Protein Concepts Dictionary

Tableau information

Concept source:  d1r27a2  amino acid (a.a.) range (GLU425)(THR472)

nSSEs in this Concept: 4

String of secondary struct.elems. (SSEs) defining this concept: EEEE

Each SSE's a.a.range: (start resi) (end resi) SSEtype (H=Helix; E=Strand) followed by a numeric SSE ID:
	  (GLU425)  (PHE434) E1
	  (ASN449)  (LYS454) E2
	  (PRO456)  (GLN461) E3
	  (ALA468)  (THR472) E4

Orientation angles° of SSE-pairs; those in contact shown in bold font
          E1                          
E2      158.0°   E2                   
E3      112.9°  -79.5°   E3            
E4      -65.6°   93.1°  140.9°       
Footnote: Inferred from this concept's usages (listed below) was the angular variance of 1σ = ±13.0°  about each orientation angle shown above.

Loci of concept usages (shown as a range of a.a. residue ids) in SCOP(v2.05) domains, along with their brief legend taken from SCOP
 d2cr2a1 :    (SER76)  (GLY112)   [view usage] : b.8.1.1 |TRAF domain-like |TRAF domain-like |MATH domain |Speckle-type poz protein SPOP |Human (Homo sapiens) [TaxId: 9606]
 d1te0a2 :    (ASN60)   (ASN94)   [view usage] : b.47.1.1 |Trypsin-like serine proteases |Trypsin-like serine proteases |Prokaryotic proteases |Stress sensor protease DegS, catalytic domain |Escherichia coli [TaxId: 562]
 d1vcla2 :   (GLY205)  (ASN248)   [view usage] : b.42.2.1 |beta-Trefoil |Ricin B-like lectins |Ricin B-like |Hemolytic lectin CEL-III, domains 1 and 2 |Cucumaria echinata [TaxId: 40245]
 d3r7ka1 :   (THR160)  (ALA190)   [view usage] : e.6.1.0 |Acyl-CoA dehydrogenase NM domain-like |Acyl-CoA dehydrogenase NM domain-like |automated matches |automated matches |Mycobacterium abscessus [TaxId: 561007]
 d1z5fa_ :    (ASP61)  (GLY100)   [view usage] : d.5.1.1 |RNase A-like |RNase A-like |Ribonuclease A-like |automated matches |Bullfrog (Rana catesbeiana) [TaxId: 8400]
 d2e4ma1 :    (VAL26)   (VAL63)   [view usage] : b.42.2.1 |beta-Trefoil |Ricin B-like lectins |Ricin B-like |automated matches |Clostridium botulinum [TaxId: 1491]
 d3n7ka2 :  (CYS1245) (PRO1288)   [view usage] : b.42.4.0 |beta-Trefoil |STI-like |automated matches |automated matches |Clostridium botulinum [TaxId: 1491]
 d1qxma1 :    (VAL26)   (VAL63)   [view usage] : b.42.2.1 |beta-Trefoil |Ricin B-like lectins |Ricin B-like |Hemagglutinin component Ha1 |Clostridium botulinum D phage [TaxId: 29342]
 d2vina_ :    (ALA32)   (ALA55)   [view usage] : b.47.1.2 |Trypsin-like serine proteases |Trypsin-like serine proteases |Eukaryotic proteases |automated matches |Human (Homo sapiens) [TaxId: 9606]
 d1lvba_ :    (GLY53)   (ARG86)   [view usage] : b.47.1.3 |Trypsin-like serine proteases |Trypsin-like serine proteases |Viral proteases |TEV protease (nucleat inclusion protein A, NIA) |Tobacco etch virus, TEV [TaxId: 12227]
 d1v9za_ :    (ARG97)  (VAL130)   [view usage] : d.110.3.2 |Profilin-like |PYP-like sensor domain (PAS domain) |Heme-binding PAS domain |Direct oxygen sensor protein, DOS |Escherichia coli [TaxId: 562]
 d1usca_ :    (VAL20)   (SER53)   [view usage] : b.45.1.2 |Split barrel-like |FMN-binding split barrel |NADH:FMN oxidoreductase-like |Putative styrene monooxygenase small component |Thermus thermophilus [TaxId: 274]
