Protein Concepts Dictionary

Tableau information

Concept source:  d3hgma_  amino acid (a.a.) range (PRO98)(VAL147)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: HEHE

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	   (PRO98)  (GLU110) H1
	  (ASP112)  (GLY117) E2
	  (GLY130)  (ALA140) H3
	  (CYS142)  (VAL147) E4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                          
E2      151.5°   E2                   
H3      -35.0° -163.7°   H3            
E4      126.4°  -25.3° -150.2°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±8.7°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d1cgwa4 :   (ASN204)  (VAL262)   [view usage] : c.1.8.1 |TIM beta/alpha-barrel |(Trans)glycosidases |Amylase, catalytic domain |Cyclodextrin glycosyltransferase |Bacillus circulans, different strains [TaxId: 1397]
 d3ga5a_ :    (GLY74)  (GLY109)   [view usage] : c.93.1.1 |Periplasmic binding protein-like I |Periplasmic binding protein-like I |L-arabinose binding protein-like |Galactose/glucose-binding protein |Salmonella typhimurium, strain lt2 [TaxId: 90371]
 d1llqa2 :   (LYS245)  (ASP295)   [view usage] : c.58.1.3 |Aminoacid dehydrogenase-like, N-terminal domain |Aminoacid dehydrogenase-like, N-terminal domain |Malic enzyme N-domain |Mitochondrial NAD(P)-dependent malic enzyme |Pig roundworm (Ascaris suum) [TaxId: 6253]
 d4bp0a_ :    (ASN81)  (SER130)   [view usage] : d.157.1.0 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |automated matches |automated matches |Pseudomonas aeruginosa [TaxId: 287]
 d1ynya2 :   (PRO214)  (CYS264)   [view usage] : c.1.9.6 |TIM beta/alpha-barrel |Metallo-dependent hydrolases |Hydantoinase (dihydropyrimidinase), catalytic domain |D-hydantoinase |Bacillus sp. AR9 [TaxId: 301298]
 d4jnza2 :   (TYR350)  (GLN404)   [view usage] : c.1.23.2 |TIM beta/alpha-barrel |FAD-linked oxidoreductase |Proline dehydrohenase domain of bifunctional PutA protein |Proline dehydrohenase domain of bifunctional PutA protein |Escherichia coli K-12 [TaxId: 83333]
 d4jnza2 :   (ASN488)  (GLY544)   [view usage] : c.1.23.2 |TIM beta/alpha-barrel |FAD-linked oxidoreductase |Proline dehydrohenase domain of bifunctional PutA protein |Proline dehydrohenase domain of bifunctional PutA protein |Escherichia coli K-12 [TaxId: 83333]
 d4koda3 :   (GLY280)  (ALA346)   [view usage] : c.37.1.20 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |Extended AAA-ATPase domain |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d4kode3 :   (GLY280)  (ALA346)   [view usage] : c.37.1.20 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |Extended AAA-ATPase domain |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d4ppya_ :   (HIS124)  (ASP190)   [view usage] : c.23.10.0 |Flavodoxin-like |SGNH hydrolase |automated matches |automated matches |Bacteroides fragilis [TaxId: 272559]
 d3hmua_ :   (PRO199)  (GLU262)   [view usage] : c.67.1.0 |PLP-dependent transferase-like |PLP-dependent transferases |automated matches |automated matches |Silicibacter pomeroyi [TaxId: 89184]
 d1mv8a3 :   (ASP383)  (LEU419)   [view usage] : c.26.3.1 |Adenine nucleotide alpha hydrolase-like |UDP-glucose/GDP-mannose dehydrogenase C-terminal domain |UDP-glucose/GDP-mannose dehydrogenase C-terminal domain |GDP-mannose 6-dehydrogenase, GDP-binding domain |Pseudomonas aeruginosa [TaxId: 287]
 d2d3wa_ :   (ASN143)  (VAL201)   [view usage] : c.37.1.0 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |automated matches |automated matches |Escherichia coli [TaxId: 562]
