Protein Concepts Dictionary

Tableau information

Concept source:  d1w1ha_  amino acid (a.a.) range (LEU504)(GLN548)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: EEEH

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (LEU504)  (ASN510) E1
	  (LYS512)  (THR518) E2
	  (ARG521)  (ASP527) E3
	  (ALA532)  (GLN548) H4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          E1                          
E2      160.5°   E2                   
E3      -38.5°  160.9°   E3            
H4     -158.2°   27.2°  137.6°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±9.1°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d2mi6a_ :    (SER30)   (SER60)   [view usage] : b.34.5.0 |SH3-like barrel |Translation proteins SH3-like domain |automated matches |automated matches |Mycobacterium tuberculosis [TaxId: 1773]
 d2fz4a1 :    (ILE24)   (GLY72)   [view usage] : c.37.1.19 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |Tandem AAA-ATPase domain |DNA repair protein RAD25 |Archaeoglobus fulgidus [TaxId: 2234]
 d2yrya_ :    (SER70)  (ARG120)   [view usage] : b.55.1.0 |PH domain-like barrel |PH domain-like |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d2gjya_ :    (THR76)  (MET137)   [view usage] : b.55.1.2 |PH domain-like barrel |PH domain-like |Phosphotyrosine-binding domain (PTB) |automated matches |Chicken (Gallus gallus) [TaxId: 9031]
 d2g9fa1 :   (GLN489)  (VAL518)   [view usage] : b.18.1.29 |Galactose-binding domain-like |Galactose-binding domain-like |Extended PAW domain |Peptide:N-glycanase, PNGase, C-terminal domain |Mouse (Mus musculus) [TaxId: 10090]
 d4it1b1 :     (SER0)   (ILE66)   [view usage] : d.54.1.0 |Enolase N-terminal domain-like |Enolase N-terminal domain-like |automated matches |automated matches |Pseudomonas fluorescens [TaxId: 205922]
 d1d9na_ :    (TRP15)   (GLY54)   [view usage] : d.10.1.3 |DNA-binding domain |DNA-binding domain |Methyl-CpG-binding domain, MBD |Methylation-dependent transcriptional repressor MBD1/PCM1 |Human (Homo sapiens) [TaxId: 9606]
 d1upqa_ :   (SER103)  (ARG153)   [view usage] : b.55.1.1 |PH domain-like barrel |PH domain-like |Pleckstrin-homology domain (PH domain) |Phosphoinositol 3-phosphate binding protein-1, PEPP1 |Human (Homo sapiens) [TaxId: 9606]
 d1fhoa_ :    (ASN63)  (GLU109)   [view usage] : b.55.1.1 |PH domain-like barrel |PH domain-like |Pleckstrin-homology domain (PH domain) |UNC-89 |Nematode (Caenorhabditis elegans) [TaxId: 6239]
 d3dcxa1 :    (THR75)  (LEU124)   [view usage] : b.55.1.13 |PH domain-like barrel |PH domain-like |BPHL domain |Uncharacterized protein Shew0819 |Shewanella loihica [TaxId: 359303]
 d2pyjb1 :     (HIS3)   (LYS53)   [view usage] : c.55.3.5 |Ribonuclease H-like motif |Ribonuclease H-like |DnaQ-like 3'-5' exonuclease |Exonuclease domain of phi29 DNA polymerase |Bacteriophage phi-29 [TaxId: 10756]
 d1qqgb1 :    (ARG14)   (LYS56)   [view usage] : b.55.1.2 |PH domain-like barrel |PH domain-like |Phosphotyrosine-binding domain (PTB) |Insulin receptor substrate 1, IRS-1 |Human (Homo sapiens) [TaxId: 9606]
 d2a6aa2 :   (VAL106)  (GLU149)   [view usage] : c.55.1.9 |Ribonuclease H-like motif |Actin-like ATPase domain |YeaZ-like |Hypothetical protein TM0874 |Thermotoga maritima [TaxId: 2336]
 d1g8ma2 :   (SER203)  (ASP243)   [view usage] : c.97.1.4 |Cytidine deaminase-like |Cytidine deaminase-like |AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC |AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC |Chicken (Gallus gallus) [TaxId: 9031]
 d1v5ra1 :    (LYS44)   (ASP75)   [view usage] : d.82.4.1 |N domain of copper amine oxidase-like |GAS2 domain-like |GAS2 domain |Growth-arrest-specific protein 2, GAS2 |Mouse (Mus musculus) [TaxId: 10090]
 d2xqnm_ :    (GLY67)  (ASN112)   [view usage] : b.55.1.4 |PH domain-like barrel |PH domain-like |Enabled/VASP homology 1 domain (EVH1 domain) |Enabled |Human (Homo sapiens) [TaxId: 9606]
 d1et6a1 :    (ASP26)   (ASN58)   [view usage] : b.40.2.2 |OB-fold |Bacterial enterotoxins |Superantigen toxins, N-terminal domain |Streptococcal superantigen Smez-2 |Streptococcus pyogenes [TaxId: 1314]
 d1zsqa1 :   (ASN133)  (PRO185)   [view usage] : b.55.1.8 |PH domain-like barrel |PH domain-like |GRAM domain |Myotubularin-related protein 2, N-terminal domain |Human (Homo sapiens) [TaxId: 9606]
 d2a6ab2 :   (VAL106)  (GLU149)   [view usage] : c.55.1.9 |Ribonuclease H-like motif |Actin-like ATPase domain |YeaZ-like |Hypothetical protein TM0874 |Thermotoga maritima [TaxId: 2336]
