Protein Concepts Dictionary

Tableau information

Concept source:  d2k01a_  amino acid (a.a.) range (HIS25)(LEU66)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: EEEH

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	   (HIS25)   (THR31) E1
	   (CYS36)   (LEU42) E2
	   (ARG47)   (ASP52) E3
	   (LYS56)   (LEU66) H4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          E1                          
E2      152.1°   E2                   
E3      -54.2°  151.5°   E3            
H4      -90.7°  100.5°  -84.8°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±12.7°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d3e66a1 :  (VAL1857) (GLN1902)   [view usage] : c.55.3.14 |Ribonuclease H-like motif |Ribonuclease H-like |Prp8 beta-finger domain-like |Pre-mRNA-splicing factor 8, Prp8 |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d3hp3a_ :    (LEU26)   (GLU63)   [view usage] : d.9.1.1 |IL8-like |Interleukin 8-like chemokines |Interleukin 8-like chemokines |Stromal cell-derived factor-1 (SDF-1) |Human (Homo sapiens) [TaxId: 9606]
 d1u74c_ :   (GLU209)  (ASP241)   [view usage] : a.93.1.1 |Heme-dependent peroxidases |Heme-dependent peroxidases |CCP-like |Cytochrome c peroxidase, CCP |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d4g9ja_ :   (TRP206)  (HIS239)   [view usage] : d.159.1.3 |Metallo-dependent phosphatases |Metallo-dependent phosphatases |Protein serine/threonine phosphatase |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1d5mc2 :   (LYS128)  (LYS173)   [view usage] : d.15.6.1 |beta-Grasp (ubiquitin-like) |Superantigen toxins, C-terminal domain |Superantigen toxins, C-terminal domain |Staphylococcal enterotoxin B, SEB |Staphylococcus aureus [TaxId: 1280]
 d1vaza_ :     (GLY7)   (GLY46)   [view usage] : d.245.1.1 |NSFL1 (p97 ATPase) cofactor p47, SEP domain |NSFL1 (p97 ATPase) cofactor p47, SEP domain |NSFL1 (p97 ATPase) cofactor p47, SEP domain |NSFL1 (p97 ATPase) cofactor p47, SEP domain |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d3e9oa1 :  (VAL1857) (GLN1902)   [view usage] : c.55.3.14 |Ribonuclease H-like motif |Ribonuclease H-like |Prp8 beta-finger domain-like |Pre-mRNA-splicing factor 8, Prp8 |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1xdoa4 :   (ASP593)  (ASP647)   [view usage] : d.136.1.4 |Phospholipase D/nuclease |Phospholipase D/nuclease |Polyphosphate kinase C-terminal domain |Polyphosphate kinase, PPK |Escherichia coli [TaxId: 562]
 d1v1oa2 :   (SER112)  (GLY160)   [view usage] : d.15.6.1 |beta-Grasp (ubiquitin-like) |Superantigen toxins, C-terminal domain |Superantigen toxins, C-terminal domain |Exotoxin 1 (SET1, Superantigen-like protein 7) |Staphylococcus aureus [TaxId: 1280]
 d1tfoa_ :   (SER655)  (GLU693)   [view usage] : d.243.1.1 |Colicin D/E5 nuclease domain |Colicin D/E5 nuclease domain |Colicin D nuclease domain |Colicin D nuclease domain |Escherichia coli [TaxId: 562]
 d3shda_ :     (PHE2)   (GLU55)   [view usage] : d.113.1.0 |Nudix |Nudix |automated matches |automated matches |Escherichia coli [TaxId: 405955]
 d3hp3e_ :    (LYS24)   (GLU63)   [view usage] : d.9.1.1 |IL8-like |Interleukin 8-like chemokines |Interleukin 8-like chemokines |Stromal cell-derived factor-1 (SDF-1) |Human (Homo sapiens) [TaxId: 9606]
 d1d5xc2 :   (LYS128)  (LYS173)   [view usage] : d.15.6.1 |beta-Grasp (ubiquitin-like) |Superantigen toxins, C-terminal domain |Superantigen toxins, C-terminal domain |Staphylococcal enterotoxin B, SEB |Staphylococcus aureus [TaxId: 1280]