 d2b0ta_ :   (ASP459)  (LEU515)   [view usage] : c.77.1.2 |Isocitrate/Isopropylmalate dehydrogenase-like |Isocitrate/Isopropylmalate dehydrogenase-like |Monomeric isocitrate dehydrogenase |automated matches |Corynebacterium glutamicum [TaxId: 1718]
 d1uuqa_ :    (ARG61)  (PHE131)   [view usage] : c.1.8.3 |TIM beta/alpha-barrel |(Trans)glycosidases |beta-glycanases |Exomannosidase |Cellvibrio mixtus [TaxId: 39650]
 d2yhka_ :   (LEU160)  (ALA215)   [view usage] : c.67.1.2 |PLP-dependent transferase-like |PLP-dependent transferases |Beta-eliminating lyases |automated matches |Citrobacter freundii [TaxId: 546]
 d1o20a_ :   (ASN126)  (ASN180)   [view usage] : c.82.1.1 |ALDH-like |ALDH-like |ALDH-like |Gamma-glutamyl phosphate reductase |Thermotoga maritima [TaxId: 2336]
 d1vjra_ :    (THR95)  (THR146)   [view usage] : c.108.1.14 |HAD-like |HAD-like |NagD-like |Hypothetical protein TM1742 |Thermotoga maritima [TaxId: 2336]
 d1tv7a_ :   (ALA145)  (GLU195)   [view usage] : c.1.28.3 |TIM beta/alpha-barrel |Radical SAM enzymes |MoCo biosynthesis proteins |Molybdenum cofactor biosynthesis protein A MoaA |Staphylococcus aureus [TaxId: 1280]
 d2qs8a2 :    (GLU87)  (ALA140)   [view usage] : c.1.9.18 |TIM beta/alpha-barrel |Metallo-dependent hydrolases |Zn-dependent arginine carboxypeptidase-like |Xaa-Pro dipeptidase |Alteromonas macleodii [TaxId: 28108]
 d3o0da_ :   (HIS126)  (GLY188)   [view usage] : c.69.1.0 |alpha/beta-Hydrolases |alpha/beta-Hydrolases |automated matches |automated matches |Yarrowia lipolytica [TaxId: 4952]
 d2b0aa1 :   (LEU112)  (ASN149)   [view usage] : c.8.8.1 |The "swivelling" beta/beta/alpha domain |Putative cyclase |Putative cyclase |Hypothetical protein MJ0783 |Methanococcus jannaschii [TaxId: 2190]
 d1ny5a2 :   (GLY225)  (ASN280)   [view usage] : c.37.1.20 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |Extended AAA-ATPase domain |Transcriptional activator sigm54 (NtrC1), C-terminal domain |Aquifex aeolicus [TaxId: 63363]
 d1jdwa_ :   (ILE304)  (PRO340)   [view usage] : d.126.1.2 |Pentein, beta/alpha-propeller |Pentein |Amidinotransferase |L-arginine: glycine amidinotransferase |Human (Homo sapiens) [TaxId: 9606]
 d1gz4a2 :   (GLN229)  (ASP279)   [view usage] : c.58.1.3 |Aminoacid dehydrogenase-like, N-terminal domain |Aminoacid dehydrogenase-like, N-terminal domain |Malic enzyme N-domain |Mitochondrial NAD(P)-dependent malic enzyme |Human (Homo sapiens) [TaxId: 9606]
 d1o9la2 :   (ASN300)  (GLU344)   [view usage] : c.124.1.3 |NagB/RpiA/CoA transferase-like |NagB/RpiA/CoA transferase-like |CoA transferase beta subunit-like |Succinate:CoA transferase, C-terminal domain |Pig (Sus scrofa) [TaxId: 9823]
 d2zk7b_ :   (ILE116)  (THR176)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Thermoplasma acidophilum [TaxId: 2303]
 d1kcxa2 :   (GLU229)  (ILE279)   [view usage] : c.1.9.6 |TIM beta/alpha-barrel |Metallo-dependent hydrolases |Hydantoinase (dihydropyrimidinase), catalytic domain |Dihydropyrimidinase related protein-1 |Mouse (Mus musculus) [TaxId: 10090]
 d3e2qa2 :   (TYR350)  (GLN404)   [view usage] : c.1.23.2 |TIM beta/alpha-barrel |FAD-linked oxidoreductase |Proline dehydrohenase domain of bifunctional PutA protein |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d3e2qa2 :   (ASN488)  (THR545)   [view usage] : c.1.23.2 |TIM beta/alpha-barrel |FAD-linked oxidoreductase |Proline dehydrohenase domain of bifunctional PutA protein |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d2pjua1 :    (SER89)  (TYR135)   [view usage] : c.92.3.1 |Chelatase-like |PrpR receptor domain-like |PrpR receptor domain-like |Propionate catabolism operon regulatory protein PrpR |Escherichia coli [TaxId: 562]
