjba_ :     (LEU2)   (CYS40)   [view usage] : a.4.10.1 |DNA/RNA-binding 3-helical bundle |N-terminal Zn binding domain of HIV integrase |N-terminal Zn binding domain of HIV integrase |N-terminal Zn binding domain of HIV integrase |Human immunodeficiency virus type 1 [TaxId: 11676]
 d1vfga1 :   (VAL144)  (ALA187)   [view usage] : a.173.1.1 |Poly A polymerase C-terminal region-like |Poly A polymerase C-terminal region-like |Poly A polymerase C-terminal region-like |Poly A polymerase PcnB |Aquifex aeolicus [TaxId: 63363]
 d1j3xa_ :    (SER15)   (MET75)   [view usage] : a.21.1.1 |HMG-box |HMG-box |HMG-box |High mobility group protein 2, HMG2 |Pig (Sus scrofa) [TaxId: 9823]
 d2eaoa_ :    (TYR37)   (GLN84)   [view usage] : a.60.1.0 |SAM domain-like |SAM/Pointed domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1qzwa2 :   (GLU372)  (MET430)   [view usage] : a.36.1.1 |Signal peptide-binding domain |Signal peptide-binding domain |Signal peptide-binding domain |Signal sequence binding protein Ffh |Sulfolobus solfataricus [TaxId: 2287]
 d4mhvb_ :   (ASN128)  (LYS168)   [view usage] : a.60.1.0 |SAM domain-like |SAM/Pointed domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2cqna1 :   (MET743)  (GLN805)   [view usage] : a.159.2.1 |Another 3-helical bundle |FF domain |FF domain |Hypa/FBP11 |Human (Homo sapiens) [TaxId: 9606]
 d1kzma_ :    (ASN13)  (GLY113)   [view usage] : a.93.1.1 |Heme-dependent peroxidases |Heme-dependent peroxidases |CCP-like |Plant peroxidase |Horseradish (Armoracia rusticana) [TaxId: 3704]
 d1r6bx1 :     (ASN3)   (THR66)   [view usage] : a.174.1.1 |Double Clp-N motif |Double Clp-N motif |Double Clp-N motif |N-terminal, ClpS-binding domain of ClpA, an Hsp100 chaperone |Escherichia coli [TaxId: 562]
 d1yjqa1 :   (ILE169)  (THR238)   [view usage] : a.100.1.7 |6-phosphogluconate dehydrogenase C-terminal domain-like |6-phosphogluconate dehydrogenase C-terminal domain-like |Ketopantoate reductase PanE |Ketopantoate reductase PanE |Escherichia coli [TaxId: 562]
 d3gfkb_ :   (SER259)  (GLY307)   [view usage] : a.60.3.1 |SAM domain-like |C-terminal domain of RNA polymerase alpha subunit |C-terminal domain of RNA polymerase alpha subunit |automated matches |Bacillus subtilis [TaxId: 1423]
 d4m9ab1 :     (THR6)   (CYS80)   [view usage] : e.6.1.0 |Acyl-CoA dehydrogenase NM domain-like |Acyl-CoA dehydrogenase NM domain-like |automated matches |automated matches |Burkholderia thailandensis [TaxId: 271848]
 d1s7ea1 :   (ASP109)  (PHE147)   [view usage] : a.4.1.1 |DNA/RNA-binding 3-helical bundle |Homeodomain-like |Homeodomain |Hepatocyte nuclear factor 6 |Mouse (Mus musculus) [TaxId: 10090]
 d1xg7b_ :    (ILE97)  (ALA160)   [view usage] : a.96.1.6 |DNA-glycosylase |DNA-glycosylase |AgoG-like |Hypothetical protein PF0904 |Pyrococcus furiosus [TaxId: 2261]
 d2dvha_ :     (GLY3)   (LEU79)   [view usage] : a.3.1.1 |Cytochrome c |Cytochrome c |monodomain cytochrome c |Cytochrome c6 (synonym: cytochrome c553) |Desulfovibrio desulfuricans [TaxId: 876]
 d1ucva_ :    (MET19)   (LEU70)   [view usage] : a.60.1.2 |SAM domain-like |SAM/Pointed domain |SAM (sterile alpha motif) domain |Ephrin type-A receptor 8, C-terminal domain |Human (Homo sapiens) [TaxId: 9606]
 d1c3qa1 :   (HIS187)  (SER253)   [view usage] : c.72.1.2 |Ribokinase-like |Ribokinase-like |Thiamin biosynthesis kinases |Hydroxyethylthiazole kinase (THZ kinase, ThiK) |Bacillus subtilis [TaxId: 1423]
 d2wdqc_ :    (ILE22)  (VAL128)   [view usage] : f.21.2.2 |Heme-binding four-helical bundle |Fumarate reductase respiratory complex transmembrane subunits |Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) |Succinate dehydrogenase subunit SdhC |Escherichia coli [TaxId: 562]
 d1s9hb_ :   (GLY224)  (LYS278)   [view usage] : c.37.1.20 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |Extended AAA-ATPase domain |Rep 40 protein helicase domain |Adeno-associated virus 2, AAV2 [TaxId: 10804]
 d1nq4a_ :     (THR5)   (GLY38)   [view usage] : a.28.1.1 |Acyl carrier protein-like |ACP-like |Acyl-carrier protein (ACP) |Oxytetracycline polyketide synthase acyl carrier |Streptomyces rimosus [TaxId: 1927]
