Tableau information
Concept source: d3pcoa_ amino acid (a.a.) range (SER219)(MET274)
nSSEs in this Concept: 4
String of secondary struct.elems. (SSEs) defining this concept: HEEE
Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
(SER219) (PHE234) H1
(LEU239) (PRO245) E2
(PRO253) (LYS262) E3
(LYS265) (MET274) E4
Orientation angles° of SSE-pairs; those in contact shown in bold font
H1
E2 162.2° E2
E3 -19.4° 155.7° E3
E4 142.8° -45.5° 158.8°
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±11.8° about each orientation angle shown above.
Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
d3pvia_ : (ASN35) (ASN73) [view usage] : c.52.1.6 |Restriction endonuclease-like |Restriction endonuclease-like |Restriction endonuclease PvuII |Restriction endonuclease PvuII |Proteus vulgaris [TaxId: 585]
d1lw6i_ : (SER31) (VAL70) [view usage] : d.40.1.1 |CI-2 family of serine protease inhibitors |CI-2 family of serine protease inhibitors |CI-2 family of serine protease inhibitors |Chymotrypsin inhibitor CI-2 |Barley (Hordeum vulgare) [TaxId: 4513]
d4ls4a_ : (SER25) (ARG80) [view usage] : d.298.1.2 |RelE-like |RelE-like |RelE-like |automated matches |Helicobacter pylori [TaxId: 85962]
d1wy5a2 : (ASP279) (LEU311) [view usage] : d.229.1.1 |MesJ substrate recognition domain-like |MesJ substrate recognition domain-like |MesJ substrate recognition domain-like |TilS-like protein Aq_1887 |Aquifex aeolicus [TaxId: 63363]
d3nopc1 : (PRO66) (ILE112) [view usage] : d.110.3.9 |Profilin-like |PYP-like sensor domain (PAS domain) |BphP N-terminal domain-like |Bacteriophytochrome BphP |Pseudomonas aeruginosa [TaxId: 287]
d4h05b_ : (HIS-1) (ALA45) [view usage] : d.144.1.0 |Protein kinase-like (PK-like) |Protein kinase-like (PK-like) |automated matches |automated matches |Streptomyces rimosus [TaxId: 1927]
d4qxpa_ : (ASN211) (PRO264) [view usage] : d.387.1.1 |STING C-terminal-like |STING, TM173 CTD-like |Tyrosinase cofactor MelC1 |Tyrosinase cofactor MelC1 |Human (Homo sapiens) [TaxId: 9606]
d4ltta_ : (ASP24) (ARG80) [view usage] : d.298.1.2 |RelE-like |RelE-like |RelE-like |automated matches |Helicobacter pylori [TaxId: 85962]
d1ni0c_ : (ASN35) (ASN73) [view usage] : c.52.1.6 |Restriction endonuclease-like |Restriction endonuclease-like |Restriction endonuclease PvuII |Restriction endonuclease PvuII |Proteus vulgaris [TaxId: 585]
d1jx1b_ : (GLY125) (ASN180) [view usage] : d.36.1.1 |Chalcone isomerase |Chalcone isomerase |Chalcone isomerase |Chalcone isomerase |Alfalfa (Medicago sativa) [TaxId: 3879]
d1xsna3 : (ILE443) (VAL494) [view usage] : d.218.1.2 |Nucleotidyltransferase |Nucleotidyltransferase |DNA polymerase beta-like |DNA polymerase lambda |Human (Homo sapiens) [TaxId: 9606]
d2j80b_ : (ASP85) (GLY126) [view usage] : d.110.6.1 |Profilin-like |Sensory domain-like |Sensory domain of two-component sensor kinase |automated matches |Klebsiella pneumoniae [TaxId: 573]
d3s7na1 : (TRP82) (PRO128) [view usage] : d.110.3.0 |Profilin-like |PYP-like sensor domain (PAS domain) |automated matches |automated matches |Deinococcus radiodurans [TaxId: 1299]
d1g6oa_ : (PHE36) (ASP69) [view usage] : c.37.1.11 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |RecA protein-like (ATPase-domain) |Hexameric traffic ATPase, HP0525 |Helicobacter pylori [TaxId: 210]
