Protein Concepts Dictionary

Tableau information

Concept source:  d1y5hb3  amino acid (a.a.) range (SER86)(LEU123)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: HEEH

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	   (SER86)   (GLN98) H1
	  (ARG100)  (SER106) E2
	  (GLY112)  (GLU116) E3
	  (GLU116)  (LEU123) H4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          H1                          
E2      128.8°   E2                   
E3      -73.4°  148.9°   E3            
H4     -144.0°   86.6°  -71.3°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±11.6°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d3rkka_ :   (ASP225)  (ARG270)   [view usage] : d.157.1.0 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |automated matches |automated matches |Klebsiella pneumoniae [TaxId: 573]
 d1g0u2_ :   (SER147)  (LEU187)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |Proteasome beta subunit (catalytic) |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1nrza_ :   (PRO125)  (GLU160)   [view usage] : c.38.1.1 |PTS IIb component |PTS IIb component |PTS IIb component |Sorbose permease subunit IIb , EIIb-sor |Klebsiella pneumoniae [TaxId: 573]
 d3k2vb_ :   (LEU295)  (ARG330)   [view usage] : d.37.1.0 |CBS-domain pair |CBS-domain pair |automated matches |automated matches |Klebsiella pneumoniae [TaxId: 272620]
 d3oz7b_ :   (HIS124)  (LEU156)   [view usage] : c.86.1.1 |Phosphoglycerate kinase |Phosphoglycerate kinase |Phosphoglycerate kinase |Phosphoglycerate kinase |Malaria parasite (Plasmodium falciparum) [TaxId: 5833]
 d3qmlb2 :   (ALA318)  (ASN351)   [view usage] : c.55.1.0 |Ribonuclease H-like motif |Actin-like ATPase domain |automated matches |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1z1ga2 :   (LYS220)  (GLY267)   [view usage] : d.163.1.1 |DNA breaking-rejoining enzymes |DNA breaking-rejoining enzymes |Lambda integrase-like, catalytic core |Integrase (Int) |Bacteriophage lambda [TaxId: 10710]
 d3k2va_ :   (ALA296)  (ARG330)   [view usage] : d.37.1.0 |CBS-domain pair |CBS-domain pair |automated matches |automated matches |Klebsiella pneumoniae [TaxId: 272620]
 d1i19a2 :    (GLN98)  (ASN147)   [view usage] : d.145.1.1 |FAD-binding/transporter-associated domain-like |FAD-binding/transporter-associated domain-like |FAD-linked oxidases, N-terminal domain |Cholesterol oxidase |Brevibacterium sterolicum [TaxId: 1702]
 d1f4ca_ :    (TYR94)  (LYS120)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase |Escherichia coli [TaxId: 562]
 d1ohca1 :   (THR147)  (GLN191)   [view usage] : c.45.1.1 |(Phosphotyrosine protein) phosphatases II |(Phosphotyrosine protein) phosphatases II |Dual specificity phosphatase-like |Proline directed phosphatase CDC14b2 |Human (Homo sapiens) [TaxId: 9606]
 d1qpga_ :   (HIS123)  (SER153)   [view usage] : c.86.1.1 |Phosphoglycerate kinase |Phosphoglycerate kinase |Phosphoglycerate kinase |Phosphoglycerate kinase |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1vq0a2 :   (LYS248)  (ASP286)   [view usage] : g.81.1.1 |HSP33 redox switch-like |HSP33 redox switch-like |HSP33 redox switch-like |HSP33, C-terminal domain |Thermotoga maritima [TaxId: 2336]
 d2g8xa_ :    (VAL93)  (LYS120)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase |Escherichia coli [TaxId: 562]
 d2e9fd_ :   (SER109)  (ALA174)   [view usage] : a.127.1.0 |L-aspartase-like |L-aspartase-like |automated matches |automated matches |Thermus thermophilus HB8 [TaxId: 300852]
 d3wxrg_ :   (SER187)  (ASN247)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 559292]
 d1vzya2 :   (LYS252)  (GLN288)   [view usage] : g.81.1.1 |HSP33 redox switch-like |HSP33 redox switch-like |HSP33 redox switch-like |HSP33, C-terminal domain |Bacillus subtilis [TaxId: 1423]