 d1j6oa_ :    (ARG16)   (VAL58)   [view usage] : c.1.9.12 |TIM beta/alpha-barrel |Metallo-dependent hydrolases |TatD Mg-dependent DNase-like |Hypothetical protein TM0667 |Thermotoga maritima [TaxId: 2336]
 d2jdxa_ :   (ILE304)  (PRO340)   [view usage] : d.126.1.2 |Pentein, beta/alpha-propeller |Pentein |Amidinotransferase |L-arginine: glycine amidinotransferase |Human (Homo sapiens) [TaxId: 9606]
 d4bp0b_ :    (ASN81)  (SER130)   [view usage] : d.157.1.0 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |automated matches |automated matches |Pseudomonas aeruginosa [TaxId: 287]
 d3ouub1 :    (ILE64)  (ILE104)   [view usage] : c.30.1.0 |PreATP-grasp domain |PreATP-grasp domain |automated matches |automated matches |Campylobacter jejuni [TaxId: 192222]
 d4ppyb_ :   (HIS124)  (ASP190)   [view usage] : c.23.10.0 |Flavodoxin-like |SGNH hydrolase |automated matches |automated matches |Bacteroides fragilis [TaxId: 272559]
 d2xvxa_ :    (SER66)  (LEU119)   [view usage] : c.92.1.0 |Chelatase-like |Chelatase |automated matches |automated matches |Desulfovibrio vulgaris [TaxId: 882]
 d2i6ea1 :   (THR139)  (LEU190)   [view usage] : c.94.1.1 |Periplasmic binding protein-like II |Periplasmic binding protein-like II |Phosphate binding protein-like |Hypothetical protein DR0370 |Deinococcus radiodurans [TaxId: 1299]
 d1tv7b_ :   (THR146)  (GLU195)   [view usage] : c.1.28.3 |TIM beta/alpha-barrel |Radical SAM enzymes |MoCo biosynthesis proteins |Molybdenum cofactor biosynthesis protein A MoaA |Staphylococcus aureus [TaxId: 1280]
 d1twia2 :    (SER50)  (SER105)   [view usage] : c.1.6.1 |TIM beta/alpha-barrel |PLP-binding barrel |Alanine racemase-like, N-terminal domain |Diaminopimelate decarboxylase LysA |Methanococcus jannaschii [TaxId: 2190]
 d4wuta_ :   (ASN133)  (GLN192)   [view usage] : c.93.1.0 |Periplasmic binding protein-like I |Periplasmic binding protein-like I |automated matches |automated matches |Agrobacterium vitis [TaxId: 311402]
 d2ycpa_ :   (LEU160)  (ALA215)   [view usage] : c.67.1.2 |PLP-dependent transferase-like |PLP-dependent transferases |Beta-eliminating lyases |automated matches |Citrobacter freundii [TaxId: 546]
 d3riha_ :   (LEU140)  (ASN202)   [view usage] : c.2.1.0 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |automated matches |automated matches |Mycobacterium abscessus [TaxId: 561007]
 d3d02a_ :   (GLU142)  (THR188)   [view usage] : c.93.1.0 |Periplasmic binding protein-like I |Periplasmic binding protein-like I |automated matches |automated matches |Klebsiella pneumoniae [TaxId: 272620]
 d1s1i0_ :    (ASN78)  (THR120)   [view usage] : i.1.1.1 |Ribosome and ribosomal fragments |Ribosome and ribosomal fragments |Ribosome complexes |Eukaryotic, cytoplasmic (80S ribosome functional complex) |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1gz3a2 :   (GLN229)  (ASP279)   [view usage] : c.58.1.3 |Aminoacid dehydrogenase-like, N-terminal domain |Aminoacid dehydrogenase-like, N-terminal domain |Malic enzyme N-domain |Mitochondrial NAD(P)-dependent malic enzyme |Human (Homo sapiens) [TaxId: 9606]