 d1vb6a_ :    (ARG97)  (VAL130)   [view usage] : d.110.3.2 |Profilin-like |PYP-like sensor domain (PAS domain) |Heme-binding PAS domain |Direct oxygen sensor protein, DOS |Escherichia coli [TaxId: 562]
 d1soza2 :    (VAL61)   (ASN94)   [view usage] : b.47.1.1 |Trypsin-like serine proteases |Trypsin-like serine proteases |Prokaryotic proteases |Stress sensor protease DegS, catalytic domain |Escherichia coli [TaxId: 562]
 d1r27a2 :   (GLU425)  (THR472)   [view usage] : c.81.1.1 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Respiratory nitrate reductase 1 alpha chain |Escherichia coli [TaxId: 562]
 d1i10a2 :   (THR274)  (THR306)   [view usage] : d.162.1.1 |LDH C-terminal domain-like |LDH C-terminal domain-like |Lactate & malate dehydrogenases, C-terminal domain |Lactate dehydrogenase |Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]
 d3lgib_ :    (ASN60)   (ASN94)   [view usage] : b.47.1.1 |Trypsin-like serine proteases |Trypsin-like serine proteases |Prokaryotic proteases |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d1iwoa1 :   (LYS128)  (ALA161)   [view usage] : b.82.7.1 |Double-stranded beta-helix |Calcium ATPase, transduction domain A |Calcium ATPase, transduction domain A |Calcium ATPase, transduction domain A |Rabbit (Oryctolagus cuniculus) [TaxId: 9986]
 d3mmga_ :    (GLU54)   (LYS86)   [view usage] : b.47.1.0 |Trypsin-like serine proteases |Trypsin-like serine proteases |automated matches |automated matches |Tobacco vein mottling virus [TaxId: 12228]
 d1vkda_ :   (TRP226)  (TYR263)   [view usage] : b.67.2.4 |5-bladed beta-propeller |Arabinanase/levansucrase/invertase |TM1225-like predicted glycosylases |Hypothetical protein TM1225 |Thermotoga maritima [TaxId: 2336]
 d3c2ua1 :   (GLN258)  (VAL307)   [view usage] : b.67.2.0 |5-bladed beta-propeller |Arabinanase/levansucrase/invertase |automated matches |automated matches |Selenomonas ruminantium [TaxId: 971]
 d3zbwa_ :    (GLN76)  (SER117)   [view usage] : d.5.1.1 |RNase A-like |RNase A-like |Ribonuclease A-like |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d3tewa1 :   (GLY641)  (ASP677)   [view usage] : f.60.1.1 |Anthrax protective antigen C-terminal-like |Anthrax protective antigen C-terminal-like |Anthrax protective antigen C-terminal-like |Anthrax protective antigen C-terminal-like |Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]
 d1j7xa_ :   (HIS244)  (GLY274)   [view usage] : c.14.1.2 |ClpP/crotonase |ClpP/crotonase |Tail specific protease, catalytic domain |Interphotoreceptor retinoid-binding protein IRBP |African clawed frog (Xenopus laevis) [TaxId: 8355]
 d2p97a1 :   (GLU122)  (LEU149)   [view usage] : d.157.1.12 |Metallo-hydrolase/oxidoreductase |Metallo-hydrolase/oxidoreductase |Ava3068-like |Hypothetical protein Ava3068 |Anabaena variabilis [TaxId: 1172]
 d1jsya1 :   (SER126)  (PRO175)   [view usage] : b.1.18.11 |Immunoglobulin-like beta-sandwich |E set domains |Arrestin/Vps26-like |Arrestin |Cow (Bos taurus), beta-arrestin 1 [TaxId: 9913]
 d3zc8a_ :    (VAL90)  (HIS139)   [view usage] : b.42.4.0 |beta-Trefoil |STI-like |automated matches |automated matches |Murraya koenigii [TaxId: 311449]
 d3r4sa2 :  (CYS1245) (PRO1288)   [view usage] : b.42.4.0 |beta-Trefoil |STI-like |automated matches |automated matches |Clostridium botulinum [TaxId: 1491]