 d1blea_ :   (THR124)  (THR162)   [view usage] : c.38.1.1 |PTS IIb component |PTS IIb component |PTS IIb component |Fructose permease, subunit IIb |Bacillus subtilis [TaxId: 1423]
 d1qoya_ :   (GLY180)  (GLY201)   [view usage] : h.4.4.1 |Antiparallel coiled-coil |Bacterial hemolysins |Hemolysin E (HlyE, ClyA, SheA) |Hemolysin E (HlyE, ClyA, SheA) |Escherichia coli [TaxId: 562]
 d1tygg_ :    (ILE18)   (GLU48)   [view usage] : d.15.3.2 |beta-Grasp (ubiquitin-like) |MoaD/ThiS |ThiS |Thiamin biosynthesis sulfur carrier protein ThiS |Bacillus subtilis [TaxId: 1423]
 d1pbja3 :    (THR83)  (MSE121)   [view usage] : d.37.1.1 |CBS-domain pair |CBS-domain pair |CBS-domain pair |Hypothetical protein MTH1622 |Methanobacterium thermoautotrophicum [TaxId: 145262]
 d3fhma_ :    (SER24)   (GLY64)   [view usage] : d.37.1.0 |CBS-domain pair |CBS-domain pair |automated matches |automated matches |Agrobacterium tumefaciens [TaxId: 176299]
 d3spue_ :   (ASP225)  (ASP267)   [view usage] : d.157.1.0 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |automated matches |automated matches |Klebsiella pneumoniae [TaxId: 573]
 d2yzib_ :    (LEU92)  (ARG130)   [view usage] : d.37.1.1 |CBS-domain pair |CBS-domain pair |CBS-domain pair |automated matches |Pyrococcus horikoshii [TaxId: 53953]
 d4h0rb_ :    (VAL96)  (ARG123)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |automated matches |Corynebacterium glutamicum [TaxId: 196627]
 d1moma_ :   (SER191)  (ASN236)   [view usage] : d.165.1.1 |Ribosome inactivating proteins (RIP) |Ribosome inactivating proteins (RIP) |Plant cytotoxins |alpha-Momorcharin (momordin) |Bitter gourd (Momordica charantia) [TaxId: 3673]
 d2qr1g1 :    (VAL43)   (SER88)   [view usage] : d.37.1.1 |CBS-domain pair |CBS-domain pair |CBS-domain pair |automated matches |Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896]
 d2fhh2_ :   (ASP459)  (SER522)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |automated matches |Mycobacterium tuberculosis [TaxId: 1773]
 d3pg4a_ :   (ASP225)  (HIS274)   [view usage] : d.157.1.0 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |automated matches |automated matches |Klebsiella pneumoniae [TaxId: 573]
 d2e9fb_ :   (SER109)  (ASN194)   [view usage] : a.127.1.0 |L-aspartase-like |L-aspartase-like |automated matches |automated matches |Thermus thermophilus HB8 [TaxId: 300852]
 d3spub_ :   (ASP225)  (ASP267)   [view usage] : d.157.1.0 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |automated matches |automated matches |Klebsiella pneumoniae [TaxId: 573]
 d3ddja1 :   (VAL227)  (LYS276)   [view usage] : d.37.1.1 |CBS-domain pair |CBS-domain pair |CBS-domain pair |Uncharacterized protein SSO3205 |Sulfolobus solfataricus [TaxId: 2287]
 d3k6ea_ :   (THR101)  (HIS142)   [view usage] : d.37.1.0 |CBS-domain pair |CBS-domain pair |automated matches |automated matches |Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]
 d2rc3a1 :    (VAL46)   (LYS81)   [view usage] : d.37.1.1 |CBS-domain pair |CBS-domain pair |CBS-domain pair |Uncharacterized protein NE2398 |Nitrosomonas europaea [TaxId: 915]
 d2oaua1 :   (GLY113)  (GLY173)   [view usage] : b.38.1.3 |Sm-like fold |Sm-like ribonucleoproteins |Mechanosensitive channel protein MscS (YggB), middle domain |Mechanosensitive channel protein MscS (YggB), middle domain |Escherichia coli [TaxId: 562]
 d1zfja4 :   (LEU173)  (PRO213)   [view usage] : d.37.1.1 |CBS-domain pair |CBS-domain pair |CBS-domain pair |Type II inosine monophosphate dehydrogenase CBS domains |Streptococcus pyogenes [TaxId: 1314]
 d1y5ha3 :    (SER86)  (HIS122)   [view usage] : d.37.1.1 |CBS-domain pair |CBS-domain pair |CBS-domain pair |Hypothetical protein Rv2626c |Mycobacterium tuberculosis [TaxId: 1773]