d1hzga_ : (ASN921) (TYR962) [view usage] : d.194.1.1 |CNF1/YfiH-like putative cysteine hydrolases |CNF1/YfiH-like putative cysteine hydrolases |Type 1 cytotoxic necrotizing factor, catalytic domain |Type 1 cytotoxic necrotizing factor, catalytic domain |Escherichia coli [TaxId: 562]
d2ci8a_ : (THR288) (GLY342) [view usage] : d.93.1.0 |SH2-like |SH2 domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
d1tv7a_ : (THR212) (THR254) [view usage] : c.1.28.3 |TIM beta/alpha-barrel |Radical SAM enzymes |MoCo biosynthesis proteins |Molybdenum cofactor biosynthesis protein A MoaA |Staphylococcus aureus [TaxId: 1280]
d2j80a_ : (ASP85) (GLY126) [view usage] : d.110.6.1 |Profilin-like |Sensory domain-like |Sensory domain of two-component sensor kinase |automated matches |Klebsiella pneumoniae [TaxId: 573]
d3rglb_ : (ILE88) (TYR141) [view usage] : d.104.1.1 |Class II aaRS and biotin synthetases |Class II aaRS and biotin synthetases |Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain |automated matches |Campylobacter jejuni [TaxId: 197]
d2fb2a_ : (THR212) (THR254) [view usage] : c.1.28.3 |TIM beta/alpha-barrel |Radical SAM enzymes |MoCo biosynthesis proteins |Molybdenum cofactor biosynthesis protein A MoaA |Staphylococcus aureus [TaxId: 1280]
d2ffga1 : (SER2) (LYS55) [view usage] : d.317.1.1 |YkuJ-like |YkuJ-like |YkuJ-like |Hypothetical protein YkuJ |Bacillus subtilis [TaxId: 1423]
d2fb5a1 : (THR166) (LEU205) [view usage] : d.320.1.1 |YojJ-like |YojJ-like |YojJ-like |Hypothetical protein BC4920 (YojJ) |Bacillus cereus [TaxId: 1396]
d3s7oa1 : (TRP82) (PRO128) [view usage] : d.110.3.0 |Profilin-like |PYP-like sensor domain (PAS domain) |automated matches |automated matches |Deinococcus radiodurans [TaxId: 1299]
d1h9oa_ : (ARG19) (THR63) [view usage] : d.93.1.1 |SH2-like |SH2 domain |SH2 domain |Phosphatidylinositol 3-kinase, p85-alpha subunit |Human (Homo sapiens) [TaxId: 9606]
d1jyoa_ : (LEU1) (ALA41) [view usage] : d.198.1.1 |Secretion chaperone-like |Type III secretory system chaperone-like |Type III secretory system chaperone |Virulence effector SptP secretion chaperone SicP |Salmonella typhimurium [TaxId: 90371]
d2i83a_ : (THR62) (LEU107) [view usage] : d.169.1.4 |C-type lectin-like |C-type lectin-like |Link domain |CD44, hyaluronan binding domain |Human (Homo sapiens) [TaxId: 9606]
d4h6ja_ : (SER284) (SER343) [view usage] : d.110.3.7 |Profilin-like |PYP-like sensor domain (PAS domain) |Hypoxia-inducible factor Hif2a, C-terminal domain |automated matches |Human (Homo sapiens) [TaxId: 9606]
d1ab2a_ : (SER17) (ARG59) [view usage] : d.93.1.1 |SH2-like |SH2 domain |SH2 domain |Proto-oncogen tyrosine kinase |Human (Homo sapiens) [TaxId: 9606]
d1tlua_ : (ILE26) (TRP70) [view usage] : d.156.1.2 |S-adenosylmethionine decarboxylase |S-adenosylmethionine decarboxylase |Bacterial S-adenosylmethionine decarboxylase |S-adenosylmethionine decarboxylase (SamDC, SpeH) |Thermotoga maritima [TaxId: 2336]
d2pvia_ : (ASN35) (ASN73) [view usage] : c.52.1.6 |Restriction endonuclease-like |Restriction endonuclease-like |Restriction endonuclease PvuII |Restriction endonuclease PvuII |Proteus vulgaris [TaxId: 585]