 d3r3qa_ :    (ARG50)   (PRO88)   [view usage] : d.20.1.2 |UBC-like |UBC-like |UEV domain |automated matches |Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]
 d1alya_ :   (PHE189)  (GLY226)   [view usage] : b.22.1.1 |TNF-like |TNF-like |TNF-like |Extracellular domain of CD40 ligand |Human (Homo sapiens) [TaxId: 9606]
 d3gvka1 :   (SER664)  (VAL702)   [view usage] : b.68.1.2 |6-bladed beta-propeller |Sialidases |Endo-alpha-sialidase |automated matches |Enterobacteria phage [TaxId: 344021]
 d1fida_ :   (TYR167)  (THR192)   [view usage] : d.171.1.1 |Fibrinogen C-terminal domain-like |Fibrinogen C-terminal domain-like |Fibrinogen C-terminal domain-like |Fibrinogen C-terminal domains |Human (Homo sapiens), gamma [TaxId: 9606]
 d1vkdb_ :   (TRP226)  (TYR263)   [view usage] : b.67.2.4 |5-bladed beta-propeller |Arabinanase/levansucrase/invertase |TM1225-like predicted glycosylases |Hypothetical protein TM1225 |Thermotoga maritima [TaxId: 2336]
 d3pgzb_ :    (TYR79)  (MET113)   [view usage] : b.40.4.0 |OB-fold |Nucleic acid-binding proteins |automated matches |automated matches |Bartonella henselae [TaxId: 38323]
 d1xova1 :   (TRP223)  (ARG255)   [view usage] : b.34.11.4 |SH3-like barrel |Prokaryotic SH3-related domain |Ply C-terminal domain-like |Endolysin Ply, C-terminal domain |Bacteriophage Psa [TaxId: 171618]
 d1q16a2 :   (ALA427)  (THR472)   [view usage] : c.81.1.1 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Respiratory nitrate reductase 1 alpha chain |Escherichia coli [TaxId: 562]
 d2fcpa_ :   (TYR550)  (TYR604)   [view usage] : f.4.3.3 |Transmembrane beta-barrels |Porins |Ligand-gated protein channel |Ferric hydroxamate uptake receptor FhuA |Escherichia coli [TaxId: 562]
 d3fd7a_ :    (TYR64)  (SER103)   [view usage] : d.5.1.1 |RNase A-like |RNase A-like |Ribonuclease A-like |automated matches |Frog (Rana pipiens) [TaxId: 8404]
 d1ws9a2 :   (GLY166)  (ASP222)   [view usage] : e.6.1.1 |Acyl-CoA dehydrogenase NM domain-like |Acyl-CoA dehydrogenase NM domain-like |Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains |Acyl-CoA dehydrogenase |Thermus thermophilus [TaxId: 274]
 d1kigh_ :    (TRP29)   (ALA55)   [view usage] : b.47.1.2 |Trypsin-like serine proteases |Trypsin-like serine proteases |Eukaryotic proteases |Coagulation factor Xa, protease domain |Cow (Bos taurus) [TaxId: 9913]
 d1fi1a_ :   (TYR552)  (TYR606)   [view usage] : f.4.3.3 |Transmembrane beta-barrels |Porins |Ligand-gated protein channel |Ferric hydroxamate uptake receptor FhuA |Escherichia coli [TaxId: 562]
 d3p2da1 :   (SER127)  (PRO176)   [view usage] : b.1.18.0 |Immunoglobulin-like beta-sandwich |E set domains |automated matches |automated matches |Cow (Bos taurus) [TaxId: 9913]
 d2v65a2 :   (THR273)  (THR306)   [view usage] : d.162.1.0 |LDH C-terminal domain-like |LDH C-terminal domain-like |automated matches |automated matches |Champsocephalus gunnari [TaxId: 52237]
 d1g40a4 :   (ASN194)  (GLY223)   [view usage] : g.18.1.1 |Complement control module/SCR domain |Complement control module/SCR domain |Complement control module/SCR domain |Complement control protein |Vaccinia virus [TaxId: 10245]
 d2miba_ :    (LEU69)  (SER114)   [view usage] : b.42.1.2 |beta-Trefoil |Cytokine |Interleukin-1 (IL-1) |Interleukin-1beta |Mouse (Mus musculus) [TaxId: 10090]