 d2p97a1 :     (ASP8)   (GLY54)   [view usage] : d.157.1.12 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |Ava3068-like |Hypothetical protein Ava3068 |Anabaena variabilis [TaxId: 1172]
 d2jp2a_ :    (ASP80)  (GLU126)   [view usage] : b.55.1.0 |PH domain-like barrel |PH domain-like |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d4it1a1 :     (SER0)   (LEU65)   [view usage] : d.54.1.0 |Enolase N-terminal domain-like |Enolase N-terminal domain-like |automated matches |automated matches |Pseudomonas fluorescens [TaxId: 205922]
 d2ys1a_ :    (ASN57)  (GLY112)   [view usage] : b.55.1.1 |PH domain-like barrel |PH domain-like |Pleckstrin-homology domain (PH domain) |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d4it1d1 :     (SER0)   (ILE66)   [view usage] : d.54.1.0 |Enolase N-terminal domain-like |Enolase N-terminal domain-like |automated matches |automated matches |Pseudomonas fluorescens [TaxId: 205922]
 d1r4pb_ :     (GLU9)   (LEU44)   [view usage] : b.40.2.1 |OB-fold |Bacterial enterotoxins |Bacterial AB5 toxins, B-subunits |Verotoxin-1/shiga-toxin, B-pentamer |Shigella dysenteriae, toxin II [TaxId: 622]
 d1wgqa_ :    (GLY55)  (VAL103)   [view usage] : b.55.1.1 |PH domain-like barrel |PH domain-like |Pleckstrin-homology domain (PH domain) |FYVE, RhoGEF and PH domain containing protein 6, Fgd6 (KIAA1362) |Mouse (Mus musculus) [TaxId: 10090]
 d2f3ia_ :    (GLU89)  (HIS133)   [view usage] : b.40.4.0 |OB-fold |Nucleic acid-binding proteins |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d3mxga_ :     (GLU9)   (LEU44)   [view usage] : b.40.2.1 |OB-fold |Bacterial enterotoxins |Bacterial AB5 toxins, B-subunits |automated matches |Escherichia coli O157:H7 [TaxId: 83334]
 d1ktkc1 :    (ASN30)   (LYS62)   [view usage] : b.40.2.2 |OB-fold |Bacterial enterotoxins |Superantigen toxins, N-terminal domain |Streptococcal superantigen Spe-C |Streptococcus pyogenes [TaxId: 1314]
 d2hc5a1 :    (HIS57)  (VAL105)   [view usage] : d.352.1.1 |FlaG-like |FlaG-like |FlaG-like |Hypothetical protein YvyC |Bacillus subtilis [TaxId: 1423]
 d3r9ya_ :   (GLN150)  (GLY208)   [view usage] : d.18.1.0 |ssDNA-binding transcriptional regulator domain |ssDNA-binding transcriptional regulator domain |automated matches |automated matches |Potato (Solanum tuberosum) [TaxId: 4113]
 d1x05a1 :    (VAL73)  (ARG120)   [view usage] : b.55.1.1 |PH domain-like barrel |PH domain-like |Pleckstrin-homology domain (PH domain) |Pleckstrin |Human (Homo sapiens) [TaxId: 9606]
 d1akoa_ :    (ASN53)   (ARG90)   [view usage] : d.151.1.1 |DNase I-like |DNase I-like |DNase I-like |DNA-repair enzyme exonuclease III |Escherichia coli [TaxId: 562]
 d1qqga1 :    (ARG14)   (LYS56)   [view usage] : b.55.1.2 |PH domain-like barrel |PH domain-like |Phosphotyrosine-binding domain (PTB) |Insulin receptor substrate 1, IRS-1 |Human (Homo sapiens) [TaxId: 9606]
 d2bi0a1 :   (VAL116)  (ALA177)   [view usage] : d.38.1.4 |Thioesterase/thiol ester dehydrase-isomerase |Thioesterase/thiol ester dehydrase-isomerase |MaoC-like |Hypothetical protein Rv0216/MT0226 |Mycobacterium tuberculosis [TaxId: 1773]
 d1r79a_ :    (PRO27)   (LEU74)   [view usage] : g.49.1.1 |Cysteine-rich domain |Cysteine-rich domain |Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) |Diacylglycerol kinase delta |Human (Homo sapiens) [TaxId: 9606]
 d1baka_ :   (VAL609)  (VAL658)   [view usage] : b.55.1.1 |PH domain-like barrel |PH domain-like |Pleckstrin-homology domain (PH domain) |G-protein coupled receptor kinase 2 (beta-adrenergic receptor kinase 1) |Human (Homo sapiens) [TaxId: 9606]
 d1bpxa4 :   (GLY290)  (ASP321)   [view usage] : d.218.1.2 |Nucleotidyltransferase |Nucleotidyltransferase |DNA polymerase beta-like |DNA polymerase beta, catalytic (31 kD) fragment |Human (Homo sapiens) [TaxId: 9606]
 d2wwea_ :  (GLU1205) (GLN1251)   [view usage] : d.189.1.0 |PX domain |PX domain |automated matches |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1v5ma_ :    (ILE81)  (SER131)   [view usage] : b.55.1.1 |PH domain-like barrel |PH domain-like |Pleckstrin-homology domain (PH domain) |SH2 and PH domain-containing adapter protein APS |Mouse (Mus musculus) [TaxId: 10090]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
 d.157,    b.40,    c.37,    c.55,   d.151,    b.18,    c.97,    d.38,    b.55,    b.34,   d.218,    d.54,    d.82,    d.18,   d.189,    d.10,   d.352,    g.49