d2ksha_ : (SER5) (GLU55) [view usage] : d.106.1.1 |SCP-like |SCP-like |Sterol carrier protein, SCP |automated matches |Yellow fever mosquito (Aedes aegypti) [TaxId: 7159]
d1do8a1 : (THR429) (GLN464) [view usage] : c.2.1.7 |NAD(P)-binding Rossmann-fold domains |NAD(P)-binding Rossmann-fold domains |Aminoacid dehydrogenase-like, C-terminal domain |Mitochondrial NAD(P)-dependent malic enzyme |Human (Homo sapiens) [TaxId: 9606]
d1oo3a_ : (ARG20) (LYS62) [view usage] : d.93.1.1 |SH2-like |SH2 domain |SH2 domain |Phosphatidylinositol 3-kinase, p85-alpha subunit |Cow (Bos taurus) [TaxId: 9913]
d1ln1a_ : (SER75) (ASP122) [view usage] : d.129.3.2 |TBP-like |Bet v1-like |STAR domain |Phosphatidylcholine transfer protein |Human (Homo sapiens) [TaxId: 9606]
d2o9ba2 : (TRP82) (PRO128) [view usage] : d.110.3.9 |Profilin-like |PYP-like sensor domain (PAS domain) |BphP N-terminal domain-like |Bacteriophytochrome BphP |Deinococcus radiodurans [TaxId: 1299]
d2p9nd2 : (SER123) (ASP171) [view usage] : d.198.2.1 |Secretion chaperone-like |Arp2/3 complex subunits |Arp2/3 complex subunits |ARPC2 (34 kDa subunit) |Cow (Bos taurus) [TaxId: 9913]
d3g6oa1 : (PRO66) (GLU111) [view usage] : d.110.3.9 |Profilin-like |PYP-like sensor domain (PAS domain) |BphP N-terminal domain-like |Bacteriophytochrome BphP |Pseudomonas aeruginosa [TaxId: 287]
d1iqqa_ : (ALA134) (HIS183) [view usage] : d.124.1.1 |Ribonuclease Rh-like |Ribonuclease Rh-like |Ribonuclease Rh-like |S3-RNase |Japanese pear (Pyrus pyrifolia) [TaxId: 3767]
d3c2we3 : (PRO66) (ILE112) [view usage] : d.110.3.9 |Profilin-like |PYP-like sensor domain (PAS domain) |BphP N-terminal domain-like |Bacteriophytochrome BphP |Pseudomonas aeruginosa [TaxId: 287]
d4loha_ : (ASN211) (PRO264) [view usage] : d.387.1.1 |STING C-terminal-like |STING, TM173 CTD-like |Tyrosinase cofactor MelC1 |Tyrosinase cofactor MelC1 |Human (Homo sapiens) [TaxId: 9606]
d1z3ka_ : (ARG10) (LYS52) [view usage] : d.93.1.0 |SH2-like |SH2 domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
d1nj8a3 : (THR159) (GLY224) [view usage] : d.104.1.1 |Class II aaRS and biotin synthetases |Class II aaRS and biotin synthetases |Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain |Prolyl-tRNA synthetase (ProRS) |Methanocaldococcus jannaschii [TaxId: 2190]
d1p0za_ : (GLY82) (GLY126) [view usage] : d.110.6.1 |Profilin-like |Sensory domain-like |Sensory domain of two-component sensor kinase |Sensor kinase CitA |Klebsiella pneumoniae [TaxId: 573]
d4q0ha1 : (TRP82) (PRO128) [view usage] : d.110.3.9 |Profilin-like |PYP-like sensor domain (PAS domain) |BphP N-terminal domain-like |Bacteriophytochrome BphP |Deinococcus radiodurans [TaxId: 243230]
d2qt8b_ : (HIS-2) (GLY68) [view usage] : d.248.1.1 |Coproporphyrinogen III oxidase |Coproporphyrinogen III oxidase |Coproporphyrinogen III oxidase |automated matches |Leishmania major [TaxId: 5664]
d1ttwa_ : (TYR4) (ALA41) [view usage] : d.198.1.1 |Secretion chaperone-like |Type III secretory system chaperone-like |Type III secretory system chaperone |Putative YopH chaperone SycH |Yersinia pestis [TaxId: 632]
d1vrga1 : (THR36) (THR96) [view usage] : c.14.1.4 |ClpP/crotonase |ClpP/crotonase |Biotin dependent carboxylase carboxyltransferase domain |Propionyl-CoA carboxylase complex B subunit, PccB |Thermotoga maritima [TaxId: 2336]
