Protein Concepts Dictionary

Tableau information

Concept source:  d1tvfa2  amino acid (a.a.) range (THR204)(THR240)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: HHEE

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (THR204)  (THR219) H1
	  (LEU223)  (GLN228) H2
	  (LEU229)  (THR233) E3
	  (ALA235)  (THR240) E4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                          
H2     -115.1°   H2                   
E3       66.9°  -99.5°   E3            
E4     -125.5°  -93.7°  155.2°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±13.0°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d1o7fa1 :   (SER182)  (ARG215)   [view usage] : a.4.5.31 |DNA/RNA-binding 3-helical bundle |"Winged helix" DNA-binding domain |DEP domain |Regulatory domain of epac2, domain 2 |Mouse (Mus musculus) [TaxId: 10090]
 d2ahme1 :    (SER81)  (ASP139)   [view usage] : d.302.1.1 |Coronavirus NSP8-like |Coronavirus NSP8-like |Coronavirus NSP8-like |Nonstructural protein 8, NSP8 |SARS coronavirus [TaxId: 227859]
 d1es3a_ :   (ARG155)  (ASN198)   [view usage] : e.3.1.1 |beta-lactamase/transpeptidase-like |beta-lactamase/transpeptidase-like |beta-Lactamase/D-ala carboxypeptidase |D-ala carboxypeptidase/transpeptidase |Streptomyces sp., K15 [TaxId: 1931]
 d1ueab_ :   (SER109)  (ASP149)   [view usage] : b.40.3.1 |OB-fold |TIMP-like |Tissue inhibitor of metalloproteinases, TIMP |TIMP-1 |Human (Homo sapiens) [TaxId: 9606]
 d3huma1 :   (THR204)  (THR240)   [view usage] : e.3.1.1 |beta-lactamase/transpeptidase-like |beta-lactamase/transpeptidase-like |beta-Lactamase/D-ala carboxypeptidase |Pencillin binding protein 4 (PbpD), N-terminal domain |Staphylococcus aureus [TaxId: 1280]
 d1nxca_ :   (GLU549)  (ASP602)   [view usage] : a.102.2.1 |alpha/alpha toroid |Seven-hairpin glycosidases |Class I alpha-1;2-mannosidase, catalytic domain |Class I alpha-1;2-mannosidase, catalytic domain |Mouse (Mus musculus) [TaxId: 10090]
 d1w5ct_ :    (THR56)   (ALA89)   [view usage] : i.5.1.1 |Photosystems |Photosystems |Photosystems |Photosystem II |Thermosynechococcus vulcanus [TaxId: 32053]
 d2j0nb_ :   (TRP135)  (GLN191)   [view usage] : a.250.1.1 |IpaD-like |IpaD-like |IpaD-like |Invasin IpaD |Shigella flexneri [TaxId: 623]
 d1ynjd1 :   (SER110)  (THR154)   [view usage] : e.29.1.2 |beta and beta-prime subunits of DNA dependent RNA-polymerase |beta and beta-prime subunits of DNA dependent RNA-polymerase |RNA-polymerase beta-prime |RNA-polymerase beta-prime |Thermus aquaticus [TaxId: 271]
 d3ne6a2 :   (LEU566)  (SER628)   [view usage] : e.8.1.1 |DNA/RNA polymerases |DNA/RNA polymerases |DNA polymerase I |Family B DNA polymerase |Bacteriophage RB69 [TaxId: 12353]
 d3klia1 :   (GLU194)  (PRO236)   [view usage] : e.8.1.2 |DNA/RNA polymerases |DNA/RNA polymerases |Reverse transcriptase |HIV-1 reverse transcriptase |Human immunodeficiency virus type 1 [TaxId: 11676]
 d1lcsa_ :    (ASP42)  (LYS124)   [view usage] : b.20.1.1 |ENV polyprotein, receptor-binding domain |ENV polyprotein, receptor-binding domain |ENV polyprotein, receptor-binding domain |FLV receptor-binding domain |Feline leukemia virus, strain b/lambda-b1 [TaxId: 11768]
 d2b5ea3 :   (ASP294)  (LEU327)   [view usage] : c.47.1.2 |Thioredoxin fold |Thioredoxin-like |PDI-like |Protein disulfide isomerase, PDI |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1mx9d_ :  (GLY4477) (GLU4519)   [view usage] : c.69.1.1 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |Acetylcholinesterase-like |Mammalian carboxylesterase (liver carboxylesterase I) |Human (Homo sapiens) [TaxId: 9606]
 d2cu9a1 :    (ASN80)  (MET118)   [view usage] : b.1.22.1 |Immunoglobulin-like beta-sandwich |ASF1-like |ASF1-like |Anti-silencing protein 1, ASF1 |Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896]