 d3di1b_ :   (ILE248)  (LYS290)   [view usage] : c.1.10.0 |TIM beta/alpha-barrel |Aldolase |automated matches |automated matches |Staphylococcus aureus [TaxId: 93062]
 d1eyua_ :    (ASN87)  (SER133)   [view usage] : c.52.1.6 |Restriction endonuclease-like |Restriction endonuclease-like |Restriction endonuclease PvuII |Restriction endonuclease PvuII |Proteus vulgaris [TaxId: 585]
 d2i0ka2 :    (GLN98)  (ASN147)   [view usage] : d.145.1.0 |FAD-binding/transporter-associated domain-like |FAD-binding/transporter-associated domain-like |automated matches |automated matches |Brevibacterium sterolicum [TaxId: 1702]
 d1hh8a_ :    (TYR87)  (GLU135)   [view usage] : a.118.8.1 |alpha-alpha superhelix |TPR-like |Tetratricopeptide repeat (TPR) |Neutrophil cytosolic factor 2 (NCF-2, p67-phox) |Human (Homo sapiens) [TaxId: 9606]
 d1zata2 :   (GLN219)  (LEU251)   [view usage] : d.335.1.1 |L,D-transpeptidase pre-catalytic domain-like |L,D-transpeptidase pre-catalytic domain-like |L,D-transpeptidase pre-catalytic domain-like |L,D-transpeptidase, pre-catalytic domain |Enterococcus faecium [TaxId: 1352]
 d2jr7a_ :    (THR35)   (SER66)   [view usage] : g.41.17.1 |Rubredoxin-like |CSL zinc finger |CSL zinc finger |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d3l0ja_ :   (GLN346)  (HIS411)   [view usage] : a.123.1.0 |Nuclear receptor ligand-binding domain |Nuclear receptor ligand-binding domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1wz7b_ :    (ILE54)   (GLN98)   [view usage] : d.330.1.1 |ERH-like |ERH-like |ERH-like |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d2ef7a1 :    (THR87)  (PHE127)   [view usage] : d.37.1.1 |CBS-domain pair |CBS-domain pair |CBS-domain pair |Uncharacterized protein ST2348 |Sulfolobus tokodaii [TaxId: 111955]
 d3rkja_ :   (TYR229)  (ARG270)   [view usage] : d.157.1.0 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |automated matches |automated matches |Klebsiella pneumoniae [TaxId: 573]
 d1vzyb2 :   (LYS251)  (GLY284)   [view usage] : g.81.1.1 |HSP33 redox switch-like |HSP33 redox switch-like |HSP33 redox switch-like |HSP33, C-terminal domain |Bacillus subtilis [TaxId: 1423]
 d2rc3c_ :    (SER45)   (LYS81)   [view usage] : d.37.1.1 |CBS-domain pair |CBS-domain pair |CBS-domain pair |Uncharacterized protein NE2398 |Nitrosomonas europaea [TaxId: 915]
 d1kf0a_ :   (HIS124)  (LYS155)   [view usage] : c.86.1.1 |Phosphoglycerate kinase |Phosphoglycerate kinase |Phosphoglycerate kinase |Phosphoglycerate kinase |Pig (Sus scrofa) [TaxId: 9823]
 d1f4cb_ :    (TYR94)  (ASP122)   [view usage] : d.117.1.1 |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase/dCMP hydroxymethylase |Thymidylate synthase |Escherichia coli [TaxId: 562]
 d2l6qa_ :     (ARG3)   (THR54)   [view usage] : d.186.1.1 |gpW/XkdW-like |Head-to-tail joining protein W, gpW |Head-to-tail joining protein W, gpW |Head-to-tail joining protein W, gpW |Bacteriophage lambda [TaxId: 10710]
 d1ni0a_ :    (PRO88)  (GLU121)   [view usage] : c.52.1.6 |Restriction endonuclease-like |Restriction endonuclease-like |Restriction endonuclease PvuII |Restriction endonuclease PvuII |Proteus vulgaris [TaxId: 585]
 d3wxrv_ :   (SER147)  (LEU196)   [view usage] : d.153.1.4 |Ntn hydrolase-like |N-terminal nucleophile aminohydrolases (Ntn hydrolases) |Proteasome subunits |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 559292]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
   c.1,   a.118,   d.157,   d.117,    c.45,   d.165,   a.127,    c.55,    c.86,   d.153,   a.123,    d.37,    c.52,   d.145,    c.38,    b.38,    d.15,     h.4,    g.41,   d.163,  
d.186, g.81, d.335, d.330