 d3zbwb_ :    (GLN76)  (SER117)   [view usage] : d.5.1.1 |RNase A-like |RNase A-like |Ribonuclease A-like |automated matches |Mouse (Mus musculus) [TaxId: 10090]
 d3ir5a1 :   (GLU425)  (THR472)   [view usage] : c.81.1.1 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Formate dehydrogenase/DMSO reductase, domains 1-3 |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d1qsva_ :   (THR166)  (ARG224)   [view usage] : b.1.1.4 |Immunoglobulin-like beta-sandwich |Immunoglobulin |I set domains |Second domain of the Flt-1 receptor |Human (Homo sapiens) [TaxId: 9606]
 d1d2ia_ :   (ASP179)  (TYR223)   [view usage] : c.52.1.5 |Restriction endonuclease-like |Restriction endonuclease-like |Restriction endonuclease BglII |Restriction endonuclease BglII |Bacillus subtilis [TaxId: 1423]
 d1g4ra1 :   (SER126)  (PRO175)   [view usage] : b.1.18.11 |Immunoglobulin-like beta-sandwich |E set domains |Arrestin/Vps26-like |Arrestin |Cow (Bos taurus), beta-arrestin 1 [TaxId: 9913]
 d1s68a_ :    (VAL92)  (TYR132)   [view usage] : d.142.2.4 |ATP-grasp |DNA ligase/mRNA capping enzyme, catalytic domain |RNA ligase |RNA ligase 2, N-terminal domain |Bacteriophage T4 [TaxId: 10665]
 d1vkde_ :   (TRP226)  (TYR263)   [view usage] : b.67.2.4 |5-bladed beta-propeller |Arabinanase/levansucrase/invertase |TM1225-like predicted glycosylases |Hypothetical protein TM1225 |Thermotoga maritima [TaxId: 2336]
 d3egwa1 :   (GLU425)  (THR472)   [view usage] : c.81.1.1 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Formate dehydrogenase/DMSO reductase, domains 1-3 |Formate dehydrogenase/DMSO reductase, domains 1-3 |automated matches |Escherichia coli K-12 [TaxId: 83333]
 d1yu0a1 :   (THR107)  (ILE170)   [view usage] : b.163.1.1 |Pseudo beta-prism I |Bacteriophage trimeric proteins domain |Mtd domain-like |Major tropism determinant (Mtd), N-terminal domain |Bordetella phage bpp-1 [TaxId: 194699]
 d2fomb1 :    (ALA22)   (MET49)   [view usage] : b.47.1.3 |Trypsin-like serine proteases |Trypsin-like serine proteases |Viral proteases |NS3 protease |Dengue virus type 2 [TaxId: 11060]
 d1suja1 :   (SER123)  (ALA171)   [view usage] : b.1.18.0 |Immunoglobulin-like beta-sandwich |E set domains |automated matches |automated matches |Ambystoma tigrinum [TaxId: 8305]
 d1wgba_ :    (TYR18)   (GLY49)   [view usage] : b.45.1.2 |Split barrel-like |FMN-binding split barrel |NADH:FMN oxidoreductase-like |Putative flavoprotein TTHA0420 |Thermus thermophilus [TaxId: 274]
 d1yoaa1 :    (TYR18)   (GLY49)   [view usage] : b.45.1.2 |Split barrel-like |FMN-binding split barrel |NADH:FMN oxidoreductase-like |Putative flavoprotein TTHA0420 |Thermus thermophilus [TaxId: 274]
 d1q38a_ :    (TYR15)   (THR74)   [view usage] : b.1.2.1 |Immunoglobulin-like beta-sandwich |Fibronectin type III |Fibronectin type III |Fibronectin, different Fn3 modules |Human (Homo sapiens) [TaxId: 9606]

List of distinct SCOP folds where this concept is used (in one or more of its domains):
  b.68,    b.82,    c.81,    b.67,    b.47,   d.157,    c.14,     f.4,    b.40,     e.6,   d.171,     b.1,    b.45,    d.20,   d.110,    b.42,   d.142,    c.52,    b.22,    b.34,  
d.5, d.162, g.18, b.8, b.163, f.60