 d1x3la_ :     (ARG7)   (GLN41)   [view usage] : c.118.1.0 |GckA/TtuD-like |GckA/TtuD-like |automated matches |automated matches |Pyrococcus horikoshii [TaxId: 70601]
 d2ahmg1 :    (LEU43)  (ASP139)   [view usage] : d.302.1.1 |Coronavirus NSP8-like |Coronavirus NSP8-like |Coronavirus NSP8-like |Nonstructural protein 8, NSP8 |SARS coronavirus [TaxId: 227859]
 d1oa8d_ :   (ALA567)  (LYS590)   [view usage] : b.145.1.1 |AXH domain |AXH domain |AXH domain |Ataxin-1 |Human (Homo sapiens) [TaxId: 9606]
 d3a3ja1 :   (SER179)  (ASN217)   [view usage] : e.3.1.0 |beta-lactamase/transpeptidase-like |beta-lactamase/transpeptidase-like |automated matches |automated matches |Haemophilus influenzae [TaxId: 727]
 d1h4ja_ :   (ASN266)  (THR297)   [view usage] : b.70.1.1 |8-bladed beta-propeller |Quinoprotein alcohol dehydrogenase-like |Quinoprotein alcohol dehydrogenase-like |Methanol dehydrogenase, heavy chain |Methylobacterium extorquens [TaxId: 408]
 d1exea_ :     (THR4)   (PRO52)   [view usage] : a.55.1.1 |IHF-like DNA-binding proteins |IHF-like DNA-binding proteins |Prokaryotic DNA-bending protein |Transcription factor 1, TF1 |Bacteriophage SPO1 [TaxId: 10685]
 d2h5nc_ :    (ALA69)  (ASP103)   [view usage] : a.287.1.2 |TerB-like |TerB-like |PG1108-like |Hypothetical protein PG1108 |Porphyromonas gingivalis [TaxId: 837]
 d1an5a_ :    (THR78)  (ILE112)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase |Escherichia coli [TaxId: 562]
 d1skfa_ :   (THR153)  (ASN200)   [view usage] : e.3.1.1 |beta-lactamase/transpeptidase-like |beta-lactamase/transpeptidase-like |beta-Lactamase/D-ala carboxypeptidase |D-ala carboxypeptidase/transpeptidase |Streptomyces sp., K15 [TaxId: 1931]
 d1w2la_ :     (LEU5)   (VAL51)   [view usage] : a.3.1.0 |Cytochrome c |Cytochrome c |automated matches |automated matches |Rhodothermus marinus [TaxId: 29549]
 d3qj7a_ :    (THR78)  (ILE112)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |automated matches |Mycobacterium tuberculosis [TaxId: 1773]
 d1aiqa_ :    (THR78)  (ILE112)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase |Escherichia coli [TaxId: 562]
 d1tvfa2 :   (THR204)  (THR240)   [view usage] : e.3.1.1 |beta-lactamase/transpeptidase-like |beta-lactamase/transpeptidase-like |beta-Lactamase/D-ala carboxypeptidase |Pencillin binding protein 4 (PbpD), N-terminal domain |Staphylococcus aureus [TaxId: 1280]
 d1ffla_ :    (THR78)  (ILE112)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase |Escherichia coli [TaxId: 562]
 d3ntva_ :   (ASP185)  (ILE229)   [view usage] : c.66.1.0 |S-adenosyl-L-methionine-dependent methyltransferases |S-adenosyl-L-methionine-dependent methyltransferases |automated matches |automated matches |Staphylococcus aureus [TaxId: 196620]
 d3it9d1 :   (THR157)  (ASN193)   [view usage] : e.3.1.0 |beta-lactamase/transpeptidase-like |beta-lactamase/transpeptidase-like |automated matches |automated matches |Escherichia coli [TaxId: 562]
 d1aola_ :    (ASP44)  (ASN167)   [view usage] : b.20.1.1 |ENV polyprotein, receptor-binding domain |ENV polyprotein, receptor-binding domain |ENV polyprotein, receptor-binding domain |F-MuLV receptor-binding domain |Friend murine leukemia virus [TaxId: 11795]
 d1es5a_ :   (THR153)  (ASN198)   [view usage] : e.3.1.1 |beta-lactamase/transpeptidase-like |beta-lactamase/transpeptidase-like |beta-Lactamase/D-ala carboxypeptidase |D-ala carboxypeptidase/transpeptidase |Streptomyces sp., K15 [TaxId: 1931]
 d4fogd_ :    (THR78)  (ILE112)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |automated matches |Mycobacterium tuberculosis [TaxId: 83332]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  b.70,     e.8,     e.3,    c.69,   a.102,   d.117,    c.66,    b.40,    c.47,     i.5,     b.1,   b.145,     a.4,     a.3,    a.55,   c.118,    e.29,   a.287,   a.250,   d.302,  
b.20