 d1ilr2_ :    (ALA55)   (ALA99)   [view usage] : b.42.1.2 |beta-Trefoil |Cytokine |Interleukin-1 (IL-1) |Interleukin-1 receptor antagonist protein |Human (Homo sapiens) [TaxId: 9606]
 d1e8ma1 :     (VAL9)   (PRO34)   [view usage] : b.69.7.1 |7-bladed beta-propeller |Peptidase/esterase 'gauge' domain |Prolyl oligopeptidase, N-terminal domain |Prolyl oligopeptidase, N-terminal domain |Pig (Sus scrofa) [TaxId: 9823]
 d3bpnb1 :    (ASP66)   (VAL96)   [view usage] : b.1.2.1 |Immunoglobulin-like beta-sandwich |Fibronectin type III |Fibronectin type III |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1nc7d_ :    (THR37)   (GLY72)   [view usage] : b.123.1.1 |Hypothetical protein TM1070 |Hypothetical protein TM1070 |Hypothetical protein TM1070 |Hypothetical protein TM1070 |Thermotoga maritima [TaxId: 2336]
 d1ep5a_ :   (LYS126)  (LEU165)   [view usage] : b.47.1.3 |Trypsin-like serine proteases |Trypsin-like serine proteases |Viral proteases |Viral capsid protein |Venezuelan equine encephalitis virus [TaxId: 11036]
 d1uwwa_ :    (TYR88)  (LEU133)   [view usage] : b.18.1.23 |Galactose-binding domain-like |Galactose-binding domain-like |Family 28 carbohydrate binding module, CBM28 |Endoglucanase (alkaline cellulase) |Bacillus sp. 1139 [TaxId: 1411]
 d1wgea1 :    (PHE20)   (GLY49)   [view usage] : g.41.17.1 |Rubredoxin-like |CSL zinc finger |CSL zinc finger |DelGEF-interacting protein 1, DelGIP1 |Mouse (Mus musculus) [TaxId: 10090]
 d3sbpa1 :   (LEU381)  (GLY415)   [view usage] : b.69.3.1 |7-bladed beta-propeller |Nitrous oxide reductase, N-terminal domain |Nitrous oxide reductase, N-terminal domain |automated matches |Pseudomonas stutzeri [TaxId: 316]
 d1pv4b1 :    (VAL54)   (PHE89)   [view usage] : b.40.4.5 |OB-fold |Nucleic acid-binding proteins |Cold shock DNA-binding domain-like |Rho termination factor, RNA-binding domain |Escherichia coli [TaxId: 562]
 d2r3za_ :    (GLY25)   (PHE68)   [view usage] : d.9.1.1 |IL8-like |Interleukin 8-like chemokines |Interleukin 8-like chemokines |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d1wj1a_ :    (ALA64)   (SER93)   [view usage] : b.55.1.2 |PH domain-like barrel |PH domain-like |Phosphotyrosine-binding domain (PTB) |Numb |Mouse (Mus musculus) [TaxId: 10090]
 d1ep6c_ :   (LYS126)  (LEU165)   [view usage] : b.47.1.3 |Trypsin-like serine proteases |Trypsin-like serine proteases |Viral proteases |Viral capsid protein |Venezuelan equine encephalitis virus [TaxId: 11036]
 d3hp3f_ :    (LYS24)   (LYS64)   [view usage] : d.9.1.1 |IL8-like |Interleukin 8-like chemokines |Interleukin 8-like chemokines |Stromal cell-derived factor-1 (SDF-1) |Human (Homo sapiens) [TaxId: 9606]
 d3hp3b_ :    (LYS24)   (LEU62)   [view usage] : d.9.1.1 |IL8-like |Interleukin 8-like chemokines |Interleukin 8-like chemokines |Stromal cell-derived factor-1 (SDF-1) |Human (Homo sapiens) [TaxId: 9606]
 d3sw1a_ :    (ARG80)  (ALA134)   [view usage] : d.110.3.0 |Profilin-like |PYP-like sensor domain (PAS domain) |automated matches |automated matches |Pseudomonas putida [TaxId: 160488]
 d1uxbb_ :   (ASN195)  (ILE233)   [view usage] : b.21.1.1 |Virus attachment protein globular domain |Virus attachment protein globular domain |Adenovirus fiber protein "knob" domain |Adenovirus fiber protein "knob" domain |Human adenovirus 37 [TaxId: 52275]
 d2lbha_ :    (LYS18)   (PRO51)   [view usage] : b.9.1.1 |Neurophysin II |Neurophysin II |Neurophysin II |Neurophysin II |Cow (Bos taurus) [TaxId: 9913]
 d2k01a_ :    (HIS25)   (LEU66)   [view usage] : d.9.1.1 |IL8-like |Interleukin 8-like chemokines |Interleukin 8-like chemokines |Stromal cell-derived factor-1 (SDF-1) |Human (Homo sapiens) [TaxId: 9606]