 d1cl2b_ :    (ASN92)  (TRP131)   [view usage] : c.67.1.3 |PLP-dependent transferase-like |PLP-dependent transferases |Cystathionine synthase-like |Cystathionine beta-lyase, CBL |Escherichia coli [TaxId: 562]
 d2ji8b3 :   (MET432)  (MET477)   [view usage] : c.36.1.9 |Thiamin diphosphate-binding fold (THDP-binding) |Thiamin diphosphate-binding fold (THDP-binding) |Pyruvate oxidase and decarboxylase PP module |Oxalyl-CoA decarboxylase |Oxalobacter formigenes [TaxId: 847]
 d1zjja_ :    (THR68)  (THR107)   [view usage] : c.108.1.0 |HAD-like |HAD-like |automated matches |automated matches |Pyrococcus horikoshii [TaxId: 70601]
 d3ouza1 :    (ILE64)  (ILE104)   [view usage] : c.30.1.0 |PreATP-grasp domain |PreATP-grasp domain |automated matches |automated matches |Campylobacter jejuni [TaxId: 192222]
 d3ieka_ :   (GLY382)  (PHE425)   [view usage] : d.157.1.10 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |beta-CASP RNA-metabolising hydrolases |Putative RNA-degradation protein TTHA0252 |Thermus thermophilus [TaxId: 274]
 d4rk5a_ :   (HIS160)  (ASP214)   [view usage] : c.93.1.0 |Periplasmic binding protein-like I |Periplasmic binding protein-like I |automated matches |automated matches |Lactobacillus casei [TaxId: 321967]
 d3wjaa1 :   (SER229)  (ASP279)   [view usage] : c.58.1.0 |Aminoacid dehydrogenase-like, N-terminal domain |Aminoacid dehydrogenase-like, N-terminal domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1yi8a_ :   (TYR150)  (ALA199)   [view usage] : c.26.1.0 |Adenine nucleotide alpha hydrolase-like |Nucleotidylyl transferase |automated matches |automated matches |Deinococcus radiodurans [TaxId: 243230]
 d1m63a_ :    (GLN94)  (ARG148)   [view usage] : d.159.1.3 |Metallo-dependent phosphatases |Metallo-dependent phosphatases |Protein serine/threonine phosphatase |Protein phosphatase-2B (PP-2B, calcineurin A subunit) |Human (Homo sapiens) [TaxId: 9606]
 d2hi6a1 :    (GLY64)  (ARG105)   [view usage] : c.8.2.3 |The "swivelling" beta/beta/alpha domain |LeuD/IlvD-like |AF0055-like |Hypothetical protein AF0055 |Archaeoglobus fulgidus [TaxId: 2234]
 d1c14a_ :   (SER121)  (GLY190)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |Enoyl-ACP reductase |Escherichia coli [TaxId: 562]
 d4m7ya_ :   (THR188)  (VAL251)   [view usage] : c.55.1.14 |Ribonuclease H-like motif |Actin-like ATPase domain |Fumble-like |automated matches |Staphylococcus aureus [TaxId: 196620]
 d1x1oa2 :   (ILE117)  (ARG162)   [view usage] : c.1.17.0 |TIM beta/alpha-barrel |Nicotinate/Quinolinate PRTase C-terminal domain-like |automated matches |automated matches |Thermus thermophilus HB8 [TaxId: 300852]
 d2vjya3 :   (GLN367)  (ASN402)   [view usage] : c.36.1.0 |Thiamin diphosphate-binding fold (THDP-binding) |Thiamin diphosphate-binding fold (THDP-binding) |automated matches |automated matches |Milk yeast (Kluyveromyces lactis) [TaxId: 28985]
 d1mg5a_ :   (ILE101)  (GLY183)   [view usage] : c.2.1.2 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Tyrosine-dependent oxidoreductases |Drosophila alcohol dehydrogenase |Fruit fly (Drosophila melanogaster) [TaxId: 7227]
 d3hmub_ :   (ASP198)  (GLU262)   [view usage] : c.67.1.0 |PLP-dependent transferase-like |PLP-dependent transferases |automated matches |automated matches |Silicibacter pomeroyi [TaxId: 89184]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
   c.1,    c.67,    c.69,    c.94,     c.2,   d.159,     i.1,   c.108,    c.82,    c.26,    c.92,   d.157,    c.77,   c.124,    c.93,    c.23,    c.37,    c.36,    c.55,   d.126,  
c.8, c.30, c.58