d1k0ka_ : (SER1) (GLN38) [view usage] : d.110.1.1 |Profilin-like |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Profilin (actin-binding protein) |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
d3f1pa_ : (SER286) (SER345) [view usage] : d.110.3.7 |Profilin-like |PYP-like sensor domain (PAS domain) |Hypoxia-inducible factor Hif2a, C-terminal domain |automated matches |Human (Homo sapiens) [TaxId: 9606]
d2g9da1 : (PHE10) (PRO46) [view usage] : c.56.5.7 |Phosphorylase/hydrolase-like |Zn-dependent exopeptidases |AstE/AspA-like |Succinylglutamate desuccinylase AstE |Vibrio cholerae [TaxId: 666]
d4ir8b_ : (THR61) (TRP106) [view usage] : e.7.1.0 |Carbohydrate phosphatase |Carbohydrate phosphatase |automated matches |automated matches |Toxoplasma gondii [TaxId: 508771]
d1tv7b_ : (THR212) (THR254) [view usage] : c.1.28.3 |TIM beta/alpha-barrel |Radical SAM enzymes |MoCo biosynthesis proteins |Molybdenum cofactor biosynthesis protein A MoaA |Staphylococcus aureus [TaxId: 1280]
d2czca1 : (ASN142) (PRO212) [view usage] : d.81.1.1 |FwdE/GAPDH domain-like |Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain |GAPDH-like |Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) |Pyrococcus horikoshii [TaxId: 53953]
d3oeik_ : (ARG22) (LYS80) [view usage] : d.298.1.0 |RelE-like |RelE-like |automated matches |automated matches |Mycobacterium tuberculosis [TaxId: 1773]
d2qt8a_ : (MSE1) (LYS69) [view usage] : d.248.1.1 |Coproporphyrinogen III oxidase |Coproporphyrinogen III oxidase |Coproporphyrinogen III oxidase |automated matches |Leishmania major [TaxId: 5664]
d4loib_ : (ASN211) (PRO264) [view usage] : d.387.1.1 |STING C-terminal-like |STING, TM173 CTD-like |Tyrosinase cofactor MelC1 |Tyrosinase cofactor MelC1 |Human (Homo sapiens) [TaxId: 9606]
d4qxoa_ : (ASN211) (PRO264) [view usage] : d.387.1.1 |STING C-terminal-like |STING, TM173 CTD-like |Tyrosinase cofactor MelC1 |Tyrosinase cofactor MelC1 |Human (Homo sapiens) [TaxId: 9606]
d1kafe_ : (ASP109) (ASN156) [view usage] : d.199.1.1 |MotA C-terminal domain-like |DNA-binding C-terminal domain of the transcription factor MotA |DNA-binding C-terminal domain of the transcription factor MotA |DNA-binding C-terminal domain of the transcription factor MotA |Bacteriophage T4 [TaxId: 10665]
d2iy5b6 : (GLY605) (ALA654) [view usage] : d.104.1.1 |Class II aaRS and biotin synthetases |Class II aaRS and biotin synthetases |Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain |Phenyl-tRNA synthetase (PheRS) beta subunit, PheT, central domain |Thermus thermophilus [TaxId: 274]
d2a24a_ : (SER50) (VAL107) [view usage] : d.110.3.7 |Profilin-like |PYP-like sensor domain (PAS domain) |Hypoxia-inducible factor Hif2a, C-terminal domain |automated matches |Human (Homo sapiens) [TaxId: 9606]
d1fhsa_ : (PRO15) (VAL59) [view usage] : d.93.1.1 |SH2-like |SH2 domain |SH2 domain |Growth factor receptor-bound protein 2 (GRB2) |Human (Homo sapiens) [TaxId: 9606]
d1nlzd_ : (PHE36) (ASP69) [view usage] : c.37.1.11 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |RecA protein-like (ATPase-domain) |Hexameric traffic ATPase, HP0525 |Helicobacter pylori [TaxId: 210]