 d2eqza_ :    (ALA22)   (GLY86)   [view usage] : a.21.1.1 |HMG-box |HMG-box |HMG-box |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d4fl4j_ :    (ASP24)   (ARG81)   [view usage] : a.139.1.0 |Type I dockerin domain |Type I dockerin domain |automated matches |automated matches |Clostridium thermocellum [TaxId: 1515]
 d2jv3a_ :    (ASP94)  (LYS134)   [view usage] : a.60.1.1 |SAM domain-like |SAM/Pointed domain |Pointed domain |Ets-1 transcription factor pointed domain |Mouse (Mus musculus) [TaxId: 10090]
 d1xg7a_ :    (LEU96)  (ALA160)   [view usage] : a.96.1.6 |DNA-glycosylase |DNA-glycosylase |AgoG-like |Hypothetical protein PF0904 |Pyrococcus furiosus [TaxId: 2261]
 d1y88a1 :   (ASP136)  (GLY184)   [view usage] : a.60.4.3 |SAM domain-like |Rad51 N-terminal domain-like |Hypothetical protein AF1548, C-terminal domain |Hypothetical protein AF1548, C-terminal domain |Archaeoglobus fulgidus [TaxId: 2234]
 d1s9ha_ :   (LEU227)  (LYS278)   [view usage] : c.37.1.20 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |Extended AAA-ATPase domain |Rep 40 protein helicase domain |Adeno-associated virus 2, AAV2 [TaxId: 10804]
 d2gfnb2 :    (PRO83)  (ALA173)   [view usage] : a.121.1.1 |Tetracyclin repressor-like, C-terminal domain |Tetracyclin repressor-like, C-terminal domain |Tetracyclin repressor-like, C-terminal domain |Probable transcriptional regulator RHA1_ro04631 |Rhodococcus sp. RHA1 [TaxId: 101510]
 d1t4ga1 :    (PRO13)   (ASP61)   [view usage] : a.60.4.1 |SAM domain-like |Rad51 N-terminal domain-like |DNA repair protein Rad51, N-terminal domain |DNA repair protein Rad51, N-terminal domain |Methanococcus voltae [TaxId: 2188]
 d3hzsa_ :   (THR212)  (ASN268)   [view usage] : d.2.1.0 |Lysozyme-like |Lysozyme-like |automated matches |automated matches |Staphylococcus aureus [TaxId: 196620]
 d1ks9a1 :   (ILE169)  (THR238)   [view usage] : a.100.1.7 |6-phosphogluconate dehydrogenase C-terminal domain-like |6-phosphogluconate dehydrogenase C-terminal domain-like |Ketopantoate reductase PanE |Ketopantoate reductase PanE |Escherichia coli [TaxId: 562]
 d2b7ea1 :     (GLU4)   (ASN58)   [view usage] : a.159.2.1 |Another 3-helical bundle |FF domain |FF domain |Pre-mRNA-processing protein PRP40 |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d2ffha2 :   (ASP355)  (LYS418)   [view usage] : a.36.1.1 |Signal peptide-binding domain |Signal peptide-binding domain |Signal peptide-binding domain |Signal sequence binding protein Ffh |Thermus aquaticus [TaxId: 271]
 d2haja_ :   (MET451)  (TRP522)   [view usage] : a.236.1.1 |DNA primase DnaG, C-terminal domain |DNA primase DnaG, C-terminal domain |DNA primase DnaG, C-terminal domain |DNA primase DnaG, C-terminal domain |Escherichia coli [TaxId: 562]
 d1u5ta1 :    (THR23)   (ARG81)   [view usage] : a.4.5.54 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |Vacuolar sorting protein domain |Vacuolar sorting protein SNF8 |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d2doea1 :   (GLY792)  (LYS849)   [view usage] : a.159.2.1 |Another 3-helical bundle |FF domain |FF domain |Transcription elongation regulator 1 |Human (Homo sapiens) [TaxId: 9606]
 d2z43b1 :    (SER21)   (ASP70)   [view usage] : a.60.4.1 |SAM domain-like |Rad51 N-terminal domain-like |DNA repair protein Rad51, N-terminal domain |DNA repair protein Rad51, N-terminal domain |Sulfolobus solfataricus [TaxId: 273057]
 d2wp9c_ :    (ILE22)  (VAL128)   [view usage] : f.21.2.2 |Heme-binding four-helical bundle |Fumarate reductase respiratory complex transmembrane subunits |Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) |Succinate dehydrogenase subunit SdhC |Escherichia coli [TaxId: 562]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
   c.1,    d.92,    a.93,    c.72,    c.37,     e.6,     d.2,    a.96,    f.21,   a.100,     a.4,     a.3,    a.83,    a.60,    a.28,    a.21,   a.174,   a.159,   a.121,   d.189,  
a.173, a.139, a.236, a.36