 d1ivpa_ :    (GLU63)   (LEU93)   [view usage] : b.50.1.1 |Acid proteases |Acid proteases |Retroviral protease (retropepsin) |Human immunodeficiency virus type 2 (HIV-2) protease |Human immunodeficiency virus type 2 [TaxId: 11709]
 d1dyla_ :   (CYS119)  (LEU158)   [view usage] : i.6.1.1 |Viruses and virus-receptor complexes |Viruses and virus-receptor complexes |Viruses and virus-receptor complexes |SFV capsid |Semliki forest virus [TaxId: 11033]
 d1y8ba_ :   (VAL189)  (VAL217)   [view usage] : c.1.13.1 |TIM beta/alpha-barrel |Malate synthase G |Malate synthase G |Malate synthase G |Escherichia coli [TaxId: 562]
 d1g63b_ :   (VAL138)  (VAL172)   [view usage] : c.34.1.1 |Homo-oligomeric flavin-containing Cys decarboxylases, HFCD |Homo-oligomeric flavin-containing Cys decarboxylases, HFCD |Homo-oligomeric flavin-containing Cys decarboxylases, HFCD |Epidermin modifying enzyme (peptidyl-cysteine decarboxylase) EpiD |Staphylococcus epidermidis [TaxId: 1282]
 d1tfka_ :   (SER655)  (GLY695)   [view usage] : d.243.1.1 |Colicin D/E5 nuclease domain |Colicin D/E5 nuclease domain |Colicin D nuclease domain |Colicin D nuclease domain |Escherichia coli [TaxId: 562]
 d2ks4a_ :    (GLY96)  (ASN139)   [view usage] : b.97.1.1 |Cytolysin/lectin |Cytolysin/lectin |Anemone pore-forming cytolysin |automated matches |Sea anemone (Stichodactyla helianthus) [TaxId: 6123]
 d3lida2 :   (ALA263)  (ARG300)   [view usage] : d.110.6.2 |Profilin-like |Sensory domain-like |YkuI C-terminal domain-like |GGDEF family protein VP0354 |Vibrio parahaemolyticus [TaxId: 670]
 d4lmqf_ :    (HIS25)   (LYS64)   [view usage] : d.9.1.1 |IL8-like |Interleukin 8-like chemokines |Interleukin 8-like chemokines |Stromal cell-derived factor-1 (SDF-1) |Human (Homo sapiens) [TaxId: 9606]
 d3hp3j_ :    (LYS24)   (LYS64)   [view usage] : d.9.1.1 |IL8-like |Interleukin 8-like chemokines |Interleukin 8-like chemokines |Stromal cell-derived factor-1 (SDF-1) |Human (Homo sapiens) [TaxId: 9606]
 d4b7qa_ :   (GLY348)  (THR383)   [view usage] : b.68.1.0 |6-bladed beta-propeller |Sialidases |automated matches |automated matches |Influenza a virus (a/california/07/2009(h1n1)) [TaxId: 641809]
 d2g43b_ :    (PRO82)  (GLY119)   [view usage] : g.44.1.5 |RING/U-box |RING/U-box |Zf-UBP |Ubiquitin carboxyl-terminal hydrolase 5, UBP5 |Human (Homo sapiens) [TaxId: 9606]
 d2o8aa_ :   (TRP206)  (ASP240)   [view usage] : d.159.1.3 |Metallo-dependent phosphatases |Metallo-dependent phosphatases |Protein serine/threonine phosphatase |Protein phosphatase-1 (PP-1) |Norway rat (Rattus norvegicus) [TaxId: 10116]
 d1u74a_ :   (GLU209)  (ASP241)   [view usage] : a.93.1.1 |Heme-dependent peroxidases |Heme-dependent peroxidases |CCP-like |Cytochrome c peroxidase, CCP |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1hu9a1 :   (SER444)  (ARG535)   [view usage] : a.119.1.1 |Lipoxigenase |Lipoxigenase |Plant lipoxigenases |Lipoxigenase, C-terminal domain |Soybean (Glycine max), isozyme L3 [TaxId: 3847]
 d2ygta_ :   (TYR152)  (GLY222)   [view usage] : f.6.1.0 |Leukocidin-like |Leukocidin-like |automated matches |automated matches |Clostridium perfringens [TaxId: 1502]
 d1ep5c_ :   (THR127)  (LEU165)   [view usage] : b.47.1.3 |Trypsin-like serine proteases |Trypsin-like serine proteases |Viral proteases |Viral capsid protein |Venezuelan equine encephalitis virus [TaxId: 11036]