d1k0wa_ : (GLU3) (SER60) [view usage] : c.74.1.1 |AraD/HMP-PK domain-like |AraD/HMP-PK domain-like |AraD-like aldolase/epimerase |L-ribulose-5-phosphate 4-epimerase |Escherichia coli [TaxId: 562]
d3uida_ : (PRO35) (ILE80) [view usage] : d.129.3.0 |TBP-like |Bet v1-like |automated matches |automated matches |Mycobacterium smegmatis [TaxId: 246196]
d1kafd_ : (SER108) (ASN156) [view usage] : d.199.1.1 |MotA C-terminal domain-like |DNA-binding C-terminal domain of the transcription factor MotA |DNA-binding C-terminal domain of the transcription factor MotA |DNA-binding C-terminal domain of the transcription factor MotA |Bacteriophage T4 [TaxId: 10665]
d2pt7a_ : (PHE36) (ASP69) [view usage] : c.37.1.11 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |RecA protein-like (ATPase-domain) |Hexameric traffic ATPase, HP0525 |Helicobacter pylori [TaxId: 210]
d2fwlb_ : (TYR90) (PRO129) [view usage] : b.6.1.2 |Cupredoxin-like |Cupredoxins |Periplasmic domain of cytochrome c oxidase subunit II |Cytochrome c oxidase |Thermus thermophilus, ba3 type [TaxId: 274]
d1nlzb_ : (PHE36) (ASP69) [view usage] : c.37.1.11 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |RecA protein-like (ATPase-domain) |Hexameric traffic ATPase, HP0525 |Helicobacter pylori [TaxId: 210]
d3ibra1 : (GLU67) (ALA115) [view usage] : d.110.3.9 |Profilin-like |PYP-like sensor domain (PAS domain) |BphP N-terminal domain-like |Bacteriophytochrome BphP |Pseudomonas aeruginosa [TaxId: 287]
d1ni5a4 : (ASP273) (ILE310) [view usage] : d.229.1.1 |MesJ substrate recognition domain-like |MesJ substrate recognition domain-like |MesJ substrate recognition domain-like |tRNA-Ile-lysidine synthetase, TilS, substrate-binding domain |Escherichia coli [TaxId: 562]
d2iuha_ : (SER18) (ARG65) [view usage] : d.93.1.1 |SH2-like |SH2 domain |SH2 domain |automated matches |Human (Homo sapiens) [TaxId: 9606]
d1nj1a3 : (ALA176) (ASN238) [view usage] : d.104.1.1 |Class II aaRS and biotin synthetases |Class II aaRS and biotin synthetases |Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain |Prolyl-tRNA synthetase (ProRS) |Methanothermobacter thermautotrophicus [TaxId: 145262]
d2e11a_ : (ALA180) (ARG231) [view usage] : d.160.1.0 |Carbon-nitrogen hydrolase |Carbon-nitrogen hydrolase |automated matches |automated matches |Xanthomonas campestris pv. campestris [TaxId: 340]
d2fb5b_ : (THR166) (LEU205) [view usage] : d.320.1.1 |YojJ-like |YojJ-like |YojJ-like |Hypothetical protein BC4920 (YojJ) |Bacillus cereus [TaxId: 1396]
d1f5aa4 : (SER132) (ALA174) [view usage] : d.218.1.3 |Nucleotidyltransferase |Nucleotidyltransferase |Poly(A) polymerase, PAP, N-terminal domain |Poly(A) polymerase, PAP, N-terminal domain |Cow (Bos taurus) [TaxId: 9913]
d4ok9a_ : (TYR70) (ASN147) [view usage] : d.275.1.1 |Hut operon positive regulatory protein HutP |Hut operon positive regulatory protein HutP |Hut operon positive regulatory protein HutP |automated matches |Geobacillus thermodenitrificans [TaxId: 420246]
List of distinct SCOP folds where this concept is used (in one or more of its domains):
c.1, c.2, c.56, c.14, d.129, c.74, d.144, c.37, d.104, d.169, d.194, d.81, d.248, b.6, e.7, d.160, d.110, d.124, d.106, c.52,
d.93, d.218, d.298, d.198, d.317, d.156, d.36, d.199, d.387, d.229, d.275, d.40, d.320