 d1f8na1 :   (SER425)  (LEU518)   [view usage] : a.119.1.1 |Lipoxigenase |Lipoxigenase |Plant lipoxigenases |Lipoxigenase, C-terminal domain |Soybean (Glycine max), isozyme L1 [TaxId: 3847]
 d2iuka2 :   (THR451)  (LEU544)   [view usage] : a.119.1.1 |Lipoxigenase |Lipoxigenase |Plant lipoxigenases |automated matches |Soybean (Glycine max) [TaxId: 3847]
 d1xo0a2 :   (ILE185)  (GLY229)   [view usage] : d.163.1.1 |DNA breaking-rejoining enzymes |DNA breaking-rejoining enzymes |Lambda integrase-like, catalytic core |Cre recombinase |Bacteriophage P1 [TaxId: 10678]
 d1pvpa2 :   (ASP184)  (VAL227)   [view usage] : d.163.1.1 |DNA breaking-rejoining enzymes |DNA breaking-rejoining enzymes |Lambda integrase-like, catalytic core |Cre recombinase |Bacteriophage P1 [TaxId: 10678]
 d1xx8a_ :    (LYS21)   (LYS66)   [view usage] : b.34.13.1 |SH3-like barrel |Chromo domain-like |"Histone-like" proteins from archaea |automated matches |Sulfolobus acidocaldarius [TaxId: 2285]
 d1qqrb_ :   (LYS156)  (ASN210)   [view usage] : d.15.5.1 |beta-Grasp (ubiquitin-like) |Staphylokinase/streptokinase |Staphylokinase/streptokinase |Streptokinase |Streptococcus equisimilis [TaxId: 119602]
 d1bd7a_ :    (HIS88)  (GLY117)   [view usage] : b.11.1.1 |gamma-Crystallin-like |gamma-Crystallin-like |Crystallins/Ca-binding development proteins |beta-Crystallin |Norway rat (Rattus norvegicus), isoform E [TaxId: 10116]
 d2nwgb_ :    (HIS25)   (ASN67)   [view usage] : d.9.1.1 |IL8-like |Interleukin 8-like chemokines |Interleukin 8-like chemokines |Stromal cell-derived factor-1 (SDF-1) |Human (Homo sapiens) [TaxId: 9606]
 d1vmca_ :    (HIS25)   (LYS68)   [view usage] : d.9.1.1 |IL8-like |Interleukin 8-like chemokines |Interleukin 8-like chemokines |Stromal cell-derived factor-1 (SDF-1) |Human (Homo sapiens) [TaxId: 9606]
 d1baia_ :    (GLU81)  (GLY118)   [view usage] : b.50.1.1 |Acid proteases |Acid proteases |Retroviral protease (retropepsin) |Rous sarcoma virus protease |Rous sarcoma virus, strain pr-C [TaxId: 11886]
 d2erma_ :    (PRO25)   (ILE56)   [view usage] : b.42.1.1 |beta-Trefoil |Cytokine |Fibroblast growth factors (FGF) |Acidic FGF (FGF1) |Human (Homo sapiens) [TaxId: 9606]
 d1sdfa_ :    (HIS25)   (ASN67)   [view usage] : d.9.1.1 |IL8-like |Interleukin 8-like chemokines |Interleukin 8-like chemokines |Stromal cell-derived factor-1 (SDF-1) |Human (Homo sapiens) [TaxId: 9606]
 d2iuja2 :   (THR439)  (HIS531)   [view usage] : a.119.1.1 |Lipoxigenase |Lipoxigenase |Plant lipoxigenases |automated matches |Soybean (Glycine max) [TaxId: 3847]
 d1v1pa2 :   (THR109)  (GLY158)   [view usage] : d.15.6.1 |beta-Grasp (ubiquitin-like) |Superantigen toxins, C-terminal domain |Superantigen toxins, C-terminal domain |Exotoxin 1 (SET1, Superantigen-like protein 7) |Staphylococcus aureus [TaxId: 1280]
 d1wfva_ :    (PHE13)   (GLY53)   [view usage] : b.36.1.1 |PDZ domain-like |PDZ domain-like |PDZ domain |Membrane associated guanylate kinase inverted-2 (MAGI-2, KIAA0705) |Human (Homo sapiens) [TaxId: 9606]
 d1nlze_ :    (THR46)   (SER77)   [view usage] : c.37.1.11 |P-loop containing nucleoside triphosphate hydrolases |P-loop containing nucleoside triphosphate hydrolases |RecA protein-like (ATPase-domain) |Hexameric traffic ATPase, HP0525 |Helicobacter pylori [TaxId: 210]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  b.68,     c.1,   a.119,   d.159,    b.69,    b.47,    a.93,    b.50,     i.6,    b.40,    c.37,    c.55,    b.18,     b.1,   d.110,    b.42,    b.21,    b.55,    b.34,    b.11,  
b.97, c.34, d.15, d.113, d.136, b.36, b.123, d.9, g.41, f.6, g.44, d.163, d.245, d.243, b.9